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Network neighborhood for query Sequence : CTND2_MOUSE

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CTND2_MOUSE
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CTND2_HUMAN
θ value	0 (rank : 1)	NC score	0.985263 (rank : 2)
Query Neighborhood Hits	227	Target Neighborhood Hits	333	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CTND2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	227	Target Neighborhood Hits	227	Shared Neighborhood Hits	227
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

PKP4_HUMAN
θ value	0 (rank : 3)	NC score	0.964321 (rank : 3)
Query Neighborhood Hits	227	Target Neighborhood Hits	107	Shared Neighborhood Hits	45
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP4_MOUSE
θ value	0 (rank : 4)	NC score	0.964230 (rank : 4)
Query Neighborhood Hits	227	Target Neighborhood Hits	129	Shared Neighborhood Hits	49
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

ARVC_MOUSE
θ value	3.28708e-135 (rank : 5)	NC score	0.938610 (rank : 5)
Query Neighborhood Hits	227	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

ARVC_HUMAN
θ value	2.78268e-134 (rank : 6)	NC score	0.936130 (rank : 6)
Query Neighborhood Hits	227	Target Neighborhood Hits	95	Shared Neighborhood Hits	36
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

CTND1_HUMAN
θ value	8.67031e-128 (rank : 7)	NC score	0.931167 (rank : 8)
Query Neighborhood Hits	227	Target Neighborhood Hits	67	Shared Neighborhood Hits	32
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_MOUSE
θ value	5.61992e-127 (rank : 8)	NC score	0.932436 (rank : 7)
Query Neighborhood Hits	227	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

PKP1_MOUSE
θ value	5.00389e-67 (rank : 9)	NC score	0.888669 (rank : 10)
Query Neighborhood Hits	227	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP2_HUMAN
θ value	1.04338e-64 (rank : 10)	NC score	0.894331 (rank : 9)
Query Neighborhood Hits	227	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PKP1_HUMAN
θ value	5.17823e-64 (rank : 11)	NC score	0.886419 (rank : 12)
Query Neighborhood Hits	227	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP3_HUMAN
θ value	2.17557e-62 (rank : 12)	NC score	0.886555 (rank : 11)
Query Neighborhood Hits	227	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
θ value	3.47335e-60 (rank : 13)	NC score	0.884846 (rank : 13)
Query Neighborhood Hits	227	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PLAK_MOUSE
θ value	4.92598e-06 (rank : 14)	NC score	0.273574 (rank : 17)
Query Neighborhood Hits	227	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

CTNB1_HUMAN
θ value	1.09739e-05 (rank : 15)	NC score	0.300423 (rank : 16)
Query Neighborhood Hits	227	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	1.09739e-05 (rank : 16)	NC score	0.300490 (rank : 15)
Query Neighborhood Hits	227	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

APC_MOUSE
θ value	2.44474e-05 (rank : 17)	NC score	0.244795 (rank : 18)
Query Neighborhood Hits	227	Target Neighborhood Hits	441	Shared Neighborhood Hits	50
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
θ value	3.19293e-05 (rank : 18)	NC score	0.241743 (rank : 19)
Query Neighborhood Hits	227	Target Neighborhood Hits	603	Shared Neighborhood Hits	64
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

MUC13_MOUSE
θ value	4.1701e-05 (rank : 19)	NC score	0.099454 (rank : 35)
Query Neighborhood Hits	227	Target Neighborhood Hits	447	Shared Neighborhood Hits	36
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

IMA7_MOUSE
θ value	0.000461057 (rank : 20)	NC score	0.155399 (rank : 22)
Query Neighborhood Hits	227	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA7_HUMAN
θ value	0.00134147 (rank : 21)	NC score	0.150889 (rank : 23)
Query Neighborhood Hits	227	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

ARMC4_HUMAN
θ value	0.00228821 (rank : 22)	NC score	0.370310 (rank : 14)
Query Neighborhood Hits	227	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

BSN_MOUSE
θ value	0.00228821 (rank : 23)	NC score	0.078955 (rank : 41)
Query Neighborhood Hits	227	Target Neighborhood Hits	2057	Shared Neighborhood Hits	132
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ATN1_HUMAN
θ value	0.00390308 (rank : 24)	NC score	0.109517 (rank : 33)
Query Neighborhood Hits	227	Target Neighborhood Hits	676	Shared Neighborhood Hits	69
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

PLAK_HUMAN
θ value	0.00390308 (rank : 25)	NC score	0.234224 (rank : 20)
Query Neighborhood Hits	227	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

SRRM2_MOUSE
θ value	0.00509761 (rank : 26)	NC score	0.087818 (rank : 37)
Query Neighborhood Hits	227	Target Neighborhood Hits	1470	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

GDS1_HUMAN
θ value	0.00665767 (rank : 27)	NC score	0.193781 (rank : 21)
Query Neighborhood Hits	227	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

CK024_HUMAN
θ value	0.00869519 (rank : 28)	NC score	0.097431 (rank : 36)
Query Neighborhood Hits	227	Target Neighborhood Hits	408	Shared Neighborhood Hits	55
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

IMA5_HUMAN
θ value	0.0193708 (rank : 29)	NC score	0.145260 (rank : 24)
Query Neighborhood Hits	227	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

PARM1_MOUSE
θ value	0.0193708 (rank : 30)	NC score	0.104800 (rank : 34)
Query Neighborhood Hits	227	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

TAF6_MOUSE
θ value	0.0193708 (rank : 31)	NC score	0.075472 (rank : 43)
Query Neighborhood Hits	227	Target Neighborhood Hits	110	Shared Neighborhood Hits	21
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

K0999_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.010165 (rank : 187)
Query Neighborhood Hits	227	Target Neighborhood Hits	899	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

NACAM_MOUSE
θ value	0.0330416 (rank : 33)	NC score	0.084982 (rank : 39)
Query Neighborhood Hits	227	Target Neighborhood Hits	1866	Shared Neighborhood Hits	131
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DVL2_MOUSE
θ value	0.0431538 (rank : 34)	NC score	0.032113 (rank : 106)
Query Neighborhood Hits	227	Target Neighborhood Hits	233	Shared Neighborhood Hits	18
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

T22D2_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.085781 (rank : 38)
Query Neighborhood Hits	227	Target Neighborhood Hits	250	Shared Neighborhood Hits	41
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

ZCH14_HUMAN
θ value	0.0431538 (rank : 36)	NC score	0.068652 (rank : 47)
Query Neighborhood Hits	227	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

MINT_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.046313 (rank : 71)
Query Neighborhood Hits	227	Target Neighborhood Hits	1291	Shared Neighborhood Hits	83
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUC1_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.078185 (rank : 42)
Query Neighborhood Hits	227	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

RPB1_HUMAN
θ value	0.0563607 (rank : 39)	NC score	0.069767 (rank : 46)
Query Neighborhood Hits	227	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.0563607 (rank : 40)	NC score	0.069910 (rank : 45)
Query Neighborhood Hits	227	Target Neighborhood Hits	363	Shared Neighborhood Hits	42
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

BSN_HUMAN
θ value	0.0961366 (rank : 41)	NC score	0.060286 (rank : 54)
Query Neighborhood Hits	227	Target Neighborhood Hits	1537	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

EWS_HUMAN
θ value	0.0961366 (rank : 42)	NC score	0.065609 (rank : 49)
Query Neighborhood Hits	227	Target Neighborhood Hits	249	Shared Neighborhood Hits	21
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

NELFA_HUMAN
θ value	0.125558 (rank : 43)	NC score	0.072741 (rank : 44)
Query Neighborhood Hits	227	Target Neighborhood Hits	161	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

IF4G1_HUMAN
θ value	0.163984 (rank : 44)	NC score	0.043240 (rank : 78)
Query Neighborhood Hits	227	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

LPIN3_HUMAN
θ value	0.163984 (rank : 45)	NC score	0.029959 (rank : 113)
Query Neighborhood Hits	227	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

MLL3_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.046090 (rank : 73)
Query Neighborhood Hits	227	Target Neighborhood Hits	1644	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PHLB1_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.043506 (rank : 77)
Query Neighborhood Hits	227	Target Neighborhood Hits	1038	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SALL3_HUMAN
θ value	0.163984 (rank : 48)	NC score	0.012168 (rank : 174)
Query Neighborhood Hits	227	Target Neighborhood Hits	1066	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

STK3_HUMAN
θ value	0.163984 (rank : 49)	NC score	0.005342 (rank : 207)
Query Neighborhood Hits	227	Target Neighborhood Hits	861	Shared Neighborhood Hits	18
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

IMA2_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.135700 (rank : 25)
Query Neighborhood Hits	227	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

