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Network neighborhood for query Sequence : BCAR1_MOUSE

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BCAR1_MOUSE
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BCAR1_HUMAN
θ value	0 (rank : 1)	NC score	0.956575 (rank : 2)
Query Neighborhood Hits	438	Target Neighborhood Hits	554	Shared Neighborhood Hits	362
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	438	Target Neighborhood Hits	438	Shared Neighborhood Hits	438
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CASL_MOUSE
θ value	9.87422e-140 (rank : 3)	NC score	0.896636 (rank : 3)
Query Neighborhood Hits	438	Target Neighborhood Hits	225	Shared Neighborhood Hits	158
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CASL_HUMAN
θ value	5.07123e-136 (rank : 4)	NC score	0.890661 (rank : 4)
Query Neighborhood Hits	438	Target Neighborhood Hits	259	Shared Neighborhood Hits	165
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CT032_HUMAN
θ value	6.15952e-41 (rank : 5)	NC score	0.801408 (rank : 5)
Query Neighborhood Hits	438	Target Neighborhood Hits	235	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

EFS_HUMAN
θ value	2.59387e-31 (rank : 6)	NC score	0.740616 (rank : 6)
Query Neighborhood Hits	438	Target Neighborhood Hits	348	Shared Neighborhood Hits	196
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	2.68423e-28 (rank : 7)	NC score	0.732342 (rank : 7)
Query Neighborhood Hits	438	Target Neighborhood Hits	389	Shared Neighborhood Hits	213
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

IASPP_MOUSE
θ value	5.26297e-08 (rank : 8)	NC score	0.361344 (rank : 43)
Query Neighborhood Hits	438	Target Neighborhood Hits	1024	Shared Neighborhood Hits	276
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_HUMAN
θ value	1.99992e-07 (rank : 9)	NC score	0.367494 (rank : 39)
Query Neighborhood Hits	438	Target Neighborhood Hits	688	Shared Neighborhood Hits	214
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PPIP1_HUMAN
θ value	4.45536e-07 (rank : 10)	NC score	0.446344 (rank : 13)
Query Neighborhood Hits	438	Target Neighborhood Hits	389	Shared Neighborhood Hits	174
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SH3K1_MOUSE
θ value	9.92553e-07 (rank : 11)	NC score	0.476374 (rank : 10)
Query Neighborhood Hits	438	Target Neighborhood Hits	332	Shared Neighborhood Hits	174
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

ASPP1_HUMAN
θ value	1.29631e-06 (rank : 12)	NC score	0.307043 (rank : 75)
Query Neighborhood Hits	438	Target Neighborhood Hits	956	Shared Neighborhood Hits	195
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CD2AP_MOUSE
θ value	1.69304e-06 (rank : 13)	NC score	0.493287 (rank : 8)
Query Neighborhood Hits	438	Target Neighborhood Hits	336	Shared Neighborhood Hits	185
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

PPIP1_MOUSE
θ value	2.88788e-06 (rank : 14)	NC score	0.442027 (rank : 15)
Query Neighborhood Hits	438	Target Neighborhood Hits	377	Shared Neighborhood Hits	169
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

ASPP1_MOUSE
θ value	3.77169e-06 (rank : 15)	NC score	0.315472 (rank : 73)
Query Neighborhood Hits	438	Target Neighborhood Hits	1244	Shared Neighborhood Hits	268
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

SH3K1_HUMAN
θ value	4.92598e-06 (rank : 16)	NC score	0.473198 (rank : 11)
Query Neighborhood Hits	438	Target Neighborhood Hits	341	Shared Neighborhood Hits	170
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

PEX13_MOUSE
θ value	1.09739e-05 (rank : 17)	NC score	0.434689 (rank : 16)
Query Neighborhood Hits	438	Target Neighborhood Hits	126	Shared Neighborhood Hits	105
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

CD2AP_HUMAN
θ value	3.19293e-05 (rank : 18)	NC score	0.476777 (rank : 9)
Query Neighborhood Hits	438	Target Neighborhood Hits	315	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

MYO1F_HUMAN
θ value	3.19293e-05 (rank : 19)	NC score	0.198820 (rank : 120)
Query Neighborhood Hits	438	Target Neighborhood Hits	275	Shared Neighborhood Hits	167
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	3.19293e-05 (rank : 20)	NC score	0.197942 (rank : 121)
Query Neighborhood Hits	438	Target Neighborhood Hits	262	Shared Neighborhood Hits	161
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

PEX13_HUMAN
θ value	3.19293e-05 (rank : 21)	NC score	0.433092 (rank : 17)
Query Neighborhood Hits	438	Target Neighborhood Hits	128	Shared Neighborhood Hits	107
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

ITSN1_MOUSE
θ value	5.44631e-05 (rank : 22)	NC score	0.283942 (rank : 83)
Query Neighborhood Hits	438	Target Neighborhood Hits	1669	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

HCLS1_HUMAN
θ value	7.1131e-05 (rank : 23)	NC score	0.463584 (rank : 12)
Query Neighborhood Hits	438	Target Neighborhood Hits	358	Shared Neighborhood Hits	201
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ITSN2_MOUSE
θ value	7.1131e-05 (rank : 24)	NC score	0.273268 (rank : 86)
Query Neighborhood Hits	438	Target Neighborhood Hits	1371	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

M3K9_HUMAN
θ value	7.1131e-05 (rank : 25)	NC score	0.117988 (rank : 200)
Query Neighborhood Hits	438	Target Neighborhood Hits	1123	Shared Neighborhood Hits	185
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

ASPP2_HUMAN
θ value	9.29e-05 (rank : 26)	NC score	0.251803 (rank : 99)
Query Neighborhood Hits	438	Target Neighborhood Hits	1156	Shared Neighborhood Hits	207
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

M3KL4_HUMAN
θ value	9.29e-05 (rank : 27)	NC score	0.133002 (rank : 175)
Query Neighborhood Hits	438	Target Neighborhood Hits	1087	Shared Neighborhood Hits	169
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MGR1_HUMAN
θ value	9.29e-05 (rank : 28)	NC score	0.051053 (rank : 563)
Query Neighborhood Hits	438	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

M3K11_HUMAN
θ value	0.000121331 (rank : 29)	NC score	0.128531 (rank : 185)
Query Neighborhood Hits	438	Target Neighborhood Hits	1136	Shared Neighborhood Hits	198
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

ITSN2_HUMAN
θ value	0.000158464 (rank : 30)	NC score	0.289381 (rank : 81)
Query Neighborhood Hits	438	Target Neighborhood Hits	1173	Shared Neighborhood Hits	191
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

VAV_HUMAN
θ value	0.000158464 (rank : 31)	NC score	0.317178 (rank : 69)
Query Neighborhood Hits	438	Target Neighborhood Hits	452	Shared Neighborhood Hits	166
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ITSN1_HUMAN
θ value	0.00020696 (rank : 32)	NC score	0.281465 (rank : 84)
Query Neighborhood Hits	438	Target Neighborhood Hits	1757	Shared Neighborhood Hits	242
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NCK1_HUMAN
θ value	0.00020696 (rank : 33)	NC score	0.383095 (rank : 29)
Query Neighborhood Hits	438	Target Neighborhood Hits	312	Shared Neighborhood Hits	170
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

VAV_MOUSE
θ value	0.00020696 (rank : 34)	NC score	0.315826 (rank : 72)
Query Neighborhood Hits	438	Target Neighborhood Hits	430	Shared Neighborhood Hits	166
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ARHG7_HUMAN
θ value	0.000270298 (rank : 35)	NC score	0.363842 (rank : 42)
Query Neighborhood Hits	438	Target Neighborhood Hits	347	Shared Neighborhood Hits	170
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

SPTA2_HUMAN
θ value	0.000270298 (rank : 36)	NC score	0.189695 (rank : 124)
Query Neighborhood Hits	438	Target Neighborhood Hits	888	Shared Neighborhood Hits	166
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

MYO1E_HUMAN
θ value	0.00035302 (rank : 37)	NC score	0.183846 (rank : 130)
Query Neighborhood Hits	438	Target Neighborhood Hits	293	Shared Neighborhood Hits	167
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

TCGAP_HUMAN
θ value	0.00035302 (rank : 38)	NC score	0.225368 (rank : 109)
Query Neighborhood Hits	438	Target Neighborhood Hits	872	Shared Neighborhood Hits	251
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GRAP2_MOUSE
θ value	0.000461057 (rank : 39)	NC score	0.388502 (rank : 27)
Query Neighborhood Hits	438	Target Neighborhood Hits	297	Shared Neighborhood Hits	175
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRB2_HUMAN
θ value	0.000461057 (rank : 40)	NC score	0.383277 (rank : 28)
Query Neighborhood Hits	438	Target Neighborhood Hits	310	Shared Neighborhood Hits	172
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.000461057 (rank : 41)	NC score	0.382990 (rank : 30)
Query Neighborhood Hits	438	Target Neighborhood Hits	312	Shared Neighborhood Hits	172
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HCLS1_MOUSE
θ value	0.000461057 (rank : 42)	NC score	0.442069 (rank : 14)
Query Neighborhood Hits	438	Target Neighborhood Hits	329	Shared Neighborhood Hits	191
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

ATN1_HUMAN
θ value	0.000786445 (rank : 43)	NC score	0.159925 (rank : 141)
Query Neighborhood Hits	438	Target Neighborhood Hits	676	Shared Neighborhood Hits	112
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SH3G2_MOUSE
θ value	0.000786445 (rank : 44)	NC score	0.401984 (rank : 22)
Query Neighborhood Hits	438	Target Neighborhood Hits	319	Shared Neighborhood Hits	161
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

AHI1_HUMAN
θ value	0.00102713 (rank : 45)	NC score	0.299402 (rank : 80)
Query Neighborhood Hits	438	Target Neighborhood Hits	537	Shared Neighborhood Hits	168
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

SRC8_MOUSE
θ value	0.00102713 (rank : 46)	NC score	0.406028 (rank : 19)
Query Neighborhood Hits	438	Target Neighborhood Hits	292	Shared Neighborhood Hits	165
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SH3G2_HUMAN
θ value	0.00134147 (rank : 47)	NC score	0.393636 (rank : 25)
Query Neighborhood Hits	438	Target Neighborhood Hits	324	Shared Neighborhood Hits	158
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SRC8_HUMAN
θ value	0.00134147 (rank : 48)	NC score	0.405353 (rank : 20)
Query Neighborhood Hits	438	Target Neighborhood Hits	269	Shared Neighborhood Hits	163
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

ARHG7_MOUSE
θ value	0.00175202 (rank : 49)	NC score	0.355381 (rank : 48)
Query Neighborhood Hits	438	Target Neighborhood Hits	396	Shared Neighborhood Hits	165
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

GAK5_HUMAN
θ value	0.00175202 (rank : 50)	NC score	0.138881 (rank : 158)
Query Neighborhood Hits	438	Target Neighborhood Hits	429	Shared Neighborhood Hits	124
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GRAP2_HUMAN
θ value	0.00175202 (rank : 51)	NC score	0.376888 (rank : 34)
Query Neighborhood Hits	438	Target Neighborhood Hits	304	Shared Neighborhood Hits	176
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

RGS3_MOUSE
θ value	0.00175202 (rank : 52)	NC score	0.146016 (rank : 153)
Query Neighborhood Hits	438	Target Neighborhood Hits	1621	Shared Neighborhood Hits	230
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TCGAP_MOUSE
θ value	0.00175202 (rank : 53)	NC score	0.200804 (rank : 119)
Query Neighborhood Hits	438	Target Neighborhood Hits	409	Shared Neighborhood Hits	151
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GAK11_HUMAN
θ value	0.00228821 (rank : 54)	NC score	0.138075 (rank : 161)
Query Neighborhood Hits	438	Target Neighborhood Hits	409	Shared Neighborhood Hits	121
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	0.00228821 (rank : 55)	NC score	0.138010 (rank : 162)
Query Neighborhood Hits	438	Target Neighborhood Hits	406	Shared Neighborhood Hits	120
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	0.00228821 (rank : 56)	NC score	0.138217 (rank : 160)
Query Neighborhood Hits	438	Target Neighborhood Hits	415	Shared Neighborhood Hits	121
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ABI2_HUMAN
θ value	0.00298849 (rank : 57)	NC score	0.400013 (rank : 23)
Query Neighborhood Hits	438	Target Neighborhood Hits	350	Shared Neighborhood Hits	184
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	0.00298849 (rank : 58)	NC score	0.391987 (rank : 26)
Query Neighborhood Hits	438	Target Neighborhood Hits	266	Shared Neighborhood Hits	163
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

DNMBP_HUMAN
θ value	0.00298849 (rank : 59)	NC score	0.360709 (rank : 45)
Query Neighborhood Hits	438	Target Neighborhood Hits	413	Shared Neighborhood Hits	176
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SH3G1_MOUSE
θ value	0.00298849 (rank : 60)	NC score	0.381752 (rank : 31)
Query Neighborhood Hits	438	Target Neighborhood Hits	291	Shared Neighborhood Hits	160
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

ARHG9_HUMAN
θ value	0.00390308 (rank : 61)	NC score	0.269736 (rank : 88)
Query Neighborhood Hits	438	Target Neighborhood Hits	235	Shared Neighborhood Hits	144
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

GRAP_HUMAN
θ value	0.00390308 (rank : 62)	NC score	0.360738 (rank : 44)
Query Neighborhood Hits	438	Target Neighborhood Hits	307	Shared Neighborhood Hits	178
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

NCK2_HUMAN
θ value	0.00390308 (rank : 63)	NC score	0.368834 (rank : 37)
Query Neighborhood Hits	438	Target Neighborhood Hits	310	Shared Neighborhood Hits	172
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

RUSC1_HUMAN
θ value	0.00390308 (rank : 64)	NC score	0.305968 (rank : 76)
Query Neighborhood Hits	438	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SPTA1_HUMAN
θ value	0.00390308 (rank : 65)	NC score	0.168518 (rank : 137)
Query Neighborhood Hits	438	Target Neighborhood Hits	748	Shared Neighborhood Hits	162
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CRKL_HUMAN
θ value	0.00509761 (rank : 66)	NC score	0.345675 (rank : 53)
Query Neighborhood Hits	438	Target Neighborhood Hits	313	Shared Neighborhood Hits	169
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

GRAP_MOUSE
θ value	0.00509761 (rank : 67)	NC score	0.367445 (rank : 40)
Query Neighborhood Hits	438	Target Neighborhood Hits	309	Shared Neighborhood Hits	174
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

VINEX_MOUSE
θ value	0.00509761 (rank : 68)	NC score	0.404914 (rank : 21)
Query Neighborhood Hits	438	Target Neighborhood Hits	286	Shared Neighborhood Hits	169
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

AHI1_MOUSE
θ value	0.00665767 (rank : 69)	NC score	0.287388 (rank : 82)
Query Neighborhood Hits	438	Target Neighborhood Hits	496	Shared Neighborhood Hits	166
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

DNMBP_MOUSE
θ value	0.00665767 (rank : 70)	NC score	0.350355 (rank : 50)
Query Neighborhood Hits	438	Target Neighborhood Hits	435	Shared Neighborhood Hits	188
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

EPS8_MOUSE
θ value	0.00665767 (rank : 71)	NC score	0.203863 (rank : 117)
Query Neighborhood Hits	438	Target Neighborhood Hits	157	Shared Neighborhood Hits	113
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

GAK6_HUMAN
θ value	0.00665767 (rank : 72)	NC score	0.136328 (rank : 165)
Query Neighborhood Hits	438	Target Neighborhood Hits	392	Shared Neighborhood Hits	119
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NPHP1_MOUSE
θ value	0.00665767 (rank : 73)	NC score	0.330167 (rank : 61)
Query Neighborhood Hits	438	Target Neighborhood Hits	267	Shared Neighborhood Hits	150
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

TRI66_HUMAN
θ value	0.00665767 (rank : 74)	NC score	0.073631 (rank : 362)
Query Neighborhood Hits	438	Target Neighborhood Hits	479	Shared Neighborhood Hits	71
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ARHG9_MOUSE
θ value	0.00869519 (rank : 75)	NC score	0.267334 (rank : 89)
Query Neighborhood Hits	438	Target Neighborhood Hits	234	Shared Neighborhood Hits	144
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

DDEF2_HUMAN
θ value	0.00869519 (rank : 76)	NC score	0.183006 (rank : 132)
Query Neighborhood Hits	438	Target Neighborhood Hits	599	Shared Neighborhood Hits	168
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.00869519 (rank : 77)	NC score	0.188964 (rank : 126)
Query Neighborhood Hits	438	Target Neighborhood Hits	625	Shared Neighborhood Hits	169
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

M3K10_HUMAN
θ value	0.00869519 (rank : 78)	NC score	0.103473 (rank : 231)
Query Neighborhood Hits	438	Target Neighborhood Hits	1071	Shared Neighborhood Hits	161
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MLL3_HUMAN
θ value	0.00869519 (rank : 79)	NC score	0.136221 (rank : 166)
Query Neighborhood Hits	438	Target Neighborhood Hits	1644	Shared Neighborhood Hits	210
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PO6F2_MOUSE
θ value	0.00869519 (rank : 80)	NC score	0.069217 (rank : 389)
Query Neighborhood Hits	438	Target Neighborhood Hits	639	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

DOK1_HUMAN
θ value	0.0113563 (rank : 81)	NC score	0.072159 (rank : 368)
Query Neighborhood Hits	438	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

EPS8_HUMAN
θ value	0.0113563 (rank : 82)	NC score	0.197529 (rank : 122)
Query Neighborhood Hits	438	Target Neighborhood Hits	151	Shared Neighborhood Hits	105
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

OSTF1_MOUSE
θ value	0.0113563 (rank : 83)	NC score	0.304737 (rank : 78)
Query Neighborhood Hits	438	Target Neighborhood Hits	467	Shared Neighborhood Hits	170
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

VINEX_HUMAN
θ value	0.0113563 (rank : 84)	NC score	0.398711 (rank : 24)
Query Neighborhood Hits	438	Target Neighborhood Hits	270	Shared Neighborhood Hits	163
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

CRKL_MOUSE
θ value	0.0148317 (rank : 85)	NC score	0.325136 (rank : 66)
Query Neighborhood Hits	438	Target Neighborhood Hits	307	Shared Neighborhood Hits	163
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

MLL3_MOUSE
θ value	0.0148317 (rank : 86)	NC score	0.122254 (rank : 194)
Query Neighborhood Hits	438	Target Neighborhood Hits	1399	Shared Neighborhood Hits	185
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

OSTF1_HUMAN
θ value	0.0148317 (rank : 87)	NC score	0.305856 (rank : 77)
Query Neighborhood Hits	438	Target Neighborhood Hits	466	Shared Neighborhood Hits	169
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ARI1A_HUMAN
θ value	0.0193708 (rank : 88)	NC score	0.129189 (rank : 183)
Query Neighborhood Hits	438	Target Neighborhood Hits	787	Shared Neighborhood Hits	149
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CD2L7_HUMAN
θ value	0.0193708 (rank : 89)	NC score	0.034769 (rank : 609)
Query Neighborhood Hits	438	Target Neighborhood Hits	1275	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

FA47B_HUMAN
θ value	0.0193708 (rank : 90)	NC score	0.124255 (rank : 192)
Query Neighborhood Hits	438	Target Neighborhood Hits	431	Shared Neighborhood Hits	126
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GAK10_HUMAN
θ value	0.0193708 (rank : 91)	NC score	0.128091 (rank : 186)
Query Neighborhood Hits	438	Target Neighborhood Hits	289	Shared Neighborhood Hits	98
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MUC1_HUMAN
θ value	0.0193708 (rank : 92)	NC score	0.134190 (rank : 170)
Query Neighborhood Hits	438	Target Neighborhood Hits	975	Shared Neighborhood Hits	176
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NPHP1_HUMAN
θ value	0.0193708 (rank : 93)	NC score	0.300611 (rank : 79)
Query Neighborhood Hits	438	Target Neighborhood Hits	288	Shared Neighborhood Hits	140
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

GAK12_HUMAN
θ value	0.0252991 (rank : 94)	NC score	0.133761 (rank : 172)
Query Neighborhood Hits	438	Target Neighborhood Hits	374	Shared Neighborhood Hits	113
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MGR1_MOUSE
θ value	0.0252991 (rank : 95)	NC score	0.041177 (rank : 585)
Query Neighborhood Hits	438	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

SH3G3_HUMAN
θ value	0.0252991 (rank : 96)	NC score	0.377026 (rank : 33)
Query Neighborhood Hits	438	Target Neighborhood Hits	222	Shared Neighborhood Hits	153
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SRBS1_MOUSE
θ value	0.0252991 (rank : 97)	NC score	0.375925 (rank : 35)
Query Neighborhood Hits	438	Target Neighborhood Hits	409	Shared Neighborhood Hits	183
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

MYST3_HUMAN
θ value	0.0330416 (rank : 98)	NC score	0.076553 (rank : 348)
Query Neighborhood Hits	438	Target Neighborhood Hits	772	Shared Neighborhood Hits	84
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	0.0330416 (rank : 99)	NC score	0.074601 (rank : 359)
Query Neighborhood Hits	438	Target Neighborhood Hits	688	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NOTC2_HUMAN
θ value	0.0330416 (rank : 100)	NC score	0.021853 (rank : 640)
Query Neighborhood Hits	438	Target Neighborhood Hits	1113	Shared Neighborhood Hits	111
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RGS3_HUMAN
θ value	0.0330416 (rank : 101)	NC score	0.110159 (rank : 218)
Query Neighborhood Hits	438	Target Neighborhood Hits	1375	Shared Neighborhood Hits	200
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ABI1_MOUSE
θ value	0.0431538 (rank : 102)	NC score	0.359118 (rank : 46)
Query Neighborhood Hits	438	Target Neighborhood Hits	246	Shared Neighborhood Hits	162
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

RHG04_HUMAN
θ value	0.0431538 (rank : 103)	NC score	0.238912 (rank : 106)
Query Neighborhood Hits	438	Target Neighborhood Hits	307	Shared Neighborhood Hits	155
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RUSC1_MOUSE
θ value	0.0431538 (rank : 104)	NC score	0.271994 (rank : 87)
Query Neighborhood Hits	438	Target Neighborhood Hits	206	Shared Neighborhood Hits	128
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SFPQ_MOUSE
θ value	0.0431538 (rank : 105)	NC score	0.109833 (rank : 220)
Query Neighborhood Hits	438	Target Neighborhood Hits	958	Shared Neighborhood Hits	122
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CRK_MOUSE
θ value	0.0563607 (rank : 106)	NC score	0.329808 (rank : 62)
Query Neighborhood Hits	438	Target Neighborhood Hits	314	Shared Neighborhood Hits	173
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

NCF1_HUMAN
θ value	0.0563607 (rank : 107)	NC score	0.379250 (rank : 32)
Query Neighborhood Hits	438	Target Neighborhood Hits	198	Shared Neighborhood Hits	144
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

PACN2_HUMAN
θ value	0.0563607 (rank : 108)	NC score	0.338247 (rank : 57)
Query Neighborhood Hits	438	Target Neighborhood Hits	339	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PHC2_HUMAN
θ value	0.0563607 (rank : 109)	NC score	0.103373 (rank : 234)
Query Neighborhood Hits	438	Target Neighborhood Hits	388	Shared Neighborhood Hits	118
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

RAPH1_HUMAN
θ value	0.0563607 (rank : 110)	NC score	0.139300 (rank : 157)
Query Neighborhood Hits	438	Target Neighborhood Hits	593	Shared Neighborhood Hits	131
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

ABI1_HUMAN
θ value	0.0736092 (rank : 111)	NC score	0.346882 (rank : 51)
Query Neighborhood Hits	438	Target Neighborhood Hits	257	Shared Neighborhood Hits	168
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ARHG6_HUMAN
θ value	0.0736092 (rank : 112)	NC score	0.319672 (rank : 68)
Query Neighborhood Hits	438	Target Neighborhood Hits	376	Shared Neighborhood Hits	160
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	0.0736092 (rank : 113)	NC score	0.325989 (rank : 65)
Query Neighborhood Hits	438	Target Neighborhood Hits	394	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ES8L2_HUMAN
θ value	0.0736092 (rank : 114)	NC score	0.204093 (rank : 116)
Query Neighborhood Hits	438	Target Neighborhood Hits	193	Shared Neighborhood Hits	132
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

HCK_HUMAN
θ value	0.0736092 (rank : 115)	NC score	0.097872 (rank : 252)
Query Neighborhood Hits	438	Target Neighborhood Hits	1035	Shared Neighborhood Hits	165
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

NCF1_MOUSE
θ value	0.0736092 (rank : 116)	NC score	0.367341 (rank : 41)
Query Neighborhood Hits	438	Target Neighborhood Hits	198	Shared Neighborhood Hits	149
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

PTN23_MOUSE
θ value	0.0736092 (rank : 117)	NC score	0.065922 (rank : 415)
Query Neighborhood Hits	438	Target Neighborhood Hits	726	Shared Neighborhood Hits	122
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SOX13_MOUSE
θ value	0.0736092 (rank : 118)	NC score	0.072525 (rank : 367)
Query Neighborhood Hits	438	Target Neighborhood Hits	495	Shared Neighborhood Hits	108
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SRBS1_HUMAN
θ value	0.0736092 (rank : 119)	NC score	0.368247 (rank : 38)
Query Neighborhood Hits	438	Target Neighborhood Hits	396	Shared Neighborhood Hits	176
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAM1_HUMAN
θ value	0.0736092 (rank : 120)	NC score	0.341245 (rank : 54)
Query Neighborhood Hits	438	Target Neighborhood Hits	271	Shared Neighborhood Hits	174
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	0.0736092 (rank : 121)	NC score	0.341240 (rank : 55)
Query Neighborhood Hits	438	Target Neighborhood Hits	273	Shared Neighborhood Hits	178
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CCNK_MOUSE
θ value	0.0961366 (rank : 122)	NC score	0.105289 (rank : 224)
Query Neighborhood Hits	438	Target Neighborhood Hits	350	Shared Neighborhood Hits	85
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CSKI1_HUMAN
θ value	0.0961366 (rank : 123)	NC score	0.090141 (rank : 285)
Query Neighborhood Hits	438	Target Neighborhood Hits	997	Shared Neighborhood Hits	167
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	0.0961366 (rank : 124)	NC score	0.090501 (rank : 282)
Query Neighborhood Hits	438	Target Neighborhood Hits	1031	Shared Neighborhood Hits	193
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NCF4_MOUSE
θ value	0.0961366 (rank : 125)	NC score	0.357361 (rank : 47)
Query Neighborhood Hits	438	Target Neighborhood Hits	177	Shared Neighborhood Hits	135
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NEBL_HUMAN
θ value	0.0961366 (rank : 126)	NC score	0.264514 (rank : 90)
Query Neighborhood Hits	438	Target Neighborhood Hits	457	Shared Neighborhood Hits	147
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NOXO1_MOUSE
θ value	0.0961366 (rank : 127)	NC score	0.277479 (rank : 85)
Query Neighborhood Hits	438	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

PACN2_MOUSE
θ value	0.0961366 (rank : 128)	NC score	0.334867 (rank : 58)
Query Neighborhood Hits	438	Target Neighborhood Hits	382	Shared Neighborhood Hits	168
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	0.0961366 (rank : 129)	NC score	0.316780 (rank : 70)
Query Neighborhood Hits	438	Target Neighborhood Hits	385	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	0.0961366 (rank : 130)	NC score	0.320160 (rank : 67)
Query Neighborhood Hits	438	Target Neighborhood Hits	380	Shared Neighborhood Hits	153
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

RERE_HUMAN
θ value	0.0961366 (rank : 131)	NC score	0.139382 (rank : 156)
Query Neighborhood Hits	438	Target Neighborhood Hits	779	Shared Neighborhood Hits	129
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	0.0961366 (rank : 132)	NC score	0.146920 (rank : 152)
Query Neighborhood Hits	438	Target Neighborhood Hits	785	Shared Neighborhood Hits	130
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RNC_HUMAN
θ value	0.0961366 (rank : 133)	NC score	0.110223 (rank : 217)
Query Neighborhood Hits	438	Target Neighborhood Hits	176	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

SH3G1_HUMAN
θ value	0.0961366 (rank : 134)	NC score	0.354960 (rank : 49)
Query Neighborhood Hits	438	Target Neighborhood Hits	307	Shared Neighborhood Hits	157
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SON_HUMAN
θ value	0.0961366 (rank : 135)	NC score	0.133682 (rank : 173)
Query Neighborhood Hits	438	Target Neighborhood Hits	1568	Shared Neighborhood Hits	215
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

STAM2_MOUSE
θ value	0.0961366 (rank : 136)	NC score	0.339911 (rank : 56)
Query Neighborhood Hits	438	Target Neighborhood Hits	285	Shared Neighborhood Hits	174
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TTBK1_HUMAN
θ value	0.0961366 (rank : 137)	NC score	0.039109 (rank : 592)
Query Neighborhood Hits	438	Target Neighborhood Hits	1058	Shared Neighborhood Hits	76
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

DDEF1_MOUSE
θ value	0.125558 (rank : 138)	NC score	0.187140 (rank : 127)
Query Neighborhood Hits	438	Target Neighborhood Hits	592	Shared Neighborhood Hits	174
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DLG5_HUMAN
θ value	0.125558 (rank : 139)	NC score	0.054355 (rank : 525)
Query Neighborhood Hits	438	Target Neighborhood Hits	1088	Shared Neighborhood Hits	97
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

