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Network neighborhood for query Sequence : RIMB2_MOUSE

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RIMB2_MOUSE
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIMB2_HUMAN
θ value	0 (rank : 1)	NC score	0.970108 (rank : 2)
Query Neighborhood Hits	246	Target Neighborhood Hits	263	Shared Neighborhood Hits	172
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	246	Target Neighborhood Hits	246	Shared Neighborhood Hits	246
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB1_MOUSE
θ value	1.58745e-113 (rank : 3)	NC score	0.498115 (rank : 4)
Query Neighborhood Hits	246	Target Neighborhood Hits	1376	Shared Neighborhood Hits	169
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_HUMAN
θ value	3.00075e-104 (rank : 4)	NC score	0.562752 (rank : 3)
Query Neighborhood Hits	246	Target Neighborhood Hits	1479	Shared Neighborhood Hits	169
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CD2AP_MOUSE
θ value	1.9326e-10 (rank : 5)	NC score	0.477154 (rank : 5)
Query Neighborhood Hits	246	Target Neighborhood Hits	336	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2AP_HUMAN
θ value	1.25267e-09 (rank : 6)	NC score	0.473106 (rank : 6)
Query Neighborhood Hits	246	Target Neighborhood Hits	315	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

SH3K1_MOUSE
θ value	1.80886e-08 (rank : 7)	NC score	0.454335 (rank : 8)
Query Neighborhood Hits	246	Target Neighborhood Hits	332	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SH3K1_HUMAN
θ value	2.36244e-08 (rank : 8)	NC score	0.457947 (rank : 7)
Query Neighborhood Hits	246	Target Neighborhood Hits	341	Shared Neighborhood Hits	118
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

PTPRD_HUMAN
θ value	1.17247e-07 (rank : 9)	NC score	0.174049 (rank : 111)
Query Neighborhood Hits	246	Target Neighborhood Hits	485	Shared Neighborhood Hits	55
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRS_HUMAN
θ value	1.99992e-07 (rank : 10)	NC score	0.178075 (rank : 108)
Query Neighborhood Hits	246	Target Neighborhood Hits	472	Shared Neighborhood Hits	55
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRF_HUMAN
θ value	5.81887e-07 (rank : 11)	NC score	0.165616 (rank : 128)
Query Neighborhood Hits	246	Target Neighborhood Hits	489	Shared Neighborhood Hits	53
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

DNMBP_HUMAN
θ value	1.69304e-06 (rank : 12)	NC score	0.345314 (rank : 21)
Query Neighborhood Hits	246	Target Neighborhood Hits	413	Shared Neighborhood Hits	112
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PTPRD_MOUSE
θ value	6.43352e-06 (rank : 13)	NC score	0.169609 (rank : 120)
Query Neighborhood Hits	246	Target Neighborhood Hits	491	Shared Neighborhood Hits	56
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FINC_MOUSE
θ value	8.40245e-06 (rank : 14)	NC score	0.248937 (rank : 71)
Query Neighborhood Hits	246	Target Neighborhood Hits	309	Shared Neighborhood Hits	58
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

SDK2_HUMAN
θ value	2.44474e-05 (rank : 15)	NC score	0.188449 (rank : 103)
Query Neighborhood Hits	246	Target Neighborhood Hits	495	Shared Neighborhood Hits	56
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TENR_MOUSE
θ value	2.44474e-05 (rank : 16)	NC score	0.153572 (rank : 137)
Query Neighborhood Hits	246	Target Neighborhood Hits	531	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

PACN1_HUMAN
θ value	3.19293e-05 (rank : 17)	NC score	0.345970 (rank : 19)
Query Neighborhood Hits	246	Target Neighborhood Hits	320	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	3.19293e-05 (rank : 18)	NC score	0.345825 (rank : 20)
Query Neighborhood Hits	246	Target Neighborhood Hits	283	Shared Neighborhood Hits	108
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

TENR_HUMAN
θ value	3.19293e-05 (rank : 19)	NC score	0.156390 (rank : 133)
Query Neighborhood Hits	246	Target Neighborhood Hits	526	Shared Neighborhood Hits	52
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

FINC_HUMAN
θ value	5.44631e-05 (rank : 20)	NC score	0.240984 (rank : 75)
Query Neighborhood Hits	246	Target Neighborhood Hits	302	Shared Neighborhood Hits	55
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

DNMBP_MOUSE
θ value	7.1131e-05 (rank : 21)	NC score	0.336307 (rank : 24)
Query Neighborhood Hits	246	Target Neighborhood Hits	435	Shared Neighborhood Hits	116
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SH3G1_HUMAN
θ value	7.1131e-05 (rank : 22)	NC score	0.375375 (rank : 12)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	129
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

AHI1_MOUSE
θ value	9.29e-05 (rank : 23)	NC score	0.241652 (rank : 74)
Query Neighborhood Hits	246	Target Neighborhood Hits	496	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ITSN1_HUMAN
θ value	0.000121331 (rank : 24)	NC score	0.254738 (rank : 64)
Query Neighborhood Hits	246	Target Neighborhood Hits	1757	Shared Neighborhood Hits	161
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SH3G2_MOUSE
θ value	0.000121331 (rank : 25)	NC score	0.385642 (rank : 10)
Query Neighborhood Hits	246	Target Neighborhood Hits	319	Shared Neighborhood Hits	125
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

ITSN2_HUMAN
θ value	0.00020696 (rank : 26)	NC score	0.263938 (rank : 58)
Query Neighborhood Hits	246	Target Neighborhood Hits	1173	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SH3G2_HUMAN
θ value	0.00020696 (rank : 27)	NC score	0.384415 (rank : 11)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	128
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G3_MOUSE
θ value	0.00035302 (rank : 28)	NC score	0.386478 (rank : 9)
Query Neighborhood Hits	246	Target Neighborhood Hits	236	Shared Neighborhood Hits	121
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

ITSN1_MOUSE
θ value	0.000461057 (rank : 29)	NC score	0.253647 (rank : 67)
Query Neighborhood Hits	246	Target Neighborhood Hits	1669	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ABI2_HUMAN
θ value	0.000602161 (rank : 30)	NC score	0.350207 (rank : 18)
Query Neighborhood Hits	246	Target Neighborhood Hits	350	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	0.000602161 (rank : 31)	NC score	0.356225 (rank : 16)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	105
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

PACN2_HUMAN
θ value	0.000602161 (rank : 32)	NC score	0.336680 (rank : 23)
Query Neighborhood Hits	246	Target Neighborhood Hits	339	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

AHI1_HUMAN
θ value	0.000786445 (rank : 33)	NC score	0.239686 (rank : 78)
Query Neighborhood Hits	246	Target Neighborhood Hits	537	Shared Neighborhood Hits	107
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

VAV3_HUMAN
θ value	0.000786445 (rank : 34)	NC score	0.243137 (rank : 73)
Query Neighborhood Hits	246	Target Neighborhood Hits	398	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

PPIP1_HUMAN
θ value	0.00102713 (rank : 35)	NC score	0.330443 (rank : 26)
Query Neighborhood Hits	246	Target Neighborhood Hits	389	Shared Neighborhood Hits	123
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PPIP1_MOUSE
θ value	0.00102713 (rank : 36)	NC score	0.337541 (rank : 22)
Query Neighborhood Hits	246	Target Neighborhood Hits	377	Shared Neighborhood Hits	122
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SH3G3_HUMAN
θ value	0.00102713 (rank : 37)	NC score	0.371189 (rank : 13)
Query Neighborhood Hits	246	Target Neighborhood Hits	222	Shared Neighborhood Hits	119
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

NCF1_HUMAN
θ value	0.00134147 (rank : 38)	NC score	0.299714 (rank : 42)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	95
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

STAM2_MOUSE
θ value	0.00134147 (rank : 39)	NC score	0.307260 (rank : 40)
Query Neighborhood Hits	246	Target Neighborhood Hits	285	Shared Neighborhood Hits	113
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SH3G1_MOUSE
θ value	0.00175202 (rank : 40)	NC score	0.367647 (rank : 14)
Query Neighborhood Hits	246	Target Neighborhood Hits	291	Shared Neighborhood Hits	123
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

TENA_MOUSE
θ value	0.00175202 (rank : 41)	NC score	0.112312 (rank : 211)
Query Neighborhood Hits	246	Target Neighborhood Hits	596	Shared Neighborhood Hits	50
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TITIN_HUMAN
θ value	0.00175202 (rank : 42)	NC score	0.094109 (rank : 244)
Query Neighborhood Hits	246	Target Neighborhood Hits	2923	Shared Neighborhood Hits	115
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

GRB2_HUMAN
θ value	0.00228821 (rank : 43)	NC score	0.323746 (rank : 29)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	116
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.00228821 (rank : 44)	NC score	0.323878 (rank : 28)
Query Neighborhood Hits	246	Target Neighborhood Hits	312	Shared Neighborhood Hits	116
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

ITSN2_MOUSE
θ value	0.00228821 (rank : 45)	NC score	0.253919 (rank : 65)
Query Neighborhood Hits	246	Target Neighborhood Hits	1371	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PACN2_MOUSE
θ value	0.00228821 (rank : 46)	NC score	0.321851 (rank : 30)
Query Neighborhood Hits	246	Target Neighborhood Hits	382	Shared Neighborhood Hits	117
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

ROBO3_MOUSE
θ value	0.00228821 (rank : 47)	NC score	0.142850 (rank : 145)
Query Neighborhood Hits	246	Target Neighborhood Hits	524	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

VAV_HUMAN
θ value	0.00228821 (rank : 48)	NC score	0.268731 (rank : 56)
Query Neighborhood Hits	246	Target Neighborhood Hits	452	Shared Neighborhood Hits	110
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	0.00228821 (rank : 49)	NC score	0.269983 (rank : 54)
Query Neighborhood Hits	246	Target Neighborhood Hits	430	Shared Neighborhood Hits	112
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VINEX_HUMAN
θ value	0.00228821 (rank : 50)	NC score	0.362962 (rank : 15)
Query Neighborhood Hits	246	Target Neighborhood Hits	270	Shared Neighborhood Hits	110
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ARHG6_HUMAN
θ value	0.00298849 (rank : 51)	NC score	0.310738 (rank : 35)
Query Neighborhood Hits	246	Target Neighborhood Hits	376	Shared Neighborhood Hits	119
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	0.00298849 (rank : 52)	NC score	0.310634 (rank : 36)
Query Neighborhood Hits	246	Target Neighborhood Hits	394	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

VAV3_MOUSE
θ value	0.00298849 (rank : 53)	NC score	0.236291 (rank : 81)
Query Neighborhood Hits	246	Target Neighborhood Hits	404	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

EM55_HUMAN
θ value	0.00390308 (rank : 54)	NC score	0.177372 (rank : 109)
Query Neighborhood Hits	246	Target Neighborhood Hits	228	Shared Neighborhood Hits	74
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

NEO1_MOUSE
θ value	0.00390308 (rank : 55)	NC score	0.172125 (rank : 116)
Query Neighborhood Hits	246	Target Neighborhood Hits	523	Shared Neighborhood Hits	52
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

VINEX_MOUSE
θ value	0.00390308 (rank : 56)	NC score	0.355514 (rank : 17)
Query Neighborhood Hits	246	Target Neighborhood Hits	286	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ARHG7_HUMAN
θ value	0.00665767 (rank : 57)	NC score	0.302867 (rank : 41)
Query Neighborhood Hits	246	Target Neighborhood Hits	347	Shared Neighborhood Hits	117
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

BTK_HUMAN
θ value	0.00665767 (rank : 58)	NC score	0.080611 (rank : 291)
Query Neighborhood Hits	246	Target Neighborhood Hits	1026	Shared Neighborhood Hits	113
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

EM55_MOUSE
θ value	0.00665767 (rank : 59)	NC score	0.173480 (rank : 112)
Query Neighborhood Hits	246	Target Neighborhood Hits	221	Shared Neighborhood Hits	74
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NEO1_HUMAN
θ value	0.00665767 (rank : 60)	NC score	0.169935 (rank : 119)
Query Neighborhood Hits	246	Target Neighborhood Hits	530	Shared Neighborhood Hits	52
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

SDK2_MOUSE
θ value	0.00665767 (rank : 61)	NC score	0.183282 (rank : 106)
Query Neighborhood Hits	246	Target Neighborhood Hits	480	Shared Neighborhood Hits	56
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

COCA1_HUMAN
θ value	0.00869519 (rank : 62)	NC score	0.153716 (rank : 136)
Query Neighborhood Hits	246	Target Neighborhood Hits	458	Shared Neighborhood Hits	54
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CP250_HUMAN
θ value	0.00869519 (rank : 63)	NC score	0.078966 (rank : 301)
Query Neighborhood Hits	246	Target Neighborhood Hits	1805	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GRAP_MOUSE
θ value	0.00869519 (rank : 64)	NC score	0.297490 (rank : 43)
Query Neighborhood Hits	246	Target Neighborhood Hits	309	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

MPP3_MOUSE
θ value	0.00869519 (rank : 65)	NC score	0.114108 (rank : 208)
Query Neighborhood Hits	246	Target Neighborhood Hits	165	Shared Neighborhood Hits	32
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MYO1F_HUMAN
θ value	0.00869519 (rank : 66)	NC score	0.150783 (rank : 139)
Query Neighborhood Hits	246	Target Neighborhood Hits	275	Shared Neighborhood Hits	113
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

NCF1_MOUSE
θ value	0.00869519 (rank : 67)	NC score	0.294324 (rank : 45)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	102
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

ROBO1_HUMAN
θ value	0.00869519 (rank : 68)	NC score	0.144200 (rank : 143)
Query Neighborhood Hits	246	Target Neighborhood Hits	529	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ING3_MOUSE
θ value	0.0113563 (rank : 69)	NC score	0.066785 (rank : 389)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

NCK2_HUMAN
θ value	0.0113563 (rank : 70)	NC score	0.289985 (rank : 49)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	106
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

REST_HUMAN
θ value	0.0113563 (rank : 71)	NC score	0.071360 (rank : 341)
Query Neighborhood Hits	246	Target Neighborhood Hits	1605	Shared Neighborhood Hits	72
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ABI1_HUMAN
θ value	0.0148317 (rank : 72)	NC score	0.318582 (rank : 31)
Query Neighborhood Hits	246	Target Neighborhood Hits	257	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

BTK_MOUSE
θ value	0.0148317 (rank : 73)	NC score	0.077648 (rank : 307)
Query Neighborhood Hits	246	Target Neighborhood Hits	1017	Shared Neighborhood Hits	110
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

GRAP_HUMAN
θ value	0.0148317 (rank : 74)	NC score	0.285600 (rank : 51)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	113
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

NCK1_HUMAN
θ value	0.0148317 (rank : 75)	NC score	0.293534 (rank : 47)
Query Neighborhood Hits	246	Target Neighborhood Hits	312	Shared Neighborhood Hits	107
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

CP250_MOUSE
θ value	0.0193708 (rank : 76)	NC score	0.081081 (rank : 289)
Query Neighborhood Hits	246	Target Neighborhood Hits	1583	Shared Neighborhood Hits	68
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

SDK1_HUMAN
θ value	0.0193708 (rank : 77)	NC score	0.176569 (rank : 110)
Query Neighborhood Hits	246	Target Neighborhood Hits	511	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

MPP3_HUMAN
θ value	0.0252991 (rank : 78)	NC score	0.113116 (rank : 209)
Query Neighborhood Hits	246	Target Neighborhood Hits	171	Shared Neighborhood Hits	33
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

OSTF1_HUMAN
θ value	0.0252991 (rank : 79)	NC score	0.267684 (rank : 57)
Query Neighborhood Hits	246	Target Neighborhood Hits	466	Shared Neighborhood Hits	112
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

SNX9_HUMAN
θ value	0.0252991 (rank : 80)	NC score	0.211507 (rank : 89)
Query Neighborhood Hits	246	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

STAM1_HUMAN
θ value	0.0252991 (rank : 81)	NC score	0.309654 (rank : 38)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	118
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	0.0252991 (rank : 82)	NC score	0.293828 (rank : 46)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	118
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

ASPP2_HUMAN
θ value	0.0330416 (rank : 83)	NC score	0.142986 (rank : 144)
Query Neighborhood Hits	246	Target Neighborhood Hits	1156	Shared Neighborhood Hits	135
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CNTN3_HUMAN
θ value	0.0330416 (rank : 84)	NC score	0.133895 (rank : 161)
Query Neighborhood Hits	246	Target Neighborhood Hits	455	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

COCA1_MOUSE
θ value	0.0330416 (rank : 85)	NC score	0.161490 (rank : 131)
Query Neighborhood Hits	246	Target Neighborhood Hits	467	Shared Neighborhood Hits	57
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

DCC_HUMAN
θ value	0.0330416 (rank : 86)	NC score	0.164959 (rank : 129)
Query Neighborhood Hits	246	Target Neighborhood Hits	583	Shared Neighborhood Hits	54
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	0.0330416 (rank : 87)	NC score	0.159933 (rank : 132)
Query Neighborhood Hits	246	Target Neighborhood Hits	896	Shared Neighborhood Hits	62
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

FGR_HUMAN
θ value	0.0330416 (rank : 88)	NC score	0.090790 (rank : 249)
Query Neighborhood Hits	246	Target Neighborhood Hits	1067	Shared Neighborhood Hits	120
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

M3KL4_HUMAN
θ value	0.0330416 (rank : 89)	NC score	0.092348 (rank : 247)
Query Neighborhood Hits	246	Target Neighborhood Hits	1087	Shared Neighborhood Hits	123
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

OSTF1_MOUSE
θ value	0.0330416 (rank : 90)	NC score	0.258229 (rank : 60)
Query Neighborhood Hits	246	Target Neighborhood Hits	467	Shared Neighborhood Hits	114
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

SHAN1_HUMAN
θ value	0.0330416 (rank : 91)	NC score	0.123707 (rank : 183)
Query Neighborhood Hits	246	Target Neighborhood Hits	1041	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_MOUSE
θ value	0.0330416 (rank : 92)	NC score	0.171419 (rank : 117)
Query Neighborhood Hits	246	Target Neighborhood Hits	446	Shared Neighborhood Hits	80
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SNX9_MOUSE
θ value	0.0330416 (rank : 93)	NC score	0.196017 (rank : 98)
Query Neighborhood Hits	246	Target Neighborhood Hits	141	Shared Neighborhood Hits	69
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

STAM1_MOUSE
θ value	0.0330416 (rank : 94)	NC score	0.308185 (rank : 39)
Query Neighborhood Hits	246	Target Neighborhood Hits	273	Shared Neighborhood Hits	119
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

PACN3_HUMAN
θ value	0.0431538 (rank : 95)	NC score	0.313166 (rank : 33)
Query Neighborhood Hits	246	Target Neighborhood Hits	385	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	0.0431538 (rank : 96)	NC score	0.310116 (rank : 37)
Query Neighborhood Hits	246	Target Neighborhood Hits	380	Shared Neighborhood Hits	114
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

RHG26_HUMAN
θ value	0.0431538 (rank : 97)	NC score	0.173101 (rank : 114)
Query Neighborhood Hits	246	Target Neighborhood Hits	281	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

ROBO1_MOUSE
θ value	0.0431538 (rank : 98)	NC score	0.141136 (rank : 146)
Query Neighborhood Hits	246	Target Neighborhood Hits	559	Shared Neighborhood Hits	53
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

SDK1_MOUSE
θ value	0.0431538 (rank : 99)	NC score	0.173412 (rank : 113)
Query Neighborhood Hits	246	Target Neighborhood Hits	495	Shared Neighborhood Hits	55
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ARHG7_MOUSE
θ value	0.0563607 (rank : 100)	NC score	0.296890 (rank : 44)
Query Neighborhood Hits	246	Target Neighborhood Hits	396	Shared Neighborhood Hits	117
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CSK_HUMAN
θ value	0.0563607 (rank : 101)	NC score	0.063393 (rank : 427)
Query Neighborhood Hits	246	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	0.0563607 (rank : 102)	NC score	0.063445 (rank : 425)
Query Neighborhood Hits	246	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

FGR_MOUSE
θ value	0.0563607 (rank : 103)	NC score	0.081712 (rank : 285)
Query Neighborhood Hits	246	Target Neighborhood Hits	1069	Shared Neighborhood Hits	117
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ING3_HUMAN
θ value	0.0563607 (rank : 104)	NC score	0.061884 (rank : 458)
Query Neighborhood Hits	246	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

MYO1F_MOUSE
θ value	0.0563607 (rank : 105)	NC score	0.147899 (rank : 141)
Query Neighborhood Hits	246	Target Neighborhood Hits	262	Shared Neighborhood Hits	115
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

PTPRB_HUMAN
θ value	0.0563607 (rank : 106)	NC score	0.119700 (rank : 191)
Query Neighborhood Hits	246	Target Neighborhood Hits	242	Shared Neighborhood Hits	47
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

SHLB1_HUMAN
θ value	0.0563607 (rank : 107)	NC score	0.229422 (rank : 86)
Query Neighborhood Hits	246	Target Neighborhood Hits	96	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SRBS1_HUMAN
θ value	0.0563607 (rank : 108)	NC score	0.328376 (rank : 27)
Query Neighborhood Hits	246	Target Neighborhood Hits	396	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ABI1_MOUSE
θ value	0.0736092 (rank : 109)	NC score	0.316442 (rank : 32)
Query Neighborhood Hits	246	Target Neighborhood Hits	246	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

SHLB1_MOUSE
θ value	0.0736092 (rank : 110)	NC score	0.232795 (rank : 84)
Query Neighborhood Hits	246	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SRBS1_MOUSE
θ value	0.0736092 (rank : 111)	NC score	0.331735 (rank : 25)
Query Neighborhood Hits	246	Target Neighborhood Hits	409	Shared Neighborhood Hits	114
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CT075_HUMAN
θ value	0.0961366 (rank : 112)	NC score	0.076132 (rank : 320)
Query Neighborhood Hits	246	Target Neighborhood Hits	387	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

DSCL1_HUMAN
θ value	0.0961366 (rank : 113)	NC score	0.154042 (rank : 135)
Query Neighborhood Hits	246	Target Neighborhood Hits	589	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

MPP2_MOUSE
θ value	0.0961366 (rank : 114)	NC score	0.133688 (rank : 162)
Query Neighborhood Hits	246	Target Neighborhood Hits	189	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MYH11_MOUSE
θ value	0.0961366 (rank : 115)	NC score	0.058168 (rank : 520)
Query Neighborhood Hits	246	Target Neighborhood Hits	1777	Shared Neighborhood Hits	77
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_HUMAN
θ value	0.125558 (rank : 116)	NC score	0.059053 (rank : 508)
Query Neighborhood Hits	246	Target Neighborhood Hits	1806	Shared Neighborhood Hits	81
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CSKP_HUMAN
θ value	0.163984 (rank : 117)	NC score	0.062208 (rank : 447)
Query Neighborhood Hits	246	Target Neighborhood Hits	1022	Shared Neighborhood Hits	87
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

ROBO2_HUMAN
θ value	0.163984 (rank : 118)	NC score	0.138745 (rank : 153)
Query Neighborhood Hits	246	Target Neighborhood Hits	479	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_MOUSE
θ value	0.163984 (rank : 119)	NC score	0.138885 (rank : 152)
Query Neighborhood Hits	246	Target Neighborhood Hits	504	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SRC8_HUMAN
θ value	0.163984 (rank : 120)	NC score	0.292885 (rank : 48)
Query Neighborhood Hits	246	Target Neighborhood Hits	269	Shared Neighborhood Hits	113
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

USH2A_MOUSE
θ value	0.163984 (rank : 121)	NC score	0.112020 (rank : 212)
Query Neighborhood Hits	246	Target Neighborhood Hits	626	Shared Neighborhood Hits	55
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

YETS2_HUMAN
θ value	0.163984 (rank : 122)	NC score	0.050998 (rank : 705)
Query Neighborhood Hits	246	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

CRK_HUMAN
θ value	0.21417 (rank : 123)	NC score	0.263327 (rank : 59)
Query Neighborhood Hits	246	Target Neighborhood Hits	308	Shared Neighborhood Hits	112
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	0.21417 (rank : 124)	NC score	0.269316 (rank : 55)
Query Neighborhood Hits	246	Target Neighborhood Hits	314	Shared Neighborhood Hits	112
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GCC2_HUMAN
θ value	0.21417 (rank : 125)	NC score	0.066004 (rank : 397)
Query Neighborhood Hits	246	Target Neighborhood Hits	1558	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.21417 (rank : 126)	NC score	0.065502 (rank : 403)
Query Neighborhood Hits	246	Target Neighborhood Hits	1559	Shared Neighborhood Hits	72
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SRC8_MOUSE
θ value	0.21417 (rank : 127)	NC score	0.286677 (rank : 50)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	112
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SYCP1_HUMAN
θ value	0.21417 (rank : 128)	NC score	0.061379 (rank : 465)
Query Neighborhood Hits	246	Target Neighborhood Hits	1313	Shared Neighborhood Hits	59
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

VAV2_MOUSE
θ value	0.21417 (rank : 129)	NC score	0.240056 (rank : 77)
Query Neighborhood Hits	246	Target Neighborhood Hits	456	Shared Neighborhood Hits	115
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

BCAR1_HUMAN
θ value	0.279714 (rank : 130)	NC score	0.215437 (rank : 87)
Query Neighborhood Hits	246	Target Neighborhood Hits	554	Shared Neighborhood Hits	104
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CNTN4_MOUSE
θ value	0.279714 (rank : 131)	NC score	0.126010 (rank : 173)
Query Neighborhood Hits	246	Target Neighborhood Hits	445	Shared Neighborhood Hits	53
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

GRAP2_HUMAN
θ value	0.279714 (rank : 132)	NC score	0.275220 (rank : 53)
Query Neighborhood Hits	246	Target Neighborhood Hits	304	Shared Neighborhood Hits	111
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

M3K11_HUMAN
θ value	0.279714 (rank : 133)	NC score	0.087455 (rank : 265)
Query Neighborhood Hits	246	Target Neighborhood Hits	1136	Shared Neighborhood Hits	122
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MPP2_HUMAN
θ value	0.279714 (rank : 134)	NC score	0.128554 (rank : 170)
Query Neighborhood Hits	246	Target Neighborhood Hits	173	Shared Neighborhood Hits	57
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

PCNT_HUMAN
θ value	0.279714 (rank : 135)	NC score	0.072488 (rank : 337)
Query Neighborhood Hits	246	Target Neighborhood Hits	1551	Shared Neighborhood Hits	78
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

VAV2_HUMAN
θ value	0.279714 (rank : 136)	NC score	0.238130 (rank : 79)
Query Neighborhood Hits	246	Target Neighborhood Hits	453	Shared Neighborhood Hits	114
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

KIF14_HUMAN
θ value	0.365318 (rank : 137)	NC score	0.035083 (rank : 751)
Query Neighborhood Hits	246	Target Neighborhood Hits	732	Shared Neighborhood Hits	44
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

SRGP2_HUMAN
θ value	0.365318 (rank : 138)	NC score	0.137214 (rank : 155)
Query Neighborhood Hits	246	Target Neighborhood Hits	331	Shared Neighborhood Hits	99
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

YTHD2_HUMAN
θ value	0.365318 (rank : 139)	NC score	0.023715 (rank : 757)
Query Neighborhood Hits	246	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

CYTSA_HUMAN
θ value	0.47712 (rank : 140)	NC score	0.055788 (rank : 589)
Query Neighborhood Hits	246	Target Neighborhood Hits	1138	Shared Neighborhood Hits	63
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

EFS_HUMAN
θ value	0.47712 (rank : 141)	NC score	0.230049 (rank : 85)
Query Neighborhood Hits	246	Target Neighborhood Hits	348	Shared Neighborhood Hits	101
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

GRAP2_MOUSE
θ value	0.47712 (rank : 142)	NC score	0.277968 (rank : 52)
Query Neighborhood Hits	246	Target Neighborhood Hits	297	Shared Neighborhood Hits	110
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

NCF2_HUMAN
θ value	0.47712 (rank : 143)	NC score	0.311831 (rank : 34)
Query Neighborhood Hits	246	Target Neighborhood Hits	229	Shared Neighborhood Hits	97
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

CNTN3_MOUSE
θ value	0.62314 (rank : 144)	NC score	0.130320 (rank : 168)
Query Neighborhood Hits	246	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CT032_HUMAN
θ value	0.62314 (rank : 145)	NC score	0.247518 (rank : 72)
Query Neighborhood Hits	246	Target Neighborhood Hits	235	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

LRRK2_MOUSE
θ value	0.62314 (rank : 146)	NC score	0.016931 (rank : 766)
Query Neighborhood Hits	246	Target Neighborhood Hits	1359	Shared Neighborhood Hits	28
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

MPP6_HUMAN
θ value	0.62314 (rank : 147)	NC score	0.139833 (rank : 150)
Query Neighborhood Hits	246	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MYH9_MOUSE
θ value	0.62314 (rank : 148)	NC score	0.058936 (rank : 510)
Query Neighborhood Hits	246	Target Neighborhood Hits	1829	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SRGP2_MOUSE
θ value	0.62314 (rank : 149)	NC score	0.137875 (rank : 154)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	102
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

T53I2_MOUSE
θ value	0.62314 (rank : 150)	NC score	0.036540 (rank : 748)
Query Neighborhood Hits	246	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFU8, Q711P5, Q8CHM4	Gene names	Tp53inp2, Dor, Trp53inp2
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity- regulated protein).