MAP1A_HUMAN
θ value	0.21417 (rank : 51)	NC score	0.036555 (rank : 95)
Query Neighborhood Hits	227	Target Neighborhood Hits	1626	Shared Neighborhood Hits	75
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MTSS1_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.042558 (rank : 81)
Query Neighborhood Hits	227	Target Neighborhood Hits	504	Shared Neighborhood Hits	42
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

PHLB1_MOUSE
θ value	0.21417 (rank : 53)	NC score	0.046142 (rank : 72)
Query Neighborhood Hits	227	Target Neighborhood Hits	678	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RBM14_MOUSE
θ value	0.21417 (rank : 54)	NC score	0.035908 (rank : 98)
Query Neighborhood Hits	227	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

GOGB1_HUMAN
θ value	0.279714 (rank : 55)	NC score	0.011270 (rank : 179)
Query Neighborhood Hits	227	Target Neighborhood Hits	2297	Shared Neighborhood Hits	50
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SYNJ1_HUMAN
θ value	0.279714 (rank : 56)	NC score	0.044641 (rank : 76)
Query Neighborhood Hits	227	Target Neighborhood Hits	498	Shared Neighborhood Hits	54
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ANKS6_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.020414 (rank : 141)
Query Neighborhood Hits	227	Target Neighborhood Hits	411	Shared Neighborhood Hits	20
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CHD9_MOUSE
θ value	0.365318 (rank : 58)	NC score	0.021029 (rank : 138)
Query Neighborhood Hits	227	Target Neighborhood Hits	427	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

IMA3_HUMAN
θ value	0.365318 (rank : 59)	NC score	0.119753 (rank : 30)
Query Neighborhood Hits	227	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
θ value	0.365318 (rank : 60)	NC score	0.119934 (rank : 29)
Query Neighborhood Hits	227	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

NFH_MOUSE
θ value	0.365318 (rank : 61)	NC score	0.036203 (rank : 96)
Query Neighborhood Hits	227	Target Neighborhood Hits	2247	Shared Neighborhood Hits	116
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PER3_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.043160 (rank : 79)
Query Neighborhood Hits	227	Target Neighborhood Hits	479	Shared Neighborhood Hits	61
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

RBM14_HUMAN
θ value	0.365318 (rank : 63)	NC score	0.033774 (rank : 100)
Query Neighborhood Hits	227	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

EMSY_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.043048 (rank : 80)
Query Neighborhood Hits	227	Target Neighborhood Hits	296	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

EWS_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.056886 (rank : 60)
Query Neighborhood Hits	227	Target Neighborhood Hits	271	Shared Neighborhood Hits	22
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

IMA2_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.134990 (rank : 26)
Query Neighborhood Hits	227	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

MAGC1_HUMAN
θ value	0.47712 (rank : 67)	NC score	0.029605 (rank : 114)
Query Neighborhood Hits	227	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

RERE_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.053307 (rank : 64)
Query Neighborhood Hits	227	Target Neighborhood Hits	779	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

TAF6_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.059510 (rank : 55)
Query Neighborhood Hits	227	Target Neighborhood Hits	127	Shared Neighborhood Hits	20
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

AUXI_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.026801 (rank : 124)
Query Neighborhood Hits	227	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

DOT1L_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.063880 (rank : 51)
Query Neighborhood Hits	227	Target Neighborhood Hits	660	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DVL2_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.022600 (rank : 135)
Query Neighborhood Hits	227	Target Neighborhood Hits	223	Shared Neighborhood Hits	11
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

GLI1_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.003411 (rank : 220)
Query Neighborhood Hits	227	Target Neighborhood Hits	785	Shared Neighborhood Hits	20
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

HCN4_HUMAN
θ value	0.62314 (rank : 74)	NC score	0.020770 (rank : 139)
Query Neighborhood Hits	227	Target Neighborhood Hits	303	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HEAT3_MOUSE
θ value	0.62314 (rank : 75)	NC score	0.081743 (rank : 40)
Query Neighborhood Hits	227	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BQM4, Q8C731	Gene names	Heatr3
Domain Architecture
Description	HEAT repeat-containing protein 3.

MLL3_MOUSE
θ value	0.62314 (rank : 76)	NC score	0.045318 (rank : 74)
Query Neighborhood Hits	227	Target Neighborhood Hits	1399	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SIX5_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.025109 (rank : 129)
Query Neighborhood Hits	227	Target Neighborhood Hits	354	Shared Neighborhood Hits	26
SwissProt Accessions	P70178	Gene names	Six5, Dmahp
Domain Architecture
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog).

IMA1_HUMAN
θ value	0.813845 (rank : 78)	NC score	0.115003 (rank : 31)
Query Neighborhood Hits	227	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
θ value	0.813845 (rank : 79)	NC score	0.114669 (rank : 32)
Query Neighborhood Hits	227	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

NFRKB_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.050025 (rank : 68)
Query Neighborhood Hits	227	Target Neighborhood Hits	211	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PO2F1_MOUSE
θ value	0.813845 (rank : 81)	NC score	0.017266 (rank : 155)
Query Neighborhood Hits	227	Target Neighborhood Hits	408	Shared Neighborhood Hits	20
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

RUSC2_MOUSE
θ value	0.813845 (rank : 82)	NC score	0.041830 (rank : 87)
Query Neighborhood Hits	227	Target Neighborhood Hits	305	Shared Neighborhood Hits	35
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SRRM2_HUMAN
θ value	0.813845 (rank : 83)	NC score	0.065156 (rank : 50)
Query Neighborhood Hits	227	Target Neighborhood Hits	1296	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CBP_HUMAN
θ value	1.06291 (rank : 84)	NC score	0.042481 (rank : 83)
Query Neighborhood Hits	227	Target Neighborhood Hits	941	Shared Neighborhood Hits	84
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

F100B_MOUSE
θ value	1.06291 (rank : 85)	NC score	0.031900 (rank : 108)
Query Neighborhood Hits	227	Target Neighborhood Hits	91	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

FOXI1_MOUSE
θ value	1.06291 (rank : 86)	NC score	0.011095 (rank : 181)
Query Neighborhood Hits	227	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q922I5, Q5SRI5, Q9D299	Gene names	Foxi1
Domain Architecture	No domain graphic available
Description	Forkhead box protein I1.

IQEC2_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.028723 (rank : 118)
Query Neighborhood Hits	227	Target Neighborhood Hits	403	Shared Neighborhood Hits	35
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	1.06291 (rank : 88)	NC score	0.028836 (rank : 117)
Query Neighborhood Hits	227	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

MAST4_HUMAN
θ value	1.06291 (rank : 89)	NC score	0.013893 (rank : 164)
Query Neighborhood Hits	227	Target Neighborhood Hits	1804	Shared Neighborhood Hits	93
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MUC2_HUMAN
θ value	1.06291 (rank : 90)	NC score	0.039103 (rank : 92)
Query Neighborhood Hits	227	Target Neighborhood Hits	906	Shared Neighborhood Hits	64
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

RIN3_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.039683 (rank : 90)
Query Neighborhood Hits	227	Target Neighborhood Hits	227	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SHAN1_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.023502 (rank : 133)
Query Neighborhood Hits	227	Target Neighborhood Hits	1041	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR40_MOUSE
θ value	1.38821 (rank : 93)	NC score	0.031039 (rank : 109)
Query Neighborhood Hits	227	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

BAIP2_HUMAN
θ value	1.38821 (rank : 94)	NC score	0.032886 (rank : 105)
Query Neighborhood Hits	227	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BRCA2_HUMAN
θ value	1.38821 (rank : 95)	NC score	0.023932 (rank : 132)
Query Neighborhood Hits	227	Target Neighborhood Hits	202	Shared Neighborhood Hits	10
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CABIN_HUMAN
θ value	1.38821 (rank : 96)	NC score	0.050143 (rank : 67)
Query Neighborhood Hits	227	Target Neighborhood Hits	490	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CIC_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.037824 (rank : 94)
Query Neighborhood Hits	227	Target Neighborhood Hits	992	Shared Neighborhood Hits	78
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

COIA1_HUMAN
θ value	1.38821 (rank : 98)	NC score	0.020679 (rank : 140)
Query Neighborhood Hits	227	Target Neighborhood Hits	447	Shared Neighborhood Hits	37
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

K2002_MOUSE
θ value	1.38821 (rank : 99)	NC score	0.025505 (rank : 127)
Query Neighborhood Hits	227	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

MAML1_MOUSE
θ value	1.38821 (rank : 100)	NC score	0.044839 (rank : 75)
Query Neighborhood Hits	227	Target Neighborhood Hits	279	Shared Neighborhood Hits	38
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

NRAM2_HUMAN
θ value	1.38821 (rank : 101)	NC score	0.026925 (rank : 123)
Query Neighborhood Hits	227	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P49281, O43288, O60932, Q96J35	Gene names	SLC11A2, NRAMP2
Domain Architecture
Description	Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent metal transporter 1) (DMT1).