EGR2_MOUSE
θ value	0.125558 (rank : 140)	NC score	0.003417 (rank : 670)
Query Neighborhood Hits	438	Target Neighborhood Hits	745	Shared Neighborhood Hits	20
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

SH3G3_MOUSE
θ value	0.125558 (rank : 141)	NC score	0.371292 (rank : 36)
Query Neighborhood Hits	438	Target Neighborhood Hits	236	Shared Neighborhood Hits	157
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

STAC_HUMAN
θ value	0.125558 (rank : 142)	NC score	0.346658 (rank : 52)
Query Neighborhood Hits	438	Target Neighborhood Hits	276	Shared Neighborhood Hits	156
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

GSCR1_HUMAN
θ value	0.163984 (rank : 143)	NC score	0.148217 (rank : 148)
Query Neighborhood Hits	438	Target Neighborhood Hits	674	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

IF4G1_MOUSE
θ value	0.163984 (rank : 144)	NC score	0.065838 (rank : 417)
Query Neighborhood Hits	438	Target Neighborhood Hits	534	Shared Neighborhood Hits	109
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

LYN_HUMAN
θ value	0.163984 (rank : 145)	NC score	0.085885 (rank : 303)
Query Neighborhood Hits	438	Target Neighborhood Hits	1022	Shared Neighborhood Hits	153
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

NCF2_HUMAN
θ value	0.163984 (rank : 146)	NC score	0.407357 (rank : 18)
Query Neighborhood Hits	438	Target Neighborhood Hits	229	Shared Neighborhood Hits	145
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

PACN1_HUMAN
θ value	0.163984 (rank : 147)	NC score	0.328708 (rank : 63)
Query Neighborhood Hits	438	Target Neighborhood Hits	320	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	0.163984 (rank : 148)	NC score	0.330720 (rank : 59)
Query Neighborhood Hits	438	Target Neighborhood Hits	283	Shared Neighborhood Hits	158
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

RUSC2_HUMAN
θ value	0.163984 (rank : 149)	NC score	0.155121 (rank : 145)
Query Neighborhood Hits	438	Target Neighborhood Hits	205	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SOX13_HUMAN
θ value	0.163984 (rank : 150)	NC score	0.081368 (rank : 319)
Query Neighborhood Hits	438	Target Neighborhood Hits	464	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SPT5H_HUMAN
θ value	0.163984 (rank : 151)	NC score	0.136392 (rank : 164)
Query Neighborhood Hits	438	Target Neighborhood Hits	436	Shared Neighborhood Hits	110
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.163984 (rank : 152)	NC score	0.135767 (rank : 168)
Query Neighborhood Hits	438	Target Neighborhood Hits	437	Shared Neighborhood Hits	109
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPTA1_MOUSE
θ value	0.163984 (rank : 153)	NC score	0.158674 (rank : 142)
Query Neighborhood Hits	438	Target Neighborhood Hits	675	Shared Neighborhood Hits	152
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SRGP2_MOUSE
θ value	0.163984 (rank : 154)	NC score	0.189327 (rank : 125)
Query Neighborhood Hits	438	Target Neighborhood Hits	324	Shared Neighborhood Hits	145
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

WASL_MOUSE
θ value	0.163984 (rank : 155)	NC score	0.130231 (rank : 181)
Query Neighborhood Hits	438	Target Neighborhood Hits	339	Shared Neighborhood Hits	78
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ACK1_MOUSE
θ value	0.21417 (rank : 156)	NC score	0.055026 (rank : 511)
Query Neighborhood Hits	438	Target Neighborhood Hits	1080	Shared Neighborhood Hits	153
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ENAM_MOUSE
θ value	0.21417 (rank : 157)	NC score	0.076225 (rank : 350)
Query Neighborhood Hits	438	Target Neighborhood Hits	229	Shared Neighborhood Hits	58
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

GAK7_HUMAN
θ value	0.21417 (rank : 158)	NC score	0.112044 (rank : 210)
Query Neighborhood Hits	438	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

LYN_MOUSE
θ value	0.21417 (rank : 159)	NC score	0.085127 (rank : 305)
Query Neighborhood Hits	438	Target Neighborhood Hits	1023	Shared Neighborhood Hits	154
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MCF2L_MOUSE
θ value	0.21417 (rank : 160)	NC score	0.126546 (rank : 189)
Query Neighborhood Hits	438	Target Neighborhood Hits	255	Shared Neighborhood Hits	52
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

PLS1_MOUSE
θ value	0.21417 (rank : 161)	NC score	0.039006 (rank : 594)
Query Neighborhood Hits	438	Target Neighborhood Hits	58	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJ00, O54730, O54731, Q9D1F8	Gene names	Plscr1, Tra1b, Tras1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Transplantability-associated protein 1) (TRA1) (NOR1).

PRRT3_HUMAN
θ value	0.21417 (rank : 162)	NC score	0.148079 (rank : 149)
Query Neighborhood Hits	438	Target Neighborhood Hits	998	Shared Neighborhood Hits	192
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RHG26_HUMAN
θ value	0.21417 (rank : 163)	NC score	0.185702 (rank : 128)
Query Neighborhood Hits	438	Target Neighborhood Hits	281	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SF04_HUMAN
θ value	0.21417 (rank : 164)	NC score	0.041807 (rank : 582)
Query Neighborhood Hits	438	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

SPEG_MOUSE
θ value	0.21417 (rank : 165)	NC score	0.038593 (rank : 599)
Query Neighborhood Hits	438	Target Neighborhood Hits	1959	Shared Neighborhood Hits	189
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TAB3_MOUSE
θ value	0.21417 (rank : 166)	NC score	0.090452 (rank : 283)
Query Neighborhood Hits	438	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

WASL_HUMAN
θ value	0.21417 (rank : 167)	NC score	0.126758 (rank : 188)
Query Neighborhood Hits	438	Target Neighborhood Hits	312	Shared Neighborhood Hits	78
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

FGD1_HUMAN
θ value	0.279714 (rank : 168)	NC score	0.080449 (rank : 325)
Query Neighborhood Hits	438	Target Neighborhood Hits	367	Shared Neighborhood Hits	77
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

LDB3_MOUSE
θ value	0.279714 (rank : 169)	NC score	0.057663 (rank : 480)
Query Neighborhood Hits	438	Target Neighborhood Hits	510	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

SC24D_HUMAN
θ value	0.279714 (rank : 170)	NC score	0.077420 (rank : 344)
Query Neighborhood Hits	438	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SFPQ_HUMAN
θ value	0.279714 (rank : 171)	NC score	0.102949 (rank : 235)
Query Neighborhood Hits	438	Target Neighborhood Hits	986	Shared Neighborhood Hits	117
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

VAV3_HUMAN
θ value	0.279714 (rank : 172)	NC score	0.249350 (rank : 102)
Query Neighborhood Hits	438	Target Neighborhood Hits	398	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

WASF1_MOUSE
θ value	0.279714 (rank : 173)	NC score	0.100502 (rank : 245)
Query Neighborhood Hits	438	Target Neighborhood Hits	261	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

ZYX_HUMAN
θ value	0.279714 (rank : 174)	NC score	0.056938 (rank : 492)
Query Neighborhood Hits	438	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

BLK_HUMAN
θ value	0.365318 (rank : 175)	NC score	0.080985 (rank : 323)
Query Neighborhood Hits	438	Target Neighborhood Hits	994	Shared Neighborhood Hits	138
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

EP300_HUMAN
θ value	0.365318 (rank : 176)	NC score	0.104880 (rank : 225)
Query Neighborhood Hits	438	Target Neighborhood Hits	821	Shared Neighborhood Hits	156
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ES8L2_MOUSE
θ value	0.365318 (rank : 177)	NC score	0.190894 (rank : 123)
Query Neighborhood Hits	438	Target Neighborhood Hits	169	Shared Neighborhood Hits	119
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

FOXJ2_HUMAN
θ value	0.365318 (rank : 178)	NC score	0.023256 (rank : 635)
Query Neighborhood Hits	438	Target Neighborhood Hits	239	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

MACF1_MOUSE
θ value	0.365318 (rank : 179)	NC score	0.024923 (rank : 629)
Query Neighborhood Hits	438	Target Neighborhood Hits	1313	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MBD6_HUMAN
θ value	0.365318 (rank : 180)	NC score	0.133320 (rank : 174)
Query Neighborhood Hits	438	Target Neighborhood Hits	349	Shared Neighborhood Hits	71
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MK07_MOUSE
θ value	0.365318 (rank : 181)	NC score	0.024738 (rank : 630)
Query Neighborhood Hits	438	Target Neighborhood Hits	1054	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

NEBU_HUMAN
θ value	0.365318 (rank : 182)	NC score	0.230376 (rank : 108)
Query Neighborhood Hits	438	Target Neighborhood Hits	420	Shared Neighborhood Hits	150
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

OGFR_HUMAN
θ value	0.365318 (rank : 183)	NC score	0.135229 (rank : 169)
Query Neighborhood Hits	438	Target Neighborhood Hits	1582	Shared Neighborhood Hits	221
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

S23IP_MOUSE
θ value	0.365318 (rank : 184)	NC score	0.094175 (rank : 267)
Query Neighborhood Hits	438	Target Neighborhood Hits	363	Shared Neighborhood Hits	103
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SNX18_MOUSE
θ value	0.365318 (rank : 185)	NC score	0.248389 (rank : 104)
Query Neighborhood Hits	438	Target Neighborhood Hits	198	Shared Neighborhood Hits	121
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SRGP2_HUMAN
θ value	0.365318 (rank : 186)	NC score	0.183635 (rank : 131)
Query Neighborhood Hits	438	Target Neighborhood Hits	331	Shared Neighborhood Hits	143
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

STAC_MOUSE
θ value	0.365318 (rank : 187)	NC score	0.330587 (rank : 60)
Query Neighborhood Hits	438	Target Neighborhood Hits	268	Shared Neighborhood Hits	153
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VAV2_HUMAN
θ value	0.365318 (rank : 188)	NC score	0.259754 (rank : 95)
Query Neighborhood Hits	438	Target Neighborhood Hits	453	Shared Neighborhood Hits	167
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	0.365318 (rank : 189)	NC score	0.259679 (rank : 96)
Query Neighborhood Hits	438	Target Neighborhood Hits	456	Shared Neighborhood Hits	169
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

WASF1_HUMAN
θ value	0.365318 (rank : 190)	NC score	0.095618 (rank : 262)
Query Neighborhood Hits	438	Target Neighborhood Hits	260	Shared Neighborhood Hits	73
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

ARHG4_HUMAN
θ value	0.47712 (rank : 191)	NC score	0.250544 (rank : 100)
Query Neighborhood Hits	438	Target Neighborhood Hits	242	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

EGR1_HUMAN
θ value	0.47712 (rank : 192)	NC score	-0.000887 (rank : 675)
Query Neighborhood Hits	438	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

HCK_MOUSE
θ value	0.47712 (rank : 193)	NC score	0.093145 (rank : 272)
Query Neighborhood Hits	438	Target Neighborhood Hits	1029	Shared Neighborhood Hits	162
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HRX_HUMAN
θ value	0.47712 (rank : 194)	NC score	0.062540 (rank : 444)
Query Neighborhood Hits	438	Target Neighborhood Hits	825	Shared Neighborhood Hits	72
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

LOXL1_MOUSE
θ value	0.47712 (rank : 195)	NC score	0.041267 (rank : 584)
Query Neighborhood Hits	438	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

MAGE1_HUMAN
θ value	0.47712 (rank : 196)	NC score	0.103414 (rank : 233)
Query Neighborhood Hits	438	Target Neighborhood Hits	1389	Shared Neighborhood Hits	201
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MKL1_MOUSE
θ value	0.47712 (rank : 197)	NC score	0.092427 (rank : 276)
Query Neighborhood Hits	438	Target Neighborhood Hits	667	Shared Neighborhood Hits	133
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MLL2_HUMAN
θ value	0.47712 (rank : 198)	NC score	0.117879 (rank : 201)
Query Neighborhood Hits	438	Target Neighborhood Hits	1788	Shared Neighborhood Hits	188
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC7_HUMAN
θ value	0.47712 (rank : 199)	NC score	0.115490 (rank : 204)
Query Neighborhood Hits	438	Target Neighborhood Hits	538	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PCD15_MOUSE
θ value	0.47712 (rank : 200)	NC score	0.013799 (rank : 658)
Query Neighborhood Hits	438	Target Neighborhood Hits	262	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCLO_MOUSE
θ value	0.47712 (rank : 201)	NC score	0.110501 (rank : 216)
Query Neighborhood Hits	438	Target Neighborhood Hits	2275	Shared Neighborhood Hits	244
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

STAM2_HUMAN
θ value	0.47712 (rank : 202)	NC score	0.315923 (rank : 71)
Query Neighborhood Hits	438	Target Neighborhood Hits	288	Shared Neighborhood Hits	174
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

SYN1_HUMAN
θ value	0.47712 (rank : 203)	NC score	0.102487 (rank : 239)
Query Neighborhood Hits	438	Target Neighborhood Hits	419	Shared Neighborhood Hits	95
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TITIN_HUMAN
θ value	0.47712 (rank : 204)	NC score	0.029942 (rank : 618)
Query Neighborhood Hits	438	Target Neighborhood Hits	2923	Shared Neighborhood Hits	155
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TPO_MOUSE
θ value	0.47712 (rank : 205)	NC score	0.074923 (rank : 357)
Query Neighborhood Hits	438	Target Neighborhood Hits	258	Shared Neighborhood Hits	74
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

VAV3_MOUSE
θ value	0.47712 (rank : 206)	NC score	0.242992 (rank : 105)
Query Neighborhood Hits	438	Target Neighborhood Hits	404	Shared Neighborhood Hits	166
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

YLPM1_HUMAN
θ value	0.47712 (rank : 207)	NC score	0.116050 (rank : 203)
Query Neighborhood Hits	438	Target Neighborhood Hits	670	Shared Neighborhood Hits	130
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ANX11_MOUSE
θ value	0.62314 (rank : 208)	NC score	0.032423 (rank : 613)
Query Neighborhood Hits	438	Target Neighborhood Hits	200	Shared Neighborhood Hits	51
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

BAT2_HUMAN
θ value	0.62314 (rank : 209)	NC score	0.131333 (rank : 177)
Query Neighborhood Hits	438	Target Neighborhood Hits	931	Shared Neighborhood Hits	163
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EPN1_HUMAN
θ value	0.62314 (rank : 210)	NC score	0.060183 (rank : 460)
Query Neighborhood Hits	438	Target Neighborhood Hits	206	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

FGR_HUMAN
θ value	0.62314 (rank : 211)	NC score	0.102323 (rank : 241)
Query Neighborhood Hits	438	Target Neighborhood Hits	1067	Shared Neighborhood Hits	166
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

GNDS_HUMAN
θ value	0.62314 (rank : 212)	NC score	0.032975 (rank : 612)
Query Neighborhood Hits	438	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

MNT_MOUSE
θ value	0.62314 (rank : 213)	NC score	0.086731 (rank : 299)
Query Neighborhood Hits	438	Target Neighborhood Hits	432	Shared Neighborhood Hits	81
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NCF4_HUMAN
θ value	0.62314 (rank : 214)	NC score	0.327024 (rank : 64)
Query Neighborhood Hits	438	Target Neighborhood Hits	161	Shared Neighborhood Hits	122
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

RIMB1_MOUSE
θ value	0.62314 (rank : 215)	NC score	0.131157 (rank : 178)
Query Neighborhood Hits	438	Target Neighborhood Hits	1376	Shared Neighborhood Hits	192
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_HUMAN
θ value	0.62314 (rank : 216)	NC score	0.224687 (rank : 110)
Query Neighborhood Hits	438	Target Neighborhood Hits	263	Shared Neighborhood Hits	116
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SNX18_HUMAN
θ value	0.62314 (rank : 217)	NC score	0.237632 (rank : 107)
Query Neighborhood Hits	438	Target Neighborhood Hits	207	Shared Neighborhood Hits	125
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SYN1_MOUSE
θ value	0.62314 (rank : 218)	NC score	0.095533 (rank : 263)
Query Neighborhood Hits	438	Target Neighborhood Hits	363	Shared Neighborhood Hits	84
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

WDR33_HUMAN
θ value	0.62314 (rank : 219)	NC score	0.038637 (rank : 598)
Query Neighborhood Hits	438	Target Neighborhood Hits	638	Shared Neighborhood Hits	71
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

BRD4_HUMAN
θ value	0.813845 (rank : 220)	NC score	0.093307 (rank : 271)
Query Neighborhood Hits	438	Target Neighborhood Hits	851	Shared Neighborhood Hits	124
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DYN1_MOUSE
θ value	0.813845 (rank : 221)	NC score	0.024241 (rank : 632)
Query Neighborhood Hits	438	Target Neighborhood Hits	168	Shared Neighborhood Hits	31
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

MUC5B_HUMAN
θ value	0.813845 (rank : 222)	NC score	0.052315 (rank : 553)
Query Neighborhood Hits	438	Target Neighborhood Hits	1020	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYBPH_HUMAN
θ value	0.813845 (rank : 223)	NC score	0.025454 (rank : 627)
Query Neighborhood Hits	438	Target Neighborhood Hits	256	Shared Neighborhood Hits	13
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

RIMB1_HUMAN
θ value	0.813845 (rank : 224)	NC score	0.147735 (rank : 151)
Query Neighborhood Hits	438	Target Neighborhood Hits	1479	Shared Neighborhood Hits	187
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RPB1_HUMAN
θ value	0.813845 (rank : 225)	NC score	0.068575 (rank : 394)
Query Neighborhood Hits	438	Target Neighborhood Hits	362	Shared Neighborhood Hits	64
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.813845 (rank : 226)	NC score	0.068855 (rank : 392)
Query Neighborhood Hits	438	Target Neighborhood Hits	363	Shared Neighborhood Hits	64
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SC24B_HUMAN
θ value	0.813845 (rank : 227)	NC score	0.038545 (rank : 600)
Query Neighborhood Hits	438	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

SRC_HUMAN
θ value	0.813845 (rank : 228)	NC score	0.102766 (rank : 238)
Query Neighborhood Hits	438	Target Neighborhood Hits	1058	Shared Neighborhood Hits	174
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SYNPO_MOUSE
θ value	0.813845 (rank : 229)	NC score	0.068818 (rank : 393)
Query Neighborhood Hits	438	Target Neighborhood Hits	242	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

WASIP_HUMAN
θ value	0.813845 (rank : 230)	NC score	0.157752 (rank : 143)
Query Neighborhood Hits	438	Target Neighborhood Hits	458	Shared Neighborhood Hits	102
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

YES_HUMAN
θ value	0.813845 (rank : 231)	NC score	0.102917 (rank : 236)
Query Neighborhood Hits	438	Target Neighborhood Hits	1059	Shared Neighborhood Hits	167
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	0.813845 (rank : 232)	NC score	0.103429 (rank : 232)
Query Neighborhood Hits	438	Target Neighborhood Hits	1052	Shared Neighborhood Hits	166
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZN687_HUMAN
θ value	0.813845 (rank : 233)	NC score	0.024356 (rank : 631)
Query Neighborhood Hits	438	Target Neighborhood Hits	1244	Shared Neighborhood Hits	125
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AAK1_HUMAN
θ value	1.06291 (rank : 234)	NC score	0.041646 (rank : 583)
Query Neighborhood Hits	438	Target Neighborhood Hits	1077	Shared Neighborhood Hits	130
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BTK_HUMAN
θ value	1.06291 (rank : 235)	NC score	0.097566 (rank : 254)
Query Neighborhood Hits	438	Target Neighborhood Hits	1026	Shared Neighborhood Hits	167
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

CD248_HUMAN
θ value	1.06291 (rank : 236)	NC score	0.052741 (rank : 547)
Query Neighborhood Hits	438	Target Neighborhood Hits	679	Shared Neighborhood Hits	128
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

DYN1_HUMAN
θ value	1.06291 (rank : 237)	NC score	0.028707 (rank : 620)
Query Neighborhood Hits	438	Target Neighborhood Hits	216	Shared Neighborhood Hits	38
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

FRK_HUMAN
θ value	1.06291 (rank : 238)	NC score	0.087021 (rank : 298)
Query Neighborhood Hits	438	Target Neighborhood Hits	1058	Shared Neighborhood Hits	169
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

GAK8_HUMAN
θ value	1.06291 (rank : 239)	NC score	0.109420 (rank : 221)
Query Neighborhood Hits	438	Target Neighborhood Hits	145	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

K1688_MOUSE
θ value	1.06291 (rank : 240)	NC score	0.075684 (rank : 354)
Query Neighborhood Hits	438	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

NFRKB_MOUSE
θ value	1.06291 (rank : 241)	NC score	0.066192 (rank : 411)
Query Neighborhood Hits	438	Target Neighborhood Hits	393	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NOXO1_HUMAN
θ value	1.06291 (rank : 242)	NC score	0.210448 (rank : 114)
Query Neighborhood Hits	438	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

PLCG2_HUMAN
θ value	1.06291 (rank : 243)	NC score	0.203401 (rank : 118)
Query Neighborhood Hits	438	Target Neighborhood Hits	280	Shared Neighborhood Hits	143
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PRP1_HUMAN
θ value	1.06291 (rank : 244)	NC score	0.132054 (rank : 176)
Query Neighborhood Hits	438	Target Neighborhood Hits	385	Shared Neighborhood Hits	84
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PTK6_HUMAN
θ value	1.06291 (rank : 245)	NC score	0.077532 (rank : 343)
Query Neighborhood Hits	438	Target Neighborhood Hits	1020	Shared Neighborhood Hits	154
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

RIMB2_MOUSE
θ value	1.06291 (rank : 246)	NC score	0.215348 (rank : 112)
Query Neighborhood Hits	438	Target Neighborhood Hits	246	Shared Neighborhood Hits	103
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RUSC2_MOUSE
θ value	1.06291 (rank : 247)	NC score	0.140670 (rank : 155)
Query Neighborhood Hits	438	Target Neighborhood Hits	305	Shared Neighborhood Hits	103
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SELO_HUMAN
θ value	1.06291 (rank : 248)	NC score	0.024950 (rank : 628)
Query Neighborhood Hits	438	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BVL4, Q8WUI0	Gene names	SELO
Domain Architecture
Description	Selenoprotein O.

SIN3A_MOUSE
θ value	1.06291 (rank : 249)	NC score	0.040378 (rank : 586)
Query Neighborhood Hits	438	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SYP2L_MOUSE
θ value	1.06291 (rank : 250)	NC score	0.055877 (rank : 504)
Query Neighborhood Hits	438	Target Neighborhood Hits	289	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TXND2_HUMAN
θ value	1.06291 (rank : 251)	NC score	0.073870 (rank : 361)
Query Neighborhood Hits	438	Target Neighborhood Hits	793	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WASF2_MOUSE
θ value	1.06291 (rank : 252)	NC score	0.110846 (rank : 214)
Query Neighborhood Hits	438	Target Neighborhood Hits	315	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_HUMAN
θ value	1.06291 (rank : 253)	NC score	0.095102 (rank : 266)
Query Neighborhood Hits	438	Target Neighborhood Hits	204	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASIP_MOUSE
θ value	1.06291 (rank : 254)	NC score	0.161292 (rank : 140)
Query Neighborhood Hits	438	Target Neighborhood Hits	392	Shared Neighborhood Hits	102
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ATX2_MOUSE
θ value	1.38821 (rank : 255)	NC score	0.079735 (rank : 329)
Query Neighborhood Hits	438	Target Neighborhood Hits	445	Shared Neighborhood Hits	110
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BCL9_HUMAN
θ value	1.38821 (rank : 256)	NC score	0.119588 (rank : 198)
Query Neighborhood Hits	438	Target Neighborhood Hits	1008	Shared Neighborhood Hits	189
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CJ055_HUMAN
θ value	1.38821 (rank : 257)	NC score	0.041880 (rank : 581)
Query Neighborhood Hits	438	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SWW7, Q8NAK4	Gene names	C10orf55
Domain Architecture	No domain graphic available
Description	Protein C10orf55.

CK056_MOUSE
θ value	1.38821 (rank : 258)	NC score	0.052387 (rank : 551)
Query Neighborhood Hits	438	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U2I3, Q3TWF5, Q6P543, Q80T93, Q811J6, Q8BI34, Q8VE55	Gene names	Kiaa1759
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf56 homolog.

EP400_MOUSE
θ value	1.38821 (rank : 259)	NC score	0.050529 (rank : 570)
Query Neighborhood Hits	438	Target Neighborhood Hits	592	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EPN1_MOUSE
θ value	1.38821 (rank : 260)	NC score	0.057121 (rank : 488)
Query Neighborhood Hits	438	Target Neighborhood Hits	240	Shared Neighborhood Hits	55
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

ESX1L_HUMAN
θ value	1.38821 (rank : 261)	NC score	0.028213 (rank : 622)
Query Neighborhood Hits	438	Target Neighborhood Hits	498	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

FMN1A_MOUSE
θ value	1.38821 (rank : 262)	NC score	0.077169 (rank : 345)
Query Neighborhood Hits	438	Target Neighborhood Hits	423	Shared Neighborhood Hits	75
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	1.38821 (rank : 263)	NC score	0.076142 (rank : 351)
Query Neighborhood Hits	438	Target Neighborhood Hits	447	Shared Neighborhood Hits	77
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FNBP2_HUMAN
θ value	1.38821 (rank : 264)	NC score	0.169189 (rank : 136)
Query Neighborhood Hits	438	Target Neighborhood Hits	432	Shared Neighborhood Hits	156
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FYN_HUMAN
θ value	1.38821 (rank : 265)	NC score	0.101898 (rank : 242)
Query Neighborhood Hits	438	Target Neighborhood Hits	1078	Shared Neighborhood Hits	171
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	1.38821 (rank : 266)	NC score	0.103554 (rank : 230)
Query Neighborhood Hits	438	Target Neighborhood Hits	1073	Shared Neighborhood Hits	171
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

IL2RB_MOUSE
θ value	1.38821 (rank : 267)	NC score	0.026597 (rank : 626)
Query Neighborhood Hits	438	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

MNT_HUMAN
θ value	1.38821 (rank : 268)	NC score	0.100333 (rank : 246)
Query Neighborhood Hits	438	Target Neighborhood Hits	496	Shared Neighborhood Hits	107
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PABP1_HUMAN
θ value	1.38821 (rank : 269)	NC score	0.013980 (rank : 657)
Query Neighborhood Hits	438	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_MOUSE
θ value	1.38821 (rank : 270)	NC score	0.014071 (rank : 656)
Query Neighborhood Hits	438	Target Neighborhood Hits	278	Shared Neighborhood Hits	20
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PDLI7_HUMAN
θ value	1.38821 (rank : 271)	NC score	0.043085 (rank : 578)
Query Neighborhood Hits	438	Target Neighborhood Hits	547	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PRB4S_HUMAN
θ value	1.38821 (rank : 272)	NC score	0.130806 (rank : 180)
Query Neighborhood Hits	438	Target Neighborhood Hits	330	Shared Neighborhood Hits	78
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP2_MOUSE
θ value	1.38821 (rank : 273)	NC score	0.168282 (rank : 138)
Query Neighborhood Hits	438	Target Neighborhood Hits	347	Shared Neighborhood Hits	86
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

R3HD2_MOUSE
θ value	1.38821 (rank : 274)	NC score	0.098515 (rank : 250)
Query Neighborhood Hits	438	Target Neighborhood Hits	397	Shared Neighborhood Hits	107
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

SPN90_HUMAN
θ value	1.38821 (rank : 275)	NC score	0.148970 (rank : 147)
Query Neighborhood Hits	438	Target Neighborhood Hits	157	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPTA3_MOUSE
θ value	1.38821 (rank : 276)	NC score	0.096337 (rank : 258)
Query Neighborhood Hits	438	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

TRI66_MOUSE
θ value	1.38821 (rank : 277)	NC score	0.062872 (rank : 438)
Query Neighborhood Hits	438	Target Neighborhood Hits	491	Shared Neighborhood Hits	80
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ACK1_HUMAN
θ value	1.81305 (rank : 278)	NC score	0.055457 (rank : 510)
Query Neighborhood Hits	438	Target Neighborhood Hits	1140	Shared Neighborhood Hits	162
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ARRD1_MOUSE
θ value	1.81305 (rank : 279)	NC score	0.026681 (rank : 625)
Query Neighborhood Hits	438	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ATX2_HUMAN
θ value	1.81305 (rank : 280)	NC score	0.066608 (rank : 408)
Query Neighborhood Hits	438	Target Neighborhood Hits	375	Shared Neighborhood Hits	75
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

BAT3_HUMAN
θ value	1.81305 (rank : 281)	NC score	0.061017 (rank : 455)
Query Neighborhood Hits	438	Target Neighborhood Hits	490	Shared Neighborhood Hits	92
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

IQEC2_HUMAN
θ value	1.81305 (rank : 282)	NC score	0.039452 (rank : 590)
Query Neighborhood Hits	438	Target Neighborhood Hits	403	Shared Neighborhood Hits	65
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	1.81305 (rank : 283)	NC score	0.042057 (rank : 580)
Query Neighborhood Hits	438	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

K1KB8_MOUSE
θ value	1.81305 (rank : 284)	NC score	0.001332 (rank : 671)
Query Neighborhood Hits	438	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

LDB3_HUMAN
θ value	1.81305 (rank : 285)	NC score	0.054438 (rank : 523)
Query Neighborhood Hits	438	Target Neighborhood Hits	497	Shared Neighborhood Hits	71
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MATK_HUMAN
θ value	1.81305 (rank : 286)	NC score	0.055907 (rank : 503)
Query Neighborhood Hits	438	Target Neighborhood Hits	954	Shared Neighborhood Hits	84
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	1.81305 (rank : 287)	NC score	0.054949 (rank : 514)
Query Neighborhood Hits	438	Target Neighborhood Hits	952	Shared Neighborhood Hits	88
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MUC2_HUMAN
θ value	1.81305 (rank : 288)	NC score	0.076399 (rank : 349)
Query Neighborhood Hits	438	Target Neighborhood Hits	906	Shared Neighborhood Hits	103
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUCDL_HUMAN
θ value	1.81305 (rank : 289)	NC score	0.084405 (rank : 312)
Query Neighborhood Hits	438	Target Neighborhood Hits	777	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PCLO_HUMAN
θ value	1.81305 (rank : 290)	NC score	0.112490 (rank : 209)
Query Neighborhood Hits	438	Target Neighborhood Hits	2046	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

S23IP_HUMAN
θ value	1.81305 (rank : 291)	NC score	0.062807 (rank : 439)
Query Neighborhood Hits	438	Target Neighborhood Hits	134	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

WHRN_MOUSE
θ value	1.81305 (rank : 292)	NC score	0.036629 (rank : 604)
Query Neighborhood Hits	438	Target Neighborhood Hits	412	Shared Neighborhood Hits	65
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

ZYX_MOUSE
θ value	1.81305 (rank : 293)	NC score	0.053691 (rank : 532)
Query Neighborhood Hits	438	Target Neighborhood Hits	347	Shared Neighborhood Hits	59
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

ATBF1_MOUSE
θ value	2.36792 (rank : 294)	NC score	0.021993 (rank : 639)
Query Neighborhood Hits	438	Target Neighborhood Hits	1841	Shared Neighborhood Hits	108
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BSN_MOUSE
θ value	2.36792 (rank : 295)	NC score	0.119634 (rank : 197)
Query Neighborhood Hits	438	Target Neighborhood Hits	2057	Shared Neighborhood Hits	227
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAC1A_MOUSE
θ value	2.36792 (rank : 296)	NC score	0.010723 (rank : 660)
Query Neighborhood Hits	438	Target Neighborhood Hits	267	Shared Neighborhood Hits	31
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

FA38A_HUMAN
θ value	2.36792 (rank : 297)	NC score	0.015402 (rank : 653)
Query Neighborhood Hits	438	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q92508	Gene names	FAM38A, KIAA0233
Domain Architecture	No domain graphic available
Description	Protein FAM38A.

