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Network neighborhood for query Sequence : SHAN1_HUMAN

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SHAN1_HUMAN
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SHAN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1041	Shared Neighborhood Hits	1041
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_MOUSE
θ value	1.17455e-116 (rank : 2)	NC score	0.505642 (rank : 205)
Query Neighborhood Hits	1041	Target Neighborhood Hits	446	Shared Neighborhood Hits	305
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SHAN2_HUMAN
θ value	3.02872e-72 (rank : 3)	NC score	0.448209 (rank : 233)
Query Neighborhood Hits	1041	Target Neighborhood Hits	346	Shared Neighborhood Hits	208
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

MUC1_HUMAN
θ value	1.86321e-21 (rank : 4)	NC score	0.134912 (rank : 472)
Query Neighborhood Hits	1041	Target Neighborhood Hits	975	Shared Neighborhood Hits	222
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ANKK1_HUMAN
θ value	2.43343e-21 (rank : 5)	NC score	0.512194 (rank : 201)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1075	Shared Neighborhood Hits	326
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANK3_HUMAN
θ value	1.2077e-20 (rank : 6)	NC score	0.741672 (rank : 37)
Query Neighborhood Hits	1041	Target Neighborhood Hits	853	Shared Neighborhood Hits	343
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR28_MOUSE
θ value	2.97466e-19 (rank : 7)	NC score	0.754082 (rank : 12)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	273
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK2_HUMAN
θ value	3.88503e-19 (rank : 8)	NC score	0.723274 (rank : 58)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1615	Shared Neighborhood Hits	498
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR28_HUMAN
θ value	3.88503e-19 (rank : 9)	NC score	0.753118 (rank : 14)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	273
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANKK1_MOUSE
θ value	5.07402e-19 (rank : 10)	NC score	0.499402 (rank : 209)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1072	Shared Neighborhood Hits	325
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANK1_MOUSE
θ value	1.13037e-18 (rank : 11)	NC score	0.745128 (rank : 32)
Query Neighborhood Hits	1041	Target Neighborhood Hits	430	Shared Neighborhood Hits	284
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR50_HUMAN
θ value	2.5182e-18 (rank : 12)	NC score	0.758285 (rank : 6)
Query Neighborhood Hits	1041	Target Neighborhood Hits	361	Shared Neighborhood Hits	278
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANKR6_HUMAN
θ value	4.29542e-18 (rank : 13)	NC score	0.768151 (rank : 2)
Query Neighborhood Hits	1041	Target Neighborhood Hits	439	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANK1_HUMAN
θ value	7.32683e-18 (rank : 14)	NC score	0.745206 (rank : 31)
Query Neighborhood Hits	1041	Target Neighborhood Hits	416	Shared Neighborhood Hits	285
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

NOTC4_MOUSE
θ value	2.13179e-17 (rank : 15)	NC score	0.423857 (rank : 238)
Query Neighborhood Hits	1041	Target Neighborhood Hits	872	Shared Neighborhood Hits	293
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANR52_HUMAN
θ value	4.74913e-17 (rank : 16)	NC score	0.748115 (rank : 25)
Query Neighborhood Hits	1041	Target Neighborhood Hits	322	Shared Neighborhood Hits	273
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

EHMT2_MOUSE
θ value	6.20254e-17 (rank : 17)	NC score	0.699296 (rank : 101)
Query Neighborhood Hits	1041	Target Neighborhood Hits	750	Shared Neighborhood Hits	372
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

RAI14_HUMAN
θ value	8.10077e-17 (rank : 18)	NC score	0.569934 (rank : 184)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1367	Shared Neighborhood Hits	350
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR52_MOUSE
θ value	1.80466e-16 (rank : 19)	NC score	0.748221 (rank : 23)
Query Neighborhood Hits	1041	Target Neighborhood Hits	318	Shared Neighborhood Hits	273
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

EHMT2_HUMAN
θ value	1.80466e-16 (rank : 20)	NC score	0.701648 (rank : 93)
Query Neighborhood Hits	1041	Target Neighborhood Hits	498	Shared Neighborhood Hits	299
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

NOTC4_HUMAN
θ value	1.80466e-16 (rank : 21)	NC score	0.418388 (rank : 241)
Query Neighborhood Hits	1041	Target Neighborhood Hits	905	Shared Neighborhood Hits	298
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANR44_HUMAN
θ value	5.25075e-16 (rank : 22)	NC score	0.755271 (rank : 8)
Query Neighborhood Hits	1041	Target Neighborhood Hits	318	Shared Neighborhood Hits	272
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

RAI14_MOUSE
θ value	6.85773e-16 (rank : 23)	NC score	0.542284 (rank : 193)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1505	Shared Neighborhood Hits	360
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANKR2_HUMAN
θ value	1.16975e-15 (rank : 24)	NC score	0.752751 (rank : 15)
Query Neighborhood Hits	1041	Target Neighborhood Hits	321	Shared Neighborhood Hits	272
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

DAPK1_MOUSE
θ value	1.16975e-15 (rank : 25)	NC score	0.360868 (rank : 263)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1138	Shared Neighborhood Hits	327
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

NOTC3_HUMAN
θ value	1.16975e-15 (rank : 26)	NC score	0.387779 (rank : 254)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1062	Shared Neighborhood Hits	341
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	1.16975e-15 (rank : 27)	NC score	0.389954 (rank : 252)
Query Neighborhood Hits	1041	Target Neighborhood Hits	975	Shared Neighborhood Hits	329
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANKR2_MOUSE
θ value	1.29331e-14 (rank : 28)	NC score	0.751993 (rank : 17)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	273
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

TNKS1_HUMAN
θ value	2.88119e-14 (rank : 29)	NC score	0.753321 (rank : 13)
Query Neighborhood Hits	1041	Target Neighborhood Hits	477	Shared Neighborhood Hits	334
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ASB10_HUMAN
θ value	3.76295e-14 (rank : 30)	NC score	0.754167 (rank : 10)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB16_MOUSE
θ value	1.09485e-13 (rank : 31)	NC score	0.743802 (rank : 33)
Query Neighborhood Hits	1041	Target Neighborhood Hits	306	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

EHMT1_HUMAN
θ value	1.09485e-13 (rank : 32)	NC score	0.703491 (rank : 90)
Query Neighborhood Hits	1041	Target Neighborhood Hits	417	Shared Neighborhood Hits	286
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

MIB1_HUMAN
θ value	1.09485e-13 (rank : 33)	NC score	0.710580 (rank : 81)
Query Neighborhood Hits	1041	Target Neighborhood Hits	470	Shared Neighborhood Hits	280
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	1.09485e-13 (rank : 34)	NC score	0.709802 (rank : 83)
Query Neighborhood Hits	1041	Target Neighborhood Hits	471	Shared Neighborhood Hits	280
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

NOTC1_HUMAN
θ value	1.09485e-13 (rank : 35)	NC score	0.382249 (rank : 258)
Query Neighborhood Hits	1041	Target Neighborhood Hits	906	Shared Neighborhood Hits	303
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANR23_HUMAN
θ value	1.42992e-13 (rank : 36)	NC score	0.755796 (rank : 7)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	271
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR23_MOUSE
θ value	1.42992e-13 (rank : 37)	NC score	0.754233 (rank : 9)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	269
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB16_HUMAN
θ value	1.86753e-13 (rank : 38)	NC score	0.740868 (rank : 39)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	265
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

TNI3K_MOUSE
θ value	1.86753e-13 (rank : 39)	NC score	0.399195 (rank : 249)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1079	Shared Neighborhood Hits	327
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CTTB2_HUMAN
θ value	2.43908e-13 (rank : 40)	NC score	0.660155 (rank : 138)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1061	Shared Neighborhood Hits	359
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANKR1_HUMAN
θ value	3.18553e-13 (rank : 41)	NC score	0.752077 (rank : 16)
Query Neighborhood Hits	1041	Target Neighborhood Hits	308	Shared Neighborhood Hits	268
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
θ value	4.16044e-13 (rank : 42)	NC score	0.751089 (rank : 18)
Query Neighborhood Hits	1041	Target Neighborhood Hits	316	Shared Neighborhood Hits	271
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB10_MOUSE
θ value	9.26847e-13 (rank : 43)	NC score	0.754118 (rank : 11)
Query Neighborhood Hits	1041	Target Neighborhood Hits	301	Shared Neighborhood Hits	273
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

NOTC2_MOUSE
θ value	9.26847e-13 (rank : 44)	NC score	0.381050 (rank : 260)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1069	Shared Neighborhood Hits	326
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PSD10_MOUSE
θ value	1.2105e-12 (rank : 45)	NC score	0.763207 (rank : 4)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	271
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKS1_HUMAN
θ value	1.58096e-12 (rank : 46)	NC score	0.725103 (rank : 56)
Query Neighborhood Hits	1041	Target Neighborhood Hits	438	Shared Neighborhood Hits	315
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

TNKS2_HUMAN
θ value	1.58096e-12 (rank : 47)	NC score	0.739901 (rank : 42)
Query Neighborhood Hits	1041	Target Neighborhood Hits	361	Shared Neighborhood Hits	280
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PSD10_HUMAN
θ value	2.0648e-12 (rank : 48)	NC score	0.764281 (rank : 3)
Query Neighborhood Hits	1041	Target Neighborhood Hits	301	Shared Neighborhood Hits	273
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR35_HUMAN
θ value	2.69671e-12 (rank : 49)	NC score	0.696592 (rank : 110)
Query Neighborhood Hits	1041	Target Neighborhood Hits	784	Shared Neighborhood Hits	306
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

NOTC2_HUMAN
θ value	3.52202e-12 (rank : 50)	NC score	0.385346 (rank : 256)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1113	Shared Neighborhood Hits	352
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANR42_MOUSE
θ value	4.59992e-12 (rank : 51)	NC score	0.743443 (rank : 34)
Query Neighborhood Hits	1041	Target Neighborhood Hits	334	Shared Neighborhood Hits	273
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASZ1_MOUSE
θ value	4.59992e-12 (rank : 52)	NC score	0.725605 (rank : 55)
Query Neighborhood Hits	1041	Target Neighborhood Hits	319	Shared Neighborhood Hits	264
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CSKI2_HUMAN
θ value	4.59992e-12 (rank : 53)	NC score	0.745246 (rank : 30)
Query Neighborhood Hits	1041	Target Neighborhood Hits	747	Shared Neighborhood Hits	486
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FANK1_HUMAN
θ value	4.59992e-12 (rank : 54)	NC score	0.748339 (rank : 22)
Query Neighborhood Hits	1041	Target Neighborhood Hits	326	Shared Neighborhood Hits	270
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANR29_HUMAN
θ value	6.00763e-12 (rank : 55)	NC score	0.760977 (rank : 5)
Query Neighborhood Hits	1041	Target Neighborhood Hits	294	Shared Neighborhood Hits	267
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ASB3_MOUSE
θ value	6.00763e-12 (rank : 56)	NC score	0.748127 (rank : 24)
Query Neighborhood Hits	1041	Target Neighborhood Hits	316	Shared Neighborhood Hits	271
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

CSKI2_MOUSE
θ value	6.00763e-12 (rank : 57)	NC score	0.740120 (rank : 41)
Query Neighborhood Hits	1041	Target Neighborhood Hits	812	Shared Neighborhood Hits	471
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB5_HUMAN
θ value	7.84624e-12 (rank : 58)	NC score	0.715303 (rank : 73)
Query Neighborhood Hits	1041	Target Neighborhood Hits	283	Shared Neighborhood Hits	262
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

DAPK1_HUMAN
θ value	7.84624e-12 (rank : 59)	NC score	0.352316 (rank : 264)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1130	Shared Neighborhood Hits	325
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ASB3_HUMAN
θ value	1.02475e-11 (rank : 60)	NC score	0.748567 (rank : 21)
Query Neighborhood Hits	1041	Target Neighborhood Hits	316	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

RIPK4_HUMAN
θ value	1.02475e-11 (rank : 61)	NC score	0.495740 (rank : 211)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1094	Shared Neighborhood Hits	326
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

TNI3K_HUMAN
θ value	1.33837e-11 (rank : 62)	NC score	0.403757 (rank : 247)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1084	Shared Neighborhood Hits	326
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ASB15_HUMAN
θ value	1.74796e-11 (rank : 63)	NC score	0.718190 (rank : 67)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	266
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

FANK1_MOUSE
θ value	3.89403e-11 (rank : 64)	NC score	0.746276 (rank : 29)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	269
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ASB11_HUMAN
θ value	5.08577e-11 (rank : 65)	NC score	0.717629 (rank : 71)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB11_MOUSE
θ value	5.08577e-11 (rank : 66)	NC score	0.718052 (rank : 68)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	250
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB15_MOUSE
θ value	5.08577e-11 (rank : 67)	NC score	0.711092 (rank : 77)
Query Neighborhood Hits	1041	Target Neighborhood Hits	292	Shared Neighborhood Hits	261
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB7_HUMAN
θ value	5.08577e-11 (rank : 68)	NC score	0.748047 (rank : 27)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	268
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	5.08577e-11 (rank : 69)	NC score	0.748079 (rank : 26)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	268
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR11_HUMAN
θ value	8.67504e-11 (rank : 70)	NC score	0.667450 (rank : 134)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1289	Shared Neighborhood Hits	414
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

INVS_HUMAN
θ value	1.47974e-10 (rank : 71)	NC score	0.742661 (rank : 35)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	301
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB2_HUMAN
θ value	1.9326e-10 (rank : 72)	NC score	0.739351 (rank : 43)
Query Neighborhood Hits	1041	Target Neighborhood Hits	309	Shared Neighborhood Hits	272
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB5_MOUSE
θ value	1.9326e-10 (rank : 73)	NC score	0.711452 (rank : 76)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	251
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB13_MOUSE
θ value	2.52405e-10 (rank : 74)	NC score	0.742154 (rank : 36)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

INVS_MOUSE
θ value	2.52405e-10 (rank : 75)	NC score	0.741452 (rank : 38)
Query Neighborhood Hits	1041	Target Neighborhood Hits	609	Shared Neighborhood Hits	331
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

BCL3_MOUSE
θ value	3.29651e-10 (rank : 76)	NC score	0.733276 (rank : 50)
Query Neighborhood Hits	1041	Target Neighborhood Hits	388	Shared Neighborhood Hits	291
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

RN5A_MOUSE
θ value	3.29651e-10 (rank : 77)	NC score	0.661406 (rank : 137)
Query Neighborhood Hits	1041	Target Neighborhood Hits	899	Shared Neighborhood Hits	306
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB8_MOUSE
θ value	4.30538e-10 (rank : 78)	NC score	0.751031 (rank : 19)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	270
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASZ1_HUMAN
θ value	5.62301e-10 (rank : 79)	NC score	0.722696 (rank : 59)
Query Neighborhood Hits	1041	Target Neighborhood Hits	341	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

NOTC1_MOUSE
θ value	5.62301e-10 (rank : 80)	NC score	0.332466 (rank : 271)
Query Neighborhood Hits	1041	Target Neighborhood Hits	916	Shared Neighborhood Hits	293
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PA2G6_HUMAN
θ value	5.62301e-10 (rank : 81)	NC score	0.730820 (rank : 51)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	266
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PA2G6_MOUSE
θ value	7.34386e-10 (rank : 82)	NC score	0.733463 (rank : 49)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	269
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB8_HUMAN
θ value	9.59137e-10 (rank : 83)	NC score	0.750612 (rank : 20)
Query Neighborhood Hits	1041	Target Neighborhood Hits	294	Shared Neighborhood Hits	270
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR26_MOUSE
θ value	1.25267e-09 (rank : 84)	NC score	0.419452 (rank : 240)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1554	Shared Neighborhood Hits	349
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB13_HUMAN
θ value	1.25267e-09 (rank : 85)	NC score	0.740702 (rank : 40)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	267
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB2_MOUSE
θ value	1.25267e-09 (rank : 86)	NC score	0.735484 (rank : 45)
Query Neighborhood Hits	1041	Target Neighborhood Hits	321	Shared Neighborhood Hits	271
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

MYPT2_HUMAN
θ value	1.25267e-09 (rank : 87)	NC score	0.698460 (rank : 104)
Query Neighborhood Hits	1041	Target Neighborhood Hits	707	Shared Neighborhood Hits	303
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ASB4_HUMAN
θ value	1.63604e-09 (rank : 88)	NC score	0.721924 (rank : 60)
Query Neighborhood Hits	1041	Target Neighborhood Hits	264	Shared Neighborhood Hits	256
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

MYPT1_HUMAN
θ value	1.63604e-09 (rank : 89)	NC score	0.695747 (rank : 112)
Query Neighborhood Hits	1041	Target Neighborhood Hits	723	Shared Neighborhood Hits	310
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

UACA_MOUSE
θ value	1.63604e-09 (rank : 90)	NC score	0.434031 (rank : 237)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1620	Shared Neighborhood Hits	340
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

MYPT1_MOUSE
θ value	2.13673e-09 (rank : 91)	NC score	0.710753 (rank : 80)
Query Neighborhood Hits	1041	Target Neighborhood Hits	539	Shared Neighborhood Hits	300
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

UACA_HUMAN
θ value	2.13673e-09 (rank : 92)	NC score	0.453627 (rank : 231)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1622	Shared Neighborhood Hits	340
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANR26_HUMAN
θ value	2.79066e-09 (rank : 93)	NC score	0.399749 (rank : 248)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1614	Shared Neighborhood Hits	344
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB4_MOUSE
θ value	3.64472e-09 (rank : 94)	NC score	0.721789 (rank : 61)
Query Neighborhood Hits	1041	Target Neighborhood Hits	265	Shared Neighborhood Hits	256
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CSKI1_HUMAN
θ value	3.64472e-09 (rank : 95)	NC score	0.739106 (rank : 44)
Query Neighborhood Hits	1041	Target Neighborhood Hits	997	Shared Neighborhood Hits	505
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	3.64472e-09 (rank : 96)	NC score	0.734368 (rank : 47)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1031	Shared Neighborhood Hits	515
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANFY1_HUMAN
θ value	4.76016e-09 (rank : 97)	NC score	0.659559 (rank : 140)
Query Neighborhood Hits	1041	Target Neighborhood Hits	480	Shared Neighborhood Hits	276
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKS3_MOUSE
θ value	4.76016e-09 (rank : 98)	NC score	0.718288 (rank : 66)
Query Neighborhood Hits	1041	Target Neighborhood Hits	355	Shared Neighborhood Hits	268
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANFY1_MOUSE
θ value	6.21693e-09 (rank : 99)	NC score	0.659916 (rank : 139)
Query Neighborhood Hits	1041	Target Neighborhood Hits	480	Shared Neighborhood Hits	276
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKS1_MOUSE
θ value	6.21693e-09 (rank : 100)	NC score	0.710879 (rank : 79)
Query Neighborhood Hits	1041	Target Neighborhood Hits	453	Shared Neighborhood Hits	319
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

BCL3_HUMAN
θ value	6.21693e-09 (rank : 101)	NC score	0.734534 (rank : 46)
Query Neighborhood Hits	1041	Target Neighborhood Hits	324	Shared Neighborhood Hits	281
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

RN5A_HUMAN
θ value	6.21693e-09 (rank : 102)	NC score	0.700919 (rank : 97)
Query Neighborhood Hits	1041	Target Neighborhood Hits	608	Shared Neighborhood Hits	288
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR12_HUMAN
θ value	8.11959e-09 (rank : 103)	NC score	0.620707 (rank : 162)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1081	Shared Neighborhood Hits	323
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

NHERF_HUMAN
θ value	8.11959e-09 (rank : 104)	NC score	0.276211 (rank : 282)
Query Neighborhood Hits	1041	Target Neighborhood Hits	190	Shared Neighborhood Hits	139
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

TRPA1_HUMAN
θ value	8.11959e-09 (rank : 105)	NC score	0.720693 (rank : 63)
Query Neighborhood Hits	1041	Target Neighborhood Hits	339	Shared Neighborhood Hits	269
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

POT15_HUMAN
θ value	1.06045e-08 (rank : 106)	NC score	0.641933 (rank : 150)
Query Neighborhood Hits	1041	Target Neighborhood Hits	893	Shared Neighborhood Hits	309
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

POTE8_HUMAN
θ value	1.06045e-08 (rank : 107)	NC score	0.678443 (rank : 127)
Query Neighborhood Hits	1041	Target Neighborhood Hits	337	Shared Neighborhood Hits	267
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

TRPA1_MOUSE
θ value	1.80886e-08 (rank : 108)	NC score	0.721236 (rank : 62)
Query Neighborhood Hits	1041	Target Neighborhood Hits	343	Shared Neighborhood Hits	271
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ASB9_HUMAN
θ value	3.08544e-08 (rank : 109)	NC score	0.714468 (rank : 75)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	248
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

GABP2_HUMAN
θ value	3.08544e-08 (rank : 110)	NC score	0.726309 (rank : 54)
Query Neighborhood Hits	1041	Target Neighborhood Hits	454	Shared Neighborhood Hits	278
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	4.0297e-08 (rank : 111)	NC score	0.728265 (rank : 52)
Query Neighborhood Hits	1041	Target Neighborhood Hits	429	Shared Neighborhood Hits	277
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANRA2_HUMAN
θ value	5.26297e-08 (rank : 112)	NC score	0.702009 (rank : 92)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	260
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

MIB2_MOUSE
θ value	5.26297e-08 (rank : 113)	NC score	0.696668 (rank : 109)
Query Neighborhood Hits	1041	Target Neighborhood Hits	409	Shared Neighborhood Hits	270
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANR21_HUMAN
θ value	6.87365e-08 (rank : 114)	NC score	0.639437 (rank : 151)
Query Neighborhood Hits	1041	Target Neighborhood Hits	864	Shared Neighborhood Hits	308
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ARHG7_HUMAN
θ value	6.87365e-08 (rank : 115)	NC score	0.211023 (rank : 318)
Query Neighborhood Hits	1041	Target Neighborhood Hits	347	Shared Neighborhood Hits	158
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

NHERF_MOUSE
θ value	8.97725e-08 (rank : 116)	NC score	0.275421 (rank : 283)
Query Neighborhood Hits	1041	Target Neighborhood Hits	195	Shared Neighborhood Hits	139
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

ANKS6_MOUSE
θ value	1.17247e-07 (rank : 117)	NC score	0.720099 (rank : 64)
Query Neighborhood Hits	1041	Target Neighborhood Hits	435	Shared Neighborhood Hits	320
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR42_HUMAN
θ value	1.17247e-07 (rank : 118)	NC score	0.734301 (rank : 48)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	265
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ILK_MOUSE
θ value	1.17247e-07 (rank : 119)	NC score	0.461484 (rank : 225)
Query Neighborhood Hits	1041	Target Neighborhood Hits	858	Shared Neighborhood Hits	313
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ANR41_HUMAN
θ value	1.53129e-07 (rank : 120)	NC score	0.664593 (rank : 136)
Query Neighborhood Hits	1041	Target Neighborhood Hits	332	Shared Neighborhood Hits	265
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

PDZD1_HUMAN
θ value	1.53129e-07 (rank : 121)	NC score	0.266758 (rank : 286)
Query Neighborhood Hits	1041	Target Neighborhood Hits	190	Shared Neighborhood Hits	138
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ANR16_HUMAN
θ value	1.99992e-07 (rank : 122)	NC score	0.747492 (rank : 28)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	267
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANRA2_MOUSE
θ value	1.99992e-07 (rank : 123)	NC score	0.701268 (rank : 95)
Query Neighborhood Hits	1041	Target Neighborhood Hits	287	Shared Neighborhood Hits	259
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ARHG6_HUMAN
θ value	1.99992e-07 (rank : 124)	NC score	0.212920 (rank : 311)
Query Neighborhood Hits	1041	Target Neighborhood Hits	376	Shared Neighborhood Hits	150
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHGC_HUMAN
θ value	1.99992e-07 (rank : 125)	NC score	0.207374 (rank : 327)
Query Neighborhood Hits	1041	Target Neighborhood Hits	351	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	1.99992e-07 (rank : 126)	NC score	0.207229 (rank : 328)
Query Neighborhood Hits	1041	Target Neighborhood Hits	344	Shared Neighborhood Hits	164
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BARD1_MOUSE
θ value	1.99992e-07 (rank : 127)	NC score	0.672177 (rank : 131)
Query Neighborhood Hits	1041	Target Neighborhood Hits	411	Shared Neighborhood Hits	270
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ILK1_HUMAN
θ value	1.99992e-07 (rank : 128)	NC score	0.462328 (rank : 224)
Query Neighborhood Hits	1041	Target Neighborhood Hits	857	Shared Neighborhood Hits	313
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	1.99992e-07 (rank : 129)	NC score	0.477493 (rank : 218)
Query Neighborhood Hits	1041	Target Neighborhood Hits	848	Shared Neighborhood Hits	313
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ARHG6_MOUSE
θ value	2.61198e-07 (rank : 130)	NC score	0.214893 (rank : 310)
Query Neighborhood Hits	1041	Target Neighborhood Hits	394	Shared Neighborhood Hits	156
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_MOUSE
θ value	2.61198e-07 (rank : 131)	NC score	0.211529 (rank : 313)
Query Neighborhood Hits	1041	Target Neighborhood Hits	396	Shared Neighborhood Hits	161
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

BARD1_HUMAN
θ value	3.41135e-07 (rank : 132)	NC score	0.674799 (rank : 128)
Query Neighborhood Hits	1041	Target Neighborhood Hits	427	Shared Neighborhood Hits	273
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

IKBA_MOUSE
θ value	3.41135e-07 (rank : 133)	NC score	0.698275 (rank : 105)
Query Neighborhood Hits	1041	Target Neighborhood Hits	283	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

NFKB2_HUMAN
θ value	3.41135e-07 (rank : 134)	NC score	0.626156 (rank : 157)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	274
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NFKB2_MOUSE
θ value	3.41135e-07 (rank : 135)	NC score	0.613844 (rank : 166)
Query Neighborhood Hits	1041	Target Neighborhood Hits	326	Shared Neighborhood Hits	267
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

OSBL1_HUMAN
θ value	3.41135e-07 (rank : 136)	NC score	0.571445 (rank : 183)
Query Neighborhood Hits	1041	Target Neighborhood Hits	368	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PP16A_MOUSE
θ value	3.41135e-07 (rank : 137)	NC score	0.705595 (rank : 88)
Query Neighborhood Hits	1041	Target Neighborhood Hits	318	Shared Neighborhood Hits	270
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ACBD6_MOUSE
θ value	4.45536e-07 (rank : 138)	NC score	0.683963 (rank : 125)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	271
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

DGKD_HUMAN
θ value	4.45536e-07 (rank : 139)	NC score	0.123743 (rank : 516)
Query Neighborhood Hits	1041	Target Neighborhood Hits	231	Shared Neighborhood Hits	53
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

ASB9_MOUSE
θ value	5.81887e-07 (rank : 140)	NC score	0.705613 (rank : 87)
Query Neighborhood Hits	1041	Target Neighborhood Hits	257	Shared Neighborhood Hits	243
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

POT14_HUMAN
θ value	5.81887e-07 (rank : 141)	NC score	0.625018 (rank : 158)
Query Neighborhood Hits	1041	Target Neighborhood Hits	403	Shared Neighborhood Hits	270
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

TRPV6_MOUSE
θ value	7.59969e-07 (rank : 142)	NC score	0.486262 (rank : 214)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	237
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ZDH17_HUMAN
θ value	7.59969e-07 (rank : 143)	NC score	0.642596 (rank : 147)
Query Neighborhood Hits	1041	Target Neighborhood Hits	334	Shared Neighborhood Hits	268
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR10_HUMAN
θ value	9.92553e-07 (rank : 144)	NC score	0.703008 (rank : 91)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	262
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR46_MOUSE
θ value	9.92553e-07 (rank : 145)	NC score	0.697964 (rank : 106)
Query Neighborhood Hits	1041	Target Neighborhood Hits	274	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

OSBL1_MOUSE
θ value	9.92553e-07 (rank : 146)	NC score	0.561690 (rank : 187)
Query Neighborhood Hits	1041	Target Neighborhood Hits	336	Shared Neighborhood Hits	269
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

SH3K1_HUMAN
θ value	9.92553e-07 (rank : 147)	NC score	0.235159 (rank : 297)
Query Neighborhood Hits	1041	Target Neighborhood Hits	341	Shared Neighborhood Hits	161
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

IKBA_HUMAN
θ value	1.29631e-06 (rank : 148)	NC score	0.707094 (rank : 84)
Query Neighborhood Hits	1041	Target Neighborhood Hits	280	Shared Neighborhood Hits	265
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

MAGE1_HUMAN
θ value	1.29631e-06 (rank : 149)	NC score	0.105966 (rank : 570)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1389	Shared Neighborhood Hits	299
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ANR39_HUMAN
θ value	1.69304e-06 (rank : 150)	NC score	0.727109 (rank : 53)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	270
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

A20A3_HUMAN
θ value	2.21117e-06 (rank : 151)	NC score	0.586513 (rank : 175)
Query Neighborhood Hits	1041	Target Neighborhood Hits	692	Shared Neighborhood Hits	295
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	2.21117e-06 (rank : 152)	NC score	0.582877 (rank : 179)
Query Neighborhood Hits	1041	Target Neighborhood Hits	710	Shared Neighborhood Hits	295
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANKR5_HUMAN
θ value	2.21117e-06 (rank : 153)	NC score	0.700304 (rank : 98)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	267
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR10_MOUSE
θ value	2.21117e-06 (rank : 154)	NC score	0.701174 (rank : 96)
Query Neighborhood Hits	1041	Target Neighborhood Hits	273	Shared Neighborhood Hits	263
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB14_MOUSE
θ value	2.21117e-06 (rank : 155)	NC score	0.704378 (rank : 89)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	264
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

NHRF2_HUMAN
θ value	2.21117e-06 (rank : 156)	NC score	0.266148 (rank : 287)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	138
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

ANKY2_MOUSE
θ value	2.88788e-06 (rank : 157)	NC score	0.623056 (rank : 159)
Query Neighborhood Hits	1041	Target Neighborhood Hits	316	Shared Neighborhood Hits	248
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

IKBE_MOUSE
θ value	2.88788e-06 (rank : 158)	NC score	0.699649 (rank : 99)
Query Neighborhood Hits	1041	Target Neighborhood Hits	308	Shared Neighborhood Hits	275
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

MAGI1_HUMAN
θ value	2.88788e-06 (rank : 159)	NC score	0.220553 (rank : 305)
Query Neighborhood Hits	1041	Target Neighborhood Hits	388	Shared Neighborhood Hits	168
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

NCK2_HUMAN
θ value	2.88788e-06 (rank : 160)	NC score	0.194729 (rank : 334)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	134
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

SH3K1_MOUSE
θ value	2.88788e-06 (rank : 161)	NC score	0.229133 (rank : 302)
Query Neighborhood Hits	1041	Target Neighborhood Hits	332	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

VAV3_HUMAN
θ value	2.88788e-06 (rank : 162)	NC score	0.183115 (rank : 351)
Query Neighborhood Hits	1041	Target Neighborhood Hits	398	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

A20A2_HUMAN
θ value	3.77169e-06 (rank : 163)	NC score	0.585078 (rank : 176)
Query Neighborhood Hits	1041	Target Neighborhood Hits	716	Shared Neighborhood Hits	291
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

NCK1_HUMAN
θ value	3.77169e-06 (rank : 164)	NC score	0.197460 (rank : 330)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	147
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

PDZD1_MOUSE
θ value	3.77169e-06 (rank : 165)	NC score	0.267543 (rank : 284)
Query Neighborhood Hits	1041	Target Neighborhood Hits	191	Shared Neighborhood Hits	137
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ANKY2_HUMAN
θ value	4.92598e-06 (rank : 166)	NC score	0.642155 (rank : 149)
Query Neighborhood Hits	1041	Target Neighborhood Hits	306	Shared Neighborhood Hits	250
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR39_MOUSE
θ value	4.92598e-06 (rank : 167)	NC score	0.723443 (rank : 57)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	269
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

DGKH_HUMAN
θ value	4.92598e-06 (rank : 168)	NC score	0.115060 (rank : 538)
Query Neighborhood Hits	1041	Target Neighborhood Hits	255	Shared Neighborhood Hits	59
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

PRRT3_HUMAN
θ value	4.92598e-06 (rank : 169)	NC score	0.130644 (rank : 494)
Query Neighborhood Hits	1041	Target Neighborhood Hits	998	Shared Neighborhood Hits	246
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

VAV3_MOUSE
θ value	4.92598e-06 (rank : 170)	NC score	0.182125 (rank : 354)
Query Neighborhood Hits	1041	Target Neighborhood Hits	404	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

A20A1_HUMAN
θ value	6.43352e-06 (rank : 171)	NC score	0.584631 (rank : 177)
Query Neighborhood Hits	1041	Target Neighborhood Hits	698	Shared Neighborhood Hits	292
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ANR47_MOUSE
θ value	6.43352e-06 (rank : 172)	NC score	0.623016 (rank : 160)
Query Neighborhood Hits	1041	Target Neighborhood Hits	350	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB12_HUMAN
θ value	6.43352e-06 (rank : 173)	NC score	0.692815 (rank : 115)
Query Neighborhood Hits	1041	Target Neighborhood Hits	263	Shared Neighborhood Hits	253
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

PSCBP_MOUSE
θ value	6.43352e-06 (rank : 174)	NC score	0.231640 (rank : 299)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	98
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

USH1C_MOUSE
θ value	6.43352e-06 (rank : 175)	NC score	0.239577 (rank : 293)
Query Neighborhood Hits	1041	Target Neighborhood Hits	557	Shared Neighborhood Hits	209
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

AN36B_HUMAN
θ value	8.40245e-06 (rank : 176)	NC score	0.697676 (rank : 108)
Query Neighborhood Hits	1041	Target Neighborhood Hits	294	Shared Neighborhood Hits	265
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANKR7_HUMAN
θ value	8.40245e-06 (rank : 177)	NC score	0.714748 (rank : 74)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	265
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ASB1_MOUSE
θ value	8.40245e-06 (rank : 178)	NC score	0.694124 (rank : 114)
Query Neighborhood Hits	1041	Target Neighborhood Hits	292	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CENB5_HUMAN
θ value	8.40245e-06 (rank : 179)	NC score	0.487386 (rank : 213)
Query Neighborhood Hits	1041	Target Neighborhood Hits	395	Shared Neighborhood Hits	265
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

VAV_MOUSE
θ value	8.40245e-06 (rank : 180)	NC score	0.192319 (rank : 342)
Query Neighborhood Hits	1041	Target Neighborhood Hits	430	Shared Neighborhood Hits	152
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ACBD6_HUMAN
θ value	1.09739e-05 (rank : 181)	NC score	0.679605 (rank : 126)
Query Neighborhood Hits	1041	Target Neighborhood Hits	304	Shared Neighborhood Hits	268
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR18_HUMAN
θ value	1.09739e-05 (rank : 182)	NC score	0.549168 (rank : 191)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1106	Shared Neighborhood Hits	312
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR46_HUMAN
θ value	1.09739e-05 (rank : 183)	NC score	0.699455 (rank : 100)
Query Neighborhood Hits	1041	Target Neighborhood Hits	281	Shared Neighborhood Hits	263
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

LAP4_HUMAN
θ value	1.09739e-05 (rank : 184)	NC score	0.139042 (rank : 457)
Query Neighborhood Hits	1041	Target Neighborhood Hits	608	Shared Neighborhood Hits	198
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MY18A_MOUSE
θ value	1.09739e-05 (rank : 185)	NC score	0.082278 (rank : 694)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1989	Shared Neighborhood Hits	244
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NFH_MOUSE
θ value	1.09739e-05 (rank : 186)	NC score	0.096107 (rank : 616)
Query Neighborhood Hits	1041	Target Neighborhood Hits	2247	Shared Neighborhood Hits	355
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PP16A_HUMAN
θ value	1.09739e-05 (rank : 187)	NC score	0.699274 (rank : 102)
Query Neighborhood Hits	1041	Target Neighborhood Hits	340	Shared Neighborhood Hits	275
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ZDH13_HUMAN
θ value	1.09739e-05 (rank : 188)	NC score	0.637175 (rank : 152)
Query Neighborhood Hits	1041	Target Neighborhood Hits	322	Shared Neighborhood Hits	267
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ZDH17_MOUSE
θ value	1.09739e-05 (rank : 189)	NC score	0.637076 (rank : 153)
Query Neighborhood Hits	1041	Target Neighborhood Hits	328	Shared Neighborhood Hits	265
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

VAV_HUMAN
θ value	1.43324e-05 (rank : 190)	NC score	0.190364 (rank : 343)
Query Neighborhood Hits	1041	Target Neighborhood Hits	452	Shared Neighborhood Hits	149
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ANKS6_HUMAN
θ value	1.87187e-05 (rank : 191)	NC score	0.716259 (rank : 72)
Query Neighborhood Hits	1041	Target Neighborhood Hits	411	Shared Neighborhood Hits	310
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR47_HUMAN
θ value	1.87187e-05 (rank : 192)	NC score	0.611312 (rank : 167)
Query Neighborhood Hits	1041	Target Neighborhood Hits	369	Shared Neighborhood Hits	275
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ARHGB_HUMAN
θ value	1.87187e-05 (rank : 193)	NC score	0.210022 (rank : 322)
Query Neighborhood Hits	1041	Target Neighborhood Hits	375	Shared Neighborhood Hits	186
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

GRASP_HUMAN
θ value	1.87187e-05 (rank : 194)	NC score	0.239545 (rank : 294)
Query Neighborhood Hits	1041	Target Neighborhood Hits	147	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

NHRF2_MOUSE
θ value	1.87187e-05 (rank : 195)	NC score	0.259900 (rank : 288)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

ZDH13_MOUSE
θ value	1.87187e-05 (rank : 196)	NC score	0.633613 (rank : 154)
Query Neighborhood Hits	1041	Target Neighborhood Hits	329	Shared Neighborhood Hits	270
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANR49_HUMAN
θ value	2.44474e-05 (rank : 197)	NC score	0.717690 (rank : 70)
Query Neighborhood Hits	1041	Target Neighborhood Hits	282	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASB1_HUMAN
θ value	2.44474e-05 (rank : 198)	NC score	0.695414 (rank : 113)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

RGS3_MOUSE
θ value	2.44474e-05 (rank : 199)	NC score	0.130741 (rank : 492)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1621	Shared Neighborhood Hits	363
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

VAV2_HUMAN
θ value	2.44474e-05 (rank : 200)	NC score	0.183380 (rank : 349)
Query Neighborhood Hits	1041	Target Neighborhood Hits	453	Shared Neighborhood Hits	150
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ASB6_MOUSE
θ value	3.19293e-05 (rank : 201)	NC score	0.652476 (rank : 143)
Query Neighborhood Hits	1041	Target Neighborhood Hits	264	Shared Neighborhood Hits	237
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

MAGI2_HUMAN
θ value	3.19293e-05 (rank : 202)	NC score	0.217296 (rank : 307)
Query Neighborhood Hits	1041	Target Neighborhood Hits	373	Shared Neighborhood Hits	182
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	3.19293e-05 (rank : 203)	NC score	0.211251 (rank : 316)
Query Neighborhood Hits	1041	Target Neighborhood Hits	370	Shared Neighborhood Hits	173
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

TRPV5_MOUSE
θ value	3.19293e-05 (rank : 204)	NC score	0.443080 (rank : 236)
Query Neighborhood Hits	1041	Target Neighborhood Hits	278	Shared Neighborhood Hits	233
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

WHRN_MOUSE
θ value	3.19293e-05 (rank : 205)	NC score	0.239154 (rank : 295)
Query Neighborhood Hits	1041	Target Neighborhood Hits	412	Shared Neighborhood Hits	201
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

ANR19_HUMAN
θ value	4.1701e-05 (rank : 206)	NC score	0.672102 (rank : 132)
Query Neighborhood Hits	1041	Target Neighborhood Hits	276	Shared Neighborhood Hits	258
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

CDN2C_HUMAN
θ value	4.1701e-05 (rank : 207)	NC score	0.701297 (rank : 94)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	251
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

GRASP_MOUSE
θ value	4.1701e-05 (rank : 208)	NC score	0.236038 (rank : 296)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

IKBE_HUMAN
θ value	4.1701e-05 (rank : 209)	NC score	0.684064 (rank : 124)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	262
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

MAGI1_MOUSE
θ value	4.1701e-05 (rank : 210)	NC score	0.219758 (rank : 306)
Query Neighborhood Hits	1041	Target Neighborhood Hits	403	Shared Neighborhood Hits	165
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

TEX14_HUMAN
θ value	4.1701e-05 (rank : 211)	NC score	0.385616 (rank : 255)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1103	Shared Neighborhood Hits	330
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

LAP4_MOUSE
θ value	5.44631e-05 (rank : 212)	NC score	0.133958 (rank : 476)
Query Neighborhood Hits	1041	Target Neighborhood Hits	590	Shared Neighborhood Hits	191
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PP16B_HUMAN
θ value	5.44631e-05 (rank : 213)	NC score	0.691595 (rank : 117)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	273
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

PSCBP_HUMAN
θ value	5.44631e-05 (rank : 214)	NC score	0.226219 (rank : 303)
Query Neighborhood Hits	1041	Target Neighborhood Hits	123	Shared Neighborhood Hits	101
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

VAV2_MOUSE
θ value	5.44631e-05 (rank : 215)	NC score	0.181305 (rank : 356)
Query Neighborhood Hits	1041	Target Neighborhood Hits	456	Shared Neighborhood Hits	153
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ASB12_MOUSE
θ value	7.1131e-05 (rank : 216)	NC score	0.687936 (rank : 121)
Query Neighborhood Hits	1041	Target Neighborhood Hits	261	Shared Neighborhood Hits	251
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB6_HUMAN
θ value	7.1131e-05 (rank : 217)	NC score	0.652677 (rank : 142)
Query Neighborhood Hits	1041	Target Neighborhood Hits	256	Shared Neighborhood Hits	238
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

MIB2_HUMAN
θ value	7.1131e-05 (rank : 218)	NC score	0.695859 (rank : 111)
Query Neighborhood Hits	1041	Target Neighborhood Hits	438	Shared Neighborhood Hits	274
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

PDZD3_MOUSE
θ value	7.1131e-05 (rank : 219)	NC score	0.251826 (rank : 289)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	132
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

CDN2C_MOUSE
θ value	9.29e-05 (rank : 220)	NC score	0.698513 (rank : 103)
Query Neighborhood Hits	1041	Target Neighborhood Hits	270	Shared Neighborhood Hits	256
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CT086_HUMAN
θ value	9.29e-05 (rank : 221)	NC score	0.711091 (rank : 78)
Query Neighborhood Hits	1041	Target Neighborhood Hits	277	Shared Neighborhood Hits	263
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

FRS3_HUMAN
θ value	9.29e-05 (rank : 222)	NC score	0.045414 (rank : 1161)
Query Neighborhood Hits	1041	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

MAST3_HUMAN
θ value	9.29e-05 (rank : 223)	NC score	0.071148 (rank : 790)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1128	Shared Neighborhood Hits	243
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

PDZD3_HUMAN
θ value	9.29e-05 (rank : 224)	NC score	0.246463 (rank : 291)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	136
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

WHRN_HUMAN
θ value	9.29e-05 (rank : 225)	NC score	0.234940 (rank : 298)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	175
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

DDEF1_MOUSE
θ value	0.000121331 (rank : 226)	NC score	0.339226 (rank : 267)
Query Neighborhood Hits	1041	Target Neighborhood Hits	592	Shared Neighborhood Hits	346
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

NFKB1_MOUSE
θ value	0.000121331 (rank : 227)	NC score	0.621829 (rank : 161)
Query Neighborhood Hits	1041	Target Neighborhood Hits	300	Shared Neighborhood Hits	262
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

SI1L2_HUMAN
θ value	0.000121331 (rank : 228)	NC score	0.103695 (rank : 578)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

FYN_HUMAN
θ value	0.000158464 (rank : 229)	NC score	0.083812 (rank : 680)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1078	Shared Neighborhood Hits	186
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	0.000158464 (rank : 230)	NC score	0.084541 (rank : 673)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1073	Shared Neighborhood Hits	182
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

MAST2_MOUSE
θ value	0.000158464 (rank : 231)	NC score	0.065647 (rank : 846)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1110	Shared Neighborhood Hits	218
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NFKB1_HUMAN
θ value	0.000158464 (rank : 232)	NC score	0.619924 (rank : 163)
Query Neighborhood Hits	1041	Target Neighborhood Hits	306	Shared Neighborhood Hits	269
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

PDZD2_HUMAN
θ value	0.000158464 (rank : 233)	NC score	0.211437 (rank : 314)
Query Neighborhood Hits	1041	Target Neighborhood Hits	772	Shared Neighborhood Hits	261
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

POT22_HUMAN
θ value	0.000158464 (rank : 234)	NC score	0.588906 (rank : 174)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	251
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

PP16B_MOUSE
θ value	0.000158464 (rank : 235)	NC score	0.689639 (rank : 119)
Query Neighborhood Hits	1041	Target Neighborhood Hits	302	Shared Neighborhood Hits	272
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR49_MOUSE
θ value	0.00020696 (rank : 236)	NC score	0.717963 (rank : 69)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	260
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

RFXK_MOUSE
θ value	0.00020696 (rank : 237)	NC score	0.687785 (rank : 122)
Query Neighborhood Hits	1041	Target Neighborhood Hits	273	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

USH1C_HUMAN
θ value	0.00020696 (rank : 238)	NC score	0.230683 (rank : 300)
Query Neighborhood Hits	1041	Target Neighborhood Hits	327	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

AN36A_HUMAN
θ value	0.000270298 (rank : 239)	NC score	0.671767 (rank : 133)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

HXB3_HUMAN
θ value	0.000270298 (rank : 240)	NC score	0.018827 (rank : 1325)
Query Neighborhood Hits	1041	Target Neighborhood Hits	559	Shared Neighborhood Hits	80
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

LNX1_HUMAN
θ value	0.000270298 (rank : 241)	NC score	0.164795 (rank : 397)
Query Neighborhood Hits	1041	Target Neighborhood Hits	379	Shared Neighborhood Hits	123
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAST2_HUMAN
θ value	0.000270298 (rank : 242)	NC score	0.066717 (rank : 839)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1189	Shared Neighborhood Hits	227
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MDC1_HUMAN
θ value	0.000270298 (rank : 243)	NC score	0.132300 (rank : 483)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1446	Shared Neighborhood Hits	277
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MTPN_HUMAN
θ value	0.000270298 (rank : 244)	NC score	0.705673 (rank : 86)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	255
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

NACAM_MOUSE
θ value	0.000270298 (rank : 245)	NC score	0.153043 (rank : 423)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1866	Shared Neighborhood Hits	383
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RFXK_HUMAN
θ value	0.000270298 (rank : 246)	NC score	0.692372 (rank : 116)
Query Neighborhood Hits	1041	Target Neighborhood Hits	282	Shared Neighborhood Hits	258
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

SI1L2_MOUSE
θ value	0.000270298 (rank : 247)	NC score	0.101717 (rank : 591)
Query Neighborhood Hits	1041	Target Neighborhood Hits	124	Shared Neighborhood Hits	48
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

AN13C_HUMAN
θ value	0.00035302 (rank : 248)	NC score	0.458836 (rank : 228)
Query Neighborhood Hits	1041	Target Neighborhood Hits	241	Shared Neighborhood Hits	232
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANR15_HUMAN
θ value	0.00035302 (rank : 249)	NC score	0.617120 (rank : 164)
Query Neighborhood Hits	1041	Target Neighborhood Hits	478	Shared Neighborhood Hits	277
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

BCOR_HUMAN
θ value	0.00035302 (rank : 250)	NC score	0.602972 (rank : 170)
Query Neighborhood Hits	1041	Target Neighborhood Hits	609	Shared Neighborhood Hits	325
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	0.00035302 (rank : 251)	NC score	0.608651 (rank : 168)
Query Neighborhood Hits	1041	Target Neighborhood Hits	521	Shared Neighborhood Hits	305
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

IKBB_MOUSE
θ value	0.00035302 (rank : 252)	NC score	0.672863 (rank : 129)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	264
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

M3K11_HUMAN
θ value	0.00035302 (rank : 253)	NC score	0.095434 (rank : 620)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1136	Shared Neighborhood Hits	230
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MAST1_HUMAN
θ value	0.00035302 (rank : 254)	NC score	0.068332 (rank : 824)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1146	Shared Neighborhood Hits	226
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NCF1_HUMAN
θ value	0.00035302 (rank : 255)	NC score	0.193564 (rank : 338)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	126
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

OSTF1_MOUSE
θ value	0.00035302 (rank : 256)	NC score	0.665546 (rank : 135)
Query Neighborhood Hits	1041	Target Neighborhood Hits	467	Shared Neighborhood Hits	370
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

SI1L1_HUMAN
θ value	0.00035302 (rank : 257)	NC score	0.101111 (rank : 595)
Query Neighborhood Hits	1041	Target Neighborhood Hits	162	Shared Neighborhood Hits	54
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
θ value	0.00035302 (rank : 258)	NC score	0.100544 (rank : 596)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

ABL1_HUMAN
θ value	0.000461057 (rank : 259)	NC score	0.074471 (rank : 760)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1220	Shared Neighborhood Hits	208
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	0.000461057 (rank : 260)	NC score	0.076300 (rank : 743)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1178	Shared Neighborhood Hits	210
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ANKR5_MOUSE
θ value	0.000461057 (rank : 261)	NC score	0.697739 (rank : 107)
Query Neighborhood Hits	1041	Target Neighborhood Hits	298	Shared Neighborhood Hits	270
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS3_HUMAN
θ value	0.000461057 (rank : 262)	NC score	0.710350 (rank : 82)
Query Neighborhood Hits	1041	Target Neighborhood Hits	355	Shared Neighborhood Hits	274
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CDN2D_MOUSE
θ value	0.000461057 (rank : 263)	NC score	0.688720 (rank : 120)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	253
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

GOPC_HUMAN
θ value	0.000461057 (rank : 264)	NC score	0.211366 (rank : 315)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	0.000461057 (rank : 265)	NC score	0.208039 (rank : 324)
Query Neighborhood Hits	1041	Target Neighborhood Hits	323	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

ITSN1_MOUSE
θ value	0.000461057 (rank : 266)	NC score	0.166191 (rank : 392)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1669	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

M3KL4_HUMAN
θ value	0.000461057 (rank : 267)	NC score	0.089486 (rank : 652)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1087	Shared Neighborhood Hits	189
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MPP8_HUMAN
θ value	0.000461057 (rank : 268)	NC score	0.583780 (rank : 178)
Query Neighborhood Hits	1041	Target Neighborhood Hits	948	Shared Neighborhood Hits	294
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

OSTF1_HUMAN
θ value	0.000461057 (rank : 269)	NC score	0.654034 (rank : 141)
Query Neighborhood Hits	1041	Target Neighborhood Hits	466	Shared Neighborhood Hits	370
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PDLI5_HUMAN
θ value	0.000461057 (rank : 270)	NC score	0.089260 (rank : 654)
Query Neighborhood Hits	1041	Target Neighborhood Hits	322	Shared Neighborhood Hits	127
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PLCG2_HUMAN
θ value	0.000461057 (rank : 271)	NC score	0.139133 (rank : 455)
Query Neighborhood Hits	1041	Target Neighborhood Hits	280	Shared Neighborhood Hits	115
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

SI1L3_HUMAN
θ value	0.000461057 (rank : 272)	NC score	0.109886 (rank : 557)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	106
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

TRPV5_HUMAN
θ value	0.000461057 (rank : 273)	NC score	0.417028 (rank : 242)
Query Neighborhood Hits	1041	Target Neighborhood Hits	261	Shared Neighborhood Hits	208
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

MY18A_HUMAN
θ value	0.000602161 (rank : 274)	NC score	0.076147 (rank : 745)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1929	Shared Neighborhood Hits	230
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TRPV6_HUMAN
θ value	0.000602161 (rank : 275)	NC score	0.414486 (rank : 244)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	210
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

CEL_HUMAN
θ value	0.000786445 (rank : 276)	NC score	0.062400 (rank : 894)
Query Neighborhood Hits	1041	Target Neighborhood Hits	896	Shared Neighborhood Hits	196
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

K1802_MOUSE
θ value	0.000786445 (rank : 277)	NC score	0.088972 (rank : 655)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1596	Shared Neighborhood Hits	279
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAST4_HUMAN
θ value	0.000786445 (rank : 278)	NC score	0.083704 (rank : 681)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1804	Shared Neighborhood Hits	366
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RIMB1_HUMAN
θ value	0.000786445 (rank : 279)	NC score	0.129556 (rank : 499)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1479	Shared Neighborhood Hits	291
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SON_HUMAN
θ value	0.000786445 (rank : 280)	NC score	0.109024 (rank : 560)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1568	Shared Neighborhood Hits	306
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

AN13B_HUMAN
θ value	0.00102713 (rank : 281)	NC score	0.459223 (rank : 227)
Query Neighborhood Hits	1041	Target Neighborhood Hits	265	Shared Neighborhood Hits	247
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	0.00102713 (rank : 282)	NC score	0.460435 (rank : 226)
Query Neighborhood Hits	1041	Target Neighborhood Hits	276	Shared Neighborhood Hits	249
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13C_MOUSE
θ value	0.00102713 (rank : 283)	NC score	0.448363 (rank : 232)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	231
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

CENB2_HUMAN
θ value	0.00102713 (rank : 284)	NC score	0.471444 (rank : 219)
Query Neighborhood Hits	1041	Target Neighborhood Hits	425	Shared Neighborhood Hits	255
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

GIT1_HUMAN
θ value	0.00102713 (rank : 285)	NC score	0.443646 (rank : 235)
Query Neighborhood Hits	1041	Target Neighborhood Hits	336	Shared Neighborhood Hits	245
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.00102713 (rank : 286)	NC score	0.445326 (rank : 234)
Query Neighborhood Hits	1041	Target Neighborhood Hits	341	Shared Neighborhood Hits	248
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

IKBB_HUMAN
θ value	0.00102713 (rank : 287)	NC score	0.672201 (rank : 130)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	267
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

M3K10_HUMAN
θ value	0.00102713 (rank : 288)	NC score	0.084287 (rank : 675)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1071	Shared Neighborhood Hits	196
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MAST1_MOUSE
θ value	0.00102713 (rank : 289)	NC score	0.066288 (rank : 844)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1123	Shared Neighborhood Hits	220
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NCOA6_HUMAN
θ value	0.00102713 (rank : 290)	NC score	0.122758 (rank : 521)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1202	Shared Neighborhood Hits	266
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

USH1G_HUMAN
θ value	0.00102713 (rank : 291)	NC score	0.645265 (rank : 145)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	250
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	0.00102713 (rank : 292)	NC score	0.645511 (rank : 144)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	251
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

APBA3_HUMAN
θ value	0.00134147 (rank : 293)	NC score	0.183258 (rank : 350)
Query Neighborhood Hits	1041	Target Neighborhood Hits	201	Shared Neighborhood Hits	133
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

DNMBP_HUMAN
θ value	0.00134147 (rank : 294)	NC score	0.182638 (rank : 353)
Query Neighborhood Hits	1041	Target Neighborhood Hits	413	Shared Neighborhood Hits	170
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

GABP3_MOUSE
θ value	0.00134147 (rank : 295)	NC score	0.718507 (rank : 65)
Query Neighborhood Hits	1041	Target Neighborhood Hits	330	Shared Neighborhood Hits	267
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

INADL_MOUSE
θ value	0.00134147 (rank : 296)	NC score	0.200664 (rank : 329)
Query Neighborhood Hits	1041	Target Neighborhood Hits	290	Shared Neighborhood Hits	153
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

ITSN1_HUMAN
θ value	0.00134147 (rank : 297)	NC score	0.162295 (rank : 407)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1757	Shared Neighborhood Hits	288
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_HUMAN
θ value	0.00134147 (rank : 298)	NC score	0.168596 (rank : 387)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1173	Shared Neighborhood Hits	220
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MTPN_MOUSE
θ value	0.00134147 (rank : 299)	NC score	0.706997 (rank : 85)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	255
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

NU214_HUMAN
θ value	0.00134147 (rank : 300)	NC score	0.126224 (rank : 507)
Query Neighborhood Hits	1041	Target Neighborhood Hits	657	Shared Neighborhood Hits	164
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

TEX14_MOUSE
θ value	0.00134147 (rank : 301)	NC score	0.381511 (rank : 259)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1333	Shared Neighborhood Hits	344
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

APBA1_HUMAN
θ value	0.00175202 (rank : 302)	NC score	0.178512 (rank : 361)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	149
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CDN2D_HUMAN
θ value	0.00175202 (rank : 303)	NC score	0.691274 (rank : 118)
Query Neighborhood Hits	1041	Target Neighborhood Hits	268	Shared Neighborhood Hits	254
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ITSN2_MOUSE
θ value	0.00175202 (rank : 304)	NC score	0.166090 (rank : 393)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1371	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LCP2_HUMAN
θ value	0.00175202 (rank : 305)	NC score	0.102614 (rank : 584)
Query Neighborhood Hits	1041	Target Neighborhood Hits	531	Shared Neighborhood Hits	142
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

M3K9_HUMAN
θ value	0.00175202 (rank : 306)	NC score	0.085154 (rank : 669)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1123	Shared Neighborhood Hits	205
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NCF1_MOUSE
θ value	0.00175202 (rank : 307)	NC score	0.186960 (rank : 347)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	121
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

RIMB1_MOUSE
θ value	0.00175202 (rank : 308)	NC score	0.105975 (rank : 569)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1376	Shared Neighborhood Hits	248
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ANR25_HUMAN
θ value	0.00228821 (rank : 309)	NC score	0.575158 (rank : 182)
Query Neighborhood Hits	1041	Target Neighborhood Hits	350	Shared Neighborhood Hits	266
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

APBA2_HUMAN
θ value	0.00228821 (rank : 310)	NC score	0.175173 (rank : 373)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	132
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.00228821 (rank : 311)	NC score	0.173980 (rank : 374)
Query Neighborhood Hits	1041	Target Neighborhood Hits	219	Shared Neighborhood Hits	133
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

DDFL1_HUMAN
θ value	0.00228821 (rank : 312)	NC score	0.343336 (rank : 265)
Query Neighborhood Hits	1041	Target Neighborhood Hits	353	Shared Neighborhood Hits	257
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FA47B_HUMAN
θ value	0.00228821 (rank : 313)	NC score	0.073691 (rank : 763)
Query Neighborhood Hits	1041	Target Neighborhood Hits	431	Shared Neighborhood Hits	112
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FAT2_HUMAN
θ value	0.00228821 (rank : 314)	NC score	0.024636 (rank : 1289)
Query Neighborhood Hits	1041	Target Neighborhood Hits	507	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

INADL_HUMAN
θ value	0.00228821 (rank : 315)	NC score	0.197289 (rank : 331)
Query Neighborhood Hits	1041	Target Neighborhood Hits	260	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

LIN7A_MOUSE
θ value	0.00228821 (rank : 316)	NC score	0.212559 (rank : 312)
Query Neighborhood Hits	1041	Target Neighborhood Hits	193	Shared Neighborhood Hits	138
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

MLL3_MOUSE
θ value	0.00228821 (rank : 317)	NC score	0.102220 (rank : 588)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1399	Shared Neighborhood Hits	245
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PLCG1_HUMAN
θ value	0.00228821 (rank : 318)	NC score	0.138016 (rank : 461)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	119
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SNTG1_MOUSE
θ value	0.00228821 (rank : 319)	NC score	0.175734 (rank : 371)
Query Neighborhood Hits	1041	Target Neighborhood Hits	179	Shared Neighborhood Hits	124
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ABL2_HUMAN
θ value	0.00298849 (rank : 320)	NC score	0.068367 (rank : 823)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1045	Shared Neighborhood Hits	155
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

AN30A_HUMAN
θ value	0.00298849 (rank : 321)	NC score	0.515531 (rank : 199)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1119	Shared Neighborhood Hits	324
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANS4B_HUMAN
θ value	0.00298849 (rank : 322)	NC score	0.643565 (rank : 146)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

CD2AP_MOUSE
θ value	0.00298849 (rank : 323)	NC score	0.216179 (rank : 308)
Query Neighborhood Hits	1041	Target Neighborhood Hits	336	Shared Neighborhood Hits	173
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

DDEF2_HUMAN
θ value	0.00298849 (rank : 324)	NC score	0.415637 (rank : 243)
Query Neighborhood Hits	1041	Target Neighborhood Hits	599	Shared Neighborhood Hits	401
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.00298849 (rank : 325)	NC score	0.412535 (rank : 245)
Query Neighborhood Hits	1041	Target Neighborhood Hits	625	Shared Neighborhood Hits	394
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

FGR_HUMAN
θ value	0.00298849 (rank : 326)	NC score	0.082612 (rank : 691)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1067	Shared Neighborhood Hits	181
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

LIPB1_HUMAN
θ value	0.00298849 (rank : 327)	NC score	0.085931 (rank : 667)
Query Neighborhood Hits	1041	Target Neighborhood Hits	640	Shared Neighborhood Hits	75
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

LIPB1_MOUSE
θ value	0.00298849 (rank : 328)	NC score	0.082306 (rank : 693)
Query Neighborhood Hits	1041	Target Neighborhood Hits	727	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

PLCG1_MOUSE
θ value	0.00298849 (rank : 329)	NC score	0.140185 (rank : 453)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	123
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SNTG1_HUMAN
θ value	0.00298849 (rank : 330)	NC score	0.175380 (rank : 372)
Query Neighborhood Hits	1041	Target Neighborhood Hits	181	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ANR33_MOUSE
θ value	0.00390308 (rank : 331)	NC score	0.591186 (rank : 172)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	218
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ASPP2_HUMAN
θ value	0.00390308 (rank : 332)	NC score	0.532007 (rank : 197)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1156	Shared Neighborhood Hits	465
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

GIT2_HUMAN
θ value	0.00390308 (rank : 333)	NC score	0.422891 (rank : 239)
Query Neighborhood Hits	1041	Target Neighborhood Hits	381	Shared Neighborhood Hits	256
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

LIN7B_HUMAN
θ value	0.00390308 (rank : 334)	NC score	0.211168 (rank : 317)
Query Neighborhood Hits	1041	Target Neighborhood Hits	200	Shared Neighborhood Hits	137
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
θ value	0.00390308 (rank : 335)	NC score	0.210102 (rank : 321)
Query Neighborhood Hits	1041	Target Neighborhood Hits	200	Shared Neighborhood Hits	137
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

PCLO_HUMAN
θ value	0.00390308 (rank : 336)	NC score	0.130386 (rank : 495)
Query Neighborhood Hits	1041	Target Neighborhood Hits	2046	Shared Neighborhood Hits	378
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RHPN1_MOUSE
θ value	0.00390308 (rank : 337)	NC score	0.162087 (rank : 410)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	110
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SRC8_MOUSE
θ value	0.00390308 (rank : 338)	NC score	0.176003 (rank : 369)
Query Neighborhood Hits	1041	Target Neighborhood Hits	292	Shared Neighborhood Hits	140
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

TCGAP_HUMAN
θ value	0.00390308 (rank : 339)	NC score	0.116086 (rank : 533)
Query Neighborhood Hits	1041	Target Neighborhood Hits	872	Shared Neighborhood Hits	269
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ARHG9_MOUSE
θ value	0.00509761 (rank : 340)	NC score	0.150535 (rank : 429)
Query Neighborhood Hits	1041	Target Neighborhood Hits	234	Shared Neighborhood Hits	133
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

BCAR1_HUMAN
θ value	0.00509761 (rank : 341)	NC score	0.141535 (rank : 450)
Query Neighborhood Hits	1041	Target Neighborhood Hits	554	Shared Neighborhood Hits	218
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CLPB_MOUSE
θ value	0.00509761 (rank : 342)	NC score	0.591140 (rank : 173)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	242
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CNKR2_HUMAN
θ value	0.00509761 (rank : 343)	NC score	0.127104 (rank : 504)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.00509761 (rank : 344)	NC score	0.127182 (rank : 503)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	84
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

MPP4_HUMAN
θ value	0.00509761 (rank : 345)	NC score	0.133916 (rank : 477)
Query Neighborhood Hits	1041	Target Neighborhood Hits	205	Shared Neighborhood Hits	147
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

OGFR_HUMAN
θ value	0.00509761 (rank : 346)	NC score	0.129770 (rank : 498)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1582	Shared Neighborhood Hits	318
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PDZD7_HUMAN
θ value	0.00509761 (rank : 347)	NC score	0.229874 (rank : 301)
Query Neighborhood Hits	1041	Target Neighborhood Hits	181	Shared Neighborhood Hits	137
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

APBA3_MOUSE
θ value	0.00665767 (rank : 348)	NC score	0.177637 (rank : 364)
Query Neighborhood Hits	1041	Target Neighborhood Hits	174	Shared Neighborhood Hits	125
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

FOG1_MOUSE
θ value	0.00665767 (rank : 349)	NC score	0.026538 (rank : 1279)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1237	Shared Neighborhood Hits	208
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GSCR1_HUMAN
θ value	0.00665767 (rank : 350)	NC score	0.170819 (rank : 382)
Query Neighborhood Hits	1041	Target Neighborhood Hits	674	Shared Neighborhood Hits	250
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SRC8_HUMAN
θ value	0.00665767 (rank : 351)	NC score	0.179365 (rank : 359)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	135
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

YES_MOUSE
θ value	0.00665767 (rank : 352)	NC score	0.080370 (rank : 714)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1052	Shared Neighborhood Hits	180
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ASPP1_HUMAN
θ value	0.00869519 (rank : 353)	NC score	0.545965 (rank : 192)
Query Neighborhood Hits	1041	Target Neighborhood Hits	956	Shared Neighborhood Hits	459
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	0.00869519 (rank : 354)	NC score	0.538186 (rank : 195)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1244	Shared Neighborhood Hits	514
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CO5A2_HUMAN
θ value	0.00869519 (rank : 355)	NC score	0.052600 (rank : 1069)
Query Neighborhood Hits	1041	Target Neighborhood Hits	760	Shared Neighborhood Hits	170
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

DNMBP_MOUSE
θ value	0.00869519 (rank : 356)	NC score	0.183445 (rank : 348)
Query Neighborhood Hits	1041	Target Neighborhood Hits	435	Shared Neighborhood Hits	177
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FOXE2_HUMAN
θ value	0.00869519 (rank : 357)	NC score	0.020039 (rank : 1320)
Query Neighborhood Hits	1041	Target Neighborhood Hits	236	Shared Neighborhood Hits	54
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

MYO1F_MOUSE
θ value	0.00869519 (rank : 358)	NC score	0.077388 (rank : 732)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	133
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NEB2_HUMAN
θ value	0.00869519 (rank : 359)	NC score	0.132187 (rank : 484)
Query Neighborhood Hits	1041	Target Neighborhood Hits	883	Shared Neighborhood Hits	173
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	0.00869519 (rank : 360)	NC score	0.130666 (rank : 493)
Query Neighborhood Hits	1041	Target Neighborhood Hits	889	Shared Neighborhood Hits	174
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NOXO1_HUMAN
θ value	0.00869519 (rank : 361)	NC score	0.125745 (rank : 511)
Query Neighborhood Hits	1041	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NUD12_HUMAN
θ value	0.00869519 (rank : 362)	NC score	0.455517 (rank : 229)
Query Neighborhood Hits	1041	Target Neighborhood Hits	222	Shared Neighborhood Hits	196
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

SAM14_HUMAN
θ value	0.00869519 (rank : 363)	NC score	0.131509 (rank : 486)
Query Neighborhood Hits	1041	Target Neighborhood Hits	81	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

TCGAP_MOUSE
θ value	0.00869519 (rank : 364)	NC score	0.101944 (rank : 590)
Query Neighborhood Hits	1041	Target Neighborhood Hits	409	Shared Neighborhood Hits	189
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ANR25_MOUSE
θ value	0.0113563 (rank : 365)	NC score	0.566239 (rank : 185)
Query Neighborhood Hits	1041	Target Neighborhood Hits	398	Shared Neighborhood Hits	281
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CD2AP_HUMAN
θ value	0.0113563 (rank : 366)	NC score	0.210399 (rank : 320)
Query Neighborhood Hits	1041	Target Neighborhood Hits	315	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CENG2_HUMAN
θ value	0.0113563 (rank : 367)	NC score	0.317274 (rank : 275)
Query Neighborhood Hits	1041	Target Neighborhood Hits	471	Shared Neighborhood Hits	250
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

GOGA3_HUMAN
θ value	0.0113563 (rank : 368)	NC score	0.052434 (rank : 1074)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1317	Shared Neighborhood Hits	124
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

IASPP_MOUSE
θ value	0.0113563 (rank : 369)	NC score	0.514294 (rank : 200)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1024	Shared Neighborhood Hits	500
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IKBL_HUMAN
θ value	0.0113563 (rank : 370)	NC score	0.328840 (rank : 272)
Query Neighborhood Hits	1041	Target Neighborhood Hits	168	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	0.0113563 (rank : 371)	NC score	0.322661 (rank : 273)
Query Neighborhood Hits	1041	Target Neighborhood Hits	196	Shared Neighborhood Hits	146
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

LIN7A_HUMAN
θ value	0.0113563 (rank : 372)	NC score	0.210632 (rank : 319)
Query Neighborhood Hits	1041	Target Neighborhood Hits	193	Shared Neighborhood Hits	138
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7C_HUMAN
θ value	0.0113563 (rank : 373)	NC score	0.207669 (rank : 325)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.0113563 (rank : 374)	NC score	0.207669 (rank : 326)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	137
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PZRN3_MOUSE
θ value	0.0113563 (rank : 375)	NC score	0.135916 (rank : 467)
Query Neighborhood Hits	1041	Target Neighborhood Hits	447	Shared Neighborhood Hits	138
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RPGF2_HUMAN
θ value	0.0113563 (rank : 376)	NC score	0.126386 (rank : 506)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

RPKL1_MOUSE
θ value	0.0113563 (rank : 377)	NC score	0.022878 (rank : 1303)
Query Neighborhood Hits	1041	Target Neighborhood Hits	704	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

ARHG9_HUMAN
θ value	0.0148317 (rank : 378)	NC score	0.149857 (rank : 430)
Query Neighborhood Hits	1041	Target Neighborhood Hits	235	Shared Neighborhood Hits	134
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

CENG1_HUMAN
θ value	0.0148317 (rank : 379)	NC score	0.333990 (rank : 270)
Query Neighborhood Hits	1041	Target Neighborhood Hits	544	Shared Neighborhood Hits	300
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	0.0148317 (rank : 380)	NC score	0.335905 (rank : 268)
Query Neighborhood Hits	1041	Target Neighborhood Hits	531	Shared Neighborhood Hits	300
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG2_MOUSE
θ value	0.0148317 (rank : 381)	NC score	0.314971 (rank : 276)
Query Neighborhood Hits	1041	Target Neighborhood Hits	463	Shared Neighborhood Hits	246
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DDFL1_MOUSE
θ value	0.0148317 (rank : 382)	NC score	0.411474 (rank : 246)
Query Neighborhood Hits	1041	Target Neighborhood Hits	324	Shared Neighborhood Hits	249
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DGKI_HUMAN
θ value	0.0148317 (rank : 383)	NC score	0.311899 (rank : 277)
Query Neighborhood Hits	1041	Target Neighborhood Hits	609	Shared Neighborhood Hits	220
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

GAB2_MOUSE
θ value	0.0148317 (rank : 384)	NC score	0.049728 (rank : 1135)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

HECD1_HUMAN
θ value	0.0148317 (rank : 385)	NC score	0.510905 (rank : 204)
Query Neighborhood Hits	1041	Target Neighborhood Hits	371	Shared Neighborhood Hits	265
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

LNX1_MOUSE
θ value	0.0148317 (rank : 386)	NC score	0.163899 (rank : 402)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	128
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

NOXO1_MOUSE
θ value	0.0148317 (rank : 387)	NC score	0.145956 (rank : 444)
Query Neighborhood Hits	1041	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

SPR1B_MOUSE
θ value	0.0148317 (rank : 388)	NC score	0.052727 (rank : 1065)
Query Neighborhood Hits	1041	Target Neighborhood Hits	395	Shared Neighborhood Hits	88
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

STAM1_MOUSE
θ value	0.0148317 (rank : 389)	NC score	0.167959 (rank : 389)
Query Neighborhood Hits	1041	Target Neighborhood Hits	273	Shared Neighborhood Hits	159
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TGON2_HUMAN
θ value	0.0148317 (rank : 390)	NC score	0.084916 (rank : 672)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1037	Shared Neighborhood Hits	196
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ZN334_HUMAN
θ value	0.0148317 (rank : 391)	NC score	-0.011709 (rank : 1477)
Query Neighborhood Hits	1041	Target Neighborhood Hits	778	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCZ1, Q5T6U2, Q9NVW4	Gene names	ZNF334
Domain Architecture
Description	Zinc finger protein 334.

