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Network neighborhood for query Sequence : ITSN2_MOUSE

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ITSN2_MOUSE
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ITSN1_HUMAN
θ value	0 (rank : 1)	NC score	0.933991 (rank : 3)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1757	Shared Neighborhood Hits	1093
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	0 (rank : 2)	NC score	0.928591 (rank : 4)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1669	Shared Neighborhood Hits	1073
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
θ value	0 (rank : 3)	NC score	0.962207 (rank : 2)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1173	Shared Neighborhood Hits	1032
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1371	Shared Neighborhood Hits	1371
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ARHGC_MOUSE
θ value	4.57862e-28 (rank : 5)	NC score	0.445007 (rank : 225)
Query Neighborhood Hits	1371	Target Neighborhood Hits	344	Shared Neighborhood Hits	147
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_HUMAN
θ value	1.33217e-27 (rank : 6)	NC score	0.447962 (rank : 217)
Query Neighborhood Hits	1371	Target Neighborhood Hits	351	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGB_HUMAN
θ value	7.30988e-26 (rank : 7)	NC score	0.452679 (rank : 199)
Query Neighborhood Hits	1371	Target Neighborhood Hits	375	Shared Neighborhood Hits	135
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGG_MOUSE
θ value	3.62785e-25 (rank : 8)	NC score	0.506643 (rank : 65)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	114
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHG1_MOUSE
θ value	6.84181e-24 (rank : 9)	NC score	0.439738 (rank : 238)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	85
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG1_HUMAN
θ value	2.59989e-23 (rank : 10)	NC score	0.461273 (rank : 181)
Query Neighborhood Hits	1371	Target Neighborhood Hits	176	Shared Neighborhood Hits	74
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHGG_HUMAN
θ value	2.20094e-22 (rank : 11)	NC score	0.497251 (rank : 94)
Query Neighborhood Hits	1371	Target Neighborhood Hits	129	Shared Neighborhood Hits	110
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

EP15_MOUSE
θ value	2.20094e-22 (rank : 12)	NC score	0.538355 (rank : 17)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	524
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ARHG3_HUMAN
θ value	1.09232e-21 (rank : 13)	NC score	0.488168 (rank : 116)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG7_HUMAN
θ value	1.09232e-21 (rank : 14)	NC score	0.579482 (rank : 6)
Query Neighborhood Hits	1371	Target Neighborhood Hits	347	Shared Neighborhood Hits	284
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

EP15_HUMAN
θ value	1.42661e-21 (rank : 15)	NC score	0.543408 (rank : 16)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1021	Shared Neighborhood Hits	611
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

NGEF_MOUSE
θ value	1.86321e-21 (rank : 16)	NC score	0.506476 (rank : 66)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	158
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHG3_MOUSE
θ value	2.43343e-21 (rank : 17)	NC score	0.486435 (rank : 120)
Query Neighborhood Hits	1371	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG7_MOUSE
θ value	2.43343e-21 (rank : 18)	NC score	0.593367 (rank : 5)
Query Neighborhood Hits	1371	Target Neighborhood Hits	396	Shared Neighborhood Hits	342
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG8_HUMAN
θ value	5.42112e-21 (rank : 19)	NC score	0.484618 (rank : 124)
Query Neighborhood Hits	1371	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

NGEF_HUMAN
θ value	1.5773e-20 (rank : 20)	NC score	0.510113 (rank : 54)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	143
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NCK1_HUMAN
θ value	2.69047e-20 (rank : 21)	NC score	0.456362 (rank : 191)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	224
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

ARHG4_MOUSE
θ value	3.51386e-20 (rank : 22)	NC score	0.532794 (rank : 18)
Query Neighborhood Hits	1371	Target Neighborhood Hits	185	Shared Neighborhood Hits	173
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_HUMAN
θ value	4.58923e-20 (rank : 23)	NC score	0.564485 (rank : 9)
Query Neighborhood Hits	1371	Target Neighborhood Hits	242	Shared Neighborhood Hits	223
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG8_MOUSE
θ value	4.58923e-20 (rank : 24)	NC score	0.480199 (rank : 142)
Query Neighborhood Hits	1371	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHG9_HUMAN
θ value	5.99374e-20 (rank : 25)	NC score	0.555760 (rank : 12)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	216
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	7.82807e-20 (rank : 26)	NC score	0.555107 (rank : 13)
Query Neighborhood Hits	1371	Target Neighborhood Hits	234	Shared Neighborhood Hits	218
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG6_HUMAN
θ value	1.74391e-19 (rank : 27)	NC score	0.560207 (rank : 11)
Query Neighborhood Hits	1371	Target Neighborhood Hits	376	Shared Neighborhood Hits	317
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

EP15R_MOUSE
θ value	2.97466e-19 (rank : 28)	NC score	0.546257 (rank : 15)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1135	Shared Neighborhood Hits	634
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

ARHG6_MOUSE
θ value	3.88503e-19 (rank : 29)	NC score	0.563980 (rank : 10)
Query Neighborhood Hits	1371	Target Neighborhood Hits	394	Shared Neighborhood Hits	340
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

SH3K1_HUMAN
θ value	3.88503e-19 (rank : 30)	NC score	0.515351 (rank : 32)
Query Neighborhood Hits	1371	Target Neighborhood Hits	341	Shared Neighborhood Hits	263
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

TIAM1_MOUSE
θ value	7.32683e-18 (rank : 31)	NC score	0.441303 (rank : 235)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	89
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

CD2AP_MOUSE
θ value	2.13179e-17 (rank : 32)	NC score	0.505246 (rank : 69)
Query Neighborhood Hits	1371	Target Neighborhood Hits	336	Shared Neighborhood Hits	249
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

NCK2_HUMAN
θ value	2.13179e-17 (rank : 33)	NC score	0.449943 (rank : 210)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	214
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

RGNEF_MOUSE
θ value	2.13179e-17 (rank : 34)	NC score	0.520580 (rank : 23)
Query Neighborhood Hits	1371	Target Neighborhood Hits	641	Shared Neighborhood Hits	416
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

EP15R_HUMAN
θ value	4.74913e-17 (rank : 35)	NC score	0.547224 (rank : 14)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1083	Shared Neighborhood Hits	626
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

SH3K1_MOUSE
θ value	6.20254e-17 (rank : 36)	NC score	0.501809 (rank : 81)
Query Neighborhood Hits	1371	Target Neighborhood Hits	332	Shared Neighborhood Hits	261
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SRBS1_MOUSE
θ value	1.38178e-16 (rank : 37)	NC score	0.458353 (rank : 184)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	232
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PREX1_HUMAN
θ value	3.07829e-16 (rank : 38)	NC score	0.451891 (rank : 202)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

FGD6_MOUSE
θ value	4.02038e-16 (rank : 39)	NC score	0.368921 (rank : 423)
Query Neighborhood Hits	1371	Target Neighborhood Hits	282	Shared Neighborhood Hits	112
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

DNMBP_MOUSE
θ value	5.25075e-16 (rank : 40)	NC score	0.575997 (rank : 8)
Query Neighborhood Hits	1371	Target Neighborhood Hits	435	Shared Neighborhood Hits	297
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

CD2AP_HUMAN
θ value	8.95645e-16 (rank : 41)	NC score	0.503158 (rank : 76)
Query Neighborhood Hits	1371	Target Neighborhood Hits	315	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

FGD4_HUMAN
θ value	1.99529e-15 (rank : 42)	NC score	0.417585 (rank : 305)
Query Neighborhood Hits	1371	Target Neighborhood Hits	219	Shared Neighborhood Hits	111
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

TIAM1_HUMAN
θ value	1.99529e-15 (rank : 43)	NC score	0.436694 (rank : 244)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	100
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARHG2_MOUSE
θ value	3.40345e-15 (rank : 44)	NC score	0.439396 (rank : 240)
Query Neighborhood Hits	1371	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG2_HUMAN
θ value	5.8054e-15 (rank : 45)	NC score	0.421538 (rank : 295)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	95
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

FGD6_HUMAN
θ value	5.8054e-15 (rank : 46)	NC score	0.360896 (rank : 442)
Query Neighborhood Hits	1371	Target Neighborhood Hits	237	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

ARHGA_HUMAN
θ value	7.58209e-15 (rank : 47)	NC score	0.423464 (rank : 289)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	115
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	7.58209e-15 (rank : 48)	NC score	0.406665 (rank : 334)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	84
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

EHD2_HUMAN
θ value	7.58209e-15 (rank : 49)	NC score	0.254964 (rank : 675)
Query Neighborhood Hits	1371	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZN4, Q96CB6	Gene names	EHD2
Domain Architecture
Description	EH-domain-containing protein 2.

VINEX_HUMAN
θ value	9.90251e-15 (rank : 50)	NC score	0.466967 (rank : 171)
Query Neighborhood Hits	1371	Target Neighborhood Hits	270	Shared Neighborhood Hits	215
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

EHD1_HUMAN
θ value	1.29331e-14 (rank : 51)	NC score	0.255546 (rank : 673)
Query Neighborhood Hits	1371	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4M9, O14611, Q9UNR3	Gene names	EHD1, PAST, PAST1
Domain Architecture
Description	EH-domain-containing protein 1 (Testilin) (hPAST1).

EHD1_MOUSE
θ value	1.68911e-14 (rank : 52)	NC score	0.255342 (rank : 674)
Query Neighborhood Hits	1371	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WVK4	Gene names	Ehd1, Past1
Domain Architecture
Description	EH-domain-containing protein 1 (mPAST1).

VINEX_MOUSE
θ value	1.68911e-14 (rank : 53)	NC score	0.463071 (rank : 178)
Query Neighborhood Hits	1371	Target Neighborhood Hits	286	Shared Neighborhood Hits	213
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

CCD46_MOUSE
θ value	4.91457e-14 (rank : 54)	NC score	0.525245 (rank : 20)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1405	Shared Neighborhood Hits	764
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

REPS2_HUMAN
θ value	4.91457e-14 (rank : 55)	NC score	0.288696 (rank : 586)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

STK10_MOUSE
θ value	4.91457e-14 (rank : 56)	NC score	0.244372 (rank : 714)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2132	Shared Neighborhood Hits	750
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ARHG5_HUMAN
θ value	6.41864e-14 (rank : 57)	NC score	0.506674 (rank : 64)
Query Neighborhood Hits	1371	Target Neighborhood Hits	172	Shared Neighborhood Hits	143
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

FARP1_HUMAN
θ value	8.38298e-14 (rank : 58)	NC score	0.274873 (rank : 625)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

EHD3_MOUSE
θ value	1.09485e-13 (rank : 59)	NC score	0.252122 (rank : 689)
Query Neighborhood Hits	1371	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXY6	Gene names	Ehd3, Ehd2
Domain Architecture
Description	EH-domain-containing protein 3.

ARHGF_HUMAN
θ value	1.86753e-13 (rank : 60)	NC score	0.430368 (rank : 269)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	85
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

NCF1_MOUSE
θ value	1.86753e-13 (rank : 61)	NC score	0.444332 (rank : 228)
Query Neighborhood Hits	1371	Target Neighborhood Hits	198	Shared Neighborhood Hits	183
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

CP135_MOUSE
θ value	2.43908e-13 (rank : 62)	NC score	0.516596 (rank : 29)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1278	Shared Neighborhood Hits	718
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

FGD4_MOUSE
θ value	2.43908e-13 (rank : 63)	NC score	0.415212 (rank : 314)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	111
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD3_HUMAN
θ value	3.18553e-13 (rank : 64)	NC score	0.400894 (rank : 354)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	88
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

EHD3_HUMAN
θ value	4.16044e-13 (rank : 65)	NC score	0.251607 (rank : 690)
Query Neighborhood Hits	1371	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZN3, Q8N514, Q9NZB3	Gene names	EHD3, EHD2
Domain Architecture
Description	EH-domain-containing protein 3.

GNRP_HUMAN
θ value	4.16044e-13 (rank : 66)	NC score	0.321015 (rank : 518)
Query Neighborhood Hits	1371	Target Neighborhood Hits	239	Shared Neighborhood Hits	121
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

CP250_HUMAN
θ value	5.43371e-13 (rank : 67)	NC score	0.523438 (rank : 21)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1805	Shared Neighborhood Hits	825
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DNMBP_HUMAN
θ value	5.43371e-13 (rank : 68)	NC score	0.577536 (rank : 7)
Query Neighborhood Hits	1371	Target Neighborhood Hits	413	Shared Neighborhood Hits	312
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FGD2_HUMAN
θ value	7.09661e-13 (rank : 69)	NC score	0.407133 (rank : 333)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

GNRP_MOUSE
θ value	7.09661e-13 (rank : 70)	NC score	0.331152 (rank : 502)
Query Neighborhood Hits	1371	Target Neighborhood Hits	191	Shared Neighborhood Hits	92
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

MY18A_HUMAN
θ value	7.09661e-13 (rank : 71)	NC score	0.475696 (rank : 155)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1929	Shared Neighborhood Hits	841
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

EHD4_MOUSE
θ value	9.26847e-13 (rank : 72)	NC score	0.253263 (rank : 686)
Query Neighborhood Hits	1371	Target Neighborhood Hits	40	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQP2	Gene names	Ehd4, Past2
Domain Architecture
Description	EH-domain-containing protein 4 (mPAST2).

FGD3_MOUSE
θ value	9.26847e-13 (rank : 73)	NC score	0.418458 (rank : 303)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	96
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

CCD46_HUMAN
θ value	1.2105e-12 (rank : 74)	NC score	0.525756 (rank : 19)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1430	Shared Neighborhood Hits	763
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

ANR26_HUMAN
θ value	1.58096e-12 (rank : 75)	NC score	0.447251 (rank : 220)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1614	Shared Neighborhood Hits	737
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

FGD2_MOUSE
θ value	2.0648e-12 (rank : 76)	NC score	0.406314 (rank : 337)
Query Neighborhood Hits	1371	Target Neighborhood Hits	163	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

GRAP_HUMAN
θ value	2.0648e-12 (rank : 77)	NC score	0.421585 (rank : 294)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	231
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

VAV2_HUMAN
θ value	2.69671e-12 (rank : 78)	NC score	0.507981 (rank : 61)
Query Neighborhood Hits	1371	Target Neighborhood Hits	453	Shared Neighborhood Hits	287
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	2.69671e-12 (rank : 79)	NC score	0.504947 (rank : 71)
Query Neighborhood Hits	1371	Target Neighborhood Hits	456	Shared Neighborhood Hits	283
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

DUET_HUMAN
θ value	3.52202e-12 (rank : 80)	NC score	0.164869 (rank : 1012)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1220	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

LBC_HUMAN
θ value	3.52202e-12 (rank : 81)	NC score	0.425218 (rank : 282)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	72
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

REPS2_MOUSE
θ value	3.52202e-12 (rank : 82)	NC score	0.284351 (rank : 596)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

VAV_MOUSE
θ value	3.52202e-12 (rank : 83)	NC score	0.517079 (rank : 28)
Query Neighborhood Hits	1371	Target Neighborhood Hits	430	Shared Neighborhood Hits	291
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

FARP2_MOUSE
θ value	4.59992e-12 (rank : 84)	NC score	0.297919 (rank : 571)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	95
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GRAP_MOUSE
θ value	6.00763e-12 (rank : 85)	NC score	0.423109 (rank : 290)
Query Neighborhood Hits	1371	Target Neighborhood Hits	309	Shared Neighborhood Hits	230
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	7.84624e-12 (rank : 86)	NC score	0.432821 (rank : 259)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	231
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	7.84624e-12 (rank : 87)	NC score	0.432512 (rank : 261)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	231
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

CCD41_MOUSE
θ value	1.02475e-11 (rank : 88)	NC score	0.516339 (rank : 30)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1399	Shared Neighborhood Hits	738
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

RB6I2_MOUSE
θ value	1.02475e-11 (rank : 89)	NC score	0.514739 (rank : 34)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1433	Shared Neighborhood Hits	762
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

STAM1_MOUSE
θ value	1.02475e-11 (rank : 90)	NC score	0.409097 (rank : 327)
Query Neighborhood Hits	1371	Target Neighborhood Hits	273	Shared Neighborhood Hits	217
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CENPE_HUMAN
θ value	1.33837e-11 (rank : 91)	NC score	0.472535 (rank : 164)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2060	Shared Neighborhood Hits	861
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

FARP2_HUMAN
θ value	1.33837e-11 (rank : 92)	NC score	0.279506 (rank : 610)
Query Neighborhood Hits	1371	Target Neighborhood Hits	240	Shared Neighborhood Hits	88
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MY18A_MOUSE
θ value	1.74796e-11 (rank : 93)	NC score	0.470172 (rank : 167)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1989	Shared Neighborhood Hits	843
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NCF1_HUMAN
θ value	1.74796e-11 (rank : 94)	NC score	0.440681 (rank : 236)
Query Neighborhood Hits	1371	Target Neighborhood Hits	198	Shared Neighborhood Hits	178
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

VAV_HUMAN
θ value	1.74796e-11 (rank : 95)	NC score	0.512275 (rank : 41)
Query Neighborhood Hits	1371	Target Neighborhood Hits	452	Shared Neighborhood Hits	292
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

CP135_HUMAN
θ value	2.98157e-11 (rank : 96)	NC score	0.511165 (rank : 48)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1290	Shared Neighborhood Hits	703
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

REPS1_HUMAN
θ value	2.98157e-11 (rank : 97)	NC score	0.274192 (rank : 626)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	69
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REPS1_MOUSE
θ value	2.98157e-11 (rank : 98)	NC score	0.275285 (rank : 624)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	70
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

IFT81_MOUSE
θ value	5.08577e-11 (rank : 99)	NC score	0.504704 (rank : 74)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	619
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

ABI2_HUMAN
θ value	6.64225e-11 (rank : 100)	NC score	0.420065 (rank : 300)
Query Neighborhood Hits	1371	Target Neighborhood Hits	350	Shared Neighborhood Hits	210
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	6.64225e-11 (rank : 101)	NC score	0.423948 (rank : 285)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	204
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

FGD1_HUMAN
θ value	8.67504e-11 (rank : 102)	NC score	0.381377 (rank : 403)
Query Neighborhood Hits	1371	Target Neighborhood Hits	367	Shared Neighborhood Hits	114
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

GOGA5_MOUSE
θ value	8.67504e-11 (rank : 103)	NC score	0.503334 (rank : 75)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1434	Shared Neighborhood Hits	739
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

STAM1_HUMAN
θ value	8.67504e-11 (rank : 104)	NC score	0.407386 (rank : 331)
Query Neighborhood Hits	1371	Target Neighborhood Hits	271	Shared Neighborhood Hits	223
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
θ value	8.67504e-11 (rank : 105)	NC score	0.404139 (rank : 345)
Query Neighborhood Hits	1371	Target Neighborhood Hits	285	Shared Neighborhood Hits	224
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

ERC2_HUMAN
θ value	1.133e-10 (rank : 106)	NC score	0.505445 (rank : 68)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1156	Shared Neighborhood Hits	686
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	1.133e-10 (rank : 107)	NC score	0.509716 (rank : 55)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1166	Shared Neighborhood Hits	697
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

FGD1_MOUSE
θ value	1.133e-10 (rank : 108)	NC score	0.380571 (rank : 405)
Query Neighborhood Hits	1371	Target Neighborhood Hits	387	Shared Neighborhood Hits	106
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

REST_HUMAN
θ value	1.133e-10 (rank : 109)	NC score	0.509504 (rank : 57)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1605	Shared Neighborhood Hits	794
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

PKHG1_HUMAN
θ value	2.52405e-10 (rank : 110)	NC score	0.434503 (rank : 254)
Query Neighborhood Hits	1371	Target Neighborhood Hits	174	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

RAD50_MOUSE
θ value	2.52405e-10 (rank : 111)	NC score	0.512016 (rank : 44)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1366	Shared Neighborhood Hits	716
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SRBS1_HUMAN
θ value	2.52405e-10 (rank : 112)	NC score	0.443245 (rank : 230)
Query Neighborhood Hits	1371	Target Neighborhood Hits	396	Shared Neighborhood Hits	250
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

BCR_HUMAN
θ value	3.29651e-10 (rank : 113)	NC score	0.278608 (rank : 614)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	99
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CENPF_HUMAN
θ value	3.29651e-10 (rank : 114)	NC score	0.518931 (rank : 25)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1932	Shared Neighborhood Hits	832
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CI039_HUMAN
θ value	5.62301e-10 (rank : 115)	NC score	0.507384 (rank : 63)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1171	Shared Neighborhood Hits	668
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

EHD4_HUMAN
θ value	1.25267e-09 (rank : 116)	NC score	0.246387 (rank : 706)
Query Neighborhood Hits	1371	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H223, Q9HAR1, Q9NZN2	Gene names	EHD4, HCA10, HCA11
Domain Architecture
Description	EH-domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11).

TPR_HUMAN
θ value	1.25267e-09 (rank : 117)	NC score	0.501067 (rank : 82)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1921	Shared Neighborhood Hits	822
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ABI1_HUMAN
θ value	1.63604e-09 (rank : 118)	NC score	0.393961 (rank : 374)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	185
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	1.63604e-09 (rank : 119)	NC score	0.407600 (rank : 330)
Query Neighborhood Hits	1371	Target Neighborhood Hits	246	Shared Neighborhood Hits	189
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

CK5P2_HUMAN
θ value	1.63604e-09 (rank : 120)	NC score	0.493623 (rank : 102)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1433	Shared Neighborhood Hits	754
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

GCC2_MOUSE
θ value	2.13673e-09 (rank : 121)	NC score	0.498796 (rank : 87)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1619	Shared Neighborhood Hits	786
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

VAV3_HUMAN
θ value	2.13673e-09 (rank : 122)	NC score	0.475355 (rank : 156)
Query Neighborhood Hits	1371	Target Neighborhood Hits	398	Shared Neighborhood Hits	258
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	2.13673e-09 (rank : 123)	NC score	0.473186 (rank : 161)
Query Neighborhood Hits	1371	Target Neighborhood Hits	404	Shared Neighborhood Hits	265
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ECT2_MOUSE
θ value	2.79066e-09 (rank : 124)	NC score	0.436658 (rank : 245)
Query Neighborhood Hits	1371	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FA62A_MOUSE
θ value	2.79066e-09 (rank : 125)	NC score	0.229511 (rank : 755)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	92
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FGR_HUMAN
θ value	2.79066e-09 (rank : 126)	NC score	0.160746 (rank : 1032)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1067	Shared Neighborhood Hits	258
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FYN_HUMAN
θ value	2.79066e-09 (rank : 127)	NC score	0.160042 (rank : 1038)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1078	Shared Neighborhood Hits	268
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	2.79066e-09 (rank : 128)	NC score	0.161678 (rank : 1026)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1073	Shared Neighborhood Hits	267
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

MRCKB_HUMAN
θ value	2.79066e-09 (rank : 129)	NC score	0.296543 (rank : 575)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2239	Shared Neighborhood Hits	815
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

TAXB1_HUMAN
θ value	2.79066e-09 (rank : 130)	NC score	0.499518 (rank : 86)
Query Neighborhood Hits	1371	Target Neighborhood Hits	829	Shared Neighborhood Hits	559
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

CCD41_HUMAN
θ value	3.64472e-09 (rank : 131)	NC score	0.514281 (rank : 36)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1139	Shared Neighborhood Hits	655
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

MRCKB_MOUSE
θ value	6.21693e-09 (rank : 132)	NC score	0.291484 (rank : 582)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2180	Shared Neighborhood Hits	799
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PLCG1_MOUSE
θ value	8.11959e-09 (rank : 133)	NC score	0.317583 (rank : 528)
Query Neighborhood Hits	1371	Target Neighborhood Hits	314	Shared Neighborhood Hits	206
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

STAM2_HUMAN
θ value	8.11959e-09 (rank : 134)	NC score	0.397969 (rank : 364)
Query Neighborhood Hits	1371	Target Neighborhood Hits	288	Shared Neighborhood Hits	232
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

EEA1_HUMAN
θ value	1.06045e-08 (rank : 135)	NC score	0.521225 (rank : 22)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1796	Shared Neighborhood Hits	814
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FA62A_HUMAN
θ value	1.06045e-08 (rank : 136)	NC score	0.230505 (rank : 751)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

GOGB1_HUMAN
θ value	1.06045e-08 (rank : 137)	NC score	0.510618 (rank : 52)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2297	Shared Neighborhood Hits	876
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SRC_HUMAN
θ value	1.06045e-08 (rank : 138)	NC score	0.155773 (rank : 1071)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1058	Shared Neighborhood Hits	265
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

GOGA4_MOUSE
θ value	1.38499e-08 (rank : 139)	NC score	0.510226 (rank : 53)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1939	Shared Neighborhood Hits	852
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HAPIP_HUMAN
θ value	1.38499e-08 (rank : 140)	NC score	0.430379 (rank : 268)
Query Neighborhood Hits	1371	Target Neighborhood Hits	350	Shared Neighborhood Hits	250
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

PIBF1_HUMAN
θ value	1.38499e-08 (rank : 141)	NC score	0.520481 (rank : 24)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1041	Shared Neighborhood Hits	654
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

RASL2_HUMAN
θ value	1.38499e-08 (rank : 142)	NC score	0.201362 (rank : 840)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	97
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RRBP1_MOUSE
θ value	1.38499e-08 (rank : 143)	NC score	0.433936 (rank : 256)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1650	Shared Neighborhood Hits	718
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

STAC3_HUMAN
θ value	1.38499e-08 (rank : 144)	NC score	0.373748 (rank : 414)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	174
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STK10_HUMAN
θ value	1.38499e-08 (rank : 145)	NC score	0.215934 (rank : 801)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1921	Shared Neighborhood Hits	699
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

DESP_HUMAN
θ value	1.80886e-08 (rank : 146)	NC score	0.497408 (rank : 91)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1470	Shared Neighborhood Hits	774
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

ROCK1_HUMAN
θ value	1.80886e-08 (rank : 147)	NC score	0.285981 (rank : 592)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2000	Shared Neighborhood Hits	748
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

BRE1B_HUMAN
θ value	2.36244e-08 (rank : 148)	NC score	0.443518 (rank : 229)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1040	Shared Neighborhood Hits	576
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CP250_MOUSE
θ value	2.36244e-08 (rank : 149)	NC score	0.515038 (rank : 33)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1583	Shared Neighborhood Hits	771
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CYLN2_MOUSE
θ value	2.36244e-08 (rank : 150)	NC score	0.479395 (rank : 146)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1002	Shared Neighborhood Hits	628
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

ECT2_HUMAN
θ value	2.36244e-08 (rank : 151)	NC score	0.426057 (rank : 277)
Query Neighborhood Hits	1371	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

GRAP2_MOUSE
θ value	2.36244e-08 (rank : 152)	NC score	0.414548 (rank : 317)
Query Neighborhood Hits	1371	Target Neighborhood Hits	297	Shared Neighborhood Hits	221
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

ROCK1_MOUSE
θ value	2.36244e-08 (rank : 153)	NC score	0.301142 (rank : 561)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2126	Shared Neighborhood Hits	799
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SM1L2_HUMAN
θ value	2.36244e-08 (rank : 154)	NC score	0.478641 (rank : 149)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1019	Shared Neighborhood Hits	649
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

AHI1_HUMAN
θ value	3.08544e-08 (rank : 155)	NC score	0.309279 (rank : 543)
Query Neighborhood Hits	1371	Target Neighborhood Hits	537	Shared Neighborhood Hits	242
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CI093_HUMAN
θ value	3.08544e-08 (rank : 156)	NC score	0.514039 (rank : 37)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1088	Shared Neighborhood Hits	665
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

MYO5C_HUMAN
θ value	3.08544e-08 (rank : 157)	NC score	0.393859 (rank : 375)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1206	Shared Neighborhood Hits	691
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

STAC3_MOUSE
θ value	3.08544e-08 (rank : 158)	NC score	0.377438 (rank : 411)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	180
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CUTL1_MOUSE
θ value	4.0297e-08 (rank : 159)	NC score	0.435849 (rank : 247)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1620	Shared Neighborhood Hits	678
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CYLN2_HUMAN
θ value	4.0297e-08 (rank : 160)	NC score	0.484153 (rank : 126)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1004	Shared Neighborhood Hits	627
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

GOGA4_HUMAN
θ value	4.0297e-08 (rank : 161)	NC score	0.518495 (rank : 26)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2034	Shared Neighborhood Hits	863
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA5_HUMAN
θ value	4.0297e-08 (rank : 162)	NC score	0.500472 (rank : 85)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1168	Shared Neighborhood Hits	679
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GRAP1_MOUSE
θ value	4.0297e-08 (rank : 163)	NC score	0.512623 (rank : 39)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1234	Shared Neighborhood Hits	723
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

AHI1_MOUSE
θ value	5.26297e-08 (rank : 164)	NC score	0.299756 (rank : 564)
Query Neighborhood Hits	1371	Target Neighborhood Hits	496	Shared Neighborhood Hits	220
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

BPAEA_MOUSE
θ value	5.26297e-08 (rank : 165)	NC score	0.481007 (rank : 140)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1480	Shared Neighborhood Hits	757
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CUTL1_HUMAN
θ value	5.26297e-08 (rank : 166)	NC score	0.435273 (rank : 250)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1574	Shared Neighborhood Hits	684
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GRAP2_HUMAN
θ value	5.26297e-08 (rank : 167)	NC score	0.410815 (rank : 324)
Query Neighborhood Hits	1371	Target Neighborhood Hits	304	Shared Neighborhood Hits	226
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

PLCG1_HUMAN
θ value	5.26297e-08 (rank : 168)	NC score	0.307525 (rank : 546)
Query Neighborhood Hits	1371	Target Neighborhood Hits	293	Shared Neighborhood Hits	197
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

TRIO_HUMAN
θ value	5.26297e-08 (rank : 169)	NC score	0.229548 (rank : 754)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1580	Shared Neighborhood Hits	447
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

CE290_HUMAN
θ value	6.87365e-08 (rank : 170)	NC score	0.512143 (rank : 43)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1553	Shared Neighborhood Hits	776
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MYH3_HUMAN
θ value	6.87365e-08 (rank : 171)	NC score	0.428704 (rank : 273)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1660	Shared Neighborhood Hits	814
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYOF_HUMAN
θ value	6.87365e-08 (rank : 172)	NC score	0.187213 (rank : 888)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

RAD50_HUMAN
θ value	6.87365e-08 (rank : 173)	NC score	0.504893 (rank : 73)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1317	Shared Neighborhood Hits	692
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

GAS8_HUMAN
θ value	8.97725e-08 (rank : 174)	NC score	0.502449 (rank : 77)
Query Neighborhood Hits	1371	Target Neighborhood Hits	819	Shared Neighborhood Hits	585
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GOGA3_MOUSE
θ value	8.97725e-08 (rank : 175)	NC score	0.510723 (rank : 51)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1437	Shared Neighborhood Hits	756
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CCD96_HUMAN
θ value	1.17247e-07 (rank : 176)	NC score	0.403933 (rank : 346)
Query Neighborhood Hits	1371	Target Neighborhood Hits	595	Shared Neighborhood Hits	372
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

HCLS1_MOUSE
θ value	1.17247e-07 (rank : 177)	NC score	0.403431 (rank : 347)
Query Neighborhood Hits	1371	Target Neighborhood Hits	329	Shared Neighborhood Hits	198
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

M3KL4_HUMAN
θ value	1.17247e-07 (rank : 178)	NC score	0.156312 (rank : 1063)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1087	Shared Neighborhood Hits	323
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

RB6I2_HUMAN
θ value	1.17247e-07 (rank : 179)	NC score	0.514323 (rank : 35)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1584	Shared Neighborhood Hits	788
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SH3G2_HUMAN
θ value	1.53129e-07 (rank : 180)	NC score	0.402978 (rank : 348)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	291
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

TAOK1_HUMAN
θ value	1.53129e-07 (rank : 181)	NC score	0.210299 (rank : 819)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1734	Shared Neighborhood Hits	638
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

HOOK3_MOUSE
θ value	1.99992e-07 (rank : 182)	NC score	0.486234 (rank : 121)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1007	Shared Neighborhood Hits	631
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

LIPA2_MOUSE
θ value	1.99992e-07 (rank : 183)	NC score	0.452903 (rank : 198)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1282	Shared Neighborhood Hits	723
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MCF2L_MOUSE
θ value	1.99992e-07 (rank : 184)	NC score	0.420114 (rank : 299)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	188
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

SYCP1_HUMAN
θ value	1.99992e-07 (rank : 185)	NC score	0.508456 (rank : 60)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1313	Shared Neighborhood Hits	728
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TAOK1_MOUSE
θ value	1.99992e-07 (rank : 186)	NC score	0.210042 (rank : 821)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1720	Shared Neighborhood Hits	636
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

YES_MOUSE
θ value	1.99992e-07 (rank : 187)	NC score	0.157516 (rank : 1058)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1052	Shared Neighborhood Hits	262
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

FGR_MOUSE
θ value	2.61198e-07 (rank : 188)	NC score	0.154384 (rank : 1076)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1069	Shared Neighborhood Hits	260
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

HCLS1_HUMAN
θ value	2.61198e-07 (rank : 189)	NC score	0.400861 (rank : 356)
Query Neighborhood Hits	1371	Target Neighborhood Hits	358	Shared Neighborhood Hits	203
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HOOK3_HUMAN
θ value	2.61198e-07 (rank : 190)	NC score	0.488352 (rank : 114)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1070	Shared Neighborhood Hits	650
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

KIF4A_HUMAN
θ value	2.61198e-07 (rank : 191)	NC score	0.387022 (rank : 390)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1159	Shared Neighborhood Hits	663
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

CASP_HUMAN
θ value	3.41135e-07 (rank : 192)	NC score	0.479194 (rank : 148)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1131	Shared Neighborhood Hits	670
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

HMMR_MOUSE
θ value	3.41135e-07 (rank : 193)	NC score	0.512212 (rank : 42)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1178	Shared Neighborhood Hits	679
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

KIF14_HUMAN
θ value	3.41135e-07 (rank : 194)	NC score	0.256127 (rank : 672)
Query Neighborhood Hits	1371	Target Neighborhood Hits	732	Shared Neighborhood Hits	498
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

MYH2_HUMAN
θ value	3.41135e-07 (rank : 195)	NC score	0.415962 (rank : 310)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1491	Shared Neighborhood Hits	766
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

NIN_MOUSE
θ value	3.41135e-07 (rank : 196)	NC score	0.497405 (rank : 92)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1376	Shared Neighborhood Hits	727
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

FLIP1_HUMAN
θ value	4.45536e-07 (rank : 197)	NC score	0.508801 (rank : 59)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1405	Shared Neighborhood Hits	757
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GCC2_HUMAN
θ value	4.45536e-07 (rank : 198)	NC score	0.495621 (rank : 97)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1558	Shared Neighborhood Hits	748
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

MYO1E_HUMAN
θ value	4.45536e-07 (rank : 199)	NC score	0.275337 (rank : 623)
Query Neighborhood Hits	1371	Target Neighborhood Hits	293	Shared Neighborhood Hits	234
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	4.45536e-07 (rank : 200)	NC score	0.277249 (rank : 617)
Query Neighborhood Hits	1371	Target Neighborhood Hits	275	Shared Neighborhood Hits	231
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	4.45536e-07 (rank : 201)	NC score	0.276610 (rank : 619)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	229
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NIN_HUMAN
θ value	4.45536e-07 (rank : 202)	NC score	0.501016 (rank : 83)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1416	Shared Neighborhood Hits	741
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RBP24_HUMAN
θ value	4.45536e-07 (rank : 203)	NC score	0.495879 (rank : 96)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1559	Shared Neighborhood Hits	749
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

ROCK2_HUMAN
θ value	4.45536e-07 (rank : 204)	NC score	0.280698 (rank : 607)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2073	Shared Neighborhood Hits	761
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SRC8_MOUSE
θ value	4.45536e-07 (rank : 205)	NC score	0.400526 (rank : 357)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	210
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

TAXB1_MOUSE
θ value	4.45536e-07 (rank : 206)	NC score	0.489531 (rank : 110)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	577
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

YES_HUMAN
θ value	4.45536e-07 (rank : 207)	NC score	0.156116 (rank : 1067)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1059	Shared Neighborhood Hits	261
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ANM2_HUMAN
θ value	5.81887e-07 (rank : 208)	NC score	0.250756 (rank : 695)
Query Neighborhood Hits	1371	Target Neighborhood Hits	175	Shared Neighborhood Hits	157
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANR26_MOUSE
θ value	5.81887e-07 (rank : 209)	NC score	0.442607 (rank : 231)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1554	Shared Neighborhood Hits	722
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MCF2_HUMAN
θ value	5.81887e-07 (rank : 210)	NC score	0.398219 (rank : 362)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	137
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MYH6_MOUSE
θ value	5.81887e-07 (rank : 211)	NC score	0.416237 (rank : 308)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1501	Shared Neighborhood Hits	766
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

OSTF1_HUMAN
θ value	5.81887e-07 (rank : 212)	NC score	0.338066 (rank : 486)
Query Neighborhood Hits	1371	Target Neighborhood Hits	466	Shared Neighborhood Hits	229
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

SH3G2_MOUSE
θ value	5.81887e-07 (rank : 213)	NC score	0.397396 (rank : 365)
Query Neighborhood Hits	1371	Target Neighborhood Hits	319	Shared Neighborhood Hits	284
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SRC8_HUMAN
θ value	5.81887e-07 (rank : 214)	NC score	0.404344 (rank : 344)
Query Neighborhood Hits	1371	Target Neighborhood Hits	269	Shared Neighborhood Hits	215
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

AZI1_HUMAN
θ value	7.59969e-07 (rank : 215)	NC score	0.501864 (rank : 79)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1000	Shared Neighborhood Hits	626
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CASP_MOUSE
θ value	7.59969e-07 (rank : 216)	NC score	0.481878 (rank : 137)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1152	Shared Neighborhood Hits	675
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

DOC2B_HUMAN
θ value	7.59969e-07 (rank : 217)	NC score	0.197177 (rank : 851)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	88
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
θ value	7.59969e-07 (rank : 218)	NC score	0.197422 (rank : 849)
Query Neighborhood Hits	1371	Target Neighborhood Hits	169	Shared Neighborhood Hits	91
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

LYN_MOUSE
θ value	7.59969e-07 (rank : 219)	NC score	0.133696 (rank : 1204)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1023	Shared Neighborhood Hits	227
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

WDR67_HUMAN
θ value	7.59969e-07 (rank : 220)	NC score	0.360540 (rank : 443)
Query Neighborhood Hits	1371	Target Neighborhood Hits	782	Shared Neighborhood Hits	460
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

ANM2_MOUSE
θ value	9.92553e-07 (rank : 221)	NC score	0.241348 (rank : 724)
Query Neighborhood Hits	1371	Target Neighborhood Hits	175	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

HMMR_HUMAN
θ value	9.92553e-07 (rank : 222)	NC score	0.511600 (rank : 47)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1082	Shared Neighborhood Hits	653
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

LYN_HUMAN
θ value	9.92553e-07 (rank : 223)	NC score	0.134850 (rank : 1193)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1022	Shared Neighborhood Hits	226
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MRCKA_HUMAN
θ value	9.92553e-07 (rank : 224)	NC score	0.272045 (rank : 633)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1999	Shared Neighborhood Hits	774
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

NCF2_HUMAN
θ value	9.92553e-07 (rank : 225)	NC score	0.453293 (rank : 197)
Query Neighborhood Hits	1371	Target Neighborhood Hits	229	Shared Neighborhood Hits	188
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NPHP1_HUMAN
θ value	9.92553e-07 (rank : 226)	NC score	0.347897 (rank : 472)
Query Neighborhood Hits	1371	Target Neighborhood Hits	288	Shared Neighborhood Hits	235
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

OPTN_MOUSE
θ value	9.92553e-07 (rank : 227)	NC score	0.487981 (rank : 117)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1120	Shared Neighborhood Hits	652
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RHG04_HUMAN
θ value	9.92553e-07 (rank : 228)	NC score	0.263773 (rank : 650)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	217
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SH3G3_MOUSE
θ value	9.92553e-07 (rank : 229)	NC score	0.390899 (rank : 382)
Query Neighborhood Hits	1371	Target Neighborhood Hits	236	Shared Neighborhood Hits	220
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

CING_MOUSE
θ value	1.29631e-06 (rank : 230)	NC score	0.505063 (rank : 70)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1432	Shared Neighborhood Hits	750
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

M3K11_HUMAN
θ value	1.29631e-06 (rank : 231)	NC score	0.143374 (rank : 1141)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1136	Shared Neighborhood Hits	275
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

NOXO1_MOUSE
θ value	1.29631e-06 (rank : 232)	NC score	0.304600 (rank : 550)
Query Neighborhood Hits	1371	Target Neighborhood Hits	114	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

OSTF1_MOUSE
θ value	1.29631e-06 (rank : 233)	NC score	0.327806 (rank : 504)
Query Neighborhood Hits	1371	Target Neighborhood Hits	467	Shared Neighborhood Hits	228
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PCNT_HUMAN
θ value	1.29631e-06 (rank : 234)	NC score	0.497718 (rank : 89)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1551	Shared Neighborhood Hits	763
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RBCC1_MOUSE
θ value	1.29631e-06 (rank : 235)	NC score	0.487078 (rank : 118)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1048	Shared Neighborhood Hits	644
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

ROCK2_MOUSE
θ value	1.29631e-06 (rank : 236)	NC score	0.288180 (rank : 587)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2072	Shared Neighborhood Hits	782
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SRC_MOUSE
θ value	1.29631e-06 (rank : 237)	NC score	0.140483 (rank : 1157)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1033	Shared Neighborhood Hits	235
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRGP1_HUMAN
θ value	1.29631e-06 (rank : 238)	NC score	0.264237 (rank : 648)
Query Neighborhood Hits	1371	Target Neighborhood Hits	390	Shared Neighborhood Hits	275
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

LZTS1_MOUSE
θ value	1.69304e-06 (rank : 239)	NC score	0.406060 (rank : 338)
Query Neighborhood Hits	1371	Target Neighborhood Hits	540	Shared Neighborhood Hits	395
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

PCLO_HUMAN
θ value	1.69304e-06 (rank : 240)	NC score	0.250126 (rank : 696)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2046	Shared Neighborhood Hits	509
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RP3A_MOUSE
θ value	1.69304e-06 (rank : 241)	NC score	0.194187 (rank : 865)
Query Neighborhood Hits	1371	Target Neighborhood Hits	510	Shared Neighborhood Hits	116
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SMC2_HUMAN
θ value	1.69304e-06 (rank : 242)	NC score	0.483776 (rank : 128)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1405	Shared Neighborhood Hits	756
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SRGP2_HUMAN
θ value	1.69304e-06 (rank : 243)	NC score	0.247535 (rank : 703)
Query Neighborhood Hits	1371	Target Neighborhood Hits	331	Shared Neighborhood Hits	226
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

BTK_MOUSE
θ value	2.21117e-06 (rank : 244)	NC score	0.142300 (rank : 1148)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1017	Shared Neighborhood Hits	245
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CEP63_HUMAN
θ value	2.21117e-06 (rank : 245)	NC score	0.515697 (rank : 31)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1005	Shared Neighborhood Hits	633
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

GOGA1_MOUSE
θ value	2.21117e-06 (rank : 246)	NC score	0.505536 (rank : 67)
Query Neighborhood Hits	1371	Target Neighborhood Hits	994	Shared Neighborhood Hits	624
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

M3K9_HUMAN
θ value	2.21117e-06 (rank : 247)	NC score	0.142824 (rank : 1144)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1123	Shared Neighborhood Hits	293
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MYH11_HUMAN
θ value	2.21117e-06 (rank : 248)	NC score	0.434602 (rank : 253)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1806	Shared Neighborhood Hits	836
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH1_MOUSE
θ value	2.21117e-06 (rank : 249)	NC score	0.415367 (rank : 313)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1461	Shared Neighborhood Hits	763
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

NCF4_MOUSE
θ value	2.21117e-06 (rank : 250)	NC score	0.392491 (rank : 378)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	151
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NED4L_HUMAN
θ value	2.21117e-06 (rank : 251)	NC score	0.126032 (rank : 1264)
Query Neighborhood Hits	1371	Target Neighborhood Hits	238	Shared Neighborhood Hits	101
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	2.21117e-06 (rank : 252)	NC score	0.125771 (rank : 1266)
Query Neighborhood Hits	1371	Target Neighborhood Hits	231	Shared Neighborhood Hits	103
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SYT5_HUMAN
θ value	2.21117e-06 (rank : 253)	NC score	0.178900 (rank : 930)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	85
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

AKAP9_HUMAN
θ value	2.88788e-06 (rank : 254)	NC score	0.512443 (rank : 40)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1710	Shared Neighborhood Hits	802
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

BTK_HUMAN
θ value	2.88788e-06 (rank : 255)	NC score	0.145766 (rank : 1127)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1026	Shared Neighborhood Hits	256
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

CCD21_HUMAN
θ value	2.88788e-06 (rank : 256)	NC score	0.483952 (rank : 127)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1228	Shared Neighborhood Hits	670
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MD1L1_MOUSE
θ value	2.88788e-06 (rank : 257)	NC score	0.509029 (rank : 58)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1001	Shared Neighborhood Hits	627
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MYH8_HUMAN
θ value	2.88788e-06 (rank : 258)	NC score	0.423655 (rank : 287)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1610	Shared Neighborhood Hits	804
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NCF4_HUMAN
θ value	2.88788e-06 (rank : 259)	NC score	0.380975 (rank : 404)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	136
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

PEPL_HUMAN
θ value	2.88788e-06 (rank : 260)	NC score	0.482339 (rank : 134)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1141	Shared Neighborhood Hits	682
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PPIP1_MOUSE
θ value	2.88788e-06 (rank : 261)	NC score	0.435635 (rank : 248)
Query Neighborhood Hits	1371	Target Neighborhood Hits	377	Shared Neighborhood Hits	344
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SPTA2_HUMAN
θ value	2.88788e-06 (rank : 262)	NC score	0.427297 (rank : 276)
Query Neighborhood Hits	1371	Target Neighborhood Hits	888	Shared Neighborhood Hits	619
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SYCP1_MOUSE
θ value	2.88788e-06 (rank : 263)	NC score	0.511977 (rank : 45)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1456	Shared Neighborhood Hits	755
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYT2_HUMAN
θ value	2.88788e-06 (rank : 264)	NC score	0.174414 (rank : 958)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_MOUSE
θ value	2.88788e-06 (rank : 265)	NC score	0.174476 (rank : 957)
Query Neighborhood Hits	1371	Target Neighborhood Hits	143	Shared Neighborhood Hits	86
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

FNBP2_HUMAN
θ value	3.77169e-06 (rank : 266)	NC score	0.273312 (rank : 629)
Query Neighborhood Hits	1371	Target Neighborhood Hits	432	Shared Neighborhood Hits	293
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

KMHN1_HUMAN
θ value	3.77169e-06 (rank : 267)	NC score	0.484256 (rank : 125)
Query Neighborhood Hits	1371	Target Neighborhood Hits	950	Shared Neighborhood Hits	589
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

MYH8_MOUSE
θ value	3.77169e-06 (rank : 268)	NC score	0.421728 (rank : 293)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1600	Shared Neighborhood Hits	793
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PLCG2_HUMAN
θ value	3.77169e-06 (rank : 269)	NC score	0.300752 (rank : 563)
Query Neighborhood Hits	1371	Target Neighborhood Hits	280	Shared Neighborhood Hits	189
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PPIP1_HUMAN
θ value	3.77169e-06 (rank : 270)	NC score	0.448146 (rank : 212)
Query Neighborhood Hits	1371	Target Neighborhood Hits	389	Shared Neighborhood Hits	353
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SH3G1_MOUSE
θ value	3.77169e-06 (rank : 271)	NC score	0.386979 (rank : 391)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	261
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G3_HUMAN
θ value	3.77169e-06 (rank : 272)	NC score	0.374041 (rank : 413)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	205
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

TAOK3_HUMAN
θ value	3.77169e-06 (rank : 273)	NC score	0.184951 (rank : 901)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1494	Shared Neighborhood Hits	553
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

KINH_HUMAN
θ value	4.92598e-06 (rank : 274)	NC score	0.402372 (rank : 349)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1231	Shared Neighborhood Hits	705
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

REST_MOUSE
θ value	4.92598e-06 (rank : 275)	NC score	0.494245 (rank : 100)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1506	Shared Neighborhood Hits	740
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RRBP1_HUMAN
θ value	4.92598e-06 (rank : 276)	NC score	0.445928 (rank : 223)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1306	Shared Neighborhood Hits	646
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SMC1A_MOUSE
θ value	4.92598e-06 (rank : 277)	NC score	0.485854 (rank : 122)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1384	Shared Neighborhood Hits	767
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC3_HUMAN
θ value	4.92598e-06 (rank : 278)	NC score	0.482127 (rank : 135)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1186	Shared Neighborhood Hits	704
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	4.92598e-06 (rank : 279)	NC score	0.482522 (rank : 132)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1187	Shared Neighborhood Hits	705
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SRGP2_MOUSE
θ value	4.92598e-06 (rank : 280)	NC score	0.251515 (rank : 691)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	232
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SYT1_HUMAN
θ value	4.92598e-06 (rank : 281)	NC score	0.176052 (rank : 945)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	90
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	4.92598e-06 (rank : 282)	NC score	0.176039 (rank : 947)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	90
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

UACA_MOUSE
θ value	4.92598e-06 (rank : 283)	NC score	0.430545 (rank : 267)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1620	Shared Neighborhood Hits	743
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

CRKL_HUMAN
θ value	6.43352e-06 (rank : 284)	NC score	0.370146 (rank : 419)
Query Neighborhood Hits	1371	Target Neighborhood Hits	313	Shared Neighborhood Hits	221
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

GOGA1_HUMAN
θ value	6.43352e-06 (rank : 285)	NC score	0.504897 (rank : 72)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1222	Shared Neighborhood Hits	693
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PACN2_MOUSE
θ value	6.43352e-06 (rank : 286)	NC score	0.382550 (rank : 398)
Query Neighborhood Hits	1371	Target Neighborhood Hits	382	Shared Neighborhood Hits	311
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

CE152_HUMAN
θ value	8.40245e-06 (rank : 287)	NC score	0.497684 (rank : 90)
Query Neighborhood Hits	1371	Target Neighborhood Hits	976	Shared Neighborhood Hits	609
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CF060_HUMAN
θ value	8.40245e-06 (rank : 288)	NC score	0.511053 (rank : 49)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1270	Shared Neighborhood Hits	715
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CT2NL_HUMAN
θ value	8.40245e-06 (rank : 289)	NC score	0.455244 (rank : 192)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1059	Shared Neighborhood Hits	613
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

KTN1_MOUSE
θ value	8.40245e-06 (rank : 290)	NC score	0.501844 (rank : 80)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1324	Shared Neighborhood Hits	725
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYH7_HUMAN
θ value	8.40245e-06 (rank : 291)	NC score	0.415044 (rank : 315)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1559	Shared Neighborhood Hits	775
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NEBL_HUMAN
θ value	8.40245e-06 (rank : 292)	NC score	0.438100 (rank : 241)
Query Neighborhood Hits	1371	Target Neighborhood Hits	457	Shared Neighborhood Hits	370
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEDD4_HUMAN
θ value	8.40245e-06 (rank : 293)	NC score	0.120863 (rank : 1294)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	101
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

PCLO_MOUSE
θ value	8.40245e-06 (rank : 294)	NC score	0.218444 (rank : 793)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2275	Shared Neighborhood Hits	503
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RUFY2_HUMAN
θ value	8.40245e-06 (rank : 295)	NC score	0.472734 (rank : 163)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1208	Shared Neighborhood Hits	676
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SH3G1_HUMAN
θ value	8.40245e-06 (rank : 296)	NC score	0.391995 (rank : 380)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	279
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SM1L2_MOUSE
θ value	8.40245e-06 (rank : 297)	NC score	0.456722 (rank : 187)
Query Neighborhood Hits	1371	Target Neighborhood Hits	918	Shared Neighborhood Hits	588
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

BPA1_MOUSE
θ value	1.09739e-05 (rank : 298)	NC score	0.372155 (rank : 416)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1477	Shared Neighborhood Hits	685
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DDEF1_MOUSE
θ value	1.09739e-05 (rank : 299)	NC score	0.205303 (rank : 830)
Query Neighborhood Hits	1371	Target Neighborhood Hits	592	Shared Neighborhood Hits	221
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

GOGA6_HUMAN
θ value	1.09739e-05 (rank : 300)	NC score	0.501885 (rank : 78)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1007	Shared Neighborhood Hits	655
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

K0552_HUMAN
θ value	1.09739e-05 (rank : 301)	NC score	0.360984 (rank : 441)
Query Neighborhood Hits	1371	Target Neighborhood Hits	442	Shared Neighborhood Hits	328
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

OPTN_HUMAN
θ value	1.09739e-05 (rank : 302)	NC score	0.465359 (rank : 174)
Query Neighborhood Hits	1371	Target Neighborhood Hits	827	Shared Neighborhood Hits	552
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PACN2_HUMAN
θ value	1.09739e-05 (rank : 303)	NC score	0.378308 (rank : 408)
Query Neighborhood Hits	1371	Target Neighborhood Hits	339	Shared Neighborhood Hits	290
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

RAI14_MOUSE
θ value	1.09739e-05 (rank : 304)	NC score	0.375169 (rank : 412)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1505	Shared Neighborhood Hits	674
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SNX23_HUMAN
θ value	1.09739e-05 (rank : 305)	NC score	0.351971 (rank : 463)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	593
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

TAOK3_MOUSE
θ value	1.09739e-05 (rank : 306)	NC score	0.175494 (rank : 949)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1458	Shared Neighborhood Hits	539
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

TRHY_HUMAN
θ value	1.09739e-05 (rank : 307)	NC score	0.507718 (rank : 62)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1385	Shared Neighborhood Hits	722
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

BICD2_HUMAN
θ value	1.43324e-05 (rank : 308)	NC score	0.447556 (rank : 219)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	559
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CCD21_MOUSE
θ value	1.43324e-05 (rank : 309)	NC score	0.488291 (rank : 115)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1135	Shared Neighborhood Hits	651
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CN145_HUMAN
θ value	1.43324e-05 (rank : 310)	NC score	0.509528 (rank : 56)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1196	Shared Neighborhood Hits	705
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CTRO_MOUSE
θ value	1.43324e-05 (rank : 311)	NC score	0.312768 (rank : 538)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2344	Shared Neighborhood Hits	850
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DDEF2_MOUSE
θ value	1.43324e-05 (rank : 312)	NC score	0.195108 (rank : 861)
Query Neighborhood Hits	1371	Target Neighborhood Hits	625	Shared Neighborhood Hits	235
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

GOGA3_HUMAN
θ value	1.43324e-05 (rank : 313)	NC score	0.500584 (rank : 84)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1317	Shared Neighborhood Hits	718
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

HCK_MOUSE
θ value	1.43324e-05 (rank : 314)	NC score	0.140533 (rank : 1156)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1029	Shared Neighborhood Hits	243
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HOME2_MOUSE
θ value	1.43324e-05 (rank : 315)	NC score	0.410236 (rank : 325)
Query Neighborhood Hits	1371	Target Neighborhood Hits	882	Shared Neighborhood Hits	569
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

K0555_HUMAN
θ value	1.43324e-05 (rank : 316)	NC score	0.489238 (rank : 111)
Query Neighborhood Hits	1371	Target Neighborhood Hits	880	Shared Neighborhood Hits	572
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

MYH11_MOUSE
θ value	1.43324e-05 (rank : 317)	NC score	0.432131 (rank : 263)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1777	Shared Neighborhood Hits	829
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH1_HUMAN
θ value	1.43324e-05 (rank : 318)	NC score	0.416084 (rank : 309)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1478	Shared Neighborhood Hits	768
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

OTOF_HUMAN
θ value	1.43324e-05 (rank : 319)	NC score	0.168780 (rank : 990)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	1.43324e-05 (rank : 320)	NC score	0.170073 (rank : 983)
Query Neighborhood Hits	1371	Target Neighborhood Hits	196	Shared Neighborhood Hits	112
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

RP3A_HUMAN
θ value	1.43324e-05 (rank : 321)	NC score	0.193975 (rank : 867)
Query Neighborhood Hits	1371	Target Neighborhood Hits	305	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SMC4_MOUSE
θ value	1.43324e-05 (rank : 322)	NC score	0.425515 (rank : 279)
Query Neighborhood Hits	1371	Target Neighborhood Hits	830	Shared Neighborhood Hits	532
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SYT3_MOUSE
θ value	1.43324e-05 (rank : 323)	NC score	0.180001 (rank : 924)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

BI2L1_HUMAN
θ value	1.87187e-05 (rank : 324)	NC score	0.227023 (rank : 761)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BI2L1_MOUSE
θ value	1.87187e-05 (rank : 325)	NC score	0.200882 (rank : 842)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	124
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CCD39_HUMAN
θ value	1.87187e-05 (rank : 326)	NC score	0.492384 (rank : 104)
Query Neighborhood Hits	1371	Target Neighborhood Hits	868	Shared Neighborhood Hits	581
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	1.87187e-05 (rank : 327)	NC score	0.497300 (rank : 93)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1026	Shared Neighborhood Hits	640
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

DYSF_HUMAN
θ value	1.87187e-05 (rank : 328)	NC score	0.166742 (rank : 997)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	97
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

KI21A_HUMAN
θ value	1.87187e-05 (rank : 329)	NC score	0.332125 (rank : 500)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1543	Shared Neighborhood Hits	719
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

LZTS1_HUMAN
θ value	1.87187e-05 (rank : 330)	NC score	0.405177 (rank : 341)
Query Neighborhood Hits	1371	Target Neighborhood Hits	532	Shared Neighborhood Hits	397
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MYH9_HUMAN
θ value	1.87187e-05 (rank : 331)	NC score	0.430795 (rank : 265)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1762	Shared Neighborhood Hits	827
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NEDD4_MOUSE
θ value	1.87187e-05 (rank : 332)	NC score	0.116681 (rank : 1326)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	97
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

PA24D_MOUSE
θ value	1.87187e-05 (rank : 333)	NC score	0.159625 (rank : 1040)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PACN3_HUMAN
θ value	1.87187e-05 (rank : 334)	NC score	0.366289 (rank : 428)
Query Neighborhood Hits	1371	Target Neighborhood Hits	385	Shared Neighborhood Hits	314
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

RFIP3_HUMAN
θ value	1.87187e-05 (rank : 335)	NC score	0.460555 (rank : 182)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1055	Shared Neighborhood Hits	596
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RHG26_HUMAN
θ value	1.87187e-05 (rank : 336)	NC score	0.212836 (rank : 810)
Query Neighborhood Hits	1371	Target Neighborhood Hits	281	Shared Neighborhood Hits	184
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SYT3_HUMAN
θ value	1.87187e-05 (rank : 337)	NC score	0.179582 (rank : 927)
Query Neighborhood Hits	1371	Target Neighborhood Hits	145	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

TEC_MOUSE
θ value	1.87187e-05 (rank : 338)	NC score	0.123407 (rank : 1277)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1006	Shared Neighborhood Hits	215
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ABR_HUMAN
θ value	2.44474e-05 (rank : 339)	NC score	0.257028 (rank : 667)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	93
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

DDEF2_HUMAN
θ value	2.44474e-05 (rank : 340)	NC score	0.193909 (rank : 868)
Query Neighborhood Hits	1371	Target Neighborhood Hits	599	Shared Neighborhood Hits	234
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

HCK_HUMAN
θ value	2.44474e-05 (rank : 341)	NC score	0.140623 (rank : 1155)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1035	Shared Neighborhood Hits	244
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

KPCA_HUMAN
θ value	2.44474e-05 (rank : 342)	NC score	0.102503 (rank : 1440)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1070	Shared Neighborhood Hits	190
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

MYH9_MOUSE
θ value	2.44474e-05 (rank : 343)	NC score	0.429821 (rank : 271)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1829	Shared Neighborhood Hits	836
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NEBU_HUMAN
θ value	2.44474e-05 (rank : 344)	NC score	0.298352 (rank : 568)
Query Neighborhood Hits	1371	Target Neighborhood Hits	420	Shared Neighborhood Hits	290
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NUMA1_HUMAN
θ value	2.44474e-05 (rank : 345)	NC score	0.511840 (rank : 46)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1523	Shared Neighborhood Hits	761
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

TCRG1_HUMAN
θ value	2.44474e-05 (rank : 346)	NC score	0.323625 (rank : 512)
Query Neighborhood Hits	1371	Target Neighborhood Hits	929	Shared Neighborhood Hits	447
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	2.44474e-05 (rank : 347)	NC score	0.321295 (rank : 517)
Query Neighborhood Hits	1371	Target Neighborhood Hits	947	Shared Neighborhood Hits	445
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

CJ118_MOUSE
θ value	3.19293e-05 (rank : 348)	NC score	0.498365 (rank : 88)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1132	Shared Neighborhood Hits	675
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

DMD_HUMAN
θ value	3.19293e-05 (rank : 349)	NC score	0.372082 (rank : 417)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1135	Shared Neighborhood Hits	621
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

FGD5_HUMAN
θ value	3.19293e-05 (rank : 350)	NC score	0.248443 (rank : 700)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

HIP1_HUMAN
θ value	3.19293e-05 (rank : 351)	NC score	0.447197 (rank : 221)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1016	Shared Neighborhood Hits	614
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

MYH10_HUMAN
θ value	3.19293e-05 (rank : 352)	NC score	0.425485 (rank : 280)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1620	Shared Neighborhood Hits	810
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	3.19293e-05 (rank : 353)	NC score	0.425461 (rank : 281)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1612	Shared Neighborhood Hits	805
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SMC1A_HUMAN
θ value	3.19293e-05 (rank : 354)	NC score	0.479724 (rank : 144)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1346	Shared Neighborhood Hits	750
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

ABI3_HUMAN
θ value	4.1701e-05 (rank : 355)	NC score	0.355855 (rank : 454)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	151
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

IASPP_MOUSE
θ value	4.1701e-05 (rank : 356)	NC score	0.214795 (rank : 806)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1024	Shared Neighborhood Hits	236
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

K1H2_HUMAN
θ value	4.1701e-05 (rank : 357)	NC score	0.191101 (rank : 877)
Query Neighborhood Hits	1371	Target Neighborhood Hits	492	Shared Neighborhood Hits	343
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

KMHN1_MOUSE
θ value	4.1701e-05 (rank : 358)	NC score	0.489870 (rank : 109)
Query Neighborhood Hits	1371	Target Neighborhood Hits	949	Shared Neighborhood Hits	597
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

KPCB_HUMAN
θ value	4.1701e-05 (rank : 359)	NC score	0.102891 (rank : 1437)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1121	Shared Neighborhood Hits	187
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	4.1701e-05 (rank : 360)	NC score	0.103197 (rank : 1436)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1117	Shared Neighborhood Hits	187
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

LASP1_HUMAN
θ value	4.1701e-05 (rank : 361)	NC score	0.320146 (rank : 521)
Query Neighborhood Hits	1371	Target Neighborhood Hits	293	Shared Neighborhood Hits	172
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	4.1701e-05 (rank : 362)	NC score	0.318124 (rank : 525)
Query Neighborhood Hits	1371	Target Neighborhood Hits	297	Shared Neighborhood Hits	172
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MPP6_HUMAN
θ value	4.1701e-05 (rank : 363)	NC score	0.144281 (rank : 1135)
Query Neighborhood Hits	1371	Target Neighborhood Hits	180	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MYH6_HUMAN
θ value	4.1701e-05 (rank : 364)	NC score	0.414181 (rank : 318)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1426	Shared Neighborhood Hits	748
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PA24D_HUMAN
θ value	4.1701e-05 (rank : 365)	NC score	0.143005 (rank : 1142)
Query Neighborhood Hits	1371	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SAS6_MOUSE
θ value	4.1701e-05 (rank : 366)	NC score	0.482473 (rank : 133)
Query Neighborhood Hits	1371	Target Neighborhood Hits	931	Shared Neighborhood Hits	592
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SYNE1_HUMAN
θ value	4.1701e-05 (rank : 367)	NC score	0.407137 (rank : 332)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1484	Shared Neighborhood Hits	692
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TRIPB_HUMAN
θ value	4.1701e-05 (rank : 368)	NC score	0.514036 (rank : 38)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1587	Shared Neighborhood Hits	779
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CCD96_MOUSE
θ value	5.44631e-05 (rank : 369)	NC score	0.434729 (rank : 252)
Query Neighborhood Hits	1371	Target Neighborhood Hits	704	Shared Neighborhood Hits	454
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

DOC2A_MOUSE
θ value	5.44631e-05 (rank : 370)	NC score	0.192892 (rank : 870)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

FGD5_MOUSE
θ value	5.44631e-05 (rank : 371)	NC score	0.228954 (rank : 757)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	67
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

IASPP_HUMAN
θ value	5.44631e-05 (rank : 372)	NC score	0.231684 (rank : 750)
Query Neighborhood Hits	1371	Target Neighborhood Hits	688	Shared Neighborhood Hits	207
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF3A_MOUSE
θ value	5.44631e-05 (rank : 373)	NC score	0.467419 (rank : 170)
Query Neighborhood Hits	1371	Target Neighborhood Hits	871	Shared Neighborhood Hits	597
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

LIPA1_HUMAN
θ value	5.44631e-05 (rank : 374)	NC score	0.451336 (rank : 205)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1294	Shared Neighborhood Hits	718
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MPP6_MOUSE
θ value	5.44631e-05 (rank : 375)	NC score	0.140900 (rank : 1154)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

RABE1_HUMAN
θ value	5.44631e-05 (rank : 376)	NC score	0.482879 (rank : 130)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1104	Shared Neighborhood Hits	665
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

TEC_HUMAN
θ value	5.44631e-05 (rank : 377)	NC score	0.125411 (rank : 1267)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1006	Shared Neighborhood Hits	218
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ABI3_MOUSE
θ value	7.1131e-05 (rank : 378)	NC score	0.357846 (rank : 451)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

BCAR1_MOUSE
θ value	7.1131e-05 (rank : 379)	NC score	0.273268 (rank : 630)
Query Neighborhood Hits	1371	Target Neighborhood Hits	438	Shared Neighborhood Hits	191
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CRKL_MOUSE
θ value	7.1131e-05 (rank : 380)	NC score	0.363422 (rank : 437)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	218
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

DOC2A_HUMAN
θ value	7.1131e-05 (rank : 381)	NC score	0.192005 (rank : 873)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	89
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DYSF_MOUSE
θ value	7.1131e-05 (rank : 382)	NC score	0.161424 (rank : 1029)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

IF3A_HUMAN
θ value	7.1131e-05 (rank : 383)	NC score	0.463883 (rank : 177)
Query Neighborhood Hits	1371	Target Neighborhood Hits	875	Shared Neighborhood Hits	595
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

MYH4_MOUSE
θ value	7.1131e-05 (rank : 384)	NC score	0.411795 (rank : 322)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1476	Shared Neighborhood Hits	758
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

NOXO1_HUMAN
θ value	7.1131e-05 (rank : 385)	NC score	0.253913 (rank : 682)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

SDCG8_HUMAN
θ value	7.1131e-05 (rank : 386)	NC score	0.494727 (rank : 99)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1002	Shared Neighborhood Hits	636
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SYT5_MOUSE
θ value	7.1131e-05 (rank : 387)	NC score	0.173188 (rank : 964)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

KINH_MOUSE
θ value	9.29e-05 (rank : 388)	NC score	0.382838 (rank : 397)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1082	Shared Neighborhood Hits	663
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KPCA_MOUSE
θ value	9.29e-05 (rank : 389)	NC score	0.100664 (rank : 1458)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1067	Shared Neighborhood Hits	190
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

MD1L1_HUMAN
θ value	9.29e-05 (rank : 390)	NC score	0.493568 (rank : 103)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	584
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

PACN3_MOUSE
θ value	9.29e-05 (rank : 391)	NC score	0.364883 (rank : 433)
Query Neighborhood Hits	1371	Target Neighborhood Hits	380	Shared Neighborhood Hits	325
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PHLB2_MOUSE
θ value	9.29e-05 (rank : 392)	NC score	0.407687 (rank : 329)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1016	Shared Neighborhood Hits	601
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SMC4_HUMAN
θ value	9.29e-05 (rank : 393)	NC score	0.448139 (rank : 213)
Query Neighborhood Hits	1371	Target Neighborhood Hits	937	Shared Neighborhood Hits	596
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

EVPL_HUMAN
θ value	0.000121331 (rank : 394)	NC score	0.453665 (rank : 196)
Query Neighborhood Hits	1371	Target Neighborhood Hits	895	Shared Neighborhood Hits	580
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

HOOK1_HUMAN
θ value	0.000121331 (rank : 395)	NC score	0.476824 (rank : 151)
Query Neighborhood Hits	1371	Target Neighborhood Hits	942	Shared Neighborhood Hits	604
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

LMNB2_HUMAN
θ value	0.000121331 (rank : 396)	NC score	0.321007 (rank : 519)
Query Neighborhood Hits	1371	Target Neighborhood Hits	723	Shared Neighborhood Hits	507
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

LRC45_MOUSE
θ value	0.000121331 (rank : 397)	NC score	0.470682 (rank : 165)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	609
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

M3K10_HUMAN
θ value	0.000121331 (rank : 398)	NC score	0.132349 (rank : 1216)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1071	Shared Neighborhood Hits	280
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

PACN1_HUMAN
θ value	0.000121331 (rank : 399)	NC score	0.366788 (rank : 427)
Query Neighborhood Hits	1371	Target Neighborhood Hits	320	Shared Neighborhood Hits	287
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

POT15_HUMAN
θ value	0.000121331 (rank : 400)	NC score	0.158321 (rank : 1051)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	388
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

RBCC1_HUMAN
θ value	0.000121331 (rank : 401)	NC score	0.475968 (rank : 153)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1023	Shared Neighborhood Hits	611
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RFIP4_HUMAN
θ value	0.000121331 (rank : 402)	NC score	0.452163 (rank : 201)
Query Neighborhood Hits	1371	Target Neighborhood Hits	785	Shared Neighborhood Hits	572
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RIMB1_MOUSE
θ value	0.000121331 (rank : 403)	NC score	0.517707 (rank : 27)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1376	Shared Neighborhood Hits	772
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

STMN4_HUMAN
θ value	0.000121331 (rank : 404)	NC score	0.235539 (rank : 739)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	291
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
θ value	0.000121331 (rank : 405)	NC score	0.235457 (rank : 740)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	291
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

SYT7_MOUSE
θ value	0.000121331 (rank : 406)	NC score	0.177369 (rank : 937)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

TXK_MOUSE
θ value	0.000121331 (rank : 407)	NC score	0.124328 (rank : 1272)
Query Neighborhood Hits	1371	Target Neighborhood Hits	980	Shared Neighborhood Hits	214
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

CRK_HUMAN
θ value	0.000158464 (rank : 408)	NC score	0.351077 (rank : 467)
Query Neighborhood Hits	1371	Target Neighborhood Hits	308	Shared Neighborhood Hits	221
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	0.000158464 (rank : 409)	NC score	0.355410 (rank : 457)
Query Neighborhood Hits	1371	Target Neighborhood Hits	314	Shared Neighborhood Hits	221
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

HOOK1_MOUSE
θ value	0.000158464 (rank : 410)	NC score	0.470463 (rank : 166)
Query Neighborhood Hits	1371	Target Neighborhood Hits	910	Shared Neighborhood Hits	581
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_MOUSE
θ value	0.000158464 (rank : 411)	NC score	0.445554 (rank : 224)
Query Neighborhood Hits	1371	Target Neighborhood Hits	736	Shared Neighborhood Hits	532
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

KTN1_HUMAN
θ value	0.000158464 (rank : 412)	NC score	0.489892 (rank : 108)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1197	Shared Neighborhood Hits	661
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

PLEC1_HUMAN
θ value	0.000158464 (rank : 413)	NC score	0.417077 (rank : 307)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1326	Shared Neighborhood Hits	702
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RFIP1_MOUSE
θ value	0.000158464 (rank : 414)	NC score	0.126582 (rank : 1263)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SWP70_HUMAN
θ value	0.000158464 (rank : 415)	NC score	0.473962 (rank : 159)
Query Neighborhood Hits	1371	Target Neighborhood Hits	973	Shared Neighborhood Hits	625
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

UN13A_HUMAN
θ value	0.000158464 (rank : 416)	NC score	0.174237 (rank : 961)
Query Neighborhood Hits	1371	Target Neighborhood Hits	285	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

AN30A_HUMAN
θ value	0.00020696 (rank : 417)	NC score	0.354371 (rank : 460)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1119	Shared Neighborhood Hits	556
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CCD13_HUMAN
θ value	0.00020696 (rank : 418)	NC score	0.469526 (rank : 169)
Query Neighborhood Hits	1371	Target Neighborhood Hits	721	Shared Neighborhood Hits	492
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

IFT74_HUMAN
θ value	0.00020696 (rank : 419)	NC score	0.494989 (rank : 98)
Query Neighborhood Hits	1371	Target Neighborhood Hits	949	Shared Neighborhood Hits	591
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

KIF4A_MOUSE
θ value	0.00020696 (rank : 420)	NC score	0.363223 (rank : 438)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1033	Shared Neighborhood Hits	630
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NEMO_HUMAN
θ value	0.00020696 (rank : 421)	NC score	0.465970 (rank : 172)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	569
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

SWP70_MOUSE
θ value	0.00020696 (rank : 422)	NC score	0.472885 (rank : 162)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1097	Shared Neighborhood Hits	664
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TXLNA_HUMAN
θ value	0.00020696 (rank : 423)	NC score	0.395256 (rank : 370)
Query Neighborhood Hits	1371	Target Neighborhood Hits	982	Shared Neighborhood Hits	546
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNA_MOUSE
θ value	0.00020696 (rank : 424)	NC score	0.411297 (rank : 323)
Query Neighborhood Hits	1371	Target Neighborhood Hits	846	Shared Neighborhood Hits	552
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

BAIP2_HUMAN
θ value	0.000270298 (rank : 425)	NC score	0.202007 (rank : 838)
Query Neighborhood Hits	1371	Target Neighborhood Hits	192	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

CCD27_HUMAN
θ value	0.000270298 (rank : 426)	NC score	0.412635 (rank : 321)
Query Neighborhood Hits	1371	Target Neighborhood Hits	594	Shared Neighborhood Hits	420
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

DBNL_HUMAN
θ value	0.000270298 (rank : 427)	NC score	0.341948 (rank : 479)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	0.000270298 (rank : 428)	NC score	0.339517 (rank : 484)
Query Neighborhood Hits	1371	Target Neighborhood Hits	306	Shared Neighborhood Hits	227
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

MYH4_HUMAN
θ value	0.000270298 (rank : 429)	NC score	0.404922 (rank : 343)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1377	Shared Neighborhood Hits	731
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

NEB1_HUMAN
θ value	0.000270298 (rank : 430)	NC score	0.312978 (rank : 537)
Query Neighborhood Hits	1371	Target Neighborhood Hits	829	Shared Neighborhood Hits	450
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PACN1_MOUSE
θ value	0.000270298 (rank : 431)	NC score	0.347694 (rank : 473)
Query Neighborhood Hits	1371	Target Neighborhood Hits	283	Shared Neighborhood Hits	247
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PEPL_MOUSE
θ value	0.000270298 (rank : 432)	NC score	0.479414 (rank : 145)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1105	Shared Neighborhood Hits	679
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RABE1_MOUSE
θ value	0.000270298 (rank : 433)	NC score	0.478107 (rank : 150)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1105	Shared Neighborhood Hits	675
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RASL1_HUMAN
θ value	0.000270298 (rank : 434)	NC score	0.167681 (rank : 995)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	95
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

STAC_MOUSE
θ value	0.000270298 (rank : 435)	NC score	0.387294 (rank : 389)
Query Neighborhood Hits	1371	Target Neighborhood Hits	268	Shared Neighborhood Hits	203
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ZN291_HUMAN
θ value	0.000270298 (rank : 436)	NC score	0.435506 (rank : 249)
Query Neighborhood Hits	1371	Target Neighborhood Hits	647	Shared Neighborhood Hits	465
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

BCAR1_HUMAN
θ value	0.00035302 (rank : 437)	NC score	0.266563 (rank : 646)
Query Neighborhood Hits	1371	Target Neighborhood Hits	554	Shared Neighborhood Hits	199
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BICD2_MOUSE
θ value	0.00035302 (rank : 438)	NC score	0.447976 (rank : 216)
Query Neighborhood Hits	1371	Target Neighborhood Hits	864	Shared Neighborhood Hits	560
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CAR11_HUMAN
θ value	0.00035302 (rank : 439)	NC score	0.406328 (rank : 336)
Query Neighborhood Hits	1371	Target Neighborhood Hits	690	Shared Neighborhood Hits	505
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CARD9_HUMAN
θ value	0.00035302 (rank : 440)	NC score	0.432808 (rank : 260)
Query Neighborhood Hits	1371	Target Neighborhood Hits	602	Shared Neighborhood Hits	471
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CJ118_HUMAN
θ value	0.00035302 (rank : 441)	NC score	0.475861 (rank : 154)
Query Neighborhood Hits	1371	Target Neighborhood Hits	937	Shared Neighborhood Hits	597
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

DLG5_HUMAN
θ value	0.00035302 (rank : 442)	NC score	0.398164 (rank : 363)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1088	Shared Neighborhood Hits	596
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

EEA1_MOUSE
θ value	0.00035302 (rank : 443)	NC score	0.510817 (rank : 50)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1637	Shared Neighborhood Hits	782
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FLIP1_MOUSE
θ value	0.00035302 (rank : 444)	NC score	0.496508 (rank : 95)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1176	Shared Neighborhood Hits	682
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

HOOK2_HUMAN
θ value	0.00035302 (rank : 445)	NC score	0.428527 (rank : 274)
Query Neighborhood Hits	1371	Target Neighborhood Hits	714	Shared Neighborhood Hits	503
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

KIF5C_HUMAN
θ value	0.00035302 (rank : 446)	NC score	0.355420 (rank : 456)
Query Neighborhood Hits	1371	Target Neighborhood Hits	974	Shared Neighborhood Hits	618
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LRSM1_MOUSE
θ value	0.00035302 (rank : 447)	NC score	0.257323 (rank : 665)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	422
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MYO6_HUMAN
θ value	0.00035302 (rank : 448)	NC score	0.280754 (rank : 606)
Query Neighborhood Hits	1371	Target Neighborhood Hits	727	Shared Neighborhood Hits	518
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

RFIP1_HUMAN
θ value	0.00035302 (rank : 449)	NC score	0.115233 (rank : 1342)
Query Neighborhood Hits	1371	Target Neighborhood Hits	236	Shared Neighborhood Hits	65
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

STAC_HUMAN
θ value	0.00035302 (rank : 450)	NC score	0.393850 (rank : 376)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	209
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ANR21_HUMAN
θ value	0.000461057 (rank : 451)	NC score	0.157754 (rank : 1054)
Query Neighborhood Hits	1371	Target Neighborhood Hits	864	Shared Neighborhood Hits	379
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

CASL_HUMAN
θ value	0.000461057 (rank : 452)	NC score	0.256570 (rank : 670)
Query Neighborhood Hits	1371	Target Neighborhood Hits	259	Shared Neighborhood Hits	168
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CROCC_HUMAN
θ value	0.000461057 (rank : 453)	NC score	0.491047 (rank : 105)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1409	Shared Neighborhood Hits	734
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DOC2G_MOUSE
θ value	0.000461057 (rank : 454)	NC score	0.191076 (rank : 878)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

IFT81_HUMAN
θ value	0.000461057 (rank : 455)	NC score	0.488446 (rank : 113)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	599
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INCE_HUMAN
θ value	0.000461057 (rank : 456)	NC score	0.482024 (rank : 136)
Query Neighborhood Hits	1371	Target Neighborhood Hits	978	Shared Neighborhood Hits	586
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

K0528_HUMAN
θ value	0.000461057 (rank : 457)	NC score	0.176861 (rank : 940)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	0.000461057 (rank : 458)	NC score	0.176906 (rank : 939)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

RIMB2_HUMAN
θ value	0.000461057 (rank : 459)	NC score	0.244083 (rank : 718)
Query Neighborhood Hits	1371	Target Neighborhood Hits	263	Shared Neighborhood Hits	152
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RUFY1_MOUSE
θ value	0.000461057 (rank : 460)	NC score	0.417269 (rank : 306)
Query Neighborhood Hits	1371	Target Neighborhood Hits	765	Shared Neighborhood Hits	494
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

SYT7_HUMAN
θ value	0.000461057 (rank : 461)	NC score	0.179383 (rank : 928)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

CASL_MOUSE
θ value	0.000602161 (rank : 462)	NC score	0.253827 (rank : 683)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	166
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

DMD_MOUSE
θ value	0.000602161 (rank : 463)	NC score	0.377655 (rank : 409)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1111	Shared Neighborhood Hits	627
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DYHC_HUMAN
θ value	0.000602161 (rank : 464)	NC score	0.261902 (rank : 653)
Query Neighborhood Hits	1371	Target Neighborhood Hits	733	Shared Neighborhood Hits	481
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	0.000602161 (rank : 465)	NC score	0.261127 (rank : 656)
Query Neighborhood Hits	1371	Target Neighborhood Hits	729	Shared Neighborhood Hits	482
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

ES8L3_HUMAN
θ value	0.000602161 (rank : 466)	NC score	0.217412 (rank : 795)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

INVO_HUMAN
θ value	0.000602161 (rank : 467)	NC score	0.448121 (rank : 214)
Query Neighborhood Hits	1371	Target Neighborhood Hits	636	Shared Neighborhood Hits	405
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

K1H2_MOUSE
θ value	0.000602161 (rank : 468)	NC score	0.184312 (rank : 903)
Query Neighborhood Hits	1371	Target Neighborhood Hits	446	Shared Neighborhood Hits	335
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

PLCB4_HUMAN
θ value	0.000602161 (rank : 469)	NC score	0.326470 (rank : 508)
Query Neighborhood Hits	1371	Target Neighborhood Hits	658	Shared Neighborhood Hits	464
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

RFIP4_MOUSE
θ value	0.000602161 (rank : 470)	NC score	0.435076 (rank : 251)
Query Neighborhood Hits	1371	Target Neighborhood Hits	708	Shared Neighborhood Hits	526
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RIMB1_HUMAN
θ value	0.000602161 (rank : 471)	NC score	0.480201 (rank : 141)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1479	Shared Neighborhood Hits	735
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RUFY1_HUMAN
θ value	0.000602161 (rank : 472)	NC score	0.433681 (rank : 257)
Query Neighborhood Hits	1371	Target Neighborhood Hits	848	Shared Neighborhood Hits	552
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

TPM3_MOUSE
θ value	0.000602161 (rank : 473)	NC score	0.429511 (rank : 272)
Query Neighborhood Hits	1371	Target Neighborhood Hits	676	Shared Neighborhood Hits	483
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

VIME_HUMAN
θ value	0.000602161 (rank : 474)	NC score	0.259602 (rank : 658)
Query Neighborhood Hits	1371	Target Neighborhood Hits	706	Shared Neighborhood Hits	518
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

BAIP2_MOUSE
θ value	0.000786445 (rank : 475)	NC score	0.204534 (rank : 832)
Query Neighborhood Hits	1371	Target Neighborhood Hits	185	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

CAF1A_MOUSE
θ value	0.000786445 (rank : 476)	NC score	0.396506 (rank : 367)
Query Neighborhood Hits	1371	Target Neighborhood Hits	736	Shared Neighborhood Hits	499
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CF182_HUMAN
θ value	0.000786445 (rank : 477)	NC score	0.359651 (rank : 447)
Query Neighborhood Hits	1371	Target Neighborhood Hits	474	Shared Neighborhood Hits	369
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CK5P2_MOUSE
θ value	0.000786445 (rank : 478)	NC score	0.479358 (rank : 147)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1151	Shared Neighborhood Hits	663
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CR034_MOUSE
θ value	0.000786445 (rank : 479)	NC score	0.419906 (rank : 301)
Query Neighborhood Hits	1371	Target Neighborhood Hits	643	Shared Neighborhood Hits	466
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CROCC_MOUSE
θ value	0.000786445 (rank : 480)	NC score	0.489987 (rank : 107)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1460	Shared Neighborhood Hits	752
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

EM55_HUMAN
θ value	0.000786445 (rank : 481)	NC score	0.143945 (rank : 1136)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	114
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

INCE_MOUSE
θ value	0.000786445 (rank : 482)	NC score	0.481454 (rank : 139)
Query Neighborhood Hits	1371	Target Neighborhood Hits	903	Shared Neighborhood Hits	598
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

KIF5C_MOUSE
θ value	0.000786445 (rank : 483)	NC score	0.370882 (rank : 418)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1040	Shared Neighborhood Hits	662
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KPCG_HUMAN
θ value	0.000786445 (rank : 484)	NC score	0.102179 (rank : 1443)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1126	Shared Neighborhood Hits	193
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

LRRF2_HUMAN
θ value	0.000786445 (rank : 485)	NC score	0.455009 (rank : 193)
Query Neighborhood Hits	1371	Target Neighborhood Hits	791	Shared Neighborhood Hits	540
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

M4K4_HUMAN
θ value	0.000786445 (rank : 486)	NC score	0.170572 (rank : 980)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1589	Shared Neighborhood Hits	601
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	0.000786445 (rank : 487)	NC score	0.166408 (rank : 1001)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1560	Shared Neighborhood Hits	578
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MYH13_HUMAN
θ value	0.000786445 (rank : 488)	NC score	0.418335 (rank : 304)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1504	Shared Neighborhood Hits	758
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYO5B_HUMAN
θ value	0.000786445 (rank : 489)	NC score	0.317552 (rank : 529)
Query Neighborhood Hits	1371	Target Neighborhood Hits	911	Shared Neighborhood Hits	582
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

SPTA1_HUMAN
θ value	0.000786445 (rank : 490)	NC score	0.394844 (rank : 372)
Query Neighborhood Hits	1371	Target Neighborhood Hits	748	Shared Neighborhood Hits	564
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TPM4_HUMAN
θ value	0.000786445 (rank : 491)	NC score	0.400109 (rank : 358)
Query Neighborhood Hits	1371	Target Neighborhood Hits	525	Shared Neighborhood Hits	405
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

VIME_MOUSE
θ value	0.000786445 (rank : 492)	NC score	0.263846 (rank : 649)
Query Neighborhood Hits	1371	Target Neighborhood Hits	716	Shared Neighborhood Hits	513
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

ASPP1_MOUSE
θ value	0.00102713 (rank : 493)	NC score	0.332510 (rank : 499)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1244	Shared Neighborhood Hits	521
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BLK_MOUSE
θ value	0.00102713 (rank : 494)	NC score	0.127179 (rank : 1259)
Query Neighborhood Hits	1371	Target Neighborhood Hits	992	Shared Neighborhood Hits	202
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

ES8L3_MOUSE
θ value	0.00102713 (rank : 495)	NC score	0.226470 (rank : 765)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	149
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

KI21A_MOUSE
θ value	0.00102713 (rank : 496)	NC score	0.298165 (rank : 569)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1317	Shared Neighborhood Hits	647
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LUZP1_MOUSE
θ value	0.00102713 (rank : 497)	NC score	0.450328 (rank : 206)
Query Neighborhood Hits	1371	Target Neighborhood Hits	940	Shared Neighborhood Hits	570
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MACF1_MOUSE
θ value	0.00102713 (rank : 498)	NC score	0.351821 (rank : 464)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1313	Shared Neighborhood Hits	658
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

RAI14_HUMAN
θ value	0.00102713 (rank : 499)	NC score	0.350805 (rank : 468)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1367	Shared Neighborhood Hits	657
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

SPTA1_MOUSE
θ value	0.00102713 (rank : 500)	NC score	0.368567 (rank : 426)
Query Neighborhood Hits	1371	Target Neighborhood Hits	675	Shared Neighborhood Hits	516
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

UACA_HUMAN
θ value	0.00102713 (rank : 501)	NC score	0.415929 (rank : 311)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1622	Shared Neighborhood Hits	734
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

GFAP_MOUSE
θ value	0.00134147 (rank : 502)	NC score	0.256424 (rank : 671)
Query Neighborhood Hits	1371	Target Neighborhood Hits	725	Shared Neighborhood Hits	523
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

KIF5A_MOUSE
θ value	0.00134147 (rank : 503)	NC score	0.333020 (rank : 497)
Query Neighborhood Hits	1371	Target Neighborhood Hits	859	Shared Neighborhood Hits	564
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LZTS2_HUMAN
θ value	0.00134147 (rank : 504)	NC score	0.356389 (rank : 453)
Query Neighborhood Hits	1371	Target Neighborhood Hits	427	Shared Neighborhood Hits	321
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

NAF1_MOUSE
θ value	0.00134147 (rank : 505)	NC score	0.444831 (rank : 227)
Query Neighborhood Hits	1371	Target Neighborhood Hits	852	Shared Neighborhood Hits	572
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

SLK_HUMAN
θ value	0.00134147 (rank : 506)	NC score	0.186843 (rank : 891)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1775	Shared Neighborhood Hits	656
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
θ value	0.00134147 (rank : 507)	NC score	0.182979 (rank : 907)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1798	Shared Neighborhood Hits	650
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TAOK2_MOUSE
θ value	0.00134147 (rank : 508)	NC score	0.154529 (rank : 1075)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1373	Shared Neighborhood Hits	478
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

TPM3_HUMAN
θ value	0.00134147 (rank : 509)	NC score	0.430779 (rank : 266)
Query Neighborhood Hits	1371	Target Neighborhood Hits	689	Shared Neighborhood Hits	486
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

ANGL3_MOUSE
θ value	0.00175202 (rank : 510)	NC score	0.108580 (rank : 1387)
Query Neighborhood Hits	1371	Target Neighborhood Hits	306	Shared Neighborhood Hits	221
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

BLK_HUMAN
θ value	0.00175202 (rank : 511)	NC score	0.128983 (rank : 1241)
Query Neighborhood Hits	1371	Target Neighborhood Hits	994	Shared Neighborhood Hits	211
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

CCD19_HUMAN
θ value	0.00175202 (rank : 512)	NC score	0.482780 (rank : 131)
Query Neighborhood Hits	1371	Target Neighborhood Hits	639	Shared Neighborhood Hits	516
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CNTRB_MOUSE
θ value	0.00175202 (rank : 513)	NC score	0.450099 (rank : 209)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1029	Shared Neighborhood Hits	588
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

GOGA2_HUMAN
θ value	0.00175202 (rank : 514)	NC score	0.464409 (rank : 176)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	553
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

K1H7_HUMAN
θ value	0.00175202 (rank : 515)	NC score	0.151517 (rank : 1089)
Query Neighborhood Hits	1371	Target Neighborhood Hits	369	Shared Neighborhood Hits	290
SwissProt Accessions	O76014	Gene names	KRTHA7, HHA7, HKA7
Domain Architecture
Description	Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7).

KIF5A_HUMAN
θ value	0.00175202 (rank : 516)	NC score	0.335930 (rank : 491)
Query Neighborhood Hits	1371	Target Neighborhood Hits	843	Shared Neighborhood Hits	560
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIFC1_HUMAN
θ value	0.00175202 (rank : 517)	NC score	0.257352 (rank : 664)
Query Neighborhood Hits	1371	Target Neighborhood Hits	545	Shared Neighborhood Hits	407
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

LCK_HUMAN
θ value	0.00175202 (rank : 518)	NC score	0.117770 (rank : 1317)
Query Neighborhood Hits	1371	Target Neighborhood Hits	987	Shared Neighborhood Hits	193
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	0.00175202 (rank : 519)	NC score	0.117320 (rank : 1319)
Query Neighborhood Hits	1371	Target Neighborhood Hits	981	Shared Neighborhood Hits	191
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

MYO6_MOUSE
θ value	0.00175202 (rank : 520)	NC score	0.257011 (rank : 668)
Query Neighborhood Hits	1371	Target Neighborhood Hits	586	Shared Neighborhood Hits	443
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

PHLB2_HUMAN
θ value	0.00175202 (rank : 521)	NC score	0.402309 (rank : 350)
Query Neighborhood Hits	1371	Target Neighborhood Hits	964	Shared Neighborhood Hits	578
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PLCB2_HUMAN
θ value	0.00175202 (rank : 522)	NC score	0.264375 (rank : 647)
Query Neighborhood Hits	1371	Target Neighborhood Hits	608	Shared Neighborhood Hits	422
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

SHAN1_HUMAN
θ value	0.00175202 (rank : 523)	NC score	0.166090 (rank : 1002)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1041	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SYNG_HUMAN
θ value	0.00175202 (rank : 524)	NC score	0.114094 (rank : 1354)
Query Neighborhood Hits	1371	Target Neighborhood Hits	160	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SYNG_MOUSE
θ value	0.00175202 (rank : 525)	NC score	0.122940 (rank : 1281)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	57
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SYT10_MOUSE
θ value	0.00175202 (rank : 526)	NC score	0.168439 (rank : 993)
Query Neighborhood Hits	1371	Target Neighborhood Hits	133	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

TCGAP_HUMAN
θ value	0.00175202 (rank : 527)	NC score	0.165527 (rank : 1005)
Query Neighborhood Hits	1371	Target Neighborhood Hits	872	Shared Neighborhood Hits	187
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	0.00175202 (rank : 528)	NC score	0.184253 (rank : 904)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	156
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CCD45_MOUSE
θ value	0.00228821 (rank : 529)	NC score	0.337858 (rank : 487)
Query Neighborhood Hits	1371	Target Neighborhood Hits	663	Shared Neighborhood Hits	395
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCDC6_HUMAN
θ value	0.00228821 (rank : 530)	NC score	0.474722 (rank : 158)
Query Neighborhood Hits	1371	Target Neighborhood Hits	723	Shared Neighborhood Hits	511
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CN140_MOUSE
θ value	0.00228821 (rank : 531)	NC score	0.130516 (rank : 1235)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	117
SwissProt Accessions	Q8CCG1, Q8CCM8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf140 homolog.

