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Network neighborhood for query Sequence : ARHG1_MOUSE

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ARHG1_MOUSE
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARHG1_HUMAN
θ value	0 (rank : 1)	NC score	0.969890 (rank : 2)
Query Neighborhood Hits	266	Target Neighborhood Hits	176	Shared Neighborhood Hits	119
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	266	Target Neighborhood Hits	266	Shared Neighborhood Hits	266
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHGC_MOUSE
θ value	8.91014e-149 (rank : 3)	NC score	0.845988 (rank : 3)
Query Neighborhood Hits	266	Target Neighborhood Hits	344	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_HUMAN
θ value	1.28662e-147 (rank : 4)	NC score	0.842185 (rank : 5)
Query Neighborhood Hits	266	Target Neighborhood Hits	351	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGB_HUMAN
θ value	1.06975e-93 (rank : 5)	NC score	0.813101 (rank : 6)
Query Neighborhood Hits	266	Target Neighborhood Hits	375	Shared Neighborhood Hits	78
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

LBC_HUMAN
θ value	7.03111e-45 (rank : 6)	NC score	0.842877 (rank : 4)
Query Neighborhood Hits	266	Target Neighborhood Hits	90	Shared Neighborhood Hits	52
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

ARHG2_MOUSE
θ value	2.67802e-36 (rank : 7)	NC score	0.808646 (rank : 7)
Query Neighborhood Hits	266	Target Neighborhood Hits	120	Shared Neighborhood Hits	53
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG2_HUMAN
θ value	6.59618e-35 (rank : 8)	NC score	0.800198 (rank : 8)
Query Neighborhood Hits	266	Target Neighborhood Hits	142	Shared Neighborhood Hits	54
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

RGNEF_MOUSE
θ value	7.54701e-31 (rank : 9)	NC score	0.676855 (rank : 11)
Query Neighborhood Hits	266	Target Neighborhood Hits	641	Shared Neighborhood Hits	70
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ITSN2_HUMAN
θ value	3.62785e-25 (rank : 10)	NC score	0.463689 (rank : 35)
Query Neighborhood Hits	266	Target Neighborhood Hits	1173	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN1_HUMAN
θ value	5.23862e-24 (rank : 11)	NC score	0.425773 (rank : 51)
Query Neighborhood Hits	266	Target Neighborhood Hits	1757	Shared Neighborhood Hits	109
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_MOUSE
θ value	6.84181e-24 (rank : 12)	NC score	0.439738 (rank : 45)
Query Neighborhood Hits	266	Target Neighborhood Hits	1371	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITSN1_MOUSE
θ value	3.39556e-23 (rank : 13)	NC score	0.424776 (rank : 52)
Query Neighborhood Hits	266	Target Neighborhood Hits	1669	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ARHG3_MOUSE
θ value	3.07829e-16 (rank : 14)	NC score	0.683059 (rank : 9)
Query Neighborhood Hits	266	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ECT2_MOUSE
θ value	8.95645e-16 (rank : 15)	NC score	0.658344 (rank : 14)
Query Neighborhood Hits	266	Target Neighborhood Hits	98	Shared Neighborhood Hits	58
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ARHG3_HUMAN
θ value	1.16975e-15 (rank : 16)	NC score	0.682843 (rank : 10)
Query Neighborhood Hits	266	Target Neighborhood Hits	82	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

FGD4_MOUSE
θ value	1.16975e-15 (rank : 17)	NC score	0.541340 (rank : 25)
Query Neighborhood Hits	266	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD4_HUMAN
θ value	1.99529e-15 (rank : 18)	NC score	0.541446 (rank : 24)
Query Neighborhood Hits	266	Target Neighborhood Hits	219	Shared Neighborhood Hits	58
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

ARHG8_HUMAN
θ value	9.90251e-15 (rank : 19)	NC score	0.666952 (rank : 12)
Query Neighborhood Hits	266	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ECT2_HUMAN
θ value	9.90251e-15 (rank : 20)	NC score	0.642221 (rank : 18)
Query Neighborhood Hits	266	Target Neighborhood Hits	98	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ARHG8_MOUSE
θ value	2.88119e-14 (rank : 21)	NC score	0.650254 (rank : 15)
Query Neighborhood Hits	266	Target Neighborhood Hits	79	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

FGD3_MOUSE
θ value	1.42992e-13 (rank : 22)	NC score	0.564919 (rank : 22)
Query Neighborhood Hits	266	Target Neighborhood Hits	257	Shared Neighborhood Hits	68
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

NGEF_HUMAN
θ value	1.86753e-13 (rank : 23)	NC score	0.641787 (rank : 19)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHG5_HUMAN
θ value	3.18553e-13 (rank : 24)	NC score	0.647010 (rank : 17)
Query Neighborhood Hits	266	Target Neighborhood Hits	172	Shared Neighborhood Hits	58
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

VAV_MOUSE
θ value	9.26847e-13 (rank : 25)	NC score	0.462497 (rank : 37)
Query Neighborhood Hits	266	Target Neighborhood Hits	430	Shared Neighborhood Hits	62
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

NGEF_MOUSE
θ value	1.2105e-12 (rank : 26)	NC score	0.630160 (rank : 20)
Query Neighborhood Hits	266	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHGG_MOUSE
θ value	2.69671e-12 (rank : 27)	NC score	0.648908 (rank : 16)
Query Neighborhood Hits	266	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_HUMAN
θ value	4.59992e-12 (rank : 28)	NC score	0.658485 (rank : 13)
Query Neighborhood Hits	266	Target Neighborhood Hits	129	Shared Neighborhood Hits	58
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

VAV3_MOUSE
θ value	4.59992e-12 (rank : 29)	NC score	0.435345 (rank : 48)
Query Neighborhood Hits	266	Target Neighborhood Hits	404	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV3_HUMAN
θ value	6.00763e-12 (rank : 30)	NC score	0.435652 (rank : 47)
Query Neighborhood Hits	266	Target Neighborhood Hits	398	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	7.84624e-12 (rank : 31)	NC score	0.445741 (rank : 43)
Query Neighborhood Hits	266	Target Neighborhood Hits	452	Shared Neighborhood Hits	62
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ARHGF_HUMAN
θ value	1.02475e-11 (rank : 32)	NC score	0.619087 (rank : 21)
Query Neighborhood Hits	266	Target Neighborhood Hits	214	Shared Neighborhood Hits	75
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

FGD2_HUMAN
θ value	2.98157e-11 (rank : 33)	NC score	0.530007 (rank : 28)
Query Neighborhood Hits	266	Target Neighborhood Hits	151	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	1.133e-10 (rank : 34)	NC score	0.535221 (rank : 26)
Query Neighborhood Hits	266	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

VAV2_HUMAN
θ value	5.62301e-10 (rank : 35)	NC score	0.456893 (rank : 41)
Query Neighborhood Hits	266	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	5.62301e-10 (rank : 36)	NC score	0.457294 (rank : 40)
Query Neighborhood Hits	266	Target Neighborhood Hits	456	Shared Neighborhood Hits	71
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

TIAM1_HUMAN
θ value	1.25267e-09 (rank : 37)	NC score	0.525720 (rank : 30)
Query Neighborhood Hits	266	Target Neighborhood Hits	225	Shared Neighborhood Hits	61
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

FGD1_MOUSE
θ value	2.13673e-09 (rank : 38)	NC score	0.521609 (rank : 31)
Query Neighborhood Hits	266	Target Neighborhood Hits	387	Shared Neighborhood Hits	110
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD3_HUMAN
θ value	2.13673e-09 (rank : 39)	NC score	0.545154 (rank : 23)
Query Neighborhood Hits	266	Target Neighborhood Hits	249	Shared Neighborhood Hits	81
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

ARHGA_HUMAN
θ value	2.79066e-09 (rank : 40)	NC score	0.492686 (rank : 34)
Query Neighborhood Hits	266	Target Neighborhood Hits	187	Shared Neighborhood Hits	58
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

TIAM1_MOUSE
θ value	3.64472e-09 (rank : 41)	NC score	0.533093 (rank : 27)
Query Neighborhood Hits	266	Target Neighborhood Hits	205	Shared Neighborhood Hits	58
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARHGA_MOUSE
θ value	1.06045e-08 (rank : 42)	NC score	0.459931 (rank : 38)
Query Neighborhood Hits	266	Target Neighborhood Hits	125	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

FGD1_HUMAN
θ value	1.38499e-08 (rank : 43)	NC score	0.514783 (rank : 32)
Query Neighborhood Hits	266	Target Neighborhood Hits	367	Shared Neighborhood Hits	95
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PREX1_HUMAN
θ value	8.97725e-08 (rank : 44)	NC score	0.527458 (rank : 29)
Query Neighborhood Hits	266	Target Neighborhood Hits	177	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PKHG1_HUMAN
θ value	1.99992e-07 (rank : 45)	NC score	0.497172 (rank : 33)
Query Neighborhood Hits	266	Target Neighborhood Hits	174	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

FGD6_MOUSE
θ value	7.59969e-07 (rank : 46)	NC score	0.438391 (rank : 46)
Query Neighborhood Hits	266	Target Neighborhood Hits	282	Shared Neighborhood Hits	59
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD6_HUMAN
θ value	1.69304e-06 (rank : 47)	NC score	0.435148 (rank : 49)
Query Neighborhood Hits	266	Target Neighborhood Hits	237	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

MCF2_HUMAN
θ value	4.1701e-05 (rank : 48)	NC score	0.434182 (rank : 50)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	58
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

DNMBP_HUMAN
θ value	0.000121331 (rank : 49)	NC score	0.385555 (rank : 55)
Query Neighborhood Hits	266	Target Neighborhood Hits	413	Shared Neighborhood Hits	69
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SRRM2_MOUSE
θ value	0.00102713 (rank : 50)	NC score	0.066616 (rank : 244)
Query Neighborhood Hits	266	Target Neighborhood Hits	1470	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RPP25_HUMAN
θ value	0.00228821 (rank : 51)	NC score	0.074048 (rank : 197)
Query Neighborhood Hits	266	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BUL9, Q9NX88	Gene names	RPP25
Domain Architecture	No domain graphic available
Description	Ribonuclease P protein subunit p25 (EC 3.1.26.5) (RNase P protein subunit p25).

DNMBP_MOUSE
θ value	0.00298849 (rank : 52)	NC score	0.392524 (rank : 54)
Query Neighborhood Hits	266	Target Neighborhood Hits	435	Shared Neighborhood Hits	69
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FGD5_HUMAN
θ value	0.00390308 (rank : 53)	NC score	0.330456 (rank : 56)
Query Neighborhood Hits	266	Target Neighborhood Hits	235	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

DUET_HUMAN
θ value	0.00509761 (rank : 54)	NC score	0.150416 (rank : 71)
Query Neighborhood Hits	266	Target Neighborhood Hits	1220	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

CO8A2_HUMAN
θ value	0.00665767 (rank : 55)	NC score	0.107912 (rank : 105)
Query Neighborhood Hits	266	Target Neighborhood Hits	299	Shared Neighborhood Hits	75
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

FGD5_MOUSE
θ value	0.00665767 (rank : 56)	NC score	0.312525 (rank : 58)
Query Neighborhood Hits	266	Target Neighborhood Hits	170	Shared Neighborhood Hits	43
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

HAPIP_HUMAN
θ value	0.0113563 (rank : 57)	NC score	0.325337 (rank : 57)
Query Neighborhood Hits	266	Target Neighborhood Hits	350	Shared Neighborhood Hits	61
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

TRIO_HUMAN
θ value	0.0148317 (rank : 58)	NC score	0.139827 (rank : 72)
Query Neighborhood Hits	266	Target Neighborhood Hits	1580	Shared Neighborhood Hits	93
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

CO7A1_HUMAN
θ value	0.0193708 (rank : 59)	NC score	0.093587 (rank : 142)
Query Neighborhood Hits	266	Target Neighborhood Hits	807	Shared Neighborhood Hits	91
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COBA1_HUMAN
θ value	0.0193708 (rank : 60)	NC score	0.112261 (rank : 84)
Query Neighborhood Hits	266	Target Neighborhood Hits	491	Shared Neighborhood Hits	84
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

MAGC3_HUMAN
θ value	0.0193708 (rank : 61)	NC score	0.031920 (rank : 390)
Query Neighborhood Hits	266	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

PRG4_HUMAN
θ value	0.0193708 (rank : 62)	NC score	0.048259 (rank : 355)
Query Neighborhood Hits	266	Target Neighborhood Hits	764	Shared Neighborhood Hits	56
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CO5A1_MOUSE
θ value	0.0252991 (rank : 63)	NC score	0.116565 (rank : 80)
Query Neighborhood Hits	266	Target Neighborhood Hits	419	Shared Neighborhood Hits	84
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

TCOF_MOUSE
θ value	0.0252991 (rank : 64)	NC score	0.055607 (rank : 299)
Query Neighborhood Hits	266	Target Neighborhood Hits	471	Shared Neighborhood Hits	39
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

CO5A1_HUMAN
θ value	0.0330416 (rank : 65)	NC score	0.114421 (rank : 82)
Query Neighborhood Hits	266	Target Neighborhood Hits	434	Shared Neighborhood Hits	87
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

COGA1_HUMAN
θ value	0.0330416 (rank : 66)	NC score	0.103930 (rank : 116)
Query Neighborhood Hits	266	Target Neighborhood Hits	345	Shared Neighborhood Hits	74
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

MLL2_HUMAN
θ value	0.0330416 (rank : 67)	NC score	0.072894 (rank : 204)
Query Neighborhood Hits	266	Target Neighborhood Hits	1788	Shared Neighborhood Hits	134
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SREC2_MOUSE
θ value	0.0330416 (rank : 68)	NC score	0.011716 (rank : 459)
Query Neighborhood Hits	266	Target Neighborhood Hits	605	Shared Neighborhood Hits	23
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ZMYM3_MOUSE
θ value	0.0330416 (rank : 69)	NC score	0.035093 (rank : 382)
Query Neighborhood Hits	266	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

CO6A2_MOUSE
θ value	0.0431538 (rank : 70)	NC score	0.104641 (rank : 114)
Query Neighborhood Hits	266	Target Neighborhood Hits	260	Shared Neighborhood Hits	66
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO8A1_HUMAN
θ value	0.0431538 (rank : 71)	NC score	0.108258 (rank : 103)
Query Neighborhood Hits	266	Target Neighborhood Hits	288	Shared Neighborhood Hits	71
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

BCL9_MOUSE
θ value	0.0563607 (rank : 72)	NC score	0.091511 (rank : 144)
Query Neighborhood Hits	266	Target Neighborhood Hits	770	Shared Neighborhood Hits	111
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CO4A5_HUMAN
θ value	0.0563607 (rank : 73)	NC score	0.110514 (rank : 92)
Query Neighborhood Hits	266	Target Neighborhood Hits	383	Shared Neighborhood Hits	88
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

PRG4_MOUSE
θ value	0.0563607 (rank : 74)	NC score	0.042904 (rank : 364)
Query Neighborhood Hits	266	Target Neighborhood Hits	624	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CO8A1_MOUSE
θ value	0.0736092 (rank : 75)	NC score	0.105482 (rank : 108)
Query Neighborhood Hits	266	Target Neighborhood Hits	251	Shared Neighborhood Hits	68
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

COBA1_MOUSE
θ value	0.0961366 (rank : 76)	NC score	0.111590 (rank : 86)
Query Neighborhood Hits	266	Target Neighborhood Hits	487	Shared Neighborhood Hits	85
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COHA1_MOUSE
θ value	0.0961366 (rank : 77)	NC score	0.102039 (rank : 125)
Query Neighborhood Hits	266	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

FMNL_HUMAN
θ value	0.0961366 (rank : 78)	NC score	0.037399 (rank : 377)
Query Neighborhood Hits	266	Target Neighborhood Hits	529	Shared Neighborhood Hits	50
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

MCF2L_MOUSE
θ value	0.0961366 (rank : 79)	NC score	0.399912 (rank : 53)
Query Neighborhood Hits	266	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

BCL7C_MOUSE
θ value	0.125558 (rank : 80)	NC score	0.044068 (rank : 363)
Query Neighborhood Hits	266	Target Neighborhood Hits	170	Shared Neighborhood Hits	43
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

BCR_HUMAN
θ value	0.125558 (rank : 81)	NC score	0.253980 (rank : 65)
Query Neighborhood Hits	266	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CO8A2_MOUSE
θ value	0.125558 (rank : 82)	NC score	0.100596 (rank : 129)
Query Neighborhood Hits	266	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

MAGC1_HUMAN
θ value	0.125558 (rank : 83)	NC score	0.032037 (rank : 389)
Query Neighborhood Hits	266	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

CO1A1_MOUSE
θ value	0.163984 (rank : 84)	NC score	0.103607 (rank : 117)
Query Neighborhood Hits	266	Target Neighborhood Hits	457	Shared Neighborhood Hits	85
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
θ value	0.163984 (rank : 85)	NC score	0.103596 (rank : 118)
Query Neighborhood Hits	266	Target Neighborhood Hits	452	Shared Neighborhood Hits	87
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MADCA_HUMAN
θ value	0.163984 (rank : 86)	NC score	0.042570 (rank : 366)
Query Neighborhood Hits	266	Target Neighborhood Hits	221	Shared Neighborhood Hits	23
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

CO3A1_MOUSE
θ value	0.21417 (rank : 87)	NC score	0.104265 (rank : 115)
Query Neighborhood Hits	266	Target Neighborhood Hits	466	Shared Neighborhood Hits	83
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

LATS2_HUMAN
θ value	0.279714 (rank : 88)	NC score	0.001982 (rank : 488)
Query Neighborhood Hits	266	Target Neighborhood Hits	884	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

MLL4_HUMAN
θ value	0.279714 (rank : 89)	NC score	0.036021 (rank : 380)
Query Neighborhood Hits	266	Target Neighborhood Hits	722	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

OGFR_HUMAN
θ value	0.279714 (rank : 90)	NC score	0.095681 (rank : 137)
Query Neighborhood Hits	266	Target Neighborhood Hits	1582	Shared Neighborhood Hits	158
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CONA1_MOUSE
θ value	0.365318 (rank : 91)	NC score	0.111469 (rank : 87)
Query Neighborhood Hits	266	Target Neighborhood Hits	254	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

RGS3_HUMAN
θ value	0.365318 (rank : 92)	NC score	0.081000 (rank : 165)
Query Neighborhood Hits	266	Target Neighborhood Hits	1375	Shared Neighborhood Hits	147
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RP3A_HUMAN
θ value	0.365318 (rank : 93)	NC score	0.036206 (rank : 379)
Query Neighborhood Hits	266	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

XRCC1_MOUSE
θ value	0.365318 (rank : 94)	NC score	0.031678 (rank : 391)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

CAH9_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.011684 (rank : 460)
Query Neighborhood Hits	266	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHB5, Q8K1G1, Q8VDE4	Gene names	Ca9, Car9
Domain Architecture
Description	Carbonic anhydrase 9 precursor (EC 4.2.1.1) (Carbonic anhydrase IX) (Carbonate dehydratase IX) (CA-IX) (CAIX) (Membrane antigen MN homolog).