PARM1_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.058224 (rank : 58)
Query Neighborhood Hits	227	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

SMBP2_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.015361 (rank : 160)
Query Neighborhood Hits	227	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

TTP_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.041895 (rank : 86)
Query Neighborhood Hits	227	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

ZIMP7_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.030203 (rank : 112)
Query Neighborhood Hits	227	Target Neighborhood Hits	566	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ATX2L_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.039579 (rank : 91)
Query Neighborhood Hits	227	Target Neighborhood Hits	443	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CD248_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.019299 (rank : 149)
Query Neighborhood Hits	227	Target Neighborhood Hits	679	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

HEAT3_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.056685 (rank : 61)
Query Neighborhood Hits	227	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4Q2, Q8N525, Q8WV56, Q96CC9, Q9NWN7	Gene names	HEATR3
Domain Architecture
Description	HEAT repeat-containing protein 3.

HMMR_MOUSE
θ value	1.81305 (rank : 109)	NC score	0.011309 (rank : 178)
Query Neighborhood Hits	227	Target Neighborhood Hits	1178	Shared Neighborhood Hits	23
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

IMA4_HUMAN
θ value	1.81305 (rank : 110)	NC score	0.124903 (rank : 27)
Query Neighborhood Hits	227	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
θ value	1.81305 (rank : 111)	NC score	0.124678 (rank : 28)
Query Neighborhood Hits	227	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

MBD5_HUMAN
θ value	1.81305 (rank : 112)	NC score	0.042534 (rank : 82)
Query Neighborhood Hits	227	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

NCOA6_HUMAN
θ value	1.81305 (rank : 113)	NC score	0.058718 (rank : 56)
Query Neighborhood Hits	227	Target Neighborhood Hits	1202	Shared Neighborhood Hits	108
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PHF12_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.017892 (rank : 153)
Query Neighborhood Hits	227	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PO6F1_MOUSE
θ value	1.81305 (rank : 115)	NC score	0.013674 (rank : 166)
Query Neighborhood Hits	227	Target Neighborhood Hits	581	Shared Neighborhood Hits	40
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

RD23A_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.023300 (rank : 134)
Query Neighborhood Hits	227	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

RTN4_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.024919 (rank : 131)
Query Neighborhood Hits	227	Target Neighborhood Hits	357	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SNPC4_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.038088 (rank : 93)
Query Neighborhood Hits	227	Target Neighborhood Hits	589	Shared Neighborhood Hits	58
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SRRM1_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.050494 (rank : 66)
Query Neighborhood Hits	227	Target Neighborhood Hits	690	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

T240L_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.026748 (rank : 125)
Query Neighborhood Hits	227	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

ULK2_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.008058 (rank : 195)
Query Neighborhood Hits	227	Target Neighborhood Hits	979	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

ZO1_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.012538 (rank : 172)
Query Neighborhood Hits	227	Target Neighborhood Hits	474	Shared Neighborhood Hits	35
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CDSN_MOUSE
θ value	2.36792 (rank : 123)	NC score	0.030849 (rank : 110)
Query Neighborhood Hits	227	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

GSCR1_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.056601 (rank : 62)
Query Neighborhood Hits	227	Target Neighborhood Hits	674	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

K0999_MOUSE
θ value	2.36792 (rank : 125)	NC score	0.008164 (rank : 194)
Query Neighborhood Hits	227	Target Neighborhood Hits	931	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

KLF12_MOUSE
θ value	2.36792 (rank : 126)	NC score	0.004158 (rank : 216)
Query Neighborhood Hits	227	Target Neighborhood Hits	721	Shared Neighborhood Hits	19
SwissProt Accessions	O35738	Gene names	Klf12, Ap2rep
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

MUC1_HUMAN
θ value	2.36792 (rank : 127)	NC score	0.062070 (rank : 53)
Query Neighborhood Hits	227	Target Neighborhood Hits	975	Shared Neighborhood Hits	103
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_MOUSE
θ value	2.36792 (rank : 128)	NC score	0.062646 (rank : 52)
Query Neighborhood Hits	227	Target Neighborhood Hits	1076	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NELFA_MOUSE
θ value	2.36792 (rank : 129)	NC score	0.058240 (rank : 57)
Query Neighborhood Hits	227	Target Neighborhood Hits	195	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NFAC3_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.013886 (rank : 165)
Query Neighborhood Hits	227	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

NFAT5_MOUSE
θ value	2.36792 (rank : 131)	NC score	0.019498 (rank : 147)
Query Neighborhood Hits	227	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

OBSCN_HUMAN
θ value	2.36792 (rank : 132)	NC score	0.006483 (rank : 203)
Query Neighborhood Hits	227	Target Neighborhood Hits	1931	Shared Neighborhood Hits	63
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

RARA_MOUSE
θ value	2.36792 (rank : 133)	NC score	0.004579 (rank : 213)
Query Neighborhood Hits	227	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

SNIP_MOUSE
θ value	2.36792 (rank : 134)	NC score	0.019801 (rank : 145)
Query Neighborhood Hits	227	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SP5_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.003330 (rank : 222)
Query Neighborhood Hits	227	Target Neighborhood Hits	832	Shared Neighborhood Hits	25
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SP5_MOUSE
θ value	2.36792 (rank : 136)	NC score	0.003333 (rank : 221)
Query Neighborhood Hits	227	Target Neighborhood Hits	821	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

T53I2_MOUSE
θ value	2.36792 (rank : 137)	NC score	0.029070 (rank : 116)
Query Neighborhood Hits	227	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CFU8, Q711P5, Q8CHM4	Gene names	Tp53inp2, Dor, Trp53inp2
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity- regulated protein).

TCF8_MOUSE
θ value	2.36792 (rank : 138)	NC score	0.000936 (rank : 228)
Query Neighborhood Hits	227	Target Neighborhood Hits	1067	Shared Neighborhood Hits	23
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

WNK1_HUMAN
θ value	2.36792 (rank : 139)	NC score	0.012740 (rank : 170)
Query Neighborhood Hits	227	Target Neighborhood Hits	1158	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

AATK_MOUSE
θ value	3.0926 (rank : 140)	NC score	0.004679 (rank : 211)
Query Neighborhood Hits	227	Target Neighborhood Hits	942	Shared Neighborhood Hits	42
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ANKS6_MOUSE
θ value	3.0926 (rank : 141)	NC score	0.014878 (rank : 161)
Query Neighborhood Hits	227	Target Neighborhood Hits	435	Shared Neighborhood Hits	20
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR40_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.035931 (rank : 97)
Query Neighborhood Hits	227	Target Neighborhood Hits	224	Shared Neighborhood Hits	17
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

BRD2_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.009846 (rank : 190)
Query Neighborhood Hits	227	Target Neighborhood Hits	242	Shared Neighborhood Hits	12
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

CT032_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.021838 (rank : 136)
Query Neighborhood Hits	227	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DCAK1_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.003317 (rank : 223)
Query Neighborhood Hits	227	Target Neighborhood Hits	867	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

F122A_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.033671 (rank : 101)
Query Neighborhood Hits	227	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q96E09	Gene names	FAM122A, C9orf42
Domain Architecture	No domain graphic available
Description	Protein FAM122A.

HCN1_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.016491 (rank : 157)
Query Neighborhood Hits	227	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

INP5E_HUMAN
θ value	3.0926 (rank : 148)	NC score	0.021251 (rank : 137)
Query Neighborhood Hits	227	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

MAML1_HUMAN
θ value	3.0926 (rank : 149)	NC score	0.033572 (rank : 102)
Query Neighborhood Hits	227	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MCR_HUMAN
θ value	3.0926 (rank : 150)	NC score	0.010969 (rank : 183)
Query Neighborhood Hits	227	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

MEF2C_MOUSE
θ value	3.0926 (rank : 151)	NC score	0.013446 (rank : 167)
Query Neighborhood Hits	227	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20	Gene names	Mef2c
Domain Architecture	No domain graphic available
Description	Myocyte-specific enhancer factor 2C.