GRAP1_HUMAN
θ value	0.00228821 (rank : 532)	NC score	0.490172 (rank : 106)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	618
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

KPCG_MOUSE
θ value	0.00228821 (rank : 533)	NC score	0.101338 (rank : 1451)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1123	Shared Neighborhood Hits	192
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

LIPA2_HUMAN
θ value	0.00228821 (rank : 534)	NC score	0.437501 (rank : 243)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1044	Shared Neighborhood Hits	658
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LZTS2_MOUSE
θ value	0.00228821 (rank : 535)	NC score	0.332013 (rank : 501)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	295
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

MYH14_MOUSE
θ value	0.00228821 (rank : 536)	NC score	0.396915 (rank : 366)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1225	Shared Neighborhood Hits	699
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

RADI_HUMAN
θ value	0.00228821 (rank : 537)	NC score	0.301077 (rank : 562)
Query Neighborhood Hits	1371	Target Neighborhood Hits	741	Shared Neighborhood Hits	519
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RIMB2_MOUSE
θ value	0.00228821 (rank : 538)	NC score	0.253919 (rank : 681)
Query Neighborhood Hits	1371	Target Neighborhood Hits	246	Shared Neighborhood Hits	158
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RUSC1_HUMAN
θ value	0.00228821 (rank : 539)	NC score	0.234015 (rank : 743)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

TPM1_HUMAN
θ value	0.00228821 (rank : 540)	NC score	0.423777 (rank : 286)
Query Neighborhood Hits	1371	Target Neighborhood Hits	716	Shared Neighborhood Hits	512
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	0.00228821 (rank : 541)	NC score	0.427714 (rank : 275)
Query Neighborhood Hits	1371	Target Neighborhood Hits	729	Shared Neighborhood Hits	523
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM4_MOUSE
θ value	0.00228821 (rank : 542)	NC score	0.425821 (rank : 278)
Query Neighborhood Hits	1371	Target Neighborhood Hits	703	Shared Neighborhood Hits	514
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

ASPP2_HUMAN
θ value	0.00298849 (rank : 543)	NC score	0.359692 (rank : 446)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1156	Shared Neighborhood Hits	569
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

AZI1_MOUSE
θ value	0.00298849 (rank : 544)	NC score	0.488601 (rank : 112)
Query Neighborhood Hits	1371	Target Neighborhood Hits	990	Shared Neighborhood Hits	645
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CALM4_MOUSE
θ value	0.00298849 (rank : 545)	NC score	0.068429 (rank : 1773)
Query Neighborhood Hits	1371	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CALM_HUMAN
θ value	0.00298849 (rank : 546)	NC score	0.046647 (rank : 2193)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	0.00298849 (rank : 547)	NC score	0.046647 (rank : 2194)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CEP55_MOUSE
θ value	0.00298849 (rank : 548)	NC score	0.456363 (rank : 190)
Query Neighborhood Hits	1371	Target Neighborhood Hits	693	Shared Neighborhood Hits	511
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CING_HUMAN
θ value	0.00298849 (rank : 549)	NC score	0.493766 (rank : 101)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1275	Shared Neighborhood Hits	720
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

GFAP_HUMAN
θ value	0.00298849 (rank : 550)	NC score	0.261330 (rank : 654)
Query Neighborhood Hits	1371	Target Neighborhood Hits	723	Shared Neighborhood Hits	522
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

LAMA2_MOUSE
θ value	0.00298849 (rank : 551)	NC score	0.221159 (rank : 783)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1198	Shared Neighborhood Hits	454
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MOES_MOUSE
θ value	0.00298849 (rank : 552)	NC score	0.346814 (rank : 475)
Query Neighborhood Hits	1371	Target Neighborhood Hits	923	Shared Neighborhood Hits	600
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MPP5_HUMAN
θ value	0.00298849 (rank : 553)	NC score	0.115045 (rank : 1343)
Query Neighborhood Hits	1371	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.00298849 (rank : 554)	NC score	0.114015 (rank : 1355)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MY18B_HUMAN
θ value	0.00298849 (rank : 555)	NC score	0.401808 (rank : 351)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1299	Shared Neighborhood Hits	610
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

PCNT_MOUSE
θ value	0.00298849 (rank : 556)	NC score	0.483637 (rank : 129)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1207	Shared Neighborhood Hits	688
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PEX13_MOUSE
θ value	0.00298849 (rank : 557)	NC score	0.252441 (rank : 688)
Query Neighborhood Hits	1371	Target Neighborhood Hits	126	Shared Neighborhood Hits	118
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PTK6_MOUSE
θ value	0.00298849 (rank : 558)	NC score	0.120290 (rank : 1300)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1026	Shared Neighborhood Hits	233
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

RFIP2_HUMAN
θ value	0.00298849 (rank : 559)	NC score	0.170735 (rank : 979)
Query Neighborhood Hits	1371	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

SYT9_HUMAN
θ value	0.00298849 (rank : 560)	NC score	0.164317 (rank : 1017)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	89
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

TUFT1_MOUSE
θ value	0.00298849 (rank : 561)	NC score	0.451456 (rank : 204)
Query Neighborhood Hits	1371	Target Neighborhood Hits	732	Shared Neighborhood Hits	509
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

UN13B_MOUSE
θ value	0.00298849 (rank : 562)	NC score	0.165551 (rank : 1004)
Query Neighborhood Hits	1371	Target Neighborhood Hits	210	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ASPP1_HUMAN
θ value	0.00390308 (rank : 563)	NC score	0.334298 (rank : 494)
Query Neighborhood Hits	1371	Target Neighborhood Hits	956	Shared Neighborhood Hits	485
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CT032_HUMAN
θ value	0.00390308 (rank : 564)	NC score	0.286328 (rank : 590)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CTRO_HUMAN
θ value	0.00390308 (rank : 565)	NC score	0.286021 (rank : 591)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2092	Shared Neighborhood Hits	781
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ES8L1_MOUSE
θ value	0.00390308 (rank : 566)	NC score	0.169675 (rank : 984)
Query Neighborhood Hits	1371	Target Neighborhood Hits	143	Shared Neighborhood Hits	98
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

IQGA1_HUMAN
θ value	0.00390308 (rank : 567)	NC score	0.112363 (rank : 1368)
Query Neighborhood Hits	1371	Target Neighborhood Hits	250	Shared Neighborhood Hits	152
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

LUZP1_HUMAN
θ value	0.00390308 (rank : 568)	NC score	0.432948 (rank : 258)
Query Neighborhood Hits	1371	Target Neighborhood Hits	739	Shared Neighborhood Hits	486
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MYH14_HUMAN
θ value	0.00390308 (rank : 569)	NC score	0.372332 (rank : 415)
Query Neighborhood Hits	1371	Target Neighborhood Hits	995	Shared Neighborhood Hits	600
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NFM_MOUSE
θ value	0.00390308 (rank : 570)	NC score	0.304343 (rank : 552)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1159	Shared Neighborhood Hits	634
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

SYT6_HUMAN
θ value	0.00390308 (rank : 571)	NC score	0.165239 (rank : 1009)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	83
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYTL5_HUMAN
θ value	0.00390308 (rank : 572)	NC score	0.147664 (rank : 1111)
Query Neighborhood Hits	1371	Target Neighborhood Hits	237	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

TMF1_HUMAN
θ value	0.00390308 (rank : 573)	NC score	0.481824 (rank : 138)
Query Neighborhood Hits	1371	Target Neighborhood Hits	987	Shared Neighborhood Hits	600
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TOLIP_MOUSE
θ value	0.00390308 (rank : 574)	NC score	0.086308 (rank : 1572)
Query Neighborhood Hits	1371	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

TRAIP_HUMAN
θ value	0.00390308 (rank : 575)	NC score	0.401623 (rank : 352)
Query Neighborhood Hits	1371	Target Neighborhood Hits	780	Shared Neighborhood Hits	461
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TSC1_HUMAN
θ value	0.00390308 (rank : 576)	NC score	0.434140 (rank : 255)
Query Neighborhood Hits	1371	Target Neighborhood Hits	765	Shared Neighborhood Hits	466
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

CANB1_HUMAN
θ value	0.00509761 (rank : 577)	NC score	0.045016 (rank : 2203)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	37
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
θ value	0.00509761 (rank : 578)	NC score	0.044994 (rank : 2204)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	37
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CCD93_HUMAN
θ value	0.00509761 (rank : 579)	NC score	0.387425 (rank : 388)
Query Neighborhood Hits	1371	Target Neighborhood Hits	600	Shared Neighborhood Hits	436
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CSKP_HUMAN
θ value	0.00509761 (rank : 580)	NC score	0.083182 (rank : 1607)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1022	Shared Neighborhood Hits	198
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CTTB2_HUMAN
θ value	0.00509761 (rank : 581)	NC score	0.244307 (rank : 716)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1061	Shared Neighborhood Hits	525
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

GCC1_HUMAN
θ value	0.00509761 (rank : 582)	NC score	0.460056 (rank : 183)
Query Neighborhood Hits	1371	Target Neighborhood Hits	887	Shared Neighborhood Hits	571
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

HOME1_MOUSE
θ value	0.00509761 (rank : 583)	NC score	0.337382 (rank : 488)
Query Neighborhood Hits	1371	Target Neighborhood Hits	630	Shared Neighborhood Hits	435
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

NPHP1_MOUSE
θ value	0.00509761 (rank : 584)	NC score	0.365274 (rank : 432)
Query Neighborhood Hits	1371	Target Neighborhood Hits	267	Shared Neighborhood Hits	237
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

RADI_MOUSE
θ value	0.00509761 (rank : 585)	NC score	0.302481 (rank : 556)
Query Neighborhood Hits	1371	Target Neighborhood Hits	773	Shared Neighborhood Hits	530
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

SPTB2_MOUSE
θ value	0.00509761 (rank : 586)	NC score	0.298801 (rank : 566)
Query Neighborhood Hits	1371	Target Neighborhood Hits	770	Shared Neighborhood Hits	477
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SYT9_MOUSE
θ value	0.00509761 (rank : 587)	NC score	0.163513 (rank : 1019)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

UN84B_MOUSE
θ value	0.00509761 (rank : 588)	NC score	0.138046 (rank : 1175)
Query Neighborhood Hits	1371	Target Neighborhood Hits	194	Shared Neighborhood Hits	156
SwissProt Accessions	Q8BJS4	Gene names	Unc84b, Sun2
Domain Architecture	No domain graphic available
Description	Sad1/unc-84-like protein 2.

BFSP2_MOUSE
θ value	0.00665767 (rank : 589)	NC score	0.195112 (rank : 860)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	303
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

CCD45_HUMAN
θ value	0.00665767 (rank : 590)	NC score	0.340914 (rank : 481)
Query Neighborhood Hits	1371	Target Neighborhood Hits	525	Shared Neighborhood Hits	364
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD91_MOUSE
θ value	0.00665767 (rank : 591)	NC score	0.439547 (rank : 239)
Query Neighborhood Hits	1371	Target Neighborhood Hits	699	Shared Neighborhood Hits	490
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCHCR_MOUSE
θ value	0.00665767 (rank : 592)	NC score	0.476052 (rank : 152)
Query Neighborhood Hits	1371	Target Neighborhood Hits	932	Shared Neighborhood Hits	604
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CDC37_HUMAN
θ value	0.00665767 (rank : 593)	NC score	0.307796 (rank : 545)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	357
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

GAS8_MOUSE
θ value	0.00665767 (rank : 594)	NC score	0.457530 (rank : 185)
Query Neighborhood Hits	1371	Target Neighborhood Hits	622	Shared Neighborhood Hits	484
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

KIF23_HUMAN
θ value	0.00665767 (rank : 595)	NC score	0.273634 (rank : 628)
Query Neighborhood Hits	1371	Target Neighborhood Hits	618	Shared Neighborhood Hits	451
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

MFAP1_MOUSE
θ value	0.00665767 (rank : 596)	NC score	0.333105 (rank : 496)
Query Neighborhood Hits	1371	Target Neighborhood Hits	353	Shared Neighborhood Hits	271
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

NAF1_HUMAN
θ value	0.00665767 (rank : 597)	NC score	0.442190 (rank : 232)
Query Neighborhood Hits	1371	Target Neighborhood Hits	937	Shared Neighborhood Hits	585
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NEMO_MOUSE
θ value	0.00665767 (rank : 598)	NC score	0.440448 (rank : 237)
Query Neighborhood Hits	1371	Target Neighborhood Hits	658	Shared Neighborhood Hits	489
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

RUFY3_MOUSE
θ value	0.00665767 (rank : 599)	NC score	0.377522 (rank : 410)
Query Neighborhood Hits	1371	Target Neighborhood Hits	579	Shared Neighborhood Hits	456
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUSC1_MOUSE
θ value	0.00665767 (rank : 600)	NC score	0.217197 (rank : 797)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	142
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

RUSC2_HUMAN
θ value	0.00665767 (rank : 601)	NC score	0.122721 (rank : 1282)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SYTL4_HUMAN
θ value	0.00665767 (rank : 602)	NC score	0.150225 (rank : 1093)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	81
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

CALD1_HUMAN
θ value	0.00869519 (rank : 603)	NC score	0.473730 (rank : 160)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	583
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CF182_MOUSE
θ value	0.00869519 (rank : 604)	NC score	0.385986 (rank : 393)
Query Neighborhood Hits	1371	Target Neighborhood Hits	551	Shared Neighborhood Hits	396
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

EM55_MOUSE
θ value	0.00869519 (rank : 605)	NC score	0.138274 (rank : 1174)
Query Neighborhood Hits	1371	Target Neighborhood Hits	221	Shared Neighborhood Hits	112
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

GOGA2_MOUSE
θ value	0.00869519 (rank : 606)	NC score	0.486716 (rank : 119)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	601
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

HOME1_HUMAN
θ value	0.00869519 (rank : 607)	NC score	0.324256 (rank : 511)
Query Neighborhood Hits	1371	Target Neighborhood Hits	564	Shared Neighborhood Hits	411
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

K2C1B_MOUSE
θ value	0.00869519 (rank : 608)	NC score	0.181434 (rank : 917)
Query Neighborhood Hits	1371	Target Neighborhood Hits	503	Shared Neighborhood Hits	369
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

KIF3B_HUMAN
θ value	0.00869519 (rank : 609)	NC score	0.225599 (rank : 768)
Query Neighborhood Hits	1371	Target Neighborhood Hits	540	Shared Neighborhood Hits	408
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

LIPB1_MOUSE
θ value	0.00869519 (rank : 610)	NC score	0.368660 (rank : 425)
Query Neighborhood Hits	1371	Target Neighborhood Hits	727	Shared Neighborhood Hits	496
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MFAP1_HUMAN
θ value	0.00869519 (rank : 611)	NC score	0.290777 (rank : 583)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	242
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MINT_MOUSE
θ value	0.00869519 (rank : 612)	NC score	0.103665 (rank : 1434)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1514	Shared Neighborhood Hits	298
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

OFD1_HUMAN
θ value	0.00869519 (rank : 613)	NC score	0.456670 (rank : 188)
Query Neighborhood Hits	1371	Target Neighborhood Hits	753	Shared Neighborhood Hits	520
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

P55G_HUMAN
θ value	0.00869519 (rank : 614)	NC score	0.245050 (rank : 712)
Query Neighborhood Hits	1371	Target Neighborhood Hits	451	Shared Neighborhood Hits	321
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

STMN1_HUMAN
θ value	0.00869519 (rank : 615)	NC score	0.272078 (rank : 632)
Query Neighborhood Hits	1371	Target Neighborhood Hits	554	Shared Neighborhood Hits	358
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

STMN1_MOUSE
θ value	0.00869519 (rank : 616)	NC score	0.266980 (rank : 644)
Query Neighborhood Hits	1371	Target Neighborhood Hits	560	Shared Neighborhood Hits	358
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

TPM2_HUMAN
θ value	0.00869519 (rank : 617)	NC score	0.421501 (rank : 296)
Query Neighborhood Hits	1371	Target Neighborhood Hits	677	Shared Neighborhood Hits	477
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

ZWINT_MOUSE
θ value	0.00869519 (rank : 618)	NC score	0.369097 (rank : 422)
Query Neighborhood Hits	1371	Target Neighborhood Hits	497	Shared Neighborhood Hits	384
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

BRE1A_HUMAN
θ value	0.0113563 (rank : 619)	NC score	0.450237 (rank : 207)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1071	Shared Neighborhood Hits	622
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CTGE5_HUMAN
θ value	0.0113563 (rank : 620)	NC score	0.396027 (rank : 369)
Query Neighborhood Hits	1371	Target Neighborhood Hits	800	Shared Neighborhood Hits	537
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DMN_HUMAN
θ value	0.0113563 (rank : 621)	NC score	0.172927 (rank : 967)
Query Neighborhood Hits	1371	Target Neighborhood Hits	690	Shared Neighborhood Hits	354
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

FRK_HUMAN
θ value	0.0113563 (rank : 622)	NC score	0.130091 (rank : 1237)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1058	Shared Neighborhood Hits	260
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

KIF3B_MOUSE
θ value	0.0113563 (rank : 623)	NC score	0.220450 (rank : 787)
Query Neighborhood Hits	1371	Target Neighborhood Hits	533	Shared Neighborhood Hits	399
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

LRSM1_HUMAN
θ value	0.0113563 (rank : 624)	NC score	0.303254 (rank : 554)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1078	Shared Neighborhood Hits	521
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MACF1_HUMAN
θ value	0.0113563 (rank : 625)	NC score	0.359379 (rank : 448)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1341	Shared Neighborhood Hits	664
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.0113563 (rank : 626)	NC score	0.391354 (rank : 381)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1321	Shared Neighborhood Hits	653
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MDC1_HUMAN
θ value	0.0113563 (rank : 627)	NC score	0.089042 (rank : 1550)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1446	Shared Neighborhood Hits	280
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MPP3_MOUSE
θ value	0.0113563 (rank : 628)	NC score	0.092084 (rank : 1527)
Query Neighborhood Hits	1371	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

NOP14_HUMAN
θ value	0.0113563 (rank : 629)	NC score	0.240735 (rank : 725)
Query Neighborhood Hits	1371	Target Neighborhood Hits	573	Shared Neighborhood Hits	328
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

P55G_MOUSE
θ value	0.0113563 (rank : 630)	NC score	0.225400 (rank : 769)
Query Neighborhood Hits	1371	Target Neighborhood Hits	401	Shared Neighborhood Hits	275
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PA24F_MOUSE
θ value	0.0113563 (rank : 631)	NC score	0.097555 (rank : 1479)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	68
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

RBBP8_HUMAN
θ value	0.0113563 (rank : 632)	NC score	0.293973 (rank : 578)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	323
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

SYT6_MOUSE
θ value	0.0113563 (rank : 633)	NC score	0.164558 (rank : 1015)
Query Neighborhood Hits	1371	Target Neighborhood Hits	132	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

TEX9_MOUSE
θ value	0.0113563 (rank : 634)	NC score	0.413814 (rank : 320)
Query Neighborhood Hits	1371	Target Neighborhood Hits	581	Shared Neighborhood Hits	455
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TPM2_MOUSE
θ value	0.0113563 (rank : 635)	NC score	0.419036 (rank : 302)
Query Neighborhood Hits	1371	Target Neighborhood Hits	676	Shared Neighborhood Hits	476
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TUFT1_HUMAN
θ value	0.0113563 (rank : 636)	NC score	0.452350 (rank : 200)
Query Neighborhood Hits	1371	Target Neighborhood Hits	686	Shared Neighborhood Hits	494
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TXK_HUMAN
θ value	0.0113563 (rank : 637)	NC score	0.118398 (rank : 1313)
Query Neighborhood Hits	1371	Target Neighborhood Hits	971	Shared Neighborhood Hits	201
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

ABL1_HUMAN
θ value	0.0148317 (rank : 638)	NC score	0.114567 (rank : 1349)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1220	Shared Neighborhood Hits	224
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	0.0148317 (rank : 639)	NC score	0.114168 (rank : 1352)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1178	Shared Neighborhood Hits	220
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ANGL3_HUMAN
θ value	0.0148317 (rank : 640)	NC score	0.097837 (rank : 1477)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

CSK_HUMAN
θ value	0.0148317 (rank : 641)	NC score	0.115585 (rank : 1336)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	209
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	0.0148317 (rank : 642)	NC score	0.116272 (rank : 1331)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	209
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

GCC1_MOUSE
θ value	0.0148317 (rank : 643)	NC score	0.451630 (rank : 203)
Query Neighborhood Hits	1371	Target Neighborhood Hits	777	Shared Neighborhood Hits	518
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

HIP1R_MOUSE
θ value	0.0148317 (rank : 644)	NC score	0.431769 (rank : 264)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	591
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

MACOI_HUMAN
θ value	0.0148317 (rank : 645)	NC score	0.406546 (rank : 335)
Query Neighborhood Hits	1371	Target Neighborhood Hits	650	Shared Neighborhood Hits	456
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MOES_HUMAN
θ value	0.0148317 (rank : 646)	NC score	0.340450 (rank : 483)
Query Neighborhood Hits	1371	Target Neighborhood Hits	892	Shared Neighborhood Hits	595
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NFM_HUMAN
θ value	0.0148317 (rank : 647)	NC score	0.299227 (rank : 565)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1328	Shared Neighborhood Hits	638
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NUP88_HUMAN
θ value	0.0148317 (rank : 648)	NC score	0.253551 (rank : 685)
Query Neighborhood Hits	1371	Target Neighborhood Hits	354	Shared Neighborhood Hits	290
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

PA24E_HUMAN
θ value	0.0148317 (rank : 649)	NC score	0.115731 (rank : 1333)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

RASL1_MOUSE
θ value	0.0148317 (rank : 650)	NC score	0.157459 (rank : 1059)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RUFY3_HUMAN
θ value	0.0148317 (rank : 651)	NC score	0.381901 (rank : 400)
Query Neighborhood Hits	1371	Target Neighborhood Hits	594	Shared Neighborhood Hits	463
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

STS2_HUMAN
θ value	0.0148317 (rank : 652)	NC score	0.168949 (rank : 989)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	87
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SYNE2_HUMAN
θ value	0.0148317 (rank : 653)	NC score	0.381511 (rank : 402)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1323	Shared Neighborhood Hits	666
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

UN13B_HUMAN
θ value	0.0148317 (rank : 654)	NC score	0.158999 (rank : 1043)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	120
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

BAIP3_HUMAN
θ value	0.0193708 (rank : 655)	NC score	0.143613 (rank : 1140)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	78
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CANB2_HUMAN
θ value	0.0193708 (rank : 656)	NC score	0.045988 (rank : 2196)
Query Neighborhood Hits	1371	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

CCD27_MOUSE
θ value	0.0193708 (rank : 657)	NC score	0.399462 (rank : 359)
Query Neighborhood Hits	1371	Target Neighborhood Hits	461	Shared Neighborhood Hits	357
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD42_HUMAN
θ value	0.0193708 (rank : 658)	NC score	0.349514 (rank : 471)
Query Neighborhood Hits	1371	Target Neighborhood Hits	406	Shared Neighborhood Hits	346
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CT2NL_MOUSE
θ value	0.0193708 (rank : 659)	NC score	0.422924 (rank : 291)
Query Neighborhood Hits	1371	Target Neighborhood Hits	902	Shared Neighborhood Hits	562
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

EFS_MOUSE
θ value	0.0193708 (rank : 660)	NC score	0.267324 (rank : 642)
Query Neighborhood Hits	1371	Target Neighborhood Hits	389	Shared Neighborhood Hits	186
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ENAH_HUMAN
θ value	0.0193708 (rank : 661)	NC score	0.337127 (rank : 489)
Query Neighborhood Hits	1371	Target Neighborhood Hits	784	Shared Neighborhood Hits	456
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EXOC1_MOUSE
θ value	0.0193708 (rank : 662)	NC score	0.146017 (rank : 1125)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	149
SwissProt Accessions	Q8R3S6	Gene names	Exoc1, Sec3, Sec3l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

IFT74_MOUSE
θ value	0.0193708 (rank : 663)	NC score	0.485171 (rank : 123)
Query Neighborhood Hits	1371	Target Neighborhood Hits	939	Shared Neighborhood Hits	594
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

ITK_HUMAN
θ value	0.0193708 (rank : 664)	NC score	0.114628 (rank : 1347)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1016	Shared Neighborhood Hits	215
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

JIP3_HUMAN
θ value	0.0193708 (rank : 665)	NC score	0.273736 (rank : 627)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1039	Shared Neighborhood Hits	507
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

K2C1_HUMAN
θ value	0.0193708 (rank : 666)	NC score	0.230277 (rank : 752)
Query Neighborhood Hits	1371	Target Neighborhood Hits	624	Shared Neighborhood Hits	423
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

LIPB1_HUMAN
θ value	0.0193708 (rank : 667)	NC score	0.358878 (rank : 450)
Query Neighborhood Hits	1371	Target Neighborhood Hits	640	Shared Neighborhood Hits	450
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

MPP3_HUMAN
θ value	0.0193708 (rank : 668)	NC score	0.091867 (rank : 1528)
Query Neighborhood Hits	1371	Target Neighborhood Hits	171	Shared Neighborhood Hits	61
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

RPTN_MOUSE
θ value	0.0193708 (rank : 669)	NC score	0.048833 (rank : 2183)
Query Neighborhood Hits	1371	Target Neighborhood Hits	650	Shared Neighborhood Hits	134
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RUFY2_MOUSE
θ value	0.0193708 (rank : 670)	NC score	0.420697 (rank : 297)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	544
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

TOLIP_HUMAN
θ value	0.0193708 (rank : 671)	NC score	0.076151 (rank : 1678)
Query Neighborhood Hits	1371	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

UTRO_HUMAN
θ value	0.0193708 (rank : 672)	NC score	0.342237 (rank : 478)
Query Neighborhood Hits	1371	Target Neighborhood Hits	960	Shared Neighborhood Hits	563
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

CALL3_HUMAN
θ value	0.0252991 (rank : 673)	NC score	0.040029 (rank : 2217)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	47
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

DIAP3_HUMAN
θ value	0.0252991 (rank : 674)	NC score	0.059981 (rank : 1886)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

DNJC8_HUMAN
θ value	0.0252991 (rank : 675)	NC score	0.128716 (rank : 1247)
Query Neighborhood Hits	1371	Target Neighborhood Hits	380	Shared Neighborhood Hits	181
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	0.0252991 (rank : 676)	NC score	0.138018 (rank : 1176)
Query Neighborhood Hits	1371	Target Neighborhood Hits	392	Shared Neighborhood Hits	193
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

EVPL_MOUSE
θ value	0.0252991 (rank : 677)	NC score	0.446356 (rank : 222)
Query Neighborhood Hits	1371	Target Neighborhood Hits	952	Shared Neighborhood Hits	610
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

KI21B_HUMAN
θ value	0.0252991 (rank : 678)	NC score	0.254176 (rank : 679)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1017	Shared Neighborhood Hits	501
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

KI21B_MOUSE
θ value	0.0252991 (rank : 679)	NC score	0.254498 (rank : 677)
Query Neighborhood Hits	1371	Target Neighborhood Hits	997	Shared Neighborhood Hits	495
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

KNTC2_HUMAN
θ value	0.0252991 (rank : 680)	NC score	0.437636 (rank : 242)
Query Neighborhood Hits	1371	Target Neighborhood Hits	673	Shared Neighborhood Hits	483
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

LAD1_HUMAN
θ value	0.0252991 (rank : 681)	NC score	0.046664 (rank : 2192)
Query Neighborhood Hits	1371	Target Neighborhood Hits	441	Shared Neighborhood Hits	91
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

NEB2_HUMAN
θ value	0.0252991 (rank : 682)	NC score	0.335820 (rank : 492)
Query Neighborhood Hits	1371	Target Neighborhood Hits	883	Shared Neighborhood Hits	524
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	0.0252991 (rank : 683)	NC score	0.345398 (rank : 477)
Query Neighborhood Hits	1371	Target Neighborhood Hits	889	Shared Neighborhood Hits	535
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NFH_HUMAN
θ value	0.0252991 (rank : 684)	NC score	0.196939 (rank : 853)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1242	Shared Neighborhood Hits	491
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NUF2_HUMAN
θ value	0.0252991 (rank : 685)	NC score	0.430248 (rank : 270)
Query Neighborhood Hits	1371	Target Neighborhood Hits	661	Shared Neighborhood Hits	461
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

NUF2_MOUSE
θ value	0.0252991 (rank : 686)	NC score	0.410015 (rank : 326)
Query Neighborhood Hits	1371	Target Neighborhood Hits	585	Shared Neighborhood Hits	430
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

PA24B_MOUSE
θ value	0.0252991 (rank : 687)	NC score	0.123869 (rank : 1275)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	75
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PEX13_HUMAN
θ value	0.0252991 (rank : 688)	NC score	0.249175 (rank : 698)
Query Neighborhood Hits	1371	Target Neighborhood Hits	128	Shared Neighborhood Hits	116
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

SHAN2_MOUSE
θ value	0.0252991 (rank : 689)	NC score	0.185946 (rank : 896)
Query Neighborhood Hits	1371	Target Neighborhood Hits	446	Shared Neighborhood Hits	154
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

STS1_MOUSE
θ value	0.0252991 (rank : 690)	NC score	0.146799 (rank : 1121)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

SYT10_HUMAN
θ value	0.0252991 (rank : 691)	NC score	0.162649 (rank : 1023)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	84
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYTL4_MOUSE
θ value	0.0252991 (rank : 692)	NC score	0.143837 (rank : 1137)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

T3JAM_HUMAN
θ value	0.0252991 (rank : 693)	NC score	0.387905 (rank : 387)
Query Neighborhood Hits	1371	Target Neighborhood Hits	533	Shared Neighborhood Hits	400
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

ANR18_HUMAN
θ value	0.0330416 (rank : 694)	NC score	0.317864 (rank : 526)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1106	Shared Neighborhood Hits	571
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CJ068_HUMAN
θ value	0.0330416 (rank : 695)	NC score	0.248901 (rank : 699)
Query Neighborhood Hits	1371	Target Neighborhood Hits	316	Shared Neighborhood Hits	194
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

DYNA_MOUSE
θ value	0.0330416 (rank : 696)	NC score	0.448451 (rank : 211)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1084	Shared Neighborhood Hits	633
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

EFS_HUMAN
θ value	0.0330416 (rank : 697)	NC score	0.258115 (rank : 662)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	176
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

MORC3_HUMAN
θ value	0.0330416 (rank : 698)	NC score	0.302115 (rank : 558)
Query Neighborhood Hits	1371	Target Neighborhood Hits	489	Shared Neighborhood Hits	369
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

MYO10_HUMAN
θ value	0.0330416 (rank : 699)	NC score	0.276059 (rank : 621)
Query Neighborhood Hits	1371	Target Neighborhood Hits	920	Shared Neighborhood Hits	557
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PLSI_HUMAN
θ value	0.0330416 (rank : 700)	NC score	0.068180 (rank : 1775)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	58
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

SPN90_HUMAN
θ value	0.0330416 (rank : 701)	NC score	0.186745 (rank : 892)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

STS1_HUMAN
θ value	0.0330416 (rank : 702)	NC score	0.146051 (rank : 1124)
Query Neighborhood Hits	1371	Target Neighborhood Hits	106	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

TARA_HUMAN
θ value	0.0330416 (rank : 703)	NC score	0.233163 (rank : 744)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1626	Shared Neighborhood Hits	478
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TMCO3_HUMAN
θ value	0.0330416 (rank : 704)	NC score	0.171256 (rank : 978)
Query Neighborhood Hits	1371	Target Neighborhood Hits	238	Shared Neighborhood Hits	192
SwissProt Accessions	Q6UWJ1, Q5JSB1, Q6NUN1, Q8NG29, Q8TCI6, Q96EA6, Q9NWT2	Gene names	TMCO3, C13orf11
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domain-containing protein 3 precursor (Putative LAG1-interacting protein).

CAR10_HUMAN
θ value	0.0431538 (rank : 705)	NC score	0.341412 (rank : 480)
Query Neighborhood Hits	1371	Target Neighborhood Hits	569	Shared Neighborhood Hits	416
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CCD91_HUMAN
θ value	0.0431538 (rank : 706)	NC score	0.441886 (rank : 233)
Query Neighborhood Hits	1371	Target Neighborhood Hits	868	Shared Neighborhood Hits	560
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CENPJ_HUMAN
θ value	0.0431538 (rank : 707)	NC score	0.368830 (rank : 424)
Query Neighborhood Hits	1371	Target Neighborhood Hits	721	Shared Neighborhood Hits	469
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CSKP_MOUSE
θ value	0.0431538 (rank : 708)	NC score	0.081651 (rank : 1620)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1027	Shared Neighborhood Hits	205
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CTGE6_HUMAN
θ value	0.0431538 (rank : 709)	NC score	0.359050 (rank : 449)
Query Neighborhood Hits	1371	Target Neighborhood Hits	650	Shared Neighborhood Hits	444
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

DAPK3_HUMAN
θ value	0.0431538 (rank : 710)	NC score	0.054962 (rank : 1989)
Query Neighborhood Hits	1371	Target Neighborhood Hits	945	Shared Neighborhood Hits	187
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

EMIL1_HUMAN
θ value	0.0431538 (rank : 711)	NC score	0.038701 (rank : 2219)
Query Neighborhood Hits	1371	Target Neighborhood Hits	239	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

GLE1_HUMAN
θ value	0.0431538 (rank : 712)	NC score	0.282499 (rank : 603)
Query Neighborhood Hits	1371	Target Neighborhood Hits	445	Shared Neighborhood Hits	321
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

KIF11_MOUSE
θ value	0.0431538 (rank : 713)	NC score	0.216448 (rank : 799)
Query Neighborhood Hits	1371	Target Neighborhood Hits	446	Shared Neighborhood Hits	327
SwissProt Accessions	Q6P9P6, Q9Z1J0	Gene names	Kif11
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5).

PININ_HUMAN
θ value	0.0431538 (rank : 714)	NC score	0.363690 (rank : 436)
Query Neighborhood Hits	1371	Target Neighborhood Hits	753	Shared Neighborhood Hits	446
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	0.0431538 (rank : 715)	NC score	0.353834 (rank : 461)
Query Neighborhood Hits	1371	Target Neighborhood Hits	777	Shared Neighborhood Hits	437
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PTK6_HUMAN
θ value	0.0431538 (rank : 716)	NC score	0.116458 (rank : 1330)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1020	Shared Neighborhood Hits	234
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

SPTB2_HUMAN
θ value	0.0431538 (rank : 717)	NC score	0.295458 (rank : 576)
Query Neighborhood Hits	1371	Target Neighborhood Hits	748	Shared Neighborhood Hits	467
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

TEX9_HUMAN
θ value	0.0431538 (rank : 718)	NC score	0.392223 (rank : 379)
Query Neighborhood Hits	1371	Target Neighborhood Hits	541	Shared Neighborhood Hits	405
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

A20A2_HUMAN
θ value	0.0563607 (rank : 719)	NC score	0.218214 (rank : 794)
Query Neighborhood Hits	1371	Target Neighborhood Hits	716	Shared Neighborhood Hits	362
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ARI4A_HUMAN
θ value	0.0563607 (rank : 720)	NC score	0.164682 (rank : 1013)
Query Neighborhood Hits	1371	Target Neighborhood Hits	434	Shared Neighborhood Hits	204
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BAIP3_MOUSE
θ value	0.0563607 (rank : 721)	NC score	0.144382 (rank : 1134)
Query Neighborhood Hits	1371	Target Neighborhood Hits	112	Shared Neighborhood Hits	81
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BICD1_HUMAN
θ value	0.0563607 (rank : 722)	NC score	0.447983 (rank : 215)
Query Neighborhood Hits	1371	Target Neighborhood Hits	844	Shared Neighborhood Hits	565
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
θ value	0.0563607 (rank : 723)	NC score	0.454138 (rank : 194)
Query Neighborhood Hits	1371	Target Neighborhood Hits	837	Shared Neighborhood Hits	571
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BPAEA_HUMAN
θ value	0.0563607 (rank : 724)	NC score	0.387939 (rank : 386)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1369	Shared Neighborhood Hits	682
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CA065_HUMAN
θ value	0.0563607 (rank : 725)	NC score	0.378961 (rank : 407)
Query Neighborhood Hits	1371	Target Neighborhood Hits	469	Shared Neighborhood Hits	353
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CGAT2_HUMAN
θ value	0.0563607 (rank : 726)	NC score	0.021405 (rank : 2283)
Query Neighborhood Hits	1371	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N6G5, Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6	Gene names	GALNACT2, CHGN2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CTGE4_HUMAN
θ value	0.0563607 (rank : 727)	NC score	0.222019 (rank : 779)
Query Neighborhood Hits	1371	Target Neighborhood Hits	393	Shared Neighborhood Hits	277
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

DYNA_HUMAN
θ value	0.0563607 (rank : 728)	NC score	0.450205 (rank : 208)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1194	Shared Neighborhood Hits	662
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

EVG1_MOUSE
θ value	0.0563607 (rank : 729)	NC score	0.059939 (rank : 1887)
Query Neighborhood Hits	1371	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D9S1	Gene names
Domain Architecture
Description	UPF0193 protein EVG1 homolog.

EXOC1_HUMAN
θ value	0.0563607 (rank : 730)	NC score	0.137405 (rank : 1179)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NV70, Q8WUE7, Q96T15, Q9NZE4	Gene names	EXOC1, SEC3, SEC3L1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

KIF3A_HUMAN
θ value	0.0563607 (rank : 731)	NC score	0.261165 (rank : 655)
Query Neighborhood Hits	1371	Target Neighborhood Hits	704	Shared Neighborhood Hits	504
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

NUCB2_MOUSE
θ value	0.0563607 (rank : 732)	NC score	0.251277 (rank : 693)
Query Neighborhood Hits	1371	Target Neighborhood Hits	459	Shared Neighborhood Hits	311
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

PA24F_HUMAN
θ value	0.0563607 (rank : 733)	NC score	0.088734 (rank : 1554)
Query Neighborhood Hits	1371	Target Neighborhood Hits	78	Shared Neighborhood Hits	68
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

RPGR1_HUMAN
θ value	0.0563607 (rank : 734)	NC score	0.384487 (rank : 396)
Query Neighborhood Hits	1371	Target Neighborhood Hits	578	Shared Neighborhood Hits	403
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RUSC2_MOUSE
θ value	0.0563607 (rank : 735)	NC score	0.108156 (rank : 1393)
Query Neighborhood Hits	1371	Target Neighborhood Hits	305	Shared Neighborhood Hits	87
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SKIL_MOUSE
θ value	0.0563607 (rank : 736)	NC score	0.340813 (rank : 482)
Query Neighborhood Hits	1371	Target Neighborhood Hits	719	Shared Neighborhood Hits	506
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SMC2_MOUSE
θ value	0.0563607 (rank : 737)	NC score	0.456987 (rank : 186)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1131	Shared Neighborhood Hits	676
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SNX18_HUMAN
θ value	0.0563607 (rank : 738)	NC score	0.211260 (rank : 814)
Query Neighborhood Hits	1371	Target Neighborhood Hits	207	Shared Neighborhood Hits	143
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

TARA_MOUSE
θ value	0.0563607 (rank : 739)	NC score	0.268595 (rank : 639)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1133	Shared Neighborhood Hits	429
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRAK1_HUMAN
θ value	0.0563607 (rank : 740)	NC score	0.407811 (rank : 328)
Query Neighborhood Hits	1371	Target Neighborhood Hits	660	Shared Neighborhood Hits	466
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

UBXD2_HUMAN
θ value	0.0563607 (rank : 741)	NC score	0.158545 (rank : 1047)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	169
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

UTP11_HUMAN
θ value	0.0563607 (rank : 742)	NC score	0.098149 (rank : 1475)
Query Neighborhood Hits	1371	Target Neighborhood Hits	99	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y3A2, Q5VT93, Q9BS98, Q9NS31	Gene names	UTP11L
Domain Architecture
Description	Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA- associated protein 11) (UTP11-like protein).

ACTN3_MOUSE
θ value	0.0736092 (rank : 743)	NC score	0.092925 (rank : 1515)
Query Neighborhood Hits	1371	Target Neighborhood Hits	265	Shared Neighborhood Hits	159
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ADIP_HUMAN
θ value	0.0736092 (rank : 744)	NC score	0.355169 (rank : 458)
Query Neighborhood Hits	1371	Target Neighborhood Hits	470	Shared Neighborhood Hits	379
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

C102B_HUMAN
θ value	0.0736092 (rank : 745)	NC score	0.415679 (rank : 312)
Query Neighborhood Hits	1371	Target Neighborhood Hits	542	Shared Neighborhood Hits	409
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CALL5_HUMAN
θ value	0.0736092 (rank : 746)	NC score	0.058039 (rank : 1924)
Query Neighborhood Hits	1371	Target Neighborhood Hits	231	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CCD42_MOUSE
θ value	0.0736092 (rank : 747)	NC score	0.278210 (rank : 616)
Query Neighborhood Hits	1371	Target Neighborhood Hits	284	Shared Neighborhood Hits	244
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CEP35_HUMAN
θ value	0.0736092 (rank : 748)	NC score	0.316658 (rank : 532)
Query Neighborhood Hits	1371	Target Neighborhood Hits	811	Shared Neighborhood Hits	443
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CHMP6_HUMAN
θ value	0.0736092 (rank : 749)	NC score	0.116637 (rank : 1327)
Query Neighborhood Hits	1371	Target Neighborhood Hits	92	Shared Neighborhood Hits	66
SwissProt Accessions	Q96FZ7, Q53FU4, Q9HAE8	Gene names	CHMP6, VPS20
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6) (Vacuolar protein sorting-associated protein 20) (hVps20).

CHMP6_MOUSE
θ value	0.0736092 (rank : 750)	NC score	0.100176 (rank : 1462)
Query Neighborhood Hits	1371	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	P0C0A3	Gene names	Chmp6
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6).

CN145_MOUSE
θ value	0.0736092 (rank : 751)	NC score	0.480187 (rank : 143)
Query Neighborhood Hits	1371	Target Neighborhood Hits	916	Shared Neighborhood Hits	596
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CTGE5_MOUSE
θ value	0.0736092 (rank : 752)	NC score	0.423476 (rank : 288)
Query Neighborhood Hits	1371	Target Neighborhood Hits	928	Shared Neighborhood Hits	586
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

EBP2_HUMAN
θ value	0.0736092 (rank : 753)	NC score	0.070956 (rank : 1741)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	Q99848, Q96A66	Gene names	EBNA1BP2, EBP2
Domain Architecture
Description	Probable rRNA-processing protein EBP2 (EBNA1-binding protein 2) (Nucleolar protein p40).

ENAH_MOUSE
θ value	0.0736092 (rank : 754)	NC score	0.222810 (rank : 775)
Query Neighborhood Hits	1371	Target Neighborhood Hits	919	Shared Neighborhood Hits	388
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EZRI_MOUSE
θ value	0.0736092 (rank : 755)	NC score	0.286377 (rank : 589)
Query Neighborhood Hits	1371	Target Neighborhood Hits	693	Shared Neighborhood Hits	508
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

GLE1_MOUSE
θ value	0.0736092 (rank : 756)	NC score	0.301354 (rank : 560)
Query Neighborhood Hits	1371	Target Neighborhood Hits	504	Shared Neighborhood Hits	370
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

IF2P_HUMAN
θ value	0.0736092 (rank : 757)	NC score	0.362993 (rank : 439)
Query Neighborhood Hits	1371	Target Neighborhood Hits	889	Shared Neighborhood Hits	493
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

K1HA_HUMAN
θ value	0.0736092 (rank : 758)	NC score	0.209698 (rank : 824)
Query Neighborhood Hits	1371	Target Neighborhood Hits	502	Shared Neighborhood Hits	378
SwissProt Accessions	O76009	Gene names	KRTHA3A, HHA3-I, HKA3A
Domain Architecture
Description	Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I).

MINK1_HUMAN
θ value	0.0736092 (rank : 759)	NC score	0.132506 (rank : 1213)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1477	Shared Neighborhood Hits	507
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MPP2_HUMAN
θ value	0.0736092 (rank : 760)	NC score	0.107559 (rank : 1402)
Query Neighborhood Hits	1371	Target Neighborhood Hits	173	Shared Neighborhood Hits	87
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	0.0736092 (rank : 761)	NC score	0.108299 (rank : 1392)
Query Neighborhood Hits	1371	Target Neighborhood Hits	189	Shared Neighborhood Hits	88
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

NPBL_MOUSE
θ value	0.0736092 (rank : 762)	NC score	0.080460 (rank : 1629)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1041	Shared Neighborhood Hits	230
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RASF8_MOUSE
θ value	0.0736092 (rank : 763)	NC score	0.326091 (rank : 509)
Query Neighborhood Hits	1371	Target Neighborhood Hits	391	Shared Neighborhood Hits	319
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

RIMS1_HUMAN
θ value	0.0736092 (rank : 764)	NC score	0.128129 (rank : 1252)
Query Neighborhood Hits	1371	Target Neighborhood Hits	437	Shared Neighborhood Hits	132
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SDPR_HUMAN
θ value	0.0736092 (rank : 765)	NC score	0.160912 (rank : 1031)
Query Neighborhood Hits	1371	Target Neighborhood Hits	337	Shared Neighborhood Hits	193
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SNX18_MOUSE
θ value	0.0736092 (rank : 766)	NC score	0.215311 (rank : 805)
Query Neighborhood Hits	1371	Target Neighborhood Hits	198	Shared Neighborhood Hits	139
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

STIM1_HUMAN
θ value	0.0736092 (rank : 767)	NC score	0.321566 (rank : 514)
Query Neighborhood Hits	1371	Target Neighborhood Hits	665	Shared Neighborhood Hits	455
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TAF4_HUMAN
θ value	0.0736092 (rank : 768)	NC score	0.108954 (rank : 1385)
Query Neighborhood Hits	1371	Target Neighborhood Hits	687	Shared Neighborhood Hits	193
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

UN13D_HUMAN
θ value	0.0736092 (rank : 769)	NC score	0.157595 (rank : 1056)
Query Neighborhood Hits	1371	Target Neighborhood Hits	117	Shared Neighborhood Hits	85
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

VDP_HUMAN
θ value	0.0736092 (rank : 770)	NC score	0.384772 (rank : 395)
Query Neighborhood Hits	1371	Target Neighborhood Hits	645	Shared Neighborhood Hits	425
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

A20A4_HUMAN
θ value	0.0961366 (rank : 771)	NC score	0.227021 (rank : 762)
Query Neighborhood Hits	1371	Target Neighborhood Hits	710	Shared Neighborhood Hits	364
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ABL2_HUMAN
θ value	0.0961366 (rank : 772)	NC score	0.110187 (rank : 1377)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1045	Shared Neighborhood Hits	198
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

AMPH_HUMAN
θ value	0.0961366 (rank : 773)	NC score	0.171694 (rank : 976)
Query Neighborhood Hits	1371	Target Neighborhood Hits	455	Shared Neighborhood Hits	192
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

BAZ1B_HUMAN
θ value	0.0961366 (rank : 774)	NC score	0.150179 (rank : 1095)
Query Neighborhood Hits	1371	Target Neighborhood Hits	701	Shared Neighborhood Hits	346
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CAF1A_HUMAN
θ value	0.0961366 (rank : 775)	NC score	0.369367 (rank : 421)
Query Neighborhood Hits	1371	Target Neighborhood Hits	750	Shared Neighborhood Hits	484
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCHCR_HUMAN
θ value	0.0961366 (rank : 776)	NC score	0.454035 (rank : 195)
Query Neighborhood Hits	1371	Target Neighborhood Hits	717	Shared Neighborhood Hits	505
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CENPK_HUMAN
θ value	0.0961366 (rank : 777)	NC score	0.242332 (rank : 721)
Query Neighborhood Hits	1371	Target Neighborhood Hits	273	Shared Neighborhood Hits	224
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

CRCM_HUMAN
θ value	0.0961366 (rank : 778)	NC score	0.392940 (rank : 377)
Query Neighborhood Hits	1371	Target Neighborhood Hits	520	Shared Neighborhood Hits	396
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

DDX23_HUMAN
θ value	0.0961366 (rank : 779)	NC score	0.083280 (rank : 1606)
Query Neighborhood Hits	1371	Target Neighborhood Hits	486	Shared Neighborhood Hits	284
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

EMIL1_MOUSE
θ value	0.0961366 (rank : 780)	NC score	0.034526 (rank : 2234)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	66
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

ES8L2_HUMAN
θ value	0.0961366 (rank : 781)	NC score	0.178885 (rank : 931)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	143
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

FYCO1_HUMAN
θ value	0.0961366 (rank : 782)	NC score	0.465512 (rank : 173)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1149	Shared Neighborhood Hits	652
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

HHEX_HUMAN
θ value	0.0961366 (rank : 783)	NC score	0.002835 (rank : 2333)
Query Neighborhood Hits	1371	Target Neighborhood Hits	358	Shared Neighborhood Hits	28
SwissProt Accessions	Q03014	Gene names	HHEX, HEX, PRH, PRHX
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

HSP76_HUMAN
θ value	0.0961366 (rank : 784)	NC score	0.023304 (rank : 2272)
Query Neighborhood Hits	1371	Target Neighborhood Hits	128	Shared Neighborhood Hits	79
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

ITK_MOUSE
θ value	0.0961366 (rank : 785)	NC score	0.108155 (rank : 1394)
Query Neighborhood Hits	1371	Target Neighborhood Hits	985	Shared Neighborhood Hits	196
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

K1C16_MOUSE
θ value	0.0961366 (rank : 786)	NC score	0.167413 (rank : 996)
Query Neighborhood Hits	1371	Target Neighborhood Hits	444	Shared Neighborhood Hits	338
SwissProt Accessions	Q9Z2K1	Gene names	Krt16, Krt1-16
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

LIPB2_MOUSE
θ value	0.0961366 (rank : 787)	NC score	0.320159 (rank : 520)
Query Neighborhood Hits	1371	Target Neighborhood Hits	570	Shared Neighborhood Hits	395
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

PA24A_MOUSE
θ value	0.0961366 (rank : 788)	NC score	0.106948 (rank : 1408)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

SAS6_HUMAN
θ value	0.0961366 (rank : 789)	NC score	0.456618 (rank : 189)
Query Neighborhood Hits	1371	Target Neighborhood Hits	791	Shared Neighborhood Hits	541
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SDCG8_MOUSE
θ value	0.0961366 (rank : 790)	NC score	0.469544 (rank : 168)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	598
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SLAP2_HUMAN
θ value	0.0961366 (rank : 791)	NC score	0.181582 (rank : 915)
Query Neighborhood Hits	1371	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

STABP_MOUSE
θ value	0.0961366 (rank : 792)	NC score	0.107894 (rank : 1397)
Query Neighborhood Hits	1371	Target Neighborhood Hits	191	Shared Neighborhood Hits	144
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

STMN2_HUMAN
θ value	0.0961366 (rank : 793)	NC score	0.245940 (rank : 708)
Query Neighborhood Hits	1371	Target Neighborhood Hits	458	Shared Neighborhood Hits	325
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
θ value	0.0961366 (rank : 794)	NC score	0.245940 (rank : 709)
Query Neighborhood Hits	1371	Target Neighborhood Hits	458	Shared Neighborhood Hits	325
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STX3_HUMAN
θ value	0.0961366 (rank : 795)	NC score	0.106738 (rank : 1412)
Query Neighborhood Hits	1371	Target Neighborhood Hits	211	Shared Neighborhood Hits	160
SwissProt Accessions	Q13277, O43750, O43751, Q15360	Gene names	STX3, STX3A
Domain Architecture
Description	Syntaxin-3.

STX3_MOUSE
θ value	0.0961366 (rank : 796)	NC score	0.104818 (rank : 1426)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	162
SwissProt Accessions	Q64704	Gene names	Stx3, Stx3a
Domain Architecture
Description	Syntaxin-3.

SYTL1_HUMAN
θ value	0.0961366 (rank : 797)	NC score	0.133109 (rank : 1210)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

TLK2_HUMAN
θ value	0.0961366 (rank : 798)	NC score	0.083434 (rank : 1603)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1044	Shared Neighborhood Hits	270
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TNNT2_MOUSE
θ value	0.0961366 (rank : 799)	NC score	0.279636 (rank : 609)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	288
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TRAF3_HUMAN
θ value	0.0961366 (rank : 800)	NC score	0.142862 (rank : 1143)
Query Neighborhood Hits	1371	Target Neighborhood Hits	463	Shared Neighborhood Hits	265
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	0.0961366 (rank : 801)	NC score	0.145146 (rank : 1129)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	266
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRI62_MOUSE
θ value	0.0961366 (rank : 802)	NC score	0.064134 (rank : 1821)
Query Neighborhood Hits	1371	Target Neighborhood Hits	478	Shared Neighborhood Hits	221
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM8_HUMAN
θ value	0.0961366 (rank : 803)	NC score	0.128051 (rank : 1253)
Query Neighborhood Hits	1371	Target Neighborhood Hits	650	Shared Neighborhood Hits	299
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BAG1_HUMAN
θ value	0.125558 (rank : 804)	NC score	0.084252 (rank : 1591)
Query Neighborhood Hits	1371	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q99933, O75315, Q14414, Q9Y2V4	Gene names	BAG1
Domain Architecture
Description	BAG family molecular chaperone regulator 1 (BCL-2-binding athanogene- 1) (BAG-1) (Glucocorticoid receptor-associated protein RAP46).

BFSP2_HUMAN
θ value	0.125558 (rank : 805)	NC score	0.156897 (rank : 1061)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	264
SwissProt Accessions	Q13515, Q9HBW5	Gene names	BFSP2
Domain Architecture
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein) (CP 47) (CP47) (Lens intermediate filament-like light) (LIFL-L).

CCD11_HUMAN
θ value	0.125558 (rank : 806)	NC score	0.465294 (rank : 175)
Query Neighborhood Hits	1371	Target Neighborhood Hits	822	Shared Neighborhood Hits	580
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CJ078_MOUSE
θ value	0.125558 (rank : 807)	NC score	0.067705 (rank : 1783)
Query Neighborhood Hits	1371	Target Neighborhood Hits	559	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

DOCK1_HUMAN
θ value	0.125558 (rank : 808)	NC score	0.115577 (rank : 1337)
Query Neighborhood Hits	1371	Target Neighborhood Hits	191	Shared Neighborhood Hits	126
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DYXC1_HUMAN
θ value	0.125558 (rank : 809)	NC score	0.094639 (rank : 1500)
Query Neighborhood Hits	1371	Target Neighborhood Hits	261	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

JIP3_MOUSE
θ value	0.125558 (rank : 810)	NC score	0.279230 (rank : 611)
Query Neighborhood Hits	1371	Target Neighborhood Hits	759	Shared Neighborhood Hits	492
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

K1H8_HUMAN
θ value	0.125558 (rank : 811)	NC score	0.150221 (rank : 1094)
Query Neighborhood Hits	1371	Target Neighborhood Hits	394	Shared Neighborhood Hits	295
SwissProt Accessions	O76015	Gene names	KRTHA8, HHA8, HKA8
Domain Architecture
Description	Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8).

KIF3A_MOUSE
θ value	0.125558 (rank : 812)	NC score	0.263717 (rank : 651)
Query Neighborhood Hits	1371	Target Neighborhood Hits	715	Shared Neighborhood Hits	511
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MPP9_HUMAN
θ value	0.125558 (rank : 813)	NC score	0.385467 (rank : 394)
Query Neighborhood Hits	1371	Target Neighborhood Hits	529	Shared Neighborhood Hits	386
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

PLVAP_HUMAN
θ value	0.125558 (rank : 814)	NC score	0.301727 (rank : 559)
Query Neighborhood Hits	1371	Target Neighborhood Hits	397	Shared Neighborhood Hits	313
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

STMN3_MOUSE
θ value	0.125558 (rank : 815)	NC score	0.218937 (rank : 791)
Query Neighborhood Hits	1371	Target Neighborhood Hits	331	Shared Neighborhood Hits	270
SwissProt Accessions	O70166	Gene names	Stmn3, Sclip
Domain Architecture
Description	Stathmin-3 (SCG10-like protein) (SCG10-related protein HiAT3) (Hippocampus abundant transcript 3).

TEKT1_MOUSE
θ value	0.125558 (rank : 816)	NC score	0.289101 (rank : 585)
Query Neighborhood Hits	1371	Target Neighborhood Hits	399	Shared Neighborhood Hits	303
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

TRIM7_HUMAN
θ value	0.125558 (rank : 817)	NC score	0.030609 (rank : 2251)
Query Neighborhood Hits	1371	Target Neighborhood Hits	336	Shared Neighborhood Hits	108
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

ZWINT_HUMAN
θ value	0.125558 (rank : 818)	NC score	0.280012 (rank : 608)
Query Neighborhood Hits	1371	Target Neighborhood Hits	333	Shared Neighborhood Hits	265
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

AFAD_HUMAN
θ value	0.163984 (rank : 819)	NC score	0.238016 (rank : 731)
Query Neighborhood Hits	1371	Target Neighborhood Hits	689	Shared Neighborhood Hits	353
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ANR12_HUMAN
θ value	0.163984 (rank : 820)	NC score	0.221152 (rank : 784)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1081	Shared Neighborhood Hits	425
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ATRX_HUMAN
θ value	0.163984 (rank : 821)	NC score	0.160666 (rank : 1033)
Query Neighborhood Hits	1371	Target Neighborhood Hits	842	Shared Neighborhood Hits	354
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BFSP1_HUMAN
θ value	0.163984 (rank : 822)	NC score	0.280827 (rank : 605)
Query Neighborhood Hits	1371	Target Neighborhood Hits	508	Shared Neighborhood Hits	386
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

CANB2_MOUSE
θ value	0.163984 (rank : 823)	NC score	0.041904 (rank : 2211)
Query Neighborhood Hits	1371	Target Neighborhood Hits	173	Shared Neighborhood Hits	39
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CDC37_MOUSE
θ value	0.163984 (rank : 824)	NC score	0.258447 (rank : 661)
Query Neighborhood Hits	1371	Target Neighborhood Hits	359	Shared Neighborhood Hits	289
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CDR2_MOUSE
θ value	0.163984 (rank : 825)	NC score	0.365378 (rank : 431)
Query Neighborhood Hits	1371	Target Neighborhood Hits	482	Shared Neighborhood Hits	373
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CIP4_HUMAN
θ value	0.163984 (rank : 826)	NC score	0.309127 (rank : 544)
Query Neighborhood Hits	1371	Target Neighborhood Hits	374	Shared Neighborhood Hits	304
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

EBP2_MOUSE
θ value	0.163984 (rank : 827)	NC score	0.073404 (rank : 1712)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D903, Q3TKB5	Gene names	Ebna1bp2, Ebp2
Domain Architecture
Description	Probable rRNA-processing protein EBP2.

GABP2_MOUSE
θ value	0.163984 (rank : 828)	NC score	0.050114 (rank : 2178)
Query Neighborhood Hits	1371	Target Neighborhood Hits	429	Shared Neighborhood Hits	128
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

GOG8A_HUMAN
θ value	0.163984 (rank : 829)	NC score	0.422026 (rank : 292)
Query Neighborhood Hits	1371	Target Neighborhood Hits	635	Shared Neighborhood Hits	463
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

IF4G3_HUMAN
θ value	0.163984 (rank : 830)	NC score	0.059332 (rank : 1894)
Query Neighborhood Hits	1371	Target Neighborhood Hits	247	Shared Neighborhood Hits	99
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

KI13A_HUMAN
θ value	0.163984 (rank : 831)	NC score	0.121416 (rank : 1289)
Query Neighborhood Hits	1371	Target Neighborhood Hits	359	Shared Neighborhood Hits	232
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

MAP1A_HUMAN
θ value	0.163984 (rank : 832)	NC score	0.345963 (rank : 476)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1626	Shared Neighborhood Hits	600
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

STIM1_MOUSE
θ value	0.163984 (rank : 833)	NC score	0.318391 (rank : 523)
Query Neighborhood Hits	1371	Target Neighborhood Hits	660	Shared Neighborhood Hits	457
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SYGP1_HUMAN
θ value	0.163984 (rank : 834)	NC score	0.208107 (rank : 825)
Query Neighborhood Hits	1371	Target Neighborhood Hits	589	Shared Neighborhood Hits	398
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

TNNI2_HUMAN
θ value	0.163984 (rank : 835)	NC score	0.073020 (rank : 1715)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	P48788	Gene names	TNNI2
Domain Architecture
Description	Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).

TRAIP_MOUSE
θ value	0.163984 (rank : 836)	NC score	0.405015 (rank : 342)
Query Neighborhood Hits	1371	Target Neighborhood Hits	745	Shared Neighborhood Hits	450
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI35_MOUSE
θ value	0.163984 (rank : 837)	NC score	0.062171 (rank : 1850)
Query Neighborhood Hits	1371	Target Neighborhood Hits	465	Shared Neighborhood Hits	187
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRIM8_MOUSE
θ value	0.163984 (rank : 838)	NC score	0.127449 (rank : 1256)
Query Neighborhood Hits	1371	Target Neighborhood Hits	674	Shared Neighborhood Hits	317
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

XE7_HUMAN
θ value	0.163984 (rank : 839)	NC score	0.461377 (rank : 180)
Query Neighborhood Hits	1371	Target Neighborhood Hits	738	Shared Neighborhood Hits	524
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

A20A1_HUMAN
θ value	0.21417 (rank : 840)	NC score	0.219028 (rank : 789)
Query Neighborhood Hits	1371	Target Neighborhood Hits	698	Shared Neighborhood Hits	354
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

CPNE3_MOUSE
θ value	0.21417 (rank : 841)	NC score	0.065351 (rank : 1809)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

ES8L2_MOUSE
θ value	0.21417 (rank : 842)	NC score	0.175172 (rank : 952)
Query Neighborhood Hits	1371	Target Neighborhood Hits	169	Shared Neighborhood Hits	138
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

GBP4_HUMAN
θ value	0.21417 (rank : 843)	NC score	0.217406 (rank : 796)
Query Neighborhood Hits	1371	Target Neighborhood Hits	484	Shared Neighborhood Hits	354
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

IF4G3_MOUSE
θ value	0.21417 (rank : 844)	NC score	0.050799 (rank : 2154)
Query Neighborhood Hits	1371	Target Neighborhood Hits	279	Shared Neighborhood Hits	99
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K0831_MOUSE
θ value	0.21417 (rank : 845)	NC score	0.191473 (rank : 875)
Query Neighborhood Hits	1371	Target Neighborhood Hits	277	Shared Neighborhood Hits	216
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

K1C15_MOUSE
θ value	0.21417 (rank : 846)	NC score	0.172142 (rank : 971)
Query Neighborhood Hits	1371	Target Neighborhood Hits	429	Shared Neighborhood Hits	325
SwissProt Accessions	Q61414, Q6PEQ0	Gene names	Krt15, Krt1-15
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

K1H4_HUMAN
θ value	0.21417 (rank : 847)	NC score	0.199460 (rank : 844)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	355
SwissProt Accessions	O76011	Gene names	KRTHA4, HHA4, HKA4
Domain Architecture
Description	Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4).

LRRF2_MOUSE
θ value	0.21417 (rank : 848)	NC score	0.400907 (rank : 353)
Query Neighborhood Hits	1371	Target Neighborhood Hits	556	Shared Neighborhood Hits	406
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MACOI_MOUSE
θ value	0.21417 (rank : 849)	NC score	0.405481 (rank : 339)
Query Neighborhood Hits	1371	Target Neighborhood Hits	620	Shared Neighborhood Hits	448
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MED4_MOUSE
θ value	0.21417 (rank : 850)	NC score	0.114699 (rank : 1346)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CQA5	Gene names	Med4, Vdrip
Domain Architecture	No domain graphic available
Description	Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4).

METL4_HUMAN
θ value	0.21417 (rank : 851)	NC score	0.022394 (rank : 2278)
Query Neighborhood Hits	1371	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N3J2, Q2TAA7, Q9H5U9	Gene names	METTL4
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 4 (EC 2.1.1.-).

MINK1_MOUSE
θ value	0.21417 (rank : 852)	NC score	0.131792 (rank : 1223)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1451	Shared Neighborhood Hits	502
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINT_HUMAN
θ value	0.21417 (rank : 853)	NC score	0.148594 (rank : 1101)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1291	Shared Neighborhood Hits	327
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MRCKG_HUMAN
θ value	0.21417 (rank : 854)	NC score	0.172587 (rank : 969)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1519	Shared Neighborhood Hits	542
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

N4BP3_HUMAN
θ value	0.21417 (rank : 855)	NC score	0.165355 (rank : 1007)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	120
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

N4BP3_MOUSE
θ value	0.21417 (rank : 856)	NC score	0.192753 (rank : 871)
Query Neighborhood Hits	1371	Target Neighborhood Hits	179	Shared Neighborhood Hits	144
SwissProt Accessions	Q8C7U1, Q3TDC7, Q7TNR2, Q922W0, Q99J06	Gene names	N4bp3
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

P85A_HUMAN
θ value	0.21417 (rank : 857)	NC score	0.235898 (rank : 738)
Query Neighborhood Hits	1371	Target Neighborhood Hits	479	Shared Neighborhood Hits	312
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	0.21417 (rank : 858)	NC score	0.278912 (rank : 613)
Query Neighborhood Hits	1371	Target Neighborhood Hits	543	Shared Neighborhood Hits	357
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PHLB1_HUMAN
θ value	0.21417 (rank : 859)	NC score	0.311165 (rank : 539)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1038	Shared Neighborhood Hits	484
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRC1_MOUSE
θ value	0.21417 (rank : 860)	NC score	0.279066 (rank : 612)
Query Neighborhood Hits	1371	Target Neighborhood Hits	382	Shared Neighborhood Hits	303
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

RASF8_HUMAN
θ value	0.21417 (rank : 861)	NC score	0.351450 (rank : 466)
Query Neighborhood Hits	1371	Target Neighborhood Hits	469	Shared Neighborhood Hits	364
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

SHLB2_HUMAN
θ value	0.21417 (rank : 862)	NC score	0.149259 (rank : 1098)
Query Neighborhood Hits	1371	Target Neighborhood Hits	86	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	0.21417 (rank : 863)	NC score	0.150118 (rank : 1096)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SMCE1_HUMAN
θ value	0.21417 (rank : 864)	NC score	0.144474 (rank : 1133)
Query Neighborhood Hits	1371	Target Neighborhood Hits	272	Shared Neighborhood Hits	144
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SPN90_MOUSE
θ value	0.21417 (rank : 865)	NC score	0.158719 (rank : 1046)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

TDRD7_HUMAN
θ value	0.21417 (rank : 866)	NC score	0.013919 (rank : 2303)
Query Neighborhood Hits	1371	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NHU6, Q96JT1, Q9UFF0, Q9Y2M3	Gene names	TDRD7, PCTAIRE2BP
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

TNNT2_HUMAN
θ value	0.21417 (rank : 867)	NC score	0.292528 (rank : 580)
Query Neighborhood Hits	1371	Target Neighborhood Hits	433	Shared Neighborhood Hits	310
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

ZN318_MOUSE
θ value	0.21417 (rank : 868)	NC score	0.176336 (rank : 942)
Query Neighborhood Hits	1371	Target Neighborhood Hits	642	Shared Neighborhood Hits	294
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

A16L1_HUMAN
θ value	0.279714 (rank : 869)	NC score	0.152477 (rank : 1085)
Query Neighborhood Hits	1371	Target Neighborhood Hits	664	Shared Neighborhood Hits	316
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

A16L1_MOUSE
θ value	0.279714 (rank : 870)	NC score	0.181533 (rank : 916)
Query Neighborhood Hits	1371	Target Neighborhood Hits	776	Shared Neighborhood Hits	382
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

A20A3_HUMAN
θ value	0.279714 (rank : 871)	NC score	0.218607 (rank : 792)
Query Neighborhood Hits	1371	Target Neighborhood Hits	692	Shared Neighborhood Hits	352
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

AMPH_MOUSE
θ value	0.279714 (rank : 872)	NC score	0.157284 (rank : 1060)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	154
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

AR13B_HUMAN
θ value	0.279714 (rank : 873)	NC score	0.087409 (rank : 1564)
Query Neighborhood Hits	1371	Target Neighborhood Hits	528	Shared Neighborhood Hits	238
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

BRE1A_MOUSE
θ value	0.279714 (rank : 874)	NC score	0.444932 (rank : 226)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1025	Shared Neighborhood Hits	604
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CAR14_MOUSE
θ value	0.279714 (rank : 875)	NC score	0.317820 (rank : 527)
Query Neighborhood Hits	1371	Target Neighborhood Hits	526	Shared Neighborhood Hits	397
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

CCD93_MOUSE
θ value	0.279714 (rank : 876)	NC score	0.304562 (rank : 551)
Query Neighborhood Hits	1371	Target Neighborhood Hits	362	Shared Neighborhood Hits	288
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CEP70_HUMAN
θ value	0.279714 (rank : 877)	NC score	0.350236 (rank : 470)
Query Neighborhood Hits	1371	Target Neighborhood Hits	432	Shared Neighborhood Hits	359
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

FYCO1_MOUSE
θ value	0.279714 (rank : 878)	NC score	0.474762 (rank : 157)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1059	Shared Neighborhood Hits	627
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GABP2_HUMAN
θ value	0.279714 (rank : 879)	NC score	0.052562 (rank : 2076)
Query Neighborhood Hits	1371	Target Neighborhood Hits	454	Shared Neighborhood Hits	144
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

HSP7C_HUMAN
θ value	0.279714 (rank : 880)	NC score	0.027446 (rank : 2261)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	81
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
θ value	0.279714 (rank : 881)	NC score	0.030770 (rank : 2249)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	95
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

INVO_MOUSE
θ value	0.279714 (rank : 882)	NC score	0.321299 (rank : 516)
Query Neighborhood Hits	1371	Target Neighborhood Hits	474	Shared Neighborhood Hits	284
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

LMNB1_MOUSE
θ value	0.279714 (rank : 883)	NC score	0.319143 (rank : 522)
Query Neighborhood Hits	1371	Target Neighborhood Hits	719	Shared Neighborhood Hits	499
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

OPA1_HUMAN
θ value	0.279714 (rank : 884)	NC score	0.034513 (rank : 2235)
Query Neighborhood Hits	1371	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

OVGP1_HUMAN
θ value	0.279714 (rank : 885)	NC score	0.006112 (rank : 2324)
Query Neighborhood Hits	1371	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

P85B_MOUSE
θ value	0.279714 (rank : 886)	NC score	0.270539 (rank : 636)
Query Neighborhood Hits	1371	Target Neighborhood Hits	519	Shared Neighborhood Hits	360
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PEG3_HUMAN
θ value	0.279714 (rank : 887)	NC score	-0.019534 (rank : 2354)
Query Neighborhood Hits	1371	Target Neighborhood Hits	800	Shared Neighborhood Hits	28
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

SEP11_MOUSE
θ value	0.279714 (rank : 888)	NC score	0.092084 (rank : 1526)
Query Neighborhood Hits	1371	Target Neighborhood Hits	300	Shared Neighborhood Hits	204
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

SEPT7_HUMAN
θ value	0.279714 (rank : 889)	NC score	0.128476 (rank : 1249)
Query Neighborhood Hits	1371	Target Neighborhood Hits	385	Shared Neighborhood Hits	289
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SMCE1_MOUSE
θ value	0.279714 (rank : 890)	NC score	0.168471 (rank : 992)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	186
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SPAG5_HUMAN
θ value	0.279714 (rank : 891)	NC score	0.390579 (rank : 383)
Query Neighborhood Hits	1371	Target Neighborhood Hits	625	Shared Neighborhood Hits	446
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

TEKT1_HUMAN
θ value	0.279714 (rank : 892)	NC score	0.254729 (rank : 676)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	251
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

USH1C_MOUSE
θ value	0.279714 (rank : 893)	NC score	0.143697 (rank : 1139)
Query Neighborhood Hits	1371	Target Neighborhood Hits	557	Shared Neighborhood Hits	261
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

CALN1_HUMAN
θ value	0.365318 (rank : 894)	NC score	0.048420 (rank : 2186)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
θ value	0.365318 (rank : 895)	NC score	0.048462 (rank : 2185)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CLCB_HUMAN
θ value	0.365318 (rank : 896)	NC score	0.075778 (rank : 1682)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	85
SwissProt Accessions	P09497, Q6FHW1	Gene names	CLTB
Domain Architecture
Description	Clathrin light chain B (Lcb).

CLCB_MOUSE
θ value	0.365318 (rank : 897)	NC score	0.080131 (rank : 1634)
Query Neighborhood Hits	1371	Target Neighborhood Hits	119	Shared Neighborhood Hits	83
SwissProt Accessions	Q6IRU5, Q8BR04, Q8CDX9, Q9CV35	Gene names	Cltb
Domain Architecture	No domain graphic available
Description	Clathrin light chain B (Lcb).

CM007_MOUSE
θ value	0.365318 (rank : 898)	NC score	0.147259 (rank : 1113)
Query Neighborhood Hits	1371	Target Neighborhood Hits	416	Shared Neighborhood Hits	178
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CPSF3_HUMAN
θ value	0.365318 (rank : 899)	NC score	0.028532 (rank : 2258)
Query Neighborhood Hits	1371	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKF6, O14769, Q96F36	Gene names	CPSF3, CPSF73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

CPSF3_MOUSE
θ value	0.365318 (rank : 900)	NC score	0.028569 (rank : 2256)
Query Neighborhood Hits	1371	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXK7	Gene names	Cpsf3, Cpsf73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

CREB3_HUMAN
θ value	0.365318 (rank : 901)	NC score	0.083355 (rank : 1605)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	83
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

CT096_HUMAN
θ value	0.365318 (rank : 902)	NC score	0.364520 (rank : 435)
Query Neighborhood Hits	1371	Target Neighborhood Hits	438	Shared Neighborhood Hits	326
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CTNA1_HUMAN
θ value	0.365318 (rank : 903)	NC score	0.032758 (rank : 2242)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	50
SwissProt Accessions	P35221, Q12795	Gene names	CTNNA1
Domain Architecture
Description	Catenin alpha-1 (Cadherin-associated protein) (Alpha E-catenin) (NY- REN-13 antigen).

CTNA1_MOUSE
θ value	0.365318 (rank : 904)	NC score	0.031037 (rank : 2246)
Query Neighborhood Hits	1371	Target Neighborhood Hits	84	Shared Neighborhood Hits	49
SwissProt Accessions	P26231	Gene names	Ctnna1, Catna1
Domain Architecture
Description	Catenin alpha-1 (102 kDa cadherin-associated protein) (CAP102) (Alpha E-catenin).

DAAM1_MOUSE
θ value	0.365318 (rank : 905)	NC score	0.155961 (rank : 1069)
Query Neighborhood Hits	1371	Target Neighborhood Hits	443	Shared Neighborhood Hits	284
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

ESCO1_HUMAN
θ value	0.365318 (rank : 906)	NC score	0.092875 (rank : 1516)
Query Neighborhood Hits	1371	Target Neighborhood Hits	361	Shared Neighborhood Hits	153
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

GCFC_HUMAN
θ value	0.365318 (rank : 907)	NC score	0.067046 (rank : 1794)
Query Neighborhood Hits	1371	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y5B6, Q9NYQ0	Gene names	GCFC, C21orf66
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor homolog.

HIP1R_HUMAN
θ value	0.365318 (rank : 908)	NC score	0.414573 (rank : 316)
Query Neighborhood Hits	1371	Target Neighborhood Hits	809	Shared Neighborhood Hits	539
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

KIF6_HUMAN
θ value	0.365318 (rank : 909)	NC score	0.135643 (rank : 1189)
Query Neighborhood Hits	1371	Target Neighborhood Hits	271	Shared Neighborhood Hits	199
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

KIFC3_HUMAN
θ value	0.365318 (rank : 910)	NC score	0.276138 (rank : 620)
Query Neighborhood Hits	1371	Target Neighborhood Hits	619	Shared Neighborhood Hits	456
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_MOUSE
θ value	0.365318 (rank : 911)	NC score	0.268037 (rank : 641)
Query Neighborhood Hits	1371	Target Neighborhood Hits	571	Shared Neighborhood Hits	420
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

LATS1_HUMAN
θ value	0.365318 (rank : 912)	NC score	0.051979 (rank : 2103)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1057	Shared Neighborhood Hits	159
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

MAP9_HUMAN
θ value	0.365318 (rank : 913)	NC score	0.297986 (rank : 570)
Query Neighborhood Hits	1371	Target Neighborhood Hits	518	Shared Neighborhood Hits	338
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MMRN1_HUMAN
θ value	0.365318 (rank : 914)	NC score	0.306224 (rank : 547)
Query Neighborhood Hits	1371	Target Neighborhood Hits	636	Shared Neighborhood Hits	313
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

NBR1_HUMAN
θ value	0.365318 (rank : 915)	NC score	0.037340 (rank : 2225)
Query Neighborhood Hits	1371	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

NFL_MOUSE
θ value	0.365318 (rank : 916)	NC score	0.204036 (rank : 834)
Query Neighborhood Hits	1371	Target Neighborhood Hits	695	Shared Neighborhood Hits	441
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NOL10_HUMAN
θ value	0.365318 (rank : 917)	NC score	0.151652 (rank : 1088)
Query Neighborhood Hits	1371	Target Neighborhood Hits	254	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NTBP1_MOUSE
θ value	0.365318 (rank : 918)	NC score	0.266623 (rank : 645)
Query Neighborhood Hits	1371	Target Neighborhood Hits	528	Shared Neighborhood Hits	296
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

OPA1_MOUSE
θ value	0.365318 (rank : 919)	NC score	0.030867 (rank : 2248)
Query Neighborhood Hits	1371	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

P85A_MOUSE
θ value	0.365318 (rank : 920)	NC score	0.221960 (rank : 781)
Query Neighborhood Hits	1371	Target Neighborhood Hits	435	Shared Neighborhood Hits	271
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SAFB1_HUMAN
θ value	0.365318 (rank : 921)	NC score	0.124773 (rank : 1270)
Query Neighborhood Hits	1371	Target Neighborhood Hits	493	Shared Neighborhood Hits	215
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

SASH1_HUMAN
θ value	0.365318 (rank : 922)	NC score	0.087160 (rank : 1566)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	87
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SEP11_HUMAN
θ value	0.365318 (rank : 923)	NC score	0.089369 (rank : 1546)
Query Neighborhood Hits	1371	Target Neighborhood Hits	296	Shared Neighborhood Hits	202
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

STABP_HUMAN
θ value	0.365318 (rank : 924)	NC score	0.085853 (rank : 1579)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	O95630, Q3MJE7	Gene names	STAMBP, AMSH
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

STMN3_HUMAN
θ value	0.365318 (rank : 925)	NC score	0.228826 (rank : 758)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	285
SwissProt Accessions	Q9NZ72, O75527, Q969Y4	Gene names	STMN3, SCLIP
Domain Architecture
Description	Stathmin-3 (SCG10-like protein).

STXB4_HUMAN
θ value	0.365318 (rank : 926)	NC score	0.297553 (rank : 573)
Query Neighborhood Hits	1371	Target Neighborhood Hits	616	Shared Neighborhood Hits	394
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TACC1_MOUSE
θ value	0.365318 (rank : 927)	NC score	0.326820 (rank : 506)
Query Neighborhood Hits	1371	Target Neighborhood Hits	667	Shared Neighborhood Hits	428
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TNNI2_MOUSE
θ value	0.365318 (rank : 928)	NC score	0.069471 (rank : 1760)
Query Neighborhood Hits	1371	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	P13412	Gene names	Tnni2
Domain Architecture
Description	Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).

ACINU_MOUSE
θ value	0.47712 (rank : 929)	NC score	0.224337 (rank : 772)
Query Neighborhood Hits	1371	Target Neighborhood Hits	712	Shared Neighborhood Hits	335
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BRAP_HUMAN
θ value	0.47712 (rank : 930)	NC score	0.283660 (rank : 598)
Query Neighborhood Hits	1371	Target Neighborhood Hits	560	Shared Neighborhood Hits	353
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

CABP7_HUMAN
θ value	0.47712 (rank : 931)	NC score	0.047600 (rank : 2187)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	46
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
θ value	0.47712 (rank : 932)	NC score	0.047600 (rank : 2188)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CCD62_HUMAN
θ value	0.47712 (rank : 933)	NC score	0.447646 (rank : 218)
Query Neighborhood Hits	1371	Target Neighborhood Hits	631	Shared Neighborhood Hits	463
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CD2L1_HUMAN
θ value	0.47712 (rank : 934)	NC score	0.105521 (rank : 1421)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1467	Shared Neighborhood Hits	439
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CENPH_MOUSE
θ value	0.47712 (rank : 935)	NC score	0.238924 (rank : 730)
Query Neighborhood Hits	1371	Target Neighborhood Hits	195	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

CNTRB_HUMAN
θ value	0.47712 (rank : 936)	NC score	0.414115 (rank : 319)
Query Neighborhood Hits	1371	Target Neighborhood Hits	690	Shared Neighborhood Hits	469
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

DIAP1_MOUSE
θ value	0.47712 (rank : 937)	NC score	0.228294 (rank : 759)
Query Neighborhood Hits	1371	Target Neighborhood Hits	839	Shared Neighborhood Hits	433
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

EZRI_HUMAN
θ value	0.47712 (rank : 938)	NC score	0.278434 (rank : 615)
Query Neighborhood Hits	1371	Target Neighborhood Hits	663	Shared Neighborhood Hits	491
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FER_HUMAN
θ value	0.47712 (rank : 939)	NC score	0.137392 (rank : 1180)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1278	Shared Neighborhood Hits	432
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

IDLC_MOUSE
θ value	0.47712 (rank : 940)	NC score	0.231962 (rank : 749)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	243
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

K1C10_MOUSE
θ value	0.47712 (rank : 941)	NC score	0.169478 (rank : 986)
Query Neighborhood Hits	1371	Target Neighborhood Hits	466	Shared Neighborhood Hits	335
SwissProt Accessions	P02535, P08731, Q8BUX3, Q8BV09, Q8BVU3, Q9CXH6, Q9JKB4	Gene names	Krt10, Krt1-10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) (56 kDa cytokeratin) (Keratin, type I cytoskeletal 59 kDa).

K1HB_HUMAN
θ value	0.47712 (rank : 942)	NC score	0.180688 (rank : 921)
Query Neighborhood Hits	1371	Target Neighborhood Hits	470	Shared Neighborhood Hits	344
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

LRRF1_HUMAN
θ value	0.47712 (rank : 943)	NC score	0.272643 (rank : 631)
Query Neighborhood Hits	1371	Target Neighborhood Hits	625	Shared Neighborhood Hits	375
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

NARG1_HUMAN
θ value	0.47712 (rank : 944)	NC score	0.058247 (rank : 1919)
Query Neighborhood Hits	1371	Target Neighborhood Hits	114	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

NARG1_MOUSE
θ value	0.47712 (rank : 945)	NC score	0.057829 (rank : 1932)
Query Neighborhood Hits	1371	Target Neighborhood Hits	111	Shared Neighborhood Hits	61
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

NARGL_MOUSE
θ value	0.47712 (rank : 946)	NC score	0.076227 (rank : 1674)
Query Neighborhood Hits	1371	Target Neighborhood Hits	175	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NBR1_MOUSE
θ value	0.47712 (rank : 947)	NC score	0.034505 (rank : 2236)
Query Neighborhood Hits	1371	Target Neighborhood Hits	116	Shared Neighborhood Hits	36
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

SEPT7_MOUSE
θ value	0.47712 (rank : 948)	NC score	0.122407 (rank : 1283)
Query Neighborhood Hits	1371	Target Neighborhood Hits	327	Shared Neighborhood Hits	247
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SH24A_HUMAN
θ value	0.47712 (rank : 949)	NC score	0.226226 (rank : 767)
Query Neighborhood Hits	1371	Target Neighborhood Hits	455	Shared Neighborhood Hits	278
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

SH24A_MOUSE
θ value	0.47712 (rank : 950)	NC score	0.134217 (rank : 1197)
Query Neighborhood Hits	1371	Target Neighborhood Hits	326	Shared Neighborhood Hits	182
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SYT4_HUMAN
θ value	0.47712 (rank : 951)	NC score	0.151924 (rank : 1087)
Query Neighborhood Hits	1371	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

TJAP1_MOUSE
θ value	0.47712 (rank : 952)	NC score	0.181012 (rank : 919)
Query Neighborhood Hits	1371	Target Neighborhood Hits	295	Shared Neighborhood Hits	214
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TNNT1_HUMAN
θ value	0.47712 (rank : 953)	NC score	0.152736 (rank : 1081)
Query Neighborhood Hits	1371	Target Neighborhood Hits	211	Shared Neighborhood Hits	164
SwissProt Accessions	P13805, O95472, Q16061	Gene names	TNNT1, TNT
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

TNNT1_MOUSE
θ value	0.47712 (rank : 954)	NC score	0.173458 (rank : 962)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	185
SwissProt Accessions	O88346, O88795, Q9QUP7	Gene names	Tnnt1
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

TRI62_HUMAN
θ value	0.47712 (rank : 955)	NC score	0.094216 (rank : 1502)
Query Neighborhood Hits	1371	Target Neighborhood Hits	584	Shared Neighborhood Hits	303
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

U2AFM_HUMAN
θ value	0.47712 (rank : 956)	NC score	0.281628 (rank : 604)
Query Neighborhood Hits	1371	Target Neighborhood Hits	577	Shared Neighborhood Hits	417
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

ZN318_HUMAN
θ value	0.47712 (rank : 957)	NC score	0.136025 (rank : 1188)
Query Neighborhood Hits	1371	Target Neighborhood Hits	497	Shared Neighborhood Hits	231
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

AMRP_MOUSE
θ value	0.62314 (rank : 958)	NC score	0.170363 (rank : 981)
Query Neighborhood Hits	1371	Target Neighborhood Hits	173	Shared Neighborhood Hits	146
SwissProt Accessions	P55302	Gene names	Lrpap1
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin-binding protein 44) (HBP-44).

CCD37_HUMAN
θ value	0.62314 (rank : 959)	NC score	0.178990 (rank : 929)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	203
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CCD38_HUMAN
θ value	0.62314 (rank : 960)	NC score	0.203707 (rank : 836)
Query Neighborhood Hits	1371	Target Neighborhood Hits	287	Shared Neighborhood Hits	222
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CENPQ_HUMAN
θ value	0.62314 (rank : 961)	NC score	0.141810 (rank : 1153)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	103
SwissProt Accessions	Q7L2Z9, Q6IN61, Q9NVS5	Gene names	CENPQ, C6orf139
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

GOPC_MOUSE
θ value	0.62314 (rank : 962)	NC score	0.111649 (rank : 1370)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

IDLC_HUMAN
θ value	0.62314 (rank : 963)	NC score	0.247187 (rank : 704)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	264
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

K1C18_HUMAN
θ value	0.62314 (rank : 964)	NC score	0.179909 (rank : 925)
Query Neighborhood Hits	1371	Target Neighborhood Hits	441	Shared Neighborhood Hits	335
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

KNTC2_MOUSE
θ value	0.62314 (rank : 965)	NC score	0.432310 (rank : 262)
Query Neighborhood Hits	1371	Target Neighborhood Hits	692	Shared Neighborhood Hits	479
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

LIN1_HUMAN
θ value	0.62314 (rank : 966)	NC score	0.116767 (rank : 1324)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	127
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

LMNB1_HUMAN
θ value	0.62314 (rank : 967)	NC score	0.321458 (rank : 515)
Query Neighborhood Hits	1371	Target Neighborhood Hits	714	Shared Neighborhood Hits	506
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

MPP8_HUMAN
θ value	0.62314 (rank : 968)	NC score	0.152533 (rank : 1084)
Query Neighborhood Hits	1371	Target Neighborhood Hits	948	Shared Neighborhood Hits	330
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYO5A_MOUSE
θ value	0.62314 (rank : 969)	NC score	0.354418 (rank : 459)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1117	Shared Neighborhood Hits	661
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

NARGL_HUMAN
θ value	0.62314 (rank : 970)	NC score	0.100127 (rank : 1463)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	148
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NDE1_HUMAN
θ value	0.62314 (rank : 971)	NC score	0.394999 (rank : 371)
Query Neighborhood Hits	1371	Target Neighborhood Hits	823	Shared Neighborhood Hits	551
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

SEPT6_MOUSE
θ value	0.62314 (rank : 972)	NC score	0.077285 (rank : 1663)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	185
SwissProt Accessions	Q9R1T4, Q91XH2, Q9CZ94	Gene names	Sept6
Domain Architecture
Description	Septin-6.

SLAP2_MOUSE
θ value	0.62314 (rank : 973)	NC score	0.185254 (rank : 899)
Query Neighborhood Hits	1371	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SPC25_HUMAN
θ value	0.62314 (rank : 974)	NC score	0.224024 (rank : 773)
Query Neighborhood Hits	1371	Target Neighborhood Hits	273	Shared Neighborhood Hits	217
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

TXLNG_MOUSE
θ value	0.62314 (rank : 975)	NC score	0.360145 (rank : 444)
Query Neighborhood Hits	1371	Target Neighborhood Hits	552	Shared Neighborhood Hits	415
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

CCDC5_HUMAN
θ value	0.813845 (rank : 976)	NC score	0.135197 (rank : 1190)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	114
SwissProt Accessions	Q96CS2, Q8N837	Gene names	CCDC5, HEIC
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5 (Enhancer of invasion-cluster) (HEI-C).

CD209_HUMAN
θ value	0.813845 (rank : 977)	NC score	0.056086 (rank : 1964)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NNX6, Q96QP7, Q96QP8, Q96QP9, Q96QQ0, Q96QQ1, Q96QQ2, Q96QQ3, Q96QQ4, Q96QQ5, Q96QQ6, Q96QQ7, Q96QQ8	Gene names	CD209, CLEC4L
Domain Architecture
Description	CD209 antigen (Dendritic cell-specific ICAM-3-grabbing nonintegrin 1) (DC-SIGN1) (DC-SIGN) (C-type lectin domain family 4 member L).

CD2L1_MOUSE
θ value	0.813845 (rank : 978)	NC score	0.108102 (rank : 1395)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1463	Shared Neighborhood Hits	441
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

DOCK2_MOUSE
θ value	0.813845 (rank : 979)	NC score	0.051431 (rank : 2125)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

HM20A_MOUSE
θ value	0.813845 (rank : 980)	NC score	0.131473 (rank : 1226)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	202
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

K0831_HUMAN
θ value	0.813845 (rank : 981)	NC score	0.158321 (rank : 1050)
Query Neighborhood Hits	1371	Target Neighborhood Hits	203	Shared Neighborhood Hits	164
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

K2C1_MOUSE
θ value	0.813845 (rank : 982)	NC score	0.164590 (rank : 1014)
Query Neighborhood Hits	1371	Target Neighborhood Hits	477	Shared Neighborhood Hits	351
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

LIPB2_HUMAN
θ value	0.813845 (rank : 983)	NC score	0.317088 (rank : 531)
Query Neighborhood Hits	1371	Target Neighborhood Hits	599	Shared Neighborhood Hits	422
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

MIA2_MOUSE
θ value	0.813845 (rank : 984)	NC score	0.039270 (rank : 2218)
Query Neighborhood Hits	1371	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

MPP4_MOUSE
θ value	0.813845 (rank : 985)	NC score	0.103707 (rank : 1431)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MYO5A_HUMAN
θ value	0.813845 (rank : 986)	NC score	0.357364 (rank : 452)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1092	Shared Neighborhood Hits	647
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NCOR2_HUMAN
θ value	0.813845 (rank : 987)	NC score	0.122266 (rank : 1284)
Query Neighborhood Hits	1371	Target Neighborhood Hits	870	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NUCB1_MOUSE
θ value	0.813845 (rank : 988)	NC score	0.234491 (rank : 741)
Query Neighborhood Hits	1371	Target Neighborhood Hits	414	Shared Neighborhood Hits	293
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUCB2_HUMAN
θ value	0.813845 (rank : 989)	NC score	0.229478 (rank : 756)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	232
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

ONCO_HUMAN
θ value	0.813845 (rank : 990)	NC score	0.058296 (rank : 1916)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

PA24A_HUMAN
θ value	0.813845 (rank : 991)	NC score	0.098886 (rank : 1469)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

RENT2_HUMAN
θ value	0.813845 (rank : 992)	NC score	0.315846 (rank : 534)
Query Neighborhood Hits	1371	Target Neighborhood Hits	618	Shared Neighborhood Hits	396
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RIMS2_HUMAN
θ value	0.813845 (rank : 993)	NC score	0.128937 (rank : 1242)
Query Neighborhood Hits	1371	Target Neighborhood Hits	342	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.813845 (rank : 994)	NC score	0.128799 (rank : 1245)
Query Neighborhood Hits	1371	Target Neighborhood Hits	376	Shared Neighborhood Hits	149
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SEPT6_HUMAN
θ value	0.813845 (rank : 995)	NC score	0.068656 (rank : 1767)
Query Neighborhood Hits	1371	Target Neighborhood Hits	220	Shared Neighborhood Hits	160
SwissProt Accessions	Q14141, Q5JTK0, Q969W5, Q96A13, Q96GR1, Q96P86, Q96P87	Gene names	SEPT6, KIAA0128, SEP2
Domain Architecture
Description	Septin-6.