K1802_MOUSE
θ value	2.36792 (rank : 298)	NC score	0.095145 (rank : 265)
Query Neighborhood Hits	438	Target Neighborhood Hits	1596	Shared Neighborhood Hits	196
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MYO15_HUMAN
θ value	2.36792 (rank : 299)	NC score	0.058205 (rank : 477)
Query Neighborhood Hits	438	Target Neighborhood Hits	671	Shared Neighborhood Hits	170
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PLCG1_HUMAN
θ value	2.36792 (rank : 300)	NC score	0.204680 (rank : 115)
Query Neighborhood Hits	438	Target Neighborhood Hits	293	Shared Neighborhood Hits	142
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	2.36792 (rank : 301)	NC score	0.212935 (rank : 113)
Query Neighborhood Hits	438	Target Neighborhood Hits	314	Shared Neighborhood Hits	147
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PO6F2_HUMAN
θ value	2.36792 (rank : 302)	NC score	0.053797 (rank : 530)
Query Neighborhood Hits	438	Target Neighborhood Hits	618	Shared Neighborhood Hits	87
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PTN23_HUMAN
θ value	2.36792 (rank : 303)	NC score	0.052734 (rank : 548)
Query Neighborhood Hits	438	Target Neighborhood Hits	646	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SPN90_MOUSE
θ value	2.36792 (rank : 304)	NC score	0.125843 (rank : 191)
Query Neighborhood Hits	438	Target Neighborhood Hits	157	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SRC_MOUSE
θ value	2.36792 (rank : 305)	NC score	0.089246 (rank : 291)
Query Neighborhood Hits	438	Target Neighborhood Hits	1033	Shared Neighborhood Hits	159
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRGP1_HUMAN
θ value	2.36792 (rank : 306)	NC score	0.174004 (rank : 134)
Query Neighborhood Hits	438	Target Neighborhood Hits	390	Shared Neighborhood Hits	143
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SYNPO_HUMAN
θ value	2.36792 (rank : 307)	NC score	0.053938 (rank : 527)
Query Neighborhood Hits	438	Target Neighborhood Hits	281	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

VAX1_HUMAN
θ value	2.36792 (rank : 308)	NC score	0.007006 (rank : 663)
Query Neighborhood Hits	438	Target Neighborhood Hits	355	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SQQ9, Q6ZSX0	Gene names	VAX1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

ATX2L_MOUSE
θ value	3.0926 (rank : 309)	NC score	0.089332 (rank : 290)
Query Neighborhood Hits	438	Target Neighborhood Hits	401	Shared Neighborhood Hits	93
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

BCL9_MOUSE
θ value	3.0926 (rank : 310)	NC score	0.094014 (rank : 268)
Query Neighborhood Hits	438	Target Neighborhood Hits	770	Shared Neighborhood Hits	152
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BLNK_MOUSE
θ value	3.0926 (rank : 311)	NC score	0.079613 (rank : 330)
Query Neighborhood Hits	438	Target Neighborhood Hits	296	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BRD4_MOUSE
θ value	3.0926 (rank : 312)	NC score	0.090634 (rank : 281)
Query Neighborhood Hits	438	Target Neighborhood Hits	845	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BTK_MOUSE
θ value	3.0926 (rank : 313)	NC score	0.090020 (rank : 286)
Query Neighborhood Hits	438	Target Neighborhood Hits	1017	Shared Neighborhood Hits	159
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CBP_HUMAN
θ value	3.0926 (rank : 314)	NC score	0.097225 (rank : 255)
Query Neighborhood Hits	438	Target Neighborhood Hits	941	Shared Neighborhood Hits	160
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CPSF6_HUMAN
θ value	3.0926 (rank : 315)	NC score	0.113576 (rank : 208)
Query Neighborhood Hits	438	Target Neighborhood Hits	359	Shared Neighborhood Hits	88
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	3.0926 (rank : 316)	NC score	0.114751 (rank : 206)
Query Neighborhood Hits	438	Target Neighborhood Hits	356	Shared Neighborhood Hits	89
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRK_HUMAN
θ value	3.0926 (rank : 317)	NC score	0.308299 (rank : 74)
Query Neighborhood Hits	438	Target Neighborhood Hits	308	Shared Neighborhood Hits	169
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

FGR_MOUSE
θ value	3.0926 (rank : 318)	NC score	0.098314 (rank : 251)
Query Neighborhood Hits	438	Target Neighborhood Hits	1069	Shared Neighborhood Hits	168
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

GAK1_HUMAN
θ value	3.0926 (rank : 319)	NC score	0.115272 (rank : 205)
Query Neighborhood Hits	438	Target Neighborhood Hits	268	Shared Neighborhood Hits	88
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LASP1_HUMAN
θ value	3.0926 (rank : 320)	NC score	0.263020 (rank : 92)
Query Neighborhood Hits	438	Target Neighborhood Hits	293	Shared Neighborhood Hits	146
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	3.0926 (rank : 321)	NC score	0.260295 (rank : 94)
Query Neighborhood Hits	438	Target Neighborhood Hits	297	Shared Neighborhood Hits	144
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MILK1_MOUSE
θ value	3.0926 (rank : 322)	NC score	0.063550 (rank : 436)
Query Neighborhood Hits	438	Target Neighborhood Hits	788	Shared Neighborhood Hits	151
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PO121_HUMAN
θ value	3.0926 (rank : 323)	NC score	0.051542 (rank : 560)
Query Neighborhood Hits	438	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PRR12_HUMAN
θ value	3.0926 (rank : 324)	NC score	0.128693 (rank : 184)
Query Neighborhood Hits	438	Target Neighborhood Hits	460	Shared Neighborhood Hits	101
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RHG05_MOUSE
θ value	3.0926 (rank : 325)	NC score	0.034156 (rank : 611)
Query Neighborhood Hits	438	Target Neighborhood Hits	165	Shared Neighborhood Hits	19
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

S3TC1_HUMAN
θ value	3.0926 (rank : 326)	NC score	0.051239 (rank : 562)
Query Neighborhood Hits	438	Target Neighborhood Hits	78	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

SHLB1_MOUSE
θ value	3.0926 (rank : 327)	NC score	0.155939 (rank : 144)
Query Neighborhood Hits	438	Target Neighborhood Hits	101	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

TRI47_HUMAN
θ value	3.0926 (rank : 328)	NC score	0.007521 (rank : 662)
Query Neighborhood Hits	438	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TXK_MOUSE
θ value	3.0926 (rank : 329)	NC score	0.071066 (rank : 376)
Query Neighborhood Hits	438	Target Neighborhood Hits	980	Shared Neighborhood Hits	135
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

WASF4_HUMAN
θ value	3.0926 (rank : 330)	NC score	0.102904 (rank : 237)
Query Neighborhood Hits	438	Target Neighborhood Hits	282	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WIRE_MOUSE
θ value	3.0926 (rank : 331)	NC score	0.104605 (rank : 227)
Query Neighborhood Hits	438	Target Neighborhood Hits	310	Shared Neighborhood Hits	82
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ANK3_HUMAN
θ value	4.03905 (rank : 332)	NC score	0.028638 (rank : 621)
Query Neighborhood Hits	438	Target Neighborhood Hits	853	Shared Neighborhood Hits	71
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

DUS8_MOUSE
θ value	4.03905 (rank : 333)	NC score	0.015296 (rank : 654)
Query Neighborhood Hits	438	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

ERF_HUMAN
θ value	4.03905 (rank : 334)	NC score	0.020314 (rank : 643)
Query Neighborhood Hits	438	Target Neighborhood Hits	162	Shared Neighborhood Hits	27
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ES8L3_MOUSE
θ value	4.03905 (rank : 335)	NC score	0.221751 (rank : 111)
Query Neighborhood Hits	438	Target Neighborhood Hits	168	Shared Neighborhood Hits	127
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

LPP_MOUSE
θ value	4.03905 (rank : 336)	NC score	0.038780 (rank : 597)
Query Neighborhood Hits	438	Target Neighborhood Hits	247	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

M3K4_MOUSE
θ value	4.03905 (rank : 337)	NC score	0.016107 (rank : 651)
Query Neighborhood Hits	438	Target Neighborhood Hits	924	Shared Neighborhood Hits	47
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

MAML2_HUMAN
θ value	4.03905 (rank : 338)	NC score	0.044961 (rank : 576)
Query Neighborhood Hits	438	Target Neighborhood Hits	360	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

NCOA6_MOUSE
θ value	4.03905 (rank : 339)	NC score	0.121293 (rank : 195)
Query Neighborhood Hits	438	Target Neighborhood Hits	1076	Shared Neighborhood Hits	207
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PER2_MOUSE
θ value	4.03905 (rank : 340)	NC score	0.038938 (rank : 596)
Query Neighborhood Hits	438	Target Neighborhood Hits	325	Shared Neighborhood Hits	84
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PRGC2_HUMAN
θ value	4.03905 (rank : 341)	NC score	0.037343 (rank : 602)
Query Neighborhood Hits	438	Target Neighborhood Hits	272	Shared Neighborhood Hits	52
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

RBM16_HUMAN
θ value	4.03905 (rank : 342)	NC score	0.044322 (rank : 577)
Query Neighborhood Hits	438	Target Neighborhood Hits	300	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

SHC1_HUMAN
θ value	4.03905 (rank : 343)	NC score	0.070762 (rank : 380)
Query Neighborhood Hits	438	Target Neighborhood Hits	170	Shared Neighborhood Hits	59
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHLB1_HUMAN
θ value	4.03905 (rank : 344)	NC score	0.150320 (rank : 146)
Query Neighborhood Hits	438	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

VAX1_MOUSE
θ value	4.03905 (rank : 345)	NC score	0.005386 (rank : 666)
Query Neighborhood Hits	438	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	Q2NKI2, O88880	Gene names	Vax1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

WASF3_MOUSE
θ value	4.03905 (rank : 346)	NC score	0.085107 (rank : 306)
Query Neighborhood Hits	438	Target Neighborhood Hits	188	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

X3CL1_HUMAN
θ value	4.03905 (rank : 347)	NC score	0.035929 (rank : 606)
Query Neighborhood Hits	438	Target Neighborhood Hits	152	Shared Neighborhood Hits	25
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ZIM10_HUMAN
θ value	4.03905 (rank : 348)	NC score	0.070335 (rank : 383)
Query Neighborhood Hits	438	Target Neighborhood Hits	577	Shared Neighborhood Hits	133
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN628_MOUSE
θ value	4.03905 (rank : 349)	NC score	-0.006883 (rank : 678)
Query Neighborhood Hits	438	Target Neighborhood Hits	815	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

ADA12_MOUSE
θ value	5.27518 (rank : 350)	NC score	0.019156 (rank : 645)
Query Neighborhood Hits	438	Target Neighborhood Hits	474	Shared Neighborhood Hits	91
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

AMELY_HUMAN
θ value	5.27518 (rank : 351)	NC score	0.030288 (rank : 617)
Query Neighborhood Hits	438	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q99218, Q6RWT1	Gene names	AMELY, AMGL, AMGY
Domain Architecture
Description	Amelogenin, Y isoform precursor.

ANM2_HUMAN
θ value	5.27518 (rank : 352)	NC score	0.171167 (rank : 135)
Query Neighborhood Hits	438	Target Neighborhood Hits	175	Shared Neighborhood Hits	140
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	5.27518 (rank : 353)	NC score	0.164529 (rank : 139)
Query Neighborhood Hits	438	Target Neighborhood Hits	175	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANTR1_MOUSE
θ value	5.27518 (rank : 354)	NC score	0.052420 (rank : 550)
Query Neighborhood Hits	438	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ATX2L_HUMAN
θ value	5.27518 (rank : 355)	NC score	0.089831 (rank : 287)
Query Neighborhood Hits	438	Target Neighborhood Hits	443	Shared Neighborhood Hits	103
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BCL3_MOUSE
θ value	5.27518 (rank : 356)	NC score	0.023382 (rank : 633)
Query Neighborhood Hits	438	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CF055_MOUSE
θ value	5.27518 (rank : 357)	NC score	0.020205 (rank : 644)
Query Neighborhood Hits	438	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

CIC_HUMAN
θ value	5.27518 (rank : 358)	NC score	0.087121 (rank : 297)
Query Neighborhood Hits	438	Target Neighborhood Hits	992	Shared Neighborhood Hits	177
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO039_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.054529 (rank : 520)
Query Neighborhood Hits	438	Target Neighborhood Hits	264	Shared Neighborhood Hits	58
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CSKI2_MOUSE
θ value	5.27518 (rank : 360)	NC score	0.065981 (rank : 413)
Query Neighborhood Hits	438	Target Neighborhood Hits	812	Shared Neighborhood Hits	137
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

EGFB2_MOUSE
θ value	5.27518 (rank : 361)	NC score	0.000191 (rank : 674)
Query Neighborhood Hits	438	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

FMN2_HUMAN
θ value	5.27518 (rank : 362)	NC score	0.081742 (rank : 318)
Query Neighborhood Hits	438	Target Neighborhood Hits	484	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

HGS_MOUSE
θ value	5.27518 (rank : 363)	NC score	0.072769 (rank : 366)
Query Neighborhood Hits	438	Target Neighborhood Hits	589	Shared Neighborhood Hits	104
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

K1688_HUMAN
θ value	5.27518 (rank : 364)	NC score	0.053920 (rank : 528)
Query Neighborhood Hits	438	Target Neighborhood Hits	217	Shared Neighborhood Hits	55
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K1914_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.012514 (rank : 659)
Query Neighborhood Hits	438	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

LRTM1_MOUSE
θ value	5.27518 (rank : 366)	NC score	-0.002414 (rank : 677)
Query Neighborhood Hits	438	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K377, Q3UVX1	Gene names	Lrrtm1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

MEF2B_MOUSE
θ value	5.27518 (rank : 367)	NC score	0.039440 (rank : 591)
Query Neighborhood Hits	438	Target Neighborhood Hits	218	Shared Neighborhood Hits	58
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MKL1_HUMAN
θ value	5.27518 (rank : 368)	NC score	0.039001 (rank : 595)
Query Neighborhood Hits	438	Target Neighborhood Hits	232	Shared Neighborhood Hits	35
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

NFAT5_MOUSE
θ value	5.27518 (rank : 369)	NC score	0.018534 (rank : 647)
Query Neighborhood Hits	438	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

PARM1_MOUSE
θ value	5.27518 (rank : 370)	NC score	0.034271 (rank : 610)
Query Neighborhood Hits	438	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PDZD2_HUMAN
θ value	5.27518 (rank : 371)	NC score	0.040112 (rank : 587)
Query Neighborhood Hits	438	Target Neighborhood Hits	772	Shared Neighborhood Hits	99
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PER1_HUMAN
θ value	5.27518 (rank : 372)	NC score	0.035619 (rank : 607)
Query Neighborhood Hits	438	Target Neighborhood Hits	215	Shared Neighborhood Hits	41
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PO6F1_MOUSE
θ value	5.27518 (rank : 373)	NC score	0.036166 (rank : 605)
Query Neighborhood Hits	438	Target Neighborhood Hits	581	Shared Neighborhood Hits	88
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

RBM12_MOUSE
θ value	5.27518 (rank : 374)	NC score	0.052840 (rank : 546)
Query Neighborhood Hits	438	Target Neighborhood Hits	313	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

REEP3_MOUSE
θ value	5.27518 (rank : 375)	NC score	0.007844 (rank : 661)
Query Neighborhood Hits	438	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KK1, Q9CZM8, Q9D8G3	Gene names	Reep3, D10Ucla1
Domain Architecture	No domain graphic available
Description	Receptor expression-enhancing protein 3.

SF3A1_MOUSE
θ value	5.27518 (rank : 376)	NC score	0.062553 (rank : 443)
Query Neighborhood Hits	438	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SIN3A_HUMAN
θ value	5.27518 (rank : 377)	NC score	0.039064 (rank : 593)
Query Neighborhood Hits	438	Target Neighborhood Hits	180	Shared Neighborhood Hits	47
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

TAU_MOUSE
θ value	5.27518 (rank : 378)	NC score	0.045781 (rank : 575)
Query Neighborhood Hits	438	Target Neighborhood Hits	502	Shared Neighborhood Hits	86
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

UBQL4_HUMAN
θ value	5.27518 (rank : 379)	NC score	0.018343 (rank : 648)
Query Neighborhood Hits	438	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

WIRE_HUMAN
θ value	5.27518 (rank : 380)	NC score	0.110958 (rank : 213)
Query Neighborhood Hits	438	Target Neighborhood Hits	329	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ABCA7_MOUSE
θ value	6.88961 (rank : 381)	NC score	0.000911 (rank : 672)
Query Neighborhood Hits	438	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

ABL1_HUMAN
θ value	6.88961 (rank : 382)	NC score	0.068293 (rank : 397)
Query Neighborhood Hits	438	Target Neighborhood Hits	1220	Shared Neighborhood Hits	149
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	6.88961 (rank : 383)	NC score	0.069615 (rank : 388)
Query Neighborhood Hits	438	Target Neighborhood Hits	1178	Shared Neighborhood Hits	151
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CBP_MOUSE
θ value	6.88961 (rank : 384)	NC score	0.104558 (rank : 228)
Query Neighborhood Hits	438	Target Neighborhood Hits	1051	Shared Neighborhood Hits	182
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CF055_HUMAN
θ value	6.88961 (rank : 385)	NC score	0.020602 (rank : 642)
Query Neighborhood Hits	438	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP79, Q9H0R2, Q9H3K9, Q9P0Q0	Gene names	C6orf55
Domain Architecture
Description	Protein C6orf55 (Dopamine-responsive protein DRG-1).

CUTL1_HUMAN
θ value	6.88961 (rank : 386)	NC score	0.018935 (rank : 646)
Query Neighborhood Hits	438	Target Neighborhood Hits	1574	Shared Neighborhood Hits	82
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DIAP1_HUMAN
θ value	6.88961 (rank : 387)	NC score	0.053656 (rank : 534)
Query Neighborhood Hits	438	Target Neighborhood Hits	784	Shared Neighborhood Hits	74
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

EGR1_MOUSE
θ value	6.88961 (rank : 388)	NC score	-0.001134 (rank : 676)
Query Neighborhood Hits	438	Target Neighborhood Hits	816	Shared Neighborhood Hits	44
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

ENAH_MOUSE
θ value	6.88961 (rank : 389)	NC score	0.096285 (rank : 259)
Query Neighborhood Hits	438	Target Neighborhood Hits	919	Shared Neighborhood Hits	115
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GAK3_HUMAN
θ value	6.88961 (rank : 390)	NC score	0.101376 (rank : 244)
Query Neighborhood Hits	438	Target Neighborhood Hits	182	Shared Neighborhood Hits	53
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HCN2_MOUSE
θ value	6.88961 (rank : 391)	NC score	0.023050 (rank : 636)
Query Neighborhood Hits	438	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HGS_HUMAN
θ value	6.88961 (rank : 392)	NC score	0.068365 (rank : 396)
Query Neighborhood Hits	438	Target Neighborhood Hits	517	Shared Neighborhood Hits	83
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

IRS2_MOUSE
θ value	6.88961 (rank : 393)	NC score	0.035060 (rank : 608)
Query Neighborhood Hits	438	Target Neighborhood Hits	248	Shared Neighborhood Hits	43
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

ITK_HUMAN
θ value	6.88961 (rank : 394)	NC score	0.064758 (rank : 427)
Query Neighborhood Hits	438	Target Neighborhood Hits	1016	Shared Neighborhood Hits	132
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

K0355_HUMAN
θ value	6.88961 (rank : 395)	NC score	0.027856 (rank : 623)
Query Neighborhood Hits	438	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	O15063	Gene names	KIAA0355
Domain Architecture	No domain graphic available
Description	Protein KIAA0355.

K1802_HUMAN
θ value	6.88961 (rank : 396)	NC score	0.070498 (rank : 382)
Query Neighborhood Hits	438	Target Neighborhood Hits	1378	Shared Neighborhood Hits	182
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1B16_MOUSE
θ value	6.88961 (rank : 397)	NC score	0.000391 (rank : 673)
Query Neighborhood Hits	438	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

MAGD1_HUMAN
θ value	6.88961 (rank : 398)	NC score	0.022918 (rank : 637)
Query Neighborhood Hits	438	Target Neighborhood Hits	130	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

MCM4_MOUSE
θ value	6.88961 (rank : 399)	NC score	0.004551 (rank : 668)
Query Neighborhood Hits	438	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P49717, O89056	Gene names	Mcm4, Cdc21, Mcmd4
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MEGF9_HUMAN
θ value	6.88961 (rank : 400)	NC score	0.021116 (rank : 641)
Query Neighborhood Hits	438	Target Neighborhood Hits	557	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PDC6I_HUMAN
θ value	6.88961 (rank : 401)	NC score	0.060051 (rank : 462)
Query Neighborhood Hits	438	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PI5PA_MOUSE
θ value	6.88961 (rank : 402)	NC score	0.042756 (rank : 579)
Query Neighborhood Hits	438	Target Neighborhood Hits	331	Shared Neighborhood Hits	75
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PTK6_MOUSE
θ value	6.88961 (rank : 403)	NC score	0.076610 (rank : 347)
Query Neighborhood Hits	438	Target Neighborhood Hits	1026	Shared Neighborhood Hits	150
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

RAVR1_MOUSE
θ value	6.88961 (rank : 404)	NC score	0.017706 (rank : 649)
Query Neighborhood Hits	438	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

RCOR2_MOUSE
θ value	6.88961 (rank : 405)	NC score	0.037985 (rank : 601)
Query Neighborhood Hits	438	Target Neighborhood Hits	107	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

SH22A_MOUSE
θ value	6.88961 (rank : 406)	NC score	0.060299 (rank : 459)
Query Neighborhood Hits	438	Target Neighborhood Hits	179	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SHAN1_HUMAN
θ value	6.88961 (rank : 407)	NC score	0.134154 (rank : 171)
Query Neighborhood Hits	438	Target Neighborhood Hits	1041	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SPEG_HUMAN
θ value	6.88961 (rank : 408)	NC score	0.031701 (rank : 615)
Query Neighborhood Hits	438	Target Neighborhood Hits	1762	Shared Neighborhood Hits	157
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TAF4_HUMAN
θ value	6.88961 (rank : 409)	NC score	0.120803 (rank : 196)
Query Neighborhood Hits	438	Target Neighborhood Hits	687	Shared Neighborhood Hits	115
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TREF1_MOUSE
θ value	6.88961 (rank : 410)	NC score	0.023283 (rank : 634)
Query Neighborhood Hits	438	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

TXK_HUMAN
θ value	6.88961 (rank : 411)	NC score	0.065980 (rank : 414)
Query Neighborhood Hits	438	Target Neighborhood Hits	971	Shared Neighborhood Hits	126
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

VASP_HUMAN
θ value	6.88961 (rank : 412)	NC score	0.047417 (rank : 573)
Query Neighborhood Hits	438	Target Neighborhood Hits	201	Shared Neighborhood Hits	48
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WBP2_HUMAN
θ value	6.88961 (rank : 413)	NC score	0.054359 (rank : 524)
Query Neighborhood Hits	438	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	Q969T9, O95638	Gene names	WBP2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

WNK2_HUMAN
θ value	6.88961 (rank : 414)	NC score	0.046663 (rank : 574)
Query Neighborhood Hits	438	Target Neighborhood Hits	1407	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZO1_HUMAN
θ value	6.88961 (rank : 415)	NC score	0.032275 (rank : 614)
Query Neighborhood Hits	438	Target Neighborhood Hits	474	Shared Neighborhood Hits	79
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	6.88961 (rank : 416)	NC score	0.027616 (rank : 624)
Query Neighborhood Hits	438	Target Neighborhood Hits	453	Shared Neighborhood Hits	63
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ACON_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.006319 (rank : 664)
Query Neighborhood Hits	438	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q99798, O75809	Gene names	ACO2
Domain Architecture
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

BSN_HUMAN
θ value	8.99809 (rank : 418)	NC score	0.086424 (rank : 300)
Query Neighborhood Hits	438	Target Neighborhood Hits	1537	Shared Neighborhood Hits	171
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CRTC1_HUMAN
θ value	8.99809 (rank : 419)	NC score	0.080626 (rank : 324)
Query Neighborhood Hits	438	Target Neighborhood Hits	319	Shared Neighborhood Hits	100
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CX045_HUMAN
θ value	8.99809 (rank : 420)	NC score	0.015600 (rank : 652)
Query Neighborhood Hits	438	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5U8, Q5JXY9	Gene names	CXorf45
Domain Architecture	No domain graphic available
Description	Protein CXorf45.

DLX5_MOUSE
θ value	8.99809 (rank : 421)	NC score	0.005617 (rank : 665)
Query Neighborhood Hits	438	Target Neighborhood Hits	434	Shared Neighborhood Hits	35
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

K0310_HUMAN
θ value	8.99809 (rank : 422)	NC score	0.079589 (rank : 331)
Query Neighborhood Hits	438	Target Neighborhood Hits	420	Shared Neighborhood Hits	96
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MAGI2_MOUSE
θ value	8.99809 (rank : 423)	NC score	0.014835 (rank : 655)
Query Neighborhood Hits	438	Target Neighborhood Hits	370	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAP2_MOUSE
θ value	8.99809 (rank : 424)	NC score	0.016742 (rank : 650)
Query Neighborhood Hits	438	Target Neighborhood Hits	342	Shared Neighborhood Hits	33
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

NGEF_MOUSE
θ value	8.99809 (rank : 425)	NC score	0.111162 (rank : 212)
Query Neighborhood Hits	438	Target Neighborhood Hits	228	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PCQAP_MOUSE
θ value	8.99809 (rank : 426)	NC score	0.061966 (rank : 448)
Query Neighborhood Hits	438	Target Neighborhood Hits	506	Shared Neighborhood Hits	77
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PLS3_MOUSE
θ value	8.99809 (rank : 427)	NC score	0.029191 (rank : 619)
Query Neighborhood Hits	438	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIZ9	Gene names	Plscr3
Domain Architecture
Description	Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3).

