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Network neighborhood for query Sequence : RUSC2_MOUSE

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RUSC2_MOUSE
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RUSC2_HUMAN
θ value	0 (rank : 1)	NC score	0.934883 (rank : 2)
Query Neighborhood Hits	305	Target Neighborhood Hits	205	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	305	Target Neighborhood Hits	305	Shared Neighborhood Hits	305
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC1_HUMAN
θ value	6.13105e-57 (rank : 3)	NC score	0.686593 (rank : 3)
Query Neighborhood Hits	305	Target Neighborhood Hits	226	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC1_MOUSE
θ value	2.86122e-38 (rank : 4)	NC score	0.657656 (rank : 4)
Query Neighborhood Hits	305	Target Neighborhood Hits	206	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

RHG04_HUMAN
θ value	0.00020696 (rank : 5)	NC score	0.133593 (rank : 19)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

MYCB2_MOUSE
θ value	0.00102713 (rank : 6)	NC score	0.072631 (rank : 134)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ADA2B_MOUSE
θ value	0.00298849 (rank : 7)	NC score	0.018618 (rank : 365)
Query Neighborhood Hits	305	Target Neighborhood Hits	891	Shared Neighborhood Hits	8
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

GPS2_HUMAN
θ value	0.00298849 (rank : 8)	NC score	0.136192 (rank : 15)
Query Neighborhood Hits	305	Target Neighborhood Hits	459	Shared Neighborhood Hits	51
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

K1802_HUMAN
θ value	0.00298849 (rank : 9)	NC score	0.069412 (rank : 149)
Query Neighborhood Hits	305	Target Neighborhood Hits	1378	Shared Neighborhood Hits	113
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SRRM1_MOUSE
θ value	0.00869519 (rank : 10)	NC score	0.117355 (rank : 26)
Query Neighborhood Hits	305	Target Neighborhood Hits	966	Shared Neighborhood Hits	114
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

EFS_MOUSE
θ value	0.0148317 (rank : 11)	NC score	0.214013 (rank : 5)
Query Neighborhood Hits	305	Target Neighborhood Hits	389	Shared Neighborhood Hits	96
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

NCF2_HUMAN
θ value	0.0148317 (rank : 12)	NC score	0.196307 (rank : 6)
Query Neighborhood Hits	305	Target Neighborhood Hits	229	Shared Neighborhood Hits	61
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

STK10_HUMAN
θ value	0.0148317 (rank : 13)	NC score	0.025984 (rank : 330)
Query Neighborhood Hits	305	Target Neighborhood Hits	1921	Shared Neighborhood Hits	75
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ITSN2_HUMAN
θ value	0.0193708 (rank : 14)	NC score	0.115913 (rank : 28)
Query Neighborhood Hits	305	Target Neighborhood Hits	1173	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

RRBP1_MOUSE
θ value	0.0193708 (rank : 15)	NC score	0.042835 (rank : 270)
Query Neighborhood Hits	305	Target Neighborhood Hits	1650	Shared Neighborhood Hits	70
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SH3G1_HUMAN
θ value	0.0193708 (rank : 16)	NC score	0.135837 (rank : 16)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	65
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

TAF4_HUMAN
θ value	0.0193708 (rank : 17)	NC score	0.116584 (rank : 27)
Query Neighborhood Hits	305	Target Neighborhood Hits	687	Shared Neighborhood Hits	87
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

OGFR_HUMAN
θ value	0.0252991 (rank : 18)	NC score	0.130284 (rank : 20)
Query Neighborhood Hits	305	Target Neighborhood Hits	1582	Shared Neighborhood Hits	175
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

KLF13_HUMAN
θ value	0.0330416 (rank : 19)	NC score	0.009475 (rank : 406)
Query Neighborhood Hits	305	Target Neighborhood Hits	739	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

MLL3_HUMAN
θ value	0.0330416 (rank : 20)	NC score	0.098475 (rank : 55)
Query Neighborhood Hits	305	Target Neighborhood Hits	1644	Shared Neighborhood Hits	142
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ITSN1_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.114447 (rank : 32)
Query Neighborhood Hits	305	Target Neighborhood Hits	1757	Shared Neighborhood Hits	125
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PPIP1_HUMAN
θ value	0.0431538 (rank : 22)	NC score	0.150261 (rank : 8)
Query Neighborhood Hits	305	Target Neighborhood Hits	389	Shared Neighborhood Hits	67
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

ATX2_MOUSE
θ value	0.0563607 (rank : 23)	NC score	0.074656 (rank : 127)
Query Neighborhood Hits	305	Target Neighborhood Hits	445	Shared Neighborhood Hits	69
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CTND2_HUMAN
θ value	0.0563607 (rank : 24)	NC score	0.055652 (rank : 220)
Query Neighborhood Hits	305	Target Neighborhood Hits	333	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

GP152_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.036516 (rank : 286)
Query Neighborhood Hits	305	Target Neighborhood Hits	607	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

GRAP_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.149617 (rank : 9)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	72
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

ITSN2_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.108156 (rank : 38)
Query Neighborhood Hits	305	Target Neighborhood Hits	1371	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RANB3_HUMAN
θ value	0.0563607 (rank : 28)	NC score	0.066520 (rank : 162)
Query Neighborhood Hits	305	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

GAK_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.023402 (rank : 345)
Query Neighborhood Hits	305	Target Neighborhood Hits	1028	Shared Neighborhood Hits	52
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

MLL3_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.087298 (rank : 88)
Query Neighborhood Hits	305	Target Neighborhood Hits	1399	Shared Neighborhood Hits	125
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SYN1_MOUSE
θ value	0.0736092 (rank : 31)	NC score	0.088556 (rank : 80)
Query Neighborhood Hits	305	Target Neighborhood Hits	363	Shared Neighborhood Hits	78
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CSKI2_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.044620 (rank : 265)
Query Neighborhood Hits	305	Target Neighborhood Hits	812	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GRAP2_MOUSE
θ value	0.0961366 (rank : 33)	NC score	0.143917 (rank : 10)
Query Neighborhood Hits	305	Target Neighborhood Hits	297	Shared Neighborhood Hits	70
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

ITSN1_MOUSE
θ value	0.0961366 (rank : 34)	NC score	0.114990 (rank : 29)
Query Neighborhood Hits	305	Target Neighborhood Hits	1669	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NFH_MOUSE
θ value	0.0961366 (rank : 35)	NC score	0.077367 (rank : 121)
Query Neighborhood Hits	305	Target Neighborhood Hits	2247	Shared Neighborhood Hits	169
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PDZD2_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.072424 (rank : 136)
Query Neighborhood Hits	305	Target Neighborhood Hits	772	Shared Neighborhood Hits	91
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RERE_MOUSE
θ value	0.0961366 (rank : 37)	NC score	0.080301 (rank : 108)
Query Neighborhood Hits	305	Target Neighborhood Hits	785	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SPTA1_HUMAN
θ value	0.0961366 (rank : 38)	NC score	0.080241 (rank : 109)
Query Neighborhood Hits	305	Target Neighborhood Hits	748	Shared Neighborhood Hits	64
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CO039_HUMAN
θ value	0.125558 (rank : 39)	NC score	0.078074 (rank : 118)
Query Neighborhood Hits	305	Target Neighborhood Hits	264	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO1A2_MOUSE
θ value	0.125558 (rank : 40)	NC score	0.039937 (rank : 275)
Query Neighborhood Hits	305	Target Neighborhood Hits	388	Shared Neighborhood Hits	50
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

GRAP2_HUMAN
θ value	0.125558 (rank : 41)	NC score	0.142891 (rank : 11)
Query Neighborhood Hits	305	Target Neighborhood Hits	304	Shared Neighborhood Hits	74
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

JIP3_HUMAN
θ value	0.125558 (rank : 42)	NC score	0.049957 (rank : 255)
Query Neighborhood Hits	305	Target Neighborhood Hits	1039	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MK07_MOUSE
θ value	0.125558 (rank : 43)	NC score	0.020632 (rank : 357)
Query Neighborhood Hits	305	Target Neighborhood Hits	1054	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MUCDL_HUMAN
θ value	0.125558 (rank : 44)	NC score	0.076607 (rank : 124)
Query Neighborhood Hits	305	Target Neighborhood Hits	777	Shared Neighborhood Hits	120
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SPTA2_HUMAN
θ value	0.125558 (rank : 45)	NC score	0.072331 (rank : 138)
Query Neighborhood Hits	305	Target Neighborhood Hits	888	Shared Neighborhood Hits	73
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ATN1_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.104457 (rank : 45)
Query Neighborhood Hits	305	Target Neighborhood Hits	676	Shared Neighborhood Hits	91
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BSN_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.098093 (rank : 56)
Query Neighborhood Hits	305	Target Neighborhood Hits	1537	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

EWS_HUMAN
θ value	0.163984 (rank : 48)	NC score	0.064269 (rank : 175)
Query Neighborhood Hits	305	Target Neighborhood Hits	249	Shared Neighborhood Hits	29
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

HCLS1_HUMAN
θ value	0.163984 (rank : 49)	NC score	0.127549 (rank : 22)
Query Neighborhood Hits	305	Target Neighborhood Hits	358	Shared Neighborhood Hits	92
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

SYN1_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.084505 (rank : 97)
Query Neighborhood Hits	305	Target Neighborhood Hits	419	Shared Neighborhood Hits	81
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TARA_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.088028 (rank : 86)
Query Neighborhood Hits	305	Target Neighborhood Hits	1626	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

AKTS1_MOUSE
θ value	0.21417 (rank : 52)	NC score	0.066221 (rank : 164)
Query Neighborhood Hits	305	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D1F4	Gene names	Akt1s1, Pras
Domain Architecture	No domain graphic available
Description	Proline-rich AKT1 substrate 1 (Proline-rich AKT substrate).

CAC1G_HUMAN
θ value	0.21417 (rank : 53)	NC score	0.058030 (rank : 205)
Query Neighborhood Hits	305	Target Neighborhood Hits	587	Shared Neighborhood Hits	88
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DNMBP_HUMAN
θ value	0.21417 (rank : 54)	NC score	0.119648 (rank : 25)
Query Neighborhood Hits	305	Target Neighborhood Hits	413	Shared Neighborhood Hits	69
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

GRAP_MOUSE
θ value	0.21417 (rank : 55)	NC score	0.140670 (rank : 13)
Query Neighborhood Hits	305	Target Neighborhood Hits	309	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

K1543_MOUSE
θ value	0.21417 (rank : 56)	NC score	0.077792 (rank : 120)
Query Neighborhood Hits	305	Target Neighborhood Hits	497	Shared Neighborhood Hits	71
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PCQAP_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.088440 (rank : 83)
Query Neighborhood Hits	305	Target Neighborhood Hits	549	Shared Neighborhood Hits	58
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

SPEG_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.023299 (rank : 347)
Query Neighborhood Hits	305	Target Neighborhood Hits	1762	Shared Neighborhood Hits	111
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TCGAP_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.080135 (rank : 110)
Query Neighborhood Hits	305	Target Neighborhood Hits	409	Shared Neighborhood Hits	82
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

EFS_HUMAN
θ value	0.279714 (rank : 60)	NC score	0.193901 (rank : 7)
Query Neighborhood Hits	305	Target Neighborhood Hits	348	Shared Neighborhood Hits	94
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FYN_HUMAN
θ value	0.279714 (rank : 61)	NC score	0.040471 (rank : 274)
Query Neighborhood Hits	305	Target Neighborhood Hits	1078	Shared Neighborhood Hits	75
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	0.279714 (rank : 62)	NC score	0.040967 (rank : 272)
Query Neighborhood Hits	305	Target Neighborhood Hits	1073	Shared Neighborhood Hits	75
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GRB2_HUMAN
θ value	0.279714 (rank : 63)	NC score	0.135464 (rank : 17)
Query Neighborhood Hits	305	Target Neighborhood Hits	310	Shared Neighborhood Hits	69
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.279714 (rank : 64)	NC score	0.135264 (rank : 18)
Query Neighborhood Hits	305	Target Neighborhood Hits	312	Shared Neighborhood Hits	69
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

KIF1C_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.012379 (rank : 397)
Query Neighborhood Hits	305	Target Neighborhood Hits	128	Shared Neighborhood Hits	8
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

MK07_HUMAN
θ value	0.279714 (rank : 66)	NC score	0.019637 (rank : 361)
Query Neighborhood Hits	305	Target Neighborhood Hits	1087	Shared Neighborhood Hits	64
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

SAPS1_HUMAN
θ value	0.279714 (rank : 67)	NC score	0.071299 (rank : 144)
Query Neighborhood Hits	305	Target Neighborhood Hits	704	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

NCOA6_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.100156 (rank : 53)
Query Neighborhood Hits	305	Target Neighborhood Hits	1202	Shared Neighborhood Hits	153
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SYP2L_HUMAN
θ value	0.365318 (rank : 69)	NC score	0.065049 (rank : 170)
Query Neighborhood Hits	305	Target Neighborhood Hits	400	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TBCD3_HUMAN
θ value	0.365318 (rank : 70)	NC score	0.032866 (rank : 302)
Query Neighborhood Hits	305	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

EP400_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.043616 (rank : 266)
Query Neighborhood Hits	305	Target Neighborhood Hits	556	Shared Neighborhood Hits	69
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EWS_MOUSE
θ value	0.47712 (rank : 72)	NC score	0.059184 (rank : 200)
Query Neighborhood Hits	305	Target Neighborhood Hits	271	Shared Neighborhood Hits	33
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

FOG1_HUMAN
θ value	0.47712 (rank : 73)	NC score	0.023394 (rank : 346)
Query Neighborhood Hits	305	Target Neighborhood Hits	981	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXJ2_MOUSE
θ value	0.47712 (rank : 74)	NC score	0.021972 (rank : 351)
Query Neighborhood Hits	305	Target Neighborhood Hits	151	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ES18	Gene names	Foxj2, Fhx
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GLIS3_HUMAN
θ value	0.47712 (rank : 75)	NC score	0.007671 (rank : 416)
Query Neighborhood Hits	305	Target Neighborhood Hits	758	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

LDB3_MOUSE
θ value	0.47712 (rank : 76)	NC score	0.039242 (rank : 277)
Query Neighborhood Hits	305	Target Neighborhood Hits	510	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MATK_HUMAN
θ value	0.47712 (rank : 77)	NC score	0.027604 (rank : 321)
Query Neighborhood Hits	305	Target Neighborhood Hits	954	Shared Neighborhood Hits	45
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

BSN_MOUSE
θ value	0.62314 (rank : 78)	NC score	0.113282 (rank : 33)
Query Neighborhood Hits	305	Target Neighborhood Hits	2057	Shared Neighborhood Hits	184
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CK024_HUMAN
θ value	0.62314 (rank : 79)	NC score	0.107499 (rank : 39)
Query Neighborhood Hits	305	Target Neighborhood Hits	408	Shared Neighborhood Hits	73
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

GCNL2_MOUSE
θ value	0.62314 (rank : 80)	NC score	0.048697 (rank : 256)
Query Neighborhood Hits	305	Target Neighborhood Hits	146	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

HCN4_MOUSE
θ value	0.62314 (rank : 81)	NC score	0.038230 (rank : 281)
Query Neighborhood Hits	305	Target Neighborhood Hits	284	Shared Neighborhood Hits	55
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

NCK1_HUMAN
θ value	0.62314 (rank : 82)	NC score	0.120795 (rank : 24)
Query Neighborhood Hits	305	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

PRB3_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.091968 (rank : 68)
Query Neighborhood Hits	305	Target Neighborhood Hits	318	Shared Neighborhood Hits	61
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

RP3A_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.032930 (rank : 301)
Query Neighborhood Hits	305	Target Neighborhood Hits	305	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

UBXD1_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.039012 (rank : 278)
Query Neighborhood Hits	305	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZV1, Q96AH1, Q96IK9, Q9BZV0	Gene names	UBXD1, UBXDC2
Domain Architecture
Description	UBX domain-containing protein 1.