SIN3B_HUMAN
θ value	0.813845 (rank : 996)	NC score	0.019464 (rank : 2288)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	30
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

SIN3B_MOUSE
θ value	0.813845 (rank : 997)	NC score	0.021419 (rank : 2282)
Query Neighborhood Hits	1371	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	Q62141, O54976, Q6A013, Q8VCB8, Q8VDZ5	Gene names	Sin3b, Kiaa0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

TACC3_MOUSE
θ value	0.813845 (rank : 998)	NC score	0.329197 (rank : 503)
Query Neighborhood Hits	1371	Target Neighborhood Hits	607	Shared Neighborhood Hits	426
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TMC2_MOUSE
θ value	0.813845 (rank : 999)	NC score	0.045557 (rank : 2198)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	100
SwissProt Accessions	Q8R4P4	Gene names	Tmc2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

TTC1_HUMAN
θ value	0.813845 (rank : 1000)	NC score	0.089281 (rank : 1548)
Query Neighborhood Hits	1371	Target Neighborhood Hits	417	Shared Neighborhood Hits	184
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TXLNG_HUMAN
θ value	0.813845 (rank : 1001)	NC score	0.360090 (rank : 445)
Query Neighborhood Hits	1371	Target Neighborhood Hits	568	Shared Neighborhood Hits	426
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

ACINU_HUMAN
θ value	1.06291 (rank : 1002)	NC score	0.206041 (rank : 829)
Query Neighborhood Hits	1371	Target Neighborhood Hits	828	Shared Neighborhood Hits	352
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ANR35_HUMAN
θ value	1.06291 (rank : 1003)	NC score	0.189257 (rank : 881)
Query Neighborhood Hits	1371	Target Neighborhood Hits	784	Shared Neighborhood Hits	377
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

CEP70_MOUSE
θ value	1.06291 (rank : 1004)	NC score	0.361739 (rank : 440)
Query Neighborhood Hits	1371	Target Neighborhood Hits	532	Shared Neighborhood Hits	408
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CF152_MOUSE
θ value	1.06291 (rank : 1005)	NC score	0.351535 (rank : 465)
Query Neighborhood Hits	1371	Target Neighborhood Hits	597	Shared Neighborhood Hits	419
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CPSF2_HUMAN
θ value	1.06291 (rank : 1006)	NC score	0.024659 (rank : 2267)
Query Neighborhood Hits	1371	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

CPSF2_MOUSE
θ value	1.06291 (rank : 1007)	NC score	0.024838 (rank : 2266)
Query Neighborhood Hits	1371	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	O35218	Gene names	Cpsf2, Cpsf100, Mcpsf
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

CSKI2_HUMAN
θ value	1.06291 (rank : 1008)	NC score	0.040045 (rank : 2216)
Query Neighborhood Hits	1371	Target Neighborhood Hits	747	Shared Neighborhood Hits	105
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	1.06291 (rank : 1009)	NC score	0.045122 (rank : 2201)
Query Neighborhood Hits	1371	Target Neighborhood Hits	812	Shared Neighborhood Hits	120
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DLG2_HUMAN
θ value	1.06291 (rank : 1010)	NC score	0.082656 (rank : 1614)
Query Neighborhood Hits	1371	Target Neighborhood Hits	279	Shared Neighborhood Hits	105
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DMP1_HUMAN
θ value	1.06291 (rank : 1011)	NC score	0.058740 (rank : 1904)
Query Neighborhood Hits	1371	Target Neighborhood Hits	491	Shared Neighborhood Hits	118
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DZIP1_MOUSE
θ value	1.06291 (rank : 1012)	NC score	0.240620 (rank : 726)
Query Neighborhood Hits	1371	Target Neighborhood Hits	530	Shared Neighborhood Hits	236
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

ES8L1_HUMAN
θ value	1.06291 (rank : 1013)	NC score	0.159915 (rank : 1039)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	113
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

HAP1_HUMAN
θ value	1.06291 (rank : 1014)	NC score	0.355472 (rank : 455)
Query Neighborhood Hits	1371	Target Neighborhood Hits	606	Shared Neighborhood Hits	439
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HM20A_HUMAN
θ value	1.06291 (rank : 1015)	NC score	0.128928 (rank : 1243)
Query Neighborhood Hits	1371	Target Neighborhood Hits	343	Shared Neighborhood Hits	201
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

K1C20_HUMAN
θ value	1.06291 (rank : 1016)	NC score	0.177542 (rank : 936)
Query Neighborhood Hits	1371	Target Neighborhood Hits	468	Shared Neighborhood Hits	354
SwissProt Accessions	P35900	Gene names	KRT20
Domain Architecture
Description	Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT).

K22E_HUMAN
θ value	1.06291 (rank : 1017)	NC score	0.180935 (rank : 920)
Query Neighborhood Hits	1371	Target Neighborhood Hits	515	Shared Neighborhood Hits	356
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

LAMB1_HUMAN
θ value	1.06291 (rank : 1018)	NC score	0.193816 (rank : 869)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1018	Shared Neighborhood Hits	430
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MED4_HUMAN
θ value	1.06291 (rank : 1019)	NC score	0.085644 (rank : 1581)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NPJ6, Q5T912, Q6FHC4, Q6IA79, Q9BS95, Q9NYR5	Gene names	MED4, ARC36, DRIP36, VDRIP
Domain Architecture	No domain graphic available
Description	Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36) (Activator-recruited cofactor 36 kDa component) (ARC36) (TRAP/SMCC/PC2 subunit p36 subunit).

MERL_MOUSE
θ value	1.06291 (rank : 1020)	NC score	0.233036 (rank : 745)
Query Neighborhood Hits	1371	Target Neighborhood Hits	524	Shared Neighborhood Hits	392
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

NCOR2_MOUSE
θ value	1.06291 (rank : 1021)	NC score	0.131742 (rank : 1224)
Query Neighborhood Hits	1371	Target Neighborhood Hits	790	Shared Neighborhood Hits	274
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NFH_MOUSE
θ value	1.06291 (rank : 1022)	NC score	0.153250 (rank : 1079)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2247	Shared Neighborhood Hits	544
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PA24B_HUMAN
θ value	1.06291 (rank : 1023)	NC score	0.101372 (rank : 1450)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PAWR_HUMAN
θ value	1.06291 (rank : 1024)	NC score	0.187553 (rank : 886)
Query Neighborhood Hits	1371	Target Neighborhood Hits	252	Shared Neighborhood Hits	160
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

PER2_MOUSE
θ value	1.06291 (rank : 1025)	NC score	0.012578 (rank : 2307)
Query Neighborhood Hits	1371	Target Neighborhood Hits	325	Shared Neighborhood Hits	50
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PLCB3_HUMAN
θ value	1.06291 (rank : 1026)	NC score	0.196102 (rank : 858)
Query Neighborhood Hits	1371	Target Neighborhood Hits	445	Shared Neighborhood Hits	310
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PPIP2_HUMAN
θ value	1.06291 (rank : 1027)	NC score	0.222499 (rank : 777)
Query Neighborhood Hits	1371	Target Neighborhood Hits	254	Shared Neighborhood Hits	212
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

RCOR2_HUMAN
θ value	1.06291 (rank : 1028)	NC score	0.008606 (rank : 2319)
Query Neighborhood Hits	1371	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

SASH1_MOUSE
θ value	1.06291 (rank : 1029)	NC score	0.080605 (rank : 1627)
Query Neighborhood Hits	1371	Target Neighborhood Hits	263	Shared Neighborhood Hits	87
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SEP10_MOUSE
θ value	1.06291 (rank : 1030)	NC score	0.041419 (rank : 2212)
Query Neighborhood Hits	1371	Target Neighborhood Hits	145	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

SHLB1_HUMAN
θ value	1.06291 (rank : 1031)	NC score	0.162917 (rank : 1022)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SLY_MOUSE
θ value	1.06291 (rank : 1032)	NC score	0.118886 (rank : 1311)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SMOC1_HUMAN
θ value	1.06291 (rank : 1033)	NC score	0.015952 (rank : 2296)
Query Neighborhood Hits	1371	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

STAG3_HUMAN
θ value	1.06291 (rank : 1034)	NC score	0.010158 (rank : 2316)
Query Neighborhood Hits	1371	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

SYTL1_MOUSE
θ value	1.06291 (rank : 1035)	NC score	0.123764 (rank : 1276)
Query Neighborhood Hits	1371	Target Neighborhood Hits	314	Shared Neighborhood Hits	101
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TAOK2_HUMAN
θ value	1.06291 (rank : 1036)	NC score	0.106103 (rank : 1417)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1172	Shared Neighborhood Hits	336
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

TRI68_MOUSE
θ value	1.06291 (rank : 1037)	NC score	0.028564 (rank : 2257)
Query Neighborhood Hits	1371	Target Neighborhood Hits	356	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

UBXD2_MOUSE
θ value	1.06291 (rank : 1038)	NC score	0.114410 (rank : 1351)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	134
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

ADA30_HUMAN
θ value	1.38821 (rank : 1039)	NC score	0.002791 (rank : 2334)
Query Neighborhood Hits	1371	Target Neighborhood Hits	391	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ANGL2_HUMAN
θ value	1.38821 (rank : 1040)	NC score	0.021936 (rank : 2280)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_MOUSE
θ value	1.38821 (rank : 1041)	NC score	0.022975 (rank : 2274)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

BRDT_MOUSE
θ value	1.38821 (rank : 1042)	NC score	0.044471 (rank : 2205)
Query Neighborhood Hits	1371	Target Neighborhood Hits	243	Shared Neighborhood Hits	107
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CA026_MOUSE
θ value	1.38821 (rank : 1043)	NC score	0.035285 (rank : 2230)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

CEP57_HUMAN
θ value	1.38821 (rank : 1044)	NC score	0.381548 (rank : 401)
Query Neighborhood Hits	1371	Target Neighborhood Hits	576	Shared Neighborhood Hits	437
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

CETN3_HUMAN
θ value	1.38821 (rank : 1045)	NC score	0.034248 (rank : 2238)
Query Neighborhood Hits	1371	Target Neighborhood Hits	211	Shared Neighborhood Hits	48
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
θ value	1.38821 (rank : 1046)	NC score	0.034564 (rank : 2233)
Query Neighborhood Hits	1371	Target Neighborhood Hits	208	Shared Neighborhood Hits	47
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

CF152_HUMAN
θ value	1.38821 (rank : 1047)	NC score	0.399272 (rank : 360)
Query Neighborhood Hits	1371	Target Neighborhood Hits	704	Shared Neighborhood Hits	484
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CHD9_HUMAN
θ value	1.38821 (rank : 1048)	NC score	0.014486 (rank : 2302)
Query Neighborhood Hits	1371	Target Neighborhood Hits	343	Shared Neighborhood Hits	88
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

DIAP3_MOUSE
θ value	1.38821 (rank : 1049)	NC score	0.060741 (rank : 1868)
Query Neighborhood Hits	1371	Target Neighborhood Hits	221	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DLG2_MOUSE
θ value	1.38821 (rank : 1050)	NC score	0.082846 (rank : 1611)
Query Neighborhood Hits	1371	Target Neighborhood Hits	271	Shared Neighborhood Hits	105
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

GCP6_HUMAN
θ value	1.38821 (rank : 1051)	NC score	0.137390 (rank : 1181)
Query Neighborhood Hits	1371	Target Neighborhood Hits	295	Shared Neighborhood Hits	178
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

GOPC_HUMAN
θ value	1.38821 (rank : 1052)	NC score	0.131977 (rank : 1220)
Query Neighborhood Hits	1371	Target Neighborhood Hits	377	Shared Neighborhood Hits	198
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GPR98_MOUSE
θ value	1.38821 (rank : 1053)	NC score	-0.000095 (rank : 2342)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

K2C5_MOUSE
θ value	1.38821 (rank : 1054)	NC score	0.173434 (rank : 963)
Query Neighborhood Hits	1371	Target Neighborhood Hits	505	Shared Neighborhood Hits	375
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

LAMB1_MOUSE
θ value	1.38821 (rank : 1055)	NC score	0.154117 (rank : 1077)
Query Neighborhood Hits	1371	Target Neighborhood Hits	919	Shared Neighborhood Hits	383
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRC47_MOUSE
θ value	1.38821 (rank : 1056)	NC score	-0.004190 (rank : 2346)
Query Neighborhood Hits	1371	Target Neighborhood Hits	299	Shared Neighborhood Hits	11
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

MAP1B_HUMAN
θ value	1.38821 (rank : 1057)	NC score	0.174524 (rank : 956)
Query Neighborhood Hits	1371	Target Neighborhood Hits	903	Shared Neighborhood Hits	308
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MERL_HUMAN
θ value	1.38821 (rank : 1058)	NC score	0.232474 (rank : 747)
Query Neighborhood Hits	1371	Target Neighborhood Hits	532	Shared Neighborhood Hits	392
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MNT_HUMAN
θ value	1.38821 (rank : 1059)	NC score	0.062558 (rank : 1844)
Query Neighborhood Hits	1371	Target Neighborhood Hits	496	Shared Neighborhood Hits	116
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

OBSCN_HUMAN
θ value	1.38821 (rank : 1060)	NC score	0.078877 (rank : 1650)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1931	Shared Neighborhood Hits	203
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ONCO_MOUSE
θ value	1.38821 (rank : 1061)	NC score	0.058269 (rank : 1918)
Query Neighborhood Hits	1371	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	P51879, Q62004	Gene names	Ocm
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

PA24E_MOUSE
θ value	1.38821 (rank : 1062)	NC score	0.104710 (rank : 1427)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PICAL_HUMAN
θ value	1.38821 (rank : 1063)	NC score	0.019984 (rank : 2287)
Query Neighborhood Hits	1371	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

PICA_MOUSE
θ value	1.38821 (rank : 1064)	NC score	0.022994 (rank : 2273)
Query Neighborhood Hits	1371	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

RFC1_HUMAN
θ value	1.38821 (rank : 1065)	NC score	0.054709 (rank : 1992)
Query Neighborhood Hits	1371	Target Neighborhood Hits	352	Shared Neighborhood Hits	118
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RPGR1_MOUSE
θ value	1.38821 (rank : 1066)	NC score	0.294433 (rank : 577)
Query Neighborhood Hits	1371	Target Neighborhood Hits	713	Shared Neighborhood Hits	418
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SHLB1_MOUSE
θ value	1.38821 (rank : 1067)	NC score	0.160339 (rank : 1035)
Query Neighborhood Hits	1371	Target Neighborhood Hits	101	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SPC25_MOUSE
θ value	1.38821 (rank : 1068)	NC score	0.197399 (rank : 850)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	206
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

SRMS_MOUSE
θ value	1.38821 (rank : 1069)	NC score	0.093576 (rank : 1509)
Query Neighborhood Hits	1371	Target Neighborhood Hits	964	Shared Neighborhood Hits	173
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

STIM2_MOUSE
θ value	1.38821 (rank : 1070)	NC score	0.217084 (rank : 798)
Query Neighborhood Hits	1371	Target Neighborhood Hits	403	Shared Neighborhood Hits	313
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

TLK2_MOUSE
θ value	1.38821 (rank : 1071)	NC score	0.093014 (rank : 1513)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1088	Shared Neighborhood Hits	325
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

TR150_HUMAN
θ value	1.38821 (rank : 1072)	NC score	0.035425 (rank : 2229)
Query Neighborhood Hits	1371	Target Neighborhood Hits	313	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TTC14_HUMAN
θ value	1.38821 (rank : 1073)	NC score	0.152540 (rank : 1083)
Query Neighborhood Hits	1371	Target Neighborhood Hits	274	Shared Neighborhood Hits	142
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

U2AFL_HUMAN
θ value	1.38821 (rank : 1074)	NC score	0.253624 (rank : 684)
Query Neighborhood Hits	1371	Target Neighborhood Hits	503	Shared Neighborhood Hits	368
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

U2AFL_MOUSE
θ value	1.38821 (rank : 1075)	NC score	0.199005 (rank : 845)
Query Neighborhood Hits	1371	Target Neighborhood Hits	389	Shared Neighborhood Hits	286
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

ZC313_HUMAN
θ value	1.38821 (rank : 1076)	NC score	0.305811 (rank : 548)
Query Neighborhood Hits	1371	Target Neighborhood Hits	772	Shared Neighborhood Hits	368
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

AMOT_HUMAN
θ value	1.81305 (rank : 1077)	NC score	0.298422 (rank : 567)
Query Neighborhood Hits	1371	Target Neighborhood Hits	712	Shared Neighborhood Hits	391
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ANR11_HUMAN
θ value	1.81305 (rank : 1078)	NC score	0.142158 (rank : 1149)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1289	Shared Neighborhood Hits	400
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CABP2_HUMAN
θ value	1.81305 (rank : 1079)	NC score	0.031438 (rank : 2244)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CAC1B_HUMAN
θ value	1.81305 (rank : 1080)	NC score	0.003273 (rank : 2332)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	38
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CENPH_HUMAN
θ value	1.81305 (rank : 1081)	NC score	0.316204 (rank : 533)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

CEP57_MOUSE
θ value	1.81305 (rank : 1082)	NC score	0.379500 (rank : 406)
Query Neighborhood Hits	1371	Target Neighborhood Hits	580	Shared Neighborhood Hits	440
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CM007_HUMAN
θ value	1.81305 (rank : 1083)	NC score	0.186432 (rank : 895)
Query Neighborhood Hits	1371	Target Neighborhood Hits	422	Shared Neighborhood Hits	221
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CN094_MOUSE
θ value	1.81305 (rank : 1084)	NC score	0.035437 (rank : 2228)
Query Neighborhood Hits	1371	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BFT2, Q99KI1	Gene names	D14Ertd500e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf94 homolog.

DLG1_HUMAN
θ value	1.81305 (rank : 1085)	NC score	0.075847 (rank : 1679)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	108
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG3_HUMAN
θ value	1.81305 (rank : 1086)	NC score	0.079545 (rank : 1642)
Query Neighborhood Hits	1371	Target Neighborhood Hits	269	Shared Neighborhood Hits	105
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	1.81305 (rank : 1087)	NC score	0.079397 (rank : 1644)
Query Neighborhood Hits	1371	Target Neighborhood Hits	274	Shared Neighborhood Hits	105
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

EPS8_HUMAN
θ value	1.81305 (rank : 1088)	NC score	0.152344 (rank : 1086)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	116
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
θ value	1.81305 (rank : 1089)	NC score	0.158425 (rank : 1048)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	136
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EXOC5_MOUSE
θ value	1.81305 (rank : 1090)	NC score	0.131686 (rank : 1225)
Query Neighborhood Hits	1371	Target Neighborhood Hits	194	Shared Neighborhood Hits	152
SwissProt Accessions	Q3TPX4	Gene names	Exoc5, Sec10l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 5 (Exocyst complex component Sec10).

G45IP_HUMAN
θ value	1.81305 (rank : 1091)	NC score	0.132358 (rank : 1215)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

INOC1_HUMAN
θ value	1.81305 (rank : 1092)	NC score	0.034640 (rank : 2232)
Query Neighborhood Hits	1371	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	1.81305 (rank : 1093)	NC score	0.032097 (rank : 2243)
Query Neighborhood Hits	1371	Target Neighborhood Hits	178	Shared Neighborhood Hits	96
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

KI13A_MOUSE
θ value	1.81305 (rank : 1094)	NC score	0.134181 (rank : 1198)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	260
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

LAMA1_MOUSE
θ value	1.81305 (rank : 1095)	NC score	0.102382 (rank : 1441)
Query Neighborhood Hits	1371	Target Neighborhood Hits	838	Shared Neighborhood Hits	280
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC1_MOUSE
θ value	1.81305 (rank : 1096)	NC score	0.154756 (rank : 1073)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	343
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LIPA3_HUMAN
θ value	1.81305 (rank : 1097)	NC score	0.382459 (rank : 399)
Query Neighborhood Hits	1371	Target Neighborhood Hits	828	Shared Neighborhood Hits	537
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPA3_MOUSE
θ value	1.81305 (rank : 1098)	NC score	0.317272 (rank : 530)
Query Neighborhood Hits	1371	Target Neighborhood Hits	636	Shared Neighborhood Hits	437
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LRC27_HUMAN
θ value	1.81305 (rank : 1099)	NC score	0.158087 (rank : 1052)
Query Neighborhood Hits	1371	Target Neighborhood Hits	710	Shared Neighborhood Hits	305
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

MEOX1_MOUSE
θ value	1.81305 (rank : 1100)	NC score	-0.007476 (rank : 2351)
Query Neighborhood Hits	1371	Target Neighborhood Hits	345	Shared Neighborhood Hits	12
SwissProt Accessions	P32442	Gene names	Meox1, Mox-1, Mox1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

MNT_MOUSE
θ value	1.81305 (rank : 1101)	NC score	0.067941 (rank : 1779)
Query Neighborhood Hits	1371	Target Neighborhood Hits	432	Shared Neighborhood Hits	108
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYO15_HUMAN
θ value	1.81305 (rank : 1102)	NC score	0.126640 (rank : 1261)
Query Neighborhood Hits	1371	Target Neighborhood Hits	671	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NFL_HUMAN
θ value	1.81305 (rank : 1103)	NC score	0.204114 (rank : 833)
Query Neighborhood Hits	1371	Target Neighborhood Hits	666	Shared Neighborhood Hits	426
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NIPBL_HUMAN
θ value	1.81305 (rank : 1104)	NC score	0.107506 (rank : 1403)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1311	Shared Neighborhood Hits	337
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

OPHN1_HUMAN
θ value	1.81305 (rank : 1105)	NC score	0.061093 (rank : 1864)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	75
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

PLCB1_HUMAN
θ value	1.81305 (rank : 1106)	NC score	0.260406 (rank : 657)
Query Neighborhood Hits	1371	Target Neighborhood Hits	614	Shared Neighborhood Hits	411
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB1_MOUSE
θ value	1.81305 (rank : 1107)	NC score	0.245261 (rank : 711)
Query Neighborhood Hits	1371	Target Neighborhood Hits	531	Shared Neighborhood Hits	376
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

RHG09_HUMAN
θ value	1.81305 (rank : 1108)	NC score	0.075395 (rank : 1685)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SLY_HUMAN
θ value	1.81305 (rank : 1109)	NC score	0.101921 (rank : 1446)
Query Neighborhood Hits	1371	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SPAG5_MOUSE
θ value	1.81305 (rank : 1110)	NC score	0.400882 (rank : 355)
Query Neighborhood Hits	1371	Target Neighborhood Hits	612	Shared Neighborhood Hits	432
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SPG16_HUMAN
θ value	1.81305 (rank : 1111)	NC score	0.012843 (rank : 2306)
Query Neighborhood Hits	1371	Target Neighborhood Hits	361	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

SYT11_HUMAN
θ value	1.81305 (rank : 1112)	NC score	0.146892 (rank : 1118)
Query Neighborhood Hits	1371	Target Neighborhood Hits	113	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
θ value	1.81305 (rank : 1113)	NC score	0.146905 (rank : 1117)
Query Neighborhood Hits	1371	Target Neighborhood Hits	116	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

TCOF_HUMAN
θ value	1.81305 (rank : 1114)	NC score	0.047082 (rank : 2189)
Query Neighborhood Hits	1371	Target Neighborhood Hits	543	Shared Neighborhood Hits	104
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TR150_MOUSE
θ value	1.81305 (rank : 1115)	NC score	0.062689 (rank : 1842)
Query Neighborhood Hits	1371	Target Neighborhood Hits	468	Shared Neighborhood Hits	147
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRDN_HUMAN
θ value	1.81305 (rank : 1116)	NC score	0.242776 (rank : 719)
Query Neighborhood Hits	1371	Target Neighborhood Hits	542	Shared Neighborhood Hits	256
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRIM6_HUMAN
θ value	1.81305 (rank : 1117)	NC score	0.045742 (rank : 2197)
Query Neighborhood Hits	1371	Target Neighborhood Hits	412	Shared Neighborhood Hits	163
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

ACADL_MOUSE
θ value	2.36792 (rank : 1118)	NC score	0.000848 (rank : 2339)
Query Neighborhood Hits	1371	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P51174, O35302, Q8QZR6, Q9CU29, Q9DB83	Gene names	Acadl
Domain Architecture
Description	Long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.13) (LCAD).

APLP2_HUMAN
θ value	2.36792 (rank : 1119)	NC score	0.060139 (rank : 1883)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	109
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

APOA1_HUMAN
θ value	2.36792 (rank : 1120)	NC score	0.167993 (rank : 994)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	201
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

BBX_HUMAN
θ value	2.36792 (rank : 1121)	NC score	0.020292 (rank : 2286)
Query Neighborhood Hits	1371	Target Neighborhood Hits	167	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BRE1B_MOUSE
θ value	2.36792 (rank : 1122)	NC score	0.420159 (rank : 298)
Query Neighborhood Hits	1371	Target Neighborhood Hits	970	Shared Neighborhood Hits	566
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

C8AP2_HUMAN
θ value	2.36792 (rank : 1123)	NC score	0.113589 (rank : 1360)
Query Neighborhood Hits	1371	Target Neighborhood Hits	548	Shared Neighborhood Hits	231
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CABP2_MOUSE
θ value	2.36792 (rank : 1124)	NC score	0.030196 (rank : 2253)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP5_MOUSE
θ value	2.36792 (rank : 1125)	NC score	0.031131 (rank : 2245)
Query Neighborhood Hits	1371	Target Neighborhood Hits	207	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CDR2_HUMAN
θ value	2.36792 (rank : 1126)	NC score	0.318170 (rank : 524)
Query Neighborhood Hits	1371	Target Neighborhood Hits	404	Shared Neighborhood Hits	316
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

CN044_MOUSE
θ value	2.36792 (rank : 1127)	NC score	0.033054 (rank : 2239)
Query Neighborhood Hits	1371	Target Neighborhood Hits	57	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CB59, Q8BQX8, Q8BSL9, Q8CBZ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44 homolog.

CPNE3_HUMAN
θ value	2.36792 (rank : 1128)	NC score	0.056788 (rank : 1950)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	62
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CR034_HUMAN
θ value	2.36792 (rank : 1129)	NC score	0.396143 (rank : 368)
Query Neighborhood Hits	1371	Target Neighborhood Hits	538	Shared Neighborhood Hits	405
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CYTSA_HUMAN
θ value	2.36792 (rank : 1130)	NC score	0.436395 (rank : 246)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1138	Shared Neighborhood Hits	639
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	2.36792 (rank : 1131)	NC score	0.441519 (rank : 234)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1104	Shared Neighborhood Hits	636
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DDX20_HUMAN
θ value	2.36792 (rank : 1132)	NC score	-0.002602 (rank : 2345)
Query Neighborhood Hits	1371	Target Neighborhood Hits	121	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DLG1_MOUSE
θ value	2.36792 (rank : 1133)	NC score	0.072597 (rank : 1722)
Query Neighborhood Hits	1371	Target Neighborhood Hits	285	Shared Neighborhood Hits	102
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

ECM2_HUMAN
θ value	2.36792 (rank : 1134)	NC score	-0.009605 (rank : 2353)
Query Neighborhood Hits	1371	Target Neighborhood Hits	402	Shared Neighborhood Hits	28
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

EPIPL_MOUSE
θ value	2.36792 (rank : 1135)	NC score	0.057396 (rank : 1939)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R0W0	Gene names	Eppk1
Domain Architecture
Description	Epiplakin.

EXOC5_HUMAN
θ value	2.36792 (rank : 1136)	NC score	0.131861 (rank : 1221)
Query Neighborhood Hits	1371	Target Neighborhood Hits	194	Shared Neighborhood Hits	153
SwissProt Accessions	O00471	Gene names	EXOC5, SEC10, SEC10L1
Domain Architecture
Description	Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10).

FOXP2_MOUSE
θ value	2.36792 (rank : 1137)	NC score	0.107230 (rank : 1405)
Query Neighborhood Hits	1371	Target Neighborhood Hits	366	Shared Neighborhood Hits	216
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

HDAC4_HUMAN
θ value	2.36792 (rank : 1138)	NC score	0.100000 (rank : 1464)
Query Neighborhood Hits	1371	Target Neighborhood Hits	390	Shared Neighborhood Hits	247
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

HHEX_MOUSE
θ value	2.36792 (rank : 1139)	NC score	-0.005278 (rank : 2347)
Query Neighborhood Hits	1371	Target Neighborhood Hits	350	Shared Neighborhood Hits	17
SwissProt Accessions	P43120	Gene names	Hhex, Prhx
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

IKKB_MOUSE
θ value	2.36792 (rank : 1140)	NC score	0.067492 (rank : 1789)
Query Neighborhood Hits	1371	Target Neighborhood Hits	984	Shared Neighborhood Hits	220
SwissProt Accessions	O88351, Q9R1J6	Gene names	Ikbkb, Ikkb
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

JADE3_MOUSE
θ value	2.36792 (rank : 1141)	NC score	0.011360 (rank : 2312)
Query Neighborhood Hits	1371	Target Neighborhood Hits	174	Shared Neighborhood Hits	43
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

K2C4_HUMAN
θ value	2.36792 (rank : 1142)	NC score	0.173063 (rank : 966)
Query Neighborhood Hits	1371	Target Neighborhood Hits	471	Shared Neighborhood Hits	344
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

KI13B_HUMAN
θ value	2.36792 (rank : 1143)	NC score	0.139909 (rank : 1162)
Query Neighborhood Hits	1371	Target Neighborhood Hits	492	Shared Neighborhood Hits	291
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

LMNA_HUMAN
θ value	2.36792 (rank : 1144)	NC score	0.305296 (rank : 549)
Query Neighborhood Hits	1371	Target Neighborhood Hits	653	Shared Neighborhood Hits	489
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LMNA_MOUSE
θ value	2.36792 (rank : 1145)	NC score	0.309382 (rank : 542)
Query Neighborhood Hits	1371	Target Neighborhood Hits	661	Shared Neighborhood Hits	490
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

LRC45_HUMAN
θ value	2.36792 (rank : 1146)	NC score	0.463063 (rank : 179)
Query Neighborhood Hits	1371	Target Neighborhood Hits	933	Shared Neighborhood Hits	587
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MAP1B_MOUSE
θ value	2.36792 (rank : 1147)	NC score	0.218946 (rank : 790)
Query Neighborhood Hits	1371	Target Neighborhood Hits	977	Shared Neighborhood Hits	363
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MEOX1_HUMAN
θ value	2.36792 (rank : 1148)	NC score	-0.006160 (rank : 2349)
Query Neighborhood Hits	1371	Target Neighborhood Hits	342	Shared Neighborhood Hits	15
SwissProt Accessions	P50221	Gene names	MEOX1, MOX1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

NUCB1_HUMAN
θ value	2.36792 (rank : 1149)	NC score	0.191830 (rank : 874)
Query Neighborhood Hits	1371	Target Neighborhood Hits	359	Shared Neighborhood Hits	252
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUP88_MOUSE
θ value	2.36792 (rank : 1150)	NC score	0.177351 (rank : 938)
Query Neighborhood Hits	1371	Target Neighborhood Hits	239	Shared Neighborhood Hits	198
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

P52K_HUMAN
θ value	2.36792 (rank : 1151)	NC score	0.022852 (rank : 2275)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	52
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

PRP4B_HUMAN
θ value	2.36792 (rank : 1152)	NC score	0.063219 (rank : 1832)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1030	Shared Neighborhood Hits	204
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RBM6_HUMAN
θ value	2.36792 (rank : 1153)	NC score	0.030370 (rank : 2252)
Query Neighborhood Hits	1371	Target Neighborhood Hits	221	Shared Neighborhood Hits	48
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

RGAP1_MOUSE
θ value	2.36792 (rank : 1154)	NC score	0.072235 (rank : 1727)
Query Neighborhood Hits	1371	Target Neighborhood Hits	185	Shared Neighborhood Hits	88
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

SAFB2_HUMAN
θ value	2.36792 (rank : 1155)	NC score	0.271752 (rank : 634)
Query Neighborhood Hits	1371	Target Neighborhood Hits	720	Shared Neighborhood Hits	389
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SEC63_HUMAN
θ value	2.36792 (rank : 1156)	NC score	0.045044 (rank : 2202)
Query Neighborhood Hits	1371	Target Neighborhood Hits	586	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEMG1_HUMAN
θ value	2.36792 (rank : 1157)	NC score	0.057555 (rank : 1938)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	71
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SFPQ_HUMAN
θ value	2.36792 (rank : 1158)	NC score	0.115423 (rank : 1340)
Query Neighborhood Hits	1371	Target Neighborhood Hits	986	Shared Neighborhood Hits	283
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	2.36792 (rank : 1159)	NC score	0.118237 (rank : 1314)
Query Neighborhood Hits	1371	Target Neighborhood Hits	958	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

STIM2_HUMAN
θ value	2.36792 (rank : 1160)	NC score	0.224448 (rank : 771)
Query Neighborhood Hits	1371	Target Neighborhood Hits	420	Shared Neighborhood Hits	322
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

SYT4_MOUSE
θ value	2.36792 (rank : 1161)	NC score	0.148320 (rank : 1106)
Query Neighborhood Hits	1371	Target Neighborhood Hits	123	Shared Neighborhood Hits	81
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

TJAP1_HUMAN
θ value	2.36792 (rank : 1162)	NC score	0.130964 (rank : 1232)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	145
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

ADIP_MOUSE
θ value	3.0926 (rank : 1163)	NC score	0.302887 (rank : 555)
Query Neighborhood Hits	1371	Target Neighborhood Hits	415	Shared Neighborhood Hits	337
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

AMOL1_HUMAN
θ value	3.0926 (rank : 1164)	NC score	0.259151 (rank : 660)
Query Neighborhood Hits	1371	Target Neighborhood Hits	435	Shared Neighborhood Hits	326
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

APLP2_MOUSE
θ value	3.0926 (rank : 1165)	NC score	0.073581 (rank : 1709)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	111
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

CC019_MOUSE
θ value	3.0926 (rank : 1166)	NC score	0.049534 (rank : 2182)
Query Neighborhood Hits	1371	Target Neighborhood Hits	61	Shared Neighborhood Hits	44
SwissProt Accessions	Q3U155, Q80XC8, Q8CA20	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf19 homolog.

CCD22_HUMAN
θ value	3.0926 (rank : 1167)	NC score	0.201254 (rank : 841)
Query Neighborhood Hits	1371	Target Neighborhood Hits	242	Shared Neighborhood Hits	185
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CPLX3_HUMAN
θ value	3.0926 (rank : 1168)	NC score	0.022748 (rank : 2277)
Query Neighborhood Hits	1371	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WVH0, Q8TEM6, Q9H818	Gene names	CPLX3
Domain Architecture	No domain graphic available
Description	Complexin-3 (Complexin III) (CPX III).

CPLX3_MOUSE
θ value	3.0926 (rank : 1169)	NC score	0.022835 (rank : 2276)
Query Neighborhood Hits	1371	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R1B5, Q96AW7	Gene names	Cplx3
Domain Architecture	No domain graphic available
Description	Complexin-3 (Complexin III) (CPX III).

CU013_HUMAN
θ value	3.0926 (rank : 1170)	NC score	0.332597 (rank : 498)
Query Neighborhood Hits	1371	Target Neighborhood Hits	405	Shared Neighborhood Hits	314
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

DAAM1_HUMAN
θ value	3.0926 (rank : 1171)	NC score	0.149045 (rank : 1099)
Query Neighborhood Hits	1371	Target Neighborhood Hits	483	Shared Neighborhood Hits	296
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

E41L2_MOUSE
θ value	3.0926 (rank : 1172)	NC score	0.068504 (rank : 1771)
Query Neighborhood Hits	1371	Target Neighborhood Hits	459	Shared Neighborhood Hits	188
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FES_MOUSE
θ value	3.0926 (rank : 1173)	NC score	0.076186 (rank : 1675)
Query Neighborhood Hits	1371	Target Neighborhood Hits	980	Shared Neighborhood Hits	203
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

GRP75_HUMAN
θ value	3.0926 (rank : 1174)	NC score	0.020707 (rank : 2284)
Query Neighborhood Hits	1371	Target Neighborhood Hits	97	Shared Neighborhood Hits	52
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

ING3_HUMAN
θ value	3.0926 (rank : 1175)	NC score	0.063926 (rank : 1824)
Query Neighborhood Hits	1371	Target Neighborhood Hits	178	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_MOUSE
θ value	3.0926 (rank : 1176)	NC score	0.068883 (rank : 1766)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

K2C1B_HUMAN
θ value	3.0926 (rank : 1177)	NC score	0.172458 (rank : 970)
Query Neighborhood Hits	1371	Target Neighborhood Hits	542	Shared Neighborhood Hits	376
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

KIFA3_HUMAN
θ value	3.0926 (rank : 1178)	NC score	0.018111 (rank : 2293)
Query Neighborhood Hits	1371	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

KIFA3_MOUSE
θ value	3.0926 (rank : 1179)	NC score	0.018243 (rank : 2292)
Query Neighborhood Hits	1371	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

LAP2_MOUSE
θ value	3.0926 (rank : 1180)	NC score	0.004811 (rank : 2330)
Query Neighborhood Hits	1371	Target Neighborhood Hits	482	Shared Neighborhood Hits	59
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MAP9_MOUSE
θ value	3.0926 (rank : 1181)	NC score	0.282955 (rank : 602)
Query Neighborhood Hits	1371	Target Neighborhood Hits	529	Shared Neighborhood Hits	325
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MEFV_HUMAN
θ value	3.0926 (rank : 1182)	NC score	0.034500 (rank : 2237)
Query Neighborhood Hits	1371	Target Neighborhood Hits	431	Shared Neighborhood Hits	146
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

REN3B_HUMAN
θ value	3.0926 (rank : 1183)	NC score	0.311048 (rank : 540)
Query Neighborhood Hits	1371	Target Neighborhood Hits	412	Shared Neighborhood Hits	301
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RHBD4_HUMAN
θ value	3.0926 (rank : 1184)	NC score	0.014682 (rank : 2301)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	P58872	Gene names	RHBDL4, VRHO
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

RX_HUMAN
θ value	3.0926 (rank : 1185)	NC score	-0.009516 (rank : 2352)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SKI_MOUSE
θ value	3.0926 (rank : 1186)	NC score	0.254277 (rank : 678)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	324
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

TNIP3_HUMAN
θ value	3.0926 (rank : 1187)	NC score	0.424485 (rank : 284)
Query Neighborhood Hits	1371	Target Neighborhood Hits	511	Shared Neighborhood Hits	402
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TRAF5_HUMAN
θ value	3.0926 (rank : 1188)	NC score	0.111420 (rank : 1372)
Query Neighborhood Hits	1371	Target Neighborhood Hits	396	Shared Neighborhood Hits	220
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRI35_HUMAN
θ value	3.0926 (rank : 1189)	NC score	0.034828 (rank : 2231)
Query Neighborhood Hits	1371	Target Neighborhood Hits	382	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

ZN148_HUMAN
θ value	3.0926 (rank : 1190)	NC score	-0.023660 (rank : 2355)
Query Neighborhood Hits	1371	Target Neighborhood Hits	747	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQR1, O00389, O43591	Gene names	ZNF148, ZBP89
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89).

ZN546_HUMAN
θ value	3.0926 (rank : 1191)	NC score	-0.024103 (rank : 2357)
Query Neighborhood Hits	1371	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UE3	Gene names	ZNF546, ZNF49
Domain Architecture	No domain graphic available
Description	Zinc finger protein 546.

ADCY6_HUMAN
θ value	4.03905 (rank : 1192)	NC score	-0.002050 (rank : 2344)
Query Neighborhood Hits	1371	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	O43306, Q9NR75	Gene names	ADCY6, KIAA0422
Domain Architecture
Description	Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6) (Ca(2+)-inhibitable adenylyl cyclase).

AKAP2_MOUSE
θ value	4.03905 (rank : 1193)	NC score	0.103259 (rank : 1435)
Query Neighborhood Hits	1371	Target Neighborhood Hits	385	Shared Neighborhood Hits	161
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

AL2SB_HUMAN
θ value	4.03905 (rank : 1194)	NC score	0.313551 (rank : 536)
Query Neighborhood Hits	1371	Target Neighborhood Hits	294	Shared Neighborhood Hits	241
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

AMOL2_HUMAN
θ value	4.03905 (rank : 1195)	NC score	0.326505 (rank : 507)
Query Neighborhood Hits	1371	Target Neighborhood Hits	603	Shared Neighborhood Hits	419
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

ANGP4_MOUSE
θ value	4.03905 (rank : 1196)	NC score	0.074157 (rank : 1702)
Query Neighborhood Hits	1371	Target Neighborhood Hits	220	Shared Neighborhood Hits	146
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ATRIP_HUMAN
θ value	4.03905 (rank : 1197)	NC score	0.146849 (rank : 1119)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	194
SwissProt Accessions	Q8WXE1, Q8NHQ2, Q8WUG7, Q96CL3, Q9HA30	Gene names	ATRIP
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

CAC1B_MOUSE
θ value	4.03905 (rank : 1198)	NC score	0.002586 (rank : 2335)
Query Neighborhood Hits	1371	Target Neighborhood Hits	351	Shared Neighborhood Hits	43
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CD2L2_HUMAN
θ value	4.03905 (rank : 1199)	NC score	0.095599 (rank : 1491)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1439	Shared Neighborhood Hits	429
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

COVA1_HUMAN
θ value	4.03905 (rank : 1200)	NC score	0.283836 (rank : 597)
Query Neighborhood Hits	1371	Target Neighborhood Hits	416	Shared Neighborhood Hits	298
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

DAAM2_HUMAN
θ value	4.03905 (rank : 1201)	NC score	0.104258 (rank : 1428)
Query Neighborhood Hits	1371	Target Neighborhood Hits	350	Shared Neighborhood Hits	232
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DDX49_HUMAN
θ value	4.03905 (rank : 1202)	NC score	0.010981 (rank : 2314)
Query Neighborhood Hits	1371	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DHX36_MOUSE
θ value	4.03905 (rank : 1203)	NC score	0.011995 (rank : 2309)
Query Neighborhood Hits	1371	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DREB_MOUSE
θ value	4.03905 (rank : 1204)	NC score	0.240371 (rank : 727)
Query Neighborhood Hits	1371	Target Neighborhood Hits	446	Shared Neighborhood Hits	301
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

IF37_HUMAN
θ value	4.03905 (rank : 1205)	NC score	0.024128 (rank : 2270)
Query Neighborhood Hits	1371	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O15371, Q5M9Q6	Gene names	EIF3S7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).

IF37_MOUSE
θ value	4.03905 (rank : 1206)	NC score	0.035658 (rank : 2227)
Query Neighborhood Hits	1371	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	O70194	Gene names	Eif3s7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).

ITCH_MOUSE
θ value	4.03905 (rank : 1207)	NC score	0.030615 (rank : 2250)
Query Neighborhood Hits	1371	Target Neighborhood Hits	127	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

K1C18_MOUSE
θ value	4.03905 (rank : 1208)	NC score	0.151066 (rank : 1090)
Query Neighborhood Hits	1371	Target Neighborhood Hits	386	Shared Neighborhood Hits	296
SwissProt Accessions	P05784, Q61766	Gene names	Krt18, Kerd, Krt1-18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18) (Cytokeratin endo B) (Keratin D).

KGP2_HUMAN
θ value	4.03905 (rank : 1209)	NC score	0.059300 (rank : 1896)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1023	Shared Neighborhood Hits	209
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KI18A_MOUSE
θ value	4.03905 (rank : 1210)	NC score	0.100452 (rank : 1459)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	142
SwissProt Accessions	Q91WD7, Q3TP77, Q8BLL1	Gene names	Kif18a
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

KIF1A_HUMAN
θ value	4.03905 (rank : 1211)	NC score	0.092733 (rank : 1519)
Query Neighborhood Hits	1371	Target Neighborhood Hits	240	Shared Neighborhood Hits	150
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1A_MOUSE
θ value	4.03905 (rank : 1212)	NC score	0.092222 (rank : 1525)
Query Neighborhood Hits	1371	Target Neighborhood Hits	239	Shared Neighborhood Hits	146
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

LMD1_HUMAN
θ value	4.03905 (rank : 1213)	NC score	0.024574 (rank : 2268)
Query Neighborhood Hits	1371	Target Neighborhood Hits	169	Shared Neighborhood Hits	52
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

MPP4_HUMAN
θ value	4.03905 (rank : 1214)	NC score	0.095924 (rank : 1489)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	90
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MRCKG_MOUSE
θ value	4.03905 (rank : 1215)	NC score	0.176047 (rank : 946)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1466	Shared Neighborhood Hits	547
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

NEK11_HUMAN
θ value	4.03905 (rank : 1216)	NC score	0.071865 (rank : 1733)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1043	Shared Neighborhood Hits	231
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

PCD15_HUMAN
θ value	4.03905 (rank : 1217)	NC score	-0.006009 (rank : 2348)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PRP4B_MOUSE
θ value	4.03905 (rank : 1218)	NC score	0.066319 (rank : 1800)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1040	Shared Neighborhood Hits	220
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

PTPRZ_HUMAN
θ value	4.03905 (rank : 1219)	NC score	-0.007264 (rank : 2350)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

RABE2_MOUSE
θ value	4.03905 (rank : 1220)	NC score	0.390416 (rank : 384)
Query Neighborhood Hits	1371	Target Neighborhood Hits	598	Shared Neighborhood Hits	436
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RP9_HUMAN
θ value	4.03905 (rank : 1221)	NC score	0.020674 (rank : 2285)
Query Neighborhood Hits	1371	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TA86	Gene names	RP9
Domain Architecture	No domain graphic available
Description	Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1).

SEC62_HUMAN
θ value	4.03905 (rank : 1222)	NC score	0.026147 (rank : 2264)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

STXB1_HUMAN
θ value	4.03905 (rank : 1223)	NC score	0.005433 (rank : 2327)
Query Neighborhood Hits	1371	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	P61764, Q28208, Q62759, Q64320, Q96TG8	Gene names	STXBP1, UNC18A
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (p67).

STXB1_MOUSE
θ value	4.03905 (rank : 1224)	NC score	0.005433 (rank : 2328)
Query Neighborhood Hits	1371	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	O08599, Q8VD51	Gene names	Stxbp1
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1).

T3JAM_MOUSE
θ value	4.03905 (rank : 1225)	NC score	0.365644 (rank : 430)
Query Neighborhood Hits	1371	Target Neighborhood Hits	535	Shared Neighborhood Hits	386
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TEKT2_MOUSE
θ value	4.03905 (rank : 1226)	NC score	0.171346 (rank : 977)
Query Neighborhood Hits	1371	Target Neighborhood Hits	199	Shared Neighborhood Hits	161
SwissProt Accessions	Q922G7, Q9WVR0	Gene names	Tekt2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t).

TRI60_HUMAN
θ value	4.03905 (rank : 1227)	NC score	0.026464 (rank : 2263)
Query Neighborhood Hits	1371	Target Neighborhood Hits	357	Shared Neighborhood Hits	108
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TTC5_HUMAN
θ value	4.03905 (rank : 1228)	NC score	0.015180 (rank : 2297)
Query Neighborhood Hits	1371	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N0Z6	Gene names	TTC5
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 5 (TPR repeat protein 5).

U2AFM_MOUSE
θ value	4.03905 (rank : 1229)	NC score	0.275680 (rank : 622)
Query Neighborhood Hits	1371	Target Neighborhood Hits	543	Shared Neighborhood Hits	404
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

AAT1_HUMAN
θ value	5.27518 (rank : 1230)	NC score	0.174970 (rank : 954)
Query Neighborhood Hits	1371	Target Neighborhood Hits	199	Shared Neighborhood Hits	161
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

ANLN_MOUSE
θ value	5.27518 (rank : 1231)	NC score	0.090065 (rank : 1539)
Query Neighborhood Hits	1371	Target Neighborhood Hits	297	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

BAP29_HUMAN
θ value	5.27518 (rank : 1232)	NC score	0.215482 (rank : 803)
Query Neighborhood Hits	1371	Target Neighborhood Hits	362	Shared Neighborhood Hits	274
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

BAZ1A_HUMAN
θ value	5.27518 (rank : 1233)	NC score	0.188122 (rank : 883)
Query Neighborhood Hits	1371	Target Neighborhood Hits	693	Shared Neighborhood Hits	397
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_MOUSE
θ value	5.27518 (rank : 1234)	NC score	0.070771 (rank : 1743)
Query Neighborhood Hits	1371	Target Neighborhood Hits	394	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BRD4_HUMAN
θ value	5.27518 (rank : 1235)	NC score	0.101052 (rank : 1456)
Query Neighborhood Hits	1371	Target Neighborhood Hits	851	Shared Neighborhood Hits	292
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	5.27518 (rank : 1236)	NC score	0.114898 (rank : 1345)
Query Neighborhood Hits	1371	Target Neighborhood Hits	845	Shared Neighborhood Hits	315
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CETN1_HUMAN
θ value	5.27518 (rank : 1237)	NC score	0.032870 (rank : 2241)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CKAP4_HUMAN
θ value	5.27518 (rank : 1238)	NC score	0.386067 (rank : 392)
Query Neighborhood Hits	1371	Target Neighborhood Hits	592	Shared Neighborhood Hits	400
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

DACH1_HUMAN
θ value	5.27518 (rank : 1239)	NC score	0.048725 (rank : 2184)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DGKK_HUMAN
θ value	5.27518 (rank : 1240)	NC score	0.024168 (rank : 2269)
Query Neighborhood Hits	1371	Target Neighborhood Hits	378	Shared Neighborhood Hits	67
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DMPK_MOUSE
θ value	5.27518 (rank : 1241)	NC score	0.061466 (rank : 1858)
Query Neighborhood Hits	1371	Target Neighborhood Hits	908	Shared Neighborhood Hits	156
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

DPP10_HUMAN
θ value	5.27518 (rank : 1242)	NC score	-0.000051 (rank : 2341)
Query Neighborhood Hits	1371	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

DTNB_MOUSE
θ value	5.27518 (rank : 1243)	NC score	0.098944 (rank : 1468)
Query Neighborhood Hits	1371	Target Neighborhood Hits	263	Shared Neighborhood Hits	168
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

FMN1A_MOUSE
θ value	5.27518 (rank : 1244)	NC score	0.042705 (rank : 2209)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	127
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	5.27518 (rank : 1245)	NC score	0.040811 (rank : 2214)
Query Neighborhood Hits	1371	Target Neighborhood Hits	447	Shared Neighborhood Hits	115
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

GP73_HUMAN
θ value	5.27518 (rank : 1246)	NC score	0.221124 (rank : 785)
Query Neighborhood Hits	1371	Target Neighborhood Hits	309	Shared Neighborhood Hits	230
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

IFRD1_HUMAN
θ value	5.27518 (rank : 1247)	NC score	0.008101 (rank : 2320)
Query Neighborhood Hits	1371	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O00458, O75234, Q5U013, Q9BVE4	Gene names	IFRD1
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4).

IMMT_HUMAN
θ value	5.27518 (rank : 1248)	NC score	0.310395 (rank : 541)
Query Neighborhood Hits	1371	Target Neighborhood Hits	494	Shared Neighborhood Hits	362
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

K2C6B_HUMAN
θ value	5.27518 (rank : 1249)	NC score	0.182277 (rank : 910)
Query Neighborhood Hits	1371	Target Neighborhood Hits	526	Shared Neighborhood Hits	395
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C6E_HUMAN
θ value	5.27518 (rank : 1250)	NC score	0.182222 (rank : 911)
Query Neighborhood Hits	1371	Target Neighborhood Hits	516	Shared Neighborhood Hits	387
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

KIF17_HUMAN
θ value	5.27518 (rank : 1251)	NC score	0.117330 (rank : 1318)
Query Neighborhood Hits	1371	Target Neighborhood Hits	365	Shared Neighborhood Hits	237
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

LMNB2_MOUSE
θ value	5.27518 (rank : 1252)	NC score	0.297577 (rank : 572)
Query Neighborhood Hits	1371	Target Neighborhood Hits	674	Shared Neighborhood Hits	468
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

MK06_HUMAN
θ value	5.27518 (rank : 1253)	NC score	0.038457 (rank : 2220)
Query Neighborhood Hits	1371	Target Neighborhood Hits	815	Shared Neighborhood Hits	101
SwissProt Accessions	Q16659, Q68DH4, Q8IYN8	Gene names	MAPK6, ERK3, PRKM6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97- MAPK).

MYST4_MOUSE
θ value	5.27518 (rank : 1254)	NC score	0.021925 (rank : 2281)
Query Neighborhood Hits	1371	Target Neighborhood Hits	416	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

OTU6B_MOUSE
θ value	5.27518 (rank : 1255)	NC score	0.139161 (rank : 1168)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	171
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

PDCL2_HUMAN
θ value	5.27518 (rank : 1256)	NC score	0.011544 (rank : 2310)
Query Neighborhood Hits	1371	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N4E4	Gene names	PDCL2
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 2.

POF1B_HUMAN
θ value	5.27518 (rank : 1257)	NC score	0.350667 (rank : 469)
Query Neighborhood Hits	1371	Target Neighborhood Hits	494	Shared Neighborhood Hits	375
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

PPIP2_MOUSE
θ value	5.27518 (rank : 1258)	NC score	0.222690 (rank : 776)
Query Neighborhood Hits	1371	Target Neighborhood Hits	308	Shared Neighborhood Hits	244
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PRVA_MOUSE
θ value	5.27518 (rank : 1259)	NC score	0.043044 (rank : 2208)
Query Neighborhood Hits	1371	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

RBM25_HUMAN
θ value	5.27518 (rank : 1260)	NC score	0.398526 (rank : 361)
Query Neighborhood Hits	1371	Target Neighborhood Hits	682	Shared Neighborhood Hits	420
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RHBD4_MOUSE
θ value	5.27518 (rank : 1261)	NC score	0.013412 (rank : 2304)
Query Neighborhood Hits	1371	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P58873	Gene names	Rhbdl4, Vrho
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

RHG25_HUMAN
θ value	5.27518 (rank : 1262)	NC score	0.170261 (rank : 982)
Query Neighborhood Hits	1371	Target Neighborhood Hits	550	Shared Neighborhood Hits	318
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RIF1_MOUSE
θ value	5.27518 (rank : 1263)	NC score	0.046777 (rank : 2190)
Query Neighborhood Hits	1371	Target Neighborhood Hits	315	Shared Neighborhood Hits	104
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

RRMJ3_MOUSE
θ value	5.27518 (rank : 1264)	NC score	0.078630 (rank : 1653)
Query Neighborhood Hits	1371	Target Neighborhood Hits	163	Shared Neighborhood Hits	103
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

S3TC2_HUMAN
θ value	5.27518 (rank : 1265)	NC score	0.033033 (rank : 2240)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TF17, Q9H8I5	Gene names	SH3TC2, KIAA1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

SETD2_HUMAN
θ value	5.27518 (rank : 1266)	NC score	0.037464 (rank : 2224)
Query Neighborhood Hits	1371	Target Neighborhood Hits	412	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SKI_HUMAN
θ value	5.27518 (rank : 1267)	NC score	0.245472 (rank : 710)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	335
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

SYTL2_MOUSE
θ value	5.27518 (rank : 1268)	NC score	0.133630 (rank : 1205)
Query Neighborhood Hits	1371	Target Neighborhood Hits	253	Shared Neighborhood Hits	98
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TRAK2_HUMAN
θ value	5.27518 (rank : 1269)	NC score	0.335746 (rank : 493)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	358
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

TRI34_HUMAN
θ value	5.27518 (rank : 1270)	NC score	0.058698 (rank : 1905)
Query Neighborhood Hits	1371	Target Neighborhood Hits	416	Shared Neighborhood Hits	189
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI39_HUMAN
θ value	5.27518 (rank : 1271)	NC score	0.088300 (rank : 1556)
Query Neighborhood Hits	1371	Target Neighborhood Hits	693	Shared Neighborhood Hits	336
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	5.27518 (rank : 1272)	NC score	0.090202 (rank : 1538)
Query Neighborhood Hits	1371	Target Neighborhood Hits	691	Shared Neighborhood Hits	336
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM4_HUMAN
θ value	5.27518 (rank : 1273)	NC score	0.018817 (rank : 2291)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	73
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

UBE4A_HUMAN
θ value	5.27518 (rank : 1274)	NC score	0.011108 (rank : 2313)
Query Neighborhood Hits	1371	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q14139, Q6P5T4, Q7Z639	Gene names	UBE4A, KIAA0126
Domain Architecture	No domain graphic available
Description	Ubiquitin conjugation factor E4 A.

UTP11_MOUSE
θ value	5.27518 (rank : 1275)	NC score	0.058913 (rank : 1902)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CZJ1, Q3UI21, Q9CVB5	Gene names	Utp11l
Domain Architecture
Description	Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA- associated protein 11) (UTP11-like protein).

ZCPW1_MOUSE
θ value	5.27518 (rank : 1276)	NC score	0.037763 (rank : 2222)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	79
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ZN365_MOUSE
θ value	5.27518 (rank : 1277)	NC score	0.129071 (rank : 1239)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	145
SwissProt Accessions	Q8BG89, Q80TQ4, Q8BK39, Q8BXT2	Gene names	Znf365, Kiaa0844, Zfp365
Domain Architecture	No domain graphic available
Description	Protein ZNF365 (Su48).

ZRF1_MOUSE
θ value	5.27518 (rank : 1278)	NC score	0.244659 (rank : 713)
Query Neighborhood Hits	1371	Target Neighborhood Hits	414	Shared Neighborhood Hits	283
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

A4_HUMAN
θ value	6.88961 (rank : 1279)	NC score	0.087272 (rank : 1565)
Query Neighborhood Hits	1371	Target Neighborhood Hits	274	Shared Neighborhood Hits	181
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

AFF2_MOUSE
θ value	6.88961 (rank : 1280)	NC score	0.015146 (rank : 2298)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

AHR_HUMAN
θ value	6.88961 (rank : 1281)	NC score	-0.000676 (rank : 2343)
Query Neighborhood Hits	1371	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

ASPM_MOUSE
θ value	6.88961 (rank : 1282)	NC score	0.036417 (rank : 2226)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

BAP29_MOUSE
θ value	6.88961 (rank : 1283)	NC score	0.196575 (rank : 855)
Query Neighborhood Hits	1371	Target Neighborhood Hits	285	Shared Neighborhood Hits	225
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

CABP3_HUMAN
θ value	6.88961 (rank : 1284)	NC score	0.029700 (rank : 2254)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP4_MOUSE
θ value	6.88961 (rank : 1285)	NC score	0.030900 (rank : 2247)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CABP5_HUMAN
θ value	6.88961 (rank : 1286)	NC score	0.029177 (rank : 2255)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CAR10_MOUSE
θ value	6.88961 (rank : 1287)	NC score	0.269804 (rank : 637)
Query Neighborhood Hits	1371	Target Neighborhood Hits	407	Shared Neighborhood Hits	323
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

CHCH3_MOUSE
θ value	6.88961 (rank : 1288)	NC score	0.160410 (rank : 1034)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	202
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CN120_HUMAN
θ value	6.88961 (rank : 1289)	NC score	0.011392 (rank : 2311)
Query Neighborhood Hits	1371	Target Neighborhood Hits	25	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEJ9, Q9Y400	Gene names	C14orf120
Domain Architecture
Description	Protein C14orf120.

CN140_HUMAN
θ value	6.88961 (rank : 1290)	NC score	0.037689 (rank : 2223)
Query Neighborhood Hits	1371	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q53FD0, Q9BTA8, Q9H5S9	Gene names	C14orf140
Domain Architecture	No domain graphic available
Description	Protein C14orf140.

CROP_HUMAN
θ value	6.88961 (rank : 1291)	NC score	0.221423 (rank : 782)
Query Neighborhood Hits	1371	Target Neighborhood Hits	402	Shared Neighborhood Hits	269
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
θ value	6.88961 (rank : 1292)	NC score	0.215718 (rank : 802)
Query Neighborhood Hits	1371	Target Neighborhood Hits	403	Shared Neighborhood Hits	268
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CRSP2_HUMAN
θ value	6.88961 (rank : 1293)	NC score	0.012962 (rank : 2305)
Query Neighborhood Hits	1371	Target Neighborhood Hits	380	Shared Neighborhood Hits	41
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CS029_HUMAN
θ value	6.88961 (rank : 1294)	NC score	0.157532 (rank : 1057)
Query Neighborhood Hits	1371	Target Neighborhood Hits	329	Shared Neighborhood Hits	231
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

DMRTA_HUMAN
θ value	6.88961 (rank : 1295)	NC score	0.003577 (rank : 2331)
Query Neighborhood Hits	1371	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

DREB_HUMAN
θ value	6.88961 (rank : 1296)	NC score	0.236035 (rank : 737)
Query Neighborhood Hits	1371	Target Neighborhood Hits	450	Shared Neighborhood Hits	307
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GIMA4_HUMAN
θ value	6.88961 (rank : 1297)	NC score	0.105672 (rank : 1420)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NUV9	Gene names	GIMAP4, IAN1, IMAP4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1).

GIMA7_HUMAN
θ value	6.88961 (rank : 1298)	NC score	0.046370 (rank : 2195)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NHV1	Gene names	GIMAP7, IAN7
Domain Architecture	No domain graphic available
Description	GTPase, IMAP family member 7 (Immunity-associated nucleotide 7 protein).

GON4L_HUMAN
θ value	6.88961 (rank : 1299)	NC score	0.043664 (rank : 2206)
Query Neighborhood Hits	1371	Target Neighborhood Hits	555	Shared Neighborhood Hits	132
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IF39_HUMAN
θ value	6.88961 (rank : 1300)	NC score	0.022204 (rank : 2279)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	34
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

KIF2C_HUMAN
θ value	6.88961 (rank : 1301)	NC score	0.074737 (rank : 1694)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	81
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

LSD1_HUMAN
θ value	6.88961 (rank : 1302)	NC score	0.052093 (rank : 2098)
Query Neighborhood Hits	1371	Target Neighborhood Hits	455	Shared Neighborhood Hits	128
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	6.88961 (rank : 1303)	NC score	0.053780 (rank : 2025)
Query Neighborhood Hits	1371	Target Neighborhood Hits	224	Shared Neighborhood Hits	116
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MIPO1_HUMAN
θ value	6.88961 (rank : 1304)	NC score	0.388935 (rank : 385)
Query Neighborhood Hits	1371	Target Neighborhood Hits	486	Shared Neighborhood Hits	380
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MITF_HUMAN
θ value	6.88961 (rank : 1305)	NC score	0.007996 (rank : 2321)
Query Neighborhood Hits	1371	Target Neighborhood Hits	113	Shared Neighborhood Hits	25
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MORC1_HUMAN
θ value	6.88961 (rank : 1306)	NC score	0.053968 (rank : 2019)
Query Neighborhood Hits	1371	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q86VD1, Q7L8E2, Q9NSG7, Q9Y6D4	Gene names	MORC1, MORC
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 1.

NEST_HUMAN
θ value	6.88961 (rank : 1307)	NC score	0.369811 (rank : 420)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1305	Shared Neighborhood Hits	572
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PESC_HUMAN
θ value	6.88961 (rank : 1308)	NC score	0.025096 (rank : 2265)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	O00541, Q6IC29	Gene names	PES1
Domain Architecture
Description	Pescadillo homolog 1.

PHLB1_MOUSE
θ value	6.88961 (rank : 1309)	NC score	0.254164 (rank : 680)
Query Neighborhood Hits	1371	Target Neighborhood Hits	678	Shared Neighborhood Hits	361
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PLSL_HUMAN
θ value	6.88961 (rank : 1310)	NC score	0.051052 (rank : 2144)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	61
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

PLSL_MOUSE
θ value	6.88961 (rank : 1311)	NC score	0.055993 (rank : 1967)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	64
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

RBM5_MOUSE
θ value	6.88961 (rank : 1312)	NC score	0.012388 (rank : 2308)
Query Neighborhood Hits	1371	Target Neighborhood Hits	216	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YE7, Q3UZ19, Q99KV9	Gene names	Rbm5, Luca15
Domain Architecture	No domain graphic available
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15).

RCAS1_HUMAN
θ value	6.88961 (rank : 1313)	NC score	0.008677 (rank : 2318)
Query Neighborhood Hits	1371	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	O00559, Q6IB20, Q9BS76	Gene names	EBAG9, RCAS1
Domain Architecture	No domain graphic available
Description	Receptor-binding cancer antigen expressed on SiSo cells (Cancer- associated surface antigen RCAS1) (Estrogen receptor-binding fragment- associated gene 9 protein).

RPOM_MOUSE
θ value	6.88961 (rank : 1314)	NC score	0.014814 (rank : 2300)
Query Neighborhood Hits	1371	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BKF1, Q8BJE0	Gene names	Polrmt
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase, mitochondrial precursor (EC 2.7.7.6) (MtRPOL).

RRP5_HUMAN
θ value	6.88961 (rank : 1315)	NC score	0.063928 (rank : 1823)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	121
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

SEP10_HUMAN
θ value	6.88961 (rank : 1316)	NC score	0.038012 (rank : 2221)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	101
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

SETB1_MOUSE
θ value	6.88961 (rank : 1317)	NC score	0.010097 (rank : 2317)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	36
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SN1L1_MOUSE
θ value	6.88961 (rank : 1318)	NC score	0.042458 (rank : 2210)
Query Neighborhood Hits	1371	Target Neighborhood Hits	895	Shared Neighborhood Hits	99
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

TCF20_MOUSE
θ value	6.88961 (rank : 1319)	NC score	0.019419 (rank : 2289)
Query Neighborhood Hits	1371	Target Neighborhood Hits	396	Shared Neighborhood Hits	70
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TFAM_HUMAN
θ value	6.88961 (rank : 1320)	NC score	0.045454 (rank : 2199)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

TRIM6_MOUSE
θ value	6.88961 (rank : 1321)	NC score	0.046699 (rank : 2191)
Query Neighborhood Hits	1371	Target Neighborhood Hits	451	Shared Neighborhood Hits	193
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

UBF1_MOUSE
θ value	6.88961 (rank : 1322)	NC score	0.075457 (rank : 1684)
Query Neighborhood Hits	1371	Target Neighborhood Hits	419	Shared Neighborhood Hits	156
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

UBP8_HUMAN
θ value	6.88961 (rank : 1323)	NC score	0.128770 (rank : 1246)
Query Neighborhood Hits	1371	Target Neighborhood Hits	751	Shared Neighborhood Hits	403
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

YYAP1_HUMAN
θ value	6.88961 (rank : 1324)	NC score	0.010266 (rank : 2315)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H869, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, Q8IXA6, Q8TEW5, Q8TF04, Q96HB6, Q9BQ64, Q9NV84	Gene names	YY1AP1, HCCA2, YY1AP
Domain Architecture	No domain graphic available
Description	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2).

ADDB_MOUSE
θ value	8.99809 (rank : 1325)	NC score	0.023833 (rank : 2271)
Query Neighborhood Hits	1371	Target Neighborhood Hits	574	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ATM_MOUSE
θ value	8.99809 (rank : 1326)	NC score	0.015009 (rank : 2299)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q62388	Gene names	Atm
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).

CDKL5_HUMAN
θ value	8.99809 (rank : 1327)	NC score	0.040567 (rank : 2215)
Query Neighborhood Hits	1371	Target Neighborhood Hits	967	Shared Neighborhood Hits	118
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CU005_HUMAN
θ value	8.99809 (rank : 1328)	NC score	0.005658 (rank : 2326)
Query Neighborhood Hits	1371	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3R5, Q9UEZ3	Gene names	C21orf5, KIAA0933
Domain Architecture
Description	Protein C21orf5.

DCJ11_HUMAN
θ value	8.99809 (rank : 1329)	NC score	0.001432 (rank : 2337)
Query Neighborhood Hits	1371	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NVH1, Q4VWF5, Q5VZN0, Q6PK20, Q6PK70, Q8NDM2, Q96CL7	Gene names	DNAJC11
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 11.

FAK2_MOUSE
θ value	8.99809 (rank : 1330)	NC score	0.060664 (rank : 1870)
Query Neighborhood Hits	1371	Target Neighborhood Hits	851	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

GCP60_HUMAN
θ value	8.99809 (rank : 1331)	NC score	0.246708 (rank : 705)
Query Neighborhood Hits	1371	Target Neighborhood Hits	419	Shared Neighborhood Hits	307
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

IF2M_MOUSE
θ value	8.99809 (rank : 1332)	NC score	0.028135 (rank : 2259)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	77
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

ITCH_HUMAN
θ value	8.99809 (rank : 1333)	NC score	0.027565 (rank : 2260)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	40
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

JHD2C_HUMAN
θ value	8.99809 (rank : 1334)	NC score	0.017634 (rank : 2294)
Query Neighborhood Hits	1371	Target Neighborhood Hits	279	Shared Neighborhood Hits	80
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

K0494_MOUSE
θ value	8.99809 (rank : 1335)	NC score	0.210488 (rank : 818)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	179
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

K0586_HUMAN
θ value	8.99809 (rank : 1336)	NC score	0.164380 (rank : 1016)
Query Neighborhood Hits	1371	Target Neighborhood Hits	311	Shared Neighborhood Hits	172
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

K1C23_MOUSE
θ value	8.99809 (rank : 1337)	NC score	0.148329 (rank : 1105)
Query Neighborhood Hits	1371	Target Neighborhood Hits	370	Shared Neighborhood Hits	287
SwissProt Accessions	Q99PS0	Gene names	Krt23, Haik1, Krt1-23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

KIF3C_HUMAN
θ value	8.99809 (rank : 1338)	NC score	0.211530 (rank : 813)
Query Neighborhood Hits	1371	Target Neighborhood Hits	478	Shared Neighborhood Hits	370
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

KLRA2_MOUSE
θ value	8.99809 (rank : 1339)	NC score	0.001367 (rank : 2338)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q60660	Gene names	Klra2, Ly49-b, Ly49b
Domain Architecture
Description	Killer cell lectin-like receptor 2 (T-cell surface glycoprotein Ly- 49B) (Ly49-B antigen) (Lymphocyte antigen 49B).

LMO7_HUMAN
θ value	8.99809 (rank : 1340)	NC score	0.188353 (rank : 882)
Query Neighborhood Hits	1371	Target Neighborhood Hits	507	Shared Neighborhood Hits	247
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LRRC6_HUMAN
θ value	8.99809 (rank : 1341)	NC score	0.016983 (rank : 2295)
Query Neighborhood Hits	1371	Target Neighborhood Hits	181	Shared Neighborhood Hits	46
SwissProt Accessions	Q86X45, Q13648, Q4G183	Gene names	LRRC6, LRTP, TSLRP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

MNDA_HUMAN
θ value	8.99809 (rank : 1342)	NC score	0.007706 (rank : 2322)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	27
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

MXI1_MOUSE
θ value	8.99809 (rank : 1343)	NC score	0.018870 (rank : 2290)
Query Neighborhood Hits	1371	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MYO15_MOUSE
θ value	8.99809 (rank : 1344)	NC score	0.128399 (rank : 1251)
Query Neighborhood Hits	1371	Target Neighborhood Hits	467	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NBN_HUMAN
θ value	8.99809 (rank : 1345)	NC score	0.077192 (rank : 1665)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	110
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

NGAP_HUMAN
θ value	8.99809 (rank : 1346)	NC score	0.185444 (rank : 897)
Query Neighborhood Hits	1371	Target Neighborhood Hits	517	Shared Neighborhood Hits	351
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

NONO_HUMAN
θ value	8.99809 (rank : 1347)	NC score	0.123891 (rank : 1274)
Query Neighborhood Hits	1371	Target Neighborhood Hits	441	Shared Neighborhood Hits	209
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

NONO_MOUSE
θ value	8.99809 (rank : 1348)	NC score	0.123134 (rank : 1278)
Query Neighborhood Hits	1371	Target Neighborhood Hits	444	Shared Neighborhood Hits	209
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

P73L_HUMAN
θ value	8.99809 (rank : 1349)	NC score	0.005885 (rank : 2325)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

P73L_MOUSE
θ value	8.99809 (rank : 1350)	NC score	0.005243 (rank : 2329)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).

PDZD2_HUMAN
θ value	8.99809 (rank : 1351)	NC score	0.041268 (rank : 2213)
Query Neighborhood Hits	1371	Target Neighborhood Hits	772	Shared Neighborhood Hits	123
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PERF_HUMAN
θ value	8.99809 (rank : 1352)	NC score	0.026795 (rank : 2262)
Query Neighborhood Hits	1371	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

PLDN_HUMAN
θ value	8.99809 (rank : 1353)	NC score	0.088417 (rank : 1555)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UL45	Gene names	PLDN, PA
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein).

PLDN_MOUSE
θ value	8.99809 (rank : 1354)	NC score	0.043294 (rank : 2207)
Query Neighborhood Hits	1371	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R0C0, Q3TUT4, Q91VG4	Gene names	Pldn, P2, Pa
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein) (Syntaxin 13-interacting protein).

PRC1_HUMAN
θ value	8.99809 (rank : 1355)	NC score	0.237727 (rank : 732)
Query Neighborhood Hits	1371	Target Neighborhood Hits	328	Shared Neighborhood Hits	259
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

RASA1_HUMAN
θ value	8.99809 (rank : 1356)	NC score	0.148408 (rank : 1102)
Query Neighborhood Hits	1371	Target Neighborhood Hits	258	Shared Neighborhood Hits	127
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RCOR2_MOUSE
θ value	8.99809 (rank : 1357)	NC score	0.006136 (rank : 2323)
Query Neighborhood Hits	1371	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

RIPK5_HUMAN
θ value	8.99809 (rank : 1358)	NC score	0.053129 (rank : 2053)
Query Neighborhood Hits	1371	Target Neighborhood Hits	864	Shared Neighborhood Hits	109
SwissProt Accessions	Q6XUX3, O75060, Q5RKT0, Q6IN87, Q6P997, Q86Y03, Q9P1S5	Gene names	RIPK5, KIAA0472, RIP5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase).

RNF31_HUMAN
θ value	8.99809 (rank : 1359)	NC score	0.001598 (rank : 2336)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

SFR17_HUMAN
θ value	8.99809 (rank : 1360)	NC score	0.139420 (rank : 1167)
Query Neighborhood Hits	1371	Target Neighborhood Hits	325	Shared Neighborhood Hits	173
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SNX16_HUMAN
θ value	8.99809 (rank : 1361)	NC score	0.045246 (rank : 2200)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	P57768, Q8N4U3	Gene names	SNX16
Domain Architecture
Description	Sorting nexin-16.

SNX9_HUMAN
θ value	8.99809 (rank : 1362)	NC score	0.156157 (rank : 1065)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

TMCC1_HUMAN
θ value	8.99809 (rank : 1363)	NC score	0.141826 (rank : 1152)
Query Neighborhood Hits	1371	Target Neighborhood Hits	337	Shared Neighborhood Hits	248
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TNIK_HUMAN
θ value	8.99809 (rank : 1364)	NC score	0.148392 (rank : 1103)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1570	Shared Neighborhood Hits	544
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TTC3_HUMAN
θ value	8.99809 (rank : 1365)	NC score	0.285502 (rank : 594)
Query Neighborhood Hits	1371	Target Neighborhood Hits	664	Shared Neighborhood Hits	370
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TXND3_HUMAN
θ value	8.99809 (rank : 1366)	NC score	0.000846 (rank : 2340)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

UBF1_HUMAN
θ value	8.99809 (rank : 1367)	NC score	0.067589 (rank : 1785)
Query Neighborhood Hits	1371	Target Neighborhood Hits	415	Shared Neighborhood Hits	143
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

WDR67_MOUSE
θ value	8.99809 (rank : 1368)	NC score	0.246343 (rank : 707)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	291
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

ZN148_MOUSE
θ value	8.99809 (rank : 1369)	NC score	-0.023836 (rank : 2356)
Query Neighborhood Hits	1371	Target Neighborhood Hits	755	Shared Neighborhood Hits	19
SwissProt Accessions	Q61624, P97475	Gene names	Znf148, Zbp89, Zfp148
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89) (G-rich box-binding protein) (Beta enolase repressor factor 1) (Transcription factor BFCOL1).

ZN365_HUMAN
θ value	8.99809 (rank : 1370)	NC score	0.106030 (rank : 1418)
Query Neighborhood Hits	1371	Target Neighborhood Hits	145	Shared Neighborhood Hits	109
SwissProt Accessions	Q70YC5, O94930, Q5HYE6, Q68SG8, Q6NSK2, Q6P9D4, Q70YC6, Q70YC7	Gene names	ZNF365, KIAA0844
Domain Architecture	No domain graphic available
Description	Protein ZNF365.

ZW10_HUMAN
θ value	8.99809 (rank : 1371)	NC score	0.059316 (rank : 1895)
Query Neighborhood Hits	1371	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	O43264	Gene names	ZW10
Domain Architecture
Description	Centromere/kinetochore protein zw10 homolog.

3BP1_HUMAN
θ value	θ > 10 (rank : 1372)	NC score	0.055035 (rank : 1986)
Query Neighborhood Hits	1371	Target Neighborhood Hits	376	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP5_HUMAN
θ value	θ > 10 (rank : 1373)	NC score	0.276645 (rank : 618)
Query Neighborhood Hits	1371	Target Neighborhood Hits	375	Shared Neighborhood Hits	296
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

3BP5_MOUSE
θ value	θ > 10 (rank : 1374)	NC score	0.267092 (rank : 643)
Query Neighborhood Hits	1371	Target Neighborhood Hits	346	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

A4_MOUSE
θ value	θ > 10 (rank : 1375)	NC score	0.084538 (rank : 1589)
Query Neighborhood Hits	1371	Target Neighborhood Hits	275	Shared Neighborhood Hits	180
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

AATK_HUMAN
θ value	θ > 10 (rank : 1376)	NC score	0.057950 (rank : 1926)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1243	Shared Neighborhood Hits	140
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 1377)	NC score	0.059842 (rank : 1892)
Query Neighborhood Hits	1371	Target Neighborhood Hits	942	Shared Neighborhood Hits	110
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABCF1_HUMAN
θ value	θ > 10 (rank : 1378)	NC score	0.053934 (rank : 2022)
Query Neighborhood Hits	1371	Target Neighborhood Hits	343	Shared Neighborhood Hits	124
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ABCF1_MOUSE
θ value	θ > 10 (rank : 1379)	NC score	0.054529 (rank : 1997)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	113
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABTAP_HUMAN
θ value	θ > 10 (rank : 1380)	NC score	0.160189 (rank : 1037)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	174
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ABTAP_MOUSE
θ value	θ > 10 (rank : 1381)	NC score	0.155906 (rank : 1070)
Query Neighborhood Hits	1371	Target Neighborhood Hits	381	Shared Neighborhood Hits	194
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ACK1_HUMAN
θ value	θ > 10 (rank : 1382)	NC score	0.068957 (rank : 1763)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1140	Shared Neighborhood Hits	166
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	θ > 10 (rank : 1383)	NC score	0.069235 (rank : 1762)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1080	Shared Neighborhood Hits	160
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ACTN1_HUMAN
θ value	θ > 10 (rank : 1384)	NC score	0.076160 (rank : 1677)
Query Neighborhood Hits	1371	Target Neighborhood Hits	221	Shared Neighborhood Hits	133
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	θ > 10 (rank : 1385)	NC score	0.072699 (rank : 1721)
Query Neighborhood Hits	1371	Target Neighborhood Hits	216	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN2_HUMAN
θ value	θ > 10 (rank : 1386)	NC score	0.093896 (rank : 1505)
Query Neighborhood Hits	1371	Target Neighborhood Hits	295	Shared Neighborhood Hits	178
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
θ value	θ > 10 (rank : 1387)	NC score	0.088186 (rank : 1558)
Query Neighborhood Hits	1371	Target Neighborhood Hits	287	Shared Neighborhood Hits	176
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN3_HUMAN
θ value	θ > 10 (rank : 1388)	NC score	0.081684 (rank : 1619)
Query Neighborhood Hits	1371	Target Neighborhood Hits	272	Shared Neighborhood Hits	158
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN4_HUMAN
θ value	θ > 10 (rank : 1389)	NC score	0.100310 (rank : 1461)
Query Neighborhood Hits	1371	Target Neighborhood Hits	279	Shared Neighborhood Hits	174
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	θ > 10 (rank : 1390)	NC score	0.103667 (rank : 1433)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	174
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

AGGF1_HUMAN
θ value	θ > 10 (rank : 1391)	NC score	0.056064 (rank : 1965)
Query Neighborhood Hits	1371	Target Neighborhood Hits	271	Shared Neighborhood Hits	119
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

AINX_HUMAN
θ value	θ > 10 (rank : 1392)	NC score	0.166488 (rank : 1000)
Query Neighborhood Hits	1371	Target Neighborhood Hits	442	Shared Neighborhood Hits	335
SwissProt Accessions	Q16352, Q9BRC5	Gene names	INA
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

AINX_MOUSE
θ value	θ > 10 (rank : 1393)	NC score	0.165133 (rank : 1010)
Query Neighborhood Hits	1371	Target Neighborhood Hits	448	Shared Neighborhood Hits	337
SwissProt Accessions	P46660, Q61958, Q8VCW5	Gene names	Ina
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

AKA12_HUMAN
θ value	θ > 10 (rank : 1394)	NC score	0.123109 (rank : 1279)
Query Neighborhood Hits	1371	Target Neighborhood Hits	825	Shared Neighborhood Hits	251
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AKAP2_HUMAN
θ value	θ > 10 (rank : 1395)	NC score	0.120828 (rank : 1295)
Query Neighborhood Hits	1371	Target Neighborhood Hits	507	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AKAP6_HUMAN
θ value	θ > 10 (rank : 1396)	NC score	0.136823 (rank : 1182)
Query Neighborhood Hits	1371	Target Neighborhood Hits	263	Shared Neighborhood Hits	131
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

ALK_HUMAN
θ value	θ > 10 (rank : 1397)	NC score	0.059219 (rank : 1899)
Query Neighborhood Hits	1371	Target Neighborhood Hits	795	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 1398)	NC score	0.059194 (rank : 1900)
Query Neighborhood Hits	1371	Target Neighborhood Hits	811	Shared Neighborhood Hits	99
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

AMOL1_MOUSE
θ value	θ > 10 (rank : 1399)	NC score	0.227506 (rank : 760)
Query Neighborhood Hits	1371	Target Neighborhood Hits	445	Shared Neighborhood Hits	306
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AMOL2_MOUSE
θ value	θ > 10 (rank : 1400)	NC score	0.325207 (rank : 510)
Query Neighborhood Hits	1371	Target Neighborhood Hits	591	Shared Neighborhood Hits	410
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

AMRP_HUMAN
θ value	θ > 10 (rank : 1401)	NC score	0.090979 (rank : 1533)
Query Neighborhood Hits	1371	Target Neighborhood Hits	126	Shared Neighborhood Hits	101
SwissProt Accessions	P30533	Gene names	LRPAP1, A2MRAP
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP).

ANGP1_HUMAN
θ value	θ > 10 (rank : 1402)	NC score	0.078661 (rank : 1652)
Query Neighborhood Hits	1371	Target Neighborhood Hits	254	Shared Neighborhood Hits	184
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP1_MOUSE
θ value	θ > 10 (rank : 1403)	NC score	0.075237 (rank : 1687)
Query Neighborhood Hits	1371	Target Neighborhood Hits	252	Shared Neighborhood Hits	176
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP2_HUMAN
θ value	θ > 10 (rank : 1404)	NC score	0.130406 (rank : 1236)
Query Neighborhood Hits	1371	Target Neighborhood Hits	400	Shared Neighborhood Hits	283
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP2_MOUSE
θ value	θ > 10 (rank : 1405)	NC score	0.133816 (rank : 1201)
Query Neighborhood Hits	1371	Target Neighborhood Hits	397	Shared Neighborhood Hits	289
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP4_HUMAN
θ value	θ > 10 (rank : 1406)	NC score	0.051430 (rank : 2126)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ANK2_HUMAN
θ value	θ > 10 (rank : 1407)	NC score	0.051768 (rank : 2113)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1615	Shared Neighborhood Hits	281
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKK1_HUMAN
θ value	θ > 10 (rank : 1408)	NC score	0.056755 (rank : 1951)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1075	Shared Neighborhood Hits	127
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANKK1_MOUSE
θ value	θ > 10 (rank : 1409)	NC score	0.057607 (rank : 1936)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1072	Shared Neighborhood Hits	126
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANPRA_MOUSE
θ value	θ > 10 (rank : 1410)	NC score	0.050042 (rank : 2180)
Query Neighborhood Hits	1371	Target Neighborhood Hits	600	Shared Neighborhood Hits	86
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANR15_HUMAN
θ value	θ > 10 (rank : 1411)	NC score	0.063926 (rank : 1825)
Query Neighborhood Hits	1371	Target Neighborhood Hits	478	Shared Neighborhood Hits	153
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR38_HUMAN
θ value	θ > 10 (rank : 1412)	NC score	0.055516 (rank : 1974)
Query Neighborhood Hits	1371	Target Neighborhood Hits	443	Shared Neighborhood Hits	144
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR38_MOUSE
θ value	θ > 10 (rank : 1413)	NC score	0.078430 (rank : 1655)
Query Neighborhood Hits	1371	Target Neighborhood Hits	512	Shared Neighborhood Hits	200
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

APC_HUMAN
θ value	θ > 10 (rank : 1414)	NC score	0.097795 (rank : 1478)
Query Neighborhood Hits	1371	Target Neighborhood Hits	603	Shared Neighborhood Hits	213
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	θ > 10 (rank : 1415)	NC score	0.083778 (rank : 1601)
Query Neighborhood Hits	1371	Target Neighborhood Hits	441	Shared Neighborhood Hits	170
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APOA1_MOUSE
θ value	θ > 10 (rank : 1416)	NC score	0.178678 (rank : 932)
Query Neighborhood Hits	1371	Target Neighborhood Hits	210	Shared Neighborhood Hits	164
SwissProt Accessions	Q00623	Gene names	Apoa1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I).

APOA4_HUMAN
θ value	θ > 10 (rank : 1417)	NC score	0.268261 (rank : 640)
Query Neighborhood Hits	1371	Target Neighborhood Hits	399	Shared Neighborhood Hits	285
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

APOA4_MOUSE
θ value	θ > 10 (rank : 1418)	NC score	0.271534 (rank : 635)
Query Neighborhood Hits	1371	Target Neighborhood Hits	435	Shared Neighborhood Hits	297
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

APOA5_HUMAN
θ value	θ > 10 (rank : 1419)	NC score	0.050940 (rank : 2148)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	78
SwissProt Accessions	Q6Q788, Q6UWK9, Q9UBJ3	Gene names	APOA5, RAP3
Domain Architecture	No domain graphic available
Description	Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration-associated protein 3).

APOA5_MOUSE
θ value	θ > 10 (rank : 1420)	NC score	0.053729 (rank : 2028)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C7G5, Q91X90, Q99P64	Gene names	Apoa5, Rap3
Domain Architecture	No domain graphic available
Description	Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration-associated protein 3).

APOB_HUMAN
θ value	θ > 10 (rank : 1421)	NC score	0.104255 (rank : 1429)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	121
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

APOE_HUMAN
θ value	θ > 10 (rank : 1422)	NC score	0.132458 (rank : 1214)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	151
SwissProt Accessions	P02649, Q9P2S4	Gene names	APOE
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

APOE_MOUSE
θ value	θ > 10 (rank : 1423)	NC score	0.251151 (rank : 694)
Query Neighborhood Hits	1371	Target Neighborhood Hits	319	Shared Neighborhood Hits	246
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

APS_HUMAN
θ value	θ > 10 (rank : 1424)	NC score	0.084034 (rank : 1595)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_MOUSE
θ value	θ > 10 (rank : 1425)	NC score	0.063248 (rank : 1831)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APXL_HUMAN
θ value	θ > 10 (rank : 1426)	NC score	0.079932 (rank : 1637)
Query Neighborhood Hits	1371	Target Neighborhood Hits	553	Shared Neighborhood Hits	161
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARAF_HUMAN
θ value	θ > 10 (rank : 1427)	NC score	0.056653 (rank : 1955)
Query Neighborhood Hits	1371	Target Neighborhood Hits	924	Shared Neighborhood Hits	111
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	θ > 10 (rank : 1428)	NC score	0.057056 (rank : 1944)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	107
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ATAD3_MOUSE
θ value	θ > 10 (rank : 1429)	NC score	0.158990 (rank : 1044)
Query Neighborhood Hits	1371	Target Neighborhood Hits	326	Shared Neighborhood Hits	228
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

ATD3A_HUMAN
θ value	θ > 10 (rank : 1430)	NC score	0.098757 (rank : 1470)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
θ value	θ > 10 (rank : 1431)	NC score	0.168967 (rank : 988)
Query Neighborhood Hits	1371	Target Neighborhood Hits	340	Shared Neighborhood Hits	245
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATIF1_MOUSE
θ value	θ > 10 (rank : 1432)	NC score	0.056364 (rank : 1961)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	O35143	Gene names	Atpif1, Atpi, If1
Domain Architecture
Description	ATPase inhibitor, mitochondrial precursor.

ATRIP_MOUSE
θ value	θ > 10 (rank : 1433)	NC score	0.134984 (rank : 1191)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	191
SwissProt Accessions	Q8BMG1	Gene names	Atrip
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

ATRX_MOUSE
θ value	θ > 10 (rank : 1434)	NC score	0.091545 (rank : 1529)
Query Neighborhood Hits	1371	Target Neighborhood Hits	682	Shared Neighborhood Hits	256
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATX3_HUMAN
θ value	θ > 10 (rank : 1435)	NC score	0.086696 (rank : 1570)
Query Neighborhood Hits	1371	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	P54252, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0	Gene names	ATXN3, ATX3, MJD, MJD1, SCA3
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein).

BAP31_HUMAN
θ value	θ > 10 (rank : 1436)	NC score	0.138358 (rank : 1173)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	190
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

BAP31_MOUSE
θ value	θ > 10 (rank : 1437)	NC score	0.081601 (rank : 1621)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	101
SwissProt Accessions	Q61335, Q9D0E9, Q9D8G7	Gene names	Bcap31, Bap31
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 1438)	NC score	0.081169 (rank : 1624)
Query Neighborhood Hits	1371	Target Neighborhood Hits	780	Shared Neighborhood Hits	245
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 1439)	NC score	0.051132 (rank : 2141)
Query Neighborhood Hits	1371	Target Neighborhood Hits	744	Shared Neighborhood Hits	183
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 1440)	NC score	0.221976 (rank : 780)
Query Neighborhood Hits	1371	Target Neighborhood Hits	803	Shared Neighborhood Hits	396
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BCAR3_HUMAN
θ value	θ > 10 (rank : 1441)	NC score	0.053279 (rank : 2044)
Query Neighborhood Hits	1371	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BCAR3_MOUSE
θ value	θ > 10 (rank : 1442)	NC score	0.050492 (rank : 2165)
Query Neighborhood Hits	1371	Target Neighborhood Hits	127	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BCAS2_HUMAN
θ value	θ > 10 (rank : 1443)	NC score	0.059907 (rank : 1889)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	66
SwissProt Accessions	O75934, Q6FGS0	Gene names	BCAS2, DAM1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 2 (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27).

BCAS2_MOUSE
θ value	θ > 10 (rank : 1444)	NC score	0.059907 (rank : 1890)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D287, Q3TKJ5, Q91YX8, Q9D2U4, Q9DAI0	Gene names	Bcas2, Dam1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 2 homolog (DNA amplified in mammary carcinoma 1 protein).

BCN1_HUMAN
θ value	θ > 10 (rank : 1445)	NC score	0.257489 (rank : 663)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	326
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

BCN1_MOUSE
θ value	θ > 10 (rank : 1446)	NC score	0.244230 (rank : 717)
Query Neighborhood Hits	1371	Target Neighborhood Hits	367	Shared Neighborhood Hits	299
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

BEGIN_HUMAN
θ value	θ > 10 (rank : 1447)	NC score	0.222305 (rank : 778)
Query Neighborhood Hits	1371	Target Neighborhood Hits	454	Shared Neighborhood Hits	315
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BEGIN_MOUSE
θ value	θ > 10 (rank : 1448)	NC score	0.202720 (rank : 837)
Query Neighborhood Hits	1371	Target Neighborhood Hits	383	Shared Neighborhood Hits	285
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BIN1_HUMAN
θ value	θ > 10 (rank : 1449)	NC score	0.132579 (rank : 1212)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	137
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	θ > 10 (rank : 1450)	NC score	0.133806 (rank : 1202)
Query Neighborhood Hits	1371	Target Neighborhood Hits	283	Shared Neighborhood Hits	139
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BIN3_HUMAN
θ value	θ > 10 (rank : 1451)	NC score	0.089391 (rank : 1545)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQY0, Q9BVG2, Q9NVY9	Gene names	BIN3
Domain Architecture
Description	Bridging integrator 3.