ANR32_HUMAN
θ value	0.0193708 (rank : 392)	NC score	0.642246 (rank : 148)
Query Neighborhood Hits	1041	Target Neighborhood Hits	270	Shared Neighborhood Hits	249
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

GIT2_MOUSE
θ value	0.0193708 (rank : 393)	NC score	0.453691 (rank : 230)
Query Neighborhood Hits	1041	Target Neighborhood Hits	323	Shared Neighborhood Hits	254
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

MPP4_MOUSE
θ value	0.0193708 (rank : 394)	NC score	0.117175 (rank : 532)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	133
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

NUD12_MOUSE
θ value	0.0193708 (rank : 395)	NC score	0.481746 (rank : 215)
Query Neighborhood Hits	1041	Target Neighborhood Hits	243	Shared Neighborhood Hits	218
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

PZRN3_HUMAN
θ value	0.0193708 (rank : 396)	NC score	0.132592 (rank : 481)
Query Neighborhood Hits	1041	Target Neighborhood Hits	461	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RGS3_HUMAN
θ value	0.0193708 (rank : 397)	NC score	0.095315 (rank : 621)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1375	Shared Neighborhood Hits	271
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

YES_HUMAN
θ value	0.0193708 (rank : 398)	NC score	0.080452 (rank : 710)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1059	Shared Neighborhood Hits	185
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

CD248_HUMAN
θ value	0.0252991 (rank : 399)	NC score	0.064144 (rank : 863)
Query Neighborhood Hits	1041	Target Neighborhood Hits	679	Shared Neighborhood Hits	131
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MLL3_HUMAN
θ value	0.0252991 (rank : 400)	NC score	0.108027 (rank : 564)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1644	Shared Neighborhood Hits	281
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RPGF6_HUMAN
θ value	0.0252991 (rank : 401)	NC score	0.134014 (rank : 475)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SAMD9_HUMAN
θ value	0.0252991 (rank : 402)	NC score	0.080451 (rank : 711)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q5K651, Q6P080, Q75N21, Q8IVG6, Q9NXS8	Gene names	SAMD9, KIAA2004, OEF1
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 9.

SC24C_HUMAN
θ value	0.0252991 (rank : 403)	NC score	0.081910 (rank : 699)
Query Neighborhood Hits	1041	Target Neighborhood Hits	662	Shared Neighborhood Hits	158
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SNCAP_HUMAN
θ value	0.0252991 (rank : 404)	NC score	0.606934 (rank : 169)
Query Neighborhood Hits	1041	Target Neighborhood Hits	313	Shared Neighborhood Hits	241
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

STAM1_HUMAN
θ value	0.0252991 (rank : 405)	NC score	0.166079 (rank : 394)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	152
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ADA12_MOUSE
θ value	0.0330416 (rank : 406)	NC score	0.023372 (rank : 1300)
Query Neighborhood Hits	1041	Target Neighborhood Hits	474	Shared Neighborhood Hits	90
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

AFF3_HUMAN
θ value	0.0330416 (rank : 407)	NC score	0.038990 (rank : 1202)
Query Neighborhood Hits	1041	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

DGKZ_MOUSE
θ value	0.0330416 (rank : 408)	NC score	0.319571 (rank : 274)
Query Neighborhood Hits	1041	Target Neighborhood Hits	542	Shared Neighborhood Hits	207
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

KRIT1_HUMAN
θ value	0.0330416 (rank : 409)	NC score	0.559286 (rank : 188)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	218
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

NCF2_HUMAN
θ value	0.0330416 (rank : 410)	NC score	0.171335 (rank : 380)
Query Neighborhood Hits	1041	Target Neighborhood Hits	229	Shared Neighborhood Hits	135
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

RIMB2_MOUSE
θ value	0.0330416 (rank : 411)	NC score	0.123707 (rank : 517)
Query Neighborhood Hits	1041	Target Neighborhood Hits	246	Shared Neighborhood Hits	94
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SEZ6L_HUMAN
θ value	0.0330416 (rank : 412)	NC score	0.023706 (rank : 1295)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

T22D4_HUMAN
θ value	0.0330416 (rank : 413)	NC score	0.069206 (rank : 811)
Query Neighborhood Hits	1041	Target Neighborhood Hits	403	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

T22D4_MOUSE
θ value	0.0330416 (rank : 414)	NC score	0.054822 (rank : 1028)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	Q9EQN3	Gene names	Tsc22d4, Tilz2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2).

ABI2_HUMAN
θ value	0.0431538 (rank : 415)	NC score	0.187944 (rank : 346)
Query Neighborhood Hits	1041	Target Neighborhood Hits	350	Shared Neighborhood Hits	206
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	0.0431538 (rank : 416)	NC score	0.164541 (rank : 399)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	159
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ANKZ1_MOUSE
θ value	0.0431538 (rank : 417)	NC score	0.301515 (rank : 278)
Query Neighborhood Hits	1041	Target Neighborhood Hits	208	Shared Neighborhood Hits	158
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ANS4B_MOUSE
θ value	0.0431538 (rank : 418)	NC score	0.630249 (rank : 156)
Query Neighborhood Hits	1041	Target Neighborhood Hits	294	Shared Neighborhood Hits	248
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

CLPB_HUMAN
θ value	0.0431538 (rank : 419)	NC score	0.511091 (rank : 203)
Query Neighborhood Hits	1041	Target Neighborhood Hits	265	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

GRAP_HUMAN
θ value	0.0431538 (rank : 420)	NC score	0.178504 (rank : 362)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	155
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRIN1_HUMAN
θ value	0.0431538 (rank : 421)	NC score	0.092728 (rank : 635)
Query Neighborhood Hits	1041	Target Neighborhood Hits	681	Shared Neighborhood Hits	161
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MPDZ_HUMAN
θ value	0.0431538 (rank : 422)	NC score	0.193578 (rank : 337)
Query Neighborhood Hits	1041	Target Neighborhood Hits	261	Shared Neighborhood Hits	149
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PCLO_MOUSE
θ value	0.0431538 (rank : 423)	NC score	0.147838 (rank : 437)
Query Neighborhood Hits	1041	Target Neighborhood Hits	2275	Shared Neighborhood Hits	469
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDLI7_MOUSE
θ value	0.0431538 (rank : 424)	NC score	0.080372 (rank : 713)
Query Neighborhood Hits	1041	Target Neighborhood Hits	279	Shared Neighborhood Hits	103
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SRC_HUMAN
θ value	0.0431538 (rank : 425)	NC score	0.077891 (rank : 728)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1058	Shared Neighborhood Hits	183
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

ZIMP7_HUMAN
θ value	0.0431538 (rank : 426)	NC score	0.051703 (rank : 1093)
Query Neighborhood Hits	1041	Target Neighborhood Hits	290	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIMP7_MOUSE
θ value	0.0431538 (rank : 427)	NC score	0.063669 (rank : 870)
Query Neighborhood Hits	1041	Target Neighborhood Hits	566	Shared Neighborhood Hits	136
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ACK1_HUMAN
θ value	0.0563607 (rank : 428)	NC score	0.059719 (rank : 945)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1140	Shared Neighborhood Hits	214
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ANM2_HUMAN
θ value	0.0563607 (rank : 429)	NC score	0.101416 (rank : 592)
Query Neighborhood Hits	1041	Target Neighborhood Hits	175	Shared Neighborhood Hits	108
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

CTND2_HUMAN
θ value	0.0563607 (rank : 430)	NC score	0.034333 (rank : 1231)
Query Neighborhood Hits	1041	Target Neighborhood Hits	333	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DACT1_HUMAN
θ value	0.0563607 (rank : 431)	NC score	0.047725 (rank : 1149)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

DOK7_MOUSE
θ value	0.0563607 (rank : 432)	NC score	0.043042 (rank : 1178)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	45
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

EPN3_MOUSE
θ value	0.0563607 (rank : 433)	NC score	0.057510 (rank : 983)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	94
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

HCLS1_MOUSE
θ value	0.0563607 (rank : 434)	NC score	0.178177 (rank : 363)
Query Neighborhood Hits	1041	Target Neighborhood Hits	329	Shared Neighborhood Hits	161
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HXA3_HUMAN
θ value	0.0563607 (rank : 435)	NC score	0.028510 (rank : 1265)
Query Neighborhood Hits	1041	Target Neighborhood Hits	535	Shared Neighborhood Hits	129
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

HXB3_MOUSE
θ value	0.0563607 (rank : 436)	NC score	0.011977 (rank : 1355)
Query Neighborhood Hits	1041	Target Neighborhood Hits	493	Shared Neighborhood Hits	59
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

MPDZ_MOUSE
θ value	0.0563607 (rank : 437)	NC score	0.194368 (rank : 336)
Query Neighborhood Hits	1041	Target Neighborhood Hits	298	Shared Neighborhood Hits	156
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MYO1F_HUMAN
θ value	0.0563607 (rank : 438)	NC score	0.079075 (rank : 721)
Query Neighborhood Hits	1041	Target Neighborhood Hits	275	Shared Neighborhood Hits	146
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

SAM14_MOUSE
θ value	0.0563607 (rank : 439)	NC score	0.120326 (rank : 526)
Query Neighborhood Hits	1041	Target Neighborhood Hits	91	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SDCB2_MOUSE
θ value	0.0563607 (rank : 440)	NC score	0.138259 (rank : 460)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	92
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SH3G2_HUMAN
θ value	0.0563607 (rank : 441)	NC score	0.147972 (rank : 436)
Query Neighborhood Hits	1041	Target Neighborhood Hits	324	Shared Neighborhood Hits	137
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

STAC_HUMAN
θ value	0.0563607 (rank : 442)	NC score	0.171958 (rank : 379)
Query Neighborhood Hits	1041	Target Neighborhood Hits	276	Shared Neighborhood Hits	139
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ZN516_MOUSE
θ value	0.0563607 (rank : 443)	NC score	0.005891 (rank : 1406)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1197	Shared Neighborhood Hits	160
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZSCA5_HUMAN
θ value	0.0563607 (rank : 444)	NC score	-0.008687 (rank : 1468)
Query Neighborhood Hits	1041	Target Neighborhood Hits	862	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

ANR33_HUMAN
θ value	0.0736092 (rank : 445)	NC score	0.577550 (rank : 181)
Query Neighborhood Hits	1041	Target Neighborhood Hits	215	Shared Neighborhood Hits	211
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

BAT2_HUMAN
θ value	0.0736092 (rank : 446)	NC score	0.149159 (rank : 433)
Query Neighborhood Hits	1041	Target Neighborhood Hits	931	Shared Neighborhood Hits	280
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CENB1_HUMAN
θ value	0.0736092 (rank : 447)	NC score	0.478256 (rank : 217)
Query Neighborhood Hits	1041	Target Neighborhood Hits	383	Shared Neighborhood Hits	265
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DLG2_HUMAN
θ value	0.0736092 (rank : 448)	NC score	0.163840 (rank : 403)
Query Neighborhood Hits	1041	Target Neighborhood Hits	279	Shared Neighborhood Hits	180
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

GRIP2_HUMAN
θ value	0.0736092 (rank : 449)	NC score	0.182872 (rank : 352)
Query Neighborhood Hits	1041	Target Neighborhood Hits	256	Shared Neighborhood Hits	149
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

LIPB2_HUMAN
θ value	0.0736092 (rank : 450)	NC score	0.086476 (rank : 662)
Query Neighborhood Hits	1041	Target Neighborhood Hits	599	Shared Neighborhood Hits	75
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LIPB2_MOUSE
θ value	0.0736092 (rank : 451)	NC score	0.091910 (rank : 641)
Query Neighborhood Hits	1041	Target Neighborhood Hits	570	Shared Neighborhood Hits	86
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

LNX2_HUMAN
θ value	0.0736092 (rank : 452)	NC score	0.153326 (rank : 422)
Query Neighborhood Hits	1041	Target Neighborhood Hits	389	Shared Neighborhood Hits	136
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MYO1E_HUMAN
θ value	0.0736092 (rank : 453)	NC score	0.078392 (rank : 726)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	138
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

NCOR2_HUMAN
θ value	0.0736092 (rank : 454)	NC score	0.095766 (rank : 618)
Query Neighborhood Hits	1041	Target Neighborhood Hits	870	Shared Neighborhood Hits	217
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NPHP1_HUMAN
θ value	0.0736092 (rank : 455)	NC score	0.109014 (rank : 561)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	112
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NRX2A_HUMAN
θ value	0.0736092 (rank : 456)	NC score	0.047394 (rank : 1151)
Query Neighborhood Hits	1041	Target Neighborhood Hits	614	Shared Neighborhood Hits	118
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.0736092 (rank : 457)	NC score	0.045657 (rank : 1158)
Query Neighborhood Hits	1041	Target Neighborhood Hits	481	Shared Neighborhood Hits	103
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PAR3L_HUMAN
θ value	0.0736092 (rank : 458)	NC score	0.169387 (rank : 386)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	135
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDLI5_MOUSE
θ value	0.0736092 (rank : 459)	NC score	0.083972 (rank : 678)
Query Neighborhood Hits	1041	Target Neighborhood Hits	287	Shared Neighborhood Hits	121
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PGCA_HUMAN
θ value	0.0736092 (rank : 460)	NC score	0.059174 (rank : 955)
Query Neighborhood Hits	1041	Target Neighborhood Hits	821	Shared Neighborhood Hits	126
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PSL1_HUMAN
θ value	0.0736092 (rank : 461)	NC score	0.055760 (rank : 1014)
Query Neighborhood Hits	1041	Target Neighborhood Hits	650	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SAPS1_HUMAN
θ value	0.0736092 (rank : 462)	NC score	0.078339 (rank : 727)
Query Neighborhood Hits	1041	Target Neighborhood Hits	704	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SDCB1_MOUSE
θ value	0.0736092 (rank : 463)	NC score	0.146302 (rank : 442)
Query Neighborhood Hits	1041	Target Neighborhood Hits	144	Shared Neighborhood Hits	116
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SH3G2_MOUSE
θ value	0.0736092 (rank : 464)	NC score	0.146861 (rank : 440)
Query Neighborhood Hits	1041	Target Neighborhood Hits	319	Shared Neighborhood Hits	135
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SYNJ1_MOUSE
θ value	0.0736092 (rank : 465)	NC score	0.078967 (rank : 722)
Query Neighborhood Hits	1041	Target Neighborhood Hits	516	Shared Neighborhood Hits	187
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYP2L_HUMAN
θ value	0.0736092 (rank : 466)	NC score	0.189159 (rank : 344)
Query Neighborhood Hits	1041	Target Neighborhood Hits	400	Shared Neighborhood Hits	222
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CIC_HUMAN
θ value	0.0961366 (rank : 467)	NC score	0.104568 (rank : 576)
Query Neighborhood Hits	1041	Target Neighborhood Hits	992	Shared Neighborhood Hits	269
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HDAC5_HUMAN
θ value	0.0961366 (rank : 468)	NC score	0.024108 (rank : 1293)
Query Neighborhood Hits	1041	Target Neighborhood Hits	353	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

K1802_HUMAN
θ value	0.0961366 (rank : 469)	NC score	0.082748 (rank : 689)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1378	Shared Neighborhood Hits	253
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1849_HUMAN
θ value	0.0961366 (rank : 470)	NC score	0.144534 (rank : 446)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	128
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MUCDL_HUMAN
θ value	0.0961366 (rank : 471)	NC score	0.090747 (rank : 646)
Query Neighborhood Hits	1041	Target Neighborhood Hits	777	Shared Neighborhood Hits	195
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RHPN1_HUMAN
θ value	0.0961366 (rank : 472)	NC score	0.136952 (rank : 464)
Query Neighborhood Hits	1041	Target Neighborhood Hits	158	Shared Neighborhood Hits	109
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SDCB2_HUMAN
θ value	0.0961366 (rank : 473)	NC score	0.132345 (rank : 482)
Query Neighborhood Hits	1041	Target Neighborhood Hits	121	Shared Neighborhood Hits	99
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

TACC3_HUMAN
θ value	0.0961366 (rank : 474)	NC score	0.063366 (rank : 874)
Query Neighborhood Hits	1041	Target Neighborhood Hits	779	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TX1B3_HUMAN
θ value	0.0961366 (rank : 475)	NC score	0.196206 (rank : 332)
Query Neighborhood Hits	1041	Target Neighborhood Hits	161	Shared Neighborhood Hits	123
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.0961366 (rank : 476)	NC score	0.194443 (rank : 335)
Query Neighborhood Hits	1041	Target Neighborhood Hits	158	Shared Neighborhood Hits	120
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

ANM2_MOUSE
θ value	0.125558 (rank : 477)	NC score	0.094154 (rank : 626)
Query Neighborhood Hits	1041	Target Neighborhood Hits	175	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

DGKZ_HUMAN
θ value	0.125558 (rank : 478)	NC score	0.334014 (rank : 269)
Query Neighborhood Hits	1041	Target Neighborhood Hits	551	Shared Neighborhood Hits	219
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

EGR4_HUMAN
θ value	0.125558 (rank : 479)	NC score	-0.005627 (rank : 1463)
Query Neighborhood Hits	1041	Target Neighborhood Hits	939	Shared Neighborhood Hits	88
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

FOXN1_HUMAN
θ value	0.125558 (rank : 480)	NC score	0.023387 (rank : 1299)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	86
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GRAP_MOUSE
θ value	0.125558 (rank : 481)	NC score	0.179879 (rank : 358)
Query Neighborhood Hits	1041	Target Neighborhood Hits	309	Shared Neighborhood Hits	153
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRIP1_HUMAN
θ value	0.125558 (rank : 482)	NC score	0.179341 (rank : 360)
Query Neighborhood Hits	1041	Target Neighborhood Hits	231	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
θ value	0.125558 (rank : 483)	NC score	0.176341 (rank : 368)
Query Neighborhood Hits	1041	Target Neighborhood Hits	241	Shared Neighborhood Hits	144
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

IASPP_HUMAN
θ value	0.125558 (rank : 484)	NC score	0.558239 (rank : 189)
Query Neighborhood Hits	1041	Target Neighborhood Hits	688	Shared Neighborhood Hits	460
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KRIT1_MOUSE
θ value	0.125558 (rank : 485)	NC score	0.564753 (rank : 186)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	224
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

LPP_HUMAN
θ value	0.125558 (rank : 486)	NC score	0.056367 (rank : 1003)
Query Neighborhood Hits	1041	Target Neighborhood Hits	775	Shared Neighborhood Hits	162
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MLTK_HUMAN
θ value	0.125558 (rank : 487)	NC score	0.055237 (rank : 1024)
Query Neighborhood Hits	1041	Target Neighborhood Hits	911	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	0.125558 (rank : 488)	NC score	0.054805 (rank : 1029)
Query Neighborhood Hits	1041	Target Neighborhood Hits	874	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

SRRM2_HUMAN
θ value	0.125558 (rank : 489)	NC score	0.149055 (rank : 434)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1296	Shared Neighborhood Hits	304
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ULK1_HUMAN
θ value	0.125558 (rank : 490)	NC score	0.036866 (rank : 1219)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1121	Shared Neighborhood Hits	158
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ANR32_MOUSE
θ value	0.163984 (rank : 491)	NC score	0.632540 (rank : 155)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	250
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR38_MOUSE
θ value	0.163984 (rank : 492)	NC score	0.541622 (rank : 194)
Query Neighborhood Hits	1041	Target Neighborhood Hits	512	Shared Neighborhood Hits	264
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR40_HUMAN
θ value	0.163984 (rank : 493)	NC score	0.515730 (rank : 198)
Query Neighborhood Hits	1041	Target Neighborhood Hits	224	Shared Neighborhood Hits	211
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

BAT2_MOUSE
θ value	0.163984 (rank : 494)	NC score	0.123115 (rank : 520)
Query Neighborhood Hits	1041	Target Neighborhood Hits	947	Shared Neighborhood Hits	265
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EFS_HUMAN
θ value	0.163984 (rank : 495)	NC score	0.131329 (rank : 489)
Query Neighborhood Hits	1041	Target Neighborhood Hits	348	Shared Neighborhood Hits	180
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

MAP1A_HUMAN
θ value	0.163984 (rank : 496)	NC score	0.073568 (rank : 764)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1626	Shared Neighborhood Hits	227
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MORC2_HUMAN
θ value	0.163984 (rank : 497)	NC score	0.035958 (rank : 1226)
Query Neighborhood Hits	1041	Target Neighborhood Hits	207	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

SARM1_MOUSE
θ value	0.163984 (rank : 498)	NC score	0.086067 (rank : 666)
Query Neighborhood Hits	1041	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

SNTG2_HUMAN
θ value	0.163984 (rank : 499)	NC score	0.170087 (rank : 384)
Query Neighborhood Hits	1041	Target Neighborhood Hits	191	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG2_MOUSE
θ value	0.163984 (rank : 500)	NC score	0.156407 (rank : 418)
Query Neighborhood Hits	1041	Target Neighborhood Hits	176	Shared Neighborhood Hits	122
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

STAC_MOUSE
θ value	0.163984 (rank : 501)	NC score	0.172970 (rank : 377)
Query Neighborhood Hits	1041	Target Neighborhood Hits	268	Shared Neighborhood Hits	140
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TULP4_HUMAN
θ value	0.163984 (rank : 502)	NC score	0.040892 (rank : 1190)
Query Neighborhood Hits	1041	Target Neighborhood Hits	426	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ARI1A_HUMAN
θ value	0.21417 (rank : 503)	NC score	0.099314 (rank : 601)
Query Neighborhood Hits	1041	Target Neighborhood Hits	787	Shared Neighborhood Hits	218
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ARMX2_MOUSE
θ value	0.21417 (rank : 504)	NC score	0.048597 (rank : 1142)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	94
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

EPHB1_HUMAN
θ value	0.21417 (rank : 505)	NC score	0.047248 (rank : 1152)
Query Neighborhood Hits	1041	Target Neighborhood Hits	988	Shared Neighborhood Hits	88
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

FGR_MOUSE
θ value	0.21417 (rank : 506)	NC score	0.079599 (rank : 716)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1069	Shared Neighborhood Hits	185
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

HDAC5_MOUSE
θ value	0.21417 (rank : 507)	NC score	0.021398 (rank : 1314)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

LRP11_HUMAN
θ value	0.21417 (rank : 508)	NC score	0.018360 (rank : 1327)
Query Neighborhood Hits	1041	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

MDC1_MOUSE
θ value	0.21417 (rank : 509)	NC score	0.113289 (rank : 542)
Query Neighborhood Hits	1041	Target Neighborhood Hits	998	Shared Neighborhood Hits	237
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

OGFR_MOUSE
θ value	0.21417 (rank : 510)	NC score	0.069205 (rank : 812)
Query Neighborhood Hits	1041	Target Neighborhood Hits	584	Shared Neighborhood Hits	123
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PDLI2_MOUSE
θ value	0.21417 (rank : 511)	NC score	0.125357 (rank : 512)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	111
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

RECQ5_HUMAN
θ value	0.21417 (rank : 512)	NC score	0.029293 (rank : 1261)
Query Neighborhood Hits	1041	Target Neighborhood Hits	390	Shared Neighborhood Hits	96
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SPR1A_MOUSE
θ value	0.21417 (rank : 513)	NC score	0.047739 (rank : 1148)
Query Neighborhood Hits	1041	Target Neighborhood Hits	343	Shared Neighborhood Hits	70
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

STAC3_HUMAN
θ value	0.21417 (rank : 514)	NC score	0.149718 (rank : 432)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	119
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	0.21417 (rank : 515)	NC score	0.151850 (rank : 427)
Query Neighborhood Hits	1041	Target Neighborhood Hits	232	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

ABTB2_HUMAN
θ value	0.279714 (rank : 516)	NC score	0.479541 (rank : 216)
Query Neighborhood Hits	1041	Target Neighborhood Hits	391	Shared Neighborhood Hits	230
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

BAG3_MOUSE
θ value	0.279714 (rank : 517)	NC score	0.092949 (rank : 632)
Query Neighborhood Hits	1041	Target Neighborhood Hits	513	Shared Neighborhood Hits	151
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CAC1G_HUMAN
θ value	0.279714 (rank : 518)	NC score	0.029709 (rank : 1257)
Query Neighborhood Hits	1041	Target Neighborhood Hits	587	Shared Neighborhood Hits	131
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CO4A3_HUMAN
θ value	0.279714 (rank : 519)	NC score	0.038802 (rank : 1205)
Query Neighborhood Hits	1041	Target Neighborhood Hits	421	Shared Neighborhood Hits	120
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CSF1_HUMAN
θ value	0.279714 (rank : 520)	NC score	0.072182 (rank : 779)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	82
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CSTF2_HUMAN
θ value	0.279714 (rank : 521)	NC score	0.011298 (rank : 1358)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	34
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

DUET_HUMAN
θ value	0.279714 (rank : 522)	NC score	0.045232 (rank : 1162)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1220	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

HCLS1_HUMAN
θ value	0.279714 (rank : 523)	NC score	0.176344 (rank : 367)
Query Neighborhood Hits	1041	Target Neighborhood Hits	358	Shared Neighborhood Hits	171
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

MYLK_MOUSE
θ value	0.279714 (rank : 524)	NC score	0.032166 (rank : 1247)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1489	Shared Neighborhood Hits	154
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

TARA_HUMAN
θ value	0.279714 (rank : 525)	NC score	0.095937 (rank : 617)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1626	Shared Neighborhood Hits	276
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TIAM1_HUMAN
θ value	0.279714 (rank : 526)	NC score	0.118145 (rank : 529)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	97
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ANR22_HUMAN
θ value	0.365318 (rank : 527)	NC score	0.687059 (rank : 123)
Query Neighborhood Hits	1041	Target Neighborhood Hits	243	Shared Neighborhood Hits	238
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR40_MOUSE
θ value	0.365318 (rank : 528)	NC score	0.511305 (rank : 202)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	217
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ARHG5_HUMAN
θ value	0.365318 (rank : 529)	NC score	0.097203 (rank : 613)
Query Neighborhood Hits	1041	Target Neighborhood Hits	172	Shared Neighborhood Hits	86
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ASXL1_MOUSE
θ value	0.365318 (rank : 530)	NC score	0.027236 (rank : 1275)
Query Neighborhood Hits	1041	Target Neighborhood Hits	182	Shared Neighborhood Hits	39
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CO039_MOUSE
θ value	0.365318 (rank : 531)	NC score	0.078625 (rank : 724)
Query Neighborhood Hits	1041	Target Neighborhood Hits	445	Shared Neighborhood Hits	142
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CRK_MOUSE
θ value	0.365318 (rank : 532)	NC score	0.149720 (rank : 431)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	146
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

DIDO1_HUMAN
θ value	0.365318 (rank : 533)	NC score	0.070140 (rank : 802)
Query Neighborhood Hits	1041	Target Neighborhood Hits	960	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DLG5_HUMAN
θ value	0.365318 (rank : 534)	NC score	0.130146 (rank : 497)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1088	Shared Neighborhood Hits	240
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

EM55_HUMAN
θ value	0.365318 (rank : 535)	NC score	0.109951 (rank : 556)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	169
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

GAB2_HUMAN
θ value	0.365318 (rank : 536)	NC score	0.042969 (rank : 1180)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GGA1_HUMAN
θ value	0.365318 (rank : 537)	NC score	0.024638 (rank : 1288)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GRB2_HUMAN
θ value	0.365318 (rank : 538)	NC score	0.176583 (rank : 365)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	148
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.365318 (rank : 539)	NC score	0.176501 (rank : 366)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	148
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

MKL1_MOUSE
θ value	0.365318 (rank : 540)	NC score	0.054657 (rank : 1035)
Query Neighborhood Hits	1041	Target Neighborhood Hits	667	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PDLI7_HUMAN
θ value	0.365318 (rank : 541)	NC score	0.086220 (rank : 664)
Query Neighborhood Hits	1041	Target Neighborhood Hits	547	Shared Neighborhood Hits	173
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SARM1_HUMAN
θ value	0.365318 (rank : 542)	NC score	0.079359 (rank : 719)
Query Neighborhood Hits	1041	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

SNTB2_HUMAN
θ value	0.365318 (rank : 543)	NC score	0.147825 (rank : 438)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	125
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	0.365318 (rank : 544)	NC score	0.147305 (rank : 439)
Query Neighborhood Hits	1041	Target Neighborhood Hits	181	Shared Neighborhood Hits	123
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SOX13_MOUSE
θ value	0.365318 (rank : 545)	NC score	0.029270 (rank : 1262)
Query Neighborhood Hits	1041	Target Neighborhood Hits	495	Shared Neighborhood Hits	94
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SRC_MOUSE
θ value	0.365318 (rank : 546)	NC score	0.070734 (rank : 796)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1033	Shared Neighborhood Hits	163
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

TXND2_HUMAN
θ value	0.365318 (rank : 547)	NC score	0.085068 (rank : 670)
Query Neighborhood Hits	1041	Target Neighborhood Hits	793	Shared Neighborhood Hits	149
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

VINEX_MOUSE
θ value	0.365318 (rank : 548)	NC score	0.163418 (rank : 404)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ZBTB3_HUMAN
θ value	0.365318 (rank : 549)	NC score	-0.001573 (rank : 1449)
Query Neighborhood Hits	1041	Target Neighborhood Hits	910	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ZN687_HUMAN
θ value	0.365318 (rank : 550)	NC score	0.015756 (rank : 1343)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1244	Shared Neighborhood Hits	174
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AN13A_HUMAN
θ value	0.47712 (rank : 551)	NC score	0.394703 (rank : 251)
Query Neighborhood Hits	1041	Target Neighborhood Hits	243	Shared Neighborhood Hits	214
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANR37_HUMAN
θ value	0.47712 (rank : 552)	NC score	0.614875 (rank : 165)
Query Neighborhood Hits	1041	Target Neighborhood Hits	247	Shared Neighborhood Hits	242
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

APXL_HUMAN
θ value	0.47712 (rank : 553)	NC score	0.118607 (rank : 528)
Query Neighborhood Hits	1041	Target Neighborhood Hits	553	Shared Neighborhood Hits	158
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BIN1_MOUSE
θ value	0.47712 (rank : 554)	NC score	0.068947 (rank : 816)
Query Neighborhood Hits	1041	Target Neighborhood Hits	283	Shared Neighborhood Hits	118
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CBP_MOUSE
θ value	0.47712 (rank : 555)	NC score	0.095121 (rank : 622)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1051	Shared Neighborhood Hits	256
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CENG3_HUMAN
θ value	0.47712 (rank : 556)	NC score	0.291154 (rank : 280)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	235
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.47712 (rank : 557)	NC score	0.291201 (rank : 279)
Query Neighborhood Hits	1041	Target Neighborhood Hits	467	Shared Neighborhood Hits	235
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CYTSA_HUMAN
θ value	0.47712 (rank : 558)	NC score	0.043853 (rank : 1172)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1138	Shared Neighborhood Hits	118
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DAB2P_HUMAN
θ value	0.47712 (rank : 559)	NC score	0.021504 (rank : 1312)
Query Neighborhood Hits	1041	Target Neighborhood Hits	303	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

EPHA5_HUMAN
θ value	0.47712 (rank : 560)	NC score	0.051320 (rank : 1102)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1009	Shared Neighborhood Hits	95
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

GA2L2_MOUSE
θ value	0.47712 (rank : 561)	NC score	0.044595 (rank : 1166)
Query Neighborhood Hits	1041	Target Neighborhood Hits	395	Shared Neighborhood Hits	101
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GRAP2_MOUSE
θ value	0.47712 (rank : 562)	NC score	0.162752 (rank : 406)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	145
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

IF4G1_MOUSE
θ value	0.47712 (rank : 563)	NC score	0.056671 (rank : 1000)
Query Neighborhood Hits	1041	Target Neighborhood Hits	534	Shared Neighborhood Hits	142
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K1683_HUMAN
θ value	0.47712 (rank : 564)	NC score	0.062246 (rank : 897)
Query Neighborhood Hits	1041	Target Neighborhood Hits	240	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

K1849_MOUSE
θ value	0.47712 (rank : 565)	NC score	0.135005 (rank : 471)
Query Neighborhood Hits	1041	Target Neighborhood Hits	335	Shared Neighborhood Hits	150
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

KCNB1_MOUSE
θ value	0.47712 (rank : 566)	NC score	0.000918 (rank : 1436)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

MEF2B_MOUSE
θ value	0.47712 (rank : 567)	NC score	0.032905 (rank : 1243)
Query Neighborhood Hits	1041	Target Neighborhood Hits	218	Shared Neighborhood Hits	51
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MLL2_HUMAN
θ value	0.47712 (rank : 568)	NC score	0.126057 (rank : 509)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1788	Shared Neighborhood Hits	359
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYO15_MOUSE
θ value	0.47712 (rank : 569)	NC score	0.038551 (rank : 1206)
Query Neighborhood Hits	1041	Target Neighborhood Hits	467	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PGCA_MOUSE
θ value	0.47712 (rank : 570)	NC score	0.027872 (rank : 1269)
Query Neighborhood Hits	1041	Target Neighborhood Hits	643	Shared Neighborhood Hits	99
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PRGR_MOUSE
θ value	0.47712 (rank : 571)	NC score	0.018647 (rank : 1326)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	52
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

RIMB2_HUMAN
θ value	0.47712 (rank : 572)	NC score	0.123554 (rank : 518)
Query Neighborhood Hits	1041	Target Neighborhood Hits	263	Shared Neighborhood Hits	106
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

STAM2_HUMAN
θ value	0.47712 (rank : 573)	NC score	0.154849 (rank : 420)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	150
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STRAD_MOUSE
θ value	0.47712 (rank : 574)	NC score	0.043854 (rank : 1171)
Query Neighborhood Hits	1041	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q60924	Gene names	Stra13
Domain Architecture	No domain graphic available
Description	Retinoic acid-inducible E3 protein (Hematopoietic-specific protein E3).

TENS4_HUMAN
θ value	0.47712 (rank : 575)	NC score	0.042426 (rank : 1181)
Query Neighborhood Hits	1041	Target Neighborhood Hits	214	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

ZBT16_HUMAN
θ value	0.47712 (rank : 576)	NC score	-0.010999 (rank : 1474)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1010	Shared Neighborhood Hits	81
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZN385_HUMAN
θ value	0.47712 (rank : 577)	NC score	0.059684 (rank : 948)
Query Neighborhood Hits	1041	Target Neighborhood Hits	614	Shared Neighborhood Hits	121
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZN409_HUMAN
θ value	0.47712 (rank : 578)	NC score	0.019907 (rank : 1321)
Query Neighborhood Hits	1041	Target Neighborhood Hits	842	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

ZN710_HUMAN
θ value	0.47712 (rank : 579)	NC score	-0.011748 (rank : 1478)
Query Neighborhood Hits	1041	Target Neighborhood Hits	796	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ADA19_HUMAN
θ value	0.62314 (rank : 580)	NC score	0.020188 (rank : 1319)
Query Neighborhood Hits	1041	Target Neighborhood Hits	381	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADDB_MOUSE
θ value	0.62314 (rank : 581)	NC score	0.035415 (rank : 1229)
Query Neighborhood Hits	1041	Target Neighborhood Hits	574	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AN13A_MOUSE
θ value	0.62314 (rank : 582)	NC score	0.372348 (rank : 261)
Query Neighborhood Hits	1041	Target Neighborhood Hits	226	Shared Neighborhood Hits	213
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

APEX2_HUMAN
θ value	0.62314 (rank : 583)	NC score	0.018076 (rank : 1329)
Query Neighborhood Hits	1041	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

CRKL_HUMAN
θ value	0.62314 (rank : 584)	NC score	0.152502 (rank : 424)
Query Neighborhood Hits	1041	Target Neighborhood Hits	313	Shared Neighborhood Hits	148
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	0.62314 (rank : 585)	NC score	0.150967 (rank : 428)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	143
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CSPG5_HUMAN
θ value	0.62314 (rank : 586)	NC score	0.043932 (rank : 1170)
Query Neighborhood Hits	1041	Target Neighborhood Hits	199	Shared Neighborhood Hits	62
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CT012_MOUSE
θ value	0.62314 (rank : 587)	NC score	0.384173 (rank : 257)
Query Neighborhood Hits	1041	Target Neighborhood Hits	229	Shared Neighborhood Hits	177
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

CTDP1_HUMAN
θ value	0.62314 (rank : 588)	NC score	0.069497 (rank : 808)
Query Neighborhood Hits	1041	Target Neighborhood Hits	416	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DRD2_MOUSE
θ value	0.62314 (rank : 589)	NC score	-0.011450 (rank : 1476)
Query Neighborhood Hits	1041	Target Neighborhood Hits	779	Shared Neighborhood Hits	12
SwissProt Accessions	P61168, P13953	Gene names	Drd2
Domain Architecture
Description	D(2) dopamine receptor (Dopamine D2 receptor).

EPN3_HUMAN
θ value	0.62314 (rank : 590)	NC score	0.040049 (rank : 1193)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

LMBL3_HUMAN
θ value	0.62314 (rank : 591)	NC score	0.024665 (rank : 1287)
Query Neighborhood Hits	1041	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	Q96JM7, Q5VUM9, Q6P9B5	Gene names	L3MBTL3, KIAA1798
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein) (H-l(3)mbt-like protein).

NGEF_MOUSE
θ value	0.62314 (rank : 592)	NC score	0.097994 (rank : 609)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NOS1_HUMAN
θ value	0.62314 (rank : 593)	NC score	0.073109 (rank : 771)
Query Neighborhood Hits	1041	Target Neighborhood Hits	218	Shared Neighborhood Hits	121
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PARD3_HUMAN
θ value	0.62314 (rank : 594)	NC score	0.173822 (rank : 375)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PEX14_MOUSE
θ value	0.62314 (rank : 595)	NC score	0.024814 (rank : 1286)
Query Neighborhood Hits	1041	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

PHLB1_HUMAN
θ value	0.62314 (rank : 596)	NC score	0.067692 (rank : 830)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1038	Shared Neighborhood Hits	173
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA6_HUMAN
θ value	0.62314 (rank : 597)	NC score	0.048570 (rank : 1143)
Query Neighborhood Hits	1041	Target Neighborhood Hits	556	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PRR3_HUMAN
θ value	0.62314 (rank : 598)	NC score	0.030585 (rank : 1252)
Query Neighborhood Hits	1041	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	P79522, Q5RJB5	Gene names	PRR3, CAT56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

RTP3_MOUSE
θ value	0.62314 (rank : 599)	NC score	0.075656 (rank : 747)
Query Neighborhood Hits	1041	Target Neighborhood Hits	374	Shared Neighborhood Hits	106
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SDCB1_HUMAN
θ value	0.62314 (rank : 600)	NC score	0.137140 (rank : 462)
Query Neighborhood Hits	1041	Target Neighborhood Hits	150	Shared Neighborhood Hits	120
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

STAM2_MOUSE
θ value	0.62314 (rank : 601)	NC score	0.157157 (rank : 417)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	147
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TRIPB_HUMAN
θ value	0.62314 (rank : 602)	NC score	0.050478 (rank : 1121)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1587	Shared Neighborhood Hits	137
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ABTB2_MOUSE
θ value	0.813845 (rank : 603)	NC score	0.468355 (rank : 221)
Query Neighborhood Hits	1041	Target Neighborhood Hits	414	Shared Neighborhood Hits	229
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ADA1D_MOUSE
θ value	0.813845 (rank : 604)	NC score	-0.015528 (rank : 1485)
Query Neighborhood Hits	1041	Target Neighborhood Hits	874	Shared Neighborhood Hits	7
SwissProt Accessions	P97714, Q61619	Gene names	Adra1d, Adra1a, Gpcr8
Domain Architecture
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D- adrenoreceptor) (Alpha-1A adrenergic receptor).

AMPH_MOUSE
θ value	0.813845 (rank : 605)	NC score	0.080737 (rank : 708)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	108
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ASTL_HUMAN
θ value	0.813845 (rank : 606)	NC score	0.038157 (rank : 1212)
Query Neighborhood Hits	1041	Target Neighborhood Hits	252	Shared Neighborhood Hits	71
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

CIC_MOUSE
θ value	0.813845 (rank : 607)	NC score	0.091870 (rank : 642)
Query Neighborhood Hits	1041	Target Neighborhood Hits	742	Shared Neighborhood Hits	221
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

COBA1_HUMAN
θ value	0.813845 (rank : 608)	NC score	0.043967 (rank : 1169)
Query Neighborhood Hits	1041	Target Neighborhood Hits	491	Shared Neighborhood Hits	133
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	0.813845 (rank : 609)	NC score	0.042378 (rank : 1182)
Query Neighborhood Hits	1041	Target Neighborhood Hits	487	Shared Neighborhood Hits	127
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

DAB1_HUMAN
θ value	0.813845 (rank : 610)	NC score	0.039382 (rank : 1196)
Query Neighborhood Hits	1041	Target Neighborhood Hits	219	Shared Neighborhood Hits	62
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DLG1_HUMAN
θ value	0.813845 (rank : 611)	NC score	0.163232 (rank : 405)
Query Neighborhood Hits	1041	Target Neighborhood Hits	290	Shared Neighborhood Hits	181
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG3_HUMAN
θ value	0.813845 (rank : 612)	NC score	0.164879 (rank : 396)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	178
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	0.813845 (rank : 613)	NC score	0.165651 (rank : 395)
Query Neighborhood Hits	1041	Target Neighborhood Hits	274	Shared Neighborhood Hits	180
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG4_HUMAN
θ value	0.813845 (rank : 614)	NC score	0.161899 (rank : 411)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	179
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	0.813845 (rank : 615)	NC score	0.162185 (rank : 409)
Query Neighborhood Hits	1041	Target Neighborhood Hits	282	Shared Neighborhood Hits	179
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

FRK_HUMAN
θ value	0.813845 (rank : 616)	NC score	0.071322 (rank : 789)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1058	Shared Neighborhood Hits	177
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

IWS1_MOUSE
θ value	0.813845 (rank : 617)	NC score	0.065170 (rank : 853)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1258	Shared Neighborhood Hits	181
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KLF17_HUMAN
θ value	0.813845 (rank : 618)	NC score	-0.005281 (rank : 1461)
Query Neighborhood Hits	1041	Target Neighborhood Hits	882	Shared Neighborhood Hits	93
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

LCK_HUMAN
θ value	0.813845 (rank : 619)	NC score	0.062804 (rank : 887)
Query Neighborhood Hits	1041	Target Neighborhood Hits	987	Shared Neighborhood Hits	137
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	0.813845 (rank : 620)	NC score	0.062507 (rank : 893)
Query Neighborhood Hits	1041	Target Neighborhood Hits	981	Shared Neighborhood Hits	134
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LMBL3_MOUSE
θ value	0.813845 (rank : 621)	NC score	0.038314 (rank : 1209)
Query Neighborhood Hits	1041	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

NEBL_HUMAN
θ value	0.813845 (rank : 622)	NC score	0.115888 (rank : 535)
Query Neighborhood Hits	1041	Target Neighborhood Hits	457	Shared Neighborhood Hits	127
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NFM_HUMAN
θ value	0.813845 (rank : 623)	NC score	0.041909 (rank : 1184)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1328	Shared Neighborhood Hits	161
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NFRKB_MOUSE
θ value	0.813845 (rank : 624)	NC score	0.059143 (rank : 956)
Query Neighborhood Hits	1041	Target Neighborhood Hits	393	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PDZ11_HUMAN
θ value	0.813845 (rank : 625)	NC score	0.180601 (rank : 357)
Query Neighborhood Hits	1041	Target Neighborhood Hits	160	Shared Neighborhood Hits	115
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PF21A_HUMAN
θ value	0.813845 (rank : 626)	NC score	0.024636 (rank : 1290)
Query Neighborhood Hits	1041	Target Neighborhood Hits	303	Shared Neighborhood Hits	37
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PO3F4_HUMAN
θ value	0.813845 (rank : 627)	NC score	0.003027 (rank : 1422)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	22
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

SHE_MOUSE
θ value	0.813845 (rank : 628)	NC score	0.060270 (rank : 935)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SRRM2_MOUSE
θ value	0.813845 (rank : 629)	NC score	0.138682 (rank : 459)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1470	Shared Neighborhood Hits	305
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYP2L_MOUSE
θ value	0.813845 (rank : 630)	NC score	0.142379 (rank : 449)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	169
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ULK1_MOUSE
θ value	0.813845 (rank : 631)	NC score	0.039193 (rank : 1201)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1214	Shared Neighborhood Hits	177
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

VINEX_HUMAN
θ value	0.813845 (rank : 632)	NC score	0.163953 (rank : 401)
Query Neighborhood Hits	1041	Target Neighborhood Hits	270	Shared Neighborhood Hits	141
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ZO2_HUMAN
θ value	0.813845 (rank : 633)	NC score	0.118054 (rank : 530)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ANKR9_MOUSE
θ value	1.06291 (rank : 634)	NC score	0.266781 (rank : 285)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BFAR_HUMAN
θ value	1.06291 (rank : 635)	NC score	0.021235 (rank : 1316)
Query Neighborhood Hits	1041	Target Neighborhood Hits	222	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BSN_HUMAN
θ value	1.06291 (rank : 636)	NC score	0.126724 (rank : 505)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1537	Shared Neighborhood Hits	343
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CBP_HUMAN
θ value	1.06291 (rank : 637)	NC score	0.098743 (rank : 604)
Query Neighborhood Hits	1041	Target Neighborhood Hits	941	Shared Neighborhood Hits	263
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CSKP_HUMAN
θ value	1.06291 (rank : 638)	NC score	0.049797 (rank : 1134)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1022	Shared Neighborhood Hits	202
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CTND2_MOUSE
θ value	1.06291 (rank : 639)	NC score	0.023502 (rank : 1297)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CUTL2_HUMAN
θ value	1.06291 (rank : 640)	NC score	0.037971 (rank : 1213)
Query Neighborhood Hits	1041	Target Neighborhood Hits	906	Shared Neighborhood Hits	133
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DLG1_MOUSE
θ value	1.06291 (rank : 641)	NC score	0.161154 (rank : 413)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	176
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

EVI1_MOUSE
θ value	1.06291 (rank : 642)	NC score	-0.010479 (rank : 1473)
Query Neighborhood Hits	1041	Target Neighborhood Hits	826	Shared Neighborhood Hits	57
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

GRAP2_HUMAN
θ value	1.06291 (rank : 643)	NC score	0.164114 (rank : 400)
Query Neighborhood Hits	1041	Target Neighborhood Hits	304	Shared Neighborhood Hits	150
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

HRBL_MOUSE
θ value	1.06291 (rank : 644)	NC score	0.057021 (rank : 996)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	83
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

JIP2_HUMAN
θ value	1.06291 (rank : 645)	NC score	0.063742 (rank : 868)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

MAVS_HUMAN
θ value	1.06291 (rank : 646)	NC score	0.068179 (rank : 826)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MEFV_HUMAN
θ value	1.06291 (rank : 647)	NC score	0.005549 (rank : 1408)
Query Neighborhood Hits	1041	Target Neighborhood Hits	431	Shared Neighborhood Hits	53
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEIS2_HUMAN
θ value	1.06291 (rank : 648)	NC score	0.008468 (rank : 1385)
Query Neighborhood Hits	1041	Target Neighborhood Hits	182	Shared Neighborhood Hits	18
SwissProt Accessions	O14770, Q96KI4, Q96KI5, Q9NRS1, Q9NRS2, Q9NRS3	Gene names	MEIS2, MRG1
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

MEIS2_MOUSE
θ value	1.06291 (rank : 649)	NC score	0.009448 (rank : 1371)
Query Neighborhood Hits	1041	Target Neighborhood Hits	208	Shared Neighborhood Hits	21
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

MIA_HUMAN
θ value	1.06291 (rank : 650)	NC score	0.041887 (rank : 1185)
Query Neighborhood Hits	1041	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q16674	Gene names	MIA
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity).

MOR2A_MOUSE
θ value	1.06291 (rank : 651)	NC score	0.032027 (rank : 1249)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	48
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

PARD3_MOUSE
θ value	1.06291 (rank : 652)	NC score	0.171121 (rank : 381)
Query Neighborhood Hits	1041	Target Neighborhood Hits	290	Shared Neighborhood Hits	139
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

REL_MOUSE
θ value	1.06291 (rank : 653)	NC score	0.053149 (rank : 1058)
Query Neighborhood Hits	1041	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

RGS12_HUMAN
θ value	1.06291 (rank : 654)	NC score	0.111690 (rank : 549)
Query Neighborhood Hits	1041	Target Neighborhood Hits	333	Shared Neighborhood Hits	154
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RNF25_HUMAN
θ value	1.06291 (rank : 655)	NC score	0.029391 (rank : 1260)
Query Neighborhood Hits	1041	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

SMAD4_MOUSE
θ value	1.06291 (rank : 656)	NC score	0.008116 (rank : 1389)
Query Neighborhood Hits	1041	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

SREC_HUMAN
θ value	1.06291 (rank : 657)	NC score	0.049916 (rank : 1133)
Query Neighborhood Hits	1041	Target Neighborhood Hits	645	Shared Neighborhood Hits	59
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

WASIP_MOUSE
θ value	1.06291 (rank : 658)	NC score	0.166459 (rank : 390)
Query Neighborhood Hits	1041	Target Neighborhood Hits	392	Shared Neighborhood Hits	205
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ZN318_MOUSE
θ value	1.06291 (rank : 659)	NC score	0.047040 (rank : 1153)
Query Neighborhood Hits	1041	Target Neighborhood Hits	642	Shared Neighborhood Hits	102
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZO3_HUMAN
θ value	1.06291 (rank : 660)	NC score	0.123800 (rank : 515)
Query Neighborhood Hits	1041	Target Neighborhood Hits	219	Shared Neighborhood Hits	139
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ANR37_MOUSE
θ value	1.38821 (rank : 661)	NC score	0.598779 (rank : 171)
Query Neighborhood Hits	1041	Target Neighborhood Hits	237	Shared Neighborhood Hits	232
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ASPX_HUMAN
θ value	1.38821 (rank : 662)	NC score	0.023671 (rank : 1296)
Query Neighborhood Hits	1041	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

ATN1_HUMAN
θ value	1.38821 (rank : 663)	NC score	0.131423 (rank : 487)
Query Neighborhood Hits	1041	Target Neighborhood Hits	676	Shared Neighborhood Hits	228
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BCL9_HUMAN
θ value	1.38821 (rank : 664)	NC score	0.097505 (rank : 612)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1008	Shared Neighborhood Hits	240
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BSN_MOUSE
θ value	1.38821 (rank : 665)	NC score	0.131048 (rank : 490)
Query Neighborhood Hits	1041	Target Neighborhood Hits	2057	Shared Neighborhood Hits	400
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CK024_MOUSE
θ value	1.38821 (rank : 666)	NC score	0.061757 (rank : 903)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CNOT4_HUMAN
θ value	1.38821 (rank : 667)	NC score	0.026689 (rank : 1277)
Query Neighborhood Hits	1041	Target Neighborhood Hits	207	Shared Neighborhood Hits	40
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

COG8_MOUSE
θ value	1.38821 (rank : 668)	NC score	0.023280 (rank : 1301)
Query Neighborhood Hits	1041	Target Neighborhood Hits	147	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

CSPG2_MOUSE
θ value	1.38821 (rank : 669)	NC score	0.048533 (rank : 1144)
Query Neighborhood Hits	1041	Target Neighborhood Hits	711	Shared Neighborhood Hits	76
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CT075_MOUSE
θ value	1.38821 (rank : 670)	NC score	0.004748 (rank : 1414)
Query Neighborhood Hits	1041	Target Neighborhood Hits	358	Shared Neighborhood Hits	26
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

DRD2_HUMAN
θ value	1.38821 (rank : 671)	NC score	-0.012254 (rank : 1479)
Query Neighborhood Hits	1041	Target Neighborhood Hits	774	Shared Neighborhood Hits	8
SwissProt Accessions	P14416, Q9NZR3, Q9UPA9	Gene names	DRD2
Domain Architecture
Description	D(2) dopamine receptor (Dopamine D2 receptor).

GAB1_HUMAN
θ value	1.38821 (rank : 672)	NC score	0.050433 (rank : 1122)
Query Neighborhood Hits	1041	Target Neighborhood Hits	279	Shared Neighborhood Hits	71
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

LEUK_HUMAN
θ value	1.38821 (rank : 673)	NC score	0.057739 (rank : 979)
Query Neighborhood Hits	1041	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LNX2_MOUSE
θ value	1.38821 (rank : 674)	NC score	0.152135 (rank : 426)
Query Neighborhood Hits	1041	Target Neighborhood Hits	407	Shared Neighborhood Hits	142
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MERTK_MOUSE
θ value	1.38821 (rank : 675)	NC score	0.040309 (rank : 1191)
Query Neighborhood Hits	1041	Target Neighborhood Hits	974	Shared Neighborhood Hits	70
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

NEST_HUMAN
θ value	1.38821 (rank : 676)	NC score	0.045118 (rank : 1163)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1305	Shared Neighborhood Hits	153
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NGEF_HUMAN
θ value	1.38821 (rank : 677)	NC score	0.089979 (rank : 651)
Query Neighborhood Hits	1041	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PACN1_HUMAN
θ value	1.38821 (rank : 678)	NC score	0.113458 (rank : 541)
Query Neighborhood Hits	1041	Target Neighborhood Hits	320	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	1.38821 (rank : 679)	NC score	0.112088 (rank : 546)
Query Neighborhood Hits	1041	Target Neighborhood Hits	283	Shared Neighborhood Hits	130
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PTN4_HUMAN
θ value	1.38821 (rank : 680)	NC score	0.035656 (rank : 1228)
Query Neighborhood Hits	1041	Target Neighborhood Hits	303	Shared Neighborhood Hits	113
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RFIP3_HUMAN
θ value	1.38821 (rank : 681)	NC score	0.058249 (rank : 970)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1055	Shared Neighborhood Hits	149
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RUSC2_MOUSE
θ value	1.38821 (rank : 682)	NC score	0.060345 (rank : 933)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	132
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SRBS1_MOUSE
θ value	1.38821 (rank : 683)	NC score	0.168536 (rank : 388)
Query Neighborhood Hits	1041	Target Neighborhood Hits	409	Shared Neighborhood Hits	179
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

UBP42_HUMAN
θ value	1.38821 (rank : 684)	NC score	0.027543 (rank : 1272)
Query Neighborhood Hits	1041	Target Neighborhood Hits	445	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

WNK2_HUMAN
θ value	1.38821 (rank : 685)	NC score	0.067734 (rank : 829)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1407	Shared Neighborhood Hits	282
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZN142_HUMAN
θ value	1.38821 (rank : 686)	NC score	-0.007614 (rank : 1465)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1007	Shared Neighborhood Hits	110
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ANR45_MOUSE
θ value	1.81305 (rank : 687)	NC score	0.501045 (rank : 207)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	187
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ARI1B_HUMAN
θ value	1.81305 (rank : 688)	NC score	0.072464 (rank : 778)
Query Neighborhood Hits	1041	Target Neighborhood Hits	567	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

BFAR_MOUSE
θ value	1.81305 (rank : 689)	NC score	0.017842 (rank : 1330)
Query Neighborhood Hits	1041	Target Neighborhood Hits	232	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

CDAN1_HUMAN
θ value	1.81305 (rank : 690)	NC score	0.044779 (rank : 1164)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

CNTP2_MOUSE
θ value	1.81305 (rank : 691)	NC score	0.022697 (rank : 1305)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	1.81305 (rank : 692)	NC score	0.024993 (rank : 1284)
Query Neighborhood Hits	1041	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CO7A1_HUMAN
θ value	1.81305 (rank : 693)	NC score	0.034279 (rank : 1232)
Query Neighborhood Hits	1041	Target Neighborhood Hits	807	Shared Neighborhood Hits	158
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CRK_HUMAN
θ value	1.81305 (rank : 694)	NC score	0.146051 (rank : 443)
Query Neighborhood Hits	1041	Target Neighborhood Hits	308	Shared Neighborhood Hits	146
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

DEN1A_HUMAN
θ value	1.81305 (rank : 695)	NC score	0.026904 (rank : 1276)
Query Neighborhood Hits	1041	Target Neighborhood Hits	176	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

EPN2_HUMAN
θ value	1.81305 (rank : 696)	NC score	0.038169 (rank : 1210)
Query Neighborhood Hits	1041	Target Neighborhood Hits	156	Shared Neighborhood Hits	50
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

ES8L3_HUMAN
θ value	1.81305 (rank : 697)	NC score	0.075043 (rank : 753)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	100
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

EVX1_HUMAN
θ value	1.81305 (rank : 698)	NC score	0.000916 (rank : 1437)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	29
SwissProt Accessions	P49640	Gene names	EVX1
Domain Architecture
Description	Homeobox even-skipped homolog protein 1 (EVX-1).

F100B_MOUSE
θ value	1.81305 (rank : 699)	NC score	0.019526 (rank : 1323)
Query Neighborhood Hits	1041	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

FAIM2_HUMAN
θ value	1.81305 (rank : 700)	NC score	0.010826 (rank : 1360)
Query Neighborhood Hits	1041	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BWQ8, Q9UJY9, Q9Y2F7	Gene names	FAIM2, KIAA0950, LFG, TMBIM2
Domain Architecture
Description	Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Transmembrane BAX inhibitor motif-containing protein 2).

FBLI1_MOUSE
θ value	1.81305 (rank : 701)	NC score	0.027732 (rank : 1271)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

FXL19_MOUSE
θ value	1.81305 (rank : 702)	NC score	0.020973 (rank : 1317)
Query Neighborhood Hits	1041	Target Neighborhood Hits	217	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

IF4B_HUMAN
θ value	1.81305 (rank : 703)	NC score	0.032073 (rank : 1248)
Query Neighborhood Hits	1041	Target Neighborhood Hits	417	Shared Neighborhood Hits	66
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

K0310_HUMAN
θ value	1.81305 (rank : 704)	NC score	0.073449 (rank : 767)
Query Neighborhood Hits	1041	Target Neighborhood Hits	420	Shared Neighborhood Hits	129
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K0319_HUMAN
θ value	1.81305 (rank : 705)	NC score	0.033700 (rank : 1237)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

K1543_MOUSE
θ value	1.81305 (rank : 706)	NC score	0.080401 (rank : 712)
Query Neighborhood Hits	1041	Target Neighborhood Hits	497	Shared Neighborhood Hits	148
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KCNQ4_HUMAN
θ value	1.81305 (rank : 707)	NC score	0.002659 (rank : 1423)
Query Neighborhood Hits	1041	Target Neighborhood Hits	136	Shared Neighborhood Hits	11
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

MCM3A_MOUSE
θ value	1.81305 (rank : 708)	NC score	0.013456 (rank : 1351)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

MPP3_MOUSE
θ value	1.81305 (rank : 709)	NC score	0.097996 (rank : 608)
Query Neighborhood Hits	1041	Target Neighborhood Hits	165	Shared Neighborhood Hits	117
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MYOD1_HUMAN
θ value	1.81305 (rank : 710)	NC score	0.008676 (rank : 1383)
Query Neighborhood Hits	1041	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

OBSCN_HUMAN
θ value	1.81305 (rank : 711)	NC score	0.038165 (rank : 1211)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1931	Shared Neighborhood Hits	252
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PUNC_MOUSE
θ value	1.81305 (rank : 712)	NC score	-0.000956 (rank : 1445)
Query Neighborhood Hits	1041	Target Neighborhood Hits	501	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RP1L1_HUMAN
θ value	1.81305 (rank : 713)	NC score	0.083096 (rank : 684)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1072	Shared Neighborhood Hits	195
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SMOO_HUMAN
θ value	1.81305 (rank : 714)	NC score	0.059142 (rank : 957)
Query Neighborhood Hits	1041	Target Neighborhood Hits	391	Shared Neighborhood Hits	135
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SNPC4_HUMAN
θ value	1.81305 (rank : 715)	NC score	0.070102 (rank : 803)
Query Neighborhood Hits	1041	Target Neighborhood Hits	589	Shared Neighborhood Hits	163
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SNTA1_HUMAN
θ value	1.81305 (rank : 716)	NC score	0.144730 (rank : 445)
Query Neighborhood Hits	1041	Target Neighborhood Hits	186	Shared Neighborhood Hits	130
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SORC1_MOUSE
θ value	1.81305 (rank : 717)	NC score	0.006848 (rank : 1398)
Query Neighborhood Hits	1041	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

SPR1A_HUMAN
θ value	1.81305 (rank : 718)	NC score	0.033525 (rank : 1240)
Query Neighborhood Hits	1041	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SPR1B_HUMAN
θ value	1.81305 (rank : 719)	NC score	0.032251 (rank : 1245)
Query Neighborhood Hits	1041	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SPTA2_HUMAN
θ value	1.81305 (rank : 720)	NC score	0.071747 (rank : 787)
Query Neighborhood Hits	1041	Target Neighborhood Hits	888	Shared Neighborhood Hits	162
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRBS1_HUMAN
θ value	1.81305 (rank : 721)	NC score	0.162200 (rank : 408)
Query Neighborhood Hits	1041	Target Neighborhood Hits	396	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRRM1_MOUSE
θ value	1.81305 (rank : 722)	NC score	0.148822 (rank : 435)
Query Neighborhood Hits	1041	Target Neighborhood Hits	966	Shared Neighborhood Hits	257
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TIP60_HUMAN
θ value	1.81305 (rank : 723)	NC score	0.015581 (rank : 1344)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TRI46_HUMAN
θ value	1.81305 (rank : 724)	NC score	0.006578 (rank : 1399)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

WNK1_HUMAN
θ value	1.81305 (rank : 725)	NC score	0.050501 (rank : 1120)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1158	Shared Neighborhood Hits	178
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZN645_HUMAN
θ value	1.81305 (rank : 726)	NC score	0.033399 (rank : 1241)
Query Neighborhood Hits	1041	Target Neighborhood Hits	265	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ACK1_MOUSE
θ value	2.36792 (rank : 727)	NC score	0.058039 (rank : 975)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1080	Shared Neighborhood Hits	200
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ANKY1_HUMAN
θ value	2.36792 (rank : 728)	NC score	0.467986 (rank : 222)
Query Neighborhood Hits	1041	Target Neighborhood Hits	248	Shared Neighborhood Hits	202
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANKZ1_HUMAN
θ value	2.36792 (rank : 729)	NC score	0.280571 (rank : 281)
Query Neighborhood Hits	1041	Target Neighborhood Hits	236	Shared Neighborhood Hits	164
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ATF2_HUMAN
θ value	2.36792 (rank : 730)	NC score	0.031343 (rank : 1251)
Query Neighborhood Hits	1041	Target Neighborhood Hits	402	Shared Neighborhood Hits	73
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	2.36792 (rank : 731)	NC score	0.029984 (rank : 1256)
Query Neighborhood Hits	1041	Target Neighborhood Hits	397	Shared Neighborhood Hits	74
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATS14_HUMAN
θ value	2.36792 (rank : 732)	NC score	0.007939 (rank : 1392)
Query Neighborhood Hits	1041	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

C2TA_HUMAN
θ value	2.36792 (rank : 733)	NC score	0.024131 (rank : 1292)
Query Neighborhood Hits	1041	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CN032_HUMAN
θ value	2.36792 (rank : 734)	NC score	0.130309 (rank : 496)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	132
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CNOT4_MOUSE
θ value	2.36792 (rank : 735)	NC score	0.034515 (rank : 1230)
Query Neighborhood Hits	1041	Target Neighborhood Hits	277	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

COBA2_MOUSE
θ value	2.36792 (rank : 736)	NC score	0.036167 (rank : 1222)
Query Neighborhood Hits	1041	Target Neighborhood Hits	501	Shared Neighborhood Hits	129
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CT174_HUMAN
θ value	2.36792 (rank : 737)	NC score	0.053154 (rank : 1057)
Query Neighborhood Hits	1041	Target Neighborhood Hits	181	Shared Neighborhood Hits	62
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

E41LB_HUMAN
θ value	2.36792 (rank : 738)	NC score	0.005486 (rank : 1410)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

FBSH_HUMAN
θ value	2.36792 (rank : 739)	NC score	0.035982 (rank : 1225)
Query Neighborhood Hits	1041	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

FLI1_MOUSE
θ value	2.36792 (rank : 740)	NC score	0.004156 (rank : 1416)
Query Neighborhood Hits	1041	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	P26323	Gene names	Fli1, Fli-1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Retroviral integration site protein Fli-1).

FMN2_MOUSE
θ value	2.36792 (rank : 741)	NC score	0.068529 (rank : 819)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

GP108_MOUSE
θ value	2.36792 (rank : 742)	NC score	0.013606 (rank : 1350)
Query Neighborhood Hits	1041	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

HES2_MOUSE
θ value	2.36792 (rank : 743)	NC score	0.008517 (rank : 1384)
Query Neighborhood Hits	1041	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HXB13_HUMAN
θ value	2.36792 (rank : 744)	NC score	0.000549 (rank : 1439)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	24
SwissProt Accessions	Q92826, Q96QM4, Q99810	Gene names	HOXB13
Domain Architecture
Description	Homeobox protein Hox-B13.