EFS_MOUSE
θ value	0.813845 (rank : 151)	NC score	0.240133 (rank : 76)
Query Neighborhood Hits	246	Target Neighborhood Hits	389	Shared Neighborhood Hits	100
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

MPP6_MOUSE
θ value	0.813845 (rank : 152)	NC score	0.135682 (rank : 156)
Query Neighborhood Hits	246	Target Neighborhood Hits	187	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

ROBO3_HUMAN
θ value	0.813845 (rank : 153)	NC score	0.131378 (rank : 165)
Query Neighborhood Hits	246	Target Neighborhood Hits	570	Shared Neighborhood Hits	54
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

SHLB2_HUMAN
θ value	0.813845 (rank : 154)	NC score	0.169314 (rank : 121)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	0.813845 (rank : 155)	NC score	0.169284 (rank : 122)
Query Neighborhood Hits	246	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

TENA_HUMAN
θ value	0.813845 (rank : 156)	NC score	0.104507 (rank : 222)
Query Neighborhood Hits	246	Target Neighborhood Hits	631	Shared Neighborhood Hits	52
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TEX9_HUMAN
θ value	0.813845 (rank : 157)	NC score	0.047213 (rank : 733)
Query Neighborhood Hits	246	Target Neighborhood Hits	541	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

BCAR1_MOUSE
θ value	1.06291 (rank : 158)	NC score	0.215348 (rank : 88)
Query Neighborhood Hits	246	Target Neighborhood Hits	438	Shared Neighborhood Hits	103
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CNTN4_HUMAN
θ value	1.06291 (rank : 159)	NC score	0.124170 (rank : 180)
Query Neighborhood Hits	246	Target Neighborhood Hits	449	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

ROBO4_HUMAN
θ value	1.06291 (rank : 160)	NC score	0.131048 (rank : 166)
Query Neighborhood Hits	246	Target Neighborhood Hits	364	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

SRC_HUMAN
θ value	1.06291 (rank : 161)	NC score	0.081237 (rank : 288)
Query Neighborhood Hits	246	Target Neighborhood Hits	1058	Shared Neighborhood Hits	117
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

STXB4_HUMAN
θ value	1.06291 (rank : 162)	NC score	0.042189 (rank : 741)
Query Neighborhood Hits	246	Target Neighborhood Hits	616	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TIE2_HUMAN
θ value	1.06291 (rank : 163)	NC score	0.052815 (rank : 658)
Query Neighborhood Hits	246	Target Neighborhood Hits	1192	Shared Neighborhood Hits	67
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

CYTSA_MOUSE
θ value	1.38821 (rank : 164)	NC score	0.054220 (rank : 624)
Query Neighborhood Hits	246	Target Neighborhood Hits	1104	Shared Neighborhood Hits	62
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

GLDN_MOUSE
θ value	1.38821 (rank : 165)	NC score	0.014031 (rank : 769)
Query Neighborhood Hits	246	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

MPP4_MOUSE
θ value	1.38821 (rank : 166)	NC score	0.107618 (rank : 218)
Query Neighborhood Hits	246	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

PLCG2_HUMAN
θ value	1.38821 (rank : 167)	NC score	0.171113 (rank : 118)
Query Neighborhood Hits	246	Target Neighborhood Hits	280	Shared Neighborhood Hits	93
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

RUFY2_HUMAN
θ value	1.38821 (rank : 168)	NC score	0.055339 (rank : 596)
Query Neighborhood Hits	246	Target Neighborhood Hits	1208	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

TENN_MOUSE
θ value	1.38821 (rank : 169)	NC score	0.140334 (rank : 147)
Query Neighborhood Hits	246	Target Neighborhood Hits	484	Shared Neighborhood Hits	52
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

YETS2_MOUSE
θ value	1.38821 (rank : 170)	NC score	0.039707 (rank : 745)
Query Neighborhood Hits	246	Target Neighborhood Hits	278	Shared Neighborhood Hits	12
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

CCD21_HUMAN
θ value	1.81305 (rank : 171)	NC score	0.068989 (rank : 370)
Query Neighborhood Hits	246	Target Neighborhood Hits	1228	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CS007_MOUSE
θ value	1.81305 (rank : 172)	NC score	0.017584 (rank : 765)
Query Neighborhood Hits	246	Target Neighborhood Hits	464	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DBF4_MOUSE
θ value	1.81305 (rank : 173)	NC score	0.024107 (rank : 756)
Query Neighborhood Hits	246	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ41, Q3TQP4, Q3V1K2, Q6NSQ1, Q9CXF2	Gene names	Dbf4
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (MuDBF4).

GOGA1_HUMAN
θ value	1.81305 (rank : 174)	NC score	0.067442 (rank : 382)
Query Neighborhood Hits	246	Target Neighborhood Hits	1222	Shared Neighborhood Hits	58
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MBRL_HUMAN
θ value	1.81305 (rank : 175)	NC score	0.024333 (rank : 755)
Query Neighborhood Hits	246	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q4ZIN3, O60392, Q8NF79, Q96H30	Gene names	C19orf6
Domain Architecture	No domain graphic available
Description	Membralin.

MYPC3_HUMAN
θ value	1.81305 (rank : 176)	NC score	0.116342 (rank : 199)
Query Neighborhood Hits	246	Target Neighborhood Hits	318	Shared Neighborhood Hits	51
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MYPC3_MOUSE
θ value	1.81305 (rank : 177)	NC score	0.116946 (rank : 197)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NASP_HUMAN
θ value	1.81305 (rank : 178)	NC score	0.028921 (rank : 752)
Query Neighborhood Hits	246	Target Neighborhood Hits	709	Shared Neighborhood Hits	31
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

TIE2_MOUSE
θ value	1.81305 (rank : 179)	NC score	0.051536 (rank : 689)
Query Neighborhood Hits	246	Target Neighborhood Hits	1204	Shared Neighborhood Hits	67
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

USH2A_HUMAN
θ value	1.81305 (rank : 180)	NC score	0.119022 (rank : 192)
Query Neighborhood Hits	246	Target Neighborhood Hits	600	Shared Neighborhood Hits	55
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

CE290_HUMAN
θ value	2.36792 (rank : 181)	NC score	0.070418 (rank : 348)
Query Neighborhood Hits	246	Target Neighborhood Hits	1553	Shared Neighborhood Hits	65
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CNTN6_MOUSE
θ value	2.36792 (rank : 182)	NC score	0.123434 (rank : 184)
Query Neighborhood Hits	246	Target Neighborhood Hits	429	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

GLE1_HUMAN
θ value	2.36792 (rank : 183)	NC score	0.090084 (rank : 251)
Query Neighborhood Hits	246	Target Neighborhood Hits	445	Shared Neighborhood Hits	37
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

JIP4_HUMAN
θ value	2.36792 (rank : 184)	NC score	0.045944 (rank : 736)
Query Neighborhood Hits	246	Target Neighborhood Hits	585	Shared Neighborhood Hits	40
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

JIP4_MOUSE
θ value	2.36792 (rank : 185)	NC score	0.043367 (rank : 739)
Query Neighborhood Hits	246	Target Neighborhood Hits	593	Shared Neighborhood Hits	39
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

LZTS2_MOUSE
θ value	2.36792 (rank : 186)	NC score	0.073065 (rank : 331)
Query Neighborhood Hits	246	Target Neighborhood Hits	423	Shared Neighborhood Hits	34
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

MILK1_MOUSE
θ value	2.36792 (rank : 187)	NC score	0.039854 (rank : 744)
Query Neighborhood Hits	246	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NACAM_MOUSE
θ value	2.36792 (rank : 188)	NC score	0.044309 (rank : 737)
Query Neighborhood Hits	246	Target Neighborhood Hits	1866	Shared Neighborhood Hits	62
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NR1H4_MOUSE
θ value	2.36792 (rank : 189)	NC score	0.006683 (rank : 778)
Query Neighborhood Hits	246	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

YES_HUMAN
θ value	2.36792 (rank : 190)	NC score	0.079643 (rank : 298)
Query Neighborhood Hits	246	Target Neighborhood Hits	1059	Shared Neighborhood Hits	120
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	2.36792 (rank : 191)	NC score	0.080056 (rank : 296)
Query Neighborhood Hits	246	Target Neighborhood Hits	1052	Shared Neighborhood Hits	119
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

CASL_MOUSE
θ value	3.0926 (rank : 192)	NC score	0.206910 (rank : 90)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	100
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CCHCR_HUMAN
θ value	3.0926 (rank : 193)	NC score	0.068269 (rank : 375)
Query Neighborhood Hits	246	Target Neighborhood Hits	717	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

COEA1_HUMAN
θ value	3.0926 (rank : 194)	NC score	0.121993 (rank : 187)
Query Neighborhood Hits	246	Target Neighborhood Hits	427	Shared Neighborhood Hits	57
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CSKP_MOUSE
θ value	3.0926 (rank : 195)	NC score	0.057344 (rank : 534)
Query Neighborhood Hits	246	Target Neighborhood Hits	1027	Shared Neighborhood Hits	91
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

GCC2_MOUSE
θ value	3.0926 (rank : 196)	NC score	0.062146 (rank : 450)
Query Neighborhood Hits	246	Target Neighborhood Hits	1619	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GLE1_MOUSE
θ value	3.0926 (rank : 197)	NC score	0.087318 (rank : 266)
Query Neighborhood Hits	246	Target Neighborhood Hits	504	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

K2C1_HUMAN
θ value	3.0926 (rank : 198)	NC score	0.023018 (rank : 758)
Query Neighborhood Hits	246	Target Neighborhood Hits	624	Shared Neighborhood Hits	42
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

RRBP1_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.056927 (rank : 552)
Query Neighborhood Hits	246	Target Neighborhood Hits	1306	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SPC24_HUMAN
θ value	3.0926 (rank : 200)	NC score	0.039988 (rank : 743)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

TDP2_MOUSE
θ value	3.0926 (rank : 201)	NC score	0.020978 (rank : 759)
Query Neighborhood Hits	246	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q64163	Gene names	Tfdp2, Dp2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2) (Dp-3).

M3K9_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.076443 (rank : 317)
Query Neighborhood Hits	246	Target Neighborhood Hits	1123	Shared Neighborhood Hits	112
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MYOM1_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.140300 (rank : 148)
Query Neighborhood Hits	246	Target Neighborhood Hits	405	Shared Neighborhood Hits	56
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NOS1_MOUSE
θ value	4.03905 (rank : 204)	NC score	0.011754 (rank : 773)
Query Neighborhood Hits	246	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NR1H4_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.005725 (rank : 779)
Query Neighborhood Hits	246	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

PLCB2_HUMAN
θ value	4.03905 (rank : 206)	NC score	0.036448 (rank : 750)
Query Neighborhood Hits	246	Target Neighborhood Hits	608	Shared Neighborhood Hits	36
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

ROS_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.043519 (rank : 738)
Query Neighborhood Hits	246	Target Neighborhood Hits	907	Shared Neighborhood Hits	64
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SNW1_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.026181 (rank : 753)
Query Neighborhood Hits	246	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

STAC_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.256264 (rank : 62)
Query Neighborhood Hits	246	Target Neighborhood Hits	276	Shared Neighborhood Hits	102
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TRAF3_HUMAN
θ value	4.03905 (rank : 210)	NC score	0.047004 (rank : 734)
Query Neighborhood Hits	246	Target Neighborhood Hits	463	Shared Neighborhood Hits	31
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	4.03905 (rank : 211)	NC score	0.046837 (rank : 735)
Query Neighborhood Hits	246	Target Neighborhood Hits	476	Shared Neighborhood Hits	32
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

CASL_HUMAN
θ value	5.27518 (rank : 212)	NC score	0.203240 (rank : 93)
Query Neighborhood Hits	246	Target Neighborhood Hits	259	Shared Neighborhood Hits	98
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

DMD_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.041899 (rank : 742)
Query Neighborhood Hits	246	Target Neighborhood Hits	1135	Shared Neighborhood Hits	55
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

GOGA1_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.062366 (rank : 444)
Query Neighborhood Hits	246	Target Neighborhood Hits	994	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

IASPP_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.145662 (rank : 142)
Query Neighborhood Hits	246	Target Neighborhood Hits	688	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.135021 (rank : 158)
Query Neighborhood Hits	246	Target Neighborhood Hits	1024	Shared Neighborhood Hits	104
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IMPG1_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.013826 (rank : 770)
Query Neighborhood Hits	246	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

K0999_MOUSE
θ value	5.27518 (rank : 218)	NC score	0.009504 (rank : 774)
Query Neighborhood Hits	246	Target Neighborhood Hits	931	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

MERTK_HUMAN
θ value	5.27518 (rank : 219)	NC score	0.052040 (rank : 676)
Query Neighborhood Hits	246	Target Neighborhood Hits	988	Shared Neighborhood Hits	59
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

PARG_MOUSE
θ value	5.27518 (rank : 220)	NC score	0.013359 (rank : 771)
Query Neighborhood Hits	246	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	O88622, Q80YQ6, Q8CB72	Gene names	Parg
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

SMC3_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.066442 (rank : 393)
Query Neighborhood Hits	246	Target Neighborhood Hits	1186	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	5.27518 (rank : 222)	NC score	0.066658 (rank : 391)
Query Neighborhood Hits	246	Target Neighborhood Hits	1187	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SNW1_MOUSE
θ value	5.27518 (rank : 223)	NC score	0.024947 (rank : 754)
Query Neighborhood Hits	246	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

STXB4_MOUSE
θ value	5.27518 (rank : 224)	NC score	0.038203 (rank : 746)
Query Neighborhood Hits	246	Target Neighborhood Hits	629	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TDP2_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.018443 (rank : 762)
Query Neighborhood Hits	246	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

IWS1_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.015123 (rank : 767)
Query Neighborhood Hits	246	Target Neighborhood Hits	1258	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

L1CAM_HUMAN
θ value	6.88961 (rank : 227)	NC score	0.126589 (rank : 172)
Query Neighborhood Hits	246	Target Neighborhood Hits	457	Shared Neighborhood Hits	55
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

MYOM1_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.134841 (rank : 159)
Query Neighborhood Hits	246	Target Neighborhood Hits	415	Shared Neighborhood Hits	53
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NIN_HUMAN
θ value	6.88961 (rank : 229)	NC score	0.062760 (rank : 439)
Query Neighborhood Hits	246	Target Neighborhood Hits	1416	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NRCAM_HUMAN
θ value	6.88961 (rank : 230)	NC score	0.132459 (rank : 164)
Query Neighborhood Hits	246	Target Neighborhood Hits	439	Shared Neighborhood Hits	52
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

RRBP1_MOUSE
θ value	6.88961 (rank : 231)	NC score	0.056439 (rank : 566)
Query Neighborhood Hits	246	Target Neighborhood Hits	1650	Shared Neighborhood Hits	64
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RUSC1_MOUSE
θ value	6.88961 (rank : 232)	NC score	0.130539 (rank : 167)
Query Neighborhood Hits	246	Target Neighborhood Hits	206	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SNPC4_MOUSE
θ value	6.88961 (rank : 233)	NC score	0.019851 (rank : 760)
Query Neighborhood Hits	246	Target Neighborhood Hits	237	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

ZFY16_MOUSE
θ value	6.88961 (rank : 234)	NC score	0.007977 (rank : 777)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

FNDC3_HUMAN
θ value	8.99809 (rank : 235)	NC score	0.183552 (rank : 105)
Query Neighborhood Hits	246	Target Neighborhood Hits	196	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

K0256_HUMAN
θ value	8.99809 (rank : 236)	NC score	0.018545 (rank : 761)
Query Neighborhood Hits	246	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q93073, Q8N767	Gene names	KIAA0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

K0256_MOUSE
θ value	8.99809 (rank : 237)	NC score	0.017706 (rank : 764)
Query Neighborhood Hits	246	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

K0999_HUMAN
θ value	8.99809 (rank : 238)	NC score	0.009390 (rank : 775)
Query Neighborhood Hits	246	Target Neighborhood Hits	899	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

MACF1_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.037400 (rank : 747)
Query Neighborhood Hits	246	Target Neighborhood Hits	1341	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.042397 (rank : 740)
Query Neighborhood Hits	246	Target Neighborhood Hits	1321	Shared Neighborhood Hits	63
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

PHLB2_MOUSE
θ value	8.99809 (rank : 241)	NC score	0.036507 (rank : 749)
Query Neighborhood Hits	246	Target Neighborhood Hits	1016	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PRP40_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.014302 (rank : 768)
Query Neighborhood Hits	246	Target Neighborhood Hits	447	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RBCC1_HUMAN
θ value	8.99809 (rank : 243)	NC score	0.050304 (rank : 726)
Query Neighborhood Hits	246	Target Neighborhood Hits	1023	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

TENS1_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.018309 (rank : 763)
Query Neighborhood Hits	246	Target Neighborhood Hits	400	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TPOR_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.009222 (rank : 776)
Query Neighborhood Hits	246	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

TR240_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.011952 (rank : 772)
Query Neighborhood Hits	246	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

ABI3_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.237755 (rank : 80)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	86
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.233960 (rank : 83)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABL1_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.050767 (rank : 713)
Query Neighborhood Hits	246	Target Neighborhood Hits	1220	Shared Neighborhood Hits	90
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.050443 (rank : 719)
Query Neighborhood Hits	246	Target Neighborhood Hits	1178	Shared Neighborhood Hits	92
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ADIP_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.053615 (rank : 634)
Query Neighborhood Hits	246	Target Neighborhood Hits	470	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

AKAP9_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.055983 (rank : 581)
Query Neighborhood Hits	246	Target Neighborhood Hits	1710	Shared Neighborhood Hits	63
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

AMOL2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.059838 (rank : 493)
Query Neighborhood Hits	246	Target Neighborhood Hits	603	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AMPH_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.089379 (rank : 253)
Query Neighborhood Hits	246	Target Neighborhood Hits	455	Shared Neighborhood Hits	66
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.079097 (rank : 300)
Query Neighborhood Hits	246	Target Neighborhood Hits	291	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANGL2_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.051762 (rank : 684)
Query Neighborhood Hits	246	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.050740 (rank : 715)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGP2_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.051499 (rank : 690)
Query Neighborhood Hits	246	Target Neighborhood Hits	400	Shared Neighborhood Hits	33
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANM2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.116973 (rank : 196)
Query Neighborhood Hits	246	Target Neighborhood Hits	175	Shared Neighborhood Hits	86
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.108375 (rank : 216)
Query Neighborhood Hits	246	Target Neighborhood Hits	175	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARHG1_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.058609 (rank : 517)
Query Neighborhood Hits	246	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.055367 (rank : 595)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.054302 (rank : 621)
Query Neighborhood Hits	246	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG3_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.080384 (rank : 294)
Query Neighborhood Hits	246	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.080305 (rank : 295)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.165881 (rank : 127)
Query Neighborhood Hits	246	Target Neighborhood Hits	242	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.140093 (rank : 149)
Query Neighborhood Hits	246	Target Neighborhood Hits	185	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG5_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.102400 (rank : 227)
Query Neighborhood Hits	246	Target Neighborhood Hits	172	Shared Neighborhood Hits	60
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG8_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.069708 (rank : 359)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.076125 (rank : 321)
Query Neighborhood Hits	246	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHG9_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.168594 (rank : 124)
Query Neighborhood Hits	246	Target Neighborhood Hits	235	Shared Neighborhood Hits	97
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.168838 (rank : 123)
Query Neighborhood Hits	246	Target Neighborhood Hits	234	Shared Neighborhood Hits	97
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHGA_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.067839 (rank : 378)
Query Neighborhood Hits	246	Target Neighborhood Hits	187	Shared Neighborhood Hits	24
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.069405 (rank : 362)
Query Neighborhood Hits	246	Target Neighborhood Hits	125	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.056892 (rank : 553)
Query Neighborhood Hits	246	Target Neighborhood Hits	375	Shared Neighborhood Hits	28
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.059602 (rank : 497)
Query Neighborhood Hits	246	Target Neighborhood Hits	351	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.059214 (rank : 505)
Query Neighborhood Hits	246	Target Neighborhood Hits	344	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.068051 (rank : 377)
Query Neighborhood Hits	246	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.079701 (rank : 297)
Query Neighborhood Hits	246	Target Neighborhood Hits	152	Shared Neighborhood Hits	36
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ASPP1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.129753 (rank : 169)
Query Neighborhood Hits	246	Target Neighborhood Hits	956	Shared Neighborhood Hits	129
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.135608 (rank : 157)
Query Neighborhood Hits	246	Target Neighborhood Hits	1244	Shared Neighborhood Hits	129
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

AZI1_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.073538 (rank : 326)
Query Neighborhood Hits	246	Target Neighborhood Hits	1000	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.070101 (rank : 353)
Query Neighborhood Hits	246	Target Neighborhood Hits	990	Shared Neighborhood Hits	62
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BAIP2_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.060295 (rank : 484)
Query Neighborhood Hits	246	Target Neighborhood Hits	192	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.062809 (rank : 437)
Query Neighborhood Hits	246	Target Neighborhood Hits	185	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BASI_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.060163 (rank : 486)
Query Neighborhood Hits	246	Target Neighborhood Hits	211	Shared Neighborhood Hits	32
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BASI_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.058787 (rank : 513)
Query Neighborhood Hits	246	Target Neighborhood Hits	238	Shared Neighborhood Hits	31
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BI2L1_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.086926 (rank : 267)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BI2L1_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.061963 (rank : 455)
Query Neighborhood Hits	246	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BICD2_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.057014 (rank : 546)
Query Neighborhood Hits	246	Target Neighborhood Hits	856	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.055086 (rank : 604)
Query Neighborhood Hits	246	Target Neighborhood Hits	864	Shared Neighborhood Hits	51
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BIN1_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.076257 (rank : 318)
Query Neighborhood Hits	246	Target Neighborhood Hits	335	Shared Neighborhood Hits	58
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.076725 (rank : 313)
Query Neighborhood Hits	246	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BLK_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.052588 (rank : 667)
Query Neighborhood Hits	246	Target Neighborhood Hits	994	Shared Neighborhood Hits	87
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.053802 (rank : 631)
Query Neighborhood Hits	246	Target Neighborhood Hits	992	Shared Neighborhood Hits	82
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BOC_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.108438 (rank : 215)
Query Neighborhood Hits	246	Target Neighborhood Hits	543	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

BOC_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.106190 (rank : 221)
Query Neighborhood Hits	246	Target Neighborhood Hits	433	Shared Neighborhood Hits	50
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

BPAEA_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.051662 (rank : 687)
Query Neighborhood Hits	246	Target Neighborhood Hits	1480	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRE1A_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.052792 (rank : 660)
Query Neighborhood Hits	246	Target Neighborhood Hits	1071	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1B_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.055750 (rank : 590)
Query Neighborhood Hits	246	Target Neighborhood Hits	1040	Shared Neighborhood Hits	43
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.051043 (rank : 703)
Query Neighborhood Hits	246	Target Neighborhood Hits	970	Shared Neighborhood Hits	42
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CAF1A_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.053527 (rank : 637)
Query Neighborhood Hits	246	Target Neighborhood Hits	750	Shared Neighborhood Hits	47
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.052759 (rank : 661)
Query Neighborhood Hits	246	Target Neighborhood Hits	736	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CALD1_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.056086 (rank : 579)
Query Neighborhood Hits	246	Target Neighborhood Hits	959	Shared Neighborhood Hits	51
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CAR10_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.065872 (rank : 399)
Query Neighborhood Hits	246	Target Neighborhood Hits	569	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CAR10_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.056838 (rank : 554)
Query Neighborhood Hits	246	Target Neighborhood Hits	407	Shared Neighborhood Hits	36
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

CAR11_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.055058 (rank : 606)
Query Neighborhood Hits	246	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CARD9_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.061033 (rank : 469)
Query Neighborhood Hits	246	Target Neighborhood Hits	602	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CASP_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.054656 (rank : 617)
Query Neighborhood Hits	246	Target Neighborhood Hits	1131	Shared Neighborhood Hits	55
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.053140 (rank : 650)
Query Neighborhood Hits	246	Target Neighborhood Hits	1152	Shared Neighborhood Hits	61
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCD11_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.057301 (rank : 535)
Query Neighborhood Hits	246	Target Neighborhood Hits	822	Shared Neighborhood Hits	48
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD11_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.054140 (rank : 626)
Query Neighborhood Hits	246	Target Neighborhood Hits	498	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD19_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.054285 (rank : 623)
Query Neighborhood Hits	246	Target Neighborhood Hits	639	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.069859 (rank : 357)
Query Neighborhood Hits	246	Target Neighborhood Hits	1135	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD41_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.055246 (rank : 599)
Query Neighborhood Hits	246	Target Neighborhood Hits	1139	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.060907 (rank : 474)
Query Neighborhood Hits	246	Target Neighborhood Hits	1399	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD42_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.060354 (rank : 481)
Query Neighborhood Hits	246	Target Neighborhood Hits	406	Shared Neighborhood Hits	34
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD42_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.056385 (rank : 568)
Query Neighborhood Hits	246	Target Neighborhood Hits	284	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD46_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.057792 (rank : 526)
Query Neighborhood Hits	246	Target Neighborhood Hits	1430	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.055558 (rank : 592)
Query Neighborhood Hits	246	Target Neighborhood Hits	1405	Shared Neighborhood Hits	66
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCDC6_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.051110 (rank : 699)
Query Neighborhood Hits	246	Target Neighborhood Hits	723	Shared Neighborhood Hits	42
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.056479 (rank : 563)
Query Neighborhood Hits	246	Target Neighborhood Hits	932	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CD22_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.055109 (rank : 602)
Query Neighborhood Hits	246	Target Neighborhood Hits	365	Shared Neighborhood Hits	31
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD22_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.060804 (rank : 476)
Query Neighborhood Hits	246	Target Neighborhood Hits	331	Shared Neighborhood Hits	29
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD45_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.063767 (rank : 421)
Query Neighborhood Hits	246	Target Neighborhood Hits	243	Shared Neighborhood Hits	39
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.055269 (rank : 597)
Query Neighborhood Hits	246	Target Neighborhood Hits	178	Shared Neighborhood Hits	26
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CDON_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.106815 (rank : 219)
Query Neighborhood Hits	246	Target Neighborhood Hits	412	Shared Neighborhood Hits	48
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CDON_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.108066 (rank : 217)
Query Neighborhood Hits	246	Target Neighborhood Hits	410	Shared Neighborhood Hits	49
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CDR2_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.052817 (rank : 657)
Query Neighborhood Hits	246	Target Neighborhood Hits	482	Shared Neighborhood Hits	37
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CE152_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.062752 (rank : 440)
Query Neighborhood Hits	246	Target Neighborhood Hits	976	Shared Neighborhood Hits	55
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CEAM1_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.050800 (rank : 711)
Query Neighborhood Hits	246	Target Neighborhood Hits	326	Shared Neighborhood Hits	33
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CEAM5_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.051916 (rank : 680)
Query Neighborhood Hits	246	Target Neighborhood Hits	343	Shared Neighborhood Hits	34
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