NCOR2_HUMAN
θ value	3.0926 (rank : 152)	NC score	0.027212 (rank : 122)
Query Neighborhood Hits	227	Target Neighborhood Hits	870	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NOLC1_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.033298 (rank : 104)
Query Neighborhood Hits	227	Target Neighborhood Hits	452	Shared Neighborhood Hits	29
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PAIP1_HUMAN
θ value	3.0926 (rank : 154)	NC score	0.027242 (rank : 121)
Query Neighborhood Hits	227	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

RP3A_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.007980 (rank : 196)
Query Neighborhood Hits	227	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SSH2_HUMAN
θ value	3.0926 (rank : 156)	NC score	0.008605 (rank : 192)
Query Neighborhood Hits	227	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

STK3_MOUSE
θ value	3.0926 (rank : 157)	NC score	0.002572 (rank : 225)
Query Neighborhood Hits	227	Target Neighborhood Hits	869	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

ARI1A_HUMAN
θ value	4.03905 (rank : 158)	NC score	0.042118 (rank : 84)
Query Neighborhood Hits	227	Target Neighborhood Hits	787	Shared Neighborhood Hits	73
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CD2L5_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.004069 (rank : 217)
Query Neighborhood Hits	227	Target Neighborhood Hits	987	Shared Neighborhood Hits	25
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

HGS_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.019334 (rank : 148)
Query Neighborhood Hits	227	Target Neighborhood Hits	517	Shared Neighborhood Hits	30
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

KLF12_HUMAN
θ value	4.03905 (rank : 161)	NC score	0.004230 (rank : 215)
Query Neighborhood Hits	227	Target Neighborhood Hits	717	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4X4, Q5VZM7, Q9UHZ0	Gene names	KLF12, AP2REP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

MILK1_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.032001 (rank : 107)
Query Neighborhood Hits	227	Target Neighborhood Hits	788	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MSH3_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.007737 (rank : 199)
Query Neighborhood Hits	227	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

PHC3_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.030599 (rank : 111)
Query Neighborhood Hits	227	Target Neighborhood Hits	194	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

RARA_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.004018 (rank : 218)
Query Neighborhood Hits	227	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RP1L1_HUMAN
θ value	4.03905 (rank : 166)	NC score	0.025079 (rank : 130)
Query Neighborhood Hits	227	Target Neighborhood Hits	1072	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TACC2_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.011757 (rank : 176)
Query Neighborhood Hits	227	Target Neighborhood Hits	856	Shared Neighborhood Hits	42
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

ABL1_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.002312 (rank : 226)
Query Neighborhood Hits	227	Target Neighborhood Hits	1178	Shared Neighborhood Hits	40
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

AP180_MOUSE
θ value	5.27518 (rank : 169)	NC score	0.020181 (rank : 142)
Query Neighborhood Hits	227	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

BAP1_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.028612 (rank : 120)
Query Neighborhood Hits	227	Target Neighborhood Hits	106	Shared Neighborhood Hits	19
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

BAP1_MOUSE
θ value	5.27518 (rank : 171)	NC score	0.019074 (rank : 151)
Query Neighborhood Hits	227	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

BCL3_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.005215 (rank : 209)
Query Neighborhood Hits	227	Target Neighborhood Hits	324	Shared Neighborhood Hits	13
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

BCL3_MOUSE
θ value	5.27518 (rank : 173)	NC score	0.005248 (rank : 208)
Query Neighborhood Hits	227	Target Neighborhood Hits	388	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CBP_MOUSE
θ value	5.27518 (rank : 174)	NC score	0.047057 (rank : 70)
Query Neighborhood Hits	227	Target Neighborhood Hits	1051	Shared Neighborhood Hits	97
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DOK3_HUMAN
θ value	5.27518 (rank : 175)	NC score	0.012828 (rank : 169)
Query Neighborhood Hits	227	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

F122A_MOUSE
θ value	5.27518 (rank : 176)	NC score	0.028719 (rank : 119)
Query Neighborhood Hits	227	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DB52, Q3TA50, Q9D078	Gene names	Fam122a
Domain Architecture	No domain graphic available
Description	Protein FAM122A.

FBX34_MOUSE
θ value	5.27518 (rank : 177)	NC score	0.013320 (rank : 168)
Query Neighborhood Hits	227	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

IRS1_MOUSE
θ value	5.27518 (rank : 178)	NC score	0.011476 (rank : 177)
Query Neighborhood Hits	227	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

K1802_MOUSE
θ value	5.27518 (rank : 179)	NC score	0.033314 (rank : 103)
Query Neighborhood Hits	227	Target Neighborhood Hits	1596	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NRAM2_MOUSE
θ value	5.27518 (rank : 180)	NC score	0.019713 (rank : 146)
Query Neighborhood Hits	227	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P49282, O54903	Gene names	Slc11a2, Nramp2
Domain Architecture
Description	Natural resistance-associated macrophage protein 2 (NRAMP 2).

NUP62_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.015979 (rank : 159)
Query Neighborhood Hits	227	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

OGG1_HUMAN
θ value	5.27518 (rank : 182)	NC score	0.019232 (rank : 150)
Query Neighborhood Hits	227	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O15527, O00390, O00670, O00705, O14876, O95488, P78554, Q9UIK0, Q9UIK1, Q9UIK2, Q9UL34, Q9Y2C0, Q9Y2C1, Q9Y6C3, Q9Y6C4	Gene names	OGG1, MMH, MUTM, OGH1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

PRRT3_HUMAN
θ value	5.27518 (rank : 183)	NC score	0.040115 (rank : 88)
Query Neighborhood Hits	227	Target Neighborhood Hits	998	Shared Neighborhood Hits	86
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RERE_MOUSE
θ value	5.27518 (rank : 184)	NC score	0.051925 (rank : 65)
Query Neighborhood Hits	227	Target Neighborhood Hits	785	Shared Neighborhood Hits	66
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SC24C_HUMAN
θ value	5.27518 (rank : 185)	NC score	0.039920 (rank : 89)
Query Neighborhood Hits	227	Target Neighborhood Hits	662	Shared Neighborhood Hits	68
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TM108_HUMAN
θ value	5.27518 (rank : 186)	NC score	0.029229 (rank : 115)
Query Neighborhood Hits	227	Target Neighborhood Hits	166	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

WASF3_MOUSE
θ value	5.27518 (rank : 187)	NC score	0.020080 (rank : 143)
Query Neighborhood Hits	227	Target Neighborhood Hits	188	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WNK1_MOUSE
θ value	5.27518 (rank : 188)	NC score	0.011191 (rank : 180)
Query Neighborhood Hits	227	Target Neighborhood Hits	1179	Shared Neighborhood Hits	65
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ARHG8_MOUSE
θ value	6.88961 (rank : 189)	NC score	0.009756 (rank : 191)
Query Neighborhood Hits	227	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARNT2_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.007971 (rank : 197)
Query Neighborhood Hits	227	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

BTAF1_HUMAN
θ value	6.88961 (rank : 191)	NC score	0.006109 (rank : 205)
Query Neighborhood Hits	227	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

FANCM_MOUSE
θ value	6.88961 (rank : 192)	NC score	0.010817 (rank : 185)
Query Neighborhood Hits	227	Target Neighborhood Hits	177	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

FOXE2_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.007547 (rank : 200)
Query Neighborhood Hits	227	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

FREA_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.006159 (rank : 204)
Query Neighborhood Hits	227	Target Neighborhood Hits	205	Shared Neighborhood Hits	22
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

HXD4_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.003882 (rank : 219)
Query Neighborhood Hits	227	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	P09016, Q96AU0	Gene names	HOXD4, HOX4B
Domain Architecture
Description	Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13).

KMHN1_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.004666 (rank : 212)
Query Neighborhood Hits	227	Target Neighborhood Hits	950	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

LATS1_HUMAN
θ value	6.88961 (rank : 197)	NC score	0.004269 (rank : 214)
Query Neighborhood Hits	227	Target Neighborhood Hits	1057	Shared Neighborhood Hits	41
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

LDB3_MOUSE
θ value	6.88961 (rank : 198)	NC score	0.016885 (rank : 156)
Query Neighborhood Hits	227	Target Neighborhood Hits	510	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MARCS_HUMAN
θ value	6.88961 (rank : 199)	NC score	0.041982 (rank : 85)
Query Neighborhood Hits	227	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MDC1_HUMAN
θ value	6.88961 (rank : 200)	NC score	0.047279 (rank : 69)
Query Neighborhood Hits	227	Target Neighborhood Hits	1446	Shared Neighborhood Hits	98
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MEF2C_HUMAN
θ value	6.88961 (rank : 201)	NC score	0.012393 (rank : 173)
Query Neighborhood Hits	227	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

NKRF_MOUSE
θ value	6.88961 (rank : 202)	NC score	0.014056 (rank : 163)
Query Neighborhood Hits	227	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BY02, Q8BJU5, Q9CRL2	Gene names	Nkrf, Nrf
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF).