HXD3_HUMAN
θ value	2.36792 (rank : 745)	NC score	0.008924 (rank : 1381)
Query Neighborhood Hits	1041	Target Neighborhood Hits	433	Shared Neighborhood Hits	59
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

IL16_HUMAN
θ value	2.36792 (rank : 746)	NC score	0.139116 (rank : 456)
Query Neighborhood Hits	1041	Target Neighborhood Hits	207	Shared Neighborhood Hits	116
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

JIP3_HUMAN
θ value	2.36792 (rank : 747)	NC score	0.038919 (rank : 1203)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1039	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

LAD1_MOUSE
θ value	2.36792 (rank : 748)	NC score	0.070897 (rank : 794)
Query Neighborhood Hits	1041	Target Neighborhood Hits	391	Shared Neighborhood Hits	89
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MBB1A_HUMAN
θ value	2.36792 (rank : 749)	NC score	0.049727 (rank : 1136)
Query Neighborhood Hits	1041	Target Neighborhood Hits	665	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MINT_MOUSE
θ value	2.36792 (rank : 750)	NC score	0.075411 (rank : 750)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1514	Shared Neighborhood Hits	249
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL4_HUMAN
θ value	2.36792 (rank : 751)	NC score	0.105033 (rank : 574)
Query Neighborhood Hits	1041	Target Neighborhood Hits	722	Shared Neighborhood Hits	223
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MPP3_HUMAN
θ value	2.36792 (rank : 752)	NC score	0.096192 (rank : 615)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	118
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

NCOA6_MOUSE
θ value	2.36792 (rank : 753)	NC score	0.111054 (rank : 554)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1076	Shared Neighborhood Hits	248
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PDCD1_HUMAN
θ value	2.36792 (rank : 754)	NC score	0.007945 (rank : 1391)
Query Neighborhood Hits	1041	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q15116, O00517	Gene names	PDCD1, PD1
Domain Architecture
Description	Programmed cell death protein 1 precursor (Protein PD-1) (hPD-1) (CD279 antigen).

PDLI2_HUMAN
θ value	2.36792 (rank : 755)	NC score	0.119128 (rank : 527)
Query Neighborhood Hits	1041	Target Neighborhood Hits	245	Shared Neighborhood Hits	113
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PO6F1_MOUSE
θ value	2.36792 (rank : 756)	NC score	0.014576 (rank : 1348)
Query Neighborhood Hits	1041	Target Neighborhood Hits	581	Shared Neighborhood Hits	89
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PTN13_HUMAN
θ value	2.36792 (rank : 757)	NC score	0.097958 (rank : 610)
Query Neighborhood Hits	1041	Target Neighborhood Hits	471	Shared Neighborhood Hits	152
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	2.36792 (rank : 758)	NC score	0.094184 (rank : 625)
Query Neighborhood Hits	1041	Target Neighborhood Hits	426	Shared Neighborhood Hits	155
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

RPP25_HUMAN
θ value	2.36792 (rank : 759)	NC score	0.020766 (rank : 1318)
Query Neighborhood Hits	1041	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BUL9, Q9NX88	Gene names	RPP25
Domain Architecture	No domain graphic available
Description	Ribonuclease P protein subunit p25 (EC 3.1.26.5) (RNase P protein subunit p25).

RTN4R_MOUSE
θ value	2.36792 (rank : 760)	NC score	-0.001828 (rank : 1451)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

SALL1_HUMAN
θ value	2.36792 (rank : 761)	NC score	-0.007196 (rank : 1464)
Query Neighborhood Hits	1041	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

SAPS3_HUMAN
θ value	2.36792 (rank : 762)	NC score	0.019732 (rank : 1322)
Query Neighborhood Hits	1041	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).

SF3B1_HUMAN
θ value	2.36792 (rank : 763)	NC score	0.048602 (rank : 1141)
Query Neighborhood Hits	1041	Target Neighborhood Hits	341	Shared Neighborhood Hits	86
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	2.36792 (rank : 764)	NC score	0.049416 (rank : 1137)
Query Neighborhood Hits	1041	Target Neighborhood Hits	352	Shared Neighborhood Hits	88
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SH3G3_MOUSE
θ value	2.36792 (rank : 765)	NC score	0.140768 (rank : 451)
Query Neighborhood Hits	1041	Target Neighborhood Hits	236	Shared Neighborhood Hits	124
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SIPA1_HUMAN
θ value	2.36792 (rank : 766)	NC score	0.069696 (rank : 805)
Query Neighborhood Hits	1041	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

TBX18_HUMAN
θ value	2.36792 (rank : 767)	NC score	0.003188 (rank : 1419)
Query Neighborhood Hits	1041	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TCF20_MOUSE
θ value	2.36792 (rank : 768)	NC score	0.029627 (rank : 1259)
Query Neighborhood Hits	1041	Target Neighborhood Hits	396	Shared Neighborhood Hits	80
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TENS1_HUMAN
θ value	2.36792 (rank : 769)	NC score	0.051827 (rank : 1089)
Query Neighborhood Hits	1041	Target Neighborhood Hits	400	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TIAM1_MOUSE
θ value	2.36792 (rank : 770)	NC score	0.109024 (rank : 559)
Query Neighborhood Hits	1041	Target Neighborhood Hits	205	Shared Neighborhood Hits	79
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TRI66_HUMAN
θ value	2.36792 (rank : 771)	NC score	0.023739 (rank : 1294)
Query Neighborhood Hits	1041	Target Neighborhood Hits	479	Shared Neighborhood Hits	93
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXLNB_HUMAN
θ value	2.36792 (rank : 772)	NC score	0.055442 (rank : 1018)
Query Neighborhood Hits	1041	Target Neighborhood Hits	912	Shared Neighborhood Hits	150
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

UBP28_MOUSE
θ value	2.36792 (rank : 773)	NC score	0.007220 (rank : 1394)
Query Neighborhood Hits	1041	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ULK2_HUMAN
θ value	2.36792 (rank : 774)	NC score	0.031752 (rank : 1250)
Query Neighborhood Hits	1041	Target Neighborhood Hits	979	Shared Neighborhood Hits	109
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

WIRE_MOUSE
θ value	2.36792 (rank : 775)	NC score	0.138760 (rank : 458)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	160
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZN384_HUMAN
θ value	2.36792 (rank : 776)	NC score	-0.012733 (rank : 1482)
Query Neighborhood Hits	1041	Target Neighborhood Hits	764	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF68, O15407, Q8N938	Gene names	ZNF384, CAGH1, CIZ, NMP4
Domain Architecture	No domain graphic available
Description	Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein).

ZN447_HUMAN
θ value	2.36792 (rank : 777)	NC score	-0.004259 (rank : 1458)
Query Neighborhood Hits	1041	Target Neighborhood Hits	899	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

ZN750_MOUSE
θ value	2.36792 (rank : 778)	NC score	0.049364 (rank : 1138)
Query Neighborhood Hits	1041	Target Neighborhood Hits	346	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ZO3_MOUSE
θ value	2.36792 (rank : 779)	NC score	0.125808 (rank : 510)
Query Neighborhood Hits	1041	Target Neighborhood Hits	224	Shared Neighborhood Hits	140
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ANKR9_HUMAN
θ value	3.0926 (rank : 780)	NC score	0.222127 (rank : 304)
Query Neighborhood Hits	1041	Target Neighborhood Hits	99	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

AT8B2_HUMAN
θ value	3.0926 (rank : 781)	NC score	0.001565 (rank : 1433)
Query Neighborhood Hits	1041	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	P98198, Q96I43, Q96NQ7	Gene names	ATP8B2, ATPID, KIAA1137
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase ID (EC 3.6.3.1) (ATPase class I type 8B member 2).

CC040_HUMAN
θ value	3.0926 (rank : 782)	NC score	0.011076 (rank : 1359)
Query Neighborhood Hits	1041	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UXB0, Q8TA84	Gene names	C3orf40
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf40 precursor.

CD2A1_MOUSE
θ value	3.0926 (rank : 783)	NC score	0.579681 (rank : 180)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	196
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CO2A1_HUMAN
θ value	3.0926 (rank : 784)	NC score	0.039303 (rank : 1199)
Query Neighborhood Hits	1041	Target Neighborhood Hits	486	Shared Neighborhood Hits	129
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	3.0926 (rank : 785)	NC score	0.037898 (rank : 1215)
Query Neighborhood Hits	1041	Target Neighborhood Hits	483	Shared Neighborhood Hits	121
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CT177_HUMAN
θ value	3.0926 (rank : 786)	NC score	0.016415 (rank : 1340)
Query Neighborhood Hits	1041	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NTX9, Q9NTA3	Gene names	C20orf177
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf177.

CTBP2_HUMAN
θ value	3.0926 (rank : 787)	NC score	0.005908 (rank : 1405)
Query Neighborhood Hits	1041	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P56545, O43449	Gene names	CTBP2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

DEDD_HUMAN
θ value	3.0926 (rank : 788)	NC score	0.009338 (rank : 1374)
Query Neighborhood Hits	1041	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	O75618, O60737	Gene names	DEDD, DEDPRO1, DEFT
Domain Architecture
Description	Death effector domain-containing protein (Death effector domain- containing testicular molecule) (DEDPro1) (FLDED-1).

EPHB3_HUMAN
θ value	3.0926 (rank : 789)	NC score	0.047948 (rank : 1145)
Query Neighborhood Hits	1041	Target Neighborhood Hits	996	Shared Neighborhood Hits	92
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

ETV6_HUMAN
θ value	3.0926 (rank : 790)	NC score	0.010378 (rank : 1362)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

FOXH1_HUMAN
θ value	3.0926 (rank : 791)	NC score	0.009156 (rank : 1378)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

GA2L1_MOUSE
θ value	3.0926 (rank : 792)	NC score	0.033932 (rank : 1236)
Query Neighborhood Hits	1041	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GAB1_MOUSE
θ value	3.0926 (rank : 793)	NC score	0.043064 (rank : 1177)
Query Neighborhood Hits	1041	Target Neighborhood Hits	233	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAK8_HUMAN
θ value	3.0926 (rank : 794)	NC score	0.003385 (rank : 1418)
Query Neighborhood Hits	1041	Target Neighborhood Hits	145	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GMEB1_MOUSE
θ value	3.0926 (rank : 795)	NC score	0.007966 (rank : 1390)
Query Neighborhood Hits	1041	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

GP124_MOUSE
θ value	3.0926 (rank : 796)	NC score	-0.000199 (rank : 1443)
Query Neighborhood Hits	1041	Target Neighborhood Hits	423	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GPS2_HUMAN
θ value	3.0926 (rank : 797)	NC score	0.043496 (rank : 1175)
Query Neighborhood Hits	1041	Target Neighborhood Hits	459	Shared Neighborhood Hits	74
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GTSE1_HUMAN
θ value	3.0926 (rank : 798)	NC score	0.056237 (rank : 1007)
Query Neighborhood Hits	1041	Target Neighborhood Hits	193	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

HN1L_MOUSE
θ value	3.0926 (rank : 799)	NC score	0.021941 (rank : 1310)
Query Neighborhood Hits	1041	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PGH2	Gene names	D17Ertd441e
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

HNF6_HUMAN
θ value	3.0926 (rank : 800)	NC score	0.009885 (rank : 1363)
Query Neighborhood Hits	1041	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBC0, Q99744, Q9UMR6	Gene names	ONECUT1, HNF6, HNF6A
Domain Architecture
Description	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1).

HSF1_MOUSE
θ value	3.0926 (rank : 801)	NC score	0.034137 (rank : 1234)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	76
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HXB13_MOUSE
θ value	3.0926 (rank : 802)	NC score	0.000229 (rank : 1441)
Query Neighborhood Hits	1041	Target Neighborhood Hits	384	Shared Neighborhood Hits	26
SwissProt Accessions	P70321, Q80Y12	Gene names	Hoxb13
Domain Architecture
Description	Homeobox protein Hox-B13.

IQEC3_MOUSE
θ value	3.0926 (rank : 803)	NC score	0.025153 (rank : 1283)
Query Neighborhood Hits	1041	Target Neighborhood Hits	274	Shared Neighborhood Hits	82
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IWS1_HUMAN
θ value	3.0926 (rank : 804)	NC score	0.066333 (rank : 843)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1241	Shared Neighborhood Hits	163
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JPH2_HUMAN
θ value	3.0926 (rank : 805)	NC score	0.041286 (rank : 1189)
Query Neighborhood Hits	1041	Target Neighborhood Hits	639	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MILK1_HUMAN
θ value	3.0926 (rank : 806)	NC score	0.066805 (rank : 837)
Query Neighborhood Hits	1041	Target Neighborhood Hits	427	Shared Neighborhood Hits	153
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NFAC1_MOUSE
θ value	3.0926 (rank : 807)	NC score	0.009545 (rank : 1370)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	24
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

ORAI3_MOUSE
θ value	3.0926 (rank : 808)	NC score	0.008347 (rank : 1387)
Query Neighborhood Hits	1041	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P8G8	Gene names	Tmem142c, Orai3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

OTOR_MOUSE
θ value	3.0926 (rank : 809)	NC score	0.030317 (rank : 1255)
Query Neighborhood Hits	1041	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JIE3	Gene names	Otor, Mial
Domain Architecture
Description	Otoraplin precursor (Melanoma inhibitory activity-like protein).

PALB2_MOUSE
θ value	3.0926 (rank : 810)	NC score	0.023177 (rank : 1302)
Query Neighborhood Hits	1041	Target Neighborhood Hits	133	Shared Neighborhood Hits	27
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PANK1_HUMAN
θ value	3.0926 (rank : 811)	NC score	0.008316 (rank : 1388)
Query Neighborhood Hits	1041	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

PCDAB_HUMAN
θ value	3.0926 (rank : 812)	NC score	-0.003568 (rank : 1457)
Query Neighborhood Hits	1041	Target Neighborhood Hits	211	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5I1, O75279	Gene names	PCDHA11
Domain Architecture
Description	Protocadherin alpha 11 precursor (PCDH-alpha11).

PRRT3_MOUSE
θ value	3.0926 (rank : 813)	NC score	0.076744 (rank : 736)
Query Neighborhood Hits	1041	Target Neighborhood Hits	162	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RTN1_MOUSE
θ value	3.0926 (rank : 814)	NC score	0.033622 (rank : 1238)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

RX_HUMAN
θ value	3.0926 (rank : 815)	NC score	0.003034 (rank : 1421)
Query Neighborhood Hits	1041	Target Neighborhood Hits	423	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SNTA1_MOUSE
θ value	3.0926 (rank : 816)	NC score	0.140037 (rank : 454)
Query Neighborhood Hits	1041	Target Neighborhood Hits	170	Shared Neighborhood Hits	122
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SPEG_MOUSE
θ value	3.0926 (rank : 817)	NC score	0.039915 (rank : 1194)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1959	Shared Neighborhood Hits	293
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPT5H_HUMAN
θ value	3.0926 (rank : 818)	NC score	0.060832 (rank : 924)
Query Neighborhood Hits	1041	Target Neighborhood Hits	436	Shared Neighborhood Hits	119
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	3.0926 (rank : 819)	NC score	0.061127 (rank : 916)
Query Neighborhood Hits	1041	Target Neighborhood Hits	437	Shared Neighborhood Hits	118
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

STAT2_MOUSE
θ value	3.0926 (rank : 820)	NC score	0.009744 (rank : 1366)
Query Neighborhood Hits	1041	Target Neighborhood Hits	175	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

TYRO3_MOUSE
θ value	3.0926 (rank : 821)	NC score	0.039376 (rank : 1197)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1007	Shared Neighborhood Hits	72
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

WIRE_HUMAN
θ value	3.0926 (rank : 822)	NC score	0.140483 (rank : 452)
Query Neighborhood Hits	1041	Target Neighborhood Hits	329	Shared Neighborhood Hits	168
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ZC3H3_MOUSE
θ value	3.0926 (rank : 823)	NC score	0.026564 (rank : 1278)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZN318_HUMAN
θ value	3.0926 (rank : 824)	NC score	0.038491 (rank : 1208)
Query Neighborhood Hits	1041	Target Neighborhood Hits	497	Shared Neighborhood Hits	88
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ATX2L_HUMAN
θ value	4.03905 (rank : 825)	NC score	0.071732 (rank : 788)
Query Neighborhood Hits	1041	Target Neighborhood Hits	443	Shared Neighborhood Hits	149
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BAG3_HUMAN
θ value	4.03905 (rank : 826)	NC score	0.082718 (rank : 690)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	104
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CAMKV_HUMAN
θ value	4.03905 (rank : 827)	NC score	0.024244 (rank : 1291)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1084	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CD2_HUMAN
θ value	4.03905 (rank : 828)	NC score	0.041710 (rank : 1186)
Query Neighborhood Hits	1041	Target Neighborhood Hits	504	Shared Neighborhood Hits	100
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CJ078_MOUSE
θ value	4.03905 (rank : 829)	NC score	0.107960 (rank : 565)
Query Neighborhood Hits	1041	Target Neighborhood Hits	559	Shared Neighborhood Hits	161
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CLR59_HUMAN
θ value	4.03905 (rank : 830)	NC score	0.251301 (rank : 290)
Query Neighborhood Hits	1041	Target Neighborhood Hits	163	Shared Neighborhood Hits	142
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CO039_HUMAN
θ value	4.03905 (rank : 831)	NC score	0.077856 (rank : 729)
Query Neighborhood Hits	1041	Target Neighborhood Hits	264	Shared Neighborhood Hits	110
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO9A1_HUMAN
θ value	4.03905 (rank : 832)	NC score	0.029648 (rank : 1258)
Query Neighborhood Hits	1041	Target Neighborhood Hits	420	Shared Neighborhood Hits	97
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A1_MOUSE
θ value	4.03905 (rank : 833)	NC score	0.029175 (rank : 1263)
Query Neighborhood Hits	1041	Target Neighborhood Hits	477	Shared Neighborhood Hits	106
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

DCC_MOUSE
θ value	4.03905 (rank : 834)	NC score	0.010382 (rank : 1361)
Query Neighborhood Hits	1041	Target Neighborhood Hits	896	Shared Neighborhood Hits	122
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DCJ14_MOUSE
θ value	4.03905 (rank : 835)	NC score	0.002418 (rank : 1427)
Query Neighborhood Hits	1041	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	Q921R4, Q3TX73, Q8BUU3, Q9CYB7	Gene names	Dnajc14
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14.

EPHB3_MOUSE
θ value	4.03905 (rank : 836)	NC score	0.047591 (rank : 1150)
Query Neighborhood Hits	1041	Target Neighborhood Hits	996	Shared Neighborhood Hits	90
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

ERCC5_MOUSE
θ value	4.03905 (rank : 837)	NC score	0.017571 (rank : 1335)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

ETV6_MOUSE
θ value	4.03905 (rank : 838)	NC score	0.006044 (rank : 1402)
Query Neighborhood Hits	1041	Target Neighborhood Hits	103	Shared Neighborhood Hits	13
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

FMN2_HUMAN
θ value	4.03905 (rank : 839)	NC score	0.087108 (rank : 659)
Query Neighborhood Hits	1041	Target Neighborhood Hits	484	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GLT12_MOUSE
θ value	4.03905 (rank : 840)	NC score	-0.001957 (rank : 1452)
Query Neighborhood Hits	1041	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGT9	Gene names	Galnt12
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12).

GON4L_MOUSE
θ value	4.03905 (rank : 841)	NC score	0.041495 (rank : 1187)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HNF6_MOUSE
θ value	4.03905 (rank : 842)	NC score	0.009079 (rank : 1380)
Query Neighborhood Hits	1041	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	O08755	Gene names	Onecut1, Hnf6, Hnf6a
Domain Architecture
Description	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1).

IL16_MOUSE
θ value	4.03905 (rank : 843)	NC score	0.131564 (rank : 485)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	115
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IL3B2_MOUSE
θ value	4.03905 (rank : 844)	NC score	0.032172 (rank : 1246)
Query Neighborhood Hits	1041	Target Neighborhood Hits	372	Shared Neighborhood Hits	96
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

LIPA2_HUMAN
θ value	4.03905 (rank : 845)	NC score	0.052651 (rank : 1067)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1044	Shared Neighborhood Hits	105
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
θ value	4.03905 (rank : 846)	NC score	0.052613 (rank : 1068)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1282	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA4_HUMAN
θ value	4.03905 (rank : 847)	NC score	0.034234 (rank : 1233)
Query Neighborhood Hits	1041	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

LN28B_HUMAN
θ value	4.03905 (rank : 848)	NC score	0.009561 (rank : 1369)
Query Neighborhood Hits	1041	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZN17	Gene names	LIN28B, CSDD2
Domain Architecture	No domain graphic available
Description	Lin-28 homolog B.

LRCH4_MOUSE
θ value	4.03905 (rank : 849)	NC score	0.017755 (rank : 1332)
Query Neighborhood Hits	1041	Target Neighborhood Hits	302	Shared Neighborhood Hits	39
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

MYO15_HUMAN
θ value	4.03905 (rank : 850)	NC score	0.039362 (rank : 1198)
Query Neighborhood Hits	1041	Target Neighborhood Hits	671	Shared Neighborhood Hits	180
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PCX3_MOUSE
θ value	4.03905 (rank : 851)	NC score	0.038502 (rank : 1207)
Query Neighborhood Hits	1041	Target Neighborhood Hits	134	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

PELP1_MOUSE
θ value	4.03905 (rank : 852)	NC score	0.087392 (rank : 657)
Query Neighborhood Hits	1041	Target Neighborhood Hits	709	Shared Neighborhood Hits	184
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PHLPP_HUMAN
θ value	4.03905 (rank : 853)	NC score	0.022277 (rank : 1307)
Query Neighborhood Hits	1041	Target Neighborhood Hits	604	Shared Neighborhood Hits	107
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PITM2_HUMAN
θ value	4.03905 (rank : 854)	NC score	0.002594 (rank : 1426)
Query Neighborhood Hits	1041	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

PREX1_HUMAN
θ value	4.03905 (rank : 855)	NC score	0.098406 (rank : 607)
Query Neighborhood Hits	1041	Target Neighborhood Hits	177	Shared Neighborhood Hits	70
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PYGO1_HUMAN
θ value	4.03905 (rank : 856)	NC score	0.017102 (rank : 1337)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

RBP2_HUMAN
θ value	4.03905 (rank : 857)	NC score	0.006315 (rank : 1400)
Query Neighborhood Hits	1041	Target Neighborhood Hits	249	Shared Neighborhood Hits	44
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

SALL2_MOUSE
θ value	4.03905 (rank : 858)	NC score	-0.002611 (rank : 1455)
Query Neighborhood Hits	1041	Target Neighborhood Hits	836	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

SLIK3_MOUSE
θ value	4.03905 (rank : 859)	NC score	-0.003448 (rank : 1456)
Query Neighborhood Hits	1041	Target Neighborhood Hits	308	Shared Neighborhood Hits	19
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

SOX13_HUMAN
θ value	4.03905 (rank : 860)	NC score	0.028496 (rank : 1266)
Query Neighborhood Hits	1041	Target Neighborhood Hits	464	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX17_MOUSE
θ value	4.03905 (rank : 861)	NC score	0.017510 (rank : 1336)
Query Neighborhood Hits	1041	Target Neighborhood Hits	223	Shared Neighborhood Hits	51
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

TBCD1_HUMAN
θ value	4.03905 (rank : 862)	NC score	0.017663 (rank : 1333)
Query Neighborhood Hits	1041	Target Neighborhood Hits	276	Shared Neighborhood Hits	29
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TIP60_MOUSE
θ value	4.03905 (rank : 863)	NC score	0.014550 (rank : 1349)
Query Neighborhood Hits	1041	Target Neighborhood Hits	95	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TMEPA_HUMAN
θ value	4.03905 (rank : 864)	NC score	0.012314 (rank : 1354)
Query Neighborhood Hits	1041	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

TSC1_HUMAN
θ value	4.03905 (rank : 865)	NC score	0.037537 (rank : 1216)
Query Neighborhood Hits	1041	Target Neighborhood Hits	765	Shared Neighborhood Hits	90
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ZIC1_HUMAN
θ value	4.03905 (rank : 866)	NC score	-0.012439 (rank : 1480)
Query Neighborhood Hits	1041	Target Neighborhood Hits	710	Shared Neighborhood Hits	34
SwissProt Accessions	Q15915	Gene names	ZIC1, ZIC
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1).

AATK_HUMAN
θ value	5.27518 (rank : 867)	NC score	0.046564 (rank : 1155)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1243	Shared Neighborhood Hits	178
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ABI1_HUMAN
θ value	5.27518 (rank : 868)	NC score	0.152146 (rank : 425)
Query Neighborhood Hits	1041	Target Neighborhood Hits	257	Shared Neighborhood Hits	164
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	5.27518 (rank : 869)	NC score	0.146361 (rank : 441)
Query Neighborhood Hits	1041	Target Neighborhood Hits	246	Shared Neighborhood Hits	155
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

AFAD_HUMAN
θ value	5.27518 (rank : 870)	NC score	0.123887 (rank : 514)
Query Neighborhood Hits	1041	Target Neighborhood Hits	689	Shared Neighborhood Hits	181
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ANR45_HUMAN
θ value	5.27518 (rank : 871)	NC score	0.469073 (rank : 220)
Query Neighborhood Hits	1041	Target Neighborhood Hits	201	Shared Neighborhood Hits	182
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ARHGG_HUMAN
θ value	5.27518 (rank : 872)	NC score	0.076246 (rank : 744)
Query Neighborhood Hits	1041	Target Neighborhood Hits	129	Shared Neighborhood Hits	54
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ATX2L_MOUSE
θ value	5.27518 (rank : 873)	NC score	0.060364 (rank : 932)
Query Neighborhood Hits	1041	Target Neighborhood Hits	401	Shared Neighborhood Hits	123
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

BCL9_MOUSE
θ value	5.27518 (rank : 874)	NC score	0.092117 (rank : 638)
Query Neighborhood Hits	1041	Target Neighborhood Hits	770	Shared Neighborhood Hits	204
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CD248_MOUSE
θ value	5.27518 (rank : 875)	NC score	0.054904 (rank : 1026)
Query Neighborhood Hits	1041	Target Neighborhood Hits	578	Shared Neighborhood Hits	105
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CJ012_HUMAN
θ value	5.27518 (rank : 876)	NC score	0.042971 (rank : 1179)
Query Neighborhood Hits	1041	Target Neighborhood Hits	467	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CPT1A_HUMAN
θ value	5.27518 (rank : 877)	NC score	0.001159 (rank : 1435)
Query Neighborhood Hits	1041	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P50416, Q8TCU0, Q9BWK0	Gene names	CPT1A, CPT1
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, liver isoform (EC 2.3.1.21) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A).

CS007_HUMAN
θ value	5.27518 (rank : 878)	NC score	0.070194 (rank : 801)
Query Neighborhood Hits	1041	Target Neighborhood Hits	401	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

EGFR_HUMAN
θ value	5.27518 (rank : 879)	NC score	0.041462 (rank : 1188)
Query Neighborhood Hits	1041	Target Neighborhood Hits	939	Shared Neighborhood Hits	75
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EM55_MOUSE
θ value	5.27518 (rank : 880)	NC score	0.104478 (rank : 577)
Query Neighborhood Hits	1041	Target Neighborhood Hits	221	Shared Neighborhood Hits	166
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

EP300_HUMAN
θ value	5.27518 (rank : 881)	NC score	0.094854 (rank : 623)
Query Neighborhood Hits	1041	Target Neighborhood Hits	821	Shared Neighborhood Hits	236
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ERBB2_HUMAN
θ value	5.27518 (rank : 882)	NC score	0.043114 (rank : 1176)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1073	Shared Neighborhood Hits	109
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

FHOD1_HUMAN
θ value	5.27518 (rank : 883)	NC score	0.022087 (rank : 1309)
Query Neighborhood Hits	1041	Target Neighborhood Hits	184	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FOXGA_HUMAN
θ value	5.27518 (rank : 884)	NC score	0.003418 (rank : 1417)
Query Neighborhood Hits	1041	Target Neighborhood Hits	132	Shared Neighborhood Hits	23
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

GNAS1_MOUSE
θ value	5.27518 (rank : 885)	NC score	0.039236 (rank : 1200)
Query Neighborhood Hits	1041	Target Neighborhood Hits	651	Shared Neighborhood Hits	163
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HIC1_MOUSE
θ value	5.27518 (rank : 886)	NC score	-0.010217 (rank : 1472)
Query Neighborhood Hits	1041	Target Neighborhood Hits	863	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

HTRA2_HUMAN
θ value	5.27518 (rank : 887)	NC score	0.016806 (rank : 1339)
Query Neighborhood Hits	1041	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	5.27518 (rank : 888)	NC score	0.014919 (rank : 1346)
Query Neighborhood Hits	1041	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HXA3_MOUSE
θ value	5.27518 (rank : 889)	NC score	0.028746 (rank : 1264)
Query Neighborhood Hits	1041	Target Neighborhood Hits	558	Shared Neighborhood Hits	139
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IL3RB_MOUSE
θ value	5.27518 (rank : 890)	NC score	0.025219 (rank : 1282)
Query Neighborhood Hits	1041	Target Neighborhood Hits	355	Shared Neighborhood Hits	81
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

LIPA1_HUMAN
θ value	5.27518 (rank : 891)	NC score	0.050843 (rank : 1112)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1294	Shared Neighborhood Hits	122
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MINT_HUMAN
θ value	5.27518 (rank : 892)	NC score	0.076038 (rank : 746)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1291	Shared Neighborhood Hits	221
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MSH4_HUMAN
θ value	5.27518 (rank : 893)	NC score	0.004928 (rank : 1412)
Query Neighborhood Hits	1041	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	O15457, Q8NEB3, Q9UNP8	Gene names	MSH4
Domain Architecture
Description	MutS protein homolog 4.

MTR1L_HUMAN
θ value	5.27518 (rank : 894)	NC score	-0.012932 (rank : 1483)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1180	Shared Neighborhood Hits	76
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

MTSS1_MOUSE
θ value	5.27518 (rank : 895)	NC score	0.048780 (rank : 1139)
Query Neighborhood Hits	1041	Target Neighborhood Hits	592	Shared Neighborhood Hits	140
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NFIP2_HUMAN
θ value	5.27518 (rank : 896)	NC score	0.018254 (rank : 1328)
Query Neighborhood Hits	1041	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

PK1L1_HUMAN
θ value	5.27518 (rank : 897)	NC score	0.017817 (rank : 1331)
Query Neighborhood Hits	1041	Target Neighborhood Hits	140	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PTN3_HUMAN
θ value	5.27518 (rank : 898)	NC score	0.033532 (rank : 1239)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	101
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

RTN1_HUMAN
θ value	5.27518 (rank : 899)	NC score	0.036134 (rank : 1223)
Query Neighborhood Hits	1041	Target Neighborhood Hits	173	Shared Neighborhood Hits	52
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

RTN4_HUMAN
θ value	5.27518 (rank : 900)	NC score	0.057697 (rank : 980)
Query Neighborhood Hits	1041	Target Neighborhood Hits	357	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SALL1_MOUSE
θ value	5.27518 (rank : 901)	NC score	-0.005266 (rank : 1460)
Query Neighborhood Hits	1041	Target Neighborhood Hits	826	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

SC24A_MOUSE
θ value	5.27518 (rank : 902)	NC score	0.052047 (rank : 1084)
Query Neighborhood Hits	1041	Target Neighborhood Hits	394	Shared Neighborhood Hits	109
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SH3G1_HUMAN
θ value	5.27518 (rank : 903)	NC score	0.136418 (rank : 465)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	136
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SLY_HUMAN
θ value	5.27518 (rank : 904)	NC score	0.062799 (rank : 888)
Query Neighborhood Hits	1041	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SON_MOUSE
θ value	5.27518 (rank : 905)	NC score	0.092767 (rank : 634)
Query Neighborhood Hits	1041	Target Neighborhood Hits	957	Shared Neighborhood Hits	205
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRBP1_HUMAN
θ value	5.27518 (rank : 906)	NC score	0.043681 (rank : 1173)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TENS4_MOUSE
θ value	5.27518 (rank : 907)	NC score	0.047813 (rank : 1147)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

TPO_MOUSE
θ value	5.27518 (rank : 908)	NC score	0.021495 (rank : 1313)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TRS85_HUMAN
θ value	5.27518 (rank : 909)	NC score	0.009771 (rank : 1365)
Query Neighborhood Hits	1041	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2L5, Q9H0L2	Gene names	KIAA1012
Domain Architecture	No domain graphic available
Description	Protein TRS85 homolog.

TXLNB_MOUSE
θ value	5.27518 (rank : 910)	NC score	0.043660 (rank : 1174)
Query Neighborhood Hits	1041	Target Neighborhood Hits	640	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

VGLL2_MOUSE
θ value	5.27518 (rank : 911)	NC score	0.009355 (rank : 1373)
Query Neighborhood Hits	1041	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGW8, Q8BWB4	Gene names	Vgll2, Vgl2, Vito1
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 2 (Vgl-2) (Protein VITO1).

WASIP_HUMAN
θ value	5.27518 (rank : 912)	NC score	0.170585 (rank : 383)
Query Neighborhood Hits	1041	Target Neighborhood Hits	458	Shared Neighborhood Hits	207
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

XRCC1_MOUSE
θ value	5.27518 (rank : 913)	NC score	0.030415 (rank : 1253)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	51
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZBT7A_HUMAN
θ value	5.27518 (rank : 914)	NC score	-0.013543 (rank : 1484)
Query Neighborhood Hits	1041	Target Neighborhood Hits	823	Shared Neighborhood Hits	36
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).

ZCHC5_HUMAN
θ value	5.27518 (rank : 915)	NC score	0.037124 (rank : 1217)
Query Neighborhood Hits	1041	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

ZIM10_HUMAN
θ value	5.27518 (rank : 916)	NC score	0.044748 (rank : 1165)
Query Neighborhood Hits	1041	Target Neighborhood Hits	577	Shared Neighborhood Hits	125
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZO1_MOUSE
θ value	5.27518 (rank : 917)	NC score	0.126097 (rank : 508)
Query Neighborhood Hits	1041	Target Neighborhood Hits	453	Shared Neighborhood Hits	201
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ADA2C_MOUSE
θ value	6.88961 (rank : 918)	NC score	-0.015793 (rank : 1486)
Query Neighborhood Hits	1041	Target Neighborhood Hits	792	Shared Neighborhood Hits	11
SwissProt Accessions	Q01337	Gene names	Adra2c
Domain Architecture
Description	Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2C adrenoreceptor) (Alpha-2 adrenergic receptor subtype C4).

ASB14_HUMAN
θ value	6.88961 (rank : 919)	NC score	0.466538 (rank : 223)
Query Neighborhood Hits	1041	Target Neighborhood Hits	187	Shared Neighborhood Hits	170
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

AT8B1_HUMAN
θ value	6.88961 (rank : 920)	NC score	0.000858 (rank : 1438)
Query Neighborhood Hits	1041	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	O43520, Q9BTP8	Gene names	ATP8B1, ATPIC, FIC1, PFIC
Domain Architecture
Description	Probable phospholipid-transporting ATPase IC (EC 3.6.3.1) (Familial intrahepatic cholestasis type 1) (ATPase class I type 8B member 1).

AT8B3_HUMAN
θ value	6.88961 (rank : 921)	NC score	0.001597 (rank : 1432)
Query Neighborhood Hits	1041	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	O60423, Q8IVB8, Q8N4Y8, Q96M22	Gene names	ATP8B3, ATP1K, FOS37502_2
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IK (EC 3.6.3.1) (ATPase class I type 8B member 3).

ATF6B_HUMAN
θ value	6.88961 (rank : 922)	NC score	0.014883 (rank : 1347)
Query Neighborhood Hits	1041	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

BAZ2A_MOUSE
θ value	6.88961 (rank : 923)	NC score	0.040097 (rank : 1192)
Query Neighborhood Hits	1041	Target Neighborhood Hits	744	Shared Neighborhood Hits	141
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BCAR1_MOUSE
θ value	6.88961 (rank : 924)	NC score	0.134154 (rank : 474)
Query Neighborhood Hits	1041	Target Neighborhood Hits	438	Shared Neighborhood Hits	195
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CABIN_HUMAN
θ value	6.88961 (rank : 925)	NC score	0.073142 (rank : 770)
Query Neighborhood Hits	1041	Target Neighborhood Hits	490	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CECR2_HUMAN
θ value	6.88961 (rank : 926)	NC score	0.039744 (rank : 1195)
Query Neighborhood Hits	1041	Target Neighborhood Hits	543	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CING_HUMAN
θ value	6.88961 (rank : 927)	NC score	0.036578 (rank : 1221)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1275	Shared Neighborhood Hits	114
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CK024_HUMAN
θ value	6.88961 (rank : 928)	NC score	0.091912 (rank : 640)
Query Neighborhood Hits	1041	Target Neighborhood Hits	408	Shared Neighborhood Hits	125
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CNKR1_HUMAN
θ value	6.88961 (rank : 929)	NC score	0.064637 (rank : 856)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	56
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CRSP7_HUMAN
θ value	6.88961 (rank : 930)	NC score	0.032312 (rank : 1244)
Query Neighborhood Hits	1041	Target Neighborhood Hits	247	Shared Neighborhood Hits	66
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CSKP_MOUSE
θ value	6.88961 (rank : 931)	NC score	0.048643 (rank : 1140)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1027	Shared Neighborhood Hits	209
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CT012_HUMAN
θ value	6.88961 (rank : 932)	NC score	0.341839 (rank : 266)
Query Neighborhood Hits	1041	Target Neighborhood Hits	205	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DCP1B_HUMAN
θ value	6.88961 (rank : 933)	NC score	0.022575 (rank : 1306)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

DREB_HUMAN
θ value	6.88961 (rank : 934)	NC score	0.033143 (rank : 1242)
Query Neighborhood Hits	1041	Target Neighborhood Hits	450	Shared Neighborhood Hits	75
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

E2F4_HUMAN
θ value	6.88961 (rank : 935)	NC score	0.016271 (rank : 1341)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	48
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

EPN1_HUMAN
θ value	6.88961 (rank : 936)	NC score	0.064338 (rank : 861)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

FBSH_MOUSE
θ value	6.88961 (rank : 937)	NC score	0.035916 (rank : 1227)
Query Neighborhood Hits	1041	Target Neighborhood Hits	52	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R089	Gene names	Fbs1, Fbs
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

FGD3_HUMAN
θ value	6.88961 (rank : 938)	NC score	0.057166 (rank : 989)
Query Neighborhood Hits	1041	Target Neighborhood Hits	249	Shared Neighborhood Hits	61
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FLI1_HUMAN
θ value	6.88961 (rank : 939)	NC score	0.002637 (rank : 1425)
Query Neighborhood Hits	1041	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q01543, Q14319, Q92480, Q9UE07	Gene names	FLI1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Fli-1 proto- oncogene) (ERGB transcription factor).

FOXJ1_MOUSE
θ value	6.88961 (rank : 940)	NC score	0.003095 (rank : 1420)
Query Neighborhood Hits	1041	Target Neighborhood Hits	209	Shared Neighborhood Hits	32
SwissProt Accessions	Q61660	Gene names	Foxj1, Fkhl13, Hfh4
Domain Architecture
Description	Forkhead box protein J1 (Forkhead-related protein FKHL13) (Hepatocyte nuclear factor 3 forkhead homolog 4) (HFH-4).

GLI1_MOUSE
θ value	6.88961 (rank : 941)	NC score	-0.009733 (rank : 1470)
Query Neighborhood Hits	1041	Target Neighborhood Hits	785	Shared Neighborhood Hits	62
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

GLIS1_HUMAN
θ value	6.88961 (rank : 942)	NC score	-0.010143 (rank : 1471)
Query Neighborhood Hits	1041	Target Neighborhood Hits	748	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

HTRA3_MOUSE
θ value	6.88961 (rank : 943)	NC score	0.034063 (rank : 1235)
Query Neighborhood Hits	1041	Target Neighborhood Hits	156	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HUWE1_HUMAN
θ value	6.88961 (rank : 944)	NC score	0.016121 (rank : 1342)
Query Neighborhood Hits	1041	Target Neighborhood Hits	443	Shared Neighborhood Hits	77
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

IF4B_MOUSE
θ value	6.88961 (rank : 945)	NC score	0.026401 (rank : 1280)
Query Neighborhood Hits	1041	Target Neighborhood Hits	368	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IRS2_MOUSE
θ value	6.88961 (rank : 946)	NC score	0.041935 (rank : 1183)
Query Neighborhood Hits	1041	Target Neighborhood Hits	248	Shared Neighborhood Hits	102
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

KCD18_HUMAN
θ value	6.88961 (rank : 947)	NC score	0.009129 (rank : 1379)
Query Neighborhood Hits	1041	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

KI13B_HUMAN
θ value	6.88961 (rank : 948)	NC score	0.009419 (rank : 1372)
Query Neighborhood Hits	1041	Target Neighborhood Hits	492	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

LAP2_HUMAN
θ value	6.88961 (rank : 949)	NC score	0.045447 (rank : 1160)
Query Neighborhood Hits	1041	Target Neighborhood Hits	499	Shared Neighborhood Hits	114
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LARP4_MOUSE
θ value	6.88961 (rank : 950)	NC score	0.036579 (rank : 1220)
Query Neighborhood Hits	1041	Target Neighborhood Hits	260	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LIMD1_MOUSE
θ value	6.88961 (rank : 951)	NC score	0.021353 (rank : 1315)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

LIRB4_HUMAN
θ value	6.88961 (rank : 952)	NC score	-0.001757 (rank : 1450)
Query Neighborhood Hits	1041	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

MDFI_HUMAN
θ value	6.88961 (rank : 953)	NC score	0.015243 (rank : 1345)
Query Neighborhood Hits	1041	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q99750	Gene names	MDFI
Domain Architecture	No domain graphic available
Description	MyoD family inhibitor (Myogenic repressor I-mf).

MEGF9_MOUSE
θ value	6.88961 (rank : 954)	NC score	0.059866 (rank : 941)
Query Neighborhood Hits	1041	Target Neighborhood Hits	896	Shared Neighborhood Hits	149
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MICA1_HUMAN
θ value	6.88961 (rank : 955)	NC score	0.007189 (rank : 1395)
Query Neighborhood Hits	1041	Target Neighborhood Hits	279	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MKL2_MOUSE
θ value	6.88961 (rank : 956)	NC score	0.023481 (rank : 1298)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	58
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

PAPOB_HUMAN
θ value	6.88961 (rank : 957)	NC score	0.002175 (rank : 1431)
Query Neighborhood Hits	1041	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRJ5, Q8NE14	Gene names	PAPOLB, PAPT
Domain Architecture
Description	Poly(A) polymerase beta (EC 2.7.7.19) (PAP beta) (Polynucleotide adenylyltransferase beta) (Testis-specific poly(A) polymerase).

PCNT_HUMAN
θ value	6.88961 (rank : 958)	NC score	0.044232 (rank : 1168)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1551	Shared Neighborhood Hits	151
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PGCB_HUMAN
θ value	6.88961 (rank : 959)	NC score	0.036966 (rank : 1218)
Query Neighborhood Hits	1041	Target Neighborhood Hits	478	Shared Neighborhood Hits	72
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PKHG4_HUMAN
θ value	6.88961 (rank : 960)	NC score	0.056098 (rank : 1008)
Query Neighborhood Hits	1041	Target Neighborhood Hits	200	Shared Neighborhood Hits	58
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PO3F4_MOUSE
θ value	6.88961 (rank : 961)	NC score	0.000537 (rank : 1440)
Query Neighborhood Hits	1041	Target Neighborhood Hits	281	Shared Neighborhood Hits	19
SwissProt Accessions	P62515, P25216	Gene names	Pou3f4, Brn-4, Brn4, Otf9
Domain Architecture	No domain graphic available
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

PRGR_HUMAN
θ value	6.88961 (rank : 962)	NC score	0.002640 (rank : 1424)
Query Neighborhood Hits	1041	Target Neighborhood Hits	163	Shared Neighborhood Hits	24
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PSMF1_HUMAN
θ value	6.88961 (rank : 963)	NC score	0.009577 (rank : 1368)
Query Neighborhood Hits	1041	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q92530, Q9H4I1	Gene names	PSMF1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit (hPI31).

PYGO1_MOUSE
θ value	6.88961 (rank : 964)	NC score	0.012596 (rank : 1353)
Query Neighborhood Hits	1041	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D0P5	Gene names	Pygo1
Domain Architecture
Description	Pygopus homolog 1.

RC3H1_HUMAN
θ value	6.88961 (rank : 965)	NC score	0.018834 (rank : 1324)
Query Neighborhood Hits	1041	Target Neighborhood Hits	433	Shared Neighborhood Hits	78
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RPGF1_HUMAN
θ value	6.88961 (rank : 966)	NC score	0.017585 (rank : 1334)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	60
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SALL2_HUMAN
θ value	6.88961 (rank : 967)	NC score	-0.004459 (rank : 1459)
Query Neighborhood Hits	1041	Target Neighborhood Hits	835	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

SCNND_HUMAN
θ value	6.88961 (rank : 968)	NC score	0.002417 (rank : 1428)
Query Neighborhood Hits	1041	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P51172, Q5T7L3, Q8NA24	Gene names	SCNN1D, DNACH
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit delta (Epithelial Na+ channel subunit delta) (Delta ENaC) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED) (Delta NaCH).

SEM6C_MOUSE
θ value	6.88961 (rank : 969)	NC score	0.009828 (rank : 1364)
Query Neighborhood Hits	1041	Target Neighborhood Hits	352	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SFPQ_HUMAN
θ value	6.88961 (rank : 970)	NC score	0.093253 (rank : 630)
Query Neighborhood Hits	1041	Target Neighborhood Hits	986	Shared Neighborhood Hits	265
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SH3G3_HUMAN
θ value	6.88961 (rank : 971)	NC score	0.132699 (rank : 479)
Query Neighborhood Hits	1041	Target Neighborhood Hits	222	Shared Neighborhood Hits	121
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SORC2_HUMAN
θ value	6.88961 (rank : 972)	NC score	0.008883 (rank : 1382)
Query Neighborhood Hits	1041	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

SRMS_HUMAN
θ value	6.88961 (rank : 973)	NC score	0.051050 (rank : 1107)
Query Neighborhood Hits	1041	Target Neighborhood Hits	946	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SYNG_MOUSE
θ value	6.88961 (rank : 974)	NC score	0.026322 (rank : 1281)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TAF6L_MOUSE
θ value	6.88961 (rank : 975)	NC score	0.017072 (rank : 1338)
Query Neighborhood Hits	1041	Target Neighborhood Hits	146	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TCF7_MOUSE
θ value	6.88961 (rank : 976)	NC score	0.009162 (rank : 1377)
Query Neighborhood Hits	1041	Target Neighborhood Hits	277	Shared Neighborhood Hits	42
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TEC_HUMAN
θ value	6.88961 (rank : 977)	NC score	0.062111 (rank : 899)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1006	Shared Neighborhood Hits	149
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TF65_HUMAN
θ value	6.88961 (rank : 978)	NC score	0.057890 (rank : 977)
Query Neighborhood Hits	1041	Target Neighborhood Hits	115	Shared Neighborhood Hits	40
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TJAP1_MOUSE
θ value	6.88961 (rank : 979)	NC score	0.021892 (rank : 1311)
Query Neighborhood Hits	1041	Target Neighborhood Hits	295	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TM55A_HUMAN
θ value	6.88961 (rank : 980)	NC score	0.004934 (rank : 1411)
Query Neighborhood Hits	1041	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4L2, Q68CU2	Gene names	TMEM55A
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55A (EC 3.1.3.-) (Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase II).

TMPS9_MOUSE
θ value	6.88961 (rank : 981)	NC score	-0.009137 (rank : 1469)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	20
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TNIK_HUMAN
θ value	6.88961 (rank : 982)	NC score	0.030321 (rank : 1254)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1570	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TTLL5_HUMAN
θ value	6.88961 (rank : 983)	NC score	0.007593 (rank : 1393)
Query Neighborhood Hits	1041	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

ZIC1_MOUSE
θ value	6.88961 (rank : 984)	NC score	-0.012602 (rank : 1481)
Query Neighborhood Hits	1041	Target Neighborhood Hits	716	Shared Neighborhood Hits	37
SwissProt Accessions	P46684	Gene names	Zic1, Zic
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1).

ZIM10_MOUSE
θ value	6.88961 (rank : 985)	NC score	0.046173 (rank : 1157)
Query Neighborhood Hits	1041	Target Neighborhood Hits	430	Shared Neighborhood Hits	109
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZO2_MOUSE
θ value	6.88961 (rank : 986)	NC score	0.111585 (rank : 551)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

AMPH_HUMAN
θ value	8.99809 (rank : 987)	NC score	0.079873 (rank : 715)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	135
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ANDR_MOUSE
θ value	8.99809 (rank : 988)	NC score	-0.001021 (rank : 1446)
Query Neighborhood Hits	1041	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ARHG4_HUMAN
θ value	8.99809 (rank : 989)	NC score	0.142442 (rank : 448)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

AXN2_MOUSE
θ value	8.99809 (rank : 990)	NC score	0.009207 (rank : 1375)
Query Neighborhood Hits	1041	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

BAP1_MOUSE
θ value	8.99809 (rank : 991)	NC score	0.011408 (rank : 1356)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

BMP3B_HUMAN
θ value	8.99809 (rank : 992)	NC score	-0.002320 (rank : 1453)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	P55107, Q9UCX6	Gene names	GDF10, BMP3B
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10) (Bone-inducing protein) (BIP).

BNC2_HUMAN
θ value	8.99809 (rank : 993)	NC score	0.005547 (rank : 1409)
Query Neighborhood Hits	1041	Target Neighborhood Hits	439	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

C1QA_HUMAN
θ value	8.99809 (rank : 994)	NC score	0.005678 (rank : 1407)
Query Neighborhood Hits	1041	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

CAC1B_MOUSE
θ value	8.99809 (rank : 995)	NC score	0.008417 (rank : 1386)
Query Neighborhood Hits	1041	Target Neighborhood Hits	351	Shared Neighborhood Hits	75
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAD15_MOUSE
θ value	8.99809 (rank : 996)	NC score	-0.005362 (rank : 1462)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	P33146, Q9QYZ7	Gene names	Cdh15, Cdh14
Domain Architecture
Description	Cadherin-15 precursor (Muscle-cadherin) (M-cadherin) (Cadherin-14).

CDT1_HUMAN
θ value	8.99809 (rank : 997)	NC score	0.022137 (rank : 1308)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

CN004_HUMAN
θ value	8.99809 (rank : 998)	NC score	0.027271 (rank : 1274)
Query Neighborhood Hits	1041	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

CN004_MOUSE
θ value	8.99809 (rank : 999)	NC score	0.027813 (rank : 1270)
Query Neighborhood Hits	1041	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

CO1A2_MOUSE
θ value	8.99809 (rank : 1000)	NC score	0.044274 (rank : 1167)
Query Neighborhood Hits	1041	Target Neighborhood Hits	388	Shared Neighborhood Hits	110
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A1_MOUSE
θ value	8.99809 (rank : 1001)	NC score	0.037920 (rank : 1214)
Query Neighborhood Hits	1041	Target Neighborhood Hits	450	Shared Neighborhood Hits	128
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

DCX_HUMAN
θ value	8.99809 (rank : 1002)	NC score	0.009193 (rank : 1376)
Query Neighborhood Hits	1041	Target Neighborhood Hits	141	Shared Neighborhood Hits	32
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

DGKQ_HUMAN
θ value	8.99809 (rank : 1003)	NC score	0.036074 (rank : 1224)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

DLGP4_HUMAN
θ value	8.99809 (rank : 1004)	NC score	0.007167 (rank : 1396)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

DLX4_MOUSE
θ value	8.99809 (rank : 1005)	NC score	-0.002403 (rank : 1454)
Query Neighborhood Hits	1041	Target Neighborhood Hits	352	Shared Neighborhood Hits	22
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

EPHA7_HUMAN
θ value	8.99809 (rank : 1006)	NC score	0.046312 (rank : 1156)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1053	Shared Neighborhood Hits	95
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

ERRFI_MOUSE
θ value	8.99809 (rank : 1007)	NC score	0.022787 (rank : 1304)
Query Neighborhood Hits	1041	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

FOXI1_MOUSE
θ value	8.99809 (rank : 1008)	NC score	0.001310 (rank : 1434)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	Q922I5, Q5SRI5, Q9D299	Gene names	Foxi1
Domain Architecture	No domain graphic available
Description	Forkhead box protein I1.

FOXQ1_MOUSE
θ value	8.99809 (rank : 1009)	NC score	0.002361 (rank : 1429)
Query Neighborhood Hits	1041	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	O70220	Gene names	Foxq1, Hfh1, Hfh1l
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1) (HFH-1l).

GOGA3_MOUSE
θ value	8.99809 (rank : 1010)	NC score	0.046859 (rank : 1154)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1437	Shared Neighborhood Hits	117
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GP123_HUMAN
θ value	8.99809 (rank : 1011)	NC score	0.005980 (rank : 1404)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

HTRA1_HUMAN
θ value	8.99809 (rank : 1012)	NC score	0.027515 (rank : 1273)
Query Neighborhood Hits	1041	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

IL4RA_MOUSE
θ value	8.99809 (rank : 1013)	NC score	0.024917 (rank : 1285)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	52
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

IRF7_HUMAN
θ value	8.99809 (rank : 1014)	NC score	0.004417 (rank : 1415)
Query Neighborhood Hits	1041	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

K0562_MOUSE
θ value	8.99809 (rank : 1015)	NC score	0.011322 (rank : 1357)
Query Neighborhood Hits	1041	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

K1543_HUMAN
θ value	8.99809 (rank : 1016)	NC score	0.064394 (rank : 858)
Query Neighborhood Hits	1041	Target Neighborhood Hits	435	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAZ_MOUSE
θ value	8.99809 (rank : 1017)	NC score	-0.011172 (rank : 1475)
Query Neighborhood Hits	1041	Target Neighborhood Hits	745	Shared Neighborhood Hits	52
SwissProt Accessions	P56671, Q9R1W0	Gene names	Maz
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1).

MSX1_HUMAN
θ value	8.99809 (rank : 1018)	NC score	-0.001217 (rank : 1447)
Query Neighborhood Hits	1041	Target Neighborhood Hits	374	Shared Neighborhood Hits	28
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

MUC5B_HUMAN
θ value	8.99809 (rank : 1019)	NC score	0.073535 (rank : 766)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1020	Shared Neighborhood Hits	183
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYPN_MOUSE
θ value	8.99809 (rank : 1020)	NC score	0.007098 (rank : 1397)
Query Neighborhood Hits	1041	Target Neighborhood Hits	421	Shared Neighborhood Hits	45
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NEBU_HUMAN
θ value	8.99809 (rank : 1021)	NC score	0.089350 (rank : 653)
Query Neighborhood Hits	1041	Target Neighborhood Hits	420	Shared Neighborhood Hits	128
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NSD1_HUMAN
θ value	8.99809 (rank : 1022)	NC score	0.047920 (rank : 1146)
Query Neighborhood Hits	1041	Target Neighborhood Hits	427	Shared Neighborhood Hits	83
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

OBF1_HUMAN
θ value	8.99809 (rank : 1023)	NC score	0.027988 (rank : 1268)
Query Neighborhood Hits	1041	Target Neighborhood Hits	203	Shared Neighborhood Hits	57
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PCIF1_HUMAN
θ value	8.99809 (rank : 1024)	NC score	0.006005 (rank : 1403)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

PER2_MOUSE
θ value	8.99809 (rank : 1025)	NC score	0.013222 (rank : 1352)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	56
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PR285_HUMAN
θ value	8.99809 (rank : 1026)	NC score	0.002282 (rank : 1430)
Query Neighborhood Hits	1041	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

RBBP7_HUMAN
θ value	8.99809 (rank : 1027)	NC score	-0.008163 (rank : 1466)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
θ value	8.99809 (rank : 1028)	NC score	-0.008175 (rank : 1467)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RIMS1_HUMAN
θ value	8.99809 (rank : 1029)	NC score	0.066493 (rank : 842)
Query Neighborhood Hits	1041	Target Neighborhood Hits	437	Shared Neighborhood Hits	138
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RX_MOUSE
θ value	8.99809 (rank : 1030)	NC score	-0.000140 (rank : 1442)
Query Neighborhood Hits	1041	Target Neighborhood Hits	429	Shared Neighborhood Hits	41
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SH3G1_MOUSE
θ value	8.99809 (rank : 1031)	NC score	0.134450 (rank : 473)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	137
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SNIP_MOUSE
θ value	8.99809 (rank : 1032)	NC score	0.038886 (rank : 1204)
Query Neighborhood Hits	1041	Target Neighborhood Hits	319	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SYNE1_HUMAN
θ value	8.99809 (rank : 1033)	NC score	0.028483 (rank : 1267)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1484	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TARSH_HUMAN
θ value	8.99809 (rank : 1034)	NC score	0.092045 (rank : 639)
Query Neighborhood Hits	1041	Target Neighborhood Hits	768	Shared Neighborhood Hits	186
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TCF7_HUMAN
θ value	8.99809 (rank : 1035)	NC score	0.006116 (rank : 1401)
Query Neighborhood Hits	1041	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TTLL4_HUMAN
θ value	8.99809 (rank : 1036)	NC score	0.004770 (rank : 1413)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

TTLL5_MOUSE
θ value	8.99809 (rank : 1037)	NC score	0.009660 (rank : 1367)
Query Neighborhood Hits	1041	Target Neighborhood Hits	150	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

WNK1_MOUSE
θ value	8.99809 (rank : 1038)	NC score	0.045569 (rank : 1159)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1179	Shared Neighborhood Hits	158
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ZEP2_HUMAN
θ value	8.99809 (rank : 1039)	NC score	-0.001220 (rank : 1448)
Query Neighborhood Hits	1041	Target Neighborhood Hits	937	Shared Neighborhood Hits	96
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZEP2_MOUSE
θ value	8.99809 (rank : 1040)	NC score	-0.000232 (rank : 1444)
Query Neighborhood Hits	1041	Target Neighborhood Hits	964	Shared Neighborhood Hits	103
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ZN207_HUMAN
θ value	8.99809 (rank : 1041)	NC score	0.105607 (rank : 571)
Query Neighborhood Hits	1041	Target Neighborhood Hits	326	Shared Neighborhood Hits	98
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

3BP1_HUMAN
θ value	θ > 10 (rank : 1042)	NC score	0.062989 (rank : 881)
Query Neighborhood Hits	1041	Target Neighborhood Hits	376	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ABI3_HUMAN
θ value	θ > 10 (rank : 1043)	NC score	0.135157 (rank : 470)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	144
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 1044)	NC score	0.131402 (rank : 488)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	150
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABTB1_HUMAN
θ value	θ > 10 (rank : 1045)	NC score	0.209006 (rank : 323)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	158
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 1046)	NC score	0.242629 (rank : 292)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	171
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ACINU_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.050107 (rank : 1130)
Query Neighborhood Hits	1041	Target Neighborhood Hits	828	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 1048)	NC score	0.062822 (rank : 885)
Query Neighborhood Hits	1041	Target Neighborhood Hits	712	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF1_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.070991 (rank : 791)
Query Neighborhood Hits	1041	Target Neighborhood Hits	506	Shared Neighborhood Hits	134
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF1_MOUSE
θ value	θ > 10 (rank : 1050)	NC score	0.059764 (rank : 944)
Query Neighborhood Hits	1041	Target Neighborhood Hits	351	Shared Neighborhood Hits	104
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AGRIN_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.051623 (rank : 1095)
Query Neighborhood Hits	1041	Target Neighborhood Hits	582	Shared Neighborhood Hits	59
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

AHI1_HUMAN
θ value	θ > 10 (rank : 1052)	NC score	0.104752 (rank : 575)
Query Neighborhood Hits	1041	Target Neighborhood Hits	537	Shared Neighborhood Hits	145
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
θ value	θ > 10 (rank : 1053)	NC score	0.099226 (rank : 602)
Query Neighborhood Hits	1041	Target Neighborhood Hits	496	Shared Neighborhood Hits	144
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ALEX_HUMAN
θ value	θ > 10 (rank : 1054)	NC score	0.083193 (rank : 683)
Query Neighborhood Hits	1041	Target Neighborhood Hits	361	Shared Neighborhood Hits	137
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALEX_MOUSE
θ value	θ > 10 (rank : 1055)	NC score	0.051309 (rank : 1103)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	81
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AMOT_HUMAN
θ value	θ > 10 (rank : 1056)	NC score	0.057069 (rank : 994)
Query Neighborhood Hits	1041	Target Neighborhood Hits	712	Shared Neighborhood Hits	134
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ANKF1_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.108366 (rank : 563)
Query Neighborhood Hits	1041	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANR38_HUMAN
θ value	θ > 10 (rank : 1058)	NC score	0.553407 (rank : 190)
Query Neighborhood Hits	1041	Target Neighborhood Hits	443	Shared Neighborhood Hits	260
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR43_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.497814 (rank : 210)
Query Neighborhood Hits	1041	Target Neighborhood Hits	209	Shared Neighborhood Hits	197
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_MOUSE
θ value	θ > 10 (rank : 1060)	NC score	0.488722 (rank : 212)
Query Neighborhood Hits	1041	Target Neighborhood Hits	214	Shared Neighborhood Hits	200
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

AP180_MOUSE
θ value	θ > 10 (rank : 1061)	NC score	0.050555 (rank : 1118)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	74
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

APS_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.051910 (rank : 1087)
Query Neighborhood Hits	1041	Target Neighborhood Hits	162	Shared Neighborhood Hits	55
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

ARFG1_HUMAN
θ value	θ > 10 (rank : 1063)	NC score	0.051859 (rank : 1088)
Query Neighborhood Hits	1041	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_MOUSE
θ value	θ > 10 (rank : 1064)	NC score	0.051451 (rank : 1098)
Query Neighborhood Hits	1041	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
θ value	θ > 10 (rank : 1065)	NC score	0.051108 (rank : 1106)
Query Neighborhood Hits	1041	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 1066)	NC score	0.052073 (rank : 1082)
Query Neighborhood Hits	1041	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARHG1_HUMAN
θ value	θ > 10 (rank : 1067)	NC score	0.081828 (rank : 701)
Query Neighborhood Hits	1041	Target Neighborhood Hits	176	Shared Neighborhood Hits	56
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 1068)	NC score	0.085171 (rank : 668)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	88
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 1069)	NC score	0.062319 (rank : 896)
Query Neighborhood Hits	1041	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 1070)	NC score	0.059784 (rank : 943)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	37
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 1071)	NC score	0.082003 (rank : 698)
Query Neighborhood Hits	1041	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 1072)	NC score	0.082100 (rank : 695)
Query Neighborhood Hits	1041	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_MOUSE
θ value	θ > 10 (rank : 1073)	NC score	0.127711 (rank : 502)
Query Neighborhood Hits	1041	Target Neighborhood Hits	185	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG8_HUMAN
θ value	θ > 10 (rank : 1074)	NC score	0.072999 (rank : 773)
Query Neighborhood Hits	1041	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 1075)	NC score	0.080562 (rank : 709)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGA_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.066708 (rank : 840)
Query Neighborhood Hits	1041	Target Neighborhood Hits	187	Shared Neighborhood Hits	46
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 1077)	NC score	0.060414 (rank : 929)
Query Neighborhood Hits	1041	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGF_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.086970 (rank : 660)
Query Neighborhood Hits	1041	Target Neighborhood Hits	214	Shared Neighborhood Hits	116
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.081357 (rank : 706)
Query Neighborhood Hits	1041	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ATX2_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.058910 (rank : 961)
Query Neighborhood Hits	1041	Target Neighborhood Hits	375	Shared Neighborhood Hits	122
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	θ > 10 (rank : 1081)	NC score	0.058147 (rank : 973)
Query Neighborhood Hits	1041	Target Neighborhood Hits	445	Shared Neighborhood Hits	133
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

AUTS2_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.052509 (rank : 1073)
Query Neighborhood Hits	1041	Target Neighborhood Hits	342	Shared Neighborhood Hits	114
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BASP_HUMAN
θ value	θ > 10 (rank : 1083)	NC score	0.102916 (rank : 582)
Query Neighborhood Hits	1041	Target Neighborhood Hits	321	Shared Neighborhood Hits	102
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 1084)	NC score	0.121199 (rank : 525)
Query Neighborhood Hits	1041	Target Neighborhood Hits	260	Shared Neighborhood Hits	94
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.067626 (rank : 831)
Query Neighborhood Hits	1041	Target Neighborhood Hits	490	Shared Neighborhood Hits	148
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	θ > 10 (rank : 1086)	NC score	0.074937 (rank : 754)
Query Neighborhood Hits	1041	Target Neighborhood Hits	518	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BAT4_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.192465 (rank : 341)
Query Neighborhood Hits	1041	Target Neighborhood Hits	157	Shared Neighborhood Hits	107
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.215418 (rank : 309)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	120
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BIN1_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.070873 (rank : 795)
Query Neighborhood Hits	1041	Target Neighborhood Hits	335	Shared Neighborhood Hits	125
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BLK_HUMAN
θ value	θ > 10 (rank : 1090)	NC score	0.063337 (rank : 875)
Query Neighborhood Hits	1041	Target Neighborhood Hits	994	Shared Neighborhood Hits	144
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 1091)	NC score	0.062878 (rank : 883)
Query Neighborhood Hits	1041	Target Neighborhood Hits	992	Shared Neighborhood Hits	139
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLNK_MOUSE
θ value	θ > 10 (rank : 1092)	NC score	0.064100 (rank : 864)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BRD4_HUMAN
θ value	θ > 10 (rank : 1093)	NC score	0.065368 (rank : 850)
Query Neighborhood Hits	1041	Target Neighborhood Hits	851	Shared Neighborhood Hits	216
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 1094)	NC score	0.076679 (rank : 737)
Query Neighborhood Hits	1041	Target Neighborhood Hits	845	Shared Neighborhood Hits	206
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BTK_HUMAN
θ value	θ > 10 (rank : 1095)	NC score	0.068574 (rank : 818)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1026	Shared Neighborhood Hits	172
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 1096)	NC score	0.067082 (rank : 835)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1017	Shared Neighborhood Hits	168
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CASL_HUMAN
θ value	θ > 10 (rank : 1097)	NC score	0.094238 (rank : 624)
Query Neighborhood Hits	1041	Target Neighborhood Hits	259	Shared Neighborhood Hits	130
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	θ > 10 (rank : 1098)	NC score	0.098677 (rank : 605)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	125
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CCD96_MOUSE
θ value	θ > 10 (rank : 1099)	NC score	0.052662 (rank : 1066)
Query Neighborhood Hits	1041	Target Neighborhood Hits	704	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCNK_MOUSE
θ value	θ > 10 (rank : 1100)	NC score	0.086805 (rank : 661)
Query Neighborhood Hits	1041	Target Neighborhood Hits	350	Shared Neighborhood Hits	157
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD2A1_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.500156 (rank : 208)
Query Neighborhood Hits	1041	Target Neighborhood Hits	196	Shared Neighborhood Hits	184
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CDN1C_HUMAN
θ value	θ > 10 (rank : 1102)	NC score	0.084156 (rank : 677)
Query Neighborhood Hits	1041	Target Neighborhood Hits	168	Shared Neighborhood Hits	86
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CDN2B_HUMAN
θ value	θ > 10 (rank : 1103)	NC score	0.503056 (rank : 206)
Query Neighborhood Hits	1041	Target Neighborhood Hits	196	Shared Neighborhood Hits	189
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CDN2B_MOUSE
θ value	θ > 10 (rank : 1104)	NC score	0.536675 (rank : 196)
Query Neighborhood Hits	1041	Target Neighborhood Hits	201	Shared Neighborhood Hits	192
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CENA1_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.056834 (rank : 998)
Query Neighborhood Hits	1041	Target Neighborhood Hits	87	Shared Neighborhood Hits	24
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 1106)	NC score	0.051490 (rank : 1097)
Query Neighborhood Hits	1041	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 1107)	NC score	0.052515 (rank : 1072)
Query Neighborhood Hits	1041	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND3_HUMAN
θ value	θ > 10 (rank : 1108)	NC score	0.062811 (rank : 886)
Query Neighborhood Hits	1041	Target Neighborhood Hits	275	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	θ > 10 (rank : 1109)	NC score	0.058368 (rank : 968)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CMTA1_HUMAN
θ value	θ > 10 (rank : 1110)	NC score	0.157691 (rank : 415)
Query Neighborhood Hits	1041	Target Neighborhood Hits	217	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	θ > 10 (rank : 1111)	NC score	0.132660 (rank : 480)
Query Neighborhood Hits	1041	Target Neighborhood Hits	199	Shared Neighborhood Hits	120
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	θ > 10 (rank : 1112)	NC score	0.125244 (rank : 513)
Query Neighborhood Hits	1041	Target Neighborhood Hits	216	Shared Neighborhood Hits	119
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CN032_MOUSE
θ value	θ > 10 (rank : 1113)	NC score	0.111731 (rank : 548)
Query Neighborhood Hits	1041	Target Neighborhood Hits	233	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 1114)	NC score	0.114109 (rank : 539)
Query Neighborhood Hits	1041	Target Neighborhood Hits	385	Shared Neighborhood Hits	133
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNOT3_HUMAN
θ value	θ > 10 (rank : 1115)	NC score	0.077494 (rank : 730)
Query Neighborhood Hits	1041	Target Neighborhood Hits	425	Shared Neighborhood Hits	139
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 1116)	NC score	0.074575 (rank : 759)
Query Neighborhood Hits	1041	Target Neighborhood Hits	504	Shared Neighborhood Hits	145
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO002_HUMAN
θ value	θ > 10 (rank : 1117)	NC score	0.050799 (rank : 1114)
Query Neighborhood Hits	1041	Target Neighborhood Hits	387	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO1A1_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.059832 (rank : 942)
Query Neighborhood Hits	1041	Target Neighborhood Hits	475	Shared Neighborhood Hits	153
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A1_MOUSE
θ value	θ > 10 (rank : 1119)	NC score	0.063186 (rank : 878)
Query Neighborhood Hits	1041	Target Neighborhood Hits	457	Shared Neighborhood Hits	152
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
θ value	θ > 10 (rank : 1120)	NC score	0.060575 (rank : 926)
Query Neighborhood Hits	1041	Target Neighborhood Hits	452	Shared Neighborhood Hits	143
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	θ > 10 (rank : 1121)	NC score	0.058825 (rank : 962)
Query Neighborhood Hits	1041	Target Neighborhood Hits	466	Shared Neighborhood Hits	146
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A5_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.058602 (rank : 965)
Query Neighborhood Hits	1041	Target Neighborhood Hits	383	Shared Neighborhood Hits	129
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