WASIP_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.084786 (rank : 94)
Query Neighborhood Hits	305	Target Neighborhood Hits	392	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

AATK_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.028338 (rank : 319)
Query Neighborhood Hits	305	Target Neighborhood Hits	1243	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ABL1_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.035702 (rank : 292)
Query Neighborhood Hits	305	Target Neighborhood Hits	1220	Shared Neighborhood Hits	95
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	0.813845 (rank : 89)	NC score	0.035778 (rank : 290)
Query Neighborhood Hits	305	Target Neighborhood Hits	1178	Shared Neighborhood Hits	93
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CTND2_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.041830 (rank : 271)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

DDEF2_MOUSE
θ value	0.813845 (rank : 91)	NC score	0.073168 (rank : 132)
Query Neighborhood Hits	305	Target Neighborhood Hits	625	Shared Neighborhood Hits	85
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

EGR1_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.006804 (rank : 417)
Query Neighborhood Hits	305	Target Neighborhood Hits	816	Shared Neighborhood Hits	33
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

EP300_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.066966 (rank : 159)
Query Neighborhood Hits	305	Target Neighborhood Hits	821	Shared Neighborhood Hits	99
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

LASP1_HUMAN
θ value	0.813845 (rank : 94)	NC score	0.092756 (rank : 65)
Query Neighborhood Hits	305	Target Neighborhood Hits	293	Shared Neighborhood Hits	56
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LRC56_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.058309 (rank : 204)
Query Neighborhood Hits	305	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

NSD1_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.048573 (rank : 257)
Query Neighborhood Hits	305	Target Neighborhood Hits	427	Shared Neighborhood Hits	56
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

RECQ5_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.054160 (rank : 225)
Query Neighborhood Hits	305	Target Neighborhood Hits	390	Shared Neighborhood Hits	67
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

TENN_MOUSE
θ value	0.813845 (rank : 98)	NC score	0.016297 (rank : 375)
Query Neighborhood Hits	305	Target Neighborhood Hits	484	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ZAR1_MOUSE
θ value	0.813845 (rank : 99)	NC score	0.076733 (rank : 123)
Query Neighborhood Hits	305	Target Neighborhood Hits	254	Shared Neighborhood Hits	45
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ARI1B_HUMAN
θ value	1.06291 (rank : 100)	NC score	0.074298 (rank : 128)
Query Neighborhood Hits	305	Target Neighborhood Hits	567	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARP5_MOUSE
θ value	1.06291 (rank : 101)	NC score	0.021712 (rank : 353)
Query Neighborhood Hits	305	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

BCAR1_MOUSE
θ value	1.06291 (rank : 102)	NC score	0.140670 (rank : 12)
Query Neighborhood Hits	305	Target Neighborhood Hits	438	Shared Neighborhood Hits	103
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BEGIN_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.030848 (rank : 311)
Query Neighborhood Hits	305	Target Neighborhood Hits	454	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CIC_HUMAN
θ value	1.06291 (rank : 104)	NC score	0.078380 (rank : 117)
Query Neighborhood Hits	305	Target Neighborhood Hits	992	Shared Neighborhood Hits	133
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO5A2_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.040727 (rank : 273)
Query Neighborhood Hits	305	Target Neighborhood Hits	760	Shared Neighborhood Hits	84
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

GCC1_MOUSE
θ value	1.06291 (rank : 106)	NC score	0.031091 (rank : 308)
Query Neighborhood Hits	305	Target Neighborhood Hits	777	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCNL2_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.046267 (rank : 262)
Query Neighborhood Hits	305	Target Neighborhood Hits	159	Shared Neighborhood Hits	33
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

HAP1_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.027594 (rank : 322)
Query Neighborhood Hits	305	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

MLL4_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.063699 (rank : 181)
Query Neighborhood Hits	305	Target Neighborhood Hits	722	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NCOA6_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.114682 (rank : 30)
Query Neighborhood Hits	305	Target Neighborhood Hits	1076	Shared Neighborhood Hits	145
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RUNX1_MOUSE
θ value	1.06291 (rank : 111)	NC score	0.026227 (rank : 329)
Query Neighborhood Hits	305	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

SLIK1_MOUSE
θ value	1.06291 (rank : 112)	NC score	0.009126 (rank : 408)
Query Neighborhood Hits	305	Target Neighborhood Hits	333	Shared Neighborhood Hits	11
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

ABL2_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.030967 (rank : 310)
Query Neighborhood Hits	305	Target Neighborhood Hits	1045	Shared Neighborhood Hits	61
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

BAT3_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.072419 (rank : 137)
Query Neighborhood Hits	305	Target Neighborhood Hits	490	Shared Neighborhood Hits	78
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.079016 (rank : 114)
Query Neighborhood Hits	305	Target Neighborhood Hits	518	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BCAR1_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.138472 (rank : 14)
Query Neighborhood Hits	305	Target Neighborhood Hits	554	Shared Neighborhood Hits	114
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CEBPE_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.033910 (rank : 297)
Query Neighborhood Hits	305	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

HCN2_MOUSE
θ value	1.38821 (rank : 118)	NC score	0.038262 (rank : 280)
Query Neighborhood Hits	305	Target Neighborhood Hits	278	Shared Neighborhood Hits	55
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

JUNB_MOUSE
θ value	1.38821 (rank : 119)	NC score	0.025422 (rank : 337)
Query Neighborhood Hits	305	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

MILK2_HUMAN
θ value	1.38821 (rank : 120)	NC score	0.035151 (rank : 293)
Query Neighborhood Hits	305	Target Neighborhood Hits	457	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

PRDM2_HUMAN
θ value	1.38821 (rank : 121)	NC score	0.021384 (rank : 354)
Query Neighborhood Hits	305	Target Neighborhood Hits	1135	Shared Neighborhood Hits	69
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

REV1_MOUSE
θ value	1.38821 (rank : 122)	NC score	0.029095 (rank : 316)
Query Neighborhood Hits	305	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

SHAN1_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.060345 (rank : 193)
Query Neighborhood Hits	305	Target Neighborhood Hits	1041	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SMG7_MOUSE
θ value	1.38821 (rank : 124)	NC score	0.045837 (rank : 264)
Query Neighborhood Hits	305	Target Neighborhood Hits	113	Shared Neighborhood Hits	22
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

STAM2_MOUSE
θ value	1.38821 (rank : 125)	NC score	0.102086 (rank : 51)
Query Neighborhood Hits	305	Target Neighborhood Hits	285	Shared Neighborhood Hits	69
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TIF1G_HUMAN
θ value	1.38821 (rank : 126)	NC score	0.025451 (rank : 336)
Query Neighborhood Hits	305	Target Neighborhood Hits	410	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

ARHG7_MOUSE
θ value	1.81305 (rank : 127)	NC score	0.089929 (rank : 74)
Query Neighborhood Hits	305	Target Neighborhood Hits	396	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

BAI1_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.015982 (rank : 376)
Query Neighborhood Hits	305	Target Neighborhood Hits	340	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

DMWD_MOUSE
θ value	1.81305 (rank : 129)	NC score	0.023762 (rank : 344)
Query Neighborhood Hits	305	Target Neighborhood Hits	282	Shared Neighborhood Hits	18
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

EPS8_MOUSE
θ value	1.81305 (rank : 130)	NC score	0.048054 (rank : 260)
Query Neighborhood Hits	305	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

GGN_HUMAN
θ value	1.81305 (rank : 131)	NC score	0.064040 (rank : 176)
Query Neighborhood Hits	305	Target Neighborhood Hits	269	Shared Neighborhood Hits	53
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GSCR1_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.082225 (rank : 101)
Query Neighborhood Hits	305	Target Neighborhood Hits	674	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

JIP1_MOUSE
θ value	1.81305 (rank : 133)	NC score	0.051846 (rank : 243)
Query Neighborhood Hits	305	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

LIMD1_MOUSE
θ value	1.81305 (rank : 134)	NC score	0.032834 (rank : 303)
Query Neighborhood Hits	305	Target Neighborhood Hits	291	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MEGF9_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.020181 (rank : 360)
Query Neighborhood Hits	305	Target Neighborhood Hits	557	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NCOR2_MOUSE
θ value	1.81305 (rank : 136)	NC score	0.048281 (rank : 258)
Query Neighborhood Hits	305	Target Neighborhood Hits	790	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

ONEC2_MOUSE
θ value	1.81305 (rank : 137)	NC score	0.019231 (rank : 363)
Query Neighborhood Hits	305	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q6XBJ3	Gene names	Onecut2, Oc2
Domain Architecture	No domain graphic available
Description	One cut domain family member 2 (Transcription factor ONECUT-2) (OC-2).

OSTF1_HUMAN
θ value	1.81305 (rank : 138)	NC score	0.090219 (rank : 73)
Query Neighborhood Hits	305	Target Neighborhood Hits	466	Shared Neighborhood Hits	68
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PO121_MOUSE
θ value	1.81305 (rank : 139)	NC score	0.052367 (rank : 238)
Query Neighborhood Hits	305	Target Neighborhood Hits	345	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRG4_MOUSE
θ value	1.81305 (rank : 140)	NC score	0.055509 (rank : 221)
Query Neighborhood Hits	305	Target Neighborhood Hits	624	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SCN8A_HUMAN
θ value	1.81305 (rank : 141)	NC score	0.018521 (rank : 366)
Query Neighborhood Hits	305	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	1.81305 (rank : 142)	NC score	0.017940 (rank : 369)
Query Neighborhood Hits	305	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SH3G1_MOUSE
θ value	1.81305 (rank : 143)	NC score	0.114494 (rank : 31)
Query Neighborhood Hits	305	Target Neighborhood Hits	291	Shared Neighborhood Hits	66
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SRMS_MOUSE
θ value	1.81305 (rank : 144)	NC score	0.024481 (rank : 341)
Query Neighborhood Hits	305	Target Neighborhood Hits	964	Shared Neighborhood Hits	47
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

USBP1_HUMAN
θ value	1.81305 (rank : 145)	NC score	0.027354 (rank : 325)
Query Neighborhood Hits	305	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

WNK2_HUMAN
θ value	1.81305 (rank : 146)	NC score	0.025895 (rank : 332)
Query Neighborhood Hits	305	Target Neighborhood Hits	1407	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AHI1_MOUSE
θ value	2.36792 (rank : 147)	NC score	0.090272 (rank : 72)
Query Neighborhood Hits	305	Target Neighborhood Hits	496	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ARI5B_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.032706 (rank : 304)
Query Neighborhood Hits	305	Target Neighborhood Hits	328	Shared Neighborhood Hits	25
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

BAI1_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.017633 (rank : 370)
Query Neighborhood Hits	305	Target Neighborhood Hits	375	Shared Neighborhood Hits	32
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BCOR_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.025602 (rank : 334)
Query Neighborhood Hits	305	Target Neighborhood Hits	609	Shared Neighborhood Hits	46
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CHD9_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.014563 (rank : 384)
Query Neighborhood Hits	305	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CO002_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.059288 (rank : 199)
Query Neighborhood Hits	305	Target Neighborhood Hits	387	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

HAND1_MOUSE
θ value	2.36792 (rank : 153)	NC score	0.015709 (rank : 377)
Query Neighborhood Hits	305	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

HORN_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.029952 (rank : 314)
Query Neighborhood Hits	305	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

IASPP_MOUSE
θ value	2.36792 (rank : 155)	NC score	0.103509 (rank : 48)
Query Neighborhood Hits	305	Target Neighborhood Hits	1024	Shared Neighborhood Hits	148
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MARCS_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.077110 (rank : 122)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	38
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MKL1_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.072033 (rank : 141)
Query Neighborhood Hits	305	Target Neighborhood Hits	667	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCF4_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.130007 (rank : 21)
Query Neighborhood Hits	305	Target Neighborhood Hits	161	Shared Neighborhood Hits	54
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

PCLO_MOUSE
θ value	2.36792 (rank : 159)	NC score	0.087163 (rank : 89)
Query Neighborhood Hits	305	Target Neighborhood Hits	2275	Shared Neighborhood Hits	185
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRG4_HUMAN
θ value	2.36792 (rank : 160)	NC score	0.061253 (rank : 188)
Query Neighborhood Hits	305	Target Neighborhood Hits	764	Shared Neighborhood Hits	72
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RAIN_HUMAN
θ value	2.36792 (rank : 161)	NC score	0.020230 (rank : 359)
Query Neighborhood Hits	305	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

SALL1_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.004430 (rank : 425)
Query Neighborhood Hits	305	Target Neighborhood Hits	821	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

SC24C_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.066270 (rank : 163)
Query Neighborhood Hits	305	Target Neighborhood Hits	662	Shared Neighborhood Hits	99
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SEM5A_MOUSE
θ value	2.36792 (rank : 164)	NC score	0.008613 (rank : 411)
Query Neighborhood Hits	305	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SH3G2_MOUSE
θ value	2.36792 (rank : 165)	NC score	0.112544 (rank : 35)
Query Neighborhood Hits	305	Target Neighborhood Hits	319	Shared Neighborhood Hits	69
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SHAN2_HUMAN
θ value	2.36792 (rank : 166)	NC score	0.039317 (rank : 276)
Query Neighborhood Hits	305	Target Neighborhood Hits	346	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SRRM1_HUMAN
θ value	2.36792 (rank : 167)	NC score	0.083671 (rank : 99)
Query Neighborhood Hits	305	Target Neighborhood Hits	690	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TXK_MOUSE
θ value	2.36792 (rank : 168)	NC score	0.030989 (rank : 309)
Query Neighborhood Hits	305	Target Neighborhood Hits	980	Shared Neighborhood Hits	62
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

USH1C_MOUSE
θ value	2.36792 (rank : 169)	NC score	0.038658 (rank : 279)
Query Neighborhood Hits	305	Target Neighborhood Hits	557	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ZN219_HUMAN
θ value	2.36792 (rank : 170)	NC score	0.010759 (rank : 402)
Query Neighborhood Hits	305	Target Neighborhood Hits	876	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

B4GT1_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.027969 (rank : 320)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	21
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CAC1H_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.029313 (rank : 315)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	45
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CHST8_MOUSE
θ value	3.0926 (rank : 173)	NC score	0.013645 (rank : 387)
Query Neighborhood Hits	305	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQ86, Q76EC6, Q80XD4	Gene names	Chst8
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 8 (EC 2.8.2.-) (N-acetylgalactosamine-4- O-sulfotransferase 1) (GalNAc-4-O-sulfotransferase 1) (GalNAc-4-ST1) (GalNAc4ST-1).