NUP53_MOUSE
θ value	6.88961 (rank : 203)	NC score	0.018950 (rank : 152)
Query Neighborhood Hits	227	Target Neighborhood Hits	94	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

P66B_HUMAN
θ value	6.88961 (rank : 204)	NC score	0.014196 (rank : 162)
Query Neighborhood Hits	227	Target Neighborhood Hits	61	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXI9, Q7LG68, Q9ULS0	Gene names	GATAD2B, KIAA1150
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

PHC3_HUMAN
θ value	6.88961 (rank : 205)	NC score	0.025739 (rank : 126)
Query Neighborhood Hits	227	Target Neighborhood Hits	218	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PKNX2_MOUSE
θ value	6.88961 (rank : 206)	NC score	0.006025 (rank : 206)
Query Neighborhood Hits	227	Target Neighborhood Hits	197	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

SFPQ_HUMAN
θ value	6.88961 (rank : 207)	NC score	0.025435 (rank : 128)
Query Neighborhood Hits	227	Target Neighborhood Hits	986	Shared Neighborhood Hits	60
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SPEG_HUMAN
θ value	6.88961 (rank : 208)	NC score	0.007844 (rank : 198)
Query Neighborhood Hits	227	Target Neighborhood Hits	1762	Shared Neighborhood Hits	74
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

T53I2_HUMAN
θ value	6.88961 (rank : 209)	NC score	0.017600 (rank : 154)
Query Neighborhood Hits	227	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IXH6, Q5JX64, Q8IYL5, Q9NU00	Gene names	TP53INP2, C20orf110, PINH
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (p53-inducible protein U) (PIG-U).

TMPSD_MOUSE
θ value	6.88961 (rank : 210)	NC score	0.004890 (rank : 210)
Query Neighborhood Hits	227	Target Neighborhood Hits	334	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TULP4_MOUSE
θ value	6.88961 (rank : 211)	NC score	0.012079 (rank : 175)
Query Neighborhood Hits	227	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

XRCC1_MOUSE
θ value	6.88961 (rank : 212)	NC score	0.010176 (rank : 186)
Query Neighborhood Hits	227	Target Neighborhood Hits	242	Shared Neighborhood Hits	12
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

A2BP1_MOUSE
θ value	8.99809 (rank : 213)	NC score	0.006529 (rank : 202)
Query Neighborhood Hits	227	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJ43, Q9JJB5	Gene names	A2bp1, A2bp
Domain Architecture
Description	Ataxin-2-binding protein 1.

ARHG8_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.008473 (rank : 193)
Query Neighborhood Hits	227	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

CABL2_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.006901 (rank : 201)
Query Neighborhood Hits	227	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CT2NL_MOUSE
θ value	8.99809 (rank : 216)	NC score	0.011009 (rank : 182)
Query Neighborhood Hits	227	Target Neighborhood Hits	902	Shared Neighborhood Hits	32
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DMD_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.002629 (rank : 224)
Query Neighborhood Hits	227	Target Neighborhood Hits	1135	Shared Neighborhood Hits	18
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

F120A_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.010951 (rank : 184)
Query Neighborhood Hits	227	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZB2, O60649, Q14688, Q4VXF4, Q4VXF5, Q4VXG2, Q96I21, Q9NZB1	Gene names	FAM120A, C9orf10, KIAA0183
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120A.

NFRKB_MOUSE
θ value	8.99809 (rank : 219)	NC score	0.057016 (rank : 59)
Query Neighborhood Hits	227	Target Neighborhood Hits	393	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NUP53_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.020025 (rank : 144)
Query Neighborhood Hits	227	Target Neighborhood Hits	156	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

PAG1_MOUSE
θ value	8.99809 (rank : 221)	NC score	0.012692 (rank : 171)
Query Neighborhood Hits	227	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U1F9, Q8BFS1, Q9EQF3	Gene names	Pag1, Cbp, Pag
Domain Architecture	No domain graphic available
Description	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp).

PAK6_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.001847 (rank : 227)
Query Neighborhood Hits	227	Target Neighborhood Hits	915	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

PCX3_MOUSE
θ value	8.99809 (rank : 223)	NC score	0.010014 (rank : 188)
Query Neighborhood Hits	227	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

REPS2_MOUSE
θ value	8.99809 (rank : 224)	NC score	0.009907 (rank : 189)
Query Neighborhood Hits	227	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

RFC1_HUMAN
θ value	8.99809 (rank : 225)	NC score	0.016407 (rank : 158)
Query Neighborhood Hits	227	Target Neighborhood Hits	352	Shared Neighborhood Hits	15
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

SP4_MOUSE
θ value	8.99809 (rank : 226)	NC score	-0.000280 (rank : 229)
Query Neighborhood Hits	227	Target Neighborhood Hits	759	Shared Neighborhood Hits	17
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

TGON2_HUMAN
θ value	8.99809 (rank : 227)	NC score	0.035364 (rank : 99)
Query Neighborhood Hits	227	Target Neighborhood Hits	1037	Shared Neighborhood Hits	77
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

MUC7_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.067287 (rank : 48)
Query Neighborhood Hits	227	Target Neighborhood Hits	538	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

SPAG6_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.053749 (rank : 63)
Query Neighborhood Hits	227	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

Hits sorted by NC score

CTND2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	227	Target Neighborhood Hits	227	Shared Neighborhood Hits	227
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.985263 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	227	Target Neighborhood Hits	333	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PKP4_HUMAN
NC score	0.964321 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	227	Target Neighborhood Hits	107	Shared Neighborhood Hits	45
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP4_MOUSE
NC score	0.964230 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	227	Target Neighborhood Hits	129	Shared Neighborhood Hits	49
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

ARVC_MOUSE
NC score	0.938610 (rank : 5)	θ value	3.28708e-135 (rank : 5)
Query Neighborhood Hits	227	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

ARVC_HUMAN
NC score	0.936130 (rank : 6)	θ value	2.78268e-134 (rank : 6)
Query Neighborhood Hits	227	Target Neighborhood Hits	95	Shared Neighborhood Hits	36
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

CTND1_MOUSE
NC score	0.932436 (rank : 7)	θ value	5.61992e-127 (rank : 8)
Query Neighborhood Hits	227	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
NC score	0.931167 (rank : 8)	θ value	8.67031e-128 (rank : 7)
Query Neighborhood Hits	227	Target Neighborhood Hits	67	Shared Neighborhood Hits	32
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

PKP2_HUMAN
NC score	0.894331 (rank : 9)	θ value	1.04338e-64 (rank : 10)
Query Neighborhood Hits	227	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PKP1_MOUSE
NC score	0.888669 (rank : 10)	θ value	5.00389e-67 (rank : 9)
Query Neighborhood Hits	227	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP3_HUMAN
NC score	0.886555 (rank : 11)	θ value	2.17557e-62 (rank : 12)
Query Neighborhood Hits	227	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP1_HUMAN
NC score	0.886419 (rank : 12)	θ value	5.17823e-64 (rank : 11)
Query Neighborhood Hits	227	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP3_MOUSE
NC score	0.884846 (rank : 13)	θ value	3.47335e-60 (rank : 13)
Query Neighborhood Hits	227	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

ARMC4_HUMAN
NC score	0.370310 (rank : 14)	θ value	0.00228821 (rank : 22)
Query Neighborhood Hits	227	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_MOUSE
NC score	0.300490 (rank : 15)	θ value	1.09739e-05 (rank : 16)
Query Neighborhood Hits	227	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.300423 (rank : 16)	θ value	1.09739e-05 (rank : 15)
Query Neighborhood Hits	227	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.273574 (rank : 17)	θ value	4.92598e-06 (rank : 14)
Query Neighborhood Hits	227	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

APC_MOUSE
NC score	0.244795 (rank : 18)	θ value	2.44474e-05 (rank : 17)
Query Neighborhood Hits	227	Target Neighborhood Hits	441	Shared Neighborhood Hits	50
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.241743 (rank : 19)	θ value	3.19293e-05 (rank : 18)
Query Neighborhood Hits	227	Target Neighborhood Hits	603	Shared Neighborhood Hits	64
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PLAK_HUMAN
NC score	0.234224 (rank : 20)	θ value	0.00390308 (rank : 25)
Query Neighborhood Hits	227	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

GDS1_HUMAN
NC score	0.193781 (rank : 21)	θ value	0.00665767 (rank : 27)
Query Neighborhood Hits	227	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

IMA7_MOUSE
NC score	0.155399 (rank : 22)	θ value	0.000461057 (rank : 20)
Query Neighborhood Hits	227	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA7_HUMAN
NC score	0.150889 (rank : 23)	θ value	0.00134147 (rank : 21)
Query Neighborhood Hits	227	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA5_HUMAN
NC score	0.145260 (rank : 24)	θ value	0.0193708 (rank : 29)
Query Neighborhood Hits	227	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA2_MOUSE
NC score	0.135700 (rank : 25)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	227	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA2_HUMAN
NC score	0.134990 (rank : 26)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	227	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA4_HUMAN
NC score	0.124903 (rank : 27)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	227	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
NC score	0.124678 (rank : 28)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	227	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA3_MOUSE
NC score	0.119934 (rank : 29)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	227	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
NC score	0.119753 (rank : 30)	θ value	0.365318 (rank : 59)
Query Neighborhood Hits	227	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA1_HUMAN
NC score	0.115003 (rank : 31)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	227	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
NC score	0.114669 (rank : 32)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	227	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

ATN1_HUMAN
NC score	0.109517 (rank : 33)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	227	Target Neighborhood Hits	676	Shared Neighborhood Hits	69
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

PARM1_MOUSE
NC score	0.104800 (rank : 34)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	227	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

MUC13_MOUSE
NC score	0.099454 (rank : 35)	θ value	4.1701e-05 (rank : 19)
Query Neighborhood Hits	227	Target Neighborhood Hits	447	Shared Neighborhood Hits	36
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

CK024_HUMAN
NC score	0.097431 (rank : 36)	θ value	0.00869519 (rank : 28)
Query Neighborhood Hits	227	Target Neighborhood Hits	408	Shared Neighborhood Hits	55
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SRRM2_MOUSE
NC score	0.087818 (rank : 37)	θ value	0.00509761 (rank : 26)
Query Neighborhood Hits	227	Target Neighborhood Hits	1470	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

T22D2_HUMAN
NC score	0.085781 (rank : 38)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	227	Target Neighborhood Hits	250	Shared Neighborhood Hits	41
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

NACAM_MOUSE
NC score	0.084982 (rank : 39)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	227	Target Neighborhood Hits	1866	Shared Neighborhood Hits	131
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

HEAT3_MOUSE
NC score	0.081743 (rank : 40)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	227	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BQM4, Q8C731	Gene names	Heatr3
Domain Architecture
Description	HEAT repeat-containing protein 3.