COGA1_HUMAN
θ value	θ > 10 (rank : 1123)	NC score	0.055132 (rank : 1025)
Query Neighborhood Hits	1041	Target Neighborhood Hits	345	Shared Neighborhood Hits	112
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

COHA1_HUMAN
θ value	θ > 10 (rank : 1124)	NC score	0.058242 (rank : 971)
Query Neighborhood Hits	1041	Target Neighborhood Hits	400	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COHA1_MOUSE
θ value	θ > 10 (rank : 1125)	NC score	0.050909 (rank : 1110)
Query Neighborhood Hits	1041	Target Neighborhood Hits	414	Shared Neighborhood Hits	128
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COIA1_HUMAN
θ value	θ > 10 (rank : 1126)	NC score	0.052783 (rank : 1064)
Query Neighborhood Hits	1041	Target Neighborhood Hits	447	Shared Neighborhood Hits	136
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CPSF6_HUMAN
θ value	θ > 10 (rank : 1127)	NC score	0.098837 (rank : 603)
Query Neighborhood Hits	1041	Target Neighborhood Hits	359	Shared Neighborhood Hits	152
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 1128)	NC score	0.100230 (rank : 598)
Query Neighborhood Hits	1041	Target Neighborhood Hits	356	Shared Neighborhood Hits	153
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRTC1_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.068477 (rank : 821)
Query Neighborhood Hits	1041	Target Neighborhood Hits	319	Shared Neighborhood Hits	136
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CRUM1_HUMAN
θ value	θ > 10 (rank : 1130)	NC score	0.059366 (rank : 952)
Query Neighborhood Hits	1041	Target Neighborhood Hits	457	Shared Neighborhood Hits	24
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 1131)	NC score	0.059238 (rank : 954)
Query Neighborhood Hits	1041	Target Neighborhood Hits	444	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 1132)	NC score	0.060294 (rank : 934)
Query Neighborhood Hits	1041	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CS007_MOUSE
θ value	θ > 10 (rank : 1133)	NC score	0.079550 (rank : 718)
Query Neighborhood Hits	1041	Target Neighborhood Hits	464	Shared Neighborhood Hits	152
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS016_HUMAN
θ value	θ > 10 (rank : 1134)	NC score	0.093818 (rank : 627)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	129
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSK_HUMAN
θ value	θ > 10 (rank : 1135)	NC score	0.061453 (rank : 909)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1009	Shared Neighborhood Hits	143
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 1136)	NC score	0.061038 (rank : 919)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1009	Shared Neighborhood Hits	143
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CSPG3_MOUSE
θ value	θ > 10 (rank : 1137)	NC score	0.050186 (rank : 1127)
Query Neighborhood Hits	1041	Target Neighborhood Hits	657	Shared Neighborhood Hits	83
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CT032_HUMAN
θ value	θ > 10 (rank : 1138)	NC score	0.115553 (rank : 537)
Query Neighborhood Hits	1041	Target Neighborhood Hits	235	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CT151_HUMAN
θ value	θ > 10 (rank : 1139)	NC score	0.052919 (rank : 1061)
Query Neighborhood Hits	1041	Target Neighborhood Hits	382	Shared Neighborhood Hits	96
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CT2NL_HUMAN
θ value	θ > 10 (rank : 1140)	NC score	0.055264 (rank : 1023)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1059	Shared Neighborhood Hits	123
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 1141)	NC score	0.051822 (rank : 1090)
Query Neighborhood Hits	1041	Target Neighborhood Hits	902	Shared Neighborhood Hits	114
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CU081_HUMAN
θ value	θ > 10 (rank : 1142)	NC score	0.088220 (rank : 656)
Query Neighborhood Hits	1041	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DAPP1_HUMAN
θ value	θ > 10 (rank : 1143)	NC score	0.067994 (rank : 828)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 1144)	NC score	0.068030 (rank : 827)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DBNL_HUMAN
θ value	θ > 10 (rank : 1145)	NC score	0.111633 (rank : 550)
Query Neighborhood Hits	1041	Target Neighborhood Hits	244	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 1146)	NC score	0.115682 (rank : 536)
Query Neighborhood Hits	1041	Target Neighborhood Hits	306	Shared Neighborhood Hits	127
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DGKK_HUMAN
θ value	θ > 10 (rank : 1147)	NC score	0.100391 (rank : 597)
Query Neighborhood Hits	1041	Target Neighborhood Hits	378	Shared Neighborhood Hits	140
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIAP1_HUMAN
θ value	θ > 10 (rank : 1148)	NC score	0.070543 (rank : 797)
Query Neighborhood Hits	1041	Target Neighborhood Hits	784	Shared Neighborhood Hits	184
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	θ > 10 (rank : 1149)	NC score	0.069167 (rank : 813)
Query Neighborhood Hits	1041	Target Neighborhood Hits	839	Shared Neighborhood Hits	164
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DLG2_MOUSE
θ value	θ > 10 (rank : 1150)	NC score	0.159012 (rank : 414)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	177
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLK_HUMAN
θ value	θ > 10 (rank : 1151)	NC score	0.052014 (rank : 1085)
Query Neighborhood Hits	1041	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 1152)	NC score	0.052530 (rank : 1070)
Query Neighborhood Hits	1041	Target Neighborhood Hits	374	Shared Neighborhood Hits	20
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 1153)	NC score	0.051986 (rank : 1086)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	26
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 1154)	NC score	0.051697 (rank : 1094)
Query Neighborhood Hits	1041	Target Neighborhood Hits	456	Shared Neighborhood Hits	24
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 1155)	NC score	0.054285 (rank : 1044)
Query Neighborhood Hits	1041	Target Neighborhood Hits	419	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 1156)	NC score	0.055346 (rank : 1021)
Query Neighborhood Hits	1041	Target Neighborhood Hits	399	Shared Neighborhood Hits	22
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 1157)	NC score	0.053115 (rank : 1059)
Query Neighborhood Hits	1041	Target Neighborhood Hits	435	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 1158)	NC score	0.054548 (rank : 1038)
Query Neighborhood Hits	1041	Target Neighborhood Hits	440	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 1159)	NC score	0.061515 (rank : 906)
Query Neighborhood Hits	1041	Target Neighborhood Hits	460	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 1160)	NC score	0.061911 (rank : 900)
Query Neighborhood Hits	1041	Target Neighborhood Hits	413	Shared Neighborhood Hits	28
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DOT1L_HUMAN
θ value	θ > 10 (rank : 1161)	NC score	0.074819 (rank : 756)
Query Neighborhood Hits	1041	Target Neighborhood Hits	660	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DVL1L_HUMAN
θ value	θ > 10 (rank : 1162)	NC score	0.060005 (rank : 940)
Query Neighborhood Hits	1041	Target Neighborhood Hits	146	Shared Neighborhood Hits	95
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	θ > 10 (rank : 1163)	NC score	0.064206 (rank : 862)
Query Neighborhood Hits	1041	Target Neighborhood Hits	158	Shared Neighborhood Hits	102
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	θ > 10 (rank : 1164)	NC score	0.060140 (rank : 938)
Query Neighborhood Hits	1041	Target Neighborhood Hits	146	Shared Neighborhood Hits	92
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL2_HUMAN
θ value	θ > 10 (rank : 1165)	NC score	0.072085 (rank : 781)
Query Neighborhood Hits	1041	Target Neighborhood Hits	223	Shared Neighborhood Hits	126
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	θ > 10 (rank : 1166)	NC score	0.068373 (rank : 822)
Query Neighborhood Hits	1041	Target Neighborhood Hits	233	Shared Neighborhood Hits	135
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	θ > 10 (rank : 1167)	NC score	0.061476 (rank : 907)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	99
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	θ > 10 (rank : 1168)	NC score	0.061752 (rank : 904)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	102
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

ECT2_HUMAN
θ value	θ > 10 (rank : 1169)	NC score	0.069474 (rank : 809)
Query Neighborhood Hits	1041	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 1170)	NC score	0.071863 (rank : 784)
Query Neighborhood Hits	1041	Target Neighborhood Hits	98	Shared Neighborhood Hits	34
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EFS_MOUSE
θ value	θ > 10 (rank : 1171)	NC score	0.127954 (rank : 501)
Query Neighborhood Hits	1041	Target Neighborhood Hits	389	Shared Neighborhood Hits	178
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

EGFL9_HUMAN
θ value	θ > 10 (rank : 1172)	NC score	0.057380 (rank : 986)
Query Neighborhood Hits	1041	Target Neighborhood Hits	365	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 1173)	NC score	0.057157 (rank : 990)
Query Neighborhood Hits	1041	Target Neighborhood Hits	379	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

ELN_HUMAN
θ value	θ > 10 (rank : 1174)	NC score	0.063673 (rank : 869)
Query Neighborhood Hits	1041	Target Neighborhood Hits	85	Shared Neighborhood Hits	34
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

ENAH_HUMAN
θ value	θ > 10 (rank : 1175)	NC score	0.061000 (rank : 920)
Query Neighborhood Hits	1041	Target Neighborhood Hits	784	Shared Neighborhood Hits	175
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 1176)	NC score	0.112876 (rank : 544)
Query Neighborhood Hits	1041	Target Neighborhood Hits	919	Shared Neighborhood Hits	253
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENL_HUMAN
θ value	θ > 10 (rank : 1177)	NC score	0.055927 (rank : 1010)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

EP15R_MOUSE
θ value	θ > 10 (rank : 1178)	NC score	0.051203 (rank : 1104)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1135	Shared Neighborhood Hits	129
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EPN1_MOUSE
θ value	θ > 10 (rank : 1179)	NC score	0.055794 (rank : 1013)
Query Neighborhood Hits	1041	Target Neighborhood Hits	240	Shared Neighborhood Hits	101
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

ES8L2_HUMAN
θ value	θ > 10 (rank : 1180)	NC score	0.053742 (rank : 1050)
Query Neighborhood Hits	1041	Target Neighborhood Hits	193	Shared Neighborhood Hits	95
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
θ value	θ > 10 (rank : 1181)	NC score	0.053205 (rank : 1055)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	91
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L3_MOUSE
θ value	θ > 10 (rank : 1182)	NC score	0.072562 (rank : 777)
Query Neighborhood Hits	1041	Target Neighborhood Hits	168	Shared Neighborhood Hits	101
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FA47A_HUMAN
θ value	θ > 10 (rank : 1183)	NC score	0.064348 (rank : 860)
Query Neighborhood Hits	1041	Target Neighborhood Hits	451	Shared Neighborhood Hits	104
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FBN1_HUMAN
θ value	θ > 10 (rank : 1184)	NC score	0.052214 (rank : 1080)
Query Neighborhood Hits	1041	Target Neighborhood Hits	557	Shared Neighborhood Hits	31
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 1185)	NC score	0.052405 (rank : 1075)
Query Neighborhood Hits	1041	Target Neighborhood Hits	563	Shared Neighborhood Hits	33
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 1186)	NC score	0.052517 (rank : 1071)
Query Neighborhood Hits	1041	Target Neighborhood Hits	560	Shared Neighborhood Hits	31
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 1187)	NC score	0.052288 (rank : 1079)
Query Neighborhood Hits	1041	Target Neighborhood Hits	549	Shared Neighborhood Hits	29
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 1188)	NC score	0.052970 (rank : 1060)
Query Neighborhood Hits	1041	Target Neighborhood Hits	543	Shared Neighborhood Hits	27
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FER_HUMAN
θ value	θ > 10 (rank : 1189)	NC score	0.051769 (rank : 1091)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1278	Shared Neighborhood Hits	129
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FGD1_HUMAN
θ value	θ > 10 (rank : 1190)	NC score	0.072004 (rank : 783)
Query Neighborhood Hits	1041	Target Neighborhood Hits	367	Shared Neighborhood Hits	132
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 1191)	NC score	0.069941 (rank : 804)
Query Neighborhood Hits	1041	Target Neighborhood Hits	387	Shared Neighborhood Hits	126
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 1192)	NC score	0.054044 (rank : 1046)
Query Neighborhood Hits	1041	Target Neighborhood Hits	151	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 1193)	NC score	0.054871 (rank : 1027)
Query Neighborhood Hits	1041	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_MOUSE
θ value	θ > 10 (rank : 1194)	NC score	0.058983 (rank : 960)
Query Neighborhood Hits	1041	Target Neighborhood Hits	257	Shared Neighborhood Hits	52
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 1195)	NC score	0.060192 (rank : 937)
Query Neighborhood Hits	1041	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 1196)	NC score	0.063461 (rank : 872)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FMN1A_MOUSE
θ value	θ > 10 (rank : 1197)	NC score	0.061780 (rank : 902)
Query Neighborhood Hits	1041	Target Neighborhood Hits	423	Shared Neighborhood Hits	149
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	θ > 10 (rank : 1198)	NC score	0.059096 (rank : 959)
Query Neighborhood Hits	1041	Target Neighborhood Hits	447	Shared Neighborhood Hits	150
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMNL_HUMAN
θ value	θ > 10 (rank : 1199)	NC score	0.076379 (rank : 741)
Query Neighborhood Hits	1041	Target Neighborhood Hits	529	Shared Neighborhood Hits	185
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FNBP2_HUMAN
θ value	θ > 10 (rank : 1200)	NC score	0.059688 (rank : 947)
Query Neighborhood Hits	1041	Target Neighborhood Hits	432	Shared Neighborhood Hits	128
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FYB_HUMAN
θ value	θ > 10 (rank : 1201)	NC score	0.062328 (rank : 895)
Query Neighborhood Hits	1041	Target Neighborhood Hits	379	Shared Neighborhood Hits	121
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GGN_HUMAN
θ value	θ > 10 (rank : 1202)	NC score	0.103306 (rank : 580)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	132
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 1203)	NC score	0.106917 (rank : 567)
Query Neighborhood Hits	1041	Target Neighborhood Hits	311	Shared Neighborhood Hits	144
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GLSK_HUMAN
θ value	θ > 10 (rank : 1204)	NC score	0.364442 (rank : 262)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	184
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GLSL_HUMAN
θ value	θ > 10 (rank : 1205)	NC score	0.399019 (rank : 250)
Query Neighborhood Hits	1041	Target Neighborhood Hits	211	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GLSL_MOUSE
θ value	θ > 10 (rank : 1206)	NC score	0.388097 (rank : 253)
Query Neighborhood Hits	1041	Target Neighborhood Hits	212	Shared Neighborhood Hits	194
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GNRP_MOUSE
θ value	θ > 10 (rank : 1207)	NC score	0.050157 (rank : 1129)
Query Neighborhood Hits	1041	Target Neighborhood Hits	191	Shared Neighborhood Hits	43
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GRIN1_MOUSE
θ value	θ > 10 (rank : 1208)	NC score	0.075307 (rank : 751)
Query Neighborhood Hits	1041	Target Neighborhood Hits	337	Shared Neighborhood Hits	109
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HCK_HUMAN
θ value	θ > 10 (rank : 1209)	NC score	0.066601 (rank : 841)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1035	Shared Neighborhood Hits	170
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 1210)	NC score	0.067190 (rank : 833)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1029	Shared Neighborhood Hits	167
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HRX_HUMAN
θ value	θ > 10 (rank : 1211)	NC score	0.069226 (rank : 810)
Query Neighborhood Hits	1041	Target Neighborhood Hits	825	Shared Neighborhood Hits	167
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IF2P_HUMAN
θ value	θ > 10 (rank : 1212)	NC score	0.050258 (rank : 1125)
Query Neighborhood Hits	1041	Target Neighborhood Hits	889	Shared Neighborhood Hits	92
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF35_MOUSE
θ value	θ > 10 (rank : 1213)	NC score	0.054773 (rank : 1032)
Query Neighborhood Hits	1041	Target Neighborhood Hits	210	Shared Neighborhood Hits	99
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF4G1_HUMAN
θ value	θ > 10 (rank : 1214)	NC score	0.053658 (rank : 1051)
Query Neighborhood Hits	1041	Target Neighborhood Hits	347	Shared Neighborhood Hits	133
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IRS2_HUMAN
θ value	θ > 10 (rank : 1215)	NC score	0.063201 (rank : 877)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

ITK_HUMAN
θ value	θ > 10 (rank : 1216)	NC score	0.056291 (rank : 1005)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1016	Shared Neighborhood Hits	143
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 1217)	NC score	0.054344 (rank : 1042)
Query Neighborhood Hits	1041	Target Neighborhood Hits	985	Shared Neighborhood Hits	133
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JAG1_HUMAN
θ value	θ > 10 (rank : 1218)	NC score	0.060841 (rank : 923)
Query Neighborhood Hits	1041	Target Neighborhood Hits	514	Shared Neighborhood Hits	28
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 1219)	NC score	0.060376 (rank : 931)
Query Neighborhood Hits	1041	Target Neighborhood Hits	518	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 1220)	NC score	0.061409 (rank : 911)
Query Neighborhood Hits	1041	Target Neighborhood Hits	491	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 1221)	NC score	0.062662 (rank : 891)
Query Neighborhood Hits	1041	Target Neighborhood Hits	504	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KI67_HUMAN
θ value	θ > 10 (rank : 1222)	NC score	0.063596 (rank : 871)
Query Neighborhood Hits	1041	Target Neighborhood Hits	581	Shared Neighborhood Hits	110
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KR104_HUMAN
θ value	θ > 10 (rank : 1223)	NC score	0.053314 (rank : 1054)
Query Neighborhood Hits	1041	Target Neighborhood Hits	313	Shared Neighborhood Hits	20
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LAD1_HUMAN
θ value	θ > 10 (rank : 1224)	NC score	0.054588 (rank : 1037)
Query Neighborhood Hits	1041	Target Neighborhood Hits	441	Shared Neighborhood Hits	91
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LASP1_HUMAN
θ value	θ > 10 (rank : 1225)	NC score	0.105455 (rank : 572)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	121
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 1226)	NC score	0.105127 (rank : 573)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	122
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LBC_HUMAN
θ value	θ > 10 (rank : 1227)	NC score	0.065327 (rank : 851)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LCE1A_HUMAN
θ value	θ > 10 (rank : 1228)	NC score	0.053937 (rank : 1048)
Query Neighborhood Hits	1041	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 1229)	NC score	0.070435 (rank : 798)
Query Neighborhood Hits	1041	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 1230)	NC score	0.070314 (rank : 799)
Query Neighborhood Hits	1041	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 1231)	NC score	0.067190 (rank : 834)
Query Neighborhood Hits	1041	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 1232)	NC score	0.066110 (rank : 845)
Query Neighborhood Hits	1041	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCP2_MOUSE
θ value	θ > 10 (rank : 1233)	NC score	0.068679 (rank : 817)
Query Neighborhood Hits	1041	Target Neighborhood Hits	177	Shared Neighborhood Hits	60
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LDB3_HUMAN
θ value	θ > 10 (rank : 1234)	NC score	0.099334 (rank : 600)
Query Neighborhood Hits	1041	Target Neighborhood Hits	497	Shared Neighborhood Hits	205
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 1235)	NC score	0.096850 (rank : 614)
Query Neighborhood Hits	1041	Target Neighborhood Hits	510	Shared Neighborhood Hits	220
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LMO7_HUMAN
θ value	θ > 10 (rank : 1236)	NC score	0.062950 (rank : 882)
Query Neighborhood Hits	1041	Target Neighborhood Hits	507	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LRRK1_HUMAN
θ value	θ > 10 (rank : 1237)	NC score	0.076992 (rank : 735)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1237	Shared Neighborhood Hits	159
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LRRK1_MOUSE
θ value	θ > 10 (rank : 1238)	NC score	0.095548 (rank : 619)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1267	Shared Neighborhood Hits	180
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LTBP2_MOUSE
θ value	θ > 10 (rank : 1239)	NC score	0.050811 (rank : 1113)
Query Neighborhood Hits	1041	Target Neighborhood Hits	617	Shared Neighborhood Hits	59
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP4_MOUSE
θ value	θ > 10 (rank : 1240)	NC score	0.057170 (rank : 988)
Query Neighborhood Hits	1041	Target Neighborhood Hits	607	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYN_HUMAN
θ value	θ > 10 (rank : 1241)	NC score	0.064913 (rank : 855)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1022	Shared Neighborhood Hits	161
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 1242)	NC score	0.064575 (rank : 857)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1023	Shared Neighborhood Hits	160
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MADCA_HUMAN
θ value	θ > 10 (rank : 1243)	NC score	0.068518 (rank : 820)
Query Neighborhood Hits	1041	Target Neighborhood Hits	221	Shared Neighborhood Hits	94
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP1B_HUMAN
θ value	θ > 10 (rank : 1244)	NC score	0.056548 (rank : 1001)
Query Neighborhood Hits	1041	Target Neighborhood Hits	903	Shared Neighborhood Hits	136
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
θ value	θ > 10 (rank : 1245)	NC score	0.057904 (rank : 976)
Query Neighborhood Hits	1041	Target Neighborhood Hits	977	Shared Neighborhood Hits	152
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAP4_HUMAN
θ value	θ > 10 (rank : 1246)	NC score	0.060980 (rank : 921)
Query Neighborhood Hits	1041	Target Neighborhood Hits	428	Shared Neighborhood Hits	112
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	θ > 10 (rank : 1247)	NC score	0.065411 (rank : 848)
Query Neighborhood Hits	1041	Target Neighborhood Hits	409	Shared Neighborhood Hits	106
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 1248)	NC score	0.091056 (rank : 644)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	80
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 1249)	NC score	0.090565 (rank : 648)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	83
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MATK_HUMAN
θ value	θ > 10 (rank : 1250)	NC score	0.051432 (rank : 1100)
Query Neighborhood Hits	1041	Target Neighborhood Hits	954	Shared Neighborhood Hits	109
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 1251)	NC score	0.051438 (rank : 1099)
Query Neighborhood Hits	1041	Target Neighborhood Hits	952	Shared Neighborhood Hits	114
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MBD6_HUMAN
θ value	θ > 10 (rank : 1252)	NC score	0.135465 (rank : 468)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	167
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MCF2L_MOUSE
θ value	θ > 10 (rank : 1253)	NC score	0.072958 (rank : 774)
Query Neighborhood Hits	1041	Target Neighborhood Hits	255	Shared Neighborhood Hits	57
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 1254)	NC score	0.072054 (rank : 782)
Query Neighborhood Hits	1041	Target Neighborhood Hits	166	Shared Neighborhood Hits	47
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MEGF9_HUMAN
θ value	θ > 10 (rank : 1255)	NC score	0.050430 (rank : 1123)
Query Neighborhood Hits	1041	Target Neighborhood Hits	557	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MILK1_MOUSE
θ value	θ > 10 (rank : 1256)	NC score	0.073356 (rank : 769)
Query Neighborhood Hits	1041	Target Neighborhood Hits	788	Shared Neighborhood Hits	218
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MISS_MOUSE
θ value	θ > 10 (rank : 1257)	NC score	0.057139 (rank : 992)
Query Neighborhood Hits	1041	Target Neighborhood Hits	444	Shared Neighborhood Hits	124
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLKL_HUMAN
θ value	θ > 10 (rank : 1258)	NC score	0.057222 (rank : 987)
Query Neighborhood Hits	1041	Target Neighborhood Hits	600	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 1259)	NC score	0.052317 (rank : 1078)
Query Neighborhood Hits	1041	Target Neighborhood Hits	707	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MMRN1_HUMAN
θ value	θ > 10 (rank : 1260)	NC score	0.055457 (rank : 1017)
Query Neighborhood Hits	1041	Target Neighborhood Hits	636	Shared Neighborhood Hits	59
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MN1_HUMAN
θ value	θ > 10 (rank : 1261)	NC score	0.057491 (rank : 984)
Query Neighborhood Hits	1041	Target Neighborhood Hits	196	Shared Neighborhood Hits	85
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

MNT_HUMAN
θ value	θ > 10 (rank : 1262)	NC score	0.062575 (rank : 892)
Query Neighborhood Hits	1041	Target Neighborhood Hits	496	Shared Neighborhood Hits	136
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 1263)	NC score	0.058368 (rank : 969)
Query Neighborhood Hits	1041	Target Neighborhood Hits	432	Shared Neighborhood Hits	122
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MPP2_HUMAN
θ value	θ > 10 (rank : 1264)	NC score	0.073556 (rank : 765)
Query Neighborhood Hits	1041	Target Neighborhood Hits	173	Shared Neighborhood Hits	125
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 1265)	NC score	0.074879 (rank : 755)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	129
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP5_HUMAN
θ value	θ > 10 (rank : 1266)	NC score	0.093241 (rank : 631)
Query Neighborhood Hits	1041	Target Neighborhood Hits	231	Shared Neighborhood Hits	143
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	θ > 10 (rank : 1267)	NC score	0.092460 (rank : 636)
Query Neighborhood Hits	1041	Target Neighborhood Hits	226	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP6_HUMAN
θ value	θ > 10 (rank : 1268)	NC score	0.081472 (rank : 705)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	θ > 10 (rank : 1269)	NC score	0.081883 (rank : 700)
Query Neighborhood Hits	1041	Target Neighborhood Hits	187	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MUC13_MOUSE
θ value	θ > 10 (rank : 1270)	NC score	0.097548 (rank : 611)
Query Neighborhood Hits	1041	Target Neighborhood Hits	447	Shared Neighborhood Hits	109
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 1271)	NC score	0.103381 (rank : 579)
Query Neighborhood Hits	1041	Target Neighborhood Hits	388	Shared Neighborhood Hits	96
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 1272)	NC score	0.102922 (rank : 581)
Query Neighborhood Hits	1041	Target Neighborhood Hits	906	Shared Neighborhood Hits	222
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	θ > 10 (rank : 1273)	NC score	0.153681 (rank : 421)
Query Neighborhood Hits	1041	Target Neighborhood Hits	538	Shared Neighborhood Hits	215
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUCDL_MOUSE
θ value	θ > 10 (rank : 1274)	NC score	0.054084 (rank : 1045)
Query Neighborhood Hits	1041	Target Neighborhood Hits	461	Shared Neighborhood Hits	119
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MY18B_HUMAN
θ value	θ > 10 (rank : 1275)	NC score	0.050033 (rank : 1132)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1299	Shared Neighborhood Hits	161
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

NCF4_HUMAN
θ value	θ > 10 (rank : 1276)	NC score	0.111440 (rank : 553)
Query Neighborhood Hits	1041	Target Neighborhood Hits	161	Shared Neighborhood Hits	91
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 1277)	NC score	0.117275 (rank : 531)
Query Neighborhood Hits	1041	Target Neighborhood Hits	177	Shared Neighborhood Hits	101
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCOR2_MOUSE
θ value	θ > 10 (rank : 1278)	NC score	0.065268 (rank : 852)
Query Neighborhood Hits	1041	Target Neighborhood Hits	790	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NEB1_HUMAN
θ value	θ > 10 (rank : 1279)	NC score	0.136330 (rank : 466)
Query Neighborhood Hits	1041	Target Neighborhood Hits	829	Shared Neighborhood Hits	174
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NELFA_MOUSE
θ value	θ > 10 (rank : 1280)	NC score	0.050047 (rank : 1131)
Query Neighborhood Hits	1041	Target Neighborhood Hits	195	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NEUM_MOUSE
θ value	θ > 10 (rank : 1281)	NC score	0.051118 (rank : 1105)
Query Neighborhood Hits	1041	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NFH_HUMAN
θ value	θ > 10 (rank : 1282)	NC score	0.054588 (rank : 1036)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1242	Shared Neighborhood Hits	184
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NIPBL_HUMAN
θ value	θ > 10 (rank : 1283)	NC score	0.050265 (rank : 1124)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1311	Shared Neighborhood Hits	178
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOLC1_HUMAN
θ value	θ > 10 (rank : 1284)	NC score	0.098567 (rank : 606)
Query Neighborhood Hits	1041	Target Neighborhood Hits	452	Shared Neighborhood Hits	118
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NOS1_MOUSE
θ value	θ > 10 (rank : 1285)	NC score	0.057026 (rank : 995)
Query Neighborhood Hits	1041	Target Neighborhood Hits	155	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NPHP1_MOUSE
θ value	θ > 10 (rank : 1286)	NC score	0.109322 (rank : 558)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NSD1_MOUSE
θ value	θ > 10 (rank : 1287)	NC score	0.054313 (rank : 1043)
Query Neighborhood Hits	1041	Target Neighborhood Hits	472	Shared Neighborhood Hits	95
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

P85B_HUMAN
θ value	θ > 10 (rank : 1288)	NC score	0.056704 (rank : 999)
Query Neighborhood Hits	1041	Target Neighborhood Hits	543	Shared Neighborhood Hits	100
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 1289)	NC score	0.054513 (rank : 1039)
Query Neighborhood Hits	1041	Target Neighborhood Hits	519	Shared Neighborhood Hits	91
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PACN2_HUMAN
θ value	θ > 10 (rank : 1290)	NC score	0.112849 (rank : 545)
Query Neighborhood Hits	1041	Target Neighborhood Hits	339	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	θ > 10 (rank : 1291)	NC score	0.111747 (rank : 547)
Query Neighborhood Hits	1041	Target Neighborhood Hits	382	Shared Neighborhood Hits	148
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	θ > 10 (rank : 1292)	NC score	0.101247 (rank : 594)
Query Neighborhood Hits	1041	Target Neighborhood Hits	385	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	θ > 10 (rank : 1293)	NC score	0.102302 (rank : 587)
Query Neighborhood Hits	1041	Target Neighborhood Hits	380	Shared Neighborhood Hits	138
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PAR6A_HUMAN
θ value	θ > 10 (rank : 1294)	NC score	0.081708 (rank : 703)
Query Neighborhood Hits	1041	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	θ > 10 (rank : 1295)	NC score	0.079577 (rank : 717)
Query Neighborhood Hits	1041	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6B_HUMAN
θ value	θ > 10 (rank : 1296)	NC score	0.081541 (rank : 704)
Query Neighborhood Hits	1041	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	θ > 10 (rank : 1297)	NC score	0.082540 (rank : 692)
Query Neighborhood Hits	1041	Target Neighborhood Hits	128	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_HUMAN
θ value	θ > 10 (rank : 1298)	NC score	0.086393 (rank : 663)
Query Neighborhood Hits	1041	Target Neighborhood Hits	159	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	θ > 10 (rank : 1299)	NC score	0.082054 (rank : 696)
Query Neighborhood Hits	1041	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PCQAP_HUMAN
θ value	θ > 10 (rank : 1300)	NC score	0.087225 (rank : 658)
Query Neighborhood Hits	1041	Target Neighborhood Hits	549	Shared Neighborhood Hits	153
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 1301)	NC score	0.063855 (rank : 865)
Query Neighborhood Hits	1041	Target Neighborhood Hits	506	Shared Neighborhood Hits	134
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDC6I_HUMAN
θ value	θ > 10 (rank : 1302)	NC score	0.057149 (rank : 991)
Query Neighborhood Hits	1041	Target Neighborhood Hits	278	Shared Neighborhood Hits	119
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDC6I_MOUSE
θ value	θ > 10 (rank : 1303)	NC score	0.061110 (rank : 918)
Query Neighborhood Hits	1041	Target Neighborhood Hits	275	Shared Neighborhood Hits	120
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDCD7_HUMAN
θ value	θ > 10 (rank : 1304)	NC score	0.054368 (rank : 1040)
Query Neighborhood Hits	1041	Target Neighborhood Hits	255	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PDLI1_HUMAN
θ value	θ > 10 (rank : 1305)	NC score	0.077416 (rank : 731)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	87
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 1306)	NC score	0.076306 (rank : 742)
Query Neighborhood Hits	1041	Target Neighborhood Hits	213	Shared Neighborhood Hits	85
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI3_HUMAN
θ value	θ > 10 (rank : 1307)	NC score	0.073409 (rank : 768)
Query Neighborhood Hits	1041	Target Neighborhood Hits	199	Shared Neighborhood Hits	92
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_MOUSE
θ value	θ > 10 (rank : 1308)	NC score	0.070945 (rank : 793)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	90
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_HUMAN
θ value	θ > 10 (rank : 1309)	NC score	0.077233 (rank : 733)
Query Neighborhood Hits	1041	Target Neighborhood Hits	245	Shared Neighborhood Hits	103
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	θ > 10 (rank : 1310)	NC score	0.078490 (rank : 725)
Query Neighborhood Hits	1041	Target Neighborhood Hits	233	Shared Neighborhood Hits	99
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDZ11_MOUSE
θ value	θ > 10 (rank : 1311)	NC score	0.169551 (rank : 385)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	110
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZK4_HUMAN
θ value	θ > 10 (rank : 1312)	NC score	0.081766 (rank : 702)
Query Neighborhood Hits	1041	Target Neighborhood Hits	165	Shared Neighborhood Hits	94
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	θ > 10 (rank : 1313)	NC score	0.081143 (rank : 707)
Query Neighborhood Hits	1041	Target Neighborhood Hits	165	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PELP1_HUMAN
θ value	θ > 10 (rank : 1314)	NC score	0.082006 (rank : 697)
Query Neighborhood Hits	1041	Target Neighborhood Hits	596	Shared Neighborhood Hits	152
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PEX13_HUMAN
θ value	θ > 10 (rank : 1315)	NC score	0.075124 (rank : 752)
Query Neighborhood Hits	1041	Target Neighborhood Hits	128	Shared Neighborhood Hits	82
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 1316)	NC score	0.072861 (rank : 775)
Query Neighborhood Hits	1041	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PI5PA_HUMAN
θ value	θ > 10 (rank : 1317)	NC score	0.083919 (rank : 679)
Query Neighborhood Hits	1041	Target Neighborhood Hits	749	Shared Neighborhood Hits	217
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PI5PA_MOUSE
θ value	θ > 10 (rank : 1318)	NC score	0.066967 (rank : 836)
Query Neighborhood Hits	1041	Target Neighborhood Hits	331	Shared Neighborhood Hits	141
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PICK1_HUMAN
θ value	θ > 10 (rank : 1319)	NC score	0.084174 (rank : 676)
Query Neighborhood Hits	1041	Target Neighborhood Hits	132	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	θ > 10 (rank : 1320)	NC score	0.083430 (rank : 682)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	88
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PININ_MOUSE
θ value	θ > 10 (rank : 1321)	NC score	0.057111 (rank : 993)
Query Neighborhood Hits	1041	Target Neighborhood Hits	777	Shared Neighborhood Hits	124
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PKHA6_MOUSE
θ value	θ > 10 (rank : 1322)	NC score	0.053647 (rank : 1052)
Query Neighborhood Hits	1041	Target Neighborhood Hits	591	Shared Neighborhood Hits	125
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHG1_HUMAN
θ value	θ > 10 (rank : 1323)	NC score	0.090337 (rank : 649)
Query Neighborhood Hits	1041	Target Neighborhood Hits	174	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PO121_HUMAN
θ value	θ > 10 (rank : 1324)	NC score	0.079276 (rank : 720)
Query Neighborhood Hits	1041	Target Neighborhood Hits	344	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 1325)	NC score	0.083063 (rank : 686)
Query Neighborhood Hits	1041	Target Neighborhood Hits	345	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PPIP1_HUMAN
θ value	θ > 10 (rank : 1326)	NC score	0.132872 (rank : 478)
Query Neighborhood Hits	1041	Target Neighborhood Hits	389	Shared Neighborhood Hits	143
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PPIP1_MOUSE
θ value	θ > 10 (rank : 1327)	NC score	0.135434 (rank : 469)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	147
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PPRB_MOUSE
θ value	θ > 10 (rank : 1328)	NC score	0.054792 (rank : 1030)
Query Neighborhood Hits	1041	Target Neighborhood Hits	354	Shared Neighborhood Hits	104
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRB3_HUMAN
θ value	θ > 10 (rank : 1329)	NC score	0.155246 (rank : 419)
Query Neighborhood Hits	1041	Target Neighborhood Hits	318	Shared Neighborhood Hits	161
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 1330)	NC score	0.161726 (rank : 412)
Query Neighborhood Hits	1041	Target Neighborhood Hits	330	Shared Neighborhood Hits	162
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 1331)	NC score	0.130956 (rank : 491)
Query Neighborhood Hits	1041	Target Neighborhood Hits	764	Shared Neighborhood Hits	226
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 1332)	NC score	0.106615 (rank : 568)
Query Neighborhood Hits	1041	Target Neighborhood Hits	624	Shared Neighborhood Hits	182
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 1333)	NC score	0.175986 (rank : 370)
Query Neighborhood Hits	1041	Target Neighborhood Hits	385	Shared Neighborhood Hits	186
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 1334)	NC score	0.172346 (rank : 378)
Query Neighborhood Hits	1041	Target Neighborhood Hits	347	Shared Neighborhood Hits	169
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 1335)	NC score	0.086166 (rank : 665)
Query Neighborhood Hits	1041	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 1336)	NC score	0.072721 (rank : 776)
Query Neighborhood Hits	1041	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 1337)	NC score	0.056253 (rank : 1006)
Query Neighborhood Hits	1041	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR12_HUMAN
θ value	θ > 10 (rank : 1338)	NC score	0.157400 (rank : 416)
Query Neighborhood Hits	1041	Target Neighborhood Hits	460	Shared Neighborhood Hits	212
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 1339)	NC score	0.078673 (rank : 723)
Query Neighborhood Hits	1041	Target Neighborhood Hits	105	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 1340)	NC score	0.061459 (rank : 908)
Query Neighborhood Hits	1041	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR8_HUMAN
θ value	θ > 10 (rank : 1341)	NC score	0.055796 (rank : 1012)
Query Neighborhood Hits	1041	Target Neighborhood Hits	217	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PS1C2_HUMAN
θ value	θ > 10 (rank : 1342)	NC score	0.052886 (rank : 1062)
Query Neighborhood Hits	1041	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PTK6_HUMAN
θ value	θ > 10 (rank : 1343)	NC score	0.061128 (rank : 915)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1020	Shared Neighborhood Hits	157
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 1344)	NC score	0.062675 (rank : 890)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1026	Shared Neighborhood Hits	161
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTN23_HUMAN
θ value	θ > 10 (rank : 1345)	NC score	0.055852 (rank : 1011)
Query Neighborhood Hits	1041	Target Neighborhood Hits	646	Shared Neighborhood Hits	197
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 1346)	NC score	0.050253 (rank : 1126)
Query Neighborhood Hits	1041	Target Neighborhood Hits	726	Shared Neighborhood Hits	210
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PZRN4_HUMAN
θ value	θ > 10 (rank : 1347)	NC score	0.123446 (rank : 519)
Query Neighborhood Hits	1041	Target Neighborhood Hits	438	Shared Neighborhood Hits	135
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RAPH1_HUMAN
θ value	θ > 10 (rank : 1348)	NC score	0.115924 (rank : 534)
Query Neighborhood Hits	1041	Target Neighborhood Hits	593	Shared Neighborhood Hits	222
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RASA1_HUMAN
θ value	θ > 10 (rank : 1349)	NC score	0.052386 (rank : 1076)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	67
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RBBP6_HUMAN
θ value	θ > 10 (rank : 1350)	NC score	0.052070 (rank : 1083)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1135	Shared Neighborhood Hits	148
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBM12_MOUSE
θ value	θ > 10 (rank : 1351)	NC score	0.051719 (rank : 1092)
Query Neighborhood Hits	1041	Target Neighborhood Hits	313	Shared Neighborhood Hits	110
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RERE_HUMAN
θ value	θ > 10 (rank : 1352)	NC score	0.110932 (rank : 555)
Query Neighborhood Hits	1041	Target Neighborhood Hits	779	Shared Neighborhood Hits	250
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 1353)	NC score	0.113638 (rank : 540)
Query Neighborhood Hits	1041	Target Neighborhood Hits	785	Shared Neighborhood Hits	251
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RGNEF_MOUSE
θ value	θ > 10 (rank : 1354)	NC score	0.074259 (rank : 761)
Query Neighborhood Hits	1041	Target Neighborhood Hits	641	Shared Neighborhood Hits	94
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RHG04_HUMAN
θ value	θ > 10 (rank : 1355)	NC score	0.071806 (rank : 786)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	125
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG26_HUMAN
θ value	θ > 10 (rank : 1356)	NC score	0.070975 (rank : 792)
Query Neighborhood Hits	1041	Target Neighborhood Hits	281	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RIN3_MOUSE
θ value	θ > 10 (rank : 1357)	NC score	0.056315 (rank : 1004)
Query Neighborhood Hits	1041	Target Neighborhood Hits	239	Shared Neighborhood Hits	99
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIPK2_HUMAN
θ value	θ > 10 (rank : 1358)	NC score	0.057434 (rank : 985)
Query Neighborhood Hits	1041	Target Neighborhood Hits	774	Shared Neighborhood Hits	68
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 1359)	NC score	0.052139 (rank : 1081)
Query Neighborhood Hits	1041	Target Neighborhood Hits	776	Shared Neighborhood Hits	66
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RPB1_HUMAN
θ value	θ > 10 (rank : 1360)	NC score	0.074636 (rank : 757)
Query Neighborhood Hits	1041	Target Neighborhood Hits	362	Shared Neighborhood Hits	133
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 1361)	NC score	0.075620 (rank : 748)
Query Neighborhood Hits	1041	Target Neighborhood Hits	363	Shared Neighborhood Hits	133
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RSNL2_HUMAN
θ value	θ > 10 (rank : 1362)	NC score	0.188711 (rank : 345)
Query Neighborhood Hits	1041	Target Neighborhood Hits	136	Shared Neighborhood Hits	111
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	θ > 10 (rank : 1363)	NC score	0.164714 (rank : 398)
Query Neighborhood Hits	1041	Target Neighborhood Hits	129	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RUSC1_HUMAN
θ value	θ > 10 (rank : 1364)	NC score	0.069039 (rank : 814)
Query Neighborhood Hits	1041	Target Neighborhood Hits	226	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC1_MOUSE
θ value	θ > 10 (rank : 1365)	NC score	0.059308 (rank : 953)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

S23IP_MOUSE
θ value	θ > 10 (rank : 1366)	NC score	0.060377 (rank : 930)
Query Neighborhood Hits	1041	Target Neighborhood Hits	363	Shared Neighborhood Hits	121
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SASH1_HUMAN
θ value	θ > 10 (rank : 1367)	NC score	0.069510 (rank : 807)
Query Neighborhood Hits	1041	Target Neighborhood Hits	292	Shared Neighborhood Hits	129
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SASH1_MOUSE
θ value	θ > 10 (rank : 1368)	NC score	0.069557 (rank : 806)
Query Neighborhood Hits	1041	Target Neighborhood Hits	263	Shared Neighborhood Hits	103
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SC24D_HUMAN
θ value	θ > 10 (rank : 1369)	NC score	0.053171 (rank : 1056)
Query Neighborhood Hits	1041	Target Neighborhood Hits	173	Shared Neighborhood Hits	79
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SELPL_MOUSE
θ value	θ > 10 (rank : 1370)	NC score	0.076433 (rank : 739)
Query Neighborhood Hits	1041	Target Neighborhood Hits	588	Shared Neighborhood Hits	151
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SELV_HUMAN
θ value	θ > 10 (rank : 1371)	NC score	0.073938 (rank : 762)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	68
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 1372)	NC score	0.113020 (rank : 543)
Query Neighborhood Hits	1041	Target Neighborhood Hits	690	Shared Neighborhood Hits	207
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETB1_MOUSE
θ value	θ > 10 (rank : 1373)	NC score	0.055285 (rank : 1022)
Query Neighborhood Hits	1041	Target Neighborhood Hits	150	Shared Neighborhood Hits	43
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETD2_HUMAN
θ value	θ > 10 (rank : 1374)	NC score	0.061232 (rank : 913)
Query Neighborhood Hits	1041	Target Neighborhood Hits	412	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SF01_HUMAN
θ value	θ > 10 (rank : 1375)	NC score	0.076404 (rank : 740)
Query Neighborhood Hits	1041	Target Neighborhood Hits	287	Shared Neighborhood Hits	133
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 1376)	NC score	0.062769 (rank : 889)
Query Neighborhood Hits	1041	Target Neighborhood Hits	240	Shared Neighborhood Hits	111
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_HUMAN
θ value	θ > 10 (rank : 1377)	NC score	0.102770 (rank : 583)
Query Neighborhood Hits	1041	Target Neighborhood Hits	263	Shared Neighborhood Hits	113
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 1378)	NC score	0.108661 (rank : 562)
Query Neighborhood Hits	1041	Target Neighborhood Hits	247	Shared Neighborhood Hits	114
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_MOUSE
θ value	θ > 10 (rank : 1379)	NC score	0.092370 (rank : 637)
Query Neighborhood Hits	1041	Target Neighborhood Hits	958	Shared Neighborhood Hits	247
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 1380)	NC score	0.067616 (rank : 832)
Query Neighborhood Hits	1041	Target Neighborhood Hits	368	Shared Neighborhood Hits	117
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGIP1_HUMAN
θ value	θ > 10 (rank : 1381)	NC score	0.068983 (rank : 815)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	θ > 10 (rank : 1382)	NC score	0.073058 (rank : 772)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SHB_MOUSE
θ value	θ > 10 (rank : 1383)	NC score	0.050620 (rank : 1115)
Query Neighborhood Hits	1041	Target Neighborhood Hits	137	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC1_HUMAN
θ value	θ > 10 (rank : 1384)	NC score	0.057657 (rank : 981)
Query Neighborhood Hits	1041	Target Neighborhood Hits	170	Shared Neighborhood Hits	59
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	θ > 10 (rank : 1385)	NC score	0.055368 (rank : 1019)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 1386)	NC score	0.050845 (rank : 1111)
Query Neighborhood Hits	1041	Target Neighborhood Hits	170	Shared Neighborhood Hits	51
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC3_HUMAN
θ value	θ > 10 (rank : 1387)	NC score	0.055721 (rank : 1015)
Query Neighborhood Hits	1041	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 1388)	NC score	0.056536 (rank : 1002)
Query Neighborhood Hits	1041	Target Neighborhood Hits	151	Shared Neighborhood Hits	48
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHD_HUMAN
θ value	θ > 10 (rank : 1389)	NC score	0.053833 (rank : 1049)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_HUMAN
θ value	θ > 10 (rank : 1390)	NC score	0.051415 (rank : 1101)
Query Neighborhood Hits	1041	Target Neighborhood Hits	164	Shared Neighborhood Hits	45
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SIPA1_MOUSE
θ value	θ > 10 (rank : 1391)	NC score	0.060047 (rank : 939)
Query Neighborhood Hits	1041	Target Neighborhood Hits	158	Shared Neighborhood Hits	36
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SLAP1_HUMAN
θ value	θ > 10 (rank : 1392)	NC score	0.059375 (rank : 951)
Query Neighborhood Hits	1041	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 1393)	NC score	0.058694 (rank : 963)
Query Neighborhood Hits	1041	Target Neighborhood Hits	117	Shared Neighborhood Hits	38
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_HUMAN
θ value	θ > 10 (rank : 1394)	NC score	0.063179 (rank : 879)
Query Neighborhood Hits	1041	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 1395)	NC score	0.063455 (rank : 873)
Query Neighborhood Hits	1041	Target Neighborhood Hits	136	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SLY_MOUSE
θ value	θ > 10 (rank : 1396)	NC score	0.065383 (rank : 849)
Query Neighborhood Hits	1041	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SMAP1_HUMAN
θ value	θ > 10 (rank : 1397)	NC score	0.058650 (rank : 964)
Query Neighborhood Hits	1041	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 1398)	NC score	0.059616 (rank : 949)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 1399)	NC score	0.055981 (rank : 1009)
Query Neighborhood Hits	1041	Target Neighborhood Hits	74	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 1400)	NC score	0.055672 (rank : 1016)
Query Neighborhood Hits	1041	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMR1_MOUSE
θ value	θ > 10 (rank : 1401)	NC score	0.061122 (rank : 917)
Query Neighborhood Hits	1041	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 1402)	NC score	0.082758 (rank : 687)
Query Neighborhood Hits	1041	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SNTB1_HUMAN
θ value	θ > 10 (rank : 1403)	NC score	0.121974 (rank : 523)
Query Neighborhood Hits	1041	Target Neighborhood Hits	157	Shared Neighborhood Hits	113
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	θ > 10 (rank : 1404)	NC score	0.121750 (rank : 524)
Query Neighborhood Hits	1041	Target Neighborhood Hits	160	Shared Neighborhood Hits	112
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNX18_HUMAN
θ value	θ > 10 (rank : 1405)	NC score	0.062118 (rank : 898)
Query Neighborhood Hits	1041	Target Neighborhood Hits	207	Shared Neighborhood Hits	100
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	θ > 10 (rank : 1406)	NC score	0.063799 (rank : 866)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	96
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX9_HUMAN
θ value	θ > 10 (rank : 1407)	NC score	0.050618 (rank : 1116)
Query Neighborhood Hits	1041	Target Neighborhood Hits	148	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SOS1_HUMAN
θ value	θ > 10 (rank : 1408)	NC score	0.050170 (rank : 1128)
Query Neighborhood Hits	1041	Target Neighborhood Hits	274	Shared Neighborhood Hits	83
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	θ > 10 (rank : 1409)	NC score	0.052847 (rank : 1063)
Query Neighborhood Hits	1041	Target Neighborhood Hits	281	Shared Neighborhood Hits	84
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SPN90_HUMAN
θ value	θ > 10 (rank : 1410)	NC score	0.060540 (rank : 927)
Query Neighborhood Hits	1041	Target Neighborhood Hits	157	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPN90_MOUSE
θ value	θ > 10 (rank : 1411)	NC score	0.053969 (rank : 1047)
Query Neighborhood Hits	1041	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPTA1_HUMAN
θ value	θ > 10 (rank : 1412)	NC score	0.057831 (rank : 978)
Query Neighborhood Hits	1041	Target Neighborhood Hits	748	Shared Neighborhood Hits	151
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 1413)	NC score	0.058214 (rank : 972)
Query Neighborhood Hits	1041	Target Neighborhood Hits	675	Shared Neighborhood Hits	140
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SREC2_HUMAN
θ value	θ > 10 (rank : 1414)	NC score	0.066742 (rank : 838)
Query Neighborhood Hits	1041	Target Neighborhood Hits	645	Shared Neighborhood Hits	122
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 1415)	NC score	0.059692 (rank : 946)
Query Neighborhood Hits	1041	Target Neighborhood Hits	605	Shared Neighborhood Hits	93
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SRGP1_HUMAN
θ value	θ > 10 (rank : 1416)	NC score	0.060886 (rank : 922)
Query Neighborhood Hits	1041	Target Neighborhood Hits	390	Shared Neighborhood Hits	127
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 1417)	NC score	0.060442 (rank : 928)
Query Neighborhood Hits	1041	Target Neighborhood Hits	331	Shared Neighborhood Hits	123
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 1418)	NC score	0.061310 (rank : 912)
Query Neighborhood Hits	1041	Target Neighborhood Hits	324	Shared Neighborhood Hits	124
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRMS_MOUSE
θ value	θ > 10 (rank : 1419)	NC score	0.050986 (rank : 1108)
Query Neighborhood Hits	1041	Target Neighborhood Hits	964	Shared Neighborhood Hits	115
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SRRM1_HUMAN
θ value	θ > 10 (rank : 1420)	NC score	0.137035 (rank : 463)
Query Neighborhood Hits	1041	Target Neighborhood Hits	690	Shared Neighborhood Hits	203
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

STXB4_HUMAN
θ value	θ > 10 (rank : 1421)	NC score	0.084375 (rank : 674)
Query Neighborhood Hits	1041	Target Neighborhood Hits	616	Shared Neighborhood Hits	112
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 1422)	NC score	0.082748 (rank : 688)
Query Neighborhood Hits	1041	Target Neighborhood Hits	629	Shared Neighborhood Hits	115
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYJ2B_HUMAN
θ value	θ > 10 (rank : 1423)	NC score	0.166279 (rank : 391)
Query Neighborhood Hits	1041	Target Neighborhood Hits	162	Shared Neighborhood Hits	111
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

SYN1_HUMAN
θ value	θ > 10 (rank : 1424)	NC score	0.092948 (rank : 633)
Query Neighborhood Hits	1041	Target Neighborhood Hits	419	Shared Neighborhood Hits	194
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 1425)	NC score	0.083081 (rank : 685)
Query Neighborhood Hits	1041	Target Neighborhood Hits	363	Shared Neighborhood Hits	171
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ1_HUMAN
θ value	θ > 10 (rank : 1426)	NC score	0.076464 (rank : 738)
Query Neighborhood Hits	1041	Target Neighborhood Hits	498	Shared Neighborhood Hits	182
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNP2_HUMAN
θ value	θ > 10 (rank : 1427)	NC score	0.099784 (rank : 599)
Query Neighborhood Hits	1041	Target Neighborhood Hits	323	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYNP2_MOUSE
θ value	θ > 10 (rank : 1428)	NC score	0.111503 (rank : 552)
Query Neighborhood Hits	1041	Target Neighborhood Hits	252	Shared Neighborhood Hits	141
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

T22D2_HUMAN
θ value	θ > 10 (rank : 1429)	NC score	0.090091 (rank : 650)
Query Neighborhood Hits	1041	Target Neighborhood Hits	250	Shared Neighborhood Hits	111
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TACC2_HUMAN
θ value	θ > 10 (rank : 1430)	NC score	0.055362 (rank : 1020)
Query Neighborhood Hits	1041	Target Neighborhood Hits	856	Shared Neighborhood Hits	139
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 1431)	NC score	0.059559 (rank : 950)
Query Neighborhood Hits	1041	Target Neighborhood Hits	774	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TAF4_HUMAN
θ value	θ > 10 (rank : 1432)	NC score	0.143702 (rank : 447)
Query Neighborhood Hits	1041	Target Neighborhood Hits	687	Shared Neighborhood Hits	216
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_MOUSE
θ value	θ > 10 (rank : 1433)	NC score	0.075440 (rank : 749)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1133	Shared Neighborhood Hits	194
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_HUMAN
θ value	θ > 10 (rank : 1434)	NC score	0.062833 (rank : 884)
Query Neighborhood Hits	1041	Target Neighborhood Hits	448	Shared Neighborhood Hits	132
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TAU_MOUSE
θ value	θ > 10 (rank : 1435)	NC score	0.063254 (rank : 876)
Query Neighborhood Hits	1041	Target Neighborhood Hits	502	Shared Neighborhood Hits	137
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TB182_HUMAN
θ value	θ > 10 (rank : 1436)	NC score	0.060797 (rank : 925)
Query Neighborhood Hits	1041	Target Neighborhood Hits	414	Shared Neighborhood Hits	117
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCOF_HUMAN
θ value	θ > 10 (rank : 1437)	NC score	0.093405 (rank : 628)
Query Neighborhood Hits	1041	Target Neighborhood Hits	543	Shared Neighborhood Hits	135
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 1438)	NC score	0.102322 (rank : 586)
Query Neighborhood Hits	1041	Target Neighborhood Hits	471	Shared Neighborhood Hits	137
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 1439)	NC score	0.063069 (rank : 880)
Query Neighborhood Hits	1041	Target Neighborhood Hits	929	Shared Neighborhood Hits	157
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 1440)	NC score	0.065526 (rank : 847)
Query Neighborhood Hits	1041	Target Neighborhood Hits	947	Shared Neighborhood Hits	165
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEC_MOUSE
θ value	θ > 10 (rank : 1441)	NC score	0.059097 (rank : 958)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1006	Shared Neighborhood Hits	150
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TM108_HUMAN
θ value	θ > 10 (rank : 1442)	NC score	0.058062 (rank : 974)
Query Neighborhood Hits	1041	Target Neighborhood Hits	166	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TM108_MOUSE
θ value	θ > 10 (rank : 1443)	NC score	0.064957 (rank : 854)
Query Neighborhood Hits	1041	Target Neighborhood Hits	336	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 1444)	NC score	0.063756 (rank : 867)
Query Neighborhood Hits	1041	Target Neighborhood Hits	140	Shared Neighborhood Hits	69
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TP53B_MOUSE
θ value	θ > 10 (rank : 1445)	NC score	0.050923 (rank : 1109)
Query Neighborhood Hits	1041	Target Neighborhood Hits	644	Shared Neighborhood Hits	134
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRDN_HUMAN
θ value	θ > 10 (rank : 1446)	NC score	0.061812 (rank : 901)
Query Neighborhood Hits	1041	Target Neighborhood Hits	542	Shared Neighborhood Hits	65
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TROAP_HUMAN
θ value	θ > 10 (rank : 1447)	NC score	0.054725 (rank : 1033)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	92
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TRPC3_HUMAN
θ value	θ > 10 (rank : 1448)	NC score	0.060249 (rank : 936)
Query Neighborhood Hits	1041	Target Neighborhood Hits	137	Shared Neighborhood Hits	72
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC3_MOUSE
θ value	θ > 10 (rank : 1449)	NC score	0.054694 (rank : 1034)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_HUMAN
θ value	θ > 10 (rank : 1450)	NC score	0.077043 (rank : 734)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC6_MOUSE
θ value	θ > 10 (rank : 1451)	NC score	0.054360 (rank : 1041)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	84
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPV1_HUMAN
θ value	θ > 10 (rank : 1452)	NC score	0.181694 (rank : 355)
Query Neighborhood Hits	1041	Target Neighborhood Hits	184	Shared Neighborhood Hits	137
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
θ value	θ > 10 (rank : 1453)	NC score	0.192734 (rank : 340)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	143
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV2_HUMAN
θ value	θ > 10 (rank : 1454)	NC score	0.172981 (rank : 376)
Query Neighborhood Hits	1041	Target Neighborhood Hits	130	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 1455)	NC score	0.129167 (rank : 500)
Query Neighborhood Hits	1041	Target Neighborhood Hits	111	Shared Neighborhood Hits	84
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV3_HUMAN
θ value	θ > 10 (rank : 1456)	NC score	0.193523 (rank : 339)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	132
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
θ value	θ > 10 (rank : 1457)	NC score	0.195624 (rank : 333)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	θ > 10 (rank : 1458)	NC score	0.102562 (rank : 585)
Query Neighborhood Hits	1041	Target Neighborhood Hits	150	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 1459)	NC score	0.090653 (rank : 647)
Query Neighborhood Hits	1041	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TXK_HUMAN
θ value	θ > 10 (rank : 1460)	NC score	0.061422 (rank : 910)
Query Neighborhood Hits	1041	Target Neighborhood Hits	971	Shared Neighborhood Hits	135
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1461)	NC score	0.061195 (rank : 914)
Query Neighborhood Hits	1041	Target Neighborhood Hits	980	Shared Neighborhood Hits	145
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

VASP_HUMAN
θ value	θ > 10 (rank : 1462)	NC score	0.050616 (rank : 1117)
Query Neighborhood Hits	1041	Target Neighborhood Hits	201	Shared Neighborhood Hits	101
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VCX1_HUMAN
θ value	θ > 10 (rank : 1463)	NC score	0.053615 (rank : 1053)
Query Neighborhood Hits	1041	Target Neighborhood Hits	129	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 1464)	NC score	0.058380 (rank : 967)
Query Neighborhood Hits	1041	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 1465)	NC score	0.056895 (rank : 997)
Query Neighborhood Hits	1041	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

WASF1_HUMAN
θ value	θ > 10 (rank : 1466)	NC score	0.070255 (rank : 800)
Query Neighborhood Hits	1041	Target Neighborhood Hits	260	Shared Neighborhood Hits	137
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 1467)	NC score	0.072151 (rank : 780)
Query Neighborhood Hits	1041	Target Neighborhood Hits	261	Shared Neighborhood Hits	133
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_HUMAN
θ value	θ > 10 (rank : 1468)	NC score	0.074583 (rank : 758)
Query Neighborhood Hits	1041	Target Neighborhood Hits	280	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 1469)	NC score	0.084967 (rank : 671)
Query Neighborhood Hits	1041	Target Neighborhood Hits	315	Shared Neighborhood Hits	163
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_HUMAN
θ value	θ > 10 (rank : 1470)	NC score	0.057538 (rank : 982)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASF3_MOUSE
θ value	θ > 10 (rank : 1471)	NC score	0.054779 (rank : 1031)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WASF4_HUMAN
θ value	θ > 10 (rank : 1472)	NC score	0.071827 (rank : 785)
Query Neighborhood Hits	1041	Target Neighborhood Hits	282	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASL_HUMAN
θ value	θ > 10 (rank : 1473)	NC score	0.091502 (rank : 643)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	163
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 1474)	NC score	0.093389 (rank : 629)
Query Neighborhood Hits	1041	Target Neighborhood Hits	339	Shared Neighborhood Hits	174
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 1475)	NC score	0.061618 (rank : 905)
Query Neighborhood Hits	1041	Target Neighborhood Hits	195	Shared Neighborhood Hits	109
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 1476)	NC score	0.068276 (rank : 825)
Query Neighborhood Hits	1041	Target Neighborhood Hits	223	Shared Neighborhood Hits	115
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 1477)	NC score	0.102038 (rank : 589)
Query Neighborhood Hits	1041	Target Neighborhood Hits	354	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 1478)	NC score	0.101400 (rank : 593)
Query Neighborhood Hits	1041	Target Neighborhood Hits	362	Shared Neighborhood Hits	146
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 1479)	NC score	0.058505 (rank : 966)
Query Neighborhood Hits	1041	Target Neighborhood Hits	273	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WNK4_HUMAN
θ value	θ > 10 (rank : 1480)	NC score	0.052378 (rank : 1077)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1043	Shared Neighborhood Hits	189
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

YLPM1_HUMAN
θ value	θ > 10 (rank : 1481)	NC score	0.090750 (rank : 645)
Query Neighborhood Hits	1041	Target Neighborhood Hits	670	Shared Neighborhood Hits	198
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 1482)	NC score	0.106972 (rank : 566)
Query Neighborhood Hits	1041	Target Neighborhood Hits	505	Shared Neighborhood Hits	187
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZAN_MOUSE
θ value	θ > 10 (rank : 1483)	NC score	0.064356 (rank : 859)
Query Neighborhood Hits	1041	Target Neighborhood Hits	808	Shared Neighborhood Hits	82
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZC313_HUMAN
θ value	θ > 10 (rank : 1484)	NC score	0.050536 (rank : 1119)
Query Neighborhood Hits	1041	Target Neighborhood Hits	772	Shared Neighborhood Hits	104
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZN598_HUMAN
θ value	θ > 10 (rank : 1485)	NC score	0.051494 (rank : 1096)
Query Neighborhood Hits	1041	Target Neighborhood Hits	339	Shared Neighborhood Hits	92
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZO1_HUMAN
θ value	θ > 10 (rank : 1486)	NC score	0.122560 (rank : 522)
Query Neighborhood Hits	1041	Target Neighborhood Hits	474	Shared Neighborhood Hits	202
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

Hits sorted by NC score

SHAN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1041	Shared Neighborhood Hits	1041
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANKR6_HUMAN
NC score	0.768151 (rank : 2)	θ value	4.29542e-18 (rank : 13)
Query Neighborhood Hits	1041	Target Neighborhood Hits	439	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

PSD10_HUMAN
NC score	0.764281 (rank : 3)	θ value	2.0648e-12 (rank : 48)
Query Neighborhood Hits	1041	Target Neighborhood Hits	301	Shared Neighborhood Hits	273
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.763207 (rank : 4)	θ value	1.2105e-12 (rank : 45)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	271
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR29_HUMAN
NC score	0.760977 (rank : 5)	θ value	6.00763e-12 (rank : 55)
Query Neighborhood Hits	1041	Target Neighborhood Hits	294	Shared Neighborhood Hits	267
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR50_HUMAN
NC score	0.758285 (rank : 6)	θ value	2.5182e-18 (rank : 12)
Query Neighborhood Hits	1041	Target Neighborhood Hits	361	Shared Neighborhood Hits	278
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR23_HUMAN
NC score	0.755796 (rank : 7)	θ value	1.42992e-13 (rank : 36)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	271
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR44_HUMAN
NC score	0.755271 (rank : 8)	θ value	5.25075e-16 (rank : 22)
Query Neighborhood Hits	1041	Target Neighborhood Hits	318	Shared Neighborhood Hits	272
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR23_MOUSE
NC score	0.754233 (rank : 9)	θ value	1.42992e-13 (rank : 37)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	269
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB10_HUMAN
NC score	0.754167 (rank : 10)	θ value	3.76295e-14 (rank : 30)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_MOUSE
NC score	0.754118 (rank : 11)	θ value	9.26847e-13 (rank : 43)
Query Neighborhood Hits	1041	Target Neighborhood Hits	301	Shared Neighborhood Hits	273
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANR28_MOUSE
NC score	0.754082 (rank : 12)	θ value	2.97466e-19 (rank : 7)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	273
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

TNKS1_HUMAN
NC score	0.753321 (rank : 13)	θ value	2.88119e-14 (rank : 29)
Query Neighborhood Hits	1041	Target Neighborhood Hits	477	Shared Neighborhood Hits	334
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR28_HUMAN
NC score	0.753118 (rank : 14)	θ value	3.88503e-19 (rank : 9)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	273
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANKR2_HUMAN
NC score	0.752751 (rank : 15)	θ value	1.16975e-15 (rank : 24)
Query Neighborhood Hits	1041	Target Neighborhood Hits	321	Shared Neighborhood Hits	272
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANKR1_HUMAN
NC score	0.752077 (rank : 16)	θ value	3.18553e-13 (rank : 41)
Query Neighborhood Hits	1041	Target Neighborhood Hits	308	Shared Neighborhood Hits	268
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR2_MOUSE
NC score	0.751993 (rank : 17)	θ value	1.29331e-14 (rank : 28)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	273
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR1_MOUSE
NC score	0.751089 (rank : 18)	θ value	4.16044e-13 (rank : 42)
Query Neighborhood Hits	1041	Target Neighborhood Hits	316	Shared Neighborhood Hits	271
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB8_MOUSE
NC score	0.751031 (rank : 19)	θ value	4.30538e-10 (rank : 78)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	270
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_HUMAN
NC score	0.750612 (rank : 20)	θ value	9.59137e-10 (rank : 83)
Query Neighborhood Hits	1041	Target Neighborhood Hits	294	Shared Neighborhood Hits	270
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB3_HUMAN
NC score	0.748567 (rank : 21)	θ value	1.02475e-11 (rank : 60)
Query Neighborhood Hits	1041	Target Neighborhood Hits	316	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

FANK1_HUMAN
NC score	0.748339 (rank : 22)	θ value	4.59992e-12 (rank : 54)
Query Neighborhood Hits	1041	Target Neighborhood Hits	326	Shared Neighborhood Hits	270
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANR52_MOUSE
NC score	0.748221 (rank : 23)	θ value	1.80466e-16 (rank : 19)
Query Neighborhood Hits	1041	Target Neighborhood Hits	318	Shared Neighborhood Hits	273
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ASB3_MOUSE
NC score	0.748127 (rank : 24)	θ value	6.00763e-12 (rank : 56)
Query Neighborhood Hits	1041	Target Neighborhood Hits	316	Shared Neighborhood Hits	271
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR52_HUMAN
NC score	0.748115 (rank : 25)	θ value	4.74913e-17 (rank : 16)
Query Neighborhood Hits	1041	Target Neighborhood Hits	322	Shared Neighborhood Hits	273
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ASB7_MOUSE
NC score	0.748079 (rank : 26)	θ value	5.08577e-11 (rank : 69)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	268
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.748047 (rank : 27)	θ value	5.08577e-11 (rank : 68)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	268
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR16_HUMAN
NC score	0.747492 (rank : 28)	θ value	1.99992e-07 (rank : 122)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	267
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