CO5A3_HUMAN
θ value	3.0926 (rank : 174)	NC score	0.030035 (rank : 313)
Query Neighborhood Hits	305	Target Neighborhood Hits	433	Shared Neighborhood Hits	43
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

COBA1_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.032699 (rank : 305)
Query Neighborhood Hits	305	Target Neighborhood Hits	491	Shared Neighborhood Hits	61
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	3.0926 (rank : 176)	NC score	0.032061 (rank : 307)
Query Neighborhood Hits	305	Target Neighborhood Hits	487	Shared Neighborhood Hits	59
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

DACT1_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.042908 (rank : 268)
Query Neighborhood Hits	305	Target Neighborhood Hits	228	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

DDEF2_HUMAN
θ value	3.0926 (rank : 178)	NC score	0.065585 (rank : 167)
Query Neighborhood Hits	305	Target Neighborhood Hits	599	Shared Neighborhood Hits	89
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DNMBP_MOUSE
θ value	3.0926 (rank : 179)	NC score	0.099888 (rank : 54)
Query Neighborhood Hits	305	Target Neighborhood Hits	435	Shared Neighborhood Hits	76
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FSTL4_HUMAN
θ value	3.0926 (rank : 180)	NC score	0.008900 (rank : 410)
Query Neighborhood Hits	305	Target Neighborhood Hits	344	Shared Neighborhood Hits	5
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

HXD3_MOUSE
θ value	3.0926 (rank : 181)	NC score	0.013269 (rank : 389)
Query Neighborhood Hits	305	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

IASPP_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.091376 (rank : 70)
Query Neighborhood Hits	305	Target Neighborhood Hits	688	Shared Neighborhood Hits	112
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LAP4_HUMAN
θ value	3.0926 (rank : 183)	NC score	0.014306 (rank : 386)
Query Neighborhood Hits	305	Target Neighborhood Hits	608	Shared Neighborhood Hits	36
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MYO1E_HUMAN
θ value	3.0926 (rank : 184)	NC score	0.035742 (rank : 291)
Query Neighborhood Hits	305	Target Neighborhood Hits	293	Shared Neighborhood Hits	64
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

NCOR1_MOUSE
θ value	3.0926 (rank : 185)	NC score	0.033800 (rank : 298)
Query Neighborhood Hits	305	Target Neighborhood Hits	521	Shared Neighborhood Hits	44
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PHX2A_HUMAN
θ value	3.0926 (rank : 186)	NC score	0.006208 (rank : 418)
Query Neighborhood Hits	305	Target Neighborhood Hits	345	Shared Neighborhood Hits	10
SwissProt Accessions	O14813, Q8IVZ2	Gene names	PHOX2A, ARIX, PMX2A
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein).

SELPL_MOUSE
θ value	3.0926 (rank : 187)	NC score	0.104147 (rank : 46)
Query Neighborhood Hits	305	Target Neighborhood Hits	588	Shared Neighborhood Hits	95
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SNPC4_HUMAN
θ value	3.0926 (rank : 188)	NC score	0.060715 (rank : 191)
Query Neighborhood Hits	305	Target Neighborhood Hits	589	Shared Neighborhood Hits	89
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SPTA1_MOUSE
θ value	3.0926 (rank : 189)	NC score	0.067915 (rank : 156)
Query Neighborhood Hits	305	Target Neighborhood Hits	675	Shared Neighborhood Hits	65
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TACC3_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.034976 (rank : 294)
Query Neighborhood Hits	305	Target Neighborhood Hits	779	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TCGAP_HUMAN
θ value	3.0926 (rank : 191)	NC score	0.103756 (rank : 47)
Query Neighborhood Hits	305	Target Neighborhood Hits	872	Shared Neighborhood Hits	142
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TGON2_HUMAN
θ value	3.0926 (rank : 192)	NC score	0.060287 (rank : 194)
Query Neighborhood Hits	305	Target Neighborhood Hits	1037	Shared Neighborhood Hits	91
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

WASP_HUMAN
θ value	3.0926 (rank : 193)	NC score	0.042849 (rank : 269)
Query Neighborhood Hits	305	Target Neighborhood Hits	195	Shared Neighborhood Hits	39
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

ZN592_MOUSE
θ value	3.0926 (rank : 194)	NC score	0.004770 (rank : 424)
Query Neighborhood Hits	305	Target Neighborhood Hits	768	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

3BP1_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.046950 (rank : 261)
Query Neighborhood Hits	305	Target Neighborhood Hits	376	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ANM2_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.075956 (rank : 125)
Query Neighborhood Hits	305	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

APBA3_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.018811 (rank : 364)
Query Neighborhood Hits	305	Target Neighborhood Hits	201	Shared Neighborhood Hits	18
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHG7_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.081177 (rank : 104)
Query Neighborhood Hits	305	Target Neighborhood Hits	347	Shared Neighborhood Hits	63
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG9_HUMAN
θ value	4.03905 (rank : 199)	NC score	0.081404 (rank : 103)
Query Neighborhood Hits	305	Target Neighborhood Hits	235	Shared Neighborhood Hits	60
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	4.03905 (rank : 200)	NC score	0.081119 (rank : 105)
Query Neighborhood Hits	305	Target Neighborhood Hits	234	Shared Neighborhood Hits	61
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

BAG3_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.060836 (rank : 190)
Query Neighborhood Hits	305	Target Neighborhood Hits	513	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BAT2_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.082089 (rank : 102)
Query Neighborhood Hits	305	Target Neighborhood Hits	931	Shared Neighborhood Hits	111
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DOCK4_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.025908 (rank : 331)
Query Neighborhood Hits	305	Target Neighborhood Hits	237	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	4.03905 (rank : 204)	NC score	0.027194 (rank : 327)
Query Neighborhood Hits	305	Target Neighborhood Hits	210	Shared Neighborhood Hits	46
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

E41LB_MOUSE
θ value	4.03905 (rank : 205)	NC score	0.008575 (rank : 412)
Query Neighborhood Hits	305	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FOXJ2_HUMAN
θ value	4.03905 (rank : 206)	NC score	0.021902 (rank : 352)
Query Neighborhood Hits	305	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

KCNH6_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.018001 (rank : 368)
Query Neighborhood Hits	305	Target Neighborhood Hits	222	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

OSTF1_MOUSE
θ value	4.03905 (rank : 208)	NC score	0.085690 (rank : 90)
Query Neighborhood Hits	305	Target Neighborhood Hits	467	Shared Neighborhood Hits	68
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PAX5_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.014988 (rank : 381)
Query Neighborhood Hits	305	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	Q02548, O75933	Gene names	PAX5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PAX5_MOUSE
θ value	4.03905 (rank : 210)	NC score	0.015085 (rank : 380)
Query Neighborhood Hits	305	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PEF1_HUMAN
θ value	4.03905 (rank : 211)	NC score	0.023930 (rank : 343)
Query Neighborhood Hits	305	Target Neighborhood Hits	135	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PO2F1_MOUSE
θ value	4.03905 (rank : 212)	NC score	0.012454 (rank : 396)
Query Neighborhood Hits	305	Target Neighborhood Hits	408	Shared Neighborhood Hits	26
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

R3HD2_MOUSE
θ value	4.03905 (rank : 213)	NC score	0.055061 (rank : 222)
Query Neighborhood Hits	305	Target Neighborhood Hits	397	Shared Neighborhood Hits	69
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RGS3_HUMAN
θ value	4.03905 (rank : 214)	NC score	0.057891 (rank : 206)
Query Neighborhood Hits	305	Target Neighborhood Hits	1375	Shared Neighborhood Hits	147
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RXRB_HUMAN
θ value	4.03905 (rank : 215)	NC score	0.009868 (rank : 405)
Query Neighborhood Hits	305	Target Neighborhood Hits	280	Shared Neighborhood Hits	36
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

SMBP2_MOUSE
θ value	4.03905 (rank : 216)	NC score	0.017061 (rank : 374)
Query Neighborhood Hits	305	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

SMRC2_HUMAN
θ value	4.03905 (rank : 217)	NC score	0.033104 (rank : 300)
Query Neighborhood Hits	305	Target Neighborhood Hits	499	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SRRM2_MOUSE
θ value	4.03905 (rank : 218)	NC score	0.084869 (rank : 93)
Query Neighborhood Hits	305	Target Neighborhood Hits	1470	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

VINEX_MOUSE
θ value	4.03905 (rank : 219)	NC score	0.123830 (rank : 23)
Query Neighborhood Hits	305	Target Neighborhood Hits	286	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

YBOX2_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.026311 (rank : 328)
Query Neighborhood Hits	305	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2T7, Q8N4P0	Gene names	YBX2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (Contrin) (MSY2 homolog).

YBOX2_MOUSE
θ value	4.03905 (rank : 221)	NC score	0.025610 (rank : 333)
Query Neighborhood Hits	305	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

ZAR1_HUMAN
θ value	4.03905 (rank : 222)	NC score	0.056377 (rank : 218)
Query Neighborhood Hits	305	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

AFF3_HUMAN
θ value	5.27518 (rank : 223)	NC score	0.022059 (rank : 349)
Query Neighborhood Hits	305	Target Neighborhood Hits	190	Shared Neighborhood Hits	29
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

BORG5_MOUSE
θ value	5.27518 (rank : 224)	NC score	0.020976 (rank : 356)
Query Neighborhood Hits	305	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	Q91W92, Q9D8M1	Gene names	Cdc42ep1, Borg5, Cep1
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5).

CABIN_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.056998 (rank : 214)
Query Neighborhood Hits	305	Target Neighborhood Hits	490	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CCNK_MOUSE
θ value	5.27518 (rank : 226)	NC score	0.043088 (rank : 267)
Query Neighborhood Hits	305	Target Neighborhood Hits	350	Shared Neighborhood Hits	53
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CDN1C_HUMAN
θ value	5.27518 (rank : 227)	NC score	0.052012 (rank : 242)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	32
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CEP68_HUMAN
θ value	5.27518 (rank : 228)	NC score	0.024469 (rank : 342)
Query Neighborhood Hits	305	Target Neighborhood Hits	128	Shared Neighborhood Hits	21
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CIC_MOUSE
θ value	5.27518 (rank : 229)	NC score	0.052086 (rank : 241)
Query Neighborhood Hits	305	Target Neighborhood Hits	742	Shared Neighborhood Hits	99
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

GLIS1_MOUSE
θ value	5.27518 (rank : 230)	NC score	0.003069 (rank : 428)
Query Neighborhood Hits	305	Target Neighborhood Hits	751	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

HXD3_HUMAN
θ value	5.27518 (rank : 231)	NC score	0.015085 (rank : 379)
Query Neighborhood Hits	305	Target Neighborhood Hits	433	Shared Neighborhood Hits	31
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

K1C23_MOUSE
θ value	5.27518 (rank : 232)	NC score	0.006101 (rank : 419)
Query Neighborhood Hits	305	Target Neighborhood Hits	370	Shared Neighborhood Hits	12
SwissProt Accessions	Q99PS0	Gene names	Krt23, Haik1, Krt1-23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

LBXCO_HUMAN
θ value	5.27518 (rank : 233)	NC score	0.024845 (rank : 339)
Query Neighborhood Hits	305	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

LCK_HUMAN
θ value	5.27518 (rank : 234)	NC score	0.027497 (rank : 323)
Query Neighborhood Hits	305	Target Neighborhood Hits	987	Shared Neighborhood Hits	52
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LEUK_HUMAN
θ value	5.27518 (rank : 235)	NC score	0.034328 (rank : 296)
Query Neighborhood Hits	305	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

MDC1_MOUSE
θ value	5.27518 (rank : 236)	NC score	0.089689 (rank : 76)
Query Neighborhood Hits	305	Target Neighborhood Hits	998	Shared Neighborhood Hits	114
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NACAM_MOUSE
θ value	5.27518 (rank : 237)	NC score	0.091653 (rank : 69)
Query Neighborhood Hits	305	Target Neighborhood Hits	1866	Shared Neighborhood Hits	154
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PHLPP_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.025584 (rank : 335)
Query Neighborhood Hits	305	Target Neighborhood Hits	604	Shared Neighborhood Hits	72
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PKHA4_HUMAN
θ value	5.27518 (rank : 239)	NC score	0.032456 (rank : 306)
Query Neighborhood Hits	305	Target Neighborhood Hits	283	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

POLK_MOUSE
θ value	5.27518 (rank : 240)	NC score	0.017123 (rank : 373)
Query Neighborhood Hits	305	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

RIMB1_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.053687 (rank : 230)
Query Neighborhood Hits	305	Target Neighborhood Hits	1479	Shared Neighborhood Hits	132
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TBX21_MOUSE
θ value	5.27518 (rank : 242)	NC score	0.017211 (rank : 371)
Query Neighborhood Hits	305	Target Neighborhood Hits	116	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TCF20_HUMAN
θ value	5.27518 (rank : 243)	NC score	0.035859 (rank : 288)
Query Neighborhood Hits	305	Target Neighborhood Hits	323	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TOB1_MOUSE
θ value	5.27518 (rank : 244)	NC score	0.014735 (rank : 382)
Query Neighborhood Hits	305	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q61471	Gene names	Tob1, Tob, Trob
Domain Architecture
Description	Tob1 protein (Transducer of erbB-2 1).

UBR2_MOUSE
θ value	5.27518 (rank : 245)	NC score	0.011053 (rank : 401)
Query Neighborhood Hits	305	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

ULK1_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.019362 (rank : 362)
Query Neighborhood Hits	305	Target Neighborhood Hits	1214	Shared Neighborhood Hits	90
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ACH10_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.011218 (rank : 400)
Query Neighborhood Hits	305	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZZ6	Gene names	CHRNA10, NACHRA10
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-10 precursor (Nicotinic acetylcholine receptor subunit alpha 10) (NACHR alpha 10).

ATS14_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.013065 (rank : 390)
Query Neighborhood Hits	305	Target Neighborhood Hits	382	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

B4GT1_MOUSE
θ value	6.88961 (rank : 249)	NC score	0.012685 (rank : 393)
Query Neighborhood Hits	305	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

BARH2_MOUSE
θ value	6.88961 (rank : 250)	NC score	0.005703 (rank : 421)
Query Neighborhood Hits	305	Target Neighborhood Hits	397	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VIB5, Q66L43	Gene names	Barhl2, Barh1, Mbh1
Domain Architecture	No domain graphic available
Description	BarH-like 2 homeobox protein (Bar-class homeodomain protein MBH1) (Homeobox protein B-H1).

BAT2_MOUSE
θ value	6.88961 (rank : 251)	NC score	0.079641 (rank : 111)
Query Neighborhood Hits	305	Target Neighborhood Hits	947	Shared Neighborhood Hits	121
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DNER_HUMAN
θ value	6.88961 (rank : 252)	NC score	0.004855 (rank : 423)
Query Neighborhood Hits	305	Target Neighborhood Hits	460	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DOT1L_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.059700 (rank : 197)
Query Neighborhood Hits	305	Target Neighborhood Hits	660	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ES8L3_MOUSE
θ value	6.88961 (rank : 254)	NC score	0.056783 (rank : 215)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	55
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ETV4_HUMAN
θ value	6.88961 (rank : 255)	NC score	0.007873 (rank : 415)
Query Neighborhood Hits	305	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

M3K1_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.010535 (rank : 404)
Query Neighborhood Hits	305	Target Neighborhood Hits	952	Shared Neighborhood Hits	35
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MAST4_HUMAN
θ value	6.88961 (rank : 257)	NC score	0.025042 (rank : 338)
Query Neighborhood Hits	305	Target Neighborhood Hits	1804	Shared Neighborhood Hits	139
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NPHP1_MOUSE
θ value	6.88961 (rank : 258)	NC score	0.104462 (rank : 44)
Query Neighborhood Hits	305	Target Neighborhood Hits	267	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

OST3B_HUMAN
θ value	6.88961 (rank : 259)	NC score	0.005525 (rank : 422)
Query Neighborhood Hits	305	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

PGBM_HUMAN
θ value	6.88961 (rank : 260)	NC score	0.003141 (rank : 427)
Query Neighborhood Hits	305	Target Neighborhood Hits	1113	Shared Neighborhood Hits	27
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PININ_MOUSE
θ value	6.88961 (rank : 261)	NC score	0.022325 (rank : 348)
Query Neighborhood Hits	305	Target Neighborhood Hits	777	Shared Neighborhood Hits	37
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

POLS_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.011226 (rank : 399)
Query Neighborhood Hits	305	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q5XG87, O43289, Q9Y6C1	Gene names	POLS, TRF4
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7) (Topoisomerase-related function protein 4-1) (TRF4-1) (LAK-1) (DNA polymerase kappa).

SCND2_HUMAN
θ value	6.88961 (rank : 263)	NC score	0.008289 (rank : 413)
Query Neighborhood Hits	305	Target Neighborhood Hits	86	Shared Neighborhood Hits	11
SwissProt Accessions	Q9GZW5, Q9H9G1	Gene names	SCAND2
Domain Architecture
Description	SCAN domain-containing protein 2.