R3HD1_HUMAN
θ value	8.99809 (rank : 428)	NC score	0.061170 (rank : 453)
Query Neighborhood Hits	438	Target Neighborhood Hits	203	Shared Neighborhood Hits	50
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

RCOR2_HUMAN
θ value	8.99809 (rank : 429)	NC score	0.036830 (rank : 603)
Query Neighborhood Hits	438	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RHG05_HUMAN
θ value	8.99809 (rank : 430)	NC score	0.030761 (rank : 616)
Query Neighborhood Hits	438	Target Neighborhood Hits	158	Shared Neighborhood Hits	18
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

ROBO3_MOUSE
θ value	8.99809 (rank : 431)	NC score	0.004229 (rank : 669)
Query Neighborhood Hits	438	Target Neighborhood Hits	524	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

SAM68_HUMAN
θ value	8.99809 (rank : 432)	NC score	0.022592 (rank : 638)
Query Neighborhood Hits	438	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SSBP3_HUMAN
θ value	8.99809 (rank : 433)	NC score	0.039808 (rank : 588)
Query Neighborhood Hits	438	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	8.99809 (rank : 434)	NC score	0.039808 (rank : 589)
Query Neighborhood Hits	438	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

TULP4_HUMAN
θ value	8.99809 (rank : 435)	NC score	0.050756 (rank : 568)
Query Neighborhood Hits	438	Target Neighborhood Hits	426	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

WASF2_HUMAN
θ value	8.99809 (rank : 436)	NC score	0.110697 (rank : 215)
Query Neighborhood Hits	438	Target Neighborhood Hits	280	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WDR7_MOUSE
θ value	8.99809 (rank : 437)	NC score	0.004736 (rank : 667)
Query Neighborhood Hits	438	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

ZN645_HUMAN
θ value	8.99809 (rank : 438)	NC score	0.068947 (rank : 391)
Query Neighborhood Hits	438	Target Neighborhood Hits	265	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

3BP1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.066756 (rank : 407)
Query Neighborhood Hits	438	Target Neighborhood Hits	376	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.050801 (rank : 567)
Query Neighborhood Hits	438	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AB1IP_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.051767 (rank : 559)
Query Neighborhood Hits	438	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ABI3_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.264449 (rank : 91)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	159
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.262897 (rank : 93)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABL2_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.062779 (rank : 440)
Query Neighborhood Hits	438	Target Neighborhood Hits	1045	Shared Neighborhood Hits	125
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABR_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.057510 (rank : 482)
Query Neighborhood Hits	438	Target Neighborhood Hits	166	Shared Neighborhood Hits	37
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ALEX_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.079841 (rank : 328)
Query Neighborhood Hits	438	Target Neighborhood Hits	361	Shared Neighborhood Hits	84
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AMPH_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.101503 (rank : 243)
Query Neighborhood Hits	438	Target Neighborhood Hits	455	Shared Neighborhood Hits	121
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.090928 (rank : 280)
Query Neighborhood Hits	438	Target Neighborhood Hits	291	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANK2_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.053378 (rank : 537)
Query Neighborhood Hits	438	Target Neighborhood Hits	1615	Shared Neighborhood Hits	170
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

APS_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.061182 (rank : 452)
Query Neighborhood Hits	438	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

ARHG1_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.060694 (rank : 457)
Query Neighborhood Hits	438	Target Neighborhood Hits	176	Shared Neighborhood Hits	26
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.057196 (rank : 487)
Query Neighborhood Hits	438	Target Neighborhood Hits	266	Shared Neighborhood Hits	50
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.050929 (rank : 566)
Query Neighborhood Hits	438	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.050324 (rank : 571)
Query Neighborhood Hits	438	Target Neighborhood Hits	120	Shared Neighborhood Hits	24
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.082808 (rank : 315)
Query Neighborhood Hits	438	Target Neighborhood Hits	82	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.082397 (rank : 316)
Query Neighborhood Hits	438	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.184757 (rank : 129)
Query Neighborhood Hits	438	Target Neighborhood Hits	185	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG5_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.104855 (rank : 226)
Query Neighborhood Hits	438	Target Neighborhood Hits	172	Shared Neighborhood Hits	77
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG8_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.075403 (rank : 355)
Query Neighborhood Hits	438	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.078613 (rank : 336)
Query Neighborhood Hits	438	Target Neighborhood Hits	79	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGA_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.067651 (rank : 401)
Query Neighborhood Hits	438	Target Neighborhood Hits	187	Shared Neighborhood Hits	26
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.073067 (rank : 364)
Query Neighborhood Hits	438	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.063563 (rank : 435)
Query Neighborhood Hits	438	Target Neighborhood Hits	375	Shared Neighborhood Hits	43
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.062657 (rank : 442)
Query Neighborhood Hits	438	Target Neighborhood Hits	351	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.062518 (rank : 445)
Query Neighborhood Hits	438	Target Neighborhood Hits	344	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.071687 (rank : 370)
Query Neighborhood Hits	438	Target Neighborhood Hits	214	Shared Neighborhood Hits	52
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.078194 (rank : 340)
Query Neighborhood Hits	438	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.090429 (rank : 284)
Query Neighborhood Hits	438	Target Neighborhood Hits	152	Shared Neighborhood Hits	56
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARI1B_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.105898 (rank : 223)
Query Neighborhood Hits	438	Target Neighborhood Hits	567	Shared Neighborhood Hits	125
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

AUTS2_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.058416 (rank : 473)
Query Neighborhood Hits	438	Target Neighborhood Hits	342	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAG3_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.071992 (rank : 369)
Query Neighborhood Hits	438	Target Neighborhood Hits	513	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BAIP2_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.053014 (rank : 544)
Query Neighborhood Hits	438	Target Neighborhood Hits	192	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.054755 (rank : 517)
Query Neighborhood Hits	438	Target Neighborhood Hits	185	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BAT2_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.114213 (rank : 207)
Query Neighborhood Hits	438	Target Neighborhood Hits	947	Shared Neighborhood Hits	164
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.055001 (rank : 513)
Query Neighborhood Hits	438	Target Neighborhood Hits	518	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.054162 (rank : 526)
Query Neighborhood Hits	438	Target Neighborhood Hits	744	Shared Neighborhood Hits	117
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BCR_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.065404 (rank : 422)
Query Neighborhood Hits	438	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BI2L1_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.070293 (rank : 384)
Query Neighborhood Hits	438	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BI2L1_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.055627 (rank : 509)
Query Neighborhood Hits	438	Target Neighborhood Hits	197	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BIN1_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.092866 (rank : 274)
Query Neighborhood Hits	438	Target Neighborhood Hits	335	Shared Neighborhood Hits	103
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.081282 (rank : 320)
Query Neighborhood Hits	438	Target Neighborhood Hits	283	Shared Neighborhood Hits	93
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BLK_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.074239 (rank : 360)
Query Neighborhood Hits	438	Target Neighborhood Hits	992	Shared Neighborhood Hits	131
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

CD2_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.079102 (rank : 334)
Query Neighborhood Hits	438	Target Neighborhood Hits	504	Shared Neighborhood Hits	129
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CECR2_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.057050 (rank : 491)
Query Neighborhood Hits	438	Target Neighborhood Hits	543	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CEL_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.081237 (rank : 322)
Query Neighborhood Hits	438	Target Neighborhood Hits	896	Shared Neighborhood Hits	171
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CHIN_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.053695 (rank : 531)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.054504 (rank : 521)
Query Neighborhood Hits	438	Target Neighborhood Hits	229	Shared Neighborhood Hits	51
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.052551 (rank : 549)
Query Neighborhood Hits	438	Target Neighborhood Hits	220	Shared Neighborhood Hits	48
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CIC_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.059877 (rank : 463)
Query Neighborhood Hits	438	Target Neighborhood Hits	742	Shared Neighborhood Hits	129
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIKS_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.061460 (rank : 451)
Query Neighborhood Hits	438	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

CIP4_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.092636 (rank : 275)
Query Neighborhood Hits	438	Target Neighborhood Hits	374	Shared Neighborhood Hits	74
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CIZ1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.058759 (rank : 470)
Query Neighborhood Hits	438	Target Neighborhood Hits	359	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ078_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.067866 (rank : 399)
Query Neighborhood Hits	438	Target Neighborhood Hits	559	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.089435 (rank : 289)
Query Neighborhood Hits	438	Target Neighborhood Hits	408	Shared Neighborhood Hits	116
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.096344 (rank : 257)
Query Neighborhood Hits	438	Target Neighborhood Hits	267	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.095372 (rank : 264)
Query Neighborhood Hits	438	Target Neighborhood Hits	233	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.080118 (rank : 327)
Query Neighborhood Hits	438	Target Neighborhood Hits	385	Shared Neighborhood Hits	68
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO039_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.074941 (rank : 356)
Query Neighborhood Hits	438	Target Neighborhood Hits	445	Shared Neighborhood Hits	118
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CRSP2_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.061729 (rank : 449)
Query Neighborhood Hits	438	Target Neighborhood Hits	380	Shared Neighborhood Hits	99
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CS016_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.076010 (rank : 352)
Query Neighborhood Hits	438	Target Neighborhood Hits	310	Shared Neighborhood Hits	66
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSKI2_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.059085 (rank : 468)
Query Neighborhood Hits	438	Target Neighborhood Hits	747	Shared Neighborhood Hits	105
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSK_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.070932 (rank : 378)
Query Neighborhood Hits	438	Target Neighborhood Hits	1009	Shared Neighborhood Hits	132
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.070895 (rank : 379)
Query Neighborhood Hits	438	Target Neighborhood Hits	1009	Shared Neighborhood Hits	132
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

DAPP1_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.064583 (rank : 430)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.064869 (rank : 426)
Query Neighborhood Hits	438	Target Neighborhood Hits	225	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DBNL_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.258826 (rank : 98)
Query Neighborhood Hits	438	Target Neighborhood Hits	244	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.258906 (rank : 97)
Query Neighborhood Hits	438	Target Neighborhood Hits	306	Shared Neighborhood Hits	147
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DIDO1_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.052950 (rank : 545)
Query Neighborhood Hits	438	Target Neighborhood Hits	960	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DOCK1_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.087689 (rank : 294)
Query Neighborhood Hits	438	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

ECT2_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.064148 (rank : 432)
Query Neighborhood Hits	438	Target Neighborhood Hits	98	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.066237 (rank : 409)
Query Neighborhood Hits	438	Target Neighborhood Hits	98	Shared Neighborhood Hits	23
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EM55_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.054765 (rank : 516)
Query Neighborhood Hits	438	Target Neighborhood Hits	228	Shared Neighborhood Hits	90
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.052329 (rank : 552)
Query Neighborhood Hits	438	Target Neighborhood Hits	221	Shared Neighborhood Hits	85
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

ENAM_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.050277 (rank : 572)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

ES8L1_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.147798 (rank : 150)
Query Neighborhood Hits	438	Target Neighborhood Hits	162	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L1_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.144949 (rank : 154)
Query Neighborhood Hits	438	Target Neighborhood Hits	143	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L3_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.176485 (rank : 133)
Query Neighborhood Hits	438	Target Neighborhood Hits	206	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FA47A_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.091328 (rank : 279)
Query Neighborhood Hits	438	Target Neighborhood Hits	451	Shared Neighborhood Hits	114
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FGD1_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.068154 (rank : 398)
Query Neighborhood Hits	438	Target Neighborhood Hits	387	Shared Neighborhood Hits	78
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.055688 (rank : 507)
Query Neighborhood Hits	438	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.053430 (rank : 536)
Query Neighborhood Hits	438	Target Neighborhood Hits	163	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.054697 (rank : 519)
Query Neighborhood Hits	438	Target Neighborhood Hits	249	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.058555 (rank : 471)
Query Neighborhood Hits	438	Target Neighborhood Hits	257	Shared Neighborhood Hits	30
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.056346 (rank : 499)
Query Neighborhood Hits	438	Target Neighborhood Hits	219	Shared Neighborhood Hits	29
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.056698 (rank : 494)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FMN2_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.064695 (rank : 429)
Query Neighborhood Hits	438	Target Neighborhood Hits	349	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMNL_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.062693 (rank : 441)
Query Neighborhood Hits	438	Target Neighborhood Hits	529	Shared Neighborhood Hits	87
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FYB_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.055928 (rank : 502)
Query Neighborhood Hits	438	Target Neighborhood Hits	379	Shared Neighborhood Hits	81
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GA2L2_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.055972 (rank : 501)
Query Neighborhood Hits	438	Target Neighborhood Hits	395	Shared Neighborhood Hits	103
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GAB1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.057502 (rank : 483)
Query Neighborhood Hits	438	Target Neighborhood Hits	279	Shared Neighborhood Hits	79
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.055008 (rank : 512)
Query Neighborhood Hits	438	Target Neighborhood Hits	233	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAK13_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.075760 (rank : 353)
Query Neighborhood Hits	438	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	P62686	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK14_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.078378 (rank : 339)
Query Neighborhood Hits	438	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P62687	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_16p3.3 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK15_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.084532 (rank : 311)
Query Neighborhood Hits	438	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P62688	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(I) Gag protein).

GAK17_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.085016 (rank : 308)
Query Neighborhood Hits	438	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

GAK18_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.093742 (rank : 269)
Query Neighborhood Hits	438	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK19_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.081817 (rank : 317)
Query Neighborhood Hits	438	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK9_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.084923 (rank : 309)
Query Neighborhood Hits	438	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

GGN_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.067370 (rank : 402)
Query Neighborhood Hits	438	Target Neighborhood Hits	269	Shared Neighborhood Hits	65
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.085050 (rank : 307)
Query Neighborhood Hits	438	Target Neighborhood Hits	311	Shared Neighborhood Hits	66
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GNRP_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.053020 (rank : 543)
Query Neighborhood Hits	438	Target Neighborhood Hits	191	Shared Neighborhood Hits	24
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GPS2_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.065156 (rank : 424)
Query Neighborhood Hits	438	Target Neighborhood Hits	459	Shared Neighborhood Hits	84
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GRB10_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.052017 (rank : 557)
Query Neighborhood Hits	438	Target Neighborhood Hits	156	Shared Neighborhood Hits	49
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB14_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.062903 (rank : 437)
Query Neighborhood Hits	438	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB14_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.063805 (rank : 434)
Query Neighborhood Hits	438	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.053667 (rank : 533)
Query Neighborhood Hits	438	Target Neighborhood Hits	156	Shared Neighborhood Hits	52
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.058321 (rank : 475)
Query Neighborhood Hits	438	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

HAPIP_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.064756 (rank : 428)
Query Neighborhood Hits	438	Target Neighborhood Hits	350	Shared Neighborhood Hits	28
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HSH2D_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.053281 (rank : 538)
Query Neighborhood Hits	438	Target Neighborhood Hits	159	Shared Neighborhood Hits	39
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

IGEB_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.053062 (rank : 541)
Query Neighborhood Hits	438	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P03975	Gene names	Iap
Domain Architecture
Description	IgE-binding protein.

ITK_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.057333 (rank : 486)
Query Neighborhood Hits	438	Target Neighborhood Hits	985	Shared Neighborhood Hits	116
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JIP1_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.065491 (rank : 420)
Query Neighborhood Hits	438	Target Neighborhood Hits	271	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.065033 (rank : 425)
Query Neighborhood Hits	438	Target Neighborhood Hits	259	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP2_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.059708 (rank : 465)
Query Neighborhood Hits	438	Target Neighborhood Hits	288	Shared Neighborhood Hits	87
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.051031 (rank : 565)
Query Neighborhood Hits	438	Target Neighborhood Hits	144	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

LBC_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.054722 (rank : 518)
Query Neighborhood Hits	438	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LCK_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.067787 (rank : 400)
Query Neighborhood Hits	438	Target Neighborhood Hits	987	Shared Neighborhood Hits	116
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.067043 (rank : 405)
Query Neighborhood Hits	438	Target Neighborhood Hits	981	Shared Neighborhood Hits	114
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LCP2_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.122598 (rank : 193)
Query Neighborhood Hits	438	Target Neighborhood Hits	531	Shared Neighborhood Hits	158
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LCP2_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.062103 (rank : 446)
Query Neighborhood Hits	438	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LNK_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.056697 (rank : 495)
Query Neighborhood Hits	438	Target Neighborhood Hits	151	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LNK_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.053023 (rank : 542)
Query Neighborhood Hits	438	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LPP_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.083948 (rank : 313)
Query Neighborhood Hits	438	Target Neighborhood Hits	775	Shared Neighborhood Hits	175
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LR37A_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.052135 (rank : 555)
Query Neighborhood Hits	438	Target Neighborhood Hits	720	Shared Neighborhood Hits	111
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MCF2_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.079465 (rank : 332)
Query Neighborhood Hits	438	Target Neighborhood Hits	166	Shared Neighborhood Hits	26
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MDC1_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.097655 (rank : 253)
Query Neighborhood Hits	438	Target Neighborhood Hits	1446	Shared Neighborhood Hits	180
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.093490 (rank : 270)
Query Neighborhood Hits	438	Target Neighborhood Hits	998	Shared Neighborhood Hits	164
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MINT_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.056026 (rank : 500)
Query Neighborhood Hits	438	Target Neighborhood Hits	1291	Shared Neighborhood Hits	124
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.065807 (rank : 418)
Query Neighborhood Hits	438	Target Neighborhood Hits	1514	Shared Neighborhood Hits	172
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MISS_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.111726 (rank : 211)
Query Neighborhood Hits	438	Target Neighborhood Hits	444	Shared Neighborhood Hits	138
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL4_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.079327 (rank : 333)
Query Neighborhood Hits	438	Target Neighborhood Hits	722	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MTSS1_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.065317 (rank : 423)
Query Neighborhood Hits	438	Target Neighborhood Hits	592	Shared Neighborhood Hits	114
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MYO15_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.053139 (rank : 540)
Query Neighborhood Hits	438	Target Neighborhood Hits	467	Shared Neighborhood Hits	119
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NACAM_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.130043 (rank : 182)
Query Neighborhood Hits	438	Target Neighborhood Hits	1866	Shared Neighborhood Hits	238
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.130903 (rank : 179)
Query Neighborhood Hits	438	Target Neighborhood Hits	1202	Shared Neighborhood Hits	210
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NFH_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.053230 (rank : 539)
Query Neighborhood Hits	438	Target Neighborhood Hits	2247	Shared Neighborhood Hits	190
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NGEF_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.106592 (rank : 222)
Query Neighborhood Hits	438	Target Neighborhood Hits	166	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

OBF1_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.064386 (rank : 431)
Query Neighborhood Hits	438	Target Neighborhood Hits	203	Shared Neighborhood Hits	77
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

P55G_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.057087 (rank : 490)
Query Neighborhood Hits	438	Target Neighborhood Hits	451	Shared Neighborhood Hits	57
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.055782 (rank : 505)
Query Neighborhood Hits	438	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85A_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.091956 (rank : 277)
Query Neighborhood Hits	438	Target Neighborhood Hits	479	Shared Neighborhood Hits	100
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.096437 (rank : 256)
Query Neighborhood Hits	438	Target Neighborhood Hits	435	Shared Neighborhood Hits	104
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.077810 (rank : 342)
Query Neighborhood Hits	438	Target Neighborhood Hits	543	Shared Neighborhood Hits	88
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.071421 (rank : 371)
Query Neighborhood Hits	438	Target Neighborhood Hits	519	Shared Neighborhood Hits	80
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCQAP_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.071126 (rank : 373)
Query Neighborhood Hits	438	Target Neighborhood Hits	549	Shared Neighborhood Hits	86
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PDC6I_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.053831 (rank : 529)
Query Neighborhood Hits	438	Target Neighborhood Hits	275	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PELP1_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.051298 (rank : 561)
Query Neighborhood Hits	438	Target Neighborhood Hits	596	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.078428 (rank : 337)
Query Neighborhood Hits	438	Target Neighborhood Hits	709	Shared Neighborhood Hits	122
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PI5PA_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.070582 (rank : 381)
Query Neighborhood Hits	438	Target Neighborhood Hits	749	Shared Neighborhood Hits	162
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHG1_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.091363 (rank : 278)
Query Neighborhood Hits	438	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PKHG4_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.054480 (rank : 522)
Query Neighborhood Hits	438	Target Neighborhood Hits	200	Shared Neighborhood Hits	37
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PPIP2_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.072778 (rank : 365)
Query Neighborhood Hits	438	Target Neighborhood Hits	254	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

PPIP2_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.069636 (rank : 387)
Query Neighborhood Hits	438	Target Neighborhood Hits	308	Shared Neighborhood Hits	21
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PRB3_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.095725 (rank : 260)
Query Neighborhood Hits	438	Target Neighborhood Hits	318	Shared Neighborhood Hits	66
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PREX1_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.086327 (rank : 302)
Query Neighborhood Hits	438	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRG4_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.061717 (rank : 450)
Query Neighborhood Hits	438	Target Neighborhood Hits	764	Shared Neighborhood Hits	98
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRPC_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.058381 (rank : 474)
Query Neighborhood Hits	438	Target Neighborhood Hits	165	Shared Neighborhood Hits	34
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRR13_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.074781 (rank : 358)
Query Neighborhood Hits	438	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.080322 (rank : 326)
Query Neighborhood Hits	438	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR8_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.057465 (rank : 484)
Query Neighborhood Hits	438	Target Neighborhood Hits	217	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PSL1_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.065411 (rank : 421)
Query Neighborhood Hits	438	Target Neighborhood Hits	650	Shared Neighborhood Hits	143
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RASA1_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.076657 (rank : 346)
Query Neighborhood Hits	438	Target Neighborhood Hits	258	Shared Neighborhood Hits	65
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RGNEF_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.056431 (rank : 498)
Query Neighborhood Hits	438	Target Neighborhood Hits	641	Shared Neighborhood Hits	53
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RHG09_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.051045 (rank : 564)
Query Neighborhood Hits	438	Target Neighborhood Hits	186	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RTP3_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.058423 (rank : 472)
Query Neighborhood Hits	438	Target Neighborhood Hits	374	Shared Neighborhood Hits	94
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SAPS1_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.089216 (rank : 292)
Query Neighborhood Hits	438	Target Neighborhood Hits	704	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SASH1_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.061995 (rank : 447)
Query Neighborhood Hits	438	Target Neighborhood Hits	292	Shared Neighborhood Hits	92
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SASH1_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.059709 (rank : 464)
Query Neighborhood Hits	438	Target Neighborhood Hits	263	Shared Neighborhood Hits	77
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SC24A_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.069209 (rank : 390)
Query Neighborhood Hits	438	Target Neighborhood Hits	394	Shared Neighborhood Hits	120
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SC24C_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.095697 (rank : 261)
Query Neighborhood Hits	438	Target Neighborhood Hits	662	Shared Neighborhood Hits	162
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SELPL_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.068366 (rank : 395)
Query Neighborhood Hits	438	Target Neighborhood Hits	588	Shared Neighborhood Hits	117
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SET1A_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.066199 (rank : 410)
Query Neighborhood Hits	438	Target Neighborhood Hits	690	Shared Neighborhood Hits	85
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF01_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.092953 (rank : 273)
Query Neighborhood Hits	438	Target Neighborhood Hits	287	Shared Neighborhood Hits	74
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.078970 (rank : 335)
Query Neighborhood Hits	438	Target Neighborhood Hits	240	Shared Neighborhood Hits	61
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A1_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.056604 (rank : 497)
Query Neighborhood Hits	438	Target Neighborhood Hits	199	Shared Neighborhood Hits	47
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A2_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.135974 (rank : 167)
Query Neighborhood Hits	438	Target Neighborhood Hits	263	Shared Neighborhood Hits	70
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.136496 (rank : 163)
Query Neighborhood Hits	438	Target Neighborhood Hits	247	Shared Neighborhood Hits	66
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFR15_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.060181 (rank : 461)
Query Neighborhood Hits	438	Target Neighborhood Hits	368	Shared Neighborhood Hits	67
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SH21B_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.065841 (rank : 416)
Query Neighborhood Hits	438	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.066973 (rank : 406)
Query Neighborhood Hits	438	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.126817 (rank : 187)
Query Neighborhood Hits	438	Target Neighborhood Hits	446	Shared Neighborhood Hits	136
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SHB_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.055642 (rank : 508)
Query Neighborhood Hits	438	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHB_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.057608 (rank : 481)
Query Neighborhood Hits	438	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC1_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.058300 (rank : 476)
Query Neighborhood Hits	438	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.057383 (rank : 485)
Query Neighborhood Hits	438	Target Neighborhood Hits	170	Shared Neighborhood Hits	55
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.057100 (rank : 489)
Query Neighborhood Hits	438	Target Neighborhood Hits	144	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.056889 (rank : 493)
Query Neighborhood Hits	438	Target Neighborhood Hits	155	Shared Neighborhood Hits	45
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.060960 (rank : 456)
Query Neighborhood Hits	438	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHD_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.057756 (rank : 479)
Query Neighborhood Hits	438	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHD_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.055721 (rank : 506)
Query Neighborhood Hits	438	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.058170 (rank : 478)
Query Neighborhood Hits	438	Target Neighborhood Hits	164	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHE_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.059032 (rank : 469)
Query Neighborhood Hits	438	Target Neighborhood Hits	169	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHLB2_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.117751 (rank : 202)
Query Neighborhood Hits	438	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.119136 (rank : 199)
Query Neighborhood Hits	438	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SLAP1_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.089701 (rank : 288)
Query Neighborhood Hits	438	Target Neighborhood Hits	113	Shared Neighborhood Hits	44
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.087529 (rank : 295)
Query Neighborhood Hits	438	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.102418 (rank : 240)
Query Neighborhood Hits	438	Target Neighborhood Hits	139	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.099479 (rank : 249)
Query Neighborhood Hits	438	Target Neighborhood Hits	136	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SLY_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.073096 (rank : 363)
Query Neighborhood Hits	438	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.083158 (rank : 314)
Query Neighborhood Hits	438	Target Neighborhood Hits	108	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SMR3A_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.064063 (rank : 433)
Query Neighborhood Hits	438	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SNPC4_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.056627 (rank : 496)
Query Neighborhood Hits	438	Target Neighborhood Hits	589	Shared Neighborhood Hits	121
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SNX9_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.138409 (rank : 159)
Query Neighborhood Hits	438	Target Neighborhood Hits	148	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SNX9_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.126515 (rank : 190)
Query Neighborhood Hits	438	Target Neighborhood Hits	141	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

SON_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.086419 (rank : 301)
Query Neighborhood Hits	438	Target Neighborhood Hits	957	Shared Neighborhood Hits	129
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR1B_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.059270 (rank : 467)
Query Neighborhood Hits	438	Target Neighborhood Hits	395	Shared Neighborhood Hits	109
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SRMS_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.054879 (rank : 515)
Query Neighborhood Hits	438	Target Neighborhood Hits	946	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.061105 (rank : 454)
Query Neighborhood Hits	438	Target Neighborhood Hits	964	Shared Neighborhood Hits	107
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SRRM1_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.087247 (rank : 296)
Query Neighborhood Hits	438	Target Neighborhood Hits	690	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.099670 (rank : 248)
Query Neighborhood Hits	438	Target Neighborhood Hits	966	Shared Neighborhood Hits	156
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.060396 (rank : 458)
Query Neighborhood Hits	438	Target Neighborhood Hits	1296	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.071147 (rank : 372)
Query Neighborhood Hits	438	Target Neighborhood Hits	1470	Shared Neighborhood Hits	172
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SSBP4_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.071084 (rank : 375)
Query Neighborhood Hits	438	Target Neighborhood Hits	753	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STAC3_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.248866 (rank : 103)
Query Neighborhood Hits	438	Target Neighborhood Hits	228	Shared Neighborhood Hits	138
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.249744 (rank : 101)
Query Neighborhood Hits	438	Target Neighborhood Hits	232	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STS1_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.078415 (rank : 338)
Query Neighborhood Hits	438	Target Neighborhood Hits	106	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS1_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.078157 (rank : 341)
Query Neighborhood Hits	438	Target Neighborhood Hits	104	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS2_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.099865 (rank : 247)
Query Neighborhood Hits	438	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SYP2L_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.053654 (rank : 535)
Query Neighborhood Hits	438	Target Neighborhood Hits	400	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

T22D4_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.052211 (rank : 554)
Query Neighborhood Hits	438	Target Neighborhood Hits	403	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TAB3_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.069712 (rank : 386)
Query Neighborhood Hits	438	Target Neighborhood Hits	168	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TARA_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.059670 (rank : 466)
Query Neighborhood Hits	438	Target Neighborhood Hits	1626	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.110071 (rank : 219)
Query Neighborhood Hits	438	Target Neighborhood Hits	768	Shared Neighborhood Hits	163
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TEC_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.067254 (rank : 404)
Query Neighborhood Hits	438	Target Neighborhood Hits	1006	Shared Neighborhood Hits	137
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.066069 (rank : 412)
Query Neighborhood Hits	438	Target Neighborhood Hits	1006	Shared Neighborhood Hits	136
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TENS4_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.051899 (rank : 558)
Query Neighborhood Hits	438	Target Neighborhood Hits	225	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

TIAM1_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.085309 (rank : 304)
Query Neighborhood Hits	438	Target Neighborhood Hits	225	Shared Neighborhood Hits	35
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.084667 (rank : 310)
Query Neighborhood Hits	438	Target Neighborhood Hits	205	Shared Neighborhood Hits	29
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TM108_MOUSE
θ value	θ > 10 (rank : 669)	NC score	0.052094 (rank : 556)
Query Neighborhood Hits	438	Target Neighborhood Hits	336	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TROAP_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.067348 (rank : 403)
Query Neighborhood Hits	438	Target Neighborhood Hits	258	Shared Neighborhood Hits	67
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