FANK1_MOUSE
NC score	0.746276 (rank : 29)	θ value	3.89403e-11 (rank : 64)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	269
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

CSKI2_HUMAN
NC score	0.745246 (rank : 30)	θ value	4.59992e-12 (rank : 53)
Query Neighborhood Hits	1041	Target Neighborhood Hits	747	Shared Neighborhood Hits	486
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANK1_HUMAN
NC score	0.745206 (rank : 31)	θ value	7.32683e-18 (rank : 14)
Query Neighborhood Hits	1041	Target Neighborhood Hits	416	Shared Neighborhood Hits	285
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.745128 (rank : 32)	θ value	1.13037e-18 (rank : 11)
Query Neighborhood Hits	1041	Target Neighborhood Hits	430	Shared Neighborhood Hits	284
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ASB16_MOUSE
NC score	0.743802 (rank : 33)	θ value	1.09485e-13 (rank : 31)
Query Neighborhood Hits	1041	Target Neighborhood Hits	306	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANR42_MOUSE
NC score	0.743443 (rank : 34)	θ value	4.59992e-12 (rank : 51)
Query Neighborhood Hits	1041	Target Neighborhood Hits	334	Shared Neighborhood Hits	273
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

INVS_HUMAN
NC score	0.742661 (rank : 35)	θ value	1.47974e-10 (rank : 71)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	301
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB13_MOUSE
NC score	0.742154 (rank : 36)	θ value	2.52405e-10 (rank : 74)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANK3_HUMAN
NC score	0.741672 (rank : 37)	θ value	1.2077e-20 (rank : 6)
Query Neighborhood Hits	1041	Target Neighborhood Hits	853	Shared Neighborhood Hits	343
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

INVS_MOUSE
NC score	0.741452 (rank : 38)	θ value	2.52405e-10 (rank : 75)
Query Neighborhood Hits	1041	Target Neighborhood Hits	609	Shared Neighborhood Hits	331
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB16_HUMAN
NC score	0.740868 (rank : 39)	θ value	1.86753e-13 (rank : 38)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	265
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB13_HUMAN
NC score	0.740702 (rank : 40)	θ value	1.25267e-09 (rank : 85)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	267
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

CSKI2_MOUSE
NC score	0.740120 (rank : 41)	θ value	6.00763e-12 (rank : 57)
Query Neighborhood Hits	1041	Target Neighborhood Hits	812	Shared Neighborhood Hits	471
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TNKS2_HUMAN
NC score	0.739901 (rank : 42)	θ value	1.58096e-12 (rank : 47)
Query Neighborhood Hits	1041	Target Neighborhood Hits	361	Shared Neighborhood Hits	280
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ASB2_HUMAN
NC score	0.739351 (rank : 43)	θ value	1.9326e-10 (rank : 72)
Query Neighborhood Hits	1041	Target Neighborhood Hits	309	Shared Neighborhood Hits	272
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CSKI1_HUMAN
NC score	0.739106 (rank : 44)	θ value	3.64472e-09 (rank : 95)
Query Neighborhood Hits	1041	Target Neighborhood Hits	997	Shared Neighborhood Hits	505
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ASB2_MOUSE
NC score	0.735484 (rank : 45)	θ value	1.25267e-09 (rank : 86)
Query Neighborhood Hits	1041	Target Neighborhood Hits	321	Shared Neighborhood Hits	271
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

BCL3_HUMAN
NC score	0.734534 (rank : 46)	θ value	6.21693e-09 (rank : 101)
Query Neighborhood Hits	1041	Target Neighborhood Hits	324	Shared Neighborhood Hits	281
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

CSKI1_MOUSE
NC score	0.734368 (rank : 47)	θ value	3.64472e-09 (rank : 96)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1031	Shared Neighborhood Hits	515
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR42_HUMAN
NC score	0.734301 (rank : 48)	θ value	1.17247e-07 (rank : 118)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	265
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

PA2G6_MOUSE
NC score	0.733463 (rank : 49)	θ value	7.34386e-10 (rank : 82)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	269
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

BCL3_MOUSE
NC score	0.733276 (rank : 50)	θ value	3.29651e-10 (rank : 76)
Query Neighborhood Hits	1041	Target Neighborhood Hits	388	Shared Neighborhood Hits	291
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

PA2G6_HUMAN
NC score	0.730820 (rank : 51)	θ value	5.62301e-10 (rank : 81)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	266
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

GABP2_MOUSE
NC score	0.728265 (rank : 52)	θ value	4.0297e-08 (rank : 111)
Query Neighborhood Hits	1041	Target Neighborhood Hits	429	Shared Neighborhood Hits	277
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR39_HUMAN
NC score	0.727109 (rank : 53)	θ value	1.69304e-06 (rank : 150)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	270
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

GABP2_HUMAN
NC score	0.726309 (rank : 54)	θ value	3.08544e-08 (rank : 110)
Query Neighborhood Hits	1041	Target Neighborhood Hits	454	Shared Neighborhood Hits	278
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ASZ1_MOUSE
NC score	0.725605 (rank : 55)	θ value	4.59992e-12 (rank : 52)
Query Neighborhood Hits	1041	Target Neighborhood Hits	319	Shared Neighborhood Hits	264
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKS1_HUMAN
NC score	0.725103 (rank : 56)	θ value	1.58096e-12 (rank : 46)
Query Neighborhood Hits	1041	Target Neighborhood Hits	438	Shared Neighborhood Hits	315
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANR39_MOUSE
NC score	0.723443 (rank : 57)	θ value	4.92598e-06 (rank : 167)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	269
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANK2_HUMAN
NC score	0.723274 (rank : 58)	θ value	3.88503e-19 (rank : 8)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1615	Shared Neighborhood Hits	498
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASZ1_HUMAN
NC score	0.722696 (rank : 59)	θ value	5.62301e-10 (rank : 79)
Query Neighborhood Hits	1041	Target Neighborhood Hits	341	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB4_HUMAN
NC score	0.721924 (rank : 60)	θ value	1.63604e-09 (rank : 88)
Query Neighborhood Hits	1041	Target Neighborhood Hits	264	Shared Neighborhood Hits	256
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_MOUSE
NC score	0.721789 (rank : 61)	θ value	3.64472e-09 (rank : 94)
Query Neighborhood Hits	1041	Target Neighborhood Hits	265	Shared Neighborhood Hits	256
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

TRPA1_MOUSE
NC score	0.721236 (rank : 62)	θ value	1.80886e-08 (rank : 108)
Query Neighborhood Hits	1041	Target Neighborhood Hits	343	Shared Neighborhood Hits	271
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPA1_HUMAN
NC score	0.720693 (rank : 63)	θ value	8.11959e-09 (rank : 105)
Query Neighborhood Hits	1041	Target Neighborhood Hits	339	Shared Neighborhood Hits	269
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANKS6_MOUSE
NC score	0.720099 (rank : 64)	θ value	1.17247e-07 (rank : 117)
Query Neighborhood Hits	1041	Target Neighborhood Hits	435	Shared Neighborhood Hits	320
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

GABP3_MOUSE
NC score	0.718507 (rank : 65)	θ value	0.00134147 (rank : 295)
Query Neighborhood Hits	1041	Target Neighborhood Hits	330	Shared Neighborhood Hits	267
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANKS3_MOUSE
NC score	0.718288 (rank : 66)	θ value	4.76016e-09 (rank : 98)
Query Neighborhood Hits	1041	Target Neighborhood Hits	355	Shared Neighborhood Hits	268
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB15_HUMAN
NC score	0.718190 (rank : 67)	θ value	1.74796e-11 (rank : 63)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	266
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB11_MOUSE
NC score	0.718052 (rank : 68)	θ value	5.08577e-11 (rank : 66)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	250
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANR49_MOUSE
NC score	0.717963 (rank : 69)	θ value	0.00020696 (rank : 236)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	260
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR49_HUMAN
NC score	0.717690 (rank : 70)	θ value	2.44474e-05 (rank : 197)
Query Neighborhood Hits	1041	Target Neighborhood Hits	282	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASB11_HUMAN
NC score	0.717629 (rank : 71)	θ value	5.08577e-11 (rank : 65)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANKS6_HUMAN
NC score	0.716259 (rank : 72)	θ value	1.87187e-05 (rank : 191)
Query Neighborhood Hits	1041	Target Neighborhood Hits	411	Shared Neighborhood Hits	310
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ASB5_HUMAN
NC score	0.715303 (rank : 73)	θ value	7.84624e-12 (rank : 58)
Query Neighborhood Hits	1041	Target Neighborhood Hits	283	Shared Neighborhood Hits	262
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANKR7_HUMAN
NC score	0.714748 (rank : 74)	θ value	8.40245e-06 (rank : 177)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	265
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ASB9_HUMAN
NC score	0.714468 (rank : 75)	θ value	3.08544e-08 (rank : 109)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	248
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB5_MOUSE
NC score	0.711452 (rank : 76)	θ value	1.9326e-10 (rank : 73)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	251
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB15_MOUSE
NC score	0.711092 (rank : 77)	θ value	5.08577e-11 (rank : 67)
Query Neighborhood Hits	1041	Target Neighborhood Hits	292	Shared Neighborhood Hits	261
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

CT086_HUMAN
NC score	0.711091 (rank : 78)	θ value	9.29e-05 (rank : 221)
Query Neighborhood Hits	1041	Target Neighborhood Hits	277	Shared Neighborhood Hits	263
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANKS1_MOUSE
NC score	0.710879 (rank : 79)	θ value	6.21693e-09 (rank : 100)
Query Neighborhood Hits	1041	Target Neighborhood Hits	453	Shared Neighborhood Hits	319
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

MYPT1_MOUSE
NC score	0.710753 (rank : 80)	θ value	2.13673e-09 (rank : 91)
Query Neighborhood Hits	1041	Target Neighborhood Hits	539	Shared Neighborhood Hits	300
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MIB1_HUMAN
NC score	0.710580 (rank : 81)	θ value	1.09485e-13 (rank : 33)
Query Neighborhood Hits	1041	Target Neighborhood Hits	470	Shared Neighborhood Hits	280
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

ANKS3_HUMAN
NC score	0.710350 (rank : 82)	θ value	0.000461057 (rank : 262)
Query Neighborhood Hits	1041	Target Neighborhood Hits	355	Shared Neighborhood Hits	274
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

MIB1_MOUSE
NC score	0.709802 (rank : 83)	θ value	1.09485e-13 (rank : 34)
Query Neighborhood Hits	1041	Target Neighborhood Hits	471	Shared Neighborhood Hits	280
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

IKBA_HUMAN
NC score	0.707094 (rank : 84)	θ value	1.29631e-06 (rank : 148)
Query Neighborhood Hits	1041	Target Neighborhood Hits	280	Shared Neighborhood Hits	265
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

MTPN_MOUSE
NC score	0.706997 (rank : 85)	θ value	0.00134147 (rank : 299)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	255
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

MTPN_HUMAN
NC score	0.705673 (rank : 86)	θ value	0.000270298 (rank : 244)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	255
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ASB9_MOUSE
NC score	0.705613 (rank : 87)	θ value	5.81887e-07 (rank : 140)
Query Neighborhood Hits	1041	Target Neighborhood Hits	257	Shared Neighborhood Hits	243
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

PP16A_MOUSE
NC score	0.705595 (rank : 88)	θ value	3.41135e-07 (rank : 137)
Query Neighborhood Hits	1041	Target Neighborhood Hits	318	Shared Neighborhood Hits	270
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ASB14_MOUSE
NC score	0.704378 (rank : 89)	θ value	2.21117e-06 (rank : 155)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	264
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

EHMT1_HUMAN
NC score	0.703491 (rank : 90)	θ value	1.09485e-13 (rank : 32)
Query Neighborhood Hits	1041	Target Neighborhood Hits	417	Shared Neighborhood Hits	286
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANR10_HUMAN
NC score	0.703008 (rank : 91)	θ value	9.92553e-07 (rank : 144)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	262
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANRA2_HUMAN
NC score	0.702009 (rank : 92)	θ value	5.26297e-08 (rank : 112)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	260
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

EHMT2_HUMAN
NC score	0.701648 (rank : 93)	θ value	1.80466e-16 (rank : 20)
Query Neighborhood Hits	1041	Target Neighborhood Hits	498	Shared Neighborhood Hits	299
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

CDN2C_HUMAN
NC score	0.701297 (rank : 94)	θ value	4.1701e-05 (rank : 207)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	251
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANRA2_MOUSE
NC score	0.701268 (rank : 95)	θ value	1.99992e-07 (rank : 123)
Query Neighborhood Hits	1041	Target Neighborhood Hits	287	Shared Neighborhood Hits	259
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR10_MOUSE
NC score	0.701174 (rank : 96)	θ value	2.21117e-06 (rank : 154)
Query Neighborhood Hits	1041	Target Neighborhood Hits	273	Shared Neighborhood Hits	263
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

RN5A_HUMAN
NC score	0.700919 (rank : 97)	θ value	6.21693e-09 (rank : 102)
Query Neighborhood Hits	1041	Target Neighborhood Hits	608	Shared Neighborhood Hits	288
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANKR5_HUMAN
NC score	0.700304 (rank : 98)	θ value	2.21117e-06 (rank : 153)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	267
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

IKBE_MOUSE
NC score	0.699649 (rank : 99)	θ value	2.88788e-06 (rank : 158)
Query Neighborhood Hits	1041	Target Neighborhood Hits	308	Shared Neighborhood Hits	275
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR46_HUMAN
NC score	0.699455 (rank : 100)	θ value	1.09739e-05 (rank : 183)
Query Neighborhood Hits	1041	Target Neighborhood Hits	281	Shared Neighborhood Hits	263
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

EHMT2_MOUSE
NC score	0.699296 (rank : 101)	θ value	6.20254e-17 (rank : 17)
Query Neighborhood Hits	1041	Target Neighborhood Hits	750	Shared Neighborhood Hits	372
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PP16A_HUMAN
NC score	0.699274 (rank : 102)	θ value	1.09739e-05 (rank : 187)
Query Neighborhood Hits	1041	Target Neighborhood Hits	340	Shared Neighborhood Hits	275
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

CDN2C_MOUSE
NC score	0.698513 (rank : 103)	θ value	9.29e-05 (rank : 220)
Query Neighborhood Hits	1041	Target Neighborhood Hits	270	Shared Neighborhood Hits	256
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

MYPT2_HUMAN
NC score	0.698460 (rank : 104)	θ value	1.25267e-09 (rank : 87)
Query Neighborhood Hits	1041	Target Neighborhood Hits	707	Shared Neighborhood Hits	303
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

IKBA_MOUSE
NC score	0.698275 (rank : 105)	θ value	3.41135e-07 (rank : 133)
Query Neighborhood Hits	1041	Target Neighborhood Hits	283	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANR46_MOUSE
NC score	0.697964 (rank : 106)	θ value	9.92553e-07 (rank : 145)
Query Neighborhood Hits	1041	Target Neighborhood Hits	274	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANKR5_MOUSE
NC score	0.697739 (rank : 107)	θ value	0.000461057 (rank : 261)
Query Neighborhood Hits	1041	Target Neighborhood Hits	298	Shared Neighborhood Hits	270
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

AN36B_HUMAN
NC score	0.697676 (rank : 108)	θ value	8.40245e-06 (rank : 176)
Query Neighborhood Hits	1041	Target Neighborhood Hits	294	Shared Neighborhood Hits	265
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

MIB2_MOUSE
NC score	0.696668 (rank : 109)	θ value	5.26297e-08 (rank : 113)
Query Neighborhood Hits	1041	Target Neighborhood Hits	409	Shared Neighborhood Hits	270
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANR35_HUMAN
NC score	0.696592 (rank : 110)	θ value	2.69671e-12 (rank : 49)
Query Neighborhood Hits	1041	Target Neighborhood Hits	784	Shared Neighborhood Hits	306
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

MIB2_HUMAN
NC score	0.695859 (rank : 111)	θ value	7.1131e-05 (rank : 218)
Query Neighborhood Hits	1041	Target Neighborhood Hits	438	Shared Neighborhood Hits	274
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MYPT1_HUMAN
NC score	0.695747 (rank : 112)	θ value	1.63604e-09 (rank : 89)
Query Neighborhood Hits	1041	Target Neighborhood Hits	723	Shared Neighborhood Hits	310
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ASB1_HUMAN
NC score	0.695414 (rank : 113)	θ value	2.44474e-05 (rank : 198)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_MOUSE
NC score	0.694124 (rank : 114)	θ value	8.40245e-06 (rank : 178)
Query Neighborhood Hits	1041	Target Neighborhood Hits	292	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB12_HUMAN
NC score	0.692815 (rank : 115)	θ value	6.43352e-06 (rank : 173)
Query Neighborhood Hits	1041	Target Neighborhood Hits	263	Shared Neighborhood Hits	253
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

RFXK_HUMAN
NC score	0.692372 (rank : 116)	θ value	0.000270298 (rank : 246)
Query Neighborhood Hits	1041	Target Neighborhood Hits	282	Shared Neighborhood Hits	258
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

PP16B_HUMAN
NC score	0.691595 (rank : 117)	θ value	5.44631e-05 (rank : 213)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	273
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

CDN2D_HUMAN
NC score	0.691274 (rank : 118)	θ value	0.00175202 (rank : 303)
Query Neighborhood Hits	1041	Target Neighborhood Hits	268	Shared Neighborhood Hits	254
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

PP16B_MOUSE
NC score	0.689639 (rank : 119)	θ value	0.000158464 (rank : 235)
Query Neighborhood Hits	1041	Target Neighborhood Hits	302	Shared Neighborhood Hits	272
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

CDN2D_MOUSE
NC score	0.688720 (rank : 120)	θ value	0.000461057 (rank : 263)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	253
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB12_MOUSE
NC score	0.687936 (rank : 121)	θ value	7.1131e-05 (rank : 216)
Query Neighborhood Hits	1041	Target Neighborhood Hits	261	Shared Neighborhood Hits	251
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

RFXK_MOUSE
NC score	0.687785 (rank : 122)	θ value	0.00020696 (rank : 237)
Query Neighborhood Hits	1041	Target Neighborhood Hits	273	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ANR22_HUMAN
NC score	0.687059 (rank : 123)	θ value	0.365318 (rank : 527)
Query Neighborhood Hits	1041	Target Neighborhood Hits	243	Shared Neighborhood Hits	238
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

IKBE_HUMAN
NC score	0.684064 (rank : 124)	θ value	4.1701e-05 (rank : 209)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	262
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ACBD6_MOUSE
NC score	0.683963 (rank : 125)	θ value	4.45536e-07 (rank : 138)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	271
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ACBD6_HUMAN
NC score	0.679605 (rank : 126)	θ value	1.09739e-05 (rank : 181)
Query Neighborhood Hits	1041	Target Neighborhood Hits	304	Shared Neighborhood Hits	268
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

POTE8_HUMAN
NC score	0.678443 (rank : 127)	θ value	1.06045e-08 (rank : 107)
Query Neighborhood Hits	1041	Target Neighborhood Hits	337	Shared Neighborhood Hits	267
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

BARD1_HUMAN
NC score	0.674799 (rank : 128)	θ value	3.41135e-07 (rank : 132)
Query Neighborhood Hits	1041	Target Neighborhood Hits	427	Shared Neighborhood Hits	273
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

IKBB_MOUSE
NC score	0.672863 (rank : 129)	θ value	0.00035302 (rank : 252)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	264
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

IKBB_HUMAN
NC score	0.672201 (rank : 130)	θ value	0.00102713 (rank : 287)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	267
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

BARD1_MOUSE
NC score	0.672177 (rank : 131)	θ value	1.99992e-07 (rank : 127)
Query Neighborhood Hits	1041	Target Neighborhood Hits	411	Shared Neighborhood Hits	270
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR19_HUMAN
NC score	0.672102 (rank : 132)	θ value	4.1701e-05 (rank : 206)
Query Neighborhood Hits	1041	Target Neighborhood Hits	276	Shared Neighborhood Hits	258
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

AN36A_HUMAN
NC score	0.671767 (rank : 133)	θ value	0.000270298 (rank : 239)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR11_HUMAN
NC score	0.667450 (rank : 134)	θ value	8.67504e-11 (rank : 70)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1289	Shared Neighborhood Hits	414
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

OSTF1_MOUSE
NC score	0.665546 (rank : 135)	θ value	0.00035302 (rank : 256)
Query Neighborhood Hits	1041	Target Neighborhood Hits	467	Shared Neighborhood Hits	370
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANR41_HUMAN
NC score	0.664593 (rank : 136)	θ value	1.53129e-07 (rank : 120)
Query Neighborhood Hits	1041	Target Neighborhood Hits	332	Shared Neighborhood Hits	265
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

RN5A_MOUSE
NC score	0.661406 (rank : 137)	θ value	3.29651e-10 (rank : 77)
Query Neighborhood Hits	1041	Target Neighborhood Hits	899	Shared Neighborhood Hits	306
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

CTTB2_HUMAN
NC score	0.660155 (rank : 138)	θ value	2.43908e-13 (rank : 40)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1061	Shared Neighborhood Hits	359
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANFY1_MOUSE
NC score	0.659916 (rank : 139)	θ value	6.21693e-09 (rank : 99)
Query Neighborhood Hits	1041	Target Neighborhood Hits	480	Shared Neighborhood Hits	276
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.659559 (rank : 140)	θ value	4.76016e-09 (rank : 97)
Query Neighborhood Hits	1041	Target Neighborhood Hits	480	Shared Neighborhood Hits	276
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

OSTF1_HUMAN
NC score	0.654034 (rank : 141)	θ value	0.000461057 (rank : 269)
Query Neighborhood Hits	1041	Target Neighborhood Hits	466	Shared Neighborhood Hits	370
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ASB6_HUMAN
NC score	0.652677 (rank : 142)	θ value	7.1131e-05 (rank : 217)
Query Neighborhood Hits	1041	Target Neighborhood Hits	256	Shared Neighborhood Hits	238
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB6_MOUSE
NC score	0.652476 (rank : 143)	θ value	3.19293e-05 (rank : 201)
Query Neighborhood Hits	1041	Target Neighborhood Hits	264	Shared Neighborhood Hits	237
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

USH1G_MOUSE
NC score	0.645511 (rank : 144)	θ value	0.00102713 (rank : 292)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	251
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.645265 (rank : 145)	θ value	0.00102713 (rank : 291)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	250
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ANS4B_HUMAN
NC score	0.643565 (rank : 146)	θ value	0.00298849 (rank : 322)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH17_HUMAN
NC score	0.642596 (rank : 147)	θ value	7.59969e-07 (rank : 143)
Query Neighborhood Hits	1041	Target Neighborhood Hits	334	Shared Neighborhood Hits	268
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR32_HUMAN
NC score	0.642246 (rank : 148)	θ value	0.0193708 (rank : 392)
Query Neighborhood Hits	1041	Target Neighborhood Hits	270	Shared Neighborhood Hits	249
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANKY2_HUMAN
NC score	0.642155 (rank : 149)	θ value	4.92598e-06 (rank : 166)
Query Neighborhood Hits	1041	Target Neighborhood Hits	306	Shared Neighborhood Hits	250
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

POT15_HUMAN
NC score	0.641933 (rank : 150)	θ value	1.06045e-08 (rank : 106)
Query Neighborhood Hits	1041	Target Neighborhood Hits	893	Shared Neighborhood Hits	309
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANR21_HUMAN
NC score	0.639437 (rank : 151)	θ value	6.87365e-08 (rank : 114)
Query Neighborhood Hits	1041	Target Neighborhood Hits	864	Shared Neighborhood Hits	308
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ZDH13_HUMAN
NC score	0.637175 (rank : 152)	θ value	1.09739e-05 (rank : 188)
Query Neighborhood Hits	1041	Target Neighborhood Hits	322	Shared Neighborhood Hits	267
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ZDH17_MOUSE
NC score	0.637076 (rank : 153)	θ value	1.09739e-05 (rank : 189)
Query Neighborhood Hits	1041	Target Neighborhood Hits	328	Shared Neighborhood Hits	265
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ZDH13_MOUSE
NC score	0.633613 (rank : 154)	θ value	1.87187e-05 (rank : 196)
Query Neighborhood Hits	1041	Target Neighborhood Hits	329	Shared Neighborhood Hits	270
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANR32_MOUSE
NC score	0.632540 (rank : 155)	θ value	0.163984 (rank : 491)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	250
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANS4B_MOUSE
NC score	0.630249 (rank : 156)	θ value	0.0431538 (rank : 418)
Query Neighborhood Hits	1041	Target Neighborhood Hits	294	Shared Neighborhood Hits	248
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

NFKB2_HUMAN
NC score	0.626156 (rank : 157)	θ value	3.41135e-07 (rank : 134)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	274
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

POT14_HUMAN
NC score	0.625018 (rank : 158)	θ value	5.81887e-07 (rank : 141)
Query Neighborhood Hits	1041	Target Neighborhood Hits	403	Shared Neighborhood Hits	270
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANKY2_MOUSE
NC score	0.623056 (rank : 159)	θ value	2.88788e-06 (rank : 157)
Query Neighborhood Hits	1041	Target Neighborhood Hits	316	Shared Neighborhood Hits	248
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR47_MOUSE
NC score	0.623016 (rank : 160)	θ value	6.43352e-06 (rank : 172)
Query Neighborhood Hits	1041	Target Neighborhood Hits	350	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NFKB1_MOUSE
NC score	0.621829 (rank : 161)	θ value	0.000121331 (rank : 227)
Query Neighborhood Hits	1041	Target Neighborhood Hits	300	Shared Neighborhood Hits	262
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANR12_HUMAN
NC score	0.620707 (rank : 162)	θ value	8.11959e-09 (rank : 103)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1081	Shared Neighborhood Hits	323
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

NFKB1_HUMAN
NC score	0.619924 (rank : 163)	θ value	0.000158464 (rank : 232)
Query Neighborhood Hits	1041	Target Neighborhood Hits	306	Shared Neighborhood Hits	269
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANR15_HUMAN
NC score	0.617120 (rank : 164)	θ value	0.00035302 (rank : 249)
Query Neighborhood Hits	1041	Target Neighborhood Hits	478	Shared Neighborhood Hits	277
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR37_HUMAN
NC score	0.614875 (rank : 165)	θ value	0.47712 (rank : 552)
Query Neighborhood Hits	1041	Target Neighborhood Hits	247	Shared Neighborhood Hits	242
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

NFKB2_MOUSE
NC score	0.613844 (rank : 166)	θ value	3.41135e-07 (rank : 135)
Query Neighborhood Hits	1041	Target Neighborhood Hits	326	Shared Neighborhood Hits	267
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR47_HUMAN
NC score	0.611312 (rank : 167)	θ value	1.87187e-05 (rank : 192)
Query Neighborhood Hits	1041	Target Neighborhood Hits	369	Shared Neighborhood Hits	275
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

BCOR_MOUSE
NC score	0.608651 (rank : 168)	θ value	0.00035302 (rank : 251)
Query Neighborhood Hits	1041	Target Neighborhood Hits	521	Shared Neighborhood Hits	305
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

SNCAP_HUMAN
NC score	0.606934 (rank : 169)	θ value	0.0252991 (rank : 404)
Query Neighborhood Hits	1041	Target Neighborhood Hits	313	Shared Neighborhood Hits	241
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

BCOR_HUMAN
NC score	0.602972 (rank : 170)	θ value	0.00035302 (rank : 250)
Query Neighborhood Hits	1041	Target Neighborhood Hits	609	Shared Neighborhood Hits	325
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR37_MOUSE
NC score	0.598779 (rank : 171)	θ value	1.38821 (rank : 661)
Query Neighborhood Hits	1041	Target Neighborhood Hits	237	Shared Neighborhood Hits	232
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR33_MOUSE
NC score	0.591186 (rank : 172)	θ value	0.00390308 (rank : 331)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	218
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CLPB_MOUSE
NC score	0.591140 (rank : 173)	θ value	0.00509761 (rank : 342)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	242
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

POT22_HUMAN
NC score	0.588906 (rank : 174)	θ value	0.000158464 (rank : 234)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	251
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

A20A3_HUMAN
NC score	0.586513 (rank : 175)	θ value	2.21117e-06 (rank : 151)
Query Neighborhood Hits	1041	Target Neighborhood Hits	692	Shared Neighborhood Hits	295
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.585078 (rank : 176)	θ value	3.77169e-06 (rank : 163)
Query Neighborhood Hits	1041	Target Neighborhood Hits	716	Shared Neighborhood Hits	291
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.584631 (rank : 177)	θ value	6.43352e-06 (rank : 171)
Query Neighborhood Hits	1041	Target Neighborhood Hits	698	Shared Neighborhood Hits	292
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

MPP8_HUMAN
NC score	0.583780 (rank : 178)	θ value	0.000461057 (rank : 268)
Query Neighborhood Hits	1041	Target Neighborhood Hits	948	Shared Neighborhood Hits	294
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

A20A4_HUMAN
NC score	0.582877 (rank : 179)	θ value	2.21117e-06 (rank : 152)
Query Neighborhood Hits	1041	Target Neighborhood Hits	710	Shared Neighborhood Hits	295
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

CD2A1_MOUSE
NC score	0.579681 (rank : 180)	θ value	3.0926 (rank : 783)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	196
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ANR33_HUMAN
NC score	0.577550 (rank : 181)	θ value	0.0736092 (rank : 445)
Query Neighborhood Hits	1041	Target Neighborhood Hits	215	Shared Neighborhood Hits	211
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR25_HUMAN
NC score	0.575158 (rank : 182)	θ value	0.00228821 (rank : 309)
Query Neighborhood Hits	1041	Target Neighborhood Hits	350	Shared Neighborhood Hits	266
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

OSBL1_HUMAN
NC score	0.571445 (rank : 183)	θ value	3.41135e-07 (rank : 136)
Query Neighborhood Hits	1041	Target Neighborhood Hits	368	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

RAI14_HUMAN
NC score	0.569934 (rank : 184)	θ value	8.10077e-17 (rank : 18)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1367	Shared Neighborhood Hits	350
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR25_MOUSE
NC score	0.566239 (rank : 185)	θ value	0.0113563 (rank : 365)
Query Neighborhood Hits	1041	Target Neighborhood Hits	398	Shared Neighborhood Hits	281
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

KRIT1_MOUSE
NC score	0.564753 (rank : 186)	θ value	0.125558 (rank : 485)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	224
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

OSBL1_MOUSE
NC score	0.561690 (rank : 187)	θ value	9.92553e-07 (rank : 146)
Query Neighborhood Hits	1041	Target Neighborhood Hits	336	Shared Neighborhood Hits	269
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

KRIT1_HUMAN
NC score	0.559286 (rank : 188)	θ value	0.0330416 (rank : 409)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	218
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

IASPP_HUMAN
NC score	0.558239 (rank : 189)	θ value	0.125558 (rank : 484)
Query Neighborhood Hits	1041	Target Neighborhood Hits	688	Shared Neighborhood Hits	460
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANR38_HUMAN
NC score	0.553407 (rank : 190)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	1041	Target Neighborhood Hits	443	Shared Neighborhood Hits	260
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR18_HUMAN
NC score	0.549168 (rank : 191)	θ value	1.09739e-05 (rank : 182)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1106	Shared Neighborhood Hits	312
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASPP1_HUMAN
NC score	0.545965 (rank : 192)	θ value	0.00869519 (rank : 353)
Query Neighborhood Hits	1041	Target Neighborhood Hits	956	Shared Neighborhood Hits	459
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RAI14_MOUSE
NC score	0.542284 (rank : 193)	θ value	6.85773e-16 (rank : 23)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1505	Shared Neighborhood Hits	360
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR38_MOUSE
NC score	0.541622 (rank : 194)	θ value	0.163984 (rank : 492)
Query Neighborhood Hits	1041	Target Neighborhood Hits	512	Shared Neighborhood Hits	264
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASPP1_MOUSE
NC score	0.538186 (rank : 195)	θ value	0.00869519 (rank : 354)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1244	Shared Neighborhood Hits	514
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CDN2B_MOUSE
NC score	0.536675 (rank : 196)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	1041	Target Neighborhood Hits	201	Shared Neighborhood Hits	192
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

ASPP2_HUMAN
NC score	0.532007 (rank : 197)	θ value	0.00390308 (rank : 332)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1156	Shared Neighborhood Hits	465
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANR40_HUMAN
NC score	0.515730 (rank : 198)	θ value	0.163984 (rank : 493)
Query Neighborhood Hits	1041	Target Neighborhood Hits	224	Shared Neighborhood Hits	211
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

AN30A_HUMAN
NC score	0.515531 (rank : 199)	θ value	0.00298849 (rank : 321)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1119	Shared Neighborhood Hits	324
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

IASPP_MOUSE
NC score	0.514294 (rank : 200)	θ value	0.0113563 (rank : 369)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1024	Shared Neighborhood Hits	500
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANKK1_HUMAN
NC score	0.512194 (rank : 201)	θ value	2.43343e-21 (rank : 5)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1075	Shared Neighborhood Hits	326
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR40_MOUSE
NC score	0.511305 (rank : 202)	θ value	0.365318 (rank : 528)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	217
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CLPB_HUMAN
NC score	0.511091 (rank : 203)	θ value	0.0431538 (rank : 419)
Query Neighborhood Hits	1041	Target Neighborhood Hits	265	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

HECD1_HUMAN
NC score	0.510905 (rank : 204)	θ value	0.0148317 (rank : 385)
Query Neighborhood Hits	1041	Target Neighborhood Hits	371	Shared Neighborhood Hits	265
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

SHAN2_MOUSE
NC score	0.505642 (rank : 205)	θ value	1.17455e-116 (rank : 2)
Query Neighborhood Hits	1041	Target Neighborhood Hits	446	Shared Neighborhood Hits	305
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

CDN2B_HUMAN
NC score	0.503056 (rank : 206)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	1041	Target Neighborhood Hits	196	Shared Neighborhood Hits	189
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ANR45_MOUSE
NC score	0.501045 (rank : 207)	θ value	1.81305 (rank : 687)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	187
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

CD2A1_HUMAN
NC score	0.500156 (rank : 208)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	1041	Target Neighborhood Hits	196	Shared Neighborhood Hits	184
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANKK1_MOUSE
NC score	0.499402 (rank : 209)	θ value	5.07402e-19 (rank : 10)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1072	Shared Neighborhood Hits	325
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR43_HUMAN
NC score	0.497814 (rank : 210)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	1041	Target Neighborhood Hits	209	Shared Neighborhood Hits	197
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

RIPK4_HUMAN
NC score	0.495740 (rank : 211)	θ value	1.02475e-11 (rank : 61)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1094	Shared Neighborhood Hits	326
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANR43_MOUSE
NC score	0.488722 (rank : 212)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	1041	Target Neighborhood Hits	214	Shared Neighborhood Hits	200
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CENB5_HUMAN
NC score	0.487386 (rank : 213)	θ value	8.40245e-06 (rank : 179)
Query Neighborhood Hits	1041	Target Neighborhood Hits	395	Shared Neighborhood Hits	265
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

TRPV6_MOUSE
NC score	0.486262 (rank : 214)	θ value	7.59969e-07 (rank : 142)
Query Neighborhood Hits	1041	Target Neighborhood Hits	284	Shared Neighborhood Hits	237
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

NUD12_MOUSE
NC score	0.481746 (rank : 215)	θ value	0.0193708 (rank : 395)
Query Neighborhood Hits	1041	Target Neighborhood Hits	243	Shared Neighborhood Hits	218
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ABTB2_HUMAN
NC score	0.479541 (rank : 216)	θ value	0.279714 (rank : 516)
Query Neighborhood Hits	1041	Target Neighborhood Hits	391	Shared Neighborhood Hits	230
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

CENB1_HUMAN
NC score	0.478256 (rank : 217)	θ value	0.0736092 (rank : 447)
Query Neighborhood Hits	1041	Target Neighborhood Hits	383	Shared Neighborhood Hits	265
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ILK2_HUMAN
NC score	0.477493 (rank : 218)	θ value	1.99992e-07 (rank : 129)
Query Neighborhood Hits	1041	Target Neighborhood Hits	848	Shared Neighborhood Hits	313
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

CENB2_HUMAN
NC score	0.471444 (rank : 219)	θ value	0.00102713 (rank : 284)
Query Neighborhood Hits	1041	Target Neighborhood Hits	425	Shared Neighborhood Hits	255
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ANR45_HUMAN
NC score	0.469073 (rank : 220)	θ value	5.27518 (rank : 871)
Query Neighborhood Hits	1041	Target Neighborhood Hits	201	Shared Neighborhood Hits	182
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ABTB2_MOUSE
NC score	0.468355 (rank : 221)	θ value	0.813845 (rank : 603)
Query Neighborhood Hits	1041	Target Neighborhood Hits	414	Shared Neighborhood Hits	229
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANKY1_HUMAN
NC score	0.467986 (rank : 222)	θ value	2.36792 (rank : 728)
Query Neighborhood Hits	1041	Target Neighborhood Hits	248	Shared Neighborhood Hits	202
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ASB14_HUMAN
NC score	0.466538 (rank : 223)	θ value	6.88961 (rank : 919)
Query Neighborhood Hits	1041	Target Neighborhood Hits	187	Shared Neighborhood Hits	170
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ILK1_HUMAN
NC score	0.462328 (rank : 224)	θ value	1.99992e-07 (rank : 128)
Query Neighborhood Hits	1041	Target Neighborhood Hits	857	Shared Neighborhood Hits	313
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.461484 (rank : 225)	θ value	1.17247e-07 (rank : 119)
Query Neighborhood Hits	1041	Target Neighborhood Hits	858	Shared Neighborhood Hits	313
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

AN13B_MOUSE
NC score	0.460435 (rank : 226)	θ value	0.00102713 (rank : 282)
Query Neighborhood Hits	1041	Target Neighborhood Hits	276	Shared Neighborhood Hits	249
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.459223 (rank : 227)	θ value	0.00102713 (rank : 281)
Query Neighborhood Hits	1041	Target Neighborhood Hits	265	Shared Neighborhood Hits	247
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13C_HUMAN
NC score	0.458836 (rank : 228)	θ value	0.00035302 (rank : 248)
Query Neighborhood Hits	1041	Target Neighborhood Hits	241	Shared Neighborhood Hits	232
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

NUD12_HUMAN
NC score	0.455517 (rank : 229)	θ value	0.00869519 (rank : 362)
Query Neighborhood Hits	1041	Target Neighborhood Hits	222	Shared Neighborhood Hits	196
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

GIT2_MOUSE
NC score	0.453691 (rank : 230)	θ value	0.0193708 (rank : 393)
Query Neighborhood Hits	1041	Target Neighborhood Hits	323	Shared Neighborhood Hits	254
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

UACA_HUMAN
NC score	0.453627 (rank : 231)	θ value	2.13673e-09 (rank : 92)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1622	Shared Neighborhood Hits	340
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AN13C_MOUSE
NC score	0.448363 (rank : 232)	θ value	0.00102713 (rank : 283)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	231
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

SHAN2_HUMAN
NC score	0.448209 (rank : 233)	θ value	3.02872e-72 (rank : 3)
Query Neighborhood Hits	1041	Target Neighborhood Hits	346	Shared Neighborhood Hits	208
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

GIT1_MOUSE
NC score	0.445326 (rank : 234)	θ value	0.00102713 (rank : 286)
Query Neighborhood Hits	1041	Target Neighborhood Hits	341	Shared Neighborhood Hits	248
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.443646 (rank : 235)	θ value	0.00102713 (rank : 285)
Query Neighborhood Hits	1041	Target Neighborhood Hits	336	Shared Neighborhood Hits	245
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

TRPV5_MOUSE
NC score	0.443080 (rank : 236)	θ value	3.19293e-05 (rank : 204)
Query Neighborhood Hits	1041	Target Neighborhood Hits	278	Shared Neighborhood Hits	233
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

UACA_MOUSE
NC score	0.434031 (rank : 237)	θ value	1.63604e-09 (rank : 90)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1620	Shared Neighborhood Hits	340
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

NOTC4_MOUSE
NC score	0.423857 (rank : 238)	θ value	2.13179e-17 (rank : 15)
Query Neighborhood Hits	1041	Target Neighborhood Hits	872	Shared Neighborhood Hits	293
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

GIT2_HUMAN
NC score	0.422891 (rank : 239)	θ value	0.00390308 (rank : 333)
Query Neighborhood Hits	1041	Target Neighborhood Hits	381	Shared Neighborhood Hits	256
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

ANR26_MOUSE
NC score	0.419452 (rank : 240)	θ value	1.25267e-09 (rank : 84)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1554	Shared Neighborhood Hits	349
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC4_HUMAN
NC score	0.418388 (rank : 241)	θ value	1.80466e-16 (rank : 21)
Query Neighborhood Hits	1041	Target Neighborhood Hits	905	Shared Neighborhood Hits	298
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRPV5_HUMAN
NC score	0.417028 (rank : 242)	θ value	0.000461057 (rank : 273)
Query Neighborhood Hits	1041	Target Neighborhood Hits	261	Shared Neighborhood Hits	208
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

DDEF2_HUMAN
NC score	0.415637 (rank : 243)	θ value	0.00298849 (rank : 324)
Query Neighborhood Hits	1041	Target Neighborhood Hits	599	Shared Neighborhood Hits	401
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TRPV6_HUMAN
NC score	0.414486 (rank : 244)	θ value	0.000602161 (rank : 275)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	210
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

DDEF2_MOUSE
NC score	0.412535 (rank : 245)	θ value	0.00298849 (rank : 325)
Query Neighborhood Hits	1041	Target Neighborhood Hits	625	Shared Neighborhood Hits	394
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_MOUSE
NC score	0.411474 (rank : 246)	θ value	0.0148317 (rank : 382)
Query Neighborhood Hits	1041	Target Neighborhood Hits	324	Shared Neighborhood Hits	249
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

TNI3K_HUMAN
NC score	0.403757 (rank : 247)	θ value	1.33837e-11 (rank : 62)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1084	Shared Neighborhood Hits	326
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANR26_HUMAN
NC score	0.399749 (rank : 248)	θ value	2.79066e-09 (rank : 93)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1614	Shared Neighborhood Hits	344
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TNI3K_MOUSE
NC score	0.399195 (rank : 249)	θ value	1.86753e-13 (rank : 39)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1079	Shared Neighborhood Hits	327
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

GLSL_HUMAN
NC score	0.399019 (rank : 250)	θ value	θ > 10 (rank : 1205)
Query Neighborhood Hits	1041	Target Neighborhood Hits	211	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AN13A_HUMAN
NC score	0.394703 (rank : 251)	θ value	0.47712 (rank : 551)
Query Neighborhood Hits	1041	Target Neighborhood Hits	243	Shared Neighborhood Hits	214
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

NOTC3_MOUSE
NC score	0.389954 (rank : 252)	θ value	1.16975e-15 (rank : 27)
Query Neighborhood Hits	1041	Target Neighborhood Hits	975	Shared Neighborhood Hits	329
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

GLSL_MOUSE
NC score	0.388097 (rank : 253)	θ value	θ > 10 (rank : 1206)
Query Neighborhood Hits	1041	Target Neighborhood Hits	212	Shared Neighborhood Hits	194
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

NOTC3_HUMAN
NC score	0.387779 (rank : 254)	θ value	1.16975e-15 (rank : 26)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1062	Shared Neighborhood Hits	341
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TEX14_HUMAN
NC score	0.385616 (rank : 255)	θ value	4.1701e-05 (rank : 211)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1103	Shared Neighborhood Hits	330
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NOTC2_HUMAN
NC score	0.385346 (rank : 256)	θ value	3.52202e-12 (rank : 50)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1113	Shared Neighborhood Hits	352
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CT012_MOUSE
NC score	0.384173 (rank : 257)	θ value	0.62314 (rank : 587)
Query Neighborhood Hits	1041	Target Neighborhood Hits	229	Shared Neighborhood Hits	177
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

NOTC1_HUMAN
NC score	0.382249 (rank : 258)	θ value	1.09485e-13 (rank : 35)
Query Neighborhood Hits	1041	Target Neighborhood Hits	906	Shared Neighborhood Hits	303
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TEX14_MOUSE
NC score	0.381511 (rank : 259)	θ value	0.00134147 (rank : 301)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1333	Shared Neighborhood Hits	344
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NOTC2_MOUSE
NC score	0.381050 (rank : 260)	θ value	9.26847e-13 (rank : 44)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1069	Shared Neighborhood Hits	326
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

AN13A_MOUSE
NC score	0.372348 (rank : 261)	θ value	0.62314 (rank : 582)
Query Neighborhood Hits	1041	Target Neighborhood Hits	226	Shared Neighborhood Hits	213
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

GLSK_HUMAN
NC score	0.364442 (rank : 262)	θ value	θ > 10 (rank : 1204)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	184
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

DAPK1_MOUSE
NC score	0.360868 (rank : 263)	θ value	1.16975e-15 (rank : 25)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1138	Shared Neighborhood Hits	327
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_HUMAN
NC score	0.352316 (rank : 264)	θ value	7.84624e-12 (rank : 59)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1130	Shared Neighborhood Hits	325
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DDFL1_HUMAN
NC score	0.343336 (rank : 265)	θ value	0.00228821 (rank : 312)
Query Neighborhood Hits	1041	Target Neighborhood Hits	353	Shared Neighborhood Hits	257
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

CT012_HUMAN
NC score	0.341839 (rank : 266)	θ value	6.88961 (rank : 932)
Query Neighborhood Hits	1041	Target Neighborhood Hits	205	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DDEF1_MOUSE
NC score	0.339226 (rank : 267)	θ value	0.000121331 (rank : 226)
Query Neighborhood Hits	1041	Target Neighborhood Hits	592	Shared Neighborhood Hits	346
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CENG1_MOUSE
NC score	0.335905 (rank : 268)	θ value	0.0148317 (rank : 380)
Query Neighborhood Hits	1041	Target Neighborhood Hits	531	Shared Neighborhood Hits	300
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

DGKZ_HUMAN
NC score	0.334014 (rank : 269)	θ value	0.125558 (rank : 478)
Query Neighborhood Hits	1041	Target Neighborhood Hits	551	Shared Neighborhood Hits	219
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_HUMAN
NC score	0.333990 (rank : 270)	θ value	0.0148317 (rank : 379)
Query Neighborhood Hits	1041	Target Neighborhood Hits	544	Shared Neighborhood Hits	300
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

NOTC1_MOUSE
NC score	0.332466 (rank : 271)	θ value	5.62301e-10 (rank : 80)
Query Neighborhood Hits	1041	Target Neighborhood Hits	916	Shared Neighborhood Hits	293
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

IKBL_HUMAN
NC score	0.328840 (rank : 272)	θ value	0.0113563 (rank : 370)
Query Neighborhood Hits	1041	Target Neighborhood Hits	168	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
NC score	0.322661 (rank : 273)	θ value	0.0113563 (rank : 371)
Query Neighborhood Hits	1041	Target Neighborhood Hits	196	Shared Neighborhood Hits	146
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

DGKZ_MOUSE
NC score	0.319571 (rank : 274)	θ value	0.0330416 (rank : 408)
Query Neighborhood Hits	1041	Target Neighborhood Hits	542	Shared Neighborhood Hits	207
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG2_HUMAN
NC score	0.317274 (rank : 275)	θ value	0.0113563 (rank : 367)
Query Neighborhood Hits	1041	Target Neighborhood Hits	471	Shared Neighborhood Hits	250
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
NC score	0.314971 (rank : 276)	θ value	0.0148317 (rank : 381)
Query Neighborhood Hits	1041	Target Neighborhood Hits	463	Shared Neighborhood Hits	246
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DGKI_HUMAN
NC score	0.311899 (rank : 277)	θ value	0.0148317 (rank : 383)
Query Neighborhood Hits	1041	Target Neighborhood Hits	609	Shared Neighborhood Hits	220
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

ANKZ1_MOUSE
NC score	0.301515 (rank : 278)	θ value	0.0431538 (rank : 417)
Query Neighborhood Hits	1041	Target Neighborhood Hits	208	Shared Neighborhood Hits	158
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CENG3_MOUSE
NC score	0.291201 (rank : 279)	θ value	0.47712 (rank : 557)
Query Neighborhood Hits	1041	Target Neighborhood Hits	467	Shared Neighborhood Hits	235
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.291154 (rank : 280)	θ value	0.47712 (rank : 556)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	235
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ANKZ1_HUMAN
NC score	0.280571 (rank : 281)	θ value	2.36792 (rank : 729)
Query Neighborhood Hits	1041	Target Neighborhood Hits	236	Shared Neighborhood Hits	164
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

NHERF_HUMAN
NC score	0.276211 (rank : 282)	θ value	8.11959e-09 (rank : 104)
Query Neighborhood Hits	1041	Target Neighborhood Hits	190	Shared Neighborhood Hits	139
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
NC score	0.275421 (rank : 283)	θ value	8.97725e-08 (rank : 116)
Query Neighborhood Hits	1041	Target Neighborhood Hits	195	Shared Neighborhood Hits	139
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD1_MOUSE
NC score	0.267543 (rank : 284)	θ value	3.77169e-06 (rank : 165)
Query Neighborhood Hits	1041	Target Neighborhood Hits	191	Shared Neighborhood Hits	137
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ANKR9_MOUSE
NC score	0.266781 (rank : 285)	θ value	1.06291 (rank : 634)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

PDZD1_HUMAN
NC score	0.266758 (rank : 286)	θ value	1.53129e-07 (rank : 121)
Query Neighborhood Hits	1041	Target Neighborhood Hits	190	Shared Neighborhood Hits	138
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHRF2_HUMAN
NC score	0.266148 (rank : 287)	θ value	2.21117e-06 (rank : 156)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	138
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
NC score	0.259900 (rank : 288)	θ value	1.87187e-05 (rank : 195)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PDZD3_MOUSE
NC score	0.251826 (rank : 289)	θ value	7.1131e-05 (rank : 219)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	132
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

CLR59_HUMAN
NC score	0.251301 (rank : 290)	θ value	4.03905 (rank : 830)
Query Neighborhood Hits	1041	Target Neighborhood Hits	163	Shared Neighborhood Hits	142
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

PDZD3_HUMAN
NC score	0.246463 (rank : 291)	θ value	9.29e-05 (rank : 224)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	136
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

ABTB1_MOUSE
NC score	0.242629 (rank : 292)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	171
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

USH1C_MOUSE
NC score	0.239577 (rank : 293)	θ value	6.43352e-06 (rank : 175)
Query Neighborhood Hits	1041	Target Neighborhood Hits	557	Shared Neighborhood Hits	209
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

GRASP_HUMAN
NC score	0.239545 (rank : 294)	θ value	1.87187e-05 (rank : 194)
Query Neighborhood Hits	1041	Target Neighborhood Hits	147	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

WHRN_MOUSE
NC score	0.239154 (rank : 295)	θ value	3.19293e-05 (rank : 205)
Query Neighborhood Hits	1041	Target Neighborhood Hits	412	Shared Neighborhood Hits	201
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

GRASP_MOUSE
NC score	0.236038 (rank : 296)	θ value	4.1701e-05 (rank : 208)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

SH3K1_HUMAN
NC score	0.235159 (rank : 297)	θ value	9.92553e-07 (rank : 147)
Query Neighborhood Hits	1041	Target Neighborhood Hits	341	Shared Neighborhood Hits	161
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

WHRN_HUMAN
NC score	0.234940 (rank : 298)	θ value	9.29e-05 (rank : 225)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	175
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

PSCBP_MOUSE
NC score	0.231640 (rank : 299)	θ value	6.43352e-06 (rank : 174)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	98
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

USH1C_HUMAN
NC score	0.230683 (rank : 300)	θ value	0.00020696 (rank : 238)
Query Neighborhood Hits	1041	Target Neighborhood Hits	327	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

PDZD7_HUMAN
NC score	0.229874 (rank : 301)	θ value	0.00509761 (rank : 347)
Query Neighborhood Hits	1041	Target Neighborhood Hits	181	Shared Neighborhood Hits	137
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

SH3K1_MOUSE
NC score	0.229133 (rank : 302)	θ value	2.88788e-06 (rank : 161)
Query Neighborhood Hits	1041	Target Neighborhood Hits	332	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

PSCBP_HUMAN
NC score	0.226219 (rank : 303)	θ value	5.44631e-05 (rank : 214)
Query Neighborhood Hits	1041	Target Neighborhood Hits	123	Shared Neighborhood Hits	101
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

ANKR9_HUMAN
NC score	0.222127 (rank : 304)	θ value	3.0926 (rank : 780)
Query Neighborhood Hits	1041	Target Neighborhood Hits	99	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

MAGI1_HUMAN
NC score	0.220553 (rank : 305)	θ value	2.88788e-06 (rank : 159)
Query Neighborhood Hits	1041	Target Neighborhood Hits	388	Shared Neighborhood Hits	168
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.219758 (rank : 306)	θ value	4.1701e-05 (rank : 210)
Query Neighborhood Hits	1041	Target Neighborhood Hits	403	Shared Neighborhood Hits	165
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
NC score	0.217296 (rank : 307)	θ value	3.19293e-05 (rank : 202)
Query Neighborhood Hits	1041	Target Neighborhood Hits	373	Shared Neighborhood Hits	182
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

CD2AP_MOUSE
NC score	0.216179 (rank : 308)	θ value	0.00298849 (rank : 323)
Query Neighborhood Hits	1041	Target Neighborhood Hits	336	Shared Neighborhood Hits	173
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

BAT4_MOUSE
NC score	0.215418 (rank : 309)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	120
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

ARHG6_MOUSE
NC score	0.214893 (rank : 310)	θ value	2.61198e-07 (rank : 130)
Query Neighborhood Hits	1041	Target Neighborhood Hits	394	Shared Neighborhood Hits	156
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG6_HUMAN
NC score	0.212920 (rank : 311)	θ value	1.99992e-07 (rank : 124)
Query Neighborhood Hits	1041	Target Neighborhood Hits	376	Shared Neighborhood Hits	150
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

LIN7A_MOUSE
NC score	0.212559 (rank : 312)	θ value	0.00228821 (rank : 316)
Query Neighborhood Hits	1041	Target Neighborhood Hits	193	Shared Neighborhood Hits	138
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

ARHG7_MOUSE
NC score	0.211529 (rank : 313)	θ value	2.61198e-07 (rank : 131)
Query Neighborhood Hits	1041	Target Neighborhood Hits	396	Shared Neighborhood Hits	161
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

PDZD2_HUMAN
NC score	0.211437 (rank : 314)	θ value	0.000158464 (rank : 233)
Query Neighborhood Hits	1041	Target Neighborhood Hits	772	Shared Neighborhood Hits	261
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

GOPC_HUMAN
NC score	0.211366 (rank : 315)	θ value	0.000461057 (rank : 264)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

MAGI2_MOUSE
NC score	0.211251 (rank : 316)	θ value	3.19293e-05 (rank : 203)
Query Neighborhood Hits	1041	Target Neighborhood Hits	370	Shared Neighborhood Hits	173
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

LIN7B_HUMAN
NC score	0.211168 (rank : 317)	θ value	0.00390308 (rank : 334)
Query Neighborhood Hits	1041	Target Neighborhood Hits	200	Shared Neighborhood Hits	137
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

ARHG7_HUMAN
NC score	0.211023 (rank : 318)	θ value	6.87365e-08 (rank : 115)
Query Neighborhood Hits	1041	Target Neighborhood Hits	347	Shared Neighborhood Hits	158
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

LIN7A_HUMAN
NC score	0.210632 (rank : 319)	θ value	0.0113563 (rank : 372)
Query Neighborhood Hits	1041	Target Neighborhood Hits	193	Shared Neighborhood Hits	138
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

CD2AP_HUMAN
NC score	0.210399 (rank : 320)	θ value	0.0113563 (rank : 366)
Query Neighborhood Hits	1041	Target Neighborhood Hits	315	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

LIN7B_MOUSE
NC score	0.210102 (rank : 321)	θ value	0.00390308 (rank : 335)
Query Neighborhood Hits	1041	Target Neighborhood Hits	200	Shared Neighborhood Hits	137
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

ARHGB_HUMAN
NC score	0.210022 (rank : 322)	θ value	1.87187e-05 (rank : 193)
Query Neighborhood Hits	1041	Target Neighborhood Hits	375	Shared Neighborhood Hits	186
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ABTB1_HUMAN
NC score	0.209006 (rank : 323)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	158
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

GOPC_MOUSE
NC score	0.208039 (rank : 324)	θ value	0.000461057 (rank : 265)
Query Neighborhood Hits	1041	Target Neighborhood Hits	323	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LIN7C_HUMAN
NC score	0.207669 (rank : 325)	θ value	0.0113563 (rank : 373)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.207669 (rank : 326)	θ value	0.0113563 (rank : 374)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	137
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

ARHGC_HUMAN
NC score	0.207374 (rank : 327)	θ value	1.99992e-07 (rank : 125)
Query Neighborhood Hits	1041	Target Neighborhood Hits	351	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.207229 (rank : 328)	θ value	1.99992e-07 (rank : 126)
Query Neighborhood Hits	1041	Target Neighborhood Hits	344	Shared Neighborhood Hits	164
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

INADL_MOUSE
NC score	0.200664 (rank : 329)	θ value	0.00134147 (rank : 296)
Query Neighborhood Hits	1041	Target Neighborhood Hits	290	Shared Neighborhood Hits	153
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

NCK1_HUMAN
NC score	0.197460 (rank : 330)	θ value	3.77169e-06 (rank : 164)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	147
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

INADL_HUMAN
NC score	0.197289 (rank : 331)	θ value	0.00228821 (rank : 315)
Query Neighborhood Hits	1041	Target Neighborhood Hits	260	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

TX1B3_HUMAN
NC score	0.196206 (rank : 332)	θ value	0.0961366 (rank : 475)
Query Neighborhood Hits	1041	Target Neighborhood Hits	161	Shared Neighborhood Hits	123
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TRPV3_MOUSE
NC score	0.195624 (rank : 333)	θ value	θ > 10 (rank : 1457)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

NCK2_HUMAN
NC score	0.194729 (rank : 334)	θ value	2.88788e-06 (rank : 160)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	134
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

TX1B3_MOUSE
NC score	0.194443 (rank : 335)	θ value	0.0961366 (rank : 476)
Query Neighborhood Hits	1041	Target Neighborhood Hits	158	Shared Neighborhood Hits	120
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

MPDZ_MOUSE
NC score	0.194368 (rank : 336)	θ value	0.0563607 (rank : 437)
Query Neighborhood Hits	1041	Target Neighborhood Hits	298	Shared Neighborhood Hits	156
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPDZ_HUMAN
NC score	0.193578 (rank : 337)	θ value	0.0431538 (rank : 422)
Query Neighborhood Hits	1041	Target Neighborhood Hits	261	Shared Neighborhood Hits	149
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NCF1_HUMAN
NC score	0.193564 (rank : 338)	θ value	0.00035302 (rank : 255)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	126
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

TRPV3_HUMAN
NC score	0.193523 (rank : 339)	θ value	θ > 10 (rank : 1456)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	132
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV1_MOUSE
NC score	0.192734 (rank : 340)	θ value	θ > 10 (rank : 1453)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	143
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

BAT4_HUMAN
NC score	0.192465 (rank : 341)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	1041	Target Neighborhood Hits	157	Shared Neighborhood Hits	107
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

VAV_MOUSE
NC score	0.192319 (rank : 342)	θ value	8.40245e-06 (rank : 180)
Query Neighborhood Hits	1041	Target Neighborhood Hits	430	Shared Neighborhood Hits	152
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VAV_HUMAN
NC score	0.190364 (rank : 343)	θ value	1.43324e-05 (rank : 190)
Query Neighborhood Hits	1041	Target Neighborhood Hits	452	Shared Neighborhood Hits	149
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

SYP2L_HUMAN
NC score	0.189159 (rank : 344)	θ value	0.0736092 (rank : 466)
Query Neighborhood Hits	1041	Target Neighborhood Hits	400	Shared Neighborhood Hits	222
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

RSNL2_HUMAN
NC score	0.188711 (rank : 345)	θ value	θ > 10 (rank : 1362)
Query Neighborhood Hits	1041	Target Neighborhood Hits	136	Shared Neighborhood Hits	111
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ABI2_HUMAN
NC score	0.187944 (rank : 346)	θ value	0.0431538 (rank : 415)
Query Neighborhood Hits	1041	Target Neighborhood Hits	350	Shared Neighborhood Hits	206
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

NCF1_MOUSE
NC score	0.186960 (rank : 347)	θ value	0.00175202 (rank : 307)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	121
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

DNMBP_MOUSE
NC score	0.183445 (rank : 348)	θ value	0.00869519 (rank : 356)
Query Neighborhood Hits	1041	Target Neighborhood Hits	435	Shared Neighborhood Hits	177
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

VAV2_HUMAN
NC score	0.183380 (rank : 349)	θ value	2.44474e-05 (rank : 200)
Query Neighborhood Hits	1041	Target Neighborhood Hits	453	Shared Neighborhood Hits	150
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

APBA3_HUMAN
NC score	0.183258 (rank : 350)	θ value	0.00134147 (rank : 293)
Query Neighborhood Hits	1041	Target Neighborhood Hits	201	Shared Neighborhood Hits	133
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

VAV3_HUMAN
NC score	0.183115 (rank : 351)	θ value	2.88788e-06 (rank : 162)
Query Neighborhood Hits	1041	Target Neighborhood Hits	398	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

GRIP2_HUMAN
NC score	0.182872 (rank : 352)	θ value	0.0736092 (rank : 449)
Query Neighborhood Hits	1041	Target Neighborhood Hits	256	Shared Neighborhood Hits	149
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

DNMBP_HUMAN
NC score	0.182638 (rank : 353)	θ value	0.00134147 (rank : 294)
Query Neighborhood Hits	1041	Target Neighborhood Hits	413	Shared Neighborhood Hits	170
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

VAV3_MOUSE
NC score	0.182125 (rank : 354)	θ value	4.92598e-06 (rank : 170)
Query Neighborhood Hits	1041	Target Neighborhood Hits	404	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

TRPV1_HUMAN
NC score	0.181694 (rank : 355)	θ value	θ > 10 (rank : 1452)
Query Neighborhood Hits	1041	Target Neighborhood Hits	184	Shared Neighborhood Hits	137
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

VAV2_MOUSE
NC score	0.181305 (rank : 356)	θ value	5.44631e-05 (rank : 215)
Query Neighborhood Hits	1041	Target Neighborhood Hits	456	Shared Neighborhood Hits	153
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

PDZ11_HUMAN
NC score	0.180601 (rank : 357)	θ value	0.813845 (rank : 625)
Query Neighborhood Hits	1041	Target Neighborhood Hits	160	Shared Neighborhood Hits	115
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

GRAP_MOUSE
NC score	0.179879 (rank : 358)	θ value	0.125558 (rank : 481)
Query Neighborhood Hits	1041	Target Neighborhood Hits	309	Shared Neighborhood Hits	153
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SRC8_HUMAN
NC score	0.179365 (rank : 359)	θ value	0.00665767 (rank : 351)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	135
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

GRIP1_HUMAN
NC score	0.179341 (rank : 360)	θ value	0.125558 (rank : 482)
Query Neighborhood Hits	1041	Target Neighborhood Hits	231	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

APBA1_HUMAN
NC score	0.178512 (rank : 361)	θ value	0.00175202 (rank : 302)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	149
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

GRAP_HUMAN
NC score	0.178504 (rank : 362)	θ value	0.0431538 (rank : 420)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	155
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

HCLS1_MOUSE
NC score	0.178177 (rank : 363)	θ value	0.0563607 (rank : 434)
Query Neighborhood Hits	1041	Target Neighborhood Hits	329	Shared Neighborhood Hits	161
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

APBA3_MOUSE
NC score	0.177637 (rank : 364)	θ value	0.00665767 (rank : 348)
Query Neighborhood Hits	1041	Target Neighborhood Hits	174	Shared Neighborhood Hits	125
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

GRB2_HUMAN
NC score	0.176583 (rank : 365)	θ value	0.365318 (rank : 538)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	148
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.176501 (rank : 366)	θ value	0.365318 (rank : 539)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	148
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HCLS1_HUMAN
NC score	0.176344 (rank : 367)	θ value	0.279714 (rank : 523)
Query Neighborhood Hits	1041	Target Neighborhood Hits	358	Shared Neighborhood Hits	171
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

GRIP1_MOUSE
NC score	0.176341 (rank : 368)	θ value	0.125558 (rank : 483)
Query Neighborhood Hits	1041	Target Neighborhood Hits	241	Shared Neighborhood Hits	144
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SRC8_MOUSE
NC score	0.176003 (rank : 369)	θ value	0.00390308 (rank : 338)
Query Neighborhood Hits	1041	Target Neighborhood Hits	292	Shared Neighborhood Hits	140
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

PRP1_HUMAN
NC score	0.175986 (rank : 370)	θ value	θ > 10 (rank : 1333)
Query Neighborhood Hits	1041	Target Neighborhood Hits	385	Shared Neighborhood Hits	186
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SNTG1_MOUSE
NC score	0.175734 (rank : 371)	θ value	0.00228821 (rank : 319)
Query Neighborhood Hits	1041	Target Neighborhood Hits	179	Shared Neighborhood Hits	124
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
NC score	0.175380 (rank : 372)	θ value	0.00298849 (rank : 330)
Query Neighborhood Hits	1041	Target Neighborhood Hits	181	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

APBA2_HUMAN
NC score	0.175173 (rank : 373)	θ value	0.00228821 (rank : 310)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	132
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
NC score	0.173980 (rank : 374)	θ value	0.00228821 (rank : 311)
Query Neighborhood Hits	1041	Target Neighborhood Hits	219	Shared Neighborhood Hits	133
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

PARD3_HUMAN
NC score	0.173822 (rank : 375)	θ value	0.62314 (rank : 594)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

TRPV2_HUMAN
NC score	0.172981 (rank : 376)	θ value	θ > 10 (rank : 1454)
Query Neighborhood Hits	1041	Target Neighborhood Hits	130	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

STAC_MOUSE
NC score	0.172970 (rank : 377)	θ value	0.163984 (rank : 501)
Query Neighborhood Hits	1041	Target Neighborhood Hits	268	Shared Neighborhood Hits	140
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

PRP2_MOUSE
NC score	0.172346 (rank : 378)	θ value	θ > 10 (rank : 1334)
Query Neighborhood Hits	1041	Target Neighborhood Hits	347	Shared Neighborhood Hits	169
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

STAC_HUMAN
NC score	0.171958 (rank : 379)	θ value	0.0563607 (rank : 442)
Query Neighborhood Hits	1041	Target Neighborhood Hits	276	Shared Neighborhood Hits	139
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

NCF2_HUMAN
NC score	0.171335 (rank : 380)	θ value	0.0330416 (rank : 410)
Query Neighborhood Hits	1041	Target Neighborhood Hits	229	Shared Neighborhood Hits	135
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

PARD3_MOUSE
NC score	0.171121 (rank : 381)	θ value	1.06291 (rank : 652)
Query Neighborhood Hits	1041	Target Neighborhood Hits	290	Shared Neighborhood Hits	139
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

GSCR1_HUMAN
NC score	0.170819 (rank : 382)	θ value	0.00665767 (rank : 350)
Query Neighborhood Hits	1041	Target Neighborhood Hits	674	Shared Neighborhood Hits	250
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

WASIP_HUMAN
NC score	0.170585 (rank : 383)	θ value	5.27518 (rank : 912)
Query Neighborhood Hits	1041	Target Neighborhood Hits	458	Shared Neighborhood Hits	207
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SNTG2_HUMAN
NC score	0.170087 (rank : 384)	θ value	0.163984 (rank : 499)
Query Neighborhood Hits	1041	Target Neighborhood Hits	191	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PDZ11_MOUSE
NC score	0.169551 (rank : 385)	θ value	θ > 10 (rank : 1311)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	110
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PAR3L_HUMAN
NC score	0.169387 (rank : 386)	θ value	0.0736092 (rank : 458)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	135
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

ITSN2_HUMAN
NC score	0.168596 (rank : 387)	θ value	0.00134147 (rank : 298)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1173	Shared Neighborhood Hits	220
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SRBS1_MOUSE
NC score	0.168536 (rank : 388)	θ value	1.38821 (rank : 683)
Query Neighborhood Hits	1041	Target Neighborhood Hits	409	Shared Neighborhood Hits	179
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAM1_MOUSE
NC score	0.167959 (rank : 389)	θ value	0.0148317 (rank : 389)
Query Neighborhood Hits	1041	Target Neighborhood Hits	273	Shared Neighborhood Hits	159
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

WASIP_MOUSE
NC score	0.166459 (rank : 390)	θ value	1.06291 (rank : 658)
Query Neighborhood Hits	1041	Target Neighborhood Hits	392	Shared Neighborhood Hits	205
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SYJ2B_HUMAN
NC score	0.166279 (rank : 391)	θ value	θ > 10 (rank : 1423)
Query Neighborhood Hits	1041	Target Neighborhood Hits	162	Shared Neighborhood Hits	111
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