BIN3_MOUSE
θ value	θ > 10 (rank : 1452)	NC score	0.139755 (rank : 1164)
Query Neighborhood Hits	1371	Target Neighborhood Hits	165	Shared Neighborhood Hits	143
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

BLNK_HUMAN
θ value	θ > 10 (rank : 1453)	NC score	0.052255 (rank : 2093)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BLNK_MOUSE
θ value	θ > 10 (rank : 1454)	NC score	0.062166 (rank : 1851)
Query Neighborhood Hits	1371	Target Neighborhood Hits	296	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BMX_HUMAN
θ value	θ > 10 (rank : 1455)	NC score	0.085089 (rank : 1585)
Query Neighborhood Hits	1371	Target Neighborhood Hits	942	Shared Neighborhood Hits	135
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 1456)	NC score	0.084544 (rank : 1588)
Query Neighborhood Hits	1371	Target Neighborhood Hits	912	Shared Neighborhood Hits	130
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BPTF_HUMAN
θ value	θ > 10 (rank : 1457)	NC score	0.095335 (rank : 1493)
Query Neighborhood Hits	1371	Target Neighborhood Hits	786	Shared Neighborhood Hits	228
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRAF1_HUMAN
θ value	θ > 10 (rank : 1458)	NC score	0.058054 (rank : 1923)
Query Neighborhood Hits	1371	Target Neighborhood Hits	883	Shared Neighborhood Hits	111
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BRAP_MOUSE
θ value	θ > 10 (rank : 1459)	NC score	0.190222 (rank : 879)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	247
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRD3_HUMAN
θ value	θ > 10 (rank : 1460)	NC score	0.076937 (rank : 1668)
Query Neighborhood Hits	1371	Target Neighborhood Hits	369	Shared Neighborhood Hits	170
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 1461)	NC score	0.085967 (rank : 1577)
Query Neighborhood Hits	1371	Target Neighborhood Hits	402	Shared Neighborhood Hits	197
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRDT_HUMAN
θ value	θ > 10 (rank : 1462)	NC score	0.065598 (rank : 1805)
Query Neighborhood Hits	1371	Target Neighborhood Hits	280	Shared Neighborhood Hits	135
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BSN_HUMAN
θ value	θ > 10 (rank : 1463)	NC score	0.196678 (rank : 854)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1537	Shared Neighborhood Hits	431
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	θ > 10 (rank : 1464)	NC score	0.178283 (rank : 935)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2057	Shared Neighborhood Hits	477
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BST2_HUMAN
θ value	θ > 10 (rank : 1465)	NC score	0.085860 (rank : 1578)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	64
SwissProt Accessions	Q10589, Q53G07	Gene names	BST2
Domain Architecture
Description	Bone marrow stromal antigen 2 precursor (BST-2) (CD317 antigen) (HM1.24 antigen).

BST2_MOUSE
θ value	θ > 10 (rank : 1466)	NC score	0.054401 (rank : 2004)
Query Neighborhood Hits	1371	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R2Q8, Q8CEY7	Gene names	Bst2
Domain Architecture	No domain graphic available
Description	Bone marrow stromal antigen 2 precursor (BST-2) (CD317 antigen) (HM1.24 antigen).

C8AP2_MOUSE
θ value	θ > 10 (rank : 1467)	NC score	0.063600 (rank : 1828)
Query Neighborhood Hits	1371	Target Neighborhood Hits	405	Shared Neighborhood Hits	153
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CA049_HUMAN
θ value	θ > 10 (rank : 1468)	NC score	0.062780 (rank : 1839)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	56
SwissProt Accessions	Q5T0J7, Q5T0J9, Q8IYU6, Q8N7Z1, Q8NA15, Q9H0Q7	Gene names	C1orf49
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49.

CA049_MOUSE
θ value	θ > 10 (rank : 1469)	NC score	0.085771 (rank : 1580)
Query Neighborhood Hits	1371	Target Neighborhood Hits	121	Shared Neighborhood Hits	93
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

CAR14_HUMAN
θ value	θ > 10 (rank : 1470)	NC score	0.291980 (rank : 581)
Query Neighborhood Hits	1371	Target Neighborhood Hits	449	Shared Neighborhood Hits	345
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CASC5_HUMAN
θ value	θ > 10 (rank : 1471)	NC score	0.197851 (rank : 847)
Query Neighborhood Hits	1371	Target Neighborhood Hits	376	Shared Neighborhood Hits	258
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CCAR1_HUMAN
θ value	θ > 10 (rank : 1472)	NC score	0.195851 (rank : 859)
Query Neighborhood Hits	1371	Target Neighborhood Hits	444	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CCAR1_MOUSE
θ value	θ > 10 (rank : 1473)	NC score	0.183249 (rank : 905)
Query Neighborhood Hits	1371	Target Neighborhood Hits	414	Shared Neighborhood Hits	254
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CCD11_MOUSE
θ value	θ > 10 (rank : 1474)	NC score	0.424759 (rank : 283)
Query Neighborhood Hits	1371	Target Neighborhood Hits	498	Shared Neighborhood Hits	399
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD16_HUMAN
θ value	θ > 10 (rank : 1475)	NC score	0.081301 (rank : 1623)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	116
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

CCD16_MOUSE
θ value	θ > 10 (rank : 1476)	NC score	0.089706 (rank : 1542)
Query Neighborhood Hits	1371	Target Neighborhood Hits	218	Shared Neighborhood Hits	124
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

CCD22_MOUSE
θ value	θ > 10 (rank : 1477)	NC score	0.226826 (rank : 764)
Query Neighborhood Hits	1371	Target Neighborhood Hits	268	Shared Neighborhood Hits	206
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CCD37_MOUSE
θ value	θ > 10 (rank : 1478)	NC score	0.160198 (rank : 1036)
Query Neighborhood Hits	1371	Target Neighborhood Hits	199	Shared Neighborhood Hits	167
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CCD38_MOUSE
θ value	θ > 10 (rank : 1479)	NC score	0.140443 (rank : 1158)
Query Neighborhood Hits	1371	Target Neighborhood Hits	165	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CDN8, Q8CDD6, Q8CDE1	Gene names	Ccdc38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CCD43_HUMAN
θ value	θ > 10 (rank : 1480)	NC score	0.050178 (rank : 2175)
Query Neighborhood Hits	1371	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q96MW1	Gene names	CCDC43
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

CCD50_HUMAN
θ value	θ > 10 (rank : 1481)	NC score	0.161658 (rank : 1027)
Query Neighborhood Hits	1371	Target Neighborhood Hits	237	Shared Neighborhood Hits	181
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CCD50_MOUSE
θ value	θ > 10 (rank : 1482)	NC score	0.117857 (rank : 1316)
Query Neighborhood Hits	1371	Target Neighborhood Hits	172	Shared Neighborhood Hits	137
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CCD55_HUMAN
θ value	θ > 10 (rank : 1483)	NC score	0.146367 (rank : 1122)
Query Neighborhood Hits	1371	Target Neighborhood Hits	513	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD55_MOUSE
θ value	θ > 10 (rank : 1484)	NC score	0.129468 (rank : 1238)
Query Neighborhood Hits	1371	Target Neighborhood Hits	519	Shared Neighborhood Hits	201
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD82_HUMAN
θ value	θ > 10 (rank : 1485)	NC score	0.073904 (rank : 1705)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

CCD94_HUMAN
θ value	θ > 10 (rank : 1486)	NC score	0.114575 (rank : 1348)
Query Neighborhood Hits	1371	Target Neighborhood Hits	139	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BW85, O75270, Q9H862, Q9NW16	Gene names	CCDC94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

CCD94_MOUSE
θ value	θ > 10 (rank : 1487)	NC score	0.116726 (rank : 1325)
Query Neighborhood Hits	1371	Target Neighborhood Hits	127	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D6J3	Gene names	Ccdc94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

CCDC3_HUMAN
θ value	θ > 10 (rank : 1488)	NC score	0.067288 (rank : 1791)
Query Neighborhood Hits	1371	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BQI4	Gene names	CCDC3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

CCDC3_MOUSE
θ value	θ > 10 (rank : 1489)	NC score	0.092598 (rank : 1523)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	103
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

CCDC5_MOUSE
θ value	θ > 10 (rank : 1490)	NC score	0.093721 (rank : 1507)
Query Neighborhood Hits	1371	Target Neighborhood Hits	91	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BHX1, Q3UIH2, Q8R1M1	Gene names	Ccdc5
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5.

CCDC7_HUMAN
θ value	θ > 10 (rank : 1491)	NC score	0.241824 (rank : 722)
Query Neighborhood Hits	1371	Target Neighborhood Hits	253	Shared Neighborhood Hits	201
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

CCNB3_HUMAN
θ value	θ > 10 (rank : 1492)	NC score	0.144802 (rank : 1131)
Query Neighborhood Hits	1371	Target Neighborhood Hits	368	Shared Neighborhood Hits	207
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CD008_HUMAN
θ value	θ > 10 (rank : 1493)	NC score	0.110661 (rank : 1374)
Query Neighborhood Hits	1371	Target Neighborhood Hits	330	Shared Neighborhood Hits	155
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CD016_HUMAN
θ value	θ > 10 (rank : 1494)	NC score	0.053595 (rank : 2034)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	52
SwissProt Accessions	Q63HQ0, Q96GG6, Q9H0V0, Q9P1L4	Gene names	C4orf16
Domain Architecture	No domain graphic available
Description	Protein C4orf16.

CD72_HUMAN
θ value	θ > 10 (rank : 1495)	NC score	0.131368 (rank : 1228)
Query Neighborhood Hits	1371	Target Neighborhood Hits	345	Shared Neighborhood Hits	199
SwissProt Accessions	P21854	Gene names	CD72
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2).

CD72_MOUSE
θ value	θ > 10 (rank : 1496)	NC score	0.136461 (rank : 1185)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	171
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

CDC5L_HUMAN
θ value	θ > 10 (rank : 1497)	NC score	0.079498 (rank : 1643)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	121
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

CDC5L_MOUSE
θ value	θ > 10 (rank : 1498)	NC score	0.085407 (rank : 1583)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	117
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

CE005_HUMAN
θ value	θ > 10 (rank : 1499)	NC score	0.065681 (rank : 1804)
Query Neighborhood Hits	1371	Target Neighborhood Hits	213	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
θ value	θ > 10 (rank : 1500)	NC score	0.060282 (rank : 1877)
Query Neighborhood Hits	1371	Target Neighborhood Hits	238	Shared Neighborhood Hits	119
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE110_HUMAN
θ value	θ > 10 (rank : 1501)	NC score	0.094035 (rank : 1504)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	147
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

CE110_MOUSE
θ value	θ > 10 (rank : 1502)	NC score	0.068449 (rank : 1772)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	108
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

CENPK_MOUSE
θ value	θ > 10 (rank : 1503)	NC score	0.115471 (rank : 1339)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	118
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

CENPQ_MOUSE
θ value	θ > 10 (rank : 1504)	NC score	0.141972 (rank : 1150)
Query Neighborhood Hits	1371	Target Neighborhood Hits	160	Shared Neighborhood Hits	132
SwissProt Accessions	Q9CPQ5, Q8C2G4, Q8VEF8, Q9CX70	Gene names	Cenpq
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

CENPU_HUMAN
θ value	θ > 10 (rank : 1505)	NC score	0.198806 (rank : 846)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	215
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CENPU_MOUSE
θ value	θ > 10 (rank : 1506)	NC score	0.075335 (rank : 1686)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	91
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

CEP55_HUMAN
θ value	θ > 10 (rank : 1507)	NC score	0.405447 (rank : 340)
Query Neighborhood Hits	1371	Target Neighborhood Hits	504	Shared Neighborhood Hits	394
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP72_HUMAN
θ value	θ > 10 (rank : 1508)	NC score	0.147848 (rank : 1109)
Query Neighborhood Hits	1371	Target Neighborhood Hits	374	Shared Neighborhood Hits	202
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CEP72_MOUSE
θ value	θ > 10 (rank : 1509)	NC score	0.192421 (rank : 872)
Query Neighborhood Hits	1371	Target Neighborhood Hits	381	Shared Neighborhood Hits	236
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CF010_HUMAN
θ value	θ > 10 (rank : 1510)	NC score	0.112719 (rank : 1365)
Query Neighborhood Hits	1371	Target Neighborhood Hits	329	Shared Neighborhood Hits	139
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CF118_HUMAN
θ value	θ > 10 (rank : 1511)	NC score	0.134280 (rank : 1195)
Query Neighborhood Hits	1371	Target Neighborhood Hits	154	Shared Neighborhood Hits	120
SwissProt Accessions	Q5T5N4, Q8TC11	Gene names	C6orf118
Domain Architecture	No domain graphic available
Description	Protein C6orf118.

CF153_MOUSE
θ value	θ > 10 (rank : 1512)	NC score	0.071890 (rank : 1732)
Query Neighborhood Hits	1371	Target Neighborhood Hits	78	Shared Neighborhood Hits	51
SwissProt Accessions	Q3UFY0, Q91X71	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153 homolog.

CHCH3_HUMAN
θ value	θ > 10 (rank : 1513)	NC score	0.136487 (rank : 1184)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NX63	Gene names	CHCHD3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CHCH6_MOUSE
θ value	θ > 10 (rank : 1514)	NC score	0.068645 (rank : 1769)
Query Neighborhood Hits	1371	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q91VN4	Gene names	Chchd6
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 6.

CHIN_HUMAN
θ value	θ > 10 (rank : 1515)	NC score	0.092732 (rank : 1520)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	80
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 1516)	NC score	0.094906 (rank : 1498)
Query Neighborhood Hits	1371	Target Neighborhood Hits	229	Shared Neighborhood Hits	83
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 1517)	NC score	0.090887 (rank : 1534)
Query Neighborhood Hits	1371	Target Neighborhood Hits	220	Shared Neighborhood Hits	80
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	θ > 10 (rank : 1518)	NC score	0.067774 (rank : 1782)
Query Neighborhood Hits	1371	Target Neighborhood Hits	130	Shared Neighborhood Hits	42
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHMP5_HUMAN
θ value	θ > 10 (rank : 1519)	NC score	0.073589 (rank : 1708)
Query Neighborhood Hits	1371	Target Neighborhood Hits	103	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZZ3, Q5VXW2, Q96AV2, Q9HB68, Q9NYS4, Q9Y323	Gene names	CHMP5, C9orf83, SNF7DC2
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (Vacuolar protein sorting 60) (Vps60) (hVps60) (SNF7 domain-containing protein 2).

CHMP5_MOUSE
θ value	θ > 10 (rank : 1520)	NC score	0.062494 (rank : 1846)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D7S9, Q3UI64	Gene names	Chmp5, Snf7dc2
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2).

CIP1_HUMAN
θ value	θ > 10 (rank : 1521)	NC score	0.068023 (rank : 1778)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPC3	Gene names	CCNB1IP1, C14orf18, HEI10
Domain Architecture	No domain graphic available
Description	Cyclin-B1-interacting protein 1 (EC 6.3.2.-) (Human enhancer of invasion 10) (E3 ubiquitin-protein ligase HEI10).

CIR_HUMAN
θ value	θ > 10 (rank : 1522)	NC score	0.095273 (rank : 1495)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	116
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CJ049_HUMAN
θ value	θ > 10 (rank : 1523)	NC score	0.074479 (rank : 1698)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

CK035_HUMAN
θ value	θ > 10 (rank : 1524)	NC score	0.058013 (rank : 1925)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IXW0	Gene names	C11orf35
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35.

CKAP4_MOUSE
θ value	θ > 10 (rank : 1525)	NC score	0.394184 (rank : 373)
Query Neighborhood Hits	1371	Target Neighborhood Hits	596	Shared Neighborhood Hits	412
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CL004_HUMAN
θ value	θ > 10 (rank : 1526)	NC score	0.061822 (rank : 1856)
Query Neighborhood Hits	1371	Target Neighborhood Hits	115	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NQ89, Q6MZH5	Gene names	C12orf4
Domain Architecture	No domain graphic available
Description	Protein C12orf4.

CL004_MOUSE
θ value	θ > 10 (rank : 1527)	NC score	0.058616 (rank : 1909)
Query Neighborhood Hits	1371	Target Neighborhood Hits	119	Shared Neighborhood Hits	81
SwissProt Accessions	Q91YN0, Q3UVK4	Gene names	D6Wsu163e
Domain Architecture	No domain graphic available
Description	Protein C12orf4 homolog.

CL025_HUMAN
θ value	θ > 10 (rank : 1528)	NC score	0.105126 (rank : 1425)
Query Neighborhood Hits	1371	Target Neighborhood Hits	179	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

CLC4F_HUMAN
θ value	θ > 10 (rank : 1529)	NC score	0.292529 (rank : 579)
Query Neighborhood Hits	1371	Target Neighborhood Hits	513	Shared Neighborhood Hits	317
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

CLC4F_MOUSE
θ value	θ > 10 (rank : 1530)	NC score	0.249604 (rank : 697)
Query Neighborhood Hits	1371	Target Neighborhood Hits	572	Shared Neighborhood Hits	334
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

CLC4M_HUMAN
θ value	θ > 10 (rank : 1531)	NC score	0.052168 (rank : 2096)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	120
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

CLCA_MOUSE
θ value	θ > 10 (rank : 1532)	NC score	0.057893 (rank : 1930)
Query Neighborhood Hits	1371	Target Neighborhood Hits	106	Shared Neighborhood Hits	84
SwissProt Accessions	O08585	Gene names	Clta
Domain Architecture
Description	Clathrin light chain A (Lca).

CLSPN_HUMAN
θ value	θ > 10 (rank : 1533)	NC score	0.140039 (rank : 1161)
Query Neighborhood Hits	1371	Target Neighborhood Hits	433	Shared Neighborhood Hits	244
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CLSPN_MOUSE
θ value	θ > 10 (rank : 1534)	NC score	0.053164 (rank : 2050)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	113
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

CLUA1_HUMAN
θ value	θ > 10 (rank : 1535)	NC score	0.187278 (rank : 887)
Query Neighborhood Hits	1371	Target Neighborhood Hits	236	Shared Neighborhood Hits	190
SwissProt Accessions	Q96AJ1, O75138, Q65ZA3, Q9H8R4, Q9H8T1	Gene names	CLUAP1, KIAA0643
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

CLUA1_MOUSE
θ value	θ > 10 (rank : 1536)	NC score	0.212236 (rank : 812)
Query Neighborhood Hits	1371	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

CMGA_HUMAN
θ value	θ > 10 (rank : 1537)	NC score	0.052238 (rank : 2094)
Query Neighborhood Hits	1371	Target Neighborhood Hits	238	Shared Neighborhood Hits	86
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

CN044_HUMAN
θ value	θ > 10 (rank : 1538)	NC score	0.121293 (rank : 1291)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	161
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

CN045_HUMAN
θ value	θ > 10 (rank : 1539)	NC score	0.210161 (rank : 820)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	183
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

CNOT3_HUMAN
θ value	θ > 10 (rank : 1540)	NC score	0.101320 (rank : 1452)
Query Neighborhood Hits	1371	Target Neighborhood Hits	425	Shared Neighborhood Hits	164
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 1541)	NC score	0.109456 (rank : 1383)
Query Neighborhood Hits	1371	Target Neighborhood Hits	504	Shared Neighborhood Hits	186
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

COG6_HUMAN
θ value	θ > 10 (rank : 1542)	NC score	0.067689 (rank : 1784)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y2V7, Q5T0U1, Q9ULT5	Gene names	COG6, KIAA1134
Domain Architecture
Description	Conserved oligomeric Golgi complex component 6.

COG7_HUMAN
θ value	θ > 10 (rank : 1543)	NC score	0.061876 (rank : 1855)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	80
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

COVA1_MOUSE
θ value	θ > 10 (rank : 1544)	NC score	0.239648 (rank : 728)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	228
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

CP045_HUMAN
θ value	θ > 10 (rank : 1545)	NC score	0.058791 (rank : 1903)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	58
SwissProt Accessions	Q96MC5, O00223, O75769, Q8IZ36, Q96H25	Gene names	C16orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf45.

CP045_MOUSE
θ value	θ > 10 (rank : 1546)	NC score	0.063483 (rank : 1830)
Query Neighborhood Hits	1371	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R1Y2, Q3UVX0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf45 homolog.

CPLX2_HUMAN
θ value	θ > 10 (rank : 1547)	NC score	0.061138 (rank : 1862)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PUV4, O09056, Q13329, Q28184, Q52M15, Q64386	Gene names	CPLX2
Domain Architecture	No domain graphic available
Description	Complexin-2 (Complexin II) (CPX II) (Synaphin-1).

CPLX2_MOUSE
θ value	θ > 10 (rank : 1548)	NC score	0.061138 (rank : 1863)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	76
SwissProt Accessions	P84086, O09056, Q13329, Q28184, Q32KK4, Q64386	Gene names	Cplx2
Domain Architecture	No domain graphic available
Description	Complexin-2 (Complexin II) (CPX II) (Synaphin-1) (921-L).

CS029_MOUSE
θ value	θ > 10 (rank : 1549)	NC score	0.107631 (rank : 1399)
Query Neighborhood Hits	1371	Target Neighborhood Hits	201	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

CSF1R_HUMAN
θ value	θ > 10 (rank : 1550)	NC score	0.050746 (rank : 2156)
Query Neighborhood Hits	1371	Target Neighborhood Hits	943	Shared Neighborhood Hits	93
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CT077_HUMAN
θ value	θ > 10 (rank : 1551)	NC score	0.102503 (rank : 1439)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

CT077_MOUSE
θ value	θ > 10 (rank : 1552)	NC score	0.101075 (rank : 1455)
Query Neighborhood Hits	1371	Target Neighborhood Hits	122	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CSU0, Q3U8H1, Q3UGH1, Q3USX3, Q6GTJ6	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf77 homolog.

CT116_HUMAN
θ value	θ > 10 (rank : 1553)	NC score	0.237614 (rank : 733)
Query Neighborhood Hits	1371	Target Neighborhood Hits	294	Shared Neighborhood Hits	232
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

CT116_MOUSE
θ value	θ > 10 (rank : 1554)	NC score	0.212350 (rank : 811)
Query Neighborhood Hits	1371	Target Neighborhood Hits	268	Shared Neighborhood Hits	200
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

CT151_HUMAN
θ value	θ > 10 (rank : 1555)	NC score	0.139645 (rank : 1166)
Query Neighborhood Hits	1371	Target Neighborhood Hits	382	Shared Neighborhood Hits	170
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CTGE2_HUMAN
θ value	θ > 10 (rank : 1556)	NC score	0.347079 (rank : 474)
Query Neighborhood Hits	1371	Target Neighborhood Hits	594	Shared Neighborhood Hits	421
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

CTGE3_HUMAN
θ value	θ > 10 (rank : 1557)	NC score	0.087543 (rank : 1561)
Query Neighborhood Hits	1371	Target Neighborhood Hits	77	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IX95	Gene names	CTAGE3
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 3 (cTAGE-3 protein).

CTNL1_HUMAN
θ value	θ > 10 (rank : 1558)	NC score	0.052767 (rank : 2065)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UBT7, O76084, Q53FQ2, Q5JTQ7, Q5JTQ8, Q9Y401	Gene names	CTNNAL1
Domain Architecture	No domain graphic available
Description	Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) (ACRP).

CTR9_HUMAN
θ value	θ > 10 (rank : 1559)	NC score	0.076373 (rank : 1672)
Query Neighborhood Hits	1371	Target Neighborhood Hits	383	Shared Neighborhood Hits	160
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CTR9_MOUSE
θ value	θ > 10 (rank : 1560)	NC score	0.077615 (rank : 1659)
Query Neighborhood Hits	1371	Target Neighborhood Hits	427	Shared Neighborhood Hits	174
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

CUTL2_HUMAN
θ value	θ > 10 (rank : 1561)	NC score	0.236075 (rank : 736)
Query Neighborhood Hits	1371	Target Neighborhood Hits	906	Shared Neighborhood Hits	356
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CUTL2_MOUSE
θ value	θ > 10 (rank : 1562)	NC score	0.209739 (rank : 823)
Query Neighborhood Hits	1371	Target Neighborhood Hits	771	Shared Neighborhood Hits	313
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CYLC1_HUMAN
θ value	θ > 10 (rank : 1563)	NC score	0.148106 (rank : 1107)
Query Neighborhood Hits	1371	Target Neighborhood Hits	408	Shared Neighborhood Hits	170
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CYLC2_HUMAN
θ value	θ > 10 (rank : 1564)	NC score	0.066687 (rank : 1797)
Query Neighborhood Hits	1371	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DAAM2_MOUSE
θ value	θ > 10 (rank : 1565)	NC score	0.095788 (rank : 1490)
Query Neighborhood Hits	1371	Target Neighborhood Hits	371	Shared Neighborhood Hits	225
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DAB2P_HUMAN
θ value	θ > 10 (rank : 1566)	NC score	0.089484 (rank : 1544)
Query Neighborhood Hits	1371	Target Neighborhood Hits	303	Shared Neighborhood Hits	178
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	θ > 10 (rank : 1567)	NC score	0.092635 (rank : 1522)
Query Neighborhood Hits	1371	Target Neighborhood Hits	284	Shared Neighborhood Hits	177
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

DACH2_HUMAN
θ value	θ > 10 (rank : 1568)	NC score	0.059489 (rank : 1893)
Query Neighborhood Hits	1371	Target Neighborhood Hits	122	Shared Neighborhood Hits	100
SwissProt Accessions	Q96NX9, Q8NAY3, Q8ND17, Q96N55	Gene names	DACH2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

DACH2_MOUSE
θ value	θ > 10 (rank : 1569)	NC score	0.058435 (rank : 1913)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	98
SwissProt Accessions	Q925Q8, Q8BMA0	Gene names	Dach2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

DAPP1_HUMAN
θ value	θ > 10 (rank : 1570)	NC score	0.121652 (rank : 1288)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 1571)	NC score	0.122057 (rank : 1285)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDIT3_HUMAN
θ value	θ > 10 (rank : 1572)	NC score	0.069859 (rank : 1755)
Query Neighborhood Hits	1371	Target Neighborhood Hits	167	Shared Neighborhood Hits	102
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

DDR1_HUMAN
θ value	θ > 10 (rank : 1573)	NC score	0.056465 (rank : 1959)
Query Neighborhood Hits	1371	Target Neighborhood Hits	819	Shared Neighborhood Hits	93
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 1574)	NC score	0.056142 (rank : 1963)
Query Neighborhood Hits	1371	Target Neighborhood Hits	818	Shared Neighborhood Hits	93
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 1575)	NC score	0.055062 (rank : 1984)
Query Neighborhood Hits	1371	Target Neighborhood Hits	818	Shared Neighborhood Hits	97
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 1576)	NC score	0.053914 (rank : 2024)
Query Neighborhood Hits	1371	Target Neighborhood Hits	813	Shared Neighborhood Hits	95
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDX11_HUMAN
θ value	θ > 10 (rank : 1577)	NC score	0.052739 (rank : 2068)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	93
SwissProt Accessions	Q96FC9, Q13333, Q86VQ4, Q86W62, Q92498, Q92770, Q92998, Q92999	Gene names	DDX11, CHL1, CHLR1, KRG2
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11) (CHL1 homolog) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2).

DEK_MOUSE
θ value	θ > 10 (rank : 1578)	NC score	0.069810 (rank : 1756)
Query Neighborhood Hits	1371	Target Neighborhood Hits	280	Shared Neighborhood Hits	102
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DESM_HUMAN
θ value	θ > 10 (rank : 1579)	NC score	0.185367 (rank : 898)
Query Neighborhood Hits	1371	Target Neighborhood Hits	495	Shared Neighborhood Hits	370
SwissProt Accessions	P17661, Q15787, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80	Gene names	DES
Domain Architecture
Description	Desmin.

DESM_MOUSE
θ value	θ > 10 (rank : 1580)	NC score	0.186506 (rank : 894)
Query Neighborhood Hits	1371	Target Neighborhood Hits	498	Shared Neighborhood Hits	374
SwissProt Accessions	P31001	Gene names	Des
Domain Architecture
Description	Desmin.

DFFA_HUMAN
θ value	θ > 10 (rank : 1581)	NC score	0.079909 (rank : 1638)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	80
SwissProt Accessions	O00273, Q96I97, Q9Y6C6	Gene names	DFFA, DFF1, DFF45
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

DFFA_MOUSE
θ value	θ > 10 (rank : 1582)	NC score	0.055116 (rank : 1981)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	O54786, O54787	Gene names	Dffa, Icad
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

DHX16_HUMAN
θ value	θ > 10 (rank : 1583)	NC score	0.096837 (rank : 1482)
Query Neighborhood Hits	1371	Target Neighborhood Hits	356	Shared Neighborhood Hits	233
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DIAP1_HUMAN
θ value	θ > 10 (rank : 1584)	NC score	0.184747 (rank : 902)
Query Neighborhood Hits	1371	Target Neighborhood Hits	784	Shared Neighborhood Hits	378
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP2_HUMAN
θ value	θ > 10 (rank : 1585)	NC score	0.075174 (rank : 1688)
Query Neighborhood Hits	1371	Target Neighborhood Hits	342	Shared Neighborhood Hits	177
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DISC1_HUMAN
θ value	θ > 10 (rank : 1586)	NC score	0.152554 (rank : 1082)
Query Neighborhood Hits	1371	Target Neighborhood Hits	199	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NRI5, O75045, Q5VT44, Q5VT45, Q8IXJ0, Q8IXJ1, Q9BX19, Q9NRI3, Q9NRI4	Gene names	DISC1, KIAA0457
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 protein.

DJC17_HUMAN
θ value	θ > 10 (rank : 1587)	NC score	0.131166 (rank : 1230)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	231
SwissProt Accessions	Q9NVM6	Gene names	DNAJC17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

DJC17_MOUSE
θ value	θ > 10 (rank : 1588)	NC score	0.058923 (rank : 1901)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	121
SwissProt Accessions	Q91WT4, Q8C5R1	Gene names	Dnajc17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

DLG4_HUMAN
θ value	θ > 10 (rank : 1589)	NC score	0.070734 (rank : 1744)
Query Neighborhood Hits	1371	Target Neighborhood Hits	286	Shared Neighborhood Hits	110
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	θ > 10 (rank : 1590)	NC score	0.068274 (rank : 1774)
Query Neighborhood Hits	1371	Target Neighborhood Hits	282	Shared Neighborhood Hits	106
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DMP1_MOUSE
θ value	θ > 10 (rank : 1591)	NC score	0.052942 (rank : 2061)
Query Neighborhood Hits	1371	Target Neighborhood Hits	498	Shared Neighborhood Hits	105
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DMPK_HUMAN
θ value	θ > 10 (rank : 1592)	NC score	0.060592 (rank : 1872)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	172
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

DOT1L_HUMAN
θ value	θ > 10 (rank : 1593)	NC score	0.127353 (rank : 1258)
Query Neighborhood Hits	1371	Target Neighborhood Hits	660	Shared Neighborhood Hits	182
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DRP2_HUMAN
θ value	θ > 10 (rank : 1594)	NC score	0.093530 (rank : 1510)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	127
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

DTBP1_HUMAN
θ value	θ > 10 (rank : 1595)	NC score	0.124889 (rank : 1269)
Query Neighborhood Hits	1371	Target Neighborhood Hits	185	Shared Neighborhood Hits	143
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

DTBP1_MOUSE
θ value	θ > 10 (rank : 1596)	NC score	0.147714 (rank : 1110)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	165
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

DTNA_HUMAN
θ value	θ > 10 (rank : 1597)	NC score	0.114496 (rank : 1350)
Query Neighborhood Hits	1371	Target Neighborhood Hits	295	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

DTNA_MOUSE
θ value	θ > 10 (rank : 1598)	NC score	0.105403 (rank : 1422)
Query Neighborhood Hits	1371	Target Neighborhood Hits	264	Shared Neighborhood Hits	184
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

DTNB_HUMAN
θ value	θ > 10 (rank : 1599)	NC score	0.106899 (rank : 1411)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	188
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

DYDC1_HUMAN
θ value	θ > 10 (rank : 1600)	NC score	0.121656 (rank : 1287)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	114
SwissProt Accessions	Q8WWB3, Q5QP03, Q5QP04, Q6WNP4, Q6ZU87	Gene names	DYDC1, DPY30D1
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 1 (RSD-9).

DYH11_HUMAN
θ value	θ > 10 (rank : 1601)	NC score	0.068547 (rank : 1770)
Query Neighborhood Hits	1371	Target Neighborhood Hits	234	Shared Neighborhood Hits	151
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

DYH5_HUMAN
θ value	θ > 10 (rank : 1602)	NC score	0.090706 (rank : 1535)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	207
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

DYH5_MOUSE
θ value	θ > 10 (rank : 1603)	NC score	0.087771 (rank : 1559)
Query Neighborhood Hits	1371	Target Neighborhood Hits	286	Shared Neighborhood Hits	185
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

DYH9_HUMAN
θ value	θ > 10 (rank : 1604)	NC score	0.069971 (rank : 1754)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

DZIP1_HUMAN
θ value	θ > 10 (rank : 1605)	NC score	0.216054 (rank : 800)
Query Neighborhood Hits	1371	Target Neighborhood Hits	675	Shared Neighborhood Hits	256
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

DZIP3_HUMAN
θ value	θ > 10 (rank : 1606)	NC score	0.161239 (rank : 1030)
Query Neighborhood Hits	1371	Target Neighborhood Hits	399	Shared Neighborhood Hits	227
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	θ > 10 (rank : 1607)	NC score	0.156070 (rank : 1068)
Query Neighborhood Hits	1371	Target Neighborhood Hits	414	Shared Neighborhood Hits	223
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

E2AK4_HUMAN
θ value	θ > 10 (rank : 1608)	NC score	0.054600 (rank : 1996)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1012	Shared Neighborhood Hits	193
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

E2AK4_MOUSE
θ value	θ > 10 (rank : 1609)	NC score	0.051444 (rank : 2124)
Query Neighborhood Hits	1371	Target Neighborhood Hits	984	Shared Neighborhood Hits	162
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

E41L2_HUMAN
θ value	θ > 10 (rank : 1610)	NC score	0.067106 (rank : 1792)
Query Neighborhood Hits	1371	Target Neighborhood Hits	287	Shared Neighborhood Hits	150
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

EGFR_HUMAN
θ value	θ > 10 (rank : 1611)	NC score	0.053729 (rank : 2029)
Query Neighborhood Hits	1371	Target Neighborhood Hits	939	Shared Neighborhood Hits	101
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 1612)	NC score	0.053611 (rank : 2032)
Query Neighborhood Hits	1371	Target Neighborhood Hits	927	Shared Neighborhood Hits	98
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EMIL2_HUMAN
θ value	θ > 10 (rank : 1613)	NC score	0.182375 (rank : 909)
Query Neighborhood Hits	1371	Target Neighborhood Hits	573	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

EMIL2_MOUSE
θ value	θ > 10 (rank : 1614)	NC score	0.127724 (rank : 1254)
Query Neighborhood Hits	1371	Target Neighborhood Hits	485	Shared Neighborhood Hits	200
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

EMIL3_HUMAN
θ value	θ > 10 (rank : 1615)	NC score	0.119852 (rank : 1306)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

EMIL3_MOUSE
θ value	θ > 10 (rank : 1616)	NC score	0.131051 (rank : 1231)
Query Neighborhood Hits	1371	Target Neighborhood Hits	240	Shared Neighborhood Hits	167
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

EPHA1_HUMAN
θ value	θ > 10 (rank : 1617)	NC score	0.053691 (rank : 2030)
Query Neighborhood Hits	1371	Target Neighborhood Hits	997	Shared Neighborhood Hits	104
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA1_MOUSE
θ value	θ > 10 (rank : 1618)	NC score	0.054120 (rank : 2015)
Query Neighborhood Hits	1371	Target Neighborhood Hits	958	Shared Neighborhood Hits	101
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA2_HUMAN
θ value	θ > 10 (rank : 1619)	NC score	0.051444 (rank : 2123)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1021	Shared Neighborhood Hits	109
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA2_MOUSE
θ value	θ > 10 (rank : 1620)	NC score	0.051581 (rank : 2117)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1020	Shared Neighborhood Hits	107
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA3_HUMAN
θ value	θ > 10 (rank : 1621)	NC score	0.051046 (rank : 2145)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1005	Shared Neighborhood Hits	99
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA3_MOUSE
θ value	θ > 10 (rank : 1622)	NC score	0.050834 (rank : 2152)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	100
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA4_HUMAN
θ value	θ > 10 (rank : 1623)	NC score	0.051421 (rank : 2128)
Query Neighborhood Hits	1371	Target Neighborhood Hits	975	Shared Neighborhood Hits	104
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	θ > 10 (rank : 1624)	NC score	0.051412 (rank : 2129)
Query Neighborhood Hits	1371	Target Neighborhood Hits	982	Shared Neighborhood Hits	105
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA5_HUMAN
θ value	θ > 10 (rank : 1625)	NC score	0.051327 (rank : 2131)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	104
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA5_MOUSE
θ value	θ > 10 (rank : 1626)	NC score	0.053326 (rank : 2042)
Query Neighborhood Hits	1371	Target Neighborhood Hits	950	Shared Neighborhood Hits	100
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA6_HUMAN
θ value	θ > 10 (rank : 1627)	NC score	0.052598 (rank : 2073)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
θ value	θ > 10 (rank : 1628)	NC score	0.052556 (rank : 2077)
Query Neighborhood Hits	1371	Target Neighborhood Hits	946	Shared Neighborhood Hits	102
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA7_HUMAN
θ value	θ > 10 (rank : 1629)	NC score	0.050733 (rank : 2159)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1053	Shared Neighborhood Hits	105
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
θ value	θ > 10 (rank : 1630)	NC score	0.050973 (rank : 2147)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1025	Shared Neighborhood Hits	105
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHA8_HUMAN
θ value	θ > 10 (rank : 1631)	NC score	0.051672 (rank : 2115)
Query Neighborhood Hits	1371	Target Neighborhood Hits	956	Shared Neighborhood Hits	99
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	θ > 10 (rank : 1632)	NC score	0.052058 (rank : 2099)
Query Neighborhood Hits	1371	Target Neighborhood Hits	969	Shared Neighborhood Hits	100
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

EPHAA_HUMAN
θ value	θ > 10 (rank : 1633)	NC score	0.054314 (rank : 2008)
Query Neighborhood Hits	1371	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB1_HUMAN
θ value	θ > 10 (rank : 1634)	NC score	0.052045 (rank : 2101)
Query Neighborhood Hits	1371	Target Neighborhood Hits	988	Shared Neighborhood Hits	105
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB2_HUMAN
θ value	θ > 10 (rank : 1635)	NC score	0.051483 (rank : 2122)
Query Neighborhood Hits	1371	Target Neighborhood Hits	983	Shared Neighborhood Hits	102
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	θ > 10 (rank : 1636)	NC score	0.051428 (rank : 2127)
Query Neighborhood Hits	1371	Target Neighborhood Hits	982	Shared Neighborhood Hits	102
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB3_HUMAN
θ value	θ > 10 (rank : 1637)	NC score	0.051552 (rank : 2118)
Query Neighborhood Hits	1371	Target Neighborhood Hits	996	Shared Neighborhood Hits	111
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
θ value	θ > 10 (rank : 1638)	NC score	0.051279 (rank : 2134)
Query Neighborhood Hits	1371	Target Neighborhood Hits	996	Shared Neighborhood Hits	110
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB4_HUMAN
θ value	θ > 10 (rank : 1639)	NC score	0.051308 (rank : 2132)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1056	Shared Neighborhood Hits	103
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	θ > 10 (rank : 1640)	NC score	0.051029 (rank : 2146)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1013	Shared Neighborhood Hits	104
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHB6_MOUSE
θ value	θ > 10 (rank : 1641)	NC score	0.051540 (rank : 2119)
Query Neighborhood Hits	1371	Target Neighborhood Hits	906	Shared Neighborhood Hits	97
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

ERBB2_HUMAN
θ value	θ > 10 (rank : 1642)	NC score	0.054673 (rank : 1995)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1073	Shared Neighborhood Hits	114
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 1643)	NC score	0.054421 (rank : 2001)
Query Neighborhood Hits	1371	Target Neighborhood Hits	918	Shared Neighborhood Hits	101
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 1644)	NC score	0.054278 (rank : 2011)
Query Neighborhood Hits	1371	Target Neighborhood Hits	918	Shared Neighborhood Hits	93
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 1645)	NC score	0.054692 (rank : 1993)
Query Neighborhood Hits	1371	Target Neighborhood Hits	898	Shared Neighborhood Hits	93
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 1646)	NC score	0.055765 (rank : 1971)
Query Neighborhood Hits	1371	Target Neighborhood Hits	910	Shared Neighborhood Hits	100
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

EVC_HUMAN
θ value	θ > 10 (rank : 1647)	NC score	0.081030 (rank : 1626)
Query Neighborhood Hits	1371	Target Neighborhood Hits	129	Shared Neighborhood Hits	92
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

F107B_HUMAN
θ value	θ > 10 (rank : 1648)	NC score	0.147222 (rank : 1114)
Query Neighborhood Hits	1371	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

F107B_MOUSE
θ value	θ > 10 (rank : 1649)	NC score	0.146197 (rank : 1123)
Query Neighborhood Hits	1371	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

FA44A_HUMAN
θ value	θ > 10 (rank : 1650)	NC score	0.076341 (rank : 1673)
Query Neighborhood Hits	1371	Target Neighborhood Hits	280	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

FA50A_HUMAN
θ value	θ > 10 (rank : 1651)	NC score	0.203869 (rank : 835)
Query Neighborhood Hits	1371	Target Neighborhood Hits	264	Shared Neighborhood Hits	224
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

FA50A_MOUSE
θ value	θ > 10 (rank : 1652)	NC score	0.229981 (rank : 753)
Query Neighborhood Hits	1371	Target Neighborhood Hits	293	Shared Neighborhood Hits	251
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

FA50B_HUMAN
θ value	θ > 10 (rank : 1653)	NC score	0.096367 (rank : 1485)
Query Neighborhood Hits	1371	Target Neighborhood Hits	130	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y247	Gene names	FAM50B, X5L
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

FA50B_MOUSE
θ value	θ > 10 (rank : 1654)	NC score	0.111423 (rank : 1371)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	149
SwissProt Accessions	Q9WTJ8, Q80X84, Q9D993	Gene names	Fam50b, D0H6S2654E, X5l
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

FA76A_HUMAN
θ value	θ > 10 (rank : 1655)	NC score	0.059853 (rank : 1891)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TAV0, O95565, O95566, Q8N7J5	Gene names	FAM76A
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

FA76A_MOUSE
θ value	θ > 10 (rank : 1656)	NC score	0.055394 (rank : 1975)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	100
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

FA76B_HUMAN
θ value	θ > 10 (rank : 1657)	NC score	0.079990 (rank : 1636)
Query Neighborhood Hits	1371	Target Neighborhood Hits	184	Shared Neighborhood Hits	130
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FA76B_MOUSE
θ value	θ > 10 (rank : 1658)	NC score	0.077665 (rank : 1658)
Query Neighborhood Hits	1371	Target Neighborhood Hits	181	Shared Neighborhood Hits	129
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FAK1_HUMAN
θ value	θ > 10 (rank : 1659)	NC score	0.057034 (rank : 1945)
Query Neighborhood Hits	1371	Target Neighborhood Hits	850	Shared Neighborhood Hits	101
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 1660)	NC score	0.056587 (rank : 1957)
Query Neighborhood Hits	1371	Target Neighborhood Hits	850	Shared Neighborhood Hits	97
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 1661)	NC score	0.060148 (rank : 1882)
Query Neighborhood Hits	1371	Target Neighborhood Hits	847	Shared Neighborhood Hits	110
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAM9A_HUMAN
θ value	θ > 10 (rank : 1662)	NC score	0.052700 (rank : 2071)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

FAM9B_HUMAN
θ value	θ > 10 (rank : 1663)	NC score	0.060219 (rank : 1879)
Query Neighborhood Hits	1371	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZU0	Gene names	FAM9B
Domain Architecture	No domain graphic available
Description	Protein FAM9B.

FBX28_HUMAN
θ value	θ > 10 (rank : 1664)	NC score	0.092645 (rank : 1521)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NVF7, O75070	Gene names	FBXO28, KIAA0483
Domain Architecture	No domain graphic available
Description	F-box only protein 28.

FBX41_HUMAN
θ value	θ > 10 (rank : 1665)	NC score	0.197428 (rank : 848)
Query Neighborhood Hits	1371	Target Neighborhood Hits	475	Shared Neighborhood Hits	273
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	θ > 10 (rank : 1666)	NC score	0.200480 (rank : 843)
Query Neighborhood Hits	1371	Target Neighborhood Hits	430	Shared Neighborhood Hits	269
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FCER2_MOUSE
θ value	θ > 10 (rank : 1667)	NC score	0.080275 (rank : 1631)
Query Neighborhood Hits	1371	Target Neighborhood Hits	392	Shared Neighborhood Hits	215
SwissProt Accessions	P20693, Q61556, Q61557	Gene names	Fcer2, Fcer2a
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IGE receptor) (Fc-epsilon-RII) (CD23 antigen).

FES_HUMAN
θ value	θ > 10 (rank : 1668)	NC score	0.074910 (rank : 1691)
Query Neighborhood Hits	1371	Target Neighborhood Hits	978	Shared Neighborhood Hits	194
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FEZ1_HUMAN
θ value	θ > 10 (rank : 1669)	NC score	0.060229 (rank : 1878)
Query Neighborhood Hits	1371	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	Q99689, O00679, O00728, Q6IBI7	Gene names	FEZ1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

FEZ2_MOUSE
θ value	θ > 10 (rank : 1670)	NC score	0.067290 (rank : 1790)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

FGFR2_MOUSE
θ value	θ > 10 (rank : 1671)	NC score	0.050049 (rank : 2179)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1062	Shared Neighborhood Hits	97
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FLOT1_HUMAN
θ value	θ > 10 (rank : 1672)	NC score	0.096646 (rank : 1484)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	113
SwissProt Accessions	O75955, Q969J8, Q9UHW1, Q9UNV8	Gene names	FLOT1
Domain Architecture
Description	Flotillin-1.

FLOT1_MOUSE
θ value	θ > 10 (rank : 1673)	NC score	0.083819 (rank : 1599)
Query Neighborhood Hits	1371	Target Neighborhood Hits	128	Shared Neighborhood Hits	93
SwissProt Accessions	O08917	Gene names	Flot1
Domain Architecture
Description	Flotillin-1.

FLT3_HUMAN
θ value	θ > 10 (rank : 1674)	NC score	0.051815 (rank : 2110)
Query Neighborhood Hits	1371	Target Neighborhood Hits	843	Shared Neighborhood Hits	96
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 1675)	NC score	0.051504 (rank : 2120)
Query Neighborhood Hits	1371	Target Neighborhood Hits	847	Shared Neighborhood Hits	92
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FMNL_HUMAN
θ value	θ > 10 (rank : 1676)	NC score	0.086180 (rank : 1573)
Query Neighborhood Hits	1371	Target Neighborhood Hits	529	Shared Neighborhood Hits	192
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FMNL_MOUSE
θ value	θ > 10 (rank : 1677)	NC score	0.087427 (rank : 1563)
Query Neighborhood Hits	1371	Target Neighborhood Hits	428	Shared Neighborhood Hits	184
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FOXP2_HUMAN
θ value	θ > 10 (rank : 1678)	NC score	0.102171 (rank : 1444)
Query Neighborhood Hits	1371	Target Neighborhood Hits	366	Shared Neighborhood Hits	216
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

FUT8_HUMAN
θ value	θ > 10 (rank : 1679)	NC score	0.066541 (rank : 1799)
Query Neighborhood Hits	1371	Target Neighborhood Hits	67	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYC5, O00235, Q9BYC6, Q9P2U5, Q9P2U6	Gene names	FUT8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

FUT8_MOUSE
θ value	θ > 10 (rank : 1680)	NC score	0.097950 (rank : 1476)
Query Neighborhood Hits	1371	Target Neighborhood Hits	115	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

FYB_HUMAN
θ value	θ > 10 (rank : 1681)	NC score	0.051657 (rank : 2116)
Query Neighborhood Hits	1371	Target Neighborhood Hits	379	Shared Neighborhood Hits	101
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

FYV1_HUMAN
θ value	θ > 10 (rank : 1682)	NC score	0.059281 (rank : 1897)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	θ > 10 (rank : 1683)	NC score	0.058689 (rank : 1906)
Query Neighborhood Hits	1371	Target Neighborhood Hits	191	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

G45IP_MOUSE
θ value	θ > 10 (rank : 1684)	NC score	0.114930 (rank : 1344)
Query Neighborhood Hits	1371	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

GAS7_HUMAN
θ value	θ > 10 (rank : 1685)	NC score	0.165329 (rank : 1008)
Query Neighborhood Hits	1371	Target Neighborhood Hits	258	Shared Neighborhood Hits	185
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
θ value	θ > 10 (rank : 1686)	NC score	0.156353 (rank : 1062)
Query Neighborhood Hits	1371	Target Neighborhood Hits	259	Shared Neighborhood Hits	180
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GBP1_HUMAN
θ value	θ > 10 (rank : 1687)	NC score	0.156141 (rank : 1066)
Query Neighborhood Hits	1371	Target Neighborhood Hits	339	Shared Neighborhood Hits	264
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

GBP1_MOUSE
θ value	θ > 10 (rank : 1688)	NC score	0.131858 (rank : 1222)
Query Neighborhood Hits	1371	Target Neighborhood Hits	302	Shared Neighborhood Hits	225
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

GBP2_HUMAN
θ value	θ > 10 (rank : 1689)	NC score	0.161600 (rank : 1028)
Query Neighborhood Hits	1371	Target Neighborhood Hits	349	Shared Neighborhood Hits	268
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

GBP2_MOUSE
θ value	θ > 10 (rank : 1690)	NC score	0.143742 (rank : 1138)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

GBP5_HUMAN
θ value	θ > 10 (rank : 1691)	NC score	0.090605 (rank : 1536)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	152
SwissProt Accessions	Q96PP8	Gene names	GBP5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (GBP-TA antigen).

GBP5_MOUSE
θ value	θ > 10 (rank : 1692)	NC score	0.113442 (rank : 1362)
Query Neighborhood Hits	1371	Target Neighborhood Hits	254	Shared Neighborhood Hits	199
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

GCF_HUMAN
θ value	θ > 10 (rank : 1693)	NC score	0.069993 (rank : 1753)
Query Neighborhood Hits	1371	Target Neighborhood Hits	107	Shared Neighborhood Hits	76
SwissProt Accessions	P16383, O95032	Gene names	TCF9, C2orf3
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9).

GCP60_MOUSE
θ value	θ > 10 (rank : 1694)	NC score	0.241394 (rank : 723)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	295
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GEMI_HUMAN
θ value	θ > 10 (rank : 1695)	NC score	0.092424 (rank : 1524)
Query Neighborhood Hits	1371	Target Neighborhood Hits	192	Shared Neighborhood Hits	134
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

GEMI_MOUSE
θ value	θ > 10 (rank : 1696)	NC score	0.092789 (rank : 1517)
Query Neighborhood Hits	1371	Target Neighborhood Hits	163	Shared Neighborhood Hits	124
SwissProt Accessions	O88513	Gene names	Gmnn
Domain Architecture
Description	Geminin.

GLU2B_HUMAN
θ value	θ > 10 (rank : 1697)	NC score	0.115722 (rank : 1334)
Query Neighborhood Hits	1371	Target Neighborhood Hits	377	Shared Neighborhood Hits	181
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
θ value	θ > 10 (rank : 1698)	NC score	0.116616 (rank : 1328)
Query Neighborhood Hits	1371	Target Neighborhood Hits	357	Shared Neighborhood Hits	183
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GMIP_MOUSE
θ value	θ > 10 (rank : 1699)	NC score	0.052332 (rank : 2087)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	87
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GO45_HUMAN
θ value	θ > 10 (rank : 1700)	NC score	0.174650 (rank : 955)
Query Neighborhood Hits	1371	Target Neighborhood Hits	189	Shared Neighborhood Hits	160
SwissProt Accessions	Q9H2G9, O15298, Q5T531, Q9GZX4	Gene names	BLZF1, JEM1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor).

GO45_MOUSE
θ value	θ > 10 (rank : 1701)	NC score	0.107923 (rank : 1396)
Query Neighborhood Hits	1371	Target Neighborhood Hits	139	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R2X8, Q3TJC4, Q8C0U6, Q9DAV7	Gene names	Blzf1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1).

GP137_HUMAN
θ value	θ > 10 (rank : 1702)	NC score	0.064426 (rank : 1818)
Query Neighborhood Hits	1371	Target Neighborhood Hits	119	Shared Neighborhood Hits	68
SwissProt Accessions	Q14444, Q15074	Gene names	M11S1, GPIP137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI) (Membrane component chromosome 11 surface marker 1).

GP73_MOUSE
θ value	θ > 10 (rank : 1703)	NC score	0.283034 (rank : 600)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	326
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GPS2_HUMAN
θ value	θ > 10 (rank : 1704)	NC score	0.194795 (rank : 862)
Query Neighborhood Hits	1371	Target Neighborhood Hits	459	Shared Neighborhood Hits	228
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GRB10_HUMAN
θ value	θ > 10 (rank : 1705)	NC score	0.060759 (rank : 1867)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	57
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	θ > 10 (rank : 1706)	NC score	0.061198 (rank : 1861)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB14_HUMAN
θ value	θ > 10 (rank : 1707)	NC score	0.081755 (rank : 1618)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	58
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB14_MOUSE
θ value	θ > 10 (rank : 1708)	NC score	0.083700 (rank : 1602)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_HUMAN
θ value	θ > 10 (rank : 1709)	NC score	0.065278 (rank : 1811)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	61
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	θ > 10 (rank : 1710)	NC score	0.074290 (rank : 1701)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	65
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

GRP3_HUMAN
θ value	θ > 10 (rank : 1711)	NC score	0.070259 (rank : 1749)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

HAP1_MOUSE
θ value	θ > 10 (rank : 1712)	NC score	0.232783 (rank : 746)
Query Neighborhood Hits	1371	Target Neighborhood Hits	388	Shared Neighborhood Hits	270
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HC127_HUMAN
θ value	θ > 10 (rank : 1713)	NC score	0.247808 (rank : 701)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	245
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
θ value	θ > 10 (rank : 1714)	NC score	0.247808 (rank : 702)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	245
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

HDAC5_HUMAN
θ value	θ > 10 (rank : 1715)	NC score	0.106911 (rank : 1410)
Query Neighborhood Hits	1371	Target Neighborhood Hits	353	Shared Neighborhood Hits	244
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

HDAC5_MOUSE
θ value	θ > 10 (rank : 1716)	NC score	0.074401 (rank : 1700)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

HDAC9_HUMAN
θ value	θ > 10 (rank : 1717)	NC score	0.052856 (rank : 2062)
Query Neighborhood Hits	1371	Target Neighborhood Hits	201	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

HDAC9_MOUSE
θ value	θ > 10 (rank : 1718)	NC score	0.101581 (rank : 1449)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	135
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

HGS_HUMAN
θ value	θ > 10 (rank : 1719)	NC score	0.147486 (rank : 1112)
Query Neighborhood Hits	1371	Target Neighborhood Hits	517	Shared Neighborhood Hits	194
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 1720)	NC score	0.144995 (rank : 1130)
Query Neighborhood Hits	1371	Target Neighborhood Hits	589	Shared Neighborhood Hits	198
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HIRP3_HUMAN
θ value	θ > 10 (rank : 1721)	NC score	0.127063 (rank : 1260)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	154
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

HNRCL_HUMAN
θ value	θ > 10 (rank : 1722)	NC score	0.055207 (rank : 1980)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	100
SwissProt Accessions	O60812	Gene names	HNRPCL1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP core protein C-like 1).

HOME2_HUMAN
θ value	θ > 10 (rank : 1723)	NC score	0.327119 (rank : 505)
Query Neighborhood Hits	1371	Target Neighborhood Hits	532	Shared Neighborhood Hits	399
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

HOME3_HUMAN
θ value	θ > 10 (rank : 1724)	NC score	0.181655 (rank : 914)
Query Neighborhood Hits	1371	Target Neighborhood Hits	275	Shared Neighborhood Hits	211
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HOME3_MOUSE
θ value	θ > 10 (rank : 1725)	NC score	0.182908 (rank : 908)
Query Neighborhood Hits	1371	Target Neighborhood Hits	316	Shared Neighborhood Hits	235
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HSF2B_HUMAN
θ value	θ > 10 (rank : 1726)	NC score	0.093769 (rank : 1506)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	82
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

HSF2_HUMAN
θ value	θ > 10 (rank : 1727)	NC score	0.054054 (rank : 2016)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	100
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSF2_MOUSE
θ value	θ > 10 (rank : 1728)	NC score	0.052746 (rank : 2067)
Query Neighborhood Hits	1371	Target Neighborhood Hits	153	Shared Neighborhood Hits	103
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSH2D_HUMAN
θ value	θ > 10 (rank : 1729)	NC score	0.082502 (rank : 1615)
Query Neighborhood Hits	1371	Target Neighborhood Hits	159	Shared Neighborhood Hits	59
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HSH2D_MOUSE
θ value	θ > 10 (rank : 1730)	NC score	0.056970 (rank : 1946)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HSP74_MOUSE
θ value	θ > 10 (rank : 1731)	NC score	0.053926 (rank : 2023)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	143
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HTSF1_HUMAN
θ value	θ > 10 (rank : 1732)	NC score	0.095553 (rank : 1492)
Query Neighborhood Hits	1371	Target Neighborhood Hits	408	Shared Neighborhood Hits	151
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

HTSF1_MOUSE
θ value	θ > 10 (rank : 1733)	NC score	0.060150 (rank : 1881)
Query Neighborhood Hits	1371	Target Neighborhood Hits	425	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

IF31_HUMAN
θ value	θ > 10 (rank : 1734)	NC score	0.061422 (rank : 1860)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

IF31_MOUSE
θ value	θ > 10 (rank : 1735)	NC score	0.074722 (rank : 1695)
Query Neighborhood Hits	1371	Target Neighborhood Hits	105	Shared Neighborhood Hits	73
SwissProt Accessions	Q66JS6, Q8BUW6	Gene names	Eif3s1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha).

IGF1R_HUMAN
θ value	θ > 10 (rank : 1736)	NC score	0.052949 (rank : 2060)
Query Neighborhood Hits	1371	Target Neighborhood Hits	977	Shared Neighborhood Hits	95
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 1737)	NC score	0.053031 (rank : 2056)
Query Neighborhood Hits	1371	Target Neighborhood Hits	973	Shared Neighborhood Hits	94
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IKKB_HUMAN
θ value	θ > 10 (rank : 1738)	NC score	0.063488 (rank : 1829)
Query Neighborhood Hits	1371	Target Neighborhood Hits	980	Shared Neighborhood Hits	210
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

ILK1_HUMAN
θ value	θ > 10 (rank : 1739)	NC score	0.064900 (rank : 1815)
Query Neighborhood Hits	1371	Target Neighborhood Hits	857	Shared Neighborhood Hits	113
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	θ > 10 (rank : 1740)	NC score	0.064337 (rank : 1820)
Query Neighborhood Hits	1371	Target Neighborhood Hits	848	Shared Neighborhood Hits	113
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	θ > 10 (rank : 1741)	NC score	0.065171 (rank : 1812)
Query Neighborhood Hits	1371	Target Neighborhood Hits	858	Shared Neighborhood Hits	113
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

IMMT_MOUSE
θ value	θ > 10 (rank : 1742)	NC score	0.211112 (rank : 815)
Query Neighborhood Hits	1371	Target Neighborhood Hits	326	Shared Neighborhood Hits	241
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

INSRR_HUMAN
θ value	θ > 10 (rank : 1743)	NC score	0.052678 (rank : 2072)
Query Neighborhood Hits	1371	Target Neighborhood Hits	950	Shared Neighborhood Hits	93
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 1744)	NC score	0.052717 (rank : 2070)
Query Neighborhood Hits	1371	Target Neighborhood Hits	961	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 1745)	NC score	0.051974 (rank : 2104)
Query Neighborhood Hits	1371	Target Neighborhood Hits	963	Shared Neighborhood Hits	94
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 1746)	NC score	0.052312 (rank : 2089)
Query Neighborhood Hits	1371	Target Neighborhood Hits	968	Shared Neighborhood Hits	96
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IQGA1_MOUSE
θ value	θ > 10 (rank : 1747)	NC score	0.084097 (rank : 1594)
Query Neighborhood Hits	1371	Target Neighborhood Hits	219	Shared Neighborhood Hits	134
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

IQGA2_HUMAN
θ value	θ > 10 (rank : 1748)	NC score	0.058675 (rank : 1907)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

IRAK1_HUMAN
θ value	θ > 10 (rank : 1749)	NC score	0.052510 (rank : 2081)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	97
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 1750)	NC score	0.055288 (rank : 1979)
Query Neighborhood Hits	1371	Target Neighborhood Hits	784	Shared Neighborhood Hits	92
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRAK2_HUMAN
θ value	θ > 10 (rank : 1751)	NC score	0.050873 (rank : 2151)
Query Neighborhood Hits	1371	Target Neighborhood Hits	714	Shared Neighborhood Hits	91
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

IRAK4_HUMAN
θ value	θ > 10 (rank : 1752)	NC score	0.053380 (rank : 2039)
Query Neighborhood Hits	1371	Target Neighborhood Hits	816	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

IRAK4_MOUSE
θ value	θ > 10 (rank : 1753)	NC score	0.053215 (rank : 2047)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	96
SwissProt Accessions	Q8R4K2, Q80WW1	Gene names	Irak4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4).

IWS1_HUMAN
θ value	θ > 10 (rank : 1754)	NC score	0.071354 (rank : 1738)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1241	Shared Neighborhood Hits	244
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 1755)	NC score	0.054251 (rank : 2012)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1258	Shared Neighborhood Hits	216
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JAK1_HUMAN
θ value	θ > 10 (rank : 1756)	NC score	0.051057 (rank : 2143)
Query Neighborhood Hits	1371	Target Neighborhood Hits	858	Shared Neighborhood Hits	99
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 1757)	NC score	0.050458 (rank : 2166)
Query Neighborhood Hits	1371	Target Neighborhood Hits	854	Shared Neighborhood Hits	96
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK2_HUMAN
θ value	θ > 10 (rank : 1758)	NC score	0.051188 (rank : 2138)
Query Neighborhood Hits	1371	Target Neighborhood Hits	847	Shared Neighborhood Hits	99
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK2_MOUSE
θ value	θ > 10 (rank : 1759)	NC score	0.051504 (rank : 2121)
Query Neighborhood Hits	1371	Target Neighborhood Hits	839	Shared Neighborhood Hits	99
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK3_HUMAN
θ value	θ > 10 (rank : 1760)	NC score	0.053944 (rank : 2021)
Query Neighborhood Hits	1371	Target Neighborhood Hits	827	Shared Neighborhood Hits	95
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

JAK3_MOUSE
θ value	θ > 10 (rank : 1761)	NC score	0.052285 (rank : 2092)
Query Neighborhood Hits	1371	Target Neighborhood Hits	821	Shared Neighborhood Hits	94
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

JIP2_HUMAN
θ value	θ > 10 (rank : 1762)	NC score	0.069798 (rank : 1757)
Query Neighborhood Hits	1371	Target Neighborhood Hits	288	Shared Neighborhood Hits	80
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
θ value	θ > 10 (rank : 1763)	NC score	0.065327 (rank : 1810)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP4_HUMAN
θ value	θ > 10 (rank : 1764)	NC score	0.206885 (rank : 828)
Query Neighborhood Hits	1371	Target Neighborhood Hits	585	Shared Neighborhood Hits	366
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

JIP4_MOUSE
θ value	θ > 10 (rank : 1765)	NC score	0.194180 (rank : 866)
Query Neighborhood Hits	1371	Target Neighborhood Hits	593	Shared Neighborhood Hits	359
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

K0100_HUMAN
θ value	θ > 10 (rank : 1766)	NC score	0.055983 (rank : 1968)
Query Neighborhood Hits	1371	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	Q14667, Q3SYN5, Q49A07, Q5H9T4, Q6WG74, Q6ZP51, Q96HH8	Gene names	KIAA0100, BCOX1
Domain Architecture	No domain graphic available
Description	UPF0378 family protein KIAA0100 precursor (Breast cancer overexpressed gene 1 protein) (Antigen MLAA-22).

K0494_HUMAN
θ value	θ > 10 (rank : 1767)	NC score	0.207827 (rank : 827)
Query Neighborhood Hits	1371	Target Neighborhood Hits	230	Shared Neighborhood Hits	180
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

K0841_HUMAN
θ value	θ > 10 (rank : 1768)	NC score	0.074516 (rank : 1697)
Query Neighborhood Hits	1371	Target Neighborhood Hits	119	Shared Neighborhood Hits	91
SwissProt Accessions	O94927, Q6P2P7, Q7L3D5, Q96CT8	Gene names	KIAA0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

K1377_HUMAN
θ value	θ > 10 (rank : 1769)	NC score	0.100724 (rank : 1457)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	101
SwissProt Accessions	Q9P2H0, Q4G0U6	Gene names	KIAA1377
Domain Architecture	No domain graphic available
Description	Protein KIAA1377.

K1914_HUMAN
θ value	θ > 10 (rank : 1770)	NC score	0.113462 (rank : 1361)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	159
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1914_MOUSE
θ value	θ > 10 (rank : 1771)	NC score	0.076170 (rank : 1676)
Query Neighborhood Hits	1371	Target Neighborhood Hits	216	Shared Neighborhood Hits	105
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1967_MOUSE
θ value	θ > 10 (rank : 1772)	NC score	0.054988 (rank : 1988)
Query Neighborhood Hits	1371	Target Neighborhood Hits	136	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

K1C10_HUMAN
θ value	θ > 10 (rank : 1773)	NC score	0.187971 (rank : 884)
Query Neighborhood Hits	1371	Target Neighborhood Hits	526	Shared Neighborhood Hits	377
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

K1C12_HUMAN
θ value	θ > 10 (rank : 1774)	NC score	0.133781 (rank : 1203)
Query Neighborhood Hits	1371	Target Neighborhood Hits	372	Shared Neighborhood Hits	287
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

K1C12_MOUSE
θ value	θ > 10 (rank : 1775)	NC score	0.146846 (rank : 1120)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	313
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

K1C13_HUMAN
θ value	θ > 10 (rank : 1776)	NC score	0.139707 (rank : 1165)
Query Neighborhood Hits	1371	Target Neighborhood Hits	386	Shared Neighborhood Hits	302
SwissProt Accessions	P13646, Q53G54, Q6AZK5, Q8N240	Gene names	KRT13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13).

K1C13_MOUSE
θ value	θ > 10 (rank : 1777)	NC score	0.154711 (rank : 1074)
Query Neighborhood Hits	1371	Target Neighborhood Hits	410	Shared Neighborhood Hits	321
SwissProt Accessions	P08730, Q3V176, Q6PAI1	Gene names	Krt13, Krt1-13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13) (47 kDa cytokeratin).

K1C14_HUMAN
θ value	θ > 10 (rank : 1778)	NC score	0.178608 (rank : 933)
Query Neighborhood Hits	1371	Target Neighborhood Hits	491	Shared Neighborhood Hits	384
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

K1C14_MOUSE
θ value	θ > 10 (rank : 1779)	NC score	0.186719 (rank : 893)
Query Neighborhood Hits	1371	Target Neighborhood Hits	501	Shared Neighborhood Hits	388
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

K1C15_HUMAN
θ value	θ > 10 (rank : 1780)	NC score	0.134961 (rank : 1192)
Query Neighborhood Hits	1371	Target Neighborhood Hits	367	Shared Neighborhood Hits	284
SwissProt Accessions	P19012, Q53XV8, Q9BUG4	Gene names	KRT15, KRTB
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

K1C16_HUMAN
θ value	θ > 10 (rank : 1781)	NC score	0.162145 (rank : 1024)
Query Neighborhood Hits	1371	Target Neighborhood Hits	440	Shared Neighborhood Hits	337
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

K1C17_HUMAN
θ value	θ > 10 (rank : 1782)	NC score	0.181385 (rank : 918)
Query Neighborhood Hits	1371	Target Neighborhood Hits	463	Shared Neighborhood Hits	359
SwissProt Accessions	Q04695	Gene names	KRT17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1).

K1C17_MOUSE
θ value	θ > 10 (rank : 1783)	NC score	0.176294 (rank : 943)
Query Neighborhood Hits	1371	Target Neighborhood Hits	456	Shared Neighborhood Hits	346
SwissProt Accessions	Q9QWL7, Q61783	Gene names	Krt17, Krt1-17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17).

K1C19_HUMAN
θ value	θ > 10 (rank : 1784)	NC score	0.113944 (rank : 1356)
Query Neighborhood Hits	1371	Target Neighborhood Hits	320	Shared Neighborhood Hits	246
SwissProt Accessions	P08727, Q5XG83, Q6NW33, Q7L5M9, Q96A53, Q96FV1, Q9BYF9, Q9P1Y4	Gene names	KRT19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

K1C19_MOUSE
θ value	θ > 10 (rank : 1785)	NC score	0.125828 (rank : 1265)
Query Neighborhood Hits	1371	Target Neighborhood Hits	358	Shared Neighborhood Hits	277
SwissProt Accessions	P19001	Gene names	Krt19, Krt1-19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

K1C23_HUMAN
θ value	θ > 10 (rank : 1786)	NC score	0.123043 (rank : 1280)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	239
SwissProt Accessions	Q9C075, Q9NUR6	Gene names	KRT23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

K1C9_HUMAN
θ value	θ > 10 (rank : 1787)	NC score	0.197058 (rank : 852)
Query Neighborhood Hits	1371	Target Neighborhood Hits	526	Shared Neighborhood Hits	374
SwissProt Accessions	P35527, O00109, Q14665	Gene names	KRT9
Domain Architecture
Description	Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9).

K1H1_HUMAN
θ value	θ > 10 (rank : 1788)	NC score	0.163769 (rank : 1018)
Query Neighborhood Hits	1371	Target Neighborhood Hits	433	Shared Neighborhood Hits	315
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

K1H1_MOUSE
θ value	θ > 10 (rank : 1789)	NC score	0.172775 (rank : 968)
Query Neighborhood Hits	1371	Target Neighborhood Hits	450	Shared Neighborhood Hits	342
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

K1H5_HUMAN
θ value	θ > 10 (rank : 1790)	NC score	0.117274 (rank : 1320)
Query Neighborhood Hits	1371	Target Neighborhood Hits	362	Shared Neighborhood Hits	243
SwissProt Accessions	Q92764, O76012, Q92651	Gene names	KRTHA5, HHA5, HKA5
Domain Architecture
Description	Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5).

K1H6_HUMAN
θ value	θ > 10 (rank : 1791)	NC score	0.155725 (rank : 1072)
Query Neighborhood Hits	1371	Target Neighborhood Hits	408	Shared Neighborhood Hits	320
SwissProt Accessions	O76013	Gene names	KRTHA6, HHA6, HKA6
Domain Architecture
Description	Keratin, type I cuticular Ha6 (Hair keratin, type I Ha6).

K22O_HUMAN
θ value	θ > 10 (rank : 1792)	NC score	0.144787 (rank : 1132)
Query Neighborhood Hits	1371	Target Neighborhood Hits	485	Shared Neighborhood Hits	319
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

K2C3_HUMAN
θ value	θ > 10 (rank : 1793)	NC score	0.133930 (rank : 1199)
Query Neighborhood Hits	1371	Target Neighborhood Hits	443	Shared Neighborhood Hits	287
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

K2C4_MOUSE
θ value	θ > 10 (rank : 1794)	NC score	0.187583 (rank : 885)
Query Neighborhood Hits	1371	Target Neighborhood Hits	521	Shared Neighborhood Hits	389
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

K2C5_HUMAN
θ value	θ > 10 (rank : 1795)	NC score	0.176639 (rank : 941)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	383
SwissProt Accessions	P13647, Q6PI71, Q6UBJ0, Q8TA91	Gene names	KRT5
Domain Architecture
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin).

K2C6A_HUMAN
θ value	θ > 10 (rank : 1796)	NC score	0.175024 (rank : 953)
Query Neighborhood Hits	1371	Target Neighborhood Hits	505	Shared Neighborhood Hits	382
SwissProt Accessions	P02538, Q6NT67, Q96CL4	Gene names	KRT6A, K6A
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin).

K2C6A_MOUSE
θ value	θ > 10 (rank : 1797)	NC score	0.168599 (rank : 991)
Query Neighborhood Hits	1371	Target Neighborhood Hits	481	Shared Neighborhood Hits	357
SwissProt Accessions	P50446, Q9Z332	Gene names	Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin) (Keratin-6 alpha) (mK6-alpha).

K2C6B_MOUSE
θ value	θ > 10 (rank : 1798)	NC score	0.175195 (rank : 950)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	378
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

K2C6C_HUMAN
θ value	θ > 10 (rank : 1799)	NC score	0.175175 (rank : 951)
Query Neighborhood Hits	1371	Target Neighborhood Hits	503	Shared Neighborhood Hits	379
SwissProt Accessions	P48666	Gene names	KRT6C
Domain Architecture
Description	Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin).

K2C6G_MOUSE
θ value	θ > 10 (rank : 1800)	NC score	0.161718 (rank : 1025)
Query Neighborhood Hits	1371	Target Neighborhood Hits	452	Shared Neighborhood Hits	325
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

K2C7_HUMAN
θ value	θ > 10 (rank : 1801)	NC score	0.131436 (rank : 1227)
Query Neighborhood Hits	1371	Target Neighborhood Hits	369	Shared Neighborhood Hits	272
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

K2C8_HUMAN
θ value	θ > 10 (rank : 1802)	NC score	0.211087 (rank : 816)
Query Neighborhood Hits	1371	Target Neighborhood Hits	593	Shared Neighborhood Hits	424
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

K2C8_MOUSE
θ value	θ > 10 (rank : 1803)	NC score	0.210977 (rank : 817)
Query Neighborhood Hits	1371	Target Neighborhood Hits	576	Shared Neighborhood Hits	418
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

KGP2_MOUSE
θ value	θ > 10 (rank : 1804)	NC score	0.057886 (rank : 1931)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1029	Shared Neighborhood Hits	220
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 1805)	NC score	0.050930 (rank : 2149)
Query Neighborhood Hits	1371	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KI18A_HUMAN
θ value	θ > 10 (rank : 1806)	NC score	0.094193 (rank : 1503)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	113
SwissProt Accessions	Q8NI77, Q86VS5, Q9H0F3	Gene names	KIF18A
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

KI20A_HUMAN
θ value	θ > 10 (rank : 1807)	NC score	0.174248 (rank : 960)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	237
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

KI20A_MOUSE
θ value	θ > 10 (rank : 1808)	NC score	0.165491 (rank : 1006)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	232
SwissProt Accessions	P97329, Q542M4	Gene names	Kif20a, Rab6kifl
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (Kinesin-like protein 174).

KI67_HUMAN
θ value	θ > 10 (rank : 1809)	NC score	0.054307 (rank : 2009)
Query Neighborhood Hits	1371	Target Neighborhood Hits	581	Shared Neighborhood Hits	153
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIF11_HUMAN
θ value	θ > 10 (rank : 1810)	NC score	0.263101 (rank : 652)
Query Neighborhood Hits	1371	Target Neighborhood Hits	583	Shared Neighborhood Hits	414
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

KIF12_HUMAN
θ value	θ > 10 (rank : 1811)	NC score	0.084103 (rank : 1592)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	91
SwissProt Accessions	Q96FN5, Q5TBE0	Gene names	KIF12
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF12.

KIF12_MOUSE
θ value	θ > 10 (rank : 1812)	NC score	0.073540 (rank : 1710)
Query Neighborhood Hits	1371	Target Neighborhood Hits	94	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D2Z8, O35061	Gene names	Kif12
Domain Architecture
Description	Kinesin-like protein KIF12.

KIF17_MOUSE
θ value	θ > 10 (rank : 1813)	NC score	0.136315 (rank : 1186)
Query Neighborhood Hits	1371	Target Neighborhood Hits	452	Shared Neighborhood Hits	276
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

KIF1B_HUMAN
θ value	θ > 10 (rank : 1814)	NC score	0.084625 (rank : 1587)
Query Neighborhood Hits	1371	Target Neighborhood Hits	178	Shared Neighborhood Hits	102
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

KIF1B_MOUSE
θ value	θ > 10 (rank : 1815)	NC score	0.081110 (rank : 1625)
Query Neighborhood Hits	1371	Target Neighborhood Hits	167	Shared Neighborhood Hits	86
SwissProt Accessions	Q60575, Q9R0B4, Q9WVE5, Q9Z119	Gene names	Kif1b
Domain Architecture
Description	Kinesin-like protein KIF1B.

KIF1C_HUMAN
θ value	θ > 10 (rank : 1816)	NC score	0.072006 (rank : 1731)
Query Neighborhood Hits	1371	Target Neighborhood Hits	128	Shared Neighborhood Hits	58
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KIF1C_MOUSE
θ value	θ > 10 (rank : 1817)	NC score	0.072319 (rank : 1725)
Query Neighborhood Hits	1371	Target Neighborhood Hits	171	Shared Neighborhood Hits	69
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KIF22_HUMAN
θ value	θ > 10 (rank : 1818)	NC score	0.080508 (rank : 1628)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	70
SwissProt Accessions	Q14807, O94814, Q9BT46	Gene names	KIF22, KID, KNSL4
Domain Architecture
Description	Kinesin-like protein KIF22 (Kinesin-like DNA-binding protein) (Kinesin-like protein 4).

KIF25_HUMAN
θ value	θ > 10 (rank : 1819)	NC score	0.073850 (rank : 1706)
Query Neighborhood Hits	1371	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIL4, O94775	Gene names	KIF25, KNSL3
Domain Architecture
Description	Kinesin-like protein KIF25 (Kinesin-like protein 3).

KIF2A_HUMAN
θ value	θ > 10 (rank : 1820)	NC score	0.069483 (rank : 1759)
Query Neighborhood Hits	1371	Target Neighborhood Hits	94	Shared Neighborhood Hits	47
SwissProt Accessions	O00139, Q8N5Q7	Gene names	KIF2A, KIF2, KNS2
Domain Architecture
Description	Kinesin-like protein KIF2A (Kinesin-2) (HK2).

KIF2A_MOUSE
θ value	θ > 10 (rank : 1821)	NC score	0.068895 (rank : 1765)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P28740	Gene names	Kif2a, Kif2, Kns2
Domain Architecture
Description	Kinesin-like protein KIF2A.

KIF2B_HUMAN
θ value	θ > 10 (rank : 1822)	NC score	0.066746 (rank : 1796)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N4N8, Q96MA2, Q9BXG6	Gene names	KIF2B
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF2B.

KIF2B_MOUSE
θ value	θ > 10 (rank : 1823)	NC score	0.066673 (rank : 1798)
Query Neighborhood Hits	1371	Target Neighborhood Hits	63	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C0N1	Gene names	Kif2b
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF2B.

KIF2C_MOUSE
θ value	θ > 10 (rank : 1824)	NC score	0.069422 (rank : 1761)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	53
SwissProt Accessions	Q922S8	Gene names	Kif2c
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK).

KIF3C_MOUSE
θ value	θ > 10 (rank : 1825)	NC score	0.207848 (rank : 826)
Query Neighborhood Hits	1371	Target Neighborhood Hits	468	Shared Neighborhood Hits	364
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

KIF9_HUMAN
θ value	θ > 10 (rank : 1826)	NC score	0.077243 (rank : 1664)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAQ2, Q86Z28, Q9H8A4	Gene names	KIF9
Domain Architecture
Description	Kinesin-like protein KIF9.

KIF9_MOUSE
θ value	θ > 10 (rank : 1827)	NC score	0.085201 (rank : 1584)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WV04, O35070	Gene names	Kif9
Domain Architecture
Description	Kinesin-like protein KIF9.

KIFC2_HUMAN
θ value	θ > 10 (rank : 1828)	NC score	0.106314 (rank : 1416)
Query Neighborhood Hits	1371	Target Neighborhood Hits	237	Shared Neighborhood Hits	139
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

KIFC2_MOUSE
θ value	θ > 10 (rank : 1829)	NC score	0.110184 (rank : 1378)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	141
SwissProt Accessions	O08672, O08613	Gene names	Kifc2
Domain Architecture
Description	Kinesin-like protein KIFC2.

KLC1_HUMAN
θ value	θ > 10 (rank : 1830)	NC score	0.171736 (rank : 975)
Query Neighborhood Hits	1371	Target Neighborhood Hits	471	Shared Neighborhood Hits	328
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

KLC1_MOUSE
θ value	θ > 10 (rank : 1831)	NC score	0.132041 (rank : 1219)
Query Neighborhood Hits	1371	Target Neighborhood Hits	357	Shared Neighborhood Hits	254
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

KLC2_MOUSE
θ value	θ > 10 (rank : 1832)	NC score	0.054429 (rank : 2000)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	156
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

KLC4_HUMAN
θ value	θ > 10 (rank : 1833)	NC score	0.109933 (rank : 1380)
Query Neighborhood Hits	1371	Target Neighborhood Hits	327	Shared Neighborhood Hits	229
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

KLC4_MOUSE
θ value	θ > 10 (rank : 1834)	NC score	0.108935 (rank : 1386)
Query Neighborhood Hits	1371	Target Neighborhood Hits	336	Shared Neighborhood Hits	234
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

KPCD_HUMAN
θ value	θ > 10 (rank : 1835)	NC score	0.054397 (rank : 2005)
Query Neighborhood Hits	1371	Target Neighborhood Hits	900	Shared Neighborhood Hits	114
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCD_MOUSE
θ value	θ > 10 (rank : 1836)	NC score	0.054885 (rank : 1990)
Query Neighborhood Hits	1371	Target Neighborhood Hits	888	Shared Neighborhood Hits	112
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCE_HUMAN
θ value	θ > 10 (rank : 1837)	NC score	0.057159 (rank : 1943)
Query Neighborhood Hits	1371	Target Neighborhood Hits	906	Shared Neighborhood Hits	128
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
θ value	θ > 10 (rank : 1838)	NC score	0.057216 (rank : 1941)
Query Neighborhood Hits	1371	Target Neighborhood Hits	906	Shared Neighborhood Hits	127
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCL_HUMAN
θ value	θ > 10 (rank : 1839)	NC score	0.052803 (rank : 2063)
Query Neighborhood Hits	1371	Target Neighborhood Hits	887	Shared Neighborhood Hits	121
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCL_MOUSE
θ value	θ > 10 (rank : 1840)	NC score	0.053605 (rank : 2033)
Query Neighborhood Hits	1371	Target Neighborhood Hits	891	Shared Neighborhood Hits	125
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCT_HUMAN
θ value	θ > 10 (rank : 1841)	NC score	0.055110 (rank : 1982)
Query Neighborhood Hits	1371	Target Neighborhood Hits	897	Shared Neighborhood Hits	111
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	θ > 10 (rank : 1842)	NC score	0.055017 (rank : 1987)
Query Neighborhood Hits	1371	Target Neighborhood Hits	895	Shared Neighborhood Hits	111
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KRHB1_HUMAN
θ value	θ > 10 (rank : 1843)	NC score	0.136707 (rank : 1183)
Query Neighborhood Hits	1371	Target Neighborhood Hits	461	Shared Neighborhood Hits	311
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB2_HUMAN
θ value	θ > 10 (rank : 1844)	NC score	0.079131 (rank : 1648)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NSB4	Gene names	KRTHB2
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

KRHB2_MOUSE
θ value	θ > 10 (rank : 1845)	NC score	0.081968 (rank : 1617)
Query Neighborhood Hits	1371	Target Neighborhood Hits	233	Shared Neighborhood Hits	166
SwissProt Accessions	Q99M74	Gene names	Krthb2, Krt2-20
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

KRHB3_HUMAN
θ value	θ > 10 (rank : 1846)	NC score	0.133542 (rank : 1206)
Query Neighborhood Hits	1371	Target Neighborhood Hits	438	Shared Neighborhood Hits	305
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

KRHB4_HUMAN
θ value	θ > 10 (rank : 1847)	NC score	0.113817 (rank : 1358)
Query Neighborhood Hits	1371	Target Neighborhood Hits	352	Shared Neighborhood Hits	255
SwissProt Accessions	Q9NSB2	Gene names	KRTHB4
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4).

KRHB4_MOUSE
θ value	θ > 10 (rank : 1848)	NC score	0.115356 (rank : 1341)
Query Neighborhood Hits	1371	Target Neighborhood Hits	344	Shared Neighborhood Hits	257
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

KRHB5_HUMAN
θ value	θ > 10 (rank : 1849)	NC score	0.099379 (rank : 1467)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	235
SwissProt Accessions	P78386, Q9NSB1	Gene names	KRTHB5
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

KRHB5_MOUSE
θ value	θ > 10 (rank : 1850)	NC score	0.093021 (rank : 1512)
Query Neighborhood Hits	1371	Target Neighborhood Hits	294	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

KRHB6_HUMAN
θ value	θ > 10 (rank : 1851)	NC score	0.137951 (rank : 1177)
Query Neighborhood Hits	1371	Target Neighborhood Hits	447	Shared Neighborhood Hits	310
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

KRHB6_MOUSE
θ value	θ > 10 (rank : 1852)	NC score	0.124687 (rank : 1271)
Query Neighborhood Hits	1371	Target Neighborhood Hits	413	Shared Neighborhood Hits	289
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

KSR2_HUMAN
θ value	θ > 10 (rank : 1853)	NC score	0.053025 (rank : 2057)
Query Neighborhood Hits	1371	Target Neighborhood Hits	920	Shared Neighborhood Hits	108
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KSYK_HUMAN
θ value	θ > 10 (rank : 1854)	NC score	0.071078 (rank : 1739)
Query Neighborhood Hits	1371	Target Neighborhood Hits	901	Shared Neighborhood Hits	127
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 1855)	NC score	0.071740 (rank : 1734)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	130
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAD1_MOUSE
θ value	θ > 10 (rank : 1856)	NC score	0.065589 (rank : 1806)
Query Neighborhood Hits	1371	Target Neighborhood Hits	391	Shared Neighborhood Hits	125
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LAMA1_HUMAN
θ value	θ > 10 (rank : 1857)	NC score	0.082998 (rank : 1609)
Query Neighborhood Hits	1371	Target Neighborhood Hits	804	Shared Neighborhood Hits	237
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 1858)	NC score	0.173098 (rank : 965)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1092	Shared Neighborhood Hits	399
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 1859)	NC score	0.180556 (rank : 922)
Query Neighborhood Hits	1371	Target Neighborhood Hits	760	Shared Neighborhood Hits	329
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 1860)	NC score	0.136314 (rank : 1187)
Query Neighborhood Hits	1371	Target Neighborhood Hits	859	Shared Neighborhood Hits	321
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 1861)	NC score	0.194656 (rank : 863)
Query Neighborhood Hits	1371	Target Neighborhood Hits	708	Shared Neighborhood Hits	351
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 1862)	NC score	0.142567 (rank : 1145)
Query Neighborhood Hits	1371	Target Neighborhood Hits	584	Shared Neighborhood Hits	261
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 1863)	NC score	0.058242 (rank : 1920)
Query Neighborhood Hits	1371	Target Neighborhood Hits	976	Shared Neighborhood Hits	262
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	θ > 10 (rank : 1864)	NC score	0.055941 (rank : 1969)
Query Neighborhood Hits	1371	Target Neighborhood Hits	692	Shared Neighborhood Hits	187
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 1865)	NC score	0.064833 (rank : 1816)
Query Neighborhood Hits	1371	Target Neighborhood Hits	722	Shared Neighborhood Hits	239
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 1866)	NC score	0.072972 (rank : 1716)
Query Neighborhood Hits	1371	Target Neighborhood Hits	461	Shared Neighborhood Hits	186
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 1867)	NC score	0.183066 (rank : 906)
Query Neighborhood Hits	1371	Target Neighborhood Hits	922	Shared Neighborhood Hits	379
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 1868)	NC score	0.141902 (rank : 1151)
Query Neighborhood Hits	1371	Target Neighborhood Hits	715	Shared Neighborhood Hits	279
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 1869)	NC score	0.096033 (rank : 1487)
Query Neighborhood Hits	1371	Target Neighborhood Hits	614	Shared Neighborhood Hits	208
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LBN_HUMAN
θ value	θ > 10 (rank : 1870)	NC score	0.252456 (rank : 687)
Query Neighborhood Hits	1371	Target Neighborhood Hits	308	Shared Neighborhood Hits	246
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

LBN_MOUSE
θ value	θ > 10 (rank : 1871)	NC score	0.244315 (rank : 715)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	250
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

LC7L2_HUMAN
θ value	θ > 10 (rank : 1872)	NC score	0.130856 (rank : 1234)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

LC7L2_MOUSE
θ value	θ > 10 (rank : 1873)	NC score	0.133090 (rank : 1211)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	171
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

LCP2_HUMAN
θ value	θ > 10 (rank : 1874)	NC score	0.066154 (rank : 1803)
Query Neighborhood Hits	1371	Target Neighborhood Hits	531	Shared Neighborhood Hits	99
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LCP2_MOUSE
θ value	θ > 10 (rank : 1875)	NC score	0.068918 (rank : 1764)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	62
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LEO1_HUMAN
θ value	θ > 10 (rank : 1876)	NC score	0.054419 (rank : 2002)
Query Neighborhood Hits	1371	Target Neighborhood Hits	958	Shared Neighborhood Hits	203
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LETM1_HUMAN
θ value	θ > 10 (rank : 1877)	NC score	0.256743 (rank : 669)
Query Neighborhood Hits	1371	Target Neighborhood Hits	338	Shared Neighborhood Hits	264
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LETM1_MOUSE
θ value	θ > 10 (rank : 1878)	NC score	0.201940 (rank : 839)
Query Neighborhood Hits	1371	Target Neighborhood Hits	240	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LIMK1_HUMAN
θ value	θ > 10 (rank : 1879)	NC score	0.050627 (rank : 2162)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1005	Shared Neighborhood Hits	115
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
θ value	θ > 10 (rank : 1880)	NC score	0.050619 (rank : 2163)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1008	Shared Neighborhood Hits	114
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

LNK_HUMAN
θ value	θ > 10 (rank : 1881)	NC score	0.077054 (rank : 1667)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LNK_MOUSE
θ value	θ > 10 (rank : 1882)	NC score	0.074792 (rank : 1693)
Query Neighborhood Hits	1371	Target Neighborhood Hits	132	Shared Neighborhood Hits	56
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LRC48_HUMAN
θ value	θ > 10 (rank : 1883)	NC score	0.073523 (rank : 1711)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	124
SwissProt Accessions	Q9H069, Q86SF9, Q86W73, Q8IWG0	Gene names	LRRC48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

LRMP_HUMAN
θ value	θ > 10 (rank : 1884)	NC score	0.070005 (rank : 1752)
Query Neighborhood Hits	1371	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

LRMP_MOUSE
θ value	θ > 10 (rank : 1885)	NC score	0.056956 (rank : 1947)
Query Neighborhood Hits	1371	Target Neighborhood Hits	120	Shared Neighborhood Hits	79
SwissProt Accessions	Q60664, Q7TMU8	Gene names	Lrmp, Jaw1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

LRRF1_MOUSE
θ value	θ > 10 (rank : 1886)	NC score	0.145415 (rank : 1128)
Query Neighborhood Hits	1371	Target Neighborhood Hits	440	Shared Neighborhood Hits	221
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

LTK_HUMAN
θ value	θ > 10 (rank : 1887)	NC score	0.056840 (rank : 1948)
Query Neighborhood Hits	1371	Target Neighborhood Hits	774	Shared Neighborhood Hits	95
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 1888)	NC score	0.058077 (rank : 1922)
Query Neighborhood Hits	1371	Target Neighborhood Hits	770	Shared Neighborhood Hits	96
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LUC7L_HUMAN
θ value	θ > 10 (rank : 1889)	NC score	0.072109 (rank : 1729)
Query Neighborhood Hits	1371	Target Neighborhood Hits	130	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQ29, Q96S32, Q9NPH4	Gene names	LUC7L, LUC7L1
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 1 (SR+89) (Putative SR protein LUC7B1).

LUC7L_MOUSE
θ value	θ > 10 (rank : 1890)	NC score	0.062716 (rank : 1840)
Query Neighborhood Hits	1371	Target Neighborhood Hits	111	Shared Neighborhood Hits	78
SwissProt Accessions	Q9CYI4, Q8K247, Q9CWM1	Gene names	Luc7l
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 1.