CENG2_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.013862 (rank : 448)
Query Neighborhood Hits	266	Target Neighborhood Hits	471	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CO1A1_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.105391 (rank : 110)
Query Neighborhood Hits	266	Target Neighborhood Hits	475	Shared Neighborhood Hits	87
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO4A1_HUMAN
θ value	0.47712 (rank : 98)	NC score	0.109141 (rank : 98)
Query Neighborhood Hits	266	Target Neighborhood Hits	425	Shared Neighborhood Hits	84
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A1_MOUSE
θ value	0.47712 (rank : 99)	NC score	0.110067 (rank : 94)
Query Neighborhood Hits	266	Target Neighborhood Hits	450	Shared Neighborhood Hits	87
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A2_HUMAN
θ value	0.47712 (rank : 100)	NC score	0.111863 (rank : 85)
Query Neighborhood Hits	266	Target Neighborhood Hits	454	Shared Neighborhood Hits	86
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO5A2_HUMAN
θ value	0.47712 (rank : 101)	NC score	0.104898 (rank : 113)
Query Neighborhood Hits	266	Target Neighborhood Hits	760	Shared Neighborhood Hits	102
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO6A1_MOUSE
θ value	0.47712 (rank : 102)	NC score	0.093206 (rank : 143)
Query Neighborhood Hits	266	Target Neighborhood Hits	241	Shared Neighborhood Hits	56
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

SAPS1_HUMAN
θ value	0.47712 (rank : 103)	NC score	0.046987 (rank : 356)
Query Neighborhood Hits	266	Target Neighborhood Hits	704	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CO4A4_HUMAN
θ value	0.62314 (rank : 104)	NC score	0.102872 (rank : 120)
Query Neighborhood Hits	266	Target Neighborhood Hits	440	Shared Neighborhood Hits	80
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

COHA1_HUMAN
θ value	0.62314 (rank : 105)	NC score	0.101363 (rank : 127)
Query Neighborhood Hits	266	Target Neighborhood Hits	400	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COIA1_HUMAN
θ value	0.62314 (rank : 106)	NC score	0.089644 (rank : 147)
Query Neighborhood Hits	266	Target Neighborhood Hits	447	Shared Neighborhood Hits	83
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

MUCDL_HUMAN
θ value	0.62314 (rank : 107)	NC score	0.037407 (rank : 376)
Query Neighborhood Hits	266	Target Neighborhood Hits	777	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ABR_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.243670 (rank : 69)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	54
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

CBP_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.034258 (rank : 385)
Query Neighborhood Hits	266	Target Neighborhood Hits	941	Shared Neighborhood Hits	83
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CO4A3_HUMAN
θ value	0.813845 (rank : 110)	NC score	0.105408 (rank : 109)
Query Neighborhood Hits	266	Target Neighborhood Hits	421	Shared Neighborhood Hits	77
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

COBA2_MOUSE
θ value	0.813845 (rank : 111)	NC score	0.108895 (rank : 100)
Query Neighborhood Hits	266	Target Neighborhood Hits	501	Shared Neighborhood Hits	84
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CS007_HUMAN
θ value	0.813845 (rank : 112)	NC score	0.029634 (rank : 395)
Query Neighborhood Hits	266	Target Neighborhood Hits	401	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DREB_HUMAN
θ value	0.813845 (rank : 113)	NC score	0.034202 (rank : 386)
Query Neighborhood Hits	266	Target Neighborhood Hits	450	Shared Neighborhood Hits	26
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

EMID1_MOUSE
θ value	0.813845 (rank : 114)	NC score	0.083498 (rank : 157)
Query Neighborhood Hits	266	Target Neighborhood Hits	230	Shared Neighborhood Hits	61
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EVPL_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.038374 (rank : 374)
Query Neighborhood Hits	266	Target Neighborhood Hits	895	Shared Neighborhood Hits	31
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

MUCDL_MOUSE
θ value	0.813845 (rank : 116)	NC score	0.026333 (rank : 402)
Query Neighborhood Hits	266	Target Neighborhood Hits	461	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

OGFR_MOUSE
θ value	0.813845 (rank : 117)	NC score	0.107348 (rank : 107)
Query Neighborhood Hits	266	Target Neighborhood Hits	584	Shared Neighborhood Hits	99
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PCLO_HUMAN
θ value	0.813845 (rank : 118)	NC score	0.060395 (rank : 271)
Query Neighborhood Hits	266	Target Neighborhood Hits	2046	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RB15B_MOUSE
θ value	0.813845 (rank : 119)	NC score	0.016712 (rank : 433)
Query Neighborhood Hits	266	Target Neighborhood Hits	284	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SPEG_MOUSE
θ value	0.813845 (rank : 120)	NC score	0.008018 (rank : 476)
Query Neighborhood Hits	266	Target Neighborhood Hits	1959	Shared Neighborhood Hits	91
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

BCL9_HUMAN
θ value	1.06291 (rank : 121)	NC score	0.076723 (rank : 183)
Query Neighborhood Hits	266	Target Neighborhood Hits	1008	Shared Neighborhood Hits	119
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CBX6_HUMAN
θ value	1.06291 (rank : 122)	NC score	0.021169 (rank : 415)
Query Neighborhood Hits	266	Target Neighborhood Hits	104	Shared Neighborhood Hits	17
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CCD96_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.046489 (rank : 359)
Query Neighborhood Hits	266	Target Neighborhood Hits	595	Shared Neighborhood Hits	39
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CENG2_MOUSE
θ value	1.06291 (rank : 124)	NC score	0.013117 (rank : 455)
Query Neighborhood Hits	266	Target Neighborhood Hits	463	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

COBA2_HUMAN
θ value	1.06291 (rank : 125)	NC score	0.110565 (rank : 91)
Query Neighborhood Hits	266	Target Neighborhood Hits	408	Shared Neighborhood Hits	77
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COCA1_MOUSE
θ value	1.06291 (rank : 126)	NC score	0.057825 (rank : 285)
Query Neighborhood Hits	266	Target Neighborhood Hits	467	Shared Neighborhood Hits	69
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	1.06291 (rank : 127)	NC score	0.072753 (rank : 205)
Query Neighborhood Hits	266	Target Neighborhood Hits	427	Shared Neighborhood Hits	64
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CONA1_HUMAN
θ value	1.06291 (rank : 128)	NC score	0.107526 (rank : 106)
Query Neighborhood Hits	266	Target Neighborhood Hits	281	Shared Neighborhood Hits	71
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

FOXP4_HUMAN
θ value	1.06291 (rank : 129)	NC score	0.008899 (rank : 471)
Query Neighborhood Hits	266	Target Neighborhood Hits	246	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

N4BP2_HUMAN
θ value	1.06291 (rank : 130)	NC score	0.045503 (rank : 361)
Query Neighborhood Hits	266	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

SET1A_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.041994 (rank : 367)
Query Neighborhood Hits	266	Target Neighborhood Hits	690	Shared Neighborhood Hits	51
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SFPQ_HUMAN
θ value	1.06291 (rank : 132)	NC score	0.036398 (rank : 378)
Query Neighborhood Hits	266	Target Neighborhood Hits	986	Shared Neighborhood Hits	79
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

CO6A2_HUMAN
θ value	1.38821 (rank : 133)	NC score	0.102698 (rank : 121)
Query Neighborhood Hits	266	Target Neighborhood Hits	249	Shared Neighborhood Hits	63
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

COEA1_MOUSE
θ value	1.38821 (rank : 134)	NC score	0.065856 (rank : 248)
Query Neighborhood Hits	266	Target Neighborhood Hits	402	Shared Neighborhood Hits	66
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COIA1_MOUSE
θ value	1.38821 (rank : 135)	NC score	0.091098 (rank : 145)
Query Neighborhood Hits	266	Target Neighborhood Hits	481	Shared Neighborhood Hits	83
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

HXA3_MOUSE
θ value	1.38821 (rank : 136)	NC score	0.008915 (rank : 470)
Query Neighborhood Hits	266	Target Neighborhood Hits	558	Shared Neighborhood Hits	34
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

SALL3_HUMAN
θ value	1.38821 (rank : 137)	NC score	0.003277 (rank : 487)
Query Neighborhood Hits	266	Target Neighborhood Hits	1066	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

TCF20_MOUSE
θ value	1.38821 (rank : 138)	NC score	0.032821 (rank : 388)
Query Neighborhood Hits	266	Target Neighborhood Hits	396	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TTC28_MOUSE
θ value	1.38821 (rank : 139)	NC score	0.015446 (rank : 440)
Query Neighborhood Hits	266	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

CAF1B_MOUSE
θ value	1.81305 (rank : 140)	NC score	0.010061 (rank : 465)
Query Neighborhood Hits	266	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CBP_MOUSE
θ value	1.81305 (rank : 141)	NC score	0.030948 (rank : 392)
Query Neighborhood Hits	266	Target Neighborhood Hits	1051	Shared Neighborhood Hits	81
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CF152_MOUSE
θ value	1.81305 (rank : 142)	NC score	0.022054 (rank : 411)
Query Neighborhood Hits	266	Target Neighborhood Hits	597	Shared Neighborhood Hits	23
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CO2A1_HUMAN
θ value	1.81305 (rank : 143)	NC score	0.103311 (rank : 119)
Query Neighborhood Hits	266	Target Neighborhood Hits	486	Shared Neighborhood Hits	83
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

HCN2_HUMAN
θ value	1.81305 (rank : 144)	NC score	0.020702 (rank : 416)
Query Neighborhood Hits	266	Target Neighborhood Hits	369	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

I17RD_HUMAN
θ value	1.81305 (rank : 145)	NC score	0.016796 (rank : 432)
Query Neighborhood Hits	266	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFM7, Q58EZ7, Q6RVF4, Q6UWI5, Q8N113, Q8NFS0, Q9UFA0	Gene names	IL17RD, IL17RLM, SEF
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor D precursor (IL-17 receptor D) (IL-17RD) (Interleukin-17D receptor) (IL-17D receptor) (IL17Rhom) (Interleukin- 17 receptor-like protein) (Sef homolog) (hSef).

IF35_MOUSE
θ value	1.81305 (rank : 146)	NC score	0.029692 (rank : 394)
Query Neighborhood Hits	266	Target Neighborhood Hits	210	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

MYBPH_MOUSE
θ value	1.81305 (rank : 147)	NC score	0.016085 (rank : 436)
Query Neighborhood Hits	266	Target Neighborhood Hits	290	Shared Neighborhood Hits	14
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

OSBL5_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.016146 (rank : 434)
Query Neighborhood Hits	266	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

PRDM8_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.008011 (rank : 477)
Query Neighborhood Hits	266	Target Neighborhood Hits	591	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQV8, Q6IQ36	Gene names	PRDM8, PFM5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

RPGF1_HUMAN
θ value	1.81305 (rank : 150)	NC score	0.017435 (rank : 425)
Query Neighborhood Hits	266	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SEM6C_MOUSE
θ value	1.81305 (rank : 151)	NC score	0.013154 (rank : 454)
Query Neighborhood Hits	266	Target Neighborhood Hits	352	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SHC1_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.042590 (rank : 365)
Query Neighborhood Hits	266	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	1.81305 (rank : 153)	NC score	0.038352 (rank : 375)
Query Neighborhood Hits	266	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SPN90_HUMAN
θ value	1.81305 (rank : 154)	NC score	0.040038 (rank : 370)
Query Neighborhood Hits	266	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SYNE2_HUMAN
θ value	1.81305 (rank : 155)	NC score	0.026555 (rank : 401)
Query Neighborhood Hits	266	Target Neighborhood Hits	1323	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TITIN_HUMAN
θ value	1.81305 (rank : 156)	NC score	0.008684 (rank : 474)
Query Neighborhood Hits	266	Target Neighborhood Hits	2923	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CO4A2_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.110094 (rank : 93)
Query Neighborhood Hits	266	Target Neighborhood Hits	492	Shared Neighborhood Hits	89
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COCA1_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.058205 (rank : 280)
Query Neighborhood Hits	266	Target Neighborhood Hits	458	Shared Neighborhood Hits	70
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ENAH_HUMAN
θ value	2.36792 (rank : 159)	NC score	0.048369 (rank : 354)
Query Neighborhood Hits	266	Target Neighborhood Hits	784	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	2.36792 (rank : 160)	NC score	0.048487 (rank : 352)
Query Neighborhood Hits	266	Target Neighborhood Hits	919	Shared Neighborhood Hits	61
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

NFAC1_HUMAN
θ value	2.36792 (rank : 161)	NC score	0.013652 (rank : 450)
Query Neighborhood Hits	266	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NUCKS_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.021174 (rank : 413)
Query Neighborhood Hits	266	Target Neighborhood Hits	143	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PHF1_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.015008 (rank : 443)
Query Neighborhood Hits	266	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PML_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.015412 (rank : 441)
Query Neighborhood Hits	266	Target Neighborhood Hits	248	Shared Neighborhood Hits	20
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TCGAP_MOUSE
θ value	2.36792 (rank : 165)	NC score	0.063133 (rank : 258)
Query Neighborhood Hits	266	Target Neighborhood Hits	409	Shared Neighborhood Hits	55
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TOIP2_HUMAN
θ value	2.36792 (rank : 166)	NC score	0.014159 (rank : 446)
Query Neighborhood Hits	266	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

TXND2_HUMAN
θ value	2.36792 (rank : 167)	NC score	0.038728 (rank : 373)
Query Neighborhood Hits	266	Target Neighborhood Hits	793	Shared Neighborhood Hits	55
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ATBF1_MOUSE
θ value	3.0926 (rank : 168)	NC score	0.011621 (rank : 462)
Query Neighborhood Hits	266	Target Neighborhood Hits	1841	Shared Neighborhood Hits	72
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATS14_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.013676 (rank : 449)
Query Neighborhood Hits	266	Target Neighborhood Hits	382	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

CAF1B_HUMAN
θ value	3.0926 (rank : 170)	NC score	0.008552 (rank : 475)
Query Neighborhood Hits	266	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

CEL_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.045098 (rank : 362)
Query Neighborhood Hits	266	Target Neighborhood Hits	896	Shared Neighborhood Hits	115
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CIC_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.039034 (rank : 371)
Query Neighborhood Hits	266	Target Neighborhood Hits	992	Shared Neighborhood Hits	100
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	3.0926 (rank : 173)	NC score	0.028608 (rank : 396)
Query Neighborhood Hits	266	Target Neighborhood Hits	742	Shared Neighborhood Hits	87
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO6A1_HUMAN
θ value	3.0926 (rank : 174)	NC score	0.097276 (rank : 135)
Query Neighborhood Hits	266	Target Neighborhood Hits	264	Shared Neighborhood Hits	64
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

COAA1_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.093995 (rank : 141)
Query Neighborhood Hits	266	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COG8_MOUSE
θ value	3.0926 (rank : 176)	NC score	0.021510 (rank : 412)
Query Neighborhood Hits	266	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

COJA1_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.101699 (rank : 126)
Query Neighborhood Hits	266	Target Neighborhood Hits	323	Shared Neighborhood Hits	68
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CS029_MOUSE
θ value	3.0926 (rank : 178)	NC score	0.023911 (rank : 408)
Query Neighborhood Hits	266	Target Neighborhood Hits	201	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

GRIN1_HUMAN
θ value	3.0926 (rank : 179)	NC score	0.078899 (rank : 174)
Query Neighborhood Hits	266	Target Neighborhood Hits	681	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GSCR1_HUMAN
θ value	3.0926 (rank : 180)	NC score	0.034291 (rank : 384)
Query Neighborhood Hits	266	Target Neighborhood Hits	674	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HCN4_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.013518 (rank : 451)
Query Neighborhood Hits	266	Target Neighborhood Hits	303	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

IASPP_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.050939 (rank : 335)
Query Neighborhood Hits	266	Target Neighborhood Hits	688	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MINT_MOUSE
θ value	3.0926 (rank : 183)	NC score	0.046922 (rank : 357)
Query Neighborhood Hits	266	Target Neighborhood Hits	1514	Shared Neighborhood Hits	108
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MRCKG_MOUSE
θ value	3.0926 (rank : 184)	NC score	0.008762 (rank : 472)
Query Neighborhood Hits	266	Target Neighborhood Hits	1466	Shared Neighborhood Hits	37
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

PITM3_MOUSE
θ value	3.0926 (rank : 185)	NC score	0.016135 (rank : 435)
Query Neighborhood Hits	266	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

RB6I2_HUMAN
θ value	3.0926 (rank : 186)	NC score	0.027110 (rank : 399)
Query Neighborhood Hits	266	Target Neighborhood Hits	1584	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	3.0926 (rank : 187)	NC score	0.028498 (rank : 397)
Query Neighborhood Hits	266	Target Neighborhood Hits	1433	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SFPQ_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.033974 (rank : 387)
Query Neighborhood Hits	266	Target Neighborhood Hits	958	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

TCAL8_MOUSE
θ value	3.0926 (rank : 189)	NC score	0.019408 (rank : 418)
Query Neighborhood Hits	266	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZY2, Q9CYP9	Gene names	Tceal8
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 8 (TCEA-like protein 8) (Transcription elongation factor S-II protein-like 8).