ITSN1_MOUSE
NC score	0.166191 (rank : 392)	θ value	0.000461057 (rank : 266)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1669	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_MOUSE
NC score	0.166090 (rank : 393)	θ value	0.00175202 (rank : 304)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1371	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

STAM1_HUMAN
NC score	0.166079 (rank : 394)	θ value	0.0252991 (rank : 405)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	152
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

DLG3_MOUSE
NC score	0.165651 (rank : 395)	θ value	0.813845 (rank : 613)
Query Neighborhood Hits	1041	Target Neighborhood Hits	274	Shared Neighborhood Hits	180
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.164879 (rank : 396)	θ value	0.813845 (rank : 612)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	178
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

LNX1_HUMAN
NC score	0.164795 (rank : 397)	θ value	0.000270298 (rank : 241)
Query Neighborhood Hits	1041	Target Neighborhood Hits	379	Shared Neighborhood Hits	123
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

RSNL2_MOUSE
NC score	0.164714 (rank : 398)	θ value	θ > 10 (rank : 1363)
Query Neighborhood Hits	1041	Target Neighborhood Hits	129	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ABI2_MOUSE
NC score	0.164541 (rank : 399)	θ value	0.0431538 (rank : 416)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	159
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

GRAP2_HUMAN
NC score	0.164114 (rank : 400)	θ value	1.06291 (rank : 643)
Query Neighborhood Hits	1041	Target Neighborhood Hits	304	Shared Neighborhood Hits	150
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

VINEX_HUMAN
NC score	0.163953 (rank : 401)	θ value	0.813845 (rank : 632)
Query Neighborhood Hits	1041	Target Neighborhood Hits	270	Shared Neighborhood Hits	141
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

LNX1_MOUSE
NC score	0.163899 (rank : 402)	θ value	0.0148317 (rank : 386)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	128
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

DLG2_HUMAN
NC score	0.163840 (rank : 403)	θ value	0.0736092 (rank : 448)
Query Neighborhood Hits	1041	Target Neighborhood Hits	279	Shared Neighborhood Hits	180
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

VINEX_MOUSE
NC score	0.163418 (rank : 404)	θ value	0.365318 (rank : 548)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

DLG1_HUMAN
NC score	0.163232 (rank : 405)	θ value	0.813845 (rank : 611)
Query Neighborhood Hits	1041	Target Neighborhood Hits	290	Shared Neighborhood Hits	181
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

GRAP2_MOUSE
NC score	0.162752 (rank : 406)	θ value	0.47712 (rank : 562)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	145
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

ITSN1_HUMAN
NC score	0.162295 (rank : 407)	θ value	0.00134147 (rank : 297)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1757	Shared Neighborhood Hits	288
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SRBS1_HUMAN
NC score	0.162200 (rank : 408)	θ value	1.81305 (rank : 721)
Query Neighborhood Hits	1041	Target Neighborhood Hits	396	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

DLG4_MOUSE
NC score	0.162185 (rank : 409)	θ value	0.813845 (rank : 615)
Query Neighborhood Hits	1041	Target Neighborhood Hits	282	Shared Neighborhood Hits	179
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

RHPN1_MOUSE
NC score	0.162087 (rank : 410)	θ value	0.00390308 (rank : 337)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	110
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

DLG4_HUMAN
NC score	0.161899 (rank : 411)	θ value	0.813845 (rank : 614)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	179
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PRB4S_HUMAN
NC score	0.161726 (rank : 412)	θ value	θ > 10 (rank : 1330)
Query Neighborhood Hits	1041	Target Neighborhood Hits	330	Shared Neighborhood Hits	162
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

DLG1_MOUSE
NC score	0.161154 (rank : 413)	θ value	1.06291 (rank : 641)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	176
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG2_MOUSE
NC score	0.159012 (rank : 414)	θ value	θ > 10 (rank : 1150)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	177
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

CMTA1_HUMAN
NC score	0.157691 (rank : 415)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	1041	Target Neighborhood Hits	217	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

PRR12_HUMAN
NC score	0.157400 (rank : 416)	θ value	θ > 10 (rank : 1338)
Query Neighborhood Hits	1041	Target Neighborhood Hits	460	Shared Neighborhood Hits	212
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

STAM2_MOUSE
NC score	0.157157 (rank : 417)	θ value	0.62314 (rank : 601)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	147
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SNTG2_MOUSE
NC score	0.156407 (rank : 418)	θ value	0.163984 (rank : 500)
Query Neighborhood Hits	1041	Target Neighborhood Hits	176	Shared Neighborhood Hits	122
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PRB3_HUMAN
NC score	0.155246 (rank : 419)	θ value	θ > 10 (rank : 1329)
Query Neighborhood Hits	1041	Target Neighborhood Hits	318	Shared Neighborhood Hits	161
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

STAM2_HUMAN
NC score	0.154849 (rank : 420)	θ value	0.47712 (rank : 573)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	150
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

MUC7_HUMAN
NC score	0.153681 (rank : 421)	θ value	θ > 10 (rank : 1273)
Query Neighborhood Hits	1041	Target Neighborhood Hits	538	Shared Neighborhood Hits	215
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

LNX2_HUMAN
NC score	0.153326 (rank : 422)	θ value	0.0736092 (rank : 452)
Query Neighborhood Hits	1041	Target Neighborhood Hits	389	Shared Neighborhood Hits	136
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

NACAM_MOUSE
NC score	0.153043 (rank : 423)	θ value	0.000270298 (rank : 245)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1866	Shared Neighborhood Hits	383
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CRKL_HUMAN
NC score	0.152502 (rank : 424)	θ value	0.62314 (rank : 584)
Query Neighborhood Hits	1041	Target Neighborhood Hits	313	Shared Neighborhood Hits	148
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

ABI1_HUMAN
NC score	0.152146 (rank : 425)	θ value	5.27518 (rank : 868)
Query Neighborhood Hits	1041	Target Neighborhood Hits	257	Shared Neighborhood Hits	164
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

LNX2_MOUSE
NC score	0.152135 (rank : 426)	θ value	1.38821 (rank : 674)
Query Neighborhood Hits	1041	Target Neighborhood Hits	407	Shared Neighborhood Hits	142
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

STAC3_MOUSE
NC score	0.151850 (rank : 427)	θ value	0.21417 (rank : 515)
Query Neighborhood Hits	1041	Target Neighborhood Hits	232	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CRKL_MOUSE
NC score	0.150967 (rank : 428)	θ value	0.62314 (rank : 585)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	143
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

ARHG9_MOUSE
NC score	0.150535 (rank : 429)	θ value	0.00509761 (rank : 340)
Query Neighborhood Hits	1041	Target Neighborhood Hits	234	Shared Neighborhood Hits	133
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG9_HUMAN
NC score	0.149857 (rank : 430)	θ value	0.0148317 (rank : 378)
Query Neighborhood Hits	1041	Target Neighborhood Hits	235	Shared Neighborhood Hits	134
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

CRK_MOUSE
NC score	0.149720 (rank : 431)	θ value	0.365318 (rank : 532)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	146
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

STAC3_HUMAN
NC score	0.149718 (rank : 432)	θ value	0.21417 (rank : 514)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	119
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

BAT2_HUMAN
NC score	0.149159 (rank : 433)	θ value	0.0736092 (rank : 446)
Query Neighborhood Hits	1041	Target Neighborhood Hits	931	Shared Neighborhood Hits	280
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SRRM2_HUMAN
NC score	0.149055 (rank : 434)	θ value	0.125558 (rank : 489)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1296	Shared Neighborhood Hits	304
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM1_MOUSE
NC score	0.148822 (rank : 435)	θ value	1.81305 (rank : 722)
Query Neighborhood Hits	1041	Target Neighborhood Hits	966	Shared Neighborhood Hits	257
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SH3G2_HUMAN
NC score	0.147972 (rank : 436)	θ value	0.0563607 (rank : 441)
Query Neighborhood Hits	1041	Target Neighborhood Hits	324	Shared Neighborhood Hits	137
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

PCLO_MOUSE
NC score	0.147838 (rank : 437)	θ value	0.0431538 (rank : 423)
Query Neighborhood Hits	1041	Target Neighborhood Hits	2275	Shared Neighborhood Hits	469
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SNTB2_HUMAN
NC score	0.147825 (rank : 438)	θ value	0.365318 (rank : 543)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	125
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
NC score	0.147305 (rank : 439)	θ value	0.365318 (rank : 544)
Query Neighborhood Hits	1041	Target Neighborhood Hits	181	Shared Neighborhood Hits	123
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SH3G2_MOUSE
NC score	0.146861 (rank : 440)	θ value	0.0736092 (rank : 464)
Query Neighborhood Hits	1041	Target Neighborhood Hits	319	Shared Neighborhood Hits	135
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

ABI1_MOUSE
NC score	0.146361 (rank : 441)	θ value	5.27518 (rank : 869)
Query Neighborhood Hits	1041	Target Neighborhood Hits	246	Shared Neighborhood Hits	155
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

SDCB1_MOUSE
NC score	0.146302 (rank : 442)	θ value	0.0736092 (rank : 463)
Query Neighborhood Hits	1041	Target Neighborhood Hits	144	Shared Neighborhood Hits	116
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

CRK_HUMAN
NC score	0.146051 (rank : 443)	θ value	1.81305 (rank : 694)
Query Neighborhood Hits	1041	Target Neighborhood Hits	308	Shared Neighborhood Hits	146
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

NOXO1_MOUSE
NC score	0.145956 (rank : 444)	θ value	0.0148317 (rank : 387)
Query Neighborhood Hits	1041	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

SNTA1_HUMAN
NC score	0.144730 (rank : 445)	θ value	1.81305 (rank : 716)
Query Neighborhood Hits	1041	Target Neighborhood Hits	186	Shared Neighborhood Hits	130
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

K1849_HUMAN
NC score	0.144534 (rank : 446)	θ value	0.0961366 (rank : 470)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	128
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

TAF4_HUMAN
NC score	0.143702 (rank : 447)	θ value	θ > 10 (rank : 1432)
Query Neighborhood Hits	1041	Target Neighborhood Hits	687	Shared Neighborhood Hits	216
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ARHG4_HUMAN
NC score	0.142442 (rank : 448)	θ value	8.99809 (rank : 989)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

SYP2L_MOUSE
NC score	0.142379 (rank : 449)	θ value	0.813845 (rank : 630)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	169
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

BCAR1_HUMAN
NC score	0.141535 (rank : 450)	θ value	0.00509761 (rank : 341)
Query Neighborhood Hits	1041	Target Neighborhood Hits	554	Shared Neighborhood Hits	218
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SH3G3_MOUSE
NC score	0.140768 (rank : 451)	θ value	2.36792 (rank : 765)
Query Neighborhood Hits	1041	Target Neighborhood Hits	236	Shared Neighborhood Hits	124
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

WIRE_HUMAN
NC score	0.140483 (rank : 452)	θ value	3.0926 (rank : 822)
Query Neighborhood Hits	1041	Target Neighborhood Hits	329	Shared Neighborhood Hits	168
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

PLCG1_MOUSE
NC score	0.140185 (rank : 453)	θ value	0.00298849 (rank : 329)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	123
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SNTA1_MOUSE
NC score	0.140037 (rank : 454)	θ value	3.0926 (rank : 816)
Query Neighborhood Hits	1041	Target Neighborhood Hits	170	Shared Neighborhood Hits	122
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PLCG2_HUMAN
NC score	0.139133 (rank : 455)	θ value	0.000461057 (rank : 271)
Query Neighborhood Hits	1041	Target Neighborhood Hits	280	Shared Neighborhood Hits	115
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

IL16_HUMAN
NC score	0.139116 (rank : 456)	θ value	2.36792 (rank : 746)
Query Neighborhood Hits	1041	Target Neighborhood Hits	207	Shared Neighborhood Hits	116
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LAP4_HUMAN
NC score	0.139042 (rank : 457)	θ value	1.09739e-05 (rank : 184)
Query Neighborhood Hits	1041	Target Neighborhood Hits	608	Shared Neighborhood Hits	198
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

WIRE_MOUSE
NC score	0.138760 (rank : 458)	θ value	2.36792 (rank : 775)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	160
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

SRRM2_MOUSE
NC score	0.138682 (rank : 459)	θ value	0.813845 (rank : 629)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1470	Shared Neighborhood Hits	305
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SDCB2_MOUSE
NC score	0.138259 (rank : 460)	θ value	0.0563607 (rank : 440)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	92
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

PLCG1_HUMAN
NC score	0.138016 (rank : 461)	θ value	0.00228821 (rank : 318)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	119
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SDCB1_HUMAN
NC score	0.137140 (rank : 462)	θ value	0.62314 (rank : 600)
Query Neighborhood Hits	1041	Target Neighborhood Hits	150	Shared Neighborhood Hits	120
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SRRM1_HUMAN
NC score	0.137035 (rank : 463)	θ value	θ > 10 (rank : 1420)
Query Neighborhood Hits	1041	Target Neighborhood Hits	690	Shared Neighborhood Hits	203
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

RHPN1_HUMAN
NC score	0.136952 (rank : 464)	θ value	0.0961366 (rank : 472)
Query Neighborhood Hits	1041	Target Neighborhood Hits	158	Shared Neighborhood Hits	109
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SH3G1_HUMAN
NC score	0.136418 (rank : 465)	θ value	5.27518 (rank : 903)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	136
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

NEB1_HUMAN
NC score	0.136330 (rank : 466)	θ value	θ > 10 (rank : 1279)
Query Neighborhood Hits	1041	Target Neighborhood Hits	829	Shared Neighborhood Hits	174
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PZRN3_MOUSE
NC score	0.135916 (rank : 467)	θ value	0.0113563 (rank : 375)
Query Neighborhood Hits	1041	Target Neighborhood Hits	447	Shared Neighborhood Hits	138
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

MBD6_HUMAN
NC score	0.135465 (rank : 468)	θ value	θ > 10 (rank : 1252)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	167
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PPIP1_MOUSE
NC score	0.135434 (rank : 469)	θ value	θ > 10 (rank : 1327)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	147
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

ABI3_HUMAN
NC score	0.135157 (rank : 470)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	144
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

K1849_MOUSE
NC score	0.135005 (rank : 471)	θ value	0.47712 (rank : 565)
Query Neighborhood Hits	1041	Target Neighborhood Hits	335	Shared Neighborhood Hits	150
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MUC1_HUMAN
NC score	0.134912 (rank : 472)	θ value	1.86321e-21 (rank : 4)
Query Neighborhood Hits	1041	Target Neighborhood Hits	975	Shared Neighborhood Hits	222
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SH3G1_MOUSE
NC score	0.134450 (rank : 473)	θ value	8.99809 (rank : 1031)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	137
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

BCAR1_MOUSE
NC score	0.134154 (rank : 474)	θ value	6.88961 (rank : 924)
Query Neighborhood Hits	1041	Target Neighborhood Hits	438	Shared Neighborhood Hits	195
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

RPGF6_HUMAN
NC score	0.134014 (rank : 475)	θ value	0.0252991 (rank : 401)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

LAP4_MOUSE
NC score	0.133958 (rank : 476)	θ value	5.44631e-05 (rank : 212)
Query Neighborhood Hits	1041	Target Neighborhood Hits	590	Shared Neighborhood Hits	191
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MPP4_HUMAN
NC score	0.133916 (rank : 477)	θ value	0.00509761 (rank : 345)
Query Neighborhood Hits	1041	Target Neighborhood Hits	205	Shared Neighborhood Hits	147
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PPIP1_HUMAN
NC score	0.132872 (rank : 478)	θ value	θ > 10 (rank : 1326)
Query Neighborhood Hits	1041	Target Neighborhood Hits	389	Shared Neighborhood Hits	143
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SH3G3_HUMAN
NC score	0.132699 (rank : 479)	θ value	6.88961 (rank : 971)
Query Neighborhood Hits	1041	Target Neighborhood Hits	222	Shared Neighborhood Hits	121
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

CMTA2_HUMAN
NC score	0.132660 (rank : 480)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	1041	Target Neighborhood Hits	199	Shared Neighborhood Hits	120
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

PZRN3_HUMAN
NC score	0.132592 (rank : 481)	θ value	0.0193708 (rank : 396)
Query Neighborhood Hits	1041	Target Neighborhood Hits	461	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SDCB2_HUMAN
NC score	0.132345 (rank : 482)	θ value	0.0961366 (rank : 473)
Query Neighborhood Hits	1041	Target Neighborhood Hits	121	Shared Neighborhood Hits	99
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

MDC1_HUMAN
NC score	0.132300 (rank : 483)	θ value	0.000270298 (rank : 243)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1446	Shared Neighborhood Hits	277
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NEB2_HUMAN
NC score	0.132187 (rank : 484)	θ value	0.00869519 (rank : 359)
Query Neighborhood Hits	1041	Target Neighborhood Hits	883	Shared Neighborhood Hits	173
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

IL16_MOUSE
NC score	0.131564 (rank : 485)	θ value	4.03905 (rank : 843)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	115
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SAM14_HUMAN
NC score	0.131509 (rank : 486)	θ value	0.00869519 (rank : 363)
Query Neighborhood Hits	1041	Target Neighborhood Hits	81	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

ATN1_HUMAN
NC score	0.131423 (rank : 487)	θ value	1.38821 (rank : 663)
Query Neighborhood Hits	1041	Target Neighborhood Hits	676	Shared Neighborhood Hits	228
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ABI3_MOUSE
NC score	0.131402 (rank : 488)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	150
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

EFS_HUMAN
NC score	0.131329 (rank : 489)	θ value	0.163984 (rank : 495)
Query Neighborhood Hits	1041	Target Neighborhood Hits	348	Shared Neighborhood Hits	180
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

BSN_MOUSE
NC score	0.131048 (rank : 490)	θ value	1.38821 (rank : 665)
Query Neighborhood Hits	1041	Target Neighborhood Hits	2057	Shared Neighborhood Hits	400
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PRG4_HUMAN
NC score	0.130956 (rank : 491)	θ value	θ > 10 (rank : 1331)
Query Neighborhood Hits	1041	Target Neighborhood Hits	764	Shared Neighborhood Hits	226
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RGS3_MOUSE
NC score	0.130741 (rank : 492)	θ value	2.44474e-05 (rank : 199)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1621	Shared Neighborhood Hits	363
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NEB2_MOUSE
NC score	0.130666 (rank : 493)	θ value	0.00869519 (rank : 360)
Query Neighborhood Hits	1041	Target Neighborhood Hits	889	Shared Neighborhood Hits	174
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PRRT3_HUMAN
NC score	0.130644 (rank : 494)	θ value	4.92598e-06 (rank : 169)
Query Neighborhood Hits	1041	Target Neighborhood Hits	998	Shared Neighborhood Hits	246
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PCLO_HUMAN
NC score	0.130386 (rank : 495)	θ value	0.00390308 (rank : 336)
Query Neighborhood Hits	1041	Target Neighborhood Hits	2046	Shared Neighborhood Hits	378
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CN032_HUMAN
NC score	0.130309 (rank : 496)	θ value	2.36792 (rank : 734)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	132
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

DLG5_HUMAN
NC score	0.130146 (rank : 497)	θ value	0.365318 (rank : 534)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1088	Shared Neighborhood Hits	240
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

OGFR_HUMAN
NC score	0.129770 (rank : 498)	θ value	0.00509761 (rank : 346)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1582	Shared Neighborhood Hits	318
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RIMB1_HUMAN
NC score	0.129556 (rank : 499)	θ value	0.000786445 (rank : 279)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1479	Shared Neighborhood Hits	291
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TRPV2_MOUSE
NC score	0.129167 (rank : 500)	θ value	θ > 10 (rank : 1455)
Query Neighborhood Hits	1041	Target Neighborhood Hits	111	Shared Neighborhood Hits	84
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

EFS_MOUSE
NC score	0.127954 (rank : 501)	θ value	θ > 10 (rank : 1171)
Query Neighborhood Hits	1041	Target Neighborhood Hits	389	Shared Neighborhood Hits	178
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ARHG4_MOUSE
NC score	0.127711 (rank : 502)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	1041	Target Neighborhood Hits	185	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CNKR2_MOUSE
NC score	0.127182 (rank : 503)	θ value	0.00509761 (rank : 344)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	84
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.127104 (rank : 504)	θ value	0.00509761 (rank : 343)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

BSN_HUMAN
NC score	0.126724 (rank : 505)	θ value	1.06291 (rank : 636)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1537	Shared Neighborhood Hits	343
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RPGF2_HUMAN
NC score	0.126386 (rank : 506)	θ value	0.0113563 (rank : 376)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

NU214_HUMAN
NC score	0.126224 (rank : 507)	θ value	0.00134147 (rank : 300)
Query Neighborhood Hits	1041	Target Neighborhood Hits	657	Shared Neighborhood Hits	164
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ZO1_MOUSE
NC score	0.126097 (rank : 508)	θ value	5.27518 (rank : 917)
Query Neighborhood Hits	1041	Target Neighborhood Hits	453	Shared Neighborhood Hits	201
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

MLL2_HUMAN
NC score	0.126057 (rank : 509)	θ value	0.47712 (rank : 568)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1788	Shared Neighborhood Hits	359
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ZO3_MOUSE
NC score	0.125808 (rank : 510)	θ value	2.36792 (rank : 779)
Query Neighborhood Hits	1041	Target Neighborhood Hits	224	Shared Neighborhood Hits	140
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

NOXO1_HUMAN
NC score	0.125745 (rank : 511)	θ value	0.00869519 (rank : 361)
Query Neighborhood Hits	1041	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

PDLI2_MOUSE
NC score	0.125357 (rank : 512)	θ value	0.21417 (rank : 511)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	111
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

CMTA2_MOUSE
NC score	0.125244 (rank : 513)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	1041	Target Neighborhood Hits	216	Shared Neighborhood Hits	119
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

AFAD_HUMAN
NC score	0.123887 (rank : 514)	θ value	5.27518 (rank : 870)
Query Neighborhood Hits	1041	Target Neighborhood Hits	689	Shared Neighborhood Hits	181
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ZO3_HUMAN
NC score	0.123800 (rank : 515)	θ value	1.06291 (rank : 660)
Query Neighborhood Hits	1041	Target Neighborhood Hits	219	Shared Neighborhood Hits	139
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

DGKD_HUMAN
NC score	0.123743 (rank : 516)	θ value	4.45536e-07 (rank : 139)
Query Neighborhood Hits	1041	Target Neighborhood Hits	231	Shared Neighborhood Hits	53
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

RIMB2_MOUSE
NC score	0.123707 (rank : 517)	θ value	0.0330416 (rank : 411)
Query Neighborhood Hits	1041	Target Neighborhood Hits	246	Shared Neighborhood Hits	94
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_HUMAN
NC score	0.123554 (rank : 518)	θ value	0.47712 (rank : 572)
Query Neighborhood Hits	1041	Target Neighborhood Hits	263	Shared Neighborhood Hits	106
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

PZRN4_HUMAN
NC score	0.123446 (rank : 519)	θ value	θ > 10 (rank : 1347)
Query Neighborhood Hits	1041	Target Neighborhood Hits	438	Shared Neighborhood Hits	135
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

BAT2_MOUSE
NC score	0.123115 (rank : 520)	θ value	0.163984 (rank : 494)
Query Neighborhood Hits	1041	Target Neighborhood Hits	947	Shared Neighborhood Hits	265
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NCOA6_HUMAN
NC score	0.122758 (rank : 521)	θ value	0.00102713 (rank : 290)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1202	Shared Neighborhood Hits	266
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ZO1_HUMAN
NC score	0.122560 (rank : 522)	θ value	θ > 10 (rank : 1486)
Query Neighborhood Hits	1041	Target Neighborhood Hits	474	Shared Neighborhood Hits	202
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SNTB1_HUMAN
NC score	0.121974 (rank : 523)	θ value	θ > 10 (rank : 1403)
Query Neighborhood Hits	1041	Target Neighborhood Hits	157	Shared Neighborhood Hits	113
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.121750 (rank : 524)	θ value	θ > 10 (rank : 1404)
Query Neighborhood Hits	1041	Target Neighborhood Hits	160	Shared Neighborhood Hits	112
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

BASP_MOUSE
NC score	0.121199 (rank : 525)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	1041	Target Neighborhood Hits	260	Shared Neighborhood Hits	94
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SAM14_MOUSE
NC score	0.120326 (rank : 526)	θ value	0.0563607 (rank : 439)
Query Neighborhood Hits	1041	Target Neighborhood Hits	91	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

PDLI2_HUMAN
NC score	0.119128 (rank : 527)	θ value	2.36792 (rank : 755)
Query Neighborhood Hits	1041	Target Neighborhood Hits	245	Shared Neighborhood Hits	113
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

APXL_HUMAN
NC score	0.118607 (rank : 528)	θ value	0.47712 (rank : 553)
Query Neighborhood Hits	1041	Target Neighborhood Hits	553	Shared Neighborhood Hits	158
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

TIAM1_HUMAN
NC score	0.118145 (rank : 529)	θ value	0.279714 (rank : 526)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	97
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ZO2_HUMAN
NC score	0.118054 (rank : 530)	θ value	0.813845 (rank : 633)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

NCF4_MOUSE
NC score	0.117275 (rank : 531)	θ value	θ > 10 (rank : 1277)
Query Neighborhood Hits	1041	Target Neighborhood Hits	177	Shared Neighborhood Hits	101
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

MPP4_MOUSE
NC score	0.117175 (rank : 532)	θ value	0.0193708 (rank : 394)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	133
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

TCGAP_HUMAN
NC score	0.116086 (rank : 533)	θ value	0.00390308 (rank : 339)
Query Neighborhood Hits	1041	Target Neighborhood Hits	872	Shared Neighborhood Hits	269
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RAPH1_HUMAN
NC score	0.115924 (rank : 534)	θ value	θ > 10 (rank : 1348)
Query Neighborhood Hits	1041	Target Neighborhood Hits	593	Shared Neighborhood Hits	222
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

NEBL_HUMAN
NC score	0.115888 (rank : 535)	θ value	0.813845 (rank : 622)
Query Neighborhood Hits	1041	Target Neighborhood Hits	457	Shared Neighborhood Hits	127
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

DBNL_MOUSE
NC score	0.115682 (rank : 536)	θ value	θ > 10 (rank : 1146)
Query Neighborhood Hits	1041	Target Neighborhood Hits	306	Shared Neighborhood Hits	127
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

CT032_HUMAN
NC score	0.115553 (rank : 537)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	1041	Target Neighborhood Hits	235	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DGKH_HUMAN
NC score	0.115060 (rank : 538)	θ value	4.92598e-06 (rank : 168)
Query Neighborhood Hits	1041	Target Neighborhood Hits	255	Shared Neighborhood Hits	59
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

CN155_HUMAN
NC score	0.114109 (rank : 539)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	1041	Target Neighborhood Hits	385	Shared Neighborhood Hits	133
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

RERE_MOUSE
NC score	0.113638 (rank : 540)	θ value	θ > 10 (rank : 1353)
Query Neighborhood Hits	1041	Target Neighborhood Hits	785	Shared Neighborhood Hits	251
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

PACN1_HUMAN
NC score	0.113458 (rank : 541)	θ value	1.38821 (rank : 678)
Query Neighborhood Hits	1041	Target Neighborhood Hits	320	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

MDC1_MOUSE
NC score	0.113289 (rank : 542)	θ value	0.21417 (rank : 509)
Query Neighborhood Hits	1041	Target Neighborhood Hits	998	Shared Neighborhood Hits	237
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SET1A_HUMAN
NC score	0.113020 (rank : 543)	θ value	θ > 10 (rank : 1372)
Query Neighborhood Hits	1041	Target Neighborhood Hits	690	Shared Neighborhood Hits	207
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ENAH_MOUSE
NC score	0.112876 (rank : 544)	θ value	θ > 10 (rank : 1176)
Query Neighborhood Hits	1041	Target Neighborhood Hits	919	Shared Neighborhood Hits	253
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PACN2_HUMAN
NC score	0.112849 (rank : 545)	θ value	θ > 10 (rank : 1290)
Query Neighborhood Hits	1041	Target Neighborhood Hits	339	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN1_MOUSE
NC score	0.112088 (rank : 546)	θ value	1.38821 (rank : 679)
Query Neighborhood Hits	1041	Target Neighborhood Hits	283	Shared Neighborhood Hits	130
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN2_MOUSE
NC score	0.111747 (rank : 547)	θ value	θ > 10 (rank : 1291)
Query Neighborhood Hits	1041	Target Neighborhood Hits	382	Shared Neighborhood Hits	148
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

CN032_MOUSE
NC score	0.111731 (rank : 548)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	1041	Target Neighborhood Hits	233	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

RGS12_HUMAN
NC score	0.111690 (rank : 549)	θ value	1.06291 (rank : 654)
Query Neighborhood Hits	1041	Target Neighborhood Hits	333	Shared Neighborhood Hits	154
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

DBNL_HUMAN
NC score	0.111633 (rank : 550)	θ value	θ > 10 (rank : 1145)
Query Neighborhood Hits	1041	Target Neighborhood Hits	244	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

ZO2_MOUSE
NC score	0.111585 (rank : 551)	θ value	6.88961 (rank : 986)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

SYNP2_MOUSE
NC score	0.111503 (rank : 552)	θ value	θ > 10 (rank : 1428)
Query Neighborhood Hits	1041	Target Neighborhood Hits	252	Shared Neighborhood Hits	141
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

NCF4_HUMAN
NC score	0.111440 (rank : 553)	θ value	θ > 10 (rank : 1276)
Query Neighborhood Hits	1041	Target Neighborhood Hits	161	Shared Neighborhood Hits	91
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCOA6_MOUSE
NC score	0.111054 (rank : 554)	θ value	2.36792 (rank : 753)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1076	Shared Neighborhood Hits	248
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RERE_HUMAN
NC score	0.110932 (rank : 555)	θ value	θ > 10 (rank : 1352)
Query Neighborhood Hits	1041	Target Neighborhood Hits	779	Shared Neighborhood Hits	250
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

EM55_HUMAN
NC score	0.109951 (rank : 556)	θ value	0.365318 (rank : 535)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	169
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

SI1L3_HUMAN
NC score	0.109886 (rank : 557)	θ value	0.000461057 (rank : 272)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	106
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

NPHP1_MOUSE
NC score	0.109322 (rank : 558)	θ value	θ > 10 (rank : 1286)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

TIAM1_MOUSE
NC score	0.109024 (rank : 559)	θ value	2.36792 (rank : 770)
Query Neighborhood Hits	1041	Target Neighborhood Hits	205	Shared Neighborhood Hits	79
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SON_HUMAN
NC score	0.109024 (rank : 560)	θ value	0.000786445 (rank : 280)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1568	Shared Neighborhood Hits	306
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NPHP1_HUMAN
NC score	0.109014 (rank : 561)	θ value	0.0736092 (rank : 455)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	112
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

SF3A2_MOUSE
NC score	0.108661 (rank : 562)	θ value	θ > 10 (rank : 1378)
Query Neighborhood Hits	1041	Target Neighborhood Hits	247	Shared Neighborhood Hits	114
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

ANKF1_HUMAN
NC score	0.108366 (rank : 563)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	1041	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

MLL3_HUMAN
NC score	0.108027 (rank : 564)	θ value	0.0252991 (rank : 400)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1644	Shared Neighborhood Hits	281
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CJ078_MOUSE
NC score	0.107960 (rank : 565)	θ value	4.03905 (rank : 829)
Query Neighborhood Hits	1041	Target Neighborhood Hits	559	Shared Neighborhood Hits	161
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

YLPM1_MOUSE
NC score	0.106972 (rank : 566)	θ value	θ > 10 (rank : 1482)
Query Neighborhood Hits	1041	Target Neighborhood Hits	505	Shared Neighborhood Hits	187
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

GGN_MOUSE
NC score	0.106917 (rank : 567)	θ value	θ > 10 (rank : 1203)
Query Neighborhood Hits	1041	Target Neighborhood Hits	311	Shared Neighborhood Hits	144
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PRG4_MOUSE
NC score	0.106615 (rank : 568)	θ value	θ > 10 (rank : 1332)
Query Neighborhood Hits	1041	Target Neighborhood Hits	624	Shared Neighborhood Hits	182
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RIMB1_MOUSE
NC score	0.105975 (rank : 569)	θ value	0.00175202 (rank : 308)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1376	Shared Neighborhood Hits	248
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MAGE1_HUMAN
NC score	0.105966 (rank : 570)	θ value	1.29631e-06 (rank : 149)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1389	Shared Neighborhood Hits	299
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ZN207_HUMAN
NC score	0.105607 (rank : 571)	θ value	8.99809 (rank : 1041)
Query Neighborhood Hits	1041	Target Neighborhood Hits	326	Shared Neighborhood Hits	98
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

LASP1_HUMAN
NC score	0.105455 (rank : 572)	θ value	θ > 10 (rank : 1225)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	121
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
NC score	0.105127 (rank : 573)	θ value	θ > 10 (rank : 1226)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	122
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MLL4_HUMAN
NC score	0.105033 (rank : 574)	θ value	2.36792 (rank : 751)
Query Neighborhood Hits	1041	Target Neighborhood Hits	722	Shared Neighborhood Hits	223
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

AHI1_HUMAN
NC score	0.104752 (rank : 575)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	1041	Target Neighborhood Hits	537	Shared Neighborhood Hits	145
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CIC_HUMAN
NC score	0.104568 (rank : 576)	θ value	0.0961366 (rank : 467)
Query Neighborhood Hits	1041	Target Neighborhood Hits	992	Shared Neighborhood Hits	269
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

EM55_MOUSE
NC score	0.104478 (rank : 577)	θ value	5.27518 (rank : 880)
Query Neighborhood Hits	1041	Target Neighborhood Hits	221	Shared Neighborhood Hits	166
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

SI1L2_HUMAN
NC score	0.103695 (rank : 578)	θ value	0.000121331 (rank : 228)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

MUC1_MOUSE
NC score	0.103381 (rank : 579)	θ value	θ > 10 (rank : 1271)
Query Neighborhood Hits	1041	Target Neighborhood Hits	388	Shared Neighborhood Hits	96
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

GGN_HUMAN
NC score	0.103306 (rank : 580)	θ value	θ > 10 (rank : 1202)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	132
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MUC2_HUMAN
NC score	0.102922 (rank : 581)	θ value	θ > 10 (rank : 1272)
Query Neighborhood Hits	1041	Target Neighborhood Hits	906	Shared Neighborhood Hits	222
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

BASP_HUMAN
NC score	0.102916 (rank : 582)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	1041	Target Neighborhood Hits	321	Shared Neighborhood Hits	102
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SF3A2_HUMAN
NC score	0.102770 (rank : 583)	θ value	θ > 10 (rank : 1377)
Query Neighborhood Hits	1041	Target Neighborhood Hits	263	Shared Neighborhood Hits	113
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

LCP2_HUMAN
NC score	0.102614 (rank : 584)	θ value	0.00175202 (rank : 305)
Query Neighborhood Hits	1041	Target Neighborhood Hits	531	Shared Neighborhood Hits	142
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

TRPV4_HUMAN
NC score	0.102562 (rank : 585)	θ value	θ > 10 (rank : 1458)
Query Neighborhood Hits	1041	Target Neighborhood Hits	150	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TCOF_MOUSE
NC score	0.102322 (rank : 586)	θ value	θ > 10 (rank : 1438)
Query Neighborhood Hits	1041	Target Neighborhood Hits	471	Shared Neighborhood Hits	137
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

PACN3_MOUSE
NC score	0.102302 (rank : 587)	θ value	θ > 10 (rank : 1293)
Query Neighborhood Hits	1041	Target Neighborhood Hits	380	Shared Neighborhood Hits	138
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

MLL3_MOUSE
NC score	0.102220 (rank : 588)	θ value	0.00228821 (rank : 317)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1399	Shared Neighborhood Hits	245
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

WBP11_HUMAN
NC score	0.102038 (rank : 589)	θ value	θ > 10 (rank : 1477)
Query Neighborhood Hits	1041	Target Neighborhood Hits	354	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

TCGAP_MOUSE
NC score	0.101944 (rank : 590)	θ value	0.00869519 (rank : 364)
Query Neighborhood Hits	1041	Target Neighborhood Hits	409	Shared Neighborhood Hits	189
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SI1L2_MOUSE
NC score	0.101717 (rank : 591)	θ value	0.000270298 (rank : 247)
Query Neighborhood Hits	1041	Target Neighborhood Hits	124	Shared Neighborhood Hits	48
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

ANM2_HUMAN
NC score	0.101416 (rank : 592)	θ value	0.0563607 (rank : 429)
Query Neighborhood Hits	1041	Target Neighborhood Hits	175	Shared Neighborhood Hits	108
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

WBP11_MOUSE
NC score	0.101400 (rank : 593)	θ value	θ > 10 (rank : 1478)
Query Neighborhood Hits	1041	Target Neighborhood Hits	362	Shared Neighborhood Hits	146
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

PACN3_HUMAN
NC score	0.101247 (rank : 594)	θ value	θ > 10 (rank : 1292)
Query Neighborhood Hits	1041	Target Neighborhood Hits	385	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

SI1L1_HUMAN
NC score	0.101111 (rank : 595)	θ value	0.00035302 (rank : 257)
Query Neighborhood Hits	1041	Target Neighborhood Hits	162	Shared Neighborhood Hits	54
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
NC score	0.100544 (rank : 596)	θ value	0.00035302 (rank : 258)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

DGKK_HUMAN
NC score	0.100391 (rank : 597)	θ value	θ > 10 (rank : 1147)
Query Neighborhood Hits	1041	Target Neighborhood Hits	378	Shared Neighborhood Hits	140
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

CPSF6_MOUSE
NC score	0.100230 (rank : 598)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	1041	Target Neighborhood Hits	356	Shared Neighborhood Hits	153
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

SYNP2_HUMAN
NC score	0.099784 (rank : 599)	θ value	θ > 10 (rank : 1427)
Query Neighborhood Hits	1041	Target Neighborhood Hits	323	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

LDB3_HUMAN
NC score	0.099334 (rank : 600)	θ value	θ > 10 (rank : 1234)
Query Neighborhood Hits	1041	Target Neighborhood Hits	497	Shared Neighborhood Hits	205
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

ARI1A_HUMAN
NC score	0.099314 (rank : 601)	θ value	0.21417 (rank : 503)
Query Neighborhood Hits	1041	Target Neighborhood Hits	787	Shared Neighborhood Hits	218
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

AHI1_MOUSE
NC score	0.099226 (rank : 602)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	1041	Target Neighborhood Hits	496	Shared Neighborhood Hits	144
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

CPSF6_HUMAN
NC score	0.098837 (rank : 603)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	1041	Target Neighborhood Hits	359	Shared Neighborhood Hits	152
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CBP_HUMAN
NC score	0.098743 (rank : 604)	θ value	1.06291 (rank : 637)
Query Neighborhood Hits	1041	Target Neighborhood Hits	941	Shared Neighborhood Hits	263
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CASL_MOUSE
NC score	0.098677 (rank : 605)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	125
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

NOLC1_HUMAN
NC score	0.098567 (rank : 606)	θ value	θ > 10 (rank : 1284)
Query Neighborhood Hits	1041	Target Neighborhood Hits	452	Shared Neighborhood Hits	118
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PREX1_HUMAN
NC score	0.098406 (rank : 607)	θ value	4.03905 (rank : 855)
Query Neighborhood Hits	1041	Target Neighborhood Hits	177	Shared Neighborhood Hits	70
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

MPP3_MOUSE
NC score	0.097996 (rank : 608)	θ value	1.81305 (rank : 709)
Query Neighborhood Hits	1041	Target Neighborhood Hits	165	Shared Neighborhood Hits	117
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

NGEF_MOUSE
NC score	0.097994 (rank : 609)	θ value	0.62314 (rank : 592)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PTN13_HUMAN
NC score	0.097958 (rank : 610)	θ value	2.36792 (rank : 757)
Query Neighborhood Hits	1041	Target Neighborhood Hits	471	Shared Neighborhood Hits	152
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

MUC13_MOUSE
NC score	0.097548 (rank : 611)	θ value	θ > 10 (rank : 1270)
Query Neighborhood Hits	1041	Target Neighborhood Hits	447	Shared Neighborhood Hits	109
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

BCL9_HUMAN
NC score	0.097505 (rank : 612)	θ value	1.38821 (rank : 664)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1008	Shared Neighborhood Hits	240
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

ARHG5_HUMAN
NC score	0.097203 (rank : 613)	θ value	0.365318 (rank : 529)
Query Neighborhood Hits	1041	Target Neighborhood Hits	172	Shared Neighborhood Hits	86
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

LDB3_MOUSE
NC score	0.096850 (rank : 614)	θ value	θ > 10 (rank : 1235)
Query Neighborhood Hits	1041	Target Neighborhood Hits	510	Shared Neighborhood Hits	220
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MPP3_HUMAN
NC score	0.096192 (rank : 615)	θ value	2.36792 (rank : 752)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	118
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

NFH_MOUSE
NC score	0.096107 (rank : 616)	θ value	1.09739e-05 (rank : 186)
Query Neighborhood Hits	1041	Target Neighborhood Hits	2247	Shared Neighborhood Hits	355
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TARA_HUMAN
NC score	0.095937 (rank : 617)	θ value	0.279714 (rank : 525)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1626	Shared Neighborhood Hits	276
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NCOR2_HUMAN
NC score	0.095766 (rank : 618)	θ value	0.0736092 (rank : 454)
Query Neighborhood Hits	1041	Target Neighborhood Hits	870	Shared Neighborhood Hits	217
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

LRRK1_MOUSE
NC score	0.095548 (rank : 619)	θ value	θ > 10 (rank : 1238)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1267	Shared Neighborhood Hits	180
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

M3K11_HUMAN
NC score	0.095434 (rank : 620)	θ value	0.00035302 (rank : 253)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1136	Shared Neighborhood Hits	230
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

RGS3_HUMAN
NC score	0.095315 (rank : 621)	θ value	0.0193708 (rank : 397)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1375	Shared Neighborhood Hits	271
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CBP_MOUSE
NC score	0.095121 (rank : 622)	θ value	0.47712 (rank : 555)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1051	Shared Neighborhood Hits	256
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EP300_HUMAN
NC score	0.094854 (rank : 623)	θ value	5.27518 (rank : 881)
Query Neighborhood Hits	1041	Target Neighborhood Hits	821	Shared Neighborhood Hits	236
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CASL_HUMAN
NC score	0.094238 (rank : 624)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	1041	Target Neighborhood Hits	259	Shared Neighborhood Hits	130
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

PTN13_MOUSE
NC score	0.094184 (rank : 625)	θ value	2.36792 (rank : 758)
Query Neighborhood Hits	1041	Target Neighborhood Hits	426	Shared Neighborhood Hits	155
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

ANM2_MOUSE
NC score	0.094154 (rank : 626)	θ value	0.125558 (rank : 477)
Query Neighborhood Hits	1041	Target Neighborhood Hits	175	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

CS016_HUMAN
NC score	0.093818 (rank : 627)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	129
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

TCOF_HUMAN
NC score	0.093405 (rank : 628)	θ value	θ > 10 (rank : 1437)
Query Neighborhood Hits	1041	Target Neighborhood Hits	543	Shared Neighborhood Hits	135
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

WASL_MOUSE
NC score	0.093389 (rank : 629)	θ value	θ > 10 (rank : 1474)
Query Neighborhood Hits	1041	Target Neighborhood Hits	339	Shared Neighborhood Hits	174
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

SFPQ_HUMAN
NC score	0.093253 (rank : 630)	θ value	6.88961 (rank : 970)
Query Neighborhood Hits	1041	Target Neighborhood Hits	986	Shared Neighborhood Hits	265
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

MPP5_HUMAN
NC score	0.093241 (rank : 631)	θ value	θ > 10 (rank : 1266)
Query Neighborhood Hits	1041	Target Neighborhood Hits	231	Shared Neighborhood Hits	143
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

BAG3_MOUSE
NC score	0.092949 (rank : 632)	θ value	0.279714 (rank : 517)
Query Neighborhood Hits	1041	Target Neighborhood Hits	513	Shared Neighborhood Hits	151
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

SYN1_HUMAN
NC score	0.092948 (rank : 633)	θ value	θ > 10 (rank : 1424)
Query Neighborhood Hits	1041	Target Neighborhood Hits	419	Shared Neighborhood Hits	194
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SON_MOUSE
NC score	0.092767 (rank : 634)	θ value	5.27518 (rank : 905)
Query Neighborhood Hits	1041	Target Neighborhood Hits	957	Shared Neighborhood Hits	205
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

GRIN1_HUMAN
NC score	0.092728 (rank : 635)	θ value	0.0431538 (rank : 421)
Query Neighborhood Hits	1041	Target Neighborhood Hits	681	Shared Neighborhood Hits	161
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MPP5_MOUSE
NC score	0.092460 (rank : 636)	θ value	θ > 10 (rank : 1267)
Query Neighborhood Hits	1041	Target Neighborhood Hits	226	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

SFPQ_MOUSE
NC score	0.092370 (rank : 637)	θ value	θ > 10 (rank : 1379)
Query Neighborhood Hits	1041	Target Neighborhood Hits	958	Shared Neighborhood Hits	247
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

BCL9_MOUSE
NC score	0.092117 (rank : 638)	θ value	5.27518 (rank : 874)
Query Neighborhood Hits	1041	Target Neighborhood Hits	770	Shared Neighborhood Hits	204
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

TARSH_HUMAN
NC score	0.092045 (rank : 639)	θ value	8.99809 (rank : 1034)
Query Neighborhood Hits	1041	Target Neighborhood Hits	768	Shared Neighborhood Hits	186
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CK024_HUMAN
NC score	0.091912 (rank : 640)	θ value	6.88961 (rank : 928)
Query Neighborhood Hits	1041	Target Neighborhood Hits	408	Shared Neighborhood Hits	125
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

LIPB2_MOUSE
NC score	0.091910 (rank : 641)	θ value	0.0736092 (rank : 451)
Query Neighborhood Hits	1041	Target Neighborhood Hits	570	Shared Neighborhood Hits	86
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

CIC_MOUSE
NC score	0.091870 (rank : 642)	θ value	0.813845 (rank : 607)
Query Neighborhood Hits	1041	Target Neighborhood Hits	742	Shared Neighborhood Hits	221
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

WASL_HUMAN
NC score	0.091502 (rank : 643)	θ value	θ > 10 (rank : 1473)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	163
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MARCS_HUMAN
NC score	0.091056 (rank : 644)	θ value	θ > 10 (rank : 1248)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	80
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

YLPM1_HUMAN
NC score	0.090750 (rank : 645)	θ value	θ > 10 (rank : 1481)
Query Neighborhood Hits	1041	Target Neighborhood Hits	670	Shared Neighborhood Hits	198
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

MUCDL_HUMAN
NC score	0.090747 (rank : 646)	θ value	0.0961366 (rank : 471)
Query Neighborhood Hits	1041	Target Neighborhood Hits	777	Shared Neighborhood Hits	195
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

TRPV4_MOUSE
NC score	0.090653 (rank : 647)	θ value	θ > 10 (rank : 1459)
Query Neighborhood Hits	1041	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

MARCS_MOUSE
NC score	0.090565 (rank : 648)	θ value	θ > 10 (rank : 1249)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	83
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

PKHG1_HUMAN
NC score	0.090337 (rank : 649)	θ value	θ > 10 (rank : 1323)
Query Neighborhood Hits	1041	Target Neighborhood Hits	174	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

T22D2_HUMAN
NC score	0.090091 (rank : 650)	θ value	θ > 10 (rank : 1429)
Query Neighborhood Hits	1041	Target Neighborhood Hits	250	Shared Neighborhood Hits	111
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

NGEF_HUMAN
NC score	0.089979 (rank : 651)	θ value	1.38821 (rank : 677)
Query Neighborhood Hits	1041	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

M3KL4_HUMAN
NC score	0.089486 (rank : 652)	θ value	0.000461057 (rank : 267)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1087	Shared Neighborhood Hits	189
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

NEBU_HUMAN
NC score	0.089350 (rank : 653)	θ value	8.99809 (rank : 1021)
Query Neighborhood Hits	1041	Target Neighborhood Hits	420	Shared Neighborhood Hits	128
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

PDLI5_HUMAN
NC score	0.089260 (rank : 654)	θ value	0.000461057 (rank : 270)
Query Neighborhood Hits	1041	Target Neighborhood Hits	322	Shared Neighborhood Hits	127
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

K1802_MOUSE
NC score	0.088972 (rank : 655)	θ value	0.000786445 (rank : 277)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1596	Shared Neighborhood Hits	279
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CU081_HUMAN
NC score	0.088220 (rank : 656)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	1041	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

PELP1_MOUSE
NC score	0.087392 (rank : 657)	θ value	4.03905 (rank : 852)
Query Neighborhood Hits	1041	Target Neighborhood Hits	709	Shared Neighborhood Hits	184
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PCQAP_HUMAN
NC score	0.087225 (rank : 658)	θ value	θ > 10 (rank : 1300)
Query Neighborhood Hits	1041	Target Neighborhood Hits	549	Shared Neighborhood Hits	153
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

FMN2_HUMAN
NC score	0.087108 (rank : 659)	θ value	4.03905 (rank : 839)
Query Neighborhood Hits	1041	Target Neighborhood Hits	484	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

ARHGF_HUMAN
NC score	0.086970 (rank : 660)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	1041	Target Neighborhood Hits	214	Shared Neighborhood Hits	116
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

CCNK_MOUSE
NC score	0.086805 (rank : 661)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	1041	Target Neighborhood Hits	350	Shared Neighborhood Hits	157
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

LIPB2_HUMAN
NC score	0.086476 (rank : 662)	θ value	0.0736092 (rank : 450)
Query Neighborhood Hits	1041	Target Neighborhood Hits	599	Shared Neighborhood Hits	75
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

PAR6G_HUMAN
NC score	0.086393 (rank : 663)	θ value	θ > 10 (rank : 1298)
Query Neighborhood Hits	1041	Target Neighborhood Hits	159	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PDLI7_HUMAN
NC score	0.086220 (rank : 664)	θ value	0.365318 (rank : 541)
Query Neighborhood Hits	1041	Target Neighborhood Hits	547	Shared Neighborhood Hits	173
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PRP5_HUMAN
NC score	0.086166 (rank : 665)	θ value	θ > 10 (rank : 1335)
Query Neighborhood Hits	1041	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

SARM1_MOUSE
NC score	0.086067 (rank : 666)	θ value	0.163984 (rank : 498)
Query Neighborhood Hits	1041	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

LIPB1_HUMAN
NC score	0.085931 (rank : 667)	θ value	0.00298849 (rank : 327)
Query Neighborhood Hits	1041	Target Neighborhood Hits	640	Shared Neighborhood Hits	75
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

ARHG1_MOUSE
NC score	0.085171 (rank : 668)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	1041	Target Neighborhood Hits	266	Shared Neighborhood Hits	88
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

M3K9_HUMAN
NC score	0.085154 (rank : 669)	θ value	0.00175202 (rank : 306)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1123	Shared Neighborhood Hits	205
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

TXND2_HUMAN
NC score	0.085068 (rank : 670)	θ value	0.365318 (rank : 547)
Query Neighborhood Hits	1041	Target Neighborhood Hits	793	Shared Neighborhood Hits	149
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WASF2_MOUSE
NC score	0.084967 (rank : 671)	θ value	θ > 10 (rank : 1469)
Query Neighborhood Hits	1041	Target Neighborhood Hits	315	Shared Neighborhood Hits	163
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

TGON2_HUMAN
NC score	0.084916 (rank : 672)	θ value	0.0148317 (rank : 390)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1037	Shared Neighborhood Hits	196
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

FYN_MOUSE
NC score	0.084541 (rank : 673)	θ value	0.000158464 (rank : 230)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1073	Shared Neighborhood Hits	182
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

STXB4_HUMAN
NC score	0.084375 (rank : 674)	θ value	θ > 10 (rank : 1421)
Query Neighborhood Hits	1041	Target Neighborhood Hits	616	Shared Neighborhood Hits	112
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

M3K10_HUMAN
NC score	0.084287 (rank : 675)	θ value	0.00102713 (rank : 288)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1071	Shared Neighborhood Hits	196
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

PICK1_HUMAN
NC score	0.084174 (rank : 676)	θ value	θ > 10 (rank : 1319)
Query Neighborhood Hits	1041	Target Neighborhood Hits	132	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

CDN1C_HUMAN
NC score	0.084156 (rank : 677)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	1041	Target Neighborhood Hits	168	Shared Neighborhood Hits	86
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

PDLI5_MOUSE
NC score	0.083972 (rank : 678)	θ value	0.0736092 (rank : 459)
Query Neighborhood Hits	1041	Target Neighborhood Hits	287	Shared Neighborhood Hits	121
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PI5PA_HUMAN
NC score	0.083919 (rank : 679)	θ value	θ > 10 (rank : 1317)
Query Neighborhood Hits	1041	Target Neighborhood Hits	749	Shared Neighborhood Hits	217
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

FYN_HUMAN
NC score	0.083812 (rank : 680)	θ value	0.000158464 (rank : 229)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1078	Shared Neighborhood Hits	186
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

MAST4_HUMAN
NC score	0.083704 (rank : 681)	θ value	0.000786445 (rank : 278)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1804	Shared Neighborhood Hits	366
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PICK1_MOUSE
NC score	0.083430 (rank : 682)	θ value	θ > 10 (rank : 1320)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	88
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

ALEX_HUMAN
NC score	0.083193 (rank : 683)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	1041	Target Neighborhood Hits	361	Shared Neighborhood Hits	137
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

RP1L1_HUMAN
NC score	0.083096 (rank : 684)	θ value	1.81305 (rank : 713)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1072	Shared Neighborhood Hits	195
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SYN1_MOUSE
NC score	0.083081 (rank : 685)	θ value	θ > 10 (rank : 1425)
Query Neighborhood Hits	1041	Target Neighborhood Hits	363	Shared Neighborhood Hits	171
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

PO121_MOUSE
NC score	0.083063 (rank : 686)	θ value	θ > 10 (rank : 1325)
Query Neighborhood Hits	1041	Target Neighborhood Hits	345	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SMR3A_HUMAN
NC score	0.082758 (rank : 687)	θ value	θ > 10 (rank : 1402)
Query Neighborhood Hits	1041	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

STXB4_MOUSE
NC score	0.082748 (rank : 688)	θ value	θ > 10 (rank : 1422)
Query Neighborhood Hits	1041	Target Neighborhood Hits	629	Shared Neighborhood Hits	115
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

K1802_HUMAN
NC score	0.082748 (rank : 689)	θ value	0.0961366 (rank : 469)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1378	Shared Neighborhood Hits	253
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

BAG3_HUMAN
NC score	0.082718 (rank : 690)	θ value	4.03905 (rank : 826)
Query Neighborhood Hits	1041	Target Neighborhood Hits	314	Shared Neighborhood Hits	104
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

FGR_HUMAN
NC score	0.082612 (rank : 691)	θ value	0.00298849 (rank : 326)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1067	Shared Neighborhood Hits	181
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

PAR6B_MOUSE
NC score	0.082540 (rank : 692)	θ value	θ > 10 (rank : 1297)
Query Neighborhood Hits	1041	Target Neighborhood Hits	128	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

LIPB1_MOUSE
NC score	0.082306 (rank : 693)	θ value	0.00298849 (rank : 328)
Query Neighborhood Hits	1041	Target Neighborhood Hits	727	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MY18A_MOUSE
NC score	0.082278 (rank : 694)	θ value	1.09739e-05 (rank : 185)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1989	Shared Neighborhood Hits	244
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ARHG3_MOUSE
NC score	0.082100 (rank : 695)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	1041	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

PAR6G_MOUSE
NC score	0.082054 (rank : 696)	θ value	θ > 10 (rank : 1299)
Query Neighborhood Hits	1041	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PELP1_HUMAN
NC score	0.082006 (rank : 697)	θ value	θ > 10 (rank : 1314)
Query Neighborhood Hits	1041	Target Neighborhood Hits	596	Shared Neighborhood Hits	152
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

ARHG3_HUMAN
NC score	0.082003 (rank : 698)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	1041	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

SC24C_HUMAN
NC score	0.081910 (rank : 699)	θ value	0.0252991 (rank : 403)
Query Neighborhood Hits	1041	Target Neighborhood Hits	662	Shared Neighborhood Hits	158
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MPP6_MOUSE
NC score	0.081883 (rank : 700)	θ value	θ > 10 (rank : 1269)
Query Neighborhood Hits	1041	Target Neighborhood Hits	187	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

ARHG1_HUMAN
NC score	0.081828 (rank : 701)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	1041	Target Neighborhood Hits	176	Shared Neighborhood Hits	56
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

PDZK4_HUMAN
NC score	0.081766 (rank : 702)	θ value	θ > 10 (rank : 1312)
Query Neighborhood Hits	1041	Target Neighborhood Hits	165	Shared Neighborhood Hits	94
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PAR6A_HUMAN
NC score	0.081708 (rank : 703)	θ value	θ > 10 (rank : 1294)
Query Neighborhood Hits	1041	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6B_HUMAN
NC score	0.081541 (rank : 704)	θ value	θ > 10 (rank : 1296)
Query Neighborhood Hits	1041	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

MPP6_HUMAN
NC score	0.081472 (rank : 705)	θ value	θ > 10 (rank : 1268)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

ARHGG_MOUSE
NC score	0.081357 (rank : 706)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	1041	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

PDZK4_MOUSE
NC score	0.081143 (rank : 707)	θ value	θ > 10 (rank : 1313)
Query Neighborhood Hits	1041	Target Neighborhood Hits	165	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

AMPH_MOUSE
NC score	0.080737 (rank : 708)	θ value	0.813845 (rank : 605)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	108
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ARHG8_MOUSE
NC score	0.080562 (rank : 709)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

YES_HUMAN
NC score	0.080452 (rank : 710)	θ value	0.0193708 (rank : 398)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1059	Shared Neighborhood Hits	185
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

SAMD9_HUMAN
NC score	0.080451 (rank : 711)	θ value	0.0252991 (rank : 402)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q5K651, Q6P080, Q75N21, Q8IVG6, Q9NXS8	Gene names	SAMD9, KIAA2004, OEF1
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 9.

K1543_MOUSE
NC score	0.080401 (rank : 712)	θ value	1.81305 (rank : 706)
Query Neighborhood Hits	1041	Target Neighborhood Hits	497	Shared Neighborhood Hits	148
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PDLI7_MOUSE
NC score	0.080372 (rank : 713)	θ value	0.0431538 (rank : 424)
Query Neighborhood Hits	1041	Target Neighborhood Hits	279	Shared Neighborhood Hits	103
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

YES_MOUSE
NC score	0.080370 (rank : 714)	θ value	0.00665767 (rank : 352)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1052	Shared Neighborhood Hits	180
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

AMPH_HUMAN
NC score	0.079873 (rank : 715)	θ value	8.99809 (rank : 987)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	135
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

FGR_MOUSE
NC score	0.079599 (rank : 716)	θ value	0.21417 (rank : 506)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1069	Shared Neighborhood Hits	185
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

PAR6A_MOUSE
NC score	0.079577 (rank : 717)	θ value	θ > 10 (rank : 1295)
Query Neighborhood Hits	1041	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

CS007_MOUSE
NC score	0.079550 (rank : 718)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	1041	Target Neighborhood Hits	464	Shared Neighborhood Hits	152
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

SARM1_HUMAN
NC score	0.079359 (rank : 719)	θ value	0.365318 (rank : 542)
Query Neighborhood Hits	1041	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

PO121_HUMAN
NC score	0.079276 (rank : 720)	θ value	θ > 10 (rank : 1324)
Query Neighborhood Hits	1041	Target Neighborhood Hits	344	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

MYO1F_HUMAN
NC score	0.079075 (rank : 721)	θ value	0.0563607 (rank : 438)
Query Neighborhood Hits	1041	Target Neighborhood Hits	275	Shared Neighborhood Hits	146
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

SYNJ1_MOUSE
NC score	0.078967 (rank : 722)	θ value	0.0736092 (rank : 465)
Query Neighborhood Hits	1041	Target Neighborhood Hits	516	Shared Neighborhood Hits	187
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PRR13_HUMAN
NC score	0.078673 (rank : 723)	θ value	θ > 10 (rank : 1339)
Query Neighborhood Hits	1041	Target Neighborhood Hits	105	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CO039_MOUSE
NC score	0.078625 (rank : 724)	θ value	0.365318 (rank : 531)
Query Neighborhood Hits	1041	Target Neighborhood Hits	445	Shared Neighborhood Hits	142
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

PDLI4_MOUSE
NC score	0.078490 (rank : 725)	θ value	θ > 10 (rank : 1310)
Query Neighborhood Hits	1041	Target Neighborhood Hits	233	Shared Neighborhood Hits	99
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

MYO1E_HUMAN
NC score	0.078392 (rank : 726)	θ value	0.0736092 (rank : 453)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	138
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

SAPS1_HUMAN
NC score	0.078339 (rank : 727)	θ value	0.0736092 (rank : 462)
Query Neighborhood Hits	1041	Target Neighborhood Hits	704	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SRC_HUMAN
NC score	0.077891 (rank : 728)	θ value	0.0431538 (rank : 425)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1058	Shared Neighborhood Hits	183
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

CO039_HUMAN
NC score	0.077856 (rank : 729)	θ value	4.03905 (rank : 831)
Query Neighborhood Hits	1041	Target Neighborhood Hits	264	Shared Neighborhood Hits	110
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CNOT3_HUMAN
NC score	0.077494 (rank : 730)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	1041	Target Neighborhood Hits	425	Shared Neighborhood Hits	139
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

PDLI1_HUMAN
NC score	0.077416 (rank : 731)	θ value	θ > 10 (rank : 1305)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	87
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

MYO1F_MOUSE
NC score	0.077388 (rank : 732)	θ value	0.00869519 (rank : 358)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	133
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

PDLI4_HUMAN
NC score	0.077233 (rank : 733)	θ value	θ > 10 (rank : 1309)
Query Neighborhood Hits	1041	Target Neighborhood Hits	245	Shared Neighborhood Hits	103
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

TRPC6_HUMAN
NC score	0.077043 (rank : 734)	θ value	θ > 10 (rank : 1450)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

LRRK1_HUMAN
NC score	0.076992 (rank : 735)	θ value	θ > 10 (rank : 1237)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1237	Shared Neighborhood Hits	159
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

PRRT3_MOUSE
NC score	0.076744 (rank : 736)	θ value	3.0926 (rank : 813)
Query Neighborhood Hits	1041	Target Neighborhood Hits	162	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BRD4_MOUSE
NC score	0.076679 (rank : 737)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	1041	Target Neighborhood Hits	845	Shared Neighborhood Hits	206
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

SYNJ1_HUMAN
NC score	0.076464 (rank : 738)	θ value	θ > 10 (rank : 1426)
Query Neighborhood Hits	1041	Target Neighborhood Hits	498	Shared Neighborhood Hits	182
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SELPL_MOUSE
NC score	0.076433 (rank : 739)	θ value	θ > 10 (rank : 1370)
Query Neighborhood Hits	1041	Target Neighborhood Hits	588	Shared Neighborhood Hits	151
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SF01_HUMAN
NC score	0.076404 (rank : 740)	θ value	θ > 10 (rank : 1375)
Query Neighborhood Hits	1041	Target Neighborhood Hits	287	Shared Neighborhood Hits	133
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

FMNL_HUMAN
NC score	0.076379 (rank : 741)	θ value	θ > 10 (rank : 1199)
Query Neighborhood Hits	1041	Target Neighborhood Hits	529	Shared Neighborhood Hits	185
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PDLI1_MOUSE
NC score	0.076306 (rank : 742)	θ value	θ > 10 (rank : 1306)
Query Neighborhood Hits	1041	Target Neighborhood Hits	213	Shared Neighborhood Hits	85
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

ABL1_MOUSE
NC score	0.076300 (rank : 743)	θ value	0.000461057 (rank : 260)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1178	Shared Neighborhood Hits	210
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ARHGG_HUMAN
NC score	0.076246 (rank : 744)	θ value	5.27518 (rank : 872)
Query Neighborhood Hits	1041	Target Neighborhood Hits	129	Shared Neighborhood Hits	54
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

MY18A_HUMAN
NC score	0.076147 (rank : 745)	θ value	0.000602161 (rank : 274)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1929	Shared Neighborhood Hits	230
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MINT_HUMAN
NC score	0.076038 (rank : 746)	θ value	5.27518 (rank : 892)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1291	Shared Neighborhood Hits	221
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RTP3_MOUSE
NC score	0.075656 (rank : 747)	θ value	0.62314 (rank : 599)
Query Neighborhood Hits	1041	Target Neighborhood Hits	374	Shared Neighborhood Hits	106
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RPB1_MOUSE
NC score	0.075620 (rank : 748)	θ value	θ > 10 (rank : 1361)
Query Neighborhood Hits	1041	Target Neighborhood Hits	363	Shared Neighborhood Hits	133
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TARA_MOUSE
NC score	0.075440 (rank : 749)	θ value	θ > 10 (rank : 1433)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1133	Shared Neighborhood Hits	194
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MINT_MOUSE
NC score	0.075411 (rank : 750)	θ value	2.36792 (rank : 750)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1514	Shared Neighborhood Hits	249
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GRIN1_MOUSE
NC score	0.075307 (rank : 751)	θ value	θ > 10 (rank : 1208)
Query Neighborhood Hits	1041	Target Neighborhood Hits	337	Shared Neighborhood Hits	109
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PEX13_HUMAN
NC score	0.075124 (rank : 752)	θ value	θ > 10 (rank : 1315)
Query Neighborhood Hits	1041	Target Neighborhood Hits	128	Shared Neighborhood Hits	82
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

ES8L3_HUMAN
NC score	0.075043 (rank : 753)	θ value	1.81305 (rank : 697)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	100
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

BAT3_MOUSE
NC score	0.074937 (rank : 754)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	1041	Target Neighborhood Hits	518	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

MPP2_MOUSE
NC score	0.074879 (rank : 755)	θ value	θ > 10 (rank : 1265)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	129
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

DOT1L_HUMAN
NC score	0.074819 (rank : 756)	θ value	θ > 10 (rank : 1161)
Query Neighborhood Hits	1041	Target Neighborhood Hits	660	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

RPB1_HUMAN
NC score	0.074636 (rank : 757)	θ value	θ > 10 (rank : 1360)
Query Neighborhood Hits	1041	Target Neighborhood Hits	362	Shared Neighborhood Hits	133
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

WASF2_HUMAN
NC score	0.074583 (rank : 758)	θ value	θ > 10 (rank : 1468)
Query Neighborhood Hits	1041	Target Neighborhood Hits	280	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

CNOT3_MOUSE
NC score	0.074575 (rank : 759)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	1041	Target Neighborhood Hits	504	Shared Neighborhood Hits	145
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ABL1_HUMAN
NC score	0.074471 (rank : 760)	θ value	0.000461057 (rank : 259)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1220	Shared Neighborhood Hits	208
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

RGNEF_MOUSE
NC score	0.074259 (rank : 761)	θ value	θ > 10 (rank : 1354)
Query Neighborhood Hits	1041	Target Neighborhood Hits	641	Shared Neighborhood Hits	94
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SELV_HUMAN
NC score	0.073938 (rank : 762)	θ value	θ > 10 (rank : 1371)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	68
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

FA47B_HUMAN
NC score	0.073691 (rank : 763)	θ value	0.00228821 (rank : 313)
Query Neighborhood Hits	1041	Target Neighborhood Hits	431	Shared Neighborhood Hits	112
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

MAP1A_HUMAN
NC score	0.073568 (rank : 764)	θ value	0.163984 (rank : 496)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1626	Shared Neighborhood Hits	227
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MPP2_HUMAN
NC score	0.073556 (rank : 765)	θ value	θ > 10 (rank : 1264)
Query Neighborhood Hits	1041	Target Neighborhood Hits	173	Shared Neighborhood Hits	125
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MUC5B_HUMAN
NC score	0.073535 (rank : 766)	θ value	8.99809 (rank : 1019)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1020	Shared Neighborhood Hits	183
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

K0310_HUMAN
NC score	0.073449 (rank : 767)	θ value	1.81305 (rank : 704)
Query Neighborhood Hits	1041	Target Neighborhood Hits	420	Shared Neighborhood Hits	129
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

PDLI3_HUMAN
NC score	0.073409 (rank : 768)	θ value	θ > 10 (rank : 1307)
Query Neighborhood Hits	1041	Target Neighborhood Hits	199	Shared Neighborhood Hits	92
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

MILK1_MOUSE
NC score	0.073356 (rank : 769)	θ value	θ > 10 (rank : 1256)
Query Neighborhood Hits	1041	Target Neighborhood Hits	788	Shared Neighborhood Hits	218
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CABIN_HUMAN
NC score	0.073142 (rank : 770)	θ value	6.88961 (rank : 925)
Query Neighborhood Hits	1041	Target Neighborhood Hits	490	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