LYAR_HUMAN
θ value	θ > 10 (rank : 1891)	NC score	0.060311 (rank : 1876)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NX58, Q6FI78, Q9NYS1	Gene names	LYAR
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

M3K12_HUMAN
θ value	θ > 10 (rank : 1892)	NC score	0.055061 (rank : 1985)
Query Neighborhood Hits	1371	Target Neighborhood Hits	940	Shared Neighborhood Hits	112
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	θ > 10 (rank : 1893)	NC score	0.055289 (rank : 1978)
Query Neighborhood Hits	1371	Target Neighborhood Hits	957	Shared Neighborhood Hits	117
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K13_HUMAN
θ value	θ > 10 (rank : 1894)	NC score	0.055078 (rank : 1983)
Query Neighborhood Hits	1371	Target Neighborhood Hits	911	Shared Neighborhood Hits	107
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K7_HUMAN
θ value	θ > 10 (rank : 1895)	NC score	0.056414 (rank : 1960)
Query Neighborhood Hits	1371	Target Neighborhood Hits	892	Shared Neighborhood Hits	133
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	θ > 10 (rank : 1896)	NC score	0.056659 (rank : 1953)
Query Neighborhood Hits	1371	Target Neighborhood Hits	892	Shared Neighborhood Hits	136
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M4K1_MOUSE
θ value	θ > 10 (rank : 1897)	NC score	0.050169 (rank : 2176)
Query Neighborhood Hits	1371	Target Neighborhood Hits	858	Shared Neighborhood Hits	96
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

MAML2_HUMAN
θ value	θ > 10 (rank : 1898)	NC score	0.101734 (rank : 1447)
Query Neighborhood Hits	1371	Target Neighborhood Hits	360	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MAST4_HUMAN
θ value	θ > 10 (rank : 1899)	NC score	0.050291 (rank : 2172)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1804	Shared Neighborhood Hits	224
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MAT1_HUMAN
θ value	θ > 10 (rank : 1900)	NC score	0.113912 (rank : 1357)
Query Neighborhood Hits	1371	Target Neighborhood Hits	179	Shared Neighborhood Hits	127
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 1901)	NC score	0.138942 (rank : 1169)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	158
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MATK_HUMAN
θ value	θ > 10 (rank : 1902)	NC score	0.082436 (rank : 1616)
Query Neighborhood Hits	1371	Target Neighborhood Hits	954	Shared Neighborhood Hits	149
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 1903)	NC score	0.083971 (rank : 1597)
Query Neighborhood Hits	1371	Target Neighborhood Hits	952	Shared Neighborhood Hits	153
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MDN1_HUMAN
θ value	θ > 10 (rank : 1904)	NC score	0.079242 (rank : 1646)
Query Neighborhood Hits	1371	Target Neighborhood Hits	662	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MED12_HUMAN
θ value	θ > 10 (rank : 1905)	NC score	0.128894 (rank : 1244)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	145
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

MERTK_HUMAN
θ value	θ > 10 (rank : 1906)	NC score	0.050013 (rank : 2181)
Query Neighborhood Hits	1371	Target Neighborhood Hits	988	Shared Neighborhood Hits	90
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MET_HUMAN
θ value	θ > 10 (rank : 1907)	NC score	0.053560 (rank : 2036)
Query Neighborhood Hits	1371	Target Neighborhood Hits	831	Shared Neighborhood Hits	95
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 1908)	NC score	0.054382 (rank : 2006)
Query Neighborhood Hits	1371	Target Neighborhood Hits	844	Shared Neighborhood Hits	94
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MICA1_MOUSE
θ value	θ > 10 (rank : 1909)	NC score	0.119911 (rank : 1305)
Query Neighborhood Hits	1371	Target Neighborhood Hits	400	Shared Neighborhood Hits	246
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 1910)	NC score	0.063174 (rank : 1833)
Query Neighborhood Hits	1371	Target Neighborhood Hits	457	Shared Neighborhood Hits	136
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MIPO1_MOUSE
θ value	θ > 10 (rank : 1911)	NC score	0.101148 (rank : 1454)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	86
SwissProt Accessions	Q9D9F8	Gene names	Mipol1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein homolog.

MLKL_HUMAN
θ value	θ > 10 (rank : 1912)	NC score	0.053989 (rank : 2017)
Query Neighborhood Hits	1371	Target Neighborhood Hits	600	Shared Neighborhood Hits	94
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 1913)	NC score	0.051963 (rank : 2105)
Query Neighborhood Hits	1371	Target Neighborhood Hits	707	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLL2_HUMAN
θ value	θ > 10 (rank : 1914)	NC score	0.120804 (rank : 1296)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1788	Shared Neighborhood Hits	385
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLTK_HUMAN
θ value	θ > 10 (rank : 1915)	NC score	0.058275 (rank : 1917)
Query Neighborhood Hits	1371	Target Neighborhood Hits	911	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	θ > 10 (rank : 1916)	NC score	0.058668 (rank : 1908)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MMRN2_HUMAN
θ value	θ > 10 (rank : 1917)	NC score	0.257083 (rank : 666)
Query Neighborhood Hits	1371	Target Neighborhood Hits	400	Shared Neighborhood Hits	259
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

MORC4_HUMAN
θ value	θ > 10 (rank : 1918)	NC score	0.121681 (rank : 1286)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	186
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

MORC4_MOUSE
θ value	θ > 10 (rank : 1919)	NC score	0.098431 (rank : 1474)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

MOS_HUMAN
θ value	θ > 10 (rank : 1920)	NC score	0.054288 (rank : 2010)
Query Neighborhood Hits	1371	Target Neighborhood Hits	829	Shared Neighborhood Hits	94
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MOS_MOUSE
θ value	θ > 10 (rank : 1921)	NC score	0.054850 (rank : 1991)
Query Neighborhood Hits	1371	Target Neighborhood Hits	833	Shared Neighborhood Hits	96
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MP2K7_HUMAN
θ value	θ > 10 (rank : 1922)	NC score	0.050152 (rank : 2177)
Query Neighborhood Hits	1371	Target Neighborhood Hits	833	Shared Neighborhood Hits	94
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

MPP10_HUMAN
θ value	θ > 10 (rank : 1923)	NC score	0.166670 (rank : 998)
Query Neighborhood Hits	1371	Target Neighborhood Hits	306	Shared Neighborhood Hits	198
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MPP10_MOUSE
θ value	θ > 10 (rank : 1924)	NC score	0.146989 (rank : 1115)
Query Neighborhood Hits	1371	Target Neighborhood Hits	251	Shared Neighborhood Hits	166
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MRIP_HUMAN
θ value	θ > 10 (rank : 1925)	NC score	0.287473 (rank : 588)
Query Neighborhood Hits	1371	Target Neighborhood Hits	578	Shared Neighborhood Hits	362
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	θ > 10 (rank : 1926)	NC score	0.289303 (rank : 584)
Query Neighborhood Hits	1371	Target Neighborhood Hits	569	Shared Neighborhood Hits	366
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MSRE_MOUSE
θ value	θ > 10 (rank : 1927)	NC score	0.062905 (rank : 1837)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	137
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

MST4_HUMAN
θ value	θ > 10 (rank : 1928)	NC score	0.052316 (rank : 2088)
Query Neighborhood Hits	1371	Target Neighborhood Hits	852	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MST4_MOUSE
θ value	θ > 10 (rank : 1929)	NC score	0.052295 (rank : 2091)
Query Neighborhood Hits	1371	Target Neighborhood Hits	860	Shared Neighborhood Hits	95
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

MTSS1_HUMAN
θ value	θ > 10 (rank : 1930)	NC score	0.070680 (rank : 1747)
Query Neighborhood Hits	1371	Target Neighborhood Hits	504	Shared Neighborhood Hits	140
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
θ value	θ > 10 (rank : 1931)	NC score	0.062201 (rank : 1849)
Query Neighborhood Hits	1371	Target Neighborhood Hits	592	Shared Neighborhood Hits	127
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUTED_HUMAN
θ value	θ > 10 (rank : 1932)	NC score	0.109940 (rank : 1379)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TDH9, Q5THS1, Q68D56, Q8N5F9, Q9NU16	Gene names	MUTED
Domain Architecture	No domain graphic available
Description	Muted protein homolog.

MUT_MOUSE
θ value	θ > 10 (rank : 1933)	NC score	0.051732 (rank : 2114)
Query Neighborhood Hits	1371	Target Neighborhood Hits	52	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R015, Q3TCP2, Q8CAC9	Gene names	Muted, Mu
Domain Architecture	No domain graphic available
Description	Muted protein.

MYO1A_HUMAN
θ value	θ > 10 (rank : 1934)	NC score	0.120340 (rank : 1299)
Query Neighborhood Hits	1371	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UBC5, Q9UQD7	Gene names	MYO1A, MYHL
Domain Architecture
Description	Myosin Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC).

MYO1B_HUMAN
θ value	θ > 10 (rank : 1935)	NC score	0.119564 (rank : 1307)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

MYO1B_MOUSE
θ value	θ > 10 (rank : 1936)	NC score	0.119301 (rank : 1309)
Query Neighborhood Hits	1371	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

MYO1C_HUMAN
θ value	θ > 10 (rank : 1937)	NC score	0.120165 (rank : 1303)
Query Neighborhood Hits	1371	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	O00159	Gene names	MYO1C
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMI-beta) (MMIb).

MYO1C_MOUSE
θ value	θ > 10 (rank : 1938)	NC score	0.120508 (rank : 1297)
Query Neighborhood Hits	1371	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTI7, O08571, O08834, Q9QW54	Gene names	Myo1c
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMIb).

MYO1D_HUMAN
θ value	θ > 10 (rank : 1939)	NC score	0.120173 (rank : 1302)
Query Neighborhood Hits	1371	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	O94832, Q8NHP9	Gene names	MYO1D, KIAA0727
Domain Architecture
Description	Myosin Id.

MYO1D_MOUSE
θ value	θ > 10 (rank : 1940)	NC score	0.119981 (rank : 1304)
Query Neighborhood Hits	1371	Target Neighborhood Hits	57	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SYD0, Q5SSK7, Q8BWY5	Gene names	Myo1d
Domain Architecture	No domain graphic available
Description	Myosin Id.

MYO3A_HUMAN
θ value	θ > 10 (rank : 1941)	NC score	0.117232 (rank : 1321)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1033	Shared Neighborhood Hits	214
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

MYO3A_MOUSE
θ value	θ > 10 (rank : 1942)	NC score	0.105145 (rank : 1424)
Query Neighborhood Hits	1371	Target Neighborhood Hits	902	Shared Neighborhood Hits	142
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

MYO3B_HUMAN
θ value	θ > 10 (rank : 1943)	NC score	0.106365 (rank : 1415)
Query Neighborhood Hits	1371	Target Neighborhood Hits	923	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

MYO7A_HUMAN
θ value	θ > 10 (rank : 1944)	NC score	0.140362 (rank : 1160)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	132
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	θ > 10 (rank : 1945)	NC score	0.148068 (rank : 1108)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	156
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO9B_HUMAN
θ value	θ > 10 (rank : 1946)	NC score	0.138533 (rank : 1172)
Query Neighborhood Hits	1371	Target Neighborhood Hits	641	Shared Neighborhood Hits	171
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	θ > 10 (rank : 1947)	NC score	0.134242 (rank : 1196)
Query Neighborhood Hits	1371	Target Neighborhood Hits	311	Shared Neighborhood Hits	121
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYOC_HUMAN
θ value	θ > 10 (rank : 1948)	NC score	0.175727 (rank : 948)
Query Neighborhood Hits	1371	Target Neighborhood Hits	489	Shared Neighborhood Hits	345
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MYOC_MOUSE
θ value	θ > 10 (rank : 1949)	NC score	0.083068 (rank : 1608)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	172
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MYPT1_HUMAN
θ value	θ > 10 (rank : 1950)	NC score	0.107683 (rank : 1398)
Query Neighborhood Hits	1371	Target Neighborhood Hits	723	Shared Neighborhood Hits	316
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	θ > 10 (rank : 1951)	NC score	0.053295 (rank : 2043)
Query Neighborhood Hits	1371	Target Neighborhood Hits	539	Shared Neighborhood Hits	158
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MYPT2_HUMAN
θ value	θ > 10 (rank : 1952)	NC score	0.101606 (rank : 1448)
Query Neighborhood Hits	1371	Target Neighborhood Hits	707	Shared Neighborhood Hits	317
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

MYRIP_HUMAN
θ value	θ > 10 (rank : 1953)	NC score	0.053238 (rank : 2046)
Query Neighborhood Hits	1371	Target Neighborhood Hits	269	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MYST3_HUMAN
θ value	θ > 10 (rank : 1954)	NC score	0.073021 (rank : 1714)
Query Neighborhood Hits	1371	Target Neighborhood Hits	772	Shared Neighborhood Hits	232
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST4_HUMAN
θ value	θ > 10 (rank : 1955)	NC score	0.052118 (rank : 2097)
Query Neighborhood Hits	1371	Target Neighborhood Hits	671	Shared Neighborhood Hits	196
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYT1L_HUMAN
θ value	θ > 10 (rank : 1956)	NC score	0.099389 (rank : 1466)
Query Neighborhood Hits	1371	Target Neighborhood Hits	471	Shared Neighborhood Hits	244
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

MYT1L_MOUSE
θ value	θ > 10 (rank : 1957)	NC score	0.095071 (rank : 1496)
Query Neighborhood Hits	1371	Target Neighborhood Hits	461	Shared Neighborhood Hits	237
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

MYT1_HUMAN
θ value	θ > 10 (rank : 1958)	NC score	0.079891 (rank : 1639)
Query Neighborhood Hits	1371	Target Neighborhood Hits	475	Shared Neighborhood Hits	225
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

MYT1_MOUSE
θ value	θ > 10 (rank : 1959)	NC score	0.050284 (rank : 2173)
Query Neighborhood Hits	1371	Target Neighborhood Hits	385	Shared Neighborhood Hits	170
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NASP_HUMAN
θ value	θ > 10 (rank : 1960)	NC score	0.166535 (rank : 999)
Query Neighborhood Hits	1371	Target Neighborhood Hits	709	Shared Neighborhood Hits	267
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCOR1_HUMAN
θ value	θ > 10 (rank : 1961)	NC score	0.065494 (rank : 1807)
Query Neighborhood Hits	1371	Target Neighborhood Hits	577	Shared Neighborhood Hits	171
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR1_MOUSE
θ value	θ > 10 (rank : 1962)	NC score	0.060423 (rank : 1874)
Query Neighborhood Hits	1371	Target Neighborhood Hits	521	Shared Neighborhood Hits	157
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NDE1_MOUSE
θ value	θ > 10 (rank : 1963)	NC score	0.336844 (rank : 490)
Query Neighborhood Hits	1371	Target Neighborhood Hits	602	Shared Neighborhood Hits	450
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

NDEL1_HUMAN
θ value	θ > 10 (rank : 1964)	NC score	0.284525 (rank : 595)
Query Neighborhood Hits	1371	Target Neighborhood Hits	415	Shared Neighborhood Hits	335
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

NDEL1_MOUSE
θ value	θ > 10 (rank : 1965)	NC score	0.283532 (rank : 599)
Query Neighborhood Hits	1371	Target Neighborhood Hits	420	Shared Neighborhood Hits	337
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

NEK11_MOUSE
θ value	θ > 10 (rank : 1966)	NC score	0.052536 (rank : 2079)
Query Neighborhood Hits	1371	Target Neighborhood Hits	875	Shared Neighborhood Hits	113
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

NEK1_HUMAN
θ value	θ > 10 (rank : 1967)	NC score	0.061974 (rank : 1853)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1129	Shared Neighborhood Hits	262
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

NEK1_MOUSE
θ value	θ > 10 (rank : 1968)	NC score	0.067585 (rank : 1786)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1311	Shared Neighborhood Hits	310
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

NEK2_HUMAN
θ value	θ > 10 (rank : 1969)	NC score	0.053739 (rank : 2026)
Query Neighborhood Hits	1371	Target Neighborhood Hits	908	Shared Neighborhood Hits	166
SwissProt Accessions	P51955, Q53FD6, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9	Gene names	NEK2, NLK1
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21).

NIP30_HUMAN
θ value	θ > 10 (rank : 1970)	NC score	0.062787 (rank : 1838)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	73
SwissProt Accessions	Q9GZU8	Gene names	NIP30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

NIP30_MOUSE
θ value	θ > 10 (rank : 1971)	NC score	0.056729 (rank : 1952)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	Q91WE2, Q8R0C9	Gene names	Nip30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

NMI_HUMAN
θ value	θ > 10 (rank : 1972)	NC score	0.057239 (rank : 1940)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q13287, Q53TI8, Q9BVE5	Gene names	NMI
Domain Architecture
Description	N-myc-interactor (Nmi) (N-myc and STAT interactor).

NOC3L_HUMAN
θ value	θ > 10 (rank : 1973)	NC score	0.077740 (rank : 1657)
Query Neighborhood Hits	1371	Target Neighborhood Hits	135	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

NOC3L_MOUSE
θ value	θ > 10 (rank : 1974)	NC score	0.109457 (rank : 1382)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	126
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

NOE1_HUMAN
θ value	θ > 10 (rank : 1975)	NC score	0.090314 (rank : 1537)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	204
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

NOE1_MOUSE
θ value	θ > 10 (rank : 1976)	NC score	0.087630 (rank : 1560)
Query Neighborhood Hits	1371	Target Neighborhood Hits	258	Shared Neighborhood Hits	203
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

NOL10_MOUSE
θ value	θ > 10 (rank : 1977)	NC score	0.121081 (rank : 1293)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	123
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NOP14_MOUSE
θ value	θ > 10 (rank : 1978)	NC score	0.149410 (rank : 1097)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	188
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NPHP3_HUMAN
θ value	θ > 10 (rank : 1979)	NC score	0.089944 (rank : 1540)
Query Neighborhood Hits	1371	Target Neighborhood Hits	304	Shared Neighborhood Hits	194
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

NPHP3_MOUSE
θ value	θ > 10 (rank : 1980)	NC score	0.108395 (rank : 1388)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	218
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

NRBF2_HUMAN
θ value	θ > 10 (rank : 1981)	NC score	0.085969 (rank : 1576)
Query Neighborhood Hits	1371	Target Neighborhood Hits	122	Shared Neighborhood Hits	92
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

NRBF2_MOUSE
θ value	θ > 10 (rank : 1982)	NC score	0.054675 (rank : 1994)
Query Neighborhood Hits	1371	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

NRK_HUMAN
θ value	θ > 10 (rank : 1983)	NC score	0.054489 (rank : 1998)
Query Neighborhood Hits	1371	Target Neighborhood Hits	931	Shared Neighborhood Hits	131
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

NRK_MOUSE
θ value	θ > 10 (rank : 1984)	NC score	0.052718 (rank : 2069)
Query Neighborhood Hits	1371	Target Neighborhood Hits	899	Shared Neighborhood Hits	111
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

NSBP1_HUMAN
θ value	θ > 10 (rank : 1985)	NC score	0.089854 (rank : 1541)
Query Neighborhood Hits	1371	Target Neighborhood Hits	251	Shared Neighborhood Hits	100
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NSBP1_MOUSE
θ value	θ > 10 (rank : 1986)	NC score	0.067844 (rank : 1781)
Query Neighborhood Hits	1371	Target Neighborhood Hits	681	Shared Neighborhood Hits	160
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NTBP1_HUMAN
θ value	θ > 10 (rank : 1987)	NC score	0.138626 (rank : 1171)
Query Neighborhood Hits	1371	Target Neighborhood Hits	171	Shared Neighborhood Hits	145
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

NTRK1_HUMAN
θ value	θ > 10 (rank : 1988)	NC score	0.053337 (rank : 2041)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1023	Shared Neighborhood Hits	96
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NU214_HUMAN
θ value	θ > 10 (rank : 1989)	NC score	0.063173 (rank : 1834)
Query Neighborhood Hits	1371	Target Neighborhood Hits	657	Shared Neighborhood Hits	137
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUP54_HUMAN
θ value	θ > 10 (rank : 1990)	NC score	0.068121 (rank : 1776)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z3B4, Q96EA7, Q9NVL5, Q9P0I1	Gene names	NUP54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

NUP54_MOUSE
θ value	θ > 10 (rank : 1991)	NC score	0.080191 (rank : 1633)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BTS4, Q3TSI2, Q8BU42	Gene names	Nup54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

NUP62_HUMAN
θ value	θ > 10 (rank : 1992)	NC score	0.113283 (rank : 1363)
Query Neighborhood Hits	1371	Target Neighborhood Hits	195	Shared Neighborhood Hits	111
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

NUP62_MOUSE
θ value	θ > 10 (rank : 1993)	NC score	0.109285 (rank : 1384)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	117
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

NUPL1_HUMAN
θ value	θ > 10 (rank : 1994)	NC score	0.050738 (rank : 2157)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BVL2, O43160	Gene names	NUPL1, KIAA0410
Domain Architecture	No domain graphic available
Description	Nucleoporin p58/p45 (Nucleoporin-like 1).

OLR1_MOUSE
θ value	θ > 10 (rank : 1995)	NC score	0.285749 (rank : 593)
Query Neighborhood Hits	1371	Target Neighborhood Hits	596	Shared Neighborhood Hits	374
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

OPHN1_MOUSE
θ value	θ > 10 (rank : 1996)	NC score	0.059228 (rank : 1898)
Query Neighborhood Hits	1371	Target Neighborhood Hits	174	Shared Neighborhood Hits	75
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OTU6A_HUMAN
θ value	θ > 10 (rank : 1997)	NC score	0.066234 (rank : 1802)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q7L8S5	Gene names	OTUD6A
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6A.

OTU6B_HUMAN
θ value	θ > 10 (rank : 1998)	NC score	0.133832 (rank : 1200)
Query Neighborhood Hits	1371	Target Neighborhood Hits	182	Shared Neighborhood Hits	155
SwissProt Accessions	Q8N6M0, Q9NTA4, Q9Y387	Gene names	OTUD6B
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

OXR1_HUMAN
θ value	θ > 10 (rank : 1999)	NC score	0.079207 (rank : 1647)
Query Neighborhood Hits	1371	Target Neighborhood Hits	282	Shared Neighborhood Hits	130
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

OXR1_MOUSE
θ value	θ > 10 (rank : 2000)	NC score	0.094874 (rank : 1499)
Query Neighborhood Hits	1371	Target Neighborhood Hits	516	Shared Neighborhood Hits	190
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

OXSR1_HUMAN
θ value	θ > 10 (rank : 2001)	NC score	0.050774 (rank : 2155)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	98
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

OXSR1_MOUSE
θ value	θ > 10 (rank : 2002)	NC score	0.051228 (rank : 2137)
Query Neighborhood Hits	1371	Target Neighborhood Hits	865	Shared Neighborhood Hits	97
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

P3C2A_HUMAN
θ value	θ > 10 (rank : 2003)	NC score	0.061462 (rank : 1859)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	72
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
θ value	θ > 10 (rank : 2004)	NC score	0.060442 (rank : 1873)
Query Neighborhood Hits	1371	Target Neighborhood Hits	181	Shared Neighborhood Hits	72
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2B_HUMAN
θ value	θ > 10 (rank : 2005)	NC score	0.074939 (rank : 1690)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	75
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PALM_HUMAN
θ value	θ > 10 (rank : 2006)	NC score	0.075128 (rank : 1689)
Query Neighborhood Hits	1371	Target Neighborhood Hits	136	Shared Neighborhood Hits	95
SwissProt Accessions	O75781, O43359, O95673, Q92559, Q9UPJ4, Q9UQS2, Q9UQS3	Gene names	PALM, KIAA0270
Domain Architecture
Description	Paralemmin.

PALM_MOUSE
θ value	θ > 10 (rank : 2007)	NC score	0.070444 (rank : 1748)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

PCQAP_HUMAN
θ value	θ > 10 (rank : 2008)	NC score	0.181881 (rank : 913)
Query Neighborhood Hits	1371	Target Neighborhood Hits	549	Shared Neighborhood Hits	223
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 2009)	NC score	0.169620 (rank : 985)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	193
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDCD7_HUMAN
θ value	θ > 10 (rank : 2010)	NC score	0.126631 (rank : 1262)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	141
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PDCD7_MOUSE
θ value	θ > 10 (rank : 2011)	NC score	0.094294 (rank : 1501)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	110
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PELP1_HUMAN
θ value	θ > 10 (rank : 2012)	NC score	0.098617 (rank : 1471)
Query Neighborhood Hits	1371	Target Neighborhood Hits	596	Shared Neighborhood Hits	218
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PERI_HUMAN
θ value	θ > 10 (rank : 2013)	NC score	0.196551 (rank : 856)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	380
SwissProt Accessions	P41219, Q8N577	Gene names	PRPH
Domain Architecture
Description	Peripherin.

PERI_MOUSE
θ value	θ > 10 (rank : 2014)	NC score	0.196437 (rank : 857)
Query Neighborhood Hits	1371	Target Neighborhood Hits	502	Shared Neighborhood Hits	376
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

PERQ1_MOUSE
θ value	θ > 10 (rank : 2015)	NC score	0.084736 (rank : 1586)
Query Neighborhood Hits	1371	Target Neighborhood Hits	215	Shared Neighborhood Hits	120
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

PFD4_HUMAN
θ value	θ > 10 (rank : 2016)	NC score	0.086008 (rank : 1574)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NQP4, Q5TD11, Q92779	Gene names	PFDN4, PFD4
Domain Architecture	No domain graphic available
Description	Prefoldin subunit 4 (Protein C-1).

PFD6_HUMAN
θ value	θ > 10 (rank : 2017)	NC score	0.106011 (rank : 1419)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	99
SwissProt Accessions	O15212	Gene names	PFDN6, HKE2, PFD6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

PFD6_MOUSE
θ value	θ > 10 (rank : 2018)	NC score	0.130955 (rank : 1233)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	120
SwissProt Accessions	Q03958	Gene names	Pfdn6, H2-Ke2, Pfd6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

PHF14_HUMAN
θ value	θ > 10 (rank : 2019)	NC score	0.072873 (rank : 1720)
Query Neighborhood Hits	1371	Target Neighborhood Hits	447	Shared Neighborhood Hits	196
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHLB3_HUMAN
θ value	θ > 10 (rank : 2020)	NC score	0.302321 (rank : 557)
Query Neighborhood Hits	1371	Target Neighborhood Hits	304	Shared Neighborhood Hits	252
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

PKHA5_HUMAN
θ value	θ > 10 (rank : 2021)	NC score	0.165068 (rank : 1011)
Query Neighborhood Hits	1371	Target Neighborhood Hits	455	Shared Neighborhood Hits	225
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	θ > 10 (rank : 2022)	NC score	0.105302 (rank : 1423)
Query Neighborhood Hits	1371	Target Neighborhood Hits	556	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 2023)	NC score	0.124139 (rank : 1273)
Query Neighborhood Hits	1371	Target Neighborhood Hits	591	Shared Neighborhood Hits	213
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHF1_HUMAN
θ value	θ > 10 (rank : 2024)	NC score	0.108337 (rank : 1390)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	θ > 10 (rank : 2025)	NC score	0.106517 (rank : 1413)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	θ > 10 (rank : 2026)	NC score	0.113756 (rank : 1359)
Query Neighborhood Hits	1371	Target Neighborhood Hits	75	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	θ > 10 (rank : 2027)	NC score	0.113078 (rank : 1364)
Query Neighborhood Hits	1371	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHG4_HUMAN
θ value	θ > 10 (rank : 2028)	NC score	0.227017 (rank : 763)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	72
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PKN1_HUMAN
θ value	θ > 10 (rank : 2029)	NC score	0.050253 (rank : 2174)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	116
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

PKN1_MOUSE
θ value	θ > 10 (rank : 2030)	NC score	0.052204 (rank : 2095)
Query Neighborhood Hits	1371	Target Neighborhood Hits	888	Shared Neighborhood Hits	123
SwissProt Accessions	P70268, Q7TST2	Gene names	Pkn1, Pkn, Prk1, Prkcl1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N).

PKN2_HUMAN
θ value	θ > 10 (rank : 2031)	NC score	0.053104 (rank : 2054)
Query Neighborhood Hits	1371	Target Neighborhood Hits	892	Shared Neighborhood Hits	133
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PKN2_MOUSE
θ value	θ > 10 (rank : 2032)	NC score	0.053134 (rank : 2052)
Query Neighborhood Hits	1371	Target Neighborhood Hits	899	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PKN3_MOUSE
θ value	θ > 10 (rank : 2033)	NC score	0.052956 (rank : 2059)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	153
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PLCB3_MOUSE
θ value	θ > 10 (rank : 2034)	NC score	0.163177 (rank : 1021)
Query Neighborhood Hits	1371	Target Neighborhood Hits	344	Shared Neighborhood Hits	251
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCD1_HUMAN
θ value	θ > 10 (rank : 2035)	NC score	0.077426 (rank : 1662)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	63
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	θ > 10 (rank : 2036)	NC score	0.076893 (rank : 1669)
Query Neighborhood Hits	1371	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLVAP_MOUSE
θ value	θ > 10 (rank : 2037)	NC score	0.194406 (rank : 864)
Query Neighborhood Hits	1371	Target Neighborhood Hits	210	Shared Neighborhood Hits	178
SwissProt Accessions	Q91VC4, Q99JB1	Gene names	Plvap, Pv1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (MECA-32 antigen).

POF1B_MOUSE
θ value	θ > 10 (rank : 2038)	NC score	0.365975 (rank : 429)
Query Neighborhood Hits	1371	Target Neighborhood Hits	530	Shared Neighborhood Hits	396
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

PPIG_HUMAN
θ value	θ > 10 (rank : 2039)	NC score	0.121311 (rank : 1290)
Query Neighborhood Hits	1371	Target Neighborhood Hits	670	Shared Neighborhood Hits	281
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

PROX1_HUMAN
θ value	θ > 10 (rank : 2040)	NC score	0.084307 (rank : 1590)
Query Neighborhood Hits	1371	Target Neighborhood Hits	171	Shared Neighborhood Hits	121
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

PROX1_MOUSE
θ value	θ > 10 (rank : 2041)	NC score	0.079613 (rank : 1640)
Query Neighborhood Hits	1371	Target Neighborhood Hits	184	Shared Neighborhood Hits	123
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

PRP40_HUMAN
θ value	θ > 10 (rank : 2042)	NC score	0.121277 (rank : 1292)
Query Neighborhood Hits	1371	Target Neighborhood Hits	442	Shared Neighborhood Hits	206
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	θ > 10 (rank : 2043)	NC score	0.114168 (rank : 1353)
Query Neighborhood Hits	1371	Target Neighborhood Hits	447	Shared Neighborhood Hits	199
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PSIP1_HUMAN
θ value	θ > 10 (rank : 2044)	NC score	0.072508 (rank : 1724)
Query Neighborhood Hits	1371	Target Neighborhood Hits	341	Shared Neighborhood Hits	153
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PSIP1_MOUSE
θ value	θ > 10 (rank : 2045)	NC score	0.070697 (rank : 1746)
Query Neighborhood Hits	1371	Target Neighborhood Hits	313	Shared Neighborhood Hits	128
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

PTMS_HUMAN
θ value	θ > 10 (rank : 2046)	NC score	0.070723 (rank : 1745)
Query Neighborhood Hits	1371	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTN11_HUMAN
θ value	θ > 10 (rank : 2047)	NC score	0.062579 (rank : 1843)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	78
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 2048)	NC score	0.062436 (rank : 1847)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	77
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN23_HUMAN
θ value	θ > 10 (rank : 2049)	NC score	0.053402 (rank : 2038)
Query Neighborhood Hits	1371	Target Neighborhood Hits	646	Shared Neighborhood Hits	195
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 2050)	NC score	0.051140 (rank : 2140)
Query Neighborhood Hits	1371	Target Neighborhood Hits	726	Shared Neighborhood Hits	210
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN6_HUMAN
θ value	θ > 10 (rank : 2051)	NC score	0.052504 (rank : 2082)
Query Neighborhood Hits	1371	Target Neighborhood Hits	234	Shared Neighborhood Hits	79
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 2052)	NC score	0.053204 (rank : 2048)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	74
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTRF_HUMAN
θ value	θ > 10 (rank : 2053)	NC score	0.120381 (rank : 1298)
Query Neighborhood Hits	1371	Target Neighborhood Hits	153	Shared Neighborhood Hits	118
SwissProt Accessions	Q6NZI2, O00535, Q6GMY1, Q96H74, Q9BT85, Q9HAP4	Gene names	PTRF
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor (PTRF protein).

PTRF_MOUSE
θ value	θ > 10 (rank : 2054)	NC score	0.107238 (rank : 1404)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	117
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

RAB3I_HUMAN
θ value	θ > 10 (rank : 2055)	NC score	0.158377 (rank : 1049)
Query Neighborhood Hits	1371	Target Neighborhood Hits	270	Shared Neighborhood Hits	221
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

RABE2_HUMAN
θ value	θ > 10 (rank : 2056)	NC score	0.364836 (rank : 434)
Query Neighborhood Hits	1371	Target Neighborhood Hits	545	Shared Neighborhood Hits	411
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAF1_HUMAN
θ value	θ > 10 (rank : 2057)	NC score	0.060126 (rank : 1884)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	111
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 2058)	NC score	0.060416 (rank : 1875)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	111
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RASA2_HUMAN
θ value	θ > 10 (rank : 2059)	NC score	0.088777 (rank : 1553)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_MOUSE
θ value	θ > 10 (rank : 2060)	NC score	0.092764 (rank : 1518)
Query Neighborhood Hits	1371	Target Neighborhood Hits	159	Shared Neighborhood Hits	82
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA3_HUMAN
θ value	θ > 10 (rank : 2061)	NC score	0.089558 (rank : 1543)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	89
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 2062)	NC score	0.078988 (rank : 1649)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	78
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RASF7_HUMAN
θ value	θ > 10 (rank : 2063)	NC score	0.063653 (rank : 1827)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	54
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

RBBP6_HUMAN
θ value	θ > 10 (rank : 2064)	NC score	0.104157 (rank : 1430)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1135	Shared Neighborhood Hits	267
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 2065)	NC score	0.083786 (rank : 1600)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1014	Shared Neighborhood Hits	230
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBNS5_HUMAN
θ value	θ > 10 (rank : 2066)	NC score	0.101189 (rank : 1453)
Query Neighborhood Hits	1371	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	θ > 10 (rank : 2067)	NC score	0.119137 (rank : 1310)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	149
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

RBP1_HUMAN
θ value	θ > 10 (rank : 2068)	NC score	0.242349 (rank : 720)
Query Neighborhood Hits	1371	Target Neighborhood Hits	521	Shared Neighborhood Hits	370
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_MOUSE
θ value	θ > 10 (rank : 2069)	NC score	0.225125 (rank : 770)
Query Neighborhood Hits	1371	Target Neighborhood Hits	493	Shared Neighborhood Hits	344
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

REN3A_HUMAN
θ value	θ > 10 (rank : 2070)	NC score	0.153973 (rank : 1078)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

RET_HUMAN
θ value	θ > 10 (rank : 2071)	NC score	0.051936 (rank : 2106)
Query Neighborhood Hits	1371	Target Neighborhood Hits	873	Shared Neighborhood Hits	96
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 2072)	NC score	0.051241 (rank : 2135)
Query Neighborhood Hits	1371	Target Neighborhood Hits	884	Shared Neighborhood Hits	95
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RFC1_MOUSE
θ value	θ > 10 (rank : 2073)	NC score	0.062385 (rank : 1848)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	115
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RGAP1_HUMAN
θ value	θ > 10 (rank : 2074)	NC score	0.074671 (rank : 1696)
Query Neighborhood Hits	1371	Target Neighborhood Hits	189	Shared Neighborhood Hits	101
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGS3_HUMAN
θ value	θ > 10 (rank : 2075)	NC score	0.060774 (rank : 1866)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1375	Shared Neighborhood Hits	203
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RHG05_MOUSE
θ value	θ > 10 (rank : 2076)	NC score	0.050352 (rank : 2169)
Query Neighborhood Hits	1371	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG12_HUMAN
θ value	θ > 10 (rank : 2077)	NC score	0.073905 (rank : 1704)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	θ > 10 (rank : 2078)	NC score	0.076436 (rank : 1671)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	90
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG25_MOUSE
θ value	θ > 10 (rank : 2079)	NC score	0.132090 (rank : 1218)
Query Neighborhood Hits	1371	Target Neighborhood Hits	492	Shared Neighborhood Hits	234
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RIF1_HUMAN
θ value	θ > 10 (rank : 2080)	NC score	0.082939 (rank : 1610)
Query Neighborhood Hits	1371	Target Neighborhood Hits	320	Shared Neighborhood Hits	146
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

RILP_HUMAN
θ value	θ > 10 (rank : 2081)	NC score	0.151013 (rank : 1091)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	160
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

RILP_MOUSE
θ value	θ > 10 (rank : 2082)	NC score	0.210020 (rank : 822)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	205
SwissProt Accessions	Q5ND29, Q80WB8, Q8CHY9	Gene names	Rilp
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

RIMS3_HUMAN
θ value	θ > 10 (rank : 2083)	NC score	0.062692 (rank : 1841)
Query Neighborhood Hits	1371	Target Neighborhood Hits	66	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	θ > 10 (rank : 2084)	NC score	0.060218 (rank : 1880)
Query Neighborhood Hits	1371	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS4_HUMAN
θ value	θ > 10 (rank : 2085)	NC score	0.069765 (rank : 1758)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_MOUSE
θ value	θ > 10 (rank : 2086)	NC score	0.070172 (rank : 1750)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIPK1_HUMAN
θ value	θ > 10 (rank : 2087)	NC score	0.052375 (rank : 2084)
Query Neighborhood Hits	1371	Target Neighborhood Hits	891	Shared Neighborhood Hits	99
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
θ value	θ > 10 (rank : 2088)	NC score	0.053347 (rank : 2040)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	98
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK2_HUMAN
θ value	θ > 10 (rank : 2089)	NC score	0.054356 (rank : 2007)
Query Neighborhood Hits	1371	Target Neighborhood Hits	774	Shared Neighborhood Hits	91
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 2090)	NC score	0.053733 (rank : 2027)
Query Neighborhood Hits	1371	Target Neighborhood Hits	776	Shared Neighborhood Hits	91
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK4_HUMAN
θ value	θ > 10 (rank : 2091)	NC score	0.054223 (rank : 2013)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1094	Shared Neighborhood Hits	127
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

RIPK5_MOUSE
θ value	θ > 10 (rank : 2092)	NC score	0.053984 (rank : 2018)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	118
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

RLP24_MOUSE
θ value	θ > 10 (rank : 2093)	NC score	0.054419 (rank : 2003)
Query Neighborhood Hits	1371	Target Neighborhood Hits	65	Shared Neighborhood Hits	52
SwissProt Accessions	Q99L28	Gene names
Domain Architecture	No domain graphic available
Description	Probable ribosome biogenesis protein RLP24.

RN168_MOUSE
θ value	θ > 10 (rank : 2094)	NC score	0.107602 (rank : 1401)
Query Neighborhood Hits	1371	Target Neighborhood Hits	440	Shared Neighborhood Hits	178
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF17_MOUSE
θ value	θ > 10 (rank : 2095)	NC score	0.051382 (rank : 2130)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

RNF8_HUMAN
θ value	θ > 10 (rank : 2096)	NC score	0.212896 (rank : 809)
Query Neighborhood Hits	1371	Target Neighborhood Hits	622	Shared Neighborhood Hits	306
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 2097)	NC score	0.189522 (rank : 880)
Query Neighborhood Hits	1371	Target Neighborhood Hits	618	Shared Neighborhood Hits	316
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RON_HUMAN
θ value	θ > 10 (rank : 2098)	NC score	0.053651 (rank : 2031)
Query Neighborhood Hits	1371	Target Neighborhood Hits	842	Shared Neighborhood Hits	94
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 2099)	NC score	0.053486 (rank : 2037)
Query Neighborhood Hits	1371	Target Neighborhood Hits	836	Shared Neighborhood Hits	95
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 2100)	NC score	0.050357 (rank : 2168)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1018	Shared Neighborhood Hits	95
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 2101)	NC score	0.050802 (rank : 2153)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1025	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_MOUSE
θ value	θ > 10 (rank : 2102)	NC score	0.050316 (rank : 2171)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1000	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

ROS_HUMAN
θ value	θ > 10 (rank : 2103)	NC score	0.058539 (rank : 1911)
Query Neighborhood Hits	1371	Target Neighborhood Hits	907	Shared Neighborhood Hits	97
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RP1L1_HUMAN
θ value	θ > 10 (rank : 2104)	NC score	0.125344 (rank : 1268)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1072	Shared Neighborhood Hits	253
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RSF1_HUMAN
θ value	θ > 10 (rank : 2105)	NC score	0.132121 (rank : 1217)
Query Neighborhood Hits	1371	Target Neighborhood Hits	539	Shared Neighborhood Hits	220
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RT26_HUMAN
θ value	θ > 10 (rank : 2106)	NC score	0.116510 (rank : 1329)
Query Neighborhood Hits	1371	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYN8, Q96Q58	Gene names	MRPS26, RPMS13
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S26, mitochondrial precursor (MRP-S26) (MRP- S13).

RYK_HUMAN
θ value	θ > 10 (rank : 2107)	NC score	0.051300 (rank : 2133)
Query Neighborhood Hits	1371	Target Neighborhood Hits	701	Shared Neighborhood Hits	77
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 2108)	NC score	0.051088 (rank : 2142)
Query Neighborhood Hits	1371	Target Neighborhood Hits	715	Shared Neighborhood Hits	79
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

S6OS1_HUMAN
θ value	θ > 10 (rank : 2109)	NC score	0.097014 (rank : 1481)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N1H7	Gene names	SIX6OS1, C14orf39
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

S6OS1_MOUSE
θ value	θ > 10 (rank : 2110)	NC score	0.071058 (rank : 1740)
Query Neighborhood Hits	1371	Target Neighborhood Hits	105	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CTN5, Q9D5F5, Q9D5Y9	Gene names	Six6os1
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

SAFB2_MOUSE
θ value	θ > 10 (rank : 2111)	NC score	0.236947 (rank : 735)
Query Neighborhood Hits	1371	Target Neighborhood Hits	581	Shared Neighborhood Hits	348
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SAKS1_HUMAN
θ value	θ > 10 (rank : 2112)	NC score	0.106923 (rank : 1409)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	136
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

SAKS1_MOUSE
θ value	θ > 10 (rank : 2113)	NC score	0.116078 (rank : 1332)
Query Neighborhood Hits	1371	Target Neighborhood Hits	208	Shared Neighborhood Hits	148
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

SAMN1_HUMAN
θ value	θ > 10 (rank : 2114)	NC score	0.066977 (rank : 1795)
Query Neighborhood Hits	1371	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

SAMN1_MOUSE
θ value	θ > 10 (rank : 2115)	NC score	0.062011 (rank : 1852)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	45
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

SCG2_HUMAN
θ value	θ > 10 (rank : 2116)	NC score	0.056251 (rank : 1962)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	88
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

SCG3_MOUSE
θ value	θ > 10 (rank : 2117)	NC score	0.086944 (rank : 1567)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	110
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

SDCG1_HUMAN
θ value	θ > 10 (rank : 2118)	NC score	0.072537 (rank : 1723)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	103
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

SDPR_MOUSE
θ value	θ > 10 (rank : 2119)	NC score	0.219564 (rank : 788)
Query Neighborhood Hits	1371	Target Neighborhood Hits	485	Shared Neighborhood Hits	273
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SDS3_HUMAN
θ value	θ > 10 (rank : 2120)	NC score	0.186953 (rank : 890)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	196
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SDS3_MOUSE
θ value	θ > 10 (rank : 2121)	NC score	0.178339 (rank : 934)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	186
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SEC20_HUMAN
θ value	θ > 10 (rank : 2122)	NC score	0.165909 (rank : 1003)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	169
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

SEC20_MOUSE
θ value	θ > 10 (rank : 2123)	NC score	0.259423 (rank : 659)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	264
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

SEC63_MOUSE
θ value	θ > 10 (rank : 2124)	NC score	0.055372 (rank : 1977)
Query Neighborhood Hits	1371	Target Neighborhood Hits	601	Shared Neighborhood Hits	169
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEMG2_HUMAN
θ value	θ > 10 (rank : 2125)	NC score	0.059909 (rank : 1888)
Query Neighborhood Hits	1371	Target Neighborhood Hits	251	Shared Neighborhood Hits	86
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SEPT8_HUMAN
θ value	θ > 10 (rank : 2126)	NC score	0.093245 (rank : 1511)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	217
SwissProt Accessions	Q92599, Q8IX36, Q8IX37, Q9BVB3	Gene names	SEPT8, KIAA0202
Domain Architecture
Description	Septin-8.

SEPT8_MOUSE
θ value	θ > 10 (rank : 2127)	NC score	0.080073 (rank : 1635)
Query Neighborhood Hits	1371	Target Neighborhood Hits	251	Shared Neighborhood Hits	183
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

SF3B2_HUMAN
θ value	θ > 10 (rank : 2128)	NC score	0.052348 (rank : 2085)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

SFR11_HUMAN
θ value	θ > 10 (rank : 2129)	NC score	0.067901 (rank : 1780)
Query Neighborhood Hits	1371	Target Neighborhood Hits	246	Shared Neighborhood Hits	95
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFR12_HUMAN
θ value	θ > 10 (rank : 2130)	NC score	0.237487 (rank : 734)
Query Neighborhood Hits	1371	Target Neighborhood Hits	553	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFR12_MOUSE
θ value	θ > 10 (rank : 2131)	NC score	0.180352 (rank : 923)
Query Neighborhood Hits	1371	Target Neighborhood Hits	486	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SFR16_MOUSE
θ value	θ > 10 (rank : 2132)	NC score	0.053151 (rank : 2051)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CFC7, Q8CFC8, Q9Z2N3	Gene names	Sfrs16, Clasp, Swap2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2) (Clk4-associating SR-related protein).

SGOL2_HUMAN
θ value	θ > 10 (rank : 2133)	NC score	0.127398 (rank : 1257)
Query Neighborhood Hits	1371	Target Neighborhood Hits	207	Shared Neighborhood Hits	122
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

SH21A_HUMAN
θ value	θ > 10 (rank : 2134)	NC score	0.077542 (rank : 1660)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 2135)	NC score	0.079554 (rank : 1641)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 2136)	NC score	0.096202 (rank : 1486)
Query Neighborhood Hits	1371	Target Neighborhood Hits	101	Shared Neighborhood Hits	51
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 2137)	NC score	0.102070 (rank : 1445)
Query Neighborhood Hits	1371	Target Neighborhood Hits	101	Shared Neighborhood Hits	50
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH22A_HUMAN
θ value	θ > 10 (rank : 2138)	NC score	0.055859 (rank : 1970)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SH22A_MOUSE
θ value	θ > 10 (rank : 2139)	NC score	0.062537 (rank : 1845)
Query Neighborhood Hits	1371	Target Neighborhood Hits	179	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH2D3_HUMAN
θ value	θ > 10 (rank : 2140)	NC score	0.056608 (rank : 1956)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SH2D3_MOUSE
θ value	θ > 10 (rank : 2141)	NC score	0.061478 (rank : 1857)
Query Neighborhood Hits	1371	Target Neighborhood Hits	174	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SHB_HUMAN
θ value	θ > 10 (rank : 2142)	NC score	0.086638 (rank : 1571)
Query Neighborhood Hits	1371	Target Neighborhood Hits	141	Shared Neighborhood Hits	68
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHB_MOUSE
θ value	θ > 10 (rank : 2143)	NC score	0.088299 (rank : 1557)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC1_HUMAN
θ value	θ > 10 (rank : 2144)	NC score	0.083412 (rank : 1604)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	69
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	θ > 10 (rank : 2145)	NC score	0.082828 (rank : 1612)
Query Neighborhood Hits	1371	Target Neighborhood Hits	180	Shared Neighborhood Hits	69
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 2146)	NC score	0.081471 (rank : 1622)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	66
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 2147)	NC score	0.077936 (rank : 1656)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 2148)	NC score	0.080208 (rank : 1632)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	62
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 2149)	NC score	0.085434 (rank : 1582)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	66
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHD_HUMAN
θ value	θ > 10 (rank : 2150)	NC score	0.082691 (rank : 1613)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	70
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHD_MOUSE
θ value	θ > 10 (rank : 2151)	NC score	0.084009 (rank : 1596)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	67
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_HUMAN
θ value	θ > 10 (rank : 2152)	NC score	0.091461 (rank : 1530)
Query Neighborhood Hits	1371	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHE_MOUSE
θ value	θ > 10 (rank : 2153)	NC score	0.095310 (rank : 1494)
Query Neighborhood Hits	1371	Target Neighborhood Hits	169	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SKIL_HUMAN
θ value	θ > 10 (rank : 2154)	NC score	0.282963 (rank : 601)
Query Neighborhood Hits	1371	Target Neighborhood Hits	460	Shared Neighborhood Hits	355
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SLAP1_HUMAN
θ value	θ > 10 (rank : 2155)	NC score	0.157692 (rank : 1055)
Query Neighborhood Hits	1371	Target Neighborhood Hits	113	Shared Neighborhood Hits	64
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 2156)	NC score	0.156198 (rank : 1064)
Query Neighborhood Hits	1371	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SMCA2_HUMAN
θ value	θ > 10 (rank : 2157)	NC score	0.051789 (rank : 2111)
Query Neighborhood Hits	1371	Target Neighborhood Hits	503	Shared Neighborhood Hits	175
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	θ > 10 (rank : 2158)	NC score	0.058469 (rank : 1912)
Query Neighborhood Hits	1371	Target Neighborhood Hits	597	Shared Neighborhood Hits	201
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMG1_HUMAN
θ value	θ > 10 (rank : 2159)	NC score	0.057562 (rank : 1937)
Query Neighborhood Hits	1371	Target Neighborhood Hits	231	Shared Neighborhood Hits	121
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SMRC1_MOUSE
θ value	θ > 10 (rank : 2160)	NC score	0.052333 (rank : 2086)
Query Neighborhood Hits	1371	Target Neighborhood Hits	459	Shared Neighborhood Hits	155
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SNIP_HUMAN
θ value	θ > 10 (rank : 2161)	NC score	0.091074 (rank : 1532)
Query Neighborhood Hits	1371	Target Neighborhood Hits	313	Shared Neighborhood Hits	156
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SNIP_MOUSE
θ value	θ > 10 (rank : 2162)	NC score	0.072906 (rank : 1719)
Query Neighborhood Hits	1371	Target Neighborhood Hits	319	Shared Neighborhood Hits	138
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SNP25_HUMAN
θ value	θ > 10 (rank : 2163)	NC score	0.071668 (rank : 1736)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	P60880, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	SNAP25, SNAP
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

SNP25_MOUSE
θ value	θ > 10 (rank : 2164)	NC score	0.071668 (rank : 1737)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	P60879, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	Snap25, Snap
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

SNPH_HUMAN
θ value	θ > 10 (rank : 2165)	NC score	0.158734 (rank : 1045)
Query Neighborhood Hits	1371	Target Neighborhood Hits	236	Shared Neighborhood Hits	166
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

SNUT1_MOUSE
θ value	θ > 10 (rank : 2166)	NC score	0.055385 (rank : 1976)
Query Neighborhood Hits	1371	Target Neighborhood Hits	159	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z315, Q8K155, Q9R1I9, Q9R270	Gene names	Sart1, Haf
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 1 (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (mSART-1) (Hypoxia- associated factor).

SNW1_HUMAN
θ value	θ > 10 (rank : 2167)	NC score	0.050342 (rank : 2170)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

SNW1_MOUSE
θ value	θ > 10 (rank : 2168)	NC score	0.050395 (rank : 2167)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

SNX9_MOUSE
θ value	θ > 10 (rank : 2169)	NC score	0.131281 (rank : 1229)
Query Neighborhood Hits	1371	Target Neighborhood Hits	141	Shared Neighborhood Hits	99
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

SOCS6_MOUSE
θ value	θ > 10 (rank : 2170)	NC score	0.050677 (rank : 2161)
Query Neighborhood Hits	1371	Target Neighborhood Hits	146	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

SOCS7_MOUSE
θ value	θ > 10 (rank : 2171)	NC score	0.062986 (rank : 1835)
Query Neighborhood Hits	1371	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SOS1_HUMAN
θ value	θ > 10 (rank : 2172)	NC score	0.139886 (rank : 1163)
Query Neighborhood Hits	1371	Target Neighborhood Hits	274	Shared Neighborhood Hits	71
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	θ > 10 (rank : 2173)	NC score	0.134493 (rank : 1194)
Query Neighborhood Hits	1371	Target Neighborhood Hits	281	Shared Neighborhood Hits	76
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS2_HUMAN
θ value	θ > 10 (rank : 2174)	NC score	0.110394 (rank : 1376)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	54
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SOX6_HUMAN
θ value	θ > 10 (rank : 2175)	NC score	0.057696 (rank : 1933)
Query Neighborhood Hits	1371	Target Neighborhood Hits	332	Shared Neighborhood Hits	143
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
θ value	θ > 10 (rank : 2176)	NC score	0.057669 (rank : 1934)
Query Neighborhood Hits	1371	Target Neighborhood Hits	341	Shared Neighborhood Hits	143
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SPC24_HUMAN
θ value	θ > 10 (rank : 2177)	NC score	0.234097 (rank : 742)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	261
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

SPC24_MOUSE
θ value	θ > 10 (rank : 2178)	NC score	0.108392 (rank : 1389)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D083, Q3TIF5, Q8CD13	Gene names	Spbc24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24.

SPTB1_HUMAN
θ value	θ > 10 (rank : 2179)	NC score	0.214021 (rank : 807)
Query Neighborhood Hits	1371	Target Neighborhood Hits	541	Shared Neighborhood Hits	380
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB1_MOUSE
θ value	θ > 10 (rank : 2180)	NC score	0.232343 (rank : 748)
Query Neighborhood Hits	1371	Target Neighborhood Hits	543	Shared Neighborhood Hits	376
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTN2_HUMAN
θ value	θ > 10 (rank : 2181)	NC score	0.172092 (rank : 972)
Query Neighborhood Hits	1371	Target Neighborhood Hits	535	Shared Neighborhood Hits	334
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SPTN4_HUMAN
θ value	θ > 10 (rank : 2182)	NC score	0.185086 (rank : 900)
Query Neighborhood Hits	1371	Target Neighborhood Hits	570	Shared Neighborhood Hits	347
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

SPTN5_HUMAN
θ value	θ > 10 (rank : 2183)	NC score	0.212934 (rank : 808)
Query Neighborhood Hits	1371	Target Neighborhood Hits	674	Shared Neighborhood Hits	416
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SRCA_HUMAN
θ value	θ > 10 (rank : 2184)	NC score	0.098465 (rank : 1473)
Query Neighborhood Hits	1371	Target Neighborhood Hits	380	Shared Neighborhood Hits	65
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRCA_MOUSE
θ value	θ > 10 (rank : 2185)	NC score	0.100357 (rank : 1460)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRMS_HUMAN
θ value	θ > 10 (rank : 2186)	NC score	0.086796 (rank : 1569)
Query Neighborhood Hits	1371	Target Neighborhood Hits	946	Shared Neighborhood Hits	152
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRPK2_MOUSE
θ value	θ > 10 (rank : 2187)	NC score	0.053591 (rank : 2035)
Query Neighborhood Hits	1371	Target Neighborhood Hits	765	Shared Neighborhood Hits	188
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

SRRM1_MOUSE
θ value	θ > 10 (rank : 2188)	NC score	0.055549 (rank : 1973)
Query Neighborhood Hits	1371	Target Neighborhood Hits	966	Shared Neighborhood Hits	164
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 2189)	NC score	0.056570 (rank : 1958)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1296	Shared Neighborhood Hits	181
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 2190)	NC score	0.051886 (rank : 2109)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1470	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SSNA1_HUMAN
θ value	θ > 10 (rank : 2191)	NC score	0.153047 (rank : 1080)
Query Neighborhood Hits	1371	Target Neighborhood Hits	175	Shared Neighborhood Hits	141
SwissProt Accessions	O43805, Q6FG70, Q9BVW8	Gene names	SSNA1, NA14
Domain Architecture
Description	Sjoegren syndrome nuclear autoantigen 1 (Nuclear autoantigen of 14 kDa).

SSNA1_MOUSE
θ value	θ > 10 (rank : 2192)	NC score	0.159025 (rank : 1042)
Query Neighborhood Hits	1371	Target Neighborhood Hits	182	Shared Neighborhood Hits	149
SwissProt Accessions	Q9JJ94	Gene names	Ssna1
Domain Architecture	No domain graphic available
Description	Sjoegren syndrome nuclear autoantigen 1 homolog.

ST18_HUMAN
θ value	θ > 10 (rank : 2193)	NC score	0.078573 (rank : 1654)
Query Neighborhood Hits	1371	Target Neighborhood Hits	252	Shared Neighborhood Hits	166
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

ST18_MOUSE
θ value	θ > 10 (rank : 2194)	NC score	0.072122 (rank : 1728)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	159
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

STK24_HUMAN
θ value	θ > 10 (rank : 2195)	NC score	0.052542 (rank : 2078)
Query Neighborhood Hits	1371	Target Neighborhood Hits	853	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

STK24_MOUSE
θ value	θ > 10 (rank : 2196)	NC score	0.053241 (rank : 2045)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	98
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

STK25_HUMAN
θ value	θ > 10 (rank : 2197)	NC score	0.052589 (rank : 2075)
Query Neighborhood Hits	1371	Target Neighborhood Hits	853	Shared Neighborhood Hits	94
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

STK25_MOUSE
θ value	θ > 10 (rank : 2198)	NC score	0.052802 (rank : 2064)
Query Neighborhood Hits	1371	Target Neighborhood Hits	851	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

STK31_HUMAN
θ value	θ > 10 (rank : 2199)	NC score	0.110912 (rank : 1373)
Query Neighborhood Hits	1371	Target Neighborhood Hits	570	Shared Neighborhood Hits	193
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

STK31_MOUSE
θ value	θ > 10 (rank : 2200)	NC score	0.108303 (rank : 1391)
Query Neighborhood Hits	1371	Target Neighborhood Hits	474	Shared Neighborhood Hits	167
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

STK39_HUMAN
θ value	θ > 10 (rank : 2201)	NC score	0.052052 (rank : 2100)
Query Neighborhood Hits	1371	Target Neighborhood Hits	882	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK39_MOUSE
θ value	θ > 10 (rank : 2202)	NC score	0.052300 (rank : 2090)
Query Neighborhood Hits	1371	Target Neighborhood Hits	915	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

STX12_HUMAN
θ value	θ > 10 (rank : 2203)	NC score	0.128604 (rank : 1248)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	172
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

STX12_MOUSE
θ value	θ > 10 (rank : 2204)	NC score	0.171855 (rank : 974)
Query Neighborhood Hits	1371	Target Neighborhood Hits	283	Shared Neighborhood Hits	220
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

STX18_HUMAN
θ value	θ > 10 (rank : 2205)	NC score	0.096775 (rank : 1483)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	127
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

STX1A_HUMAN
θ value	θ > 10 (rank : 2206)	NC score	0.103699 (rank : 1432)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	196
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX1A_MOUSE
θ value	θ > 10 (rank : 2207)	NC score	0.102865 (rank : 1438)
Query Neighborhood Hits	1371	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX1B_HUMAN
θ value	θ > 10 (rank : 2208)	NC score	0.111897 (rank : 1369)
Query Neighborhood Hits	1371	Target Neighborhood Hits	252	Shared Neighborhood Hits	183
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

STX1C_HUMAN
θ value	θ > 10 (rank : 2209)	NC score	0.142415 (rank : 1146)
Query Neighborhood Hits	1371	Target Neighborhood Hits	270	Shared Neighborhood Hits	215
SwissProt Accessions	P61266	Gene names	STX1B2
Domain Architecture
Description	Syntaxin-1B2.

STX1C_MOUSE
θ value	θ > 10 (rank : 2210)	NC score	0.142415 (rank : 1147)
Query Neighborhood Hits	1371	Target Neighborhood Hits	270	Shared Neighborhood Hits	215
SwissProt Accessions	P61264, P32853	Gene names	Stx1b2, Stx1b
Domain Architecture
Description	Syntaxin-1B2 (Syntaxin 1B).

STX2_HUMAN
θ value	θ > 10 (rank : 2211)	NC score	0.067065 (rank : 1793)
Query Neighborhood Hits	1371	Target Neighborhood Hits	158	Shared Neighborhood Hits	119
SwissProt Accessions	P32856, Q86VW8	Gene names	STX2, EPIM
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

STX4_HUMAN
θ value	θ > 10 (rank : 2212)	NC score	0.163217 (rank : 1020)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	210
SwissProt Accessions	Q12846, Q15525	Gene names	STX4, STX4A
Domain Architecture
Description	Syntaxin-4 (NY-REN-31 antigen).

STX4_MOUSE
θ value	θ > 10 (rank : 2213)	NC score	0.176221 (rank : 944)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	242
SwissProt Accessions	P70452	Gene names	Stx4, Stx4a
Domain Architecture
Description	Syntaxin-4.

STX5_HUMAN
θ value	θ > 10 (rank : 2214)	NC score	0.058210 (rank : 1921)
Query Neighborhood Hits	1371	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	Q13190, Q5U0D4, Q7Z3T6, Q9BUG1	Gene names	STX5, STX5A
Domain Architecture
Description	Syntaxin-5.

STX5_MOUSE
θ value	θ > 10 (rank : 2215)	NC score	0.051173 (rank : 2139)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K1E0, Q3TM79, Q99J28, Q9JKP2	Gene names	Stx5, Stx5a
Domain Architecture
Description	Syntaxin-5.

STX7_MOUSE
θ value	θ > 10 (rank : 2216)	NC score	0.051988 (rank : 2102)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	82
SwissProt Accessions	O70439	Gene names	Stx7, Syn7
Domain Architecture
Description	Syntaxin-7.

STXB4_MOUSE
θ value	θ > 10 (rank : 2217)	NC score	0.268972 (rank : 638)
Query Neighborhood Hits	1371	Target Neighborhood Hits	629	Shared Neighborhood Hits	394
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STYK1_HUMAN
θ value	θ > 10 (rank : 2218)	NC score	0.064019 (rank : 1822)
Query Neighborhood Hits	1371	Target Neighborhood Hits	786	Shared Neighborhood Hits	94
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 2219)	NC score	0.065081 (rank : 1813)
Query Neighborhood Hits	1371	Target Neighborhood Hits	779	Shared Neighborhood Hits	92
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

SURF6_HUMAN
θ value	θ > 10 (rank : 2220)	NC score	0.087521 (rank : 1562)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	71
SwissProt Accessions	O75683, Q9BRK9, Q9BTZ5, Q9UK24	Gene names	SURF6, SURF-6
Domain Architecture
Description	Surfeit locus protein 6.

SURF6_MOUSE
θ value	θ > 10 (rank : 2221)	NC score	0.191372 (rank : 876)
Query Neighborhood Hits	1371	Target Neighborhood Hits	195	Shared Neighborhood Hits	156
SwissProt Accessions	P70279, Q8BPI4, Q8BRL7, Q8R0Q7	Gene names	Surf6, Surf-6
Domain Architecture
Description	Surfeit locus protein 6.

SYBU_HUMAN
θ value	θ > 10 (rank : 2222)	NC score	0.119469 (rank : 1308)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

SYBU_MOUSE
θ value	θ > 10 (rank : 2223)	NC score	0.133137 (rank : 1209)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	142
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

SYCP2_HUMAN
θ value	θ > 10 (rank : 2224)	NC score	0.091298 (rank : 1531)
Query Neighborhood Hits	1371	Target Neighborhood Hits	230	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

SYCP3_HUMAN
θ value	θ > 10 (rank : 2225)	NC score	0.182173 (rank : 912)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	216
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

SYCP3_MOUSE
θ value	θ > 10 (rank : 2226)	NC score	0.107176 (rank : 1406)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	118
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

SYT12_HUMAN
θ value	θ > 10 (rank : 2227)	NC score	0.115621 (rank : 1335)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
θ value	θ > 10 (rank : 2228)	NC score	0.117228 (rank : 1322)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT13_HUMAN
θ value	θ > 10 (rank : 2229)	NC score	0.102187 (rank : 1442)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	55
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
θ value	θ > 10 (rank : 2230)	NC score	0.099839 (rank : 1465)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_HUMAN
θ value	θ > 10 (rank : 2231)	NC score	0.093620 (rank : 1508)
Query Neighborhood Hits	1371	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_MOUSE
θ value	θ > 10 (rank : 2232)	NC score	0.095988 (rank : 1488)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT15_HUMAN
θ value	θ > 10 (rank : 2233)	NC score	0.118750 (rank : 1312)
Query Neighborhood Hits	1371	Target Neighborhood Hits	112	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT15_MOUSE
θ value	θ > 10 (rank : 2234)	NC score	0.112624 (rank : 1366)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYT8_MOUSE
θ value	θ > 10 (rank : 2235)	NC score	0.127509 (rank : 1255)
Query Neighborhood Hits	1371	Target Neighborhood Hits	94	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYTL2_HUMAN
θ value	θ > 10 (rank : 2236)	NC score	0.133303 (rank : 1208)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL3_MOUSE
θ value	θ > 10 (rank : 2237)	NC score	0.112554 (rank : 1367)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYTL5_MOUSE
θ value	θ > 10 (rank : 2238)	NC score	0.137817 (rank : 1178)
Query Neighborhood Hits	1371	Target Neighborhood Hits	154	Shared Neighborhood Hits	79
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

T2_MOUSE
θ value	θ > 10 (rank : 2239)	NC score	0.205087 (rank : 831)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	101
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

TACC1_HUMAN
θ value	θ > 10 (rank : 2240)	NC score	0.321593 (rank : 513)
Query Neighborhood Hits	1371	Target Neighborhood Hits	597	Shared Neighborhood Hits	424
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC2_HUMAN
θ value	θ > 10 (rank : 2241)	NC score	0.339367 (rank : 485)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	477
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 2242)	NC score	0.303456 (rank : 553)
Query Neighborhood Hits	1371	Target Neighborhood Hits	774	Shared Neighborhood Hits	427
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TACC3_HUMAN
θ value	θ > 10 (rank : 2243)	NC score	0.297330 (rank : 574)
Query Neighborhood Hits	1371	Target Neighborhood Hits	779	Shared Neighborhood Hits	421
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TAD3L_HUMAN
θ value	θ > 10 (rank : 2244)	NC score	0.072292 (rank : 1726)
Query Neighborhood Hits	1371	Target Neighborhood Hits	189	Shared Neighborhood Hits	115
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

TAD3L_MOUSE
θ value	θ > 10 (rank : 2245)	NC score	0.070955 (rank : 1742)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	114
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TAF3_HUMAN
θ value	θ > 10 (rank : 2246)	NC score	0.138832 (rank : 1170)
Query Neighborhood Hits	1371	Target Neighborhood Hits	568	Shared Neighborhood Hits	234
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 2247)	NC score	0.145768 (rank : 1126)
Query Neighborhood Hits	1371	Target Neighborhood Hits	463	Shared Neighborhood Hits	218
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF7_HUMAN
θ value	θ > 10 (rank : 2248)	NC score	0.187172 (rank : 889)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	186
SwissProt Accessions	Q15545, Q13036	Gene names	TAF7, TAF2F, TAFII55
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TAF7_MOUSE
θ value	θ > 10 (rank : 2249)	NC score	0.174304 (rank : 959)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	183
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TAK1L_HUMAN
θ value	θ > 10 (rank : 2250)	NC score	0.064389 (rank : 1819)
Query Neighborhood Hits	1371	Target Neighborhood Hits	141	Shared Neighborhood Hits	97
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

TAK1L_MOUSE
θ value	θ > 10 (rank : 2251)	NC score	0.073634 (rank : 1707)
Query Neighborhood Hits	1371	Target Neighborhood Hits	106	Shared Neighborhood Hits	88
SwissProt Accessions	P58500	Gene names	Tak1l, ORF63
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

TANK_MOUSE
θ value	θ > 10 (rank : 2252)	NC score	0.052752 (rank : 2066)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	62
SwissProt Accessions	P70347, Q61178	Gene names	Tank, Itraf
Domain Architecture
Description	TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF).

TBCD1_HUMAN
θ value	θ > 10 (rank : 2253)	NC score	0.080365 (rank : 1630)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	168
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TBCD1_MOUSE
θ value	θ > 10 (rank : 2254)	NC score	0.075506 (rank : 1683)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	154
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

TBCD2_HUMAN
θ value	θ > 10 (rank : 2255)	NC score	0.150872 (rank : 1092)
Query Neighborhood Hits	1371	Target Neighborhood Hits	419	Shared Neighborhood Hits	226
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TBCD4_HUMAN
θ value	θ > 10 (rank : 2256)	NC score	0.107089 (rank : 1407)
Query Neighborhood Hits	1371	Target Neighborhood Hits	357	Shared Neighborhood Hits	234
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD4_MOUSE
θ value	θ > 10 (rank : 2257)	NC score	0.074850 (rank : 1692)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBK1_HUMAN
θ value	θ > 10 (rank : 2258)	NC score	0.054127 (rank : 2014)
Query Neighborhood Hits	1371	Target Neighborhood Hits	861	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UHD2, Q8IYV3, Q9NUJ5	Gene names	TBK1, NAK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K) (NF-kappa-B-activating kinase).

TBK1_MOUSE
θ value	θ > 10 (rank : 2259)	NC score	0.060689 (rank : 1869)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	177
SwissProt Accessions	Q9WUN2, Q9CT90, Q9DC03	Gene names	Tbk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K).

TCAL5_HUMAN
θ value	θ > 10 (rank : 2260)	NC score	0.054489 (rank : 1999)
Query Neighborhood Hits	1371	Target Neighborhood Hits	806	Shared Neighborhood Hits	147
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCOF_MOUSE
θ value	θ > 10 (rank : 2261)	NC score	0.051777 (rank : 2112)
Query Neighborhood Hits	1371	Target Neighborhood Hits	471	Shared Neighborhood Hits	96
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TEKT2_HUMAN
θ value	θ > 10 (rank : 2262)	NC score	0.140374 (rank : 1159)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

TEKT3_HUMAN
θ value	θ > 10 (rank : 2263)	NC score	0.110526 (rank : 1375)
Query Neighborhood Hits	1371	Target Neighborhood Hits	123	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BXF9, Q8N5R5, Q96M48	Gene names	TEKT3
Domain Architecture
Description	Tektin-3.

TEKT3_MOUSE
θ value	θ > 10 (rank : 2264)	NC score	0.089004 (rank : 1551)
Query Neighborhood Hits	1371	Target Neighborhood Hits	123	Shared Neighborhood Hits	101
SwissProt Accessions	Q6X6Z7	Gene names	Tekt3
Domain Architecture	No domain graphic available
Description	Tektin-3.

TEX14_HUMAN
θ value	θ > 10 (rank : 2265)	NC score	0.089168 (rank : 1549)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1103	Shared Neighborhood Hits	221
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
θ value	θ > 10 (rank : 2266)	NC score	0.133500 (rank : 1207)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1333	Shared Neighborhood Hits	349
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TFAP4_HUMAN
θ value	θ > 10 (rank : 2267)	NC score	0.146921 (rank : 1116)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	164
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

THOC2_HUMAN
θ value	θ > 10 (rank : 2268)	NC score	0.076553 (rank : 1670)
Query Neighborhood Hits	1371	Target Neighborhood Hits	337	Shared Neighborhood Hits	135
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TIM44_HUMAN
θ value	θ > 10 (rank : 2269)	NC score	0.072048 (rank : 1730)
Query Neighborhood Hits	1371	Target Neighborhood Hits	141	Shared Neighborhood Hits	111
SwissProt Accessions	O43615, Q8N193	Gene names	TIMM44, MIMT44, TIM44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

TIM44_MOUSE
θ value	θ > 10 (rank : 2270)	NC score	0.120184 (rank : 1301)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	169
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

TITIN_HUMAN
θ value	θ > 10 (rank : 2271)	NC score	0.056015 (rank : 1966)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2923	Shared Neighborhood Hits	486
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TLK1_HUMAN
θ value	θ > 10 (rank : 2272)	NC score	0.064942 (rank : 1814)
Query Neighborhood Hits	1371	Target Neighborhood Hits	967	Shared Neighborhood Hits	234
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TLK1_MOUSE
θ value	θ > 10 (rank : 2273)	NC score	0.063796 (rank : 1826)
Query Neighborhood Hits	1371	Target Neighborhood Hits	947	Shared Neighborhood Hits	215
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

TMCC1_MOUSE
θ value	θ > 10 (rank : 2274)	NC score	0.129005 (rank : 1240)
Query Neighborhood Hits	1371	Target Neighborhood Hits	315	Shared Neighborhood Hits	236
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TMCC2_HUMAN
θ value	θ > 10 (rank : 2275)	NC score	0.077095 (rank : 1666)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	153
SwissProt Accessions	O75069, Q6ZN09	Gene names	TMCC2, KIAA0481
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 2 (Cerebral protein 11).

TMCC2_MOUSE
θ value	θ > 10 (rank : 2276)	NC score	0.078810 (rank : 1651)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	158
SwissProt Accessions	Q80W04, Q6A061	Gene names	Tmcc2, Kiaa0481
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 2.

TMCC3_HUMAN
θ value	θ > 10 (rank : 2277)	NC score	0.083949 (rank : 1598)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	160
SwissProt Accessions	Q9ULS5, Q8IWB2	Gene names	TMCC3, KIAA1145
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

TMCC3_MOUSE
θ value	θ > 10 (rank : 2278)	NC score	0.079357 (rank : 1645)
Query Neighborhood Hits	1371	Target Neighborhood Hits	192	Shared Neighborhood Hits	143
SwissProt Accessions	Q8R310	Gene names	Tmcc3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

TMCO3_MOUSE
θ value	θ > 10 (rank : 2279)	NC score	0.157772 (rank : 1053)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	194
SwissProt Accessions	Q8BH01, Q3UFX1, Q7TMT5, Q8BGL4, Q8R303	Gene names	Tmco3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domain-containing protein 3 precursor.

TNI3K_HUMAN
θ value	θ > 10 (rank : 2280)	NC score	0.057640 (rank : 1935)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1084	Shared Neighborhood Hits	126
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
θ value	θ > 10 (rank : 2281)	NC score	0.057903 (rank : 1929)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1079	Shared Neighborhood Hits	124
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNK1_HUMAN
θ value	θ > 10 (rank : 2282)	NC score	0.056657 (rank : 1954)
Query Neighborhood Hits	1371	Target Neighborhood Hits	815	Shared Neighborhood Hits	99
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 2283)	NC score	0.057928 (rank : 1927)
Query Neighborhood Hits	1371	Target Neighborhood Hits	806	Shared Neighborhood Hits	99
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TNNT3_HUMAN
θ value	θ > 10 (rank : 2284)	NC score	0.251509 (rank : 692)
Query Neighborhood Hits	1371	Target Neighborhood Hits	327	Shared Neighborhood Hits	264
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

TNNT3_MOUSE
θ value	θ > 10 (rank : 2285)	NC score	0.239628 (rank : 729)
Query Neighborhood Hits	1371	Target Neighborhood Hits	317	Shared Neighborhood Hits	243
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

TOP1_HUMAN
θ value	θ > 10 (rank : 2286)	NC score	0.053962 (rank : 2020)
Query Neighborhood Hits	1371	Target Neighborhood Hits	207	Shared Neighborhood Hits	107
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TOP1_MOUSE
θ value	θ > 10 (rank : 2287)	NC score	0.050495 (rank : 2164)
Query Neighborhood Hits	1371	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TPX2_HUMAN
θ value	θ > 10 (rank : 2288)	NC score	0.075787 (rank : 1680)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

TRAF5_MOUSE
θ value	θ > 10 (rank : 2289)	NC score	0.084100 (rank : 1593)
Query Neighborhood Hits	1371	Target Neighborhood Hits	355	Shared Neighborhood Hits	182
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI15_HUMAN
θ value	θ > 10 (rank : 2290)	NC score	0.056836 (rank : 1949)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	172
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_MOUSE
θ value	θ > 10 (rank : 2291)	NC score	0.088808 (rank : 1552)
Query Neighborhood Hits	1371	Target Neighborhood Hits	620	Shared Neighborhood Hits	323
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI25_HUMAN
θ value	θ > 10 (rank : 2292)	NC score	0.058610 (rank : 1910)
Query Neighborhood Hits	1371	Target Neighborhood Hits	472	Shared Neighborhood Hits	179
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI29_HUMAN
θ value	θ > 10 (rank : 2293)	NC score	0.075783 (rank : 1681)
Query Neighborhood Hits	1371	Target Neighborhood Hits	273	Shared Neighborhood Hits	163
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 2294)	NC score	0.085973 (rank : 1575)
Query Neighborhood Hits	1371	Target Neighborhood Hits	306	Shared Neighborhood Hits	186
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI44_HUMAN
θ value	θ > 10 (rank : 2295)	NC score	0.062976 (rank : 1836)
Query Neighborhood Hits	1371	Target Neighborhood Hits	393	Shared Neighborhood Hits	144
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TS101_HUMAN
θ value	θ > 10 (rank : 2296)	NC score	0.179820 (rank : 926)
Query Neighborhood Hits	1371	Target Neighborhood Hits	359	Shared Neighborhood Hits	243
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

TS101_MOUSE
θ value	θ > 10 (rank : 2297)	NC score	0.159480 (rank : 1041)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	218
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

TSKS_HUMAN
θ value	θ > 10 (rank : 2298)	NC score	0.128422 (rank : 1250)
Query Neighborhood Hits	1371	Target Neighborhood Hits	220	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

TSKS_MOUSE
θ value	θ > 10 (rank : 2299)	NC score	0.116866 (rank : 1323)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	137
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

TTC17_HUMAN
θ value	θ > 10 (rank : 2300)	NC score	0.055749 (rank : 1972)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	53
SwissProt Accessions	Q96AE7	Gene names	TTC17
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 17 (TPR repeat protein 17).

TXD11_HUMAN
θ value	θ > 10 (rank : 2301)	NC score	0.172030 (rank : 973)
Query Neighborhood Hits	1371	Target Neighborhood Hits	402	Shared Neighborhood Hits	245
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

TXLNB_HUMAN
θ value	θ > 10 (rank : 2302)	NC score	0.333375 (rank : 495)
Query Neighborhood Hits	1371	Target Neighborhood Hits	912	Shared Neighborhood Hits	469
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TXLNB_MOUSE
θ value	θ > 10 (rank : 2303)	NC score	0.352834 (rank : 462)
Query Neighborhood Hits	1371	Target Neighborhood Hits	640	Shared Neighborhood Hits	425
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

TXND2_MOUSE
θ value	θ > 10 (rank : 2304)	NC score	0.097048 (rank : 1480)
Query Neighborhood Hits	1371	Target Neighborhood Hits	828	Shared Neighborhood Hits	240
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TYK2_HUMAN
θ value	θ > 10 (rank : 2305)	NC score	0.053000 (rank : 2058)
Query Neighborhood Hits	1371	Target Neighborhood Hits	841	Shared Neighborhood Hits	92
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYK2_MOUSE
θ value	θ > 10 (rank : 2306)	NC score	0.052443 (rank : 2083)
Query Neighborhood Hits	1371	Target Neighborhood Hits	850	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

UBXD8_HUMAN
θ value	θ > 10 (rank : 2307)	NC score	0.057188 (rank : 1942)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	93
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

UBXD8_MOUSE
θ value	θ > 10 (rank : 2308)	NC score	0.060918 (rank : 1865)
Query Neighborhood Hits	1371	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	Q3TDN2, Q3U9W2, Q80TP7, Q80W42	Gene names	Ubxd8, Kiaa0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8.

UFO_HUMAN
θ value	θ > 10 (rank : 2309)	NC score	0.052514 (rank : 2080)
Query Neighborhood Hits	1371	Target Neighborhood Hits	981	Shared Neighborhood Hits	95
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 2310)	NC score	0.052594 (rank : 2074)
Query Neighborhood Hits	1371	Target Neighborhood Hits	988	Shared Neighborhood Hits	94
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

UN84A_HUMAN
θ value	θ > 10 (rank : 2311)	NC score	0.092996 (rank : 1514)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	148
SwissProt Accessions	O94901, Q96CZ7, Q9HA14, Q9UH98	Gene names	UNC84A, KIAA0810, SUN1
Domain Architecture	No domain graphic available
Description	Sad1/unc-84 protein-like 1 (Unc-84 homolog A).

UN84B_HUMAN
θ value	θ > 10 (rank : 2312)	NC score	0.094919 (rank : 1497)
Query Neighborhood Hits	1371	Target Neighborhood Hits	172	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UH99, O75156, Q6B4H1, Q7Z3E3	Gene names	UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2
Domain Architecture	No domain graphic available
Description	Sad1/unc-84-like protein 2 (Rab5-interacting protein) (Rab5IP).

USBP1_HUMAN
θ value	θ > 10 (rank : 2313)	NC score	0.072921 (rank : 1718)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

USBP1_MOUSE
θ value	θ > 10 (rank : 2314)	NC score	0.058424 (rank : 1914)
Query Neighborhood Hits	1371	Target Neighborhood Hits	115	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R370	Gene names	Ushbp1
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1).

USH1C_HUMAN
θ value	θ > 10 (rank : 2315)	NC score	0.071672 (rank : 1735)
Query Neighborhood Hits	1371	Target Neighborhood Hits	327	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

UT14A_HUMAN
θ value	θ > 10 (rank : 2316)	NC score	0.089325 (rank : 1547)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

UT14A_MOUSE
θ value	θ > 10 (rank : 2317)	NC score	0.086861 (rank : 1568)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	115
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

UT14B_MOUSE
θ value	θ > 10 (rank : 2318)	NC score	0.073227 (rank : 1713)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	135
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

UT14C_HUMAN
θ value	θ > 10 (rank : 2319)	NC score	0.098478 (rank : 1472)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	137
SwissProt Accessions	Q5TAP6, Q5FWG3, Q92555	Gene names	UTP14C, KIAA0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog C.

UVRAG_HUMAN
θ value	θ > 10 (rank : 2320)	NC score	0.106449 (rank : 1414)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	120
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

VCXC_HUMAN
θ value	θ > 10 (rank : 2321)	NC score	0.053081 (rank : 2055)
Query Neighborhood Hits	1371	Target Neighborhood Hits	139	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

VDP_MOUSE
θ value	θ > 10 (rank : 2322)	NC score	0.313698 (rank : 535)
Query Neighborhood Hits	1371	Target Neighborhood Hits	469	Shared Neighborhood Hits	340
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VGF_HUMAN
θ value	θ > 10 (rank : 2323)	NC score	0.058317 (rank : 1915)
Query Neighborhood Hits	1371	Target Neighborhood Hits	167	Shared Neighborhood Hits	54
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

VINC_HUMAN
θ value	θ > 10 (rank : 2324)	NC score	0.070098 (rank : 1751)
Query Neighborhood Hits	1371	Target Neighborhood Hits	145	Shared Neighborhood Hits	85
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_MOUSE
θ value	θ > 10 (rank : 2325)	NC score	0.060110 (rank : 1885)
Query Neighborhood Hits	1371	Target Neighborhood Hits	135	Shared Neighborhood Hits	79
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

WDR60_HUMAN
θ value	θ > 10 (rank : 2326)	NC score	0.118025 (rank : 1315)
Query Neighborhood Hits	1371	Target Neighborhood Hits	286	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

WDR60_MOUSE
θ value	θ > 10 (rank : 2327)	NC score	0.169265 (rank : 987)
Query Neighborhood Hits	1371	Target Neighborhood Hits	344	Shared Neighborhood Hits	183
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

WNK2_HUMAN
θ value	θ > 10 (rank : 2328)	NC score	0.050887 (rank : 2150)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1407	Shared Neighborhood Hits	165
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK3_HUMAN
θ value	θ > 10 (rank : 2329)	NC score	0.051236 (rank : 2136)
Query Neighborhood Hits	1371	Target Neighborhood Hits	948	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

WTAP_HUMAN
θ value	θ > 10 (rank : 2330)	NC score	0.220684 (rank : 786)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	203
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

WTAP_MOUSE
θ value	θ > 10 (rank : 2331)	NC score	0.215436 (rank : 804)
Query Neighborhood Hits	1371	Target Neighborhood Hits	250	Shared Neighborhood Hits	199
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

WWC1_HUMAN
θ value	θ > 10 (rank : 2332)	NC score	0.148932 (rank : 1100)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	203
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 2333)	NC score	0.148374 (rank : 1104)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	199
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWC3_HUMAN
θ value	θ > 10 (rank : 2334)	NC score	0.107616 (rank : 1400)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	124
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

XBP1_HUMAN
θ value	θ > 10 (rank : 2335)	NC score	0.060629 (rank : 1871)
Query Neighborhood Hits	1371	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

XL3A_MOUSE
θ value	θ > 10 (rank : 2336)	NC score	0.109739 (rank : 1381)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	108
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

XL3B_MOUSE
θ value	θ > 10 (rank : 2337)	NC score	0.115538 (rank : 1338)
Query Neighborhood Hits	1371	Target Neighborhood Hits	146	Shared Neighborhood Hits	120
SwissProt Accessions	Q61806, Q61244	Gene names	Xlr3b
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A (XLR-related protein A12).

XRCC4_HUMAN
θ value	θ > 10 (rank : 2338)	NC score	0.064438 (rank : 1817)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

YO11_MOUSE
θ value	θ > 10 (rank : 2339)	NC score	0.223361 (rank : 774)
Query Neighborhood Hits	1371	Target Neighborhood Hits	272	Shared Neighborhood Hits	215
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

YSK4_HUMAN
θ value	θ > 10 (rank : 2340)	NC score	0.050710 (rank : 2160)
Query Neighborhood Hits	1371	Target Neighborhood Hits	921	Shared Neighborhood Hits	120
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

YTDC1_HUMAN
θ value	θ > 10 (rank : 2341)	NC score	0.061882 (rank : 1854)
Query Neighborhood Hits	1371	Target Neighborhood Hits	458	Shared Neighborhood Hits	143
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZAP70_HUMAN
θ value	θ > 10 (rank : 2342)	NC score	0.073944 (rank : 1703)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	126
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 2343)	NC score	0.074434 (rank : 1699)
Query Neighborhood Hits	1371	Target Neighborhood Hits	905	Shared Neighborhood Hits	128
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZC11A_MOUSE
θ value	θ > 10 (rank : 2344)	NC score	0.057919 (rank : 1928)
Query Neighborhood Hits	1371	Target Neighborhood Hits	216	Shared Neighborhood Hits	100
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZFY16_HUMAN
θ value	θ > 10 (rank : 2345)	NC score	0.067498 (rank : 1788)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
θ value	θ > 10 (rank : 2346)	NC score	0.068650 (rank : 1768)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	28
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFY19_HUMAN
θ value	θ > 10 (rank : 2347)	NC score	0.065421 (rank : 1808)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	53
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
θ value	θ > 10 (rank : 2348)	NC score	0.066300 (rank : 1801)
Query Neighborhood Hits	1371	Target Neighborhood Hits	143	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY21_HUMAN
θ value	θ > 10 (rank : 2349)	NC score	0.067507 (rank : 1787)
Query Neighborhood Hits	1371	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
θ value	θ > 10 (rank : 2350)	NC score	0.068059 (rank : 1777)
Query Neighborhood Hits	1371	Target Neighborhood Hits	72	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
θ value	θ > 10 (rank : 2351)	NC score	0.077509 (rank : 1661)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFYV1_HUMAN
θ value	θ > 10 (rank : 2352)	NC score	0.053172 (rank : 2049)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
θ value	θ > 10 (rank : 2353)	NC score	0.050736 (rank : 2158)
Query Neighborhood Hits	1371	Target Neighborhood Hits	153	Shared Neighborhood Hits	30
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ZFYV9_HUMAN
θ value	θ > 10 (rank : 2354)	NC score	0.072931 (rank : 1717)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZMAT2_HUMAN
θ value	θ > 10 (rank : 2355)	NC score	0.051900 (rank : 2107)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	Q96NC0	Gene names	ZMAT2
Domain Architecture	No domain graphic available
Description	Zinc finger matrin type 2.

ZMAT2_MOUSE
θ value	θ > 10 (rank : 2356)	NC score	0.051900 (rank : 2108)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CPW7, Q5EBK0	Gene names	Zmat2
Domain Architecture	No domain graphic available
Description	Zinc finger matrin type 2.