CENPE_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.050418 (rank : 722)
Query Neighborhood Hits	246	Target Neighborhood Hits	2060	Shared Neighborhood Hits	72
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CENPF_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.054197 (rank : 625)
Query Neighborhood Hits	246	Target Neighborhood Hits	1932	Shared Neighborhood Hits	77
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP55_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.053314 (rank : 644)
Query Neighborhood Hits	246	Target Neighborhood Hits	693	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP63_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.062964 (rank : 434)
Query Neighborhood Hits	246	Target Neighborhood Hits	1005	Shared Neighborhood Hits	55
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CF060_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.053467 (rank : 639)
Query Neighborhood Hits	246	Target Neighborhood Hits	1270	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CHL1_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.124636 (rank : 178)
Query Neighborhood Hits	246	Target Neighborhood Hits	413	Shared Neighborhood Hits	50
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

CHL1_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.114280 (rank : 207)
Query Neighborhood Hits	246	Target Neighborhood Hits	402	Shared Neighborhood Hits	49
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CI039_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.051206 (rank : 696)
Query Neighborhood Hits	246	Target Neighborhood Hits	1171	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.062134 (rank : 451)
Query Neighborhood Hits	246	Target Neighborhood Hits	1088	Shared Neighborhood Hits	52
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CI094_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.065561 (rank : 400)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CING_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.057534 (rank : 528)
Query Neighborhood Hits	246	Target Neighborhood Hits	1275	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CING_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.057239 (rank : 538)
Query Neighborhood Hits	246	Target Neighborhood Hits	1432	Shared Neighborhood Hits	65
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CIP4_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.096843 (rank : 240)
Query Neighborhood Hits	246	Target Neighborhood Hits	374	Shared Neighborhood Hits	57
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CK5P2_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.055522 (rank : 593)
Query Neighborhood Hits	246	Target Neighborhood Hits	1433	Shared Neighborhood Hits	71
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.050500 (rank : 718)
Query Neighborhood Hits	246	Target Neighborhood Hits	1151	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CKAP4_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.063051 (rank : 433)
Query Neighborhood Hits	246	Target Neighborhood Hits	592	Shared Neighborhood Hits	43
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CKAP4_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.052453 (rank : 669)
Query Neighborhood Hits	246	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CNTN1_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.118144 (rank : 193)
Query Neighborhood Hits	246	Target Neighborhood Hits	431	Shared Neighborhood Hits	50
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN1_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.116266 (rank : 200)
Query Neighborhood Hits	246	Target Neighborhood Hits	422	Shared Neighborhood Hits	49
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.117524 (rank : 195)
Query Neighborhood Hits	246	Target Neighborhood Hits	440	Shared Neighborhood Hits	51
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.116079 (rank : 201)
Query Neighborhood Hits	246	Target Neighborhood Hits	450	Shared Neighborhood Hits	50
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN5_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.115267 (rank : 205)
Query Neighborhood Hits	246	Target Neighborhood Hits	446	Shared Neighborhood Hits	50
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN5_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.116702 (rank : 198)
Query Neighborhood Hits	246	Target Neighborhood Hits	434	Shared Neighborhood Hits	50
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN6_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.120165 (rank : 190)
Query Neighborhood Hits	246	Target Neighborhood Hits	422	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CNTRB_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.062281 (rank : 446)
Query Neighborhood Hits	246	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CNTRB_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.063322 (rank : 430)
Query Neighborhood Hits	246	Target Neighborhood Hits	1029	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO7A1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.096990 (rank : 238)
Query Neighborhood Hits	246	Target Neighborhood Hits	807	Shared Neighborhood Hits	55
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COEA1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.125999 (rank : 174)
Query Neighborhood Hits	246	Target Neighborhood Hits	402	Shared Neighborhood Hits	55
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.115764 (rank : 204)
Query Neighborhood Hits	246	Target Neighborhood Hits	403	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CP135_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.051013 (rank : 704)
Query Neighborhood Hits	246	Target Neighborhood Hits	1290	Shared Neighborhood Hits	59
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.053416 (rank : 640)
Query Neighborhood Hits	246	Target Neighborhood Hits	1278	Shared Neighborhood Hits	57
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CRKL_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.253789 (rank : 66)
Query Neighborhood Hits	246	Target Neighborhood Hits	313	Shared Neighborhood Hits	111
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.251241 (rank : 69)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	112
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CROCC_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.066346 (rank : 394)
Query Neighborhood Hits	246	Target Neighborhood Hits	1409	Shared Neighborhood Hits	65
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.063993 (rank : 419)
Query Neighborhood Hits	246	Target Neighborhood Hits	1460	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CSF3R_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.072341 (rank : 338)
Query Neighborhood Hits	246	Target Neighborhood Hits	140	Shared Neighborhood Hits	45
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CSF3R_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.056127 (rank : 577)
Query Neighborhood Hits	246	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CT116_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.057460 (rank : 530)
Query Neighborhood Hits	246	Target Neighborhood Hits	294	Shared Neighborhood Hits	25
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

CT116_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.061491 (rank : 464)
Query Neighborhood Hits	246	Target Neighborhood Hits	268	Shared Neighborhood Hits	25
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

CT2NL_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.053595 (rank : 635)
Query Neighborhood Hits	246	Target Neighborhood Hits	1059	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CU013_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.056123 (rank : 578)
Query Neighborhood Hits	246	Target Neighborhood Hits	405	Shared Neighborhood Hits	36
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CYLN2_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.058140 (rank : 522)
Query Neighborhood Hits	246	Target Neighborhood Hits	1004	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.062024 (rank : 453)
Query Neighborhood Hits	246	Target Neighborhood Hits	1002	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DAPP1_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.050993 (rank : 706)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.051103 (rank : 700)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DBNL_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.199817 (rank : 94)
Query Neighborhood Hits	246	Target Neighborhood Hits	244	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.197303 (rank : 95)
Query Neighborhood Hits	246	Target Neighborhood Hits	306	Shared Neighborhood Hits	100
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DDEF1_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.125928 (rank : 175)
Query Neighborhood Hits	246	Target Neighborhood Hits	592	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.120987 (rank : 189)
Query Neighborhood Hits	246	Target Neighborhood Hits	599	Shared Neighborhood Hits	103
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.125214 (rank : 177)
Query Neighborhood Hits	246	Target Neighborhood Hits	625	Shared Neighborhood Hits	98
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DESP_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.057574 (rank : 527)
Query Neighborhood Hits	246	Target Neighborhood Hits	1470	Shared Neighborhood Hits	67
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DLG1_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.051439 (rank : 691)
Query Neighborhood Hits	246	Target Neighborhood Hits	290	Shared Neighborhood Hits	55
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.050759 (rank : 714)
Query Neighborhood Hits	246	Target Neighborhood Hits	285	Shared Neighborhood Hits	58
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG2_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.058924 (rank : 511)
Query Neighborhood Hits	246	Target Neighborhood Hits	279	Shared Neighborhood Hits	59
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.056340 (rank : 570)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	57
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.053665 (rank : 633)
Query Neighborhood Hits	246	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.053183 (rank : 649)
Query Neighborhood Hits	246	Target Neighborhood Hits	274	Shared Neighborhood Hits	55
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG5_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.058411 (rank : 518)
Query Neighborhood Hits	246	Target Neighborhood Hits	1088	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DOCK1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.069836 (rank : 358)
Query Neighborhood Hits	246	Target Neighborhood Hits	191	Shared Neighborhood Hits	74
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DSCAM_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.134750 (rank : 160)
Query Neighborhood Hits	246	Target Neighborhood Hits	524	Shared Neighborhood Hits	52
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DUET_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.064236 (rank : 414)
Query Neighborhood Hits	246	Target Neighborhood Hits	1220	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ECT2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.062174 (rank : 449)
Query Neighborhood Hits	246	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.065025 (rank : 405)
Query Neighborhood Hits	246	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EEA1_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.055094 (rank : 603)
Query Neighborhood Hits	246	Target Neighborhood Hits	1796	Shared Neighborhood Hits	69
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EEA1_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.054378 (rank : 619)
Query Neighborhood Hits	246	Target Neighborhood Hits	1637	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ENAH_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.059833 (rank : 494)
Query Neighborhood Hits	246	Target Neighborhood Hits	784	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.050429 (rank : 721)
Query Neighborhood Hits	246	Target Neighborhood Hits	919	Shared Neighborhood Hits	52
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP15R_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.063339 (rank : 429)
Query Neighborhood Hits	246	Target Neighborhood Hits	1083	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.065421 (rank : 404)
Query Neighborhood Hits	246	Target Neighborhood Hits	1135	Shared Neighborhood Hits	53
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.062554 (rank : 442)
Query Neighborhood Hits	246	Target Neighborhood Hits	1021	Shared Neighborhood Hits	53
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.063541 (rank : 423)
Query Neighborhood Hits	246	Target Neighborhood Hits	820	Shared Neighborhood Hits	54
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EPS8_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.082713 (rank : 280)
Query Neighborhood Hits	246	Target Neighborhood Hits	151	Shared Neighborhood Hits	66
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.081723 (rank : 284)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ERC2_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.060881 (rank : 475)
Query Neighborhood Hits	246	Target Neighborhood Hits	1156	Shared Neighborhood Hits	62
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.059795 (rank : 495)
Query Neighborhood Hits	246	Target Neighborhood Hits	1166	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ES8L1_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.074980 (rank : 322)
Query Neighborhood Hits	246	Target Neighborhood Hits	162	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L1_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.077504 (rank : 308)
Query Neighborhood Hits	246	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L2_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.100418 (rank : 232)
Query Neighborhood Hits	246	Target Neighborhood Hits	193	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.103222 (rank : 225)
Query Neighborhood Hits	246	Target Neighborhood Hits	169	Shared Neighborhood Hits	77
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L3_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.103347 (rank : 224)
Query Neighborhood Hits	246	Target Neighborhood Hits	206	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ES8L3_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.127394 (rank : 171)
Query Neighborhood Hits	246	Target Neighborhood Hits	168	Shared Neighborhood Hits	83
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

EVPL_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.061493 (rank : 463)
Query Neighborhood Hits	246	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.057833 (rank : 525)
Query Neighborhood Hits	246	Target Neighborhood Hits	952	Shared Neighborhood Hits	56
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

F107B_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.063195 (rank : 431)
Query Neighborhood Hits	246	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

F107B_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.061984 (rank : 454)
Query Neighborhood Hits	246	Target Neighborhood Hits	126	Shared Neighborhood Hits	16
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

FCRL2_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.059265 (rank : 503)
Query Neighborhood Hits	246	Target Neighborhood Hits	251	Shared Neighborhood Hits	29
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.055042 (rank : 608)
Query Neighborhood Hits	246	Target Neighborhood Hits	267	Shared Neighborhood Hits	29
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FGRL1_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.088870 (rank : 257)
Query Neighborhood Hits	246	Target Neighborhood Hits	335	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.086694 (rank : 268)
Query Neighborhood Hits	246	Target Neighborhood Hits	325	Shared Neighborhood Hits	33
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FLIP1_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.059493 (rank : 499)
Query Neighborhood Hits	246	Target Neighborhood Hits	1405	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.054812 (rank : 613)
Query Neighborhood Hits	246	Target Neighborhood Hits	1176	Shared Neighborhood Hits	64
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FNBP2_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.111358 (rank : 213)
Query Neighborhood Hits	246	Target Neighborhood Hits	432	Shared Neighborhood Hits	104
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FNDC3_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.178130 (rank : 107)
Query Neighborhood Hits	246	Target Neighborhood Hits	207	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FRK_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.055966 (rank : 582)
Query Neighborhood Hits	246	Target Neighborhood Hits	1058	Shared Neighborhood Hits	112
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FSTL4_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.067161 (rank : 384)
Query Neighborhood Hits	246	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.069083 (rank : 367)
Query Neighborhood Hits	246	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.068672 (rank : 373)
Query Neighborhood Hits	246	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.069172 (rank : 365)
Query Neighborhood Hits	246	Target Neighborhood Hits	355	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FYCO1_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.053535 (rank : 636)
Query Neighborhood Hits	246	Target Neighborhood Hits	1149	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.051776 (rank : 683)
Query Neighborhood Hits	246	Target Neighborhood Hits	1059	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

FYN_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.077957 (rank : 303)
Query Neighborhood Hits	246	Target Neighborhood Hits	1078	Shared Neighborhood Hits	117
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.079192 (rank : 299)
Query Neighborhood Hits	246	Target Neighborhood Hits	1073	Shared Neighborhood Hits	116
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GAS8_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.061784 (rank : 459)
Query Neighborhood Hits	246	Target Neighborhood Hits	819	Shared Neighborhood Hits	47
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.055046 (rank : 607)
Query Neighborhood Hits	246	Target Neighborhood Hits	622	Shared Neighborhood Hits	44
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCC1_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.060114 (rank : 487)
Query Neighborhood Hits	246	Target Neighborhood Hits	887	Shared Neighborhood Hits	47
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.059956 (rank : 492)
Query Neighborhood Hits	246	Target Neighborhood Hits	777	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCP60_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.053948 (rank : 627)
Query Neighborhood Hits	246	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GCP60_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.056604 (rank : 558)
Query Neighborhood Hits	246	Target Neighborhood Hits	395	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GNRP_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.050806 (rank : 710)
Query Neighborhood Hits	246	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GOG8A_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.067335 (rank : 383)
Query Neighborhood Hits	246	Target Neighborhood Hits	635	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA2_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.066517 (rank : 392)
Query Neighborhood Hits	246	Target Neighborhood Hits	856	Shared Neighborhood Hits	52
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA2_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.064723 (rank : 409)
Query Neighborhood Hits	246	Target Neighborhood Hits	944	Shared Neighborhood Hits	55
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.059576 (rank : 498)
Query Neighborhood Hits	246	Target Neighborhood Hits	1317	Shared Neighborhood Hits	65
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.057496 (rank : 529)
Query Neighborhood Hits	246	Target Neighborhood Hits	1437	Shared Neighborhood Hits	65
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA4_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.054721 (rank : 616)
Query Neighborhood Hits	246	Target Neighborhood Hits	2034	Shared Neighborhood Hits	83
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA4_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.056206 (rank : 575)
Query Neighborhood Hits	246	Target Neighborhood Hits	1939	Shared Neighborhood Hits	72
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.052718 (rank : 664)
Query Neighborhood Hits	246	Target Neighborhood Hits	1168	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.056306 (rank : 572)
Query Neighborhood Hits	246	Target Neighborhood Hits	1434	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.061001 (rank : 470)
Query Neighborhood Hits	246	Target Neighborhood Hits	1007	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GOGB1_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.058165 (rank : 521)
Query Neighborhood Hits	246	Target Neighborhood Hits	2297	Shared Neighborhood Hits	80
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRAP1_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.058063 (rank : 523)
Query Neighborhood Hits	246	Target Neighborhood Hits	944	Shared Neighborhood Hits	58
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GRAP1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.056402 (rank : 567)
Query Neighborhood Hits	246	Target Neighborhood Hits	1234	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HAP1_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.053310 (rank : 645)
Query Neighborhood Hits	246	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HAPIP_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.054893 (rank : 611)
Query Neighborhood Hits	246	Target Neighborhood Hits	350	Shared Neighborhood Hits	40
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HCFC2_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.056809 (rank : 556)
Query Neighborhood Hits	246	Target Neighborhood Hits	97	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HCK_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.059970 (rank : 491)
Query Neighborhood Hits	246	Target Neighborhood Hits	1035	Shared Neighborhood Hits	105
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.060514 (rank : 480)
Query Neighborhood Hits	246	Target Neighborhood Hits	1029	Shared Neighborhood Hits	105
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HCLS1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.257707 (rank : 61)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	104
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.256213 (rank : 63)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	106
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HIP1R_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.053003 (rank : 654)
Query Neighborhood Hits	246	Target Neighborhood Hits	809	Shared Neighborhood Hits	50
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.051785 (rank : 682)
Query Neighborhood Hits	246	Target Neighborhood Hits	959	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HMCN1_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.059657 (rank : 496)
Query Neighborhood Hits	246	Target Neighborhood Hits	983	Shared Neighborhood Hits	39
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HMMR_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.056440 (rank : 565)
Query Neighborhood Hits	246	Target Neighborhood Hits	1082	Shared Neighborhood Hits	58
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.054302 (rank : 622)
Query Neighborhood Hits	246	Target Neighborhood Hits	1178	Shared Neighborhood Hits	62
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOME1_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.052043 (rank : 675)
Query Neighborhood Hits	246	Target Neighborhood Hits	630	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

HOOK1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.059236 (rank : 504)
Query Neighborhood Hits	246	Target Neighborhood Hits	942	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.066319 (rank : 395)
Query Neighborhood Hits	246	Target Neighborhood Hits	910	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.065960 (rank : 398)
Query Neighborhood Hits	246	Target Neighborhood Hits	714	Shared Neighborhood Hits	46
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HOOK2_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.063432 (rank : 426)
Query Neighborhood Hits	246	Target Neighborhood Hits	736	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

HOOK3_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.061573 (rank : 462)
Query Neighborhood Hits	246	Target Neighborhood Hits	1070	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.061933 (rank : 456)
Query Neighborhood Hits	246	Target Neighborhood Hits	1007	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

I12R1_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.060348 (rank : 482)
Query Neighborhood Hits	246	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I12R1_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.053189 (rank : 648)
Query Neighborhood Hits	246	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

I12R2_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.089420 (rank : 252)
Query Neighborhood Hits	246	Target Neighborhood Hits	163	Shared Neighborhood Hits	44
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.085636 (rank : 271)
Query Neighborhood Hits	246	Target Neighborhood Hits	143	Shared Neighborhood Hits	44
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IBP7_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.066946 (rank : 388)
Query Neighborhood Hits	246	Target Neighborhood Hits	220	Shared Neighborhood Hits	29
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.073338 (rank : 330)
Query Neighborhood Hits	246	Target Neighborhood Hits	230	Shared Neighborhood Hits	32
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ICAM5_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.064023 (rank : 418)
Query Neighborhood Hits	246	Target Neighborhood Hits	276	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

ICAM5_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.067070 (rank : 386)
Query Neighborhood Hits	246	Target Neighborhood Hits	308	Shared Neighborhood Hits	31
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IF31_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.051192 (rank : 698)
Query Neighborhood Hits	246	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

IF31_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.050936 (rank : 709)
Query Neighborhood Hits	246	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q66JS6, Q8BUW6	Gene names	Eif3s1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha).

IF3A_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.060198 (rank : 485)
Query Neighborhood Hits	246	Target Neighborhood Hits	875	Shared Neighborhood Hits	51
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.062557 (rank : 441)
Query Neighborhood Hits	246	Target Neighborhood Hits	871	Shared Neighborhood Hits	50
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.052794 (rank : 659)
Query Neighborhood Hits	246	Target Neighborhood Hits	939	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.052916 (rank : 655)
Query Neighborhood Hits	246	Target Neighborhood Hits	893	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.055879 (rank : 588)
Query Neighborhood Hits	246	Target Neighborhood Hits	959	Shared Neighborhood Hits	45
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IGS4B_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.052335 (rank : 672)
Query Neighborhood Hits	246	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

IGS4B_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.052916 (rank : 656)
Query Neighborhood Hits	246	Target Neighborhood Hits	328	Shared Neighborhood Hits	30
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IL27B_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.050779 (rank : 712)
Query Neighborhood Hits	246	Target Neighborhood Hits	80	Shared Neighborhood Hits	31
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IL6RB_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.089137 (rank : 254)
Query Neighborhood Hits	246	Target Neighborhood Hits	181	Shared Neighborhood Hits	43
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.088292 (rank : 259)
Query Neighborhood Hits	246	Target Neighborhood Hits	168	Shared Neighborhood Hits	44
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

INCE_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.073485 (rank : 327)
Query Neighborhood Hits	246	Target Neighborhood Hits	978	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.069070 (rank : 368)
Query Neighborhood Hits	246	Target Neighborhood Hits	903	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INVO_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.074419 (rank : 325)
Query Neighborhood Hits	246	Target Neighborhood Hits	636	Shared Neighborhood Hits	44
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.061577 (rank : 461)
Query Neighborhood Hits	246	Target Neighborhood Hits	474	Shared Neighborhood Hits	37
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

ITB4_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.096204 (rank : 243)
Query Neighborhood Hits	246	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

JAM1_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.064567 (rank : 410)
Query Neighborhood Hits	246	Target Neighborhood Hits	294	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM1_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.064431 (rank : 412)
Query Neighborhood Hits	246	Target Neighborhood Hits	287	Shared Neighborhood Hits	32
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAM2_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.060948 (rank : 472)
Query Neighborhood Hits	246	Target Neighborhood Hits	304	Shared Neighborhood Hits	33
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM2_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.056261 (rank : 574)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM3_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.072582 (rank : 335)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAM3_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.067581 (rank : 381)
Query Neighborhood Hits	246	Target Neighborhood Hits	286	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JIP1_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.051889 (rank : 681)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP2_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.052323 (rank : 673)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	44
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K0552_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.070924 (rank : 344)
Query Neighborhood Hits	246	Target Neighborhood Hits	442	Shared Neighborhood Hits	36
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

KALM_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.082557 (rank : 281)
Query Neighborhood Hits	246	Target Neighborhood Hits	114	Shared Neighborhood Hits	33
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KAZD1_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.076978 (rank : 310)
Query Neighborhood Hits	246	Target Neighborhood Hits	248	Shared Neighborhood Hits	32
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.077933 (rank : 304)
Query Neighborhood Hits	246	Target Neighborhood Hits	281	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KGUA_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.056987 (rank : 548)
Query Neighborhood Hits	246	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.057241 (rank : 537)
Query Neighborhood Hits	246	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KIRR1_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.063486 (rank : 424)
Query Neighborhood Hits	246	Target Neighborhood Hits	401	Shared Neighborhood Hits	31
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR1_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.062194 (rank : 448)
Query Neighborhood Hits	246	Target Neighborhood Hits	403	Shared Neighborhood Hits	31
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR2_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.072916 (rank : 332)
Query Neighborhood Hits	246	Target Neighborhood Hits	321	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

KIRR2_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.071612 (rank : 340)
Query Neighborhood Hits	246	Target Neighborhood Hits	326	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KIRR3_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.063344 (rank : 428)
Query Neighborhood Hits	246	Target Neighborhood Hits	302	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

KIRR3_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.062495 (rank : 443)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KTN1_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.056302 (rank : 573)
Query Neighborhood Hits	246	Target Neighborhood Hits	1197	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.059109 (rank : 507)
Query Neighborhood Hits	246	Target Neighborhood Hits	1324	Shared Neighborhood Hits	59
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

L1CAM_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.122501 (rank : 186)
Query Neighborhood Hits	246	Target Neighborhood Hits	457	Shared Neighborhood Hits	55
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LASP1_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.196416 (rank : 96)
Query Neighborhood Hits	246	Target Neighborhood Hits	293	Shared Neighborhood Hits	91
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.194595 (rank : 99)
Query Neighborhood Hits	246	Target Neighborhood Hits	297	Shared Neighborhood Hits	91
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LBC_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.052282 (rank : 674)
Query Neighborhood Hits	246	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LIFR_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.084942 (rank : 274)
Query Neighborhood Hits	246	Target Neighborhood Hits	130	Shared Neighborhood Hits	39
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.084930 (rank : 275)
Query Neighborhood Hits	246	Target Neighborhood Hits	127	Shared Neighborhood Hits	38
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

LIPA2_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.052576 (rank : 668)
Query Neighborhood Hits	246	Target Neighborhood Hits	1282	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LMO7_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.053254 (rank : 646)
Query Neighborhood Hits	246	Target Neighborhood Hits	507	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LNK_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.054976 (rank : 610)
Query Neighborhood Hits	246	Target Neighborhood Hits	151	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LRC45_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.065009 (rank : 406)
Query Neighborhood Hits	246	Target Neighborhood Hits	933	Shared Neighborhood Hits	47
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.071048 (rank : 343)
Query Neighborhood Hits	246	Target Neighborhood Hits	959	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRIG1_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.057045 (rank : 545)
Query Neighborhood Hits	246	Target Neighborhood Hits	654	Shared Neighborhood Hits	35
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.057100 (rank : 543)
Query Neighborhood Hits	246	Target Neighborhood Hits	627	Shared Neighborhood Hits	36
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.057180 (rank : 541)
Query Neighborhood Hits	246	Target Neighborhood Hits	595	Shared Neighborhood Hits	35
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.057070 (rank : 544)
Query Neighborhood Hits	246	Target Neighborhood Hits	586	Shared Neighborhood Hits	35
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.056333 (rank : 571)
Query Neighborhood Hits	246	Target Neighborhood Hits	601	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.056496 (rank : 562)
Query Neighborhood Hits	246	Target Neighborhood Hits	611	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LRRF2_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.060616 (rank : 478)
Query Neighborhood Hits	246	Target Neighborhood Hits	791	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LSAMP_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.069101 (rank : 366)
Query Neighborhood Hits	246	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.069942 (rank : 356)
Query Neighborhood Hits	246	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LUZP1_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.052033 (rank : 677)
Query Neighborhood Hits	246	Target Neighborhood Hits	739	Shared Neighborhood Hits	46
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LU_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.062031 (rank : 452)
Query Neighborhood Hits	246	Target Neighborhood Hits	283	Shared Neighborhood Hits	33
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LYN_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.056936 (rank : 550)
Query Neighborhood Hits	246	Target Neighborhood Hits	1022	Shared Neighborhood Hits	99
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.058640 (rank : 515)
Query Neighborhood Hits	246	Target Neighborhood Hits	1023	Shared Neighborhood Hits	100
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LZTS1_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.058913 (rank : 512)
Query Neighborhood Hits	246	Target Neighborhood Hits	532	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS1_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.055266 (rank : 598)
Query Neighborhood Hits	246	Target Neighborhood Hits	540	Shared Neighborhood Hits	39
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS2_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.067124 (rank : 385)
Query Neighborhood Hits	246	Target Neighborhood Hits	427	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

M3K10_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.070823 (rank : 345)
Query Neighborhood Hits	246	Target Neighborhood Hits	1071	Shared Neighborhood Hits	111
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MACOI_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.064558 (rank : 411)
Query Neighborhood Hits	246	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.065518 (rank : 401)
Query Neighborhood Hits	246	Target Neighborhood Hits	620	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MAG_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.068802 (rank : 372)
Query Neighborhood Hits	246	Target Neighborhood Hits	278	Shared Neighborhood Hits	32
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.069527 (rank : 360)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MALT1_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.082383 (rank : 282)
Query Neighborhood Hits	246	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MAMC1_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.076499 (rank : 316)
Query Neighborhood Hits	246	Target Neighborhood Hits	357	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.076763 (rank : 312)
Query Neighborhood Hits	246	Target Neighborhood Hits	357	Shared Neighborhood Hits	33
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MARCS_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.059462 (rank : 502)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MCF2L_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.077726 (rank : 306)
Query Neighborhood Hits	246	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.062319 (rank : 445)
Query Neighborhood Hits	246	Target Neighborhood Hits	166	Shared Neighborhood Hits	24
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MD1L1_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.060929 (rank : 473)
Query Neighborhood Hits	246	Target Neighborhood Hits	893	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.056700 (rank : 557)
Query Neighborhood Hits	246	Target Neighborhood Hits	1001	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MDGA1_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.074548 (rank : 324)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MFA3L_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.056578 (rank : 559)
Query Neighborhood Hits	246	Target Neighborhood Hits	230	Shared Neighborhood Hits	32
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MFA3L_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.051402 (rank : 693)
Query Neighborhood Hits	246	Target Neighborhood Hits	214	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MFAP1_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.050221 (rank : 727)
Query Neighborhood Hits	246	Target Neighborhood Hits	353	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