BSN_MOUSE
NC score	0.078955 (rank : 41)	θ value	0.00228821 (rank : 23)
Query Neighborhood Hits	227	Target Neighborhood Hits	2057	Shared Neighborhood Hits	132
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MUC1_MOUSE
NC score	0.078185 (rank : 42)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	227	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

TAF6_MOUSE
NC score	0.075472 (rank : 43)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	227	Target Neighborhood Hits	110	Shared Neighborhood Hits	21
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

NELFA_HUMAN
NC score	0.072741 (rank : 44)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	227	Target Neighborhood Hits	161	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

RPB1_MOUSE
NC score	0.069910 (rank : 45)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	227	Target Neighborhood Hits	363	Shared Neighborhood Hits	42
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.069767 (rank : 46)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	227	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ZCH14_HUMAN
NC score	0.068652 (rank : 47)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	227	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

MUC7_HUMAN
NC score	0.067287 (rank : 48)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	227	Target Neighborhood Hits	538	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

EWS_HUMAN
NC score	0.065609 (rank : 49)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	227	Target Neighborhood Hits	249	Shared Neighborhood Hits	21
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

SRRM2_HUMAN
NC score	0.065156 (rank : 50)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	227	Target Neighborhood Hits	1296	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DOT1L_HUMAN
NC score	0.063880 (rank : 51)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	227	Target Neighborhood Hits	660	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

NCOA6_MOUSE
NC score	0.062646 (rank : 52)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	227	Target Neighborhood Hits	1076	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MUC1_HUMAN
NC score	0.062070 (rank : 53)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	227	Target Neighborhood Hits	975	Shared Neighborhood Hits	103
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

BSN_HUMAN
NC score	0.060286 (rank : 54)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	227	Target Neighborhood Hits	1537	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

TAF6_HUMAN
NC score	0.059510 (rank : 55)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	227	Target Neighborhood Hits	127	Shared Neighborhood Hits	20
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

NCOA6_HUMAN
NC score	0.058718 (rank : 56)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	227	Target Neighborhood Hits	1202	Shared Neighborhood Hits	108
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NELFA_MOUSE
NC score	0.058240 (rank : 57)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	227	Target Neighborhood Hits	195	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

PARM1_HUMAN
NC score	0.058224 (rank : 58)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	227	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

NFRKB_MOUSE
NC score	0.057016 (rank : 59)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	227	Target Neighborhood Hits	393	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

EWS_MOUSE
NC score	0.056886 (rank : 60)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	227	Target Neighborhood Hits	271	Shared Neighborhood Hits	22
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

HEAT3_HUMAN
NC score	0.056685 (rank : 61)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	227	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4Q2, Q8N525, Q8WV56, Q96CC9, Q9NWN7	Gene names	HEATR3
Domain Architecture
Description	HEAT repeat-containing protein 3.

GSCR1_HUMAN
NC score	0.056601 (rank : 62)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	227	Target Neighborhood Hits	674	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SPAG6_HUMAN
NC score	0.053749 (rank : 63)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	227	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

RERE_HUMAN
NC score	0.053307 (rank : 64)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	227	Target Neighborhood Hits	779	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
NC score	0.051925 (rank : 65)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	227	Target Neighborhood Hits	785	Shared Neighborhood Hits	66
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SRRM1_HUMAN
NC score	0.050494 (rank : 66)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	227	Target Neighborhood Hits	690	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CABIN_HUMAN
NC score	0.050143 (rank : 67)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	227	Target Neighborhood Hits	490	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

NFRKB_HUMAN
NC score	0.050025 (rank : 68)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	227	Target Neighborhood Hits	211	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

MDC1_HUMAN
NC score	0.047279 (rank : 69)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	227	Target Neighborhood Hits	1446	Shared Neighborhood Hits	98
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CBP_MOUSE
NC score	0.047057 (rank : 70)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	227	Target Neighborhood Hits	1051	Shared Neighborhood Hits	97
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MINT_HUMAN
NC score	0.046313 (rank : 71)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	227	Target Neighborhood Hits	1291	Shared Neighborhood Hits	83
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PHLB1_MOUSE
NC score	0.046142 (rank : 72)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	227	Target Neighborhood Hits	678	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MLL3_HUMAN
NC score	0.046090 (rank : 73)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	227	Target Neighborhood Hits	1644	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
NC score	0.045318 (rank : 74)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	227	Target Neighborhood Hits	1399	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MAML1_MOUSE
NC score	0.044839 (rank : 75)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	227	Target Neighborhood Hits	279	Shared Neighborhood Hits	38
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SYNJ1_HUMAN
NC score	0.044641 (rank : 76)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	227	Target Neighborhood Hits	498	Shared Neighborhood Hits	54
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PHLB1_HUMAN
NC score	0.043506 (rank : 77)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	227	Target Neighborhood Hits	1038	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

IF4G1_HUMAN
NC score	0.043240 (rank : 78)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	227	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

PER3_HUMAN
NC score	0.043160 (rank : 79)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	227	Target Neighborhood Hits	479	Shared Neighborhood Hits	61
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

EMSY_HUMAN
NC score	0.043048 (rank : 80)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	227	Target Neighborhood Hits	296	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

MTSS1_HUMAN
NC score	0.042558 (rank : 81)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	227	Target Neighborhood Hits	504	Shared Neighborhood Hits	42
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MBD5_HUMAN
NC score	0.042534 (rank : 82)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	227	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

CBP_HUMAN
NC score	0.042481 (rank : 83)	θ value	1.06291 (rank : 84)
Query Neighborhood Hits	227	Target Neighborhood Hits	941	Shared Neighborhood Hits	84
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ARI1A_HUMAN
NC score	0.042118 (rank : 84)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	227	Target Neighborhood Hits	787	Shared Neighborhood Hits	73
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

MARCS_HUMAN
NC score	0.041982 (rank : 85)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	227	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

TTP_HUMAN
NC score	0.041895 (rank : 86)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	227	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

RUSC2_MOUSE
NC score	0.041830 (rank : 87)	θ value	0.813845 (rank : 82)
Query Neighborhood Hits	227	Target Neighborhood Hits	305	Shared Neighborhood Hits	35
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

PRRT3_HUMAN
NC score	0.040115 (rank : 88)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	227	Target Neighborhood Hits	998	Shared Neighborhood Hits	86
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SC24C_HUMAN
NC score	0.039920 (rank : 89)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	227	Target Neighborhood Hits	662	Shared Neighborhood Hits	68
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

RIN3_HUMAN
NC score	0.039683 (rank : 90)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	227	Target Neighborhood Hits	227	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ATX2L_HUMAN
NC score	0.039579 (rank : 91)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	227	Target Neighborhood Hits	443	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

MUC2_HUMAN
NC score	0.039103 (rank : 92)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	227	Target Neighborhood Hits	906	Shared Neighborhood Hits	64
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SNPC4_HUMAN
NC score	0.038088 (rank : 93)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	227	Target Neighborhood Hits	589	Shared Neighborhood Hits	58
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CIC_HUMAN
NC score	0.037824 (rank : 94)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	227	Target Neighborhood Hits	992	Shared Neighborhood Hits	78
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MAP1A_HUMAN
NC score	0.036555 (rank : 95)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	227	Target Neighborhood Hits	1626	Shared Neighborhood Hits	75
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NFH_MOUSE
NC score	0.036203 (rank : 96)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	227	Target Neighborhood Hits	2247	Shared Neighborhood Hits	116
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ANR40_HUMAN
NC score	0.035931 (rank : 97)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	227	Target Neighborhood Hits	224	Shared Neighborhood Hits	17
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

RBM14_MOUSE
NC score	0.035908 (rank : 98)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	227	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

TGON2_HUMAN
NC score	0.035364 (rank : 99)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	227	Target Neighborhood Hits	1037	Shared Neighborhood Hits	77
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RBM14_HUMAN
NC score	0.033774 (rank : 100)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	227	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

F122A_HUMAN
NC score	0.033671 (rank : 101)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	227	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q96E09	Gene names	FAM122A, C9orf42
Domain Architecture	No domain graphic available
Description	Protein FAM122A.