ZRF1_HUMAN
θ value	θ > 10 (rank : 2357)	NC score	0.226245 (rank : 766)
Query Neighborhood Hits	1371	Target Neighborhood Hits	457	Shared Neighborhood Hits	291
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

Hits sorted by NC score

ITSN2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1371	Shared Neighborhood Hits	1371
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITSN2_HUMAN
NC score	0.962207 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1173	Shared Neighborhood Hits	1032
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN1_HUMAN
NC score	0.933991 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1757	Shared Neighborhood Hits	1093
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.928591 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1669	Shared Neighborhood Hits	1073
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ARHG7_MOUSE
NC score	0.593367 (rank : 5)	θ value	2.43343e-21 (rank : 18)
Query Neighborhood Hits	1371	Target Neighborhood Hits	396	Shared Neighborhood Hits	342
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG7_HUMAN
NC score	0.579482 (rank : 6)	θ value	1.09232e-21 (rank : 14)
Query Neighborhood Hits	1371	Target Neighborhood Hits	347	Shared Neighborhood Hits	284
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

DNMBP_HUMAN
NC score	0.577536 (rank : 7)	θ value	5.43371e-13 (rank : 68)
Query Neighborhood Hits	1371	Target Neighborhood Hits	413	Shared Neighborhood Hits	312
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
NC score	0.575997 (rank : 8)	θ value	5.25075e-16 (rank : 40)
Query Neighborhood Hits	1371	Target Neighborhood Hits	435	Shared Neighborhood Hits	297
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ARHG4_HUMAN
NC score	0.564485 (rank : 9)	θ value	4.58923e-20 (rank : 23)
Query Neighborhood Hits	1371	Target Neighborhood Hits	242	Shared Neighborhood Hits	223
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG6_MOUSE
NC score	0.563980 (rank : 10)	θ value	3.88503e-19 (rank : 29)
Query Neighborhood Hits	1371	Target Neighborhood Hits	394	Shared Neighborhood Hits	340
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG6_HUMAN
NC score	0.560207 (rank : 11)	θ value	1.74391e-19 (rank : 27)
Query Neighborhood Hits	1371	Target Neighborhood Hits	376	Shared Neighborhood Hits	317
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG9_HUMAN
NC score	0.555760 (rank : 12)	θ value	5.99374e-20 (rank : 25)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	216
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
NC score	0.555107 (rank : 13)	θ value	7.82807e-20 (rank : 26)
Query Neighborhood Hits	1371	Target Neighborhood Hits	234	Shared Neighborhood Hits	218
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

EP15R_HUMAN
NC score	0.547224 (rank : 14)	θ value	4.74913e-17 (rank : 35)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1083	Shared Neighborhood Hits	626
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
NC score	0.546257 (rank : 15)	θ value	2.97466e-19 (rank : 28)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1135	Shared Neighborhood Hits	634
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
NC score	0.543408 (rank : 16)	θ value	1.42661e-21 (rank : 15)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1021	Shared Neighborhood Hits	611
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
NC score	0.538355 (rank : 17)	θ value	2.20094e-22 (rank : 12)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	524
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ARHG4_MOUSE
NC score	0.532794 (rank : 18)	θ value	3.51386e-20 (rank : 22)
Query Neighborhood Hits	1371	Target Neighborhood Hits	185	Shared Neighborhood Hits	173
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CCD46_HUMAN
NC score	0.525756 (rank : 19)	θ value	1.2105e-12 (rank : 74)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1430	Shared Neighborhood Hits	763
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
NC score	0.525245 (rank : 20)	θ value	4.91457e-14 (rank : 54)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1405	Shared Neighborhood Hits	764
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CP250_HUMAN
NC score	0.523438 (rank : 21)	θ value	5.43371e-13 (rank : 67)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1805	Shared Neighborhood Hits	825
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

EEA1_HUMAN
NC score	0.521225 (rank : 22)	θ value	1.06045e-08 (rank : 135)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1796	Shared Neighborhood Hits	814
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RGNEF_MOUSE
NC score	0.520580 (rank : 23)	θ value	2.13179e-17 (rank : 34)
Query Neighborhood Hits	1371	Target Neighborhood Hits	641	Shared Neighborhood Hits	416
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

PIBF1_HUMAN
NC score	0.520481 (rank : 24)	θ value	1.38499e-08 (rank : 141)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1041	Shared Neighborhood Hits	654
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

CENPF_HUMAN
NC score	0.518931 (rank : 25)	θ value	3.29651e-10 (rank : 114)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1932	Shared Neighborhood Hits	832
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GOGA4_HUMAN
NC score	0.518495 (rank : 26)	θ value	4.0297e-08 (rank : 161)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2034	Shared Neighborhood Hits	863
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RIMB1_MOUSE
NC score	0.517707 (rank : 27)	θ value	0.000121331 (rank : 403)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1376	Shared Neighborhood Hits	772
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

VAV_MOUSE
NC score	0.517079 (rank : 28)	θ value	3.52202e-12 (rank : 83)
Query Neighborhood Hits	1371	Target Neighborhood Hits	430	Shared Neighborhood Hits	291
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

CP135_MOUSE
NC score	0.516596 (rank : 29)	θ value	2.43908e-13 (rank : 62)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1278	Shared Neighborhood Hits	718
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CCD41_MOUSE
NC score	0.516339 (rank : 30)	θ value	1.02475e-11 (rank : 88)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1399	Shared Neighborhood Hits	738
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CEP63_HUMAN
NC score	0.515697 (rank : 31)	θ value	2.21117e-06 (rank : 245)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1005	Shared Neighborhood Hits	633
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

SH3K1_HUMAN
NC score	0.515351 (rank : 32)	θ value	3.88503e-19 (rank : 30)
Query Neighborhood Hits	1371	Target Neighborhood Hits	341	Shared Neighborhood Hits	263
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

CP250_MOUSE
NC score	0.515038 (rank : 33)	θ value	2.36244e-08 (rank : 149)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1583	Shared Neighborhood Hits	771
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

RB6I2_MOUSE
NC score	0.514739 (rank : 34)	θ value	1.02475e-11 (rank : 89)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1433	Shared Neighborhood Hits	762
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RB6I2_HUMAN
NC score	0.514323 (rank : 35)	θ value	1.17247e-07 (rank : 179)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1584	Shared Neighborhood Hits	788
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CCD41_HUMAN
NC score	0.514281 (rank : 36)	θ value	3.64472e-09 (rank : 131)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1139	Shared Neighborhood Hits	655
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CI093_HUMAN
NC score	0.514039 (rank : 37)	θ value	3.08544e-08 (rank : 156)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1088	Shared Neighborhood Hits	665
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

TRIPB_HUMAN
NC score	0.514036 (rank : 38)	θ value	4.1701e-05 (rank : 368)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1587	Shared Neighborhood Hits	779
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

GRAP1_MOUSE
NC score	0.512623 (rank : 39)	θ value	4.0297e-08 (rank : 163)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1234	Shared Neighborhood Hits	723
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

AKAP9_HUMAN
NC score	0.512443 (rank : 40)	θ value	2.88788e-06 (rank : 254)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1710	Shared Neighborhood Hits	802
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

VAV_HUMAN
NC score	0.512275 (rank : 41)	θ value	1.74796e-11 (rank : 95)
Query Neighborhood Hits	1371	Target Neighborhood Hits	452	Shared Neighborhood Hits	292
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

HMMR_MOUSE
NC score	0.512212 (rank : 42)	θ value	3.41135e-07 (rank : 193)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1178	Shared Neighborhood Hits	679
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CE290_HUMAN
NC score	0.512143 (rank : 43)	θ value	6.87365e-08 (rank : 170)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1553	Shared Neighborhood Hits	776
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

RAD50_MOUSE
NC score	0.512016 (rank : 44)	θ value	2.52405e-10 (rank : 111)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1366	Shared Neighborhood Hits	716
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SYCP1_MOUSE
NC score	0.511977 (rank : 45)	θ value	2.88788e-06 (rank : 263)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1456	Shared Neighborhood Hits	755
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

NUMA1_HUMAN
NC score	0.511840 (rank : 46)	θ value	2.44474e-05 (rank : 345)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1523	Shared Neighborhood Hits	761
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

HMMR_HUMAN
NC score	0.511600 (rank : 47)	θ value	9.92553e-07 (rank : 222)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1082	Shared Neighborhood Hits	653
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CP135_HUMAN
NC score	0.511165 (rank : 48)	θ value	2.98157e-11 (rank : 96)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1290	Shared Neighborhood Hits	703
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CF060_HUMAN
NC score	0.511053 (rank : 49)	θ value	8.40245e-06 (rank : 288)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1270	Shared Neighborhood Hits	715
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

EEA1_MOUSE
NC score	0.510817 (rank : 50)	θ value	0.00035302 (rank : 443)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1637	Shared Neighborhood Hits	782
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GOGA3_MOUSE
NC score	0.510723 (rank : 51)	θ value	8.97725e-08 (rank : 175)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1437	Shared Neighborhood Hits	756
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGB1_HUMAN
NC score	0.510618 (rank : 52)	θ value	1.06045e-08 (rank : 137)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2297	Shared Neighborhood Hits	876
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GOGA4_MOUSE
NC score	0.510226 (rank : 53)	θ value	1.38499e-08 (rank : 139)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1939	Shared Neighborhood Hits	852
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

NGEF_HUMAN
NC score	0.510113 (rank : 54)	θ value	1.5773e-20 (rank : 20)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	143
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ERC2_MOUSE
NC score	0.509716 (rank : 55)	θ value	1.133e-10 (rank : 107)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1166	Shared Neighborhood Hits	697
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

CN145_HUMAN
NC score	0.509528 (rank : 56)	θ value	1.43324e-05 (rank : 310)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1196	Shared Neighborhood Hits	705
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

REST_HUMAN
NC score	0.509504 (rank : 57)	θ value	1.133e-10 (rank : 109)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1605	Shared Neighborhood Hits	794
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MD1L1_MOUSE
NC score	0.509029 (rank : 58)	θ value	2.88788e-06 (rank : 257)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1001	Shared Neighborhood Hits	627
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

FLIP1_HUMAN
NC score	0.508801 (rank : 59)	θ value	4.45536e-07 (rank : 197)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1405	Shared Neighborhood Hits	757
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

SYCP1_HUMAN
NC score	0.508456 (rank : 60)	θ value	1.99992e-07 (rank : 185)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1313	Shared Neighborhood Hits	728
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

VAV2_HUMAN
NC score	0.507981 (rank : 61)	θ value	2.69671e-12 (rank : 78)
Query Neighborhood Hits	1371	Target Neighborhood Hits	453	Shared Neighborhood Hits	287
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

TRHY_HUMAN
NC score	0.507718 (rank : 62)	θ value	1.09739e-05 (rank : 307)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1385	Shared Neighborhood Hits	722
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CI039_HUMAN
NC score	0.507384 (rank : 63)	θ value	5.62301e-10 (rank : 115)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1171	Shared Neighborhood Hits	668
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

ARHG5_HUMAN
NC score	0.506674 (rank : 64)	θ value	6.41864e-14 (rank : 57)
Query Neighborhood Hits	1371	Target Neighborhood Hits	172	Shared Neighborhood Hits	143
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHGG_MOUSE
NC score	0.506643 (rank : 65)	θ value	3.62785e-25 (rank : 8)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	114
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

NGEF_MOUSE
NC score	0.506476 (rank : 66)	θ value	1.86321e-21 (rank : 16)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	158
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

GOGA1_MOUSE
NC score	0.505536 (rank : 67)	θ value	2.21117e-06 (rank : 246)
Query Neighborhood Hits	1371	Target Neighborhood Hits	994	Shared Neighborhood Hits	624
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

ERC2_HUMAN
NC score	0.505445 (rank : 68)	θ value	1.133e-10 (rank : 106)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1156	Shared Neighborhood Hits	686
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CD2AP_MOUSE
NC score	0.505246 (rank : 69)	θ value	2.13179e-17 (rank : 32)
Query Neighborhood Hits	1371	Target Neighborhood Hits	336	Shared Neighborhood Hits	249
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CING_MOUSE
NC score	0.505063 (rank : 70)	θ value	1.29631e-06 (rank : 230)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1432	Shared Neighborhood Hits	750
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

VAV2_MOUSE
NC score	0.504947 (rank : 71)	θ value	2.69671e-12 (rank : 79)
Query Neighborhood Hits	1371	Target Neighborhood Hits	456	Shared Neighborhood Hits	283
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

GOGA1_HUMAN
NC score	0.504897 (rank : 72)	θ value	6.43352e-06 (rank : 285)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1222	Shared Neighborhood Hits	693
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

RAD50_HUMAN
NC score	0.504893 (rank : 73)	θ value	6.87365e-08 (rank : 173)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1317	Shared Neighborhood Hits	692
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

IFT81_MOUSE
NC score	0.504704 (rank : 74)	θ value	5.08577e-11 (rank : 99)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	619
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

GOGA5_MOUSE
NC score	0.503334 (rank : 75)	θ value	8.67504e-11 (rank : 103)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1434	Shared Neighborhood Hits	739
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CD2AP_HUMAN
NC score	0.503158 (rank : 76)	θ value	8.95645e-16 (rank : 41)
Query Neighborhood Hits	1371	Target Neighborhood Hits	315	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

GAS8_HUMAN
NC score	0.502449 (rank : 77)	θ value	8.97725e-08 (rank : 174)
Query Neighborhood Hits	1371	Target Neighborhood Hits	819	Shared Neighborhood Hits	585
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GOGA6_HUMAN
NC score	0.501885 (rank : 78)	θ value	1.09739e-05 (rank : 300)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1007	Shared Neighborhood Hits	655
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

AZI1_HUMAN
NC score	0.501864 (rank : 79)	θ value	7.59969e-07 (rank : 215)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1000	Shared Neighborhood Hits	626
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

KTN1_MOUSE
NC score	0.501844 (rank : 80)	θ value	8.40245e-06 (rank : 290)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1324	Shared Neighborhood Hits	725
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

SH3K1_MOUSE
NC score	0.501809 (rank : 81)	θ value	6.20254e-17 (rank : 36)
Query Neighborhood Hits	1371	Target Neighborhood Hits	332	Shared Neighborhood Hits	261
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

TPR_HUMAN
NC score	0.501067 (rank : 82)	θ value	1.25267e-09 (rank : 117)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1921	Shared Neighborhood Hits	822
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

NIN_HUMAN
NC score	0.501016 (rank : 83)	θ value	4.45536e-07 (rank : 202)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1416	Shared Neighborhood Hits	741
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

GOGA3_HUMAN
NC score	0.500584 (rank : 84)	θ value	1.43324e-05 (rank : 313)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1317	Shared Neighborhood Hits	718
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA5_HUMAN
NC score	0.500472 (rank : 85)	θ value	4.0297e-08 (rank : 162)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1168	Shared Neighborhood Hits	679
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

TAXB1_HUMAN
NC score	0.499518 (rank : 86)	θ value	2.79066e-09 (rank : 130)
Query Neighborhood Hits	1371	Target Neighborhood Hits	829	Shared Neighborhood Hits	559
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

GCC2_MOUSE
NC score	0.498796 (rank : 87)	θ value	2.13673e-09 (rank : 121)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1619	Shared Neighborhood Hits	786
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CJ118_MOUSE
NC score	0.498365 (rank : 88)	θ value	3.19293e-05 (rank : 348)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1132	Shared Neighborhood Hits	675
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

PCNT_HUMAN
NC score	0.497718 (rank : 89)	θ value	1.29631e-06 (rank : 234)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1551	Shared Neighborhood Hits	763
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CE152_HUMAN
NC score	0.497684 (rank : 90)	θ value	8.40245e-06 (rank : 287)
Query Neighborhood Hits	1371	Target Neighborhood Hits	976	Shared Neighborhood Hits	609
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

DESP_HUMAN
NC score	0.497408 (rank : 91)	θ value	1.80886e-08 (rank : 146)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1470	Shared Neighborhood Hits	774
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

NIN_MOUSE
NC score	0.497405 (rank : 92)	θ value	3.41135e-07 (rank : 196)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1376	Shared Neighborhood Hits	727
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CCD39_MOUSE
NC score	0.497300 (rank : 93)	θ value	1.87187e-05 (rank : 327)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1026	Shared Neighborhood Hits	640
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

ARHGG_HUMAN
NC score	0.497251 (rank : 94)	θ value	2.20094e-22 (rank : 11)
Query Neighborhood Hits	1371	Target Neighborhood Hits	129	Shared Neighborhood Hits	110
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

FLIP1_MOUSE
NC score	0.496508 (rank : 95)	θ value	0.00035302 (rank : 444)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1176	Shared Neighborhood Hits	682
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

RBP24_HUMAN
NC score	0.495879 (rank : 96)	θ value	4.45536e-07 (rank : 203)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1559	Shared Neighborhood Hits	749
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.495621 (rank : 97)	θ value	4.45536e-07 (rank : 198)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1558	Shared Neighborhood Hits	748
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

IFT74_HUMAN
NC score	0.494989 (rank : 98)	θ value	0.00020696 (rank : 419)
Query Neighborhood Hits	1371	Target Neighborhood Hits	949	Shared Neighborhood Hits	591
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SDCG8_HUMAN
NC score	0.494727 (rank : 99)	θ value	7.1131e-05 (rank : 386)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1002	Shared Neighborhood Hits	636
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

REST_MOUSE
NC score	0.494245 (rank : 100)	θ value	4.92598e-06 (rank : 275)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1506	Shared Neighborhood Hits	740
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CING_HUMAN
NC score	0.493766 (rank : 101)	θ value	0.00298849 (rank : 549)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1275	Shared Neighborhood Hits	720
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CK5P2_HUMAN
NC score	0.493623 (rank : 102)	θ value	1.63604e-09 (rank : 120)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1433	Shared Neighborhood Hits	754
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MD1L1_HUMAN
NC score	0.493568 (rank : 103)	θ value	9.29e-05 (rank : 390)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	584
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CCD39_HUMAN
NC score	0.492384 (rank : 104)	θ value	1.87187e-05 (rank : 326)
Query Neighborhood Hits	1371	Target Neighborhood Hits	868	Shared Neighborhood Hits	581
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CROCC_HUMAN
NC score	0.491047 (rank : 105)	θ value	0.000461057 (rank : 453)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1409	Shared Neighborhood Hits	734
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GRAP1_HUMAN
NC score	0.490172 (rank : 106)	θ value	0.00228821 (rank : 532)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	618
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

CROCC_MOUSE
NC score	0.489987 (rank : 107)	θ value	0.000786445 (rank : 480)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1460	Shared Neighborhood Hits	752
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

KTN1_HUMAN
NC score	0.489892 (rank : 108)	θ value	0.000158464 (rank : 412)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1197	Shared Neighborhood Hits	661
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KMHN1_MOUSE
NC score	0.489870 (rank : 109)	θ value	4.1701e-05 (rank : 358)
Query Neighborhood Hits	1371	Target Neighborhood Hits	949	Shared Neighborhood Hits	597
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

TAXB1_MOUSE
NC score	0.489531 (rank : 110)	θ value	4.45536e-07 (rank : 206)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	577
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

K0555_HUMAN
NC score	0.489238 (rank : 111)	θ value	1.43324e-05 (rank : 316)
Query Neighborhood Hits	1371	Target Neighborhood Hits	880	Shared Neighborhood Hits	572
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

AZI1_MOUSE
NC score	0.488601 (rank : 112)	θ value	0.00298849 (rank : 544)
Query Neighborhood Hits	1371	Target Neighborhood Hits	990	Shared Neighborhood Hits	645
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

IFT81_HUMAN
NC score	0.488446 (rank : 113)	θ value	0.000461057 (rank : 455)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	599
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

HOOK3_HUMAN
NC score	0.488352 (rank : 114)	θ value	2.61198e-07 (rank : 190)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1070	Shared Neighborhood Hits	650
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CCD21_MOUSE
NC score	0.488291 (rank : 115)	θ value	1.43324e-05 (rank : 309)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1135	Shared Neighborhood Hits	651
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

ARHG3_HUMAN
NC score	0.488168 (rank : 116)	θ value	1.09232e-21 (rank : 13)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

OPTN_MOUSE
NC score	0.487981 (rank : 117)	θ value	9.92553e-07 (rank : 227)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1120	Shared Neighborhood Hits	652
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RBCC1_MOUSE
NC score	0.487078 (rank : 118)	θ value	1.29631e-06 (rank : 235)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1048	Shared Neighborhood Hits	644
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

GOGA2_MOUSE
NC score	0.486716 (rank : 119)	θ value	0.00869519 (rank : 606)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	601
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

ARHG3_MOUSE
NC score	0.486435 (rank : 120)	θ value	2.43343e-21 (rank : 17)
Query Neighborhood Hits	1371	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

HOOK3_MOUSE
NC score	0.486234 (rank : 121)	θ value	1.99992e-07 (rank : 182)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1007	Shared Neighborhood Hits	631
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

SMC1A_MOUSE
NC score	0.485854 (rank : 122)	θ value	4.92598e-06 (rank : 277)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1384	Shared Neighborhood Hits	767
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

IFT74_MOUSE
NC score	0.485171 (rank : 123)	θ value	0.0193708 (rank : 663)
Query Neighborhood Hits	1371	Target Neighborhood Hits	939	Shared Neighborhood Hits	594
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

ARHG8_HUMAN
NC score	0.484618 (rank : 124)	θ value	5.42112e-21 (rank : 19)
Query Neighborhood Hits	1371	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

KMHN1_HUMAN
NC score	0.484256 (rank : 125)	θ value	3.77169e-06 (rank : 267)
Query Neighborhood Hits	1371	Target Neighborhood Hits	950	Shared Neighborhood Hits	589
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

CYLN2_HUMAN
NC score	0.484153 (rank : 126)	θ value	4.0297e-08 (rank : 160)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1004	Shared Neighborhood Hits	627
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CCD21_HUMAN
NC score	0.483952 (rank : 127)	θ value	2.88788e-06 (rank : 256)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1228	Shared Neighborhood Hits	670
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

SMC2_HUMAN
NC score	0.483776 (rank : 128)	θ value	1.69304e-06 (rank : 242)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1405	Shared Neighborhood Hits	756
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

PCNT_MOUSE
NC score	0.483637 (rank : 129)	θ value	0.00298849 (rank : 556)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1207	Shared Neighborhood Hits	688
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RABE1_HUMAN
NC score	0.482879 (rank : 130)	θ value	5.44631e-05 (rank : 376)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1104	Shared Neighborhood Hits	665
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CCD19_HUMAN
NC score	0.482780 (rank : 131)	θ value	0.00175202 (rank : 512)
Query Neighborhood Hits	1371	Target Neighborhood Hits	639	Shared Neighborhood Hits	516
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

SMC3_MOUSE
NC score	0.482522 (rank : 132)	θ value	4.92598e-06 (rank : 279)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1187	Shared Neighborhood Hits	705
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SAS6_MOUSE
NC score	0.482473 (rank : 133)	θ value	4.1701e-05 (rank : 366)
Query Neighborhood Hits	1371	Target Neighborhood Hits	931	Shared Neighborhood Hits	592
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

PEPL_HUMAN
NC score	0.482339 (rank : 134)	θ value	2.88788e-06 (rank : 260)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1141	Shared Neighborhood Hits	682
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SMC3_HUMAN
NC score	0.482127 (rank : 135)	θ value	4.92598e-06 (rank : 278)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1186	Shared Neighborhood Hits	704
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

INCE_HUMAN
NC score	0.482024 (rank : 136)	θ value	0.000461057 (rank : 456)
Query Neighborhood Hits	1371	Target Neighborhood Hits	978	Shared Neighborhood Hits	586
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

CASP_MOUSE
NC score	0.481878 (rank : 137)	θ value	7.59969e-07 (rank : 216)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1152	Shared Neighborhood Hits	675
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

TMF1_HUMAN
NC score	0.481824 (rank : 138)	θ value	0.00390308 (rank : 573)
Query Neighborhood Hits	1371	Target Neighborhood Hits	987	Shared Neighborhood Hits	600
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

INCE_MOUSE
NC score	0.481454 (rank : 139)	θ value	0.000786445 (rank : 482)
Query Neighborhood Hits	1371	Target Neighborhood Hits	903	Shared Neighborhood Hits	598
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

BPAEA_MOUSE
NC score	0.481007 (rank : 140)	θ value	5.26297e-08 (rank : 165)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1480	Shared Neighborhood Hits	757
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RIMB1_HUMAN
NC score	0.480201 (rank : 141)	θ value	0.000602161 (rank : 471)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1479	Shared Neighborhood Hits	735
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ARHG8_MOUSE
NC score	0.480199 (rank : 142)	θ value	4.58923e-20 (rank : 24)
Query Neighborhood Hits	1371	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

CN145_MOUSE
NC score	0.480187 (rank : 143)	θ value	0.0736092 (rank : 751)
Query Neighborhood Hits	1371	Target Neighborhood Hits	916	Shared Neighborhood Hits	596
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

SMC1A_HUMAN
NC score	0.479724 (rank : 144)	θ value	3.19293e-05 (rank : 354)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1346	Shared Neighborhood Hits	750
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

PEPL_MOUSE
NC score	0.479414 (rank : 145)	θ value	0.000270298 (rank : 432)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1105	Shared Neighborhood Hits	679
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CYLN2_MOUSE
NC score	0.479395 (rank : 146)	θ value	2.36244e-08 (rank : 150)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1002	Shared Neighborhood Hits	628
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CK5P2_MOUSE
NC score	0.479358 (rank : 147)	θ value	0.000786445 (rank : 478)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1151	Shared Neighborhood Hits	663
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CASP_HUMAN
NC score	0.479194 (rank : 148)	θ value	3.41135e-07 (rank : 192)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1131	Shared Neighborhood Hits	670
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SM1L2_HUMAN
NC score	0.478641 (rank : 149)	θ value	2.36244e-08 (rank : 154)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1019	Shared Neighborhood Hits	649
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

RABE1_MOUSE
NC score	0.478107 (rank : 150)	θ value	0.000270298 (rank : 433)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1105	Shared Neighborhood Hits	675
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

HOOK1_HUMAN
NC score	0.476824 (rank : 151)	θ value	0.000121331 (rank : 395)
Query Neighborhood Hits	1371	Target Neighborhood Hits	942	Shared Neighborhood Hits	604
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

CCHCR_MOUSE
NC score	0.476052 (rank : 152)	θ value	0.00665767 (rank : 592)
Query Neighborhood Hits	1371	Target Neighborhood Hits	932	Shared Neighborhood Hits	604
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

RBCC1_HUMAN
NC score	0.475968 (rank : 153)	θ value	0.000121331 (rank : 401)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1023	Shared Neighborhood Hits	611
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CJ118_HUMAN
NC score	0.475861 (rank : 154)	θ value	0.00035302 (rank : 441)
Query Neighborhood Hits	1371	Target Neighborhood Hits	937	Shared Neighborhood Hits	597
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

MY18A_HUMAN
NC score	0.475696 (rank : 155)	θ value	7.09661e-13 (rank : 71)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1929	Shared Neighborhood Hits	841
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

VAV3_HUMAN
NC score	0.475355 (rank : 156)	θ value	2.13673e-09 (rank : 122)
Query Neighborhood Hits	1371	Target Neighborhood Hits	398	Shared Neighborhood Hits	258
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

FYCO1_MOUSE
NC score	0.474762 (rank : 157)	θ value	0.279714 (rank : 878)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1059	Shared Neighborhood Hits	627
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

CCDC6_HUMAN
NC score	0.474722 (rank : 158)	θ value	0.00228821 (rank : 530)
Query Neighborhood Hits	1371	Target Neighborhood Hits	723	Shared Neighborhood Hits	511
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

SWP70_HUMAN
NC score	0.473962 (rank : 159)	θ value	0.000158464 (rank : 415)
Query Neighborhood Hits	1371	Target Neighborhood Hits	973	Shared Neighborhood Hits	625
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CALD1_HUMAN
NC score	0.473730 (rank : 160)	θ value	0.00869519 (rank : 603)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	583
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

VAV3_MOUSE
NC score	0.473186 (rank : 161)	θ value	2.13673e-09 (rank : 123)
Query Neighborhood Hits	1371	Target Neighborhood Hits	404	Shared Neighborhood Hits	265
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

SWP70_MOUSE
NC score	0.472885 (rank : 162)	θ value	0.00020696 (rank : 422)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1097	Shared Neighborhood Hits	664
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

RUFY2_HUMAN
NC score	0.472734 (rank : 163)	θ value	8.40245e-06 (rank : 295)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1208	Shared Neighborhood Hits	676
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CENPE_HUMAN
NC score	0.472535 (rank : 164)	θ value	1.33837e-11 (rank : 91)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2060	Shared Neighborhood Hits	861
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

LRC45_MOUSE
NC score	0.470682 (rank : 165)	θ value	0.000121331 (rank : 397)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	609
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

HOOK1_MOUSE
NC score	0.470463 (rank : 166)	θ value	0.000158464 (rank : 410)
Query Neighborhood Hits	1371	Target Neighborhood Hits	910	Shared Neighborhood Hits	581
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

MY18A_MOUSE
NC score	0.470172 (rank : 167)	θ value	1.74796e-11 (rank : 93)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1989	Shared Neighborhood Hits	843
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SDCG8_MOUSE
NC score	0.469544 (rank : 168)	θ value	0.0961366 (rank : 790)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	598
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CCD13_HUMAN
NC score	0.469526 (rank : 169)	θ value	0.00020696 (rank : 418)
Query Neighborhood Hits	1371	Target Neighborhood Hits	721	Shared Neighborhood Hits	492
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

IF3A_MOUSE
NC score	0.467419 (rank : 170)	θ value	5.44631e-05 (rank : 373)
Query Neighborhood Hits	1371	Target Neighborhood Hits	871	Shared Neighborhood Hits	597
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

VINEX_HUMAN
NC score	0.466967 (rank : 171)	θ value	9.90251e-15 (rank : 50)
Query Neighborhood Hits	1371	Target Neighborhood Hits	270	Shared Neighborhood Hits	215
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

NEMO_HUMAN
NC score	0.465970 (rank : 172)	θ value	0.00020696 (rank : 421)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	569
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

FYCO1_HUMAN
NC score	0.465512 (rank : 173)	θ value	0.0961366 (rank : 782)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1149	Shared Neighborhood Hits	652
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

OPTN_HUMAN
NC score	0.465359 (rank : 174)	θ value	1.09739e-05 (rank : 302)
Query Neighborhood Hits	1371	Target Neighborhood Hits	827	Shared Neighborhood Hits	552
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

CCD11_HUMAN
NC score	0.465294 (rank : 175)	θ value	0.125558 (rank : 806)
Query Neighborhood Hits	1371	Target Neighborhood Hits	822	Shared Neighborhood Hits	580
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

GOGA2_HUMAN
NC score	0.464409 (rank : 176)	θ value	0.00175202 (rank : 514)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	553
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

IF3A_HUMAN
NC score	0.463883 (rank : 177)	θ value	7.1131e-05 (rank : 383)
Query Neighborhood Hits	1371	Target Neighborhood Hits	875	Shared Neighborhood Hits	595
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

VINEX_MOUSE
NC score	0.463071 (rank : 178)	θ value	1.68911e-14 (rank : 53)
Query Neighborhood Hits	1371	Target Neighborhood Hits	286	Shared Neighborhood Hits	213
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

LRC45_HUMAN
NC score	0.463063 (rank : 179)	θ value	2.36792 (rank : 1146)
Query Neighborhood Hits	1371	Target Neighborhood Hits	933	Shared Neighborhood Hits	587
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

XE7_HUMAN
NC score	0.461377 (rank : 180)	θ value	0.163984 (rank : 839)
Query Neighborhood Hits	1371	Target Neighborhood Hits	738	Shared Neighborhood Hits	524
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ARHG1_HUMAN
NC score	0.461273 (rank : 181)	θ value	2.59989e-23 (rank : 10)
Query Neighborhood Hits	1371	Target Neighborhood Hits	176	Shared Neighborhood Hits	74
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

RFIP3_HUMAN
NC score	0.460555 (rank : 182)	θ value	1.87187e-05 (rank : 335)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1055	Shared Neighborhood Hits	596
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

GCC1_HUMAN
NC score	0.460056 (rank : 183)	θ value	0.00509761 (rank : 582)
Query Neighborhood Hits	1371	Target Neighborhood Hits	887	Shared Neighborhood Hits	571
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

SRBS1_MOUSE
NC score	0.458353 (rank : 184)	θ value	1.38178e-16 (rank : 37)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	232
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

GAS8_MOUSE
NC score	0.457530 (rank : 185)	θ value	0.00665767 (rank : 594)
Query Neighborhood Hits	1371	Target Neighborhood Hits	622	Shared Neighborhood Hits	484
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

SMC2_MOUSE
NC score	0.456987 (rank : 186)	θ value	0.0563607 (rank : 737)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1131	Shared Neighborhood Hits	676
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SM1L2_MOUSE
NC score	0.456722 (rank : 187)	θ value	8.40245e-06 (rank : 297)
Query Neighborhood Hits	1371	Target Neighborhood Hits	918	Shared Neighborhood Hits	588
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

OFD1_HUMAN
NC score	0.456670 (rank : 188)	θ value	0.00869519 (rank : 613)
Query Neighborhood Hits	1371	Target Neighborhood Hits	753	Shared Neighborhood Hits	520
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

SAS6_HUMAN
NC score	0.456618 (rank : 189)	θ value	0.0961366 (rank : 789)
Query Neighborhood Hits	1371	Target Neighborhood Hits	791	Shared Neighborhood Hits	541
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

CEP55_MOUSE
NC score	0.456363 (rank : 190)	θ value	0.00298849 (rank : 548)
Query Neighborhood Hits	1371	Target Neighborhood Hits	693	Shared Neighborhood Hits	511
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

NCK1_HUMAN
NC score	0.456362 (rank : 191)	θ value	2.69047e-20 (rank : 21)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	224
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

CT2NL_HUMAN
NC score	0.455244 (rank : 192)	θ value	8.40245e-06 (rank : 289)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1059	Shared Neighborhood Hits	613
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

LRRF2_HUMAN
NC score	0.455009 (rank : 193)	θ value	0.000786445 (rank : 485)
Query Neighborhood Hits	1371	Target Neighborhood Hits	791	Shared Neighborhood Hits	540
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

BICD1_MOUSE
NC score	0.454138 (rank : 194)	θ value	0.0563607 (rank : 723)
Query Neighborhood Hits	1371	Target Neighborhood Hits	837	Shared Neighborhood Hits	571
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CCHCR_HUMAN
NC score	0.454035 (rank : 195)	θ value	0.0961366 (rank : 776)
Query Neighborhood Hits	1371	Target Neighborhood Hits	717	Shared Neighborhood Hits	505
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

EVPL_HUMAN
NC score	0.453665 (rank : 196)	θ value	0.000121331 (rank : 394)
Query Neighborhood Hits	1371	Target Neighborhood Hits	895	Shared Neighborhood Hits	580
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

NCF2_HUMAN
NC score	0.453293 (rank : 197)	θ value	9.92553e-07 (rank : 225)
Query Neighborhood Hits	1371	Target Neighborhood Hits	229	Shared Neighborhood Hits	188
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

LIPA2_MOUSE
NC score	0.452903 (rank : 198)	θ value	1.99992e-07 (rank : 183)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1282	Shared Neighborhood Hits	723
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

ARHGB_HUMAN
NC score	0.452679 (rank : 199)	θ value	7.30988e-26 (rank : 7)
Query Neighborhood Hits	1371	Target Neighborhood Hits	375	Shared Neighborhood Hits	135
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

TUFT1_HUMAN
NC score	0.452350 (rank : 200)	θ value	0.0113563 (rank : 636)
Query Neighborhood Hits	1371	Target Neighborhood Hits	686	Shared Neighborhood Hits	494
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

RFIP4_HUMAN
NC score	0.452163 (rank : 201)	θ value	0.000121331 (rank : 402)
Query Neighborhood Hits	1371	Target Neighborhood Hits	785	Shared Neighborhood Hits	572
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

PREX1_HUMAN
NC score	0.451891 (rank : 202)	θ value	3.07829e-16 (rank : 38)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

GCC1_MOUSE
NC score	0.451630 (rank : 203)	θ value	0.0148317 (rank : 643)
Query Neighborhood Hits	1371	Target Neighborhood Hits	777	Shared Neighborhood Hits	518
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

TUFT1_MOUSE
NC score	0.451456 (rank : 204)	θ value	0.00298849 (rank : 561)
Query Neighborhood Hits	1371	Target Neighborhood Hits	732	Shared Neighborhood Hits	509
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

LIPA1_HUMAN
NC score	0.451336 (rank : 205)	θ value	5.44631e-05 (rank : 374)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1294	Shared Neighborhood Hits	718
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LUZP1_MOUSE
NC score	0.450328 (rank : 206)	θ value	0.00102713 (rank : 497)
Query Neighborhood Hits	1371	Target Neighborhood Hits	940	Shared Neighborhood Hits	570
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

BRE1A_HUMAN
NC score	0.450237 (rank : 207)	θ value	0.0113563 (rank : 619)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1071	Shared Neighborhood Hits	622
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

DYNA_HUMAN
NC score	0.450205 (rank : 208)	θ value	0.0563607 (rank : 728)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1194	Shared Neighborhood Hits	662
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

CNTRB_MOUSE
NC score	0.450099 (rank : 209)	θ value	0.00175202 (rank : 513)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1029	Shared Neighborhood Hits	588
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

NCK2_HUMAN
NC score	0.449943 (rank : 210)	θ value	2.13179e-17 (rank : 33)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	214
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

DYNA_MOUSE
NC score	0.448451 (rank : 211)	θ value	0.0330416 (rank : 696)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1084	Shared Neighborhood Hits	633
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

PPIP1_HUMAN
NC score	0.448146 (rank : 212)	θ value	3.77169e-06 (rank : 270)
Query Neighborhood Hits	1371	Target Neighborhood Hits	389	Shared Neighborhood Hits	353
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SMC4_HUMAN
NC score	0.448139 (rank : 213)	θ value	9.29e-05 (rank : 393)
Query Neighborhood Hits	1371	Target Neighborhood Hits	937	Shared Neighborhood Hits	596
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

INVO_HUMAN
NC score	0.448121 (rank : 214)	θ value	0.000602161 (rank : 467)
Query Neighborhood Hits	1371	Target Neighborhood Hits	636	Shared Neighborhood Hits	405
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

BICD1_HUMAN
NC score	0.447983 (rank : 215)	θ value	0.0563607 (rank : 722)
Query Neighborhood Hits	1371	Target Neighborhood Hits	844	Shared Neighborhood Hits	565
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD2_MOUSE
NC score	0.447976 (rank : 216)	θ value	0.00035302 (rank : 438)
Query Neighborhood Hits	1371	Target Neighborhood Hits	864	Shared Neighborhood Hits	560
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

ARHGC_HUMAN
NC score	0.447962 (rank : 217)	θ value	1.33217e-27 (rank : 6)
Query Neighborhood Hits	1371	Target Neighborhood Hits	351	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CCD62_HUMAN
NC score	0.447646 (rank : 218)	θ value	0.47712 (rank : 933)
Query Neighborhood Hits	1371	Target Neighborhood Hits	631	Shared Neighborhood Hits	463
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

BICD2_HUMAN
NC score	0.447556 (rank : 219)	θ value	1.43324e-05 (rank : 308)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	559
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

ANR26_HUMAN
NC score	0.447251 (rank : 220)	θ value	1.58096e-12 (rank : 75)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1614	Shared Neighborhood Hits	737
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

HIP1_HUMAN
NC score	0.447197 (rank : 221)	θ value	3.19293e-05 (rank : 351)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1016	Shared Neighborhood Hits	614
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

EVPL_MOUSE
NC score	0.446356 (rank : 222)	θ value	0.0252991 (rank : 677)
Query Neighborhood Hits	1371	Target Neighborhood Hits	952	Shared Neighborhood Hits	610
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

RRBP1_HUMAN
NC score	0.445928 (rank : 223)	θ value	4.92598e-06 (rank : 276)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1306	Shared Neighborhood Hits	646
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

HOOK2_MOUSE
NC score	0.445554 (rank : 224)	θ value	0.000158464 (rank : 411)
Query Neighborhood Hits	1371	Target Neighborhood Hits	736	Shared Neighborhood Hits	532
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

ARHGC_MOUSE
NC score	0.445007 (rank : 225)	θ value	4.57862e-28 (rank : 5)
Query Neighborhood Hits	1371	Target Neighborhood Hits	344	Shared Neighborhood Hits	147
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BRE1A_MOUSE
NC score	0.444932 (rank : 226)	θ value	0.279714 (rank : 874)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1025	Shared Neighborhood Hits	604
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

NAF1_MOUSE
NC score	0.444831 (rank : 227)	θ value	0.00134147 (rank : 505)
Query Neighborhood Hits	1371	Target Neighborhood Hits	852	Shared Neighborhood Hits	572
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCF1_MOUSE
NC score	0.444332 (rank : 228)	θ value	1.86753e-13 (rank : 61)
Query Neighborhood Hits	1371	Target Neighborhood Hits	198	Shared Neighborhood Hits	183
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

BRE1B_HUMAN
NC score	0.443518 (rank : 229)	θ value	2.36244e-08 (rank : 148)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1040	Shared Neighborhood Hits	576
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

SRBS1_HUMAN
NC score	0.443245 (rank : 230)	θ value	2.52405e-10 (rank : 112)
Query Neighborhood Hits	1371	Target Neighborhood Hits	396	Shared Neighborhood Hits	250
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ANR26_MOUSE
NC score	0.442607 (rank : 231)	θ value	5.81887e-07 (rank : 209)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1554	Shared Neighborhood Hits	722
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NAF1_HUMAN
NC score	0.442190 (rank : 232)	θ value	0.00665767 (rank : 597)
Query Neighborhood Hits	1371	Target Neighborhood Hits	937	Shared Neighborhood Hits	585
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

CCD91_HUMAN
NC score	0.441886 (rank : 233)	θ value	0.0431538 (rank : 706)
Query Neighborhood Hits	1371	Target Neighborhood Hits	868	Shared Neighborhood Hits	560
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CYTSA_MOUSE
NC score	0.441519 (rank : 234)	θ value	2.36792 (rank : 1131)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1104	Shared Neighborhood Hits	636
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

TIAM1_MOUSE
NC score	0.441303 (rank : 235)	θ value	7.32683e-18 (rank : 31)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	89
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

NCF1_HUMAN
NC score	0.440681 (rank : 236)	θ value	1.74796e-11 (rank : 94)
Query Neighborhood Hits	1371	Target Neighborhood Hits	198	Shared Neighborhood Hits	178
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NEMO_MOUSE
NC score	0.440448 (rank : 237)	θ value	0.00665767 (rank : 598)
Query Neighborhood Hits	1371	Target Neighborhood Hits	658	Shared Neighborhood Hits	489
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

ARHG1_MOUSE
NC score	0.439738 (rank : 238)	θ value	6.84181e-24 (rank : 9)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	85
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CCD91_MOUSE
NC score	0.439547 (rank : 239)	θ value	0.00665767 (rank : 591)
Query Neighborhood Hits	1371	Target Neighborhood Hits	699	Shared Neighborhood Hits	490
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

ARHG2_MOUSE
NC score	0.439396 (rank : 240)	θ value	3.40345e-15 (rank : 44)
Query Neighborhood Hits	1371	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

NEBL_HUMAN
NC score	0.438100 (rank : 241)	θ value	8.40245e-06 (rank : 292)
Query Neighborhood Hits	1371	Target Neighborhood Hits	457	Shared Neighborhood Hits	370
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

KNTC2_HUMAN
NC score	0.437636 (rank : 242)	θ value	0.0252991 (rank : 680)
Query Neighborhood Hits	1371	Target Neighborhood Hits	673	Shared Neighborhood Hits	483
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

LIPA2_HUMAN
NC score	0.437501 (rank : 243)	θ value	0.00228821 (rank : 534)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1044	Shared Neighborhood Hits	658
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TIAM1_HUMAN
NC score	0.436694 (rank : 244)	θ value	1.99529e-15 (rank : 43)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	100
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ECT2_MOUSE
NC score	0.436658 (rank : 245)	θ value	2.79066e-09 (rank : 124)
Query Neighborhood Hits	1371	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

CYTSA_HUMAN
NC score	0.436395 (rank : 246)	θ value	2.36792 (rank : 1130)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1138	Shared Neighborhood Hits	639
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CUTL1_MOUSE
NC score	0.435849 (rank : 247)	θ value	4.0297e-08 (rank : 159)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1620	Shared Neighborhood Hits	678
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

PPIP1_MOUSE
NC score	0.435635 (rank : 248)	θ value	2.88788e-06 (rank : 261)
Query Neighborhood Hits	1371	Target Neighborhood Hits	377	Shared Neighborhood Hits	344
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

ZN291_HUMAN
NC score	0.435506 (rank : 249)	θ value	0.000270298 (rank : 436)
Query Neighborhood Hits	1371	Target Neighborhood Hits	647	Shared Neighborhood Hits	465
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

CUTL1_HUMAN
NC score	0.435273 (rank : 250)	θ value	5.26297e-08 (rank : 166)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1574	Shared Neighborhood Hits	684
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

RFIP4_MOUSE
NC score	0.435076 (rank : 251)	θ value	0.000602161 (rank : 470)
Query Neighborhood Hits	1371	Target Neighborhood Hits	708	Shared Neighborhood Hits	526
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CCD96_MOUSE
NC score	0.434729 (rank : 252)	θ value	5.44631e-05 (rank : 369)
Query Neighborhood Hits	1371	Target Neighborhood Hits	704	Shared Neighborhood Hits	454
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

MYH11_HUMAN
NC score	0.434602 (rank : 253)	θ value	2.21117e-06 (rank : 248)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1806	Shared Neighborhood Hits	836
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PKHG1_HUMAN
NC score	0.434503 (rank : 254)	θ value	2.52405e-10 (rank : 110)
Query Neighborhood Hits	1371	Target Neighborhood Hits	174	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

TSC1_HUMAN
NC score	0.434140 (rank : 255)	θ value	0.00390308 (rank : 576)
Query Neighborhood Hits	1371	Target Neighborhood Hits	765	Shared Neighborhood Hits	466
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

RRBP1_MOUSE
NC score	0.433936 (rank : 256)	θ value	1.38499e-08 (rank : 143)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1650	Shared Neighborhood Hits	718
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RUFY1_HUMAN
NC score	0.433681 (rank : 257)	θ value	0.000602161 (rank : 472)
Query Neighborhood Hits	1371	Target Neighborhood Hits	848	Shared Neighborhood Hits	552
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

LUZP1_HUMAN
NC score	0.432948 (rank : 258)	θ value	0.00390308 (rank : 568)
Query Neighborhood Hits	1371	Target Neighborhood Hits	739	Shared Neighborhood Hits	486
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

GRB2_HUMAN
NC score	0.432821 (rank : 259)	θ value	7.84624e-12 (rank : 86)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	231
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

CARD9_HUMAN
NC score	0.432808 (rank : 260)	θ value	0.00035302 (rank : 440)
Query Neighborhood Hits	1371	Target Neighborhood Hits	602	Shared Neighborhood Hits	471
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

GRB2_MOUSE
NC score	0.432512 (rank : 261)	θ value	7.84624e-12 (rank : 87)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	231
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

KNTC2_MOUSE
NC score	0.432310 (rank : 262)	θ value	0.62314 (rank : 965)
Query Neighborhood Hits	1371	Target Neighborhood Hits	692	Shared Neighborhood Hits	479
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

MYH11_MOUSE
NC score	0.432131 (rank : 263)	θ value	1.43324e-05 (rank : 317)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1777	Shared Neighborhood Hits	829
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

HIP1R_MOUSE
NC score	0.431769 (rank : 264)	θ value	0.0148317 (rank : 644)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	591
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

MYH9_HUMAN
NC score	0.430795 (rank : 265)	θ value	1.87187e-05 (rank : 331)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1762	Shared Neighborhood Hits	827
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TPM3_HUMAN
NC score	0.430779 (rank : 266)	θ value	0.00134147 (rank : 509)
Query Neighborhood Hits	1371	Target Neighborhood Hits	689	Shared Neighborhood Hits	486
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

UACA_MOUSE
NC score	0.430545 (rank : 267)	θ value	4.92598e-06 (rank : 283)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1620	Shared Neighborhood Hits	743
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

HAPIP_HUMAN
NC score	0.430379 (rank : 268)	θ value	1.38499e-08 (rank : 140)
Query Neighborhood Hits	1371	Target Neighborhood Hits	350	Shared Neighborhood Hits	250
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

ARHGF_HUMAN
NC score	0.430368 (rank : 269)	θ value	1.86753e-13 (rank : 60)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	85
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

NUF2_HUMAN
NC score	0.430248 (rank : 270)	θ value	0.0252991 (rank : 685)
Query Neighborhood Hits	1371	Target Neighborhood Hits	661	Shared Neighborhood Hits	461
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

MYH9_MOUSE
NC score	0.429821 (rank : 271)	θ value	2.44474e-05 (rank : 343)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1829	Shared Neighborhood Hits	836
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TPM3_MOUSE
NC score	0.429511 (rank : 272)	θ value	0.000602161 (rank : 473)
Query Neighborhood Hits	1371	Target Neighborhood Hits	676	Shared Neighborhood Hits	483
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

MYH3_HUMAN
NC score	0.428704 (rank : 273)	θ value	6.87365e-08 (rank : 171)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1660	Shared Neighborhood Hits	814
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

HOOK2_HUMAN
NC score	0.428527 (rank : 274)	θ value	0.00035302 (rank : 445)
Query Neighborhood Hits	1371	Target Neighborhood Hits	714	Shared Neighborhood Hits	503
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

TPM1_MOUSE
NC score	0.427714 (rank : 275)	θ value	0.00228821 (rank : 541)
Query Neighborhood Hits	1371	Target Neighborhood Hits	729	Shared Neighborhood Hits	523
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

SPTA2_HUMAN
NC score	0.427297 (rank : 276)	θ value	2.88788e-06 (rank : 262)
Query Neighborhood Hits	1371	Target Neighborhood Hits	888	Shared Neighborhood Hits	619
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ECT2_HUMAN
NC score	0.426057 (rank : 277)	θ value	2.36244e-08 (rank : 151)
Query Neighborhood Hits	1371	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

TPM4_MOUSE
NC score	0.425821 (rank : 278)	θ value	0.00228821 (rank : 542)
Query Neighborhood Hits	1371	Target Neighborhood Hits	703	Shared Neighborhood Hits	514
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

SMC4_MOUSE
NC score	0.425515 (rank : 279)	θ value	1.43324e-05 (rank : 322)
Query Neighborhood Hits	1371	Target Neighborhood Hits	830	Shared Neighborhood Hits	532
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

MYH10_HUMAN
NC score	0.425485 (rank : 280)	θ value	3.19293e-05 (rank : 352)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1620	Shared Neighborhood Hits	810
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.425461 (rank : 281)	θ value	3.19293e-05 (rank : 353)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1612	Shared Neighborhood Hits	805
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

LBC_HUMAN
NC score	0.425218 (rank : 282)	θ value	3.52202e-12 (rank : 81)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	72
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

CCD11_MOUSE
NC score	0.424759 (rank : 283)	θ value	θ > 10 (rank : 1474)
Query Neighborhood Hits	1371	Target Neighborhood Hits	498	Shared Neighborhood Hits	399
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

TNIP3_HUMAN
NC score	0.424485 (rank : 284)	θ value	3.0926 (rank : 1187)
Query Neighborhood Hits	1371	Target Neighborhood Hits	511	Shared Neighborhood Hits	402
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

ABI2_MOUSE
NC score	0.423948 (rank : 285)	θ value	6.64225e-11 (rank : 101)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	204
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

TPM1_HUMAN
NC score	0.423777 (rank : 286)	θ value	0.00228821 (rank : 540)
Query Neighborhood Hits	1371	Target Neighborhood Hits	716	Shared Neighborhood Hits	512
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

MYH8_HUMAN
NC score	0.423655 (rank : 287)	θ value	2.88788e-06 (rank : 258)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1610	Shared Neighborhood Hits	804
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CTGE5_MOUSE
NC score	0.423476 (rank : 288)	θ value	0.0736092 (rank : 752)
Query Neighborhood Hits	1371	Target Neighborhood Hits	928	Shared Neighborhood Hits	586
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

ARHGA_HUMAN
NC score	0.423464 (rank : 289)	θ value	7.58209e-15 (rank : 47)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	115
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

GRAP_MOUSE
NC score	0.423109 (rank : 290)	θ value	6.00763e-12 (rank : 85)
Query Neighborhood Hits	1371	Target Neighborhood Hits	309	Shared Neighborhood Hits	230
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

CT2NL_MOUSE
NC score	0.422924 (rank : 291)	θ value	0.0193708 (rank : 659)
Query Neighborhood Hits	1371	Target Neighborhood Hits	902	Shared Neighborhood Hits	562
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

GOG8A_HUMAN
NC score	0.422026 (rank : 292)	θ value	0.163984 (rank : 829)
Query Neighborhood Hits	1371	Target Neighborhood Hits	635	Shared Neighborhood Hits	463
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

MYH8_MOUSE
NC score	0.421728 (rank : 293)	θ value	3.77169e-06 (rank : 268)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1600	Shared Neighborhood Hits	793
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

GRAP_HUMAN
NC score	0.421585 (rank : 294)	θ value	2.0648e-12 (rank : 77)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	231
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

ARHG2_HUMAN
NC score	0.421538 (rank : 295)	θ value	5.8054e-15 (rank : 45)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	95
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

TPM2_HUMAN
NC score	0.421501 (rank : 296)	θ value	0.00869519 (rank : 617)
Query Neighborhood Hits	1371	Target Neighborhood Hits	677	Shared Neighborhood Hits	477
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

RUFY2_MOUSE
NC score	0.420697 (rank : 297)	θ value	0.0193708 (rank : 670)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	544
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

BRE1B_MOUSE
NC score	0.420159 (rank : 298)	θ value	2.36792 (rank : 1122)
Query Neighborhood Hits	1371	Target Neighborhood Hits	970	Shared Neighborhood Hits	566
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

MCF2L_MOUSE
NC score	0.420114 (rank : 299)	θ value	1.99992e-07 (rank : 184)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	188
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

ABI2_HUMAN
NC score	0.420065 (rank : 300)	θ value	6.64225e-11 (rank : 100)
Query Neighborhood Hits	1371	Target Neighborhood Hits	350	Shared Neighborhood Hits	210
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CR034_MOUSE
NC score	0.419906 (rank : 301)	θ value	0.000786445 (rank : 479)
Query Neighborhood Hits	1371	Target Neighborhood Hits	643	Shared Neighborhood Hits	466
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

TPM2_MOUSE
NC score	0.419036 (rank : 302)	θ value	0.0113563 (rank : 635)
Query Neighborhood Hits	1371	Target Neighborhood Hits	676	Shared Neighborhood Hits	476
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

FGD3_MOUSE
NC score	0.418458 (rank : 303)	θ value	9.26847e-13 (rank : 73)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	96
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

MYH13_HUMAN
NC score	0.418335 (rank : 304)	θ value	0.000786445 (rank : 488)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1504	Shared Neighborhood Hits	758
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

FGD4_HUMAN
NC score	0.417585 (rank : 305)	θ value	1.99529e-15 (rank : 42)
Query Neighborhood Hits	1371	Target Neighborhood Hits	219	Shared Neighborhood Hits	111
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

RUFY1_MOUSE
NC score	0.417269 (rank : 306)	θ value	0.000461057 (rank : 460)
Query Neighborhood Hits	1371	Target Neighborhood Hits	765	Shared Neighborhood Hits	494
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

PLEC1_HUMAN
NC score	0.417077 (rank : 307)	θ value	0.000158464 (rank : 413)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1326	Shared Neighborhood Hits	702
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MYH6_MOUSE
NC score	0.416237 (rank : 308)	θ value	5.81887e-07 (rank : 211)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1501	Shared Neighborhood Hits	766
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH1_HUMAN
NC score	0.416084 (rank : 309)	θ value	1.43324e-05 (rank : 318)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1478	Shared Neighborhood Hits	768
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH2_HUMAN
NC score	0.415962 (rank : 310)	θ value	3.41135e-07 (rank : 195)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1491	Shared Neighborhood Hits	766
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

UACA_HUMAN
NC score	0.415929 (rank : 311)	θ value	0.00102713 (rank : 501)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1622	Shared Neighborhood Hits	734
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

C102B_HUMAN
NC score	0.415679 (rank : 312)	θ value	0.0736092 (rank : 745)
Query Neighborhood Hits	1371	Target Neighborhood Hits	542	Shared Neighborhood Hits	409
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

MYH1_MOUSE
NC score	0.415367 (rank : 313)	θ value	2.21117e-06 (rank : 249)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1461	Shared Neighborhood Hits	763
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

FGD4_MOUSE
NC score	0.415212 (rank : 314)	θ value	2.43908e-13 (rank : 63)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	111
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

MYH7_HUMAN
NC score	0.415044 (rank : 315)	θ value	8.40245e-06 (rank : 291)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1559	Shared Neighborhood Hits	775
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

HIP1R_HUMAN
NC score	0.414573 (rank : 316)	θ value	0.365318 (rank : 908)
Query Neighborhood Hits	1371	Target Neighborhood Hits	809	Shared Neighborhood Hits	539
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

GRAP2_MOUSE
NC score	0.414548 (rank : 317)	θ value	2.36244e-08 (rank : 152)
Query Neighborhood Hits	1371	Target Neighborhood Hits	297	Shared Neighborhood Hits	221
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

MYH6_HUMAN
NC score	0.414181 (rank : 318)	θ value	4.1701e-05 (rank : 364)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1426	Shared Neighborhood Hits	748
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CNTRB_HUMAN
NC score	0.414115 (rank : 319)	θ value	0.47712 (rank : 936)
Query Neighborhood Hits	1371	Target Neighborhood Hits	690	Shared Neighborhood Hits	469
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

TEX9_MOUSE
NC score	0.413814 (rank : 320)	θ value	0.0113563 (rank : 634)
Query Neighborhood Hits	1371	Target Neighborhood Hits	581	Shared Neighborhood Hits	455
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

CCD27_HUMAN
NC score	0.412635 (rank : 321)	θ value	0.000270298 (rank : 426)
Query Neighborhood Hits	1371	Target Neighborhood Hits	594	Shared Neighborhood Hits	420
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

MYH4_MOUSE
NC score	0.411795 (rank : 322)	θ value	7.1131e-05 (rank : 384)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1476	Shared Neighborhood Hits	758
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

TXLNA_MOUSE
NC score	0.411297 (rank : 323)	θ value	0.00020696 (rank : 424)
Query Neighborhood Hits	1371	Target Neighborhood Hits	846	Shared Neighborhood Hits	552
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

GRAP2_HUMAN
NC score	0.410815 (rank : 324)	θ value	5.26297e-08 (rank : 167)
Query Neighborhood Hits	1371	Target Neighborhood Hits	304	Shared Neighborhood Hits	226
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

HOME2_MOUSE
NC score	0.410236 (rank : 325)	θ value	1.43324e-05 (rank : 315)
Query Neighborhood Hits	1371	Target Neighborhood Hits	882	Shared Neighborhood Hits	569
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

NUF2_MOUSE
NC score	0.410015 (rank : 326)	θ value	0.0252991 (rank : 686)
Query Neighborhood Hits	1371	Target Neighborhood Hits	585	Shared Neighborhood Hits	430
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

STAM1_MOUSE
NC score	0.409097 (rank : 327)	θ value	1.02475e-11 (rank : 90)
Query Neighborhood Hits	1371	Target Neighborhood Hits	273	Shared Neighborhood Hits	217
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TRAK1_HUMAN
NC score	0.407811 (rank : 328)	θ value	0.0563607 (rank : 740)
Query Neighborhood Hits	1371	Target Neighborhood Hits	660	Shared Neighborhood Hits	466
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

PHLB2_MOUSE
NC score	0.407687 (rank : 329)	θ value	9.29e-05 (rank : 392)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1016	Shared Neighborhood Hits	601
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

ABI1_MOUSE
NC score	0.407600 (rank : 330)	θ value	1.63604e-09 (rank : 119)
Query Neighborhood Hits	1371	Target Neighborhood Hits	246	Shared Neighborhood Hits	189
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

STAM1_HUMAN
NC score	0.407386 (rank : 331)	θ value	8.67504e-11 (rank : 104)
Query Neighborhood Hits	1371	Target Neighborhood Hits	271	Shared Neighborhood Hits	223
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

SYNE1_HUMAN
NC score	0.407137 (rank : 332)	θ value	4.1701e-05 (rank : 367)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1484	Shared Neighborhood Hits	692
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

FGD2_HUMAN
NC score	0.407133 (rank : 333)	θ value	7.09661e-13 (rank : 69)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

ARHGA_MOUSE
NC score	0.406665 (rank : 334)	θ value	7.58209e-15 (rank : 48)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	84
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

MACOI_HUMAN
NC score	0.406546 (rank : 335)	θ value	0.0148317 (rank : 645)
Query Neighborhood Hits	1371	Target Neighborhood Hits	650	Shared Neighborhood Hits	456
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

CAR11_HUMAN
NC score	0.406328 (rank : 336)	θ value	0.00035302 (rank : 439)
Query Neighborhood Hits	1371	Target Neighborhood Hits	690	Shared Neighborhood Hits	505
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

FGD2_MOUSE
NC score	0.406314 (rank : 337)	θ value	2.0648e-12 (rank : 76)
Query Neighborhood Hits	1371	Target Neighborhood Hits	163	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

LZTS1_MOUSE
NC score	0.406060 (rank : 338)	θ value	1.69304e-06 (rank : 239)
Query Neighborhood Hits	1371	Target Neighborhood Hits	540	Shared Neighborhood Hits	395
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MACOI_MOUSE
NC score	0.405481 (rank : 339)	θ value	0.21417 (rank : 849)
Query Neighborhood Hits	1371	Target Neighborhood Hits	620	Shared Neighborhood Hits	448
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

CEP55_HUMAN
NC score	0.405447 (rank : 340)	θ value	θ > 10 (rank : 1507)
Query Neighborhood Hits	1371	Target Neighborhood Hits	504	Shared Neighborhood Hits	394
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

LZTS1_HUMAN
NC score	0.405177 (rank : 341)	θ value	1.87187e-05 (rank : 330)
Query Neighborhood Hits	1371	Target Neighborhood Hits	532	Shared Neighborhood Hits	397
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

TRAIP_MOUSE
NC score	0.405015 (rank : 342)	θ value	0.163984 (rank : 836)
Query Neighborhood Hits	1371	Target Neighborhood Hits	745	Shared Neighborhood Hits	450
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

MYH4_HUMAN
NC score	0.404922 (rank : 343)	θ value	0.000270298 (rank : 429)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1377	Shared Neighborhood Hits	731
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

SRC8_HUMAN
NC score	0.404344 (rank : 344)	θ value	5.81887e-07 (rank : 214)
Query Neighborhood Hits	1371	Target Neighborhood Hits	269	Shared Neighborhood Hits	215
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

STAM2_MOUSE
NC score	0.404139 (rank : 345)	θ value	8.67504e-11 (rank : 105)
Query Neighborhood Hits	1371	Target Neighborhood Hits	285	Shared Neighborhood Hits	224
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

CCD96_HUMAN
NC score	0.403933 (rank : 346)	θ value	1.17247e-07 (rank : 176)
Query Neighborhood Hits	1371	Target Neighborhood Hits	595	Shared Neighborhood Hits	372
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

HCLS1_MOUSE
NC score	0.403431 (rank : 347)	θ value	1.17247e-07 (rank : 177)
Query Neighborhood Hits	1371	Target Neighborhood Hits	329	Shared Neighborhood Hits	198
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

SH3G2_HUMAN
NC score	0.402978 (rank : 348)	θ value	1.53129e-07 (rank : 180)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	291
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

KINH_HUMAN
NC score	0.402372 (rank : 349)	θ value	4.92598e-06 (rank : 274)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1231	Shared Neighborhood Hits	705
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

PHLB2_HUMAN
NC score	0.402309 (rank : 350)	θ value	0.00175202 (rank : 521)
Query Neighborhood Hits	1371	Target Neighborhood Hits	964	Shared Neighborhood Hits	578
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

MY18B_HUMAN
NC score	0.401808 (rank : 351)	θ value	0.00298849 (rank : 555)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1299	Shared Neighborhood Hits	610
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

TRAIP_HUMAN
NC score	0.401623 (rank : 352)	θ value	0.00390308 (rank : 575)
Query Neighborhood Hits	1371	Target Neighborhood Hits	780	Shared Neighborhood Hits	461
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

LRRF2_MOUSE
NC score	0.400907 (rank : 353)	θ value	0.21417 (rank : 848)
Query Neighborhood Hits	1371	Target Neighborhood Hits	556	Shared Neighborhood Hits	406
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

FGD3_HUMAN
NC score	0.400894 (rank : 354)	θ value	3.18553e-13 (rank : 64)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	88
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

SPAG5_MOUSE
NC score	0.400882 (rank : 355)	θ value	1.81305 (rank : 1110)
Query Neighborhood Hits	1371	Target Neighborhood Hits	612	Shared Neighborhood Hits	432
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

HCLS1_HUMAN
NC score	0.400861 (rank : 356)	θ value	2.61198e-07 (rank : 189)
Query Neighborhood Hits	1371	Target Neighborhood Hits	358	Shared Neighborhood Hits	203
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

SRC8_MOUSE
NC score	0.400526 (rank : 357)	θ value	4.45536e-07 (rank : 205)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	210
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

TPM4_HUMAN
NC score	0.400109 (rank : 358)	θ value	0.000786445 (rank : 491)
Query Neighborhood Hits	1371	Target Neighborhood Hits	525	Shared Neighborhood Hits	405
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

CCD27_MOUSE
NC score	0.399462 (rank : 359)	θ value	0.0193708 (rank : 657)
Query Neighborhood Hits	1371	Target Neighborhood Hits	461	Shared Neighborhood Hits	357
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CF152_HUMAN
NC score	0.399272 (rank : 360)	θ value	1.38821 (rank : 1047)
Query Neighborhood Hits	1371	Target Neighborhood Hits	704	Shared Neighborhood Hits	484
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

RBM25_HUMAN
NC score	0.398526 (rank : 361)	θ value	5.27518 (rank : 1260)
Query Neighborhood Hits	1371	Target Neighborhood Hits	682	Shared Neighborhood Hits	420
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

MCF2_HUMAN
NC score	0.398219 (rank : 362)	θ value	5.81887e-07 (rank : 210)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	137
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

DLG5_HUMAN
NC score	0.398164 (rank : 363)	θ value	0.00035302 (rank : 442)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1088	Shared Neighborhood Hits	596
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

STAM2_HUMAN
NC score	0.397969 (rank : 364)	θ value	8.11959e-09 (rank : 134)
Query Neighborhood Hits	1371	Target Neighborhood Hits	288	Shared Neighborhood Hits	232
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

SH3G2_MOUSE
NC score	0.397396 (rank : 365)	θ value	5.81887e-07 (rank : 213)
Query Neighborhood Hits	1371	Target Neighborhood Hits	319	Shared Neighborhood Hits	284
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

MYH14_MOUSE
NC score	0.396915 (rank : 366)	θ value	0.00228821 (rank : 536)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1225	Shared Neighborhood Hits	699
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CAF1A_MOUSE
NC score	0.396506 (rank : 367)	θ value	0.000786445 (rank : 476)
Query Neighborhood Hits	1371	Target Neighborhood Hits	736	Shared Neighborhood Hits	499
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CR034_HUMAN
NC score	0.396143 (rank : 368)	θ value	2.36792 (rank : 1129)
Query Neighborhood Hits	1371	Target Neighborhood Hits	538	Shared Neighborhood Hits	405
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CTGE5_HUMAN
NC score	0.396027 (rank : 369)	θ value	0.0113563 (rank : 620)
Query Neighborhood Hits	1371	Target Neighborhood Hits	800	Shared Neighborhood Hits	537
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

TXLNA_HUMAN
NC score	0.395256 (rank : 370)	θ value	0.00020696 (rank : 423)
Query Neighborhood Hits	1371	Target Neighborhood Hits	982	Shared Neighborhood Hits	546
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

NDE1_HUMAN
NC score	0.394999 (rank : 371)	θ value	0.62314 (rank : 971)
Query Neighborhood Hits	1371	Target Neighborhood Hits	823	Shared Neighborhood Hits	551
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

SPTA1_HUMAN
NC score	0.394844 (rank : 372)	θ value	0.000786445 (rank : 490)
Query Neighborhood Hits	1371	Target Neighborhood Hits	748	Shared Neighborhood Hits	564
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CKAP4_MOUSE
NC score	0.394184 (rank : 373)	θ value	θ > 10 (rank : 1525)
Query Neighborhood Hits	1371	Target Neighborhood Hits	596	Shared Neighborhood Hits	412
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

ABI1_HUMAN
NC score	0.393961 (rank : 374)	θ value	1.63604e-09 (rank : 118)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	185
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

MYO5C_HUMAN
NC score	0.393859 (rank : 375)	θ value	3.08544e-08 (rank : 157)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1206	Shared Neighborhood Hits	691
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

STAC_HUMAN
NC score	0.393850 (rank : 376)	θ value	0.00035302 (rank : 450)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	209
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CRCM_HUMAN
NC score	0.392940 (rank : 377)	θ value	0.0961366 (rank : 778)
Query Neighborhood Hits	1371	Target Neighborhood Hits	520	Shared Neighborhood Hits	396
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

NCF4_MOUSE
NC score	0.392491 (rank : 378)	θ value	2.21117e-06 (rank : 250)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	151
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

TEX9_HUMAN
NC score	0.392223 (rank : 379)	θ value	0.0431538 (rank : 718)
Query Neighborhood Hits	1371	Target Neighborhood Hits	541	Shared Neighborhood Hits	405
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

SH3G1_HUMAN
NC score	0.391995 (rank : 380)	θ value	8.40245e-06 (rank : 296)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	279
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

MACF4_HUMAN
NC score	0.391354 (rank : 381)	θ value	0.0113563 (rank : 626)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1321	Shared Neighborhood Hits	653
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SH3G3_MOUSE
NC score	0.390899 (rank : 382)	θ value	9.92553e-07 (rank : 229)
Query Neighborhood Hits	1371	Target Neighborhood Hits	236	Shared Neighborhood Hits	220
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SPAG5_HUMAN
NC score	0.390579 (rank : 383)	θ value	0.279714 (rank : 891)
Query Neighborhood Hits	1371	Target Neighborhood Hits	625	Shared Neighborhood Hits	446
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

RABE2_MOUSE
NC score	0.390416 (rank : 384)	θ value	4.03905 (rank : 1220)
Query Neighborhood Hits	1371	Target Neighborhood Hits	598	Shared Neighborhood Hits	436
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

MIPO1_HUMAN
NC score	0.388935 (rank : 385)	θ value	6.88961 (rank : 1304)
Query Neighborhood Hits	1371	Target Neighborhood Hits	486	Shared Neighborhood Hits	380
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

BPAEA_HUMAN
NC score	0.387939 (rank : 386)	θ value	0.0563607 (rank : 724)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1369	Shared Neighborhood Hits	682
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

T3JAM_HUMAN
NC score	0.387905 (rank : 387)	θ value	0.0252991 (rank : 693)
Query Neighborhood Hits	1371	Target Neighborhood Hits	533	Shared Neighborhood Hits	400
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

CCD93_HUMAN
NC score	0.387425 (rank : 388)	θ value	0.00509761 (rank : 579)
Query Neighborhood Hits	1371	Target Neighborhood Hits	600	Shared Neighborhood Hits	436
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

STAC_MOUSE
NC score	0.387294 (rank : 389)	θ value	0.000270298 (rank : 435)
Query Neighborhood Hits	1371	Target Neighborhood Hits	268	Shared Neighborhood Hits	203
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

KIF4A_HUMAN
NC score	0.387022 (rank : 390)	θ value	2.61198e-07 (rank : 191)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1159	Shared Neighborhood Hits	663
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

SH3G1_MOUSE
NC score	0.386979 (rank : 391)	θ value	3.77169e-06 (rank : 271)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	261
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

CKAP4_HUMAN
NC score	0.386067 (rank : 392)	θ value	5.27518 (rank : 1238)
Query Neighborhood Hits	1371	Target Neighborhood Hits	592	Shared Neighborhood Hits	400
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CF182_MOUSE
NC score	0.385986 (rank : 393)	θ value	0.00869519 (rank : 604)
Query Neighborhood Hits	1371	Target Neighborhood Hits	551	Shared Neighborhood Hits	396
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

MPP9_HUMAN
NC score	0.385467 (rank : 394)	θ value	0.125558 (rank : 813)
Query Neighborhood Hits	1371	Target Neighborhood Hits	529	Shared Neighborhood Hits	386
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

VDP_HUMAN
NC score	0.384772 (rank : 395)	θ value	0.0736092 (rank : 770)
Query Neighborhood Hits	1371	Target Neighborhood Hits	645	Shared Neighborhood Hits	425
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

RPGR1_HUMAN
NC score	0.384487 (rank : 396)	θ value	0.0563607 (rank : 734)
Query Neighborhood Hits	1371	Target Neighborhood Hits	578	Shared Neighborhood Hits	403
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

KINH_MOUSE
NC score	0.382838 (rank : 397)	θ value	9.29e-05 (rank : 388)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1082	Shared Neighborhood Hits	663
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

PACN2_MOUSE
NC score	0.382550 (rank : 398)	θ value	6.43352e-06 (rank : 286)
Query Neighborhood Hits	1371	Target Neighborhood Hits	382	Shared Neighborhood Hits	311
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

LIPA3_HUMAN
NC score	0.382459 (rank : 399)	θ value	1.81305 (rank : 1097)
Query Neighborhood Hits	1371	Target Neighborhood Hits	828	Shared Neighborhood Hits	537
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

RUFY3_HUMAN
NC score	0.381901 (rank : 400)	θ value	0.0148317 (rank : 651)
Query Neighborhood Hits	1371	Target Neighborhood Hits	594	Shared Neighborhood Hits	463
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

CEP57_HUMAN
NC score	0.381548 (rank : 401)	θ value	1.38821 (rank : 1044)
Query Neighborhood Hits	1371	Target Neighborhood Hits	576	Shared Neighborhood Hits	437
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

SYNE2_HUMAN
NC score	0.381511 (rank : 402)	θ value	0.0148317 (rank : 653)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1323	Shared Neighborhood Hits	666
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

FGD1_HUMAN
NC score	0.381377 (rank : 403)	θ value	8.67504e-11 (rank : 102)
Query Neighborhood Hits	1371	Target Neighborhood Hits	367	Shared Neighborhood Hits	114
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

NCF4_HUMAN
NC score	0.380975 (rank : 404)	θ value	2.88788e-06 (rank : 259)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	136
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

FGD1_MOUSE
NC score	0.380571 (rank : 405)	θ value	1.133e-10 (rank : 108)
Query Neighborhood Hits	1371	Target Neighborhood Hits	387	Shared Neighborhood Hits	106
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CEP57_MOUSE
NC score	0.379500 (rank : 406)	θ value	1.81305 (rank : 1082)
Query Neighborhood Hits	1371	Target Neighborhood Hits	580	Shared Neighborhood Hits	440
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CA065_HUMAN
NC score	0.378961 (rank : 407)	θ value	0.0563607 (rank : 725)
Query Neighborhood Hits	1371	Target Neighborhood Hits	469	Shared Neighborhood Hits	353
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

PACN2_HUMAN
NC score	0.378308 (rank : 408)	θ value	1.09739e-05 (rank : 303)
Query Neighborhood Hits	1371	Target Neighborhood Hits	339	Shared Neighborhood Hits	290
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

DMD_MOUSE
NC score	0.377655 (rank : 409)	θ value	0.000602161 (rank : 463)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1111	Shared Neighborhood Hits	627
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

RUFY3_MOUSE
NC score	0.377522 (rank : 410)	θ value	0.00665767 (rank : 599)
Query Neighborhood Hits	1371	Target Neighborhood Hits	579	Shared Neighborhood Hits	456
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

STAC3_MOUSE
NC score	0.377438 (rank : 411)	θ value	3.08544e-08 (rank : 158)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	180
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

RAI14_MOUSE
NC score	0.375169 (rank : 412)	θ value	1.09739e-05 (rank : 304)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1505	Shared Neighborhood Hits	674
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SH3G3_HUMAN
NC score	0.374041 (rank : 413)	θ value	3.77169e-06 (rank : 272)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	205
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

STAC3_HUMAN
NC score	0.373748 (rank : 414)	θ value	1.38499e-08 (rank : 144)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	174
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

MYH14_HUMAN
NC score	0.372332 (rank : 415)	θ value	0.00390308 (rank : 569)
Query Neighborhood Hits	1371	Target Neighborhood Hits	995	Shared Neighborhood Hits	600
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

BPA1_MOUSE
NC score	0.372155 (rank : 416)	θ value	1.09739e-05 (rank : 298)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1477	Shared Neighborhood Hits	685
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DMD_HUMAN
NC score	0.372082 (rank : 417)	θ value	3.19293e-05 (rank : 349)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1135	Shared Neighborhood Hits	621
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

KIF5C_MOUSE
NC score	0.370882 (rank : 418)	θ value	0.000786445 (rank : 483)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1040	Shared Neighborhood Hits	662
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CRKL_HUMAN
NC score	0.370146 (rank : 419)	θ value	6.43352e-06 (rank : 284)
Query Neighborhood Hits	1371	Target Neighborhood Hits	313	Shared Neighborhood Hits	221
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

NEST_HUMAN
NC score	0.369811 (rank : 420)	θ value	6.88961 (rank : 1307)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1305	Shared Neighborhood Hits	572
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CAF1A_HUMAN
NC score	0.369367 (rank : 421)	θ value	0.0961366 (rank : 775)
Query Neighborhood Hits	1371	Target Neighborhood Hits	750	Shared Neighborhood Hits	484
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ZWINT_MOUSE
NC score	0.369097 (rank : 422)	θ value	0.00869519 (rank : 618)
Query Neighborhood Hits	1371	Target Neighborhood Hits	497	Shared Neighborhood Hits	384
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

FGD6_MOUSE
NC score	0.368921 (rank : 423)	θ value	4.02038e-16 (rank : 39)
Query Neighborhood Hits	1371	Target Neighborhood Hits	282	Shared Neighborhood Hits	112
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

CENPJ_HUMAN
NC score	0.368830 (rank : 424)	θ value	0.0431538 (rank : 707)
Query Neighborhood Hits	1371	Target Neighborhood Hits	721	Shared Neighborhood Hits	469
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

LIPB1_MOUSE
NC score	0.368660 (rank : 425)	θ value	0.00869519 (rank : 610)
Query Neighborhood Hits	1371	Target Neighborhood Hits	727	Shared Neighborhood Hits	496
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

SPTA1_MOUSE
NC score	0.368567 (rank : 426)	θ value	0.00102713 (rank : 500)
Query Neighborhood Hits	1371	Target Neighborhood Hits	675	Shared Neighborhood Hits	516
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

PACN1_HUMAN
NC score	0.366788 (rank : 427)	θ value	0.000121331 (rank : 399)
Query Neighborhood Hits	1371	Target Neighborhood Hits	320	Shared Neighborhood Hits	287
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN3_HUMAN
NC score	0.366289 (rank : 428)	θ value	1.87187e-05 (rank : 334)
Query Neighborhood Hits	1371	Target Neighborhood Hits	385	Shared Neighborhood Hits	314
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

POF1B_MOUSE
NC score	0.365975 (rank : 429)	θ value	θ > 10 (rank : 2038)
Query Neighborhood Hits	1371	Target Neighborhood Hits	530	Shared Neighborhood Hits	396
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

T3JAM_MOUSE
NC score	0.365644 (rank : 430)	θ value	4.03905 (rank : 1225)
Query Neighborhood Hits	1371	Target Neighborhood Hits	535	Shared Neighborhood Hits	386
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

CDR2_MOUSE
NC score	0.365378 (rank : 431)	θ value	0.163984 (rank : 825)
Query Neighborhood Hits	1371	Target Neighborhood Hits	482	Shared Neighborhood Hits	373
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

NPHP1_MOUSE
NC score	0.365274 (rank : 432)	θ value	0.00509761 (rank : 584)
Query Neighborhood Hits	1371	Target Neighborhood Hits	267	Shared Neighborhood Hits	237
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

PACN3_MOUSE
NC score	0.364883 (rank : 433)	θ value	9.29e-05 (rank : 391)
Query Neighborhood Hits	1371	Target Neighborhood Hits	380	Shared Neighborhood Hits	325
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

RABE2_HUMAN
NC score	0.364836 (rank : 434)	θ value	θ > 10 (rank : 2056)
Query Neighborhood Hits	1371	Target Neighborhood Hits	545	Shared Neighborhood Hits	411
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

CT096_HUMAN
NC score	0.364520 (rank : 435)	θ value	0.365318 (rank : 902)
Query Neighborhood Hits	1371	Target Neighborhood Hits	438	Shared Neighborhood Hits	326
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

PININ_HUMAN
NC score	0.363690 (rank : 436)	θ value	0.0431538 (rank : 714)
Query Neighborhood Hits	1371	Target Neighborhood Hits	753	Shared Neighborhood Hits	446
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CRKL_MOUSE
NC score	0.363422 (rank : 437)	θ value	7.1131e-05 (rank : 380)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	218
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

KIF4A_MOUSE
NC score	0.363223 (rank : 438)	θ value	0.00020696 (rank : 420)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1033	Shared Neighborhood Hits	630
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

IF2P_HUMAN
NC score	0.362993 (rank : 439)	θ value	0.0736092 (rank : 757)
Query Neighborhood Hits	1371	Target Neighborhood Hits	889	Shared Neighborhood Hits	493
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CEP70_MOUSE
NC score	0.361739 (rank : 440)	θ value	1.06291 (rank : 1004)
Query Neighborhood Hits	1371	Target Neighborhood Hits	532	Shared Neighborhood Hits	408
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

K0552_HUMAN
NC score	0.360984 (rank : 441)	θ value	1.09739e-05 (rank : 301)
Query Neighborhood Hits	1371	Target Neighborhood Hits	442	Shared Neighborhood Hits	328
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

FGD6_HUMAN
NC score	0.360896 (rank : 442)	θ value	5.8054e-15 (rank : 46)
Query Neighborhood Hits	1371	Target Neighborhood Hits	237	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

WDR67_HUMAN
NC score	0.360540 (rank : 443)	θ value	7.59969e-07 (rank : 220)
Query Neighborhood Hits	1371	Target Neighborhood Hits	782	Shared Neighborhood Hits	460
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

TXLNG_MOUSE
NC score	0.360145 (rank : 444)	θ value	0.62314 (rank : 975)
Query Neighborhood Hits	1371	Target Neighborhood Hits	552	Shared Neighborhood Hits	415
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

TXLNG_HUMAN
NC score	0.360090 (rank : 445)	θ value	0.813845 (rank : 1001)
Query Neighborhood Hits	1371	Target Neighborhood Hits	568	Shared Neighborhood Hits	426
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

ASPP2_HUMAN
NC score	0.359692 (rank : 446)	θ value	0.00298849 (rank : 543)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1156	Shared Neighborhood Hits	569
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CF182_HUMAN
NC score	0.359651 (rank : 447)	θ value	0.000786445 (rank : 477)
Query Neighborhood Hits	1371	Target Neighborhood Hits	474	Shared Neighborhood Hits	369
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

MACF1_HUMAN
NC score	0.359379 (rank : 448)	θ value	0.0113563 (rank : 625)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1341	Shared Neighborhood Hits	664
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

CTGE6_HUMAN
NC score	0.359050 (rank : 449)	θ value	0.0431538 (rank : 709)
Query Neighborhood Hits	1371	Target Neighborhood Hits	650	Shared Neighborhood Hits	444
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

LIPB1_HUMAN
NC score	0.358878 (rank : 450)	θ value	0.0193708 (rank : 667)
Query Neighborhood Hits	1371	Target Neighborhood Hits	640	Shared Neighborhood Hits	450
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

ABI3_MOUSE
NC score	0.357846 (rank : 451)	θ value	7.1131e-05 (rank : 378)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

MYO5A_HUMAN
NC score	0.357364 (rank : 452)	θ value	0.813845 (rank : 986)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1092	Shared Neighborhood Hits	647
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

LZTS2_HUMAN
NC score	0.356389 (rank : 453)	θ value	0.00134147 (rank : 504)
Query Neighborhood Hits	1371	Target Neighborhood Hits	427	Shared Neighborhood Hits	321
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

ABI3_HUMAN
NC score	0.355855 (rank : 454)	θ value	4.1701e-05 (rank : 355)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	151
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

HAP1_HUMAN
NC score	0.355472 (rank : 455)	θ value	1.06291 (rank : 1014)
Query Neighborhood Hits	1371	Target Neighborhood Hits	606	Shared Neighborhood Hits	439
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

KIF5C_HUMAN
NC score	0.355420 (rank : 456)	θ value	0.00035302 (rank : 446)
Query Neighborhood Hits	1371	Target Neighborhood Hits	974	Shared Neighborhood Hits	618
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CRK_MOUSE
NC score	0.355410 (rank : 457)	θ value	0.000158464 (rank : 409)
Query Neighborhood Hits	1371	Target Neighborhood Hits	314	Shared Neighborhood Hits	221
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

ADIP_HUMAN
NC score	0.355169 (rank : 458)	θ value	0.0736092 (rank : 744)
Query Neighborhood Hits	1371	Target Neighborhood Hits	470	Shared Neighborhood Hits	379
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

MYO5A_MOUSE
NC score	0.354418 (rank : 459)	θ value	0.62314 (rank : 969)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1117	Shared Neighborhood Hits	661
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

AN30A_HUMAN
NC score	0.354371 (rank : 460)	θ value	0.00020696 (rank : 417)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1119	Shared Neighborhood Hits	556
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

PININ_MOUSE
NC score	0.353834 (rank : 461)	θ value	0.0431538 (rank : 715)
Query Neighborhood Hits	1371	Target Neighborhood Hits	777	Shared Neighborhood Hits	437
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

TXLNB_MOUSE
NC score	0.352834 (rank : 462)	θ value	θ > 10 (rank : 2303)
Query Neighborhood Hits	1371	Target Neighborhood Hits	640	Shared Neighborhood Hits	425
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

SNX23_HUMAN
NC score	0.351971 (rank : 463)	θ value	1.09739e-05 (rank : 305)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	593
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

MACF1_MOUSE
NC score	0.351821 (rank : 464)	θ value	0.00102713 (rank : 498)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1313	Shared Neighborhood Hits	658
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

CF152_MOUSE
NC score	0.351535 (rank : 465)	θ value	1.06291 (rank : 1005)
Query Neighborhood Hits	1371	Target Neighborhood Hits	597	Shared Neighborhood Hits	419
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

RASF8_HUMAN
NC score	0.351450 (rank : 466)	θ value	0.21417 (rank : 861)
Query Neighborhood Hits	1371	Target Neighborhood Hits	469	Shared Neighborhood Hits	364
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

CRK_HUMAN
NC score	0.351077 (rank : 467)	θ value	0.000158464 (rank : 408)
Query Neighborhood Hits	1371	Target Neighborhood Hits	308	Shared Neighborhood Hits	221
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

RAI14_HUMAN
NC score	0.350805 (rank : 468)	θ value	0.00102713 (rank : 499)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1367	Shared Neighborhood Hits	657
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

POF1B_HUMAN
NC score	0.350667 (rank : 469)	θ value	5.27518 (rank : 1257)
Query Neighborhood Hits	1371	Target Neighborhood Hits	494	Shared Neighborhood Hits	375
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

CEP70_HUMAN
NC score	0.350236 (rank : 470)	θ value	0.279714 (rank : 877)
Query Neighborhood Hits	1371	Target Neighborhood Hits	432	Shared Neighborhood Hits	359
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CCD42_HUMAN
NC score	0.349514 (rank : 471)	θ value	0.0193708 (rank : 658)
Query Neighborhood Hits	1371	Target Neighborhood Hits	406	Shared Neighborhood Hits	346
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

NPHP1_HUMAN
NC score	0.347897 (rank : 472)	θ value	9.92553e-07 (rank : 226)
Query Neighborhood Hits	1371	Target Neighborhood Hits	288	Shared Neighborhood Hits	235
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

PACN1_MOUSE
NC score	0.347694 (rank : 473)	θ value	0.000270298 (rank : 431)
Query Neighborhood Hits	1371	Target Neighborhood Hits	283	Shared Neighborhood Hits	247
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

CTGE2_HUMAN
NC score	0.347079 (rank : 474)	θ value	θ > 10 (rank : 1556)
Query Neighborhood Hits	1371	Target Neighborhood Hits	594	Shared Neighborhood Hits	421
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

MOES_MOUSE
NC score	0.346814 (rank : 475)	θ value	0.00298849 (rank : 552)
Query Neighborhood Hits	1371	Target Neighborhood Hits	923	Shared Neighborhood Hits	600
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MAP1A_HUMAN
NC score	0.345963 (rank : 476)	θ value	0.163984 (rank : 832)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1626	Shared Neighborhood Hits	600
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NEB2_MOUSE
NC score	0.345398 (rank : 477)	θ value	0.0252991 (rank : 683)
Query Neighborhood Hits	1371	Target Neighborhood Hits	889	Shared Neighborhood Hits	535
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

UTRO_HUMAN
NC score	0.342237 (rank : 478)	θ value	0.0193708 (rank : 672)
Query Neighborhood Hits	1371	Target Neighborhood Hits	960	Shared Neighborhood Hits	563
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

DBNL_HUMAN
NC score	0.341948 (rank : 479)	θ value	0.000270298 (rank : 427)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

CAR10_HUMAN
NC score	0.341412 (rank : 480)	θ value	0.0431538 (rank : 705)
Query Neighborhood Hits	1371	Target Neighborhood Hits	569	Shared Neighborhood Hits	416
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CCD45_HUMAN
NC score	0.340914 (rank : 481)	θ value	0.00665767 (rank : 590)
Query Neighborhood Hits	1371	Target Neighborhood Hits	525	Shared Neighborhood Hits	364
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

SKIL_MOUSE
NC score	0.340813 (rank : 482)	θ value	0.0563607 (rank : 736)
Query Neighborhood Hits	1371	Target Neighborhood Hits	719	Shared Neighborhood Hits	506
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

MOES_HUMAN
NC score	0.340450 (rank : 483)	θ value	0.0148317 (rank : 646)
Query Neighborhood Hits	1371	Target Neighborhood Hits	892	Shared Neighborhood Hits	595
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

DBNL_MOUSE
NC score	0.339517 (rank : 484)	θ value	0.000270298 (rank : 428)
Query Neighborhood Hits	1371	Target Neighborhood Hits	306	Shared Neighborhood Hits	227
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

TACC2_HUMAN
NC score	0.339367 (rank : 485)	θ value	θ > 10 (rank : 2241)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	477
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

OSTF1_HUMAN
NC score	0.338066 (rank : 486)	θ value	5.81887e-07 (rank : 212)
Query Neighborhood Hits	1371	Target Neighborhood Hits	466	Shared Neighborhood Hits	229
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

CCD45_MOUSE
NC score	0.337858 (rank : 487)	θ value	0.00228821 (rank : 529)
Query Neighborhood Hits	1371	Target Neighborhood Hits	663	Shared Neighborhood Hits	395
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

HOME1_MOUSE
NC score	0.337382 (rank : 488)	θ value	0.00509761 (rank : 583)
Query Neighborhood Hits	1371	Target Neighborhood Hits	630	Shared Neighborhood Hits	435
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

ENAH_HUMAN
NC score	0.337127 (rank : 489)	θ value	0.0193708 (rank : 661)
Query Neighborhood Hits	1371	Target Neighborhood Hits	784	Shared Neighborhood Hits	456
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

NDE1_MOUSE
NC score	0.336844 (rank : 490)	θ value	θ > 10 (rank : 1963)
Query Neighborhood Hits	1371	Target Neighborhood Hits	602	Shared Neighborhood Hits	450
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

KIF5A_HUMAN
NC score	0.335930 (rank : 491)	θ value	0.00175202 (rank : 516)
Query Neighborhood Hits	1371	Target Neighborhood Hits	843	Shared Neighborhood Hits	560
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

NEB2_HUMAN
NC score	0.335820 (rank : 492)	θ value	0.0252991 (rank : 682)
Query Neighborhood Hits	1371	Target Neighborhood Hits	883	Shared Neighborhood Hits	524
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

TRAK2_HUMAN
NC score	0.335746 (rank : 493)	θ value	5.27518 (rank : 1269)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	358
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

ASPP1_HUMAN
NC score	0.334298 (rank : 494)	θ value	0.00390308 (rank : 563)
Query Neighborhood Hits	1371	Target Neighborhood Hits	956	Shared Neighborhood Hits	485
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TXLNB_HUMAN
NC score	0.333375 (rank : 495)	θ value	θ > 10 (rank : 2302)
Query Neighborhood Hits	1371	Target Neighborhood Hits	912	Shared Neighborhood Hits	469
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

MFAP1_MOUSE
NC score	0.333105 (rank : 496)	θ value	0.00665767 (rank : 596)
Query Neighborhood Hits	1371	Target Neighborhood Hits	353	Shared Neighborhood Hits	271
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

KIF5A_MOUSE
NC score	0.333020 (rank : 497)	θ value	0.00134147 (rank : 503)
Query Neighborhood Hits	1371	Target Neighborhood Hits	859	Shared Neighborhood Hits	564
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

CU013_HUMAN
NC score	0.332597 (rank : 498)	θ value	3.0926 (rank : 1170)
Query Neighborhood Hits	1371	Target Neighborhood Hits	405	Shared Neighborhood Hits	314
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

ASPP1_MOUSE
NC score	0.332510 (rank : 499)	θ value	0.00102713 (rank : 493)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1244	Shared Neighborhood Hits	521
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

KI21A_HUMAN
NC score	0.332125 (rank : 500)	θ value	1.87187e-05 (rank : 329)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1543	Shared Neighborhood Hits	719
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

LZTS2_MOUSE
NC score	0.332013 (rank : 501)	θ value	0.00228821 (rank : 535)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	295
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

GNRP_MOUSE
NC score	0.331152 (rank : 502)	θ value	7.09661e-13 (rank : 70)
Query Neighborhood Hits	1371	Target Neighborhood Hits	191	Shared Neighborhood Hits	92
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

TACC3_MOUSE
NC score	0.329197 (rank : 503)	θ value	0.813845 (rank : 998)
Query Neighborhood Hits	1371	Target Neighborhood Hits	607	Shared Neighborhood Hits	426
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

OSTF1_MOUSE
NC score	0.327806 (rank : 504)	θ value	1.29631e-06 (rank : 233)
Query Neighborhood Hits	1371	Target Neighborhood Hits	467	Shared Neighborhood Hits	228
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

HOME2_HUMAN
NC score	0.327119 (rank : 505)	θ value	θ > 10 (rank : 1723)
Query Neighborhood Hits	1371	Target Neighborhood Hits	532	Shared Neighborhood Hits	399
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

TACC1_MOUSE
NC score	0.326820 (rank : 506)	θ value	0.365318 (rank : 927)
Query Neighborhood Hits	1371	Target Neighborhood Hits	667	Shared Neighborhood Hits	428
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

AMOL2_HUMAN
NC score	0.326505 (rank : 507)	θ value	4.03905 (rank : 1195)
Query Neighborhood Hits	1371	Target Neighborhood Hits	603	Shared Neighborhood Hits	419
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

PLCB4_HUMAN
NC score	0.326470 (rank : 508)	θ value	0.000602161 (rank : 469)
Query Neighborhood Hits	1371	Target Neighborhood Hits	658	Shared Neighborhood Hits	464
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

RASF8_MOUSE
NC score	0.326091 (rank : 509)	θ value	0.0736092 (rank : 763)
Query Neighborhood Hits	1371	Target Neighborhood Hits	391	Shared Neighborhood Hits	319
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

AMOL2_MOUSE
NC score	0.325207 (rank : 510)	θ value	θ > 10 (rank : 1400)
Query Neighborhood Hits	1371	Target Neighborhood Hits	591	Shared Neighborhood Hits	410
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

HOME1_HUMAN
NC score	0.324256 (rank : 511)	θ value	0.00869519 (rank : 607)
Query Neighborhood Hits	1371	Target Neighborhood Hits	564	Shared Neighborhood Hits	411
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

TCRG1_HUMAN
NC score	0.323625 (rank : 512)	θ value	2.44474e-05 (rank : 346)
Query Neighborhood Hits	1371	Target Neighborhood Hits	929	Shared Neighborhood Hits	447
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TACC1_HUMAN
NC score	0.321593 (rank : 513)	θ value	θ > 10 (rank : 2240)
Query Neighborhood Hits	1371	Target Neighborhood Hits	597	Shared Neighborhood Hits	424
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

STIM1_HUMAN
NC score	0.321566 (rank : 514)	θ value	0.0736092 (rank : 767)
Query Neighborhood Hits	1371	Target Neighborhood Hits	665	Shared Neighborhood Hits	455
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

LMNB1_HUMAN
NC score	0.321458 (rank : 515)	θ value	0.62314 (rank : 967)
Query Neighborhood Hits	1371	Target Neighborhood Hits	714	Shared Neighborhood Hits	506
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

INVO_MOUSE
NC score	0.321299 (rank : 516)	θ value	0.279714 (rank : 882)
Query Neighborhood Hits	1371	Target Neighborhood Hits	474	Shared Neighborhood Hits	284
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

TCRG1_MOUSE
NC score	0.321295 (rank : 517)	θ value	2.44474e-05 (rank : 347)
Query Neighborhood Hits	1371	Target Neighborhood Hits	947	Shared Neighborhood Hits	445
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

GNRP_HUMAN
NC score	0.321015 (rank : 518)	θ value	4.16044e-13 (rank : 66)
Query Neighborhood Hits	1371	Target Neighborhood Hits	239	Shared Neighborhood Hits	121
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

LMNB2_HUMAN
NC score	0.321007 (rank : 519)	θ value	0.000121331 (rank : 396)
Query Neighborhood Hits	1371	Target Neighborhood Hits	723	Shared Neighborhood Hits	507
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

LIPB2_MOUSE
NC score	0.320159 (rank : 520)	θ value	0.0961366 (rank : 787)
Query Neighborhood Hits	1371	Target Neighborhood Hits	570	Shared Neighborhood Hits	395
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

LASP1_HUMAN
NC score	0.320146 (rank : 521)	θ value	4.1701e-05 (rank : 361)
Query Neighborhood Hits	1371	Target Neighborhood Hits	293	Shared Neighborhood Hits	172
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LMNB1_MOUSE
NC score	0.319143 (rank : 522)	θ value	0.279714 (rank : 883)
Query Neighborhood Hits	1371	Target Neighborhood Hits	719	Shared Neighborhood Hits	499
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

STIM1_MOUSE
NC score	0.318391 (rank : 523)	θ value	0.163984 (rank : 833)
Query Neighborhood Hits	1371	Target Neighborhood Hits	660	Shared Neighborhood Hits	457
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

CDR2_HUMAN
NC score	0.318170 (rank : 524)	θ value	2.36792 (rank : 1126)
Query Neighborhood Hits	1371	Target Neighborhood Hits	404	Shared Neighborhood Hits	316
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

LASP1_MOUSE
NC score	0.318124 (rank : 525)	θ value	4.1701e-05 (rank : 362)
Query Neighborhood Hits	1371	Target Neighborhood Hits	297	Shared Neighborhood Hits	172
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ANR18_HUMAN
NC score	0.317864 (rank : 526)	θ value	0.0330416 (rank : 694)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1106	Shared Neighborhood Hits	571
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CAR14_MOUSE
NC score	0.317820 (rank : 527)	θ value	0.279714 (rank : 875)
Query Neighborhood Hits	1371	Target Neighborhood Hits	526	Shared Neighborhood Hits	397
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