MPP4_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.081045 (rank : 290)
Query Neighborhood Hits	246	Target Neighborhood Hits	205	Shared Neighborhood Hits	44
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP5_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.097428 (rank : 235)
Query Neighborhood Hits	246	Target Neighborhood Hits	231	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.096878 (rank : 239)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MUC18_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.068953 (rank : 371)
Query Neighborhood Hits	246	Target Neighborhood Hits	275	Shared Neighborhood Hits	34
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

MUC18_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.064266 (rank : 413)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

MUSK_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.056936 (rank : 549)
Query Neighborhood Hits	246	Target Neighborhood Hits	1074	Shared Neighborhood Hits	53
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.057229 (rank : 540)
Query Neighborhood Hits	246	Target Neighborhood Hits	1057	Shared Neighborhood Hits	53
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MY18A_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.055939 (rank : 584)
Query Neighborhood Hits	246	Target Neighborhood Hits	1929	Shared Neighborhood Hits	87
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.056500 (rank : 561)
Query Neighborhood Hits	246	Target Neighborhood Hits	1989	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18B_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.050531 (rank : 717)
Query Neighborhood Hits	246	Target Neighborhood Hits	1299	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYBPH_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.076608 (rank : 315)
Query Neighborhood Hits	246	Target Neighborhood Hits	256	Shared Neighborhood Hits	42
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYBPH_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.078671 (rank : 302)
Query Neighborhood Hits	246	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYH10_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.053111 (rank : 651)
Query Neighborhood Hits	246	Target Neighborhood Hits	1620	Shared Neighborhood Hits	67
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.053078 (rank : 652)
Query Neighborhood Hits	246	Target Neighborhood Hits	1612	Shared Neighborhood Hits	67
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH14_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.052756 (rank : 662)
Query Neighborhood Hits	246	Target Neighborhood Hits	995	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.052683 (rank : 666)
Query Neighborhood Hits	246	Target Neighborhood Hits	1225	Shared Neighborhood Hits	57
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH1_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.050084 (rank : 729)
Query Neighborhood Hits	246	Target Neighborhood Hits	1461	Shared Neighborhood Hits	71
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH3_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.050057 (rank : 730)
Query Neighborhood Hits	246	Target Neighborhood Hits	1660	Shared Neighborhood Hits	76
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH9_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.057249 (rank : 536)
Query Neighborhood Hits	246	Target Neighborhood Hits	1762	Shared Neighborhood Hits	75
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO1E_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.123920 (rank : 182)
Query Neighborhood Hits	246	Target Neighborhood Hits	293	Shared Neighborhood Hits	110
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYOM2_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.132518 (rank : 163)
Query Neighborhood Hits	246	Target Neighborhood Hits	341	Shared Neighborhood Hits	51
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

MYOTI_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.086513 (rank : 269)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.087612 (rank : 263)
Query Neighborhood Hits	246	Target Neighborhood Hits	297	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYPC1_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.103710 (rank : 223)
Query Neighborhood Hits	246	Target Neighborhood Hits	303	Shared Neighborhood Hits	50
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

MYPC2_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.110308 (rank : 214)
Query Neighborhood Hits	246	Target Neighborhood Hits	316	Shared Neighborhood Hits	51
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPC2_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.112380 (rank : 210)
Query Neighborhood Hits	246	Target Neighborhood Hits	297	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPN_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.088996 (rank : 255)
Query Neighborhood Hits	246	Target Neighborhood Hits	418	Shared Neighborhood Hits	37
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPN_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.087872 (rank : 262)
Query Neighborhood Hits	246	Target Neighborhood Hits	421	Shared Neighborhood Hits	38
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

N4BP3_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.050010 (rank : 732)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

NAF1_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.055915 (rank : 585)
Query Neighborhood Hits	246	Target Neighborhood Hits	937	Shared Neighborhood Hits	43
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.057384 (rank : 533)
Query Neighborhood Hits	246	Target Neighborhood Hits	852	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCA11_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.091667 (rank : 248)
Query Neighborhood Hits	246	Target Neighborhood Hits	443	Shared Neighborhood Hits	45
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA11_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.092364 (rank : 246)
Query Neighborhood Hits	246	Target Neighborhood Hits	661	Shared Neighborhood Hits	51
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.088198 (rank : 260)
Query Neighborhood Hits	246	Target Neighborhood Hits	437	Shared Neighborhood Hits	45
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCA12_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.090601 (rank : 250)
Query Neighborhood Hits	246	Target Neighborhood Hits	399	Shared Neighborhood Hits	44
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

NCAM2_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.097332 (rank : 237)
Query Neighborhood Hits	246	Target Neighborhood Hits	441	Shared Neighborhood Hits	48
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

NCAM2_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.100424 (rank : 231)
Query Neighborhood Hits	246	Target Neighborhood Hits	472	Shared Neighborhood Hits	49
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NCF4_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.235146 (rank : 82)
Query Neighborhood Hits	246	Target Neighborhood Hits	161	Shared Neighborhood Hits	83
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.252204 (rank : 68)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	93
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NDE1_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.058300 (rank : 519)
Query Neighborhood Hits	246	Target Neighborhood Hits	823	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NEB1_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.055654 (rank : 591)
Query Neighborhood Hits	246	Target Neighborhood Hits	829	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEBL_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.196073 (rank : 97)
Query Neighborhood Hits	246	Target Neighborhood Hits	457	Shared Neighborhood Hits	117
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.150337 (rank : 140)
Query Neighborhood Hits	246	Target Neighborhood Hits	420	Shared Neighborhood Hits	100
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NEGR1_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.070638 (rank : 346)
Query Neighborhood Hits	246	Target Neighborhood Hits	346	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.069192 (rank : 363)
Query Neighborhood Hits	246	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

NEMO_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.061053 (rank : 468)
Query Neighborhood Hits	246	Target Neighborhood Hits	820	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEMO_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.056929 (rank : 551)
Query Neighborhood Hits	246	Target Neighborhood Hits	658	Shared Neighborhood Hits	45
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NFASC_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.121725 (rank : 188)
Query Neighborhood Hits	246	Target Neighborhood Hits	497	Shared Neighborhood Hits	52
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NFASC_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.118003 (rank : 194)
Query Neighborhood Hits	246	Target Neighborhood Hits	475	Shared Neighborhood Hits	55
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

NGEF_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.096816 (rank : 241)
Query Neighborhood Hits	246	Target Neighborhood Hits	166	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.100029 (rank : 233)
Query Neighborhood Hits	246	Target Neighborhood Hits	228	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NIN_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.060082 (rank : 488)
Query Neighborhood Hits	246	Target Neighborhood Hits	1376	Shared Neighborhood Hits	62
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NOXO1_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.102818 (rank : 226)
Query Neighborhood Hits	246	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.155063 (rank : 134)
Query Neighborhood Hits	246	Target Neighborhood Hits	114	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHN_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.101584 (rank : 229)
Query Neighborhood Hits	246	Target Neighborhood Hits	362	Shared Neighborhood Hits	49
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NPHN_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.096390 (rank : 242)
Query Neighborhood Hits	246	Target Neighborhood Hits	370	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NPHP1_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.190927 (rank : 102)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.183806 (rank : 104)
Query Neighborhood Hits	246	Target Neighborhood Hits	267	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NPTN_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.069047 (rank : 369)
Query Neighborhood Hits	246	Target Neighborhood Hits	212	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NPTN_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.069447 (rank : 361)
Query Neighborhood Hits	246	Target Neighborhood Hits	216	Shared Neighborhood Hits	32
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRCAM_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.122793 (rank : 185)
Query Neighborhood Hits	246	Target Neighborhood Hits	432	Shared Neighborhood Hits	49
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

NRG2_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.066675 (rank : 390)
Query Neighborhood Hits	246	Target Neighborhood Hits	419	Shared Neighborhood Hits	40
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.050413 (rank : 723)
Query Neighborhood Hits	246	Target Neighborhood Hits	392	Shared Neighborhood Hits	33
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NTRI_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.062767 (rank : 438)
Query Neighborhood Hits	246	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NTRI_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.063969 (rank : 420)
Query Neighborhood Hits	246	Target Neighborhood Hits	342	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NUMA1_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.062943 (rank : 435)
Query Neighborhood Hits	246	Target Neighborhood Hits	1523	Shared Neighborhood Hits	75
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

OBSCN_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.059470 (rank : 500)
Query Neighborhood Hits	246	Target Neighborhood Hits	1931	Shared Neighborhood Hits	89
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OBSL1_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.097454 (rank : 234)
Query Neighborhood Hits	246	Target Neighborhood Hits	354	Shared Neighborhood Hits	34
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

OPCM_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.068282 (rank : 374)
Query Neighborhood Hits	246	Target Neighborhood Hits	332	Shared Neighborhood Hits	33
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

OPTN_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.054316 (rank : 620)
Query Neighborhood Hits	246	Target Neighborhood Hits	827	Shared Neighborhood Hits	45
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.058696 (rank : 514)
Query Neighborhood Hits	246	Target Neighborhood Hits	1120	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

P55G_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.059196 (rank : 506)
Query Neighborhood Hits	246	Target Neighborhood Hits	451	Shared Neighborhood Hits	56
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.056819 (rank : 555)
Query Neighborhood Hits	246	Target Neighborhood Hits	401	Shared Neighborhood Hits	52
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85A_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.081543 (rank : 286)
Query Neighborhood Hits	246	Target Neighborhood Hits	479	Shared Neighborhood Hits	82
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.083392 (rank : 279)
Query Neighborhood Hits	246	Target Neighborhood Hits	435	Shared Neighborhood Hits	77
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.071216 (rank : 342)
Query Neighborhood Hits	246	Target Neighborhood Hits	543	Shared Neighborhood Hits	64
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.069180 (rank : 364)
Query Neighborhood Hits	246	Target Neighborhood Hits	519	Shared Neighborhood Hits	68
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCNT_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.064178 (rank : 415)
Query Neighborhood Hits	246	Target Neighborhood Hits	1207	Shared Neighborhood Hits	60
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PEPL_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.057002 (rank : 547)
Query Neighborhood Hits	246	Target Neighborhood Hits	1141	Shared Neighborhood Hits	51
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.061262 (rank : 467)
Query Neighborhood Hits	246	Target Neighborhood Hits	1105	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PEX13_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.162829 (rank : 130)
Query Neighborhood Hits	246	Target Neighborhood Hits	128	Shared Neighborhood Hits	75
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.166955 (rank : 126)
Query Neighborhood Hits	246	Target Neighborhood Hits	126	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PGBM_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.063073 (rank : 432)
Query Neighborhood Hits	246	Target Neighborhood Hits	1113	Shared Neighborhood Hits	45
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.061899 (rank : 457)
Query Neighborhood Hits	246	Target Neighborhood Hits	1073	Shared Neighborhood Hits	45
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PHLB1_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.053354 (rank : 643)
Query Neighborhood Hits	246	Target Neighborhood Hits	1038	Shared Neighborhood Hits	48
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.051665 (rank : 686)
Query Neighborhood Hits	246	Target Neighborhood Hits	678	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB3_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.056068 (rank : 580)
Query Neighborhood Hits	246	Target Neighborhood Hits	304	Shared Neighborhood Hits	30
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

PIBF1_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.051229 (rank : 695)
Query Neighborhood Hits	246	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PKHG1_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.084593 (rank : 277)
Query Neighborhood Hits	246	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PLCG1_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.167941 (rank : 125)
Query Neighborhood Hits	246	Target Neighborhood Hits	293	Shared Neighborhood Hits	96
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.173000 (rank : 115)
Query Neighborhood Hits	246	Target Neighborhood Hits	314	Shared Neighborhood Hits	99
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLEC1_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.051422 (rank : 692)
Query Neighborhood Hits	246	Target Neighborhood Hits	1326	Shared Neighborhood Hits	63
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PLVAP_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.054438 (rank : 618)
Query Neighborhood Hits	246	Target Neighborhood Hits	397	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

PPIP2_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.088935 (rank : 256)
Query Neighborhood Hits	246	Target Neighborhood Hits	254	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

PPIP2_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.084625 (rank : 276)
Query Neighborhood Hits	246	Target Neighborhood Hits	308	Shared Neighborhood Hits	38
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PREX1_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.077135 (rank : 309)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PTK6_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.050184 (rank : 728)
Query Neighborhood Hits	246	Target Neighborhood Hits	1026	Shared Neighborhood Hits	97
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTK7_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.060747 (rank : 477)
Query Neighborhood Hits	246	Target Neighborhood Hits	1103	Shared Neighborhood Hits	54
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

PTN11_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.070295 (rank : 351)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.070296 (rank : 350)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN6_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.067687 (rank : 380)
Query Neighborhood Hits	246	Target Neighborhood Hits	234	Shared Neighborhood Hits	33
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.067810 (rank : 379)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	33
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRA_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.053853 (rank : 628)
Query Neighborhood Hits	246	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.053838 (rank : 630)
Query Neighborhood Hits	246	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.053725 (rank : 632)
Query Neighborhood Hits	246	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.053849 (rank : 629)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRG_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.050323 (rank : 725)
Query Neighborhood Hits	246	Target Neighborhood Hits	231	Shared Neighborhood Hits	24
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.051085 (rank : 701)
Query Neighborhood Hits	246	Target Neighborhood Hits	260	Shared Neighborhood Hits	24
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.081920 (rank : 283)
Query Neighborhood Hits	246	Target Neighborhood Hits	207	Shared Neighborhood Hits	36
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.081428 (rank : 287)
Query Neighborhood Hits	246	Target Neighborhood Hits	188	Shared Neighborhood Hits	34
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.072576 (rank : 336)
Query Neighborhood Hits	246	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.073483 (rank : 328)
Query Neighborhood Hits	246	Target Neighborhood Hits	223	Shared Neighborhood Hits	46
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.087597 (rank : 264)
Query Neighborhood Hits	246	Target Neighborhood Hits	244	Shared Neighborhood Hits	46
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.088056 (rank : 261)
Query Neighborhood Hits	246	Target Neighborhood Hits	238	Shared Neighborhood Hits	47
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRO_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.071811 (rank : 339)
Query Neighborhood Hits	246	Target Neighborhood Hits	139	Shared Neighborhood Hits	30
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRT_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.085067 (rank : 273)
Query Neighborhood Hits	246	Target Neighborhood Hits	217	Shared Neighborhood Hits	46
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.085426 (rank : 272)
Query Neighborhood Hits	246	Target Neighborhood Hits	219	Shared Neighborhood Hits	47
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.080472 (rank : 293)
Query Neighborhood Hits	246	Target Neighborhood Hits	237	Shared Neighborhood Hits	46
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.088784 (rank : 258)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	38
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.051393 (rank : 694)
Query Neighborhood Hits	246	Target Neighborhood Hits	255	Shared Neighborhood Hits	23
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PUNC_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.124139 (rank : 181)
Query Neighborhood Hits	246	Target Neighborhood Hits	449	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PUNC_MOUSE
θ value	θ > 10 (rank : 686)	NC score	0.124244 (rank : 179)
Query Neighborhood Hits	246	Target Neighborhood Hits	501	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RABE1_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.051703 (rank : 685)
Query Neighborhood Hits	246	Target Neighborhood Hits	1104	Shared Neighborhood Hits	55
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE2_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.051604 (rank : 688)
Query Neighborhood Hits	246	Target Neighborhood Hits	598	Shared Neighborhood Hits	45
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAD50_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.052452 (rank : 670)
Query Neighborhood Hits	246	Target Neighborhood Hits	1317	Shared Neighborhood Hits	60
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.055226 (rank : 601)
Query Neighborhood Hits	246	Target Neighborhood Hits	1366	Shared Neighborhood Hits	61
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAGE_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.070037 (rank : 355)
Query Neighborhood Hits	246	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RAGE_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.068095 (rank : 376)
Query Neighborhood Hits	246	Target Neighborhood Hits	295	Shared Neighborhood Hits	35
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RASA1_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.056151 (rank : 576)
Query Neighborhood Hits	246	Target Neighborhood Hits	258	Shared Neighborhood Hits	35
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RB6I2_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.053214 (rank : 647)
Query Neighborhood Hits	246	Target Neighborhood Hits	1584	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.056372 (rank : 569)
Query Neighborhood Hits	246	Target Neighborhood Hits	1433	Shared Neighborhood Hits	61
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBM25_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.057435 (rank : 532)
Query Neighborhood Hits	246	Target Neighborhood Hits	682	Shared Neighborhood Hits	40
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

REST_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.058938 (rank : 509)
Query Neighborhood Hits	246	Target Neighborhood Hits	1506	Shared Neighborhood Hits	64
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFIP3_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.062810 (rank : 436)
Query Neighborhood Hits	246	Target Neighborhood Hits	1055	Shared Neighborhood Hits	50
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP4_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.050590 (rank : 716)
Query Neighborhood Hits	246	Target Neighborhood Hits	785	Shared Neighborhood Hits	50
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RGNEF_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.061628 (rank : 460)
Query Neighborhood Hits	246	Target Neighborhood Hits	641	Shared Neighborhood Hits	39
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RHG04_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.151033 (rank : 138)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	108
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RILP_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.060079 (rank : 489)
Query Neighborhood Hits	246	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

ROBO4_MOUSE
θ value	θ > 10 (rank : 703)	NC score	0.115209 (rank : 206)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

RPGR1_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.055029 (rank : 609)
Query Neighborhood Hits	246	Target Neighborhood Hits	578	Shared Neighborhood Hits	37
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RPGR1_MOUSE
θ value	θ > 10 (rank : 705)	NC score	0.060515 (rank : 479)
Query Neighborhood Hits	246	Target Neighborhood Hits	713	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RUFY1_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.053410 (rank : 641)
Query Neighborhood Hits	246	Target Neighborhood Hits	765	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUSC1_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.139232 (rank : 151)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SAKS1_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.055060 (rank : 605)
Query Neighborhood Hits	246	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

SDCG8_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.055882 (rank : 587)
Query Neighborhood Hits	246	Target Neighborhood Hits	1002	Shared Neighborhood Hits	49
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SH21B_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.050437 (rank : 720)
Query Neighborhood Hits	246	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SHC3_MOUSE
θ value	θ > 10 (rank : 711)	NC score	0.050950 (rank : 707)
Query Neighborhood Hits	246	Target Neighborhood Hits	151	Shared Neighborhood Hits	29
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SLAP1_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.057435 (rank : 531)
Query Neighborhood Hits	246	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 713)	NC score	0.055386 (rank : 594)
Query Neighborhood Hits	246	Target Neighborhood Hits	117	Shared Neighborhood Hits	22
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.064041 (rank : 417)
Query Neighborhood Hits	246	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.064790 (rank : 408)
Query Neighborhood Hits	246	Target Neighborhood Hits	136	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SLY_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.072627 (rank : 334)
Query Neighborhood Hits	246	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.080551 (rank : 292)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SMC1A_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.050016 (rank : 731)
Query Neighborhood Hits	246	Target Neighborhood Hits	1346	Shared Neighborhood Hits	66
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC2_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.053520 (rank : 638)
Query Neighborhood Hits	246	Target Neighborhood Hits	1405	Shared Neighborhood Hits	62
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SNX18_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.193332 (rank : 100)
Query Neighborhood Hits	246	Target Neighborhood Hits	207	Shared Neighborhood Hits	87
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.192611 (rank : 101)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	85
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SN_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.058613 (rank : 516)
Query Neighborhood Hits	246	Target Neighborhood Hits	434	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

SN_MOUSE
θ value	θ > 10 (rank : 723)	NC score	0.061285 (rank : 466)
Query Neighborhood Hits	246	Target Neighborhood Hits	416	Shared Neighborhood Hits	34
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

SORL_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.065517 (rank : 402)
Query Neighborhood Hits	246	Target Neighborhood Hits	440	Shared Neighborhood Hits	50
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 725)	NC score	0.060345 (rank : 483)
Query Neighborhood Hits	246	Target Neighborhood Hits	439	Shared Neighborhood Hits	47
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPEG_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.052722 (rank : 663)
Query Neighborhood Hits	246	Target Neighborhood Hits	1762	Shared Neighborhood Hits	76
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPN90_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.086428 (rank : 270)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPN90_MOUSE
θ value	θ > 10 (rank : 728)	NC score	0.074632 (rank : 323)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPTA1_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.106251 (rank : 220)
Query Neighborhood Hits	246	Target Neighborhood Hits	748	Shared Neighborhood Hits	127
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 730)	NC score	0.102366 (rank : 228)
Query Neighborhood Hits	246	Target Neighborhood Hits	675	Shared Neighborhood Hits	124
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.115909 (rank : 203)
Query Neighborhood Hits	246	Target Neighborhood Hits	888	Shared Neighborhood Hits	132
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRC_MOUSE
θ value	θ > 10 (rank : 732)	NC score	0.063681 (rank : 422)
Query Neighborhood Hits	246	Target Neighborhood Hits	1033	Shared Neighborhood Hits	105
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRGP1_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.116014 (rank : 202)
Query Neighborhood Hits	246	Target Neighborhood Hits	390	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

STAC3_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.206321 (rank : 91)
Query Neighborhood Hits	246	Target Neighborhood Hits	228	Shared Neighborhood Hits	90
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 735)	NC score	0.205030 (rank : 92)
Query Neighborhood Hits	246	Target Neighborhood Hits	232	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_MOUSE
θ value	θ > 10 (rank : 736)	NC score	0.250107 (rank : 70)
Query Neighborhood Hits	246	Target Neighborhood Hits	268	Shared Neighborhood Hits	102
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STS1_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.076764 (rank : 311)
Query Neighborhood Hits	246	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS1_MOUSE
θ value	θ > 10 (rank : 738)	NC score	0.076139 (rank : 319)
Query Neighborhood Hits	246	Target Neighborhood Hits	104	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS2_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.100553 (rank : 230)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SWP70_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.054823 (rank : 612)
Query Neighborhood Hits	246	Target Neighborhood Hits	973	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYCP1_MOUSE
θ value	θ > 10 (rank : 741)	NC score	0.059976 (rank : 490)
Query Neighborhood Hits	246	Target Neighborhood Hits	1456	Shared Neighborhood Hits	62
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

T2_MOUSE
θ value	θ > 10 (rank : 742)	NC score	0.070378 (rank : 349)
Query Neighborhood Hits	246	Target Neighborhood Hits	140	Shared Neighborhood Hits	17
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

T3JAM_MOUSE
θ value	θ > 10 (rank : 743)	NC score	0.055953 (rank : 583)
Query Neighborhood Hits	246	Target Neighborhood Hits	535	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TARSH_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.070552 (rank : 347)
Query Neighborhood Hits	246	Target Neighborhood Hits	768	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TAXB1_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.057175 (rank : 542)
Query Neighborhood Hits	246	Target Neighborhood Hits	829	Shared Neighborhood Hits	49
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TCGAP_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.084358 (rank : 278)
Query Neighborhood Hits	246	Target Neighborhood Hits	872	Shared Neighborhood Hits	95
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 747)	NC score	0.093060 (rank : 245)
Query Neighborhood Hits	246	Target Neighborhood Hits	409	Shared Neighborhood Hits	87
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TENN_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.125393 (rank : 176)
Query Neighborhood Hits	246	Target Neighborhood Hits	453	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENX_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.097339 (rank : 236)
Query Neighborhood Hits	246	Target Neighborhood Hits	789	Shared Neighborhood Hits	55
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TEX9_MOUSE
θ value	θ > 10 (rank : 750)	NC score	0.057230 (rank : 539)
Query Neighborhood Hits	246	Target Neighborhood Hits	581	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TIAM1_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.076617 (rank : 314)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	21
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.077834 (rank : 305)
Query Neighborhood Hits	246	Target Neighborhood Hits	205	Shared Neighborhood Hits	19
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TMF1_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.064999 (rank : 407)
Query Neighborhood Hits	246	Target Neighborhood Hits	987	Shared Neighborhood Hits	52
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TMIGD_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.072726 (rank : 333)
Query Neighborhood Hits	246	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
θ value	θ > 10 (rank : 755)	NC score	0.073424 (rank : 329)
Query Neighborhood Hits	246	Target Neighborhood Hits	234	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TPM2_HUMAN
θ value	θ > 10 (rank : 756)	NC score	0.051998 (rank : 678)
Query Neighborhood Hits	246	Target Neighborhood Hits	677	Shared Neighborhood Hits	49
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
θ value	θ > 10 (rank : 757)	NC score	0.050944 (rank : 708)
Query Neighborhood Hits	246	Target Neighborhood Hits	676	Shared Neighborhood Hits	49
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM3_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.050380 (rank : 724)
Query Neighborhood Hits	246	Target Neighborhood Hits	689	Shared Neighborhood Hits	52
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TPM4_MOUSE
θ value	θ > 10 (rank : 759)	NC score	0.052428 (rank : 671)
Query Neighborhood Hits	246	Target Neighborhood Hits	703	Shared Neighborhood Hits	47
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TPR_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.055238 (rank : 600)
Query Neighborhood Hits	246	Target Neighborhood Hits	1921	Shared Neighborhood Hits	74
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRAIP_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.056473 (rank : 564)
Query Neighborhood Hits	246	Target Neighborhood Hits	780	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRHY_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.070087 (rank : 354)
Query Neighborhood Hits	246	Target Neighborhood Hits	1385	Shared Neighborhood Hits	67
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRIO_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.054781 (rank : 615)
Query Neighborhood Hits	246	Target Neighborhood Hits	1580	Shared Neighborhood Hits	115
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TRIPB_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.059465 (rank : 501)
Query Neighborhood Hits	246	Target Neighborhood Hits	1587	Shared Neighborhood Hits	73
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TUFT1_HUMAN
θ value	θ > 10 (rank : 765)	NC score	0.055887 (rank : 586)
Query Neighborhood Hits	246	Target Neighborhood Hits	686	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 766)	NC score	0.060950 (rank : 471)
Query Neighborhood Hits	246	Target Neighborhood Hits	732	Shared Neighborhood Hits	49
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

TXK_MOUSE
θ value	θ > 10 (rank : 767)	NC score	0.051998 (rank : 679)
Query Neighborhood Hits	246	Target Neighborhood Hits	980	Shared Neighborhood Hits	91
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TXLNA_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.051198 (rank : 697)
Query Neighborhood Hits	246	Target Neighborhood Hits	982	Shared Neighborhood Hits	50
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TYRO3_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.054806 (rank : 614)
Query Neighborhood Hits	246	Target Neighborhood Hits	995	Shared Neighborhood Hits	61
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.053375 (rank : 642)
Query Neighborhood Hits	246	Target Neighborhood Hits	1007	Shared Neighborhood Hits	63
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

U2AFM_MOUSE
θ value	θ > 10 (rank : 771)	NC score	0.057879 (rank : 524)
Query Neighborhood Hits	246	Target Neighborhood Hits	543	Shared Neighborhood Hits	41
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

UFO_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.051053 (rank : 702)
Query Neighborhood Hits	246	Target Neighborhood Hits	981	Shared Neighborhood Hits	63
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.052708 (rank : 665)
Query Neighborhood Hits	246	Target Neighborhood Hits	988	Shared Neighborhood Hits	69
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