SRTD2_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.017194 (rank : 372)
Query Neighborhood Hits	305	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

STAB1_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.003864 (rank : 426)
Query Neighborhood Hits	305	Target Neighborhood Hits	546	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TAF6_HUMAN
θ value	6.88961 (rank : 266)	NC score	0.030848 (rank : 312)
Query Neighborhood Hits	305	Target Neighborhood Hits	127	Shared Neighborhood Hits	34
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

TCF19_MOUSE
θ value	6.88961 (rank : 267)	NC score	0.038004 (rank : 282)
Query Neighborhood Hits	305	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

ZN414_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.020541 (rank : 358)
Query Neighborhood Hits	305	Target Neighborhood Hits	548	Shared Neighborhood Hits	29
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

ANM2_MOUSE
θ value	8.99809 (rank : 269)	NC score	0.072159 (rank : 139)
Query Neighborhood Hits	305	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARI5B_MOUSE
θ value	8.99809 (rank : 270)	NC score	0.028600 (rank : 317)
Query Neighborhood Hits	305	Target Neighborhood Hits	158	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

CO1A1_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.036961 (rank : 284)
Query Neighborhood Hits	305	Target Neighborhood Hits	475	Shared Neighborhood Hits	58
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO2A1_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.035801 (rank : 289)
Query Neighborhood Hits	305	Target Neighborhood Hits	486	Shared Neighborhood Hits	67
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO3A1_MOUSE
θ value	8.99809 (rank : 273)	NC score	0.036548 (rank : 285)
Query Neighborhood Hits	305	Target Neighborhood Hits	466	Shared Neighborhood Hits	60
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CSKI1_MOUSE
θ value	8.99809 (rank : 274)	NC score	0.036511 (rank : 287)
Query Neighborhood Hits	305	Target Neighborhood Hits	1031	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.037736 (rank : 283)
Query Neighborhood Hits	305	Target Neighborhood Hits	747	Shared Neighborhood Hits	91
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSPG3_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.012860 (rank : 392)
Query Neighborhood Hits	305	Target Neighborhood Hits	657	Shared Neighborhood Hits	38
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DUS8_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.014437 (rank : 385)
Query Neighborhood Hits	305	Target Neighborhood Hits	161	Shared Neighborhood Hits	26
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

E41LB_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.007977 (rank : 414)
Query Neighborhood Hits	305	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

EHMT2_MOUSE
θ value	8.99809 (rank : 279)	NC score	0.028449 (rank : 318)
Query Neighborhood Hits	305	Target Neighborhood Hits	750	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FOXM1_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.012651 (rank : 394)
Query Neighborhood Hits	305	Target Neighborhood Hits	167	Shared Neighborhood Hits	18
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

GRASP_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.018383 (rank : 367)
Query Neighborhood Hits	305	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

HCN4_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.034796 (rank : 295)
Query Neighborhood Hits	305	Target Neighborhood Hits	303	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HXA3_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.015424 (rank : 378)
Query Neighborhood Hits	305	Target Neighborhood Hits	558	Shared Neighborhood Hits	55
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HXB3_MOUSE
θ value	8.99809 (rank : 284)	NC score	0.010691 (rank : 403)
Query Neighborhood Hits	305	Target Neighborhood Hits	493	Shared Neighborhood Hits	32
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

JHD2C_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.011282 (rank : 398)
Query Neighborhood Hits	305	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

LSR_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.012534 (rank : 395)
Query Neighborhood Hits	305	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

MINT_MOUSE
θ value	8.99809 (rank : 287)	NC score	0.053194 (rank : 232)
Query Neighborhood Hits	305	Target Neighborhood Hits	1514	Shared Neighborhood Hits	132
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYLK_MOUSE
θ value	8.99809 (rank : 288)	NC score	0.014657 (rank : 383)
Query Neighborhood Hits	305	Target Neighborhood Hits	1489	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NANO1_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.013323 (rank : 388)
Query Neighborhood Hits	305	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WY3, Q3UTS9, Q8BIJ9	Gene names	Nanos1, Nos
Domain Architecture
Description	Nanos homolog 1.

NCF4_MOUSE
θ value	8.99809 (rank : 290)	NC score	0.112613 (rank : 34)
Query Neighborhood Hits	305	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NFAC3_HUMAN
θ value	8.99809 (rank : 291)	NC score	0.009376 (rank : 407)
Query Neighborhood Hits	305	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

PAPPA_HUMAN
θ value	8.99809 (rank : 292)	NC score	0.005918 (rank : 420)
Query Neighborhood Hits	305	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCLO_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.080672 (rank : 106)
Query Neighborhood Hits	305	Target Neighborhood Hits	2046	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PITM1_HUMAN
θ value	8.99809 (rank : 294)	NC score	0.008905 (rank : 409)
Query Neighborhood Hits	305	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

PK1L1_HUMAN
θ value	8.99809 (rank : 295)	NC score	0.033150 (rank : 299)
Query Neighborhood Hits	305	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PRR13_HUMAN
θ value	8.99809 (rank : 296)	NC score	0.048072 (rank : 259)
Query Neighborhood Hits	305	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PSL1_HUMAN
θ value	8.99809 (rank : 297)	NC score	0.063943 (rank : 177)
Query Neighborhood Hits	305	Target Neighborhood Hits	650	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PTN23_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.024550 (rank : 340)
Query Neighborhood Hits	305	Target Neighborhood Hits	646	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RUNX2_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.021027 (rank : 355)
Query Neighborhood Hits	305	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

SF3B1_MOUSE
θ value	8.99809 (rank : 300)	NC score	0.046202 (rank : 263)
Query Neighborhood Hits	305	Target Neighborhood Hits	352	Shared Neighborhood Hits	55
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SMCA2_HUMAN
θ value	8.99809 (rank : 301)	NC score	0.022000 (rank : 350)
Query Neighborhood Hits	305	Target Neighborhood Hits	503	Shared Neighborhood Hits	46
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	8.99809 (rank : 302)	NC score	0.027450 (rank : 324)
Query Neighborhood Hits	305	Target Neighborhood Hits	597	Shared Neighborhood Hits	61
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SYTL1_MOUSE
θ value	8.99809 (rank : 303)	NC score	0.012991 (rank : 391)
Query Neighborhood Hits	305	Target Neighborhood Hits	314	Shared Neighborhood Hits	28
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TAB3_HUMAN
θ value	8.99809 (rank : 304)	NC score	0.027312 (rank : 326)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

VINEX_HUMAN
θ value	8.99809 (rank : 305)	NC score	0.112381 (rank : 36)
Query Neighborhood Hits	305	Target Neighborhood Hits	270	Shared Neighborhood Hits	71
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ABI1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.082520 (rank : 100)
Query Neighborhood Hits	305	Target Neighborhood Hits	257	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.084759 (rank : 95)
Query Neighborhood Hits	305	Target Neighborhood Hits	246	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.108200 (rank : 37)
Query Neighborhood Hits	305	Target Neighborhood Hits	350	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.102813 (rank : 50)
Query Neighborhood Hits	305	Target Neighborhood Hits	266	Shared Neighborhood Hits	69
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.061073 (rank : 189)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.063758 (rank : 178)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AHI1_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.075014 (rank : 126)
Query Neighborhood Hits	305	Target Neighborhood Hits	537	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ALEX_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.052521 (rank : 237)
Query Neighborhood Hits	305	Target Neighborhood Hits	361	Shared Neighborhood Hits	70
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARHG4_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.064450 (rank : 173)
Query Neighborhood Hits	305	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.052884 (rank : 234)
Query Neighborhood Hits	305	Target Neighborhood Hits	185	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG6_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.070200 (rank : 146)
Query Neighborhood Hits	305	Target Neighborhood Hits	376	Shared Neighborhood Hits	62
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.071621 (rank : 143)
Query Neighborhood Hits	305	Target Neighborhood Hits	394	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARI1A_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.062078 (rank : 186)
Query Neighborhood Hits	305	Target Neighborhood Hits	787	Shared Neighborhood Hits	104
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ASPP1_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.063742 (rank : 179)
Query Neighborhood Hits	305	Target Neighborhood Hits	956	Shared Neighborhood Hits	96
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.078564 (rank : 116)
Query Neighborhood Hits	305	Target Neighborhood Hits	1244	Shared Neighborhood Hits	138
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.050085 (rank : 254)
Query Neighborhood Hits	305	Target Neighborhood Hits	1156	Shared Neighborhood Hits	102
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATX2L_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.051243 (rank : 246)
Query Neighborhood Hits	305	Target Neighborhood Hits	443	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BASP_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.051324 (rank : 244)
Query Neighborhood Hits	305	Target Neighborhood Hits	321	Shared Neighborhood Hits	46
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.050402 (rank : 252)
Query Neighborhood Hits	305	Target Neighborhood Hits	260	Shared Neighborhood Hits	43
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BCL9_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.064348 (rank : 174)
Query Neighborhood Hits	305	Target Neighborhood Hits	1008	Shared Neighborhood Hits	128
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.057777 (rank : 207)
Query Neighborhood Hits	305	Target Neighborhood Hits	770	Shared Neighborhood Hits	120
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CASL_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.088498 (rank : 82)
Query Neighborhood Hits	305	Target Neighborhood Hits	259	Shared Neighborhood Hits	72
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.093021 (rank : 64)
Query Neighborhood Hits	305	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CBP_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.054853 (rank : 223)
Query Neighborhood Hits	305	Target Neighborhood Hits	941	Shared Neighborhood Hits	116
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.074294 (rank : 129)
Query Neighborhood Hits	305	Target Neighborhood Hits	1051	Shared Neighborhood Hits	124
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CD2AP_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.093476 (rank : 63)
Query Neighborhood Hits	305	Target Neighborhood Hits	315	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.107155 (rank : 40)
Query Neighborhood Hits	305	Target Neighborhood Hits	336	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CO039_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.060627 (rank : 192)
Query Neighborhood Hits	305	Target Neighborhood Hits	445	Shared Neighborhood Hits	76
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CRKL_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.094904 (rank : 61)
Query Neighborhood Hits	305	Target Neighborhood Hits	313	Shared Neighborhood Hits	72
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.088415 (rank : 84)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	67
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.087739 (rank : 87)
Query Neighborhood Hits	305	Target Neighborhood Hits	308	Shared Neighborhood Hits	65
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.088928 (rank : 79)
Query Neighborhood Hits	305	Target Neighborhood Hits	314	Shared Neighborhood Hits	69
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CS016_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.052324 (rank : 239)
Query Neighborhood Hits	305	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CT032_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.092542 (rank : 66)
Query Neighborhood Hits	305	Target Neighborhood Hits	235	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CTDP1_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.063001 (rank : 184)
Query Neighborhood Hits	305	Target Neighborhood Hits	416	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DBNL_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.077831 (rank : 119)
Query Neighborhood Hits	305	Target Neighborhood Hits	244	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.074244 (rank : 130)
Query Neighborhood Hits	305	Target Neighborhood Hits	306	Shared Neighborhood Hits	58
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DDEF1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.052935 (rank : 233)
Query Neighborhood Hits	305	Target Neighborhood Hits	592	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DIDO1_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.058524 (rank : 203)
Query Neighborhood Hits	305	Target Neighborhood Hits	960	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ENAH_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.053501 (rank : 231)
Query Neighborhood Hits	305	Target Neighborhood Hits	919	Shared Neighborhood Hits	87
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ES8L3_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.053741 (rank : 227)
Query Neighborhood Hits	305	Target Neighborhood Hits	206	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FNBP2_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.061818 (rank : 187)
Query Neighborhood Hits	305	Target Neighborhood Hits	432	Shared Neighborhood Hits	65
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GRIN1_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.063058 (rank : 182)
Query Neighborhood Hits	305	Target Neighborhood Hits	681	Shared Neighborhood Hits	98
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GRIN1_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.052138 (rank : 240)
Query Neighborhood Hits	305	Target Neighborhood Hits	337	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HCLS1_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.106469 (rank : 43)
Query Neighborhood Hits	305	Target Neighborhood Hits	329	Shared Neighborhood Hits	86
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