PLCG1_MOUSE
NC score	0.317583 (rank : 528)	θ value	8.11959e-09 (rank : 133)
Query Neighborhood Hits	1371	Target Neighborhood Hits	314	Shared Neighborhood Hits	206
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

MYO5B_HUMAN
NC score	0.317552 (rank : 529)	θ value	0.000786445 (rank : 489)
Query Neighborhood Hits	1371	Target Neighborhood Hits	911	Shared Neighborhood Hits	582
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

LIPA3_MOUSE
NC score	0.317272 (rank : 530)	θ value	1.81305 (rank : 1098)
Query Neighborhood Hits	1371	Target Neighborhood Hits	636	Shared Neighborhood Hits	437
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPB2_HUMAN
NC score	0.317088 (rank : 531)	θ value	0.813845 (rank : 983)
Query Neighborhood Hits	1371	Target Neighborhood Hits	599	Shared Neighborhood Hits	422
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

CEP35_HUMAN
NC score	0.316658 (rank : 532)	θ value	0.0736092 (rank : 748)
Query Neighborhood Hits	1371	Target Neighborhood Hits	811	Shared Neighborhood Hits	443
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CENPH_HUMAN
NC score	0.316204 (rank : 533)	θ value	1.81305 (rank : 1081)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

RENT2_HUMAN
NC score	0.315846 (rank : 534)	θ value	0.813845 (rank : 992)
Query Neighborhood Hits	1371	Target Neighborhood Hits	618	Shared Neighborhood Hits	396
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

VDP_MOUSE
NC score	0.313698 (rank : 535)	θ value	θ > 10 (rank : 2322)
Query Neighborhood Hits	1371	Target Neighborhood Hits	469	Shared Neighborhood Hits	340
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

AL2SB_HUMAN
NC score	0.313551 (rank : 536)	θ value	4.03905 (rank : 1194)
Query Neighborhood Hits	1371	Target Neighborhood Hits	294	Shared Neighborhood Hits	241
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

NEB1_HUMAN
NC score	0.312978 (rank : 537)	θ value	0.000270298 (rank : 430)
Query Neighborhood Hits	1371	Target Neighborhood Hits	829	Shared Neighborhood Hits	450
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

CTRO_MOUSE
NC score	0.312768 (rank : 538)	θ value	1.43324e-05 (rank : 311)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2344	Shared Neighborhood Hits	850
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

PHLB1_HUMAN
NC score	0.311165 (rank : 539)	θ value	0.21417 (rank : 859)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1038	Shared Neighborhood Hits	484
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

REN3B_HUMAN
NC score	0.311048 (rank : 540)	θ value	3.0926 (rank : 1183)
Query Neighborhood Hits	1371	Target Neighborhood Hits	412	Shared Neighborhood Hits	301
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

IMMT_HUMAN
NC score	0.310395 (rank : 541)	θ value	5.27518 (rank : 1248)
Query Neighborhood Hits	1371	Target Neighborhood Hits	494	Shared Neighborhood Hits	362
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

LMNA_MOUSE
NC score	0.309382 (rank : 542)	θ value	2.36792 (rank : 1145)
Query Neighborhood Hits	1371	Target Neighborhood Hits	661	Shared Neighborhood Hits	490
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

AHI1_HUMAN
NC score	0.309279 (rank : 543)	θ value	3.08544e-08 (rank : 155)
Query Neighborhood Hits	1371	Target Neighborhood Hits	537	Shared Neighborhood Hits	242
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CIP4_HUMAN
NC score	0.309127 (rank : 544)	θ value	0.163984 (rank : 826)
Query Neighborhood Hits	1371	Target Neighborhood Hits	374	Shared Neighborhood Hits	304
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CDC37_HUMAN
NC score	0.307796 (rank : 545)	θ value	0.00665767 (rank : 593)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	357
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

PLCG1_HUMAN
NC score	0.307525 (rank : 546)	θ value	5.26297e-08 (rank : 168)
Query Neighborhood Hits	1371	Target Neighborhood Hits	293	Shared Neighborhood Hits	197
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

MMRN1_HUMAN
NC score	0.306224 (rank : 547)	θ value	0.365318 (rank : 914)
Query Neighborhood Hits	1371	Target Neighborhood Hits	636	Shared Neighborhood Hits	313
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

ZC313_HUMAN
NC score	0.305811 (rank : 548)	θ value	1.38821 (rank : 1076)
Query Neighborhood Hits	1371	Target Neighborhood Hits	772	Shared Neighborhood Hits	368
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

LMNA_HUMAN
NC score	0.305296 (rank : 549)	θ value	2.36792 (rank : 1144)
Query Neighborhood Hits	1371	Target Neighborhood Hits	653	Shared Neighborhood Hits	489
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

NOXO1_MOUSE
NC score	0.304600 (rank : 550)	θ value	1.29631e-06 (rank : 232)
Query Neighborhood Hits	1371	Target Neighborhood Hits	114	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

CCD93_MOUSE
NC score	0.304562 (rank : 551)	θ value	0.279714 (rank : 876)
Query Neighborhood Hits	1371	Target Neighborhood Hits	362	Shared Neighborhood Hits	288
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

NFM_MOUSE
NC score	0.304343 (rank : 552)	θ value	0.00390308 (rank : 570)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1159	Shared Neighborhood Hits	634
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

TACC2_MOUSE
NC score	0.303456 (rank : 553)	θ value	θ > 10 (rank : 2242)
Query Neighborhood Hits	1371	Target Neighborhood Hits	774	Shared Neighborhood Hits	427
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

LRSM1_HUMAN
NC score	0.303254 (rank : 554)	θ value	0.0113563 (rank : 624)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1078	Shared Neighborhood Hits	521
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

ADIP_MOUSE
NC score	0.302887 (rank : 555)	θ value	3.0926 (rank : 1163)
Query Neighborhood Hits	1371	Target Neighborhood Hits	415	Shared Neighborhood Hits	337
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

RADI_MOUSE
NC score	0.302481 (rank : 556)	θ value	0.00509761 (rank : 585)
Query Neighborhood Hits	1371	Target Neighborhood Hits	773	Shared Neighborhood Hits	530
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

PHLB3_HUMAN
NC score	0.302321 (rank : 557)	θ value	θ > 10 (rank : 2020)
Query Neighborhood Hits	1371	Target Neighborhood Hits	304	Shared Neighborhood Hits	252
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

MORC3_HUMAN
NC score	0.302115 (rank : 558)	θ value	0.0330416 (rank : 698)
Query Neighborhood Hits	1371	Target Neighborhood Hits	489	Shared Neighborhood Hits	369
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

PLVAP_HUMAN
NC score	0.301727 (rank : 559)	θ value	0.125558 (rank : 814)
Query Neighborhood Hits	1371	Target Neighborhood Hits	397	Shared Neighborhood Hits	313
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

GLE1_MOUSE
NC score	0.301354 (rank : 560)	θ value	0.0736092 (rank : 756)
Query Neighborhood Hits	1371	Target Neighborhood Hits	504	Shared Neighborhood Hits	370
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

ROCK1_MOUSE
NC score	0.301142 (rank : 561)	θ value	2.36244e-08 (rank : 153)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2126	Shared Neighborhood Hits	799
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

RADI_HUMAN
NC score	0.301077 (rank : 562)	θ value	0.00228821 (rank : 537)
Query Neighborhood Hits	1371	Target Neighborhood Hits	741	Shared Neighborhood Hits	519
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

PLCG2_HUMAN
NC score	0.300752 (rank : 563)	θ value	3.77169e-06 (rank : 269)
Query Neighborhood Hits	1371	Target Neighborhood Hits	280	Shared Neighborhood Hits	189
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

AHI1_MOUSE
NC score	0.299756 (rank : 564)	θ value	5.26297e-08 (rank : 164)
Query Neighborhood Hits	1371	Target Neighborhood Hits	496	Shared Neighborhood Hits	220
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

NFM_HUMAN
NC score	0.299227 (rank : 565)	θ value	0.0148317 (rank : 647)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1328	Shared Neighborhood Hits	638
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SPTB2_MOUSE
NC score	0.298801 (rank : 566)	θ value	0.00509761 (rank : 586)
Query Neighborhood Hits	1371	Target Neighborhood Hits	770	Shared Neighborhood Hits	477
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

AMOT_HUMAN
NC score	0.298422 (rank : 567)	θ value	1.81305 (rank : 1077)
Query Neighborhood Hits	1371	Target Neighborhood Hits	712	Shared Neighborhood Hits	391
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

NEBU_HUMAN
NC score	0.298352 (rank : 568)	θ value	2.44474e-05 (rank : 344)
Query Neighborhood Hits	1371	Target Neighborhood Hits	420	Shared Neighborhood Hits	290
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

KI21A_MOUSE
NC score	0.298165 (rank : 569)	θ value	0.00102713 (rank : 496)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1317	Shared Neighborhood Hits	647
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MAP9_HUMAN
NC score	0.297986 (rank : 570)	θ value	0.365318 (rank : 913)
Query Neighborhood Hits	1371	Target Neighborhood Hits	518	Shared Neighborhood Hits	338
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

FARP2_MOUSE
NC score	0.297919 (rank : 571)	θ value	4.59992e-12 (rank : 84)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	95
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

LMNB2_MOUSE
NC score	0.297577 (rank : 572)	θ value	5.27518 (rank : 1252)
Query Neighborhood Hits	1371	Target Neighborhood Hits	674	Shared Neighborhood Hits	468
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

STXB4_HUMAN
NC score	0.297553 (rank : 573)	θ value	0.365318 (rank : 926)
Query Neighborhood Hits	1371	Target Neighborhood Hits	616	Shared Neighborhood Hits	394
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TACC3_HUMAN
NC score	0.297330 (rank : 574)	θ value	θ > 10 (rank : 2243)
Query Neighborhood Hits	1371	Target Neighborhood Hits	779	Shared Neighborhood Hits	421
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

MRCKB_HUMAN
NC score	0.296543 (rank : 575)	θ value	2.79066e-09 (rank : 129)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2239	Shared Neighborhood Hits	815
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SPTB2_HUMAN
NC score	0.295458 (rank : 576)	θ value	0.0431538 (rank : 717)
Query Neighborhood Hits	1371	Target Neighborhood Hits	748	Shared Neighborhood Hits	467
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

RPGR1_MOUSE
NC score	0.294433 (rank : 577)	θ value	1.38821 (rank : 1066)
Query Neighborhood Hits	1371	Target Neighborhood Hits	713	Shared Neighborhood Hits	418
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RBBP8_HUMAN
NC score	0.293973 (rank : 578)	θ value	0.0113563 (rank : 632)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	323
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

CLC4F_HUMAN
NC score	0.292529 (rank : 579)	θ value	θ > 10 (rank : 1529)
Query Neighborhood Hits	1371	Target Neighborhood Hits	513	Shared Neighborhood Hits	317
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

TNNT2_HUMAN
NC score	0.292528 (rank : 580)	θ value	0.21417 (rank : 867)
Query Neighborhood Hits	1371	Target Neighborhood Hits	433	Shared Neighborhood Hits	310
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

CAR14_HUMAN
NC score	0.291980 (rank : 581)	θ value	θ > 10 (rank : 1470)
Query Neighborhood Hits	1371	Target Neighborhood Hits	449	Shared Neighborhood Hits	345
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

MRCKB_MOUSE
NC score	0.291484 (rank : 582)	θ value	6.21693e-09 (rank : 132)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2180	Shared Neighborhood Hits	799
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MFAP1_HUMAN
NC score	0.290777 (rank : 583)	θ value	0.00869519 (rank : 611)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	242
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MRIP_MOUSE
NC score	0.289303 (rank : 584)	θ value	θ > 10 (rank : 1926)
Query Neighborhood Hits	1371	Target Neighborhood Hits	569	Shared Neighborhood Hits	366
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

TEKT1_MOUSE
NC score	0.289101 (rank : 585)	θ value	0.125558 (rank : 816)
Query Neighborhood Hits	1371	Target Neighborhood Hits	399	Shared Neighborhood Hits	303
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

REPS2_HUMAN
NC score	0.288696 (rank : 586)	θ value	4.91457e-14 (rank : 55)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

ROCK2_MOUSE
NC score	0.288180 (rank : 587)	θ value	1.29631e-06 (rank : 236)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2072	Shared Neighborhood Hits	782
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

MRIP_HUMAN
NC score	0.287473 (rank : 588)	θ value	θ > 10 (rank : 1925)
Query Neighborhood Hits	1371	Target Neighborhood Hits	578	Shared Neighborhood Hits	362
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

EZRI_MOUSE
NC score	0.286377 (rank : 589)	θ value	0.0736092 (rank : 755)
Query Neighborhood Hits	1371	Target Neighborhood Hits	693	Shared Neighborhood Hits	508
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

CT032_HUMAN
NC score	0.286328 (rank : 590)	θ value	0.00390308 (rank : 564)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CTRO_HUMAN
NC score	0.286021 (rank : 591)	θ value	0.00390308 (rank : 565)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2092	Shared Neighborhood Hits	781
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ROCK1_HUMAN
NC score	0.285981 (rank : 592)	θ value	1.80886e-08 (rank : 147)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2000	Shared Neighborhood Hits	748
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

OLR1_MOUSE
NC score	0.285749 (rank : 593)	θ value	θ > 10 (rank : 1995)
Query Neighborhood Hits	1371	Target Neighborhood Hits	596	Shared Neighborhood Hits	374
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

TTC3_HUMAN
NC score	0.285502 (rank : 594)	θ value	8.99809 (rank : 1365)
Query Neighborhood Hits	1371	Target Neighborhood Hits	664	Shared Neighborhood Hits	370
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

NDEL1_HUMAN
NC score	0.284525 (rank : 595)	θ value	θ > 10 (rank : 1964)
Query Neighborhood Hits	1371	Target Neighborhood Hits	415	Shared Neighborhood Hits	335
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

REPS2_MOUSE
NC score	0.284351 (rank : 596)	θ value	3.52202e-12 (rank : 82)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

COVA1_HUMAN
NC score	0.283836 (rank : 597)	θ value	4.03905 (rank : 1200)
Query Neighborhood Hits	1371	Target Neighborhood Hits	416	Shared Neighborhood Hits	298
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

BRAP_HUMAN
NC score	0.283660 (rank : 598)	θ value	0.47712 (rank : 930)
Query Neighborhood Hits	1371	Target Neighborhood Hits	560	Shared Neighborhood Hits	353
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

NDEL1_MOUSE
NC score	0.283532 (rank : 599)	θ value	θ > 10 (rank : 1965)
Query Neighborhood Hits	1371	Target Neighborhood Hits	420	Shared Neighborhood Hits	337
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

GP73_MOUSE
NC score	0.283034 (rank : 600)	θ value	θ > 10 (rank : 1703)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	326
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

SKIL_HUMAN
NC score	0.282963 (rank : 601)	θ value	θ > 10 (rank : 2154)
Query Neighborhood Hits	1371	Target Neighborhood Hits	460	Shared Neighborhood Hits	355
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

MAP9_MOUSE
NC score	0.282955 (rank : 602)	θ value	3.0926 (rank : 1181)
Query Neighborhood Hits	1371	Target Neighborhood Hits	529	Shared Neighborhood Hits	325
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

GLE1_HUMAN
NC score	0.282499 (rank : 603)	θ value	0.0431538 (rank : 712)
Query Neighborhood Hits	1371	Target Neighborhood Hits	445	Shared Neighborhood Hits	321
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

U2AFM_HUMAN
NC score	0.281628 (rank : 604)	θ value	0.47712 (rank : 956)
Query Neighborhood Hits	1371	Target Neighborhood Hits	577	Shared Neighborhood Hits	417
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

BFSP1_HUMAN
NC score	0.280827 (rank : 605)	θ value	0.163984 (rank : 822)
Query Neighborhood Hits	1371	Target Neighborhood Hits	508	Shared Neighborhood Hits	386
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

MYO6_HUMAN
NC score	0.280754 (rank : 606)	θ value	0.00035302 (rank : 448)
Query Neighborhood Hits	1371	Target Neighborhood Hits	727	Shared Neighborhood Hits	518
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

ROCK2_HUMAN
NC score	0.280698 (rank : 607)	θ value	4.45536e-07 (rank : 204)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2073	Shared Neighborhood Hits	761
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ZWINT_HUMAN
NC score	0.280012 (rank : 608)	θ value	0.125558 (rank : 818)
Query Neighborhood Hits	1371	Target Neighborhood Hits	333	Shared Neighborhood Hits	265
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

TNNT2_MOUSE
NC score	0.279636 (rank : 609)	θ value	0.0961366 (rank : 799)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	288
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

FARP2_HUMAN
NC score	0.279506 (rank : 610)	θ value	1.33837e-11 (rank : 92)
Query Neighborhood Hits	1371	Target Neighborhood Hits	240	Shared Neighborhood Hits	88
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

JIP3_MOUSE
NC score	0.279230 (rank : 611)	θ value	0.125558 (rank : 810)
Query Neighborhood Hits	1371	Target Neighborhood Hits	759	Shared Neighborhood Hits	492
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

PRC1_MOUSE
NC score	0.279066 (rank : 612)	θ value	0.21417 (rank : 860)
Query Neighborhood Hits	1371	Target Neighborhood Hits	382	Shared Neighborhood Hits	303
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

P85B_HUMAN
NC score	0.278912 (rank : 613)	θ value	0.21417 (rank : 858)
Query Neighborhood Hits	1371	Target Neighborhood Hits	543	Shared Neighborhood Hits	357
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

BCR_HUMAN
NC score	0.278608 (rank : 614)	θ value	3.29651e-10 (rank : 113)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	99
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

EZRI_HUMAN
NC score	0.278434 (rank : 615)	θ value	0.47712 (rank : 938)
Query Neighborhood Hits	1371	Target Neighborhood Hits	663	Shared Neighborhood Hits	491
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

CCD42_MOUSE
NC score	0.278210 (rank : 616)	θ value	0.0736092 (rank : 747)
Query Neighborhood Hits	1371	Target Neighborhood Hits	284	Shared Neighborhood Hits	244
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

MYO1F_HUMAN
NC score	0.277249 (rank : 617)	θ value	4.45536e-07 (rank : 200)
Query Neighborhood Hits	1371	Target Neighborhood Hits	275	Shared Neighborhood Hits	231
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

3BP5_HUMAN
NC score	0.276645 (rank : 618)	θ value	θ > 10 (rank : 1373)
Query Neighborhood Hits	1371	Target Neighborhood Hits	375	Shared Neighborhood Hits	296
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

MYO1F_MOUSE
NC score	0.276610 (rank : 619)	θ value	4.45536e-07 (rank : 201)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	229
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

KIFC3_HUMAN
NC score	0.276138 (rank : 620)	θ value	0.365318 (rank : 910)
Query Neighborhood Hits	1371	Target Neighborhood Hits	619	Shared Neighborhood Hits	456
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

MYO10_HUMAN
NC score	0.276059 (rank : 621)	θ value	0.0330416 (rank : 699)
Query Neighborhood Hits	1371	Target Neighborhood Hits	920	Shared Neighborhood Hits	557
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

U2AFM_MOUSE
NC score	0.275680 (rank : 622)	θ value	4.03905 (rank : 1229)
Query Neighborhood Hits	1371	Target Neighborhood Hits	543	Shared Neighborhood Hits	404
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

MYO1E_HUMAN
NC score	0.275337 (rank : 623)	θ value	4.45536e-07 (rank : 199)
Query Neighborhood Hits	1371	Target Neighborhood Hits	293	Shared Neighborhood Hits	234
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

REPS1_MOUSE
NC score	0.275285 (rank : 624)	θ value	2.98157e-11 (rank : 98)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	70
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

FARP1_HUMAN
NC score	0.274873 (rank : 625)	θ value	8.38298e-14 (rank : 58)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

REPS1_HUMAN
NC score	0.274192 (rank : 626)	θ value	2.98157e-11 (rank : 97)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	69
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

JIP3_HUMAN
NC score	0.273736 (rank : 627)	θ value	0.0193708 (rank : 665)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1039	Shared Neighborhood Hits	507
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

KIF23_HUMAN
NC score	0.273634 (rank : 628)	θ value	0.00665767 (rank : 595)
Query Neighborhood Hits	1371	Target Neighborhood Hits	618	Shared Neighborhood Hits	451
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

FNBP2_HUMAN
NC score	0.273312 (rank : 629)	θ value	3.77169e-06 (rank : 266)
Query Neighborhood Hits	1371	Target Neighborhood Hits	432	Shared Neighborhood Hits	293
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

BCAR1_MOUSE
NC score	0.273268 (rank : 630)	θ value	7.1131e-05 (rank : 379)
Query Neighborhood Hits	1371	Target Neighborhood Hits	438	Shared Neighborhood Hits	191
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

LRRF1_HUMAN
NC score	0.272643 (rank : 631)	θ value	0.47712 (rank : 943)
Query Neighborhood Hits	1371	Target Neighborhood Hits	625	Shared Neighborhood Hits	375
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

STMN1_HUMAN
NC score	0.272078 (rank : 632)	θ value	0.00869519 (rank : 615)
Query Neighborhood Hits	1371	Target Neighborhood Hits	554	Shared Neighborhood Hits	358
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

MRCKA_HUMAN
NC score	0.272045 (rank : 633)	θ value	9.92553e-07 (rank : 224)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1999	Shared Neighborhood Hits	774
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

SAFB2_HUMAN
NC score	0.271752 (rank : 634)	θ value	2.36792 (rank : 1155)
Query Neighborhood Hits	1371	Target Neighborhood Hits	720	Shared Neighborhood Hits	389
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

APOA4_MOUSE
NC score	0.271534 (rank : 635)	θ value	θ > 10 (rank : 1418)
Query Neighborhood Hits	1371	Target Neighborhood Hits	435	Shared Neighborhood Hits	297
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

P85B_MOUSE
NC score	0.270539 (rank : 636)	θ value	0.279714 (rank : 886)
Query Neighborhood Hits	1371	Target Neighborhood Hits	519	Shared Neighborhood Hits	360
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CAR10_MOUSE
NC score	0.269804 (rank : 637)	θ value	6.88961 (rank : 1287)
Query Neighborhood Hits	1371	Target Neighborhood Hits	407	Shared Neighborhood Hits	323
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

STXB4_MOUSE
NC score	0.268972 (rank : 638)	θ value	θ > 10 (rank : 2217)
Query Neighborhood Hits	1371	Target Neighborhood Hits	629	Shared Neighborhood Hits	394
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TARA_MOUSE
NC score	0.268595 (rank : 639)	θ value	0.0563607 (rank : 739)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1133	Shared Neighborhood Hits	429
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

APOA4_HUMAN
NC score	0.268261 (rank : 640)	θ value	θ > 10 (rank : 1417)
Query Neighborhood Hits	1371	Target Neighborhood Hits	399	Shared Neighborhood Hits	285
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

KIFC3_MOUSE
NC score	0.268037 (rank : 641)	θ value	0.365318 (rank : 911)
Query Neighborhood Hits	1371	Target Neighborhood Hits	571	Shared Neighborhood Hits	420
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

EFS_MOUSE
NC score	0.267324 (rank : 642)	θ value	0.0193708 (rank : 660)
Query Neighborhood Hits	1371	Target Neighborhood Hits	389	Shared Neighborhood Hits	186
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

3BP5_MOUSE
NC score	0.267092 (rank : 643)	θ value	θ > 10 (rank : 1374)
Query Neighborhood Hits	1371	Target Neighborhood Hits	346	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

STMN1_MOUSE
NC score	0.266980 (rank : 644)	θ value	0.00869519 (rank : 616)
Query Neighborhood Hits	1371	Target Neighborhood Hits	560	Shared Neighborhood Hits	358
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

NTBP1_MOUSE
NC score	0.266623 (rank : 645)	θ value	0.365318 (rank : 918)
Query Neighborhood Hits	1371	Target Neighborhood Hits	528	Shared Neighborhood Hits	296
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

BCAR1_HUMAN
NC score	0.266563 (rank : 646)	θ value	0.00035302 (rank : 437)
Query Neighborhood Hits	1371	Target Neighborhood Hits	554	Shared Neighborhood Hits	199
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PLCB2_HUMAN
NC score	0.264375 (rank : 647)	θ value	0.00175202 (rank : 522)
Query Neighborhood Hits	1371	Target Neighborhood Hits	608	Shared Neighborhood Hits	422
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

SRGP1_HUMAN
NC score	0.264237 (rank : 648)	θ value	1.29631e-06 (rank : 238)
Query Neighborhood Hits	1371	Target Neighborhood Hits	390	Shared Neighborhood Hits	275
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

VIME_MOUSE
NC score	0.263846 (rank : 649)	θ value	0.000786445 (rank : 492)
Query Neighborhood Hits	1371	Target Neighborhood Hits	716	Shared Neighborhood Hits	513
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

RHG04_HUMAN
NC score	0.263773 (rank : 650)	θ value	9.92553e-07 (rank : 228)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	217
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

KIF3A_MOUSE
NC score	0.263717 (rank : 651)	θ value	0.125558 (rank : 812)
Query Neighborhood Hits	1371	Target Neighborhood Hits	715	Shared Neighborhood Hits	511
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF11_HUMAN
NC score	0.263101 (rank : 652)	θ value	θ > 10 (rank : 1810)
Query Neighborhood Hits	1371	Target Neighborhood Hits	583	Shared Neighborhood Hits	414
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

DYHC_HUMAN
NC score	0.261902 (rank : 653)	θ value	0.000602161 (rank : 464)
Query Neighborhood Hits	1371	Target Neighborhood Hits	733	Shared Neighborhood Hits	481
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

GFAP_HUMAN
NC score	0.261330 (rank : 654)	θ value	0.00298849 (rank : 550)
Query Neighborhood Hits	1371	Target Neighborhood Hits	723	Shared Neighborhood Hits	522
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

KIF3A_HUMAN
NC score	0.261165 (rank : 655)	θ value	0.0563607 (rank : 731)
Query Neighborhood Hits	1371	Target Neighborhood Hits	704	Shared Neighborhood Hits	504
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

DYHC_MOUSE
NC score	0.261127 (rank : 656)	θ value	0.000602161 (rank : 465)
Query Neighborhood Hits	1371	Target Neighborhood Hits	729	Shared Neighborhood Hits	482
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

PLCB1_HUMAN
NC score	0.260406 (rank : 657)	θ value	1.81305 (rank : 1106)
Query Neighborhood Hits	1371	Target Neighborhood Hits	614	Shared Neighborhood Hits	411
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

VIME_HUMAN
NC score	0.259602 (rank : 658)	θ value	0.000602161 (rank : 474)
Query Neighborhood Hits	1371	Target Neighborhood Hits	706	Shared Neighborhood Hits	518
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

SEC20_MOUSE
NC score	0.259423 (rank : 659)	θ value	θ > 10 (rank : 2123)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	264
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

AMOL1_HUMAN
NC score	0.259151 (rank : 660)	θ value	3.0926 (rank : 1164)
Query Neighborhood Hits	1371	Target Neighborhood Hits	435	Shared Neighborhood Hits	326
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

CDC37_MOUSE
NC score	0.258447 (rank : 661)	θ value	0.163984 (rank : 824)
Query Neighborhood Hits	1371	Target Neighborhood Hits	359	Shared Neighborhood Hits	289
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

EFS_HUMAN
NC score	0.258115 (rank : 662)	θ value	0.0330416 (rank : 697)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	176
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

BCN1_HUMAN
NC score	0.257489 (rank : 663)	θ value	θ > 10 (rank : 1445)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	326
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

KIFC1_HUMAN
NC score	0.257352 (rank : 664)	θ value	0.00175202 (rank : 517)
Query Neighborhood Hits	1371	Target Neighborhood Hits	545	Shared Neighborhood Hits	407
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

LRSM1_MOUSE
NC score	0.257323 (rank : 665)	θ value	0.00035302 (rank : 447)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	422
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MMRN2_HUMAN
NC score	0.257083 (rank : 666)	θ value	θ > 10 (rank : 1917)
Query Neighborhood Hits	1371	Target Neighborhood Hits	400	Shared Neighborhood Hits	259
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

ABR_HUMAN
NC score	0.257028 (rank : 667)	θ value	2.44474e-05 (rank : 339)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	93
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

MYO6_MOUSE
NC score	0.257011 (rank : 668)	θ value	0.00175202 (rank : 520)
Query Neighborhood Hits	1371	Target Neighborhood Hits	586	Shared Neighborhood Hits	443
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

LETM1_HUMAN
NC score	0.256743 (rank : 669)	θ value	θ > 10 (rank : 1877)
Query Neighborhood Hits	1371	Target Neighborhood Hits	338	Shared Neighborhood Hits	264
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

CASL_HUMAN
NC score	0.256570 (rank : 670)	θ value	0.000461057 (rank : 452)
Query Neighborhood Hits	1371	Target Neighborhood Hits	259	Shared Neighborhood Hits	168
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

GFAP_MOUSE
NC score	0.256424 (rank : 671)	θ value	0.00134147 (rank : 502)
Query Neighborhood Hits	1371	Target Neighborhood Hits	725	Shared Neighborhood Hits	523
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

KIF14_HUMAN
NC score	0.256127 (rank : 672)	θ value	3.41135e-07 (rank : 194)
Query Neighborhood Hits	1371	Target Neighborhood Hits	732	Shared Neighborhood Hits	498
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

EHD1_HUMAN
NC score	0.255546 (rank : 673)	θ value	1.29331e-14 (rank : 51)
Query Neighborhood Hits	1371	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4M9, O14611, Q9UNR3	Gene names	EHD1, PAST, PAST1
Domain Architecture
Description	EH-domain-containing protein 1 (Testilin) (hPAST1).

EHD1_MOUSE
NC score	0.255342 (rank : 674)	θ value	1.68911e-14 (rank : 52)
Query Neighborhood Hits	1371	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WVK4	Gene names	Ehd1, Past1
Domain Architecture
Description	EH-domain-containing protein 1 (mPAST1).

EHD2_HUMAN
NC score	0.254964 (rank : 675)	θ value	7.58209e-15 (rank : 49)
Query Neighborhood Hits	1371	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZN4, Q96CB6	Gene names	EHD2
Domain Architecture
Description	EH-domain-containing protein 2.

TEKT1_HUMAN
NC score	0.254729 (rank : 676)	θ value	0.279714 (rank : 892)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	251
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

KI21B_MOUSE
NC score	0.254498 (rank : 677)	θ value	0.0252991 (rank : 679)
Query Neighborhood Hits	1371	Target Neighborhood Hits	997	Shared Neighborhood Hits	495
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

SKI_MOUSE
NC score	0.254277 (rank : 678)	θ value	3.0926 (rank : 1186)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	324
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

KI21B_HUMAN
NC score	0.254176 (rank : 679)	θ value	0.0252991 (rank : 678)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1017	Shared Neighborhood Hits	501
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

PHLB1_MOUSE
NC score	0.254164 (rank : 680)	θ value	6.88961 (rank : 1309)
Query Neighborhood Hits	1371	Target Neighborhood Hits	678	Shared Neighborhood Hits	361
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RIMB2_MOUSE
NC score	0.253919 (rank : 681)	θ value	0.00228821 (rank : 538)
Query Neighborhood Hits	1371	Target Neighborhood Hits	246	Shared Neighborhood Hits	158
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

NOXO1_HUMAN
NC score	0.253913 (rank : 682)	θ value	7.1131e-05 (rank : 385)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

CASL_MOUSE
NC score	0.253827 (rank : 683)	θ value	0.000602161 (rank : 462)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	166
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

U2AFL_HUMAN
NC score	0.253624 (rank : 684)	θ value	1.38821 (rank : 1074)
Query Neighborhood Hits	1371	Target Neighborhood Hits	503	Shared Neighborhood Hits	368
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

NUP88_HUMAN
NC score	0.253551 (rank : 685)	θ value	0.0148317 (rank : 648)
Query Neighborhood Hits	1371	Target Neighborhood Hits	354	Shared Neighborhood Hits	290
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

EHD4_MOUSE
NC score	0.253263 (rank : 686)	θ value	9.26847e-13 (rank : 72)
Query Neighborhood Hits	1371	Target Neighborhood Hits	40	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQP2	Gene names	Ehd4, Past2
Domain Architecture
Description	EH-domain-containing protein 4 (mPAST2).

LBN_HUMAN
NC score	0.252456 (rank : 687)	θ value	θ > 10 (rank : 1870)
Query Neighborhood Hits	1371	Target Neighborhood Hits	308	Shared Neighborhood Hits	246
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

PEX13_MOUSE
NC score	0.252441 (rank : 688)	θ value	0.00298849 (rank : 557)
Query Neighborhood Hits	1371	Target Neighborhood Hits	126	Shared Neighborhood Hits	118
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

EHD3_MOUSE
NC score	0.252122 (rank : 689)	θ value	1.09485e-13 (rank : 59)
Query Neighborhood Hits	1371	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXY6	Gene names	Ehd3, Ehd2
Domain Architecture
Description	EH-domain-containing protein 3.

EHD3_HUMAN
NC score	0.251607 (rank : 690)	θ value	4.16044e-13 (rank : 65)
Query Neighborhood Hits	1371	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZN3, Q8N514, Q9NZB3	Gene names	EHD3, EHD2
Domain Architecture
Description	EH-domain-containing protein 3.

SRGP2_MOUSE
NC score	0.251515 (rank : 691)	θ value	4.92598e-06 (rank : 280)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	232
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

TNNT3_HUMAN
NC score	0.251509 (rank : 692)	θ value	θ > 10 (rank : 2284)
Query Neighborhood Hits	1371	Target Neighborhood Hits	327	Shared Neighborhood Hits	264
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

NUCB2_MOUSE
NC score	0.251277 (rank : 693)	θ value	0.0563607 (rank : 732)
Query Neighborhood Hits	1371	Target Neighborhood Hits	459	Shared Neighborhood Hits	311
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

APOE_MOUSE
NC score	0.251151 (rank : 694)	θ value	θ > 10 (rank : 1423)
Query Neighborhood Hits	1371	Target Neighborhood Hits	319	Shared Neighborhood Hits	246
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

ANM2_HUMAN
NC score	0.250756 (rank : 695)	θ value	5.81887e-07 (rank : 208)
Query Neighborhood Hits	1371	Target Neighborhood Hits	175	Shared Neighborhood Hits	157
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

PCLO_HUMAN
NC score	0.250126 (rank : 696)	θ value	1.69304e-06 (rank : 240)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2046	Shared Neighborhood Hits	509
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CLC4F_MOUSE
NC score	0.249604 (rank : 697)	θ value	θ > 10 (rank : 1530)
Query Neighborhood Hits	1371	Target Neighborhood Hits	572	Shared Neighborhood Hits	334
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

PEX13_HUMAN
NC score	0.249175 (rank : 698)	θ value	0.0252991 (rank : 688)
Query Neighborhood Hits	1371	Target Neighborhood Hits	128	Shared Neighborhood Hits	116
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

CJ068_HUMAN
NC score	0.248901 (rank : 699)	θ value	0.0330416 (rank : 695)
Query Neighborhood Hits	1371	Target Neighborhood Hits	316	Shared Neighborhood Hits	194
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

FGD5_HUMAN
NC score	0.248443 (rank : 700)	θ value	3.19293e-05 (rank : 350)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

HC127_HUMAN
NC score	0.247808 (rank : 701)	θ value	θ > 10 (rank : 1713)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	245
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
NC score	0.247808 (rank : 702)	θ value	θ > 10 (rank : 1714)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	245
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

SRGP2_HUMAN
NC score	0.247535 (rank : 703)	θ value	1.69304e-06 (rank : 243)
Query Neighborhood Hits	1371	Target Neighborhood Hits	331	Shared Neighborhood Hits	226
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

IDLC_HUMAN
NC score	0.247187 (rank : 704)	θ value	0.62314 (rank : 963)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	264
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

GCP60_HUMAN
NC score	0.246708 (rank : 705)	θ value	8.99809 (rank : 1331)
Query Neighborhood Hits	1371	Target Neighborhood Hits	419	Shared Neighborhood Hits	307
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

EHD4_HUMAN
NC score	0.246387 (rank : 706)	θ value	1.25267e-09 (rank : 116)
Query Neighborhood Hits	1371	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H223, Q9HAR1, Q9NZN2	Gene names	EHD4, HCA10, HCA11
Domain Architecture
Description	EH-domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11).

WDR67_MOUSE
NC score	0.246343 (rank : 707)	θ value	8.99809 (rank : 1368)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	291
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

STMN2_HUMAN
NC score	0.245940 (rank : 708)	θ value	0.0961366 (rank : 793)
Query Neighborhood Hits	1371	Target Neighborhood Hits	458	Shared Neighborhood Hits	325
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
NC score	0.245940 (rank : 709)	θ value	0.0961366 (rank : 794)
Query Neighborhood Hits	1371	Target Neighborhood Hits	458	Shared Neighborhood Hits	325
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

SKI_HUMAN
NC score	0.245472 (rank : 710)	θ value	5.27518 (rank : 1267)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	335
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

PLCB1_MOUSE
NC score	0.245261 (rank : 711)	θ value	1.81305 (rank : 1107)
Query Neighborhood Hits	1371	Target Neighborhood Hits	531	Shared Neighborhood Hits	376
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

P55G_HUMAN
NC score	0.245050 (rank : 712)	θ value	0.00869519 (rank : 614)
Query Neighborhood Hits	1371	Target Neighborhood Hits	451	Shared Neighborhood Hits	321
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

ZRF1_MOUSE
NC score	0.244659 (rank : 713)	θ value	5.27518 (rank : 1278)
Query Neighborhood Hits	1371	Target Neighborhood Hits	414	Shared Neighborhood Hits	283
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

STK10_MOUSE
NC score	0.244372 (rank : 714)	θ value	4.91457e-14 (rank : 56)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2132	Shared Neighborhood Hits	750
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

LBN_MOUSE
NC score	0.244315 (rank : 715)	θ value	θ > 10 (rank : 1871)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	250
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

CTTB2_HUMAN
NC score	0.244307 (rank : 716)	θ value	0.00509761 (rank : 581)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1061	Shared Neighborhood Hits	525
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

BCN1_MOUSE
NC score	0.244230 (rank : 717)	θ value	θ > 10 (rank : 1446)
Query Neighborhood Hits	1371	Target Neighborhood Hits	367	Shared Neighborhood Hits	299
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

RIMB2_HUMAN
NC score	0.244083 (rank : 718)	θ value	0.000461057 (rank : 459)
Query Neighborhood Hits	1371	Target Neighborhood Hits	263	Shared Neighborhood Hits	152
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

TRDN_HUMAN
NC score	0.242776 (rank : 719)	θ value	1.81305 (rank : 1116)
Query Neighborhood Hits	1371	Target Neighborhood Hits	542	Shared Neighborhood Hits	256
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

RBP1_HUMAN
NC score	0.242349 (rank : 720)	θ value	θ > 10 (rank : 2068)
Query Neighborhood Hits	1371	Target Neighborhood Hits	521	Shared Neighborhood Hits	370
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CENPK_HUMAN
NC score	0.242332 (rank : 721)	θ value	0.0961366 (rank : 777)
Query Neighborhood Hits	1371	Target Neighborhood Hits	273	Shared Neighborhood Hits	224
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

CCDC7_HUMAN
NC score	0.241824 (rank : 722)	θ value	θ > 10 (rank : 1491)
Query Neighborhood Hits	1371	Target Neighborhood Hits	253	Shared Neighborhood Hits	201
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

GCP60_MOUSE
NC score	0.241394 (rank : 723)	θ value	θ > 10 (rank : 1694)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	295
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

ANM2_MOUSE
NC score	0.241348 (rank : 724)	θ value	9.92553e-07 (rank : 221)
Query Neighborhood Hits	1371	Target Neighborhood Hits	175	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

NOP14_HUMAN
NC score	0.240735 (rank : 725)	θ value	0.0113563 (rank : 629)
Query Neighborhood Hits	1371	Target Neighborhood Hits	573	Shared Neighborhood Hits	328
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

DZIP1_MOUSE
NC score	0.240620 (rank : 726)	θ value	1.06291 (rank : 1012)
Query Neighborhood Hits	1371	Target Neighborhood Hits	530	Shared Neighborhood Hits	236
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

DREB_MOUSE
NC score	0.240371 (rank : 727)	θ value	4.03905 (rank : 1204)
Query Neighborhood Hits	1371	Target Neighborhood Hits	446	Shared Neighborhood Hits	301
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

COVA1_MOUSE
NC score	0.239648 (rank : 728)	θ value	θ > 10 (rank : 1544)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	228
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

TNNT3_MOUSE
NC score	0.239628 (rank : 729)	θ value	θ > 10 (rank : 2285)
Query Neighborhood Hits	1371	Target Neighborhood Hits	317	Shared Neighborhood Hits	243
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

CENPH_MOUSE
NC score	0.238924 (rank : 730)	θ value	0.47712 (rank : 935)
Query Neighborhood Hits	1371	Target Neighborhood Hits	195	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

AFAD_HUMAN
NC score	0.238016 (rank : 731)	θ value	0.163984 (rank : 819)
Query Neighborhood Hits	1371	Target Neighborhood Hits	689	Shared Neighborhood Hits	353
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PRC1_HUMAN
NC score	0.237727 (rank : 732)	θ value	8.99809 (rank : 1355)
Query Neighborhood Hits	1371	Target Neighborhood Hits	328	Shared Neighborhood Hits	259
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

CT116_HUMAN
NC score	0.237614 (rank : 733)	θ value	θ > 10 (rank : 1553)
Query Neighborhood Hits	1371	Target Neighborhood Hits	294	Shared Neighborhood Hits	232
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

SFR12_HUMAN
NC score	0.237487 (rank : 734)	θ value	θ > 10 (rank : 2130)
Query Neighborhood Hits	1371	Target Neighborhood Hits	553	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SAFB2_MOUSE
NC score	0.236947 (rank : 735)	θ value	θ > 10 (rank : 2111)
Query Neighborhood Hits	1371	Target Neighborhood Hits	581	Shared Neighborhood Hits	348
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

CUTL2_HUMAN
NC score	0.236075 (rank : 736)	θ value	θ > 10 (rank : 1561)
Query Neighborhood Hits	1371	Target Neighborhood Hits	906	Shared Neighborhood Hits	356
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DREB_HUMAN
NC score	0.236035 (rank : 737)	θ value	6.88961 (rank : 1296)
Query Neighborhood Hits	1371	Target Neighborhood Hits	450	Shared Neighborhood Hits	307
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

P85A_HUMAN
NC score	0.235898 (rank : 738)	θ value	0.21417 (rank : 857)
Query Neighborhood Hits	1371	Target Neighborhood Hits	479	Shared Neighborhood Hits	312
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

STMN4_HUMAN
NC score	0.235539 (rank : 739)	θ value	0.000121331 (rank : 404)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	291
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
NC score	0.235457 (rank : 740)	θ value	0.000121331 (rank : 405)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	291
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

NUCB1_MOUSE
NC score	0.234491 (rank : 741)	θ value	0.813845 (rank : 988)
Query Neighborhood Hits	1371	Target Neighborhood Hits	414	Shared Neighborhood Hits	293
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

SPC24_HUMAN
NC score	0.234097 (rank : 742)	θ value	θ > 10 (rank : 2177)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	261
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

RUSC1_HUMAN
NC score	0.234015 (rank : 743)	θ value	0.00228821 (rank : 539)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

TARA_HUMAN
NC score	0.233163 (rank : 744)	θ value	0.0330416 (rank : 703)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1626	Shared Neighborhood Hits	478
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MERL_MOUSE
NC score	0.233036 (rank : 745)	θ value	1.06291 (rank : 1020)
Query Neighborhood Hits	1371	Target Neighborhood Hits	524	Shared Neighborhood Hits	392
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

HAP1_MOUSE
NC score	0.232783 (rank : 746)	θ value	θ > 10 (rank : 1712)
Query Neighborhood Hits	1371	Target Neighborhood Hits	388	Shared Neighborhood Hits	270
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

MERL_HUMAN
NC score	0.232474 (rank : 747)	θ value	1.38821 (rank : 1058)
Query Neighborhood Hits	1371	Target Neighborhood Hits	532	Shared Neighborhood Hits	392
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

SPTB1_MOUSE
NC score	0.232343 (rank : 748)	θ value	θ > 10 (rank : 2180)
Query Neighborhood Hits	1371	Target Neighborhood Hits	543	Shared Neighborhood Hits	376
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

IDLC_MOUSE
NC score	0.231962 (rank : 749)	θ value	0.47712 (rank : 940)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	243
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

IASPP_HUMAN
NC score	0.231684 (rank : 750)	θ value	5.44631e-05 (rank : 372)
Query Neighborhood Hits	1371	Target Neighborhood Hits	688	Shared Neighborhood Hits	207
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

FA62A_HUMAN
NC score	0.230505 (rank : 751)	θ value	1.06045e-08 (rank : 136)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

K2C1_HUMAN
NC score	0.230277 (rank : 752)	θ value	0.0193708 (rank : 666)
Query Neighborhood Hits	1371	Target Neighborhood Hits	624	Shared Neighborhood Hits	423
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

FA50A_MOUSE
NC score	0.229981 (rank : 753)	θ value	θ > 10 (rank : 1652)
Query Neighborhood Hits	1371	Target Neighborhood Hits	293	Shared Neighborhood Hits	251
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

TRIO_HUMAN
NC score	0.229548 (rank : 754)	θ value	5.26297e-08 (rank : 169)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1580	Shared Neighborhood Hits	447
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

FA62A_MOUSE
NC score	0.229511 (rank : 755)	θ value	2.79066e-09 (rank : 125)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	92
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

NUCB2_HUMAN
NC score	0.229478 (rank : 756)	θ value	0.813845 (rank : 989)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	232
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

FGD5_MOUSE
NC score	0.228954 (rank : 757)	θ value	5.44631e-05 (rank : 371)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	67
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

STMN3_HUMAN
NC score	0.228826 (rank : 758)	θ value	0.365318 (rank : 925)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	285
SwissProt Accessions	Q9NZ72, O75527, Q969Y4	Gene names	STMN3, SCLIP
Domain Architecture
Description	Stathmin-3 (SCG10-like protein).

DIAP1_MOUSE
NC score	0.228294 (rank : 759)	θ value	0.47712 (rank : 937)
Query Neighborhood Hits	1371	Target Neighborhood Hits	839	Shared Neighborhood Hits	433
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

AMOL1_MOUSE
NC score	0.227506 (rank : 760)	θ value	θ > 10 (rank : 1399)
Query Neighborhood Hits	1371	Target Neighborhood Hits	445	Shared Neighborhood Hits	306
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

BI2L1_HUMAN
NC score	0.227023 (rank : 761)	θ value	1.87187e-05 (rank : 324)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

A20A4_HUMAN
NC score	0.227021 (rank : 762)	θ value	0.0961366 (rank : 771)
Query Neighborhood Hits	1371	Target Neighborhood Hits	710	Shared Neighborhood Hits	364
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

PKHG4_HUMAN
NC score	0.227017 (rank : 763)	θ value	θ > 10 (rank : 2028)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	72
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

CCD22_MOUSE
NC score	0.226826 (rank : 764)	θ value	θ > 10 (rank : 1477)
Query Neighborhood Hits	1371	Target Neighborhood Hits	268	Shared Neighborhood Hits	206
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

ES8L3_MOUSE
NC score	0.226470 (rank : 765)	θ value	0.00102713 (rank : 495)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	149
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ZRF1_HUMAN
NC score	0.226245 (rank : 766)	θ value	θ > 10 (rank : 2357)
Query Neighborhood Hits	1371	Target Neighborhood Hits	457	Shared Neighborhood Hits	291
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

SH24A_HUMAN
NC score	0.226226 (rank : 767)	θ value	0.47712 (rank : 949)
Query Neighborhood Hits	1371	Target Neighborhood Hits	455	Shared Neighborhood Hits	278
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

KIF3B_HUMAN
NC score	0.225599 (rank : 768)	θ value	0.00869519 (rank : 609)
Query Neighborhood Hits	1371	Target Neighborhood Hits	540	Shared Neighborhood Hits	408
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

P55G_MOUSE
NC score	0.225400 (rank : 769)	θ value	0.0113563 (rank : 630)
Query Neighborhood Hits	1371	Target Neighborhood Hits	401	Shared Neighborhood Hits	275
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

RBP1_MOUSE
NC score	0.225125 (rank : 770)	θ value	θ > 10 (rank : 2069)
Query Neighborhood Hits	1371	Target Neighborhood Hits	493	Shared Neighborhood Hits	344
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

STIM2_HUMAN
NC score	0.224448 (rank : 771)	θ value	2.36792 (rank : 1160)
Query Neighborhood Hits	1371	Target Neighborhood Hits	420	Shared Neighborhood Hits	322
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

ACINU_MOUSE
NC score	0.224337 (rank : 772)	θ value	0.47712 (rank : 929)
Query Neighborhood Hits	1371	Target Neighborhood Hits	712	Shared Neighborhood Hits	335
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SPC25_HUMAN
NC score	0.224024 (rank : 773)	θ value	0.62314 (rank : 974)
Query Neighborhood Hits	1371	Target Neighborhood Hits	273	Shared Neighborhood Hits	217
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

YO11_MOUSE
NC score	0.223361 (rank : 774)	θ value	θ > 10 (rank : 2339)
Query Neighborhood Hits	1371	Target Neighborhood Hits	272	Shared Neighborhood Hits	215
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

ENAH_MOUSE
NC score	0.222810 (rank : 775)	θ value	0.0736092 (rank : 754)
Query Neighborhood Hits	1371	Target Neighborhood Hits	919	Shared Neighborhood Hits	388
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PPIP2_MOUSE
NC score	0.222690 (rank : 776)	θ value	5.27518 (rank : 1258)
Query Neighborhood Hits	1371	Target Neighborhood Hits	308	Shared Neighborhood Hits	244
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PPIP2_HUMAN
NC score	0.222499 (rank : 777)	θ value	1.06291 (rank : 1027)
Query Neighborhood Hits	1371	Target Neighborhood Hits	254	Shared Neighborhood Hits	212
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

BEGIN_HUMAN
NC score	0.222305 (rank : 778)	θ value	θ > 10 (rank : 1447)
Query Neighborhood Hits	1371	Target Neighborhood Hits	454	Shared Neighborhood Hits	315
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CTGE4_HUMAN
NC score	0.222019 (rank : 779)	θ value	0.0563607 (rank : 727)
Query Neighborhood Hits	1371	Target Neighborhood Hits	393	Shared Neighborhood Hits	277
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

BAZ2B_HUMAN
NC score	0.221976 (rank : 780)	θ value	θ > 10 (rank : 1440)
Query Neighborhood Hits	1371	Target Neighborhood Hits	803	Shared Neighborhood Hits	396
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

P85A_MOUSE
NC score	0.221960 (rank : 781)	θ value	0.365318 (rank : 920)
Query Neighborhood Hits	1371	Target Neighborhood Hits	435	Shared Neighborhood Hits	271
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CROP_HUMAN
NC score	0.221423 (rank : 782)	θ value	6.88961 (rank : 1291)
Query Neighborhood Hits	1371	Target Neighborhood Hits	402	Shared Neighborhood Hits	269
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

LAMA2_MOUSE
NC score	0.221159 (rank : 783)	θ value	0.00298849 (rank : 551)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1198	Shared Neighborhood Hits	454
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ANR12_HUMAN
NC score	0.221152 (rank : 784)	θ value	0.163984 (rank : 820)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1081	Shared Neighborhood Hits	425
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

GP73_HUMAN
NC score	0.221124 (rank : 785)	θ value	5.27518 (rank : 1246)
Query Neighborhood Hits	1371	Target Neighborhood Hits	309	Shared Neighborhood Hits	230
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

WTAP_HUMAN
NC score	0.220684 (rank : 786)	θ value	θ > 10 (rank : 2330)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	203
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

KIF3B_MOUSE
NC score	0.220450 (rank : 787)	θ value	0.0113563 (rank : 623)
Query Neighborhood Hits	1371	Target Neighborhood Hits	533	Shared Neighborhood Hits	399
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

SDPR_MOUSE
NC score	0.219564 (rank : 788)	θ value	θ > 10 (rank : 2119)
Query Neighborhood Hits	1371	Target Neighborhood Hits	485	Shared Neighborhood Hits	273
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

A20A1_HUMAN
NC score	0.219028 (rank : 789)	θ value	0.21417 (rank : 840)
Query Neighborhood Hits	1371	Target Neighborhood Hits	698	Shared Neighborhood Hits	354
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

MAP1B_MOUSE
NC score	0.218946 (rank : 790)	θ value	2.36792 (rank : 1147)
Query Neighborhood Hits	1371	Target Neighborhood Hits	977	Shared Neighborhood Hits	363
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

STMN3_MOUSE
NC score	0.218937 (rank : 791)	θ value	0.125558 (rank : 815)
Query Neighborhood Hits	1371	Target Neighborhood Hits	331	Shared Neighborhood Hits	270
SwissProt Accessions	O70166	Gene names	Stmn3, Sclip
Domain Architecture
Description	Stathmin-3 (SCG10-like protein) (SCG10-related protein HiAT3) (Hippocampus abundant transcript 3).

A20A3_HUMAN
NC score	0.218607 (rank : 792)	θ value	0.279714 (rank : 871)
Query Neighborhood Hits	1371	Target Neighborhood Hits	692	Shared Neighborhood Hits	352
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

PCLO_MOUSE
NC score	0.218444 (rank : 793)	θ value	8.40245e-06 (rank : 294)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2275	Shared Neighborhood Hits	503
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

A20A2_HUMAN
NC score	0.218214 (rank : 794)	θ value	0.0563607 (rank : 719)
Query Neighborhood Hits	1371	Target Neighborhood Hits	716	Shared Neighborhood Hits	362
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ES8L3_HUMAN
NC score	0.217412 (rank : 795)	θ value	0.000602161 (rank : 466)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

GBP4_HUMAN
NC score	0.217406 (rank : 796)	θ value	0.21417 (rank : 843)
Query Neighborhood Hits	1371	Target Neighborhood Hits	484	Shared Neighborhood Hits	354
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

RUSC1_MOUSE
NC score	0.217197 (rank : 797)	θ value	0.00665767 (rank : 600)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	142
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

STIM2_MOUSE
NC score	0.217084 (rank : 798)	θ value	1.38821 (rank : 1070)
Query Neighborhood Hits	1371	Target Neighborhood Hits	403	Shared Neighborhood Hits	313
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

KIF11_MOUSE
NC score	0.216448 (rank : 799)	θ value	0.0431538 (rank : 713)
Query Neighborhood Hits	1371	Target Neighborhood Hits	446	Shared Neighborhood Hits	327
SwissProt Accessions	Q6P9P6, Q9Z1J0	Gene names	Kif11
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5).

DZIP1_HUMAN
NC score	0.216054 (rank : 800)	θ value	θ > 10 (rank : 1605)
Query Neighborhood Hits	1371	Target Neighborhood Hits	675	Shared Neighborhood Hits	256
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

STK10_HUMAN
NC score	0.215934 (rank : 801)	θ value	1.38499e-08 (rank : 145)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1921	Shared Neighborhood Hits	699
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

CROP_MOUSE
NC score	0.215718 (rank : 802)	θ value	6.88961 (rank : 1292)
Query Neighborhood Hits	1371	Target Neighborhood Hits	403	Shared Neighborhood Hits	268
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

BAP29_HUMAN
NC score	0.215482 (rank : 803)	θ value	5.27518 (rank : 1232)
Query Neighborhood Hits	1371	Target Neighborhood Hits	362	Shared Neighborhood Hits	274
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

WTAP_MOUSE
NC score	0.215436 (rank : 804)	θ value	θ > 10 (rank : 2331)
Query Neighborhood Hits	1371	Target Neighborhood Hits	250	Shared Neighborhood Hits	199
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

SNX18_MOUSE
NC score	0.215311 (rank : 805)	θ value	0.0736092 (rank : 766)
Query Neighborhood Hits	1371	Target Neighborhood Hits	198	Shared Neighborhood Hits	139
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

IASPP_MOUSE
NC score	0.214795 (rank : 806)	θ value	4.1701e-05 (rank : 356)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1024	Shared Neighborhood Hits	236
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SPTB1_HUMAN
NC score	0.214021 (rank : 807)	θ value	θ > 10 (rank : 2179)
Query Neighborhood Hits	1371	Target Neighborhood Hits	541	Shared Neighborhood Hits	380
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTN5_HUMAN
NC score	0.212934 (rank : 808)	θ value	θ > 10 (rank : 2183)
Query Neighborhood Hits	1371	Target Neighborhood Hits	674	Shared Neighborhood Hits	416
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

RNF8_HUMAN
NC score	0.212896 (rank : 809)	θ value	θ > 10 (rank : 2096)
Query Neighborhood Hits	1371	Target Neighborhood Hits	622	Shared Neighborhood Hits	306
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RHG26_HUMAN
NC score	0.212836 (rank : 810)	θ value	1.87187e-05 (rank : 336)
Query Neighborhood Hits	1371	Target Neighborhood Hits	281	Shared Neighborhood Hits	184
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

CT116_MOUSE
NC score	0.212350 (rank : 811)	θ value	θ > 10 (rank : 1554)
Query Neighborhood Hits	1371	Target Neighborhood Hits	268	Shared Neighborhood Hits	200
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

CLUA1_MOUSE
NC score	0.212236 (rank : 812)	θ value	θ > 10 (rank : 1536)
Query Neighborhood Hits	1371	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

KIF3C_HUMAN
NC score	0.211530 (rank : 813)	θ value	8.99809 (rank : 1338)
Query Neighborhood Hits	1371	Target Neighborhood Hits	478	Shared Neighborhood Hits	370
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

SNX18_HUMAN
NC score	0.211260 (rank : 814)	θ value	0.0563607 (rank : 738)
Query Neighborhood Hits	1371	Target Neighborhood Hits	207	Shared Neighborhood Hits	143
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

IMMT_MOUSE
NC score	0.211112 (rank : 815)	θ value	θ > 10 (rank : 1742)
Query Neighborhood Hits	1371	Target Neighborhood Hits	326	Shared Neighborhood Hits	241
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

K2C8_HUMAN
NC score	0.211087 (rank : 816)	θ value	θ > 10 (rank : 1802)
Query Neighborhood Hits	1371	Target Neighborhood Hits	593	Shared Neighborhood Hits	424
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

K2C8_MOUSE
NC score	0.210977 (rank : 817)	θ value	θ > 10 (rank : 1803)
Query Neighborhood Hits	1371	Target Neighborhood Hits	576	Shared Neighborhood Hits	418
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

K0494_MOUSE
NC score	0.210488 (rank : 818)	θ value	8.99809 (rank : 1335)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	179
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

TAOK1_HUMAN
NC score	0.210299 (rank : 819)	θ value	1.53129e-07 (rank : 181)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1734	Shared Neighborhood Hits	638
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

CN045_HUMAN
NC score	0.210161 (rank : 820)	θ value	θ > 10 (rank : 1539)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	183
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

TAOK1_MOUSE
NC score	0.210042 (rank : 821)	θ value	1.99992e-07 (rank : 186)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1720	Shared Neighborhood Hits	636
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

RILP_MOUSE
NC score	0.210020 (rank : 822)	θ value	θ > 10 (rank : 2082)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	205
SwissProt Accessions	Q5ND29, Q80WB8, Q8CHY9	Gene names	Rilp
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

CUTL2_MOUSE
NC score	0.209739 (rank : 823)	θ value	θ > 10 (rank : 1562)
Query Neighborhood Hits	1371	Target Neighborhood Hits	771	Shared Neighborhood Hits	313
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

K1HA_HUMAN
NC score	0.209698 (rank : 824)	θ value	0.0736092 (rank : 758)
Query Neighborhood Hits	1371	Target Neighborhood Hits	502	Shared Neighborhood Hits	378
SwissProt Accessions	O76009	Gene names	KRTHA3A, HHA3-I, HKA3A
Domain Architecture
Description	Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I).

SYGP1_HUMAN
NC score	0.208107 (rank : 825)	θ value	0.163984 (rank : 834)
Query Neighborhood Hits	1371	Target Neighborhood Hits	589	Shared Neighborhood Hits	398
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

KIF3C_MOUSE
NC score	0.207848 (rank : 826)	θ value	θ > 10 (rank : 1825)
Query Neighborhood Hits	1371	Target Neighborhood Hits	468	Shared Neighborhood Hits	364
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

K0494_HUMAN
NC score	0.207827 (rank : 827)	θ value	θ > 10 (rank : 1767)
Query Neighborhood Hits	1371	Target Neighborhood Hits	230	Shared Neighborhood Hits	180
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

JIP4_HUMAN
NC score	0.206885 (rank : 828)	θ value	θ > 10 (rank : 1764)
Query Neighborhood Hits	1371	Target Neighborhood Hits	585	Shared Neighborhood Hits	366
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

ACINU_HUMAN
NC score	0.206041 (rank : 829)	θ value	1.06291 (rank : 1002)
Query Neighborhood Hits	1371	Target Neighborhood Hits	828	Shared Neighborhood Hits	352
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DDEF1_MOUSE
NC score	0.205303 (rank : 830)	θ value	1.09739e-05 (rank : 299)
Query Neighborhood Hits	1371	Target Neighborhood Hits	592	Shared Neighborhood Hits	221
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

T2_MOUSE
NC score	0.205087 (rank : 831)	θ value	θ > 10 (rank : 2239)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	101
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

BAIP2_MOUSE
NC score	0.204534 (rank : 832)	θ value	0.000786445 (rank : 475)
Query Neighborhood Hits	1371	Target Neighborhood Hits	185	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

NFL_HUMAN
NC score	0.204114 (rank : 833)	θ value	1.81305 (rank : 1103)
Query Neighborhood Hits	1371	Target Neighborhood Hits	666	Shared Neighborhood Hits	426
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NFL_MOUSE
NC score	0.204036 (rank : 834)	θ value	0.365318 (rank : 916)
Query Neighborhood Hits	1371	Target Neighborhood Hits	695	Shared Neighborhood Hits	441
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

FA50A_HUMAN
NC score	0.203869 (rank : 835)	θ value	θ > 10 (rank : 1651)
Query Neighborhood Hits	1371	Target Neighborhood Hits	264	Shared Neighborhood Hits	224
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

CCD38_HUMAN
NC score	0.203707 (rank : 836)	θ value	0.62314 (rank : 960)
Query Neighborhood Hits	1371	Target Neighborhood Hits	287	Shared Neighborhood Hits	222
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

BEGIN_MOUSE
NC score	0.202720 (rank : 837)	θ value	θ > 10 (rank : 1448)
Query Neighborhood Hits	1371	Target Neighborhood Hits	383	Shared Neighborhood Hits	285
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BAIP2_HUMAN
NC score	0.202007 (rank : 838)	θ value	0.000270298 (rank : 425)
Query Neighborhood Hits	1371	Target Neighborhood Hits	192	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

LETM1_MOUSE
NC score	0.201940 (rank : 839)	θ value	θ > 10 (rank : 1878)
Query Neighborhood Hits	1371	Target Neighborhood Hits	240	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

RASL2_HUMAN
NC score	0.201362 (rank : 840)	θ value	1.38499e-08 (rank : 142)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	97
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

CCD22_HUMAN
NC score	0.201254 (rank : 841)	θ value	3.0926 (rank : 1167)
Query Neighborhood Hits	1371	Target Neighborhood Hits	242	Shared Neighborhood Hits	185
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

BI2L1_MOUSE
NC score	0.200882 (rank : 842)	θ value	1.87187e-05 (rank : 325)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	124
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

FBX41_MOUSE
NC score	0.200480 (rank : 843)	θ value	θ > 10 (rank : 1666)
Query Neighborhood Hits	1371	Target Neighborhood Hits	430	Shared Neighborhood Hits	269
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

K1H4_HUMAN
NC score	0.199460 (rank : 844)	θ value	0.21417 (rank : 847)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	355
SwissProt Accessions	O76011	Gene names	KRTHA4, HHA4, HKA4
Domain Architecture
Description	Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4).

U2AFL_MOUSE
NC score	0.199005 (rank : 845)	θ value	1.38821 (rank : 1075)
Query Neighborhood Hits	1371	Target Neighborhood Hits	389	Shared Neighborhood Hits	286
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

CENPU_HUMAN
NC score	0.198806 (rank : 846)	θ value	θ > 10 (rank : 1505)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	215
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CASC5_HUMAN
NC score	0.197851 (rank : 847)	θ value	θ > 10 (rank : 1471)
Query Neighborhood Hits	1371	Target Neighborhood Hits	376	Shared Neighborhood Hits	258
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

FBX41_HUMAN
NC score	0.197428 (rank : 848)	θ value	θ > 10 (rank : 1665)
Query Neighborhood Hits	1371	Target Neighborhood Hits	475	Shared Neighborhood Hits	273
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

DOC2B_MOUSE
NC score	0.197422 (rank : 849)	θ value	7.59969e-07 (rank : 218)
Query Neighborhood Hits	1371	Target Neighborhood Hits	169	Shared Neighborhood Hits	91
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SPC25_MOUSE
NC score	0.197399 (rank : 850)	θ value	1.38821 (rank : 1068)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	206
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

DOC2B_HUMAN
NC score	0.197177 (rank : 851)	θ value	7.59969e-07 (rank : 217)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	88
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

K1C9_HUMAN
NC score	0.197058 (rank : 852)	θ value	θ > 10 (rank : 1787)
Query Neighborhood Hits	1371	Target Neighborhood Hits	526	Shared Neighborhood Hits	374
SwissProt Accessions	P35527, O00109, Q14665	Gene names	KRT9
Domain Architecture
Description	Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9).

NFH_HUMAN
NC score	0.196939 (rank : 853)	θ value	0.0252991 (rank : 684)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1242	Shared Neighborhood Hits	491
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BSN_HUMAN
NC score	0.196678 (rank : 854)	θ value	θ > 10 (rank : 1463)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1537	Shared Neighborhood Hits	431
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BAP29_MOUSE
NC score	0.196575 (rank : 855)	θ value	6.88961 (rank : 1283)
Query Neighborhood Hits	1371	Target Neighborhood Hits	285	Shared Neighborhood Hits	225
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

PERI_HUMAN
NC score	0.196551 (rank : 856)	θ value	θ > 10 (rank : 2013)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	380
SwissProt Accessions	P41219, Q8N577	Gene names	PRPH
Domain Architecture
Description	Peripherin.

PERI_MOUSE
NC score	0.196437 (rank : 857)	θ value	θ > 10 (rank : 2014)
Query Neighborhood Hits	1371	Target Neighborhood Hits	502	Shared Neighborhood Hits	376
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

PLCB3_HUMAN
NC score	0.196102 (rank : 858)	θ value	1.06291 (rank : 1026)
Query Neighborhood Hits	1371	Target Neighborhood Hits	445	Shared Neighborhood Hits	310
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

CCAR1_HUMAN
NC score	0.195851 (rank : 859)	θ value	θ > 10 (rank : 1472)
Query Neighborhood Hits	1371	Target Neighborhood Hits	444	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

BFSP2_MOUSE
NC score	0.195112 (rank : 860)	θ value	0.00665767 (rank : 589)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	303
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

DDEF2_MOUSE
NC score	0.195108 (rank : 861)	θ value	1.43324e-05 (rank : 312)
Query Neighborhood Hits	1371	Target Neighborhood Hits	625	Shared Neighborhood Hits	235
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

GPS2_HUMAN
NC score	0.194795 (rank : 862)	θ value	θ > 10 (rank : 1704)
Query Neighborhood Hits	1371	Target Neighborhood Hits	459	Shared Neighborhood Hits	228
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

LAMA4_HUMAN
NC score	0.194656 (rank : 863)	θ value	θ > 10 (rank : 1861)
Query Neighborhood Hits	1371	Target Neighborhood Hits	708	Shared Neighborhood Hits	351
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

PLVAP_MOUSE
NC score	0.194406 (rank : 864)	θ value	θ > 10 (rank : 2037)
Query Neighborhood Hits	1371	Target Neighborhood Hits	210	Shared Neighborhood Hits	178
SwissProt Accessions	Q91VC4, Q99JB1	Gene names	Plvap, Pv1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (MECA-32 antigen).

RP3A_MOUSE
NC score	0.194187 (rank : 865)	θ value	1.69304e-06 (rank : 241)
Query Neighborhood Hits	1371	Target Neighborhood Hits	510	Shared Neighborhood Hits	116
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

JIP4_MOUSE
NC score	0.194180 (rank : 866)	θ value	θ > 10 (rank : 1765)
Query Neighborhood Hits	1371	Target Neighborhood Hits	593	Shared Neighborhood Hits	359
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

RP3A_HUMAN
NC score	0.193975 (rank : 867)	θ value	1.43324e-05 (rank : 321)
Query Neighborhood Hits	1371	Target Neighborhood Hits	305	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DDEF2_HUMAN
NC score	0.193909 (rank : 868)	θ value	2.44474e-05 (rank : 340)
Query Neighborhood Hits	1371	Target Neighborhood Hits	599	Shared Neighborhood Hits	234
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

LAMB1_HUMAN
NC score	0.193816 (rank : 869)	θ value	1.06291 (rank : 1018)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1018	Shared Neighborhood Hits	430
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

DOC2A_MOUSE
NC score	0.192892 (rank : 870)	θ value	5.44631e-05 (rank : 370)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

N4BP3_MOUSE
NC score	0.192753 (rank : 871)	θ value	0.21417 (rank : 856)
Query Neighborhood Hits	1371	Target Neighborhood Hits	179	Shared Neighborhood Hits	144
SwissProt Accessions	Q8C7U1, Q3TDC7, Q7TNR2, Q922W0, Q99J06	Gene names	N4bp3
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

CEP72_MOUSE
NC score	0.192421 (rank : 872)	θ value	θ > 10 (rank : 1509)
Query Neighborhood Hits	1371	Target Neighborhood Hits	381	Shared Neighborhood Hits	236
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

DOC2A_HUMAN
NC score	0.192005 (rank : 873)	θ value	7.1131e-05 (rank : 381)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	89
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

NUCB1_HUMAN
NC score	0.191830 (rank : 874)	θ value	2.36792 (rank : 1149)
Query Neighborhood Hits	1371	Target Neighborhood Hits	359	Shared Neighborhood Hits	252
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

K0831_MOUSE
NC score	0.191473 (rank : 875)	θ value	0.21417 (rank : 845)
Query Neighborhood Hits	1371	Target Neighborhood Hits	277	Shared Neighborhood Hits	216
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

SURF6_MOUSE
NC score	0.191372 (rank : 876)	θ value	θ > 10 (rank : 2221)
Query Neighborhood Hits	1371	Target Neighborhood Hits	195	Shared Neighborhood Hits	156
SwissProt Accessions	P70279, Q8BPI4, Q8BRL7, Q8R0Q7	Gene names	Surf6, Surf-6
Domain Architecture
Description	Surfeit locus protein 6.

K1H2_HUMAN
NC score	0.191101 (rank : 877)	θ value	4.1701e-05 (rank : 357)
Query Neighborhood Hits	1371	Target Neighborhood Hits	492	Shared Neighborhood Hits	343
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

DOC2G_MOUSE
NC score	0.191076 (rank : 878)	θ value	0.000461057 (rank : 454)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

BRAP_MOUSE
NC score	0.190222 (rank : 879)	θ value	θ > 10 (rank : 1459)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	247
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

RNF8_MOUSE
NC score	0.189522 (rank : 880)	θ value	θ > 10 (rank : 2097)
Query Neighborhood Hits	1371	Target Neighborhood Hits	618	Shared Neighborhood Hits	316
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

ANR35_HUMAN
NC score	0.189257 (rank : 881)	θ value	1.06291 (rank : 1003)
Query Neighborhood Hits	1371	Target Neighborhood Hits	784	Shared Neighborhood Hits	377
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

LMO7_HUMAN
NC score	0.188353 (rank : 882)	θ value	8.99809 (rank : 1340)
Query Neighborhood Hits	1371	Target Neighborhood Hits	507	Shared Neighborhood Hits	247
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

BAZ1A_HUMAN
NC score	0.188122 (rank : 883)	θ value	5.27518 (rank : 1233)
Query Neighborhood Hits	1371	Target Neighborhood Hits	693	Shared Neighborhood Hits	397
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

K1C10_HUMAN
NC score	0.187971 (rank : 884)	θ value	θ > 10 (rank : 1773)
Query Neighborhood Hits	1371	Target Neighborhood Hits	526	Shared Neighborhood Hits	377
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

K2C4_MOUSE
NC score	0.187583 (rank : 885)	θ value	θ > 10 (rank : 1794)
Query Neighborhood Hits	1371	Target Neighborhood Hits	521	Shared Neighborhood Hits	389
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

PAWR_HUMAN
NC score	0.187553 (rank : 886)	θ value	1.06291 (rank : 1024)
Query Neighborhood Hits	1371	Target Neighborhood Hits	252	Shared Neighborhood Hits	160
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

CLUA1_HUMAN
NC score	0.187278 (rank : 887)	θ value	θ > 10 (rank : 1535)
Query Neighborhood Hits	1371	Target Neighborhood Hits	236	Shared Neighborhood Hits	190
SwissProt Accessions	Q96AJ1, O75138, Q65ZA3, Q9H8R4, Q9H8T1	Gene names	CLUAP1, KIAA0643
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

MYOF_HUMAN
NC score	0.187213 (rank : 888)	θ value	6.87365e-08 (rank : 172)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

TAF7_HUMAN
NC score	0.187172 (rank : 889)	θ value	θ > 10 (rank : 2248)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	186
SwissProt Accessions	Q15545, Q13036	Gene names	TAF7, TAF2F, TAFII55
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

SDS3_HUMAN
NC score	0.186953 (rank : 890)	θ value	θ > 10 (rank : 2120)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	196
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SLK_HUMAN
NC score	0.186843 (rank : 891)	θ value	0.00134147 (rank : 506)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1775	Shared Neighborhood Hits	656
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SPN90_HUMAN
NC score	0.186745 (rank : 892)	θ value	0.0330416 (rank : 701)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

K1C14_MOUSE
NC score	0.186719 (rank : 893)	θ value	θ > 10 (rank : 1779)
Query Neighborhood Hits	1371	Target Neighborhood Hits	501	Shared Neighborhood Hits	388
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

DESM_MOUSE
NC score	0.186506 (rank : 894)	θ value	θ > 10 (rank : 1580)
Query Neighborhood Hits	1371	Target Neighborhood Hits	498	Shared Neighborhood Hits	374
SwissProt Accessions	P31001	Gene names	Des
Domain Architecture
Description	Desmin.

CM007_HUMAN
NC score	0.186432 (rank : 895)	θ value	1.81305 (rank : 1083)
Query Neighborhood Hits	1371	Target Neighborhood Hits	422	Shared Neighborhood Hits	221
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

SHAN2_MOUSE
NC score	0.185946 (rank : 896)	θ value	0.0252991 (rank : 689)
Query Neighborhood Hits	1371	Target Neighborhood Hits	446	Shared Neighborhood Hits	154
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

NGAP_HUMAN
NC score	0.185444 (rank : 897)	θ value	8.99809 (rank : 1346)
Query Neighborhood Hits	1371	Target Neighborhood Hits	517	Shared Neighborhood Hits	351
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

DESM_HUMAN
NC score	0.185367 (rank : 898)	θ value	θ > 10 (rank : 1579)
Query Neighborhood Hits	1371	Target Neighborhood Hits	495	Shared Neighborhood Hits	370
SwissProt Accessions	P17661, Q15787, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80	Gene names	DES
Domain Architecture
Description	Desmin.

SLAP2_MOUSE
NC score	0.185254 (rank : 899)	θ value	0.62314 (rank : 973)
Query Neighborhood Hits	1371	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SPTN4_HUMAN
NC score	0.185086 (rank : 900)	θ value	θ > 10 (rank : 2182)
Query Neighborhood Hits	1371	Target Neighborhood Hits	570	Shared Neighborhood Hits	347
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

TAOK3_HUMAN
NC score	0.184951 (rank : 901)	θ value	3.77169e-06 (rank : 273)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1494	Shared Neighborhood Hits	553
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

DIAP1_HUMAN
NC score	0.184747 (rank : 902)	θ value	θ > 10 (rank : 1584)
Query Neighborhood Hits	1371	Target Neighborhood Hits	784	Shared Neighborhood Hits	378
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

K1H2_MOUSE
NC score	0.184312 (rank : 903)	θ value	0.000602161 (rank : 468)
Query Neighborhood Hits	1371	Target Neighborhood Hits	446	Shared Neighborhood Hits	335
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

TCGAP_MOUSE
NC score	0.184253 (rank : 904)	θ value	0.00175202 (rank : 528)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	156
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CCAR1_MOUSE
NC score	0.183249 (rank : 905)	θ value	θ > 10 (rank : 1473)
Query Neighborhood Hits	1371	Target Neighborhood Hits	414	Shared Neighborhood Hits	254
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

LAMC1_HUMAN
NC score	0.183066 (rank : 906)	θ value	θ > 10 (rank : 1867)
Query Neighborhood Hits	1371	Target Neighborhood Hits	922	Shared Neighborhood Hits	379
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SLK_MOUSE
NC score	0.182979 (rank : 907)	θ value	0.00134147 (rank : 507)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1798	Shared Neighborhood Hits	650
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

HOME3_MOUSE
NC score	0.182908 (rank : 908)	θ value	θ > 10 (rank : 1725)
Query Neighborhood Hits	1371	Target Neighborhood Hits	316	Shared Neighborhood Hits	235
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

EMIL2_HUMAN
NC score	0.182375 (rank : 909)	θ value	θ > 10 (rank : 1613)
Query Neighborhood Hits	1371	Target Neighborhood Hits	573	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

K2C6B_HUMAN
NC score	0.182277 (rank : 910)	θ value	5.27518 (rank : 1249)
Query Neighborhood Hits	1371	Target Neighborhood Hits	526	Shared Neighborhood Hits	395
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C6E_HUMAN
NC score	0.182222 (rank : 911)	θ value	5.27518 (rank : 1250)
Query Neighborhood Hits	1371	Target Neighborhood Hits	516	Shared Neighborhood Hits	387
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

SYCP3_HUMAN
NC score	0.182173 (rank : 912)	θ value	θ > 10 (rank : 2225)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	216
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

PCQAP_HUMAN
NC score	0.181881 (rank : 913)	θ value	θ > 10 (rank : 2008)
Query Neighborhood Hits	1371	Target Neighborhood Hits	549	Shared Neighborhood Hits	223
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

HOME3_HUMAN
NC score	0.181655 (rank : 914)	θ value	θ > 10 (rank : 1724)
Query Neighborhood Hits	1371	Target Neighborhood Hits	275	Shared Neighborhood Hits	211
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

SLAP2_HUMAN
NC score	0.181582 (rank : 915)	θ value	0.0961366 (rank : 791)
Query Neighborhood Hits	1371	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

A16L1_MOUSE
NC score	0.181533 (rank : 916)	θ value	0.279714 (rank : 870)
Query Neighborhood Hits	1371	Target Neighborhood Hits	776	Shared Neighborhood Hits	382
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

K2C1B_MOUSE
NC score	0.181434 (rank : 917)	θ value	0.00869519 (rank : 608)
Query Neighborhood Hits	1371	Target Neighborhood Hits	503	Shared Neighborhood Hits	369
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

K1C17_HUMAN
NC score	0.181385 (rank : 918)	θ value	θ > 10 (rank : 1782)
Query Neighborhood Hits	1371	Target Neighborhood Hits	463	Shared Neighborhood Hits	359
SwissProt Accessions	Q04695	Gene names	KRT17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1).

TJAP1_MOUSE
NC score	0.181012 (rank : 919)	θ value	0.47712 (rank : 952)
Query Neighborhood Hits	1371	Target Neighborhood Hits	295	Shared Neighborhood Hits	214
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

K22E_HUMAN
NC score	0.180935 (rank : 920)	θ value	1.06291 (rank : 1017)
Query Neighborhood Hits	1371	Target Neighborhood Hits	515	Shared Neighborhood Hits	356
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

K1HB_HUMAN
NC score	0.180688 (rank : 921)	θ value	0.47712 (rank : 942)
Query Neighborhood Hits	1371	Target Neighborhood Hits	470	Shared Neighborhood Hits	344
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

LAMA3_HUMAN
NC score	0.180556 (rank : 922)	θ value	θ > 10 (rank : 1859)
Query Neighborhood Hits	1371	Target Neighborhood Hits	760	Shared Neighborhood Hits	329
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

SFR12_MOUSE
NC score	0.180352 (rank : 923)	θ value	θ > 10 (rank : 2131)
Query Neighborhood Hits	1371	Target Neighborhood Hits	486	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SYT3_MOUSE
NC score	0.180001 (rank : 924)	θ value	1.43324e-05 (rank : 323)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

K1C18_HUMAN
NC score	0.179909 (rank : 925)	θ value	0.62314 (rank : 964)
Query Neighborhood Hits	1371	Target Neighborhood Hits	441	Shared Neighborhood Hits	335
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

TS101_HUMAN
NC score	0.179820 (rank : 926)	θ value	θ > 10 (rank : 2296)
Query Neighborhood Hits	1371	Target Neighborhood Hits	359	Shared Neighborhood Hits	243
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

SYT3_HUMAN
NC score	0.179582 (rank : 927)	θ value	1.87187e-05 (rank : 337)
Query Neighborhood Hits	1371	Target Neighborhood Hits	145	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT7_HUMAN
NC score	0.179383 (rank : 928)	θ value	0.000461057 (rank : 461)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

CCD37_HUMAN
NC score	0.178990 (rank : 929)	θ value	0.62314 (rank : 959)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	203
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

SYT5_HUMAN
NC score	0.178900 (rank : 930)	θ value	2.21117e-06 (rank : 253)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	85
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

ES8L2_HUMAN
NC score	0.178885 (rank : 931)	θ value	0.0961366 (rank : 781)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	143
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

APOA1_MOUSE
NC score	0.178678 (rank : 932)	θ value	θ > 10 (rank : 1416)
Query Neighborhood Hits	1371	Target Neighborhood Hits	210	Shared Neighborhood Hits	164
SwissProt Accessions	Q00623	Gene names	Apoa1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I).

K1C14_HUMAN
NC score	0.178608 (rank : 933)	θ value	θ > 10 (rank : 1778)
Query Neighborhood Hits	1371	Target Neighborhood Hits	491	Shared Neighborhood Hits	384
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

SDS3_MOUSE
NC score	0.178339 (rank : 934)	θ value	θ > 10 (rank : 2121)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	186
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

BSN_MOUSE
NC score	0.178283 (rank : 935)	θ value	θ > 10 (rank : 1464)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2057	Shared Neighborhood Hits	477
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

K1C20_HUMAN
NC score	0.177542 (rank : 936)	θ value	1.06291 (rank : 1016)
Query Neighborhood Hits	1371	Target Neighborhood Hits	468	Shared Neighborhood Hits	354
SwissProt Accessions	P35900	Gene names	KRT20
Domain Architecture
Description	Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT).

SYT7_MOUSE
NC score	0.177369 (rank : 937)	θ value	0.000121331 (rank : 406)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

NUP88_MOUSE
NC score	0.177351 (rank : 938)	θ value	2.36792 (rank : 1150)
Query Neighborhood Hits	1371	Target Neighborhood Hits	239	Shared Neighborhood Hits	198
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

K0528_MOUSE
NC score	0.176906 (rank : 939)	θ value	0.000461057 (rank : 458)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_HUMAN
NC score	0.176861 (rank : 940)	θ value	0.000461057 (rank : 457)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K2C5_HUMAN
NC score	0.176639 (rank : 941)	θ value	θ > 10 (rank : 1795)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	383
SwissProt Accessions	P13647, Q6PI71, Q6UBJ0, Q8TA91	Gene names	KRT5
Domain Architecture
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin).

ZN318_MOUSE
NC score	0.176336 (rank : 942)	θ value	0.21417 (rank : 868)
Query Neighborhood Hits	1371	Target Neighborhood Hits	642	Shared Neighborhood Hits	294
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

K1C17_MOUSE
NC score	0.176294 (rank : 943)	θ value	θ > 10 (rank : 1783)
Query Neighborhood Hits	1371	Target Neighborhood Hits	456	Shared Neighborhood Hits	346
SwissProt Accessions	Q9QWL7, Q61783	Gene names	Krt17, Krt1-17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17).

STX4_MOUSE
NC score	0.176221 (rank : 944)	θ value	θ > 10 (rank : 2213)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	242
SwissProt Accessions	P70452	Gene names	Stx4, Stx4a
Domain Architecture
Description	Syntaxin-4.

SYT1_HUMAN
NC score	0.176052 (rank : 945)	θ value	4.92598e-06 (rank : 281)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	90
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

MRCKG_MOUSE
NC score	0.176047 (rank : 946)	θ value	4.03905 (rank : 1215)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1466	Shared Neighborhood Hits	547
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

SYT1_MOUSE
NC score	0.176039 (rank : 947)	θ value	4.92598e-06 (rank : 282)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	90
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

MYOC_HUMAN
NC score	0.175727 (rank : 948)	θ value	θ > 10 (rank : 1948)
Query Neighborhood Hits	1371	Target Neighborhood Hits	489	Shared Neighborhood Hits	345
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

TAOK3_MOUSE
NC score	0.175494 (rank : 949)	θ value	1.09739e-05 (rank : 306)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1458	Shared Neighborhood Hits	539
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

K2C6B_MOUSE
NC score	0.175195 (rank : 950)	θ value	θ > 10 (rank : 1798)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	378
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

K2C6C_HUMAN
NC score	0.175175 (rank : 951)	θ value	θ > 10 (rank : 1799)
Query Neighborhood Hits	1371	Target Neighborhood Hits	503	Shared Neighborhood Hits	379
SwissProt Accessions	P48666	Gene names	KRT6C
Domain Architecture
Description	Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin).

ES8L2_MOUSE
NC score	0.175172 (rank : 952)	θ value	0.21417 (rank : 842)
Query Neighborhood Hits	1371	Target Neighborhood Hits	169	Shared Neighborhood Hits	138
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

K2C6A_HUMAN
NC score	0.175024 (rank : 953)	θ value	θ > 10 (rank : 1796)
Query Neighborhood Hits	1371	Target Neighborhood Hits	505	Shared Neighborhood Hits	382
SwissProt Accessions	P02538, Q6NT67, Q96CL4	Gene names	KRT6A, K6A
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin).

AAT1_HUMAN
NC score	0.174970 (rank : 954)	θ value	5.27518 (rank : 1230)
Query Neighborhood Hits	1371	Target Neighborhood Hits	199	Shared Neighborhood Hits	161
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

GO45_HUMAN
NC score	0.174650 (rank : 955)	θ value	θ > 10 (rank : 1700)
Query Neighborhood Hits	1371	Target Neighborhood Hits	189	Shared Neighborhood Hits	160
SwissProt Accessions	Q9H2G9, O15298, Q5T531, Q9GZX4	Gene names	BLZF1, JEM1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor).

MAP1B_HUMAN
NC score	0.174524 (rank : 956)	θ value	1.38821 (rank : 1057)
Query Neighborhood Hits	1371	Target Neighborhood Hits	903	Shared Neighborhood Hits	308
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SYT2_MOUSE
NC score	0.174476 (rank : 957)	θ value	2.88788e-06 (rank : 265)
Query Neighborhood Hits	1371	Target Neighborhood Hits	143	Shared Neighborhood Hits	86
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.174414 (rank : 958)	θ value	2.88788e-06 (rank : 264)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

TAF7_MOUSE
NC score	0.174304 (rank : 959)	θ value	θ > 10 (rank : 2249)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	183
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

KI20A_HUMAN
NC score	0.174248 (rank : 960)	θ value	θ > 10 (rank : 1807)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	237
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

UN13A_HUMAN
NC score	0.174237 (rank : 961)	θ value	0.000158464 (rank : 416)
Query Neighborhood Hits	1371	Target Neighborhood Hits	285	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

TNNT1_MOUSE
NC score	0.173458 (rank : 962)	θ value	0.47712 (rank : 954)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	185
SwissProt Accessions	O88346, O88795, Q9QUP7	Gene names	Tnnt1
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

K2C5_MOUSE
NC score	0.173434 (rank : 963)	θ value	1.38821 (rank : 1054)
Query Neighborhood Hits	1371	Target Neighborhood Hits	505	Shared Neighborhood Hits	375
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

SYT5_MOUSE
NC score	0.173188 (rank : 964)	θ value	7.1131e-05 (rank : 387)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

LAMA2_HUMAN
NC score	0.173098 (rank : 965)	θ value	θ > 10 (rank : 1858)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1092	Shared Neighborhood Hits	399
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

K2C4_HUMAN
NC score	0.173063 (rank : 966)	θ value	2.36792 (rank : 1142)
Query Neighborhood Hits	1371	Target Neighborhood Hits	471	Shared Neighborhood Hits	344
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

DMN_HUMAN
NC score	0.172927 (rank : 967)	θ value	0.0113563 (rank : 621)
Query Neighborhood Hits	1371	Target Neighborhood Hits	690	Shared Neighborhood Hits	354
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

K1H1_MOUSE
NC score	0.172775 (rank : 968)	θ value	θ > 10 (rank : 1789)
Query Neighborhood Hits	1371	Target Neighborhood Hits	450	Shared Neighborhood Hits	342
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

MRCKG_HUMAN
NC score	0.172587 (rank : 969)	θ value	0.21417 (rank : 854)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1519	Shared Neighborhood Hits	542
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

K2C1B_HUMAN
NC score	0.172458 (rank : 970)	θ value	3.0926 (rank : 1177)
Query Neighborhood Hits	1371	Target Neighborhood Hits	542	Shared Neighborhood Hits	376
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

K1C15_MOUSE
NC score	0.172142 (rank : 971)	θ value	0.21417 (rank : 846)
Query Neighborhood Hits	1371	Target Neighborhood Hits	429	Shared Neighborhood Hits	325
SwissProt Accessions	Q61414, Q6PEQ0	Gene names	Krt15, Krt1-15
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

SPTN2_HUMAN
NC score	0.172092 (rank : 972)	θ value	θ > 10 (rank : 2181)
Query Neighborhood Hits	1371	Target Neighborhood Hits	535	Shared Neighborhood Hits	334
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

TXD11_HUMAN
NC score	0.172030 (rank : 973)	θ value	θ > 10 (rank : 2301)
Query Neighborhood Hits	1371	Target Neighborhood Hits	402	Shared Neighborhood Hits	245
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

STX12_MOUSE
NC score	0.171855 (rank : 974)	θ value	θ > 10 (rank : 2204)
Query Neighborhood Hits	1371	Target Neighborhood Hits	283	Shared Neighborhood Hits	220
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

KLC1_HUMAN
NC score	0.171736 (rank : 975)	θ value	θ > 10 (rank : 1830)
Query Neighborhood Hits	1371	Target Neighborhood Hits	471	Shared Neighborhood Hits	328
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

AMPH_HUMAN
NC score	0.171694 (rank : 976)	θ value	0.0961366 (rank : 773)
Query Neighborhood Hits	1371	Target Neighborhood Hits	455	Shared Neighborhood Hits	192
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

TEKT2_MOUSE
NC score	0.171346 (rank : 977)	θ value	4.03905 (rank : 1226)
Query Neighborhood Hits	1371	Target Neighborhood Hits	199	Shared Neighborhood Hits	161
SwissProt Accessions	Q922G7, Q9WVR0	Gene names	Tekt2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t).

TMCO3_HUMAN
NC score	0.171256 (rank : 978)	θ value	0.0330416 (rank : 704)
Query Neighborhood Hits	1371	Target Neighborhood Hits	238	Shared Neighborhood Hits	192
SwissProt Accessions	Q6UWJ1, Q5JSB1, Q6NUN1, Q8NG29, Q8TCI6, Q96EA6, Q9NWT2	Gene names	TMCO3, C13orf11
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domain-containing protein 3 precursor (Putative LAG1-interacting protein).

RFIP2_HUMAN
NC score	0.170735 (rank : 979)	θ value	0.00298849 (rank : 559)
Query Neighborhood Hits	1371	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

M4K4_HUMAN
NC score	0.170572 (rank : 980)	θ value	0.000786445 (rank : 486)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1589	Shared Neighborhood Hits	601
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

AMRP_MOUSE
NC score	0.170363 (rank : 981)	θ value	0.62314 (rank : 958)
Query Neighborhood Hits	1371	Target Neighborhood Hits	173	Shared Neighborhood Hits	146
SwissProt Accessions	P55302	Gene names	Lrpap1
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin-binding protein 44) (HBP-44).

RHG25_HUMAN
NC score	0.170261 (rank : 982)	θ value	5.27518 (rank : 1262)
Query Neighborhood Hits	1371	Target Neighborhood Hits	550	Shared Neighborhood Hits	318
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

OTOF_MOUSE
NC score	0.170073 (rank : 983)	θ value	1.43324e-05 (rank : 320)
Query Neighborhood Hits	1371	Target Neighborhood Hits	196	Shared Neighborhood Hits	112
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

ES8L1_MOUSE
NC score	0.169675 (rank : 984)	θ value	0.00390308 (rank : 566)
Query Neighborhood Hits	1371	Target Neighborhood Hits	143	Shared Neighborhood Hits	98
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

PCQAP_MOUSE
NC score	0.169620 (rank : 985)	θ value	θ > 10 (rank : 2009)
Query Neighborhood Hits	1371	Target Neighborhood Hits	506	Shared Neighborhood Hits	193
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

K1C10_MOUSE
NC score	0.169478 (rank : 986)	θ value	0.47712 (rank : 941)
Query Neighborhood Hits	1371	Target Neighborhood Hits	466	Shared Neighborhood Hits	335
SwissProt Accessions	P02535, P08731, Q8BUX3, Q8BV09, Q8BVU3, Q9CXH6, Q9JKB4	Gene names	Krt10, Krt1-10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) (56 kDa cytokeratin) (Keratin, type I cytoskeletal 59 kDa).