TFE3_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.017031 (rank : 429)
Query Neighborhood Hits	266	Target Neighborhood Hits	190	Shared Neighborhood Hits	11
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

ZN385_HUMAN
θ value	3.0926 (rank : 191)	NC score	0.080002 (rank : 168)
Query Neighborhood Hits	266	Target Neighborhood Hits	614	Shared Neighborhood Hits	109
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ADDB_MOUSE
θ value	4.03905 (rank : 192)	NC score	0.015977 (rank : 438)
Query Neighborhood Hits	266	Target Neighborhood Hits	574	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ARI5B_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.015613 (rank : 439)
Query Neighborhood Hits	266	Target Neighborhood Hits	328	Shared Neighborhood Hits	20
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

CHD4_MOUSE
θ value	4.03905 (rank : 194)	NC score	0.007980 (rank : 478)
Query Neighborhood Hits	266	Target Neighborhood Hits	408	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CO9A2_MOUSE
θ value	4.03905 (rank : 195)	NC score	0.100763 (rank : 128)
Query Neighborhood Hits	266	Target Neighborhood Hits	279	Shared Neighborhood Hits	68
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CSKI1_MOUSE
θ value	4.03905 (rank : 196)	NC score	0.018070 (rank : 422)
Query Neighborhood Hits	266	Target Neighborhood Hits	1031	Shared Neighborhood Hits	88
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CXXC6_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.021173 (rank : 414)
Query Neighborhood Hits	266	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

FA13C_MOUSE
θ value	4.03905 (rank : 198)	NC score	0.017354 (rank : 427)
Query Neighborhood Hits	266	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GANAB_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.007394 (rank : 479)
Query Neighborhood Hits	266	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

HRX_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.046566 (rank : 358)
Query Neighborhood Hits	266	Target Neighborhood Hits	825	Shared Neighborhood Hits	58
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

JPH2_HUMAN
θ value	4.03905 (rank : 201)	NC score	0.034391 (rank : 383)
Query Neighborhood Hits	266	Target Neighborhood Hits	639	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LAP2B_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.018564 (rank : 420)
Query Neighborhood Hits	266	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42167, Q14861	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

LARP1_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.016924 (rank : 430)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

MARCO_MOUSE
θ value	4.03905 (rank : 204)	NC score	0.089229 (rank : 148)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

NCOA5_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.025251 (rank : 404)
Query Neighborhood Hits	266	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

OSBL5_MOUSE
θ value	4.03905 (rank : 206)	NC score	0.013168 (rank : 453)
Query Neighborhood Hits	266	Target Neighborhood Hits	77	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

RC3H1_MOUSE
θ value	4.03905 (rank : 207)	NC score	0.008698 (rank : 473)
Query Neighborhood Hits	266	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RP1L1_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.045884 (rank : 360)
Query Neighborhood Hits	266	Target Neighborhood Hits	1072	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SSBP3_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.024893 (rank : 405)
Query Neighborhood Hits	266	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	4.03905 (rank : 210)	NC score	0.024893 (rank : 406)
Query Neighborhood Hits	266	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

THAP4_MOUSE
θ value	4.03905 (rank : 211)	NC score	0.014597 (rank : 444)
Query Neighborhood Hits	266	Target Neighborhood Hits	130	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

ZIMP7_MOUSE
θ value	4.03905 (rank : 212)	NC score	0.049221 (rank : 351)
Query Neighborhood Hits	266	Target Neighborhood Hits	566	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

BAT2_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.040759 (rank : 369)
Query Neighborhood Hits	266	Target Neighborhood Hits	947	Shared Neighborhood Hits	106
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO2A1_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.099759 (rank : 131)
Query Neighborhood Hits	266	Target Neighborhood Hits	483	Shared Neighborhood Hits	81
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

COKA1_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.065218 (rank : 251)
Query Neighborhood Hits	266	Target Neighborhood Hits	403	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CP250_HUMAN
θ value	5.27518 (rank : 216)	NC score	0.039026 (rank : 372)
Query Neighborhood Hits	266	Target Neighborhood Hits	1805	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CSKI2_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.016080 (rank : 437)
Query Neighborhood Hits	266	Target Neighborhood Hits	747	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FBX34_MOUSE
θ value	5.27518 (rank : 218)	NC score	0.011400 (rank : 463)
Query Neighborhood Hits	266	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

K0310_HUMAN
θ value	5.27518 (rank : 219)	NC score	0.030594 (rank : 393)
Query Neighborhood Hits	266	Target Neighborhood Hits	420	Shared Neighborhood Hits	51
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

LRC50_HUMAN
θ value	5.27518 (rank : 220)	NC score	0.016827 (rank : 431)
Query Neighborhood Hits	266	Target Neighborhood Hits	275	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

NASP_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.018609 (rank : 419)
Query Neighborhood Hits	266	Target Neighborhood Hits	709	Shared Neighborhood Hits	35
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCA11_MOUSE
θ value	5.27518 (rank : 222)	NC score	0.008948 (rank : 469)
Query Neighborhood Hits	266	Target Neighborhood Hits	661	Shared Neighborhood Hits	41
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PAK4_HUMAN
θ value	5.27518 (rank : 223)	NC score	-0.001059 (rank : 492)
Query Neighborhood Hits	266	Target Neighborhood Hits	924	Shared Neighborhood Hits	29
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PIAS4_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.007356 (rank : 481)
Query Neighborhood Hits	266	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

PITM3_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.012951 (rank : 456)
Query Neighborhood Hits	266	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZ71, Q59GH9, Q9NPQ4	Gene names	PITPNM3, NIR1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

PLXB1_MOUSE
θ value	5.27518 (rank : 226)	NC score	0.009081 (rank : 467)
Query Neighborhood Hits	266	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PODXL_HUMAN
θ value	5.27518 (rank : 227)	NC score	0.015033 (rank : 442)
Query Neighborhood Hits	266	Target Neighborhood Hits	191	Shared Neighborhood Hits	11
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RERE_MOUSE
θ value	5.27518 (rank : 228)	NC score	0.022323 (rank : 409)
Query Neighborhood Hits	266	Target Neighborhood Hits	785	Shared Neighborhood Hits	51
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SRPK2_MOUSE
θ value	5.27518 (rank : 229)	NC score	0.007359 (rank : 480)
Query Neighborhood Hits	266	Target Neighborhood Hits	765	Shared Neighborhood Hits	21
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

SYP2L_MOUSE
θ value	5.27518 (rank : 230)	NC score	0.041280 (rank : 368)
Query Neighborhood Hits	266	Target Neighborhood Hits	289	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TCF20_HUMAN
θ value	5.27518 (rank : 231)	NC score	0.028340 (rank : 398)
Query Neighborhood Hits	266	Target Neighborhood Hits	323	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

ZN598_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.017355 (rank : 426)
Query Neighborhood Hits	266	Target Neighborhood Hits	339	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ATN1_HUMAN
θ value	6.88961 (rank : 233)	NC score	0.026916 (rank : 400)
Query Neighborhood Hits	266	Target Neighborhood Hits	676	Shared Neighborhood Hits	56
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CF152_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.025291 (rank : 403)
Query Neighborhood Hits	266	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CK042_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.022134 (rank : 410)
Query Neighborhood Hits	266	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N5U0	Gene names	C11orf42
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf42.

CP250_MOUSE
θ value	6.88961 (rank : 236)	NC score	0.036000 (rank : 381)
Query Neighborhood Hits	266	Target Neighborhood Hits	1583	Shared Neighborhood Hits	49
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CSKI1_HUMAN
θ value	6.88961 (rank : 237)	NC score	0.017612 (rank : 424)
Query Neighborhood Hits	266	Target Neighborhood Hits	997	Shared Neighborhood Hits	108
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CUTL1_HUMAN
θ value	6.88961 (rank : 238)	NC score	0.024279 (rank : 407)
Query Neighborhood Hits	266	Target Neighborhood Hits	1574	Shared Neighborhood Hits	64
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

FRAS1_MOUSE
θ value	6.88961 (rank : 239)	NC score	0.004145 (rank : 485)
Query Neighborhood Hits	266	Target Neighborhood Hits	747	Shared Neighborhood Hits	15
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

JPH4_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.008966 (rank : 468)
Query Neighborhood Hits	266	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	Q96JJ6, Q8ND44, Q96DQ0	Gene names	JPH4, JPHL1, KIAA1831
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

KIF5C_HUMAN
θ value	6.88961 (rank : 241)	NC score	0.012690 (rank : 457)
Query Neighborhood Hits	266	Target Neighborhood Hits	974	Shared Neighborhood Hits	32
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MAGE1_HUMAN
θ value	6.88961 (rank : 242)	NC score	0.048478 (rank : 353)
Query Neighborhood Hits	266	Target Neighborhood Hits	1389	Shared Neighborhood Hits	133
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MK15_HUMAN
θ value	6.88961 (rank : 243)	NC score	-0.001409 (rank : 493)
Query Neighborhood Hits	266	Target Neighborhood Hits	1038	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

NEUM_MOUSE
θ value	6.88961 (rank : 244)	NC score	0.018483 (rank : 421)
Query Neighborhood Hits	266	Target Neighborhood Hits	149	Shared Neighborhood Hits	18
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

OXRP_HUMAN
θ value	6.88961 (rank : 245)	NC score	0.012091 (rank : 458)
Query Neighborhood Hits	266	Target Neighborhood Hits	544	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PCLO_MOUSE
θ value	6.88961 (rank : 246)	NC score	0.063115 (rank : 259)
Query Neighborhood Hits	266	Target Neighborhood Hits	2275	Shared Neighborhood Hits	157
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PO2F1_MOUSE
θ value	6.88961 (rank : 247)	NC score	0.003517 (rank : 486)
Query Neighborhood Hits	266	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

PO3F2_MOUSE
θ value	6.88961 (rank : 248)	NC score	0.005390 (rank : 483)
Query Neighborhood Hits	266	Target Neighborhood Hits	313	Shared Neighborhood Hits	10
SwissProt Accessions	P31360	Gene names	Pou3f2, Brn-2, Brn2, Otf7
Domain Architecture
Description	POU domain, class 3, transcription factor 2 (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Protein Brn-2).

RTN4_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.014333 (rank : 445)
Query Neighborhood Hits	266	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SFRS8_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.019928 (rank : 417)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SMCA4_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.013940 (rank : 447)
Query Neighborhood Hits	266	Target Neighborhood Hits	597	Shared Neighborhood Hits	47
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

APLP1_MOUSE
θ value	8.99809 (rank : 252)	NC score	0.018016 (rank : 423)
Query Neighborhood Hits	266	Target Neighborhood Hits	130	Shared Neighborhood Hits	16
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

CDAN1_HUMAN
θ value	8.99809 (rank : 253)	NC score	0.013462 (rank : 452)
Query Neighborhood Hits	266	Target Neighborhood Hits	92	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

CO5A3_HUMAN
θ value	8.99809 (rank : 254)	NC score	0.108091 (rank : 104)
Query Neighborhood Hits	266	Target Neighborhood Hits	433	Shared Neighborhood Hits	84
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CSPG3_MOUSE
θ value	8.99809 (rank : 255)	NC score	-0.000200 (rank : 489)
Query Neighborhood Hits	266	Target Neighborhood Hits	657	Shared Neighborhood Hits	21
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

EP400_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.011341 (rank : 464)
Query Neighborhood Hits	266	Target Neighborhood Hits	556	Shared Neighborhood Hits	52
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ESPL1_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.009775 (rank : 466)
Query Neighborhood Hits	266	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

FOG1_HUMAN
θ value	8.99809 (rank : 258)	NC score	-0.000634 (rank : 490)
Query Neighborhood Hits	266	Target Neighborhood Hits	981	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HXA3_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.005377 (rank : 484)
Query Neighborhood Hits	266	Target Neighborhood Hits	535	Shared Neighborhood Hits	31
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

K2027_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.017160 (rank : 428)
Query Neighborhood Hits	266	Target Neighborhood Hits	194	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

NOTC3_MOUSE
θ value	8.99809 (rank : 261)	NC score	-0.000870 (rank : 491)
Query Neighborhood Hits	266	Target Neighborhood Hits	975	Shared Neighborhood Hits	28
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PITM1_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.011655 (rank : 461)
Query Neighborhood Hits	266	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

POGZ_MOUSE
θ value	8.99809 (rank : 263)	NC score	-0.003964 (rank : 494)
Query Neighborhood Hits	266	Target Neighborhood Hits	765	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

PRRT3_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.070698 (rank : 213)
Query Neighborhood Hits	266	Target Neighborhood Hits	998	Shared Neighborhood Hits	124
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

VPS54_MOUSE
θ value	8.99809 (rank : 265)	NC score	0.006877 (rank : 482)
Query Neighborhood Hits	266	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

ZBT40_HUMAN
θ value	8.99809 (rank : 266)	NC score	-0.005004 (rank : 495)
Query Neighborhood Hits	266	Target Neighborhood Hits	949	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ABI1_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.076993 (rank : 181)
Query Neighborhood Hits	266	Target Neighborhood Hits	257	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.080022 (rank : 167)
Query Neighborhood Hits	266	Target Neighborhood Hits	246	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.088988 (rank : 149)
Query Neighborhood Hits	266	Target Neighborhood Hits	350	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.084313 (rank : 155)
Query Neighborhood Hits	266	Target Neighborhood Hits	266	Shared Neighborhood Hits	26
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.074181 (rank : 194)
Query Neighborhood Hits	266	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.071689 (rank : 208)
Query Neighborhood Hits	266	Target Neighborhood Hits	227	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ADIPO_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.071686 (rank : 209)
Query Neighborhood Hits	266	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

ADIPO_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.074145 (rank : 195)
Query Neighborhood Hits	266	Target Neighborhood Hits	182	Shared Neighborhood Hits	54
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

AHI1_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.062949 (rank : 261)
Query Neighborhood Hits	266	Target Neighborhood Hits	537	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.061301 (rank : 267)
Query Neighborhood Hits	266	Target Neighborhood Hits	496	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ANM2_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.050214 (rank : 346)
Query Neighborhood Hits	266	Target Neighborhood Hits	175	Shared Neighborhood Hits	12
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARHG4_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.440334 (rank : 44)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.463379 (rank : 36)
Query Neighborhood Hits	266	Target Neighborhood Hits	185	Shared Neighborhood Hits	57
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG6_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.253929 (rank : 67)
Query Neighborhood Hits	266	Target Neighborhood Hits	376	Shared Neighborhood Hits	50
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.232553 (rank : 70)
Query Neighborhood Hits	266	Target Neighborhood Hits	394	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.284080 (rank : 62)
Query Neighborhood Hits	266	Target Neighborhood Hits	347	Shared Neighborhood Hits	63
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.261390 (rank : 63)
Query Neighborhood Hits	266	Target Neighborhood Hits	396	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG9_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.457580 (rank : 39)
Query Neighborhood Hits	266	Target Neighborhood Hits	235	Shared Neighborhood Hits	59
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.456708 (rank : 42)
Query Neighborhood Hits	266	Target Neighborhood Hits	234	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

BAIP2_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.056421 (rank : 296)
Query Neighborhood Hits	266	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.057240 (rank : 286)
Query Neighborhood Hits	266	Target Neighborhood Hits	185	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BCAR1_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.058842 (rank : 274)
Query Neighborhood Hits	266	Target Neighborhood Hits	554	Shared Neighborhood Hits	65
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.057196 (rank : 288)
Query Neighborhood Hits	266	Target Neighborhood Hits	438	Shared Neighborhood Hits	50
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BI2L1_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.076149 (rank : 185)
Query Neighborhood Hits	266	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BI2L1_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.066691 (rank : 241)
Query Neighborhood Hits	266	Target Neighborhood Hits	197	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BSN_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.052146 (rank : 321)
Query Neighborhood Hits	266	Target Neighborhood Hits	1537	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.058692 (rank : 276)
Query Neighborhood Hits	266	Target Neighborhood Hits	2057	Shared Neighborhood Hits	156
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

C1QA_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.070318 (rank : 215)
Query Neighborhood Hits	266	Target Neighborhood Hits	179	Shared Neighborhood Hits	49
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

C1QA_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.070126 (rank : 216)
Query Neighborhood Hits	266	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	P98086	Gene names	C1qa
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

C1QB_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.067487 (rank : 235)
Query Neighborhood Hits	266	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	P02746, Q5T959, Q96H17	Gene names	C1QB
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

C1QB_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.068654 (rank : 225)
Query Neighborhood Hits	266	Target Neighborhood Hits	126	Shared Neighborhood Hits	49
SwissProt Accessions	P14106	Gene names	C1qb
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

C1QC_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.065908 (rank : 247)
Query Neighborhood Hits	266	Target Neighborhood Hits	124	Shared Neighborhood Hits	48
SwissProt Accessions	P02747, Q7Z502, Q96DL2, Q96H05	Gene names	C1QC, C1QG
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

C1QC_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.069439 (rank : 218)
Query Neighborhood Hits	266	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

C1QL3_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.057894 (rank : 284)
Query Neighborhood Hits	266	Target Neighborhood Hits	127	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESN4	Gene names	C1ql3, C1ql
Domain Architecture
Description	Complement C1q-like protein 3 precursor (Gliacolin).

C1QRF_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.058347 (rank : 278)
Query Neighborhood Hits	266	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	O75973	Gene names	C1QL1, C1QRF, CRF
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

C1QRF_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.058647 (rank : 277)
Query Neighborhood Hits	266	Target Neighborhood Hits	140	Shared Neighborhood Hits	55
SwissProt Accessions	O88992	Gene names	C1ql1, C1qrf, Crf
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

C1QT1_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.056781 (rank : 293)
Query Neighborhood Hits	266	Target Neighborhood Hits	125	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXJ1, Q96NF2, Q9GZR4	Gene names	C1QTNF1, CTRP1
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 1 precursor (G protein-coupled receptor-interacting protein) (GIP).

C1QT2_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.068014 (rank : 231)
Query Neighborhood Hits	266	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXJ5	Gene names	C1QTNF2, CTRP2
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 2 precursor.

C1QT3_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.056500 (rank : 294)
Query Neighborhood Hits	266	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXJ4, Q6MZN1, Q96KY1	Gene names	C1QTNF3, CTRP3
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 3 precursor (Secretory protein CORS26).

C1QT3_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.057084 (rank : 289)
Query Neighborhood Hits	266	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ES30	Gene names	C1qtnf3, Cors26, Ctrp3
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 3 precursor (Secretory protein CORS26).

C1QT5_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.065318 (rank : 249)
Query Neighborhood Hits	266	Target Neighborhood Hits	137	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BXJ0, Q8N6P2, Q9UFX4	Gene names	C1QTNF5, CTRP5
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

C1QT5_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.062211 (rank : 265)
Query Neighborhood Hits	266	Target Neighborhood Hits	131	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

C1QT6_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.053009 (rank : 311)
Query Neighborhood Hits	266	Target Neighborhood Hits	122	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXI9	Gene names	C1QTNF6, CTRP6
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 6 precursor.