VCAM1_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.064171 (rank : 416)
Query Neighborhood Hits	246	Target Neighborhood Hits	352	Shared Neighborhood Hits	33
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

VCAM1_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.066190 (rank : 396)
Query Neighborhood Hits	246	Target Neighborhood Hits	320	Shared Neighborhood Hits	32
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VSIG2_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.056507 (rank : 560)
Query Neighborhood Hits	246	Target Neighborhood Hits	321	Shared Neighborhood Hits	32
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG2_MOUSE
θ value	θ > 10 (rank : 777)	NC score	0.053051 (rank : 653)
Query Neighborhood Hits	246	Target Neighborhood Hits	316	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

XE7_HUMAN
θ value	θ > 10 (rank : 778)	NC score	0.070117 (rank : 352)
Query Neighborhood Hits	246	Target Neighborhood Hits	738	Shared Neighborhood Hits	50
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ZN291_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.066968 (rank : 387)
Query Neighborhood Hits	246	Target Neighborhood Hits	647	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

Hits sorted by NC score

RIMB2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	246	Target Neighborhood Hits	246	Shared Neighborhood Hits	246
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_HUMAN
NC score	0.970108 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	246	Target Neighborhood Hits	263	Shared Neighborhood Hits	172
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB1_HUMAN
NC score	0.562752 (rank : 3)	θ value	3.00075e-104 (rank : 4)
Query Neighborhood Hits	246	Target Neighborhood Hits	1479	Shared Neighborhood Hits	169
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
NC score	0.498115 (rank : 4)	θ value	1.58745e-113 (rank : 3)
Query Neighborhood Hits	246	Target Neighborhood Hits	1376	Shared Neighborhood Hits	169
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CD2AP_MOUSE
NC score	0.477154 (rank : 5)	θ value	1.9326e-10 (rank : 5)
Query Neighborhood Hits	246	Target Neighborhood Hits	336	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2AP_HUMAN
NC score	0.473106 (rank : 6)	θ value	1.25267e-09 (rank : 6)
Query Neighborhood Hits	246	Target Neighborhood Hits	315	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

SH3K1_HUMAN
NC score	0.457947 (rank : 7)	θ value	2.36244e-08 (rank : 8)
Query Neighborhood Hits	246	Target Neighborhood Hits	341	Shared Neighborhood Hits	118
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
NC score	0.454335 (rank : 8)	θ value	1.80886e-08 (rank : 7)
Query Neighborhood Hits	246	Target Neighborhood Hits	332	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SH3G3_MOUSE
NC score	0.386478 (rank : 9)	θ value	0.00035302 (rank : 28)
Query Neighborhood Hits	246	Target Neighborhood Hits	236	Shared Neighborhood Hits	121
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3G2_MOUSE
NC score	0.385642 (rank : 10)	θ value	0.000121331 (rank : 25)
Query Neighborhood Hits	246	Target Neighborhood Hits	319	Shared Neighborhood Hits	125
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G2_HUMAN
NC score	0.384415 (rank : 11)	θ value	0.00020696 (rank : 27)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	128
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G1_HUMAN
NC score	0.375375 (rank : 12)	θ value	7.1131e-05 (rank : 22)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	129
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G3_HUMAN
NC score	0.371189 (rank : 13)	θ value	0.00102713 (rank : 37)
Query Neighborhood Hits	246	Target Neighborhood Hits	222	Shared Neighborhood Hits	119
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G1_MOUSE
NC score	0.367647 (rank : 14)	θ value	0.00175202 (rank : 40)
Query Neighborhood Hits	246	Target Neighborhood Hits	291	Shared Neighborhood Hits	123
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

VINEX_HUMAN
NC score	0.362962 (rank : 15)	θ value	0.00228821 (rank : 50)
Query Neighborhood Hits	246	Target Neighborhood Hits	270	Shared Neighborhood Hits	110
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ABI2_MOUSE
NC score	0.356225 (rank : 16)	θ value	0.000602161 (rank : 31)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	105
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

VINEX_MOUSE
NC score	0.355514 (rank : 17)	θ value	0.00390308 (rank : 56)
Query Neighborhood Hits	246	Target Neighborhood Hits	286	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ABI2_HUMAN
NC score	0.350207 (rank : 18)	θ value	0.000602161 (rank : 30)
Query Neighborhood Hits	246	Target Neighborhood Hits	350	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

PACN1_HUMAN
NC score	0.345970 (rank : 19)	θ value	3.19293e-05 (rank : 17)
Query Neighborhood Hits	246	Target Neighborhood Hits	320	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
NC score	0.345825 (rank : 20)	θ value	3.19293e-05 (rank : 18)
Query Neighborhood Hits	246	Target Neighborhood Hits	283	Shared Neighborhood Hits	108
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

DNMBP_HUMAN
NC score	0.345314 (rank : 21)	θ value	1.69304e-06 (rank : 12)
Query Neighborhood Hits	246	Target Neighborhood Hits	413	Shared Neighborhood Hits	112
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PPIP1_MOUSE
NC score	0.337541 (rank : 22)	θ value	0.00102713 (rank : 36)
Query Neighborhood Hits	246	Target Neighborhood Hits	377	Shared Neighborhood Hits	122
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PACN2_HUMAN
NC score	0.336680 (rank : 23)	θ value	0.000602161 (rank : 32)
Query Neighborhood Hits	246	Target Neighborhood Hits	339	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

DNMBP_MOUSE
NC score	0.336307 (rank : 24)	θ value	7.1131e-05 (rank : 21)
Query Neighborhood Hits	246	Target Neighborhood Hits	435	Shared Neighborhood Hits	116
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SRBS1_MOUSE
NC score	0.331735 (rank : 25)	θ value	0.0736092 (rank : 111)
Query Neighborhood Hits	246	Target Neighborhood Hits	409	Shared Neighborhood Hits	114
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PPIP1_HUMAN
NC score	0.330443 (rank : 26)	θ value	0.00102713 (rank : 35)
Query Neighborhood Hits	246	Target Neighborhood Hits	389	Shared Neighborhood Hits	123
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SRBS1_HUMAN
NC score	0.328376 (rank : 27)	θ value	0.0563607 (rank : 108)
Query Neighborhood Hits	246	Target Neighborhood Hits	396	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

GRB2_MOUSE
NC score	0.323878 (rank : 28)	θ value	0.00228821 (rank : 44)
Query Neighborhood Hits	246	Target Neighborhood Hits	312	Shared Neighborhood Hits	116
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRB2_HUMAN
NC score	0.323746 (rank : 29)	θ value	0.00228821 (rank : 43)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	116
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

PACN2_MOUSE
NC score	0.321851 (rank : 30)	θ value	0.00228821 (rank : 46)
Query Neighborhood Hits	246	Target Neighborhood Hits	382	Shared Neighborhood Hits	117
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

ABI1_HUMAN
NC score	0.318582 (rank : 31)	θ value	0.0148317 (rank : 72)
Query Neighborhood Hits	246	Target Neighborhood Hits	257	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
NC score	0.316442 (rank : 32)	θ value	0.0736092 (rank : 109)
Query Neighborhood Hits	246	Target Neighborhood Hits	246	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

PACN3_HUMAN
NC score	0.313166 (rank : 33)	θ value	0.0431538 (rank : 95)
Query Neighborhood Hits	246	Target Neighborhood Hits	385	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

NCF2_HUMAN
NC score	0.311831 (rank : 34)	θ value	0.47712 (rank : 143)
Query Neighborhood Hits	246	Target Neighborhood Hits	229	Shared Neighborhood Hits	97
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

ARHG6_HUMAN
NC score	0.310738 (rank : 35)	θ value	0.00298849 (rank : 51)
Query Neighborhood Hits	246	Target Neighborhood Hits	376	Shared Neighborhood Hits	119
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
NC score	0.310634 (rank : 36)	θ value	0.00298849 (rank : 52)
Query Neighborhood Hits	246	Target Neighborhood Hits	394	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

PACN3_MOUSE
NC score	0.310116 (rank : 37)	θ value	0.0431538 (rank : 96)
Query Neighborhood Hits	246	Target Neighborhood Hits	380	Shared Neighborhood Hits	114
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

STAM1_HUMAN
NC score	0.309654 (rank : 38)	θ value	0.0252991 (rank : 81)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	118
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
NC score	0.308185 (rank : 39)	θ value	0.0330416 (rank : 94)
Query Neighborhood Hits	246	Target Neighborhood Hits	273	Shared Neighborhood Hits	119
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
NC score	0.307260 (rank : 40)	θ value	0.00134147 (rank : 39)
Query Neighborhood Hits	246	Target Neighborhood Hits	285	Shared Neighborhood Hits	113
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

ARHG7_HUMAN
NC score	0.302867 (rank : 41)	θ value	0.00665767 (rank : 57)
Query Neighborhood Hits	246	Target Neighborhood Hits	347	Shared Neighborhood Hits	117
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

NCF1_HUMAN
NC score	0.299714 (rank : 42)	θ value	0.00134147 (rank : 38)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	95
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

GRAP_MOUSE
NC score	0.297490 (rank : 43)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	246	Target Neighborhood Hits	309	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ARHG7_MOUSE
NC score	0.296890 (rank : 44)	θ value	0.0563607 (rank : 100)
Query Neighborhood Hits	246	Target Neighborhood Hits	396	Shared Neighborhood Hits	117
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

NCF1_MOUSE
NC score	0.294324 (rank : 45)	θ value	0.00869519 (rank : 67)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	102
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

STAM2_HUMAN
NC score	0.293828 (rank : 46)	θ value	0.0252991 (rank : 82)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	118
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

NCK1_HUMAN
NC score	0.293534 (rank : 47)	θ value	0.0148317 (rank : 75)
Query Neighborhood Hits	246	Target Neighborhood Hits	312	Shared Neighborhood Hits	107
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

SRC8_HUMAN
NC score	0.292885 (rank : 48)	θ value	0.163984 (rank : 120)
Query Neighborhood Hits	246	Target Neighborhood Hits	269	Shared Neighborhood Hits	113
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

NCK2_HUMAN
NC score	0.289985 (rank : 49)	θ value	0.0113563 (rank : 70)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	106
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

SRC8_MOUSE
NC score	0.286677 (rank : 50)	θ value	0.21417 (rank : 127)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	112
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

GRAP_HUMAN
NC score	0.285600 (rank : 51)	θ value	0.0148317 (rank : 74)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	113
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP2_MOUSE
NC score	0.277968 (rank : 52)	θ value	0.47712 (rank : 142)
Query Neighborhood Hits	246	Target Neighborhood Hits	297	Shared Neighborhood Hits	110
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP2_HUMAN
NC score	0.275220 (rank : 53)	θ value	0.279714 (rank : 132)
Query Neighborhood Hits	246	Target Neighborhood Hits	304	Shared Neighborhood Hits	111
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

VAV_MOUSE
NC score	0.269983 (rank : 54)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	246	Target Neighborhood Hits	430	Shared Neighborhood Hits	112
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

CRK_MOUSE
NC score	0.269316 (rank : 55)	θ value	0.21417 (rank : 124)
Query Neighborhood Hits	246	Target Neighborhood Hits	314	Shared Neighborhood Hits	112
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

VAV_HUMAN
NC score	0.268731 (rank : 56)	θ value	0.00228821 (rank : 48)
Query Neighborhood Hits	246	Target Neighborhood Hits	452	Shared Neighborhood Hits	110
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

OSTF1_HUMAN
NC score	0.267684 (rank : 57)	θ value	0.0252991 (rank : 79)
Query Neighborhood Hits	246	Target Neighborhood Hits	466	Shared Neighborhood Hits	112
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ITSN2_HUMAN
NC score	0.263938 (rank : 58)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	246	Target Neighborhood Hits	1173	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CRK_HUMAN
NC score	0.263327 (rank : 59)	θ value	0.21417 (rank : 123)
Query Neighborhood Hits	246	Target Neighborhood Hits	308	Shared Neighborhood Hits	112
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

OSTF1_MOUSE
NC score	0.258229 (rank : 60)	θ value	0.0330416 (rank : 90)
Query Neighborhood Hits	246	Target Neighborhood Hits	467	Shared Neighborhood Hits	114
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

HCLS1_HUMAN
NC score	0.257707 (rank : 61)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	104
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

STAC_HUMAN
NC score	0.256264 (rank : 62)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	246	Target Neighborhood Hits	276	Shared Neighborhood Hits	102
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

HCLS1_MOUSE
NC score	0.256213 (rank : 63)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	106
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

ITSN1_HUMAN
NC score	0.254738 (rank : 64)	θ value	0.000121331 (rank : 24)
Query Neighborhood Hits	246	Target Neighborhood Hits	1757	Shared Neighborhood Hits	161
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_MOUSE
NC score	0.253919 (rank : 65)	θ value	0.00228821 (rank : 45)
Query Neighborhood Hits	246	Target Neighborhood Hits	1371	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

CRKL_HUMAN
NC score	0.253789 (rank : 66)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	246	Target Neighborhood Hits	313	Shared Neighborhood Hits	111
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

ITSN1_MOUSE
NC score	0.253647 (rank : 67)	θ value	0.000461057 (rank : 29)
Query Neighborhood Hits	246	Target Neighborhood Hits	1669	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NCF4_MOUSE
NC score	0.252204 (rank : 68)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	93
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

CRKL_MOUSE
NC score	0.251241 (rank : 69)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	112
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

STAC_MOUSE
NC score	0.250107 (rank : 70)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	246	Target Neighborhood Hits	268	Shared Neighborhood Hits	102
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

FINC_MOUSE
NC score	0.248937 (rank : 71)	θ value	8.40245e-06 (rank : 14)
Query Neighborhood Hits	246	Target Neighborhood Hits	309	Shared Neighborhood Hits	58
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

CT032_HUMAN
NC score	0.247518 (rank : 72)	θ value	0.62314 (rank : 145)
Query Neighborhood Hits	246	Target Neighborhood Hits	235	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

VAV3_HUMAN
NC score	0.243137 (rank : 73)	θ value	0.000786445 (rank : 34)
Query Neighborhood Hits	246	Target Neighborhood Hits	398	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

AHI1_MOUSE
NC score	0.241652 (rank : 74)	θ value	9.29e-05 (rank : 23)
Query Neighborhood Hits	246	Target Neighborhood Hits	496	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

FINC_HUMAN
NC score	0.240984 (rank : 75)	θ value	5.44631e-05 (rank : 20)
Query Neighborhood Hits	246	Target Neighborhood Hits	302	Shared Neighborhood Hits	55
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

EFS_MOUSE
NC score	0.240133 (rank : 76)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	246	Target Neighborhood Hits	389	Shared Neighborhood Hits	100
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

VAV2_MOUSE
NC score	0.240056 (rank : 77)	θ value	0.21417 (rank : 129)
Query Neighborhood Hits	246	Target Neighborhood Hits	456	Shared Neighborhood Hits	115
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

AHI1_HUMAN
NC score	0.239686 (rank : 78)	θ value	0.000786445 (rank : 33)
Query Neighborhood Hits	246	Target Neighborhood Hits	537	Shared Neighborhood Hits	107
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

VAV2_HUMAN
NC score	0.238130 (rank : 79)	θ value	0.279714 (rank : 136)
Query Neighborhood Hits	246	Target Neighborhood Hits	453	Shared Neighborhood Hits	114
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ABI3_HUMAN
NC score	0.237755 (rank : 80)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	86
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

VAV3_MOUSE
NC score	0.236291 (rank : 81)	θ value	0.00298849 (rank : 53)
Query Neighborhood Hits	246	Target Neighborhood Hits	404	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

NCF4_HUMAN
NC score	0.235146 (rank : 82)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	246	Target Neighborhood Hits	161	Shared Neighborhood Hits	83
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ABI3_MOUSE
NC score	0.233960 (rank : 83)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

SHLB1_MOUSE
NC score	0.232795 (rank : 84)	θ value	0.0736092 (rank : 110)
Query Neighborhood Hits	246	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

EFS_HUMAN
NC score	0.230049 (rank : 85)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	246	Target Neighborhood Hits	348	Shared Neighborhood Hits	101
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

SHLB1_HUMAN
NC score	0.229422 (rank : 86)	θ value	0.0563607 (rank : 107)
Query Neighborhood Hits	246	Target Neighborhood Hits	96	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

BCAR1_HUMAN
NC score	0.215437 (rank : 87)	θ value	0.279714 (rank : 130)
Query Neighborhood Hits	246	Target Neighborhood Hits	554	Shared Neighborhood Hits	104
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
NC score	0.215348 (rank : 88)	θ value	1.06291 (rank : 158)
Query Neighborhood Hits	246	Target Neighborhood Hits	438	Shared Neighborhood Hits	103
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SNX9_HUMAN
NC score	0.211507 (rank : 89)	θ value	0.0252991 (rank : 80)
Query Neighborhood Hits	246	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

CASL_MOUSE
NC score	0.206910 (rank : 90)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	100
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

STAC3_HUMAN
NC score	0.206321 (rank : 91)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	246	Target Neighborhood Hits	228	Shared Neighborhood Hits	90
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
NC score	0.205030 (rank : 92)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	246	Target Neighborhood Hits	232	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CASL_HUMAN
NC score	0.203240 (rank : 93)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	246	Target Neighborhood Hits	259	Shared Neighborhood Hits	98
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

DBNL_HUMAN
NC score	0.199817 (rank : 94)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	246	Target Neighborhood Hits	244	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
NC score	0.197303 (rank : 95)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	246	Target Neighborhood Hits	306	Shared Neighborhood Hits	100
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

LASP1_HUMAN
NC score	0.196416 (rank : 96)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	246	Target Neighborhood Hits	293	Shared Neighborhood Hits	91
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

NEBL_HUMAN
NC score	0.196073 (rank : 97)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	246	Target Neighborhood Hits	457	Shared Neighborhood Hits	117
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

SNX9_MOUSE
NC score	0.196017 (rank : 98)	θ value	0.0330416 (rank : 93)
Query Neighborhood Hits	246	Target Neighborhood Hits	141	Shared Neighborhood Hits	69
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

LASP1_MOUSE
NC score	0.194595 (rank : 99)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	246	Target Neighborhood Hits	297	Shared Neighborhood Hits	91
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

SNX18_HUMAN
NC score	0.193332 (rank : 100)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	246	Target Neighborhood Hits	207	Shared Neighborhood Hits	87
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
NC score	0.192611 (rank : 101)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	85
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

NPHP1_HUMAN
NC score	0.190927 (rank : 102)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

SDK2_HUMAN
NC score	0.188449 (rank : 103)	θ value	2.44474e-05 (rank : 15)
Query Neighborhood Hits	246	Target Neighborhood Hits	495	Shared Neighborhood Hits	56
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NPHP1_MOUSE
NC score	0.183806 (rank : 104)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	246	Target Neighborhood Hits	267	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

FNDC3_HUMAN
NC score	0.183552 (rank : 105)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	246	Target Neighborhood Hits	196	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

SDK2_MOUSE
NC score	0.183282 (rank : 106)	θ value	0.00665767 (rank : 61)
Query Neighborhood Hits	246	Target Neighborhood Hits	480	Shared Neighborhood Hits	56
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

FNDC3_MOUSE
NC score	0.178130 (rank : 107)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	246	Target Neighborhood Hits	207	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

PTPRS_HUMAN
NC score	0.178075 (rank : 108)	θ value	1.99992e-07 (rank : 10)
Query Neighborhood Hits	246	Target Neighborhood Hits	472	Shared Neighborhood Hits	55
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

EM55_HUMAN
NC score	0.177372 (rank : 109)	θ value	0.00390308 (rank : 54)
Query Neighborhood Hits	246	Target Neighborhood Hits	228	Shared Neighborhood Hits	74
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

SDK1_HUMAN
NC score	0.176569 (rank : 110)	θ value	0.0193708 (rank : 77)
Query Neighborhood Hits	246	Target Neighborhood Hits	511	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

PTPRD_HUMAN
NC score	0.174049 (rank : 111)	θ value	1.17247e-07 (rank : 9)
Query Neighborhood Hits	246	Target Neighborhood Hits	485	Shared Neighborhood Hits	55
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

EM55_MOUSE
NC score	0.173480 (rank : 112)	θ value	0.00665767 (rank : 59)
Query Neighborhood Hits	246	Target Neighborhood Hits	221	Shared Neighborhood Hits	74
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

SDK1_MOUSE
NC score	0.173412 (rank : 113)	θ value	0.0431538 (rank : 99)
Query Neighborhood Hits	246	Target Neighborhood Hits	495	Shared Neighborhood Hits	55
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

RHG26_HUMAN
NC score	0.173101 (rank : 114)	θ value	0.0431538 (rank : 97)
Query Neighborhood Hits	246	Target Neighborhood Hits	281	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

PLCG1_MOUSE
NC score	0.173000 (rank : 115)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	246	Target Neighborhood Hits	314	Shared Neighborhood Hits	99
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

NEO1_MOUSE
NC score	0.172125 (rank : 116)	θ value	0.00390308 (rank : 55)
Query Neighborhood Hits	246	Target Neighborhood Hits	523	Shared Neighborhood Hits	52
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

SHAN2_MOUSE
NC score	0.171419 (rank : 117)	θ value	0.0330416 (rank : 92)
Query Neighborhood Hits	246	Target Neighborhood Hits	446	Shared Neighborhood Hits	80
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

PLCG2_HUMAN
NC score	0.171113 (rank : 118)	θ value	1.38821 (rank : 167)
Query Neighborhood Hits	246	Target Neighborhood Hits	280	Shared Neighborhood Hits	93
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

NEO1_HUMAN
NC score	0.169935 (rank : 119)	θ value	0.00665767 (rank : 60)
Query Neighborhood Hits	246	Target Neighborhood Hits	530	Shared Neighborhood Hits	52
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

PTPRD_MOUSE
NC score	0.169609 (rank : 120)	θ value	6.43352e-06 (rank : 13)
Query Neighborhood Hits	246	Target Neighborhood Hits	491	Shared Neighborhood Hits	56
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SHLB2_HUMAN
NC score	0.169314 (rank : 121)	θ value	0.813845 (rank : 154)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
NC score	0.169284 (rank : 122)	θ value	0.813845 (rank : 155)
Query Neighborhood Hits	246	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

ARHG9_MOUSE
NC score	0.168838 (rank : 123)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	246	Target Neighborhood Hits	234	Shared Neighborhood Hits	97
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG9_HUMAN
NC score	0.168594 (rank : 124)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	246	Target Neighborhood Hits	235	Shared Neighborhood Hits	97
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

PLCG1_HUMAN
NC score	0.167941 (rank : 125)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	246	Target Neighborhood Hits	293	Shared Neighborhood Hits	96
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PEX13_MOUSE
NC score	0.166955 (rank : 126)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	246	Target Neighborhood Hits	126	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

ARHG4_HUMAN
NC score	0.165881 (rank : 127)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	246	Target Neighborhood Hits	242	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

PTPRF_HUMAN
NC score	0.165616 (rank : 128)	θ value	5.81887e-07 (rank : 11)
Query Neighborhood Hits	246	Target Neighborhood Hits	489	Shared Neighborhood Hits	53
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

DCC_HUMAN
NC score	0.164959 (rank : 129)	θ value	0.0330416 (rank : 86)
Query Neighborhood Hits	246	Target Neighborhood Hits	583	Shared Neighborhood Hits	54
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

PEX13_HUMAN
NC score	0.162829 (rank : 130)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	246	Target Neighborhood Hits	128	Shared Neighborhood Hits	75
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

COCA1_MOUSE
NC score	0.161490 (rank : 131)	θ value	0.0330416 (rank : 85)
Query Neighborhood Hits	246	Target Neighborhood Hits	467	Shared Neighborhood Hits	57
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

DCC_MOUSE
NC score	0.159933 (rank : 132)	θ value	0.0330416 (rank : 87)
Query Neighborhood Hits	246	Target Neighborhood Hits	896	Shared Neighborhood Hits	62
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

TENR_HUMAN
NC score	0.156390 (rank : 133)	θ value	3.19293e-05 (rank : 19)
Query Neighborhood Hits	246	Target Neighborhood Hits	526	Shared Neighborhood Hits	52
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

NOXO1_MOUSE
NC score	0.155063 (rank : 134)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	246	Target Neighborhood Hits	114	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

DSCL1_HUMAN
NC score	0.154042 (rank : 135)	θ value	0.0961366 (rank : 113)
Query Neighborhood Hits	246	Target Neighborhood Hits	589	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

COCA1_HUMAN
NC score	0.153716 (rank : 136)	θ value	0.00869519 (rank : 62)
Query Neighborhood Hits	246	Target Neighborhood Hits	458	Shared Neighborhood Hits	54
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

TENR_MOUSE
NC score	0.153572 (rank : 137)	θ value	2.44474e-05 (rank : 16)
Query Neighborhood Hits	246	Target Neighborhood Hits	531	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

RHG04_HUMAN
NC score	0.151033 (rank : 138)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	108
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

MYO1F_HUMAN
NC score	0.150783 (rank : 139)	θ value	0.00869519 (rank : 66)
Query Neighborhood Hits	246	Target Neighborhood Hits	275	Shared Neighborhood Hits	113
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

NEBU_HUMAN
NC score	0.150337 (rank : 140)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	246	Target Neighborhood Hits	420	Shared Neighborhood Hits	100
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

MYO1F_MOUSE
NC score	0.147899 (rank : 141)	θ value	0.0563607 (rank : 105)
Query Neighborhood Hits	246	Target Neighborhood Hits	262	Shared Neighborhood Hits	115
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

IASPP_HUMAN
NC score	0.145662 (rank : 142)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	246	Target Neighborhood Hits	688	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ROBO1_HUMAN
NC score	0.144200 (rank : 143)	θ value	0.00869519 (rank : 68)
Query Neighborhood Hits	246	Target Neighborhood Hits	529	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ASPP2_HUMAN
NC score	0.142986 (rank : 144)	θ value	0.0330416 (rank : 83)
Query Neighborhood Hits	246	Target Neighborhood Hits	1156	Shared Neighborhood Hits	135
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ROBO3_MOUSE
NC score	0.142850 (rank : 145)	θ value	0.00228821 (rank : 47)
Query Neighborhood Hits	246	Target Neighborhood Hits	524	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ROBO1_MOUSE
NC score	0.141136 (rank : 146)	θ value	0.0431538 (rank : 98)
Query Neighborhood Hits	246	Target Neighborhood Hits	559	Shared Neighborhood Hits	53
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

TENN_MOUSE
NC score	0.140334 (rank : 147)	θ value	1.38821 (rank : 169)
Query Neighborhood Hits	246	Target Neighborhood Hits	484	Shared Neighborhood Hits	52
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MYOM1_HUMAN
NC score	0.140300 (rank : 148)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	246	Target Neighborhood Hits	405	Shared Neighborhood Hits	56
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

ARHG4_MOUSE
NC score	0.140093 (rank : 149)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	246	Target Neighborhood Hits	185	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

MPP6_HUMAN
NC score	0.139833 (rank : 150)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	246	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

RUSC1_HUMAN
NC score	0.139232 (rank : 151)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

ROBO2_MOUSE
NC score	0.138885 (rank : 152)	θ value	0.163984 (rank : 119)
Query Neighborhood Hits	246	Target Neighborhood Hits	504	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_HUMAN
NC score	0.138745 (rank : 153)	θ value	0.163984 (rank : 118)
Query Neighborhood Hits	246	Target Neighborhood Hits	479	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SRGP2_MOUSE
NC score	0.137875 (rank : 154)	θ value	0.62314 (rank : 149)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	102
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRGP2_HUMAN
NC score	0.137214 (rank : 155)	θ value	0.365318 (rank : 138)
Query Neighborhood Hits	246	Target Neighborhood Hits	331	Shared Neighborhood Hits	99
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