JPH2_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.051065 (rank : 247)
Query Neighborhood Hits	305	Target Neighborhood Hits	639	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K1802_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.068889 (rank : 152)
Query Neighborhood Hits	305	Target Neighborhood Hits	1596	Shared Neighborhood Hits	136
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LASP1_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.080521 (rank : 107)
Query Neighborhood Hits	305	Target Neighborhood Hits	297	Shared Neighborhood Hits	57
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MAGE1_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.079437 (rank : 113)
Query Neighborhood Hits	305	Target Neighborhood Hits	1389	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MARCS_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.053764 (rank : 226)
Query Neighborhood Hits	305	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MDC1_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.092052 (rank : 67)
Query Neighborhood Hits	305	Target Neighborhood Hits	1446	Shared Neighborhood Hits	134
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MISS_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.051278 (rank : 245)
Query Neighborhood Hits	305	Target Neighborhood Hits	444	Shared Neighborhood Hits	78
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL2_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.066745 (rank : 160)
Query Neighborhood Hits	305	Target Neighborhood Hits	1788	Shared Neighborhood Hits	141
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.096415 (rank : 59)
Query Neighborhood Hits	305	Target Neighborhood Hits	975	Shared Neighborhood Hits	132
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC7_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.069976 (rank : 147)
Query Neighborhood Hits	305	Target Neighborhood Hits	538	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCF1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.079622 (rank : 112)
Query Neighborhood Hits	305	Target Neighborhood Hits	198	Shared Neighborhood Hits	59
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.078699 (rank : 115)
Query Neighborhood Hits	305	Target Neighborhood Hits	198	Shared Neighborhood Hits	57
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCK2_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.094801 (rank : 62)
Query Neighborhood Hits	305	Target Neighborhood Hits	310	Shared Neighborhood Hits	66
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NEBL_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.069009 (rank : 151)
Query Neighborhood Hits	305	Target Neighborhood Hits	457	Shared Neighborhood Hits	61
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.059732 (rank : 196)
Query Neighborhood Hits	305	Target Neighborhood Hits	420	Shared Neighborhood Hits	60
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NOXO1_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.056459 (rank : 217)
Query Neighborhood Hits	305	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.073603 (rank : 131)
Query Neighborhood Hits	305	Target Neighborhood Hits	288	Shared Neighborhood Hits	59
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NSD1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.050456 (rank : 249)
Query Neighborhood Hits	305	Target Neighborhood Hits	472	Shared Neighborhood Hits	49
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PACN1_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.065779 (rank : 166)
Query Neighborhood Hits	305	Target Neighborhood Hits	320	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.066159 (rank : 165)
Query Neighborhood Hits	305	Target Neighborhood Hits	283	Shared Neighborhood Hits	61
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN2_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.065048 (rank : 171)
Query Neighborhood Hits	305	Target Neighborhood Hits	339	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.065082 (rank : 169)
Query Neighborhood Hits	305	Target Neighborhood Hits	382	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.063058 (rank : 183)
Query Neighborhood Hits	305	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.068217 (rank : 154)
Query Neighborhood Hits	305	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PCQAP_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.065394 (rank : 168)
Query Neighborhood Hits	305	Target Neighborhood Hits	506	Shared Neighborhood Hits	62
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PEX13_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.057705 (rank : 208)
Query Neighborhood Hits	305	Target Neighborhood Hits	128	Shared Neighborhood Hits	45
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.057674 (rank : 209)
Query Neighborhood Hits	305	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PLCG2_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.050435 (rank : 250)
Query Neighborhood Hits	305	Target Neighborhood Hits	280	Shared Neighborhood Hits	53
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PPIP1_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.107028 (rank : 41)
Query Neighborhood Hits	305	Target Neighborhood Hits	377	Shared Neighborhood Hits	67
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.069931 (rank : 148)
Query Neighborhood Hits	305	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.085195 (rank : 91)
Query Neighborhood Hits	305	Target Neighborhood Hits	385	Shared Neighborhood Hits	74
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.085166 (rank : 92)
Query Neighborhood Hits	305	Target Neighborhood Hits	347	Shared Neighborhood Hits	71
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.068174 (rank : 155)
Query Neighborhood Hits	305	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRR12_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.052543 (rank : 235)
Query Neighborhood Hits	305	Target Neighborhood Hits	460	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRRT3_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.089907 (rank : 75)
Query Neighborhood Hits	305	Target Neighborhood Hits	998	Shared Neighborhood Hits	139
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RERE_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.068249 (rank : 153)
Query Neighborhood Hits	305	Target Neighborhood Hits	779	Shared Neighborhood Hits	89
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RGS3_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.083919 (rank : 98)
Query Neighborhood Hits	305	Target Neighborhood Hits	1621	Shared Neighborhood Hits	167
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SET1A_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.054407 (rank : 224)
Query Neighborhood Hits	305	Target Neighborhood Hits	690	Shared Neighborhood Hits	64
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SH3G2_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.096374 (rank : 60)
Query Neighborhood Hits	305	Target Neighborhood Hits	324	Shared Neighborhood Hits	66
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G3_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.101042 (rank : 52)
Query Neighborhood Hits	305	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G3_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.103308 (rank : 49)
Query Neighborhood Hits	305	Target Neighborhood Hits	236	Shared Neighborhood Hits	62
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3K1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.088541 (rank : 81)
Query Neighborhood Hits	305	Target Neighborhood Hits	341	Shared Neighborhood Hits	74
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.089437 (rank : 77)
Query Neighborhood Hits	305	Target Neighborhood Hits	332	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SHAN2_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.057022 (rank : 213)
Query Neighborhood Hits	305	Target Neighborhood Hits	446	Shared Neighborhood Hits	81
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SHLB1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.057616 (rank : 210)
Query Neighborhood Hits	305	Target Neighborhood Hits	96	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SHLB1_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.057427 (rank : 211)
Query Neighborhood Hits	305	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SHLB2_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.063702 (rank : 180)
Query Neighborhood Hits	305	Target Neighborhood Hits	86	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.065045 (rank : 172)
Query Neighborhood Hits	305	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SNX18_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.050433 (rank : 251)
Query Neighborhood Hits	305	Target Neighborhood Hits	207	Shared Neighborhood Hits	55
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.050392 (rank : 253)
Query Neighborhood Hits	305	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SON_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.071712 (rank : 142)
Query Neighborhood Hits	305	Target Neighborhood Hits	1568	Shared Neighborhood Hits	148
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.053737 (rank : 228)
Query Neighborhood Hits	305	Target Neighborhood Hits	957	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRBS1_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.089246 (rank : 78)
Query Neighborhood Hits	305	Target Neighborhood Hits	396	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.106580 (rank : 42)
Query Neighborhood Hits	305	Target Neighborhood Hits	409	Shared Neighborhood Hits	84
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.097776 (rank : 57)
Query Neighborhood Hits	305	Target Neighborhood Hits	269	Shared Neighborhood Hits	64
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.097338 (rank : 58)
Query Neighborhood Hits	305	Target Neighborhood Hits	292	Shared Neighborhood Hits	70
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRGP1_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.066658 (rank : 161)
Query Neighborhood Hits	305	Target Neighborhood Hits	390	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.071230 (rank : 145)
Query Neighborhood Hits	305	Target Neighborhood Hits	331	Shared Neighborhood Hits	58
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.072081 (rank : 140)
Query Neighborhood Hits	305	Target Neighborhood Hits	324	Shared Neighborhood Hits	60
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRRM2_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.062498 (rank : 185)
Query Neighborhood Hits	305	Target Neighborhood Hits	1296	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SSBP4_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.057265 (rank : 212)
Query Neighborhood Hits	305	Target Neighborhood Hits	753	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STAC3_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.067817 (rank : 157)
Query Neighborhood Hits	305	Target Neighborhood Hits	228	Shared Neighborhood Hits	57
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.067729 (rank : 158)
Query Neighborhood Hits	305	Target Neighborhood Hits	232	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.073048 (rank : 133)
Query Neighborhood Hits	305	Target Neighborhood Hits	276	Shared Neighborhood Hits	64
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.072493 (rank : 135)
Query Neighborhood Hits	305	Target Neighborhood Hits	268	Shared Neighborhood Hits	65
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.090978 (rank : 71)
Query Neighborhood Hits	305	Target Neighborhood Hits	271	Shared Neighborhood Hits	68
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.088192 (rank : 85)
Query Neighborhood Hits	305	Target Neighborhood Hits	273	Shared Neighborhood Hits	69
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.084579 (rank : 96)
Query Neighborhood Hits	305	Target Neighborhood Hits	288	Shared Neighborhood Hits	68
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

T22D4_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.056631 (rank : 216)
Query Neighborhood Hits	305	Target Neighborhood Hits	403	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TARSH_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.055677 (rank : 219)
Query Neighborhood Hits	305	Target Neighborhood Hits	768	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

VAV2_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.059115 (rank : 201)
Query Neighborhood Hits	305	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.059082 (rank : 202)
Query Neighborhood Hits	305	Target Neighborhood Hits	456	Shared Neighborhood Hits	63
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.053718 (rank : 229)
Query Neighborhood Hits	305	Target Neighborhood Hits	398	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.052542 (rank : 236)
Query Neighborhood Hits	305	Target Neighborhood Hits	404	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.060041 (rank : 195)
Query Neighborhood Hits	305	Target Neighborhood Hits	452	Shared Neighborhood Hits	64
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.059518 (rank : 198)
Query Neighborhood Hits	305	Target Neighborhood Hits	430	Shared Neighborhood Hits	64
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

WASIP_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.069348 (rank : 150)
Query Neighborhood Hits	305	Target Neighborhood Hits	458	Shared Neighborhood Hits	69
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WIRE_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.050957 (rank : 248)
Query Neighborhood Hits	305	Target Neighborhood Hits	329	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

Hits sorted by NC score

RUSC2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	305	Target Neighborhood Hits	305	Shared Neighborhood Hits	305
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC2_HUMAN
NC score	0.934883 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	305	Target Neighborhood Hits	205	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC1_HUMAN
NC score	0.686593 (rank : 3)	θ value	6.13105e-57 (rank : 3)
Query Neighborhood Hits	305	Target Neighborhood Hits	226	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC1_MOUSE
NC score	0.657656 (rank : 4)	θ value	2.86122e-38 (rank : 4)
Query Neighborhood Hits	305	Target Neighborhood Hits	206	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

EFS_MOUSE
NC score	0.214013 (rank : 5)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	305	Target Neighborhood Hits	389	Shared Neighborhood Hits	96
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

NCF2_HUMAN
NC score	0.196307 (rank : 6)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	305	Target Neighborhood Hits	229	Shared Neighborhood Hits	61
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

EFS_HUMAN
NC score	0.193901 (rank : 7)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	305	Target Neighborhood Hits	348	Shared Neighborhood Hits	94
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

PPIP1_HUMAN
NC score	0.150261 (rank : 8)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	305	Target Neighborhood Hits	389	Shared Neighborhood Hits	67
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

GRAP_HUMAN
NC score	0.149617 (rank : 9)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	72
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP2_MOUSE
NC score	0.143917 (rank : 10)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	305	Target Neighborhood Hits	297	Shared Neighborhood Hits	70
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP2_HUMAN
NC score	0.142891 (rank : 11)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	305	Target Neighborhood Hits	304	Shared Neighborhood Hits	74
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

BCAR1_MOUSE
NC score	0.140670 (rank : 12)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	305	Target Neighborhood Hits	438	Shared Neighborhood Hits	103
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

GRAP_MOUSE
NC score	0.140670 (rank : 13)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	305	Target Neighborhood Hits	309	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

BCAR1_HUMAN
NC score	0.138472 (rank : 14)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	305	Target Neighborhood Hits	554	Shared Neighborhood Hits	114
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

GPS2_HUMAN
NC score	0.136192 (rank : 15)	θ value	0.00298849 (rank : 8)
Query Neighborhood Hits	305	Target Neighborhood Hits	459	Shared Neighborhood Hits	51
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

SH3G1_HUMAN
NC score	0.135837 (rank : 16)	θ value	0.0193708 (rank : 16)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	65
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

GRB2_HUMAN
NC score	0.135464 (rank : 17)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	305	Target Neighborhood Hits	310	Shared Neighborhood Hits	69
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.135264 (rank : 18)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	305	Target Neighborhood Hits	312	Shared Neighborhood Hits	69
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

RHG04_HUMAN
NC score	0.133593 (rank : 19)	θ value	0.00020696 (rank : 5)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

OGFR_HUMAN
NC score	0.130284 (rank : 20)	θ value	0.0252991 (rank : 18)
Query Neighborhood Hits	305	Target Neighborhood Hits	1582	Shared Neighborhood Hits	175
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NCF4_HUMAN
NC score	0.130007 (rank : 21)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	305	Target Neighborhood Hits	161	Shared Neighborhood Hits	54
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

HCLS1_HUMAN
NC score	0.127549 (rank : 22)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	305	Target Neighborhood Hits	358	Shared Neighborhood Hits	92
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

VINEX_MOUSE
NC score	0.123830 (rank : 23)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	305	Target Neighborhood Hits	286	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

NCK1_HUMAN
NC score	0.120795 (rank : 24)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	305	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

DNMBP_HUMAN
NC score	0.119648 (rank : 25)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	305	Target Neighborhood Hits	413	Shared Neighborhood Hits	69
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SRRM1_MOUSE
NC score	0.117355 (rank : 26)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	305	Target Neighborhood Hits	966	Shared Neighborhood Hits	114
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAF4_HUMAN
NC score	0.116584 (rank : 27)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	305	Target Neighborhood Hits	687	Shared Neighborhood Hits	87
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ITSN2_HUMAN
NC score	0.115913 (rank : 28)	θ value	0.0193708 (rank : 14)
Query Neighborhood Hits	305	Target Neighborhood Hits	1173	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN1_MOUSE
NC score	0.114990 (rank : 29)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	305	Target Neighborhood Hits	1669	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NCOA6_MOUSE
NC score	0.114682 (rank : 30)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	305	Target Neighborhood Hits	1076	Shared Neighborhood Hits	145
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SH3G1_MOUSE
NC score	0.114494 (rank : 31)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	305	Target Neighborhood Hits	291	Shared Neighborhood Hits	66
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

ITSN1_HUMAN
NC score	0.114447 (rank : 32)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	305	Target Neighborhood Hits	1757	Shared Neighborhood Hits	125
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

BSN_MOUSE
NC score	0.113282 (rank : 33)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	305	Target Neighborhood Hits	2057	Shared Neighborhood Hits	184
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NCF4_MOUSE
NC score	0.112613 (rank : 34)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	305	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SH3G2_MOUSE
NC score	0.112544 (rank : 35)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	305	Target Neighborhood Hits	319	Shared Neighborhood Hits	69
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

VINEX_HUMAN
NC score	0.112381 (rank : 36)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	305	Target Neighborhood Hits	270	Shared Neighborhood Hits	71
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ABI2_HUMAN
NC score	0.108200 (rank : 37)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	305	Target Neighborhood Hits	350	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ITSN2_MOUSE
NC score	0.108156 (rank : 38)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	305	Target Neighborhood Hits	1371	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

CK024_HUMAN
NC score	0.107499 (rank : 39)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	305	Target Neighborhood Hits	408	Shared Neighborhood Hits	73
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CD2AP_MOUSE
NC score	0.107155 (rank : 40)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	305	Target Neighborhood Hits	336	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

PPIP1_MOUSE
NC score	0.107028 (rank : 41)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	305	Target Neighborhood Hits	377	Shared Neighborhood Hits	67
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SRBS1_MOUSE
NC score	0.106580 (rank : 42)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	305	Target Neighborhood Hits	409	Shared Neighborhood Hits	84
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

HCLS1_MOUSE
NC score	0.106469 (rank : 43)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	305	Target Neighborhood Hits	329	Shared Neighborhood Hits	86
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

NPHP1_MOUSE
NC score	0.104462 (rank : 44)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	305	Target Neighborhood Hits	267	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

ATN1_HUMAN
NC score	0.104457 (rank : 45)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	305	Target Neighborhood Hits	676	Shared Neighborhood Hits	91
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SELPL_MOUSE
NC score	0.104147 (rank : 46)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	305	Target Neighborhood Hits	588	Shared Neighborhood Hits	95
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

TCGAP_HUMAN
NC score	0.103756 (rank : 47)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	305	Target Neighborhood Hits	872	Shared Neighborhood Hits	142
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

IASPP_MOUSE
NC score	0.103509 (rank : 48)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	305	Target Neighborhood Hits	1024	Shared Neighborhood Hits	148
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SH3G3_MOUSE
NC score	0.103308 (rank : 49)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	305	Target Neighborhood Hits	236	Shared Neighborhood Hits	62
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

ABI2_MOUSE
NC score	0.102813 (rank : 50)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	305	Target Neighborhood Hits	266	Shared Neighborhood Hits	69
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

STAM2_MOUSE
NC score	0.102086 (rank : 51)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	305	Target Neighborhood Hits	285	Shared Neighborhood Hits	69
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SH3G3_HUMAN
NC score	0.101042 (rank : 52)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	305	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

NCOA6_HUMAN
NC score	0.100156 (rank : 53)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	305	Target Neighborhood Hits	1202	Shared Neighborhood Hits	153
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

DNMBP_MOUSE
NC score	0.099888 (rank : 54)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	305	Target Neighborhood Hits	435	Shared Neighborhood Hits	76
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

MLL3_HUMAN
NC score	0.098475 (rank : 55)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	305	Target Neighborhood Hits	1644	Shared Neighborhood Hits	142
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BSN_HUMAN
NC score	0.098093 (rank : 56)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	305	Target Neighborhood Hits	1537	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SRC8_HUMAN
NC score	0.097776 (rank : 57)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	305	Target Neighborhood Hits	269	Shared Neighborhood Hits	64
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
NC score	0.097338 (rank : 58)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	305	Target Neighborhood Hits	292	Shared Neighborhood Hits	70
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

MUC1_HUMAN
NC score	0.096415 (rank : 59)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	305	Target Neighborhood Hits	975	Shared Neighborhood Hits	132
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SH3G2_HUMAN
NC score	0.096374 (rank : 60)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	305	Target Neighborhood Hits	324	Shared Neighborhood Hits	66
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

CRKL_HUMAN
NC score	0.094904 (rank : 61)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	305	Target Neighborhood Hits	313	Shared Neighborhood Hits	72
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

NCK2_HUMAN
NC score	0.094801 (rank : 62)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	305	Target Neighborhood Hits	310	Shared Neighborhood Hits	66
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CD2AP_HUMAN
NC score	0.093476 (rank : 63)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	305	Target Neighborhood Hits	315	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CASL_MOUSE
NC score	0.093021 (rank : 64)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	305	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

LASP1_HUMAN
NC score	0.092756 (rank : 65)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	305	Target Neighborhood Hits	293	Shared Neighborhood Hits	56
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

CT032_HUMAN
NC score	0.092542 (rank : 66)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	305	Target Neighborhood Hits	235	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

MDC1_HUMAN
NC score	0.092052 (rank : 67)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	305	Target Neighborhood Hits	1446	Shared Neighborhood Hits	134
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PRB3_HUMAN
NC score	0.091968 (rank : 68)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	305	Target Neighborhood Hits	318	Shared Neighborhood Hits	61
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

NACAM_MOUSE
NC score	0.091653 (rank : 69)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	305	Target Neighborhood Hits	1866	Shared Neighborhood Hits	154
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

IASPP_HUMAN
NC score	0.091376 (rank : 70)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	305	Target Neighborhood Hits	688	Shared Neighborhood Hits	112
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