C1QT7_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.066624 (rank : 243)
Query Neighborhood Hits	266	Target Neighborhood Hits	119	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXJ2	Gene names	C1QTNF7, CTRP7
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

C1QT7_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.068441 (rank : 227)
Query Neighborhood Hits	266	Target Neighborhood Hits	124	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BVD7, Q8CHX9	Gene names	C1qtnf7, Ctrp7
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

CASL_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.052063 (rank : 322)
Query Neighborhood Hits	266	Target Neighborhood Hits	259	Shared Neighborhood Hits	26
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CD2AP_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.114356 (rank : 83)
Query Neighborhood Hits	266	Target Neighborhood Hits	315	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.117729 (rank : 78)
Query Neighborhood Hits	266	Target Neighborhood Hits	336	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CGRE1_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.058346 (rank : 279)
Query Neighborhood Hits	266	Target Neighborhood Hits	354	Shared Neighborhood Hits	77
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CO1A2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.096351 (rank : 136)
Query Neighborhood Hits	266	Target Neighborhood Hits	329	Shared Neighborhood Hits	77
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A2_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.097360 (rank : 134)
Query Neighborhood Hits	266	Target Neighborhood Hits	388	Shared Neighborhood Hits	77
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A6_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.105133 (rank : 111)
Query Neighborhood Hits	266	Target Neighborhood Hits	318	Shared Neighborhood Hits	63
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CO6A3_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.066810 (rank : 240)
Query Neighborhood Hits	266	Target Neighborhood Hits	317	Shared Neighborhood Hits	56
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CO9A1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.095543 (rank : 138)
Query Neighborhood Hits	266	Target Neighborhood Hits	420	Shared Neighborhood Hits	81
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A1_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.098338 (rank : 133)
Query Neighborhood Hits	266	Target Neighborhood Hits	477	Shared Neighborhood Hits	84
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A2_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.094879 (rank : 140)
Query Neighborhood Hits	266	Target Neighborhood Hits	261	Shared Neighborhood Hits	64
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO9A3_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.099151 (rank : 132)
Query Neighborhood Hits	266	Target Neighborhood Hits	361	Shared Neighborhood Hits	74
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COAA1_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.090628 (rank : 146)
Query Neighborhood Hits	266	Target Neighborhood Hits	286	Shared Neighborhood Hits	61
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COFA1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.074727 (rank : 192)
Query Neighborhood Hits	266	Target Neighborhood Hits	292	Shared Neighborhood Hits	75
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

COFA1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.076292 (rank : 184)
Query Neighborhood Hits	266	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

COLQ_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.082203 (rank : 160)
Query Neighborhood Hits	266	Target Neighborhood Hits	193	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

CRKL_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.083298 (rank : 158)
Query Neighborhood Hits	266	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.081083 (rank : 164)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.071036 (rank : 212)
Query Neighborhood Hits	266	Target Neighborhood Hits	308	Shared Neighborhood Hits	19
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.073268 (rank : 203)
Query Neighborhood Hits	266	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CT032_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.055176 (rank : 302)
Query Neighborhood Hits	266	Target Neighborhood Hits	235	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CTHR1_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.067453 (rank : 236)
Query Neighborhood Hits	266	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.067336 (rank : 237)
Query Neighborhood Hits	266	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

DBNL_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.065303 (rank : 250)
Query Neighborhood Hits	266	Target Neighborhood Hits	244	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.061057 (rank : 268)
Query Neighborhood Hits	266	Target Neighborhood Hits	306	Shared Neighborhood Hits	21
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DIDO1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.067769 (rank : 233)
Query Neighborhood Hits	266	Target Neighborhood Hits	960	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EDA_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.068849 (rank : 222)
Query Neighborhood Hits	266	Target Neighborhood Hits	134	Shared Neighborhood Hits	59
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EDA_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.068646 (rank : 226)
Query Neighborhood Hits	266	Target Neighborhood Hits	141	Shared Neighborhood Hits	57
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EFS_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.056828 (rank : 292)
Query Neighborhood Hits	266	Target Neighborhood Hits	348	Shared Neighborhood Hits	37
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.060849 (rank : 269)
Query Neighborhood Hits	266	Target Neighborhood Hits	389	Shared Neighborhood Hits	44
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

EHD1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.052335 (rank : 317)
Query Neighborhood Hits	266	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4M9, O14611, Q9UNR3	Gene names	EHD1, PAST, PAST1
Domain Architecture
Description	EH-domain-containing protein 1 (Testilin) (hPAST1).

EHD1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.052246 (rank : 320)
Query Neighborhood Hits	266	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVK4	Gene names	Ehd1, Past1
Domain Architecture
Description	EH-domain-containing protein 1 (mPAST1).

EHD2_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.051753 (rank : 324)
Query Neighborhood Hits	266	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN4, Q96CB6	Gene names	EHD2
Domain Architecture
Description	EH-domain-containing protein 2.

EHD3_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.051616 (rank : 325)
Query Neighborhood Hits	266	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN3, Q8N514, Q9NZB3	Gene names	EHD3, EHD2
Domain Architecture
Description	EH-domain-containing protein 3.

EHD3_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.051258 (rank : 329)
Query Neighborhood Hits	266	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXY6	Gene names	Ehd3, Ehd2
Domain Architecture
Description	EH-domain-containing protein 3.

EHD4_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.051020 (rank : 334)
Query Neighborhood Hits	266	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQP2	Gene names	Ehd4, Past2
Domain Architecture
Description	EH-domain-containing protein 4 (mPAST2).

ELN_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.060496 (rank : 270)
Query Neighborhood Hits	266	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

EMID1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.074073 (rank : 196)
Query Neighborhood Hits	266	Target Neighborhood Hits	215	Shared Neighborhood Hits	62
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EMID2_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.072258 (rank : 206)
Query Neighborhood Hits	266	Target Neighborhood Hits	226	Shared Neighborhood Hits	66
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EMID2_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.067547 (rank : 234)
Query Neighborhood Hits	266	Target Neighborhood Hits	201	Shared Neighborhood Hits	61
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EMIL1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.051282 (rank : 328)
Query Neighborhood Hits	266	Target Neighborhood Hits	239	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EMIL1_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.050280 (rank : 345)
Query Neighborhood Hits	266	Target Neighborhood Hits	214	Shared Neighborhood Hits	57
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EP15R_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.050052 (rank : 349)
Query Neighborhood Hits	266	Target Neighborhood Hits	1083	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.054303 (rank : 304)
Query Neighborhood Hits	266	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.051229 (rank : 332)
Query Neighborhood Hits	266	Target Neighborhood Hits	1021	Shared Neighborhood Hits	34
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.050614 (rank : 338)
Query Neighborhood Hits	266	Target Neighborhood Hits	820	Shared Neighborhood Hits	20
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

FARP1_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.253950 (rank : 66)
Query Neighborhood Hits	266	Target Neighborhood Hits	241	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.257272 (rank : 64)
Query Neighborhood Hits	266	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.286525 (rank : 61)
Query Neighborhood Hits	266	Target Neighborhood Hits	209	Shared Neighborhood Hits	59
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FYV1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.050323 (rank : 344)
Query Neighborhood Hits	266	Target Neighborhood Hits	217	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

GLDN_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.067108 (rank : 238)
Query Neighborhood Hits	266	Target Neighborhood Hits	159	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

GLDN_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.066843 (rank : 239)
Query Neighborhood Hits	266	Target Neighborhood Hits	155	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

GNRP_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.299574 (rank : 60)
Query Neighborhood Hits	266	Target Neighborhood Hits	239	Shared Neighborhood Hits	53
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.306371 (rank : 59)
Query Neighborhood Hits	266	Target Neighborhood Hits	191	Shared Neighborhood Hits	51
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GRAP2_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.069680 (rank : 217)
Query Neighborhood Hits	266	Target Neighborhood Hits	304	Shared Neighborhood Hits	20
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.069026 (rank : 221)
Query Neighborhood Hits	266	Target Neighborhood Hits	297	Shared Neighborhood Hits	19
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.102287 (rank : 123)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.102132 (rank : 124)
Query Neighborhood Hits	266	Target Neighborhood Hits	309	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.088216 (rank : 150)
Query Neighborhood Hits	266	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.088117 (rank : 151)
Query Neighborhood Hits	266	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HCLS1_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.079423 (rank : 171)
Query Neighborhood Hits	266	Target Neighborhood Hits	358	Shared Neighborhood Hits	44
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.077491 (rank : 179)
Query Neighborhood Hits	266	Target Neighborhood Hits	329	Shared Neighborhood Hits	36
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HGS_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.079897 (rank : 169)
Query Neighborhood Hits	266	Target Neighborhood Hits	517	Shared Neighborhood Hits	50
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.079073 (rank : 173)
Query Neighborhood Hits	266	Target Neighborhood Hits	589	Shared Neighborhood Hits	51
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

IASPP_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.075896 (rank : 186)
Query Neighborhood Hits	266	Target Neighborhood Hits	1024	Shared Neighborhood Hits	114
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LASP1_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.066008 (rank : 246)
Query Neighborhood Hits	266	Target Neighborhood Hits	293	Shared Neighborhood Hits	20
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.064251 (rank : 254)
Query Neighborhood Hits	266	Target Neighborhood Hits	297	Shared Neighborhood Hits	21
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LMO7_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.055232 (rank : 301)
Query Neighborhood Hits	266	Target Neighborhood Hits	507	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MARCO_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.073574 (rank : 202)
Query Neighborhood Hits	266	Target Neighborhood Hits	199	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

MIA_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.050410 (rank : 342)
Query Neighborhood Hits	266	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q16674	Gene names	MIA
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity).

MIA_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.050432 (rank : 341)
Query Neighborhood Hits	266	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q61865, O09086, P97495	Gene names	Mia, Cdrap, Mia1
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity) (Cartilage-derived retinoic acid-sensitive protein) (CD-RAP).

MSRE_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.063135 (rank : 257)
Query Neighborhood Hits	266	Target Neighborhood Hits	298	Shared Neighborhood Hits	54
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

MSRE_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.052275 (rank : 318)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	54
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

MTSS1_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.056930 (rank : 290)
Query Neighborhood Hits	266	Target Neighborhood Hits	592	Shared Neighborhood Hits	105
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUC1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.083258 (rank : 159)
Query Neighborhood Hits	266	Target Neighborhood Hits	975	Shared Neighborhood Hits	121
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NACAM_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.050389 (rank : 343)
Query Neighborhood Hits	266	Target Neighborhood Hits	1866	Shared Neighborhood Hits	131
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCF1_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.111153 (rank : 88)
Query Neighborhood Hits	266	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.109740 (rank : 95)
Query Neighborhood Hits	266	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF2_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.109238 (rank : 97)
Query Neighborhood Hits	266	Target Neighborhood Hits	229	Shared Neighborhood Hits	18
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCF4_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.073914 (rank : 201)
Query Neighborhood Hits	266	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.074915 (rank : 191)
Query Neighborhood Hits	266	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK1_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.108285 (rank : 102)
Query Neighborhood Hits	266	Target Neighborhood Hits	312	Shared Neighborhood Hits	23
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.104966 (rank : 112)
Query Neighborhood Hits	266	Target Neighborhood Hits	310	Shared Neighborhood Hits	25
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCOA6_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.053561 (rank : 309)
Query Neighborhood Hits	266	Target Neighborhood Hits	1202	Shared Neighborhood Hits	117
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NEBL_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.059905 (rank : 272)
Query Neighborhood Hits	266	Target Neighborhood Hits	457	Shared Neighborhood Hits	27
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NOXO1_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.062399 (rank : 264)
Query Neighborhood Hits	266	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.074028 (rank : 198)
Query Neighborhood Hits	266	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.057903 (rank : 283)
Query Neighborhood Hits	266	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.054098 (rank : 305)
Query Neighborhood Hits	266	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

OSTF1_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.059687 (rank : 273)
Query Neighborhood Hits	266	Target Neighborhood Hits	466	Shared Neighborhood Hits	20
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.058727 (rank : 275)
Query Neighborhood Hits	266	Target Neighborhood Hits	467	Shared Neighborhood Hits	20
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

P85A_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.052819 (rank : 312)
Query Neighborhood Hits	266	Target Neighborhood Hits	479	Shared Neighborhood Hits	24
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.050182 (rank : 347)
Query Neighborhood Hits	266	Target Neighborhood Hits	435	Shared Neighborhood Hits	22
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.051493 (rank : 326)
Query Neighborhood Hits	266	Target Neighborhood Hits	543	Shared Neighborhood Hits	34
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PACN1_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.051323 (rank : 327)
Query Neighborhood Hits	266	Target Neighborhood Hits	320	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.051244 (rank : 330)
Query Neighborhood Hits	266	Target Neighborhood Hits	283	Shared Neighborhood Hits	18
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN2_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.052639 (rank : 313)
Query Neighborhood Hits	266	Target Neighborhood Hits	339	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.053493 (rank : 310)
Query Neighborhood Hits	266	Target Neighborhood Hits	382	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.058187 (rank : 282)
Query Neighborhood Hits	266	Target Neighborhood Hits	385	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.058201 (rank : 281)
Query Neighborhood Hits	266	Target Neighborhood Hits	380	Shared Neighborhood Hits	24
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PDZD1_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.056426 (rank : 295)
Query Neighborhood Hits	266	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD2_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.050038 (rank : 350)
Query Neighborhood Hits	266	Target Neighborhood Hits	772	Shared Neighborhood Hits	72
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PDZD3_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.057223 (rank : 287)
Query Neighborhood Hits	266	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD3_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.051240 (rank : 331)
Query Neighborhood Hits	266	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PDZD8_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.050447 (rank : 340)
Query Neighborhood Hits	266	Target Neighborhood Hits	185	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PEX13_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.052637 (rank : 314)
Query Neighborhood Hits	266	Target Neighborhood Hits	128	Shared Neighborhood Hits	15
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.052270 (rank : 319)
Query Neighborhood Hits	266	Target Neighborhood Hits	126	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PKHA6_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.051785 (rank : 323)
Query Neighborhood Hits	266	Target Neighborhood Hits	556	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHF1_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.117903 (rank : 77)
Query Neighborhood Hits	266	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.117378 (rank : 79)
Query Neighborhood Hits	266	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.124044 (rank : 73)
Query Neighborhood Hits	266	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.123464 (rank : 74)
Query Neighborhood Hits	266	Target Neighborhood Hits	77	Shared Neighborhood Hits	15
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHG4_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.244966 (rank : 68)
Query Neighborhood Hits	266	Target Neighborhood Hits	200	Shared Neighborhood Hits	91
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PLCG1_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.078664 (rank : 175)
Query Neighborhood Hits	266	Target Neighborhood Hits	293	Shared Neighborhood Hits	18
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.080900 (rank : 166)
Query Neighborhood Hits	266	Target Neighborhood Hits	314	Shared Neighborhood Hits	18
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.068398 (rank : 229)
Query Neighborhood Hits	266	Target Neighborhood Hits	280	Shared Neighborhood Hits	15
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PPIP1_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.078456 (rank : 177)
Query Neighborhood Hits	266	Target Neighborhood Hits	389	Shared Neighborhood Hits	24
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PPIP1_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.075419 (rank : 188)
Query Neighborhood Hits	266	Target Neighborhood Hits	377	Shared Neighborhood Hits	26
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

RBNS5_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.076944 (rank : 182)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.069059 (rank : 220)
Query Neighborhood Hits	266	Target Neighborhood Hits	266	Shared Neighborhood Hits	24
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

REPS1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.066446 (rank : 245)
Query Neighborhood Hits	266	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REPS1_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.069120 (rank : 219)
Query Neighborhood Hits	266	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REPS2_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.078553 (rank : 176)
Query Neighborhood Hits	266	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

REPS2_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.077304 (rank : 180)
Query Neighborhood Hits	266	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

RGS3_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.085362 (rank : 153)
Query Neighborhood Hits	266	Target Neighborhood Hits	1621	Shared Neighborhood Hits	157
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHG04_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.052600 (rank : 315)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHPN1_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.063347 (rank : 255)
Query Neighborhood Hits	266	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.067841 (rank : 232)
Query Neighborhood Hits	266	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RIMB1_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.050599 (rank : 339)
Query Neighborhood Hits	266	Target Neighborhood Hits	1479	Shared Neighborhood Hits	110
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.055679 (rank : 298)
Query Neighborhood Hits	266	Target Neighborhood Hits	263	Shared Neighborhood Hits	25
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.055367 (rank : 300)
Query Neighborhood Hits	266	Target Neighborhood Hits	246	Shared Neighborhood Hits	20
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RPTN_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.068030 (rank : 230)
Query Neighborhood Hits	266	Target Neighborhood Hits	650	Shared Neighborhood Hits	75
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RUFY1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.051150 (rank : 333)
Query Neighborhood Hits	266	Target Neighborhood Hits	848	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.050845 (rank : 336)
Query Neighborhood Hits	266	Target Neighborhood Hits	765	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.052495 (rank : 316)
Query Neighborhood Hits	266	Target Neighborhood Hits	1208	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.053894 (rank : 306)
Query Neighborhood Hits	266	Target Neighborhood Hits	820	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SCAR3_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.078088 (rank : 178)
Query Neighborhood Hits	266	Target Neighborhood Hits	205	Shared Neighborhood Hits	63
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

SCAR3_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.075314 (rank : 189)
Query Neighborhood Hits	266	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

SFTPA_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.056849 (rank : 291)
Query Neighborhood Hits	266	Target Neighborhood Hits	169	Shared Neighborhood Hits	48
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