MPP6_MOUSE
NC score	0.135682 (rank : 156)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	246	Target Neighborhood Hits	187	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

ASPP1_MOUSE
NC score	0.135608 (rank : 157)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	246	Target Neighborhood Hits	1244	Shared Neighborhood Hits	129
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

IASPP_MOUSE
NC score	0.135021 (rank : 158)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	246	Target Neighborhood Hits	1024	Shared Neighborhood Hits	104
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MYOM1_MOUSE
NC score	0.134841 (rank : 159)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	246	Target Neighborhood Hits	415	Shared Neighborhood Hits	53
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

DSCAM_HUMAN
NC score	0.134750 (rank : 160)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	246	Target Neighborhood Hits	524	Shared Neighborhood Hits	52
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

CNTN3_HUMAN
NC score	0.133895 (rank : 161)	θ value	0.0330416 (rank : 84)
Query Neighborhood Hits	246	Target Neighborhood Hits	455	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

MPP2_MOUSE
NC score	0.133688 (rank : 162)	θ value	0.0961366 (rank : 114)
Query Neighborhood Hits	246	Target Neighborhood Hits	189	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MYOM2_HUMAN
NC score	0.132518 (rank : 163)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	246	Target Neighborhood Hits	341	Shared Neighborhood Hits	51
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NRCAM_HUMAN
NC score	0.132459 (rank : 164)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	246	Target Neighborhood Hits	439	Shared Neighborhood Hits	52
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

ROBO3_HUMAN
NC score	0.131378 (rank : 165)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	246	Target Neighborhood Hits	570	Shared Neighborhood Hits	54
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

ROBO4_HUMAN
NC score	0.131048 (rank : 166)	θ value	1.06291 (rank : 160)
Query Neighborhood Hits	246	Target Neighborhood Hits	364	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

RUSC1_MOUSE
NC score	0.130539 (rank : 167)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	246	Target Neighborhood Hits	206	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

CNTN3_MOUSE
NC score	0.130320 (rank : 168)	θ value	0.62314 (rank : 144)
Query Neighborhood Hits	246	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

ASPP1_HUMAN
NC score	0.129753 (rank : 169)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	246	Target Neighborhood Hits	956	Shared Neighborhood Hits	129
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MPP2_HUMAN
NC score	0.128554 (rank : 170)	θ value	0.279714 (rank : 134)
Query Neighborhood Hits	246	Target Neighborhood Hits	173	Shared Neighborhood Hits	57
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

ES8L3_MOUSE
NC score	0.127394 (rank : 171)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	246	Target Neighborhood Hits	168	Shared Neighborhood Hits	83
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

L1CAM_HUMAN
NC score	0.126589 (rank : 172)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	246	Target Neighborhood Hits	457	Shared Neighborhood Hits	55
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CNTN4_MOUSE
NC score	0.126010 (rank : 173)	θ value	0.279714 (rank : 131)
Query Neighborhood Hits	246	Target Neighborhood Hits	445	Shared Neighborhood Hits	53
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

COEA1_MOUSE
NC score	0.125999 (rank : 174)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	246	Target Neighborhood Hits	402	Shared Neighborhood Hits	55
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DDEF1_MOUSE
NC score	0.125928 (rank : 175)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	246	Target Neighborhood Hits	592	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

TENN_HUMAN
NC score	0.125393 (rank : 176)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	246	Target Neighborhood Hits	453	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

DDEF2_MOUSE
NC score	0.125214 (rank : 177)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	246	Target Neighborhood Hits	625	Shared Neighborhood Hits	98
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CHL1_HUMAN
NC score	0.124636 (rank : 178)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	246	Target Neighborhood Hits	413	Shared Neighborhood Hits	50
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

PUNC_MOUSE
NC score	0.124244 (rank : 179)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	246	Target Neighborhood Hits	501	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

CNTN4_HUMAN
NC score	0.124170 (rank : 180)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	246	Target Neighborhood Hits	449	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

PUNC_HUMAN
NC score	0.124139 (rank : 181)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	246	Target Neighborhood Hits	449	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

MYO1E_HUMAN
NC score	0.123920 (rank : 182)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	246	Target Neighborhood Hits	293	Shared Neighborhood Hits	110
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

SHAN1_HUMAN
NC score	0.123707 (rank : 183)	θ value	0.0330416 (rank : 91)
Query Neighborhood Hits	246	Target Neighborhood Hits	1041	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

CNTN6_MOUSE
NC score	0.123434 (rank : 184)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	246	Target Neighborhood Hits	429	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

NRCAM_MOUSE
NC score	0.122793 (rank : 185)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	246	Target Neighborhood Hits	432	Shared Neighborhood Hits	49
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

L1CAM_MOUSE
NC score	0.122501 (rank : 186)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	246	Target Neighborhood Hits	457	Shared Neighborhood Hits	55
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

COEA1_HUMAN
NC score	0.121993 (rank : 187)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	246	Target Neighborhood Hits	427	Shared Neighborhood Hits	57
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

NFASC_HUMAN
NC score	0.121725 (rank : 188)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	246	Target Neighborhood Hits	497	Shared Neighborhood Hits	52
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

DDEF2_HUMAN
NC score	0.120987 (rank : 189)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	246	Target Neighborhood Hits	599	Shared Neighborhood Hits	103
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CNTN6_HUMAN
NC score	0.120165 (rank : 190)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	246	Target Neighborhood Hits	422	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

PTPRB_HUMAN
NC score	0.119700 (rank : 191)	θ value	0.0563607 (rank : 106)
Query Neighborhood Hits	246	Target Neighborhood Hits	242	Shared Neighborhood Hits	47
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

USH2A_HUMAN
NC score	0.119022 (rank : 192)	θ value	1.81305 (rank : 180)
Query Neighborhood Hits	246	Target Neighborhood Hits	600	Shared Neighborhood Hits	55
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

CNTN1_HUMAN
NC score	0.118144 (rank : 193)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	246	Target Neighborhood Hits	431	Shared Neighborhood Hits	50
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

NFASC_MOUSE
NC score	0.118003 (rank : 194)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	246	Target Neighborhood Hits	475	Shared Neighborhood Hits	55
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

CNTN2_HUMAN
NC score	0.117524 (rank : 195)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	246	Target Neighborhood Hits	440	Shared Neighborhood Hits	51
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

ANM2_HUMAN
NC score	0.116973 (rank : 196)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	246	Target Neighborhood Hits	175	Shared Neighborhood Hits	86
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

MYPC3_MOUSE
NC score	0.116946 (rank : 197)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

CNTN5_MOUSE
NC score	0.116702 (rank : 198)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	246	Target Neighborhood Hits	434	Shared Neighborhood Hits	50
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

MYPC3_HUMAN
NC score	0.116342 (rank : 199)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	246	Target Neighborhood Hits	318	Shared Neighborhood Hits	51
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

CNTN1_MOUSE
NC score	0.116266 (rank : 200)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	246	Target Neighborhood Hits	422	Shared Neighborhood Hits	49
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_MOUSE
NC score	0.116079 (rank : 201)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	246	Target Neighborhood Hits	450	Shared Neighborhood Hits	50
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

SRGP1_HUMAN
NC score	0.116014 (rank : 202)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	246	Target Neighborhood Hits	390	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SPTA2_HUMAN
NC score	0.115909 (rank : 203)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	246	Target Neighborhood Hits	888	Shared Neighborhood Hits	132
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

COKA1_HUMAN
NC score	0.115764 (rank : 204)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	246	Target Neighborhood Hits	403	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CNTN5_HUMAN
NC score	0.115267 (rank : 205)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	246	Target Neighborhood Hits	446	Shared Neighborhood Hits	50
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

ROBO4_MOUSE
NC score	0.115209 (rank : 206)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

CHL1_MOUSE
NC score	0.114280 (rank : 207)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	246	Target Neighborhood Hits	402	Shared Neighborhood Hits	49
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

MPP3_MOUSE
NC score	0.114108 (rank : 208)	θ value	0.00869519 (rank : 65)
Query Neighborhood Hits	246	Target Neighborhood Hits	165	Shared Neighborhood Hits	32
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP3_HUMAN
NC score	0.113116 (rank : 209)	θ value	0.0252991 (rank : 78)
Query Neighborhood Hits	246	Target Neighborhood Hits	171	Shared Neighborhood Hits	33
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MYPC2_MOUSE
NC score	0.112380 (rank : 210)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	246	Target Neighborhood Hits	297	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

TENA_MOUSE
NC score	0.112312 (rank : 211)	θ value	0.00175202 (rank : 41)
Query Neighborhood Hits	246	Target Neighborhood Hits	596	Shared Neighborhood Hits	50
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

USH2A_MOUSE
NC score	0.112020 (rank : 212)	θ value	0.163984 (rank : 121)
Query Neighborhood Hits	246	Target Neighborhood Hits	626	Shared Neighborhood Hits	55
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

FNBP2_HUMAN
NC score	0.111358 (rank : 213)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	246	Target Neighborhood Hits	432	Shared Neighborhood Hits	104
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

MYPC2_HUMAN
NC score	0.110308 (rank : 214)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	246	Target Neighborhood Hits	316	Shared Neighborhood Hits	51
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

BOC_HUMAN
NC score	0.108438 (rank : 215)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	246	Target Neighborhood Hits	543	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

ANM2_MOUSE
NC score	0.108375 (rank : 216)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	246	Target Neighborhood Hits	175	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

CDON_MOUSE
NC score	0.108066 (rank : 217)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	246	Target Neighborhood Hits	410	Shared Neighborhood Hits	49
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

MPP4_MOUSE
NC score	0.107618 (rank : 218)	θ value	1.38821 (rank : 166)
Query Neighborhood Hits	246	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

CDON_HUMAN
NC score	0.106815 (rank : 219)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	246	Target Neighborhood Hits	412	Shared Neighborhood Hits	48
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

SPTA1_HUMAN
NC score	0.106251 (rank : 220)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	246	Target Neighborhood Hits	748	Shared Neighborhood Hits	127
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

BOC_MOUSE
NC score	0.106190 (rank : 221)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	246	Target Neighborhood Hits	433	Shared Neighborhood Hits	50
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

TENA_HUMAN
NC score	0.104507 (rank : 222)	θ value	0.813845 (rank : 156)
Query Neighborhood Hits	246	Target Neighborhood Hits	631	Shared Neighborhood Hits	52
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

MYPC1_HUMAN
NC score	0.103710 (rank : 223)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	246	Target Neighborhood Hits	303	Shared Neighborhood Hits	50
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

ES8L3_HUMAN
NC score	0.103347 (rank : 224)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	246	Target Neighborhood Hits	206	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ES8L2_MOUSE
NC score	0.103222 (rank : 225)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	246	Target Neighborhood Hits	169	Shared Neighborhood Hits	77
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

NOXO1_HUMAN
NC score	0.102818 (rank : 226)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	246	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

ARHG5_HUMAN
NC score	0.102400 (rank : 227)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	246	Target Neighborhood Hits	172	Shared Neighborhood Hits	60
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

SPTA1_MOUSE
NC score	0.102366 (rank : 228)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	246	Target Neighborhood Hits	675	Shared Neighborhood Hits	124
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

NPHN_HUMAN
NC score	0.101584 (rank : 229)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	246	Target Neighborhood Hits	362	Shared Neighborhood Hits	49
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

STS2_HUMAN
NC score	0.100553 (rank : 230)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

NCAM2_MOUSE
NC score	0.100424 (rank : 231)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	246	Target Neighborhood Hits	472	Shared Neighborhood Hits	49
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

ES8L2_HUMAN
NC score	0.100418 (rank : 232)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	246	Target Neighborhood Hits	193	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

NGEF_MOUSE
NC score	0.100029 (rank : 233)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	246	Target Neighborhood Hits	228	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

OBSL1_HUMAN
NC score	0.097454 (rank : 234)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	246	Target Neighborhood Hits	354	Shared Neighborhood Hits	34
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

MPP5_HUMAN
NC score	0.097428 (rank : 235)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	246	Target Neighborhood Hits	231	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

TENX_HUMAN
NC score	0.097339 (rank : 236)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	246	Target Neighborhood Hits	789	Shared Neighborhood Hits	55
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NCAM2_HUMAN
NC score	0.097332 (rank : 237)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	246	Target Neighborhood Hits	441	Shared Neighborhood Hits	48
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

CO7A1_HUMAN
NC score	0.096990 (rank : 238)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	246	Target Neighborhood Hits	807	Shared Neighborhood Hits	55
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MPP5_MOUSE
NC score	0.096878 (rank : 239)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

CIP4_HUMAN
NC score	0.096843 (rank : 240)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	246	Target Neighborhood Hits	374	Shared Neighborhood Hits	57
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

NGEF_HUMAN
NC score	0.096816 (rank : 241)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	246	Target Neighborhood Hits	166	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NPHN_MOUSE
NC score	0.096390 (rank : 242)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	246	Target Neighborhood Hits	370	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

ITB4_HUMAN
NC score	0.096204 (rank : 243)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	246	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

TITIN_HUMAN
NC score	0.094109 (rank : 244)	θ value	0.00175202 (rank : 42)
Query Neighborhood Hits	246	Target Neighborhood Hits	2923	Shared Neighborhood Hits	115
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TCGAP_MOUSE
NC score	0.093060 (rank : 245)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	246	Target Neighborhood Hits	409	Shared Neighborhood Hits	87
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

NCA11_MOUSE
NC score	0.092364 (rank : 246)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	246	Target Neighborhood Hits	661	Shared Neighborhood Hits	51
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

M3KL4_HUMAN
NC score	0.092348 (rank : 247)	θ value	0.0330416 (rank : 89)
Query Neighborhood Hits	246	Target Neighborhood Hits	1087	Shared Neighborhood Hits	123
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

NCA11_HUMAN
NC score	0.091667 (rank : 248)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	246	Target Neighborhood Hits	443	Shared Neighborhood Hits	45
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

FGR_HUMAN
NC score	0.090790 (rank : 249)	θ value	0.0330416 (rank : 88)
Query Neighborhood Hits	246	Target Neighborhood Hits	1067	Shared Neighborhood Hits	120
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

NCA12_MOUSE
NC score	0.090601 (rank : 250)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	246	Target Neighborhood Hits	399	Shared Neighborhood Hits	44
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

GLE1_HUMAN
NC score	0.090084 (rank : 251)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	246	Target Neighborhood Hits	445	Shared Neighborhood Hits	37
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

I12R2_HUMAN
NC score	0.089420 (rank : 252)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	246	Target Neighborhood Hits	163	Shared Neighborhood Hits	44
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

AMPH_HUMAN
NC score	0.089379 (rank : 253)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	246	Target Neighborhood Hits	455	Shared Neighborhood Hits	66
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

IL6RB_HUMAN
NC score	0.089137 (rank : 254)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	246	Target Neighborhood Hits	181	Shared Neighborhood Hits	43
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

MYPN_HUMAN
NC score	0.088996 (rank : 255)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	246	Target Neighborhood Hits	418	Shared Neighborhood Hits	37
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

PPIP2_HUMAN
NC score	0.088935 (rank : 256)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	246	Target Neighborhood Hits	254	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

FGRL1_HUMAN
NC score	0.088870 (rank : 257)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	246	Target Neighborhood Hits	335	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

PTPRV_MOUSE
NC score	0.088784 (rank : 258)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	38
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

IL6RB_MOUSE
NC score	0.088292 (rank : 259)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	246	Target Neighborhood Hits	168	Shared Neighborhood Hits	44
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

NCA12_HUMAN
NC score	0.088198 (rank : 260)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	246	Target Neighborhood Hits	437	Shared Neighborhood Hits	45
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

PTPRM_MOUSE
NC score	0.088056 (rank : 261)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	246	Target Neighborhood Hits	238	Shared Neighborhood Hits	47
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

MYPN_MOUSE
NC score	0.087872 (rank : 262)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	246	Target Neighborhood Hits	421	Shared Neighborhood Hits	38
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

MYOTI_MOUSE
NC score	0.087612 (rank : 263)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	246	Target Neighborhood Hits	297	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

PTPRM_HUMAN
NC score	0.087597 (rank : 264)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	246	Target Neighborhood Hits	244	Shared Neighborhood Hits	46
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

M3K11_HUMAN
NC score	0.087455 (rank : 265)	θ value	0.279714 (rank : 133)
Query Neighborhood Hits	246	Target Neighborhood Hits	1136	Shared Neighborhood Hits	122
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

GLE1_MOUSE
NC score	0.087318 (rank : 266)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	246	Target Neighborhood Hits	504	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

BI2L1_HUMAN
NC score	0.086926 (rank : 267)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

FGRL1_MOUSE
NC score	0.086694 (rank : 268)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	246	Target Neighborhood Hits	325	Shared Neighborhood Hits	33
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

MYOTI_HUMAN
NC score	0.086513 (rank : 269)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

SPN90_HUMAN
NC score	0.086428 (rank : 270)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

I12R2_MOUSE
NC score	0.085636 (rank : 271)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	246	Target Neighborhood Hits	143	Shared Neighborhood Hits	44
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

PTPRT_MOUSE
NC score	0.085426 (rank : 272)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	246	Target Neighborhood Hits	219	Shared Neighborhood Hits	47
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.085067 (rank : 273)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	246	Target Neighborhood Hits	217	Shared Neighborhood Hits	46
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

LIFR_HUMAN
NC score	0.084942 (rank : 274)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	246	Target Neighborhood Hits	130	Shared Neighborhood Hits	39
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LIFR_MOUSE
NC score	0.084930 (rank : 275)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	246	Target Neighborhood Hits	127	Shared Neighborhood Hits	38
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

PPIP2_MOUSE
NC score	0.084625 (rank : 276)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	246	Target Neighborhood Hits	308	Shared Neighborhood Hits	38
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PKHG1_HUMAN
NC score	0.084593 (rank : 277)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	246	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

TCGAP_HUMAN
NC score	0.084358 (rank : 278)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	246	Target Neighborhood Hits	872	Shared Neighborhood Hits	95
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

P85A_MOUSE
NC score	0.083392 (rank : 279)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	246	Target Neighborhood Hits	435	Shared Neighborhood Hits	77
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

EPS8_HUMAN
NC score	0.082713 (rank : 280)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	246	Target Neighborhood Hits	151	Shared Neighborhood Hits	66
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

KALM_HUMAN
NC score	0.082557 (rank : 281)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	246	Target Neighborhood Hits	114	Shared Neighborhood Hits	33
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

MALT1_HUMAN
NC score	0.082383 (rank : 282)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	246	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

PTPRJ_HUMAN
NC score	0.081920 (rank : 283)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	246	Target Neighborhood Hits	207	Shared Neighborhood Hits	36
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

EPS8_MOUSE
NC score	0.081723 (rank : 284)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

FGR_MOUSE
NC score	0.081712 (rank : 285)	θ value	0.0563607 (rank : 103)
Query Neighborhood Hits	246	Target Neighborhood Hits	1069	Shared Neighborhood Hits	117
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

P85A_HUMAN
NC score	0.081543 (rank : 286)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	246	Target Neighborhood Hits	479	Shared Neighborhood Hits	82
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PTPRJ_MOUSE
NC score	0.081428 (rank : 287)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	246	Target Neighborhood Hits	188	Shared Neighborhood Hits	34
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

SRC_HUMAN
NC score	0.081237 (rank : 288)	θ value	1.06291 (rank : 161)
Query Neighborhood Hits	246	Target Neighborhood Hits	1058	Shared Neighborhood Hits	117
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

CP250_MOUSE
NC score	0.081081 (rank : 289)	θ value	0.0193708 (rank : 76)
Query Neighborhood Hits	246	Target Neighborhood Hits	1583	Shared Neighborhood Hits	68
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MPP4_HUMAN
NC score	0.081045 (rank : 290)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	246	Target Neighborhood Hits	205	Shared Neighborhood Hits	44
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

BTK_HUMAN
NC score	0.080611 (rank : 291)	θ value	0.00665767 (rank : 58)
Query Neighborhood Hits	246	Target Neighborhood Hits	1026	Shared Neighborhood Hits	113
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

SLY_MOUSE
NC score	0.080551 (rank : 292)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

PTPRU_HUMAN
NC score	0.080472 (rank : 293)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	246	Target Neighborhood Hits	237	Shared Neighborhood Hits	46
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

ARHG3_HUMAN
NC score	0.080384 (rank : 294)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	246	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
NC score	0.080305 (rank : 295)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

YES_MOUSE
NC score	0.080056 (rank : 296)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	246	Target Neighborhood Hits	1052	Shared Neighborhood Hits	119
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ARHGG_MOUSE
NC score	0.079701 (rank : 297)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	246	Target Neighborhood Hits	152	Shared Neighborhood Hits	36
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

YES_HUMAN
NC score	0.079643 (rank : 298)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	246	Target Neighborhood Hits	1059	Shared Neighborhood Hits	120
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

FYN_MOUSE
NC score	0.079192 (rank : 299)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	246	Target Neighborhood Hits	1073	Shared Neighborhood Hits	116
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

AMPH_MOUSE
NC score	0.079097 (rank : 300)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	246	Target Neighborhood Hits	291	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

CP250_HUMAN
NC score	0.078966 (rank : 301)	θ value	0.00869519 (rank : 63)
Query Neighborhood Hits	246	Target Neighborhood Hits	1805	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MYBPH_MOUSE
NC score	0.078671 (rank : 302)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	246	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

FYN_HUMAN
NC score	0.077957 (rank : 303)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	246	Target Neighborhood Hits	1078	Shared Neighborhood Hits	117
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

KAZD1_MOUSE
NC score	0.077933 (rank : 304)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	246	Target Neighborhood Hits	281	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

TIAM1_MOUSE
NC score	0.077834 (rank : 305)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	246	Target Neighborhood Hits	205	Shared Neighborhood Hits	19
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

MCF2L_MOUSE
NC score	0.077726 (rank : 306)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	246	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

BTK_MOUSE
NC score	0.077648 (rank : 307)	θ value	0.0148317 (rank : 73)
Query Neighborhood Hits	246	Target Neighborhood Hits	1017	Shared Neighborhood Hits	110
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

ES8L1_MOUSE
NC score	0.077504 (rank : 308)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	246	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

PREX1_HUMAN
NC score	0.077135 (rank : 309)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

KAZD1_HUMAN
NC score	0.076978 (rank : 310)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	246	Target Neighborhood Hits	248	Shared Neighborhood Hits	32
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

STS1_HUMAN
NC score	0.076764 (rank : 311)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	246	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

MAMC1_MOUSE
NC score	0.076763 (rank : 312)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	246	Target Neighborhood Hits	357	Shared Neighborhood Hits	33
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

BIN1_MOUSE
NC score	0.076725 (rank : 313)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	246	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

TIAM1_HUMAN
NC score	0.076617 (rank : 314)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	21
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

MYBPH_HUMAN
NC score	0.076608 (rank : 315)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	246	Target Neighborhood Hits	256	Shared Neighborhood Hits	42
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MAMC1_HUMAN
NC score	0.076499 (rank : 316)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	246	Target Neighborhood Hits	357	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

M3K9_HUMAN
NC score	0.076443 (rank : 317)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	246	Target Neighborhood Hits	1123	Shared Neighborhood Hits	112
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

BIN1_HUMAN
NC score	0.076257 (rank : 318)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	246	Target Neighborhood Hits	335	Shared Neighborhood Hits	58
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

STS1_MOUSE
NC score	0.076139 (rank : 319)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	246	Target Neighborhood Hits	104	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

CT075_HUMAN
NC score	0.076132 (rank : 320)	θ value	0.0961366 (rank : 112)
Query Neighborhood Hits	246	Target Neighborhood Hits	387	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

ARHG8_MOUSE
NC score	0.076125 (rank : 321)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	246	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ES8L1_HUMAN
NC score	0.074980 (rank : 322)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	246	Target Neighborhood Hits	162	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

SPN90_MOUSE
NC score	0.074632 (rank : 323)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

MDGA1_HUMAN
NC score	0.074548 (rank : 324)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

INVO_HUMAN
NC score	0.074419 (rank : 325)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	246	Target Neighborhood Hits	636	Shared Neighborhood Hits	44
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

AZI1_HUMAN
NC score	0.073538 (rank : 326)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	246	Target Neighborhood Hits	1000	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

INCE_HUMAN
NC score	0.073485 (rank : 327)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	246	Target Neighborhood Hits	978	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

PTPRK_MOUSE
NC score	0.073483 (rank : 328)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	246	Target Neighborhood Hits	223	Shared Neighborhood Hits	46
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

TMIGD_MOUSE
NC score	0.073424 (rank : 329)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	246	Target Neighborhood Hits	234	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

IBP7_MOUSE
NC score	0.073338 (rank : 330)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	246	Target Neighborhood Hits	230	Shared Neighborhood Hits	32
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

LZTS2_MOUSE
NC score	0.073065 (rank : 331)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	246	Target Neighborhood Hits	423	Shared Neighborhood Hits	34
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

KIRR2_HUMAN
NC score	0.072916 (rank : 332)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	246	Target Neighborhood Hits	321	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

TMIGD_HUMAN
NC score	0.072726 (rank : 333)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	246	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

SLY_HUMAN
NC score	0.072627 (rank : 334)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	246	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

JAM3_HUMAN
NC score	0.072582 (rank : 335)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

PTPRK_HUMAN
NC score	0.072576 (rank : 336)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	246	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PCNT_HUMAN
NC score	0.072488 (rank : 337)	θ value	0.279714 (rank : 135)
Query Neighborhood Hits	246	Target Neighborhood Hits	1551	Shared Neighborhood Hits	78
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CSF3R_HUMAN
NC score	0.072341 (rank : 338)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	246	Target Neighborhood Hits	140	Shared Neighborhood Hits	45
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

PTPRO_HUMAN
NC score	0.071811 (rank : 339)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	246	Target Neighborhood Hits	139	Shared Neighborhood Hits	30
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

KIRR2_MOUSE
NC score	0.071612 (rank : 340)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	246	Target Neighborhood Hits	326	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

REST_HUMAN
NC score	0.071360 (rank : 341)	θ value	0.0113563 (rank : 71)
Query Neighborhood Hits	246	Target Neighborhood Hits	1605	Shared Neighborhood Hits	72
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

P85B_HUMAN
NC score	0.071216 (rank : 342)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	246	Target Neighborhood Hits	543	Shared Neighborhood Hits	64
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

LRC45_MOUSE
NC score	0.071048 (rank : 343)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	246	Target Neighborhood Hits	959	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

K0552_HUMAN
NC score	0.070924 (rank : 344)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	246	Target Neighborhood Hits	442	Shared Neighborhood Hits	36
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

M3K10_HUMAN
NC score	0.070823 (rank : 345)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	246	Target Neighborhood Hits	1071	Shared Neighborhood Hits	111
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

NEGR1_HUMAN
NC score	0.070638 (rank : 346)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	246	Target Neighborhood Hits	346	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

TARSH_HUMAN
NC score	0.070552 (rank : 347)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	246	Target Neighborhood Hits	768	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CE290_HUMAN
NC score	0.070418 (rank : 348)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	246	Target Neighborhood Hits	1553	Shared Neighborhood Hits	65
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

T2_MOUSE
NC score	0.070378 (rank : 349)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	246	Target Neighborhood Hits	140	Shared Neighborhood Hits	17
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

PTN11_MOUSE
NC score	0.070296 (rank : 350)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.070295 (rank : 351)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

XE7_HUMAN
NC score	0.070117 (rank : 352)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	246	Target Neighborhood Hits	738	Shared Neighborhood Hits	50
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

AZI1_MOUSE
NC score	0.070101 (rank : 353)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	246	Target Neighborhood Hits	990	Shared Neighborhood Hits	62
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

TRHY_HUMAN
NC score	0.070087 (rank : 354)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	246	Target Neighborhood Hits	1385	Shared Neighborhood Hits	67
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