NOS1_HUMAN
NC score	0.073109 (rank : 771)	θ value	0.62314 (rank : 593)
Query Neighborhood Hits	1041	Target Neighborhood Hits	218	Shared Neighborhood Hits	121
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SGIP1_MOUSE
NC score	0.073058 (rank : 772)	θ value	θ > 10 (rank : 1382)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

ARHG8_HUMAN
NC score	0.072999 (rank : 773)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	1041	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

MCF2L_MOUSE
NC score	0.072958 (rank : 774)	θ value	θ > 10 (rank : 1253)
Query Neighborhood Hits	1041	Target Neighborhood Hits	255	Shared Neighborhood Hits	57
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

PEX13_MOUSE
NC score	0.072861 (rank : 775)	θ value	θ > 10 (rank : 1316)
Query Neighborhood Hits	1041	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PRPC_HUMAN
NC score	0.072721 (rank : 776)	θ value	θ > 10 (rank : 1336)
Query Neighborhood Hits	1041	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

ES8L3_MOUSE
NC score	0.072562 (rank : 777)	θ value	θ > 10 (rank : 1182)
Query Neighborhood Hits	1041	Target Neighborhood Hits	168	Shared Neighborhood Hits	101
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ARI1B_HUMAN
NC score	0.072464 (rank : 778)	θ value	1.81305 (rank : 688)
Query Neighborhood Hits	1041	Target Neighborhood Hits	567	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CSF1_HUMAN
NC score	0.072182 (rank : 779)	θ value	0.279714 (rank : 520)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	82
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

WASF1_MOUSE
NC score	0.072151 (rank : 780)	θ value	θ > 10 (rank : 1467)
Query Neighborhood Hits	1041	Target Neighborhood Hits	261	Shared Neighborhood Hits	133
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

DVL2_HUMAN
NC score	0.072085 (rank : 781)	θ value	θ > 10 (rank : 1165)
Query Neighborhood Hits	1041	Target Neighborhood Hits	223	Shared Neighborhood Hits	126
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

MCF2_HUMAN
NC score	0.072054 (rank : 782)	θ value	θ > 10 (rank : 1254)
Query Neighborhood Hits	1041	Target Neighborhood Hits	166	Shared Neighborhood Hits	47
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

FGD1_HUMAN
NC score	0.072004 (rank : 783)	θ value	θ > 10 (rank : 1190)
Query Neighborhood Hits	1041	Target Neighborhood Hits	367	Shared Neighborhood Hits	132
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ECT2_MOUSE
NC score	0.071863 (rank : 784)	θ value	θ > 10 (rank : 1170)
Query Neighborhood Hits	1041	Target Neighborhood Hits	98	Shared Neighborhood Hits	34
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

WASF4_HUMAN
NC score	0.071827 (rank : 785)	θ value	θ > 10 (rank : 1472)
Query Neighborhood Hits	1041	Target Neighborhood Hits	282	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

RHG04_HUMAN
NC score	0.071806 (rank : 786)	θ value	θ > 10 (rank : 1355)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	125
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SPTA2_HUMAN
NC score	0.071747 (rank : 787)	θ value	1.81305 (rank : 720)
Query Neighborhood Hits	1041	Target Neighborhood Hits	888	Shared Neighborhood Hits	162
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ATX2L_HUMAN
NC score	0.071732 (rank : 788)	θ value	4.03905 (rank : 825)
Query Neighborhood Hits	1041	Target Neighborhood Hits	443	Shared Neighborhood Hits	149
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

FRK_HUMAN
NC score	0.071322 (rank : 789)	θ value	0.813845 (rank : 616)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1058	Shared Neighborhood Hits	177
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

MAST3_HUMAN
NC score	0.071148 (rank : 790)	θ value	9.29e-05 (rank : 223)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1128	Shared Neighborhood Hits	243
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

AFF1_HUMAN
NC score	0.070991 (rank : 791)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	1041	Target Neighborhood Hits	506	Shared Neighborhood Hits	134
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

RHG26_HUMAN
NC score	0.070975 (rank : 792)	θ value	θ > 10 (rank : 1356)
Query Neighborhood Hits	1041	Target Neighborhood Hits	281	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

PDLI3_MOUSE
NC score	0.070945 (rank : 793)	θ value	θ > 10 (rank : 1308)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	90
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

LAD1_MOUSE
NC score	0.070897 (rank : 794)	θ value	2.36792 (rank : 748)
Query Neighborhood Hits	1041	Target Neighborhood Hits	391	Shared Neighborhood Hits	89
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

BIN1_HUMAN
NC score	0.070873 (rank : 795)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	1041	Target Neighborhood Hits	335	Shared Neighborhood Hits	125
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

SRC_MOUSE
NC score	0.070734 (rank : 796)	θ value	0.365318 (rank : 546)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1033	Shared Neighborhood Hits	163
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

DIAP1_HUMAN
NC score	0.070543 (rank : 797)	θ value	θ > 10 (rank : 1148)
Query Neighborhood Hits	1041	Target Neighborhood Hits	784	Shared Neighborhood Hits	184
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

LCE1B_HUMAN
NC score	0.070435 (rank : 798)	θ value	θ > 10 (rank : 1229)
Query Neighborhood Hits	1041	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
NC score	0.070314 (rank : 799)	θ value	θ > 10 (rank : 1230)
Query Neighborhood Hits	1041	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

WASF1_HUMAN
NC score	0.070255 (rank : 800)	θ value	θ > 10 (rank : 1466)
Query Neighborhood Hits	1041	Target Neighborhood Hits	260	Shared Neighborhood Hits	137
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

CS007_HUMAN
NC score	0.070194 (rank : 801)	θ value	5.27518 (rank : 878)
Query Neighborhood Hits	1041	Target Neighborhood Hits	401	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DIDO1_HUMAN
NC score	0.070140 (rank : 802)	θ value	0.365318 (rank : 533)
Query Neighborhood Hits	1041	Target Neighborhood Hits	960	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SNPC4_HUMAN
NC score	0.070102 (rank : 803)	θ value	1.81305 (rank : 715)
Query Neighborhood Hits	1041	Target Neighborhood Hits	589	Shared Neighborhood Hits	163
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

FGD1_MOUSE
NC score	0.069941 (rank : 804)	θ value	θ > 10 (rank : 1191)
Query Neighborhood Hits	1041	Target Neighborhood Hits	387	Shared Neighborhood Hits	126
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SIPA1_HUMAN
NC score	0.069696 (rank : 805)	θ value	2.36792 (rank : 766)
Query Neighborhood Hits	1041	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SASH1_MOUSE
NC score	0.069557 (rank : 806)	θ value	θ > 10 (rank : 1368)
Query Neighborhood Hits	1041	Target Neighborhood Hits	263	Shared Neighborhood Hits	103
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SASH1_HUMAN
NC score	0.069510 (rank : 807)	θ value	θ > 10 (rank : 1367)
Query Neighborhood Hits	1041	Target Neighborhood Hits	292	Shared Neighborhood Hits	129
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

CTDP1_HUMAN
NC score	0.069497 (rank : 808)	θ value	0.62314 (rank : 588)
Query Neighborhood Hits	1041	Target Neighborhood Hits	416	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

ECT2_HUMAN
NC score	0.069474 (rank : 809)	θ value	θ > 10 (rank : 1169)
Query Neighborhood Hits	1041	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

HRX_HUMAN
NC score	0.069226 (rank : 810)	θ value	θ > 10 (rank : 1211)
Query Neighborhood Hits	1041	Target Neighborhood Hits	825	Shared Neighborhood Hits	167
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

T22D4_HUMAN
NC score	0.069206 (rank : 811)	θ value	0.0330416 (rank : 413)
Query Neighborhood Hits	1041	Target Neighborhood Hits	403	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

OGFR_MOUSE
NC score	0.069205 (rank : 812)	θ value	0.21417 (rank : 510)
Query Neighborhood Hits	1041	Target Neighborhood Hits	584	Shared Neighborhood Hits	123
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

DIAP1_MOUSE
NC score	0.069167 (rank : 813)	θ value	θ > 10 (rank : 1149)
Query Neighborhood Hits	1041	Target Neighborhood Hits	839	Shared Neighborhood Hits	164
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

RUSC1_HUMAN
NC score	0.069039 (rank : 814)	θ value	θ > 10 (rank : 1364)
Query Neighborhood Hits	1041	Target Neighborhood Hits	226	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SGIP1_HUMAN
NC score	0.068983 (rank : 815)	θ value	θ > 10 (rank : 1381)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

BIN1_MOUSE
NC score	0.068947 (rank : 816)	θ value	0.47712 (rank : 554)
Query Neighborhood Hits	1041	Target Neighborhood Hits	283	Shared Neighborhood Hits	118
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

LCP2_MOUSE
NC score	0.068679 (rank : 817)	θ value	θ > 10 (rank : 1233)
Query Neighborhood Hits	1041	Target Neighborhood Hits	177	Shared Neighborhood Hits	60
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

BTK_HUMAN
NC score	0.068574 (rank : 818)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1026	Shared Neighborhood Hits	172
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

FMN2_MOUSE
NC score	0.068529 (rank : 819)	θ value	2.36792 (rank : 741)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MADCA_HUMAN
NC score	0.068518 (rank : 820)	θ value	θ > 10 (rank : 1243)
Query Neighborhood Hits	1041	Target Neighborhood Hits	221	Shared Neighborhood Hits	94
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

CRTC1_HUMAN
NC score	0.068477 (rank : 821)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	1041	Target Neighborhood Hits	319	Shared Neighborhood Hits	136
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

DVL2_MOUSE
NC score	0.068373 (rank : 822)	θ value	θ > 10 (rank : 1166)
Query Neighborhood Hits	1041	Target Neighborhood Hits	233	Shared Neighborhood Hits	135
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

ABL2_HUMAN
NC score	0.068367 (rank : 823)	θ value	0.00298849 (rank : 320)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1045	Shared Neighborhood Hits	155
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

MAST1_HUMAN
NC score	0.068332 (rank : 824)	θ value	0.00035302 (rank : 254)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1146	Shared Neighborhood Hits	226
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

WASP_MOUSE
NC score	0.068276 (rank : 825)	θ value	θ > 10 (rank : 1476)
Query Neighborhood Hits	1041	Target Neighborhood Hits	223	Shared Neighborhood Hits	115
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

MAVS_HUMAN
NC score	0.068179 (rank : 826)	θ value	1.06291 (rank : 646)
Query Neighborhood Hits	1041	Target Neighborhood Hits	271	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

DAPP1_MOUSE
NC score	0.068030 (rank : 827)	θ value	θ > 10 (rank : 1144)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.067994 (rank : 828)	θ value	θ > 10 (rank : 1143)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

WNK2_HUMAN
NC score	0.067734 (rank : 829)	θ value	1.38821 (rank : 685)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1407	Shared Neighborhood Hits	282
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

PHLB1_HUMAN
NC score	0.067692 (rank : 830)	θ value	0.62314 (rank : 596)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1038	Shared Neighborhood Hits	173
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

BAT3_HUMAN
NC score	0.067626 (rank : 831)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	1041	Target Neighborhood Hits	490	Shared Neighborhood Hits	148
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

SFR15_HUMAN
NC score	0.067616 (rank : 832)	θ value	θ > 10 (rank : 1380)
Query Neighborhood Hits	1041	Target Neighborhood Hits	368	Shared Neighborhood Hits	117
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

HCK_MOUSE
NC score	0.067190 (rank : 833)	θ value	θ > 10 (rank : 1210)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1029	Shared Neighborhood Hits	167
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

LCE1D_HUMAN
NC score	0.067190 (rank : 834)	θ value	θ > 10 (rank : 1231)
Query Neighborhood Hits	1041	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

BTK_MOUSE
NC score	0.067082 (rank : 835)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1017	Shared Neighborhood Hits	168
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

PI5PA_MOUSE
NC score	0.066967 (rank : 836)	θ value	θ > 10 (rank : 1318)
Query Neighborhood Hits	1041	Target Neighborhood Hits	331	Shared Neighborhood Hits	141
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MILK1_HUMAN
NC score	0.066805 (rank : 837)	θ value	3.0926 (rank : 806)
Query Neighborhood Hits	1041	Target Neighborhood Hits	427	Shared Neighborhood Hits	153
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SREC2_HUMAN
NC score	0.066742 (rank : 838)	θ value	θ > 10 (rank : 1414)
Query Neighborhood Hits	1041	Target Neighborhood Hits	645	Shared Neighborhood Hits	122
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

MAST2_HUMAN
NC score	0.066717 (rank : 839)	θ value	0.000270298 (rank : 242)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1189	Shared Neighborhood Hits	227
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

ARHGA_HUMAN
NC score	0.066708 (rank : 840)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	1041	Target Neighborhood Hits	187	Shared Neighborhood Hits	46
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

HCK_HUMAN
NC score	0.066601 (rank : 841)	θ value	θ > 10 (rank : 1209)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1035	Shared Neighborhood Hits	170
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

RIMS1_HUMAN
NC score	0.066493 (rank : 842)	θ value	8.99809 (rank : 1029)
Query Neighborhood Hits	1041	Target Neighborhood Hits	437	Shared Neighborhood Hits	138
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

IWS1_HUMAN
NC score	0.066333 (rank : 843)	θ value	3.0926 (rank : 804)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1241	Shared Neighborhood Hits	163
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MAST1_MOUSE
NC score	0.066288 (rank : 844)	θ value	0.00102713 (rank : 289)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1123	Shared Neighborhood Hits	220
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

LCE1E_HUMAN
NC score	0.066110 (rank : 845)	θ value	θ > 10 (rank : 1232)
Query Neighborhood Hits	1041	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

MAST2_MOUSE
NC score	0.065647 (rank : 846)	θ value	0.000158464 (rank : 231)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1110	Shared Neighborhood Hits	218
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TCRG1_MOUSE
NC score	0.065526 (rank : 847)	θ value	θ > 10 (rank : 1440)
Query Neighborhood Hits	1041	Target Neighborhood Hits	947	Shared Neighborhood Hits	165
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

MAP4_MOUSE
NC score	0.065411 (rank : 848)	θ value	θ > 10 (rank : 1247)
Query Neighborhood Hits	1041	Target Neighborhood Hits	409	Shared Neighborhood Hits	106
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SLY_MOUSE
NC score	0.065383 (rank : 849)	θ value	θ > 10 (rank : 1396)
Query Neighborhood Hits	1041	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

BRD4_HUMAN
NC score	0.065368 (rank : 850)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	1041	Target Neighborhood Hits	851	Shared Neighborhood Hits	216
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

LBC_HUMAN
NC score	0.065327 (rank : 851)	θ value	θ > 10 (rank : 1227)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

NCOR2_MOUSE
NC score	0.065268 (rank : 852)	θ value	θ > 10 (rank : 1278)
Query Neighborhood Hits	1041	Target Neighborhood Hits	790	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

IWS1_MOUSE
NC score	0.065170 (rank : 853)	θ value	0.813845 (rank : 617)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1258	Shared Neighborhood Hits	181
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TM108_MOUSE
NC score	0.064957 (rank : 854)	θ value	θ > 10 (rank : 1443)
Query Neighborhood Hits	1041	Target Neighborhood Hits	336	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

LYN_HUMAN
NC score	0.064913 (rank : 855)	θ value	θ > 10 (rank : 1241)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1022	Shared Neighborhood Hits	161
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

CNKR1_HUMAN
NC score	0.064637 (rank : 856)	θ value	6.88961 (rank : 929)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	56
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

LYN_MOUSE
NC score	0.064575 (rank : 857)	θ value	θ > 10 (rank : 1242)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1023	Shared Neighborhood Hits	160
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

K1543_HUMAN
NC score	0.064394 (rank : 858)	θ value	8.99809 (rank : 1016)
Query Neighborhood Hits	1041	Target Neighborhood Hits	435	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

ZAN_MOUSE
NC score	0.064356 (rank : 859)	θ value	θ > 10 (rank : 1483)
Query Neighborhood Hits	1041	Target Neighborhood Hits	808	Shared Neighborhood Hits	82
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FA47A_HUMAN
NC score	0.064348 (rank : 860)	θ value	θ > 10 (rank : 1183)
Query Neighborhood Hits	1041	Target Neighborhood Hits	451	Shared Neighborhood Hits	104
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

EPN1_HUMAN
NC score	0.064338 (rank : 861)	θ value	6.88961 (rank : 936)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

DVL1_HUMAN
NC score	0.064206 (rank : 862)	θ value	θ > 10 (rank : 1163)
Query Neighborhood Hits	1041	Target Neighborhood Hits	158	Shared Neighborhood Hits	102
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

CD248_HUMAN
NC score	0.064144 (rank : 863)	θ value	0.0252991 (rank : 399)
Query Neighborhood Hits	1041	Target Neighborhood Hits	679	Shared Neighborhood Hits	131
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

BLNK_MOUSE
NC score	0.064100 (rank : 864)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

PCQAP_MOUSE
NC score	0.063855 (rank : 865)	θ value	θ > 10 (rank : 1301)
Query Neighborhood Hits	1041	Target Neighborhood Hits	506	Shared Neighborhood Hits	134
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

SNX18_MOUSE
NC score	0.063799 (rank : 866)	θ value	θ > 10 (rank : 1406)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	96
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

TMAP1_HUMAN
NC score	0.063756 (rank : 867)	θ value	θ > 10 (rank : 1444)
Query Neighborhood Hits	1041	Target Neighborhood Hits	140	Shared Neighborhood Hits	69
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

JIP2_HUMAN
NC score	0.063742 (rank : 868)	θ value	1.06291 (rank : 645)
Query Neighborhood Hits	1041	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

ELN_HUMAN
NC score	0.063673 (rank : 869)	θ value	θ > 10 (rank : 1174)
Query Neighborhood Hits	1041	Target Neighborhood Hits	85	Shared Neighborhood Hits	34
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

ZIMP7_MOUSE
NC score	0.063669 (rank : 870)	θ value	0.0431538 (rank : 427)
Query Neighborhood Hits	1041	Target Neighborhood Hits	566	Shared Neighborhood Hits	136
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

KI67_HUMAN
NC score	0.063596 (rank : 871)	θ value	θ > 10 (rank : 1222)
Query Neighborhood Hits	1041	Target Neighborhood Hits	581	Shared Neighborhood Hits	110
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

FGD4_MOUSE
NC score	0.063461 (rank : 872)	θ value	θ > 10 (rank : 1196)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

SLAP2_MOUSE
NC score	0.063455 (rank : 873)	θ value	θ > 10 (rank : 1395)
Query Neighborhood Hits	1041	Target Neighborhood Hits	136	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

TACC3_HUMAN
NC score	0.063366 (rank : 874)	θ value	0.0961366 (rank : 474)
Query Neighborhood Hits	1041	Target Neighborhood Hits	779	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

BLK_HUMAN
NC score	0.063337 (rank : 875)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	1041	Target Neighborhood Hits	994	Shared Neighborhood Hits	144
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

TAU_MOUSE
NC score	0.063254 (rank : 876)	θ value	θ > 10 (rank : 1435)
Query Neighborhood Hits	1041	Target Neighborhood Hits	502	Shared Neighborhood Hits	137
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

IRS2_HUMAN
NC score	0.063201 (rank : 877)	θ value	θ > 10 (rank : 1215)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

CO1A1_MOUSE
NC score	0.063186 (rank : 878)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	1041	Target Neighborhood Hits	457	Shared Neighborhood Hits	152
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SLAP2_HUMAN
NC score	0.063179 (rank : 879)	θ value	θ > 10 (rank : 1394)
Query Neighborhood Hits	1041	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

TCRG1_HUMAN
NC score	0.063069 (rank : 880)	θ value	θ > 10 (rank : 1439)
Query Neighborhood Hits	1041	Target Neighborhood Hits	929	Shared Neighborhood Hits	157
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

3BP1_HUMAN
NC score	0.062989 (rank : 881)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	1041	Target Neighborhood Hits	376	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

LMO7_HUMAN
NC score	0.062950 (rank : 882)	θ value	θ > 10 (rank : 1236)
Query Neighborhood Hits	1041	Target Neighborhood Hits	507	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

BLK_MOUSE
NC score	0.062878 (rank : 883)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	1041	Target Neighborhood Hits	992	Shared Neighborhood Hits	139
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

TAU_HUMAN
NC score	0.062833 (rank : 884)	θ value	θ > 10 (rank : 1434)
Query Neighborhood Hits	1041	Target Neighborhood Hits	448	Shared Neighborhood Hits	132
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ACINU_MOUSE
NC score	0.062822 (rank : 885)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	1041	Target Neighborhood Hits	712	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CEND3_HUMAN
NC score	0.062811 (rank : 886)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	1041	Target Neighborhood Hits	275	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

LCK_HUMAN
NC score	0.062804 (rank : 887)	θ value	0.813845 (rank : 619)
Query Neighborhood Hits	1041	Target Neighborhood Hits	987	Shared Neighborhood Hits	137
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

SLY_HUMAN
NC score	0.062799 (rank : 888)	θ value	5.27518 (rank : 904)
Query Neighborhood Hits	1041	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SF01_MOUSE
NC score	0.062769 (rank : 889)	θ value	θ > 10 (rank : 1376)
Query Neighborhood Hits	1041	Target Neighborhood Hits	240	Shared Neighborhood Hits	111
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

PTK6_MOUSE
NC score	0.062675 (rank : 890)	θ value	θ > 10 (rank : 1344)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1026	Shared Neighborhood Hits	161
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

JAG2_MOUSE
NC score	0.062662 (rank : 891)	θ value	θ > 10 (rank : 1221)
Query Neighborhood Hits	1041	Target Neighborhood Hits	504	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

MNT_HUMAN
NC score	0.062575 (rank : 892)	θ value	θ > 10 (rank : 1262)
Query Neighborhood Hits	1041	Target Neighborhood Hits	496	Shared Neighborhood Hits	136
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

LCK_MOUSE
NC score	0.062507 (rank : 893)	θ value	0.813845 (rank : 620)
Query Neighborhood Hits	1041	Target Neighborhood Hits	981	Shared Neighborhood Hits	134
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

CEL_HUMAN
NC score	0.062400 (rank : 894)	θ value	0.000786445 (rank : 276)
Query Neighborhood Hits	1041	Target Neighborhood Hits	896	Shared Neighborhood Hits	196
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FYB_HUMAN
NC score	0.062328 (rank : 895)	θ value	θ > 10 (rank : 1201)
Query Neighborhood Hits	1041	Target Neighborhood Hits	379	Shared Neighborhood Hits	121
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

ARHG2_HUMAN
NC score	0.062319 (rank : 896)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	1041	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

K1683_HUMAN
NC score	0.062246 (rank : 897)	θ value	0.47712 (rank : 564)
Query Neighborhood Hits	1041	Target Neighborhood Hits	240	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SNX18_HUMAN
NC score	0.062118 (rank : 898)	θ value	θ > 10 (rank : 1405)
Query Neighborhood Hits	1041	Target Neighborhood Hits	207	Shared Neighborhood Hits	100
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

TEC_HUMAN
NC score	0.062111 (rank : 899)	θ value	6.88961 (rank : 977)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1006	Shared Neighborhood Hits	149
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

DNER_MOUSE
NC score	0.061911 (rank : 900)	θ value	θ > 10 (rank : 1160)
Query Neighborhood Hits	1041	Target Neighborhood Hits	413	Shared Neighborhood Hits	28
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

TRDN_HUMAN
NC score	0.061812 (rank : 901)	θ value	θ > 10 (rank : 1446)
Query Neighborhood Hits	1041	Target Neighborhood Hits	542	Shared Neighborhood Hits	65
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

FMN1A_MOUSE
NC score	0.061780 (rank : 902)	θ value	θ > 10 (rank : 1197)
Query Neighborhood Hits	1041	Target Neighborhood Hits	423	Shared Neighborhood Hits	149
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

CK024_MOUSE
NC score	0.061757 (rank : 903)	θ value	1.38821 (rank : 666)
Query Neighborhood Hits	1041	Target Neighborhood Hits	307	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

DVL3_MOUSE
NC score	0.061752 (rank : 904)	θ value	θ > 10 (rank : 1168)
Query Neighborhood Hits	1041	Target Neighborhood Hits	198	Shared Neighborhood Hits	102
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

WASP_HUMAN
NC score	0.061618 (rank : 905)	θ value	θ > 10 (rank : 1475)
Query Neighborhood Hits	1041	Target Neighborhood Hits	195	Shared Neighborhood Hits	109
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

DNER_HUMAN
NC score	0.061515 (rank : 906)	θ value	θ > 10 (rank : 1159)
Query Neighborhood Hits	1041	Target Neighborhood Hits	460	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DVL3_HUMAN
NC score	0.061476 (rank : 907)	θ value	θ > 10 (rank : 1167)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	99
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

PRR13_MOUSE
NC score	0.061459 (rank : 908)	θ value	θ > 10 (rank : 1340)
Query Neighborhood Hits	1041	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CSK_HUMAN
NC score	0.061453 (rank : 909)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1009	Shared Neighborhood Hits	143
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

TXK_HUMAN
NC score	0.061422 (rank : 910)	θ value	θ > 10 (rank : 1460)
Query Neighborhood Hits	1041	Target Neighborhood Hits	971	Shared Neighborhood Hits	135
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

JAG2_HUMAN
NC score	0.061409 (rank : 911)	θ value	θ > 10 (rank : 1220)
Query Neighborhood Hits	1041	Target Neighborhood Hits	491	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

SRGP2_MOUSE
NC score	0.061310 (rank : 912)	θ value	θ > 10 (rank : 1418)
Query Neighborhood Hits	1041	Target Neighborhood Hits	324	Shared Neighborhood Hits	124
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SETD2_HUMAN
NC score	0.061232 (rank : 913)	θ value	θ > 10 (rank : 1374)
Query Neighborhood Hits	1041	Target Neighborhood Hits	412	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

TXK_MOUSE
NC score	0.061195 (rank : 914)	θ value	θ > 10 (rank : 1461)
Query Neighborhood Hits	1041	Target Neighborhood Hits	980	Shared Neighborhood Hits	145
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

PTK6_HUMAN
NC score	0.061128 (rank : 915)	θ value	θ > 10 (rank : 1343)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1020	Shared Neighborhood Hits	157
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

SPT5H_MOUSE
NC score	0.061127 (rank : 916)	θ value	3.0926 (rank : 819)
Query Neighborhood Hits	1041	Target Neighborhood Hits	437	Shared Neighborhood Hits	118
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SMR1_MOUSE
NC score	0.061122 (rank : 917)	θ value	θ > 10 (rank : 1401)
Query Neighborhood Hits	1041	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

PDC6I_MOUSE
NC score	0.061110 (rank : 918)	θ value	θ > 10 (rank : 1303)
Query Neighborhood Hits	1041	Target Neighborhood Hits	275	Shared Neighborhood Hits	120
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

CSK_MOUSE
NC score	0.061038 (rank : 919)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1009	Shared Neighborhood Hits	143
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

ENAH_HUMAN
NC score	0.061000 (rank : 920)	θ value	θ > 10 (rank : 1175)
Query Neighborhood Hits	1041	Target Neighborhood Hits	784	Shared Neighborhood Hits	175
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

MAP4_HUMAN
NC score	0.060980 (rank : 921)	θ value	θ > 10 (rank : 1246)
Query Neighborhood Hits	1041	Target Neighborhood Hits	428	Shared Neighborhood Hits	112
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SRGP1_HUMAN
NC score	0.060886 (rank : 922)	θ value	θ > 10 (rank : 1416)
Query Neighborhood Hits	1041	Target Neighborhood Hits	390	Shared Neighborhood Hits	127
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

JAG1_HUMAN
NC score	0.060841 (rank : 923)	θ value	θ > 10 (rank : 1218)
Query Neighborhood Hits	1041	Target Neighborhood Hits	514	Shared Neighborhood Hits	28
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

SPT5H_HUMAN
NC score	0.060832 (rank : 924)	θ value	3.0926 (rank : 818)
Query Neighborhood Hits	1041	Target Neighborhood Hits	436	Shared Neighborhood Hits	119
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

TB182_HUMAN
NC score	0.060797 (rank : 925)	θ value	θ > 10 (rank : 1436)
Query Neighborhood Hits	1041	Target Neighborhood Hits	414	Shared Neighborhood Hits	117
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

CO3A1_HUMAN
NC score	0.060575 (rank : 926)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	1041	Target Neighborhood Hits	452	Shared Neighborhood Hits	143
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

SPN90_HUMAN
NC score	0.060540 (rank : 927)	θ value	θ > 10 (rank : 1410)
Query Neighborhood Hits	1041	Target Neighborhood Hits	157	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SRGP2_HUMAN
NC score	0.060442 (rank : 928)	θ value	θ > 10 (rank : 1417)
Query Neighborhood Hits	1041	Target Neighborhood Hits	331	Shared Neighborhood Hits	123
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

ARHGA_MOUSE
NC score	0.060414 (rank : 929)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	1041	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

S23IP_MOUSE
NC score	0.060377 (rank : 930)	θ value	θ > 10 (rank : 1366)
Query Neighborhood Hits	1041	Target Neighborhood Hits	363	Shared Neighborhood Hits	121
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

JAG1_MOUSE
NC score	0.060376 (rank : 931)	θ value	θ > 10 (rank : 1219)
Query Neighborhood Hits	1041	Target Neighborhood Hits	518	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

ATX2L_MOUSE
NC score	0.060364 (rank : 932)	θ value	5.27518 (rank : 873)
Query Neighborhood Hits	1041	Target Neighborhood Hits	401	Shared Neighborhood Hits	123
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

RUSC2_MOUSE
NC score	0.060345 (rank : 933)	θ value	1.38821 (rank : 682)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	132
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CRUM2_HUMAN
NC score	0.060294 (rank : 934)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	1041	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

SHE_MOUSE
NC score	0.060270 (rank : 935)	θ value	0.813845 (rank : 628)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

TRPC3_HUMAN
NC score	0.060249 (rank : 936)	θ value	θ > 10 (rank : 1448)
Query Neighborhood Hits	1041	Target Neighborhood Hits	137	Shared Neighborhood Hits	72
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

FGD4_HUMAN
NC score	0.060192 (rank : 937)	θ value	θ > 10 (rank : 1195)
Query Neighborhood Hits	1041	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

DVL1_MOUSE
NC score	0.060140 (rank : 938)	θ value	θ > 10 (rank : 1164)
Query Neighborhood Hits	1041	Target Neighborhood Hits	146	Shared Neighborhood Hits	92
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

SIPA1_MOUSE
NC score	0.060047 (rank : 939)	θ value	θ > 10 (rank : 1391)
Query Neighborhood Hits	1041	Target Neighborhood Hits	158	Shared Neighborhood Hits	36
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

DVL1L_HUMAN
NC score	0.060005 (rank : 940)	θ value	θ > 10 (rank : 1162)
Query Neighborhood Hits	1041	Target Neighborhood Hits	146	Shared Neighborhood Hits	95
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

MEGF9_MOUSE
NC score	0.059866 (rank : 941)	θ value	6.88961 (rank : 954)
Query Neighborhood Hits	1041	Target Neighborhood Hits	896	Shared Neighborhood Hits	149
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CO1A1_HUMAN
NC score	0.059832 (rank : 942)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	1041	Target Neighborhood Hits	475	Shared Neighborhood Hits	153
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

ARHG2_MOUSE
NC score	0.059784 (rank : 943)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	37
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

AFF1_MOUSE
NC score	0.059764 (rank : 944)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	1041	Target Neighborhood Hits	351	Shared Neighborhood Hits	104
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ACK1_HUMAN
NC score	0.059719 (rank : 945)	θ value	0.0563607 (rank : 428)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1140	Shared Neighborhood Hits	214
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

SREC2_MOUSE
NC score	0.059692 (rank : 946)	θ value	θ > 10 (rank : 1415)
Query Neighborhood Hits	1041	Target Neighborhood Hits	605	Shared Neighborhood Hits	93
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FNBP2_HUMAN
NC score	0.059688 (rank : 947)	θ value	θ > 10 (rank : 1200)
Query Neighborhood Hits	1041	Target Neighborhood Hits	432	Shared Neighborhood Hits	128
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

ZN385_HUMAN
NC score	0.059684 (rank : 948)	θ value	0.47712 (rank : 577)
Query Neighborhood Hits	1041	Target Neighborhood Hits	614	Shared Neighborhood Hits	121
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SMAP1_MOUSE
NC score	0.059616 (rank : 949)	θ value	θ > 10 (rank : 1398)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

TACC2_MOUSE
NC score	0.059559 (rank : 950)	θ value	θ > 10 (rank : 1431)
Query Neighborhood Hits	1041	Target Neighborhood Hits	774	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

SLAP1_HUMAN
NC score	0.059375 (rank : 951)	θ value	θ > 10 (rank : 1392)
Query Neighborhood Hits	1041	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

CRUM1_HUMAN
NC score	0.059366 (rank : 952)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	1041	Target Neighborhood Hits	457	Shared Neighborhood Hits	24
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

RUSC1_MOUSE
NC score	0.059308 (rank : 953)	θ value	θ > 10 (rank : 1365)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

CRUM1_MOUSE
NC score	0.059238 (rank : 954)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	1041	Target Neighborhood Hits	444	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

PGCA_HUMAN
NC score	0.059174 (rank : 955)	θ value	0.0736092 (rank : 460)
Query Neighborhood Hits	1041	Target Neighborhood Hits	821	Shared Neighborhood Hits	126
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

NFRKB_MOUSE
NC score	0.059143 (rank : 956)	θ value	0.813845 (rank : 624)
Query Neighborhood Hits	1041	Target Neighborhood Hits	393	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

SMOO_HUMAN
NC score	0.059142 (rank : 957)	θ value	1.81305 (rank : 714)
Query Neighborhood Hits	1041	Target Neighborhood Hits	391	Shared Neighborhood Hits	135
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TEC_MOUSE
NC score	0.059097 (rank : 958)	θ value	θ > 10 (rank : 1441)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1006	Shared Neighborhood Hits	150
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

FMN1B_MOUSE
NC score	0.059096 (rank : 959)	θ value	θ > 10 (rank : 1198)
Query Neighborhood Hits	1041	Target Neighborhood Hits	447	Shared Neighborhood Hits	150
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FGD3_MOUSE
NC score	0.058983 (rank : 960)	θ value	θ > 10 (rank : 1194)
Query Neighborhood Hits	1041	Target Neighborhood Hits	257	Shared Neighborhood Hits	52
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

ATX2_HUMAN
NC score	0.058910 (rank : 961)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	1041	Target Neighborhood Hits	375	Shared Neighborhood Hits	122
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CO3A1_MOUSE
NC score	0.058825 (rank : 962)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	1041	Target Neighborhood Hits	466	Shared Neighborhood Hits	146
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

SLAP1_MOUSE
NC score	0.058694 (rank : 963)	θ value	θ > 10 (rank : 1393)
Query Neighborhood Hits	1041	Target Neighborhood Hits	117	Shared Neighborhood Hits	38
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SMAP1_HUMAN
NC score	0.058650 (rank : 964)	θ value	θ > 10 (rank : 1397)
Query Neighborhood Hits	1041	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CO4A5_HUMAN
NC score	0.058602 (rank : 965)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	1041	Target Neighborhood Hits	383	Shared Neighborhood Hits	129
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

WBS14_HUMAN
NC score	0.058505 (rank : 966)	θ value	θ > 10 (rank : 1479)
Query Neighborhood Hits	1041	Target Neighborhood Hits	273	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

VCX3_HUMAN
NC score	0.058380 (rank : 967)	θ value	θ > 10 (rank : 1464)
Query Neighborhood Hits	1041	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

CEND3_MOUSE
NC score	0.058368 (rank : 968)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

MNT_MOUSE
NC score	0.058368 (rank : 969)	θ value	θ > 10 (rank : 1263)
Query Neighborhood Hits	1041	Target Neighborhood Hits	432	Shared Neighborhood Hits	122
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RFIP3_HUMAN
NC score	0.058249 (rank : 970)	θ value	1.38821 (rank : 681)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1055	Shared Neighborhood Hits	149
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

COHA1_HUMAN
NC score	0.058242 (rank : 971)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	1041	Target Neighborhood Hits	400	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

SPTA1_MOUSE
NC score	0.058214 (rank : 972)	θ value	θ > 10 (rank : 1413)
Query Neighborhood Hits	1041	Target Neighborhood Hits	675	Shared Neighborhood Hits	140
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ATX2_MOUSE
NC score	0.058147 (rank : 973)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	1041	Target Neighborhood Hits	445	Shared Neighborhood Hits	133
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

TM108_HUMAN
NC score	0.058062 (rank : 974)	θ value	θ > 10 (rank : 1442)
Query Neighborhood Hits	1041	Target Neighborhood Hits	166	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ACK1_MOUSE
NC score	0.058039 (rank : 975)	θ value	2.36792 (rank : 727)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1080	Shared Neighborhood Hits	200
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

MAP1B_MOUSE
NC score	0.057904 (rank : 976)	θ value	θ > 10 (rank : 1245)
Query Neighborhood Hits	1041	Target Neighborhood Hits	977	Shared Neighborhood Hits	152
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TF65_HUMAN
NC score	0.057890 (rank : 977)	θ value	6.88961 (rank : 978)
Query Neighborhood Hits	1041	Target Neighborhood Hits	115	Shared Neighborhood Hits	40
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

SPTA1_HUMAN
NC score	0.057831 (rank : 978)	θ value	θ > 10 (rank : 1412)
Query Neighborhood Hits	1041	Target Neighborhood Hits	748	Shared Neighborhood Hits	151
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

LEUK_HUMAN
NC score	0.057739 (rank : 979)	θ value	1.38821 (rank : 673)
Query Neighborhood Hits	1041	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

RTN4_HUMAN
NC score	0.057697 (rank : 980)	θ value	5.27518 (rank : 900)
Query Neighborhood Hits	1041	Target Neighborhood Hits	357	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SHC1_HUMAN
NC score	0.057657 (rank : 981)	θ value	θ > 10 (rank : 1384)
Query Neighborhood Hits	1041	Target Neighborhood Hits	170	Shared Neighborhood Hits	59
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

WASF3_HUMAN
NC score	0.057538 (rank : 982)	θ value	θ > 10 (rank : 1470)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

EPN3_MOUSE
NC score	0.057510 (rank : 983)	θ value	0.0563607 (rank : 433)
Query Neighborhood Hits	1041	Target Neighborhood Hits	312	Shared Neighborhood Hits	94
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

MN1_HUMAN
NC score	0.057491 (rank : 984)	θ value	θ > 10 (rank : 1261)
Query Neighborhood Hits	1041	Target Neighborhood Hits	196	Shared Neighborhood Hits	85
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

RIPK2_HUMAN
NC score	0.057434 (rank : 985)	θ value	θ > 10 (rank : 1358)
Query Neighborhood Hits	1041	Target Neighborhood Hits	774	Shared Neighborhood Hits	68
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

EGFL9_HUMAN
NC score	0.057380 (rank : 986)	θ value	θ > 10 (rank : 1172)
Query Neighborhood Hits	1041	Target Neighborhood Hits	365	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

MLKL_HUMAN
NC score	0.057222 (rank : 987)	θ value	θ > 10 (rank : 1258)
Query Neighborhood Hits	1041	Target Neighborhood Hits	600	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

LTBP4_MOUSE
NC score	0.057170 (rank : 988)	θ value	θ > 10 (rank : 1240)
Query Neighborhood Hits	1041	Target Neighborhood Hits	607	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FGD3_HUMAN
NC score	0.057166 (rank : 989)	θ value	6.88961 (rank : 938)
Query Neighborhood Hits	1041	Target Neighborhood Hits	249	Shared Neighborhood Hits	61
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

EGFL9_MOUSE
NC score	0.057157 (rank : 990)	θ value	θ > 10 (rank : 1173)
Query Neighborhood Hits	1041	Target Neighborhood Hits	379	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

PDC6I_HUMAN
NC score	0.057149 (rank : 991)	θ value	θ > 10 (rank : 1302)
Query Neighborhood Hits	1041	Target Neighborhood Hits	278	Shared Neighborhood Hits	119
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

MISS_MOUSE
NC score	0.057139 (rank : 992)	θ value	θ > 10 (rank : 1257)
Query Neighborhood Hits	1041	Target Neighborhood Hits	444	Shared Neighborhood Hits	124
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PININ_MOUSE
NC score	0.057111 (rank : 993)	θ value	θ > 10 (rank : 1321)
Query Neighborhood Hits	1041	Target Neighborhood Hits	777	Shared Neighborhood Hits	124
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

AMOT_HUMAN
NC score	0.057069 (rank : 994)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	1041	Target Neighborhood Hits	712	Shared Neighborhood Hits	134
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

NOS1_MOUSE
NC score	0.057026 (rank : 995)	θ value	θ > 10 (rank : 1285)
Query Neighborhood Hits	1041	Target Neighborhood Hits	155	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

HRBL_MOUSE
NC score	0.057021 (rank : 996)	θ value	1.06291 (rank : 644)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	83
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

VCXC_HUMAN
NC score	0.056895 (rank : 997)	θ value	θ > 10 (rank : 1465)
Query Neighborhood Hits	1041	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

CENA1_HUMAN
NC score	0.056834 (rank : 998)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	1041	Target Neighborhood Hits	87	Shared Neighborhood Hits	24
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

P85B_HUMAN
NC score	0.056704 (rank : 999)	θ value	θ > 10 (rank : 1288)
Query Neighborhood Hits	1041	Target Neighborhood Hits	543	Shared Neighborhood Hits	100
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

IF4G1_MOUSE
NC score	0.056671 (rank : 1000)	θ value	0.47712 (rank : 563)
Query Neighborhood Hits	1041	Target Neighborhood Hits	534	Shared Neighborhood Hits	142
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MAP1B_HUMAN
NC score	0.056548 (rank : 1001)	θ value	θ > 10 (rank : 1244)
Query Neighborhood Hits	1041	Target Neighborhood Hits	903	Shared Neighborhood Hits	136
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SHC3_MOUSE
NC score	0.056536 (rank : 1002)	θ value	θ > 10 (rank : 1388)
Query Neighborhood Hits	1041	Target Neighborhood Hits	151	Shared Neighborhood Hits	48
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

LPP_HUMAN
NC score	0.056367 (rank : 1003)	θ value	0.125558 (rank : 486)
Query Neighborhood Hits	1041	Target Neighborhood Hits	775	Shared Neighborhood Hits	162
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

RIN3_MOUSE
NC score	0.056315 (rank : 1004)	θ value	θ > 10 (rank : 1357)
Query Neighborhood Hits	1041	Target Neighborhood Hits	239	Shared Neighborhood Hits	99
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ITK_HUMAN
NC score	0.056291 (rank : 1005)	θ value	θ > 10 (rank : 1216)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1016	Shared Neighborhood Hits	143
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

PRPE_HUMAN
NC score	0.056253 (rank : 1006)	θ value	θ > 10 (rank : 1337)
Query Neighborhood Hits	1041	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

GTSE1_HUMAN
NC score	0.056237 (rank : 1007)	θ value	3.0926 (rank : 798)
Query Neighborhood Hits	1041	Target Neighborhood Hits	193	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

PKHG4_HUMAN
NC score	0.056098 (rank : 1008)	θ value	6.88961 (rank : 960)
Query Neighborhood Hits	1041	Target Neighborhood Hits	200	Shared Neighborhood Hits	58
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

SMP1L_HUMAN
NC score	0.055981 (rank : 1009)	θ value	θ > 10 (rank : 1399)
Query Neighborhood Hits	1041	Target Neighborhood Hits	74	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

ENL_HUMAN
NC score	0.055927 (rank : 1010)	θ value	θ > 10 (rank : 1177)
Query Neighborhood Hits	1041	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

PTN23_HUMAN
NC score	0.055852 (rank : 1011)	θ value	θ > 10 (rank : 1345)
Query Neighborhood Hits	1041	Target Neighborhood Hits	646	Shared Neighborhood Hits	197
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PRR8_HUMAN
NC score	0.055796 (rank : 1012)	θ value	θ > 10 (rank : 1341)
Query Neighborhood Hits	1041	Target Neighborhood Hits	217	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

EPN1_MOUSE
NC score	0.055794 (rank : 1013)	θ value	θ > 10 (rank : 1179)
Query Neighborhood Hits	1041	Target Neighborhood Hits	240	Shared Neighborhood Hits	101
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

PSL1_HUMAN
NC score	0.055760 (rank : 1014)	θ value	0.0736092 (rank : 461)
Query Neighborhood Hits	1041	Target Neighborhood Hits	650	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SHC3_HUMAN
NC score	0.055721 (rank : 1015)	θ value	θ > 10 (rank : 1387)
Query Neighborhood Hits	1041	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SMP1L_MOUSE
NC score	0.055672 (rank : 1016)	θ value	θ > 10 (rank : 1400)
Query Neighborhood Hits	1041	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

MMRN1_HUMAN
NC score	0.055457 (rank : 1017)	θ value	θ > 10 (rank : 1260)
Query Neighborhood Hits	1041	Target Neighborhood Hits	636	Shared Neighborhood Hits	59
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

TXLNB_HUMAN
NC score	0.055442 (rank : 1018)	θ value	2.36792 (rank : 772)
Query Neighborhood Hits	1041	Target Neighborhood Hits	912	Shared Neighborhood Hits	150
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

SHC1_MOUSE
NC score	0.055368 (rank : 1019)	θ value	θ > 10 (rank : 1385)
Query Neighborhood Hits	1041	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

TACC2_HUMAN
NC score	0.055362 (rank : 1020)	θ value	θ > 10 (rank : 1430)
Query Neighborhood Hits	1041	Target Neighborhood Hits	856	Shared Neighborhood Hits	139
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

DLL3_MOUSE
NC score	0.055346 (rank : 1021)	θ value	θ > 10 (rank : 1156)
Query Neighborhood Hits	1041	Target Neighborhood Hits	399	Shared Neighborhood Hits	22
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

SETB1_MOUSE
NC score	0.055285 (rank : 1022)	θ value	θ > 10 (rank : 1373)
Query Neighborhood Hits	1041	Target Neighborhood Hits	150	Shared Neighborhood Hits	43
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

CT2NL_HUMAN
NC score	0.055264 (rank : 1023)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1059	Shared Neighborhood Hits	123
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MLTK_HUMAN
NC score	0.055237 (rank : 1024)	θ value	0.125558 (rank : 487)
Query Neighborhood Hits	1041	Target Neighborhood Hits	911	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

COGA1_HUMAN
NC score	0.055132 (rank : 1025)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	1041	Target Neighborhood Hits	345	Shared Neighborhood Hits	112
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CD248_MOUSE
NC score	0.054904 (rank : 1026)	θ value	5.27518 (rank : 875)
Query Neighborhood Hits	1041	Target Neighborhood Hits	578	Shared Neighborhood Hits	105
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FGD2_MOUSE
NC score	0.054871 (rank : 1027)	θ value	θ > 10 (rank : 1193)
Query Neighborhood Hits	1041	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

T22D4_MOUSE
NC score	0.054822 (rank : 1028)	θ value	0.0330416 (rank : 414)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	Q9EQN3	Gene names	Tsc22d4, Tilz2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2).

MLTK_MOUSE
NC score	0.054805 (rank : 1029)	θ value	0.125558 (rank : 488)
Query Neighborhood Hits	1041	Target Neighborhood Hits	874	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

PPRB_MOUSE
NC score	0.054792 (rank : 1030)	θ value	θ > 10 (rank : 1328)
Query Neighborhood Hits	1041	Target Neighborhood Hits	354	Shared Neighborhood Hits	104
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

WASF3_MOUSE
NC score	0.054779 (rank : 1031)	θ value	θ > 10 (rank : 1471)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

IF35_MOUSE
NC score	0.054773 (rank : 1032)	θ value	θ > 10 (rank : 1213)
Query Neighborhood Hits	1041	Target Neighborhood Hits	210	Shared Neighborhood Hits	99
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

TROAP_HUMAN
NC score	0.054725 (rank : 1033)	θ value	θ > 10 (rank : 1447)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	92
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TRPC3_MOUSE
NC score	0.054694 (rank : 1034)	θ value	θ > 10 (rank : 1449)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

MKL1_MOUSE
NC score	0.054657 (rank : 1035)	θ value	0.365318 (rank : 540)
Query Neighborhood Hits	1041	Target Neighborhood Hits	667	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NFH_HUMAN
NC score	0.054588 (rank : 1036)	θ value	θ > 10 (rank : 1282)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1242	Shared Neighborhood Hits	184
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LAD1_HUMAN
NC score	0.054588 (rank : 1037)	θ value	θ > 10 (rank : 1224)
Query Neighborhood Hits	1041	Target Neighborhood Hits	441	Shared Neighborhood Hits	91
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

DLL4_MOUSE
NC score	0.054548 (rank : 1038)	θ value	θ > 10 (rank : 1158)
Query Neighborhood Hits	1041	Target Neighborhood Hits	440	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

P85B_MOUSE
NC score	0.054513 (rank : 1039)	θ value	θ > 10 (rank : 1289)
Query Neighborhood Hits	1041	Target Neighborhood Hits	519	Shared Neighborhood Hits	91
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PDCD7_HUMAN
NC score	0.054368 (rank : 1040)	θ value	θ > 10 (rank : 1304)
Query Neighborhood Hits	1041	Target Neighborhood Hits	255	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

TRPC6_MOUSE
NC score	0.054360 (rank : 1041)	θ value	θ > 10 (rank : 1451)
Query Neighborhood Hits	1041	Target Neighborhood Hits	171	Shared Neighborhood Hits	84
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

ITK_MOUSE
NC score	0.054344 (rank : 1042)	θ value	θ > 10 (rank : 1217)
Query Neighborhood Hits	1041	Target Neighborhood Hits	985	Shared Neighborhood Hits	133
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

NSD1_MOUSE
NC score	0.054313 (rank : 1043)	θ value	θ > 10 (rank : 1287)
Query Neighborhood Hits	1041	Target Neighborhood Hits	472	Shared Neighborhood Hits	95
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

DLL3_HUMAN
NC score	0.054285 (rank : 1044)	θ value	θ > 10 (rank : 1155)
Query Neighborhood Hits	1041	Target Neighborhood Hits	419	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

MUCDL_MOUSE
NC score	0.054084 (rank : 1045)	θ value	θ > 10 (rank : 1274)
Query Neighborhood Hits	1041	Target Neighborhood Hits	461	Shared Neighborhood Hits	119
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

FGD2_HUMAN
NC score	0.054044 (rank : 1046)	θ value	θ > 10 (rank : 1192)
Query Neighborhood Hits	1041	Target Neighborhood Hits	151	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

SPN90_MOUSE
NC score	0.053969 (rank : 1047)	θ value	θ > 10 (rank : 1411)
Query Neighborhood Hits	1041	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

LCE1A_HUMAN
NC score	0.053937 (rank : 1048)	θ value	θ > 10 (rank : 1228)
Query Neighborhood Hits	1041	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

SHD_HUMAN
NC score	0.053833 (rank : 1049)	θ value	θ > 10 (rank : 1389)
Query Neighborhood Hits	1041	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

ES8L2_HUMAN
NC score	0.053742 (rank : 1050)	θ value	θ > 10 (rank : 1180)
Query Neighborhood Hits	1041	Target Neighborhood Hits	193	Shared Neighborhood Hits	95
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

IF4G1_HUMAN
NC score	0.053658 (rank : 1051)	θ value	θ > 10 (rank : 1214)
Query Neighborhood Hits	1041	Target Neighborhood Hits	347	Shared Neighborhood Hits	133
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

PKHA6_MOUSE
NC score	0.053647 (rank : 1052)	θ value	θ > 10 (rank : 1322)
Query Neighborhood Hits	1041	Target Neighborhood Hits	591	Shared Neighborhood Hits	125
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

VCX1_HUMAN
NC score	0.053615 (rank : 1053)	θ value	θ > 10 (rank : 1463)
Query Neighborhood Hits	1041	Target Neighborhood Hits	129	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

KR104_HUMAN
NC score	0.053314 (rank : 1054)	θ value	θ > 10 (rank : 1223)
Query Neighborhood Hits	1041	Target Neighborhood Hits	313	Shared Neighborhood Hits	20
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

ES8L2_MOUSE
NC score	0.053205 (rank : 1055)	θ value	θ > 10 (rank : 1181)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	91
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

SC24D_HUMAN
NC score	0.053171 (rank : 1056)	θ value	θ > 10 (rank : 1369)
Query Neighborhood Hits	1041	Target Neighborhood Hits	173	Shared Neighborhood Hits	79
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

CT174_HUMAN
NC score	0.053154 (rank : 1057)	θ value	2.36792 (rank : 737)
Query Neighborhood Hits	1041	Target Neighborhood Hits	181	Shared Neighborhood Hits	62
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

REL_MOUSE
NC score	0.053149 (rank : 1058)	θ value	1.06291 (rank : 653)
Query Neighborhood Hits	1041	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

DLL4_HUMAN
NC score	0.053115 (rank : 1059)	θ value	θ > 10 (rank : 1157)
Query Neighborhood Hits	1041	Target Neighborhood Hits	435	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FBN3_HUMAN
NC score	0.052970 (rank : 1060)	θ value	θ > 10 (rank : 1188)
Query Neighborhood Hits	1041	Target Neighborhood Hits	543	Shared Neighborhood Hits	27
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

CT151_HUMAN
NC score	0.052919 (rank : 1061)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	1041	Target Neighborhood Hits	382	Shared Neighborhood Hits	96
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

PS1C2_HUMAN
NC score	0.052886 (rank : 1062)	θ value	θ > 10 (rank : 1342)
Query Neighborhood Hits	1041	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

SOS1_MOUSE
NC score	0.052847 (rank : 1063)	θ value	θ > 10 (rank : 1409)
Query Neighborhood Hits	1041	Target Neighborhood Hits	281	Shared Neighborhood Hits	84
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

COIA1_HUMAN
NC score	0.052783 (rank : 1064)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	1041	Target Neighborhood Hits	447	Shared Neighborhood Hits	136
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

SPR1B_MOUSE
NC score	0.052727 (rank : 1065)	θ value	0.0148317 (rank : 388)
Query Neighborhood Hits	1041	Target Neighborhood Hits	395	Shared Neighborhood Hits	88
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

CCD96_MOUSE
NC score	0.052662 (rank : 1066)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	1041	Target Neighborhood Hits	704	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

LIPA2_HUMAN
NC score	0.052651 (rank : 1067)	θ value	4.03905 (rank : 845)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1044	Shared Neighborhood Hits	105
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
NC score	0.052613 (rank : 1068)	θ value	4.03905 (rank : 846)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1282	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

CO5A2_HUMAN
NC score	0.052600 (rank : 1069)	θ value	0.00869519 (rank : 355)
Query Neighborhood Hits	1041	Target Neighborhood Hits	760	Shared Neighborhood Hits	170
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

DLK_MOUSE
NC score	0.052530 (rank : 1070)	θ value	θ > 10 (rank : 1152)
Query Neighborhood Hits	1041	Target Neighborhood Hits	374	Shared Neighborhood Hits	20
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FBN2_HUMAN
NC score	0.052517 (rank : 1071)	θ value	θ > 10 (rank : 1186)
Query Neighborhood Hits	1041	Target Neighborhood Hits	560	Shared Neighborhood Hits	31
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

CENA2_MOUSE
NC score	0.052515 (rank : 1072)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	1041	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

AUTS2_HUMAN
NC score	0.052509 (rank : 1073)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	1041	Target Neighborhood Hits	342	Shared Neighborhood Hits	114
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

GOGA3_HUMAN
NC score	0.052434 (rank : 1074)	θ value	0.0113563 (rank : 368)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1317	Shared Neighborhood Hits	124
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

FBN1_MOUSE
NC score	0.052405 (rank : 1075)	θ value	θ > 10 (rank : 1185)
Query Neighborhood Hits	1041	Target Neighborhood Hits	563	Shared Neighborhood Hits	33
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

RASA1_HUMAN
NC score	0.052386 (rank : 1076)	θ value	θ > 10 (rank : 1349)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	67
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

WNK4_HUMAN
NC score	0.052378 (rank : 1077)	θ value	θ > 10 (rank : 1480)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1043	Shared Neighborhood Hits	189
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

MLKL_MOUSE
NC score	0.052317 (rank : 1078)	θ value	θ > 10 (rank : 1259)
Query Neighborhood Hits	1041	Target Neighborhood Hits	707	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

FBN2_MOUSE
NC score	0.052288 (rank : 1079)	θ value	θ > 10 (rank : 1187)
Query Neighborhood Hits	1041	Target Neighborhood Hits	549	Shared Neighborhood Hits	29
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_HUMAN
NC score	0.052214 (rank : 1080)	θ value	θ > 10 (rank : 1184)
Query Neighborhood Hits	1041	Target Neighborhood Hits	557	Shared Neighborhood Hits	31
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

RIPK2_MOUSE
NC score	0.052139 (rank : 1081)	θ value	θ > 10 (rank : 1359)
Query Neighborhood Hits	1041	Target Neighborhood Hits	776	Shared Neighborhood Hits	66
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

ARFG3_MOUSE
NC score	0.052073 (rank : 1082)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	1041	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

RBBP6_HUMAN
NC score	0.052070 (rank : 1083)	θ value	θ > 10 (rank : 1350)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1135	Shared Neighborhood Hits	148
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SC24A_MOUSE
NC score	0.052047 (rank : 1084)	θ value	5.27518 (rank : 902)
Query Neighborhood Hits	1041	Target Neighborhood Hits	394	Shared Neighborhood Hits	109
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

DLK_HUMAN
NC score	0.052014 (rank : 1085)	θ value	θ > 10 (rank : 1151)
Query Neighborhood Hits	1041	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
NC score	0.051986 (rank : 1086)	θ value	θ > 10 (rank : 1153)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	26
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

APS_HUMAN
NC score	0.051910 (rank : 1087)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	1041	Target Neighborhood Hits	162	Shared Neighborhood Hits	55
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

ARFG1_HUMAN
NC score	0.051859 (rank : 1088)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	1041	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

TENS1_HUMAN
NC score	0.051827 (rank : 1089)	θ value	2.36792 (rank : 769)
Query Neighborhood Hits	1041	Target Neighborhood Hits	400	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

CT2NL_MOUSE
NC score	0.051822 (rank : 1090)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	1041	Target Neighborhood Hits	902	Shared Neighborhood Hits	114
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FER_HUMAN
NC score	0.051769 (rank : 1091)	θ value	θ > 10 (rank : 1189)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1278	Shared Neighborhood Hits	129
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

RBM12_MOUSE
NC score	0.051719 (rank : 1092)	θ value	θ > 10 (rank : 1351)
Query Neighborhood Hits	1041	Target Neighborhood Hits	313	Shared Neighborhood Hits	110
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

ZIMP7_HUMAN
NC score	0.051703 (rank : 1093)	θ value	0.0431538 (rank : 426)
Query Neighborhood Hits	1041	Target Neighborhood Hits	290	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

DLL1_MOUSE
NC score	0.051697 (rank : 1094)	θ value	θ > 10 (rank : 1154)
Query Neighborhood Hits	1041	Target Neighborhood Hits	456	Shared Neighborhood Hits	24
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

AGRIN_HUMAN
NC score	0.051623 (rank : 1095)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	1041	Target Neighborhood Hits	582	Shared Neighborhood Hits	59
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ZN598_HUMAN
NC score	0.051494 (rank : 1096)	θ value	θ > 10 (rank : 1485)
Query Neighborhood Hits	1041	Target Neighborhood Hits	339	Shared Neighborhood Hits	92
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

CENA2_HUMAN
NC score	0.051490 (rank : 1097)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	1041	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

ARFG1_MOUSE
NC score	0.051451 (rank : 1098)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	1041	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

MATK_MOUSE
NC score	0.051438 (rank : 1099)	θ value	θ > 10 (rank : 1251)
Query Neighborhood Hits	1041	Target Neighborhood Hits	952	Shared Neighborhood Hits	114
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MATK_HUMAN
NC score	0.051432 (rank : 1100)	θ value	θ > 10 (rank : 1250)
Query Neighborhood Hits	1041	Target Neighborhood Hits	954	Shared Neighborhood Hits	109
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

SHE_HUMAN
NC score	0.051415 (rank : 1101)	θ value	θ > 10 (rank : 1390)
Query Neighborhood Hits	1041	Target Neighborhood Hits	164	Shared Neighborhood Hits	45
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

EPHA5_HUMAN
NC score	0.051320 (rank : 1102)	θ value	0.47712 (rank : 560)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1009	Shared Neighborhood Hits	95
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

ALEX_MOUSE
NC score	0.051309 (rank : 1103)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	81
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

EP15R_MOUSE
NC score	0.051203 (rank : 1104)	θ value	θ > 10 (rank : 1178)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1135	Shared Neighborhood Hits	129
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

NEUM_MOUSE
NC score	0.051118 (rank : 1105)	θ value	θ > 10 (rank : 1281)
Query Neighborhood Hits	1041	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

ARFG3_HUMAN
NC score	0.051108 (rank : 1106)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	1041	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

SRMS_HUMAN
NC score	0.051050 (rank : 1107)	θ value	6.88961 (rank : 973)
Query Neighborhood Hits	1041	Target Neighborhood Hits	946	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
NC score	0.050986 (rank : 1108)	θ value	θ > 10 (rank : 1419)
Query Neighborhood Hits	1041	Target Neighborhood Hits	964	Shared Neighborhood Hits	115
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

TP53B_MOUSE
NC score	0.050923 (rank : 1109)	θ value	θ > 10 (rank : 1445)
Query Neighborhood Hits	1041	Target Neighborhood Hits	644	Shared Neighborhood Hits	134
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

COHA1_MOUSE
NC score	0.050909 (rank : 1110)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	1041	Target Neighborhood Hits	414	Shared Neighborhood Hits	128
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

SHC2_HUMAN
NC score	0.050845 (rank : 1111)	θ value	θ > 10 (rank : 1386)
Query Neighborhood Hits	1041	Target Neighborhood Hits	170	Shared Neighborhood Hits	51
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

LIPA1_HUMAN
NC score	0.050843 (rank : 1112)	θ value	5.27518 (rank : 891)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1294	Shared Neighborhood Hits	122
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LTBP2_MOUSE
NC score	0.050811 (rank : 1113)	θ value	θ > 10 (rank : 1239)
Query Neighborhood Hits	1041	Target Neighborhood Hits	617	Shared Neighborhood Hits	59
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CO002_HUMAN
NC score	0.050799 (rank : 1114)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	1041	Target Neighborhood Hits	387	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

SHB_MOUSE
NC score	0.050620 (rank : 1115)	θ value	θ > 10 (rank : 1383)
Query Neighborhood Hits	1041	Target Neighborhood Hits	137	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SNX9_HUMAN
NC score	0.050618 (rank : 1116)	θ value	θ > 10 (rank : 1407)
Query Neighborhood Hits	1041	Target Neighborhood Hits	148	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

VASP_HUMAN
NC score	0.050616 (rank : 1117)	θ value	θ > 10 (rank : 1462)
Query Neighborhood Hits	1041	Target Neighborhood Hits	201	Shared Neighborhood Hits	101
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

AP180_MOUSE
NC score	0.050555 (rank : 1118)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	74
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

ZC313_HUMAN
NC score	0.050536 (rank : 1119)	θ value	θ > 10 (rank : 1484)
Query Neighborhood Hits	1041	Target Neighborhood Hits	772	Shared Neighborhood Hits	104
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

WNK1_HUMAN
NC score	0.050501 (rank : 1120)	θ value	1.81305 (rank : 725)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1158	Shared Neighborhood Hits	178
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

TRIPB_HUMAN
NC score	0.050478 (rank : 1121)	θ value	0.62314 (rank : 602)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1587	Shared Neighborhood Hits	137
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

GAB1_HUMAN
NC score	0.050433 (rank : 1122)	θ value	1.38821 (rank : 672)
Query Neighborhood Hits	1041	Target Neighborhood Hits	279	Shared Neighborhood Hits	71
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MEGF9_HUMAN
NC score	0.050430 (rank : 1123)	θ value	θ > 10 (rank : 1255)
Query Neighborhood Hits	1041	Target Neighborhood Hits	557	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NIPBL_HUMAN
NC score	0.050265 (rank : 1124)	θ value	θ > 10 (rank : 1283)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1311	Shared Neighborhood Hits	178
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

IF2P_HUMAN
NC score	0.050258 (rank : 1125)	θ value	θ > 10 (rank : 1212)
Query Neighborhood Hits	1041	Target Neighborhood Hits	889	Shared Neighborhood Hits	92
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

PTN23_MOUSE
NC score	0.050253 (rank : 1126)	θ value	θ > 10 (rank : 1346)
Query Neighborhood Hits	1041	Target Neighborhood Hits	726	Shared Neighborhood Hits	210
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CSPG3_MOUSE
NC score	0.050186 (rank : 1127)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	1041	Target Neighborhood Hits	657	Shared Neighborhood Hits	83
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

SOS1_HUMAN
NC score	0.050170 (rank : 1128)	θ value	θ > 10 (rank : 1408)
Query Neighborhood Hits	1041	Target Neighborhood Hits	274	Shared Neighborhood Hits	83
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

GNRP_MOUSE
NC score	0.050157 (rank : 1129)	θ value	θ > 10 (rank : 1207)
Query Neighborhood Hits	1041	Target Neighborhood Hits	191	Shared Neighborhood Hits	43
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

ACINU_HUMAN
NC score	0.050107 (rank : 1130)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	1041	Target Neighborhood Hits	828	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NELFA_MOUSE
NC score	0.050047 (rank : 1131)	θ value	θ > 10 (rank : 1280)
Query Neighborhood Hits	1041	Target Neighborhood Hits	195	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

MY18B_HUMAN
NC score	0.050033 (rank : 1132)	θ value	θ > 10 (rank : 1275)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1299	Shared Neighborhood Hits	161
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

SREC_HUMAN
NC score	0.049916 (rank : 1133)	θ value	1.06291 (rank : 657)
Query Neighborhood Hits	1041	Target Neighborhood Hits	645	Shared Neighborhood Hits	59
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

CSKP_HUMAN
NC score	0.049797 (rank : 1134)	θ value	1.06291 (rank : 638)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1022	Shared Neighborhood Hits	202
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

GAB2_MOUSE
NC score	0.049728 (rank : 1135)	θ value	0.0148317 (rank : 384)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

MBB1A_HUMAN
NC score	0.049727 (rank : 1136)	θ value	2.36792 (rank : 749)
Query Neighborhood Hits	1041	Target Neighborhood Hits	665	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

SF3B1_MOUSE
NC score	0.049416 (rank : 1137)	θ value	2.36792 (rank : 764)
Query Neighborhood Hits	1041	Target Neighborhood Hits	352	Shared Neighborhood Hits	88
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ZN750_MOUSE
NC score	0.049364 (rank : 1138)	θ value	2.36792 (rank : 778)
Query Neighborhood Hits	1041	Target Neighborhood Hits	346	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

MTSS1_MOUSE
NC score	0.048780 (rank : 1139)	θ value	5.27518 (rank : 895)
Query Neighborhood Hits	1041	Target Neighborhood Hits	592	Shared Neighborhood Hits	140
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CSKP_MOUSE
NC score	0.048643 (rank : 1140)	θ value	6.88961 (rank : 931)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1027	Shared Neighborhood Hits	209
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

SF3B1_HUMAN
NC score	0.048602 (rank : 1141)	θ value	2.36792 (rank : 763)
Query Neighborhood Hits	1041	Target Neighborhood Hits	341	Shared Neighborhood Hits	86
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ARMX2_MOUSE
NC score	0.048597 (rank : 1142)	θ value	0.21417 (rank : 504)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	94
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

PKHA6_HUMAN
NC score	0.048570 (rank : 1143)	θ value	0.62314 (rank : 597)
Query Neighborhood Hits	1041	Target Neighborhood Hits	556	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CSPG2_MOUSE
NC score	0.048533 (rank : 1144)	θ value	1.38821 (rank : 669)
Query Neighborhood Hits	1041	Target Neighborhood Hits	711	Shared Neighborhood Hits	76
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

EPHB3_HUMAN
NC score	0.047948 (rank : 1145)	θ value	3.0926 (rank : 789)
Query Neighborhood Hits	1041	Target Neighborhood Hits	996	Shared Neighborhood Hits	92
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

NSD1_HUMAN
NC score	0.047920 (rank : 1146)	θ value	8.99809 (rank : 1022)
Query Neighborhood Hits	1041	Target Neighborhood Hits	427	Shared Neighborhood Hits	83
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TENS4_MOUSE
NC score	0.047813 (rank : 1147)	θ value	5.27518 (rank : 907)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

SPR1A_MOUSE
NC score	0.047739 (rank : 1148)	θ value	0.21417 (rank : 513)
Query Neighborhood Hits	1041	Target Neighborhood Hits	343	Shared Neighborhood Hits	70
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

DACT1_HUMAN
NC score	0.047725 (rank : 1149)	θ value	0.0563607 (rank : 431)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

EPHB3_MOUSE
NC score	0.047591 (rank : 1150)	θ value	4.03905 (rank : 836)
Query Neighborhood Hits	1041	Target Neighborhood Hits	996	Shared Neighborhood Hits	90
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

NRX2A_HUMAN
NC score	0.047394 (rank : 1151)	θ value	0.0736092 (rank : 456)
Query Neighborhood Hits	1041	Target Neighborhood Hits	614	Shared Neighborhood Hits	118
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

EPHB1_HUMAN
NC score	0.047248 (rank : 1152)	θ value	0.21417 (rank : 505)
Query Neighborhood Hits	1041	Target Neighborhood Hits	988	Shared Neighborhood Hits	88
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

ZN318_MOUSE
NC score	0.047040 (rank : 1153)	θ value	1.06291 (rank : 659)
Query Neighborhood Hits	1041	Target Neighborhood Hits	642	Shared Neighborhood Hits	102
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

GOGA3_MOUSE
NC score	0.046859 (rank : 1154)	θ value	8.99809 (rank : 1010)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1437	Shared Neighborhood Hits	117
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

AATK_HUMAN
NC score	0.046564 (rank : 1155)	θ value	5.27518 (rank : 867)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1243	Shared Neighborhood Hits	178
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

EPHA7_HUMAN
NC score	0.046312 (rank : 1156)	θ value	8.99809 (rank : 1006)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1053	Shared Neighborhood Hits	95
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

ZIM10_MOUSE
NC score	0.046173 (rank : 1157)	θ value	6.88961 (rank : 985)
Query Neighborhood Hits	1041	Target Neighborhood Hits	430	Shared Neighborhood Hits	109
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

NRX2B_HUMAN
NC score	0.045657 (rank : 1158)	θ value	0.0736092 (rank : 457)
Query Neighborhood Hits	1041	Target Neighborhood Hits	481	Shared Neighborhood Hits	103
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

WNK1_MOUSE
NC score	0.045569 (rank : 1159)	θ value	8.99809 (rank : 1038)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1179	Shared Neighborhood Hits	158
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

LAP2_HUMAN
NC score	0.045447 (rank : 1160)	θ value	6.88961 (rank : 949)
Query Neighborhood Hits	1041	Target Neighborhood Hits	499	Shared Neighborhood Hits	114
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

FRS3_HUMAN
NC score	0.045414 (rank : 1161)	θ value	9.29e-05 (rank : 222)
Query Neighborhood Hits	1041	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

DUET_HUMAN
NC score	0.045232 (rank : 1162)	θ value	0.279714 (rank : 522)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1220	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

NEST_HUMAN
NC score	0.045118 (rank : 1163)	θ value	1.38821 (rank : 676)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1305	Shared Neighborhood Hits	153
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CDAN1_HUMAN
NC score	0.044779 (rank : 1164)	θ value	1.81305 (rank : 690)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

ZIM10_HUMAN
NC score	0.044748 (rank : 1165)	θ value	5.27518 (rank : 916)
Query Neighborhood Hits	1041	Target Neighborhood Hits	577	Shared Neighborhood Hits	125
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

GA2L2_MOUSE
NC score	0.044595 (rank : 1166)	θ value	0.47712 (rank : 561)
Query Neighborhood Hits	1041	Target Neighborhood Hits	395	Shared Neighborhood Hits	101
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

CO1A2_MOUSE
NC score	0.044274 (rank : 1167)	θ value	8.99809 (rank : 1000)
Query Neighborhood Hits	1041	Target Neighborhood Hits	388	Shared Neighborhood Hits	110
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

PCNT_HUMAN
NC score	0.044232 (rank : 1168)	θ value	6.88961 (rank : 958)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1551	Shared Neighborhood Hits	151
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

COBA1_HUMAN
NC score	0.043967 (rank : 1169)	θ value	0.813845 (rank : 608)
Query Neighborhood Hits	1041	Target Neighborhood Hits	491	Shared Neighborhood Hits	133
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CSPG5_HUMAN
NC score	0.043932 (rank : 1170)	θ value	0.62314 (rank : 586)
Query Neighborhood Hits	1041	Target Neighborhood Hits	199	Shared Neighborhood Hits	62
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

STRAD_MOUSE
NC score	0.043854 (rank : 1171)	θ value	0.47712 (rank : 574)
Query Neighborhood Hits	1041	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q60924	Gene names	Stra13
Domain Architecture	No domain graphic available
Description	Retinoic acid-inducible E3 protein (Hematopoietic-specific protein E3).