MAML1_HUMAN
NC score	0.033572 (rank : 102)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	227	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

K1802_MOUSE
NC score	0.033314 (rank : 103)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	227	Target Neighborhood Hits	1596	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NOLC1_HUMAN
NC score	0.033298 (rank : 104)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	227	Target Neighborhood Hits	452	Shared Neighborhood Hits	29
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

BAIP2_HUMAN
NC score	0.032886 (rank : 105)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	227	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

DVL2_MOUSE
NC score	0.032113 (rank : 106)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	227	Target Neighborhood Hits	233	Shared Neighborhood Hits	18
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

MILK1_MOUSE
NC score	0.032001 (rank : 107)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	227	Target Neighborhood Hits	788	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

F100B_MOUSE
NC score	0.031900 (rank : 108)	θ value	1.06291 (rank : 85)
Query Neighborhood Hits	227	Target Neighborhood Hits	91	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

ANR40_MOUSE
NC score	0.031039 (rank : 109)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	227	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CDSN_MOUSE
NC score	0.030849 (rank : 110)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	227	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

PHC3_MOUSE
NC score	0.030599 (rank : 111)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	227	Target Neighborhood Hits	194	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

ZIMP7_MOUSE
NC score	0.030203 (rank : 112)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	227	Target Neighborhood Hits	566	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

LPIN3_HUMAN
NC score	0.029959 (rank : 113)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	227	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

MAGC1_HUMAN
NC score	0.029605 (rank : 114)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	227	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

TM108_HUMAN
NC score	0.029229 (rank : 115)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	227	Target Neighborhood Hits	166	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

T53I2_MOUSE
NC score	0.029070 (rank : 116)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	227	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CFU8, Q711P5, Q8CHM4	Gene names	Tp53inp2, Dor, Trp53inp2
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity- regulated protein).

IQEC2_MOUSE
NC score	0.028836 (rank : 117)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	227	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.028723 (rank : 118)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	227	Target Neighborhood Hits	403	Shared Neighborhood Hits	35
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

F122A_MOUSE
NC score	0.028719 (rank : 119)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	227	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DB52, Q3TA50, Q9D078	Gene names	Fam122a
Domain Architecture	No domain graphic available
Description	Protein FAM122A.

BAP1_HUMAN
NC score	0.028612 (rank : 120)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	227	Target Neighborhood Hits	106	Shared Neighborhood Hits	19
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

PAIP1_HUMAN
NC score	0.027242 (rank : 121)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	227	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

NCOR2_HUMAN
NC score	0.027212 (rank : 122)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	227	Target Neighborhood Hits	870	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NRAM2_HUMAN
NC score	0.026925 (rank : 123)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	227	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P49281, O43288, O60932, Q96J35	Gene names	SLC11A2, NRAMP2
Domain Architecture
Description	Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent metal transporter 1) (DMT1).

AUXI_HUMAN
NC score	0.026801 (rank : 124)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	227	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

T240L_HUMAN
NC score	0.026748 (rank : 125)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	227	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

PHC3_HUMAN
NC score	0.025739 (rank : 126)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	227	Target Neighborhood Hits	218	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

K2002_MOUSE
NC score	0.025505 (rank : 127)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	227	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

SFPQ_HUMAN
NC score	0.025435 (rank : 128)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	227	Target Neighborhood Hits	986	Shared Neighborhood Hits	60
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SIX5_MOUSE
NC score	0.025109 (rank : 129)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	227	Target Neighborhood Hits	354	Shared Neighborhood Hits	26
SwissProt Accessions	P70178	Gene names	Six5, Dmahp
Domain Architecture
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog).

RP1L1_HUMAN
NC score	0.025079 (rank : 130)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	227	Target Neighborhood Hits	1072	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RTN4_HUMAN
NC score	0.024919 (rank : 131)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	227	Target Neighborhood Hits	357	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

BRCA2_HUMAN
NC score	0.023932 (rank : 132)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	227	Target Neighborhood Hits	202	Shared Neighborhood Hits	10
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

SHAN1_HUMAN
NC score	0.023502 (rank : 133)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	227	Target Neighborhood Hits	1041	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

RD23A_MOUSE
NC score	0.023300 (rank : 134)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	227	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

DVL2_HUMAN
NC score	0.022600 (rank : 135)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	227	Target Neighborhood Hits	223	Shared Neighborhood Hits	11
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

CT032_HUMAN
NC score	0.021838 (rank : 136)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	227	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

INP5E_HUMAN
NC score	0.021251 (rank : 137)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	227	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

CHD9_MOUSE
NC score	0.021029 (rank : 138)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	227	Target Neighborhood Hits	427	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

HCN4_HUMAN
NC score	0.020770 (rank : 139)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	227	Target Neighborhood Hits	303	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

COIA1_HUMAN
NC score	0.020679 (rank : 140)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	227	Target Neighborhood Hits	447	Shared Neighborhood Hits	37
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

ANKS6_HUMAN
NC score	0.020414 (rank : 141)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	227	Target Neighborhood Hits	411	Shared Neighborhood Hits	20
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

AP180_MOUSE
NC score	0.020181 (rank : 142)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	227	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

WASF3_MOUSE
NC score	0.020080 (rank : 143)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	227	Target Neighborhood Hits	188	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

NUP53_HUMAN
NC score	0.020025 (rank : 144)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	227	Target Neighborhood Hits	156	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

SNIP_MOUSE
NC score	0.019801 (rank : 145)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	227	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

NRAM2_MOUSE
NC score	0.019713 (rank : 146)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	227	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P49282, O54903	Gene names	Slc11a2, Nramp2
Domain Architecture
Description	Natural resistance-associated macrophage protein 2 (NRAMP 2).

NFAT5_MOUSE
NC score	0.019498 (rank : 147)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	227	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

HGS_HUMAN
NC score	0.019334 (rank : 148)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	227	Target Neighborhood Hits	517	Shared Neighborhood Hits	30
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

CD248_HUMAN
NC score	0.019299 (rank : 149)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	227	Target Neighborhood Hits	679	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

OGG1_HUMAN
NC score	0.019232 (rank : 150)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	227	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O15527, O00390, O00670, O00705, O14876, O95488, P78554, Q9UIK0, Q9UIK1, Q9UIK2, Q9UL34, Q9Y2C0, Q9Y2C1, Q9Y6C3, Q9Y6C4	Gene names	OGG1, MMH, MUTM, OGH1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

BAP1_MOUSE
NC score	0.019074 (rank : 151)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	227	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

NUP53_MOUSE
NC score	0.018950 (rank : 152)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	227	Target Neighborhood Hits	94	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

PHF12_HUMAN
NC score	0.017892 (rank : 153)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	227	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

T53I2_HUMAN
NC score	0.017600 (rank : 154)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	227	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IXH6, Q5JX64, Q8IYL5, Q9NU00	Gene names	TP53INP2, C20orf110, PINH
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (p53-inducible protein U) (PIG-U).

PO2F1_MOUSE
NC score	0.017266 (rank : 155)	θ value	0.813845 (rank : 81)
Query Neighborhood Hits	227	Target Neighborhood Hits	408	Shared Neighborhood Hits	20
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

LDB3_MOUSE
NC score	0.016885 (rank : 156)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	227	Target Neighborhood Hits	510	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

HCN1_HUMAN
NC score	0.016491 (rank : 157)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	227	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

RFC1_HUMAN
NC score	0.016407 (rank : 158)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	227	Target Neighborhood Hits	352	Shared Neighborhood Hits	15
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

NUP62_HUMAN
NC score	0.015979 (rank : 159)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	227	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

SMBP2_MOUSE
NC score	0.015361 (rank : 160)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	227	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

ANKS6_MOUSE
NC score	0.014878 (rank : 161)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	227	Target Neighborhood Hits	435	Shared Neighborhood Hits	20
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

P66B_HUMAN
NC score	0.014196 (rank : 162)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	227	Target Neighborhood Hits	61	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXI9, Q7LG68, Q9ULS0	Gene names	GATAD2B, KIAA1150
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

NKRF_MOUSE
NC score	0.014056 (rank : 163)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	227	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BY02, Q8BJU5, Q9CRL2	Gene names	Nkrf, Nrf
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF).