WASP_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.069907 (rank : 385)
Query Neighborhood Hits	438	Target Neighborhood Hits	195	Shared Neighborhood Hits	54
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.070937 (rank : 377)
Query Neighborhood Hits	438	Target Neighborhood Hits	223	Shared Neighborhood Hits	50
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.088716 (rank : 293)
Query Neighborhood Hits	438	Target Neighborhood Hits	354	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.081250 (rank : 321)
Query Neighborhood Hits	438	Target Neighborhood Hits	362	Shared Neighborhood Hits	73
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBP2_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.050538 (rank : 569)
Query Neighborhood Hits	438	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	P97765	Gene names	Wbp2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

YLPM1_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.103957 (rank : 229)
Query Neighborhood Hits	438	Target Neighborhood Hits	505	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZIMP7_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.071089 (rank : 374)
Query Neighborhood Hits	438	Target Neighborhood Hits	566	Shared Neighborhood Hits	129
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN207_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.065678 (rank : 419)
Query Neighborhood Hits	438	Target Neighborhood Hits	326	Shared Neighborhood Hits	47
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

BCAR1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	438	Target Neighborhood Hits	438	Shared Neighborhood Hits	438
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_HUMAN
NC score	0.956575 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	438	Target Neighborhood Hits	554	Shared Neighborhood Hits	362
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CASL_MOUSE
NC score	0.896636 (rank : 3)	θ value	9.87422e-140 (rank : 3)
Query Neighborhood Hits	438	Target Neighborhood Hits	225	Shared Neighborhood Hits	158
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CASL_HUMAN
NC score	0.890661 (rank : 4)	θ value	5.07123e-136 (rank : 4)
Query Neighborhood Hits	438	Target Neighborhood Hits	259	Shared Neighborhood Hits	165
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CT032_HUMAN
NC score	0.801408 (rank : 5)	θ value	6.15952e-41 (rank : 5)
Query Neighborhood Hits	438	Target Neighborhood Hits	235	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

EFS_HUMAN
NC score	0.740616 (rank : 6)	θ value	2.59387e-31 (rank : 6)
Query Neighborhood Hits	438	Target Neighborhood Hits	348	Shared Neighborhood Hits	196
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
NC score	0.732342 (rank : 7)	θ value	2.68423e-28 (rank : 7)
Query Neighborhood Hits	438	Target Neighborhood Hits	389	Shared Neighborhood Hits	213
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

CD2AP_MOUSE
NC score	0.493287 (rank : 8)	θ value	1.69304e-06 (rank : 13)
Query Neighborhood Hits	438	Target Neighborhood Hits	336	Shared Neighborhood Hits	185
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2AP_HUMAN
NC score	0.476777 (rank : 9)	θ value	3.19293e-05 (rank : 18)
Query Neighborhood Hits	438	Target Neighborhood Hits	315	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

SH3K1_MOUSE
NC score	0.476374 (rank : 10)	θ value	9.92553e-07 (rank : 11)
Query Neighborhood Hits	438	Target Neighborhood Hits	332	Shared Neighborhood Hits	174
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SH3K1_HUMAN
NC score	0.473198 (rank : 11)	θ value	4.92598e-06 (rank : 16)
Query Neighborhood Hits	438	Target Neighborhood Hits	341	Shared Neighborhood Hits	170
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

HCLS1_HUMAN
NC score	0.463584 (rank : 12)	θ value	7.1131e-05 (rank : 23)
Query Neighborhood Hits	438	Target Neighborhood Hits	358	Shared Neighborhood Hits	201
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

PPIP1_HUMAN
NC score	0.446344 (rank : 13)	θ value	4.45536e-07 (rank : 10)
Query Neighborhood Hits	438	Target Neighborhood Hits	389	Shared Neighborhood Hits	174
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

HCLS1_MOUSE
NC score	0.442069 (rank : 14)	θ value	0.000461057 (rank : 42)
Query Neighborhood Hits	438	Target Neighborhood Hits	329	Shared Neighborhood Hits	191
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

PPIP1_MOUSE
NC score	0.442027 (rank : 15)	θ value	2.88788e-06 (rank : 14)
Query Neighborhood Hits	438	Target Neighborhood Hits	377	Shared Neighborhood Hits	169
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PEX13_MOUSE
NC score	0.434689 (rank : 16)	θ value	1.09739e-05 (rank : 17)
Query Neighborhood Hits	438	Target Neighborhood Hits	126	Shared Neighborhood Hits	105
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_HUMAN
NC score	0.433092 (rank : 17)	θ value	3.19293e-05 (rank : 21)
Query Neighborhood Hits	438	Target Neighborhood Hits	128	Shared Neighborhood Hits	107
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

NCF2_HUMAN
NC score	0.407357 (rank : 18)	θ value	0.163984 (rank : 146)
Query Neighborhood Hits	438	Target Neighborhood Hits	229	Shared Neighborhood Hits	145
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

SRC8_MOUSE
NC score	0.406028 (rank : 19)	θ value	0.00102713 (rank : 46)
Query Neighborhood Hits	438	Target Neighborhood Hits	292	Shared Neighborhood Hits	165
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRC8_HUMAN
NC score	0.405353 (rank : 20)	θ value	0.00134147 (rank : 48)
Query Neighborhood Hits	438	Target Neighborhood Hits	269	Shared Neighborhood Hits	163
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

VINEX_MOUSE
NC score	0.404914 (rank : 21)	θ value	0.00509761 (rank : 68)
Query Neighborhood Hits	438	Target Neighborhood Hits	286	Shared Neighborhood Hits	169
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SH3G2_MOUSE
NC score	0.401984 (rank : 22)	θ value	0.000786445 (rank : 44)
Query Neighborhood Hits	438	Target Neighborhood Hits	319	Shared Neighborhood Hits	161
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

ABI2_HUMAN
NC score	0.400013 (rank : 23)	θ value	0.00298849 (rank : 57)
Query Neighborhood Hits	438	Target Neighborhood Hits	350	Shared Neighborhood Hits	184
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

VINEX_HUMAN
NC score	0.398711 (rank : 24)	θ value	0.0113563 (rank : 84)
Query Neighborhood Hits	438	Target Neighborhood Hits	270	Shared Neighborhood Hits	163
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

SH3G2_HUMAN
NC score	0.393636 (rank : 25)	θ value	0.00134147 (rank : 47)
Query Neighborhood Hits	438	Target Neighborhood Hits	324	Shared Neighborhood Hits	158
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

ABI2_MOUSE
NC score	0.391987 (rank : 26)	θ value	0.00298849 (rank : 58)
Query Neighborhood Hits	438	Target Neighborhood Hits	266	Shared Neighborhood Hits	163
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

GRAP2_MOUSE
NC score	0.388502 (rank : 27)	θ value	0.000461057 (rank : 39)
Query Neighborhood Hits	438	Target Neighborhood Hits	297	Shared Neighborhood Hits	175
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRB2_HUMAN
NC score	0.383277 (rank : 28)	θ value	0.000461057 (rank : 40)
Query Neighborhood Hits	438	Target Neighborhood Hits	310	Shared Neighborhood Hits	172
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

NCK1_HUMAN
NC score	0.383095 (rank : 29)	θ value	0.00020696 (rank : 33)
Query Neighborhood Hits	438	Target Neighborhood Hits	312	Shared Neighborhood Hits	170
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

GRB2_MOUSE
NC score	0.382990 (rank : 30)	θ value	0.000461057 (rank : 41)
Query Neighborhood Hits	438	Target Neighborhood Hits	312	Shared Neighborhood Hits	172
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

SH3G1_MOUSE
NC score	0.381752 (rank : 31)	θ value	0.00298849 (rank : 60)
Query Neighborhood Hits	438	Target Neighborhood Hits	291	Shared Neighborhood Hits	160
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

NCF1_HUMAN
NC score	0.379250 (rank : 32)	θ value	0.0563607 (rank : 107)
Query Neighborhood Hits	438	Target Neighborhood Hits	198	Shared Neighborhood Hits	144
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

SH3G3_HUMAN
NC score	0.377026 (rank : 33)	θ value	0.0252991 (rank : 96)
Query Neighborhood Hits	438	Target Neighborhood Hits	222	Shared Neighborhood Hits	153
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

GRAP2_HUMAN
NC score	0.376888 (rank : 34)	θ value	0.00175202 (rank : 51)
Query Neighborhood Hits	438	Target Neighborhood Hits	304	Shared Neighborhood Hits	176
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

SRBS1_MOUSE
NC score	0.375925 (rank : 35)	θ value	0.0252991 (rank : 97)
Query Neighborhood Hits	438	Target Neighborhood Hits	409	Shared Neighborhood Hits	183
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SH3G3_MOUSE
NC score	0.371292 (rank : 36)	θ value	0.125558 (rank : 141)
Query Neighborhood Hits	438	Target Neighborhood Hits	236	Shared Neighborhood Hits	157
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

NCK2_HUMAN
NC score	0.368834 (rank : 37)	θ value	0.00390308 (rank : 63)
Query Neighborhood Hits	438	Target Neighborhood Hits	310	Shared Neighborhood Hits	172
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

SRBS1_HUMAN
NC score	0.368247 (rank : 38)	θ value	0.0736092 (rank : 119)
Query Neighborhood Hits	438	Target Neighborhood Hits	396	Shared Neighborhood Hits	176
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

IASPP_HUMAN
NC score	0.367494 (rank : 39)	θ value	1.99992e-07 (rank : 9)
Query Neighborhood Hits	438	Target Neighborhood Hits	688	Shared Neighborhood Hits	214
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

GRAP_MOUSE
NC score	0.367445 (rank : 40)	θ value	0.00509761 (rank : 67)
Query Neighborhood Hits	438	Target Neighborhood Hits	309	Shared Neighborhood Hits	174
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

NCF1_MOUSE
NC score	0.367341 (rank : 41)	θ value	0.0736092 (rank : 116)
Query Neighborhood Hits	438	Target Neighborhood Hits	198	Shared Neighborhood Hits	149
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

ARHG7_HUMAN
NC score	0.363842 (rank : 42)	θ value	0.000270298 (rank : 35)
Query Neighborhood Hits	438	Target Neighborhood Hits	347	Shared Neighborhood Hits	170
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

IASPP_MOUSE
NC score	0.361344 (rank : 43)	θ value	5.26297e-08 (rank : 8)
Query Neighborhood Hits	438	Target Neighborhood Hits	1024	Shared Neighborhood Hits	276
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

GRAP_HUMAN
NC score	0.360738 (rank : 44)	θ value	0.00390308 (rank : 62)
Query Neighborhood Hits	438	Target Neighborhood Hits	307	Shared Neighborhood Hits	178
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

DNMBP_HUMAN
NC score	0.360709 (rank : 45)	θ value	0.00298849 (rank : 59)
Query Neighborhood Hits	438	Target Neighborhood Hits	413	Shared Neighborhood Hits	176
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ABI1_MOUSE
NC score	0.359118 (rank : 46)	θ value	0.0431538 (rank : 102)
Query Neighborhood Hits	438	Target Neighborhood Hits	246	Shared Neighborhood Hits	162
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

NCF4_MOUSE
NC score	0.357361 (rank : 47)	θ value	0.0961366 (rank : 125)
Query Neighborhood Hits	438	Target Neighborhood Hits	177	Shared Neighborhood Hits	135
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ARHG7_MOUSE
NC score	0.355381 (rank : 48)	θ value	0.00175202 (rank : 49)
Query Neighborhood Hits	438	Target Neighborhood Hits	396	Shared Neighborhood Hits	165
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

SH3G1_HUMAN
NC score	0.354960 (rank : 49)	θ value	0.0961366 (rank : 134)
Query Neighborhood Hits	438	Target Neighborhood Hits	307	Shared Neighborhood Hits	157
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

DNMBP_MOUSE
NC score	0.350355 (rank : 50)	θ value	0.00665767 (rank : 70)
Query Neighborhood Hits	438	Target Neighborhood Hits	435	Shared Neighborhood Hits	188
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ABI1_HUMAN
NC score	0.346882 (rank : 51)	θ value	0.0736092 (rank : 111)
Query Neighborhood Hits	438	Target Neighborhood Hits	257	Shared Neighborhood Hits	168
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

STAC_HUMAN
NC score	0.346658 (rank : 52)	θ value	0.125558 (rank : 142)
Query Neighborhood Hits	438	Target Neighborhood Hits	276	Shared Neighborhood Hits	156
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CRKL_HUMAN
NC score	0.345675 (rank : 53)	θ value	0.00509761 (rank : 66)
Query Neighborhood Hits	438	Target Neighborhood Hits	313	Shared Neighborhood Hits	169
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

STAM1_HUMAN
NC score	0.341245 (rank : 54)	θ value	0.0736092 (rank : 120)
Query Neighborhood Hits	438	Target Neighborhood Hits	271	Shared Neighborhood Hits	174
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
NC score	0.341240 (rank : 55)	θ value	0.0736092 (rank : 121)
Query Neighborhood Hits	438	Target Neighborhood Hits	273	Shared Neighborhood Hits	178
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
NC score	0.339911 (rank : 56)	θ value	0.0961366 (rank : 136)
Query Neighborhood Hits	438	Target Neighborhood Hits	285	Shared Neighborhood Hits	174
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

PACN2_HUMAN
NC score	0.338247 (rank : 57)	θ value	0.0563607 (rank : 108)
Query Neighborhood Hits	438	Target Neighborhood Hits	339	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
NC score	0.334867 (rank : 58)	θ value	0.0961366 (rank : 128)
Query Neighborhood Hits	438	Target Neighborhood Hits	382	Shared Neighborhood Hits	168
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN1_MOUSE
NC score	0.330720 (rank : 59)	θ value	0.163984 (rank : 148)
Query Neighborhood Hits	438	Target Neighborhood Hits	283	Shared Neighborhood Hits	158
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

STAC_MOUSE
NC score	0.330587 (rank : 60)	θ value	0.365318 (rank : 187)
Query Neighborhood Hits	438	Target Neighborhood Hits	268	Shared Neighborhood Hits	153
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

NPHP1_MOUSE
NC score	0.330167 (rank : 61)	θ value	0.00665767 (rank : 73)
Query Neighborhood Hits	438	Target Neighborhood Hits	267	Shared Neighborhood Hits	150
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

CRK_MOUSE
NC score	0.329808 (rank : 62)	θ value	0.0563607 (rank : 106)
Query Neighborhood Hits	438	Target Neighborhood Hits	314	Shared Neighborhood Hits	173
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

PACN1_HUMAN
NC score	0.328708 (rank : 63)	θ value	0.163984 (rank : 147)
Query Neighborhood Hits	438	Target Neighborhood Hits	320	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

NCF4_HUMAN
NC score	0.327024 (rank : 64)	θ value	0.62314 (rank : 214)
Query Neighborhood Hits	438	Target Neighborhood Hits	161	Shared Neighborhood Hits	122
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ARHG6_MOUSE
NC score	0.325989 (rank : 65)	θ value	0.0736092 (rank : 113)
Query Neighborhood Hits	438	Target Neighborhood Hits	394	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

CRKL_MOUSE
NC score	0.325136 (rank : 66)	θ value	0.0148317 (rank : 85)
Query Neighborhood Hits	438	Target Neighborhood Hits	307	Shared Neighborhood Hits	163
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

PACN3_MOUSE
NC score	0.320160 (rank : 67)	θ value	0.0961366 (rank : 130)
Query Neighborhood Hits	438	Target Neighborhood Hits	380	Shared Neighborhood Hits	153
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

ARHG6_HUMAN
NC score	0.319672 (rank : 68)	θ value	0.0736092 (rank : 112)
Query Neighborhood Hits	438	Target Neighborhood Hits	376	Shared Neighborhood Hits	160
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

VAV_HUMAN
NC score	0.317178 (rank : 69)	θ value	0.000158464 (rank : 31)
Query Neighborhood Hits	438	Target Neighborhood Hits	452	Shared Neighborhood Hits	166
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

PACN3_HUMAN
NC score	0.316780 (rank : 70)	θ value	0.0961366 (rank : 129)
Query Neighborhood Hits	438	Target Neighborhood Hits	385	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

STAM2_HUMAN
NC score	0.315923 (rank : 71)	θ value	0.47712 (rank : 202)
Query Neighborhood Hits	438	Target Neighborhood Hits	288	Shared Neighborhood Hits	174
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

VAV_MOUSE
NC score	0.315826 (rank : 72)	θ value	0.00020696 (rank : 34)
Query Neighborhood Hits	438	Target Neighborhood Hits	430	Shared Neighborhood Hits	166
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ASPP1_MOUSE
NC score	0.315472 (rank : 73)	θ value	3.77169e-06 (rank : 15)
Query Neighborhood Hits	438	Target Neighborhood Hits	1244	Shared Neighborhood Hits	268
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CRK_HUMAN
NC score	0.308299 (rank : 74)	θ value	3.0926 (rank : 317)
Query Neighborhood Hits	438	Target Neighborhood Hits	308	Shared Neighborhood Hits	169
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

ASPP1_HUMAN
NC score	0.307043 (rank : 75)	θ value	1.29631e-06 (rank : 12)
Query Neighborhood Hits	438	Target Neighborhood Hits	956	Shared Neighborhood Hits	195
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RUSC1_HUMAN
NC score	0.305968 (rank : 76)	θ value	0.00390308 (rank : 64)
Query Neighborhood Hits	438	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

OSTF1_HUMAN
NC score	0.305856 (rank : 77)	θ value	0.0148317 (rank : 87)
Query Neighborhood Hits	438	Target Neighborhood Hits	466	Shared Neighborhood Hits	169
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
NC score	0.304737 (rank : 78)	θ value	0.0113563 (rank : 83)
Query Neighborhood Hits	438	Target Neighborhood Hits	467	Shared Neighborhood Hits	170
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

NPHP1_HUMAN
NC score	0.300611 (rank : 79)	θ value	0.0193708 (rank : 93)
Query Neighborhood Hits	438	Target Neighborhood Hits	288	Shared Neighborhood Hits	140
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

AHI1_HUMAN
NC score	0.299402 (rank : 80)	θ value	0.00102713 (rank : 45)
Query Neighborhood Hits	438	Target Neighborhood Hits	537	Shared Neighborhood Hits	168
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ITSN2_HUMAN
NC score	0.289381 (rank : 81)	θ value	0.000158464 (rank : 30)
Query Neighborhood Hits	438	Target Neighborhood Hits	1173	Shared Neighborhood Hits	191
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

AHI1_MOUSE
NC score	0.287388 (rank : 82)	θ value	0.00665767 (rank : 69)
Query Neighborhood Hits	438	Target Neighborhood Hits	496	Shared Neighborhood Hits	166
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ITSN1_MOUSE
NC score	0.283942 (rank : 83)	θ value	5.44631e-05 (rank : 22)
Query Neighborhood Hits	438	Target Neighborhood Hits	1669	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.281465 (rank : 84)	θ value	0.00020696 (rank : 32)
Query Neighborhood Hits	438	Target Neighborhood Hits	1757	Shared Neighborhood Hits	242
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NOXO1_MOUSE
NC score	0.277479 (rank : 85)	θ value	0.0961366 (rank : 127)
Query Neighborhood Hits	438	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

ITSN2_MOUSE
NC score	0.273268 (rank : 86)	θ value	7.1131e-05 (rank : 24)
Query Neighborhood Hits	438	Target Neighborhood Hits	1371	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RUSC1_MOUSE
NC score	0.271994 (rank : 87)	θ value	0.0431538 (rank : 104)
Query Neighborhood Hits	438	Target Neighborhood Hits	206	Shared Neighborhood Hits	128
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

ARHG9_HUMAN
NC score	0.269736 (rank : 88)	θ value	0.00390308 (rank : 61)
Query Neighborhood Hits	438	Target Neighborhood Hits	235	Shared Neighborhood Hits	144
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
NC score	0.267334 (rank : 89)	θ value	0.00869519 (rank : 75)
Query Neighborhood Hits	438	Target Neighborhood Hits	234	Shared Neighborhood Hits	144
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

NEBL_HUMAN
NC score	0.264514 (rank : 90)	θ value	0.0961366 (rank : 126)
Query Neighborhood Hits	438	Target Neighborhood Hits	457	Shared Neighborhood Hits	147
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

ABI3_HUMAN
NC score	0.264449 (rank : 91)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	159
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

LASP1_HUMAN
NC score	0.263020 (rank : 92)	θ value	3.0926 (rank : 320)
Query Neighborhood Hits	438	Target Neighborhood Hits	293	Shared Neighborhood Hits	146
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ABI3_MOUSE
NC score	0.262897 (rank : 93)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

LASP1_MOUSE
NC score	0.260295 (rank : 94)	θ value	3.0926 (rank : 321)
Query Neighborhood Hits	438	Target Neighborhood Hits	297	Shared Neighborhood Hits	144
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

VAV2_HUMAN
NC score	0.259754 (rank : 95)	θ value	0.365318 (rank : 188)
Query Neighborhood Hits	438	Target Neighborhood Hits	453	Shared Neighborhood Hits	167
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
NC score	0.259679 (rank : 96)	θ value	0.365318 (rank : 189)
Query Neighborhood Hits	438	Target Neighborhood Hits	456	Shared Neighborhood Hits	169
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

DBNL_MOUSE
NC score	0.258906 (rank : 97)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	438	Target Neighborhood Hits	306	Shared Neighborhood Hits	147
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DBNL_HUMAN
NC score	0.258826 (rank : 98)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	438	Target Neighborhood Hits	244	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

ASPP2_HUMAN
NC score	0.251803 (rank : 99)	θ value	9.29e-05 (rank : 26)
Query Neighborhood Hits	438	Target Neighborhood Hits	1156	Shared Neighborhood Hits	207
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ARHG4_HUMAN
NC score	0.250544 (rank : 100)	θ value	0.47712 (rank : 191)
Query Neighborhood Hits	438	Target Neighborhood Hits	242	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

STAC3_MOUSE
NC score	0.249744 (rank : 101)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	438	Target Neighborhood Hits	232	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

VAV3_HUMAN
NC score	0.249350 (rank : 102)	θ value	0.279714 (rank : 172)
Query Neighborhood Hits	438	Target Neighborhood Hits	398	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

STAC3_HUMAN
NC score	0.248866 (rank : 103)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	438	Target Neighborhood Hits	228	Shared Neighborhood Hits	138
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

SNX18_MOUSE
NC score	0.248389 (rank : 104)	θ value	0.365318 (rank : 185)
Query Neighborhood Hits	438	Target Neighborhood Hits	198	Shared Neighborhood Hits	121
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

VAV3_MOUSE
NC score	0.242992 (rank : 105)	θ value	0.47712 (rank : 206)
Query Neighborhood Hits	438	Target Neighborhood Hits	404	Shared Neighborhood Hits	166
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

RHG04_HUMAN
NC score	0.238912 (rank : 106)	θ value	0.0431538 (rank : 103)
Query Neighborhood Hits	438	Target Neighborhood Hits	307	Shared Neighborhood Hits	155
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SNX18_HUMAN
NC score	0.237632 (rank : 107)	θ value	0.62314 (rank : 217)
Query Neighborhood Hits	438	Target Neighborhood Hits	207	Shared Neighborhood Hits	125
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

NEBU_HUMAN
NC score	0.230376 (rank : 108)	θ value	0.365318 (rank : 182)
Query Neighborhood Hits	438	Target Neighborhood Hits	420	Shared Neighborhood Hits	150
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

TCGAP_HUMAN
NC score	0.225368 (rank : 109)	θ value	0.00035302 (rank : 38)
Query Neighborhood Hits	438	Target Neighborhood Hits	872	Shared Neighborhood Hits	251
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RIMB2_HUMAN
NC score	0.224687 (rank : 110)	θ value	0.62314 (rank : 216)
Query Neighborhood Hits	438	Target Neighborhood Hits	263	Shared Neighborhood Hits	116
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ES8L3_MOUSE
NC score	0.221751 (rank : 111)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	438	Target Neighborhood Hits	168	Shared Neighborhood Hits	127
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

RIMB2_MOUSE
NC score	0.215348 (rank : 112)	θ value	1.06291 (rank : 246)
Query Neighborhood Hits	438	Target Neighborhood Hits	246	Shared Neighborhood Hits	103
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

PLCG1_MOUSE
NC score	0.212935 (rank : 113)	θ value	2.36792 (rank : 301)
Query Neighborhood Hits	438	Target Neighborhood Hits	314	Shared Neighborhood Hits	147
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

NOXO1_HUMAN
NC score	0.210448 (rank : 114)	θ value	1.06291 (rank : 242)
Query Neighborhood Hits	438	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

PLCG1_HUMAN
NC score	0.204680 (rank : 115)	θ value	2.36792 (rank : 300)
Query Neighborhood Hits	438	Target Neighborhood Hits	293	Shared Neighborhood Hits	142
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

ES8L2_HUMAN
NC score	0.204093 (rank : 116)	θ value	0.0736092 (rank : 114)
Query Neighborhood Hits	438	Target Neighborhood Hits	193	Shared Neighborhood Hits	132
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

EPS8_MOUSE
NC score	0.203863 (rank : 117)	θ value	0.00665767 (rank : 71)
Query Neighborhood Hits	438	Target Neighborhood Hits	157	Shared Neighborhood Hits	113
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

PLCG2_HUMAN
NC score	0.203401 (rank : 118)	θ value	1.06291 (rank : 243)
Query Neighborhood Hits	438	Target Neighborhood Hits	280	Shared Neighborhood Hits	143
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

TCGAP_MOUSE
NC score	0.200804 (rank : 119)	θ value	0.00175202 (rank : 53)
Query Neighborhood Hits	438	Target Neighborhood Hits	409	Shared Neighborhood Hits	151
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MYO1F_HUMAN
NC score	0.198820 (rank : 120)	θ value	3.19293e-05 (rank : 19)
Query Neighborhood Hits	438	Target Neighborhood Hits	275	Shared Neighborhood Hits	167
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
NC score	0.197942 (rank : 121)	θ value	3.19293e-05 (rank : 20)
Query Neighborhood Hits	438	Target Neighborhood Hits	262	Shared Neighborhood Hits	161
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

EPS8_HUMAN
NC score	0.197529 (rank : 122)	θ value	0.0113563 (rank : 82)
Query Neighborhood Hits	438	Target Neighborhood Hits	151	Shared Neighborhood Hits	105
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ES8L2_MOUSE
NC score	0.190894 (rank : 123)	θ value	0.365318 (rank : 177)
Query Neighborhood Hits	438	Target Neighborhood Hits	169	Shared Neighborhood Hits	119
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

SPTA2_HUMAN
NC score	0.189695 (rank : 124)	θ value	0.000270298 (rank : 36)
Query Neighborhood Hits	438	Target Neighborhood Hits	888	Shared Neighborhood Hits	166
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRGP2_MOUSE
NC score	0.189327 (rank : 125)	θ value	0.163984 (rank : 154)
Query Neighborhood Hits	438	Target Neighborhood Hits	324	Shared Neighborhood Hits	145
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

DDEF2_MOUSE
NC score	0.188964 (rank : 126)	θ value	0.00869519 (rank : 77)
Query Neighborhood Hits	438	Target Neighborhood Hits	625	Shared Neighborhood Hits	169
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF1_MOUSE
NC score	0.187140 (rank : 127)	θ value	0.125558 (rank : 138)
Query Neighborhood Hits	438	Target Neighborhood Hits	592	Shared Neighborhood Hits	174
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

RHG26_HUMAN
NC score	0.185702 (rank : 128)	θ value	0.21417 (rank : 163)
Query Neighborhood Hits	438	Target Neighborhood Hits	281	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

ARHG4_MOUSE
NC score	0.184757 (rank : 129)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	438	Target Neighborhood Hits	185	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

MYO1E_HUMAN
NC score	0.183846 (rank : 130)	θ value	0.00035302 (rank : 37)
Query Neighborhood Hits	438	Target Neighborhood Hits	293	Shared Neighborhood Hits	167
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

SRGP2_HUMAN
NC score	0.183635 (rank : 131)	θ value	0.365318 (rank : 186)
Query Neighborhood Hits	438	Target Neighborhood Hits	331	Shared Neighborhood Hits	143
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

DDEF2_HUMAN
NC score	0.183006 (rank : 132)	θ value	0.00869519 (rank : 76)
Query Neighborhood Hits	438	Target Neighborhood Hits	599	Shared Neighborhood Hits	168
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ES8L3_HUMAN
NC score	0.176485 (rank : 133)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	438	Target Neighborhood Hits	206	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

SRGP1_HUMAN
NC score	0.174004 (rank : 134)	θ value	2.36792 (rank : 306)
Query Neighborhood Hits	438	Target Neighborhood Hits	390	Shared Neighborhood Hits	143
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

ANM2_HUMAN
NC score	0.171167 (rank : 135)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	438	Target Neighborhood Hits	175	Shared Neighborhood Hits	140
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

FNBP2_HUMAN
NC score	0.169189 (rank : 136)	θ value	1.38821 (rank : 264)
Query Neighborhood Hits	438	Target Neighborhood Hits	432	Shared Neighborhood Hits	156
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

SPTA1_HUMAN
NC score	0.168518 (rank : 137)	θ value	0.00390308 (rank : 65)
Query Neighborhood Hits	438	Target Neighborhood Hits	748	Shared Neighborhood Hits	162
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