CYTSA_HUMAN
NC score	0.043853 (rank : 1172)	θ value	0.47712 (rank : 558)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1138	Shared Neighborhood Hits	118
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

SRBP1_HUMAN
NC score	0.043681 (rank : 1173)	θ value	5.27518 (rank : 906)
Query Neighborhood Hits	1041	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TXLNB_MOUSE
NC score	0.043660 (rank : 1174)	θ value	5.27518 (rank : 910)
Query Neighborhood Hits	1041	Target Neighborhood Hits	640	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

GPS2_HUMAN
NC score	0.043496 (rank : 1175)	θ value	3.0926 (rank : 797)
Query Neighborhood Hits	1041	Target Neighborhood Hits	459	Shared Neighborhood Hits	74
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

ERBB2_HUMAN
NC score	0.043114 (rank : 1176)	θ value	5.27518 (rank : 882)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1073	Shared Neighborhood Hits	109
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

GAB1_MOUSE
NC score	0.043064 (rank : 1177)	θ value	3.0926 (rank : 793)
Query Neighborhood Hits	1041	Target Neighborhood Hits	233	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

DOK7_MOUSE
NC score	0.043042 (rank : 1178)	θ value	0.0563607 (rank : 432)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	45
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

CJ012_HUMAN
NC score	0.042971 (rank : 1179)	θ value	5.27518 (rank : 876)
Query Neighborhood Hits	1041	Target Neighborhood Hits	467	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

GAB2_HUMAN
NC score	0.042969 (rank : 1180)	θ value	0.365318 (rank : 536)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

TENS4_HUMAN
NC score	0.042426 (rank : 1181)	θ value	0.47712 (rank : 575)
Query Neighborhood Hits	1041	Target Neighborhood Hits	214	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

COBA1_MOUSE
NC score	0.042378 (rank : 1182)	θ value	0.813845 (rank : 609)
Query Neighborhood Hits	1041	Target Neighborhood Hits	487	Shared Neighborhood Hits	127
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

IRS2_MOUSE
NC score	0.041935 (rank : 1183)	θ value	6.88961 (rank : 946)
Query Neighborhood Hits	1041	Target Neighborhood Hits	248	Shared Neighborhood Hits	102
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

NFM_HUMAN
NC score	0.041909 (rank : 1184)	θ value	0.813845 (rank : 623)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1328	Shared Neighborhood Hits	161
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

MIA_HUMAN
NC score	0.041887 (rank : 1185)	θ value	1.06291 (rank : 650)
Query Neighborhood Hits	1041	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q16674	Gene names	MIA
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity).

CD2_HUMAN
NC score	0.041710 (rank : 1186)	θ value	4.03905 (rank : 828)
Query Neighborhood Hits	1041	Target Neighborhood Hits	504	Shared Neighborhood Hits	100
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

GON4L_MOUSE
NC score	0.041495 (rank : 1187)	θ value	4.03905 (rank : 841)
Query Neighborhood Hits	1041	Target Neighborhood Hits	455	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

EGFR_HUMAN
NC score	0.041462 (rank : 1188)	θ value	5.27518 (rank : 879)
Query Neighborhood Hits	1041	Target Neighborhood Hits	939	Shared Neighborhood Hits	75
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

JPH2_HUMAN
NC score	0.041286 (rank : 1189)	θ value	3.0926 (rank : 805)
Query Neighborhood Hits	1041	Target Neighborhood Hits	639	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TULP4_HUMAN
NC score	0.040892 (rank : 1190)	θ value	0.163984 (rank : 502)
Query Neighborhood Hits	1041	Target Neighborhood Hits	426	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MERTK_MOUSE
NC score	0.040309 (rank : 1191)	θ value	1.38821 (rank : 675)
Query Neighborhood Hits	1041	Target Neighborhood Hits	974	Shared Neighborhood Hits	70
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

BAZ2A_MOUSE
NC score	0.040097 (rank : 1192)	θ value	6.88961 (rank : 923)
Query Neighborhood Hits	1041	Target Neighborhood Hits	744	Shared Neighborhood Hits	141
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

EPN3_HUMAN
NC score	0.040049 (rank : 1193)	θ value	0.62314 (rank : 590)
Query Neighborhood Hits	1041	Target Neighborhood Hits	197	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

SPEG_MOUSE
NC score	0.039915 (rank : 1194)	θ value	3.0926 (rank : 817)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1959	Shared Neighborhood Hits	293
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CECR2_HUMAN
NC score	0.039744 (rank : 1195)	θ value	6.88961 (rank : 926)
Query Neighborhood Hits	1041	Target Neighborhood Hits	543	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

DAB1_HUMAN
NC score	0.039382 (rank : 1196)	θ value	0.813845 (rank : 610)
Query Neighborhood Hits	1041	Target Neighborhood Hits	219	Shared Neighborhood Hits	62
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

TYRO3_MOUSE
NC score	0.039376 (rank : 1197)	θ value	3.0926 (rank : 821)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1007	Shared Neighborhood Hits	72
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

MYO15_HUMAN
NC score	0.039362 (rank : 1198)	θ value	4.03905 (rank : 850)
Query Neighborhood Hits	1041	Target Neighborhood Hits	671	Shared Neighborhood Hits	180
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CO2A1_HUMAN
NC score	0.039303 (rank : 1199)	θ value	3.0926 (rank : 784)
Query Neighborhood Hits	1041	Target Neighborhood Hits	486	Shared Neighborhood Hits	129
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

GNAS1_MOUSE
NC score	0.039236 (rank : 1200)	θ value	5.27518 (rank : 885)
Query Neighborhood Hits	1041	Target Neighborhood Hits	651	Shared Neighborhood Hits	163
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

ULK1_MOUSE
NC score	0.039193 (rank : 1201)	θ value	0.813845 (rank : 631)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1214	Shared Neighborhood Hits	177
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

AFF3_HUMAN
NC score	0.038990 (rank : 1202)	θ value	0.0330416 (rank : 407)
Query Neighborhood Hits	1041	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

JIP3_HUMAN
NC score	0.038919 (rank : 1203)	θ value	2.36792 (rank : 747)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1039	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

SNIP_MOUSE
NC score	0.038886 (rank : 1204)	θ value	8.99809 (rank : 1032)
Query Neighborhood Hits	1041	Target Neighborhood Hits	319	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

CO4A3_HUMAN
NC score	0.038802 (rank : 1205)	θ value	0.279714 (rank : 519)
Query Neighborhood Hits	1041	Target Neighborhood Hits	421	Shared Neighborhood Hits	120
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

MYO15_MOUSE
NC score	0.038551 (rank : 1206)	θ value	0.47712 (rank : 569)
Query Neighborhood Hits	1041	Target Neighborhood Hits	467	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PCX3_MOUSE
NC score	0.038502 (rank : 1207)	θ value	4.03905 (rank : 851)
Query Neighborhood Hits	1041	Target Neighborhood Hits	134	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

ZN318_HUMAN
NC score	0.038491 (rank : 1208)	θ value	3.0926 (rank : 824)
Query Neighborhood Hits	1041	Target Neighborhood Hits	497	Shared Neighborhood Hits	88
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

LMBL3_MOUSE
NC score	0.038314 (rank : 1209)	θ value	0.813845 (rank : 621)
Query Neighborhood Hits	1041	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

EPN2_HUMAN
NC score	0.038169 (rank : 1210)	θ value	1.81305 (rank : 696)
Query Neighborhood Hits	1041	Target Neighborhood Hits	156	Shared Neighborhood Hits	50
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

OBSCN_HUMAN
NC score	0.038165 (rank : 1211)	θ value	1.81305 (rank : 711)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1931	Shared Neighborhood Hits	252
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ASTL_HUMAN
NC score	0.038157 (rank : 1212)	θ value	0.813845 (rank : 606)
Query Neighborhood Hits	1041	Target Neighborhood Hits	252	Shared Neighborhood Hits	71
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

CUTL2_HUMAN
NC score	0.037971 (rank : 1213)	θ value	1.06291 (rank : 640)
Query Neighborhood Hits	1041	Target Neighborhood Hits	906	Shared Neighborhood Hits	133
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CO4A1_MOUSE
NC score	0.037920 (rank : 1214)	θ value	8.99809 (rank : 1001)
Query Neighborhood Hits	1041	Target Neighborhood Hits	450	Shared Neighborhood Hits	128
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO2A1_MOUSE
NC score	0.037898 (rank : 1215)	θ value	3.0926 (rank : 785)
Query Neighborhood Hits	1041	Target Neighborhood Hits	483	Shared Neighborhood Hits	121
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

TSC1_HUMAN
NC score	0.037537 (rank : 1216)	θ value	4.03905 (rank : 865)
Query Neighborhood Hits	1041	Target Neighborhood Hits	765	Shared Neighborhood Hits	90
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ZCHC5_HUMAN
NC score	0.037124 (rank : 1217)	θ value	5.27518 (rank : 915)
Query Neighborhood Hits	1041	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

PGCB_HUMAN
NC score	0.036966 (rank : 1218)	θ value	6.88961 (rank : 959)
Query Neighborhood Hits	1041	Target Neighborhood Hits	478	Shared Neighborhood Hits	72
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ULK1_HUMAN
NC score	0.036866 (rank : 1219)	θ value	0.125558 (rank : 490)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1121	Shared Neighborhood Hits	158
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

LARP4_MOUSE
NC score	0.036579 (rank : 1220)	θ value	6.88961 (rank : 950)
Query Neighborhood Hits	1041	Target Neighborhood Hits	260	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

CING_HUMAN
NC score	0.036578 (rank : 1221)	θ value	6.88961 (rank : 927)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1275	Shared Neighborhood Hits	114
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

COBA2_MOUSE
NC score	0.036167 (rank : 1222)	θ value	2.36792 (rank : 736)
Query Neighborhood Hits	1041	Target Neighborhood Hits	501	Shared Neighborhood Hits	129
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

RTN1_HUMAN
NC score	0.036134 (rank : 1223)	θ value	5.27518 (rank : 899)
Query Neighborhood Hits	1041	Target Neighborhood Hits	173	Shared Neighborhood Hits	52
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

DGKQ_HUMAN
NC score	0.036074 (rank : 1224)	θ value	8.99809 (rank : 1003)
Query Neighborhood Hits	1041	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

FBSH_HUMAN
NC score	0.035982 (rank : 1225)	θ value	2.36792 (rank : 739)
Query Neighborhood Hits	1041	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

MORC2_HUMAN
NC score	0.035958 (rank : 1226)	θ value	0.163984 (rank : 497)
Query Neighborhood Hits	1041	Target Neighborhood Hits	207	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

FBSH_MOUSE
NC score	0.035916 (rank : 1227)	θ value	6.88961 (rank : 937)
Query Neighborhood Hits	1041	Target Neighborhood Hits	52	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R089	Gene names	Fbs1, Fbs
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

PTN4_HUMAN
NC score	0.035656 (rank : 1228)	θ value	1.38821 (rank : 680)
Query Neighborhood Hits	1041	Target Neighborhood Hits	303	Shared Neighborhood Hits	113
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

ADDB_MOUSE
NC score	0.035415 (rank : 1229)	θ value	0.62314 (rank : 581)
Query Neighborhood Hits	1041	Target Neighborhood Hits	574	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

CNOT4_MOUSE
NC score	0.034515 (rank : 1230)	θ value	2.36792 (rank : 735)
Query Neighborhood Hits	1041	Target Neighborhood Hits	277	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CTND2_HUMAN
NC score	0.034333 (rank : 1231)	θ value	0.0563607 (rank : 430)
Query Neighborhood Hits	1041	Target Neighborhood Hits	333	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CO7A1_HUMAN
NC score	0.034279 (rank : 1232)	θ value	1.81305 (rank : 693)
Query Neighborhood Hits	1041	Target Neighborhood Hits	807	Shared Neighborhood Hits	158
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

LIPA4_HUMAN
NC score	0.034234 (rank : 1233)	θ value	4.03905 (rank : 847)
Query Neighborhood Hits	1041	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

HSF1_MOUSE
NC score	0.034137 (rank : 1234)	θ value	3.0926 (rank : 801)
Query Neighborhood Hits	1041	Target Neighborhood Hits	267	Shared Neighborhood Hits	76
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HTRA3_MOUSE
NC score	0.034063 (rank : 1235)	θ value	6.88961 (rank : 943)
Query Neighborhood Hits	1041	Target Neighborhood Hits	156	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

GA2L1_MOUSE
NC score	0.033932 (rank : 1236)	θ value	3.0926 (rank : 792)
Query Neighborhood Hits	1041	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

K0319_HUMAN
NC score	0.033700 (rank : 1237)	θ value	1.81305 (rank : 705)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

RTN1_MOUSE
NC score	0.033622 (rank : 1238)	θ value	3.0926 (rank : 814)
Query Neighborhood Hits	1041	Target Neighborhood Hits	189	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

PTN3_HUMAN
NC score	0.033532 (rank : 1239)	θ value	5.27518 (rank : 898)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	101
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SPR1A_HUMAN
NC score	0.033525 (rank : 1240)	θ value	1.81305 (rank : 718)
Query Neighborhood Hits	1041	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

ZN645_HUMAN
NC score	0.033399 (rank : 1241)	θ value	1.81305 (rank : 726)
Query Neighborhood Hits	1041	Target Neighborhood Hits	265	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

DREB_HUMAN
NC score	0.033143 (rank : 1242)	θ value	6.88961 (rank : 934)
Query Neighborhood Hits	1041	Target Neighborhood Hits	450	Shared Neighborhood Hits	75
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MEF2B_MOUSE
NC score	0.032905 (rank : 1243)	θ value	0.47712 (rank : 567)
Query Neighborhood Hits	1041	Target Neighborhood Hits	218	Shared Neighborhood Hits	51
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

CRSP7_HUMAN
NC score	0.032312 (rank : 1244)	θ value	6.88961 (rank : 930)
Query Neighborhood Hits	1041	Target Neighborhood Hits	247	Shared Neighborhood Hits	66
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

SPR1B_HUMAN
NC score	0.032251 (rank : 1245)	θ value	1.81305 (rank : 719)
Query Neighborhood Hits	1041	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

IL3B2_MOUSE
NC score	0.032172 (rank : 1246)	θ value	4.03905 (rank : 844)
Query Neighborhood Hits	1041	Target Neighborhood Hits	372	Shared Neighborhood Hits	96
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

MYLK_MOUSE
NC score	0.032166 (rank : 1247)	θ value	0.279714 (rank : 524)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1489	Shared Neighborhood Hits	154
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

IF4B_HUMAN
NC score	0.032073 (rank : 1248)	θ value	1.81305 (rank : 703)
Query Neighborhood Hits	1041	Target Neighborhood Hits	417	Shared Neighborhood Hits	66
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MOR2A_MOUSE
NC score	0.032027 (rank : 1249)	θ value	1.06291 (rank : 651)
Query Neighborhood Hits	1041	Target Neighborhood Hits	220	Shared Neighborhood Hits	48
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

ULK2_HUMAN
NC score	0.031752 (rank : 1250)	θ value	2.36792 (rank : 774)
Query Neighborhood Hits	1041	Target Neighborhood Hits	979	Shared Neighborhood Hits	109
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

ATF2_HUMAN
NC score	0.031343 (rank : 1251)	θ value	2.36792 (rank : 730)
Query Neighborhood Hits	1041	Target Neighborhood Hits	402	Shared Neighborhood Hits	73
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

PRR3_HUMAN
NC score	0.030585 (rank : 1252)	θ value	0.62314 (rank : 598)
Query Neighborhood Hits	1041	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	P79522, Q5RJB5	Gene names	PRR3, CAT56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

XRCC1_MOUSE
NC score	0.030415 (rank : 1253)	θ value	5.27518 (rank : 913)
Query Neighborhood Hits	1041	Target Neighborhood Hits	242	Shared Neighborhood Hits	51
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TNIK_HUMAN
NC score	0.030321 (rank : 1254)	θ value	6.88961 (rank : 982)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1570	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

OTOR_MOUSE
NC score	0.030317 (rank : 1255)	θ value	3.0926 (rank : 809)
Query Neighborhood Hits	1041	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JIE3	Gene names	Otor, Mial
Domain Architecture
Description	Otoraplin precursor (Melanoma inhibitory activity-like protein).

ATF2_MOUSE
NC score	0.029984 (rank : 1256)	θ value	2.36792 (rank : 731)
Query Neighborhood Hits	1041	Target Neighborhood Hits	397	Shared Neighborhood Hits	74
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

CAC1G_HUMAN
NC score	0.029709 (rank : 1257)	θ value	0.279714 (rank : 518)
Query Neighborhood Hits	1041	Target Neighborhood Hits	587	Shared Neighborhood Hits	131
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CO9A1_HUMAN
NC score	0.029648 (rank : 1258)	θ value	4.03905 (rank : 832)
Query Neighborhood Hits	1041	Target Neighborhood Hits	420	Shared Neighborhood Hits	97
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

TCF20_MOUSE
NC score	0.029627 (rank : 1259)	θ value	2.36792 (rank : 768)
Query Neighborhood Hits	1041	Target Neighborhood Hits	396	Shared Neighborhood Hits	80
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

RNF25_HUMAN
NC score	0.029391 (rank : 1260)	θ value	1.06291 (rank : 655)
Query Neighborhood Hits	1041	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RECQ5_HUMAN
NC score	0.029293 (rank : 1261)	θ value	0.21417 (rank : 512)
Query Neighborhood Hits	1041	Target Neighborhood Hits	390	Shared Neighborhood Hits	96
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SOX13_MOUSE
NC score	0.029270 (rank : 1262)	θ value	0.365318 (rank : 545)
Query Neighborhood Hits	1041	Target Neighborhood Hits	495	Shared Neighborhood Hits	94
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

CO9A1_MOUSE
NC score	0.029175 (rank : 1263)	θ value	4.03905 (rank : 833)
Query Neighborhood Hits	1041	Target Neighborhood Hits	477	Shared Neighborhood Hits	106
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

HXA3_MOUSE
NC score	0.028746 (rank : 1264)	θ value	5.27518 (rank : 889)
Query Neighborhood Hits	1041	Target Neighborhood Hits	558	Shared Neighborhood Hits	139
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HXA3_HUMAN
NC score	0.028510 (rank : 1265)	θ value	0.0563607 (rank : 435)
Query Neighborhood Hits	1041	Target Neighborhood Hits	535	Shared Neighborhood Hits	129
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

SOX13_HUMAN
NC score	0.028496 (rank : 1266)	θ value	4.03905 (rank : 860)
Query Neighborhood Hits	1041	Target Neighborhood Hits	464	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SYNE1_HUMAN
NC score	0.028483 (rank : 1267)	θ value	8.99809 (rank : 1033)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1484	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

OBF1_HUMAN
NC score	0.027988 (rank : 1268)	θ value	8.99809 (rank : 1023)
Query Neighborhood Hits	1041	Target Neighborhood Hits	203	Shared Neighborhood Hits	57
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PGCA_MOUSE
NC score	0.027872 (rank : 1269)	θ value	0.47712 (rank : 570)
Query Neighborhood Hits	1041	Target Neighborhood Hits	643	Shared Neighborhood Hits	99
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

CN004_MOUSE
NC score	0.027813 (rank : 1270)	θ value	8.99809 (rank : 999)
Query Neighborhood Hits	1041	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

FBLI1_MOUSE
NC score	0.027732 (rank : 1271)	θ value	1.81305 (rank : 701)
Query Neighborhood Hits	1041	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

UBP42_HUMAN
NC score	0.027543 (rank : 1272)	θ value	1.38821 (rank : 684)
Query Neighborhood Hits	1041	Target Neighborhood Hits	445	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

HTRA1_HUMAN
NC score	0.027515 (rank : 1273)	θ value	8.99809 (rank : 1012)
Query Neighborhood Hits	1041	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

CN004_HUMAN
NC score	0.027271 (rank : 1274)	θ value	8.99809 (rank : 998)
Query Neighborhood Hits	1041	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

ASXL1_MOUSE
NC score	0.027236 (rank : 1275)	θ value	0.365318 (rank : 530)
Query Neighborhood Hits	1041	Target Neighborhood Hits	182	Shared Neighborhood Hits	39
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

DEN1A_HUMAN
NC score	0.026904 (rank : 1276)	θ value	1.81305 (rank : 695)
Query Neighborhood Hits	1041	Target Neighborhood Hits	176	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

CNOT4_HUMAN
NC score	0.026689 (rank : 1277)	θ value	1.38821 (rank : 667)
Query Neighborhood Hits	1041	Target Neighborhood Hits	207	Shared Neighborhood Hits	40
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

ZC3H3_MOUSE
NC score	0.026564 (rank : 1278)	θ value	3.0926 (rank : 823)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

FOG1_MOUSE
NC score	0.026538 (rank : 1279)	θ value	0.00665767 (rank : 349)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1237	Shared Neighborhood Hits	208
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IF4B_MOUSE
NC score	0.026401 (rank : 1280)	θ value	6.88961 (rank : 945)
Query Neighborhood Hits	1041	Target Neighborhood Hits	368	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SYNG_MOUSE
NC score	0.026322 (rank : 1281)	θ value	6.88961 (rank : 974)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

IL3RB_MOUSE
NC score	0.025219 (rank : 1282)	θ value	5.27518 (rank : 890)
Query Neighborhood Hits	1041	Target Neighborhood Hits	355	Shared Neighborhood Hits	81
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IQEC3_MOUSE
NC score	0.025153 (rank : 1283)	θ value	3.0926 (rank : 803)
Query Neighborhood Hits	1041	Target Neighborhood Hits	274	Shared Neighborhood Hits	82
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

CNTP3_HUMAN
NC score	0.024993 (rank : 1284)	θ value	1.81305 (rank : 692)
Query Neighborhood Hits	1041	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

IL4RA_MOUSE
NC score	0.024917 (rank : 1285)	θ value	8.99809 (rank : 1013)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	52
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

PEX14_MOUSE
NC score	0.024814 (rank : 1286)	θ value	0.62314 (rank : 595)
Query Neighborhood Hits	1041	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

LMBL3_HUMAN
NC score	0.024665 (rank : 1287)	θ value	0.62314 (rank : 591)
Query Neighborhood Hits	1041	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	Q96JM7, Q5VUM9, Q6P9B5	Gene names	L3MBTL3, KIAA1798
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein) (H-l(3)mbt-like protein).

GGA1_HUMAN
NC score	0.024638 (rank : 1288)	θ value	0.365318 (rank : 537)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

FAT2_HUMAN
NC score	0.024636 (rank : 1289)	θ value	0.00228821 (rank : 314)
Query Neighborhood Hits	1041	Target Neighborhood Hits	507	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

PF21A_HUMAN
NC score	0.024636 (rank : 1290)	θ value	0.813845 (rank : 626)
Query Neighborhood Hits	1041	Target Neighborhood Hits	303	Shared Neighborhood Hits	37
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

CAMKV_HUMAN
NC score	0.024244 (rank : 1291)	θ value	4.03905 (rank : 827)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1084	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

C2TA_HUMAN
NC score	0.024131 (rank : 1292)	θ value	2.36792 (rank : 733)
Query Neighborhood Hits	1041	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

HDAC5_HUMAN
NC score	0.024108 (rank : 1293)	θ value	0.0961366 (rank : 468)
Query Neighborhood Hits	1041	Target Neighborhood Hits	353	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

TRI66_HUMAN
NC score	0.023739 (rank : 1294)	θ value	2.36792 (rank : 771)
Query Neighborhood Hits	1041	Target Neighborhood Hits	479	Shared Neighborhood Hits	93
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SEZ6L_HUMAN
NC score	0.023706 (rank : 1295)	θ value	0.0330416 (rank : 412)
Query Neighborhood Hits	1041	Target Neighborhood Hits	289	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

ASPX_HUMAN
NC score	0.023671 (rank : 1296)	θ value	1.38821 (rank : 662)
Query Neighborhood Hits	1041	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

CTND2_MOUSE
NC score	0.023502 (rank : 1297)	θ value	1.06291 (rank : 639)
Query Neighborhood Hits	1041	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

MKL2_MOUSE
NC score	0.023481 (rank : 1298)	θ value	6.88961 (rank : 956)
Query Neighborhood Hits	1041	Target Neighborhood Hits	269	Shared Neighborhood Hits	58
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

FOXN1_HUMAN
NC score	0.023387 (rank : 1299)	θ value	0.125558 (rank : 480)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	86
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

ADA12_MOUSE
NC score	0.023372 (rank : 1300)	θ value	0.0330416 (rank : 406)
Query Neighborhood Hits	1041	Target Neighborhood Hits	474	Shared Neighborhood Hits	90
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

COG8_MOUSE
NC score	0.023280 (rank : 1301)	θ value	1.38821 (rank : 668)
Query Neighborhood Hits	1041	Target Neighborhood Hits	147	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

PALB2_MOUSE
NC score	0.023177 (rank : 1302)	θ value	3.0926 (rank : 810)
Query Neighborhood Hits	1041	Target Neighborhood Hits	133	Shared Neighborhood Hits	27
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

RPKL1_MOUSE
NC score	0.022878 (rank : 1303)	θ value	0.0113563 (rank : 377)
Query Neighborhood Hits	1041	Target Neighborhood Hits	704	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

ERRFI_MOUSE
NC score	0.022787 (rank : 1304)	θ value	8.99809 (rank : 1007)
Query Neighborhood Hits	1041	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

CNTP2_MOUSE
NC score	0.022697 (rank : 1305)	θ value	1.81305 (rank : 691)
Query Neighborhood Hits	1041	Target Neighborhood Hits	194	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

DCP1B_HUMAN
NC score	0.022575 (rank : 1306)	θ value	6.88961 (rank : 933)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

PHLPP_HUMAN
NC score	0.022277 (rank : 1307)	θ value	4.03905 (rank : 853)
Query Neighborhood Hits	1041	Target Neighborhood Hits	604	Shared Neighborhood Hits	107
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

CDT1_HUMAN
NC score	0.022137 (rank : 1308)	θ value	8.99809 (rank : 997)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

FHOD1_HUMAN
NC score	0.022087 (rank : 1309)	θ value	5.27518 (rank : 883)
Query Neighborhood Hits	1041	Target Neighborhood Hits	184	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

HN1L_MOUSE
NC score	0.021941 (rank : 1310)	θ value	3.0926 (rank : 799)
Query Neighborhood Hits	1041	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PGH2	Gene names	D17Ertd441e
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

TJAP1_MOUSE
NC score	0.021892 (rank : 1311)	θ value	6.88961 (rank : 979)
Query Neighborhood Hits	1041	Target Neighborhood Hits	295	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

DAB2P_HUMAN
NC score	0.021504 (rank : 1312)	θ value	0.47712 (rank : 559)
Query Neighborhood Hits	1041	Target Neighborhood Hits	303	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

TPO_MOUSE
NC score	0.021495 (rank : 1313)	θ value	5.27518 (rank : 908)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

HDAC5_MOUSE
NC score	0.021398 (rank : 1314)	θ value	0.21417 (rank : 507)
Query Neighborhood Hits	1041	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

LIMD1_MOUSE
NC score	0.021353 (rank : 1315)	θ value	6.88961 (rank : 951)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

BFAR_HUMAN
NC score	0.021235 (rank : 1316)	θ value	1.06291 (rank : 635)
Query Neighborhood Hits	1041	Target Neighborhood Hits	222	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

FXL19_MOUSE
NC score	0.020973 (rank : 1317)	θ value	1.81305 (rank : 702)
Query Neighborhood Hits	1041	Target Neighborhood Hits	217	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

RPP25_HUMAN
NC score	0.020766 (rank : 1318)	θ value	2.36792 (rank : 759)
Query Neighborhood Hits	1041	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BUL9, Q9NX88	Gene names	RPP25
Domain Architecture	No domain graphic available
Description	Ribonuclease P protein subunit p25 (EC 3.1.26.5) (RNase P protein subunit p25).

ADA19_HUMAN
NC score	0.020188 (rank : 1319)	θ value	0.62314 (rank : 580)
Query Neighborhood Hits	1041	Target Neighborhood Hits	381	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

FOXE2_HUMAN
NC score	0.020039 (rank : 1320)	θ value	0.00869519 (rank : 357)
Query Neighborhood Hits	1041	Target Neighborhood Hits	236	Shared Neighborhood Hits	54
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

ZN409_HUMAN
NC score	0.019907 (rank : 1321)	θ value	0.47712 (rank : 578)
Query Neighborhood Hits	1041	Target Neighborhood Hits	842	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

SAPS3_HUMAN
NC score	0.019732 (rank : 1322)	θ value	2.36792 (rank : 762)
Query Neighborhood Hits	1041	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).

F100B_MOUSE
NC score	0.019526 (rank : 1323)	θ value	1.81305 (rank : 699)
Query Neighborhood Hits	1041	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

RC3H1_HUMAN
NC score	0.018834 (rank : 1324)	θ value	6.88961 (rank : 965)
Query Neighborhood Hits	1041	Target Neighborhood Hits	433	Shared Neighborhood Hits	78
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

HXB3_HUMAN
NC score	0.018827 (rank : 1325)	θ value	0.000270298 (rank : 240)
Query Neighborhood Hits	1041	Target Neighborhood Hits	559	Shared Neighborhood Hits	80
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

PRGR_MOUSE
NC score	0.018647 (rank : 1326)	θ value	0.47712 (rank : 571)
Query Neighborhood Hits	1041	Target Neighborhood Hits	286	Shared Neighborhood Hits	52
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

LRP11_HUMAN
NC score	0.018360 (rank : 1327)	θ value	0.21417 (rank : 508)
Query Neighborhood Hits	1041	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

NFIP2_HUMAN
NC score	0.018254 (rank : 1328)	θ value	5.27518 (rank : 896)
Query Neighborhood Hits	1041	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

APEX2_HUMAN
NC score	0.018076 (rank : 1329)	θ value	0.62314 (rank : 583)
Query Neighborhood Hits	1041	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

BFAR_MOUSE
NC score	0.017842 (rank : 1330)	θ value	1.81305 (rank : 689)
Query Neighborhood Hits	1041	Target Neighborhood Hits	232	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

PK1L1_HUMAN
NC score	0.017817 (rank : 1331)	θ value	5.27518 (rank : 897)
Query Neighborhood Hits	1041	Target Neighborhood Hits	140	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

LRCH4_MOUSE
NC score	0.017755 (rank : 1332)	θ value	4.03905 (rank : 849)
Query Neighborhood Hits	1041	Target Neighborhood Hits	302	Shared Neighborhood Hits	39
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

TBCD1_HUMAN
NC score	0.017663 (rank : 1333)	θ value	4.03905 (rank : 862)
Query Neighborhood Hits	1041	Target Neighborhood Hits	276	Shared Neighborhood Hits	29
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

RPGF1_HUMAN
NC score	0.017585 (rank : 1334)	θ value	6.88961 (rank : 966)
Query Neighborhood Hits	1041	Target Neighborhood Hits	262	Shared Neighborhood Hits	60
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

ERCC5_MOUSE
NC score	0.017571 (rank : 1335)	θ value	4.03905 (rank : 837)
Query Neighborhood Hits	1041	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

SOX17_MOUSE
NC score	0.017510 (rank : 1336)	θ value	4.03905 (rank : 861)
Query Neighborhood Hits	1041	Target Neighborhood Hits	223	Shared Neighborhood Hits	51
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

PYGO1_HUMAN
NC score	0.017102 (rank : 1337)	θ value	4.03905 (rank : 856)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

TAF6L_MOUSE
NC score	0.017072 (rank : 1338)	θ value	6.88961 (rank : 975)
Query Neighborhood Hits	1041	Target Neighborhood Hits	146	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

HTRA2_HUMAN
NC score	0.016806 (rank : 1339)	θ value	5.27518 (rank : 887)
Query Neighborhood Hits	1041	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

CT177_HUMAN
NC score	0.016415 (rank : 1340)	θ value	3.0926 (rank : 786)
Query Neighborhood Hits	1041	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NTX9, Q9NTA3	Gene names	C20orf177
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf177.

E2F4_HUMAN
NC score	0.016271 (rank : 1341)	θ value	6.88961 (rank : 935)
Query Neighborhood Hits	1041	Target Neighborhood Hits	188	Shared Neighborhood Hits	48
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

HUWE1_HUMAN
NC score	0.016121 (rank : 1342)	θ value	6.88961 (rank : 944)
Query Neighborhood Hits	1041	Target Neighborhood Hits	443	Shared Neighborhood Hits	77
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

ZN687_HUMAN
NC score	0.015756 (rank : 1343)	θ value	0.365318 (rank : 550)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1244	Shared Neighborhood Hits	174
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

TIP60_HUMAN
NC score	0.015581 (rank : 1344)	θ value	1.81305 (rank : 723)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

MDFI_HUMAN
NC score	0.015243 (rank : 1345)	θ value	6.88961 (rank : 953)
Query Neighborhood Hits	1041	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q99750	Gene names	MDFI
Domain Architecture	No domain graphic available
Description	MyoD family inhibitor (Myogenic repressor I-mf).

HTRA2_MOUSE
NC score	0.014919 (rank : 1346)	θ value	5.27518 (rank : 888)
Query Neighborhood Hits	1041	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

ATF6B_HUMAN
NC score	0.014883 (rank : 1347)	θ value	6.88961 (rank : 922)
Query Neighborhood Hits	1041	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

PO6F1_MOUSE
NC score	0.014576 (rank : 1348)	θ value	2.36792 (rank : 756)
Query Neighborhood Hits	1041	Target Neighborhood Hits	581	Shared Neighborhood Hits	89
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

TIP60_MOUSE
NC score	0.014550 (rank : 1349)	θ value	4.03905 (rank : 863)
Query Neighborhood Hits	1041	Target Neighborhood Hits	95	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

GP108_MOUSE
NC score	0.013606 (rank : 1350)	θ value	2.36792 (rank : 742)
Query Neighborhood Hits	1041	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

MCM3A_MOUSE
NC score	0.013456 (rank : 1351)	θ value	1.81305 (rank : 708)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

PER2_MOUSE
NC score	0.013222 (rank : 1352)	θ value	8.99809 (rank : 1025)
Query Neighborhood Hits	1041	Target Neighborhood Hits	325	Shared Neighborhood Hits	56
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PYGO1_MOUSE
NC score	0.012596 (rank : 1353)	θ value	6.88961 (rank : 964)
Query Neighborhood Hits	1041	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D0P5	Gene names	Pygo1
Domain Architecture
Description	Pygopus homolog 1.

TMEPA_HUMAN
NC score	0.012314 (rank : 1354)	θ value	4.03905 (rank : 864)
Query Neighborhood Hits	1041	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q969W9, Q5TDR6, Q96B72, Q9UJD3	Gene names	TMEPAI, PMEPA1, STAG1
Domain Architecture
Description	Transmembrane prostate androgen-induced protein (Solid tumor- associated 1 protein).

HXB3_MOUSE
NC score	0.011977 (rank : 1355)	θ value	0.0563607 (rank : 436)
Query Neighborhood Hits	1041	Target Neighborhood Hits	493	Shared Neighborhood Hits	59
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

BAP1_MOUSE
NC score	0.011408 (rank : 1356)	θ value	8.99809 (rank : 991)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

K0562_MOUSE
NC score	0.011322 (rank : 1357)	θ value	8.99809 (rank : 1015)
Query Neighborhood Hits	1041	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

CSTF2_HUMAN
NC score	0.011298 (rank : 1358)	θ value	0.279714 (rank : 521)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	34
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

CC040_HUMAN
NC score	0.011076 (rank : 1359)	θ value	3.0926 (rank : 782)
Query Neighborhood Hits	1041	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UXB0, Q8TA84	Gene names	C3orf40
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf40 precursor.

FAIM2_HUMAN
NC score	0.010826 (rank : 1360)	θ value	1.81305 (rank : 700)
Query Neighborhood Hits	1041	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BWQ8, Q9UJY9, Q9Y2F7	Gene names	FAIM2, KIAA0950, LFG, TMBIM2
Domain Architecture
Description	Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Transmembrane BAX inhibitor motif-containing protein 2).

DCC_MOUSE
NC score	0.010382 (rank : 1361)	θ value	4.03905 (rank : 834)
Query Neighborhood Hits	1041	Target Neighborhood Hits	896	Shared Neighborhood Hits	122
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ETV6_HUMAN
NC score	0.010378 (rank : 1362)	θ value	3.0926 (rank : 790)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

HNF6_HUMAN
NC score	0.009885 (rank : 1363)	θ value	3.0926 (rank : 800)
Query Neighborhood Hits	1041	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBC0, Q99744, Q9UMR6	Gene names	ONECUT1, HNF6, HNF6A
Domain Architecture
Description	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1).

SEM6C_MOUSE
NC score	0.009828 (rank : 1364)	θ value	6.88961 (rank : 969)
Query Neighborhood Hits	1041	Target Neighborhood Hits	352	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

TRS85_HUMAN
NC score	0.009771 (rank : 1365)	θ value	5.27518 (rank : 909)
Query Neighborhood Hits	1041	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2L5, Q9H0L2	Gene names	KIAA1012
Domain Architecture	No domain graphic available
Description	Protein TRS85 homolog.

STAT2_MOUSE
NC score	0.009744 (rank : 1366)	θ value	3.0926 (rank : 820)
Query Neighborhood Hits	1041	Target Neighborhood Hits	175	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

TTLL5_MOUSE
NC score	0.009660 (rank : 1367)	θ value	8.99809 (rank : 1037)
Query Neighborhood Hits	1041	Target Neighborhood Hits	150	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

PSMF1_HUMAN
NC score	0.009577 (rank : 1368)	θ value	6.88961 (rank : 963)
Query Neighborhood Hits	1041	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q92530, Q9H4I1	Gene names	PSMF1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit (hPI31).

LN28B_HUMAN
NC score	0.009561 (rank : 1369)	θ value	4.03905 (rank : 848)
Query Neighborhood Hits	1041	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZN17	Gene names	LIN28B, CSDD2
Domain Architecture	No domain graphic available
Description	Lin-28 homolog B.

NFAC1_MOUSE
NC score	0.009545 (rank : 1370)	θ value	3.0926 (rank : 807)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	24
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

MEIS2_MOUSE
NC score	0.009448 (rank : 1371)	θ value	1.06291 (rank : 649)
Query Neighborhood Hits	1041	Target Neighborhood Hits	208	Shared Neighborhood Hits	21
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

KI13B_HUMAN
NC score	0.009419 (rank : 1372)	θ value	6.88961 (rank : 948)
Query Neighborhood Hits	1041	Target Neighborhood Hits	492	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

VGLL2_MOUSE
NC score	0.009355 (rank : 1373)	θ value	5.27518 (rank : 911)
Query Neighborhood Hits	1041	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGW8, Q8BWB4	Gene names	Vgll2, Vgl2, Vito1
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 2 (Vgl-2) (Protein VITO1).

DEDD_HUMAN
NC score	0.009338 (rank : 1374)	θ value	3.0926 (rank : 788)
Query Neighborhood Hits	1041	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	O75618, O60737	Gene names	DEDD, DEDPRO1, DEFT
Domain Architecture
Description	Death effector domain-containing protein (Death effector domain- containing testicular molecule) (DEDPro1) (FLDED-1).

AXN2_MOUSE
NC score	0.009207 (rank : 1375)	θ value	8.99809 (rank : 990)
Query Neighborhood Hits	1041	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

DCX_HUMAN
NC score	0.009193 (rank : 1376)	θ value	8.99809 (rank : 1002)
Query Neighborhood Hits	1041	Target Neighborhood Hits	141	Shared Neighborhood Hits	32
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

TCF7_MOUSE
NC score	0.009162 (rank : 1377)	θ value	6.88961 (rank : 976)
Query Neighborhood Hits	1041	Target Neighborhood Hits	277	Shared Neighborhood Hits	42
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

FOXH1_HUMAN
NC score	0.009156 (rank : 1378)	θ value	3.0926 (rank : 791)
Query Neighborhood Hits	1041	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

KCD18_HUMAN
NC score	0.009129 (rank : 1379)	θ value	6.88961 (rank : 947)
Query Neighborhood Hits	1041	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

HNF6_MOUSE
NC score	0.009079 (rank : 1380)	θ value	4.03905 (rank : 842)
Query Neighborhood Hits	1041	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	O08755	Gene names	Onecut1, Hnf6, Hnf6a
Domain Architecture
Description	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1).

HXD3_HUMAN
NC score	0.008924 (rank : 1381)	θ value	2.36792 (rank : 745)
Query Neighborhood Hits	1041	Target Neighborhood Hits	433	Shared Neighborhood Hits	59
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

SORC2_HUMAN
NC score	0.008883 (rank : 1382)	θ value	6.88961 (rank : 972)
Query Neighborhood Hits	1041	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

MYOD1_HUMAN
NC score	0.008676 (rank : 1383)	θ value	1.81305 (rank : 710)
Query Neighborhood Hits	1041	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

HES2_MOUSE
NC score	0.008517 (rank : 1384)	θ value	2.36792 (rank : 743)
Query Neighborhood Hits	1041	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

MEIS2_HUMAN
NC score	0.008468 (rank : 1385)	θ value	1.06291 (rank : 648)
Query Neighborhood Hits	1041	Target Neighborhood Hits	182	Shared Neighborhood Hits	18
SwissProt Accessions	O14770, Q96KI4, Q96KI5, Q9NRS1, Q9NRS2, Q9NRS3	Gene names	MEIS2, MRG1
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

CAC1B_MOUSE
NC score	0.008417 (rank : 1386)	θ value	8.99809 (rank : 995)
Query Neighborhood Hits	1041	Target Neighborhood Hits	351	Shared Neighborhood Hits	75
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

ORAI3_MOUSE
NC score	0.008347 (rank : 1387)	θ value	3.0926 (rank : 808)
Query Neighborhood Hits	1041	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P8G8	Gene names	Tmem142c, Orai3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

PANK1_HUMAN
NC score	0.008316 (rank : 1388)	θ value	3.0926 (rank : 811)
Query Neighborhood Hits	1041	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

SMAD4_MOUSE
NC score	0.008116 (rank : 1389)	θ value	1.06291 (rank : 656)
Query Neighborhood Hits	1041	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

GMEB1_MOUSE
NC score	0.007966 (rank : 1390)	θ value	3.0926 (rank : 795)
Query Neighborhood Hits	1041	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

PDCD1_HUMAN
NC score	0.007945 (rank : 1391)	θ value	2.36792 (rank : 754)
Query Neighborhood Hits	1041	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q15116, O00517	Gene names	PDCD1, PD1
Domain Architecture
Description	Programmed cell death protein 1 precursor (Protein PD-1) (hPD-1) (CD279 antigen).

ATS14_HUMAN
NC score	0.007939 (rank : 1392)	θ value	2.36792 (rank : 732)
Query Neighborhood Hits	1041	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

TTLL5_HUMAN
NC score	0.007593 (rank : 1393)	θ value	6.88961 (rank : 983)
Query Neighborhood Hits	1041	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

UBP28_MOUSE
NC score	0.007220 (rank : 1394)	θ value	2.36792 (rank : 773)
Query Neighborhood Hits	1041	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

MICA1_HUMAN
NC score	0.007189 (rank : 1395)	θ value	6.88961 (rank : 955)
Query Neighborhood Hits	1041	Target Neighborhood Hits	279	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

DLGP4_HUMAN
NC score	0.007167 (rank : 1396)	θ value	8.99809 (rank : 1004)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

MYPN_MOUSE
NC score	0.007098 (rank : 1397)	θ value	8.99809 (rank : 1020)
Query Neighborhood Hits	1041	Target Neighborhood Hits	421	Shared Neighborhood Hits	45
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

SORC1_MOUSE
NC score	0.006848 (rank : 1398)	θ value	1.81305 (rank : 717)
Query Neighborhood Hits	1041	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

TRI46_HUMAN
NC score	0.006578 (rank : 1399)	θ value	1.81305 (rank : 724)
Query Neighborhood Hits	1041	Target Neighborhood Hits	291	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RBP2_HUMAN
NC score	0.006315 (rank : 1400)	θ value	4.03905 (rank : 857)
Query Neighborhood Hits	1041	Target Neighborhood Hits	249	Shared Neighborhood Hits	44
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

TCF7_HUMAN
NC score	0.006116 (rank : 1401)	θ value	8.99809 (rank : 1035)
Query Neighborhood Hits	1041	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

ETV6_MOUSE
NC score	0.006044 (rank : 1402)	θ value	4.03905 (rank : 838)
Query Neighborhood Hits	1041	Target Neighborhood Hits	103	Shared Neighborhood Hits	13
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

PCIF1_HUMAN
NC score	0.006005 (rank : 1403)	θ value	8.99809 (rank : 1024)
Query Neighborhood Hits	1041	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

GP123_HUMAN
NC score	0.005980 (rank : 1404)	θ value	8.99809 (rank : 1011)
Query Neighborhood Hits	1041	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

CTBP2_HUMAN
NC score	0.005908 (rank : 1405)	θ value	3.0926 (rank : 787)
Query Neighborhood Hits	1041	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P56545, O43449	Gene names	CTBP2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

ZN516_MOUSE
NC score	0.005891 (rank : 1406)	θ value	0.0563607 (rank : 443)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1197	Shared Neighborhood Hits	160
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

C1QA_HUMAN
NC score	0.005678 (rank : 1407)	θ value	8.99809 (rank : 994)
Query Neighborhood Hits	1041	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

MEFV_HUMAN
NC score	0.005549 (rank : 1408)	θ value	1.06291 (rank : 647)
Query Neighborhood Hits	1041	Target Neighborhood Hits	431	Shared Neighborhood Hits	53
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

BNC2_HUMAN
NC score	0.005547 (rank : 1409)	θ value	8.99809 (rank : 993)
Query Neighborhood Hits	1041	Target Neighborhood Hits	439	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

E41LB_HUMAN
NC score	0.005486 (rank : 1410)	θ value	2.36792 (rank : 738)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

TM55A_HUMAN
NC score	0.004934 (rank : 1411)	θ value	6.88961 (rank : 980)
Query Neighborhood Hits	1041	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4L2, Q68CU2	Gene names	TMEM55A
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55A (EC 3.1.3.-) (Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase II).

MSH4_HUMAN
NC score	0.004928 (rank : 1412)	θ value	5.27518 (rank : 893)
Query Neighborhood Hits	1041	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	O15457, Q8NEB3, Q9UNP8	Gene names	MSH4
Domain Architecture
Description	MutS protein homolog 4.

TTLL4_HUMAN
NC score	0.004770 (rank : 1413)	θ value	8.99809 (rank : 1036)
Query Neighborhood Hits	1041	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

CT075_MOUSE
NC score	0.004748 (rank : 1414)	θ value	1.38821 (rank : 670)
Query Neighborhood Hits	1041	Target Neighborhood Hits	358	Shared Neighborhood Hits	26
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

IRF7_HUMAN
NC score	0.004417 (rank : 1415)	θ value	8.99809 (rank : 1014)
Query Neighborhood Hits	1041	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

FLI1_MOUSE
NC score	0.004156 (rank : 1416)	θ value	2.36792 (rank : 740)
Query Neighborhood Hits	1041	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	P26323	Gene names	Fli1, Fli-1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Retroviral integration site protein Fli-1).

FOXGA_HUMAN
NC score	0.003418 (rank : 1417)	θ value	5.27518 (rank : 884)
Query Neighborhood Hits	1041	Target Neighborhood Hits	132	Shared Neighborhood Hits	23
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

GAK8_HUMAN
NC score	0.003385 (rank : 1418)	θ value	3.0926 (rank : 794)
Query Neighborhood Hits	1041	Target Neighborhood Hits	145	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TBX18_HUMAN
NC score	0.003188 (rank : 1419)	θ value	2.36792 (rank : 767)
Query Neighborhood Hits	1041	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

FOXJ1_MOUSE
NC score	0.003095 (rank : 1420)	θ value	6.88961 (rank : 940)
Query Neighborhood Hits	1041	Target Neighborhood Hits	209	Shared Neighborhood Hits	32
SwissProt Accessions	Q61660	Gene names	Foxj1, Fkhl13, Hfh4
Domain Architecture
Description	Forkhead box protein J1 (Forkhead-related protein FKHL13) (Hepatocyte nuclear factor 3 forkhead homolog 4) (HFH-4).

RX_HUMAN
NC score	0.003034 (rank : 1421)	θ value	3.0926 (rank : 815)
Query Neighborhood Hits	1041	Target Neighborhood Hits	423	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

PO3F4_HUMAN
NC score	0.003027 (rank : 1422)	θ value	0.813845 (rank : 627)
Query Neighborhood Hits	1041	Target Neighborhood Hits	297	Shared Neighborhood Hits	22
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

KCNQ4_HUMAN
NC score	0.002659 (rank : 1423)	θ value	1.81305 (rank : 707)
Query Neighborhood Hits	1041	Target Neighborhood Hits	136	Shared Neighborhood Hits	11
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

PRGR_HUMAN
NC score	0.002640 (rank : 1424)	θ value	6.88961 (rank : 962)
Query Neighborhood Hits	1041	Target Neighborhood Hits	163	Shared Neighborhood Hits	24
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

FLI1_HUMAN
NC score	0.002637 (rank : 1425)	θ value	6.88961 (rank : 939)
Query Neighborhood Hits	1041	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q01543, Q14319, Q92480, Q9UE07	Gene names	FLI1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Fli-1 proto- oncogene) (ERGB transcription factor).

PITM2_HUMAN
NC score	0.002594 (rank : 1426)	θ value	4.03905 (rank : 854)
Query Neighborhood Hits	1041	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

DCJ14_MOUSE
NC score	0.002418 (rank : 1427)	θ value	4.03905 (rank : 835)
Query Neighborhood Hits	1041	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	Q921R4, Q3TX73, Q8BUU3, Q9CYB7	Gene names	Dnajc14
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14.

SCNND_HUMAN
NC score	0.002417 (rank : 1428)	θ value	6.88961 (rank : 968)
Query Neighborhood Hits	1041	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P51172, Q5T7L3, Q8NA24	Gene names	SCNN1D, DNACH
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit delta (Epithelial Na+ channel subunit delta) (Delta ENaC) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED) (Delta NaCH).

FOXQ1_MOUSE
NC score	0.002361 (rank : 1429)	θ value	8.99809 (rank : 1009)
Query Neighborhood Hits	1041	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	O70220	Gene names	Foxq1, Hfh1, Hfh1l
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1) (HFH-1l).

PR285_HUMAN
NC score	0.002282 (rank : 1430)	θ value	8.99809 (rank : 1026)
Query Neighborhood Hits	1041	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

PAPOB_HUMAN
NC score	0.002175 (rank : 1431)	θ value	6.88961 (rank : 957)
Query Neighborhood Hits	1041	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRJ5, Q8NE14	Gene names	PAPOLB, PAPT
Domain Architecture
Description	Poly(A) polymerase beta (EC 2.7.7.19) (PAP beta) (Polynucleotide adenylyltransferase beta) (Testis-specific poly(A) polymerase).

AT8B3_HUMAN
NC score	0.001597 (rank : 1432)	θ value	6.88961 (rank : 921)
Query Neighborhood Hits	1041	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	O60423, Q8IVB8, Q8N4Y8, Q96M22	Gene names	ATP8B3, ATP1K, FOS37502_2
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IK (EC 3.6.3.1) (ATPase class I type 8B member 3).

AT8B2_HUMAN
NC score	0.001565 (rank : 1433)	θ value	3.0926 (rank : 781)
Query Neighborhood Hits	1041	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	P98198, Q96I43, Q96NQ7	Gene names	ATP8B2, ATPID, KIAA1137
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase ID (EC 3.6.3.1) (ATPase class I type 8B member 2).

FOXI1_MOUSE
NC score	0.001310 (rank : 1434)	θ value	8.99809 (rank : 1008)
Query Neighborhood Hits	1041	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	Q922I5, Q5SRI5, Q9D299	Gene names	Foxi1
Domain Architecture	No domain graphic available
Description	Forkhead box protein I1.

CPT1A_HUMAN
NC score	0.001159 (rank : 1435)	θ value	5.27518 (rank : 877)
Query Neighborhood Hits	1041	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P50416, Q8TCU0, Q9BWK0	Gene names	CPT1A, CPT1
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, liver isoform (EC 2.3.1.21) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A).

KCNB1_MOUSE
NC score	0.000918 (rank : 1436)	θ value	0.47712 (rank : 566)
Query Neighborhood Hits	1041	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

EVX1_HUMAN
NC score	0.000916 (rank : 1437)	θ value	1.81305 (rank : 698)
Query Neighborhood Hits	1041	Target Neighborhood Hits	349	Shared Neighborhood Hits	29
SwissProt Accessions	P49640	Gene names	EVX1
Domain Architecture
Description	Homeobox even-skipped homolog protein 1 (EVX-1).

AT8B1_HUMAN
NC score	0.000858 (rank : 1438)	θ value	6.88961 (rank : 920)
Query Neighborhood Hits	1041	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	O43520, Q9BTP8	Gene names	ATP8B1, ATPIC, FIC1, PFIC
Domain Architecture
Description	Probable phospholipid-transporting ATPase IC (EC 3.6.3.1) (Familial intrahepatic cholestasis type 1) (ATPase class I type 8B member 1).

HXB13_HUMAN
NC score	0.000549 (rank : 1439)	θ value	2.36792 (rank : 744)
Query Neighborhood Hits	1041	Target Neighborhood Hits	377	Shared Neighborhood Hits	24
SwissProt Accessions	Q92826, Q96QM4, Q99810	Gene names	HOXB13
Domain Architecture
Description	Homeobox protein Hox-B13.

PO3F4_MOUSE
NC score	0.000537 (rank : 1440)	θ value	6.88961 (rank : 961)
Query Neighborhood Hits	1041	Target Neighborhood Hits	281	Shared Neighborhood Hits	19
SwissProt Accessions	P62515, P25216	Gene names	Pou3f4, Brn-4, Brn4, Otf9
Domain Architecture	No domain graphic available
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

HXB13_MOUSE
NC score	0.000229 (rank : 1441)	θ value	3.0926 (rank : 802)
Query Neighborhood Hits	1041	Target Neighborhood Hits	384	Shared Neighborhood Hits	26
SwissProt Accessions	P70321, Q80Y12	Gene names	Hoxb13
Domain Architecture
Description	Homeobox protein Hox-B13.

RX_MOUSE
NC score	-0.000140 (rank : 1442)	θ value	8.99809 (rank : 1030)
Query Neighborhood Hits	1041	Target Neighborhood Hits	429	Shared Neighborhood Hits	41
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

GP124_MOUSE
NC score	-0.000199 (rank : 1443)	θ value	3.0926 (rank : 796)
Query Neighborhood Hits	1041	Target Neighborhood Hits	423	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

ZEP2_MOUSE
NC score	-0.000232 (rank : 1444)	θ value	8.99809 (rank : 1040)
Query Neighborhood Hits	1041	Target Neighborhood Hits	964	Shared Neighborhood Hits	103
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

PUNC_MOUSE
NC score	-0.000956 (rank : 1445)	θ value	1.81305 (rank : 712)
Query Neighborhood Hits	1041	Target Neighborhood Hits	501	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ANDR_MOUSE
NC score	-0.001021 (rank : 1446)	θ value	8.99809 (rank : 988)
Query Neighborhood Hits	1041	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

MSX1_HUMAN
NC score	-0.001217 (rank : 1447)	θ value	8.99809 (rank : 1018)
Query Neighborhood Hits	1041	Target Neighborhood Hits	374	Shared Neighborhood Hits	28
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

ZEP2_HUMAN
NC score	-0.001220 (rank : 1448)	θ value	8.99809 (rank : 1039)
Query Neighborhood Hits	1041	Target Neighborhood Hits	937	Shared Neighborhood Hits	96
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZBTB3_HUMAN
NC score	-0.001573 (rank : 1449)	θ value	0.365318 (rank : 549)
Query Neighborhood Hits	1041	Target Neighborhood Hits	910	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

LIRB4_HUMAN
NC score	-0.001757 (rank : 1450)	θ value	6.88961 (rank : 952)
Query Neighborhood Hits	1041	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

RTN4R_MOUSE
NC score	-0.001828 (rank : 1451)	θ value	2.36792 (rank : 760)
Query Neighborhood Hits	1041	Target Neighborhood Hits	293	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

GLT12_MOUSE
NC score	-0.001957 (rank : 1452)	θ value	4.03905 (rank : 840)
Query Neighborhood Hits	1041	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGT9	Gene names	Galnt12
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12).

BMP3B_HUMAN
NC score	-0.002320 (rank : 1453)	θ value	8.99809 (rank : 992)
Query Neighborhood Hits	1041	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	P55107, Q9UCX6	Gene names	GDF10, BMP3B
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10) (Bone-inducing protein) (BIP).

DLX4_MOUSE
NC score	-0.002403 (rank : 1454)	θ value	8.99809 (rank : 1005)
Query Neighborhood Hits	1041	Target Neighborhood Hits	352	Shared Neighborhood Hits	22
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

SALL2_MOUSE
NC score	-0.002611 (rank : 1455)	θ value	4.03905 (rank : 858)
Query Neighborhood Hits	1041	Target Neighborhood Hits	836	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

SLIK3_MOUSE
NC score	-0.003448 (rank : 1456)	θ value	4.03905 (rank : 859)
Query Neighborhood Hits	1041	Target Neighborhood Hits	308	Shared Neighborhood Hits	19
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

PCDAB_HUMAN
NC score	-0.003568 (rank : 1457)	θ value	3.0926 (rank : 812)
Query Neighborhood Hits	1041	Target Neighborhood Hits	211	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5I1, O75279	Gene names	PCDHA11
Domain Architecture
Description	Protocadherin alpha 11 precursor (PCDH-alpha11).

ZN447_HUMAN
NC score	-0.004259 (rank : 1458)	θ value	2.36792 (rank : 777)
Query Neighborhood Hits	1041	Target Neighborhood Hits	899	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

SALL2_HUMAN
NC score	-0.004459 (rank : 1459)	θ value	6.88961 (rank : 967)
Query Neighborhood Hits	1041	Target Neighborhood Hits	835	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

SALL1_MOUSE
NC score	-0.005266 (rank : 1460)	θ value	5.27518 (rank : 901)
Query Neighborhood Hits	1041	Target Neighborhood Hits	826	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

KLF17_HUMAN
NC score	-0.005281 (rank : 1461)	θ value	0.813845 (rank : 618)
Query Neighborhood Hits	1041	Target Neighborhood Hits	882	Shared Neighborhood Hits	93
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

CAD15_MOUSE
NC score	-0.005362 (rank : 1462)	θ value	8.99809 (rank : 996)
Query Neighborhood Hits	1041	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	P33146, Q9QYZ7	Gene names	Cdh15, Cdh14
Domain Architecture
Description	Cadherin-15 precursor (Muscle-cadherin) (M-cadherin) (Cadherin-14).

EGR4_HUMAN
NC score	-0.005627 (rank : 1463)	θ value	0.125558 (rank : 479)
Query Neighborhood Hits	1041	Target Neighborhood Hits	939	Shared Neighborhood Hits	88
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

SALL1_HUMAN
NC score	-0.007196 (rank : 1464)	θ value	2.36792 (rank : 761)
Query Neighborhood Hits	1041	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

ZN142_HUMAN
NC score	-0.007614 (rank : 1465)	θ value	1.38821 (rank : 686)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1007	Shared Neighborhood Hits	110
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

RBBP7_HUMAN
NC score	-0.008163 (rank : 1466)	θ value	8.99809 (rank : 1027)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
NC score	-0.008175 (rank : 1467)	θ value	8.99809 (rank : 1028)
Query Neighborhood Hits	1041	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

ZSCA5_HUMAN
NC score	-0.008687 (rank : 1468)	θ value	0.0563607 (rank : 444)
Query Neighborhood Hits	1041	Target Neighborhood Hits	862	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

TMPS9_MOUSE
NC score	-0.009137 (rank : 1469)	θ value	6.88961 (rank : 981)
Query Neighborhood Hits	1041	Target Neighborhood Hits	296	Shared Neighborhood Hits	20
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

GLI1_MOUSE
NC score	-0.009733 (rank : 1470)	θ value	6.88961 (rank : 941)
Query Neighborhood Hits	1041	Target Neighborhood Hits	785	Shared Neighborhood Hits	62
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

GLIS1_HUMAN
NC score	-0.010143 (rank : 1471)	θ value	6.88961 (rank : 942)
Query Neighborhood Hits	1041	Target Neighborhood Hits	748	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

HIC1_MOUSE
NC score	-0.010217 (rank : 1472)	θ value	5.27518 (rank : 886)
Query Neighborhood Hits	1041	Target Neighborhood Hits	863	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

EVI1_MOUSE
NC score	-0.010479 (rank : 1473)	θ value	1.06291 (rank : 642)
Query Neighborhood Hits	1041	Target Neighborhood Hits	826	Shared Neighborhood Hits	57
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

ZBT16_HUMAN
NC score	-0.010999 (rank : 1474)	θ value	0.47712 (rank : 576)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1010	Shared Neighborhood Hits	81
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

MAZ_MOUSE
NC score	-0.011172 (rank : 1475)	θ value	8.99809 (rank : 1017)
Query Neighborhood Hits	1041	Target Neighborhood Hits	745	Shared Neighborhood Hits	52
SwissProt Accessions	P56671, Q9R1W0	Gene names	Maz
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1).

DRD2_MOUSE
NC score	-0.011450 (rank : 1476)	θ value	0.62314 (rank : 589)
Query Neighborhood Hits	1041	Target Neighborhood Hits	779	Shared Neighborhood Hits	12
SwissProt Accessions	P61168, P13953	Gene names	Drd2
Domain Architecture
Description	D(2) dopamine receptor (Dopamine D2 receptor).

ZN334_HUMAN
NC score	-0.011709 (rank : 1477)	θ value	0.0148317 (rank : 391)
Query Neighborhood Hits	1041	Target Neighborhood Hits	778	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCZ1, Q5T6U2, Q9NVW4	Gene names	ZNF334
Domain Architecture
Description	Zinc finger protein 334.

ZN710_HUMAN
NC score	-0.011748 (rank : 1478)	θ value	0.47712 (rank : 579)
Query Neighborhood Hits	1041	Target Neighborhood Hits	796	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

DRD2_HUMAN
NC score	-0.012254 (rank : 1479)	θ value	1.38821 (rank : 671)
Query Neighborhood Hits	1041	Target Neighborhood Hits	774	Shared Neighborhood Hits	8
SwissProt Accessions	P14416, Q9NZR3, Q9UPA9	Gene names	DRD2
Domain Architecture
Description	D(2) dopamine receptor (Dopamine D2 receptor).

ZIC1_HUMAN
NC score	-0.012439 (rank : 1480)	θ value	4.03905 (rank : 866)
Query Neighborhood Hits	1041	Target Neighborhood Hits	710	Shared Neighborhood Hits	34
SwissProt Accessions	Q15915	Gene names	ZIC1, ZIC
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1).

ZIC1_MOUSE
NC score	-0.012602 (rank : 1481)	θ value	6.88961 (rank : 984)
Query Neighborhood Hits	1041	Target Neighborhood Hits	716	Shared Neighborhood Hits	37
SwissProt Accessions	P46684	Gene names	Zic1, Zic
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1).

ZN384_HUMAN
NC score	-0.012733 (rank : 1482)	θ value	2.36792 (rank : 776)
Query Neighborhood Hits	1041	Target Neighborhood Hits	764	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF68, O15407, Q8N938	Gene names	ZNF384, CAGH1, CIZ, NMP4
Domain Architecture	No domain graphic available
Description	Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein).

MTR1L_HUMAN
NC score	-0.012932 (rank : 1483)	θ value	5.27518 (rank : 894)
Query Neighborhood Hits	1041	Target Neighborhood Hits	1180	Shared Neighborhood Hits	76
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

ZBT7A_HUMAN
NC score	-0.013543 (rank : 1484)	θ value	5.27518 (rank : 914)
Query Neighborhood Hits	1041	Target Neighborhood Hits	823	Shared Neighborhood Hits	36
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).

ADA1D_MOUSE
NC score	-0.015528 (rank : 1485)	θ value	0.813845 (rank : 604)
Query Neighborhood Hits	1041	Target Neighborhood Hits	874	Shared Neighborhood Hits	7
SwissProt Accessions	P97714, Q61619	Gene names	Adra1d, Adra1a, Gpcr8
Domain Architecture
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D- adrenoreceptor) (Alpha-1A adrenergic receptor).

ADA2C_MOUSE
NC score	-0.015793 (rank : 1486)	θ value	6.88961 (rank : 918)
Query Neighborhood Hits	1041	Target Neighborhood Hits	792	Shared Neighborhood Hits	11
SwissProt Accessions	Q01337	Gene names	Adra2c
Domain Architecture
Description	Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2C adrenoreceptor) (Alpha-2 adrenergic receptor subtype C4).