STAM1_HUMAN
NC score	0.090978 (rank : 71)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	305	Target Neighborhood Hits	271	Shared Neighborhood Hits	68
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

AHI1_MOUSE
NC score	0.090272 (rank : 72)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	305	Target Neighborhood Hits	496	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

OSTF1_HUMAN
NC score	0.090219 (rank : 73)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	305	Target Neighborhood Hits	466	Shared Neighborhood Hits	68
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ARHG7_MOUSE
NC score	0.089929 (rank : 74)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	305	Target Neighborhood Hits	396	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

PRRT3_HUMAN
NC score	0.089907 (rank : 75)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	305	Target Neighborhood Hits	998	Shared Neighborhood Hits	139
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MDC1_MOUSE
NC score	0.089689 (rank : 76)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	305	Target Neighborhood Hits	998	Shared Neighborhood Hits	114
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SH3K1_MOUSE
NC score	0.089437 (rank : 77)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	305	Target Neighborhood Hits	332	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SRBS1_HUMAN
NC score	0.089246 (rank : 78)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	305	Target Neighborhood Hits	396	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CRK_MOUSE
NC score	0.088928 (rank : 79)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	305	Target Neighborhood Hits	314	Shared Neighborhood Hits	69
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

SYN1_MOUSE
NC score	0.088556 (rank : 80)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	305	Target Neighborhood Hits	363	Shared Neighborhood Hits	78
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SH3K1_HUMAN
NC score	0.088541 (rank : 81)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	305	Target Neighborhood Hits	341	Shared Neighborhood Hits	74
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

CASL_HUMAN
NC score	0.088498 (rank : 82)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	305	Target Neighborhood Hits	259	Shared Neighborhood Hits	72
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

PCQAP_HUMAN
NC score	0.088440 (rank : 83)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	305	Target Neighborhood Hits	549	Shared Neighborhood Hits	58
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

CRKL_MOUSE
NC score	0.088415 (rank : 84)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	67
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

STAM1_MOUSE
NC score	0.088192 (rank : 85)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	305	Target Neighborhood Hits	273	Shared Neighborhood Hits	69
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TARA_HUMAN
NC score	0.088028 (rank : 86)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	305	Target Neighborhood Hits	1626	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CRK_HUMAN
NC score	0.087739 (rank : 87)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	305	Target Neighborhood Hits	308	Shared Neighborhood Hits	65
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

MLL3_MOUSE
NC score	0.087298 (rank : 88)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	305	Target Neighborhood Hits	1399	Shared Neighborhood Hits	125
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PCLO_MOUSE
NC score	0.087163 (rank : 89)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	305	Target Neighborhood Hits	2275	Shared Neighborhood Hits	185
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

OSTF1_MOUSE
NC score	0.085690 (rank : 90)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	305	Target Neighborhood Hits	467	Shared Neighborhood Hits	68
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PRP1_HUMAN
NC score	0.085195 (rank : 91)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	305	Target Neighborhood Hits	385	Shared Neighborhood Hits	74
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
NC score	0.085166 (rank : 92)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	305	Target Neighborhood Hits	347	Shared Neighborhood Hits	71
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SRRM2_MOUSE
NC score	0.084869 (rank : 93)	θ value	4.03905 (rank : 218)
Query Neighborhood Hits	305	Target Neighborhood Hits	1470	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WASIP_MOUSE
NC score	0.084786 (rank : 94)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	305	Target Neighborhood Hits	392	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ABI1_MOUSE
NC score	0.084759 (rank : 95)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	305	Target Neighborhood Hits	246	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

STAM2_HUMAN
NC score	0.084579 (rank : 96)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	305	Target Neighborhood Hits	288	Shared Neighborhood Hits	68
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

SYN1_HUMAN
NC score	0.084505 (rank : 97)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	305	Target Neighborhood Hits	419	Shared Neighborhood Hits	81
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

RGS3_MOUSE
NC score	0.083919 (rank : 98)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	305	Target Neighborhood Hits	1621	Shared Neighborhood Hits	167
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SRRM1_HUMAN
NC score	0.083671 (rank : 99)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	305	Target Neighborhood Hits	690	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ABI1_HUMAN
NC score	0.082520 (rank : 100)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	305	Target Neighborhood Hits	257	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

GSCR1_HUMAN
NC score	0.082225 (rank : 101)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	305	Target Neighborhood Hits	674	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

BAT2_HUMAN
NC score	0.082089 (rank : 102)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	305	Target Neighborhood Hits	931	Shared Neighborhood Hits	111
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ARHG9_HUMAN
NC score	0.081404 (rank : 103)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	305	Target Neighborhood Hits	235	Shared Neighborhood Hits	60
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG7_HUMAN
NC score	0.081177 (rank : 104)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	305	Target Neighborhood Hits	347	Shared Neighborhood Hits	63
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG9_MOUSE
NC score	0.081119 (rank : 105)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	305	Target Neighborhood Hits	234	Shared Neighborhood Hits	61
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

PCLO_HUMAN
NC score	0.080672 (rank : 106)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	305	Target Neighborhood Hits	2046	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

LASP1_MOUSE
NC score	0.080521 (rank : 107)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	305	Target Neighborhood Hits	297	Shared Neighborhood Hits	57
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

RERE_MOUSE
NC score	0.080301 (rank : 108)	θ value	0.0961366 (rank : 37)
Query Neighborhood Hits	305	Target Neighborhood Hits	785	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SPTA1_HUMAN
NC score	0.080241 (rank : 109)	θ value	0.0961366 (rank : 38)
Query Neighborhood Hits	305	Target Neighborhood Hits	748	Shared Neighborhood Hits	64
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TCGAP_MOUSE
NC score	0.080135 (rank : 110)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	305	Target Neighborhood Hits	409	Shared Neighborhood Hits	82
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BAT2_MOUSE
NC score	0.079641 (rank : 111)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	305	Target Neighborhood Hits	947	Shared Neighborhood Hits	121
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NCF1_HUMAN
NC score	0.079622 (rank : 112)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	305	Target Neighborhood Hits	198	Shared Neighborhood Hits	59
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

MAGE1_HUMAN
NC score	0.079437 (rank : 113)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	305	Target Neighborhood Hits	1389	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BAT3_MOUSE
NC score	0.079016 (rank : 114)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	305	Target Neighborhood Hits	518	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

NCF1_MOUSE
NC score	0.078699 (rank : 115)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	305	Target Neighborhood Hits	198	Shared Neighborhood Hits	57
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

ASPP1_MOUSE
NC score	0.078564 (rank : 116)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	305	Target Neighborhood Hits	1244	Shared Neighborhood Hits	138
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CIC_HUMAN
NC score	0.078380 (rank : 117)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	305	Target Neighborhood Hits	992	Shared Neighborhood Hits	133
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO039_HUMAN
NC score	0.078074 (rank : 118)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	305	Target Neighborhood Hits	264	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

DBNL_HUMAN
NC score	0.077831 (rank : 119)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	305	Target Neighborhood Hits	244	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

K1543_MOUSE
NC score	0.077792 (rank : 120)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	305	Target Neighborhood Hits	497	Shared Neighborhood Hits	71
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NFH_MOUSE
NC score	0.077367 (rank : 121)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	305	Target Neighborhood Hits	2247	Shared Neighborhood Hits	169
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MARCS_MOUSE
NC score	0.077110 (rank : 122)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	38
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

ZAR1_MOUSE
NC score	0.076733 (rank : 123)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	305	Target Neighborhood Hits	254	Shared Neighborhood Hits	45
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

MUCDL_HUMAN
NC score	0.076607 (rank : 124)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	305	Target Neighborhood Hits	777	Shared Neighborhood Hits	120
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ANM2_HUMAN
NC score	0.075956 (rank : 125)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	305	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

AHI1_HUMAN
NC score	0.075014 (rank : 126)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	305	Target Neighborhood Hits	537	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ATX2_MOUSE
NC score	0.074656 (rank : 127)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	305	Target Neighborhood Hits	445	Shared Neighborhood Hits	69
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

ARI1B_HUMAN
NC score	0.074298 (rank : 128)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	305	Target Neighborhood Hits	567	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CBP_MOUSE
NC score	0.074294 (rank : 129)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	305	Target Neighborhood Hits	1051	Shared Neighborhood Hits	124
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DBNL_MOUSE
NC score	0.074244 (rank : 130)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	305	Target Neighborhood Hits	306	Shared Neighborhood Hits	58
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

NPHP1_HUMAN
NC score	0.073603 (rank : 131)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	305	Target Neighborhood Hits	288	Shared Neighborhood Hits	59
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

DDEF2_MOUSE
NC score	0.073168 (rank : 132)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	305	Target Neighborhood Hits	625	Shared Neighborhood Hits	85
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

STAC_HUMAN
NC score	0.073048 (rank : 133)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	305	Target Neighborhood Hits	276	Shared Neighborhood Hits	64
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

MYCB2_MOUSE
NC score	0.072631 (rank : 134)	θ value	0.00102713 (rank : 6)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

STAC_MOUSE
NC score	0.072493 (rank : 135)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	305	Target Neighborhood Hits	268	Shared Neighborhood Hits	65
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

PDZD2_HUMAN
NC score	0.072424 (rank : 136)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	305	Target Neighborhood Hits	772	Shared Neighborhood Hits	91
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

BAT3_HUMAN
NC score	0.072419 (rank : 137)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	305	Target Neighborhood Hits	490	Shared Neighborhood Hits	78
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

SPTA2_HUMAN
NC score	0.072331 (rank : 138)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	305	Target Neighborhood Hits	888	Shared Neighborhood Hits	73
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ANM2_MOUSE
NC score	0.072159 (rank : 139)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	305	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

SRGP2_MOUSE
NC score	0.072081 (rank : 140)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	305	Target Neighborhood Hits	324	Shared Neighborhood Hits	60
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

MKL1_MOUSE
NC score	0.072033 (rank : 141)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	305	Target Neighborhood Hits	667	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SON_HUMAN
NC score	0.071712 (rank : 142)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	305	Target Neighborhood Hits	1568	Shared Neighborhood Hits	148
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ARHG6_MOUSE
NC score	0.071621 (rank : 143)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	305	Target Neighborhood Hits	394	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

SAPS1_HUMAN
NC score	0.071299 (rank : 144)	θ value	0.279714 (rank : 67)
Query Neighborhood Hits	305	Target Neighborhood Hits	704	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SRGP2_HUMAN
NC score	0.071230 (rank : 145)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	305	Target Neighborhood Hits	331	Shared Neighborhood Hits	58
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

ARHG6_HUMAN
NC score	0.070200 (rank : 146)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	305	Target Neighborhood Hits	376	Shared Neighborhood Hits	62
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

MUC7_HUMAN
NC score	0.069976 (rank : 147)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	305	Target Neighborhood Hits	538	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PRB4S_HUMAN
NC score	0.069931 (rank : 148)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	305	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

K1802_HUMAN
NC score	0.069412 (rank : 149)	θ value	0.00298849 (rank : 9)
Query Neighborhood Hits	305	Target Neighborhood Hits	1378	Shared Neighborhood Hits	113
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WASIP_HUMAN
NC score	0.069348 (rank : 150)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	305	Target Neighborhood Hits	458	Shared Neighborhood Hits	69
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

NEBL_HUMAN
NC score	0.069009 (rank : 151)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	305	Target Neighborhood Hits	457	Shared Neighborhood Hits	61
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

K1802_MOUSE
NC score	0.068889 (rank : 152)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	305	Target Neighborhood Hits	1596	Shared Neighborhood Hits	136
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RERE_HUMAN
NC score	0.068249 (rank : 153)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	305	Target Neighborhood Hits	779	Shared Neighborhood Hits	89
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

PACN3_MOUSE
NC score	0.068217 (rank : 154)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	305	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PRP5_HUMAN
NC score	0.068174 (rank : 155)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	305	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

SPTA1_MOUSE
NC score	0.067915 (rank : 156)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	305	Target Neighborhood Hits	675	Shared Neighborhood Hits	65
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

STAC3_HUMAN
NC score	0.067817 (rank : 157)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	305	Target Neighborhood Hits	228	Shared Neighborhood Hits	57
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
NC score	0.067729 (rank : 158)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	305	Target Neighborhood Hits	232	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

EP300_HUMAN
NC score	0.066966 (rank : 159)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	305	Target Neighborhood Hits	821	Shared Neighborhood Hits	99
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MLL2_HUMAN
NC score	0.066745 (rank : 160)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	305	Target Neighborhood Hits	1788	Shared Neighborhood Hits	141
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SRGP1_HUMAN
NC score	0.066658 (rank : 161)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	305	Target Neighborhood Hits	390	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RANB3_HUMAN
NC score	0.066520 (rank : 162)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	305	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

SC24C_HUMAN
NC score	0.066270 (rank : 163)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	305	Target Neighborhood Hits	662	Shared Neighborhood Hits	99
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

AKTS1_MOUSE
NC score	0.066221 (rank : 164)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	305	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D1F4	Gene names	Akt1s1, Pras
Domain Architecture	No domain graphic available
Description	Proline-rich AKT1 substrate 1 (Proline-rich AKT substrate).

PACN1_MOUSE
NC score	0.066159 (rank : 165)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	305	Target Neighborhood Hits	283	Shared Neighborhood Hits	61
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_HUMAN
NC score	0.065779 (rank : 166)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	305	Target Neighborhood Hits	320	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

DDEF2_HUMAN
NC score	0.065585 (rank : 167)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	305	Target Neighborhood Hits	599	Shared Neighborhood Hits	89
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PCQAP_MOUSE
NC score	0.065394 (rank : 168)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	305	Target Neighborhood Hits	506	Shared Neighborhood Hits	62
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PACN2_MOUSE
NC score	0.065082 (rank : 169)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	305	Target Neighborhood Hits	382	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SYP2L_HUMAN
NC score	0.065049 (rank : 170)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	305	Target Neighborhood Hits	400	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PACN2_HUMAN
NC score	0.065048 (rank : 171)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	305	Target Neighborhood Hits	339	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SHLB2_MOUSE
NC score	0.065045 (rank : 172)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	305	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

ARHG4_HUMAN
NC score	0.064450 (rank : 173)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	305	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

BCL9_HUMAN
NC score	0.064348 (rank : 174)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	305	Target Neighborhood Hits	1008	Shared Neighborhood Hits	128
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

EWS_HUMAN
NC score	0.064269 (rank : 175)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	305	Target Neighborhood Hits	249	Shared Neighborhood Hits	29
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

GGN_HUMAN
NC score	0.064040 (rank : 176)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	305	Target Neighborhood Hits	269	Shared Neighborhood Hits	53
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PSL1_HUMAN
NC score	0.063943 (rank : 177)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	305	Target Neighborhood Hits	650	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

ABI3_MOUSE
NC score	0.063758 (rank : 178)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ASPP1_HUMAN
NC score	0.063742 (rank : 179)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	305	Target Neighborhood Hits	956	Shared Neighborhood Hits	96
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

SHLB2_HUMAN
NC score	0.063702 (rank : 180)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	305	Target Neighborhood Hits	86	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

MLL4_HUMAN
NC score	0.063699 (rank : 181)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	305	Target Neighborhood Hits	722	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

GRIN1_HUMAN
NC score	0.063058 (rank : 182)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	305	Target Neighborhood Hits	681	Shared Neighborhood Hits	98
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PACN3_HUMAN
NC score	0.063058 (rank : 183)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	305	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

CTDP1_HUMAN
NC score	0.063001 (rank : 184)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	305	Target Neighborhood Hits	416	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

SRRM2_HUMAN
NC score	0.062498 (rank : 185)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	305	Target Neighborhood Hits	1296	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ARI1A_HUMAN
NC score	0.062078 (rank : 186)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	305	Target Neighborhood Hits	787	Shared Neighborhood Hits	104
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

FNBP2_HUMAN
NC score	0.061818 (rank : 187)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	305	Target Neighborhood Hits	432	Shared Neighborhood Hits	65
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