SFTPD_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.068807 (rank : 223)
Query Neighborhood Hits	266	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	P35247, Q86YK9, Q9UCJ2, Q9UCJ3	Gene names	SFTPD, PSPD, SFTP4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SFTPD_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.065100 (rank : 252)
Query Neighborhood Hits	266	Target Neighborhood Hits	217	Shared Neighborhood Hits	55
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SH3G1_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.064668 (rank : 253)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.062759 (rank : 263)
Query Neighborhood Hits	266	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.062948 (rank : 262)
Query Neighborhood Hits	266	Target Neighborhood Hits	324	Shared Neighborhood Hits	19
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G2_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.062087 (rank : 266)
Query Neighborhood Hits	266	Target Neighborhood Hits	319	Shared Neighborhood Hits	19
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G3_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.066658 (rank : 242)
Query Neighborhood Hits	266	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G3_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.068426 (rank : 228)
Query Neighborhood Hits	266	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3K1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.121622 (rank : 76)
Query Neighborhood Hits	266	Target Neighborhood Hits	341	Shared Neighborhood Hits	27
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.109333 (rank : 96)
Query Neighborhood Hits	266	Target Neighborhood Hits	332	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SHAN1_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.085171 (rank : 154)
Query Neighborhood Hits	266	Target Neighborhood Hits	1041	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.063202 (rank : 256)
Query Neighborhood Hits	266	Target Neighborhood Hits	346	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.108495 (rank : 101)
Query Neighborhood Hits	266	Target Neighborhood Hits	446	Shared Neighborhood Hits	40
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SON_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.073981 (rank : 199)
Query Neighborhood Hits	266	Target Neighborhood Hits	1568	Shared Neighborhood Hits	144
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.053818 (rank : 307)
Query Neighborhood Hits	266	Target Neighborhood Hits	957	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SOS1_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.110738 (rank : 90)
Query Neighborhood Hits	266	Target Neighborhood Hits	274	Shared Neighborhood Hits	40
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.099802 (rank : 130)
Query Neighborhood Hits	266	Target Neighborhood Hits	281	Shared Neighborhood Hits	36
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS2_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.102634 (rank : 122)
Query Neighborhood Hits	266	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SRBS1_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.116402 (rank : 81)
Query Neighborhood Hits	266	Target Neighborhood Hits	396	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.122468 (rank : 75)
Query Neighborhood Hits	266	Target Neighborhood Hits	409	Shared Neighborhood Hits	31
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.074445 (rank : 193)
Query Neighborhood Hits	266	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.073927 (rank : 200)
Query Neighborhood Hits	266	Target Neighborhood Hits	292	Shared Neighborhood Hits	21
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SSBP4_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.063012 (rank : 260)
Query Neighborhood Hits	266	Target Neighborhood Hits	753	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STAC3_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.071539 (rank : 210)
Query Neighborhood Hits	266	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.072119 (rank : 207)
Query Neighborhood Hits	266	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.081370 (rank : 162)
Query Neighborhood Hits	266	Target Neighborhood Hits	276	Shared Neighborhood Hits	23
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.079866 (rank : 170)
Query Neighborhood Hits	266	Target Neighborhood Hits	268	Shared Neighborhood Hits	23
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.075285 (rank : 190)
Query Neighborhood Hits	266	Target Neighborhood Hits	271	Shared Neighborhood Hits	22
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.075556 (rank : 187)
Query Neighborhood Hits	266	Target Neighborhood Hits	273	Shared Neighborhood Hits	23
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.070548 (rank : 214)
Query Neighborhood Hits	266	Target Neighborhood Hits	288	Shared Neighborhood Hits	22
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.071399 (rank : 211)
Query Neighborhood Hits	266	Target Neighborhood Hits	285	Shared Neighborhood Hits	21
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TCGAP_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.068797 (rank : 224)
Query Neighborhood Hits	266	Target Neighborhood Hits	872	Shared Neighborhood Hits	107
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

UN13A_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.054998 (rank : 303)
Query Neighborhood Hits	266	Target Neighborhood Hits	285	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

USH1C_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.050068 (rank : 348)
Query Neighborhood Hits	266	Target Neighborhood Hits	327	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

VINEX_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.110797 (rank : 89)
Query Neighborhood Hits	266	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.109122 (rank : 99)
Query Neighborhood Hits	266	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ZFY16_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.081413 (rank : 161)
Query Neighborhood Hits	266	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.083681 (rank : 156)
Query Neighborhood Hits	266	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFY19_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.056370 (rank : 297)
Query Neighborhood Hits	266	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.053601 (rank : 308)
Query Neighborhood Hits	266	Target Neighborhood Hits	143	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY21_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.079375 (rank : 172)
Query Neighborhood Hits	266	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.081103 (rank : 163)
Query Neighborhood Hits	266	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.095477 (rank : 139)
Query Neighborhood Hits	266	Target Neighborhood Hits	152	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFYV1_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.050631 (rank : 337)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV9_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.087898 (rank : 152)
Query Neighborhood Hits	266	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

Hits sorted by NC score

ARHG1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	266	Target Neighborhood Hits	266	Shared Neighborhood Hits	266
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG1_HUMAN
NC score	0.969890 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	266	Target Neighborhood Hits	176	Shared Neighborhood Hits	119
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHGC_MOUSE
NC score	0.845988 (rank : 3)	θ value	8.91014e-149 (rank : 3)
Query Neighborhood Hits	266	Target Neighborhood Hits	344	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LBC_HUMAN
NC score	0.842877 (rank : 4)	θ value	7.03111e-45 (rank : 6)
Query Neighborhood Hits	266	Target Neighborhood Hits	90	Shared Neighborhood Hits	52
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

ARHGC_HUMAN
NC score	0.842185 (rank : 5)	θ value	1.28662e-147 (rank : 4)
Query Neighborhood Hits	266	Target Neighborhood Hits	351	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGB_HUMAN
NC score	0.813101 (rank : 6)	θ value	1.06975e-93 (rank : 5)
Query Neighborhood Hits	266	Target Neighborhood Hits	375	Shared Neighborhood Hits	78
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHG2_MOUSE
NC score	0.808646 (rank : 7)	θ value	2.67802e-36 (rank : 7)
Query Neighborhood Hits	266	Target Neighborhood Hits	120	Shared Neighborhood Hits	53
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG2_HUMAN
NC score	0.800198 (rank : 8)	θ value	6.59618e-35 (rank : 8)
Query Neighborhood Hits	266	Target Neighborhood Hits	142	Shared Neighborhood Hits	54
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG3_MOUSE
NC score	0.683059 (rank : 9)	θ value	3.07829e-16 (rank : 14)
Query Neighborhood Hits	266	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG3_HUMAN
NC score	0.682843 (rank : 10)	θ value	1.16975e-15 (rank : 16)
Query Neighborhood Hits	266	Target Neighborhood Hits	82	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

RGNEF_MOUSE
NC score	0.676855 (rank : 11)	θ value	7.54701e-31 (rank : 9)
Query Neighborhood Hits	266	Target Neighborhood Hits	641	Shared Neighborhood Hits	70
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ARHG8_HUMAN
NC score	0.666952 (rank : 12)	θ value	9.90251e-15 (rank : 19)
Query Neighborhood Hits	266	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHGG_HUMAN
NC score	0.658485 (rank : 13)	θ value	4.59992e-12 (rank : 28)
Query Neighborhood Hits	266	Target Neighborhood Hits	129	Shared Neighborhood Hits	58
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ECT2_MOUSE
NC score	0.658344 (rank : 14)	θ value	8.95645e-16 (rank : 15)
Query Neighborhood Hits	266	Target Neighborhood Hits	98	Shared Neighborhood Hits	58
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ARHG8_MOUSE
NC score	0.650254 (rank : 15)	θ value	2.88119e-14 (rank : 21)
Query Neighborhood Hits	266	Target Neighborhood Hits	79	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGG_MOUSE
NC score	0.648908 (rank : 16)	θ value	2.69671e-12 (rank : 27)
Query Neighborhood Hits	266	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHG5_HUMAN
NC score	0.647010 (rank : 17)	θ value	3.18553e-13 (rank : 24)
Query Neighborhood Hits	266	Target Neighborhood Hits	172	Shared Neighborhood Hits	58
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ECT2_HUMAN
NC score	0.642221 (rank : 18)	θ value	9.90251e-15 (rank : 20)
Query Neighborhood Hits	266	Target Neighborhood Hits	98	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

NGEF_HUMAN
NC score	0.641787 (rank : 19)	θ value	1.86753e-13 (rank : 23)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
NC score	0.630160 (rank : 20)	θ value	1.2105e-12 (rank : 26)
Query Neighborhood Hits	266	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHGF_HUMAN
NC score	0.619087 (rank : 21)	θ value	1.02475e-11 (rank : 32)
Query Neighborhood Hits	266	Target Neighborhood Hits	214	Shared Neighborhood Hits	75
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

FGD3_MOUSE
NC score	0.564919 (rank : 22)	θ value	1.42992e-13 (rank : 22)
Query Neighborhood Hits	266	Target Neighborhood Hits	257	Shared Neighborhood Hits	68
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD3_HUMAN
NC score	0.545154 (rank : 23)	θ value	2.13673e-09 (rank : 39)
Query Neighborhood Hits	266	Target Neighborhood Hits	249	Shared Neighborhood Hits	81
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD4_HUMAN
NC score	0.541446 (rank : 24)	θ value	1.99529e-15 (rank : 18)
Query Neighborhood Hits	266	Target Neighborhood Hits	219	Shared Neighborhood Hits	58
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
NC score	0.541340 (rank : 25)	θ value	1.16975e-15 (rank : 17)
Query Neighborhood Hits	266	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD2_MOUSE
NC score	0.535221 (rank : 26)	θ value	1.133e-10 (rank : 34)
Query Neighborhood Hits	266	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

TIAM1_MOUSE
NC score	0.533093 (rank : 27)	θ value	3.64472e-09 (rank : 41)
Query Neighborhood Hits	266	Target Neighborhood Hits	205	Shared Neighborhood Hits	58
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

FGD2_HUMAN
NC score	0.530007 (rank : 28)	θ value	2.98157e-11 (rank : 33)
Query Neighborhood Hits	266	Target Neighborhood Hits	151	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

PREX1_HUMAN
NC score	0.527458 (rank : 29)	θ value	8.97725e-08 (rank : 44)
Query Neighborhood Hits	266	Target Neighborhood Hits	177	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

TIAM1_HUMAN
NC score	0.525720 (rank : 30)	θ value	1.25267e-09 (rank : 37)
Query Neighborhood Hits	266	Target Neighborhood Hits	225	Shared Neighborhood Hits	61
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

FGD1_MOUSE
NC score	0.521609 (rank : 31)	θ value	2.13673e-09 (rank : 38)
Query Neighborhood Hits	266	Target Neighborhood Hits	387	Shared Neighborhood Hits	110
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_HUMAN
NC score	0.514783 (rank : 32)	θ value	1.38499e-08 (rank : 43)
Query Neighborhood Hits	266	Target Neighborhood Hits	367	Shared Neighborhood Hits	95
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PKHG1_HUMAN
NC score	0.497172 (rank : 33)	θ value	1.99992e-07 (rank : 45)
Query Neighborhood Hits	266	Target Neighborhood Hits	174	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ARHGA_HUMAN
NC score	0.492686 (rank : 34)	θ value	2.79066e-09 (rank : 40)
Query Neighborhood Hits	266	Target Neighborhood Hits	187	Shared Neighborhood Hits	58
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ITSN2_HUMAN
NC score	0.463689 (rank : 35)	θ value	3.62785e-25 (rank : 10)
Query Neighborhood Hits	266	Target Neighborhood Hits	1173	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ARHG4_MOUSE
NC score	0.463379 (rank : 36)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	266	Target Neighborhood Hits	185	Shared Neighborhood Hits	57
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

VAV_MOUSE
NC score	0.462497 (rank : 37)	θ value	9.26847e-13 (rank : 25)
Query Neighborhood Hits	266	Target Neighborhood Hits	430	Shared Neighborhood Hits	62
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ARHGA_MOUSE
NC score	0.459931 (rank : 38)	θ value	1.06045e-08 (rank : 42)
Query Neighborhood Hits	266	Target Neighborhood Hits	125	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHG9_HUMAN
NC score	0.457580 (rank : 39)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	266	Target Neighborhood Hits	235	Shared Neighborhood Hits	59
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

VAV2_MOUSE
NC score	0.457294 (rank : 40)	θ value	5.62301e-10 (rank : 36)
Query Neighborhood Hits	266	Target Neighborhood Hits	456	Shared Neighborhood Hits	71
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV2_HUMAN
NC score	0.456893 (rank : 41)	θ value	5.62301e-10 (rank : 35)
Query Neighborhood Hits	266	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ARHG9_MOUSE
NC score	0.456708 (rank : 42)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	266	Target Neighborhood Hits	234	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

VAV_HUMAN
NC score	0.445741 (rank : 43)	θ value	7.84624e-12 (rank : 31)
Query Neighborhood Hits	266	Target Neighborhood Hits	452	Shared Neighborhood Hits	62
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ARHG4_HUMAN
NC score	0.440334 (rank : 44)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ITSN2_MOUSE
NC score	0.439738 (rank : 45)	θ value	6.84181e-24 (rank : 12)
Query Neighborhood Hits	266	Target Neighborhood Hits	1371	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

FGD6_MOUSE
NC score	0.438391 (rank : 46)	θ value	7.59969e-07 (rank : 46)
Query Neighborhood Hits	266	Target Neighborhood Hits	282	Shared Neighborhood Hits	59
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

VAV3_HUMAN
NC score	0.435652 (rank : 47)	θ value	6.00763e-12 (rank : 30)
Query Neighborhood Hits	266	Target Neighborhood Hits	398	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
NC score	0.435345 (rank : 48)	θ value	4.59992e-12 (rank : 29)
Query Neighborhood Hits	266	Target Neighborhood Hits	404	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

FGD6_HUMAN
NC score	0.435148 (rank : 49)	θ value	1.69304e-06 (rank : 47)
Query Neighborhood Hits	266	Target Neighborhood Hits	237	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

MCF2_HUMAN
NC score	0.434182 (rank : 50)	θ value	4.1701e-05 (rank : 48)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	58
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

ITSN1_HUMAN
NC score	0.425773 (rank : 51)	θ value	5.23862e-24 (rank : 11)
Query Neighborhood Hits	266	Target Neighborhood Hits	1757	Shared Neighborhood Hits	109
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.424776 (rank : 52)	θ value	3.39556e-23 (rank : 13)
Query Neighborhood Hits	266	Target Neighborhood Hits	1669	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MCF2L_MOUSE
NC score	0.399912 (rank : 53)	θ value	0.0961366 (rank : 79)
Query Neighborhood Hits	266	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

DNMBP_MOUSE
NC score	0.392524 (rank : 54)	θ value	0.00298849 (rank : 52)
Query Neighborhood Hits	266	Target Neighborhood Hits	435	Shared Neighborhood Hits	69
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_HUMAN
NC score	0.385555 (rank : 55)	θ value	0.000121331 (rank : 49)
Query Neighborhood Hits	266	Target Neighborhood Hits	413	Shared Neighborhood Hits	69
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FGD5_HUMAN
NC score	0.330456 (rank : 56)	θ value	0.00390308 (rank : 53)
Query Neighborhood Hits	266	Target Neighborhood Hits	235	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

HAPIP_HUMAN
NC score	0.325337 (rank : 57)	θ value	0.0113563 (rank : 57)
Query Neighborhood Hits	266	Target Neighborhood Hits	350	Shared Neighborhood Hits	61
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

FGD5_MOUSE
NC score	0.312525 (rank : 58)	θ value	0.00665767 (rank : 56)
Query Neighborhood Hits	266	Target Neighborhood Hits	170	Shared Neighborhood Hits	43
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

GNRP_MOUSE
NC score	0.306371 (rank : 59)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	266	Target Neighborhood Hits	191	Shared Neighborhood Hits	51
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GNRP_HUMAN
NC score	0.299574 (rank : 60)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	266	Target Neighborhood Hits	239	Shared Neighborhood Hits	53
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

FARP2_MOUSE
NC score	0.286525 (rank : 61)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	266	Target Neighborhood Hits	209	Shared Neighborhood Hits	59
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

ARHG7_HUMAN
NC score	0.284080 (rank : 62)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	266	Target Neighborhood Hits	347	Shared Neighborhood Hits	63
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
NC score	0.261390 (rank : 63)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	266	Target Neighborhood Hits	396	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

FARP2_HUMAN
NC score	0.257272 (rank : 64)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	266	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

BCR_HUMAN
NC score	0.253980 (rank : 65)	θ value	0.125558 (rank : 81)
Query Neighborhood Hits	266	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

FARP1_HUMAN
NC score	0.253950 (rank : 66)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	266	Target Neighborhood Hits	241	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

ARHG6_HUMAN
NC score	0.253929 (rank : 67)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	266	Target Neighborhood Hits	376	Shared Neighborhood Hits	50
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

PKHG4_HUMAN
NC score	0.244966 (rank : 68)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	266	Target Neighborhood Hits	200	Shared Neighborhood Hits	91
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

ABR_HUMAN
NC score	0.243670 (rank : 69)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	54
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ARHG6_MOUSE
NC score	0.232553 (rank : 70)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	266	Target Neighborhood Hits	394	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

DUET_HUMAN
NC score	0.150416 (rank : 71)	θ value	0.00509761 (rank : 54)
Query Neighborhood Hits	266	Target Neighborhood Hits	1220	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

TRIO_HUMAN
NC score	0.139827 (rank : 72)	θ value	0.0148317 (rank : 58)
Query Neighborhood Hits	266	Target Neighborhood Hits	1580	Shared Neighborhood Hits	93
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

PKHF2_HUMAN
NC score	0.124044 (rank : 73)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	266	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
NC score	0.123464 (rank : 74)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	266	Target Neighborhood Hits	77	Shared Neighborhood Hits	15
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

SRBS1_MOUSE
NC score	0.122468 (rank : 75)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	266	Target Neighborhood Hits	409	Shared Neighborhood Hits	31
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SH3K1_HUMAN
NC score	0.121622 (rank : 76)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	266	Target Neighborhood Hits	341	Shared Neighborhood Hits	27
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

PKHF1_HUMAN
NC score	0.117903 (rank : 77)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	266	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

CD2AP_MOUSE
NC score	0.117729 (rank : 78)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	266	Target Neighborhood Hits	336	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

PKHF1_MOUSE
NC score	0.117378 (rank : 79)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	266	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

CO5A1_MOUSE
NC score	0.116565 (rank : 80)	θ value	0.0252991 (rank : 63)
Query Neighborhood Hits	266	Target Neighborhood Hits	419	Shared Neighborhood Hits	84
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

SRBS1_HUMAN
NC score	0.116402 (rank : 81)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	266	Target Neighborhood Hits	396	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CO5A1_HUMAN
NC score	0.114421 (rank : 82)	θ value	0.0330416 (rank : 65)
Query Neighborhood Hits	266	Target Neighborhood Hits	434	Shared Neighborhood Hits	87
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CD2AP_HUMAN
NC score	0.114356 (rank : 83)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	266	Target Neighborhood Hits	315	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

COBA1_HUMAN
NC score	0.112261 (rank : 84)	θ value	0.0193708 (rank : 60)
Query Neighborhood Hits	266	Target Neighborhood Hits	491	Shared Neighborhood Hits	84
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO4A2_HUMAN
NC score	0.111863 (rank : 85)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	266	Target Neighborhood Hits	454	Shared Neighborhood Hits	86
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COBA1_MOUSE
NC score	0.111590 (rank : 86)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	266	Target Neighborhood Hits	487	Shared Neighborhood Hits	85
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CONA1_MOUSE
NC score	0.111469 (rank : 87)	θ value	0.365318 (rank : 91)
Query Neighborhood Hits	266	Target Neighborhood Hits	254	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

NCF1_HUMAN
NC score	0.111153 (rank : 88)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	266	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

VINEX_HUMAN
NC score	0.110797 (rank : 89)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	266	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