RAGE_HUMAN
NC score	0.070037 (rank : 355)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	246	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

LSAMP_MOUSE
NC score	0.069942 (rank : 356)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	246	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

CCD21_MOUSE
NC score	0.069859 (rank : 357)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	246	Target Neighborhood Hits	1135	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

DOCK1_HUMAN
NC score	0.069836 (rank : 358)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	246	Target Neighborhood Hits	191	Shared Neighborhood Hits	74
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

ARHG8_HUMAN
NC score	0.069708 (rank : 359)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

MAG_MOUSE
NC score	0.069527 (rank : 360)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

NPTN_MOUSE
NC score	0.069447 (rank : 361)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	246	Target Neighborhood Hits	216	Shared Neighborhood Hits	32
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

ARHGA_MOUSE
NC score	0.069405 (rank : 362)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	246	Target Neighborhood Hits	125	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

NEGR1_MOUSE
NC score	0.069192 (rank : 363)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	246	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

P85B_MOUSE
NC score	0.069180 (rank : 364)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	246	Target Neighborhood Hits	519	Shared Neighborhood Hits	68
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

FSTL5_MOUSE
NC score	0.069172 (rank : 365)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	246	Target Neighborhood Hits	355	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

LSAMP_HUMAN
NC score	0.069101 (rank : 366)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	246	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

FSTL4_MOUSE
NC score	0.069083 (rank : 367)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	246	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

INCE_MOUSE
NC score	0.069070 (rank : 368)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	246	Target Neighborhood Hits	903	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

NPTN_HUMAN
NC score	0.069047 (rank : 369)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	246	Target Neighborhood Hits	212	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

CCD21_HUMAN
NC score	0.068989 (rank : 370)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	246	Target Neighborhood Hits	1228	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MUC18_HUMAN
NC score	0.068953 (rank : 371)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	246	Target Neighborhood Hits	275	Shared Neighborhood Hits	34
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

MAG_HUMAN
NC score	0.068802 (rank : 372)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	246	Target Neighborhood Hits	278	Shared Neighborhood Hits	32
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

FSTL5_HUMAN
NC score	0.068672 (rank : 373)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	246	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

OPCM_HUMAN
NC score	0.068282 (rank : 374)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	246	Target Neighborhood Hits	332	Shared Neighborhood Hits	33
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

CCHCR_HUMAN
NC score	0.068269 (rank : 375)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	246	Target Neighborhood Hits	717	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

RAGE_MOUSE
NC score	0.068095 (rank : 376)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	246	Target Neighborhood Hits	295	Shared Neighborhood Hits	35
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

ARHGG_HUMAN
NC score	0.068051 (rank : 377)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	246	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGA_HUMAN
NC score	0.067839 (rank : 378)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	246	Target Neighborhood Hits	187	Shared Neighborhood Hits	24
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

PTN6_MOUSE
NC score	0.067810 (rank : 379)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	33
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN6_HUMAN
NC score	0.067687 (rank : 380)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	246	Target Neighborhood Hits	234	Shared Neighborhood Hits	33
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

JAM3_MOUSE
NC score	0.067581 (rank : 381)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	246	Target Neighborhood Hits	286	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

GOGA1_HUMAN
NC score	0.067442 (rank : 382)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	246	Target Neighborhood Hits	1222	Shared Neighborhood Hits	58
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOG8A_HUMAN
NC score	0.067335 (rank : 383)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	246	Target Neighborhood Hits	635	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

FSTL4_HUMAN
NC score	0.067161 (rank : 384)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	246	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

LZTS2_HUMAN
NC score	0.067124 (rank : 385)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	246	Target Neighborhood Hits	427	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

ICAM5_MOUSE
NC score	0.067070 (rank : 386)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	246	Target Neighborhood Hits	308	Shared Neighborhood Hits	31
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

ZN291_HUMAN
NC score	0.066968 (rank : 387)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	246	Target Neighborhood Hits	647	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

IBP7_HUMAN
NC score	0.066946 (rank : 388)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	246	Target Neighborhood Hits	220	Shared Neighborhood Hits	29
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

ING3_MOUSE
NC score	0.066785 (rank : 389)	θ value	0.0113563 (rank : 69)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

NRG2_HUMAN
NC score	0.066675 (rank : 390)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	246	Target Neighborhood Hits	419	Shared Neighborhood Hits	40
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

SMC3_MOUSE
NC score	0.066658 (rank : 391)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	246	Target Neighborhood Hits	1187	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

GOGA2_HUMAN
NC score	0.066517 (rank : 392)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	246	Target Neighborhood Hits	856	Shared Neighborhood Hits	52
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

SMC3_HUMAN
NC score	0.066442 (rank : 393)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	246	Target Neighborhood Hits	1186	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

CROCC_HUMAN
NC score	0.066346 (rank : 394)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	246	Target Neighborhood Hits	1409	Shared Neighborhood Hits	65
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

HOOK1_MOUSE
NC score	0.066319 (rank : 395)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	246	Target Neighborhood Hits	910	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

VCAM1_MOUSE
NC score	0.066190 (rank : 396)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	246	Target Neighborhood Hits	320	Shared Neighborhood Hits	32
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

GCC2_HUMAN
NC score	0.066004 (rank : 397)	θ value	0.21417 (rank : 125)
Query Neighborhood Hits	246	Target Neighborhood Hits	1558	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

HOOK2_HUMAN
NC score	0.065960 (rank : 398)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	246	Target Neighborhood Hits	714	Shared Neighborhood Hits	46
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

CAR10_HUMAN
NC score	0.065872 (rank : 399)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	246	Target Neighborhood Hits	569	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CI094_HUMAN
NC score	0.065561 (rank : 400)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

MACOI_MOUSE
NC score	0.065518 (rank : 401)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	246	Target Neighborhood Hits	620	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

SORL_HUMAN
NC score	0.065517 (rank : 402)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	246	Target Neighborhood Hits	440	Shared Neighborhood Hits	50
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

RBP24_HUMAN
NC score	0.065502 (rank : 403)	θ value	0.21417 (rank : 126)
Query Neighborhood Hits	246	Target Neighborhood Hits	1559	Shared Neighborhood Hits	72
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

EP15R_MOUSE
NC score	0.065421 (rank : 404)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	246	Target Neighborhood Hits	1135	Shared Neighborhood Hits	53
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

ECT2_MOUSE
NC score	0.065025 (rank : 405)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	246	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

LRC45_HUMAN
NC score	0.065009 (rank : 406)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	246	Target Neighborhood Hits	933	Shared Neighborhood Hits	47
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

TMF1_HUMAN
NC score	0.064999 (rank : 407)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	246	Target Neighborhood Hits	987	Shared Neighborhood Hits	52
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

SLAP2_MOUSE
NC score	0.064790 (rank : 408)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	246	Target Neighborhood Hits	136	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

GOGA2_MOUSE
NC score	0.064723 (rank : 409)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	246	Target Neighborhood Hits	944	Shared Neighborhood Hits	55
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

JAM1_HUMAN
NC score	0.064567 (rank : 410)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	246	Target Neighborhood Hits	294	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

MACOI_HUMAN
NC score	0.064558 (rank : 411)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	246	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

JAM1_MOUSE
NC score	0.064431 (rank : 412)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	246	Target Neighborhood Hits	287	Shared Neighborhood Hits	32
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

MUC18_MOUSE
NC score	0.064266 (rank : 413)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

DUET_HUMAN
NC score	0.064236 (rank : 414)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	246	Target Neighborhood Hits	1220	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

PCNT_MOUSE
NC score	0.064178 (rank : 415)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	246	Target Neighborhood Hits	1207	Shared Neighborhood Hits	60
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

VCAM1_HUMAN
NC score	0.064171 (rank : 416)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	246	Target Neighborhood Hits	352	Shared Neighborhood Hits	33
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

SLAP2_HUMAN
NC score	0.064041 (rank : 417)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	246	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

ICAM5_HUMAN
NC score	0.064023 (rank : 418)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	246	Target Neighborhood Hits	276	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

CROCC_MOUSE
NC score	0.063993 (rank : 419)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	246	Target Neighborhood Hits	1460	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

NTRI_MOUSE
NC score	0.063969 (rank : 420)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	246	Target Neighborhood Hits	342	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

CD45_HUMAN
NC score	0.063767 (rank : 421)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	246	Target Neighborhood Hits	243	Shared Neighborhood Hits	39
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

SRC_MOUSE
NC score	0.063681 (rank : 422)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	246	Target Neighborhood Hits	1033	Shared Neighborhood Hits	105
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

EP15_MOUSE
NC score	0.063541 (rank : 423)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	246	Target Neighborhood Hits	820	Shared Neighborhood Hits	54
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

KIRR1_HUMAN
NC score	0.063486 (rank : 424)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	246	Target Neighborhood Hits	401	Shared Neighborhood Hits	31
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

CSK_MOUSE
NC score	0.063445 (rank : 425)	θ value	0.0563607 (rank : 102)
Query Neighborhood Hits	246	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

HOOK2_MOUSE
NC score	0.063432 (rank : 426)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	246	Target Neighborhood Hits	736	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

CSK_HUMAN
NC score	0.063393 (rank : 427)	θ value	0.0563607 (rank : 101)
Query Neighborhood Hits	246	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

KIRR3_HUMAN
NC score	0.063344 (rank : 428)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	246	Target Neighborhood Hits	302	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

EP15R_HUMAN
NC score	0.063339 (rank : 429)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	246	Target Neighborhood Hits	1083	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

CNTRB_MOUSE
NC score	0.063322 (rank : 430)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	246	Target Neighborhood Hits	1029	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

F107B_HUMAN
NC score	0.063195 (rank : 431)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	246	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

PGBM_HUMAN
NC score	0.063073 (rank : 432)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	246	Target Neighborhood Hits	1113	Shared Neighborhood Hits	45
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CKAP4_HUMAN
NC score	0.063051 (rank : 433)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	246	Target Neighborhood Hits	592	Shared Neighborhood Hits	43
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CEP63_HUMAN
NC score	0.062964 (rank : 434)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	246	Target Neighborhood Hits	1005	Shared Neighborhood Hits	55
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

NUMA1_HUMAN
NC score	0.062943 (rank : 435)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	246	Target Neighborhood Hits	1523	Shared Neighborhood Hits	75
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

RFIP3_HUMAN
NC score	0.062810 (rank : 436)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	246	Target Neighborhood Hits	1055	Shared Neighborhood Hits	50
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

BAIP2_MOUSE
NC score	0.062809 (rank : 437)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	246	Target Neighborhood Hits	185	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

NTRI_HUMAN
NC score	0.062767 (rank : 438)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	246	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NIN_HUMAN
NC score	0.062760 (rank : 439)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	246	Target Neighborhood Hits	1416	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CE152_HUMAN
NC score	0.062752 (rank : 440)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	246	Target Neighborhood Hits	976	Shared Neighborhood Hits	55
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

IF3A_MOUSE
NC score	0.062557 (rank : 441)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	246	Target Neighborhood Hits	871	Shared Neighborhood Hits	50
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

EP15_HUMAN
NC score	0.062554 (rank : 442)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	246	Target Neighborhood Hits	1021	Shared Neighborhood Hits	53
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

KIRR3_MOUSE
NC score	0.062495 (rank : 443)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

GOGA1_MOUSE
NC score	0.062366 (rank : 444)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	246	Target Neighborhood Hits	994	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MCF2_HUMAN
NC score	0.062319 (rank : 445)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	246	Target Neighborhood Hits	166	Shared Neighborhood Hits	24
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

CNTRB_HUMAN
NC score	0.062281 (rank : 446)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	246	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CSKP_HUMAN
NC score	0.062208 (rank : 447)	θ value	0.163984 (rank : 117)
Query Neighborhood Hits	246	Target Neighborhood Hits	1022	Shared Neighborhood Hits	87
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

KIRR1_MOUSE
NC score	0.062194 (rank : 448)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	246	Target Neighborhood Hits	403	Shared Neighborhood Hits	31
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

ECT2_HUMAN
NC score	0.062174 (rank : 449)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	246	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

GCC2_MOUSE
NC score	0.062146 (rank : 450)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	246	Target Neighborhood Hits	1619	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CI093_HUMAN
NC score	0.062134 (rank : 451)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	246	Target Neighborhood Hits	1088	Shared Neighborhood Hits	52
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

LU_HUMAN
NC score	0.062031 (rank : 452)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	246	Target Neighborhood Hits	283	Shared Neighborhood Hits	33
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

CYLN2_MOUSE
NC score	0.062024 (rank : 453)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	246	Target Neighborhood Hits	1002	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

F107B_MOUSE
NC score	0.061984 (rank : 454)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	246	Target Neighborhood Hits	126	Shared Neighborhood Hits	16
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

BI2L1_MOUSE
NC score	0.061963 (rank : 455)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	246	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

HOOK3_MOUSE
NC score	0.061933 (rank : 456)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	246	Target Neighborhood Hits	1007	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

PGBM_MOUSE
NC score	0.061899 (rank : 457)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	246	Target Neighborhood Hits	1073	Shared Neighborhood Hits	45
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ING3_HUMAN
NC score	0.061884 (rank : 458)	θ value	0.0563607 (rank : 104)
Query Neighborhood Hits	246	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

GAS8_HUMAN
NC score	0.061784 (rank : 459)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	246	Target Neighborhood Hits	819	Shared Neighborhood Hits	47
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

RGNEF_MOUSE
NC score	0.061628 (rank : 460)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	246	Target Neighborhood Hits	641	Shared Neighborhood Hits	39
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

INVO_MOUSE
NC score	0.061577 (rank : 461)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	246	Target Neighborhood Hits	474	Shared Neighborhood Hits	37
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

HOOK3_HUMAN
NC score	0.061573 (rank : 462)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	246	Target Neighborhood Hits	1070	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

EVPL_HUMAN
NC score	0.061493 (rank : 463)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	246	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

CT116_MOUSE
NC score	0.061491 (rank : 464)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	246	Target Neighborhood Hits	268	Shared Neighborhood Hits	25
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

SYCP1_HUMAN
NC score	0.061379 (rank : 465)	θ value	0.21417 (rank : 128)
Query Neighborhood Hits	246	Target Neighborhood Hits	1313	Shared Neighborhood Hits	59
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SN_MOUSE
NC score	0.061285 (rank : 466)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	246	Target Neighborhood Hits	416	Shared Neighborhood Hits	34
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

PEPL_MOUSE
NC score	0.061262 (rank : 467)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	246	Target Neighborhood Hits	1105	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

NEMO_HUMAN
NC score	0.061053 (rank : 468)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	246	Target Neighborhood Hits	820	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

CARD9_HUMAN
NC score	0.061033 (rank : 469)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	246	Target Neighborhood Hits	602	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

GOGA6_HUMAN
NC score	0.061001 (rank : 470)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	246	Target Neighborhood Hits	1007	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

TUFT1_MOUSE
NC score	0.060950 (rank : 471)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	246	Target Neighborhood Hits	732	Shared Neighborhood Hits	49
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

JAM2_HUMAN
NC score	0.060948 (rank : 472)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	246	Target Neighborhood Hits	304	Shared Neighborhood Hits	33
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

MD1L1_HUMAN
NC score	0.060929 (rank : 473)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	246	Target Neighborhood Hits	893	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CCD41_MOUSE
NC score	0.060907 (rank : 474)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	246	Target Neighborhood Hits	1399	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

ERC2_HUMAN
NC score	0.060881 (rank : 475)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	246	Target Neighborhood Hits	1156	Shared Neighborhood Hits	62
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CD22_MOUSE
NC score	0.060804 (rank : 476)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	246	Target Neighborhood Hits	331	Shared Neighborhood Hits	29
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

PTK7_HUMAN
NC score	0.060747 (rank : 477)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	246	Target Neighborhood Hits	1103	Shared Neighborhood Hits	54
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

LRRF2_HUMAN
NC score	0.060616 (rank : 478)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	246	Target Neighborhood Hits	791	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

RPGR1_MOUSE
NC score	0.060515 (rank : 479)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	246	Target Neighborhood Hits	713	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

HCK_MOUSE
NC score	0.060514 (rank : 480)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	246	Target Neighborhood Hits	1029	Shared Neighborhood Hits	105
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

CCD42_HUMAN
NC score	0.060354 (rank : 481)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	246	Target Neighborhood Hits	406	Shared Neighborhood Hits	34
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

I12R1_HUMAN
NC score	0.060348 (rank : 482)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	246	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

SORL_MOUSE
NC score	0.060345 (rank : 483)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	246	Target Neighborhood Hits	439	Shared Neighborhood Hits	47
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

BAIP2_HUMAN
NC score	0.060295 (rank : 484)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	246	Target Neighborhood Hits	192	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

IF3A_HUMAN
NC score	0.060198 (rank : 485)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	246	Target Neighborhood Hits	875	Shared Neighborhood Hits	51
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

BASI_HUMAN
NC score	0.060163 (rank : 486)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	246	Target Neighborhood Hits	211	Shared Neighborhood Hits	32
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

GCC1_HUMAN
NC score	0.060114 (rank : 487)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	246	Target Neighborhood Hits	887	Shared Neighborhood Hits	47
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

NIN_MOUSE
NC score	0.060082 (rank : 488)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	246	Target Neighborhood Hits	1376	Shared Neighborhood Hits	62
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

RILP_HUMAN
NC score	0.060079 (rank : 489)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	246	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

SYCP1_MOUSE
NC score	0.059976 (rank : 490)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	246	Target Neighborhood Hits	1456	Shared Neighborhood Hits	62
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

HCK_HUMAN
NC score	0.059970 (rank : 491)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	246	Target Neighborhood Hits	1035	Shared Neighborhood Hits	105
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

GCC1_MOUSE
NC score	0.059956 (rank : 492)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	246	Target Neighborhood Hits	777	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

AMOL2_HUMAN
NC score	0.059838 (rank : 493)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	246	Target Neighborhood Hits	603	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

ENAH_HUMAN
NC score	0.059833 (rank : 494)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	246	Target Neighborhood Hits	784	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ERC2_MOUSE
NC score	0.059795 (rank : 495)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	246	Target Neighborhood Hits	1166	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

HMCN1_HUMAN
NC score	0.059657 (rank : 496)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	246	Target Neighborhood Hits	983	Shared Neighborhood Hits	39
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ARHGC_HUMAN
NC score	0.059602 (rank : 497)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	246	Target Neighborhood Hits	351	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

GOGA3_HUMAN
NC score	0.059576 (rank : 498)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	246	Target Neighborhood Hits	1317	Shared Neighborhood Hits	65
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

FLIP1_HUMAN
NC score	0.059493 (rank : 499)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	246	Target Neighborhood Hits	1405	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

OBSCN_HUMAN
NC score	0.059470 (rank : 500)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	246	Target Neighborhood Hits	1931	Shared Neighborhood Hits	89
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TRIPB_HUMAN
NC score	0.059465 (rank : 501)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	246	Target Neighborhood Hits	1587	Shared Neighborhood Hits	73
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

MARCS_MOUSE
NC score	0.059462 (rank : 502)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

FCRL2_HUMAN
NC score	0.059265 (rank : 503)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	246	Target Neighborhood Hits	251	Shared Neighborhood Hits	29
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

HOOK1_HUMAN
NC score	0.059236 (rank : 504)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	246	Target Neighborhood Hits	942	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

ARHGC_MOUSE
NC score	0.059214 (rank : 505)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	246	Target Neighborhood Hits	344	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

P55G_HUMAN
NC score	0.059196 (rank : 506)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	246	Target Neighborhood Hits	451	Shared Neighborhood Hits	56
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

KTN1_MOUSE
NC score	0.059109 (rank : 507)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	246	Target Neighborhood Hits	1324	Shared Neighborhood Hits	59
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYH11_HUMAN
NC score	0.059053 (rank : 508)	θ value	0.125558 (rank : 116)
Query Neighborhood Hits	246	Target Neighborhood Hits	1806	Shared Neighborhood Hits	81
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

REST_MOUSE
NC score	0.058938 (rank : 509)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	246	Target Neighborhood Hits	1506	Shared Neighborhood Hits	64
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

MYH9_MOUSE
NC score	0.058936 (rank : 510)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	246	Target Neighborhood Hits	1829	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

DLG2_HUMAN
NC score	0.058924 (rank : 511)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	246	Target Neighborhood Hits	279	Shared Neighborhood Hits	59
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LZTS1_HUMAN
NC score	0.058913 (rank : 512)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	246	Target Neighborhood Hits	532	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

BASI_MOUSE
NC score	0.058787 (rank : 513)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	246	Target Neighborhood Hits	238	Shared Neighborhood Hits	31
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

OPTN_MOUSE
NC score	0.058696 (rank : 514)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	246	Target Neighborhood Hits	1120	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

LYN_MOUSE
NC score	0.058640 (rank : 515)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	246	Target Neighborhood Hits	1023	Shared Neighborhood Hits	100
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

SN_HUMAN
NC score	0.058613 (rank : 516)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	246	Target Neighborhood Hits	434	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

ARHG1_HUMAN
NC score	0.058609 (rank : 517)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	246	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

DLG5_HUMAN
NC score	0.058411 (rank : 518)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	246	Target Neighborhood Hits	1088	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

NDE1_HUMAN
NC score	0.058300 (rank : 519)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	246	Target Neighborhood Hits	823	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

MYH11_MOUSE
NC score	0.058168 (rank : 520)	θ value	0.0961366 (rank : 115)
Query Neighborhood Hits	246	Target Neighborhood Hits	1777	Shared Neighborhood Hits	77
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GOGB1_HUMAN
NC score	0.058165 (rank : 521)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	246	Target Neighborhood Hits	2297	Shared Neighborhood Hits	80
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CYLN2_HUMAN
NC score	0.058140 (rank : 522)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	246	Target Neighborhood Hits	1004	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

GRAP1_HUMAN
NC score	0.058063 (rank : 523)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	246	Target Neighborhood Hits	944	Shared Neighborhood Hits	58
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

U2AFM_MOUSE
NC score	0.057879 (rank : 524)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	246	Target Neighborhood Hits	543	Shared Neighborhood Hits	41
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

EVPL_MOUSE
NC score	0.057833 (rank : 525)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	246	Target Neighborhood Hits	952	Shared Neighborhood Hits	56
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

CCD46_HUMAN
NC score	0.057792 (rank : 526)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	246	Target Neighborhood Hits	1430	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

DESP_HUMAN
NC score	0.057574 (rank : 527)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	246	Target Neighborhood Hits	1470	Shared Neighborhood Hits	67
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CING_HUMAN
NC score	0.057534 (rank : 528)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	246	Target Neighborhood Hits	1275	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

GOGA3_MOUSE
NC score	0.057496 (rank : 529)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	246	Target Neighborhood Hits	1437	Shared Neighborhood Hits	65
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CT116_HUMAN
NC score	0.057460 (rank : 530)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	246	Target Neighborhood Hits	294	Shared Neighborhood Hits	25
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

SLAP1_HUMAN
NC score	0.057435 (rank : 531)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	246	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

RBM25_HUMAN
NC score	0.057435 (rank : 532)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	246	Target Neighborhood Hits	682	Shared Neighborhood Hits	40
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

NAF1_MOUSE
NC score	0.057384 (rank : 533)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	246	Target Neighborhood Hits	852	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

CSKP_MOUSE
NC score	0.057344 (rank : 534)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	246	Target Neighborhood Hits	1027	Shared Neighborhood Hits	91
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CCD11_HUMAN
NC score	0.057301 (rank : 535)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	246	Target Neighborhood Hits	822	Shared Neighborhood Hits	48
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

MYH9_HUMAN
NC score	0.057249 (rank : 536)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	246	Target Neighborhood Hits	1762	Shared Neighborhood Hits	75
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

KGUA_MOUSE
NC score	0.057241 (rank : 537)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	246	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

CING_MOUSE
NC score	0.057239 (rank : 538)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	246	Target Neighborhood Hits	1432	Shared Neighborhood Hits	65
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

TEX9_MOUSE
NC score	0.057230 (rank : 539)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	246	Target Neighborhood Hits	581	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

MUSK_MOUSE
NC score	0.057229 (rank : 540)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	246	Target Neighborhood Hits	1057	Shared Neighborhood Hits	53
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

LRIG2_HUMAN
NC score	0.057180 (rank : 541)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	246	Target Neighborhood Hits	595	Shared Neighborhood Hits	35
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

TAXB1_HUMAN
NC score	0.057175 (rank : 542)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	246	Target Neighborhood Hits	829	Shared Neighborhood Hits	49
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

LRIG1_MOUSE
NC score	0.057100 (rank : 543)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	246	Target Neighborhood Hits	627	Shared Neighborhood Hits	36
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_MOUSE
NC score	0.057070 (rank : 544)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	246	Target Neighborhood Hits	586	Shared Neighborhood Hits	35
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG1_HUMAN
NC score	0.057045 (rank : 545)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	246	Target Neighborhood Hits	654	Shared Neighborhood Hits	35
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

BICD2_HUMAN
NC score	0.057014 (rank : 546)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	246	Target Neighborhood Hits	856	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

PEPL_HUMAN
NC score	0.057002 (rank : 547)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	246	Target Neighborhood Hits	1141	Shared Neighborhood Hits	51
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

KGUA_HUMAN
NC score	0.056987 (rank : 548)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	246	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

MUSK_HUMAN
NC score	0.056936 (rank : 549)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	246	Target Neighborhood Hits	1074	Shared Neighborhood Hits	53
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

LYN_HUMAN
NC score	0.056936 (rank : 550)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	246	Target Neighborhood Hits	1022	Shared Neighborhood Hits	99
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

NEMO_MOUSE
NC score	0.056929 (rank : 551)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	246	Target Neighborhood Hits	658	Shared Neighborhood Hits	45
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

RRBP1_HUMAN
NC score	0.056927 (rank : 552)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	246	Target Neighborhood Hits	1306	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

ARHGB_HUMAN
NC score	0.056892 (rank : 553)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	246	Target Neighborhood Hits	375	Shared Neighborhood Hits	28
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

CAR10_MOUSE
NC score	0.056838 (rank : 554)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	246	Target Neighborhood Hits	407	Shared Neighborhood Hits	36
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

P55G_MOUSE
NC score	0.056819 (rank : 555)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	246	Target Neighborhood Hits	401	Shared Neighborhood Hits	52
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

HCFC2_MOUSE
NC score	0.056809 (rank : 556)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	246	Target Neighborhood Hits	97	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

MD1L1_MOUSE
NC score	0.056700 (rank : 557)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	246	Target Neighborhood Hits	1001	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

GCP60_MOUSE
NC score	0.056604 (rank : 558)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	246	Target Neighborhood Hits	395	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

MFA3L_HUMAN
NC score	0.056578 (rank : 559)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	246	Target Neighborhood Hits	230	Shared Neighborhood Hits	32
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

VSIG2_HUMAN
NC score	0.056507 (rank : 560)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	246	Target Neighborhood Hits	321	Shared Neighborhood Hits	32
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

MY18A_MOUSE
NC score	0.056500 (rank : 561)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	246	Target Neighborhood Hits	1989	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

LRIG3_MOUSE
NC score	0.056496 (rank : 562)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	246	Target Neighborhood Hits	611	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

CCHCR_MOUSE
NC score	0.056479 (rank : 563)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	246	Target Neighborhood Hits	932	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

TRAIP_HUMAN
NC score	0.056473 (rank : 564)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	246	Target Neighborhood Hits	780	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

HMMR_HUMAN
NC score	0.056440 (rank : 565)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	246	Target Neighborhood Hits	1082	Shared Neighborhood Hits	58
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

RRBP1_MOUSE
NC score	0.056439 (rank : 566)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	246	Target Neighborhood Hits	1650	Shared Neighborhood Hits	64
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

GRAP1_MOUSE
NC score	0.056402 (rank : 567)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	246	Target Neighborhood Hits	1234	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