PRG4_HUMAN
NC score	0.061253 (rank : 188)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	305	Target Neighborhood Hits	764	Shared Neighborhood Hits	72
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ABI3_HUMAN
NC score	0.061073 (rank : 189)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

BAG3_MOUSE
NC score	0.060836 (rank : 190)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	305	Target Neighborhood Hits	513	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

SNPC4_HUMAN
NC score	0.060715 (rank : 191)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	305	Target Neighborhood Hits	589	Shared Neighborhood Hits	89
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CO039_MOUSE
NC score	0.060627 (rank : 192)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	305	Target Neighborhood Hits	445	Shared Neighborhood Hits	76
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SHAN1_HUMAN
NC score	0.060345 (rank : 193)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	305	Target Neighborhood Hits	1041	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TGON2_HUMAN
NC score	0.060287 (rank : 194)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	305	Target Neighborhood Hits	1037	Shared Neighborhood Hits	91
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

VAV_HUMAN
NC score	0.060041 (rank : 195)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	305	Target Neighborhood Hits	452	Shared Neighborhood Hits	64
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

NEBU_HUMAN
NC score	0.059732 (rank : 196)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	305	Target Neighborhood Hits	420	Shared Neighborhood Hits	60
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

DOT1L_HUMAN
NC score	0.059700 (rank : 197)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	305	Target Neighborhood Hits	660	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

VAV_MOUSE
NC score	0.059518 (rank : 198)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	305	Target Neighborhood Hits	430	Shared Neighborhood Hits	64
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

CO002_HUMAN
NC score	0.059288 (rank : 199)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	305	Target Neighborhood Hits	387	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

EWS_MOUSE
NC score	0.059184 (rank : 200)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	305	Target Neighborhood Hits	271	Shared Neighborhood Hits	33
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

VAV2_HUMAN
NC score	0.059115 (rank : 201)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	305	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
NC score	0.059082 (rank : 202)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	305	Target Neighborhood Hits	456	Shared Neighborhood Hits	63
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

DIDO1_HUMAN
NC score	0.058524 (rank : 203)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	305	Target Neighborhood Hits	960	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

LRC56_HUMAN
NC score	0.058309 (rank : 204)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	305	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

CAC1G_HUMAN
NC score	0.058030 (rank : 205)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	305	Target Neighborhood Hits	587	Shared Neighborhood Hits	88
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

RGS3_HUMAN
NC score	0.057891 (rank : 206)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	305	Target Neighborhood Hits	1375	Shared Neighborhood Hits	147
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

BCL9_MOUSE
NC score	0.057777 (rank : 207)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	305	Target Neighborhood Hits	770	Shared Neighborhood Hits	120
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

PEX13_HUMAN
NC score	0.057705 (rank : 208)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	305	Target Neighborhood Hits	128	Shared Neighborhood Hits	45
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
NC score	0.057674 (rank : 209)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	305	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

SHLB1_HUMAN
NC score	0.057616 (rank : 210)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	305	Target Neighborhood Hits	96	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SHLB1_MOUSE
NC score	0.057427 (rank : 211)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	305	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SSBP4_HUMAN
NC score	0.057265 (rank : 212)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	305	Target Neighborhood Hits	753	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SHAN2_MOUSE
NC score	0.057022 (rank : 213)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	305	Target Neighborhood Hits	446	Shared Neighborhood Hits	81
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

CABIN_HUMAN
NC score	0.056998 (rank : 214)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	305	Target Neighborhood Hits	490	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

ES8L3_MOUSE
NC score	0.056783 (rank : 215)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	55
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

T22D4_HUMAN
NC score	0.056631 (rank : 216)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	305	Target Neighborhood Hits	403	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

NOXO1_MOUSE
NC score	0.056459 (rank : 217)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	305	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

ZAR1_HUMAN
NC score	0.056377 (rank : 218)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	305	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

TARSH_HUMAN
NC score	0.055677 (rank : 219)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	305	Target Neighborhood Hits	768	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CTND2_HUMAN
NC score	0.055652 (rank : 220)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	305	Target Neighborhood Hits	333	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PRG4_MOUSE
NC score	0.055509 (rank : 221)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	305	Target Neighborhood Hits	624	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

R3HD2_MOUSE
NC score	0.055061 (rank : 222)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	305	Target Neighborhood Hits	397	Shared Neighborhood Hits	69
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

CBP_HUMAN
NC score	0.054853 (rank : 223)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	305	Target Neighborhood Hits	941	Shared Neighborhood Hits	116
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SET1A_HUMAN
NC score	0.054407 (rank : 224)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	305	Target Neighborhood Hits	690	Shared Neighborhood Hits	64
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

RECQ5_HUMAN
NC score	0.054160 (rank : 225)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	305	Target Neighborhood Hits	390	Shared Neighborhood Hits	67
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

MARCS_HUMAN
NC score	0.053764 (rank : 226)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	305	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

ES8L3_HUMAN
NC score	0.053741 (rank : 227)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	305	Target Neighborhood Hits	206	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

SON_MOUSE
NC score	0.053737 (rank : 228)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	305	Target Neighborhood Hits	957	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

VAV3_HUMAN
NC score	0.053718 (rank : 229)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	305	Target Neighborhood Hits	398	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

RIMB1_HUMAN
NC score	0.053687 (rank : 230)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	305	Target Neighborhood Hits	1479	Shared Neighborhood Hits	132
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ENAH_MOUSE
NC score	0.053501 (rank : 231)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	305	Target Neighborhood Hits	919	Shared Neighborhood Hits	87
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MINT_MOUSE
NC score	0.053194 (rank : 232)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	305	Target Neighborhood Hits	1514	Shared Neighborhood Hits	132
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DDEF1_MOUSE
NC score	0.052935 (rank : 233)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	305	Target Neighborhood Hits	592	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

ARHG4_MOUSE
NC score	0.052884 (rank : 234)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	305	Target Neighborhood Hits	185	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

PRR12_HUMAN
NC score	0.052543 (rank : 235)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	305	Target Neighborhood Hits	460	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

VAV3_MOUSE
NC score	0.052542 (rank : 236)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	305	Target Neighborhood Hits	404	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ALEX_HUMAN
NC score	0.052521 (rank : 237)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	305	Target Neighborhood Hits	361	Shared Neighborhood Hits	70
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

PO121_MOUSE
NC score	0.052367 (rank : 238)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	305	Target Neighborhood Hits	345	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

CS016_HUMAN
NC score	0.052324 (rank : 239)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	305	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

GRIN1_MOUSE
NC score	0.052138 (rank : 240)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	305	Target Neighborhood Hits	337	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CIC_MOUSE
NC score	0.052086 (rank : 241)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	305	Target Neighborhood Hits	742	Shared Neighborhood Hits	99
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CDN1C_HUMAN
NC score	0.052012 (rank : 242)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	32
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

JIP1_MOUSE
NC score	0.051846 (rank : 243)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	305	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

BASP_HUMAN
NC score	0.051324 (rank : 244)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	305	Target Neighborhood Hits	321	Shared Neighborhood Hits	46
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MISS_MOUSE
NC score	0.051278 (rank : 245)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	305	Target Neighborhood Hits	444	Shared Neighborhood Hits	78
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

ATX2L_HUMAN
NC score	0.051243 (rank : 246)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	305	Target Neighborhood Hits	443	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

JPH2_HUMAN
NC score	0.051065 (rank : 247)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	305	Target Neighborhood Hits	639	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

WIRE_HUMAN
NC score	0.050957 (rank : 248)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	305	Target Neighborhood Hits	329	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

NSD1_MOUSE
NC score	0.050456 (rank : 249)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	305	Target Neighborhood Hits	472	Shared Neighborhood Hits	49
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PLCG2_HUMAN
NC score	0.050435 (rank : 250)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	305	Target Neighborhood Hits	280	Shared Neighborhood Hits	53
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

SNX18_HUMAN
NC score	0.050433 (rank : 251)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	305	Target Neighborhood Hits	207	Shared Neighborhood Hits	55
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

BASP_MOUSE
NC score	0.050402 (rank : 252)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	305	Target Neighborhood Hits	260	Shared Neighborhood Hits	43
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SNX18_MOUSE
NC score	0.050392 (rank : 253)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	305	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

ASPP2_HUMAN
NC score	0.050085 (rank : 254)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	305	Target Neighborhood Hits	1156	Shared Neighborhood Hits	102
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

JIP3_HUMAN
NC score	0.049957 (rank : 255)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	305	Target Neighborhood Hits	1039	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

GCNL2_MOUSE
NC score	0.048697 (rank : 256)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	305	Target Neighborhood Hits	146	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

NSD1_HUMAN
NC score	0.048573 (rank : 257)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	305	Target Neighborhood Hits	427	Shared Neighborhood Hits	56
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NCOR2_MOUSE
NC score	0.048281 (rank : 258)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	305	Target Neighborhood Hits	790	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PRR13_HUMAN
NC score	0.048072 (rank : 259)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	305	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

EPS8_MOUSE
NC score	0.048054 (rank : 260)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	305	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

3BP1_HUMAN
NC score	0.046950 (rank : 261)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	305	Target Neighborhood Hits	376	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GCNL2_HUMAN
NC score	0.046267 (rank : 262)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	305	Target Neighborhood Hits	159	Shared Neighborhood Hits	33
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

SF3B1_MOUSE
NC score	0.046202 (rank : 263)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	305	Target Neighborhood Hits	352	Shared Neighborhood Hits	55
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SMG7_MOUSE
NC score	0.045837 (rank : 264)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	305	Target Neighborhood Hits	113	Shared Neighborhood Hits	22
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

CSKI2_MOUSE
NC score	0.044620 (rank : 265)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	305	Target Neighborhood Hits	812	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

EP400_HUMAN
NC score	0.043616 (rank : 266)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	305	Target Neighborhood Hits	556	Shared Neighborhood Hits	69
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

CCNK_MOUSE
NC score	0.043088 (rank : 267)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	305	Target Neighborhood Hits	350	Shared Neighborhood Hits	53
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

DACT1_HUMAN
NC score	0.042908 (rank : 268)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	305	Target Neighborhood Hits	228	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

WASP_HUMAN
NC score	0.042849 (rank : 269)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	305	Target Neighborhood Hits	195	Shared Neighborhood Hits	39
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

RRBP1_MOUSE
NC score	0.042835 (rank : 270)	θ value	0.0193708 (rank : 15)
Query Neighborhood Hits	305	Target Neighborhood Hits	1650	Shared Neighborhood Hits	70
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CTND2_MOUSE
NC score	0.041830 (rank : 271)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

FYN_MOUSE
NC score	0.040967 (rank : 272)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	305	Target Neighborhood Hits	1073	Shared Neighborhood Hits	75
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

CO5A2_HUMAN
NC score	0.040727 (rank : 273)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	305	Target Neighborhood Hits	760	Shared Neighborhood Hits	84
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

FYN_HUMAN
NC score	0.040471 (rank : 274)	θ value	0.279714 (rank : 61)
Query Neighborhood Hits	305	Target Neighborhood Hits	1078	Shared Neighborhood Hits	75
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

CO1A2_MOUSE
NC score	0.039937 (rank : 275)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	305	Target Neighborhood Hits	388	Shared Neighborhood Hits	50
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

SHAN2_HUMAN
NC score	0.039317 (rank : 276)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	305	Target Neighborhood Hits	346	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

LDB3_MOUSE
NC score	0.039242 (rank : 277)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	305	Target Neighborhood Hits	510	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

UBXD1_HUMAN
NC score	0.039012 (rank : 278)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	305	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZV1, Q96AH1, Q96IK9, Q9BZV0	Gene names	UBXD1, UBXDC2
Domain Architecture
Description	UBX domain-containing protein 1.

USH1C_MOUSE
NC score	0.038658 (rank : 279)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	305	Target Neighborhood Hits	557	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

HCN2_MOUSE
NC score	0.038262 (rank : 280)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	305	Target Neighborhood Hits	278	Shared Neighborhood Hits	55
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_MOUSE
NC score	0.038230 (rank : 281)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	305	Target Neighborhood Hits	284	Shared Neighborhood Hits	55
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

TCF19_MOUSE
NC score	0.038004 (rank : 282)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	305	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

CSKI2_HUMAN
NC score	0.037736 (rank : 283)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	305	Target Neighborhood Hits	747	Shared Neighborhood Hits	91
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CO1A1_HUMAN
NC score	0.036961 (rank : 284)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	305	Target Neighborhood Hits	475	Shared Neighborhood Hits	58
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_MOUSE
NC score	0.036548 (rank : 285)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	305	Target Neighborhood Hits	466	Shared Neighborhood Hits	60
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

GP152_MOUSE
NC score	0.036516 (rank : 286)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	305	Target Neighborhood Hits	607	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

CSKI1_MOUSE
NC score	0.036511 (rank : 287)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	305	Target Neighborhood Hits	1031	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TCF20_HUMAN
NC score	0.035859 (rank : 288)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	305	Target Neighborhood Hits	323	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CO2A1_HUMAN
NC score	0.035801 (rank : 289)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	305	Target Neighborhood Hits	486	Shared Neighborhood Hits	67
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

ABL1_MOUSE
NC score	0.035778 (rank : 290)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	305	Target Neighborhood Hits	1178	Shared Neighborhood Hits	93
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

MYO1E_HUMAN
NC score	0.035742 (rank : 291)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	305	Target Neighborhood Hits	293	Shared Neighborhood Hits	64
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

ABL1_HUMAN
NC score	0.035702 (rank : 292)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	305	Target Neighborhood Hits	1220	Shared Neighborhood Hits	95
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

MILK2_HUMAN
NC score	0.035151 (rank : 293)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	305	Target Neighborhood Hits	457	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

TACC3_HUMAN
NC score	0.034976 (rank : 294)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	305	Target Neighborhood Hits	779	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

HCN4_HUMAN
NC score	0.034796 (rank : 295)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	305	Target Neighborhood Hits	303	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

LEUK_HUMAN
NC score	0.034328 (rank : 296)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	305	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

CEBPE_HUMAN
NC score	0.033910 (rank : 297)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	305	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

NCOR1_MOUSE
NC score	0.033800 (rank : 298)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	305	Target Neighborhood Hits	521	Shared Neighborhood Hits	44
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PK1L1_HUMAN
NC score	0.033150 (rank : 299)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	305	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

SMRC2_HUMAN
NC score	0.033104 (rank : 300)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	305	Target Neighborhood Hits	499	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

RP3A_HUMAN
NC score	0.032930 (rank : 301)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	305	Target Neighborhood Hits	305	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TBCD3_HUMAN
NC score	0.032866 (rank : 302)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	305	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

LIMD1_MOUSE
NC score	0.032834 (rank : 303)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	305	Target Neighborhood Hits	291	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

ARI5B_HUMAN
NC score	0.032706 (rank : 304)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	305	Target Neighborhood Hits	328	Shared Neighborhood Hits	25
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

COBA1_HUMAN
NC score	0.032699 (rank : 305)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	305	Target Neighborhood Hits	491	Shared Neighborhood Hits	61
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

PKHA4_HUMAN
NC score	0.032456 (rank : 306)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	305	Target Neighborhood Hits	283	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

COBA1_MOUSE
NC score	0.032061 (rank : 307)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	305	Target Neighborhood Hits	487	Shared Neighborhood Hits	59
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

GCC1_MOUSE
NC score	0.031091 (rank : 308)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	305	Target Neighborhood Hits	777	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

TXK_MOUSE
NC score	0.030989 (rank : 309)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	305	Target Neighborhood Hits	980	Shared Neighborhood Hits	62
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

ABL2_HUMAN
NC score	0.030967 (rank : 310)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	305	Target Neighborhood Hits	1045	Shared Neighborhood Hits	61
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

BEGIN_HUMAN
NC score	0.030848 (rank : 311)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	305	Target Neighborhood Hits	454	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

TAF6_HUMAN
NC score	0.030848 (rank : 312)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	305	Target Neighborhood Hits	127	Shared Neighborhood Hits	34
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

CO5A3_HUMAN
NC score	0.030035 (rank : 313)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	305	Target Neighborhood Hits	433	Shared Neighborhood Hits	43
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

HORN_HUMAN
NC score	0.029952 (rank : 314)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	305	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

CAC1H_HUMAN
NC score	0.029313 (rank : 315)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	305	Target Neighborhood Hits	307	Shared Neighborhood Hits	45
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

REV1_MOUSE
NC score	0.029095 (rank : 316)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	305	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

ARI5B_MOUSE
NC score	0.028600 (rank : 317)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	305	Target Neighborhood Hits	158	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

EHMT2_MOUSE
NC score	0.028449 (rank : 318)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	305	Target Neighborhood Hits	750	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

AATK_HUMAN
NC score	0.028338 (rank : 319)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	305	Target Neighborhood Hits	1243	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

B4GT1_HUMAN
NC score	0.027969 (rank : 320)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	21
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

MATK_HUMAN
NC score	0.027604 (rank : 321)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	305	Target Neighborhood Hits	954	Shared Neighborhood Hits	45
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

HAP1_MOUSE
NC score	0.027594 (rank : 322)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	305	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

LCK_HUMAN
NC score	0.027497 (rank : 323)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	305	Target Neighborhood Hits	987	Shared Neighborhood Hits	52
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

SMCA4_HUMAN
NC score	0.027450 (rank : 324)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	305	Target Neighborhood Hits	597	Shared Neighborhood Hits	61
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

USBP1_HUMAN
NC score	0.027354 (rank : 325)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	305	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

TAB3_HUMAN
NC score	0.027312 (rank : 326)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

DOCK4_MOUSE
NC score	0.027194 (rank : 327)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	305	Target Neighborhood Hits	210	Shared Neighborhood Hits	46
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

YBOX2_HUMAN
NC score	0.026311 (rank : 328)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	305	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2T7, Q8N4P0	Gene names	YBX2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (Contrin) (MSY2 homolog).