PRP2_MOUSE
NC score	0.168282 (rank : 138)	θ value	1.38821 (rank : 273)
Query Neighborhood Hits	438	Target Neighborhood Hits	347	Shared Neighborhood Hits	86
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

ANM2_MOUSE
NC score	0.164529 (rank : 139)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	438	Target Neighborhood Hits	175	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

WASIP_MOUSE
NC score	0.161292 (rank : 140)	θ value	1.06291 (rank : 254)
Query Neighborhood Hits	438	Target Neighborhood Hits	392	Shared Neighborhood Hits	102
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ATN1_HUMAN
NC score	0.159925 (rank : 141)	θ value	0.000786445 (rank : 43)
Query Neighborhood Hits	438	Target Neighborhood Hits	676	Shared Neighborhood Hits	112
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SPTA1_MOUSE
NC score	0.158674 (rank : 142)	θ value	0.163984 (rank : 153)
Query Neighborhood Hits	438	Target Neighborhood Hits	675	Shared Neighborhood Hits	152
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

WASIP_HUMAN
NC score	0.157752 (rank : 143)	θ value	0.813845 (rank : 230)
Query Neighborhood Hits	438	Target Neighborhood Hits	458	Shared Neighborhood Hits	102
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SHLB1_MOUSE
NC score	0.155939 (rank : 144)	θ value	3.0926 (rank : 327)
Query Neighborhood Hits	438	Target Neighborhood Hits	101	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

RUSC2_HUMAN
NC score	0.155121 (rank : 145)	θ value	0.163984 (rank : 149)
Query Neighborhood Hits	438	Target Neighborhood Hits	205	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SHLB1_HUMAN
NC score	0.150320 (rank : 146)	θ value	4.03905 (rank : 344)
Query Neighborhood Hits	438	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SPN90_HUMAN
NC score	0.148970 (rank : 147)	θ value	1.38821 (rank : 275)
Query Neighborhood Hits	438	Target Neighborhood Hits	157	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

GSCR1_HUMAN
NC score	0.148217 (rank : 148)	θ value	0.163984 (rank : 143)
Query Neighborhood Hits	438	Target Neighborhood Hits	674	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PRRT3_HUMAN
NC score	0.148079 (rank : 149)	θ value	0.21417 (rank : 162)
Query Neighborhood Hits	438	Target Neighborhood Hits	998	Shared Neighborhood Hits	192
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ES8L1_HUMAN
NC score	0.147798 (rank : 150)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	438	Target Neighborhood Hits	162	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

RIMB1_HUMAN
NC score	0.147735 (rank : 151)	θ value	0.813845 (rank : 224)
Query Neighborhood Hits	438	Target Neighborhood Hits	1479	Shared Neighborhood Hits	187
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RERE_MOUSE
NC score	0.146920 (rank : 152)	θ value	0.0961366 (rank : 132)
Query Neighborhood Hits	438	Target Neighborhood Hits	785	Shared Neighborhood Hits	130
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RGS3_MOUSE
NC score	0.146016 (rank : 153)	θ value	0.00175202 (rank : 52)
Query Neighborhood Hits	438	Target Neighborhood Hits	1621	Shared Neighborhood Hits	230
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ES8L1_MOUSE
NC score	0.144949 (rank : 154)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	438	Target Neighborhood Hits	143	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

RUSC2_MOUSE
NC score	0.140670 (rank : 155)	θ value	1.06291 (rank : 247)
Query Neighborhood Hits	438	Target Neighborhood Hits	305	Shared Neighborhood Hits	103
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RERE_HUMAN
NC score	0.139382 (rank : 156)	θ value	0.0961366 (rank : 131)
Query Neighborhood Hits	438	Target Neighborhood Hits	779	Shared Neighborhood Hits	129
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RAPH1_HUMAN
NC score	0.139300 (rank : 157)	θ value	0.0563607 (rank : 110)
Query Neighborhood Hits	438	Target Neighborhood Hits	593	Shared Neighborhood Hits	131
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

GAK5_HUMAN
NC score	0.138881 (rank : 158)	θ value	0.00175202 (rank : 50)
Query Neighborhood Hits	438	Target Neighborhood Hits	429	Shared Neighborhood Hits	124
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SNX9_HUMAN
NC score	0.138409 (rank : 159)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	438	Target Neighborhood Hits	148	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

GAK4_HUMAN
NC score	0.138217 (rank : 160)	θ value	0.00228821 (rank : 56)
Query Neighborhood Hits	438	Target Neighborhood Hits	415	Shared Neighborhood Hits	121
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.138075 (rank : 161)	θ value	0.00228821 (rank : 54)
Query Neighborhood Hits	438	Target Neighborhood Hits	409	Shared Neighborhood Hits	121
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.138010 (rank : 162)	θ value	0.00228821 (rank : 55)
Query Neighborhood Hits	438	Target Neighborhood Hits	406	Shared Neighborhood Hits	120
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SF3A2_MOUSE
NC score	0.136496 (rank : 163)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	438	Target Neighborhood Hits	247	Shared Neighborhood Hits	66
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SPT5H_HUMAN
NC score	0.136392 (rank : 164)	θ value	0.163984 (rank : 151)
Query Neighborhood Hits	438	Target Neighborhood Hits	436	Shared Neighborhood Hits	110
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

GAK6_HUMAN
NC score	0.136328 (rank : 165)	θ value	0.00665767 (rank : 72)
Query Neighborhood Hits	438	Target Neighborhood Hits	392	Shared Neighborhood Hits	119
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MLL3_HUMAN
NC score	0.136221 (rank : 166)	θ value	0.00869519 (rank : 79)
Query Neighborhood Hits	438	Target Neighborhood Hits	1644	Shared Neighborhood Hits	210
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SF3A2_HUMAN
NC score	0.135974 (rank : 167)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	438	Target Neighborhood Hits	263	Shared Neighborhood Hits	70
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SPT5H_MOUSE
NC score	0.135767 (rank : 168)	θ value	0.163984 (rank : 152)
Query Neighborhood Hits	438	Target Neighborhood Hits	437	Shared Neighborhood Hits	109
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

OGFR_HUMAN
NC score	0.135229 (rank : 169)	θ value	0.365318 (rank : 183)
Query Neighborhood Hits	438	Target Neighborhood Hits	1582	Shared Neighborhood Hits	221
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MUC1_HUMAN
NC score	0.134190 (rank : 170)	θ value	0.0193708 (rank : 92)
Query Neighborhood Hits	438	Target Neighborhood Hits	975	Shared Neighborhood Hits	176
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SHAN1_HUMAN
NC score	0.134154 (rank : 171)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	438	Target Neighborhood Hits	1041	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

GAK12_HUMAN
NC score	0.133761 (rank : 172)	θ value	0.0252991 (rank : 94)
Query Neighborhood Hits	438	Target Neighborhood Hits	374	Shared Neighborhood Hits	113
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SON_HUMAN
NC score	0.133682 (rank : 173)	θ value	0.0961366 (rank : 135)
Query Neighborhood Hits	438	Target Neighborhood Hits	1568	Shared Neighborhood Hits	215
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MBD6_HUMAN
NC score	0.133320 (rank : 174)	θ value	0.365318 (rank : 180)
Query Neighborhood Hits	438	Target Neighborhood Hits	349	Shared Neighborhood Hits	71
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

M3KL4_HUMAN
NC score	0.133002 (rank : 175)	θ value	9.29e-05 (rank : 27)
Query Neighborhood Hits	438	Target Neighborhood Hits	1087	Shared Neighborhood Hits	169
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

PRP1_HUMAN
NC score	0.132054 (rank : 176)	θ value	1.06291 (rank : 244)
Query Neighborhood Hits	438	Target Neighborhood Hits	385	Shared Neighborhood Hits	84
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

BAT2_HUMAN
NC score	0.131333 (rank : 177)	θ value	0.62314 (rank : 209)
Query Neighborhood Hits	438	Target Neighborhood Hits	931	Shared Neighborhood Hits	163
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RIMB1_MOUSE
NC score	0.131157 (rank : 178)	θ value	0.62314 (rank : 215)
Query Neighborhood Hits	438	Target Neighborhood Hits	1376	Shared Neighborhood Hits	192
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NCOA6_HUMAN
NC score	0.130903 (rank : 179)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	438	Target Neighborhood Hits	1202	Shared Neighborhood Hits	210
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PRB4S_HUMAN
NC score	0.130806 (rank : 180)	θ value	1.38821 (rank : 272)
Query Neighborhood Hits	438	Target Neighborhood Hits	330	Shared Neighborhood Hits	78
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

WASL_MOUSE
NC score	0.130231 (rank : 181)	θ value	0.163984 (rank : 155)
Query Neighborhood Hits	438	Target Neighborhood Hits	339	Shared Neighborhood Hits	78
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

NACAM_MOUSE
NC score	0.130043 (rank : 182)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	438	Target Neighborhood Hits	1866	Shared Neighborhood Hits	238
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ARI1A_HUMAN
NC score	0.129189 (rank : 183)	θ value	0.0193708 (rank : 88)
Query Neighborhood Hits	438	Target Neighborhood Hits	787	Shared Neighborhood Hits	149
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

PRR12_HUMAN
NC score	0.128693 (rank : 184)	θ value	3.0926 (rank : 324)
Query Neighborhood Hits	438	Target Neighborhood Hits	460	Shared Neighborhood Hits	101
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

M3K11_HUMAN
NC score	0.128531 (rank : 185)	θ value	0.000121331 (rank : 29)
Query Neighborhood Hits	438	Target Neighborhood Hits	1136	Shared Neighborhood Hits	198
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

GAK10_HUMAN
NC score	0.128091 (rank : 186)	θ value	0.0193708 (rank : 91)
Query Neighborhood Hits	438	Target Neighborhood Hits	289	Shared Neighborhood Hits	98
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SHAN2_MOUSE
NC score	0.126817 (rank : 187)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	438	Target Neighborhood Hits	446	Shared Neighborhood Hits	136
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

WASL_HUMAN
NC score	0.126758 (rank : 188)	θ value	0.21417 (rank : 167)
Query Neighborhood Hits	438	Target Neighborhood Hits	312	Shared Neighborhood Hits	78
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MCF2L_MOUSE
NC score	0.126546 (rank : 189)	θ value	0.21417 (rank : 160)
Query Neighborhood Hits	438	Target Neighborhood Hits	255	Shared Neighborhood Hits	52
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

SNX9_MOUSE
NC score	0.126515 (rank : 190)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	438	Target Neighborhood Hits	141	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

SPN90_MOUSE
NC score	0.125843 (rank : 191)	θ value	2.36792 (rank : 304)
Query Neighborhood Hits	438	Target Neighborhood Hits	157	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

FA47B_HUMAN
NC score	0.124255 (rank : 192)	θ value	0.0193708 (rank : 90)
Query Neighborhood Hits	438	Target Neighborhood Hits	431	Shared Neighborhood Hits	126
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

LCP2_HUMAN
NC score	0.122598 (rank : 193)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	438	Target Neighborhood Hits	531	Shared Neighborhood Hits	158
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MLL3_MOUSE
NC score	0.122254 (rank : 194)	θ value	0.0148317 (rank : 86)
Query Neighborhood Hits	438	Target Neighborhood Hits	1399	Shared Neighborhood Hits	185
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NCOA6_MOUSE
NC score	0.121293 (rank : 195)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	438	Target Neighborhood Hits	1076	Shared Neighborhood Hits	207
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TAF4_HUMAN
NC score	0.120803 (rank : 196)	θ value	6.88961 (rank : 409)
Query Neighborhood Hits	438	Target Neighborhood Hits	687	Shared Neighborhood Hits	115
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

BSN_MOUSE
NC score	0.119634 (rank : 197)	θ value	2.36792 (rank : 295)
Query Neighborhood Hits	438	Target Neighborhood Hits	2057	Shared Neighborhood Hits	227
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BCL9_HUMAN
NC score	0.119588 (rank : 198)	θ value	1.38821 (rank : 256)
Query Neighborhood Hits	438	Target Neighborhood Hits	1008	Shared Neighborhood Hits	189
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

SHLB2_MOUSE
NC score	0.119136 (rank : 199)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	438	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

M3K9_HUMAN
NC score	0.117988 (rank : 200)	θ value	7.1131e-05 (rank : 25)
Query Neighborhood Hits	438	Target Neighborhood Hits	1123	Shared Neighborhood Hits	185
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MLL2_HUMAN
NC score	0.117879 (rank : 201)	θ value	0.47712 (rank : 198)
Query Neighborhood Hits	438	Target Neighborhood Hits	1788	Shared Neighborhood Hits	188
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SHLB2_HUMAN
NC score	0.117751 (rank : 202)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	438	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

YLPM1_HUMAN
NC score	0.116050 (rank : 203)	θ value	0.47712 (rank : 207)
Query Neighborhood Hits	438	Target Neighborhood Hits	670	Shared Neighborhood Hits	130
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

MUC7_HUMAN
NC score	0.115490 (rank : 204)	θ value	0.47712 (rank : 199)
Query Neighborhood Hits	438	Target Neighborhood Hits	538	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

GAK1_HUMAN
NC score	0.115272 (rank : 205)	θ value	3.0926 (rank : 319)
Query Neighborhood Hits	438	Target Neighborhood Hits	268	Shared Neighborhood Hits	88
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CPSF6_MOUSE
NC score	0.114751 (rank : 206)	θ value	3.0926 (rank : 316)
Query Neighborhood Hits	438	Target Neighborhood Hits	356	Shared Neighborhood Hits	89
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

BAT2_MOUSE
NC score	0.114213 (rank : 207)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	438	Target Neighborhood Hits	947	Shared Neighborhood Hits	164
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CPSF6_HUMAN
NC score	0.113576 (rank : 208)	θ value	3.0926 (rank : 315)
Query Neighborhood Hits	438	Target Neighborhood Hits	359	Shared Neighborhood Hits	88
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

PCLO_HUMAN
NC score	0.112490 (rank : 209)	θ value	1.81305 (rank : 290)
Query Neighborhood Hits	438	Target Neighborhood Hits	2046	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

GAK7_HUMAN
NC score	0.112044 (rank : 210)	θ value	0.21417 (rank : 158)
Query Neighborhood Hits	438	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

MISS_MOUSE
NC score	0.111726 (rank : 211)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	438	Target Neighborhood Hits	444	Shared Neighborhood Hits	138
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NGEF_MOUSE
NC score	0.111162 (rank : 212)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	438	Target Neighborhood Hits	228	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

WIRE_HUMAN
NC score	0.110958 (rank : 213)	θ value	5.27518 (rank : 380)
Query Neighborhood Hits	438	Target Neighborhood Hits	329	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WASF2_MOUSE
NC score	0.110846 (rank : 214)	θ value	1.06291 (rank : 252)
Query Neighborhood Hits	438	Target Neighborhood Hits	315	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF2_HUMAN
NC score	0.110697 (rank : 215)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	438	Target Neighborhood Hits	280	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

PCLO_MOUSE
NC score	0.110501 (rank : 216)	θ value	0.47712 (rank : 201)
Query Neighborhood Hits	438	Target Neighborhood Hits	2275	Shared Neighborhood Hits	244
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RNC_HUMAN
NC score	0.110223 (rank : 217)	θ value	0.0961366 (rank : 133)
Query Neighborhood Hits	438	Target Neighborhood Hits	176	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

RGS3_HUMAN
NC score	0.110159 (rank : 218)	θ value	0.0330416 (rank : 101)
Query Neighborhood Hits	438	Target Neighborhood Hits	1375	Shared Neighborhood Hits	200
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TARSH_HUMAN
NC score	0.110071 (rank : 219)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	438	Target Neighborhood Hits	768	Shared Neighborhood Hits	163
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SFPQ_MOUSE
NC score	0.109833 (rank : 220)	θ value	0.0431538 (rank : 105)
Query Neighborhood Hits	438	Target Neighborhood Hits	958	Shared Neighborhood Hits	122
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

GAK8_HUMAN
NC score	0.109420 (rank : 221)	θ value	1.06291 (rank : 239)
Query Neighborhood Hits	438	Target Neighborhood Hits	145	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NGEF_HUMAN
NC score	0.106592 (rank : 222)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	438	Target Neighborhood Hits	166	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARI1B_HUMAN
NC score	0.105898 (rank : 223)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	438	Target Neighborhood Hits	567	Shared Neighborhood Hits	125
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CCNK_MOUSE
NC score	0.105289 (rank : 224)	θ value	0.0961366 (rank : 122)
Query Neighborhood Hits	438	Target Neighborhood Hits	350	Shared Neighborhood Hits	85
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

EP300_HUMAN
NC score	0.104880 (rank : 225)	θ value	0.365318 (rank : 176)
Query Neighborhood Hits	438	Target Neighborhood Hits	821	Shared Neighborhood Hits	156
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ARHG5_HUMAN
NC score	0.104855 (rank : 226)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	438	Target Neighborhood Hits	172	Shared Neighborhood Hits	77
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

WIRE_MOUSE
NC score	0.104605 (rank : 227)	θ value	3.0926 (rank : 331)
Query Neighborhood Hits	438	Target Neighborhood Hits	310	Shared Neighborhood Hits	82
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CBP_MOUSE
NC score	0.104558 (rank : 228)	θ value	6.88961 (rank : 384)
Query Neighborhood Hits	438	Target Neighborhood Hits	1051	Shared Neighborhood Hits	182
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

YLPM1_MOUSE
NC score	0.103957 (rank : 229)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	438	Target Neighborhood Hits	505	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

FYN_MOUSE
NC score	0.103554 (rank : 230)	θ value	1.38821 (rank : 266)
Query Neighborhood Hits	438	Target Neighborhood Hits	1073	Shared Neighborhood Hits	171
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

M3K10_HUMAN
NC score	0.103473 (rank : 231)	θ value	0.00869519 (rank : 78)
Query Neighborhood Hits	438	Target Neighborhood Hits	1071	Shared Neighborhood Hits	161
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

YES_MOUSE
NC score	0.103429 (rank : 232)	θ value	0.813845 (rank : 232)
Query Neighborhood Hits	438	Target Neighborhood Hits	1052	Shared Neighborhood Hits	166
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

MAGE1_HUMAN
NC score	0.103414 (rank : 233)	θ value	0.47712 (rank : 196)
Query Neighborhood Hits	438	Target Neighborhood Hits	1389	Shared Neighborhood Hits	201
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PHC2_HUMAN
NC score	0.103373 (rank : 234)	θ value	0.0563607 (rank : 109)
Query Neighborhood Hits	438	Target Neighborhood Hits	388	Shared Neighborhood Hits	118
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

SFPQ_HUMAN
NC score	0.102949 (rank : 235)	θ value	0.279714 (rank : 171)
Query Neighborhood Hits	438	Target Neighborhood Hits	986	Shared Neighborhood Hits	117
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

YES_HUMAN
NC score	0.102917 (rank : 236)	θ value	0.813845 (rank : 231)
Query Neighborhood Hits	438	Target Neighborhood Hits	1059	Shared Neighborhood Hits	167
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

WASF4_HUMAN
NC score	0.102904 (rank : 237)	θ value	3.0926 (rank : 330)
Query Neighborhood Hits	438	Target Neighborhood Hits	282	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

SRC_HUMAN
NC score	0.102766 (rank : 238)	θ value	0.813845 (rank : 228)
Query Neighborhood Hits	438	Target Neighborhood Hits	1058	Shared Neighborhood Hits	174
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SYN1_HUMAN
NC score	0.102487 (rank : 239)	θ value	0.47712 (rank : 203)
Query Neighborhood Hits	438	Target Neighborhood Hits	419	Shared Neighborhood Hits	95
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SLAP2_HUMAN
NC score	0.102418 (rank : 240)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	438	Target Neighborhood Hits	139	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

FGR_HUMAN
NC score	0.102323 (rank : 241)	θ value	0.62314 (rank : 211)
Query Neighborhood Hits	438	Target Neighborhood Hits	1067	Shared Neighborhood Hits	166
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FYN_HUMAN
NC score	0.101898 (rank : 242)	θ value	1.38821 (rank : 265)
Query Neighborhood Hits	438	Target Neighborhood Hits	1078	Shared Neighborhood Hits	171
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

AMPH_HUMAN
NC score	0.101503 (rank : 243)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	438	Target Neighborhood Hits	455	Shared Neighborhood Hits	121
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

GAK3_HUMAN
NC score	0.101376 (rank : 244)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	438	Target Neighborhood Hits	182	Shared Neighborhood Hits	53
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

WASF1_MOUSE
NC score	0.100502 (rank : 245)	θ value	0.279714 (rank : 173)
Query Neighborhood Hits	438	Target Neighborhood Hits	261	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

MNT_HUMAN
NC score	0.100333 (rank : 246)	θ value	1.38821 (rank : 268)
Query Neighborhood Hits	438	Target Neighborhood Hits	496	Shared Neighborhood Hits	107
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

STS2_HUMAN
NC score	0.099865 (rank : 247)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	438	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SRRM1_MOUSE
NC score	0.099670 (rank : 248)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	438	Target Neighborhood Hits	966	Shared Neighborhood Hits	156
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SLAP2_MOUSE
NC score	0.099479 (rank : 249)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	438	Target Neighborhood Hits	136	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

R3HD2_MOUSE
NC score	0.098515 (rank : 250)	θ value	1.38821 (rank : 274)
Query Neighborhood Hits	438	Target Neighborhood Hits	397	Shared Neighborhood Hits	107
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

FGR_MOUSE
NC score	0.098314 (rank : 251)	θ value	3.0926 (rank : 318)
Query Neighborhood Hits	438	Target Neighborhood Hits	1069	Shared Neighborhood Hits	168
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

HCK_HUMAN
NC score	0.097872 (rank : 252)	θ value	0.0736092 (rank : 115)
Query Neighborhood Hits	438	Target Neighborhood Hits	1035	Shared Neighborhood Hits	165
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

MDC1_HUMAN
NC score	0.097655 (rank : 253)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	438	Target Neighborhood Hits	1446	Shared Neighborhood Hits	180
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

BTK_HUMAN
NC score	0.097566 (rank : 254)	θ value	1.06291 (rank : 235)
Query Neighborhood Hits	438	Target Neighborhood Hits	1026	Shared Neighborhood Hits	167
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

CBP_HUMAN
NC score	0.097225 (rank : 255)	θ value	3.0926 (rank : 314)
Query Neighborhood Hits	438	Target Neighborhood Hits	941	Shared Neighborhood Hits	160
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

P85A_MOUSE
NC score	0.096437 (rank : 256)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	438	Target Neighborhood Hits	435	Shared Neighborhood Hits	104
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CN032_HUMAN
NC score	0.096344 (rank : 257)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	438	Target Neighborhood Hits	267	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

SPTA3_MOUSE
NC score	0.096337 (rank : 258)	θ value	1.38821 (rank : 276)
Query Neighborhood Hits	438	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

ENAH_MOUSE
NC score	0.096285 (rank : 259)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	438	Target Neighborhood Hits	919	Shared Neighborhood Hits	115
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PRB3_HUMAN
NC score	0.095725 (rank : 260)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	438	Target Neighborhood Hits	318	Shared Neighborhood Hits	66
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SC24C_HUMAN
NC score	0.095697 (rank : 261)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	438	Target Neighborhood Hits	662	Shared Neighborhood Hits	162
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

WASF1_HUMAN
NC score	0.095618 (rank : 262)	θ value	0.365318 (rank : 190)
Query Neighborhood Hits	438	Target Neighborhood Hits	260	Shared Neighborhood Hits	73
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

SYN1_MOUSE
NC score	0.095533 (rank : 263)	θ value	0.62314 (rank : 218)
Query Neighborhood Hits	438	Target Neighborhood Hits	363	Shared Neighborhood Hits	84
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CN032_MOUSE
NC score	0.095372 (rank : 264)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	438	Target Neighborhood Hits	233	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

K1802_MOUSE
NC score	0.095145 (rank : 265)	θ value	2.36792 (rank : 298)
Query Neighborhood Hits	438	Target Neighborhood Hits	1596	Shared Neighborhood Hits	196
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WASF3_HUMAN
NC score	0.095102 (rank : 266)	θ value	1.06291 (rank : 253)
Query Neighborhood Hits	438	Target Neighborhood Hits	204	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

S23IP_MOUSE
NC score	0.094175 (rank : 267)	θ value	0.365318 (rank : 184)
Query Neighborhood Hits	438	Target Neighborhood Hits	363	Shared Neighborhood Hits	103
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

BCL9_MOUSE
NC score	0.094014 (rank : 268)	θ value	3.0926 (rank : 310)
Query Neighborhood Hits	438	Target Neighborhood Hits	770	Shared Neighborhood Hits	152
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

GAK18_HUMAN
NC score	0.093742 (rank : 269)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	438	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MDC1_MOUSE
NC score	0.093490 (rank : 270)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	438	Target Neighborhood Hits	998	Shared Neighborhood Hits	164
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BRD4_HUMAN
NC score	0.093307 (rank : 271)	θ value	0.813845 (rank : 220)
Query Neighborhood Hits	438	Target Neighborhood Hits	851	Shared Neighborhood Hits	124
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

HCK_MOUSE
NC score	0.093145 (rank : 272)	θ value	0.47712 (rank : 193)
Query Neighborhood Hits	438	Target Neighborhood Hits	1029	Shared Neighborhood Hits	162
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

SF01_HUMAN
NC score	0.092953 (rank : 273)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	438	Target Neighborhood Hits	287	Shared Neighborhood Hits	74
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

BIN1_HUMAN
NC score	0.092866 (rank : 274)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	438	Target Neighborhood Hits	335	Shared Neighborhood Hits	103
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CIP4_HUMAN
NC score	0.092636 (rank : 275)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	438	Target Neighborhood Hits	374	Shared Neighborhood Hits	74
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

MKL1_MOUSE
NC score	0.092427 (rank : 276)	θ value	0.47712 (rank : 197)
Query Neighborhood Hits	438	Target Neighborhood Hits	667	Shared Neighborhood Hits	133
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

P85A_HUMAN
NC score	0.091956 (rank : 277)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	438	Target Neighborhood Hits	479	Shared Neighborhood Hits	100
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PKHG1_HUMAN
NC score	0.091363 (rank : 278)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	438	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

FA47A_HUMAN
NC score	0.091328 (rank : 279)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	438	Target Neighborhood Hits	451	Shared Neighborhood Hits	114
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

AMPH_MOUSE
NC score	0.090928 (rank : 280)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	438	Target Neighborhood Hits	291	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

BRD4_MOUSE
NC score	0.090634 (rank : 281)	θ value	3.0926 (rank : 312)
Query Neighborhood Hits	438	Target Neighborhood Hits	845	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CSKI1_MOUSE
NC score	0.090501 (rank : 282)	θ value	0.0961366 (rank : 124)
Query Neighborhood Hits	438	Target Neighborhood Hits	1031	Shared Neighborhood Hits	193
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TAB3_MOUSE
NC score	0.090452 (rank : 283)	θ value	0.21417 (rank : 166)
Query Neighborhood Hits	438	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

ARHGG_MOUSE
NC score	0.090429 (rank : 284)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	438	Target Neighborhood Hits	152	Shared Neighborhood Hits	56
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CSKI1_HUMAN
NC score	0.090141 (rank : 285)	θ value	0.0961366 (rank : 123)
Query Neighborhood Hits	438	Target Neighborhood Hits	997	Shared Neighborhood Hits	167
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

BTK_MOUSE
NC score	0.090020 (rank : 286)	θ value	3.0926 (rank : 313)
Query Neighborhood Hits	438	Target Neighborhood Hits	1017	Shared Neighborhood Hits	159
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

ATX2L_HUMAN
NC score	0.089831 (rank : 287)	θ value	5.27518 (rank : 355)
Query Neighborhood Hits	438	Target Neighborhood Hits	443	Shared Neighborhood Hits	103
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

SLAP1_HUMAN
NC score	0.089701 (rank : 288)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	438	Target Neighborhood Hits	113	Shared Neighborhood Hits	44
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

CK024_HUMAN
NC score	0.089435 (rank : 289)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	438	Target Neighborhood Hits	408	Shared Neighborhood Hits	116
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

ATX2L_MOUSE
NC score	0.089332 (rank : 290)	θ value	3.0926 (rank : 309)
Query Neighborhood Hits	438	Target Neighborhood Hits	401	Shared Neighborhood Hits	93
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

SRC_MOUSE
NC score	0.089246 (rank : 291)	θ value	2.36792 (rank : 305)
Query Neighborhood Hits	438	Target Neighborhood Hits	1033	Shared Neighborhood Hits	159
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SAPS1_HUMAN
NC score	0.089216 (rank : 292)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	438	Target Neighborhood Hits	704	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

WBP11_HUMAN
NC score	0.088716 (rank : 293)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	438	Target Neighborhood Hits	354	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

DOCK1_HUMAN
NC score	0.087689 (rank : 294)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	438	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

SLAP1_MOUSE
NC score	0.087529 (rank : 295)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	438	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SRRM1_HUMAN
NC score	0.087247 (rank : 296)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	438	Target Neighborhood Hits	690	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CIC_HUMAN
NC score	0.087121 (rank : 297)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	438	Target Neighborhood Hits	992	Shared Neighborhood Hits	177
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FRK_HUMAN
NC score	0.087021 (rank : 298)	θ value	1.06291 (rank : 238)
Query Neighborhood Hits	438	Target Neighborhood Hits	1058	Shared Neighborhood Hits	169
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

MNT_MOUSE
NC score	0.086731 (rank : 299)	θ value	0.62314 (rank : 213)
Query Neighborhood Hits	438	Target Neighborhood Hits	432	Shared Neighborhood Hits	81
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

BSN_HUMAN
NC score	0.086424 (rank : 300)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	438	Target Neighborhood Hits	1537	Shared Neighborhood Hits	171
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SON_MOUSE
NC score	0.086419 (rank : 301)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	438	Target Neighborhood Hits	957	Shared Neighborhood Hits	129
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

PREX1_HUMAN
NC score	0.086327 (rank : 302)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	438	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

LYN_HUMAN
NC score	0.085885 (rank : 303)	θ value	0.163984 (rank : 145)
Query Neighborhood Hits	438	Target Neighborhood Hits	1022	Shared Neighborhood Hits	153
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

TIAM1_HUMAN
NC score	0.085309 (rank : 304)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	438	Target Neighborhood Hits	225	Shared Neighborhood Hits	35
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

LYN_MOUSE
NC score	0.085127 (rank : 305)	θ value	0.21417 (rank : 159)
Query Neighborhood Hits	438	Target Neighborhood Hits	1023	Shared Neighborhood Hits	154
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

WASF3_MOUSE
NC score	0.085107 (rank : 306)	θ value	4.03905 (rank : 346)
Query Neighborhood Hits	438	Target Neighborhood Hits	188	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

GGN_MOUSE
NC score	0.085050 (rank : 307)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	438	Target Neighborhood Hits	311	Shared Neighborhood Hits	66
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GAK17_HUMAN
NC score	0.085016 (rank : 308)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	438	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

GAK9_HUMAN
NC score	0.084923 (rank : 309)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	438	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

TIAM1_MOUSE
NC score	0.084667 (rank : 310)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	438	Target Neighborhood Hits	205	Shared Neighborhood Hits	29
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

GAK15_HUMAN
NC score	0.084532 (rank : 311)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	438	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P62688	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(I) Gag protein).