SOS1_HUMAN
NC score	0.110738 (rank : 90)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	266	Target Neighborhood Hits	274	Shared Neighborhood Hits	40
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

COBA2_HUMAN
NC score	0.110565 (rank : 91)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	266	Target Neighborhood Hits	408	Shared Neighborhood Hits	77
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CO4A5_HUMAN
NC score	0.110514 (rank : 92)	θ value	0.0563607 (rank : 73)
Query Neighborhood Hits	266	Target Neighborhood Hits	383	Shared Neighborhood Hits	88
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO4A2_MOUSE
NC score	0.110094 (rank : 93)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	266	Target Neighborhood Hits	492	Shared Neighborhood Hits	89
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A1_MOUSE
NC score	0.110067 (rank : 94)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	266	Target Neighborhood Hits	450	Shared Neighborhood Hits	87
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

NCF1_MOUSE
NC score	0.109740 (rank : 95)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	266	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

SH3K1_MOUSE
NC score	0.109333 (rank : 96)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	266	Target Neighborhood Hits	332	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

NCF2_HUMAN
NC score	0.109238 (rank : 97)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	266	Target Neighborhood Hits	229	Shared Neighborhood Hits	18
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

CO4A1_HUMAN
NC score	0.109141 (rank : 98)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	266	Target Neighborhood Hits	425	Shared Neighborhood Hits	84
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

VINEX_MOUSE
NC score	0.109122 (rank : 99)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	266	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

COBA2_MOUSE
NC score	0.108895 (rank : 100)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	266	Target Neighborhood Hits	501	Shared Neighborhood Hits	84
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

SHAN2_MOUSE
NC score	0.108495 (rank : 101)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	266	Target Neighborhood Hits	446	Shared Neighborhood Hits	40
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

NCK1_HUMAN
NC score	0.108285 (rank : 102)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	266	Target Neighborhood Hits	312	Shared Neighborhood Hits	23
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

CO8A1_HUMAN
NC score	0.108258 (rank : 103)	θ value	0.0431538 (rank : 71)
Query Neighborhood Hits	266	Target Neighborhood Hits	288	Shared Neighborhood Hits	71
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

CO5A3_HUMAN
NC score	0.108091 (rank : 104)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	266	Target Neighborhood Hits	433	Shared Neighborhood Hits	84
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO8A2_HUMAN
NC score	0.107912 (rank : 105)	θ value	0.00665767 (rank : 55)
Query Neighborhood Hits	266	Target Neighborhood Hits	299	Shared Neighborhood Hits	75
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CONA1_HUMAN
NC score	0.107526 (rank : 106)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	266	Target Neighborhood Hits	281	Shared Neighborhood Hits	71
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

OGFR_MOUSE
NC score	0.107348 (rank : 107)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	266	Target Neighborhood Hits	584	Shared Neighborhood Hits	99
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

CO8A1_MOUSE
NC score	0.105482 (rank : 108)	θ value	0.0736092 (rank : 75)
Query Neighborhood Hits	266	Target Neighborhood Hits	251	Shared Neighborhood Hits	68
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

CO4A3_HUMAN
NC score	0.105408 (rank : 109)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	266	Target Neighborhood Hits	421	Shared Neighborhood Hits	77
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO1A1_HUMAN
NC score	0.105391 (rank : 110)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	266	Target Neighborhood Hits	475	Shared Neighborhood Hits	87
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO4A6_HUMAN
NC score	0.105133 (rank : 111)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	266	Target Neighborhood Hits	318	Shared Neighborhood Hits	63
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

NCK2_HUMAN
NC score	0.104966 (rank : 112)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	266	Target Neighborhood Hits	310	Shared Neighborhood Hits	25
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CO5A2_HUMAN
NC score	0.104898 (rank : 113)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	266	Target Neighborhood Hits	760	Shared Neighborhood Hits	102
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO6A2_MOUSE
NC score	0.104641 (rank : 114)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	266	Target Neighborhood Hits	260	Shared Neighborhood Hits	66
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO3A1_MOUSE
NC score	0.104265 (rank : 115)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	266	Target Neighborhood Hits	466	Shared Neighborhood Hits	83
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COGA1_HUMAN
NC score	0.103930 (rank : 116)	θ value	0.0330416 (rank : 66)
Query Neighborhood Hits	266	Target Neighborhood Hits	345	Shared Neighborhood Hits	74
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CO1A1_MOUSE
NC score	0.103607 (rank : 117)	θ value	0.163984 (rank : 84)
Query Neighborhood Hits	266	Target Neighborhood Hits	457	Shared Neighborhood Hits	85
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
NC score	0.103596 (rank : 118)	θ value	0.163984 (rank : 85)
Query Neighborhood Hits	266	Target Neighborhood Hits	452	Shared Neighborhood Hits	87
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO2A1_HUMAN
NC score	0.103311 (rank : 119)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	266	Target Neighborhood Hits	486	Shared Neighborhood Hits	83
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A4_HUMAN
NC score	0.102872 (rank : 120)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	266	Target Neighborhood Hits	440	Shared Neighborhood Hits	80
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO6A2_HUMAN
NC score	0.102698 (rank : 121)	θ value	1.38821 (rank : 133)
Query Neighborhood Hits	266	Target Neighborhood Hits	249	Shared Neighborhood Hits	63
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

SOS2_HUMAN
NC score	0.102634 (rank : 122)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	266	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

GRAP_HUMAN
NC score	0.102287 (rank : 123)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
NC score	0.102132 (rank : 124)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	266	Target Neighborhood Hits	309	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

COHA1_MOUSE
NC score	0.102039 (rank : 125)	θ value	0.0961366 (rank : 77)
Query Neighborhood Hits	266	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COJA1_HUMAN
NC score	0.101699 (rank : 126)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	266	Target Neighborhood Hits	323	Shared Neighborhood Hits	68
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

COHA1_HUMAN
NC score	0.101363 (rank : 127)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	266	Target Neighborhood Hits	400	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CO9A2_MOUSE
NC score	0.100763 (rank : 128)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	266	Target Neighborhood Hits	279	Shared Neighborhood Hits	68
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO8A2_MOUSE
NC score	0.100596 (rank : 129)	θ value	0.125558 (rank : 82)
Query Neighborhood Hits	266	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

SOS1_MOUSE
NC score	0.099802 (rank : 130)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	266	Target Neighborhood Hits	281	Shared Neighborhood Hits	36
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

CO2A1_MOUSE
NC score	0.099759 (rank : 131)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	266	Target Neighborhood Hits	483	Shared Neighborhood Hits	81
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO9A3_HUMAN
NC score	0.099151 (rank : 132)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	266	Target Neighborhood Hits	361	Shared Neighborhood Hits	74
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CO9A1_MOUSE
NC score	0.098338 (rank : 133)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	266	Target Neighborhood Hits	477	Shared Neighborhood Hits	84
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO1A2_MOUSE
NC score	0.097360 (rank : 134)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	266	Target Neighborhood Hits	388	Shared Neighborhood Hits	77
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO6A1_HUMAN
NC score	0.097276 (rank : 135)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	266	Target Neighborhood Hits	264	Shared Neighborhood Hits	64
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO1A2_HUMAN
NC score	0.096351 (rank : 136)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	266	Target Neighborhood Hits	329	Shared Neighborhood Hits	77
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

OGFR_HUMAN
NC score	0.095681 (rank : 137)	θ value	0.279714 (rank : 90)
Query Neighborhood Hits	266	Target Neighborhood Hits	1582	Shared Neighborhood Hits	158
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CO9A1_HUMAN
NC score	0.095543 (rank : 138)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	266	Target Neighborhood Hits	420	Shared Neighborhood Hits	81
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ZFY28_HUMAN
NC score	0.095477 (rank : 139)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	266	Target Neighborhood Hits	152	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

CO9A2_HUMAN
NC score	0.094879 (rank : 140)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	266	Target Neighborhood Hits	261	Shared Neighborhood Hits	64
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COAA1_HUMAN
NC score	0.093995 (rank : 141)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	266	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CO7A1_HUMAN
NC score	0.093587 (rank : 142)	θ value	0.0193708 (rank : 59)
Query Neighborhood Hits	266	Target Neighborhood Hits	807	Shared Neighborhood Hits	91
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO6A1_MOUSE
NC score	0.093206 (rank : 143)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	266	Target Neighborhood Hits	241	Shared Neighborhood Hits	56
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

BCL9_MOUSE
NC score	0.091511 (rank : 144)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	266	Target Neighborhood Hits	770	Shared Neighborhood Hits	111
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

COIA1_MOUSE
NC score	0.091098 (rank : 145)	θ value	1.38821 (rank : 135)
Query Neighborhood Hits	266	Target Neighborhood Hits	481	Shared Neighborhood Hits	83
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COAA1_MOUSE
NC score	0.090628 (rank : 146)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	266	Target Neighborhood Hits	286	Shared Neighborhood Hits	61
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COIA1_HUMAN
NC score	0.089644 (rank : 147)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	266	Target Neighborhood Hits	447	Shared Neighborhood Hits	83
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

MARCO_MOUSE
NC score	0.089229 (rank : 148)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

ABI2_HUMAN
NC score	0.088988 (rank : 149)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	266	Target Neighborhood Hits	350	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

GRB2_HUMAN
NC score	0.088216 (rank : 150)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	266	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.088117 (rank : 151)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	266	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

ZFYV9_HUMAN
NC score	0.087898 (rank : 152)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	266	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

RGS3_MOUSE
NC score	0.085362 (rank : 153)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	266	Target Neighborhood Hits	1621	Shared Neighborhood Hits	157
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SHAN1_HUMAN
NC score	0.085171 (rank : 154)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	266	Target Neighborhood Hits	1041	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ABI2_MOUSE
NC score	0.084313 (rank : 155)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	266	Target Neighborhood Hits	266	Shared Neighborhood Hits	26
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ZFY16_MOUSE
NC score	0.083681 (rank : 156)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	266	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

EMID1_MOUSE
NC score	0.083498 (rank : 157)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	266	Target Neighborhood Hits	230	Shared Neighborhood Hits	61
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

CRKL_HUMAN
NC score	0.083298 (rank : 158)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	266	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

MUC1_HUMAN
NC score	0.083258 (rank : 159)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	266	Target Neighborhood Hits	975	Shared Neighborhood Hits	121
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

COLQ_HUMAN
NC score	0.082203 (rank : 160)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	266	Target Neighborhood Hits	193	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

ZFY16_HUMAN
NC score	0.081413 (rank : 161)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	266	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

STAC_HUMAN
NC score	0.081370 (rank : 162)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	266	Target Neighborhood Hits	276	Shared Neighborhood Hits	23
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ZFY21_MOUSE
NC score	0.081103 (rank : 163)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	266	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

CRKL_MOUSE
NC score	0.081083 (rank : 164)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

RGS3_HUMAN
NC score	0.081000 (rank : 165)	θ value	0.365318 (rank : 92)
Query Neighborhood Hits	266	Target Neighborhood Hits	1375	Shared Neighborhood Hits	147
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PLCG1_MOUSE
NC score	0.080900 (rank : 166)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	266	Target Neighborhood Hits	314	Shared Neighborhood Hits	18
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

ABI1_MOUSE
NC score	0.080022 (rank : 167)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	266	Target Neighborhood Hits	246	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ZN385_HUMAN
NC score	0.080002 (rank : 168)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	266	Target Neighborhood Hits	614	Shared Neighborhood Hits	109
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

HGS_HUMAN
NC score	0.079897 (rank : 169)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	266	Target Neighborhood Hits	517	Shared Neighborhood Hits	50
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

STAC_MOUSE
NC score	0.079866 (rank : 170)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	266	Target Neighborhood Hits	268	Shared Neighborhood Hits	23
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

HCLS1_HUMAN
NC score	0.079423 (rank : 171)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	266	Target Neighborhood Hits	358	Shared Neighborhood Hits	44
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ZFY21_HUMAN
NC score	0.079375 (rank : 172)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	266	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

HGS_MOUSE
NC score	0.079073 (rank : 173)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	266	Target Neighborhood Hits	589	Shared Neighborhood Hits	51
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

GRIN1_HUMAN
NC score	0.078899 (rank : 174)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	266	Target Neighborhood Hits	681	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PLCG1_HUMAN
NC score	0.078664 (rank : 175)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	266	Target Neighborhood Hits	293	Shared Neighborhood Hits	18
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

REPS2_HUMAN
NC score	0.078553 (rank : 176)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	266	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

PPIP1_HUMAN
NC score	0.078456 (rank : 177)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	266	Target Neighborhood Hits	389	Shared Neighborhood Hits	24
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SCAR3_HUMAN
NC score	0.078088 (rank : 178)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	266	Target Neighborhood Hits	205	Shared Neighborhood Hits	63
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

HCLS1_MOUSE
NC score	0.077491 (rank : 179)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	266	Target Neighborhood Hits	329	Shared Neighborhood Hits	36
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

REPS2_MOUSE
NC score	0.077304 (rank : 180)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	266	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

ABI1_HUMAN
NC score	0.076993 (rank : 181)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	266	Target Neighborhood Hits	257	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

RBNS5_HUMAN
NC score	0.076944 (rank : 182)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

BCL9_HUMAN
NC score	0.076723 (rank : 183)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	266	Target Neighborhood Hits	1008	Shared Neighborhood Hits	119
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

COFA1_MOUSE
NC score	0.076292 (rank : 184)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	266	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

BI2L1_HUMAN
NC score	0.076149 (rank : 185)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	266	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

IASPP_MOUSE
NC score	0.075896 (rank : 186)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	266	Target Neighborhood Hits	1024	Shared Neighborhood Hits	114
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

STAM1_MOUSE
NC score	0.075556 (rank : 187)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	266	Target Neighborhood Hits	273	Shared Neighborhood Hits	23
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

PPIP1_MOUSE
NC score	0.075419 (rank : 188)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	266	Target Neighborhood Hits	377	Shared Neighborhood Hits	26
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SCAR3_MOUSE
NC score	0.075314 (rank : 189)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	266	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

STAM1_HUMAN
NC score	0.075285 (rank : 190)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	266	Target Neighborhood Hits	271	Shared Neighborhood Hits	22
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

NCF4_MOUSE
NC score	0.074915 (rank : 191)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	266	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

COFA1_HUMAN
NC score	0.074727 (rank : 192)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	266	Target Neighborhood Hits	292	Shared Neighborhood Hits	75
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

SRC8_HUMAN
NC score	0.074445 (rank : 193)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	266	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

ABI3_HUMAN
NC score	0.074181 (rank : 194)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	266	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ADIPO_MOUSE
NC score	0.074145 (rank : 195)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	266	Target Neighborhood Hits	182	Shared Neighborhood Hits	54
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

EMID1_HUMAN
NC score	0.074073 (rank : 196)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	266	Target Neighborhood Hits	215	Shared Neighborhood Hits	62
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

RPP25_HUMAN
NC score	0.074048 (rank : 197)	θ value	0.00228821 (rank : 51)
Query Neighborhood Hits	266	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BUL9, Q9NX88	Gene names	RPP25
Domain Architecture	No domain graphic available
Description	Ribonuclease P protein subunit p25 (EC 3.1.26.5) (RNase P protein subunit p25).

NOXO1_MOUSE
NC score	0.074028 (rank : 198)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	266	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

SON_HUMAN
NC score	0.073981 (rank : 199)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	266	Target Neighborhood Hits	1568	Shared Neighborhood Hits	144
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SRC8_MOUSE
NC score	0.073927 (rank : 200)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	266	Target Neighborhood Hits	292	Shared Neighborhood Hits	21
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

NCF4_HUMAN
NC score	0.073914 (rank : 201)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	266	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

MARCO_HUMAN
NC score	0.073574 (rank : 202)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	266	Target Neighborhood Hits	199	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

CRK_MOUSE
NC score	0.073268 (rank : 203)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	266	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

MLL2_HUMAN
NC score	0.072894 (rank : 204)	θ value	0.0330416 (rank : 67)
Query Neighborhood Hits	266	Target Neighborhood Hits	1788	Shared Neighborhood Hits	134
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

COEA1_HUMAN
NC score	0.072753 (rank : 205)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	266	Target Neighborhood Hits	427	Shared Neighborhood Hits	64
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

EMID2_HUMAN
NC score	0.072258 (rank : 206)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	266	Target Neighborhood Hits	226	Shared Neighborhood Hits	66
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

STAC3_MOUSE
NC score	0.072119 (rank : 207)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	266	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

ABI3_MOUSE
NC score	0.071689 (rank : 208)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	266	Target Neighborhood Hits	227	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ADIPO_HUMAN
NC score	0.071686 (rank : 209)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	266	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

STAC3_HUMAN
NC score	0.071539 (rank : 210)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	266	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAM2_MOUSE
NC score	0.071399 (rank : 211)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	266	Target Neighborhood Hits	285	Shared Neighborhood Hits	21
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

CRK_HUMAN
NC score	0.071036 (rank : 212)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	266	Target Neighborhood Hits	308	Shared Neighborhood Hits	19
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

PRRT3_HUMAN
NC score	0.070698 (rank : 213)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	266	Target Neighborhood Hits	998	Shared Neighborhood Hits	124
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

STAM2_HUMAN
NC score	0.070548 (rank : 214)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	266	Target Neighborhood Hits	288	Shared Neighborhood Hits	22
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

C1QA_HUMAN
NC score	0.070318 (rank : 215)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	266	Target Neighborhood Hits	179	Shared Neighborhood Hits	49
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

C1QA_MOUSE
NC score	0.070126 (rank : 216)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	266	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	P98086	Gene names	C1qa
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

GRAP2_HUMAN
NC score	0.069680 (rank : 217)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	266	Target Neighborhood Hits	304	Shared Neighborhood Hits	20
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

C1QC_MOUSE
NC score	0.069439 (rank : 218)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	266	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

REPS1_MOUSE
NC score	0.069120 (rank : 219)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	266	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RBNS5_MOUSE
NC score	0.069059 (rank : 220)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	266	Target Neighborhood Hits	266	Shared Neighborhood Hits	24
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

GRAP2_MOUSE
NC score	0.069026 (rank : 221)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	266	Target Neighborhood Hits	297	Shared Neighborhood Hits	19
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

EDA_HUMAN
NC score	0.068849 (rank : 222)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	266	Target Neighborhood Hits	134	Shared Neighborhood Hits	59
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

SFTPD_HUMAN
NC score	0.068807 (rank : 223)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	266	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	P35247, Q86YK9, Q9UCJ2, Q9UCJ3	Gene names	SFTPD, PSPD, SFTP4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

TCGAP_HUMAN
NC score	0.068797 (rank : 224)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	266	Target Neighborhood Hits	872	Shared Neighborhood Hits	107
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

C1QB_MOUSE
NC score	0.068654 (rank : 225)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	266	Target Neighborhood Hits	126	Shared Neighborhood Hits	49
SwissProt Accessions	P14106	Gene names	C1qb
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

EDA_MOUSE
NC score	0.068646 (rank : 226)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	266	Target Neighborhood Hits	141	Shared Neighborhood Hits	57
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

C1QT7_MOUSE
NC score	0.068441 (rank : 227)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	266	Target Neighborhood Hits	124	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BVD7, Q8CHX9	Gene names	C1qtnf7, Ctrp7
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

SH3G3_MOUSE
NC score	0.068426 (rank : 228)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	266	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

PLCG2_HUMAN
NC score	0.068398 (rank : 229)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	266	Target Neighborhood Hits	280	Shared Neighborhood Hits	15
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

RPTN_MOUSE
NC score	0.068030 (rank : 230)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	266	Target Neighborhood Hits	650	Shared Neighborhood Hits	75
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

C1QT2_HUMAN
NC score	0.068014 (rank : 231)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	266	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXJ5	Gene names	C1QTNF2, CTRP2
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 2 precursor.