RUNX1_MOUSE
NC score	0.026227 (rank : 329)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	305	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

STK10_HUMAN
NC score	0.025984 (rank : 330)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	305	Target Neighborhood Hits	1921	Shared Neighborhood Hits	75
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

DOCK4_HUMAN
NC score	0.025908 (rank : 331)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	305	Target Neighborhood Hits	237	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

WNK2_HUMAN
NC score	0.025895 (rank : 332)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	305	Target Neighborhood Hits	1407	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

YBOX2_MOUSE
NC score	0.025610 (rank : 333)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	305	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

BCOR_HUMAN
NC score	0.025602 (rank : 334)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	305	Target Neighborhood Hits	609	Shared Neighborhood Hits	46
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

PHLPP_HUMAN
NC score	0.025584 (rank : 335)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	305	Target Neighborhood Hits	604	Shared Neighborhood Hits	72
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

TIF1G_HUMAN
NC score	0.025451 (rank : 336)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	305	Target Neighborhood Hits	410	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

JUNB_MOUSE
NC score	0.025422 (rank : 337)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	305	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

MAST4_HUMAN
NC score	0.025042 (rank : 338)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	305	Target Neighborhood Hits	1804	Shared Neighborhood Hits	139
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

LBXCO_HUMAN
NC score	0.024845 (rank : 339)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	305	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

PTN23_HUMAN
NC score	0.024550 (rank : 340)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	305	Target Neighborhood Hits	646	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SRMS_MOUSE
NC score	0.024481 (rank : 341)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	305	Target Neighborhood Hits	964	Shared Neighborhood Hits	47
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

CEP68_HUMAN
NC score	0.024469 (rank : 342)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	305	Target Neighborhood Hits	128	Shared Neighborhood Hits	21
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

PEF1_HUMAN
NC score	0.023930 (rank : 343)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	305	Target Neighborhood Hits	135	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

DMWD_MOUSE
NC score	0.023762 (rank : 344)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	305	Target Neighborhood Hits	282	Shared Neighborhood Hits	18
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

GAK_HUMAN
NC score	0.023402 (rank : 345)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	305	Target Neighborhood Hits	1028	Shared Neighborhood Hits	52
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

FOG1_HUMAN
NC score	0.023394 (rank : 346)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	305	Target Neighborhood Hits	981	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

SPEG_HUMAN
NC score	0.023299 (rank : 347)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	305	Target Neighborhood Hits	1762	Shared Neighborhood Hits	111
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PININ_MOUSE
NC score	0.022325 (rank : 348)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	305	Target Neighborhood Hits	777	Shared Neighborhood Hits	37
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

AFF3_HUMAN
NC score	0.022059 (rank : 349)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	305	Target Neighborhood Hits	190	Shared Neighborhood Hits	29
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

SMCA2_HUMAN
NC score	0.022000 (rank : 350)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	305	Target Neighborhood Hits	503	Shared Neighborhood Hits	46
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

FOXJ2_MOUSE
NC score	0.021972 (rank : 351)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	305	Target Neighborhood Hits	151	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ES18	Gene names	Foxj2, Fhx
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

FOXJ2_HUMAN
NC score	0.021902 (rank : 352)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	305	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

ARP5_MOUSE
NC score	0.021712 (rank : 353)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	305	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

PRDM2_HUMAN
NC score	0.021384 (rank : 354)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	305	Target Neighborhood Hits	1135	Shared Neighborhood Hits	69
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

RUNX2_HUMAN
NC score	0.021027 (rank : 355)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	305	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

BORG5_MOUSE
NC score	0.020976 (rank : 356)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	305	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	Q91W92, Q9D8M1	Gene names	Cdc42ep1, Borg5, Cep1
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5).

MK07_MOUSE
NC score	0.020632 (rank : 357)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	305	Target Neighborhood Hits	1054	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

ZN414_HUMAN
NC score	0.020541 (rank : 358)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	305	Target Neighborhood Hits	548	Shared Neighborhood Hits	29
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

RAIN_HUMAN
NC score	0.020230 (rank : 359)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	305	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

MEGF9_HUMAN
NC score	0.020181 (rank : 360)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	305	Target Neighborhood Hits	557	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MK07_HUMAN
NC score	0.019637 (rank : 361)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	305	Target Neighborhood Hits	1087	Shared Neighborhood Hits	64
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

ULK1_MOUSE
NC score	0.019362 (rank : 362)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	305	Target Neighborhood Hits	1214	Shared Neighborhood Hits	90
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ONEC2_MOUSE
NC score	0.019231 (rank : 363)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	305	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q6XBJ3	Gene names	Onecut2, Oc2
Domain Architecture	No domain graphic available
Description	One cut domain family member 2 (Transcription factor ONECUT-2) (OC-2).

APBA3_HUMAN
NC score	0.018811 (rank : 364)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	305	Target Neighborhood Hits	201	Shared Neighborhood Hits	18
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ADA2B_MOUSE
NC score	0.018618 (rank : 365)	θ value	0.00298849 (rank : 7)
Query Neighborhood Hits	305	Target Neighborhood Hits	891	Shared Neighborhood Hits	8
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

SCN8A_HUMAN
NC score	0.018521 (rank : 366)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	305	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

GRASP_HUMAN
NC score	0.018383 (rank : 367)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	305	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

KCNH6_HUMAN
NC score	0.018001 (rank : 368)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	305	Target Neighborhood Hits	222	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

SCN8A_MOUSE
NC score	0.017940 (rank : 369)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	305	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

BAI1_HUMAN
NC score	0.017633 (rank : 370)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	305	Target Neighborhood Hits	375	Shared Neighborhood Hits	32
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TBX21_MOUSE
NC score	0.017211 (rank : 371)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	305	Target Neighborhood Hits	116	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

SRTD2_HUMAN
NC score	0.017194 (rank : 372)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	305	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

POLK_MOUSE
NC score	0.017123 (rank : 373)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	305	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

SMBP2_MOUSE
NC score	0.017061 (rank : 374)	θ value	4.03905 (rank : 216)
Query Neighborhood Hits	305	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

TENN_MOUSE
NC score	0.016297 (rank : 375)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	305	Target Neighborhood Hits	484	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

BAI1_MOUSE
NC score	0.015982 (rank : 376)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	305	Target Neighborhood Hits	340	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

HAND1_MOUSE
NC score	0.015709 (rank : 377)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	305	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

HXA3_MOUSE
NC score	0.015424 (rank : 378)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	305	Target Neighborhood Hits	558	Shared Neighborhood Hits	55
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HXD3_HUMAN
NC score	0.015085 (rank : 379)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	305	Target Neighborhood Hits	433	Shared Neighborhood Hits	31
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

PAX5_MOUSE
NC score	0.015085 (rank : 380)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	305	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PAX5_HUMAN
NC score	0.014988 (rank : 381)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	305	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	Q02548, O75933	Gene names	PAX5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

TOB1_MOUSE
NC score	0.014735 (rank : 382)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	305	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q61471	Gene names	Tob1, Tob, Trob
Domain Architecture
Description	Tob1 protein (Transducer of erbB-2 1).

MYLK_MOUSE
NC score	0.014657 (rank : 383)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	305	Target Neighborhood Hits	1489	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

CHD9_HUMAN
NC score	0.014563 (rank : 384)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	305	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

DUS8_HUMAN
NC score	0.014437 (rank : 385)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	305	Target Neighborhood Hits	161	Shared Neighborhood Hits	26
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

LAP4_HUMAN
NC score	0.014306 (rank : 386)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	305	Target Neighborhood Hits	608	Shared Neighborhood Hits	36
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

CHST8_MOUSE
NC score	0.013645 (rank : 387)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	305	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQ86, Q76EC6, Q80XD4	Gene names	Chst8
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 8 (EC 2.8.2.-) (N-acetylgalactosamine-4- O-sulfotransferase 1) (GalNAc-4-O-sulfotransferase 1) (GalNAc-4-ST1) (GalNAc4ST-1).

NANO1_MOUSE
NC score	0.013323 (rank : 388)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	305	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WY3, Q3UTS9, Q8BIJ9	Gene names	Nanos1, Nos
Domain Architecture
Description	Nanos homolog 1.

HXD3_MOUSE
NC score	0.013269 (rank : 389)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	305	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

ATS14_HUMAN
NC score	0.013065 (rank : 390)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	305	Target Neighborhood Hits	382	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

SYTL1_MOUSE
NC score	0.012991 (rank : 391)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	305	Target Neighborhood Hits	314	Shared Neighborhood Hits	28
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

CSPG3_MOUSE
NC score	0.012860 (rank : 392)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	305	Target Neighborhood Hits	657	Shared Neighborhood Hits	38
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

B4GT1_MOUSE
NC score	0.012685 (rank : 393)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	305	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

FOXM1_HUMAN
NC score	0.012651 (rank : 394)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	305	Target Neighborhood Hits	167	Shared Neighborhood Hits	18
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

LSR_HUMAN
NC score	0.012534 (rank : 395)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	305	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

PO2F1_MOUSE
NC score	0.012454 (rank : 396)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	305	Target Neighborhood Hits	408	Shared Neighborhood Hits	26
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

KIF1C_HUMAN
NC score	0.012379 (rank : 397)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	305	Target Neighborhood Hits	128	Shared Neighborhood Hits	8
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

JHD2C_HUMAN
NC score	0.011282 (rank : 398)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	305	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

POLS_HUMAN
NC score	0.011226 (rank : 399)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	305	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q5XG87, O43289, Q9Y6C1	Gene names	POLS, TRF4
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7) (Topoisomerase-related function protein 4-1) (TRF4-1) (LAK-1) (DNA polymerase kappa).

ACH10_HUMAN
NC score	0.011218 (rank : 400)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	305	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZZ6	Gene names	CHRNA10, NACHRA10
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-10 precursor (Nicotinic acetylcholine receptor subunit alpha 10) (NACHR alpha 10).

UBR2_MOUSE
NC score	0.011053 (rank : 401)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	305	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

ZN219_HUMAN
NC score	0.010759 (rank : 402)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	305	Target Neighborhood Hits	876	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

HXB3_MOUSE
NC score	0.010691 (rank : 403)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	305	Target Neighborhood Hits	493	Shared Neighborhood Hits	32
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

M3K1_MOUSE
NC score	0.010535 (rank : 404)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	305	Target Neighborhood Hits	952	Shared Neighborhood Hits	35
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

RXRB_HUMAN
NC score	0.009868 (rank : 405)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	305	Target Neighborhood Hits	280	Shared Neighborhood Hits	36
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

KLF13_HUMAN
NC score	0.009475 (rank : 406)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	305	Target Neighborhood Hits	739	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

NFAC3_HUMAN
NC score	0.009376 (rank : 407)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	305	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

SLIK1_MOUSE
NC score	0.009126 (rank : 408)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	305	Target Neighborhood Hits	333	Shared Neighborhood Hits	11
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

PITM1_HUMAN
NC score	0.008905 (rank : 409)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	305	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

FSTL4_HUMAN
NC score	0.008900 (rank : 410)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	305	Target Neighborhood Hits	344	Shared Neighborhood Hits	5
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

SEM5A_MOUSE
NC score	0.008613 (rank : 411)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	305	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

E41LB_MOUSE
NC score	0.008575 (rank : 412)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	305	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

SCND2_HUMAN
NC score	0.008289 (rank : 413)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	305	Target Neighborhood Hits	86	Shared Neighborhood Hits	11
SwissProt Accessions	Q9GZW5, Q9H9G1	Gene names	SCAND2
Domain Architecture
Description	SCAN domain-containing protein 2.

E41LB_HUMAN
NC score	0.007977 (rank : 414)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	305	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

ETV4_HUMAN
NC score	0.007873 (rank : 415)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	305	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

GLIS3_HUMAN
NC score	0.007671 (rank : 416)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	305	Target Neighborhood Hits	758	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

EGR1_MOUSE
NC score	0.006804 (rank : 417)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	305	Target Neighborhood Hits	816	Shared Neighborhood Hits	33
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

PHX2A_HUMAN
NC score	0.006208 (rank : 418)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	305	Target Neighborhood Hits	345	Shared Neighborhood Hits	10
SwissProt Accessions	O14813, Q8IVZ2	Gene names	PHOX2A, ARIX, PMX2A
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein).

K1C23_MOUSE
NC score	0.006101 (rank : 419)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	305	Target Neighborhood Hits	370	Shared Neighborhood Hits	12
SwissProt Accessions	Q99PS0	Gene names	Krt23, Haik1, Krt1-23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

PAPPA_HUMAN
NC score	0.005918 (rank : 420)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	305	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

BARH2_MOUSE
NC score	0.005703 (rank : 421)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	305	Target Neighborhood Hits	397	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VIB5, Q66L43	Gene names	Barhl2, Barh1, Mbh1
Domain Architecture	No domain graphic available
Description	BarH-like 2 homeobox protein (Bar-class homeodomain protein MBH1) (Homeobox protein B-H1).

OST3B_HUMAN
NC score	0.005525 (rank : 422)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	305	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

DNER_HUMAN
NC score	0.004855 (rank : 423)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	305	Target Neighborhood Hits	460	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

ZN592_MOUSE
NC score	0.004770 (rank : 424)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	305	Target Neighborhood Hits	768	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

SALL1_HUMAN
NC score	0.004430 (rank : 425)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	305	Target Neighborhood Hits	821	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

STAB1_HUMAN
NC score	0.003864 (rank : 426)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	305	Target Neighborhood Hits	546	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

PGBM_HUMAN
NC score	0.003141 (rank : 427)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	305	Target Neighborhood Hits	1113	Shared Neighborhood Hits	27
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

GLIS1_MOUSE
NC score	0.003069 (rank : 428)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	305	Target Neighborhood Hits	751	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).