CCD42_MOUSE
NC score	0.056385 (rank : 568)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	246	Target Neighborhood Hits	284	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

RB6I2_MOUSE
NC score	0.056372 (rank : 569)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	246	Target Neighborhood Hits	1433	Shared Neighborhood Hits	61
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

DLG2_MOUSE
NC score	0.056340 (rank : 570)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	57
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LRIG3_HUMAN
NC score	0.056333 (rank : 571)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	246	Target Neighborhood Hits	601	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

GOGA5_MOUSE
NC score	0.056306 (rank : 572)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	246	Target Neighborhood Hits	1434	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

KTN1_HUMAN
NC score	0.056302 (rank : 573)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	246	Target Neighborhood Hits	1197	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

JAM2_MOUSE
NC score	0.056261 (rank : 574)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

GOGA4_MOUSE
NC score	0.056206 (rank : 575)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	246	Target Neighborhood Hits	1939	Shared Neighborhood Hits	72
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

RASA1_HUMAN
NC score	0.056151 (rank : 576)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	246	Target Neighborhood Hits	258	Shared Neighborhood Hits	35
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

CSF3R_MOUSE
NC score	0.056127 (rank : 577)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	246	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CU013_HUMAN
NC score	0.056123 (rank : 578)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	246	Target Neighborhood Hits	405	Shared Neighborhood Hits	36
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CALD1_HUMAN
NC score	0.056086 (rank : 579)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	246	Target Neighborhood Hits	959	Shared Neighborhood Hits	51
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

PHLB3_HUMAN
NC score	0.056068 (rank : 580)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	246	Target Neighborhood Hits	304	Shared Neighborhood Hits	30
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

AKAP9_HUMAN
NC score	0.055983 (rank : 581)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	246	Target Neighborhood Hits	1710	Shared Neighborhood Hits	63
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

FRK_HUMAN
NC score	0.055966 (rank : 582)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	246	Target Neighborhood Hits	1058	Shared Neighborhood Hits	112
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

T3JAM_MOUSE
NC score	0.055953 (rank : 583)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	246	Target Neighborhood Hits	535	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

MY18A_HUMAN
NC score	0.055939 (rank : 584)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	246	Target Neighborhood Hits	1929	Shared Neighborhood Hits	87
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NAF1_HUMAN
NC score	0.055915 (rank : 585)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	246	Target Neighborhood Hits	937	Shared Neighborhood Hits	43
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

TUFT1_HUMAN
NC score	0.055887 (rank : 586)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	246	Target Neighborhood Hits	686	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

SDCG8_HUMAN
NC score	0.055882 (rank : 587)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	246	Target Neighborhood Hits	1002	Shared Neighborhood Hits	49
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

IFT81_MOUSE
NC score	0.055879 (rank : 588)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	246	Target Neighborhood Hits	959	Shared Neighborhood Hits	45
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

CYTSA_HUMAN
NC score	0.055788 (rank : 589)	θ value	0.47712 (rank : 140)
Query Neighborhood Hits	246	Target Neighborhood Hits	1138	Shared Neighborhood Hits	63
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

BRE1B_HUMAN
NC score	0.055750 (rank : 590)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	246	Target Neighborhood Hits	1040	Shared Neighborhood Hits	43
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

NEB1_HUMAN
NC score	0.055654 (rank : 591)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	246	Target Neighborhood Hits	829	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

CCD46_MOUSE
NC score	0.055558 (rank : 592)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	246	Target Neighborhood Hits	1405	Shared Neighborhood Hits	66
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CK5P2_HUMAN
NC score	0.055522 (rank : 593)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	246	Target Neighborhood Hits	1433	Shared Neighborhood Hits	71
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

SLAP1_MOUSE
NC score	0.055386 (rank : 594)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	246	Target Neighborhood Hits	117	Shared Neighborhood Hits	22
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

ARHG1_MOUSE
NC score	0.055367 (rank : 595)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

RUFY2_HUMAN
NC score	0.055339 (rank : 596)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	246	Target Neighborhood Hits	1208	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CD45_MOUSE
NC score	0.055269 (rank : 597)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	246	Target Neighborhood Hits	178	Shared Neighborhood Hits	26
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

LZTS1_MOUSE
NC score	0.055266 (rank : 598)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	246	Target Neighborhood Hits	540	Shared Neighborhood Hits	39
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

CCD41_HUMAN
NC score	0.055246 (rank : 599)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	246	Target Neighborhood Hits	1139	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

TPR_HUMAN
NC score	0.055238 (rank : 600)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	246	Target Neighborhood Hits	1921	Shared Neighborhood Hits	74
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

RAD50_MOUSE
NC score	0.055226 (rank : 601)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	246	Target Neighborhood Hits	1366	Shared Neighborhood Hits	61
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CD22_HUMAN
NC score	0.055109 (rank : 602)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	246	Target Neighborhood Hits	365	Shared Neighborhood Hits	31
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

EEA1_HUMAN
NC score	0.055094 (rank : 603)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	246	Target Neighborhood Hits	1796	Shared Neighborhood Hits	69
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

BICD2_MOUSE
NC score	0.055086 (rank : 604)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	246	Target Neighborhood Hits	864	Shared Neighborhood Hits	51
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

SAKS1_MOUSE
NC score	0.055060 (rank : 605)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	246	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

CAR11_HUMAN
NC score	0.055058 (rank : 606)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	246	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

GAS8_MOUSE
NC score	0.055046 (rank : 607)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	246	Target Neighborhood Hits	622	Shared Neighborhood Hits	44
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

FCRL5_HUMAN
NC score	0.055042 (rank : 608)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	246	Target Neighborhood Hits	267	Shared Neighborhood Hits	29
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

RPGR1_HUMAN
NC score	0.055029 (rank : 609)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	246	Target Neighborhood Hits	578	Shared Neighborhood Hits	37
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

LNK_HUMAN
NC score	0.054976 (rank : 610)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	246	Target Neighborhood Hits	151	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

HAPIP_HUMAN
NC score	0.054893 (rank : 611)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	246	Target Neighborhood Hits	350	Shared Neighborhood Hits	40
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

SWP70_HUMAN
NC score	0.054823 (rank : 612)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	246	Target Neighborhood Hits	973	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

FLIP1_MOUSE
NC score	0.054812 (rank : 613)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	246	Target Neighborhood Hits	1176	Shared Neighborhood Hits	64
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

TYRO3_HUMAN
NC score	0.054806 (rank : 614)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	246	Target Neighborhood Hits	995	Shared Neighborhood Hits	61
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TRIO_HUMAN
NC score	0.054781 (rank : 615)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	246	Target Neighborhood Hits	1580	Shared Neighborhood Hits	115
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

GOGA4_HUMAN
NC score	0.054721 (rank : 616)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	246	Target Neighborhood Hits	2034	Shared Neighborhood Hits	83
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CASP_HUMAN
NC score	0.054656 (rank : 617)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	246	Target Neighborhood Hits	1131	Shared Neighborhood Hits	55
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

PLVAP_HUMAN
NC score	0.054438 (rank : 618)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	246	Target Neighborhood Hits	397	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

EEA1_MOUSE
NC score	0.054378 (rank : 619)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	246	Target Neighborhood Hits	1637	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

OPTN_HUMAN
NC score	0.054316 (rank : 620)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	246	Target Neighborhood Hits	827	Shared Neighborhood Hits	45
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

ARHG2_HUMAN
NC score	0.054302 (rank : 621)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	246	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

HMMR_MOUSE
NC score	0.054302 (rank : 622)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	246	Target Neighborhood Hits	1178	Shared Neighborhood Hits	62
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CCD19_HUMAN
NC score	0.054285 (rank : 623)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	246	Target Neighborhood Hits	639	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CYTSA_MOUSE
NC score	0.054220 (rank : 624)	θ value	1.38821 (rank : 164)
Query Neighborhood Hits	246	Target Neighborhood Hits	1104	Shared Neighborhood Hits	62
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

CENPF_HUMAN
NC score	0.054197 (rank : 625)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	246	Target Neighborhood Hits	1932	Shared Neighborhood Hits	77
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CCD11_MOUSE
NC score	0.054140 (rank : 626)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	246	Target Neighborhood Hits	498	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

GCP60_HUMAN
NC score	0.053948 (rank : 627)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	246	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

PTPRA_HUMAN
NC score	0.053853 (rank : 628)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	246	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRE_MOUSE
NC score	0.053849 (rank : 629)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_MOUSE
NC score	0.053838 (rank : 630)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	246	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

BLK_MOUSE
NC score	0.053802 (rank : 631)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	246	Target Neighborhood Hits	992	Shared Neighborhood Hits	82
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

PTPRE_HUMAN
NC score	0.053725 (rank : 632)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	246	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

DLG3_HUMAN
NC score	0.053665 (rank : 633)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	246	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

ADIP_HUMAN
NC score	0.053615 (rank : 634)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	246	Target Neighborhood Hits	470	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

CT2NL_HUMAN
NC score	0.053595 (rank : 635)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	246	Target Neighborhood Hits	1059	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FYCO1_HUMAN
NC score	0.053535 (rank : 636)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	246	Target Neighborhood Hits	1149	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

CAF1A_HUMAN
NC score	0.053527 (rank : 637)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	246	Target Neighborhood Hits	750	Shared Neighborhood Hits	47
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

SMC2_HUMAN
NC score	0.053520 (rank : 638)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	246	Target Neighborhood Hits	1405	Shared Neighborhood Hits	62
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CF060_HUMAN
NC score	0.053467 (rank : 639)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	246	Target Neighborhood Hits	1270	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CP135_MOUSE
NC score	0.053416 (rank : 640)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	246	Target Neighborhood Hits	1278	Shared Neighborhood Hits	57
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

RUFY1_MOUSE
NC score	0.053410 (rank : 641)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	246	Target Neighborhood Hits	765	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

TYRO3_MOUSE
NC score	0.053375 (rank : 642)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	246	Target Neighborhood Hits	1007	Shared Neighborhood Hits	63
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

PHLB1_HUMAN
NC score	0.053354 (rank : 643)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	246	Target Neighborhood Hits	1038	Shared Neighborhood Hits	48
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CEP55_MOUSE
NC score	0.053314 (rank : 644)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	246	Target Neighborhood Hits	693	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

HAP1_MOUSE
NC score	0.053310 (rank : 645)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	246	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

LMO7_HUMAN
NC score	0.053254 (rank : 646)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	246	Target Neighborhood Hits	507	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

RB6I2_HUMAN
NC score	0.053214 (rank : 647)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	246	Target Neighborhood Hits	1584	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

I12R1_MOUSE
NC score	0.053189 (rank : 648)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	246	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

DLG3_MOUSE
NC score	0.053183 (rank : 649)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	246	Target Neighborhood Hits	274	Shared Neighborhood Hits	55
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

CASP_MOUSE
NC score	0.053140 (rank : 650)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	246	Target Neighborhood Hits	1152	Shared Neighborhood Hits	61
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

MYH10_HUMAN
NC score	0.053111 (rank : 651)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	246	Target Neighborhood Hits	1620	Shared Neighborhood Hits	67
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.053078 (rank : 652)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	246	Target Neighborhood Hits	1612	Shared Neighborhood Hits	67
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

VSIG2_MOUSE
NC score	0.053051 (rank : 653)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	246	Target Neighborhood Hits	316	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

HIP1R_HUMAN
NC score	0.053003 (rank : 654)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	246	Target Neighborhood Hits	809	Shared Neighborhood Hits	50
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

IFT81_HUMAN
NC score	0.052916 (rank : 655)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	246	Target Neighborhood Hits	893	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IGS4B_MOUSE
NC score	0.052916 (rank : 656)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	246	Target Neighborhood Hits	328	Shared Neighborhood Hits	30
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

CDR2_MOUSE
NC score	0.052817 (rank : 657)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	246	Target Neighborhood Hits	482	Shared Neighborhood Hits	37
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

TIE2_HUMAN
NC score	0.052815 (rank : 658)	θ value	1.06291 (rank : 163)
Query Neighborhood Hits	246	Target Neighborhood Hits	1192	Shared Neighborhood Hits	67
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

IFT74_MOUSE
NC score	0.052794 (rank : 659)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	246	Target Neighborhood Hits	939	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

BRE1A_HUMAN
NC score	0.052792 (rank : 660)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	246	Target Neighborhood Hits	1071	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CAF1A_MOUSE
NC score	0.052759 (rank : 661)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	246	Target Neighborhood Hits	736	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

MYH14_HUMAN
NC score	0.052756 (rank : 662)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	246	Target Neighborhood Hits	995	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

SPEG_HUMAN
NC score	0.052722 (rank : 663)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	246	Target Neighborhood Hits	1762	Shared Neighborhood Hits	76
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

GOGA5_HUMAN
NC score	0.052718 (rank : 664)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	246	Target Neighborhood Hits	1168	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

UFO_MOUSE
NC score	0.052708 (rank : 665)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	246	Target Neighborhood Hits	988	Shared Neighborhood Hits	69
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

MYH14_MOUSE
NC score	0.052683 (rank : 666)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	246	Target Neighborhood Hits	1225	Shared Neighborhood Hits	57
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

BLK_HUMAN
NC score	0.052588 (rank : 667)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	246	Target Neighborhood Hits	994	Shared Neighborhood Hits	87
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

LIPA2_MOUSE
NC score	0.052576 (rank : 668)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	246	Target Neighborhood Hits	1282	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

CKAP4_MOUSE
NC score	0.052453 (rank : 669)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	246	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

RAD50_HUMAN
NC score	0.052452 (rank : 670)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	246	Target Neighborhood Hits	1317	Shared Neighborhood Hits	60
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TPM4_MOUSE
NC score	0.052428 (rank : 671)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	246	Target Neighborhood Hits	703	Shared Neighborhood Hits	47
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

IGS4B_HUMAN
NC score	0.052335 (rank : 672)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	246	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

JIP2_HUMAN
NC score	0.052323 (rank : 673)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	44
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

LBC_HUMAN
NC score	0.052282 (rank : 674)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	246	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

HOME1_MOUSE
NC score	0.052043 (rank : 675)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	246	Target Neighborhood Hits	630	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

MERTK_HUMAN
NC score	0.052040 (rank : 676)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	246	Target Neighborhood Hits	988	Shared Neighborhood Hits	59
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

LUZP1_HUMAN
NC score	0.052033 (rank : 677)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	246	Target Neighborhood Hits	739	Shared Neighborhood Hits	46
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

TPM2_HUMAN
NC score	0.051998 (rank : 678)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	246	Target Neighborhood Hits	677	Shared Neighborhood Hits	49
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TXK_MOUSE
NC score	0.051998 (rank : 679)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	246	Target Neighborhood Hits	980	Shared Neighborhood Hits	91
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

CEAM5_HUMAN
NC score	0.051916 (rank : 680)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	246	Target Neighborhood Hits	343	Shared Neighborhood Hits	34
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

JIP1_HUMAN
NC score	0.051889 (rank : 681)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

HIP1R_MOUSE
NC score	0.051785 (rank : 682)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	246	Target Neighborhood Hits	959	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

FYCO1_MOUSE
NC score	0.051776 (rank : 683)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	246	Target Neighborhood Hits	1059	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

ANGL2_HUMAN
NC score	0.051762 (rank : 684)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	246	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

RABE1_HUMAN
NC score	0.051703 (rank : 685)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	246	Target Neighborhood Hits	1104	Shared Neighborhood Hits	55
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

PHLB1_MOUSE
NC score	0.051665 (rank : 686)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	246	Target Neighborhood Hits	678	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

BPAEA_MOUSE
NC score	0.051662 (rank : 687)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	246	Target Neighborhood Hits	1480	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RABE2_MOUSE
NC score	0.051604 (rank : 688)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	246	Target Neighborhood Hits	598	Shared Neighborhood Hits	45
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

TIE2_MOUSE
NC score	0.051536 (rank : 689)	θ value	1.81305 (rank : 179)
Query Neighborhood Hits	246	Target Neighborhood Hits	1204	Shared Neighborhood Hits	67
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

ANGP2_HUMAN
NC score	0.051499 (rank : 690)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	246	Target Neighborhood Hits	400	Shared Neighborhood Hits	33
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

DLG1_HUMAN
NC score	0.051439 (rank : 691)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	246	Target Neighborhood Hits	290	Shared Neighborhood Hits	55
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

PLEC1_HUMAN
NC score	0.051422 (rank : 692)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	246	Target Neighborhood Hits	1326	Shared Neighborhood Hits	63
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MFA3L_MOUSE
NC score	0.051402 (rank : 693)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	246	Target Neighborhood Hits	214	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

PTPRZ_HUMAN
NC score	0.051393 (rank : 694)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	246	Target Neighborhood Hits	255	Shared Neighborhood Hits	23
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PIBF1_HUMAN
NC score	0.051229 (rank : 695)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	246	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

CI039_HUMAN
NC score	0.051206 (rank : 696)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	246	Target Neighborhood Hits	1171	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

TXLNA_HUMAN
NC score	0.051198 (rank : 697)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	246	Target Neighborhood Hits	982	Shared Neighborhood Hits	50
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

IF31_HUMAN
NC score	0.051192 (rank : 698)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	246	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

CCDC6_HUMAN
NC score	0.051110 (rank : 699)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	246	Target Neighborhood Hits	723	Shared Neighborhood Hits	42
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

DAPP1_MOUSE
NC score	0.051103 (rank : 700)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PTPRG_MOUSE
NC score	0.051085 (rank : 701)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	246	Target Neighborhood Hits	260	Shared Neighborhood Hits	24
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

UFO_HUMAN
NC score	0.051053 (rank : 702)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	246	Target Neighborhood Hits	981	Shared Neighborhood Hits	63
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

BRE1B_MOUSE
NC score	0.051043 (rank : 703)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	246	Target Neighborhood Hits	970	Shared Neighborhood Hits	42
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CP135_HUMAN
NC score	0.051013 (rank : 704)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	246	Target Neighborhood Hits	1290	Shared Neighborhood Hits	59
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

YETS2_HUMAN
NC score	0.050998 (rank : 705)	θ value	0.163984 (rank : 122)
Query Neighborhood Hits	246	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

DAPP1_HUMAN
NC score	0.050993 (rank : 706)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

SHC3_MOUSE
NC score	0.050950 (rank : 707)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	246	Target Neighborhood Hits	151	Shared Neighborhood Hits	29
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

TPM2_MOUSE
NC score	0.050944 (rank : 708)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	246	Target Neighborhood Hits	676	Shared Neighborhood Hits	49
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

IF31_MOUSE
NC score	0.050936 (rank : 709)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	246	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q66JS6, Q8BUW6	Gene names	Eif3s1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha).

GNRP_MOUSE
NC score	0.050806 (rank : 710)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	246	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

CEAM1_MOUSE
NC score	0.050800 (rank : 711)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	246	Target Neighborhood Hits	326	Shared Neighborhood Hits	33
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

IL27B_HUMAN
NC score	0.050779 (rank : 712)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	246	Target Neighborhood Hits	80	Shared Neighborhood Hits	31
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

ABL1_HUMAN
NC score	0.050767 (rank : 713)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	246	Target Neighborhood Hits	1220	Shared Neighborhood Hits	90
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

DLG1_MOUSE
NC score	0.050759 (rank : 714)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	246	Target Neighborhood Hits	285	Shared Neighborhood Hits	58
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

ANGL2_MOUSE
NC score	0.050740 (rank : 715)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

RFIP4_HUMAN
NC score	0.050590 (rank : 716)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	246	Target Neighborhood Hits	785	Shared Neighborhood Hits	50
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

MY18B_HUMAN
NC score	0.050531 (rank : 717)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	246	Target Neighborhood Hits	1299	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CK5P2_MOUSE
NC score	0.050500 (rank : 718)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	246	Target Neighborhood Hits	1151	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

ABL1_MOUSE
NC score	0.050443 (rank : 719)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	246	Target Neighborhood Hits	1178	Shared Neighborhood Hits	92
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SH21B_HUMAN
NC score	0.050437 (rank : 720)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	246	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

ENAH_MOUSE
NC score	0.050429 (rank : 721)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	246	Target Neighborhood Hits	919	Shared Neighborhood Hits	52
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CENPE_HUMAN
NC score	0.050418 (rank : 722)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	246	Target Neighborhood Hits	2060	Shared Neighborhood Hits	72
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

NRG2_MOUSE
NC score	0.050413 (rank : 723)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	246	Target Neighborhood Hits	392	Shared Neighborhood Hits	33
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

TPM3_HUMAN
NC score	0.050380 (rank : 724)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	246	Target Neighborhood Hits	689	Shared Neighborhood Hits	52
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

PTPRG_HUMAN
NC score	0.050323 (rank : 725)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	246	Target Neighborhood Hits	231	Shared Neighborhood Hits	24
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RBCC1_HUMAN
NC score	0.050304 (rank : 726)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	246	Target Neighborhood Hits	1023	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

MFAP1_MOUSE
NC score	0.050221 (rank : 727)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	246	Target Neighborhood Hits	353	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

PTK6_MOUSE
NC score	0.050184 (rank : 728)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	246	Target Neighborhood Hits	1026	Shared Neighborhood Hits	97
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

MYH1_MOUSE
NC score	0.050084 (rank : 729)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	246	Target Neighborhood Hits	1461	Shared Neighborhood Hits	71
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH3_HUMAN
NC score	0.050057 (rank : 730)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	246	Target Neighborhood Hits	1660	Shared Neighborhood Hits	76
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

SMC1A_HUMAN
NC score	0.050016 (rank : 731)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	246	Target Neighborhood Hits	1346	Shared Neighborhood Hits	66
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

N4BP3_HUMAN
NC score	0.050010 (rank : 732)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

TEX9_HUMAN
NC score	0.047213 (rank : 733)	θ value	0.813845 (rank : 157)
Query Neighborhood Hits	246	Target Neighborhood Hits	541	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TRAF3_HUMAN
NC score	0.047004 (rank : 734)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	246	Target Neighborhood Hits	463	Shared Neighborhood Hits	31
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
NC score	0.046837 (rank : 735)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	246	Target Neighborhood Hits	476	Shared Neighborhood Hits	32
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

JIP4_HUMAN
NC score	0.045944 (rank : 736)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	246	Target Neighborhood Hits	585	Shared Neighborhood Hits	40
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

NACAM_MOUSE
NC score	0.044309 (rank : 737)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	246	Target Neighborhood Hits	1866	Shared Neighborhood Hits	62
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ROS_HUMAN
NC score	0.043519 (rank : 738)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	246	Target Neighborhood Hits	907	Shared Neighborhood Hits	64
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

JIP4_MOUSE
NC score	0.043367 (rank : 739)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	246	Target Neighborhood Hits	593	Shared Neighborhood Hits	39
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

MACF4_HUMAN
NC score	0.042397 (rank : 740)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	246	Target Neighborhood Hits	1321	Shared Neighborhood Hits	63
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

STXB4_HUMAN
NC score	0.042189 (rank : 741)	θ value	1.06291 (rank : 162)
Query Neighborhood Hits	246	Target Neighborhood Hits	616	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DMD_HUMAN
NC score	0.041899 (rank : 742)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	246	Target Neighborhood Hits	1135	Shared Neighborhood Hits	55
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

SPC24_HUMAN
NC score	0.039988 (rank : 743)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

MILK1_MOUSE
NC score	0.039854 (rank : 744)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	246	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

YETS2_MOUSE
NC score	0.039707 (rank : 745)	θ value	1.38821 (rank : 170)
Query Neighborhood Hits	246	Target Neighborhood Hits	278	Shared Neighborhood Hits	12
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

STXB4_MOUSE
NC score	0.038203 (rank : 746)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	246	Target Neighborhood Hits	629	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

MACF1_HUMAN
NC score	0.037400 (rank : 747)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	246	Target Neighborhood Hits	1341	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

T53I2_MOUSE
NC score	0.036540 (rank : 748)	θ value	0.62314 (rank : 150)
Query Neighborhood Hits	246	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFU8, Q711P5, Q8CHM4	Gene names	Tp53inp2, Dor, Trp53inp2
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity- regulated protein).

PHLB2_MOUSE
NC score	0.036507 (rank : 749)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	246	Target Neighborhood Hits	1016	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PLCB2_HUMAN
NC score	0.036448 (rank : 750)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	246	Target Neighborhood Hits	608	Shared Neighborhood Hits	36
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

KIF14_HUMAN
NC score	0.035083 (rank : 751)	θ value	0.365318 (rank : 137)
Query Neighborhood Hits	246	Target Neighborhood Hits	732	Shared Neighborhood Hits	44
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

NASP_HUMAN
NC score	0.028921 (rank : 752)	θ value	1.81305 (rank : 178)
Query Neighborhood Hits	246	Target Neighborhood Hits	709	Shared Neighborhood Hits	31
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SNW1_HUMAN
NC score	0.026181 (rank : 753)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	246	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

SNW1_MOUSE
NC score	0.024947 (rank : 754)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	246	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

MBRL_HUMAN
NC score	0.024333 (rank : 755)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	246	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q4ZIN3, O60392, Q8NF79, Q96H30	Gene names	C19orf6
Domain Architecture	No domain graphic available
Description	Membralin.

DBF4_MOUSE
NC score	0.024107 (rank : 756)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	246	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ41, Q3TQP4, Q3V1K2, Q6NSQ1, Q9CXF2	Gene names	Dbf4
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (MuDBF4).

YTHD2_HUMAN
NC score	0.023715 (rank : 757)	θ value	0.365318 (rank : 139)
Query Neighborhood Hits	246	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

K2C1_HUMAN
NC score	0.023018 (rank : 758)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	246	Target Neighborhood Hits	624	Shared Neighborhood Hits	42
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

TDP2_MOUSE
NC score	0.020978 (rank : 759)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	246	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q64163	Gene names	Tfdp2, Dp2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2) (Dp-3).

SNPC4_MOUSE
NC score	0.019851 (rank : 760)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	246	Target Neighborhood Hits	237	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

K0256_HUMAN
NC score	0.018545 (rank : 761)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	246	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q93073, Q8N767	Gene names	KIAA0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

TDP2_HUMAN
NC score	0.018443 (rank : 762)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	246	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

TENS1_HUMAN
NC score	0.018309 (rank : 763)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	246	Target Neighborhood Hits	400	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

K0256_MOUSE
NC score	0.017706 (rank : 764)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	246	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

CS007_MOUSE
NC score	0.017584 (rank : 765)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	246	Target Neighborhood Hits	464	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

LRRK2_MOUSE
NC score	0.016931 (rank : 766)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	246	Target Neighborhood Hits	1359	Shared Neighborhood Hits	28
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

IWS1_MOUSE
NC score	0.015123 (rank : 767)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	246	Target Neighborhood Hits	1258	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PRP40_MOUSE
NC score	0.014302 (rank : 768)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	246	Target Neighborhood Hits	447	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

GLDN_MOUSE
NC score	0.014031 (rank : 769)	θ value	1.38821 (rank : 165)
Query Neighborhood Hits	246	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

IMPG1_HUMAN
NC score	0.013826 (rank : 770)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	246	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

PARG_MOUSE
NC score	0.013359 (rank : 771)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	246	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	O88622, Q80YQ6, Q8CB72	Gene names	Parg
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

TR240_HUMAN
NC score	0.011952 (rank : 772)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	246	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

NOS1_MOUSE
NC score	0.011754 (rank : 773)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	246	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

K0999_MOUSE
NC score	0.009504 (rank : 774)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	246	Target Neighborhood Hits	931	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

K0999_HUMAN
NC score	0.009390 (rank : 775)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	246	Target Neighborhood Hits	899	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

TPOR_HUMAN
NC score	0.009222 (rank : 776)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	246	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

ZFY16_MOUSE
NC score	0.007977 (rank : 777)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

NR1H4_MOUSE
NC score	0.006683 (rank : 778)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	246	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H4_HUMAN
NC score	0.005725 (rank : 779)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	246	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).