RHPN1_MOUSE
NC score	0.067841 (rank : 232)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	266	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

DIDO1_HUMAN
NC score	0.067769 (rank : 233)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	266	Target Neighborhood Hits	960	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EMID2_MOUSE
NC score	0.067547 (rank : 234)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	266	Target Neighborhood Hits	201	Shared Neighborhood Hits	61
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

C1QB_HUMAN
NC score	0.067487 (rank : 235)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	266	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	P02746, Q5T959, Q96H17	Gene names	C1QB
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

CTHR1_HUMAN
NC score	0.067453 (rank : 236)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	266	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
NC score	0.067336 (rank : 237)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	266	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

GLDN_HUMAN
NC score	0.067108 (rank : 238)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	266	Target Neighborhood Hits	159	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

GLDN_MOUSE
NC score	0.066843 (rank : 239)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	266	Target Neighborhood Hits	155	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

CO6A3_HUMAN
NC score	0.066810 (rank : 240)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	266	Target Neighborhood Hits	317	Shared Neighborhood Hits	56
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

BI2L1_MOUSE
NC score	0.066691 (rank : 241)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	266	Target Neighborhood Hits	197	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

SH3G3_HUMAN
NC score	0.066658 (rank : 242)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	266	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

C1QT7_HUMAN
NC score	0.066624 (rank : 243)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	266	Target Neighborhood Hits	119	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXJ2	Gene names	C1QTNF7, CTRP7
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

SRRM2_MOUSE
NC score	0.066616 (rank : 244)	θ value	0.00102713 (rank : 50)
Query Neighborhood Hits	266	Target Neighborhood Hits	1470	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

REPS1_HUMAN
NC score	0.066446 (rank : 245)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	266	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

LASP1_HUMAN
NC score	0.066008 (rank : 246)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	266	Target Neighborhood Hits	293	Shared Neighborhood Hits	20
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

C1QC_HUMAN
NC score	0.065908 (rank : 247)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	266	Target Neighborhood Hits	124	Shared Neighborhood Hits	48
SwissProt Accessions	P02747, Q7Z502, Q96DL2, Q96H05	Gene names	C1QC, C1QG
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

COEA1_MOUSE
NC score	0.065856 (rank : 248)	θ value	1.38821 (rank : 134)
Query Neighborhood Hits	266	Target Neighborhood Hits	402	Shared Neighborhood Hits	66
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

C1QT5_HUMAN
NC score	0.065318 (rank : 249)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	266	Target Neighborhood Hits	137	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BXJ0, Q8N6P2, Q9UFX4	Gene names	C1QTNF5, CTRP5
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

DBNL_HUMAN
NC score	0.065303 (rank : 250)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	266	Target Neighborhood Hits	244	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

COKA1_HUMAN
NC score	0.065218 (rank : 251)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	266	Target Neighborhood Hits	403	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

SFTPD_MOUSE
NC score	0.065100 (rank : 252)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	266	Target Neighborhood Hits	217	Shared Neighborhood Hits	55
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SH3G1_HUMAN
NC score	0.064668 (rank : 253)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

LASP1_MOUSE
NC score	0.064251 (rank : 254)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	266	Target Neighborhood Hits	297	Shared Neighborhood Hits	21
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

RHPN1_HUMAN
NC score	0.063347 (rank : 255)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	266	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SHAN2_HUMAN
NC score	0.063202 (rank : 256)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	266	Target Neighborhood Hits	346	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

MSRE_HUMAN
NC score	0.063135 (rank : 257)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	266	Target Neighborhood Hits	298	Shared Neighborhood Hits	54
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

TCGAP_MOUSE
NC score	0.063133 (rank : 258)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	266	Target Neighborhood Hits	409	Shared Neighborhood Hits	55
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PCLO_MOUSE
NC score	0.063115 (rank : 259)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	266	Target Neighborhood Hits	2275	Shared Neighborhood Hits	157
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SSBP4_HUMAN
NC score	0.063012 (rank : 260)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	266	Target Neighborhood Hits	753	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

AHI1_HUMAN
NC score	0.062949 (rank : 261)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	266	Target Neighborhood Hits	537	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

SH3G2_HUMAN
NC score	0.062948 (rank : 262)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	266	Target Neighborhood Hits	324	Shared Neighborhood Hits	19
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G1_MOUSE
NC score	0.062759 (rank : 263)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	266	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

NOXO1_HUMAN
NC score	0.062399 (rank : 264)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	266	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

C1QT5_MOUSE
NC score	0.062211 (rank : 265)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	266	Target Neighborhood Hits	131	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

SH3G2_MOUSE
NC score	0.062087 (rank : 266)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	266	Target Neighborhood Hits	319	Shared Neighborhood Hits	19
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

AHI1_MOUSE
NC score	0.061301 (rank : 267)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	266	Target Neighborhood Hits	496	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

DBNL_MOUSE
NC score	0.061057 (rank : 268)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	266	Target Neighborhood Hits	306	Shared Neighborhood Hits	21
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

EFS_MOUSE
NC score	0.060849 (rank : 269)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	266	Target Neighborhood Hits	389	Shared Neighborhood Hits	44
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ELN_MOUSE
NC score	0.060496 (rank : 270)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	266	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

PCLO_HUMAN
NC score	0.060395 (rank : 271)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	266	Target Neighborhood Hits	2046	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NEBL_HUMAN
NC score	0.059905 (rank : 272)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	266	Target Neighborhood Hits	457	Shared Neighborhood Hits	27
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

OSTF1_HUMAN
NC score	0.059687 (rank : 273)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	266	Target Neighborhood Hits	466	Shared Neighborhood Hits	20
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

BCAR1_HUMAN
NC score	0.058842 (rank : 274)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	266	Target Neighborhood Hits	554	Shared Neighborhood Hits	65
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

OSTF1_MOUSE
NC score	0.058727 (rank : 275)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	266	Target Neighborhood Hits	467	Shared Neighborhood Hits	20
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

BSN_MOUSE
NC score	0.058692 (rank : 276)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	266	Target Neighborhood Hits	2057	Shared Neighborhood Hits	156
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

C1QRF_MOUSE
NC score	0.058647 (rank : 277)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	266	Target Neighborhood Hits	140	Shared Neighborhood Hits	55
SwissProt Accessions	O88992	Gene names	C1ql1, C1qrf, Crf
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

C1QRF_HUMAN
NC score	0.058347 (rank : 278)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	266	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	O75973	Gene names	C1QL1, C1QRF, CRF
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

CGRE1_HUMAN
NC score	0.058346 (rank : 279)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	266	Target Neighborhood Hits	354	Shared Neighborhood Hits	77
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

COCA1_HUMAN
NC score	0.058205 (rank : 280)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	266	Target Neighborhood Hits	458	Shared Neighborhood Hits	70
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

PACN3_MOUSE
NC score	0.058201 (rank : 281)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	266	Target Neighborhood Hits	380	Shared Neighborhood Hits	24
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PACN3_HUMAN
NC score	0.058187 (rank : 282)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	266	Target Neighborhood Hits	385	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

NPHP1_HUMAN
NC score	0.057903 (rank : 283)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	266	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

C1QL3_MOUSE
NC score	0.057894 (rank : 284)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	266	Target Neighborhood Hits	127	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESN4	Gene names	C1ql3, C1ql
Domain Architecture
Description	Complement C1q-like protein 3 precursor (Gliacolin).

COCA1_MOUSE
NC score	0.057825 (rank : 285)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	266	Target Neighborhood Hits	467	Shared Neighborhood Hits	69
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

BAIP2_MOUSE
NC score	0.057240 (rank : 286)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	266	Target Neighborhood Hits	185	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

PDZD3_HUMAN
NC score	0.057223 (rank : 287)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	266	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

BCAR1_MOUSE
NC score	0.057196 (rank : 288)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	266	Target Neighborhood Hits	438	Shared Neighborhood Hits	50
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

C1QT3_MOUSE
NC score	0.057084 (rank : 289)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	266	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ES30	Gene names	C1qtnf3, Cors26, Ctrp3
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 3 precursor (Secretory protein CORS26).

MTSS1_MOUSE
NC score	0.056930 (rank : 290)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	266	Target Neighborhood Hits	592	Shared Neighborhood Hits	105
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

SFTPA_MOUSE
NC score	0.056849 (rank : 291)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	266	Target Neighborhood Hits	169	Shared Neighborhood Hits	48
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

EFS_HUMAN
NC score	0.056828 (rank : 292)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	266	Target Neighborhood Hits	348	Shared Neighborhood Hits	37
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

C1QT1_HUMAN
NC score	0.056781 (rank : 293)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	266	Target Neighborhood Hits	125	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXJ1, Q96NF2, Q9GZR4	Gene names	C1QTNF1, CTRP1
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 1 precursor (G protein-coupled receptor-interacting protein) (GIP).

C1QT3_HUMAN
NC score	0.056500 (rank : 294)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	266	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXJ4, Q6MZN1, Q96KY1	Gene names	C1QTNF3, CTRP3
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 3 precursor (Secretory protein CORS26).

PDZD1_MOUSE
NC score	0.056426 (rank : 295)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	266	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

BAIP2_HUMAN
NC score	0.056421 (rank : 296)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	266	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

ZFY19_HUMAN
NC score	0.056370 (rank : 297)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	266	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

RIMB2_HUMAN
NC score	0.055679 (rank : 298)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	266	Target Neighborhood Hits	263	Shared Neighborhood Hits	25
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

TCOF_MOUSE
NC score	0.055607 (rank : 299)	θ value	0.0252991 (rank : 64)
Query Neighborhood Hits	266	Target Neighborhood Hits	471	Shared Neighborhood Hits	39
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

RIMB2_MOUSE
NC score	0.055367 (rank : 300)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	266	Target Neighborhood Hits	246	Shared Neighborhood Hits	20
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

LMO7_HUMAN
NC score	0.055232 (rank : 301)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	266	Target Neighborhood Hits	507	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

CT032_HUMAN
NC score	0.055176 (rank : 302)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	266	Target Neighborhood Hits	235	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

UN13A_HUMAN
NC score	0.054998 (rank : 303)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	266	Target Neighborhood Hits	285	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

EP15R_MOUSE
NC score	0.054303 (rank : 304)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	266	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

NPHP1_MOUSE
NC score	0.054098 (rank : 305)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	266	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

RUFY2_MOUSE
NC score	0.053894 (rank : 306)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	266	Target Neighborhood Hits	820	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SON_MOUSE
NC score	0.053818 (rank : 307)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	266	Target Neighborhood Hits	957	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ZFY19_MOUSE
NC score	0.053601 (rank : 308)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	266	Target Neighborhood Hits	143	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

NCOA6_HUMAN
NC score	0.053561 (rank : 309)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	266	Target Neighborhood Hits	1202	Shared Neighborhood Hits	117
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PACN2_MOUSE
NC score	0.053493 (rank : 310)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	266	Target Neighborhood Hits	382	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

C1QT6_HUMAN
NC score	0.053009 (rank : 311)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	266	Target Neighborhood Hits	122	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXI9	Gene names	C1QTNF6, CTRP6
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 6 precursor.

P85A_HUMAN
NC score	0.052819 (rank : 312)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	266	Target Neighborhood Hits	479	Shared Neighborhood Hits	24
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PACN2_HUMAN
NC score	0.052639 (rank : 313)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	266	Target Neighborhood Hits	339	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PEX13_HUMAN
NC score	0.052637 (rank : 314)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	266	Target Neighborhood Hits	128	Shared Neighborhood Hits	15
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

RHG04_HUMAN
NC score	0.052600 (rank : 315)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RUFY2_HUMAN
NC score	0.052495 (rank : 316)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	266	Target Neighborhood Hits	1208	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

EHD1_HUMAN
NC score	0.052335 (rank : 317)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	266	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4M9, O14611, Q9UNR3	Gene names	EHD1, PAST, PAST1
Domain Architecture
Description	EH-domain-containing protein 1 (Testilin) (hPAST1).

MSRE_MOUSE
NC score	0.052275 (rank : 318)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	266	Target Neighborhood Hits	307	Shared Neighborhood Hits	54
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

PEX13_MOUSE
NC score	0.052270 (rank : 319)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	266	Target Neighborhood Hits	126	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

EHD1_MOUSE
NC score	0.052246 (rank : 320)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	266	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVK4	Gene names	Ehd1, Past1
Domain Architecture
Description	EH-domain-containing protein 1 (mPAST1).

BSN_HUMAN
NC score	0.052146 (rank : 321)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	266	Target Neighborhood Hits	1537	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CASL_HUMAN
NC score	0.052063 (rank : 322)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	266	Target Neighborhood Hits	259	Shared Neighborhood Hits	26
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

PKHA6_HUMAN
NC score	0.051785 (rank : 323)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	266	Target Neighborhood Hits	556	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

EHD2_HUMAN
NC score	0.051753 (rank : 324)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	266	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN4, Q96CB6	Gene names	EHD2
Domain Architecture
Description	EH-domain-containing protein 2.

EHD3_HUMAN
NC score	0.051616 (rank : 325)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	266	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN3, Q8N514, Q9NZB3	Gene names	EHD3, EHD2
Domain Architecture
Description	EH-domain-containing protein 3.

P85B_HUMAN
NC score	0.051493 (rank : 326)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	266	Target Neighborhood Hits	543	Shared Neighborhood Hits	34
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PACN1_HUMAN
NC score	0.051323 (rank : 327)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	266	Target Neighborhood Hits	320	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

EMIL1_HUMAN
NC score	0.051282 (rank : 328)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	266	Target Neighborhood Hits	239	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EHD3_MOUSE
NC score	0.051258 (rank : 329)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	266	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXY6	Gene names	Ehd3, Ehd2
Domain Architecture
Description	EH-domain-containing protein 3.

PACN1_MOUSE
NC score	0.051244 (rank : 330)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	266	Target Neighborhood Hits	283	Shared Neighborhood Hits	18
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PDZD3_MOUSE
NC score	0.051240 (rank : 331)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	266	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

EP15_HUMAN
NC score	0.051229 (rank : 332)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	266	Target Neighborhood Hits	1021	Shared Neighborhood Hits	34
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

RUFY1_HUMAN
NC score	0.051150 (rank : 333)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	266	Target Neighborhood Hits	848	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

EHD4_MOUSE
NC score	0.051020 (rank : 334)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	266	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQP2	Gene names	Ehd4, Past2
Domain Architecture
Description	EH-domain-containing protein 4 (mPAST2).

IASPP_HUMAN
NC score	0.050939 (rank : 335)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	266	Target Neighborhood Hits	688	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

RUFY1_MOUSE
NC score	0.050845 (rank : 336)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	266	Target Neighborhood Hits	765	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

ZFYV1_HUMAN
NC score	0.050631 (rank : 337)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

EP15_MOUSE
NC score	0.050614 (rank : 338)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	266	Target Neighborhood Hits	820	Shared Neighborhood Hits	20
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

RIMB1_HUMAN
NC score	0.050599 (rank : 339)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	266	Target Neighborhood Hits	1479	Shared Neighborhood Hits	110
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PDZD8_HUMAN
NC score	0.050447 (rank : 340)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	266	Target Neighborhood Hits	185	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

MIA_MOUSE
NC score	0.050432 (rank : 341)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	266	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q61865, O09086, P97495	Gene names	Mia, Cdrap, Mia1
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity) (Cartilage-derived retinoic acid-sensitive protein) (CD-RAP).

MIA_HUMAN
NC score	0.050410 (rank : 342)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	266	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q16674	Gene names	MIA
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity).