MUCDL_HUMAN
NC score	0.084405 (rank : 312)	θ value	1.81305 (rank : 289)
Query Neighborhood Hits	438	Target Neighborhood Hits	777	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

LPP_HUMAN
NC score	0.083948 (rank : 313)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	438	Target Neighborhood Hits	775	Shared Neighborhood Hits	175
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

SLY_MOUSE
NC score	0.083158 (rank : 314)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	438	Target Neighborhood Hits	108	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

ARHG3_HUMAN
NC score	0.082808 (rank : 315)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	438	Target Neighborhood Hits	82	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
NC score	0.082397 (rank : 316)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	438	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

GAK19_HUMAN
NC score	0.081817 (rank : 317)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	438	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

FMN2_HUMAN
NC score	0.081742 (rank : 318)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	438	Target Neighborhood Hits	484	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

SOX13_HUMAN
NC score	0.081368 (rank : 319)	θ value	0.163984 (rank : 150)
Query Neighborhood Hits	438	Target Neighborhood Hits	464	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

BIN1_MOUSE
NC score	0.081282 (rank : 320)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	438	Target Neighborhood Hits	283	Shared Neighborhood Hits	93
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

WBP11_MOUSE
NC score	0.081250 (rank : 321)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	438	Target Neighborhood Hits	362	Shared Neighborhood Hits	73
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

CEL_HUMAN
NC score	0.081237 (rank : 322)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	438	Target Neighborhood Hits	896	Shared Neighborhood Hits	171
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

BLK_HUMAN
NC score	0.080985 (rank : 323)	θ value	0.365318 (rank : 175)
Query Neighborhood Hits	438	Target Neighborhood Hits	994	Shared Neighborhood Hits	138
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

CRTC1_HUMAN
NC score	0.080626 (rank : 324)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	438	Target Neighborhood Hits	319	Shared Neighborhood Hits	100
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

FGD1_HUMAN
NC score	0.080449 (rank : 325)	θ value	0.279714 (rank : 168)
Query Neighborhood Hits	438	Target Neighborhood Hits	367	Shared Neighborhood Hits	77
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PRR13_MOUSE
NC score	0.080322 (rank : 326)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	438	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CN155_HUMAN
NC score	0.080118 (rank : 327)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	438	Target Neighborhood Hits	385	Shared Neighborhood Hits	68
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

ALEX_HUMAN
NC score	0.079841 (rank : 328)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	438	Target Neighborhood Hits	361	Shared Neighborhood Hits	84
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ATX2_MOUSE
NC score	0.079735 (rank : 329)	θ value	1.38821 (rank : 255)
Query Neighborhood Hits	438	Target Neighborhood Hits	445	Shared Neighborhood Hits	110
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BLNK_MOUSE
NC score	0.079613 (rank : 330)	θ value	3.0926 (rank : 311)
Query Neighborhood Hits	438	Target Neighborhood Hits	296	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

K0310_HUMAN
NC score	0.079589 (rank : 331)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	438	Target Neighborhood Hits	420	Shared Neighborhood Hits	96
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MCF2_HUMAN
NC score	0.079465 (rank : 332)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	438	Target Neighborhood Hits	166	Shared Neighborhood Hits	26
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MLL4_HUMAN
NC score	0.079327 (rank : 333)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	438	Target Neighborhood Hits	722	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CD2_HUMAN
NC score	0.079102 (rank : 334)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	438	Target Neighborhood Hits	504	Shared Neighborhood Hits	129
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

SF01_MOUSE
NC score	0.078970 (rank : 335)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	438	Target Neighborhood Hits	240	Shared Neighborhood Hits	61
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ARHG8_MOUSE
NC score	0.078613 (rank : 336)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	438	Target Neighborhood Hits	79	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

PELP1_MOUSE
NC score	0.078428 (rank : 337)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	438	Target Neighborhood Hits	709	Shared Neighborhood Hits	122
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

STS1_HUMAN
NC score	0.078415 (rank : 338)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	438	Target Neighborhood Hits	106	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

GAK14_HUMAN
NC score	0.078378 (rank : 339)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	438	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P62687	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_16p3.3 provirus ancestral Gag polyprotein (Gag polyprotein).

ARHGG_HUMAN
NC score	0.078194 (rank : 340)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	438	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

STS1_MOUSE
NC score	0.078157 (rank : 341)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	438	Target Neighborhood Hits	104	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

P85B_HUMAN
NC score	0.077810 (rank : 342)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	438	Target Neighborhood Hits	543	Shared Neighborhood Hits	88
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PTK6_HUMAN
NC score	0.077532 (rank : 343)	θ value	1.06291 (rank : 245)
Query Neighborhood Hits	438	Target Neighborhood Hits	1020	Shared Neighborhood Hits	154
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

SC24D_HUMAN
NC score	0.077420 (rank : 344)	θ value	0.279714 (rank : 170)
Query Neighborhood Hits	438	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

FMN1A_MOUSE
NC score	0.077169 (rank : 345)	θ value	1.38821 (rank : 262)
Query Neighborhood Hits	438	Target Neighborhood Hits	423	Shared Neighborhood Hits	75
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

RASA1_HUMAN
NC score	0.076657 (rank : 346)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	438	Target Neighborhood Hits	258	Shared Neighborhood Hits	65
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

PTK6_MOUSE
NC score	0.076610 (rank : 347)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	438	Target Neighborhood Hits	1026	Shared Neighborhood Hits	150
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

MYST3_HUMAN
NC score	0.076553 (rank : 348)	θ value	0.0330416 (rank : 98)
Query Neighborhood Hits	438	Target Neighborhood Hits	772	Shared Neighborhood Hits	84
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MUC2_HUMAN
NC score	0.076399 (rank : 349)	θ value	1.81305 (rank : 288)
Query Neighborhood Hits	438	Target Neighborhood Hits	906	Shared Neighborhood Hits	103
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ENAM_MOUSE
NC score	0.076225 (rank : 350)	θ value	0.21417 (rank : 157)
Query Neighborhood Hits	438	Target Neighborhood Hits	229	Shared Neighborhood Hits	58
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

FMN1B_MOUSE
NC score	0.076142 (rank : 351)	θ value	1.38821 (rank : 263)
Query Neighborhood Hits	438	Target Neighborhood Hits	447	Shared Neighborhood Hits	77
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

CS016_HUMAN
NC score	0.076010 (rank : 352)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	438	Target Neighborhood Hits	310	Shared Neighborhood Hits	66
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

GAK13_HUMAN
NC score	0.075760 (rank : 353)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	438	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	P62686	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Gag polyprotein (Gag polyprotein).

K1688_MOUSE
NC score	0.075684 (rank : 354)	θ value	1.06291 (rank : 240)
Query Neighborhood Hits	438	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

ARHG8_HUMAN
NC score	0.075403 (rank : 355)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	438	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

CO039_MOUSE
NC score	0.074941 (rank : 356)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	438	Target Neighborhood Hits	445	Shared Neighborhood Hits	118
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

TPO_MOUSE
NC score	0.074923 (rank : 357)	θ value	0.47712 (rank : 205)
Query Neighborhood Hits	438	Target Neighborhood Hits	258	Shared Neighborhood Hits	74
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

PRR13_HUMAN
NC score	0.074781 (rank : 358)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	438	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

MYST3_MOUSE
NC score	0.074601 (rank : 359)	θ value	0.0330416 (rank : 99)
Query Neighborhood Hits	438	Target Neighborhood Hits	688	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

BLK_MOUSE
NC score	0.074239 (rank : 360)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	438	Target Neighborhood Hits	992	Shared Neighborhood Hits	131
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

TXND2_HUMAN
NC score	0.073870 (rank : 361)	θ value	1.06291 (rank : 251)
Query Neighborhood Hits	438	Target Neighborhood Hits	793	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TRI66_HUMAN
NC score	0.073631 (rank : 362)	θ value	0.00665767 (rank : 74)
Query Neighborhood Hits	438	Target Neighborhood Hits	479	Shared Neighborhood Hits	71
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SLY_HUMAN
NC score	0.073096 (rank : 363)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	438	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

ARHGA_MOUSE
NC score	0.073067 (rank : 364)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	438	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

PPIP2_HUMAN
NC score	0.072778 (rank : 365)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	438	Target Neighborhood Hits	254	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

HGS_MOUSE
NC score	0.072769 (rank : 366)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	438	Target Neighborhood Hits	589	Shared Neighborhood Hits	104
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

SOX13_MOUSE
NC score	0.072525 (rank : 367)	θ value	0.0736092 (rank : 118)
Query Neighborhood Hits	438	Target Neighborhood Hits	495	Shared Neighborhood Hits	108
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

DOK1_HUMAN
NC score	0.072159 (rank : 368)	θ value	0.0113563 (rank : 81)
Query Neighborhood Hits	438	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

BAG3_MOUSE
NC score	0.071992 (rank : 369)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	438	Target Neighborhood Hits	513	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

ARHGF_HUMAN
NC score	0.071687 (rank : 370)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	438	Target Neighborhood Hits	214	Shared Neighborhood Hits	52
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

P85B_MOUSE
NC score	0.071421 (rank : 371)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	438	Target Neighborhood Hits	519	Shared Neighborhood Hits	80
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SRRM2_MOUSE
NC score	0.071147 (rank : 372)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	438	Target Neighborhood Hits	1470	Shared Neighborhood Hits	172
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PCQAP_HUMAN
NC score	0.071126 (rank : 373)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	438	Target Neighborhood Hits	549	Shared Neighborhood Hits	86
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

ZIMP7_MOUSE
NC score	0.071089 (rank : 374)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	438	Target Neighborhood Hits	566	Shared Neighborhood Hits	129
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

SSBP4_HUMAN
NC score	0.071084 (rank : 375)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	438	Target Neighborhood Hits	753	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TXK_MOUSE
NC score	0.071066 (rank : 376)	θ value	3.0926 (rank : 329)
Query Neighborhood Hits	438	Target Neighborhood Hits	980	Shared Neighborhood Hits	135
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

WASP_MOUSE
NC score	0.070937 (rank : 377)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	438	Target Neighborhood Hits	223	Shared Neighborhood Hits	50
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CSK_HUMAN
NC score	0.070932 (rank : 378)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	438	Target Neighborhood Hits	1009	Shared Neighborhood Hits	132
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
NC score	0.070895 (rank : 379)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	438	Target Neighborhood Hits	1009	Shared Neighborhood Hits	132
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

SHC1_HUMAN
NC score	0.070762 (rank : 380)	θ value	4.03905 (rank : 343)
Query Neighborhood Hits	438	Target Neighborhood Hits	170	Shared Neighborhood Hits	59
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

PI5PA_HUMAN
NC score	0.070582 (rank : 381)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	438	Target Neighborhood Hits	749	Shared Neighborhood Hits	162
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

K1802_HUMAN
NC score	0.070498 (rank : 382)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	438	Target Neighborhood Hits	1378	Shared Neighborhood Hits	182
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ZIM10_HUMAN
NC score	0.070335 (rank : 383)	θ value	4.03905 (rank : 348)
Query Neighborhood Hits	438	Target Neighborhood Hits	577	Shared Neighborhood Hits	133
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

BI2L1_HUMAN
NC score	0.070293 (rank : 384)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	438	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

WASP_HUMAN
NC score	0.069907 (rank : 385)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	438	Target Neighborhood Hits	195	Shared Neighborhood Hits	54
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

TAB3_HUMAN
NC score	0.069712 (rank : 386)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	438	Target Neighborhood Hits	168	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

PPIP2_MOUSE
NC score	0.069636 (rank : 387)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	438	Target Neighborhood Hits	308	Shared Neighborhood Hits	21
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

ABL1_MOUSE
NC score	0.069615 (rank : 388)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	438	Target Neighborhood Hits	1178	Shared Neighborhood Hits	151
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PO6F2_MOUSE
NC score	0.069217 (rank : 389)	θ value	0.00869519 (rank : 80)
Query Neighborhood Hits	438	Target Neighborhood Hits	639	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

SC24A_MOUSE
NC score	0.069209 (rank : 390)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	438	Target Neighborhood Hits	394	Shared Neighborhood Hits	120
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

ZN645_HUMAN
NC score	0.068947 (rank : 391)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	438	Target Neighborhood Hits	265	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

RPB1_MOUSE
NC score	0.068855 (rank : 392)	θ value	0.813845 (rank : 226)
Query Neighborhood Hits	438	Target Neighborhood Hits	363	Shared Neighborhood Hits	64
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SYNPO_MOUSE
NC score	0.068818 (rank : 393)	θ value	0.813845 (rank : 229)
Query Neighborhood Hits	438	Target Neighborhood Hits	242	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

RPB1_HUMAN
NC score	0.068575 (rank : 394)	θ value	0.813845 (rank : 225)
Query Neighborhood Hits	438	Target Neighborhood Hits	362	Shared Neighborhood Hits	64
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SELPL_MOUSE
NC score	0.068366 (rank : 395)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	438	Target Neighborhood Hits	588	Shared Neighborhood Hits	117
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

HGS_HUMAN
NC score	0.068365 (rank : 396)	θ value	6.88961 (rank : 392)
Query Neighborhood Hits	438	Target Neighborhood Hits	517	Shared Neighborhood Hits	83
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

ABL1_HUMAN
NC score	0.068293 (rank : 397)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	438	Target Neighborhood Hits	1220	Shared Neighborhood Hits	149
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

FGD1_MOUSE
NC score	0.068154 (rank : 398)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	438	Target Neighborhood Hits	387	Shared Neighborhood Hits	78
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CJ078_MOUSE
NC score	0.067866 (rank : 399)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	438	Target Neighborhood Hits	559	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

LCK_HUMAN
NC score	0.067787 (rank : 400)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	438	Target Neighborhood Hits	987	Shared Neighborhood Hits	116
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

ARHGA_HUMAN
NC score	0.067651 (rank : 401)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	438	Target Neighborhood Hits	187	Shared Neighborhood Hits	26
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

GGN_HUMAN
NC score	0.067370 (rank : 402)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	438	Target Neighborhood Hits	269	Shared Neighborhood Hits	65
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

TROAP_HUMAN
NC score	0.067348 (rank : 403)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	438	Target Neighborhood Hits	258	Shared Neighborhood Hits	67
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TEC_HUMAN
NC score	0.067254 (rank : 404)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	438	Target Neighborhood Hits	1006	Shared Neighborhood Hits	137
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

LCK_MOUSE
NC score	0.067043 (rank : 405)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	438	Target Neighborhood Hits	981	Shared Neighborhood Hits	114
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

SH21B_MOUSE
NC score	0.066973 (rank : 406)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	438	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

3BP1_HUMAN
NC score	0.066756 (rank : 407)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	438	Target Neighborhood Hits	376	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ATX2_HUMAN
NC score	0.066608 (rank : 408)	θ value	1.81305 (rank : 280)
Query Neighborhood Hits	438	Target Neighborhood Hits	375	Shared Neighborhood Hits	75
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ECT2_MOUSE
NC score	0.066237 (rank : 409)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	438	Target Neighborhood Hits	98	Shared Neighborhood Hits	23
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

SET1A_HUMAN
NC score	0.066199 (rank : 410)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	438	Target Neighborhood Hits	690	Shared Neighborhood Hits	85
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

NFRKB_MOUSE
NC score	0.066192 (rank : 411)	θ value	1.06291 (rank : 241)
Query Neighborhood Hits	438	Target Neighborhood Hits	393	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

TEC_MOUSE
NC score	0.066069 (rank : 412)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	438	Target Neighborhood Hits	1006	Shared Neighborhood Hits	136
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

CSKI2_MOUSE
NC score	0.065981 (rank : 413)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	438	Target Neighborhood Hits	812	Shared Neighborhood Hits	137
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TXK_HUMAN
NC score	0.065980 (rank : 414)	θ value	6.88961 (rank : 411)
Query Neighborhood Hits	438	Target Neighborhood Hits	971	Shared Neighborhood Hits	126
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

PTN23_MOUSE
NC score	0.065922 (rank : 415)	θ value	0.0736092 (rank : 117)
Query Neighborhood Hits	438	Target Neighborhood Hits	726	Shared Neighborhood Hits	122
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SH21B_HUMAN
NC score	0.065841 (rank : 416)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	438	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

IF4G1_MOUSE
NC score	0.065838 (rank : 417)	θ value	0.163984 (rank : 144)
Query Neighborhood Hits	438	Target Neighborhood Hits	534	Shared Neighborhood Hits	109
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MINT_MOUSE
NC score	0.065807 (rank : 418)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	438	Target Neighborhood Hits	1514	Shared Neighborhood Hits	172
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ZN207_HUMAN
NC score	0.065678 (rank : 419)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	438	Target Neighborhood Hits	326	Shared Neighborhood Hits	47
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

JIP1_HUMAN
NC score	0.065491 (rank : 420)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	438	Target Neighborhood Hits	271	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

PSL1_HUMAN
NC score	0.065411 (rank : 421)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	438	Target Neighborhood Hits	650	Shared Neighborhood Hits	143
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

BCR_HUMAN
NC score	0.065404 (rank : 422)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	438	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

MTSS1_MOUSE
NC score	0.065317 (rank : 423)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	438	Target Neighborhood Hits	592	Shared Neighborhood Hits	114
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

GPS2_HUMAN
NC score	0.065156 (rank : 424)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	438	Target Neighborhood Hits	459	Shared Neighborhood Hits	84
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

JIP1_MOUSE
NC score	0.065033 (rank : 425)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	438	Target Neighborhood Hits	259	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

DAPP1_MOUSE
NC score	0.064869 (rank : 426)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	438	Target Neighborhood Hits	225	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

ITK_HUMAN
NC score	0.064758 (rank : 427)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	438	Target Neighborhood Hits	1016	Shared Neighborhood Hits	132
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

HAPIP_HUMAN
NC score	0.064756 (rank : 428)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	438	Target Neighborhood Hits	350	Shared Neighborhood Hits	28
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

FMN2_MOUSE
NC score	0.064695 (rank : 429)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	438	Target Neighborhood Hits	349	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

DAPP1_HUMAN
NC score	0.064583 (rank : 430)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

OBF1_HUMAN
NC score	0.064386 (rank : 431)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	438	Target Neighborhood Hits	203	Shared Neighborhood Hits	77
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

ECT2_HUMAN
NC score	0.064148 (rank : 432)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	438	Target Neighborhood Hits	98	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

SMR3A_HUMAN
NC score	0.064063 (rank : 433)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	438	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

GRB14_MOUSE
NC score	0.063805 (rank : 434)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	438	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

ARHGB_HUMAN
NC score	0.063563 (rank : 435)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	438	Target Neighborhood Hits	375	Shared Neighborhood Hits	43
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

MILK1_MOUSE
NC score	0.063550 (rank : 436)	θ value	3.0926 (rank : 322)
Query Neighborhood Hits	438	Target Neighborhood Hits	788	Shared Neighborhood Hits	151
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

GRB14_HUMAN
NC score	0.062903 (rank : 437)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	438	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

TRI66_MOUSE
NC score	0.062872 (rank : 438)	θ value	1.38821 (rank : 277)
Query Neighborhood Hits	438	Target Neighborhood Hits	491	Shared Neighborhood Hits	80
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

S23IP_HUMAN
NC score	0.062807 (rank : 439)	θ value	1.81305 (rank : 291)
Query Neighborhood Hits	438	Target Neighborhood Hits	134	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

ABL2_HUMAN
NC score	0.062779 (rank : 440)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	438	Target Neighborhood Hits	1045	Shared Neighborhood Hits	125
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

FMNL_HUMAN
NC score	0.062693 (rank : 441)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	438	Target Neighborhood Hits	529	Shared Neighborhood Hits	87
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

ARHGC_HUMAN
NC score	0.062657 (rank : 442)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	438	Target Neighborhood Hits	351	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SF3A1_MOUSE
NC score	0.062553 (rank : 443)	θ value	5.27518 (rank : 376)
Query Neighborhood Hits	438	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

HRX_HUMAN
NC score	0.062540 (rank : 444)	θ value	0.47712 (rank : 194)
Query Neighborhood Hits	438	Target Neighborhood Hits	825	Shared Neighborhood Hits	72
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ARHGC_MOUSE
NC score	0.062518 (rank : 445)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	438	Target Neighborhood Hits	344	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LCP2_MOUSE
NC score	0.062103 (rank : 446)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	438	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SASH1_HUMAN
NC score	0.061995 (rank : 447)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	438	Target Neighborhood Hits	292	Shared Neighborhood Hits	92
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

PCQAP_MOUSE
NC score	0.061966 (rank : 448)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	438	Target Neighborhood Hits	506	Shared Neighborhood Hits	77
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

CRSP2_HUMAN
NC score	0.061729 (rank : 449)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	438	Target Neighborhood Hits	380	Shared Neighborhood Hits	99
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

PRG4_HUMAN
NC score	0.061717 (rank : 450)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	438	Target Neighborhood Hits	764	Shared Neighborhood Hits	98
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CIKS_HUMAN
NC score	0.061460 (rank : 451)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	438	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

APS_HUMAN
NC score	0.061182 (rank : 452)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	438	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

R3HD1_HUMAN
NC score	0.061170 (rank : 453)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	438	Target Neighborhood Hits	203	Shared Neighborhood Hits	50
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

SRMS_MOUSE
NC score	0.061105 (rank : 454)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	438	Target Neighborhood Hits	964	Shared Neighborhood Hits	107
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

BAT3_HUMAN
NC score	0.061017 (rank : 455)	θ value	1.81305 (rank : 281)
Query Neighborhood Hits	438	Target Neighborhood Hits	490	Shared Neighborhood Hits	92
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

SHC3_MOUSE
NC score	0.060960 (rank : 456)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	438	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

ARHG1_HUMAN
NC score	0.060694 (rank : 457)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	438	Target Neighborhood Hits	176	Shared Neighborhood Hits	26
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

SRRM2_HUMAN
NC score	0.060396 (rank : 458)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	438	Target Neighborhood Hits	1296	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SH22A_MOUSE
NC score	0.060299 (rank : 459)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	438	Target Neighborhood Hits	179	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

EPN1_HUMAN
NC score	0.060183 (rank : 460)	θ value	0.62314 (rank : 210)
Query Neighborhood Hits	438	Target Neighborhood Hits	206	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

SFR15_HUMAN
NC score	0.060181 (rank : 461)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	438	Target Neighborhood Hits	368	Shared Neighborhood Hits	67
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

PDC6I_HUMAN
NC score	0.060051 (rank : 462)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	438	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

CIC_MOUSE
NC score	0.059877 (rank : 463)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	438	Target Neighborhood Hits	742	Shared Neighborhood Hits	129
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SASH1_MOUSE
NC score	0.059709 (rank : 464)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	438	Target Neighborhood Hits	263	Shared Neighborhood Hits	77
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

JIP2_HUMAN
NC score	0.059708 (rank : 465)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	438	Target Neighborhood Hits	288	Shared Neighborhood Hits	87
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

TARA_HUMAN
NC score	0.059670 (rank : 466)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	438	Target Neighborhood Hits	1626	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SPR1B_MOUSE
NC score	0.059270 (rank : 467)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	438	Target Neighborhood Hits	395	Shared Neighborhood Hits	109
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

CSKI2_HUMAN
NC score	0.059085 (rank : 468)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	438	Target Neighborhood Hits	747	Shared Neighborhood Hits	105
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

SHE_MOUSE
NC score	0.059032 (rank : 469)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	438	Target Neighborhood Hits	169	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

CIZ1_HUMAN
NC score	0.058759 (rank : 470)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	438	Target Neighborhood Hits	359	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

FGD3_MOUSE
NC score	0.058555 (rank : 471)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	438	Target Neighborhood Hits	257	Shared Neighborhood Hits	30
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

RTP3_MOUSE
NC score	0.058423 (rank : 472)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	438	Target Neighborhood Hits	374	Shared Neighborhood Hits	94
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

AUTS2_HUMAN
NC score	0.058416 (rank : 473)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	438	Target Neighborhood Hits	342	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

PRPC_HUMAN
NC score	0.058381 (rank : 474)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	438	Target Neighborhood Hits	165	Shared Neighborhood Hits	34
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

GRB7_MOUSE
NC score	0.058321 (rank : 475)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	438	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

SHC1_MOUSE
NC score	0.058300 (rank : 476)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	438	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

MYO15_HUMAN
NC score	0.058205 (rank : 477)	θ value	2.36792 (rank : 299)
Query Neighborhood Hits	438	Target Neighborhood Hits	671	Shared Neighborhood Hits	170
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SHE_HUMAN
NC score	0.058170 (rank : 478)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	438	Target Neighborhood Hits	164	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHD_HUMAN
NC score	0.057756 (rank : 479)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	438	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

LDB3_MOUSE
NC score	0.057663 (rank : 480)	θ value	0.279714 (rank : 169)
Query Neighborhood Hits	438	Target Neighborhood Hits	510	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

SHB_MOUSE
NC score	0.057608 (rank : 481)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	438	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

ABR_HUMAN
NC score	0.057510 (rank : 482)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	438	Target Neighborhood Hits	166	Shared Neighborhood Hits	37
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

GAB1_HUMAN
NC score	0.057502 (rank : 483)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	438	Target Neighborhood Hits	279	Shared Neighborhood Hits	79
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PRR8_HUMAN
NC score	0.057465 (rank : 484)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	438	Target Neighborhood Hits	217	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

SHC2_HUMAN
NC score	0.057383 (rank : 485)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	438	Target Neighborhood Hits	170	Shared Neighborhood Hits	55
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

ITK_MOUSE
NC score	0.057333 (rank : 486)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	438	Target Neighborhood Hits	985	Shared Neighborhood Hits	116
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

ARHG1_MOUSE
NC score	0.057196 (rank : 487)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	438	Target Neighborhood Hits	266	Shared Neighborhood Hits	50
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

EPN1_MOUSE
NC score	0.057121 (rank : 488)	θ value	1.38821 (rank : 260)
Query Neighborhood Hits	438	Target Neighborhood Hits	240	Shared Neighborhood Hits	55
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

SHC2_MOUSE
NC score	0.057100 (rank : 489)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	438	Target Neighborhood Hits	144	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

P55G_HUMAN
NC score	0.057087 (rank : 490)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	438	Target Neighborhood Hits	451	Shared Neighborhood Hits	57
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CECR2_HUMAN
NC score	0.057050 (rank : 491)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	438	Target Neighborhood Hits	543	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

ZYX_HUMAN
NC score	0.056938 (rank : 492)	θ value	0.279714 (rank : 174)
Query Neighborhood Hits	438	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

SHC3_HUMAN
NC score	0.056889 (rank : 493)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	438	Target Neighborhood Hits	155	Shared Neighborhood Hits	45
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

FGD4_MOUSE
NC score	0.056698 (rank : 494)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

LNK_HUMAN
NC score	0.056697 (rank : 495)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	438	Target Neighborhood Hits	151	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

SNPC4_HUMAN
NC score	0.056627 (rank : 496)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	438	Target Neighborhood Hits	589	Shared Neighborhood Hits	121
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SF3A1_HUMAN
NC score	0.056604 (rank : 497)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	438	Target Neighborhood Hits	199	Shared Neighborhood Hits	47
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

RGNEF_MOUSE
NC score	0.056431 (rank : 498)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	438	Target Neighborhood Hits	641	Shared Neighborhood Hits	53
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