MAST4_HUMAN
NC score	0.013893 (rank : 164)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	227	Target Neighborhood Hits	1804	Shared Neighborhood Hits	93
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NFAC3_MOUSE
NC score	0.013886 (rank : 165)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	227	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

PO6F1_MOUSE
NC score	0.013674 (rank : 166)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	227	Target Neighborhood Hits	581	Shared Neighborhood Hits	40
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

MEF2C_MOUSE
NC score	0.013446 (rank : 167)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	227	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20	Gene names	Mef2c
Domain Architecture	No domain graphic available
Description	Myocyte-specific enhancer factor 2C.

FBX34_MOUSE
NC score	0.013320 (rank : 168)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	227	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

DOK3_HUMAN
NC score	0.012828 (rank : 169)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	227	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

WNK1_HUMAN
NC score	0.012740 (rank : 170)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	227	Target Neighborhood Hits	1158	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

PAG1_MOUSE
NC score	0.012692 (rank : 171)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	227	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U1F9, Q8BFS1, Q9EQF3	Gene names	Pag1, Cbp, Pag
Domain Architecture	No domain graphic available
Description	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp).

ZO1_HUMAN
NC score	0.012538 (rank : 172)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	227	Target Neighborhood Hits	474	Shared Neighborhood Hits	35
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

MEF2C_HUMAN
NC score	0.012393 (rank : 173)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	227	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

SALL3_HUMAN
NC score	0.012168 (rank : 174)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	227	Target Neighborhood Hits	1066	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

TULP4_MOUSE
NC score	0.012079 (rank : 175)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	227	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TACC2_HUMAN
NC score	0.011757 (rank : 176)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	227	Target Neighborhood Hits	856	Shared Neighborhood Hits	42
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

IRS1_MOUSE
NC score	0.011476 (rank : 177)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	227	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

HMMR_MOUSE
NC score	0.011309 (rank : 178)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	227	Target Neighborhood Hits	1178	Shared Neighborhood Hits	23
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GOGB1_HUMAN
NC score	0.011270 (rank : 179)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	227	Target Neighborhood Hits	2297	Shared Neighborhood Hits	50
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

WNK1_MOUSE
NC score	0.011191 (rank : 180)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	227	Target Neighborhood Hits	1179	Shared Neighborhood Hits	65
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

FOXI1_MOUSE
NC score	0.011095 (rank : 181)	θ value	1.06291 (rank : 86)
Query Neighborhood Hits	227	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q922I5, Q5SRI5, Q9D299	Gene names	Foxi1
Domain Architecture	No domain graphic available
Description	Forkhead box protein I1.

CT2NL_MOUSE
NC score	0.011009 (rank : 182)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	227	Target Neighborhood Hits	902	Shared Neighborhood Hits	32
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MCR_HUMAN
NC score	0.010969 (rank : 183)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	227	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

F120A_HUMAN
NC score	0.010951 (rank : 184)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	227	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZB2, O60649, Q14688, Q4VXF4, Q4VXF5, Q4VXG2, Q96I21, Q9NZB1	Gene names	FAM120A, C9orf10, KIAA0183
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120A.

FANCM_MOUSE
NC score	0.010817 (rank : 185)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	227	Target Neighborhood Hits	177	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

XRCC1_MOUSE
NC score	0.010176 (rank : 186)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	227	Target Neighborhood Hits	242	Shared Neighborhood Hits	12
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

K0999_HUMAN
NC score	0.010165 (rank : 187)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	227	Target Neighborhood Hits	899	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

PCX3_MOUSE
NC score	0.010014 (rank : 188)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	227	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

REPS2_MOUSE
NC score	0.009907 (rank : 189)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	227	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

BRD2_HUMAN
NC score	0.009846 (rank : 190)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	227	Target Neighborhood Hits	242	Shared Neighborhood Hits	12
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

ARHG8_MOUSE
NC score	0.009756 (rank : 191)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	227	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

SSH2_HUMAN
NC score	0.008605 (rank : 192)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	227	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

ARHG8_HUMAN
NC score	0.008473 (rank : 193)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	227	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

K0999_MOUSE
NC score	0.008164 (rank : 194)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	227	Target Neighborhood Hits	931	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

ULK2_HUMAN
NC score	0.008058 (rank : 195)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	227	Target Neighborhood Hits	979	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

RP3A_HUMAN
NC score	0.007980 (rank : 196)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	227	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

ARNT2_HUMAN
NC score	0.007971 (rank : 197)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	227	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

SPEG_HUMAN
NC score	0.007844 (rank : 198)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	227	Target Neighborhood Hits	1762	Shared Neighborhood Hits	74
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MSH3_HUMAN
NC score	0.007737 (rank : 199)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	227	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

FOXE2_HUMAN
NC score	0.007547 (rank : 200)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	227	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

CABL2_MOUSE
NC score	0.006901 (rank : 201)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	227	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

A2BP1_MOUSE
NC score	0.006529 (rank : 202)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	227	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJ43, Q9JJB5	Gene names	A2bp1, A2bp
Domain Architecture
Description	Ataxin-2-binding protein 1.

OBSCN_HUMAN
NC score	0.006483 (rank : 203)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	227	Target Neighborhood Hits	1931	Shared Neighborhood Hits	63
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

FREA_HUMAN
NC score	0.006159 (rank : 204)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	227	Target Neighborhood Hits	205	Shared Neighborhood Hits	22
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

BTAF1_HUMAN
NC score	0.006109 (rank : 205)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	227	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

PKNX2_MOUSE
NC score	0.006025 (rank : 206)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	227	Target Neighborhood Hits	197	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

STK3_HUMAN
NC score	0.005342 (rank : 207)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	227	Target Neighborhood Hits	861	Shared Neighborhood Hits	18
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

BCL3_MOUSE
NC score	0.005248 (rank : 208)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	227	Target Neighborhood Hits	388	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

BCL3_HUMAN
NC score	0.005215 (rank : 209)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	227	Target Neighborhood Hits	324	Shared Neighborhood Hits	13
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

TMPSD_MOUSE
NC score	0.004890 (rank : 210)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	227	Target Neighborhood Hits	334	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

AATK_MOUSE
NC score	0.004679 (rank : 211)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	227	Target Neighborhood Hits	942	Shared Neighborhood Hits	42
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

KMHN1_HUMAN
NC score	0.004666 (rank : 212)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	227	Target Neighborhood Hits	950	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

RARA_MOUSE
NC score	0.004579 (rank : 213)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	227	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

LATS1_HUMAN
NC score	0.004269 (rank : 214)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	227	Target Neighborhood Hits	1057	Shared Neighborhood Hits	41
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

KLF12_HUMAN
NC score	0.004230 (rank : 215)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	227	Target Neighborhood Hits	717	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4X4, Q5VZM7, Q9UHZ0	Gene names	KLF12, AP2REP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

KLF12_MOUSE
NC score	0.004158 (rank : 216)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	227	Target Neighborhood Hits	721	Shared Neighborhood Hits	19
SwissProt Accessions	O35738	Gene names	Klf12, Ap2rep
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

CD2L5_HUMAN
NC score	0.004069 (rank : 217)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	227	Target Neighborhood Hits	987	Shared Neighborhood Hits	25
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

RARA_HUMAN
NC score	0.004018 (rank : 218)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	227	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

HXD4_HUMAN
NC score	0.003882 (rank : 219)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	227	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	P09016, Q96AU0	Gene names	HOXD4, HOX4B
Domain Architecture
Description	Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13).

GLI1_MOUSE
NC score	0.003411 (rank : 220)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	227	Target Neighborhood Hits	785	Shared Neighborhood Hits	20
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

SP5_MOUSE
NC score	0.003333 (rank : 221)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	227	Target Neighborhood Hits	821	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

SP5_HUMAN
NC score	0.003330 (rank : 222)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	227	Target Neighborhood Hits	832	Shared Neighborhood Hits	25
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

DCAK1_MOUSE
NC score	0.003317 (rank : 223)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	227	Target Neighborhood Hits	867	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

DMD_HUMAN
NC score	0.002629 (rank : 224)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	227	Target Neighborhood Hits	1135	Shared Neighborhood Hits	18
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

STK3_MOUSE
NC score	0.002572 (rank : 225)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	227	Target Neighborhood Hits	869	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

ABL1_MOUSE
NC score	0.002312 (rank : 226)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	227	Target Neighborhood Hits	1178	Shared Neighborhood Hits	40
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PAK6_HUMAN
NC score	0.001847 (rank : 227)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	227	Target Neighborhood Hits	915	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

TCF8_MOUSE
NC score	0.000936 (rank : 228)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	227	Target Neighborhood Hits	1067	Shared Neighborhood Hits	23
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

SP4_MOUSE
NC score	-0.000280 (rank : 229)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	227	Target Neighborhood Hits	759	Shared Neighborhood Hits	17
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.