NACAM_MOUSE
NC score	0.050389 (rank : 343)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	266	Target Neighborhood Hits	1866	Shared Neighborhood Hits	131
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

FYV1_HUMAN
NC score	0.050323 (rank : 344)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	266	Target Neighborhood Hits	217	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

EMIL1_MOUSE
NC score	0.050280 (rank : 345)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	266	Target Neighborhood Hits	214	Shared Neighborhood Hits	57
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

ANM2_HUMAN
NC score	0.050214 (rank : 346)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	266	Target Neighborhood Hits	175	Shared Neighborhood Hits	12
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

P85A_MOUSE
NC score	0.050182 (rank : 347)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	266	Target Neighborhood Hits	435	Shared Neighborhood Hits	22
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

USH1C_HUMAN
NC score	0.050068 (rank : 348)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	266	Target Neighborhood Hits	327	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

EP15R_HUMAN
NC score	0.050052 (rank : 349)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	266	Target Neighborhood Hits	1083	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

PDZD2_HUMAN
NC score	0.050038 (rank : 350)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	266	Target Neighborhood Hits	772	Shared Neighborhood Hits	72
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

ZIMP7_MOUSE
NC score	0.049221 (rank : 351)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	266	Target Neighborhood Hits	566	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ENAH_MOUSE
NC score	0.048487 (rank : 352)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	266	Target Neighborhood Hits	919	Shared Neighborhood Hits	61
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MAGE1_HUMAN
NC score	0.048478 (rank : 353)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	266	Target Neighborhood Hits	1389	Shared Neighborhood Hits	133
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ENAH_HUMAN
NC score	0.048369 (rank : 354)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	266	Target Neighborhood Hits	784	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PRG4_HUMAN
NC score	0.048259 (rank : 355)	θ value	0.0193708 (rank : 62)
Query Neighborhood Hits	266	Target Neighborhood Hits	764	Shared Neighborhood Hits	56
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SAPS1_HUMAN
NC score	0.046987 (rank : 356)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	266	Target Neighborhood Hits	704	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MINT_MOUSE
NC score	0.046922 (rank : 357)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	266	Target Neighborhood Hits	1514	Shared Neighborhood Hits	108
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

HRX_HUMAN
NC score	0.046566 (rank : 358)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	266	Target Neighborhood Hits	825	Shared Neighborhood Hits	58
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CCD96_HUMAN
NC score	0.046489 (rank : 359)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	266	Target Neighborhood Hits	595	Shared Neighborhood Hits	39
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

RP1L1_HUMAN
NC score	0.045884 (rank : 360)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	266	Target Neighborhood Hits	1072	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

N4BP2_HUMAN
NC score	0.045503 (rank : 361)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	266	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

CEL_HUMAN
NC score	0.045098 (rank : 362)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	266	Target Neighborhood Hits	896	Shared Neighborhood Hits	115
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

BCL7C_MOUSE
NC score	0.044068 (rank : 363)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	266	Target Neighborhood Hits	170	Shared Neighborhood Hits	43
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

PRG4_MOUSE
NC score	0.042904 (rank : 364)	θ value	0.0563607 (rank : 74)
Query Neighborhood Hits	266	Target Neighborhood Hits	624	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SHC1_HUMAN
NC score	0.042590 (rank : 365)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	266	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

MADCA_HUMAN
NC score	0.042570 (rank : 366)	θ value	0.163984 (rank : 86)
Query Neighborhood Hits	266	Target Neighborhood Hits	221	Shared Neighborhood Hits	23
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

SET1A_HUMAN
NC score	0.041994 (rank : 367)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	266	Target Neighborhood Hits	690	Shared Neighborhood Hits	51
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SYP2L_MOUSE
NC score	0.041280 (rank : 368)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	266	Target Neighborhood Hits	289	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

BAT2_MOUSE
NC score	0.040759 (rank : 369)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	266	Target Neighborhood Hits	947	Shared Neighborhood Hits	106
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SPN90_HUMAN
NC score	0.040038 (rank : 370)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	266	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

CIC_HUMAN
NC score	0.039034 (rank : 371)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	266	Target Neighborhood Hits	992	Shared Neighborhood Hits	100
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CP250_HUMAN
NC score	0.039026 (rank : 372)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	266	Target Neighborhood Hits	1805	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

TXND2_HUMAN
NC score	0.038728 (rank : 373)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	266	Target Neighborhood Hits	793	Shared Neighborhood Hits	55
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

EVPL_HUMAN
NC score	0.038374 (rank : 374)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	266	Target Neighborhood Hits	895	Shared Neighborhood Hits	31
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

SHC1_MOUSE
NC score	0.038352 (rank : 375)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	266	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

MUCDL_HUMAN
NC score	0.037407 (rank : 376)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	266	Target Neighborhood Hits	777	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

FMNL_HUMAN
NC score	0.037399 (rank : 377)	θ value	0.0961366 (rank : 78)
Query Neighborhood Hits	266	Target Neighborhood Hits	529	Shared Neighborhood Hits	50
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

SFPQ_HUMAN
NC score	0.036398 (rank : 378)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	266	Target Neighborhood Hits	986	Shared Neighborhood Hits	79
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

RP3A_HUMAN
NC score	0.036206 (rank : 379)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	266	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

MLL4_HUMAN
NC score	0.036021 (rank : 380)	θ value	0.279714 (rank : 89)
Query Neighborhood Hits	266	Target Neighborhood Hits	722	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CP250_MOUSE
NC score	0.036000 (rank : 381)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	266	Target Neighborhood Hits	1583	Shared Neighborhood Hits	49
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

ZMYM3_MOUSE
NC score	0.035093 (rank : 382)	θ value	0.0330416 (rank : 69)
Query Neighborhood Hits	266	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

JPH2_HUMAN
NC score	0.034391 (rank : 383)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	266	Target Neighborhood Hits	639	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

GSCR1_HUMAN
NC score	0.034291 (rank : 384)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	266	Target Neighborhood Hits	674	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CBP_HUMAN
NC score	0.034258 (rank : 385)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	266	Target Neighborhood Hits	941	Shared Neighborhood Hits	83
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DREB_HUMAN
NC score	0.034202 (rank : 386)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	266	Target Neighborhood Hits	450	Shared Neighborhood Hits	26
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

SFPQ_MOUSE
NC score	0.033974 (rank : 387)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	266	Target Neighborhood Hits	958	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

TCF20_MOUSE
NC score	0.032821 (rank : 388)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	266	Target Neighborhood Hits	396	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

MAGC1_HUMAN
NC score	0.032037 (rank : 389)	θ value	0.125558 (rank : 83)
Query Neighborhood Hits	266	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MAGC3_HUMAN
NC score	0.031920 (rank : 390)	θ value	0.0193708 (rank : 61)
Query Neighborhood Hits	266	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

XRCC1_MOUSE
NC score	0.031678 (rank : 391)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

CBP_MOUSE
NC score	0.030948 (rank : 392)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	266	Target Neighborhood Hits	1051	Shared Neighborhood Hits	81
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

K0310_HUMAN
NC score	0.030594 (rank : 393)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	266	Target Neighborhood Hits	420	Shared Neighborhood Hits	51
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

IF35_MOUSE
NC score	0.029692 (rank : 394)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	266	Target Neighborhood Hits	210	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

CS007_HUMAN
NC score	0.029634 (rank : 395)	θ value	0.813845 (rank : 112)
Query Neighborhood Hits	266	Target Neighborhood Hits	401	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CIC_MOUSE
NC score	0.028608 (rank : 396)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	266	Target Neighborhood Hits	742	Shared Neighborhood Hits	87
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RB6I2_MOUSE
NC score	0.028498 (rank : 397)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	266	Target Neighborhood Hits	1433	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TCF20_HUMAN
NC score	0.028340 (rank : 398)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	266	Target Neighborhood Hits	323	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

RB6I2_HUMAN
NC score	0.027110 (rank : 399)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	266	Target Neighborhood Hits	1584	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

ATN1_HUMAN
NC score	0.026916 (rank : 400)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	266	Target Neighborhood Hits	676	Shared Neighborhood Hits	56
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SYNE2_HUMAN
NC score	0.026555 (rank : 401)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	266	Target Neighborhood Hits	1323	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

MUCDL_MOUSE
NC score	0.026333 (rank : 402)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	266	Target Neighborhood Hits	461	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CF152_HUMAN
NC score	0.025291 (rank : 403)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	266	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

NCOA5_HUMAN
NC score	0.025251 (rank : 404)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	266	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

SSBP3_HUMAN
NC score	0.024893 (rank : 405)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	266	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.024893 (rank : 406)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	266	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

CUTL1_HUMAN
NC score	0.024279 (rank : 407)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	266	Target Neighborhood Hits	1574	Shared Neighborhood Hits	64
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CS029_MOUSE
NC score	0.023911 (rank : 408)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	266	Target Neighborhood Hits	201	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

RERE_MOUSE
NC score	0.022323 (rank : 409)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	266	Target Neighborhood Hits	785	Shared Neighborhood Hits	51
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CK042_HUMAN
NC score	0.022134 (rank : 410)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	266	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N5U0	Gene names	C11orf42
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf42.

CF152_MOUSE
NC score	0.022054 (rank : 411)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	266	Target Neighborhood Hits	597	Shared Neighborhood Hits	23
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

COG8_MOUSE
NC score	0.021510 (rank : 412)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	266	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

NUCKS_HUMAN
NC score	0.021174 (rank : 413)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	266	Target Neighborhood Hits	143	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

CXXC6_HUMAN
NC score	0.021173 (rank : 414)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	266	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

CBX6_HUMAN
NC score	0.021169 (rank : 415)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	266	Target Neighborhood Hits	104	Shared Neighborhood Hits	17
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

HCN2_HUMAN
NC score	0.020702 (rank : 416)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	266	Target Neighborhood Hits	369	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

SFRS8_HUMAN
NC score	0.019928 (rank : 417)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	266	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

TCAL8_MOUSE
NC score	0.019408 (rank : 418)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	266	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZY2, Q9CYP9	Gene names	Tceal8
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 8 (TCEA-like protein 8) (Transcription elongation factor S-II protein-like 8).

NASP_HUMAN
NC score	0.018609 (rank : 419)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	266	Target Neighborhood Hits	709	Shared Neighborhood Hits	35
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

LAP2B_HUMAN
NC score	0.018564 (rank : 420)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	266	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42167, Q14861	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

NEUM_MOUSE
NC score	0.018483 (rank : 421)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	266	Target Neighborhood Hits	149	Shared Neighborhood Hits	18
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

CSKI1_MOUSE
NC score	0.018070 (rank : 422)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	266	Target Neighborhood Hits	1031	Shared Neighborhood Hits	88
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

APLP1_MOUSE
NC score	0.018016 (rank : 423)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	266	Target Neighborhood Hits	130	Shared Neighborhood Hits	16
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

CSKI1_HUMAN
NC score	0.017612 (rank : 424)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	266	Target Neighborhood Hits	997	Shared Neighborhood Hits	108
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RPGF1_HUMAN
NC score	0.017435 (rank : 425)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	266	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

ZN598_HUMAN
NC score	0.017355 (rank : 426)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	266	Target Neighborhood Hits	339	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

FA13C_MOUSE
NC score	0.017354 (rank : 427)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	266	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

K2027_HUMAN
NC score	0.017160 (rank : 428)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	266	Target Neighborhood Hits	194	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

TFE3_HUMAN
NC score	0.017031 (rank : 429)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	266	Target Neighborhood Hits	190	Shared Neighborhood Hits	11
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

LARP1_HUMAN
NC score	0.016924 (rank : 430)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	266	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

LRC50_HUMAN
NC score	0.016827 (rank : 431)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	266	Target Neighborhood Hits	275	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

I17RD_HUMAN
NC score	0.016796 (rank : 432)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	266	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFM7, Q58EZ7, Q6RVF4, Q6UWI5, Q8N113, Q8NFS0, Q9UFA0	Gene names	IL17RD, IL17RLM, SEF
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor D precursor (IL-17 receptor D) (IL-17RD) (Interleukin-17D receptor) (IL-17D receptor) (IL17Rhom) (Interleukin- 17 receptor-like protein) (Sef homolog) (hSef).

RB15B_MOUSE
NC score	0.016712 (rank : 433)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	266	Target Neighborhood Hits	284	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

OSBL5_HUMAN
NC score	0.016146 (rank : 434)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	266	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

PITM3_MOUSE
NC score	0.016135 (rank : 435)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	266	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

MYBPH_MOUSE
NC score	0.016085 (rank : 436)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	266	Target Neighborhood Hits	290	Shared Neighborhood Hits	14
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

CSKI2_HUMAN
NC score	0.016080 (rank : 437)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	266	Target Neighborhood Hits	747	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ADDB_MOUSE
NC score	0.015977 (rank : 438)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	266	Target Neighborhood Hits	574	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ARI5B_HUMAN
NC score	0.015613 (rank : 439)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	266	Target Neighborhood Hits	328	Shared Neighborhood Hits	20
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

TTC28_MOUSE
NC score	0.015446 (rank : 440)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	266	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

PML_HUMAN
NC score	0.015412 (rank : 441)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	266	Target Neighborhood Hits	248	Shared Neighborhood Hits	20
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PODXL_HUMAN
NC score	0.015033 (rank : 442)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	266	Target Neighborhood Hits	191	Shared Neighborhood Hits	11
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PHF1_HUMAN
NC score	0.015008 (rank : 443)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	266	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

THAP4_MOUSE
NC score	0.014597 (rank : 444)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	266	Target Neighborhood Hits	130	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

RTN4_HUMAN
NC score	0.014333 (rank : 445)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	266	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TOIP2_HUMAN
NC score	0.014159 (rank : 446)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	266	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

SMCA4_HUMAN
NC score	0.013940 (rank : 447)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	266	Target Neighborhood Hits	597	Shared Neighborhood Hits	47
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CENG2_HUMAN
NC score	0.013862 (rank : 448)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	266	Target Neighborhood Hits	471	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

ATS14_HUMAN
NC score	0.013676 (rank : 449)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	266	Target Neighborhood Hits	382	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

NFAC1_HUMAN
NC score	0.013652 (rank : 450)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	266	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

HCN4_HUMAN
NC score	0.013518 (rank : 451)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	266	Target Neighborhood Hits	303	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

CDAN1_HUMAN
NC score	0.013462 (rank : 452)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	266	Target Neighborhood Hits	92	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

OSBL5_MOUSE
NC score	0.013168 (rank : 453)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	266	Target Neighborhood Hits	77	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

SEM6C_MOUSE
NC score	0.013154 (rank : 454)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	266	Target Neighborhood Hits	352	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

CENG2_MOUSE
NC score	0.013117 (rank : 455)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	266	Target Neighborhood Hits	463	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

PITM3_HUMAN
NC score	0.012951 (rank : 456)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	266	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZ71, Q59GH9, Q9NPQ4	Gene names	PITPNM3, NIR1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

KIF5C_HUMAN
NC score	0.012690 (rank : 457)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	266	Target Neighborhood Hits	974	Shared Neighborhood Hits	32
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

OXRP_HUMAN
NC score	0.012091 (rank : 458)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	266	Target Neighborhood Hits	544	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SREC2_MOUSE
NC score	0.011716 (rank : 459)	θ value	0.0330416 (rank : 68)
Query Neighborhood Hits	266	Target Neighborhood Hits	605	Shared Neighborhood Hits	23
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CAH9_MOUSE
NC score	0.011684 (rank : 460)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	266	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHB5, Q8K1G1, Q8VDE4	Gene names	Ca9, Car9
Domain Architecture
Description	Carbonic anhydrase 9 precursor (EC 4.2.1.1) (Carbonic anhydrase IX) (Carbonate dehydratase IX) (CA-IX) (CAIX) (Membrane antigen MN homolog).

PITM1_HUMAN
NC score	0.011655 (rank : 461)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	266	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

ATBF1_MOUSE
NC score	0.011621 (rank : 462)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	266	Target Neighborhood Hits	1841	Shared Neighborhood Hits	72
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

FBX34_MOUSE
NC score	0.011400 (rank : 463)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	266	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

EP400_HUMAN
NC score	0.011341 (rank : 464)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	266	Target Neighborhood Hits	556	Shared Neighborhood Hits	52
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

CAF1B_MOUSE
NC score	0.010061 (rank : 465)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	266	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

ESPL1_HUMAN
NC score	0.009775 (rank : 466)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	266	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

PLXB1_MOUSE
NC score	0.009081 (rank : 467)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	266	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

JPH4_HUMAN
NC score	0.008966 (rank : 468)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	266	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	Q96JJ6, Q8ND44, Q96DQ0	Gene names	JPH4, JPHL1, KIAA1831
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

NCA11_MOUSE
NC score	0.008948 (rank : 469)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	266	Target Neighborhood Hits	661	Shared Neighborhood Hits	41
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

HXA3_MOUSE
NC score	0.008915 (rank : 470)	θ value	1.38821 (rank : 136)
Query Neighborhood Hits	266	Target Neighborhood Hits	558	Shared Neighborhood Hits	34
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

FOXP4_HUMAN
NC score	0.008899 (rank : 471)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	266	Target Neighborhood Hits	246	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

MRCKG_MOUSE
NC score	0.008762 (rank : 472)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	266	Target Neighborhood Hits	1466	Shared Neighborhood Hits	37
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

RC3H1_MOUSE
NC score	0.008698 (rank : 473)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	266	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TITIN_HUMAN
NC score	0.008684 (rank : 474)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	266	Target Neighborhood Hits	2923	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CAF1B_HUMAN
NC score	0.008552 (rank : 475)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	266	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

SPEG_MOUSE
NC score	0.008018 (rank : 476)	θ value	0.813845 (rank : 120)
Query Neighborhood Hits	266	Target Neighborhood Hits	1959	Shared Neighborhood Hits	91
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PRDM8_HUMAN
NC score	0.008011 (rank : 477)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	266	Target Neighborhood Hits	591	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQV8, Q6IQ36	Gene names	PRDM8, PFM5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

CHD4_MOUSE
NC score	0.007980 (rank : 478)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	266	Target Neighborhood Hits	408	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

GANAB_MOUSE
NC score	0.007394 (rank : 479)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	266	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

SRPK2_MOUSE
NC score	0.007359 (rank : 480)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	266	Target Neighborhood Hits	765	Shared Neighborhood Hits	21
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

PIAS4_HUMAN
NC score	0.007356 (rank : 481)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	266	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

VPS54_MOUSE
NC score	0.006877 (rank : 482)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	266	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

PO3F2_MOUSE
NC score	0.005390 (rank : 483)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	266	Target Neighborhood Hits	313	Shared Neighborhood Hits	10
SwissProt Accessions	P31360	Gene names	Pou3f2, Brn-2, Brn2, Otf7
Domain Architecture
Description	POU domain, class 3, transcription factor 2 (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Protein Brn-2).

HXA3_HUMAN
NC score	0.005377 (rank : 484)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	266	Target Neighborhood Hits	535	Shared Neighborhood Hits	31
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

FRAS1_MOUSE
NC score	0.004145 (rank : 485)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	266	Target Neighborhood Hits	747	Shared Neighborhood Hits	15
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PO2F1_MOUSE
NC score	0.003517 (rank : 486)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	266	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

SALL3_HUMAN
NC score	0.003277 (rank : 487)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	266	Target Neighborhood Hits	1066	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

LATS2_HUMAN
NC score	0.001982 (rank : 488)	θ value	0.279714 (rank : 88)
Query Neighborhood Hits	266	Target Neighborhood Hits	884	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

CSPG3_MOUSE
NC score	-0.000200 (rank : 489)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	266	Target Neighborhood Hits	657	Shared Neighborhood Hits	21
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FOG1_HUMAN
NC score	-0.000634 (rank : 490)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	266	Target Neighborhood Hits	981	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

NOTC3_MOUSE
NC score	-0.000870 (rank : 491)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	266	Target Neighborhood Hits	975	Shared Neighborhood Hits	28
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PAK4_HUMAN
NC score	-0.001059 (rank : 492)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	266	Target Neighborhood Hits	924	Shared Neighborhood Hits	29
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

MK15_HUMAN
NC score	-0.001409 (rank : 493)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	266	Target Neighborhood Hits	1038	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

POGZ_MOUSE
NC score	-0.003964 (rank : 494)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	266	Target Neighborhood Hits	765	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

ZBT40_HUMAN
NC score	-0.005004 (rank : 495)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	266	Target Neighborhood Hits	949	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.