FGD4_HUMAN
NC score	0.056346 (rank : 499)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	438	Target Neighborhood Hits	219	Shared Neighborhood Hits	29
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

MINT_HUMAN
NC score	0.056026 (rank : 500)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	438	Target Neighborhood Hits	1291	Shared Neighborhood Hits	124
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GA2L2_MOUSE
NC score	0.055972 (rank : 501)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	438	Target Neighborhood Hits	395	Shared Neighborhood Hits	103
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

FYB_HUMAN
NC score	0.055928 (rank : 502)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	438	Target Neighborhood Hits	379	Shared Neighborhood Hits	81
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

MATK_HUMAN
NC score	0.055907 (rank : 503)	θ value	1.81305 (rank : 286)
Query Neighborhood Hits	438	Target Neighborhood Hits	954	Shared Neighborhood Hits	84
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

SYP2L_MOUSE
NC score	0.055877 (rank : 504)	θ value	1.06291 (rank : 250)
Query Neighborhood Hits	438	Target Neighborhood Hits	289	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

P55G_MOUSE
NC score	0.055782 (rank : 505)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	438	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

SHD_MOUSE
NC score	0.055721 (rank : 506)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	438	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

FGD2_HUMAN
NC score	0.055688 (rank : 507)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	438	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

SHB_HUMAN
NC score	0.055642 (rank : 508)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	438	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

BI2L1_MOUSE
NC score	0.055627 (rank : 509)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	438	Target Neighborhood Hits	197	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

ACK1_HUMAN
NC score	0.055457 (rank : 510)	θ value	1.81305 (rank : 278)
Query Neighborhood Hits	438	Target Neighborhood Hits	1140	Shared Neighborhood Hits	162
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
NC score	0.055026 (rank : 511)	θ value	0.21417 (rank : 156)
Query Neighborhood Hits	438	Target Neighborhood Hits	1080	Shared Neighborhood Hits	153
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

GAB1_MOUSE
NC score	0.055008 (rank : 512)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	438	Target Neighborhood Hits	233	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

BAT3_MOUSE
NC score	0.055001 (rank : 513)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	438	Target Neighborhood Hits	518	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

MATK_MOUSE
NC score	0.054949 (rank : 514)	θ value	1.81305 (rank : 287)
Query Neighborhood Hits	438	Target Neighborhood Hits	952	Shared Neighborhood Hits	88
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

SRMS_HUMAN
NC score	0.054879 (rank : 515)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	438	Target Neighborhood Hits	946	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

EM55_HUMAN
NC score	0.054765 (rank : 516)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	438	Target Neighborhood Hits	228	Shared Neighborhood Hits	90
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

BAIP2_MOUSE
NC score	0.054755 (rank : 517)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	438	Target Neighborhood Hits	185	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

LBC_HUMAN
NC score	0.054722 (rank : 518)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	438	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

FGD3_HUMAN
NC score	0.054697 (rank : 519)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	438	Target Neighborhood Hits	249	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

CO039_HUMAN
NC score	0.054529 (rank : 520)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	438	Target Neighborhood Hits	264	Shared Neighborhood Hits	58
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CHIN_MOUSE
NC score	0.054504 (rank : 521)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	438	Target Neighborhood Hits	229	Shared Neighborhood Hits	51
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

PKHG4_HUMAN
NC score	0.054480 (rank : 522)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	438	Target Neighborhood Hits	200	Shared Neighborhood Hits	37
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

LDB3_HUMAN
NC score	0.054438 (rank : 523)	θ value	1.81305 (rank : 285)
Query Neighborhood Hits	438	Target Neighborhood Hits	497	Shared Neighborhood Hits	71
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

WBP2_HUMAN
NC score	0.054359 (rank : 524)	θ value	6.88961 (rank : 413)
Query Neighborhood Hits	438	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	Q969T9, O95638	Gene names	WBP2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

DLG5_HUMAN
NC score	0.054355 (rank : 525)	θ value	0.125558 (rank : 139)
Query Neighborhood Hits	438	Target Neighborhood Hits	1088	Shared Neighborhood Hits	97
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

BAZ2A_MOUSE
NC score	0.054162 (rank : 526)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	438	Target Neighborhood Hits	744	Shared Neighborhood Hits	117
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

SYNPO_HUMAN
NC score	0.053938 (rank : 527)	θ value	2.36792 (rank : 307)
Query Neighborhood Hits	438	Target Neighborhood Hits	281	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

K1688_HUMAN
NC score	0.053920 (rank : 528)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	438	Target Neighborhood Hits	217	Shared Neighborhood Hits	55
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

PDC6I_MOUSE
NC score	0.053831 (rank : 529)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	438	Target Neighborhood Hits	275	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PO6F2_HUMAN
NC score	0.053797 (rank : 530)	θ value	2.36792 (rank : 302)
Query Neighborhood Hits	438	Target Neighborhood Hits	618	Shared Neighborhood Hits	87
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

CHIN_HUMAN
NC score	0.053695 (rank : 531)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

ZYX_MOUSE
NC score	0.053691 (rank : 532)	θ value	1.81305 (rank : 293)
Query Neighborhood Hits	438	Target Neighborhood Hits	347	Shared Neighborhood Hits	59
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

GRB7_HUMAN
NC score	0.053667 (rank : 533)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	438	Target Neighborhood Hits	156	Shared Neighborhood Hits	52
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

DIAP1_HUMAN
NC score	0.053656 (rank : 534)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	438	Target Neighborhood Hits	784	Shared Neighborhood Hits	74
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

SYP2L_HUMAN
NC score	0.053654 (rank : 535)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	438	Target Neighborhood Hits	400	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

FGD2_MOUSE
NC score	0.053430 (rank : 536)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	438	Target Neighborhood Hits	163	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

ANK2_HUMAN
NC score	0.053378 (rank : 537)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	438	Target Neighborhood Hits	1615	Shared Neighborhood Hits	170
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

HSH2D_HUMAN
NC score	0.053281 (rank : 538)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	438	Target Neighborhood Hits	159	Shared Neighborhood Hits	39
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

NFH_MOUSE
NC score	0.053230 (rank : 539)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	438	Target Neighborhood Hits	2247	Shared Neighborhood Hits	190
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MYO15_MOUSE
NC score	0.053139 (rank : 540)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	438	Target Neighborhood Hits	467	Shared Neighborhood Hits	119
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

IGEB_MOUSE
NC score	0.053062 (rank : 541)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	438	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P03975	Gene names	Iap
Domain Architecture
Description	IgE-binding protein.

LNK_MOUSE
NC score	0.053023 (rank : 542)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	438	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

GNRP_MOUSE
NC score	0.053020 (rank : 543)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	438	Target Neighborhood Hits	191	Shared Neighborhood Hits	24
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

BAIP2_HUMAN
NC score	0.053014 (rank : 544)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	438	Target Neighborhood Hits	192	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

DIDO1_HUMAN
NC score	0.052950 (rank : 545)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	438	Target Neighborhood Hits	960	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

RBM12_MOUSE
NC score	0.052840 (rank : 546)	θ value	5.27518 (rank : 374)
Query Neighborhood Hits	438	Target Neighborhood Hits	313	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

CD248_HUMAN
NC score	0.052741 (rank : 547)	θ value	1.06291 (rank : 236)
Query Neighborhood Hits	438	Target Neighborhood Hits	679	Shared Neighborhood Hits	128
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

PTN23_HUMAN
NC score	0.052734 (rank : 548)	θ value	2.36792 (rank : 303)
Query Neighborhood Hits	438	Target Neighborhood Hits	646	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CHIO_HUMAN
NC score	0.052551 (rank : 549)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	438	Target Neighborhood Hits	220	Shared Neighborhood Hits	48
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

ANTR1_MOUSE
NC score	0.052420 (rank : 550)	θ value	5.27518 (rank : 354)
Query Neighborhood Hits	438	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

CK056_MOUSE
NC score	0.052387 (rank : 551)	θ value	1.38821 (rank : 258)
Query Neighborhood Hits	438	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U2I3, Q3TWF5, Q6P543, Q80T93, Q811J6, Q8BI34, Q8VE55	Gene names	Kiaa1759
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf56 homolog.

EM55_MOUSE
NC score	0.052329 (rank : 552)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	438	Target Neighborhood Hits	221	Shared Neighborhood Hits	85
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

MUC5B_HUMAN
NC score	0.052315 (rank : 553)	θ value	0.813845 (rank : 222)
Query Neighborhood Hits	438	Target Neighborhood Hits	1020	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

T22D4_HUMAN
NC score	0.052211 (rank : 554)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	438	Target Neighborhood Hits	403	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

LR37A_HUMAN
NC score	0.052135 (rank : 555)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	438	Target Neighborhood Hits	720	Shared Neighborhood Hits	111
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

TM108_MOUSE
NC score	0.052094 (rank : 556)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	438	Target Neighborhood Hits	336	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

GRB10_MOUSE
NC score	0.052017 (rank : 557)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	438	Target Neighborhood Hits	156	Shared Neighborhood Hits	49
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

TENS4_MOUSE
NC score	0.051899 (rank : 558)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	438	Target Neighborhood Hits	225	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

AB1IP_HUMAN
NC score	0.051767 (rank : 559)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	438	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

PO121_HUMAN
NC score	0.051542 (rank : 560)	θ value	3.0926 (rank : 323)
Query Neighborhood Hits	438	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PELP1_HUMAN
NC score	0.051298 (rank : 561)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	438	Target Neighborhood Hits	596	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

S3TC1_HUMAN
NC score	0.051239 (rank : 562)	θ value	3.0926 (rank : 326)
Query Neighborhood Hits	438	Target Neighborhood Hits	78	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

MGR1_HUMAN
NC score	0.051053 (rank : 563)	θ value	9.29e-05 (rank : 28)
Query Neighborhood Hits	438	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

RHG09_HUMAN
NC score	0.051045 (rank : 564)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	438	Target Neighborhood Hits	186	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

JIP2_MOUSE
NC score	0.051031 (rank : 565)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	438	Target Neighborhood Hits	144	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

ARHG2_HUMAN
NC score	0.050929 (rank : 566)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	438	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

3BP1_MOUSE
NC score	0.050801 (rank : 567)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	438	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

TULP4_HUMAN
NC score	0.050756 (rank : 568)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	438	Target Neighborhood Hits	426	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

WBP2_MOUSE
NC score	0.050538 (rank : 569)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	438	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	P97765	Gene names	Wbp2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

EP400_MOUSE
NC score	0.050529 (rank : 570)	θ value	1.38821 (rank : 259)
Query Neighborhood Hits	438	Target Neighborhood Hits	592	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ARHG2_MOUSE
NC score	0.050324 (rank : 571)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	438	Target Neighborhood Hits	120	Shared Neighborhood Hits	24
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ENAM_HUMAN
NC score	0.050277 (rank : 572)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	438	Target Neighborhood Hits	227	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

VASP_HUMAN
NC score	0.047417 (rank : 573)	θ value	6.88961 (rank : 412)
Query Neighborhood Hits	438	Target Neighborhood Hits	201	Shared Neighborhood Hits	48
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WNK2_HUMAN
NC score	0.046663 (rank : 574)	θ value	6.88961 (rank : 414)
Query Neighborhood Hits	438	Target Neighborhood Hits	1407	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

TAU_MOUSE
NC score	0.045781 (rank : 575)	θ value	5.27518 (rank : 378)
Query Neighborhood Hits	438	Target Neighborhood Hits	502	Shared Neighborhood Hits	86
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

MAML2_HUMAN
NC score	0.044961 (rank : 576)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	438	Target Neighborhood Hits	360	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

RBM16_HUMAN
NC score	0.044322 (rank : 577)	θ value	4.03905 (rank : 342)
Query Neighborhood Hits	438	Target Neighborhood Hits	300	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

PDLI7_HUMAN
NC score	0.043085 (rank : 578)	θ value	1.38821 (rank : 271)
Query Neighborhood Hits	438	Target Neighborhood Hits	547	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PI5PA_MOUSE
NC score	0.042756 (rank : 579)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	438	Target Neighborhood Hits	331	Shared Neighborhood Hits	75
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

IQEC2_MOUSE
NC score	0.042057 (rank : 580)	θ value	1.81305 (rank : 283)
Query Neighborhood Hits	438	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

CJ055_HUMAN
NC score	0.041880 (rank : 581)	θ value	1.38821 (rank : 257)
Query Neighborhood Hits	438	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SWW7, Q8NAK4	Gene names	C10orf55
Domain Architecture	No domain graphic available
Description	Protein C10orf55.

SF04_HUMAN
NC score	0.041807 (rank : 582)	θ value	0.21417 (rank : 164)
Query Neighborhood Hits	438	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

AAK1_HUMAN
NC score	0.041646 (rank : 583)	θ value	1.06291 (rank : 234)
Query Neighborhood Hits	438	Target Neighborhood Hits	1077	Shared Neighborhood Hits	130
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

LOXL1_MOUSE
NC score	0.041267 (rank : 584)	θ value	0.47712 (rank : 195)
Query Neighborhood Hits	438	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

MGR1_MOUSE
NC score	0.041177 (rank : 585)	θ value	0.0252991 (rank : 95)
Query Neighborhood Hits	438	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

SIN3A_MOUSE
NC score	0.040378 (rank : 586)	θ value	1.06291 (rank : 249)
Query Neighborhood Hits	438	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

PDZD2_HUMAN
NC score	0.040112 (rank : 587)	θ value	5.27518 (rank : 371)
Query Neighborhood Hits	438	Target Neighborhood Hits	772	Shared Neighborhood Hits	99
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SSBP3_HUMAN
NC score	0.039808 (rank : 588)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	438	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.039808 (rank : 589)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	438	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

IQEC2_HUMAN
NC score	0.039452 (rank : 590)	θ value	1.81305 (rank : 282)
Query Neighborhood Hits	438	Target Neighborhood Hits	403	Shared Neighborhood Hits	65
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

MEF2B_MOUSE
NC score	0.039440 (rank : 591)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	438	Target Neighborhood Hits	218	Shared Neighborhood Hits	58
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

TTBK1_HUMAN
NC score	0.039109 (rank : 592)	θ value	0.0961366 (rank : 137)
Query Neighborhood Hits	438	Target Neighborhood Hits	1058	Shared Neighborhood Hits	76
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

SIN3A_HUMAN
NC score	0.039064 (rank : 593)	θ value	5.27518 (rank : 377)
Query Neighborhood Hits	438	Target Neighborhood Hits	180	Shared Neighborhood Hits	47
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

PLS1_MOUSE
NC score	0.039006 (rank : 594)	θ value	0.21417 (rank : 161)
Query Neighborhood Hits	438	Target Neighborhood Hits	58	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJ00, O54730, O54731, Q9D1F8	Gene names	Plscr1, Tra1b, Tras1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Transplantability-associated protein 1) (TRA1) (NOR1).

MKL1_HUMAN
NC score	0.039001 (rank : 595)	θ value	5.27518 (rank : 368)
Query Neighborhood Hits	438	Target Neighborhood Hits	232	Shared Neighborhood Hits	35
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

PER2_MOUSE
NC score	0.038938 (rank : 596)	θ value	4.03905 (rank : 340)
Query Neighborhood Hits	438	Target Neighborhood Hits	325	Shared Neighborhood Hits	84
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

LPP_MOUSE
NC score	0.038780 (rank : 597)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	438	Target Neighborhood Hits	247	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

WDR33_HUMAN
NC score	0.038637 (rank : 598)	θ value	0.62314 (rank : 219)
Query Neighborhood Hits	438	Target Neighborhood Hits	638	Shared Neighborhood Hits	71
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

SPEG_MOUSE
NC score	0.038593 (rank : 599)	θ value	0.21417 (rank : 165)
Query Neighborhood Hits	438	Target Neighborhood Hits	1959	Shared Neighborhood Hits	189
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SC24B_HUMAN
NC score	0.038545 (rank : 600)	θ value	0.813845 (rank : 227)
Query Neighborhood Hits	438	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

RCOR2_MOUSE
NC score	0.037985 (rank : 601)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	438	Target Neighborhood Hits	107	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

PRGC2_HUMAN
NC score	0.037343 (rank : 602)	θ value	4.03905 (rank : 341)
Query Neighborhood Hits	438	Target Neighborhood Hits	272	Shared Neighborhood Hits	52
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

RCOR2_HUMAN
NC score	0.036830 (rank : 603)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	438	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

WHRN_MOUSE
NC score	0.036629 (rank : 604)	θ value	1.81305 (rank : 292)
Query Neighborhood Hits	438	Target Neighborhood Hits	412	Shared Neighborhood Hits	65
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PO6F1_MOUSE
NC score	0.036166 (rank : 605)	θ value	5.27518 (rank : 373)
Query Neighborhood Hits	438	Target Neighborhood Hits	581	Shared Neighborhood Hits	88
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

X3CL1_HUMAN
NC score	0.035929 (rank : 606)	θ value	4.03905 (rank : 347)
Query Neighborhood Hits	438	Target Neighborhood Hits	152	Shared Neighborhood Hits	25
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

PER1_HUMAN
NC score	0.035619 (rank : 607)	θ value	5.27518 (rank : 372)
Query Neighborhood Hits	438	Target Neighborhood Hits	215	Shared Neighborhood Hits	41
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

IRS2_MOUSE
NC score	0.035060 (rank : 608)	θ value	6.88961 (rank : 393)
Query Neighborhood Hits	438	Target Neighborhood Hits	248	Shared Neighborhood Hits	43
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

CD2L7_HUMAN
NC score	0.034769 (rank : 609)	θ value	0.0193708 (rank : 89)
Query Neighborhood Hits	438	Target Neighborhood Hits	1275	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

PARM1_MOUSE
NC score	0.034271 (rank : 610)	θ value	5.27518 (rank : 370)
Query Neighborhood Hits	438	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

RHG05_MOUSE
NC score	0.034156 (rank : 611)	θ value	3.0926 (rank : 325)
Query Neighborhood Hits	438	Target Neighborhood Hits	165	Shared Neighborhood Hits	19
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

GNDS_HUMAN
NC score	0.032975 (rank : 612)	θ value	0.62314 (rank : 212)
Query Neighborhood Hits	438	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

ANX11_MOUSE
NC score	0.032423 (rank : 613)	θ value	0.62314 (rank : 208)
Query Neighborhood Hits	438	Target Neighborhood Hits	200	Shared Neighborhood Hits	51
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

ZO1_HUMAN
NC score	0.032275 (rank : 614)	θ value	6.88961 (rank : 415)
Query Neighborhood Hits	438	Target Neighborhood Hits	474	Shared Neighborhood Hits	79
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SPEG_HUMAN
NC score	0.031701 (rank : 615)	θ value	6.88961 (rank : 408)
Query Neighborhood Hits	438	Target Neighborhood Hits	1762	Shared Neighborhood Hits	157
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

RHG05_HUMAN
NC score	0.030761 (rank : 616)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	438	Target Neighborhood Hits	158	Shared Neighborhood Hits	18
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

AMELY_HUMAN
NC score	0.030288 (rank : 617)	θ value	5.27518 (rank : 351)
Query Neighborhood Hits	438	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q99218, Q6RWT1	Gene names	AMELY, AMGL, AMGY
Domain Architecture
Description	Amelogenin, Y isoform precursor.

TITIN_HUMAN
NC score	0.029942 (rank : 618)	θ value	0.47712 (rank : 204)
Query Neighborhood Hits	438	Target Neighborhood Hits	2923	Shared Neighborhood Hits	155
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

PLS3_MOUSE
NC score	0.029191 (rank : 619)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	438	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIZ9	Gene names	Plscr3
Domain Architecture
Description	Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3).

DYN1_HUMAN
NC score	0.028707 (rank : 620)	θ value	1.06291 (rank : 237)
Query Neighborhood Hits	438	Target Neighborhood Hits	216	Shared Neighborhood Hits	38
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

ANK3_HUMAN
NC score	0.028638 (rank : 621)	θ value	4.03905 (rank : 332)
Query Neighborhood Hits	438	Target Neighborhood Hits	853	Shared Neighborhood Hits	71
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ESX1L_HUMAN
NC score	0.028213 (rank : 622)	θ value	1.38821 (rank : 261)
Query Neighborhood Hits	438	Target Neighborhood Hits	498	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

K0355_HUMAN
NC score	0.027856 (rank : 623)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	438	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	O15063	Gene names	KIAA0355
Domain Architecture	No domain graphic available
Description	Protein KIAA0355.

ZO1_MOUSE
NC score	0.027616 (rank : 624)	θ value	6.88961 (rank : 416)
Query Neighborhood Hits	438	Target Neighborhood Hits	453	Shared Neighborhood Hits	63
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ARRD1_MOUSE
NC score	0.026681 (rank : 625)	θ value	1.81305 (rank : 279)
Query Neighborhood Hits	438	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

IL2RB_MOUSE
NC score	0.026597 (rank : 626)	θ value	1.38821 (rank : 267)
Query Neighborhood Hits	438	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

MYBPH_HUMAN
NC score	0.025454 (rank : 627)	θ value	0.813845 (rank : 223)
Query Neighborhood Hits	438	Target Neighborhood Hits	256	Shared Neighborhood Hits	13
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

SELO_HUMAN
NC score	0.024950 (rank : 628)	θ value	1.06291 (rank : 248)
Query Neighborhood Hits	438	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BVL4, Q8WUI0	Gene names	SELO
Domain Architecture
Description	Selenoprotein O.

MACF1_MOUSE
NC score	0.024923 (rank : 629)	θ value	0.365318 (rank : 179)
Query Neighborhood Hits	438	Target Neighborhood Hits	1313	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MK07_MOUSE
NC score	0.024738 (rank : 630)	θ value	0.365318 (rank : 181)
Query Neighborhood Hits	438	Target Neighborhood Hits	1054	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

ZN687_HUMAN
NC score	0.024356 (rank : 631)	θ value	0.813845 (rank : 233)
Query Neighborhood Hits	438	Target Neighborhood Hits	1244	Shared Neighborhood Hits	125
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

DYN1_MOUSE
NC score	0.024241 (rank : 632)	θ value	0.813845 (rank : 221)
Query Neighborhood Hits	438	Target Neighborhood Hits	168	Shared Neighborhood Hits	31
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

BCL3_MOUSE
NC score	0.023382 (rank : 633)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	438	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

TREF1_MOUSE
NC score	0.023283 (rank : 634)	θ value	6.88961 (rank : 410)
Query Neighborhood Hits	438	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

FOXJ2_HUMAN
NC score	0.023256 (rank : 635)	θ value	0.365318 (rank : 178)
Query Neighborhood Hits	438	Target Neighborhood Hits	239	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

HCN2_MOUSE
NC score	0.023050 (rank : 636)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	438	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

MAGD1_HUMAN
NC score	0.022918 (rank : 637)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	438	Target Neighborhood Hits	130	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

SAM68_HUMAN
NC score	0.022592 (rank : 638)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	438	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

ATBF1_MOUSE
NC score	0.021993 (rank : 639)	θ value	2.36792 (rank : 294)
Query Neighborhood Hits	438	Target Neighborhood Hits	1841	Shared Neighborhood Hits	108
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

NOTC2_HUMAN
NC score	0.021853 (rank : 640)	θ value	0.0330416 (rank : 100)
Query Neighborhood Hits	438	Target Neighborhood Hits	1113	Shared Neighborhood Hits	111
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MEGF9_HUMAN
NC score	0.021116 (rank : 641)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	438	Target Neighborhood Hits	557	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CF055_HUMAN
NC score	0.020602 (rank : 642)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	438	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP79, Q9H0R2, Q9H3K9, Q9P0Q0	Gene names	C6orf55
Domain Architecture
Description	Protein C6orf55 (Dopamine-responsive protein DRG-1).

ERF_HUMAN
NC score	0.020314 (rank : 643)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	438	Target Neighborhood Hits	162	Shared Neighborhood Hits	27
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

CF055_MOUSE
NC score	0.020205 (rank : 644)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	438	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

ADA12_MOUSE
NC score	0.019156 (rank : 645)	θ value	5.27518 (rank : 350)
Query Neighborhood Hits	438	Target Neighborhood Hits	474	Shared Neighborhood Hits	91
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CUTL1_HUMAN
NC score	0.018935 (rank : 646)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	438	Target Neighborhood Hits	1574	Shared Neighborhood Hits	82
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

NFAT5_MOUSE
NC score	0.018534 (rank : 647)	θ value	5.27518 (rank : 369)
Query Neighborhood Hits	438	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

UBQL4_HUMAN
NC score	0.018343 (rank : 648)	θ value	5.27518 (rank : 379)
Query Neighborhood Hits	438	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

RAVR1_MOUSE
NC score	0.017706 (rank : 649)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	438	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

MAP2_MOUSE
NC score	0.016742 (rank : 650)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	438	Target Neighborhood Hits	342	Shared Neighborhood Hits	33
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

M3K4_MOUSE
NC score	0.016107 (rank : 651)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	438	Target Neighborhood Hits	924	Shared Neighborhood Hits	47
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

CX045_HUMAN
NC score	0.015600 (rank : 652)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	438	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5U8, Q5JXY9	Gene names	CXorf45
Domain Architecture	No domain graphic available
Description	Protein CXorf45.

FA38A_HUMAN
NC score	0.015402 (rank : 653)	θ value	2.36792 (rank : 297)
Query Neighborhood Hits	438	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q92508	Gene names	FAM38A, KIAA0233
Domain Architecture	No domain graphic available
Description	Protein FAM38A.

DUS8_MOUSE
NC score	0.015296 (rank : 654)	θ value	4.03905 (rank : 333)
Query Neighborhood Hits	438	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

MAGI2_MOUSE
NC score	0.014835 (rank : 655)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	438	Target Neighborhood Hits	370	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PABP1_MOUSE
NC score	0.014071 (rank : 656)	θ value	1.38821 (rank : 270)
Query Neighborhood Hits	438	Target Neighborhood Hits	278	Shared Neighborhood Hits	20
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_HUMAN
NC score	0.013980 (rank : 657)	θ value	1.38821 (rank : 269)
Query Neighborhood Hits	438	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PCD15_MOUSE
NC score	0.013799 (rank : 658)	θ value	0.47712 (rank : 200)
Query Neighborhood Hits	438	Target Neighborhood Hits	262	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

K1914_HUMAN
NC score	0.012514 (rank : 659)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	438	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

CAC1A_MOUSE
NC score	0.010723 (rank : 660)	θ value	2.36792 (rank : 296)
Query Neighborhood Hits	438	Target Neighborhood Hits	267	Shared Neighborhood Hits	31
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

REEP3_MOUSE
NC score	0.007844 (rank : 661)	θ value	5.27518 (rank : 375)
Query Neighborhood Hits	438	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KK1, Q9CZM8, Q9D8G3	Gene names	Reep3, D10Ucla1
Domain Architecture	No domain graphic available
Description	Receptor expression-enhancing protein 3.

TRI47_HUMAN
NC score	0.007521 (rank : 662)	θ value	3.0926 (rank : 328)
Query Neighborhood Hits	438	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

VAX1_HUMAN
NC score	0.007006 (rank : 663)	θ value	2.36792 (rank : 308)
Query Neighborhood Hits	438	Target Neighborhood Hits	355	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SQQ9, Q6ZSX0	Gene names	VAX1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

ACON_HUMAN
NC score	0.006319 (rank : 664)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	438	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q99798, O75809	Gene names	ACO2
Domain Architecture
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

DLX5_MOUSE
NC score	0.005617 (rank : 665)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	438	Target Neighborhood Hits	434	Shared Neighborhood Hits	35
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

VAX1_MOUSE
NC score	0.005386 (rank : 666)	θ value	4.03905 (rank : 345)
Query Neighborhood Hits	438	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	Q2NKI2, O88880	Gene names	Vax1
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 1.

WDR7_MOUSE
NC score	0.004736 (rank : 667)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	438	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

MCM4_MOUSE
NC score	0.004551 (rank : 668)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	438	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P49717, O89056	Gene names	Mcm4, Cdc21, Mcmd4
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

ROBO3_MOUSE
NC score	0.004229 (rank : 669)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	438	Target Neighborhood Hits	524	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

EGR2_MOUSE
NC score	0.003417 (rank : 670)	θ value	0.125558 (rank : 140)
Query Neighborhood Hits	438	Target Neighborhood Hits	745	Shared Neighborhood Hits	20
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

K1KB8_MOUSE
NC score	0.001332 (rank : 671)	θ value	1.81305 (rank : 284)
Query Neighborhood Hits	438	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

ABCA7_MOUSE
NC score	0.000911 (rank : 672)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	438	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

K1B16_MOUSE
NC score	0.000391 (rank : 673)	θ value	6.88961 (rank : 397)
Query Neighborhood Hits	438	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

EGFB2_MOUSE
NC score	0.000191 (rank : 674)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	438	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

EGR1_HUMAN
NC score	-0.000887 (rank : 675)	θ value	0.47712 (rank : 192)
Query Neighborhood Hits	438	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

EGR1_MOUSE
NC score	-0.001134 (rank : 676)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	438	Target Neighborhood Hits	816	Shared Neighborhood Hits	44
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

LRTM1_MOUSE
NC score	-0.002414 (rank : 677)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	438	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K377, Q3UVX1	Gene names	Lrrtm1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

ZN628_MOUSE
NC score	-0.006883 (rank : 678)	θ value	4.03905 (rank : 349)
Query Neighborhood Hits	438	Target Neighborhood Hits	815	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).