WDR60_MOUSE
NC score	0.169265 (rank : 987)	θ value	θ > 10 (rank : 2327)
Query Neighborhood Hits	1371	Target Neighborhood Hits	344	Shared Neighborhood Hits	183
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ATD3B_HUMAN
NC score	0.168967 (rank : 988)	θ value	θ > 10 (rank : 1431)
Query Neighborhood Hits	1371	Target Neighborhood Hits	340	Shared Neighborhood Hits	245
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

STS2_HUMAN
NC score	0.168949 (rank : 989)	θ value	0.0148317 (rank : 652)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	87
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

OTOF_HUMAN
NC score	0.168780 (rank : 990)	θ value	1.43324e-05 (rank : 319)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

K2C6A_MOUSE
NC score	0.168599 (rank : 991)	θ value	θ > 10 (rank : 1797)
Query Neighborhood Hits	1371	Target Neighborhood Hits	481	Shared Neighborhood Hits	357
SwissProt Accessions	P50446, Q9Z332	Gene names	Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin) (Keratin-6 alpha) (mK6-alpha).

SMCE1_MOUSE
NC score	0.168471 (rank : 992)	θ value	0.279714 (rank : 890)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	186
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SYT10_MOUSE
NC score	0.168439 (rank : 993)	θ value	0.00175202 (rank : 526)
Query Neighborhood Hits	1371	Target Neighborhood Hits	133	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

APOA1_HUMAN
NC score	0.167993 (rank : 994)	θ value	2.36792 (rank : 1120)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	201
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

RASL1_HUMAN
NC score	0.167681 (rank : 995)	θ value	0.000270298 (rank : 434)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	95
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

K1C16_MOUSE
NC score	0.167413 (rank : 996)	θ value	0.0961366 (rank : 786)
Query Neighborhood Hits	1371	Target Neighborhood Hits	444	Shared Neighborhood Hits	338
SwissProt Accessions	Q9Z2K1	Gene names	Krt16, Krt1-16
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

DYSF_HUMAN
NC score	0.166742 (rank : 997)	θ value	1.87187e-05 (rank : 328)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	97
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

MPP10_HUMAN
NC score	0.166670 (rank : 998)	θ value	θ > 10 (rank : 1923)
Query Neighborhood Hits	1371	Target Neighborhood Hits	306	Shared Neighborhood Hits	198
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

NASP_HUMAN
NC score	0.166535 (rank : 999)	θ value	θ > 10 (rank : 1960)
Query Neighborhood Hits	1371	Target Neighborhood Hits	709	Shared Neighborhood Hits	267
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

AINX_HUMAN
NC score	0.166488 (rank : 1000)	θ value	θ > 10 (rank : 1392)
Query Neighborhood Hits	1371	Target Neighborhood Hits	442	Shared Neighborhood Hits	335
SwissProt Accessions	Q16352, Q9BRC5	Gene names	INA
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

M4K4_MOUSE
NC score	0.166408 (rank : 1001)	θ value	0.000786445 (rank : 487)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1560	Shared Neighborhood Hits	578
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

SHAN1_HUMAN
NC score	0.166090 (rank : 1002)	θ value	0.00175202 (rank : 523)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1041	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SEC20_HUMAN
NC score	0.165909 (rank : 1003)	θ value	θ > 10 (rank : 2122)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	169
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

UN13B_MOUSE
NC score	0.165551 (rank : 1004)	θ value	0.00298849 (rank : 562)
Query Neighborhood Hits	1371	Target Neighborhood Hits	210	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

TCGAP_HUMAN
NC score	0.165527 (rank : 1005)	θ value	0.00175202 (rank : 527)
Query Neighborhood Hits	1371	Target Neighborhood Hits	872	Shared Neighborhood Hits	187
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

KI20A_MOUSE
NC score	0.165491 (rank : 1006)	θ value	θ > 10 (rank : 1808)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	232
SwissProt Accessions	P97329, Q542M4	Gene names	Kif20a, Rab6kifl
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (Kinesin-like protein 174).

N4BP3_HUMAN
NC score	0.165355 (rank : 1007)	θ value	0.21417 (rank : 855)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	120
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

GAS7_HUMAN
NC score	0.165329 (rank : 1008)	θ value	θ > 10 (rank : 1685)
Query Neighborhood Hits	1371	Target Neighborhood Hits	258	Shared Neighborhood Hits	185
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

SYT6_HUMAN
NC score	0.165239 (rank : 1009)	θ value	0.00390308 (rank : 571)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	83
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

AINX_MOUSE
NC score	0.165133 (rank : 1010)	θ value	θ > 10 (rank : 1393)
Query Neighborhood Hits	1371	Target Neighborhood Hits	448	Shared Neighborhood Hits	337
SwissProt Accessions	P46660, Q61958, Q8VCW5	Gene names	Ina
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

PKHA5_HUMAN
NC score	0.165068 (rank : 1011)	θ value	θ > 10 (rank : 2021)
Query Neighborhood Hits	1371	Target Neighborhood Hits	455	Shared Neighborhood Hits	225
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

DUET_HUMAN
NC score	0.164869 (rank : 1012)	θ value	3.52202e-12 (rank : 80)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1220	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ARI4A_HUMAN
NC score	0.164682 (rank : 1013)	θ value	0.0563607 (rank : 720)
Query Neighborhood Hits	1371	Target Neighborhood Hits	434	Shared Neighborhood Hits	204
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

K2C1_MOUSE
NC score	0.164590 (rank : 1014)	θ value	0.813845 (rank : 982)
Query Neighborhood Hits	1371	Target Neighborhood Hits	477	Shared Neighborhood Hits	351
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

SYT6_MOUSE
NC score	0.164558 (rank : 1015)	θ value	0.0113563 (rank : 633)
Query Neighborhood Hits	1371	Target Neighborhood Hits	132	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

K0586_HUMAN
NC score	0.164380 (rank : 1016)	θ value	8.99809 (rank : 1336)
Query Neighborhood Hits	1371	Target Neighborhood Hits	311	Shared Neighborhood Hits	172
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

SYT9_HUMAN
NC score	0.164317 (rank : 1017)	θ value	0.00298849 (rank : 560)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	89
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

K1H1_HUMAN
NC score	0.163769 (rank : 1018)	θ value	θ > 10 (rank : 1788)
Query Neighborhood Hits	1371	Target Neighborhood Hits	433	Shared Neighborhood Hits	315
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

SYT9_MOUSE
NC score	0.163513 (rank : 1019)	θ value	0.00509761 (rank : 587)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

STX4_HUMAN
NC score	0.163217 (rank : 1020)	θ value	θ > 10 (rank : 2212)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	210
SwissProt Accessions	Q12846, Q15525	Gene names	STX4, STX4A
Domain Architecture
Description	Syntaxin-4 (NY-REN-31 antigen).

PLCB3_MOUSE
NC score	0.163177 (rank : 1021)	θ value	θ > 10 (rank : 2034)
Query Neighborhood Hits	1371	Target Neighborhood Hits	344	Shared Neighborhood Hits	251
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

SHLB1_HUMAN
NC score	0.162917 (rank : 1022)	θ value	1.06291 (rank : 1031)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SYT10_HUMAN
NC score	0.162649 (rank : 1023)	θ value	0.0252991 (rank : 691)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	84
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

K1C16_HUMAN
NC score	0.162145 (rank : 1024)	θ value	θ > 10 (rank : 1781)
Query Neighborhood Hits	1371	Target Neighborhood Hits	440	Shared Neighborhood Hits	337
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

K2C6G_MOUSE
NC score	0.161718 (rank : 1025)	θ value	θ > 10 (rank : 1800)
Query Neighborhood Hits	1371	Target Neighborhood Hits	452	Shared Neighborhood Hits	325
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

FYN_MOUSE
NC score	0.161678 (rank : 1026)	θ value	2.79066e-09 (rank : 128)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1073	Shared Neighborhood Hits	267
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

CCD50_HUMAN
NC score	0.161658 (rank : 1027)	θ value	θ > 10 (rank : 1481)
Query Neighborhood Hits	1371	Target Neighborhood Hits	237	Shared Neighborhood Hits	181
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

GBP2_HUMAN
NC score	0.161600 (rank : 1028)	θ value	θ > 10 (rank : 1689)
Query Neighborhood Hits	1371	Target Neighborhood Hits	349	Shared Neighborhood Hits	268
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

DYSF_MOUSE
NC score	0.161424 (rank : 1029)	θ value	7.1131e-05 (rank : 382)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DZIP3_HUMAN
NC score	0.161239 (rank : 1030)	θ value	θ > 10 (rank : 1606)
Query Neighborhood Hits	1371	Target Neighborhood Hits	399	Shared Neighborhood Hits	227
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

SDPR_HUMAN
NC score	0.160912 (rank : 1031)	θ value	0.0736092 (rank : 765)
Query Neighborhood Hits	1371	Target Neighborhood Hits	337	Shared Neighborhood Hits	193
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

FGR_HUMAN
NC score	0.160746 (rank : 1032)	θ value	2.79066e-09 (rank : 126)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1067	Shared Neighborhood Hits	258
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ATRX_HUMAN
NC score	0.160666 (rank : 1033)	θ value	0.163984 (rank : 821)
Query Neighborhood Hits	1371	Target Neighborhood Hits	842	Shared Neighborhood Hits	354
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CHCH3_MOUSE
NC score	0.160410 (rank : 1034)	θ value	6.88961 (rank : 1288)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	202
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

SHLB1_MOUSE
NC score	0.160339 (rank : 1035)	θ value	1.38821 (rank : 1067)
Query Neighborhood Hits	1371	Target Neighborhood Hits	101	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

CCD37_MOUSE
NC score	0.160198 (rank : 1036)	θ value	θ > 10 (rank : 1478)
Query Neighborhood Hits	1371	Target Neighborhood Hits	199	Shared Neighborhood Hits	167
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

ABTAP_HUMAN
NC score	0.160189 (rank : 1037)	θ value	θ > 10 (rank : 1380)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	174
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

FYN_HUMAN
NC score	0.160042 (rank : 1038)	θ value	2.79066e-09 (rank : 127)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1078	Shared Neighborhood Hits	268
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

ES8L1_HUMAN
NC score	0.159915 (rank : 1039)	θ value	1.06291 (rank : 1013)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	113
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

PA24D_MOUSE
NC score	0.159625 (rank : 1040)	θ value	1.87187e-05 (rank : 333)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

TS101_MOUSE
NC score	0.159480 (rank : 1041)	θ value	θ > 10 (rank : 2297)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	218
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

SSNA1_MOUSE
NC score	0.159025 (rank : 1042)	θ value	θ > 10 (rank : 2192)
Query Neighborhood Hits	1371	Target Neighborhood Hits	182	Shared Neighborhood Hits	149
SwissProt Accessions	Q9JJ94	Gene names	Ssna1
Domain Architecture	No domain graphic available
Description	Sjoegren syndrome nuclear autoantigen 1 homolog.

UN13B_HUMAN
NC score	0.158999 (rank : 1043)	θ value	0.0148317 (rank : 654)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	120
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ATAD3_MOUSE
NC score	0.158990 (rank : 1044)	θ value	θ > 10 (rank : 1429)
Query Neighborhood Hits	1371	Target Neighborhood Hits	326	Shared Neighborhood Hits	228
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

SNPH_HUMAN
NC score	0.158734 (rank : 1045)	θ value	θ > 10 (rank : 2165)
Query Neighborhood Hits	1371	Target Neighborhood Hits	236	Shared Neighborhood Hits	166
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

SPN90_MOUSE
NC score	0.158719 (rank : 1046)	θ value	0.21417 (rank : 865)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

UBXD2_HUMAN
NC score	0.158545 (rank : 1047)	θ value	0.0563607 (rank : 741)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	169
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

EPS8_MOUSE
NC score	0.158425 (rank : 1048)	θ value	1.81305 (rank : 1089)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	136
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

RAB3I_HUMAN
NC score	0.158377 (rank : 1049)	θ value	θ > 10 (rank : 2055)
Query Neighborhood Hits	1371	Target Neighborhood Hits	270	Shared Neighborhood Hits	221
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

K0831_HUMAN
NC score	0.158321 (rank : 1050)	θ value	0.813845 (rank : 981)
Query Neighborhood Hits	1371	Target Neighborhood Hits	203	Shared Neighborhood Hits	164
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

POT15_HUMAN
NC score	0.158321 (rank : 1051)	θ value	0.000121331 (rank : 400)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	388
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

LRC27_HUMAN
NC score	0.158087 (rank : 1052)	θ value	1.81305 (rank : 1099)
Query Neighborhood Hits	1371	Target Neighborhood Hits	710	Shared Neighborhood Hits	305
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

TMCO3_MOUSE
NC score	0.157772 (rank : 1053)	θ value	θ > 10 (rank : 2279)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	194
SwissProt Accessions	Q8BH01, Q3UFX1, Q7TMT5, Q8BGL4, Q8R303	Gene names	Tmco3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domain-containing protein 3 precursor.

ANR21_HUMAN
NC score	0.157754 (rank : 1054)	θ value	0.000461057 (rank : 451)
Query Neighborhood Hits	1371	Target Neighborhood Hits	864	Shared Neighborhood Hits	379
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

SLAP1_HUMAN
NC score	0.157692 (rank : 1055)	θ value	θ > 10 (rank : 2155)
Query Neighborhood Hits	1371	Target Neighborhood Hits	113	Shared Neighborhood Hits	64
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

UN13D_HUMAN
NC score	0.157595 (rank : 1056)	θ value	0.0736092 (rank : 769)
Query Neighborhood Hits	1371	Target Neighborhood Hits	117	Shared Neighborhood Hits	85
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

CS029_HUMAN
NC score	0.157532 (rank : 1057)	θ value	6.88961 (rank : 1294)
Query Neighborhood Hits	1371	Target Neighborhood Hits	329	Shared Neighborhood Hits	231
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

YES_MOUSE
NC score	0.157516 (rank : 1058)	θ value	1.99992e-07 (rank : 187)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1052	Shared Neighborhood Hits	262
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

RASL1_MOUSE
NC score	0.157459 (rank : 1059)	θ value	0.0148317 (rank : 650)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

AMPH_MOUSE
NC score	0.157284 (rank : 1060)	θ value	0.279714 (rank : 872)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	154
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

BFSP2_HUMAN
NC score	0.156897 (rank : 1061)	θ value	0.125558 (rank : 805)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	264
SwissProt Accessions	Q13515, Q9HBW5	Gene names	BFSP2
Domain Architecture
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein) (CP 47) (CP47) (Lens intermediate filament-like light) (LIFL-L).

GAS7_MOUSE
NC score	0.156353 (rank : 1062)	θ value	θ > 10 (rank : 1686)
Query Neighborhood Hits	1371	Target Neighborhood Hits	259	Shared Neighborhood Hits	180
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

M3KL4_HUMAN
NC score	0.156312 (rank : 1063)	θ value	1.17247e-07 (rank : 178)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1087	Shared Neighborhood Hits	323
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

SLAP1_MOUSE
NC score	0.156198 (rank : 1064)	θ value	θ > 10 (rank : 2156)
Query Neighborhood Hits	1371	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SNX9_HUMAN
NC score	0.156157 (rank : 1065)	θ value	8.99809 (rank : 1362)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

GBP1_HUMAN
NC score	0.156141 (rank : 1066)	θ value	θ > 10 (rank : 1687)
Query Neighborhood Hits	1371	Target Neighborhood Hits	339	Shared Neighborhood Hits	264
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

YES_HUMAN
NC score	0.156116 (rank : 1067)	θ value	4.45536e-07 (rank : 207)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1059	Shared Neighborhood Hits	261
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

DZIP3_MOUSE
NC score	0.156070 (rank : 1068)	θ value	θ > 10 (rank : 1607)
Query Neighborhood Hits	1371	Target Neighborhood Hits	414	Shared Neighborhood Hits	223
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DAAM1_MOUSE
NC score	0.155961 (rank : 1069)	θ value	0.365318 (rank : 905)
Query Neighborhood Hits	1371	Target Neighborhood Hits	443	Shared Neighborhood Hits	284
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

ABTAP_MOUSE
NC score	0.155906 (rank : 1070)	θ value	θ > 10 (rank : 1381)
Query Neighborhood Hits	1371	Target Neighborhood Hits	381	Shared Neighborhood Hits	194
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

SRC_HUMAN
NC score	0.155773 (rank : 1071)	θ value	1.06045e-08 (rank : 138)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1058	Shared Neighborhood Hits	265
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

K1H6_HUMAN
NC score	0.155725 (rank : 1072)	θ value	θ > 10 (rank : 1791)
Query Neighborhood Hits	1371	Target Neighborhood Hits	408	Shared Neighborhood Hits	320
SwissProt Accessions	O76013	Gene names	KRTHA6, HHA6, HKA6
Domain Architecture
Description	Keratin, type I cuticular Ha6 (Hair keratin, type I Ha6).

LAMC1_MOUSE
NC score	0.154756 (rank : 1073)	θ value	1.81305 (rank : 1096)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	343
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

K1C13_MOUSE
NC score	0.154711 (rank : 1074)	θ value	θ > 10 (rank : 1777)
Query Neighborhood Hits	1371	Target Neighborhood Hits	410	Shared Neighborhood Hits	321
SwissProt Accessions	P08730, Q3V176, Q6PAI1	Gene names	Krt13, Krt1-13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13) (47 kDa cytokeratin).

TAOK2_MOUSE
NC score	0.154529 (rank : 1075)	θ value	0.00134147 (rank : 508)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1373	Shared Neighborhood Hits	478
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

FGR_MOUSE
NC score	0.154384 (rank : 1076)	θ value	2.61198e-07 (rank : 188)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1069	Shared Neighborhood Hits	260
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

LAMB1_MOUSE
NC score	0.154117 (rank : 1077)	θ value	1.38821 (rank : 1055)
Query Neighborhood Hits	1371	Target Neighborhood Hits	919	Shared Neighborhood Hits	383
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

REN3A_HUMAN
NC score	0.153973 (rank : 1078)	θ value	θ > 10 (rank : 2070)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

NFH_MOUSE
NC score	0.153250 (rank : 1079)	θ value	1.06291 (rank : 1022)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2247	Shared Neighborhood Hits	544
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SSNA1_HUMAN
NC score	0.153047 (rank : 1080)	θ value	θ > 10 (rank : 2191)
Query Neighborhood Hits	1371	Target Neighborhood Hits	175	Shared Neighborhood Hits	141
SwissProt Accessions	O43805, Q6FG70, Q9BVW8	Gene names	SSNA1, NA14
Domain Architecture
Description	Sjoegren syndrome nuclear autoantigen 1 (Nuclear autoantigen of 14 kDa).

TNNT1_HUMAN
NC score	0.152736 (rank : 1081)	θ value	0.47712 (rank : 953)
Query Neighborhood Hits	1371	Target Neighborhood Hits	211	Shared Neighborhood Hits	164
SwissProt Accessions	P13805, O95472, Q16061	Gene names	TNNT1, TNT
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

DISC1_HUMAN
NC score	0.152554 (rank : 1082)	θ value	θ > 10 (rank : 1586)
Query Neighborhood Hits	1371	Target Neighborhood Hits	199	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NRI5, O75045, Q5VT44, Q5VT45, Q8IXJ0, Q8IXJ1, Q9BX19, Q9NRI3, Q9NRI4	Gene names	DISC1, KIAA0457
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 protein.

TTC14_HUMAN
NC score	0.152540 (rank : 1083)	θ value	1.38821 (rank : 1073)
Query Neighborhood Hits	1371	Target Neighborhood Hits	274	Shared Neighborhood Hits	142
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

MPP8_HUMAN
NC score	0.152533 (rank : 1084)	θ value	0.62314 (rank : 968)
Query Neighborhood Hits	1371	Target Neighborhood Hits	948	Shared Neighborhood Hits	330
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

A16L1_HUMAN
NC score	0.152477 (rank : 1085)	θ value	0.279714 (rank : 869)
Query Neighborhood Hits	1371	Target Neighborhood Hits	664	Shared Neighborhood Hits	316
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

EPS8_HUMAN
NC score	0.152344 (rank : 1086)	θ value	1.81305 (rank : 1088)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	116
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

SYT4_HUMAN
NC score	0.151924 (rank : 1087)	θ value	0.47712 (rank : 951)
Query Neighborhood Hits	1371	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

NOL10_HUMAN
NC score	0.151652 (rank : 1088)	θ value	0.365318 (rank : 917)
Query Neighborhood Hits	1371	Target Neighborhood Hits	254	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

K1H7_HUMAN
NC score	0.151517 (rank : 1089)	θ value	0.00175202 (rank : 515)
Query Neighborhood Hits	1371	Target Neighborhood Hits	369	Shared Neighborhood Hits	290
SwissProt Accessions	O76014	Gene names	KRTHA7, HHA7, HKA7
Domain Architecture
Description	Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7).

K1C18_MOUSE
NC score	0.151066 (rank : 1090)	θ value	4.03905 (rank : 1208)
Query Neighborhood Hits	1371	Target Neighborhood Hits	386	Shared Neighborhood Hits	296
SwissProt Accessions	P05784, Q61766	Gene names	Krt18, Kerd, Krt1-18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18) (Cytokeratin endo B) (Keratin D).

RILP_HUMAN
NC score	0.151013 (rank : 1091)	θ value	θ > 10 (rank : 2081)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	160
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

TBCD2_HUMAN
NC score	0.150872 (rank : 1092)	θ value	θ > 10 (rank : 2255)
Query Neighborhood Hits	1371	Target Neighborhood Hits	419	Shared Neighborhood Hits	226
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

SYTL4_HUMAN
NC score	0.150225 (rank : 1093)	θ value	0.00665767 (rank : 602)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	81
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

K1H8_HUMAN
NC score	0.150221 (rank : 1094)	θ value	0.125558 (rank : 811)
Query Neighborhood Hits	1371	Target Neighborhood Hits	394	Shared Neighborhood Hits	295
SwissProt Accessions	O76015	Gene names	KRTHA8, HHA8, HKA8
Domain Architecture
Description	Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8).

BAZ1B_HUMAN
NC score	0.150179 (rank : 1095)	θ value	0.0961366 (rank : 774)
Query Neighborhood Hits	1371	Target Neighborhood Hits	701	Shared Neighborhood Hits	346
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

SHLB2_MOUSE
NC score	0.150118 (rank : 1096)	θ value	0.21417 (rank : 863)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

NOP14_MOUSE
NC score	0.149410 (rank : 1097)	θ value	θ > 10 (rank : 1978)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	188
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

SHLB2_HUMAN
NC score	0.149259 (rank : 1098)	θ value	0.21417 (rank : 862)
Query Neighborhood Hits	1371	Target Neighborhood Hits	86	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

DAAM1_HUMAN
NC score	0.149045 (rank : 1099)	θ value	3.0926 (rank : 1171)
Query Neighborhood Hits	1371	Target Neighborhood Hits	483	Shared Neighborhood Hits	296
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

WWC1_HUMAN
NC score	0.148932 (rank : 1100)	θ value	θ > 10 (rank : 2332)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	203
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

MINT_HUMAN
NC score	0.148594 (rank : 1101)	θ value	0.21417 (rank : 853)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1291	Shared Neighborhood Hits	327
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RASA1_HUMAN
NC score	0.148408 (rank : 1102)	θ value	8.99809 (rank : 1356)
Query Neighborhood Hits	1371	Target Neighborhood Hits	258	Shared Neighborhood Hits	127
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

TNIK_HUMAN
NC score	0.148392 (rank : 1103)	θ value	8.99809 (rank : 1364)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1570	Shared Neighborhood Hits	544
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

WWC1_MOUSE
NC score	0.148374 (rank : 1104)	θ value	θ > 10 (rank : 2333)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	199
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

K1C23_MOUSE
NC score	0.148329 (rank : 1105)	θ value	8.99809 (rank : 1337)
Query Neighborhood Hits	1371	Target Neighborhood Hits	370	Shared Neighborhood Hits	287
SwissProt Accessions	Q99PS0	Gene names	Krt23, Haik1, Krt1-23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

SYT4_MOUSE
NC score	0.148320 (rank : 1106)	θ value	2.36792 (rank : 1161)
Query Neighborhood Hits	1371	Target Neighborhood Hits	123	Shared Neighborhood Hits	81
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

CYLC1_HUMAN
NC score	0.148106 (rank : 1107)	θ value	θ > 10 (rank : 1563)
Query Neighborhood Hits	1371	Target Neighborhood Hits	408	Shared Neighborhood Hits	170
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

MYO7A_MOUSE
NC score	0.148068 (rank : 1108)	θ value	θ > 10 (rank : 1945)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	156
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CEP72_HUMAN
NC score	0.147848 (rank : 1109)	θ value	θ > 10 (rank : 1508)
Query Neighborhood Hits	1371	Target Neighborhood Hits	374	Shared Neighborhood Hits	202
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

DTBP1_MOUSE
NC score	0.147714 (rank : 1110)	θ value	θ > 10 (rank : 1596)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	165
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

SYTL5_HUMAN
NC score	0.147664 (rank : 1111)	θ value	0.00390308 (rank : 572)
Query Neighborhood Hits	1371	Target Neighborhood Hits	237	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

HGS_HUMAN
NC score	0.147486 (rank : 1112)	θ value	θ > 10 (rank : 1719)
Query Neighborhood Hits	1371	Target Neighborhood Hits	517	Shared Neighborhood Hits	194
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

CM007_MOUSE
NC score	0.147259 (rank : 1113)	θ value	0.365318 (rank : 898)
Query Neighborhood Hits	1371	Target Neighborhood Hits	416	Shared Neighborhood Hits	178
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

F107B_HUMAN
NC score	0.147222 (rank : 1114)	θ value	θ > 10 (rank : 1648)
Query Neighborhood Hits	1371	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

MPP10_MOUSE
NC score	0.146989 (rank : 1115)	θ value	θ > 10 (rank : 1924)
Query Neighborhood Hits	1371	Target Neighborhood Hits	251	Shared Neighborhood Hits	166
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

TFAP4_HUMAN
NC score	0.146921 (rank : 1116)	θ value	θ > 10 (rank : 2267)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	164
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

SYT11_MOUSE
NC score	0.146905 (rank : 1117)	θ value	1.81305 (rank : 1113)
Query Neighborhood Hits	1371	Target Neighborhood Hits	116	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
NC score	0.146892 (rank : 1118)	θ value	1.81305 (rank : 1112)
Query Neighborhood Hits	1371	Target Neighborhood Hits	113	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

ATRIP_HUMAN
NC score	0.146849 (rank : 1119)	θ value	4.03905 (rank : 1197)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	194
SwissProt Accessions	Q8WXE1, Q8NHQ2, Q8WUG7, Q96CL3, Q9HA30	Gene names	ATRIP
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

K1C12_MOUSE
NC score	0.146846 (rank : 1120)	θ value	θ > 10 (rank : 1775)
Query Neighborhood Hits	1371	Target Neighborhood Hits	409	Shared Neighborhood Hits	313
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

STS1_MOUSE
NC score	0.146799 (rank : 1121)	θ value	0.0252991 (rank : 690)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

CCD55_HUMAN
NC score	0.146367 (rank : 1122)	θ value	θ > 10 (rank : 1483)
Query Neighborhood Hits	1371	Target Neighborhood Hits	513	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

F107B_MOUSE
NC score	0.146197 (rank : 1123)	θ value	θ > 10 (rank : 1649)
Query Neighborhood Hits	1371	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

STS1_HUMAN
NC score	0.146051 (rank : 1124)	θ value	0.0330416 (rank : 702)
Query Neighborhood Hits	1371	Target Neighborhood Hits	106	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

EXOC1_MOUSE
NC score	0.146017 (rank : 1125)	θ value	0.0193708 (rank : 662)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	149
SwissProt Accessions	Q8R3S6	Gene names	Exoc1, Sec3, Sec3l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

TAF3_MOUSE
NC score	0.145768 (rank : 1126)	θ value	θ > 10 (rank : 2247)
Query Neighborhood Hits	1371	Target Neighborhood Hits	463	Shared Neighborhood Hits	218
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

BTK_HUMAN
NC score	0.145766 (rank : 1127)	θ value	2.88788e-06 (rank : 255)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1026	Shared Neighborhood Hits	256
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

LRRF1_MOUSE
NC score	0.145415 (rank : 1128)	θ value	θ > 10 (rank : 1886)
Query Neighborhood Hits	1371	Target Neighborhood Hits	440	Shared Neighborhood Hits	221
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

TRAF3_MOUSE
NC score	0.145146 (rank : 1129)	θ value	0.0961366 (rank : 801)
Query Neighborhood Hits	1371	Target Neighborhood Hits	476	Shared Neighborhood Hits	266
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

HGS_MOUSE
NC score	0.144995 (rank : 1130)	θ value	θ > 10 (rank : 1720)
Query Neighborhood Hits	1371	Target Neighborhood Hits	589	Shared Neighborhood Hits	198
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CCNB3_HUMAN
NC score	0.144802 (rank : 1131)	θ value	θ > 10 (rank : 1492)
Query Neighborhood Hits	1371	Target Neighborhood Hits	368	Shared Neighborhood Hits	207
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

K22O_HUMAN
NC score	0.144787 (rank : 1132)	θ value	θ > 10 (rank : 1792)
Query Neighborhood Hits	1371	Target Neighborhood Hits	485	Shared Neighborhood Hits	319
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

SMCE1_HUMAN
NC score	0.144474 (rank : 1133)	θ value	0.21417 (rank : 864)
Query Neighborhood Hits	1371	Target Neighborhood Hits	272	Shared Neighborhood Hits	144
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

BAIP3_MOUSE
NC score	0.144382 (rank : 1134)	θ value	0.0563607 (rank : 721)
Query Neighborhood Hits	1371	Target Neighborhood Hits	112	Shared Neighborhood Hits	81
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

MPP6_HUMAN
NC score	0.144281 (rank : 1135)	θ value	4.1701e-05 (rank : 363)
Query Neighborhood Hits	1371	Target Neighborhood Hits	180	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

EM55_HUMAN
NC score	0.143945 (rank : 1136)	θ value	0.000786445 (rank : 481)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	114
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

SYTL4_MOUSE
NC score	0.143837 (rank : 1137)	θ value	0.0252991 (rank : 692)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

GBP2_MOUSE
NC score	0.143742 (rank : 1138)	θ value	θ > 10 (rank : 1690)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

USH1C_MOUSE
NC score	0.143697 (rank : 1139)	θ value	0.279714 (rank : 893)
Query Neighborhood Hits	1371	Target Neighborhood Hits	557	Shared Neighborhood Hits	261
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

BAIP3_HUMAN
NC score	0.143613 (rank : 1140)	θ value	0.0193708 (rank : 655)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	78
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

M3K11_HUMAN
NC score	0.143374 (rank : 1141)	θ value	1.29631e-06 (rank : 231)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1136	Shared Neighborhood Hits	275
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PA24D_HUMAN
NC score	0.143005 (rank : 1142)	θ value	4.1701e-05 (rank : 365)
Query Neighborhood Hits	1371	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

TRAF3_HUMAN
NC score	0.142862 (rank : 1143)	θ value	0.0961366 (rank : 800)
Query Neighborhood Hits	1371	Target Neighborhood Hits	463	Shared Neighborhood Hits	265
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

M3K9_HUMAN
NC score	0.142824 (rank : 1144)	θ value	2.21117e-06 (rank : 247)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1123	Shared Neighborhood Hits	293
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

LAMA4_MOUSE
NC score	0.142567 (rank : 1145)	θ value	θ > 10 (rank : 1862)
Query Neighborhood Hits	1371	Target Neighborhood Hits	584	Shared Neighborhood Hits	261
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

STX1C_HUMAN
NC score	0.142415 (rank : 1146)	θ value	θ > 10 (rank : 2209)
Query Neighborhood Hits	1371	Target Neighborhood Hits	270	Shared Neighborhood Hits	215
SwissProt Accessions	P61266	Gene names	STX1B2
Domain Architecture
Description	Syntaxin-1B2.

STX1C_MOUSE
NC score	0.142415 (rank : 1147)	θ value	θ > 10 (rank : 2210)
Query Neighborhood Hits	1371	Target Neighborhood Hits	270	Shared Neighborhood Hits	215
SwissProt Accessions	P61264, P32853	Gene names	Stx1b2, Stx1b
Domain Architecture
Description	Syntaxin-1B2 (Syntaxin 1B).

BTK_MOUSE
NC score	0.142300 (rank : 1148)	θ value	2.21117e-06 (rank : 244)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1017	Shared Neighborhood Hits	245
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

ANR11_HUMAN
NC score	0.142158 (rank : 1149)	θ value	1.81305 (rank : 1078)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1289	Shared Neighborhood Hits	400
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CENPQ_MOUSE
NC score	0.141972 (rank : 1150)	θ value	θ > 10 (rank : 1504)
Query Neighborhood Hits	1371	Target Neighborhood Hits	160	Shared Neighborhood Hits	132
SwissProt Accessions	Q9CPQ5, Q8C2G4, Q8VEF8, Q9CX70	Gene names	Cenpq
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

LAMC2_HUMAN
NC score	0.141902 (rank : 1151)	θ value	θ > 10 (rank : 1868)
Query Neighborhood Hits	1371	Target Neighborhood Hits	715	Shared Neighborhood Hits	279
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

TMCC1_HUMAN
NC score	0.141826 (rank : 1152)	θ value	8.99809 (rank : 1363)
Query Neighborhood Hits	1371	Target Neighborhood Hits	337	Shared Neighborhood Hits	248
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

CENPQ_HUMAN
NC score	0.141810 (rank : 1153)	θ value	0.62314 (rank : 961)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	103
SwissProt Accessions	Q7L2Z9, Q6IN61, Q9NVS5	Gene names	CENPQ, C6orf139
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

MPP6_MOUSE
NC score	0.140900 (rank : 1154)	θ value	5.44631e-05 (rank : 375)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

HCK_HUMAN
NC score	0.140623 (rank : 1155)	θ value	2.44474e-05 (rank : 341)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1035	Shared Neighborhood Hits	244
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
NC score	0.140533 (rank : 1156)	θ value	1.43324e-05 (rank : 314)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1029	Shared Neighborhood Hits	243
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

SRC_MOUSE
NC score	0.140483 (rank : 1157)	θ value	1.29631e-06 (rank : 237)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1033	Shared Neighborhood Hits	235
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

CCD38_MOUSE
NC score	0.140443 (rank : 1158)	θ value	θ > 10 (rank : 1479)
Query Neighborhood Hits	1371	Target Neighborhood Hits	165	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CDN8, Q8CDD6, Q8CDE1	Gene names	Ccdc38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

TEKT2_HUMAN
NC score	0.140374 (rank : 1159)	θ value	θ > 10 (rank : 2262)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

MYO7A_HUMAN
NC score	0.140362 (rank : 1160)	θ value	θ > 10 (rank : 1944)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	132
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CLSPN_HUMAN
NC score	0.140039 (rank : 1161)	θ value	θ > 10 (rank : 1533)
Query Neighborhood Hits	1371	Target Neighborhood Hits	433	Shared Neighborhood Hits	244
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

KI13B_HUMAN
NC score	0.139909 (rank : 1162)	θ value	2.36792 (rank : 1143)
Query Neighborhood Hits	1371	Target Neighborhood Hits	492	Shared Neighborhood Hits	291
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

SOS1_HUMAN
NC score	0.139886 (rank : 1163)	θ value	θ > 10 (rank : 2172)
Query Neighborhood Hits	1371	Target Neighborhood Hits	274	Shared Neighborhood Hits	71
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

BIN3_MOUSE
NC score	0.139755 (rank : 1164)	θ value	θ > 10 (rank : 1452)
Query Neighborhood Hits	1371	Target Neighborhood Hits	165	Shared Neighborhood Hits	143
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

K1C13_HUMAN
NC score	0.139707 (rank : 1165)	θ value	θ > 10 (rank : 1776)
Query Neighborhood Hits	1371	Target Neighborhood Hits	386	Shared Neighborhood Hits	302
SwissProt Accessions	P13646, Q53G54, Q6AZK5, Q8N240	Gene names	KRT13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13).

CT151_HUMAN
NC score	0.139645 (rank : 1166)	θ value	θ > 10 (rank : 1555)
Query Neighborhood Hits	1371	Target Neighborhood Hits	382	Shared Neighborhood Hits	170
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

SFR17_HUMAN
NC score	0.139420 (rank : 1167)	θ value	8.99809 (rank : 1360)
Query Neighborhood Hits	1371	Target Neighborhood Hits	325	Shared Neighborhood Hits	173
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

OTU6B_MOUSE
NC score	0.139161 (rank : 1168)	θ value	5.27518 (rank : 1255)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	171
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

MAT1_MOUSE
NC score	0.138942 (rank : 1169)	θ value	θ > 10 (rank : 1901)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	158
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

TAF3_HUMAN
NC score	0.138832 (rank : 1170)	θ value	θ > 10 (rank : 2246)
Query Neighborhood Hits	1371	Target Neighborhood Hits	568	Shared Neighborhood Hits	234
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

NTBP1_HUMAN
NC score	0.138626 (rank : 1171)	θ value	θ > 10 (rank : 1987)
Query Neighborhood Hits	1371	Target Neighborhood Hits	171	Shared Neighborhood Hits	145
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

MYO9B_HUMAN
NC score	0.138533 (rank : 1172)	θ value	θ > 10 (rank : 1946)
Query Neighborhood Hits	1371	Target Neighborhood Hits	641	Shared Neighborhood Hits	171
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

BAP31_HUMAN
NC score	0.138358 (rank : 1173)	θ value	θ > 10 (rank : 1436)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	190
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

EM55_MOUSE
NC score	0.138274 (rank : 1174)	θ value	0.00869519 (rank : 605)
Query Neighborhood Hits	1371	Target Neighborhood Hits	221	Shared Neighborhood Hits	112
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

UN84B_MOUSE
NC score	0.138046 (rank : 1175)	θ value	0.00509761 (rank : 588)
Query Neighborhood Hits	1371	Target Neighborhood Hits	194	Shared Neighborhood Hits	156
SwissProt Accessions	Q8BJS4	Gene names	Unc84b, Sun2
Domain Architecture	No domain graphic available
Description	Sad1/unc-84-like protein 2.

DNJC8_MOUSE
NC score	0.138018 (rank : 1176)	θ value	0.0252991 (rank : 676)
Query Neighborhood Hits	1371	Target Neighborhood Hits	392	Shared Neighborhood Hits	193
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

KRHB6_HUMAN
NC score	0.137951 (rank : 1177)	θ value	θ > 10 (rank : 1851)
Query Neighborhood Hits	1371	Target Neighborhood Hits	447	Shared Neighborhood Hits	310
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

SYTL5_MOUSE
NC score	0.137817 (rank : 1178)	θ value	θ > 10 (rank : 2238)
Query Neighborhood Hits	1371	Target Neighborhood Hits	154	Shared Neighborhood Hits	79
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

EXOC1_HUMAN
NC score	0.137405 (rank : 1179)	θ value	0.0563607 (rank : 730)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NV70, Q8WUE7, Q96T15, Q9NZE4	Gene names	EXOC1, SEC3, SEC3L1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

FER_HUMAN
NC score	0.137392 (rank : 1180)	θ value	0.47712 (rank : 939)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1278	Shared Neighborhood Hits	432
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

GCP6_HUMAN
NC score	0.137390 (rank : 1181)	θ value	1.38821 (rank : 1051)
Query Neighborhood Hits	1371	Target Neighborhood Hits	295	Shared Neighborhood Hits	178
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

AKAP6_HUMAN
NC score	0.136823 (rank : 1182)	θ value	θ > 10 (rank : 1396)
Query Neighborhood Hits	1371	Target Neighborhood Hits	263	Shared Neighborhood Hits	131
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

KRHB1_HUMAN
NC score	0.136707 (rank : 1183)	θ value	θ > 10 (rank : 1843)
Query Neighborhood Hits	1371	Target Neighborhood Hits	461	Shared Neighborhood Hits	311
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

CHCH3_HUMAN
NC score	0.136487 (rank : 1184)	θ value	θ > 10 (rank : 1513)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NX63	Gene names	CHCHD3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CD72_MOUSE
NC score	0.136461 (rank : 1185)	θ value	θ > 10 (rank : 1496)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	171
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

KIF17_MOUSE
NC score	0.136315 (rank : 1186)	θ value	θ > 10 (rank : 1813)
Query Neighborhood Hits	1371	Target Neighborhood Hits	452	Shared Neighborhood Hits	276
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

LAMA3_MOUSE
NC score	0.136314 (rank : 1187)	θ value	θ > 10 (rank : 1860)
Query Neighborhood Hits	1371	Target Neighborhood Hits	859	Shared Neighborhood Hits	321
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

ZN318_HUMAN
NC score	0.136025 (rank : 1188)	θ value	0.47712 (rank : 957)
Query Neighborhood Hits	1371	Target Neighborhood Hits	497	Shared Neighborhood Hits	231
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

KIF6_HUMAN
NC score	0.135643 (rank : 1189)	θ value	0.365318 (rank : 909)
Query Neighborhood Hits	1371	Target Neighborhood Hits	271	Shared Neighborhood Hits	199
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

CCDC5_HUMAN
NC score	0.135197 (rank : 1190)	θ value	0.813845 (rank : 976)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	114
SwissProt Accessions	Q96CS2, Q8N837	Gene names	CCDC5, HEIC
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5 (Enhancer of invasion-cluster) (HEI-C).

ATRIP_MOUSE
NC score	0.134984 (rank : 1191)	θ value	θ > 10 (rank : 1433)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	191
SwissProt Accessions	Q8BMG1	Gene names	Atrip
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

K1C15_HUMAN
NC score	0.134961 (rank : 1192)	θ value	θ > 10 (rank : 1780)
Query Neighborhood Hits	1371	Target Neighborhood Hits	367	Shared Neighborhood Hits	284
SwissProt Accessions	P19012, Q53XV8, Q9BUG4	Gene names	KRT15, KRTB
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

LYN_HUMAN
NC score	0.134850 (rank : 1193)	θ value	9.92553e-07 (rank : 223)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1022	Shared Neighborhood Hits	226
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

SOS1_MOUSE
NC score	0.134493 (rank : 1194)	θ value	θ > 10 (rank : 2173)
Query Neighborhood Hits	1371	Target Neighborhood Hits	281	Shared Neighborhood Hits	76
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

CF118_HUMAN
NC score	0.134280 (rank : 1195)	θ value	θ > 10 (rank : 1511)
Query Neighborhood Hits	1371	Target Neighborhood Hits	154	Shared Neighborhood Hits	120
SwissProt Accessions	Q5T5N4, Q8TC11	Gene names	C6orf118
Domain Architecture	No domain graphic available
Description	Protein C6orf118.

MYO9B_MOUSE
NC score	0.134242 (rank : 1196)	θ value	θ > 10 (rank : 1947)
Query Neighborhood Hits	1371	Target Neighborhood Hits	311	Shared Neighborhood Hits	121
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SH24A_MOUSE
NC score	0.134217 (rank : 1197)	θ value	0.47712 (rank : 950)
Query Neighborhood Hits	1371	Target Neighborhood Hits	326	Shared Neighborhood Hits	182
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

KI13A_MOUSE
NC score	0.134181 (rank : 1198)	θ value	1.81305 (rank : 1094)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	260
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

K2C3_HUMAN
NC score	0.133930 (rank : 1199)	θ value	θ > 10 (rank : 1793)
Query Neighborhood Hits	1371	Target Neighborhood Hits	443	Shared Neighborhood Hits	287
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

OTU6B_HUMAN
NC score	0.133832 (rank : 1200)	θ value	θ > 10 (rank : 1998)
Query Neighborhood Hits	1371	Target Neighborhood Hits	182	Shared Neighborhood Hits	155
SwissProt Accessions	Q8N6M0, Q9NTA4, Q9Y387	Gene names	OTUD6B
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

ANGP2_MOUSE
NC score	0.133816 (rank : 1201)	θ value	θ > 10 (rank : 1405)
Query Neighborhood Hits	1371	Target Neighborhood Hits	397	Shared Neighborhood Hits	289
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

BIN1_MOUSE
NC score	0.133806 (rank : 1202)	θ value	θ > 10 (rank : 1450)
Query Neighborhood Hits	1371	Target Neighborhood Hits	283	Shared Neighborhood Hits	139
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

K1C12_HUMAN
NC score	0.133781 (rank : 1203)	θ value	θ > 10 (rank : 1774)
Query Neighborhood Hits	1371	Target Neighborhood Hits	372	Shared Neighborhood Hits	287
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

LYN_MOUSE
NC score	0.133696 (rank : 1204)	θ value	7.59969e-07 (rank : 219)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1023	Shared Neighborhood Hits	227
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

SYTL2_MOUSE
NC score	0.133630 (rank : 1205)	θ value	5.27518 (rank : 1268)
Query Neighborhood Hits	1371	Target Neighborhood Hits	253	Shared Neighborhood Hits	98
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

KRHB3_HUMAN
NC score	0.133542 (rank : 1206)	θ value	θ > 10 (rank : 1846)
Query Neighborhood Hits	1371	Target Neighborhood Hits	438	Shared Neighborhood Hits	305
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

TEX14_MOUSE
NC score	0.133500 (rank : 1207)	θ value	θ > 10 (rank : 2266)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1333	Shared Neighborhood Hits	349
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

SYTL2_HUMAN
NC score	0.133303 (rank : 1208)	θ value	θ > 10 (rank : 2236)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYBU_MOUSE
NC score	0.133137 (rank : 1209)	θ value	θ > 10 (rank : 2223)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	142
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

SYTL1_HUMAN
NC score	0.133109 (rank : 1210)	θ value	0.0961366 (rank : 797)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

LC7L2_MOUSE
NC score	0.133090 (rank : 1211)	θ value	θ > 10 (rank : 1873)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	171
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

BIN1_HUMAN
NC score	0.132579 (rank : 1212)	θ value	θ > 10 (rank : 1449)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	137
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

MINK1_HUMAN
NC score	0.132506 (rank : 1213)	θ value	0.0736092 (rank : 759)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1477	Shared Neighborhood Hits	507
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

APOE_HUMAN
NC score	0.132458 (rank : 1214)	θ value	θ > 10 (rank : 1422)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	151
SwissProt Accessions	P02649, Q9P2S4	Gene names	APOE
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

G45IP_HUMAN
NC score	0.132358 (rank : 1215)	θ value	1.81305 (rank : 1091)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

M3K10_HUMAN
NC score	0.132349 (rank : 1216)	θ value	0.000121331 (rank : 398)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1071	Shared Neighborhood Hits	280
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

RSF1_HUMAN
NC score	0.132121 (rank : 1217)	θ value	θ > 10 (rank : 2105)
Query Neighborhood Hits	1371	Target Neighborhood Hits	539	Shared Neighborhood Hits	220
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RHG25_MOUSE
NC score	0.132090 (rank : 1218)	θ value	θ > 10 (rank : 2079)
Query Neighborhood Hits	1371	Target Neighborhood Hits	492	Shared Neighborhood Hits	234
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

KLC1_MOUSE
NC score	0.132041 (rank : 1219)	θ value	θ > 10 (rank : 1831)
Query Neighborhood Hits	1371	Target Neighborhood Hits	357	Shared Neighborhood Hits	254
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

GOPC_HUMAN
NC score	0.131977 (rank : 1220)	θ value	1.38821 (rank : 1052)
Query Neighborhood Hits	1371	Target Neighborhood Hits	377	Shared Neighborhood Hits	198
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

EXOC5_HUMAN
NC score	0.131861 (rank : 1221)	θ value	2.36792 (rank : 1136)
Query Neighborhood Hits	1371	Target Neighborhood Hits	194	Shared Neighborhood Hits	153
SwissProt Accessions	O00471	Gene names	EXOC5, SEC10, SEC10L1
Domain Architecture
Description	Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10).

GBP1_MOUSE
NC score	0.131858 (rank : 1222)	θ value	θ > 10 (rank : 1688)
Query Neighborhood Hits	1371	Target Neighborhood Hits	302	Shared Neighborhood Hits	225
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

MINK1_MOUSE
NC score	0.131792 (rank : 1223)	θ value	0.21417 (rank : 852)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1451	Shared Neighborhood Hits	502
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

NCOR2_MOUSE
NC score	0.131742 (rank : 1224)	θ value	1.06291 (rank : 1021)
Query Neighborhood Hits	1371	Target Neighborhood Hits	790	Shared Neighborhood Hits	274
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

EXOC5_MOUSE
NC score	0.131686 (rank : 1225)	θ value	1.81305 (rank : 1090)
Query Neighborhood Hits	1371	Target Neighborhood Hits	194	Shared Neighborhood Hits	152
SwissProt Accessions	Q3TPX4	Gene names	Exoc5, Sec10l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 5 (Exocyst complex component Sec10).

HM20A_MOUSE
NC score	0.131473 (rank : 1226)	θ value	0.813845 (rank : 980)
Query Neighborhood Hits	1371	Target Neighborhood Hits	348	Shared Neighborhood Hits	202
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

K2C7_HUMAN
NC score	0.131436 (rank : 1227)	θ value	θ > 10 (rank : 1801)
Query Neighborhood Hits	1371	Target Neighborhood Hits	369	Shared Neighborhood Hits	272
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

CD72_HUMAN
NC score	0.131368 (rank : 1228)	θ value	θ > 10 (rank : 1495)
Query Neighborhood Hits	1371	Target Neighborhood Hits	345	Shared Neighborhood Hits	199
SwissProt Accessions	P21854	Gene names	CD72
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2).

SNX9_MOUSE
NC score	0.131281 (rank : 1229)	θ value	θ > 10 (rank : 2169)
Query Neighborhood Hits	1371	Target Neighborhood Hits	141	Shared Neighborhood Hits	99
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

DJC17_HUMAN
NC score	0.131166 (rank : 1230)	θ value	θ > 10 (rank : 1587)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	231
SwissProt Accessions	Q9NVM6	Gene names	DNAJC17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

EMIL3_MOUSE
NC score	0.131051 (rank : 1231)	θ value	θ > 10 (rank : 1616)
Query Neighborhood Hits	1371	Target Neighborhood Hits	240	Shared Neighborhood Hits	167
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

TJAP1_HUMAN
NC score	0.130964 (rank : 1232)	θ value	2.36792 (rank : 1162)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	145
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

PFD6_MOUSE
NC score	0.130955 (rank : 1233)	θ value	θ > 10 (rank : 2018)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	120
SwissProt Accessions	Q03958	Gene names	Pfdn6, H2-Ke2, Pfd6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

LC7L2_HUMAN
NC score	0.130856 (rank : 1234)	θ value	θ > 10 (rank : 1872)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

CN140_MOUSE
NC score	0.130516 (rank : 1235)	θ value	0.00228821 (rank : 531)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	117
SwissProt Accessions	Q8CCG1, Q8CCM8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf140 homolog.

ANGP2_HUMAN
NC score	0.130406 (rank : 1236)	θ value	θ > 10 (rank : 1404)
Query Neighborhood Hits	1371	Target Neighborhood Hits	400	Shared Neighborhood Hits	283
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

FRK_HUMAN
NC score	0.130091 (rank : 1237)	θ value	0.0113563 (rank : 622)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1058	Shared Neighborhood Hits	260
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

CCD55_MOUSE
NC score	0.129468 (rank : 1238)	θ value	θ > 10 (rank : 1484)
Query Neighborhood Hits	1371	Target Neighborhood Hits	519	Shared Neighborhood Hits	201
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ZN365_MOUSE
NC score	0.129071 (rank : 1239)	θ value	5.27518 (rank : 1277)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	145
SwissProt Accessions	Q8BG89, Q80TQ4, Q8BK39, Q8BXT2	Gene names	Znf365, Kiaa0844, Zfp365
Domain Architecture	No domain graphic available
Description	Protein ZNF365 (Su48).

TMCC1_MOUSE
NC score	0.129005 (rank : 1240)	θ value	θ > 10 (rank : 2274)
Query Neighborhood Hits	1371	Target Neighborhood Hits	315	Shared Neighborhood Hits	236
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

BLK_HUMAN
NC score	0.128983 (rank : 1241)	θ value	0.00175202 (rank : 511)
Query Neighborhood Hits	1371	Target Neighborhood Hits	994	Shared Neighborhood Hits	211
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

RIMS2_HUMAN
NC score	0.128937 (rank : 1242)	θ value	0.813845 (rank : 993)
Query Neighborhood Hits	1371	Target Neighborhood Hits	342	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

HM20A_HUMAN
NC score	0.128928 (rank : 1243)	θ value	1.06291 (rank : 1015)
Query Neighborhood Hits	1371	Target Neighborhood Hits	343	Shared Neighborhood Hits	201
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

MED12_HUMAN
NC score	0.128894 (rank : 1244)	θ value	θ > 10 (rank : 1905)
Query Neighborhood Hits	1371	Target Neighborhood Hits	262	Shared Neighborhood Hits	145
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

RIMS2_MOUSE
NC score	0.128799 (rank : 1245)	θ value	0.813845 (rank : 994)
Query Neighborhood Hits	1371	Target Neighborhood Hits	376	Shared Neighborhood Hits	149
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

UBP8_HUMAN
NC score	0.128770 (rank : 1246)	θ value	6.88961 (rank : 1323)
Query Neighborhood Hits	1371	Target Neighborhood Hits	751	Shared Neighborhood Hits	403
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

DNJC8_HUMAN
NC score	0.128716 (rank : 1247)	θ value	0.0252991 (rank : 675)
Query Neighborhood Hits	1371	Target Neighborhood Hits	380	Shared Neighborhood Hits	181
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

STX12_HUMAN
NC score	0.128604 (rank : 1248)	θ value	θ > 10 (rank : 2203)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	172
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

SEPT7_HUMAN
NC score	0.128476 (rank : 1249)	θ value	0.279714 (rank : 889)
Query Neighborhood Hits	1371	Target Neighborhood Hits	385	Shared Neighborhood Hits	289
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

TSKS_HUMAN
NC score	0.128422 (rank : 1250)	θ value	θ > 10 (rank : 2298)
Query Neighborhood Hits	1371	Target Neighborhood Hits	220	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

MYO15_MOUSE
NC score	0.128399 (rank : 1251)	θ value	8.99809 (rank : 1344)
Query Neighborhood Hits	1371	Target Neighborhood Hits	467	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RIMS1_HUMAN
NC score	0.128129 (rank : 1252)	θ value	0.0736092 (rank : 764)
Query Neighborhood Hits	1371	Target Neighborhood Hits	437	Shared Neighborhood Hits	132
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

TRIM8_HUMAN
NC score	0.128051 (rank : 1253)	θ value	0.0961366 (rank : 803)
Query Neighborhood Hits	1371	Target Neighborhood Hits	650	Shared Neighborhood Hits	299
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

EMIL2_MOUSE
NC score	0.127724 (rank : 1254)	θ value	θ > 10 (rank : 1614)
Query Neighborhood Hits	1371	Target Neighborhood Hits	485	Shared Neighborhood Hits	200
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

SYT8_MOUSE
NC score	0.127509 (rank : 1255)	θ value	θ > 10 (rank : 2235)
Query Neighborhood Hits	1371	Target Neighborhood Hits	94	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

TRIM8_MOUSE
NC score	0.127449 (rank : 1256)	θ value	0.163984 (rank : 838)
Query Neighborhood Hits	1371	Target Neighborhood Hits	674	Shared Neighborhood Hits	317
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

SGOL2_HUMAN
NC score	0.127398 (rank : 1257)	θ value	θ > 10 (rank : 2133)
Query Neighborhood Hits	1371	Target Neighborhood Hits	207	Shared Neighborhood Hits	122
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

DOT1L_HUMAN
NC score	0.127353 (rank : 1258)	θ value	θ > 10 (rank : 1593)
Query Neighborhood Hits	1371	Target Neighborhood Hits	660	Shared Neighborhood Hits	182
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

BLK_MOUSE
NC score	0.127179 (rank : 1259)	θ value	0.00102713 (rank : 494)
Query Neighborhood Hits	1371	Target Neighborhood Hits	992	Shared Neighborhood Hits	202
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

HIRP3_HUMAN
NC score	0.127063 (rank : 1260)	θ value	θ > 10 (rank : 1721)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	154
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

MYO15_HUMAN
NC score	0.126640 (rank : 1261)	θ value	1.81305 (rank : 1102)
Query Neighborhood Hits	1371	Target Neighborhood Hits	671	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PDCD7_HUMAN
NC score	0.126631 (rank : 1262)	θ value	θ > 10 (rank : 2010)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	141
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

RFIP1_MOUSE
NC score	0.126582 (rank : 1263)	θ value	0.000158464 (rank : 414)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

NED4L_HUMAN
NC score	0.126032 (rank : 1264)	θ value	2.21117e-06 (rank : 251)
Query Neighborhood Hits	1371	Target Neighborhood Hits	238	Shared Neighborhood Hits	101
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

K1C19_MOUSE
NC score	0.125828 (rank : 1265)	θ value	θ > 10 (rank : 1785)
Query Neighborhood Hits	1371	Target Neighborhood Hits	358	Shared Neighborhood Hits	277
SwissProt Accessions	P19001	Gene names	Krt19, Krt1-19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

NED4L_MOUSE
NC score	0.125771 (rank : 1266)	θ value	2.21117e-06 (rank : 252)
Query Neighborhood Hits	1371	Target Neighborhood Hits	231	Shared Neighborhood Hits	103
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

TEC_HUMAN
NC score	0.125411 (rank : 1267)	θ value	5.44631e-05 (rank : 377)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1006	Shared Neighborhood Hits	218
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

RP1L1_HUMAN
NC score	0.125344 (rank : 1268)	θ value	θ > 10 (rank : 2104)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1072	Shared Neighborhood Hits	253
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

DTBP1_HUMAN
NC score	0.124889 (rank : 1269)	θ value	θ > 10 (rank : 1595)
Query Neighborhood Hits	1371	Target Neighborhood Hits	185	Shared Neighborhood Hits	143
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

SAFB1_HUMAN
NC score	0.124773 (rank : 1270)	θ value	0.365318 (rank : 921)
Query Neighborhood Hits	1371	Target Neighborhood Hits	493	Shared Neighborhood Hits	215
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

KRHB6_MOUSE
NC score	0.124687 (rank : 1271)	θ value	θ > 10 (rank : 1852)
Query Neighborhood Hits	1371	Target Neighborhood Hits	413	Shared Neighborhood Hits	289
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

TXK_MOUSE
NC score	0.124328 (rank : 1272)	θ value	0.000121331 (rank : 407)
Query Neighborhood Hits	1371	Target Neighborhood Hits	980	Shared Neighborhood Hits	214
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

PKHA6_MOUSE
NC score	0.124139 (rank : 1273)	θ value	θ > 10 (rank : 2023)
Query Neighborhood Hits	1371	Target Neighborhood Hits	591	Shared Neighborhood Hits	213
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

NONO_HUMAN
NC score	0.123891 (rank : 1274)	θ value	8.99809 (rank : 1347)
Query Neighborhood Hits	1371	Target Neighborhood Hits	441	Shared Neighborhood Hits	209
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

PA24B_MOUSE
NC score	0.123869 (rank : 1275)	θ value	0.0252991 (rank : 687)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	75
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SYTL1_MOUSE
NC score	0.123764 (rank : 1276)	θ value	1.06291 (rank : 1035)
Query Neighborhood Hits	1371	Target Neighborhood Hits	314	Shared Neighborhood Hits	101
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TEC_MOUSE
NC score	0.123407 (rank : 1277)	θ value	1.87187e-05 (rank : 338)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1006	Shared Neighborhood Hits	215
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

NONO_MOUSE
NC score	0.123134 (rank : 1278)	θ value	8.99809 (rank : 1348)
Query Neighborhood Hits	1371	Target Neighborhood Hits	444	Shared Neighborhood Hits	209
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

AKA12_HUMAN
NC score	0.123109 (rank : 1279)	θ value	θ > 10 (rank : 1394)
Query Neighborhood Hits	1371	Target Neighborhood Hits	825	Shared Neighborhood Hits	251
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

K1C23_HUMAN
NC score	0.123043 (rank : 1280)	θ value	θ > 10 (rank : 1786)
Query Neighborhood Hits	1371	Target Neighborhood Hits	312	Shared Neighborhood Hits	239
SwissProt Accessions	Q9C075, Q9NUR6	Gene names	KRT23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

SYNG_MOUSE
NC score	0.122940 (rank : 1281)	θ value	0.00175202 (rank : 525)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	57
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

RUSC2_HUMAN
NC score	0.122721 (rank : 1282)	θ value	0.00665767 (rank : 601)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SEPT7_MOUSE
NC score	0.122407 (rank : 1283)	θ value	0.47712 (rank : 948)
Query Neighborhood Hits	1371	Target Neighborhood Hits	327	Shared Neighborhood Hits	247
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

NCOR2_HUMAN
NC score	0.122266 (rank : 1284)	θ value	0.813845 (rank : 987)
Query Neighborhood Hits	1371	Target Neighborhood Hits	870	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

DAPP1_MOUSE
NC score	0.122057 (rank : 1285)	θ value	θ > 10 (rank : 1571)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

MORC4_HUMAN
NC score	0.121681 (rank : 1286)	θ value	θ > 10 (rank : 1918)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	186
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

DYDC1_HUMAN
NC score	0.121656 (rank : 1287)	θ value	θ > 10 (rank : 1600)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	114
SwissProt Accessions	Q8WWB3, Q5QP03, Q5QP04, Q6WNP4, Q6ZU87	Gene names	DYDC1, DPY30D1
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 1 (RSD-9).

DAPP1_HUMAN
NC score	0.121652 (rank : 1288)	θ value	θ > 10 (rank : 1570)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

KI13A_HUMAN
NC score	0.121416 (rank : 1289)	θ value	0.163984 (rank : 831)
Query Neighborhood Hits	1371	Target Neighborhood Hits	359	Shared Neighborhood Hits	232
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

PPIG_HUMAN
NC score	0.121311 (rank : 1290)	θ value	θ > 10 (rank : 2039)
Query Neighborhood Hits	1371	Target Neighborhood Hits	670	Shared Neighborhood Hits	281
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

CN044_HUMAN
NC score	0.121293 (rank : 1291)	θ value	θ > 10 (rank : 1538)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	161
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

PRP40_HUMAN
NC score	0.121277 (rank : 1292)	θ value	θ > 10 (rank : 2042)
Query Neighborhood Hits	1371	Target Neighborhood Hits	442	Shared Neighborhood Hits	206
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

NOL10_MOUSE
NC score	0.121081 (rank : 1293)	θ value	θ > 10 (rank : 1977)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	123
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NEDD4_HUMAN
NC score	0.120863 (rank : 1294)	θ value	8.40245e-06 (rank : 293)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	101
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

AKAP2_HUMAN
NC score	0.120828 (rank : 1295)	θ value	θ > 10 (rank : 1395)
Query Neighborhood Hits	1371	Target Neighborhood Hits	507	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MLL2_HUMAN
NC score	0.120804 (rank : 1296)	θ value	θ > 10 (rank : 1914)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1788	Shared Neighborhood Hits	385
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYO1C_MOUSE
NC score	0.120508 (rank : 1297)	θ value	θ > 10 (rank : 1938)
Query Neighborhood Hits	1371	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTI7, O08571, O08834, Q9QW54	Gene names	Myo1c
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMIb).

PTRF_HUMAN
NC score	0.120381 (rank : 1298)	θ value	θ > 10 (rank : 2053)
Query Neighborhood Hits	1371	Target Neighborhood Hits	153	Shared Neighborhood Hits	118
SwissProt Accessions	Q6NZI2, O00535, Q6GMY1, Q96H74, Q9BT85, Q9HAP4	Gene names	PTRF
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor (PTRF protein).

MYO1A_HUMAN
NC score	0.120340 (rank : 1299)	θ value	θ > 10 (rank : 1934)
Query Neighborhood Hits	1371	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UBC5, Q9UQD7	Gene names	MYO1A, MYHL
Domain Architecture
Description	Myosin Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC).

PTK6_MOUSE
NC score	0.120290 (rank : 1300)	θ value	0.00298849 (rank : 558)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1026	Shared Neighborhood Hits	233
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

TIM44_MOUSE
NC score	0.120184 (rank : 1301)	θ value	θ > 10 (rank : 2270)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	169
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

MYO1D_HUMAN
NC score	0.120173 (rank : 1302)	θ value	θ > 10 (rank : 1939)
Query Neighborhood Hits	1371	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	O94832, Q8NHP9	Gene names	MYO1D, KIAA0727
Domain Architecture
Description	Myosin Id.

MYO1C_HUMAN
NC score	0.120165 (rank : 1303)	θ value	θ > 10 (rank : 1937)
Query Neighborhood Hits	1371	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	O00159	Gene names	MYO1C
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMI-beta) (MMIb).

MYO1D_MOUSE
NC score	0.119981 (rank : 1304)	θ value	θ > 10 (rank : 1940)
Query Neighborhood Hits	1371	Target Neighborhood Hits	57	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SYD0, Q5SSK7, Q8BWY5	Gene names	Myo1d
Domain Architecture	No domain graphic available
Description	Myosin Id.

MICA1_MOUSE
NC score	0.119911 (rank : 1305)	θ value	θ > 10 (rank : 1909)
Query Neighborhood Hits	1371	Target Neighborhood Hits	400	Shared Neighborhood Hits	246
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

EMIL3_HUMAN
NC score	0.119852 (rank : 1306)	θ value	θ > 10 (rank : 1615)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

MYO1B_HUMAN
NC score	0.119564 (rank : 1307)	θ value	θ > 10 (rank : 1935)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

SYBU_HUMAN
NC score	0.119469 (rank : 1308)	θ value	θ > 10 (rank : 2222)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

MYO1B_MOUSE
NC score	0.119301 (rank : 1309)	θ value	θ > 10 (rank : 1936)
Query Neighborhood Hits	1371	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

RBNS5_MOUSE
NC score	0.119137 (rank : 1310)	θ value	θ > 10 (rank : 2067)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	149
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

SLY_MOUSE
NC score	0.118886 (rank : 1311)	θ value	1.06291 (rank : 1032)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SYT15_HUMAN
NC score	0.118750 (rank : 1312)	θ value	θ > 10 (rank : 2233)
Query Neighborhood Hits	1371	Target Neighborhood Hits	112	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

TXK_HUMAN
NC score	0.118398 (rank : 1313)	θ value	0.0113563 (rank : 637)
Query Neighborhood Hits	1371	Target Neighborhood Hits	971	Shared Neighborhood Hits	201
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

SFPQ_MOUSE
NC score	0.118237 (rank : 1314)	θ value	2.36792 (rank : 1159)
Query Neighborhood Hits	1371	Target Neighborhood Hits	958	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

WDR60_HUMAN
NC score	0.118025 (rank : 1315)	θ value	θ > 10 (rank : 2326)
Query Neighborhood Hits	1371	Target Neighborhood Hits	286	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

CCD50_MOUSE
NC score	0.117857 (rank : 1316)	θ value	θ > 10 (rank : 1482)
Query Neighborhood Hits	1371	Target Neighborhood Hits	172	Shared Neighborhood Hits	137
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

LCK_HUMAN
NC score	0.117770 (rank : 1317)	θ value	0.00175202 (rank : 518)
Query Neighborhood Hits	1371	Target Neighborhood Hits	987	Shared Neighborhood Hits	193
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

KIF17_HUMAN
NC score	0.117330 (rank : 1318)	θ value	5.27518 (rank : 1251)
Query Neighborhood Hits	1371	Target Neighborhood Hits	365	Shared Neighborhood Hits	237
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

LCK_MOUSE
NC score	0.117320 (rank : 1319)	θ value	0.00175202 (rank : 519)
Query Neighborhood Hits	1371	Target Neighborhood Hits	981	Shared Neighborhood Hits	191
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

K1H5_HUMAN
NC score	0.117274 (rank : 1320)	θ value	θ > 10 (rank : 1790)
Query Neighborhood Hits	1371	Target Neighborhood Hits	362	Shared Neighborhood Hits	243
SwissProt Accessions	Q92764, O76012, Q92651	Gene names	KRTHA5, HHA5, HKA5
Domain Architecture
Description	Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5).

MYO3A_HUMAN
NC score	0.117232 (rank : 1321)	θ value	θ > 10 (rank : 1941)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1033	Shared Neighborhood Hits	214
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

SYT12_MOUSE
NC score	0.117228 (rank : 1322)	θ value	θ > 10 (rank : 2228)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

TSKS_MOUSE
NC score	0.116866 (rank : 1323)	θ value	θ > 10 (rank : 2299)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	137
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

LIN1_HUMAN
NC score	0.116767 (rank : 1324)	θ value	0.62314 (rank : 966)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	127
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

CCD94_MOUSE
NC score	0.116726 (rank : 1325)	θ value	θ > 10 (rank : 1487)
Query Neighborhood Hits	1371	Target Neighborhood Hits	127	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D6J3	Gene names	Ccdc94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

NEDD4_MOUSE
NC score	0.116681 (rank : 1326)	θ value	1.87187e-05 (rank : 332)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	97
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

CHMP6_HUMAN
NC score	0.116637 (rank : 1327)	θ value	0.0736092 (rank : 749)
Query Neighborhood Hits	1371	Target Neighborhood Hits	92	Shared Neighborhood Hits	66
SwissProt Accessions	Q96FZ7, Q53FU4, Q9HAE8	Gene names	CHMP6, VPS20
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6) (Vacuolar protein sorting-associated protein 20) (hVps20).

GLU2B_MOUSE
NC score	0.116616 (rank : 1328)	θ value	θ > 10 (rank : 1698)
Query Neighborhood Hits	1371	Target Neighborhood Hits	357	Shared Neighborhood Hits	183
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

RT26_HUMAN
NC score	0.116510 (rank : 1329)	θ value	θ > 10 (rank : 2106)
Query Neighborhood Hits	1371	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYN8, Q96Q58	Gene names	MRPS26, RPMS13
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S26, mitochondrial precursor (MRP-S26) (MRP- S13).

PTK6_HUMAN
NC score	0.116458 (rank : 1330)	θ value	0.0431538 (rank : 716)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1020	Shared Neighborhood Hits	234
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

CSK_MOUSE
NC score	0.116272 (rank : 1331)	θ value	0.0148317 (rank : 642)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	209
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

SAKS1_MOUSE
NC score	0.116078 (rank : 1332)	θ value	θ > 10 (rank : 2113)
Query Neighborhood Hits	1371	Target Neighborhood Hits	208	Shared Neighborhood Hits	148
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

PA24E_HUMAN
NC score	0.115731 (rank : 1333)	θ value	0.0148317 (rank : 649)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

GLU2B_HUMAN
NC score	0.115722 (rank : 1334)	θ value	θ > 10 (rank : 1697)
Query Neighborhood Hits	1371	Target Neighborhood Hits	377	Shared Neighborhood Hits	181
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

SYT12_HUMAN
NC score	0.115621 (rank : 1335)	θ value	θ > 10 (rank : 2227)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

CSK_HUMAN
NC score	0.115585 (rank : 1336)	θ value	0.0148317 (rank : 641)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	209
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

DOCK1_HUMAN
NC score	0.115577 (rank : 1337)	θ value	0.125558 (rank : 808)
Query Neighborhood Hits	1371	Target Neighborhood Hits	191	Shared Neighborhood Hits	126
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

XL3B_MOUSE
NC score	0.115538 (rank : 1338)	θ value	θ > 10 (rank : 2337)
Query Neighborhood Hits	1371	Target Neighborhood Hits	146	Shared Neighborhood Hits	120
SwissProt Accessions	Q61806, Q61244	Gene names	Xlr3b
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A (XLR-related protein A12).

CENPK_MOUSE
NC score	0.115471 (rank : 1339)	θ value	θ > 10 (rank : 1503)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	118
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

SFPQ_HUMAN
NC score	0.115423 (rank : 1340)	θ value	2.36792 (rank : 1158)
Query Neighborhood Hits	1371	Target Neighborhood Hits	986	Shared Neighborhood Hits	283
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

KRHB4_MOUSE
NC score	0.115356 (rank : 1341)	θ value	θ > 10 (rank : 1848)
Query Neighborhood Hits	1371	Target Neighborhood Hits	344	Shared Neighborhood Hits	257
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

RFIP1_HUMAN
NC score	0.115233 (rank : 1342)	θ value	0.00035302 (rank : 449)
Query Neighborhood Hits	1371	Target Neighborhood Hits	236	Shared Neighborhood Hits	65
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

MPP5_HUMAN
NC score	0.115045 (rank : 1343)	θ value	0.00298849 (rank : 553)
Query Neighborhood Hits	1371	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

G45IP_MOUSE
NC score	0.114930 (rank : 1344)	θ value	θ > 10 (rank : 1684)
Query Neighborhood Hits	1371	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

BRD4_MOUSE
NC score	0.114898 (rank : 1345)	θ value	5.27518 (rank : 1236)
Query Neighborhood Hits	1371	Target Neighborhood Hits	845	Shared Neighborhood Hits	315
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MED4_MOUSE
NC score	0.114699 (rank : 1346)	θ value	0.21417 (rank : 850)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CQA5	Gene names	Med4, Vdrip
Domain Architecture	No domain graphic available
Description	Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4).

ITK_HUMAN
NC score	0.114628 (rank : 1347)	θ value	0.0193708 (rank : 664)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1016	Shared Neighborhood Hits	215
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

CCD94_HUMAN
NC score	0.114575 (rank : 1348)	θ value	θ > 10 (rank : 1486)
Query Neighborhood Hits	1371	Target Neighborhood Hits	139	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BW85, O75270, Q9H862, Q9NW16	Gene names	CCDC94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

ABL1_HUMAN
NC score	0.114567 (rank : 1349)	θ value	0.0148317 (rank : 638)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1220	Shared Neighborhood Hits	224
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

DTNA_HUMAN
NC score	0.114496 (rank : 1350)	θ value	θ > 10 (rank : 1597)
Query Neighborhood Hits	1371	Target Neighborhood Hits	295	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

UBXD2_MOUSE
NC score	0.114410 (rank : 1351)	θ value	1.06291 (rank : 1038)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	134
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

ABL1_MOUSE
NC score	0.114168 (rank : 1352)	θ value	0.0148317 (rank : 639)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1178	Shared Neighborhood Hits	220
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PRP40_MOUSE
NC score	0.114168 (rank : 1353)	θ value	θ > 10 (rank : 2043)
Query Neighborhood Hits	1371	Target Neighborhood Hits	447	Shared Neighborhood Hits	199
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

SYNG_HUMAN
NC score	0.114094 (rank : 1354)	θ value	0.00175202 (rank : 524)
Query Neighborhood Hits	1371	Target Neighborhood Hits	160	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

MPP5_MOUSE
NC score	0.114015 (rank : 1355)	θ value	0.00298849 (rank : 554)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

K1C19_HUMAN
NC score	0.113944 (rank : 1356)	θ value	θ > 10 (rank : 1784)
Query Neighborhood Hits	1371	Target Neighborhood Hits	320	Shared Neighborhood Hits	246
SwissProt Accessions	P08727, Q5XG83, Q6NW33, Q7L5M9, Q96A53, Q96FV1, Q9BYF9, Q9P1Y4	Gene names	KRT19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

MAT1_HUMAN
NC score	0.113912 (rank : 1357)	θ value	θ > 10 (rank : 1900)
Query Neighborhood Hits	1371	Target Neighborhood Hits	179	Shared Neighborhood Hits	127
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

KRHB4_HUMAN
NC score	0.113817 (rank : 1358)	θ value	θ > 10 (rank : 1847)
Query Neighborhood Hits	1371	Target Neighborhood Hits	352	Shared Neighborhood Hits	255
SwissProt Accessions	Q9NSB2	Gene names	KRTHB4
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4).

PKHF2_HUMAN
NC score	0.113756 (rank : 1359)	θ value	θ > 10 (rank : 2026)
Query Neighborhood Hits	1371	Target Neighborhood Hits	75	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

C8AP2_HUMAN
NC score	0.113589 (rank : 1360)	θ value	2.36792 (rank : 1123)
Query Neighborhood Hits	1371	Target Neighborhood Hits	548	Shared Neighborhood Hits	231
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

K1914_HUMAN
NC score	0.113462 (rank : 1361)	θ value	θ > 10 (rank : 1770)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	159
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

GBP5_MOUSE
NC score	0.113442 (rank : 1362)	θ value	θ > 10 (rank : 1692)
Query Neighborhood Hits	1371	Target Neighborhood Hits	254	Shared Neighborhood Hits	199
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

NUP62_HUMAN
NC score	0.113283 (rank : 1363)	θ value	θ > 10 (rank : 1992)
Query Neighborhood Hits	1371	Target Neighborhood Hits	195	Shared Neighborhood Hits	111
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

PKHF2_MOUSE
NC score	0.113078 (rank : 1364)	θ value	θ > 10 (rank : 2027)
Query Neighborhood Hits	1371	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

CF010_HUMAN
NC score	0.112719 (rank : 1365)	θ value	θ > 10 (rank : 1510)
Query Neighborhood Hits	1371	Target Neighborhood Hits	329	Shared Neighborhood Hits	139
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

SYT15_MOUSE
NC score	0.112624 (rank : 1366)	θ value	θ > 10 (rank : 2234)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYTL3_MOUSE
NC score	0.112554 (rank : 1367)	θ value	θ > 10 (rank : 2237)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

IQGA1_HUMAN
NC score	0.112363 (rank : 1368)	θ value	0.00390308 (rank : 567)
Query Neighborhood Hits	1371	Target Neighborhood Hits	250	Shared Neighborhood Hits	152
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

STX1B_HUMAN
NC score	0.111897 (rank : 1369)	θ value	θ > 10 (rank : 2208)
Query Neighborhood Hits	1371	Target Neighborhood Hits	252	Shared Neighborhood Hits	183
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

GOPC_MOUSE
NC score	0.111649 (rank : 1370)	θ value	0.62314 (rank : 962)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

FA50B_MOUSE
NC score	0.111423 (rank : 1371)	θ value	θ > 10 (rank : 1654)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	149
SwissProt Accessions	Q9WTJ8, Q80X84, Q9D993	Gene names	Fam50b, D0H6S2654E, X5l
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

TRAF5_HUMAN
NC score	0.111420 (rank : 1372)	θ value	3.0926 (rank : 1188)
Query Neighborhood Hits	1371	Target Neighborhood Hits	396	Shared Neighborhood Hits	220
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

STK31_HUMAN
NC score	0.110912 (rank : 1373)	θ value	θ > 10 (rank : 2199)
Query Neighborhood Hits	1371	Target Neighborhood Hits	570	Shared Neighborhood Hits	193
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

CD008_HUMAN
NC score	0.110661 (rank : 1374)	θ value	θ > 10 (rank : 1493)
Query Neighborhood Hits	1371	Target Neighborhood Hits	330	Shared Neighborhood Hits	155
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

TEKT3_HUMAN
NC score	0.110526 (rank : 1375)	θ value	θ > 10 (rank : 2263)
Query Neighborhood Hits	1371	Target Neighborhood Hits	123	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BXF9, Q8N5R5, Q96M48	Gene names	TEKT3
Domain Architecture
Description	Tektin-3.

SOS2_HUMAN
NC score	0.110394 (rank : 1376)	θ value	θ > 10 (rank : 2174)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	54
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

ABL2_HUMAN
NC score	0.110187 (rank : 1377)	θ value	0.0961366 (rank : 772)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1045	Shared Neighborhood Hits	198
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

KIFC2_MOUSE
NC score	0.110184 (rank : 1378)	θ value	θ > 10 (rank : 1829)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	141
SwissProt Accessions	O08672, O08613	Gene names	Kifc2
Domain Architecture
Description	Kinesin-like protein KIFC2.

MUTED_HUMAN
NC score	0.109940 (rank : 1379)	θ value	θ > 10 (rank : 1932)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TDH9, Q5THS1, Q68D56, Q8N5F9, Q9NU16	Gene names	MUTED
Domain Architecture	No domain graphic available
Description	Muted protein homolog.

KLC4_HUMAN
NC score	0.109933 (rank : 1380)	θ value	θ > 10 (rank : 1833)
Query Neighborhood Hits	1371	Target Neighborhood Hits	327	Shared Neighborhood Hits	229
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

XL3A_MOUSE
NC score	0.109739 (rank : 1381)	θ value	θ > 10 (rank : 2336)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	108
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

NOC3L_MOUSE
NC score	0.109457 (rank : 1382)	θ value	θ > 10 (rank : 1974)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	126
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

CNOT3_MOUSE
NC score	0.109456 (rank : 1383)	θ value	θ > 10 (rank : 1541)
Query Neighborhood Hits	1371	Target Neighborhood Hits	504	Shared Neighborhood Hits	186
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

NUP62_MOUSE
NC score	0.109285 (rank : 1384)	θ value	θ > 10 (rank : 1993)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	117
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

TAF4_HUMAN
NC score	0.108954 (rank : 1385)	θ value	0.0736092 (rank : 768)
Query Neighborhood Hits	1371	Target Neighborhood Hits	687	Shared Neighborhood Hits	193
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

KLC4_MOUSE
NC score	0.108935 (rank : 1386)	θ value	θ > 10 (rank : 1834)
Query Neighborhood Hits	1371	Target Neighborhood Hits	336	Shared Neighborhood Hits	234
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

ANGL3_MOUSE
NC score	0.108580 (rank : 1387)	θ value	0.00175202 (rank : 510)
Query Neighborhood Hits	1371	Target Neighborhood Hits	306	Shared Neighborhood Hits	221
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

NPHP3_MOUSE
NC score	0.108395 (rank : 1388)	θ value	θ > 10 (rank : 1980)
Query Neighborhood Hits	1371	Target Neighborhood Hits	335	Shared Neighborhood Hits	218
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

SPC24_MOUSE
NC score	0.108392 (rank : 1389)	θ value	θ > 10 (rank : 2178)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D083, Q3TIF5, Q8CD13	Gene names	Spbc24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24.

PKHF1_HUMAN
NC score	0.108337 (rank : 1390)	θ value	θ > 10 (rank : 2024)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

STK31_MOUSE
NC score	0.108303 (rank : 1391)	θ value	θ > 10 (rank : 2200)
Query Neighborhood Hits	1371	Target Neighborhood Hits	474	Shared Neighborhood Hits	167
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

MPP2_MOUSE
NC score	0.108299 (rank : 1392)	θ value	0.0736092 (rank : 761)
Query Neighborhood Hits	1371	Target Neighborhood Hits	189	Shared Neighborhood Hits	88
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

RUSC2_MOUSE
NC score	0.108156 (rank : 1393)	θ value	0.0563607 (rank : 735)
Query Neighborhood Hits	1371	Target Neighborhood Hits	305	Shared Neighborhood Hits	87
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

ITK_MOUSE
NC score	0.108155 (rank : 1394)	θ value	0.0961366 (rank : 785)
Query Neighborhood Hits	1371	Target Neighborhood Hits	985	Shared Neighborhood Hits	196
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

CD2L1_MOUSE
NC score	0.108102 (rank : 1395)	θ value	0.813845 (rank : 978)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1463	Shared Neighborhood Hits	441
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

GO45_MOUSE
NC score	0.107923 (rank : 1396)	θ value	θ > 10 (rank : 1701)
Query Neighborhood Hits	1371	Target Neighborhood Hits	139	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R2X8, Q3TJC4, Q8C0U6, Q9DAV7	Gene names	Blzf1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1).

STABP_MOUSE
NC score	0.107894 (rank : 1397)	θ value	0.0961366 (rank : 792)
Query Neighborhood Hits	1371	Target Neighborhood Hits	191	Shared Neighborhood Hits	144
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

MYPT1_HUMAN
NC score	0.107683 (rank : 1398)	θ value	θ > 10 (rank : 1950)
Query Neighborhood Hits	1371	Target Neighborhood Hits	723	Shared Neighborhood Hits	316
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

CS029_MOUSE
NC score	0.107631 (rank : 1399)	θ value	θ > 10 (rank : 1549)
Query Neighborhood Hits	1371	Target Neighborhood Hits	201	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

WWC3_HUMAN
NC score	0.107616 (rank : 1400)	θ value	θ > 10 (rank : 2334)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	124
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

RN168_MOUSE
NC score	0.107602 (rank : 1401)	θ value	θ > 10 (rank : 2094)
Query Neighborhood Hits	1371	Target Neighborhood Hits	440	Shared Neighborhood Hits	178
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

MPP2_HUMAN
NC score	0.107559 (rank : 1402)	θ value	0.0736092 (rank : 760)
Query Neighborhood Hits	1371	Target Neighborhood Hits	173	Shared Neighborhood Hits	87
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

NIPBL_HUMAN
NC score	0.107506 (rank : 1403)	θ value	1.81305 (rank : 1104)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1311	Shared Neighborhood Hits	337
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PTRF_MOUSE
NC score	0.107238 (rank : 1404)	θ value	θ > 10 (rank : 2054)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	117
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

FOXP2_MOUSE
NC score	0.107230 (rank : 1405)	θ value	2.36792 (rank : 1137)
Query Neighborhood Hits	1371	Target Neighborhood Hits	366	Shared Neighborhood Hits	216
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

SYCP3_MOUSE
NC score	0.107176 (rank : 1406)	θ value	θ > 10 (rank : 2226)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	118
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

TBCD4_HUMAN
NC score	0.107089 (rank : 1407)	θ value	θ > 10 (rank : 2256)
Query Neighborhood Hits	1371	Target Neighborhood Hits	357	Shared Neighborhood Hits	234
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

PA24A_MOUSE
NC score	0.106948 (rank : 1408)	θ value	0.0961366 (rank : 788)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

SAKS1_HUMAN
NC score	0.106923 (rank : 1409)	θ value	θ > 10 (rank : 2112)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	136
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

HDAC5_HUMAN
NC score	0.106911 (rank : 1410)	θ value	θ > 10 (rank : 1715)
Query Neighborhood Hits	1371	Target Neighborhood Hits	353	Shared Neighborhood Hits	244
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

DTNB_HUMAN
NC score	0.106899 (rank : 1411)	θ value	θ > 10 (rank : 1599)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	188
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

STX3_HUMAN
NC score	0.106738 (rank : 1412)	θ value	0.0961366 (rank : 795)
Query Neighborhood Hits	1371	Target Neighborhood Hits	211	Shared Neighborhood Hits	160
SwissProt Accessions	Q13277, O43750, O43751, Q15360	Gene names	STX3, STX3A
Domain Architecture
Description	Syntaxin-3.

PKHF1_MOUSE
NC score	0.106517 (rank : 1413)	θ value	θ > 10 (rank : 2025)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

UVRAG_HUMAN
NC score	0.106449 (rank : 1414)	θ value	θ > 10 (rank : 2320)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	120
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

MYO3B_HUMAN
NC score	0.106365 (rank : 1415)	θ value	θ > 10 (rank : 1943)
Query Neighborhood Hits	1371	Target Neighborhood Hits	923	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

KIFC2_HUMAN
NC score	0.106314 (rank : 1416)	θ value	θ > 10 (rank : 1828)
Query Neighborhood Hits	1371	Target Neighborhood Hits	237	Shared Neighborhood Hits	139
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

TAOK2_HUMAN
NC score	0.106103 (rank : 1417)	θ value	1.06291 (rank : 1036)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1172	Shared Neighborhood Hits	336
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

ZN365_HUMAN
NC score	0.106030 (rank : 1418)	θ value	8.99809 (rank : 1370)
Query Neighborhood Hits	1371	Target Neighborhood Hits	145	Shared Neighborhood Hits	109
SwissProt Accessions	Q70YC5, O94930, Q5HYE6, Q68SG8, Q6NSK2, Q6P9D4, Q70YC6, Q70YC7	Gene names	ZNF365, KIAA0844
Domain Architecture	No domain graphic available
Description	Protein ZNF365.

PFD6_HUMAN
NC score	0.106011 (rank : 1419)	θ value	θ > 10 (rank : 2017)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	99
SwissProt Accessions	O15212	Gene names	PFDN6, HKE2, PFD6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

GIMA4_HUMAN
NC score	0.105672 (rank : 1420)	θ value	6.88961 (rank : 1297)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NUV9	Gene names	GIMAP4, IAN1, IMAP4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1).

CD2L1_HUMAN
NC score	0.105521 (rank : 1421)	θ value	0.47712 (rank : 934)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1467	Shared Neighborhood Hits	439
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

DTNA_MOUSE
NC score	0.105403 (rank : 1422)	θ value	θ > 10 (rank : 1598)
Query Neighborhood Hits	1371	Target Neighborhood Hits	264	Shared Neighborhood Hits	184
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

PKHA6_HUMAN
NC score	0.105302 (rank : 1423)	θ value	θ > 10 (rank : 2022)
Query Neighborhood Hits	1371	Target Neighborhood Hits	556	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MYO3A_MOUSE
NC score	0.105145 (rank : 1424)	θ value	θ > 10 (rank : 1942)
Query Neighborhood Hits	1371	Target Neighborhood Hits	902	Shared Neighborhood Hits	142
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

CL025_HUMAN
NC score	0.105126 (rank : 1425)	θ value	θ > 10 (rank : 1528)
Query Neighborhood Hits	1371	Target Neighborhood Hits	179	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

STX3_MOUSE
NC score	0.104818 (rank : 1426)	θ value	0.0961366 (rank : 796)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	162
SwissProt Accessions	Q64704	Gene names	Stx3, Stx3a
Domain Architecture
Description	Syntaxin-3.

PA24E_MOUSE
NC score	0.104710 (rank : 1427)	θ value	1.38821 (rank : 1062)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

DAAM2_HUMAN
NC score	0.104258 (rank : 1428)	θ value	4.03905 (rank : 1201)
Query Neighborhood Hits	1371	Target Neighborhood Hits	350	Shared Neighborhood Hits	232
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

APOB_HUMAN
NC score	0.104255 (rank : 1429)	θ value	θ > 10 (rank : 1421)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	121
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

RBBP6_HUMAN
NC score	0.104157 (rank : 1430)	θ value	θ > 10 (rank : 2064)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1135	Shared Neighborhood Hits	267
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

MPP4_MOUSE
NC score	0.103707 (rank : 1431)	θ value	0.813845 (rank : 985)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

STX1A_HUMAN
NC score	0.103699 (rank : 1432)	θ value	θ > 10 (rank : 2206)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	196
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

ACTN4_MOUSE
NC score	0.103667 (rank : 1433)	θ value	θ > 10 (rank : 1390)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	174
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

MINT_MOUSE
NC score	0.103665 (rank : 1434)	θ value	0.00869519 (rank : 612)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1514	Shared Neighborhood Hits	298
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

AKAP2_MOUSE
NC score	0.103259 (rank : 1435)	θ value	4.03905 (rank : 1193)
Query Neighborhood Hits	1371	Target Neighborhood Hits	385	Shared Neighborhood Hits	161
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

KPCB_MOUSE
NC score	0.103197 (rank : 1436)	θ value	4.1701e-05 (rank : 360)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1117	Shared Neighborhood Hits	187
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
NC score	0.102891 (rank : 1437)	θ value	4.1701e-05 (rank : 359)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1121	Shared Neighborhood Hits	187
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

STX1A_MOUSE
NC score	0.102865 (rank : 1438)	θ value	θ > 10 (rank : 2207)
Query Neighborhood Hits	1371	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

CT077_HUMAN
NC score	0.102503 (rank : 1439)	θ value	θ > 10 (rank : 1551)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

KPCA_HUMAN
NC score	0.102503 (rank : 1440)	θ value	2.44474e-05 (rank : 342)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1070	Shared Neighborhood Hits	190
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

LAMA1_MOUSE
NC score	0.102382 (rank : 1441)	θ value	1.81305 (rank : 1095)
Query Neighborhood Hits	1371	Target Neighborhood Hits	838	Shared Neighborhood Hits	280
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

SYT13_HUMAN
NC score	0.102187 (rank : 1442)	θ value	θ > 10 (rank : 2229)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	55
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

KPCG_HUMAN
NC score	0.102179 (rank : 1443)	θ value	0.000786445 (rank : 484)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1126	Shared Neighborhood Hits	193
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

FOXP2_HUMAN
NC score	0.102171 (rank : 1444)	θ value	θ > 10 (rank : 1678)
Query Neighborhood Hits	1371	Target Neighborhood Hits	366	Shared Neighborhood Hits	216
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

SH21B_MOUSE
NC score	0.102070 (rank : 1445)	θ value	θ > 10 (rank : 2137)
Query Neighborhood Hits	1371	Target Neighborhood Hits	101	Shared Neighborhood Hits	50
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SLY_HUMAN
NC score	0.101921 (rank : 1446)	θ value	1.81305 (rank : 1109)
Query Neighborhood Hits	1371	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

MAML2_HUMAN
NC score	0.101734 (rank : 1447)	θ value	θ > 10 (rank : 1898)
Query Neighborhood Hits	1371	Target Neighborhood Hits	360	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MYPT2_HUMAN
NC score	0.101606 (rank : 1448)	θ value	θ > 10 (rank : 1952)
Query Neighborhood Hits	1371	Target Neighborhood Hits	707	Shared Neighborhood Hits	317
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

HDAC9_MOUSE
NC score	0.101581 (rank : 1449)	θ value	θ > 10 (rank : 1718)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	135
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

PA24B_HUMAN
NC score	0.101372 (rank : 1450)	θ value	1.06291 (rank : 1023)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

KPCG_MOUSE
NC score	0.101338 (rank : 1451)	θ value	0.00228821 (rank : 533)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1123	Shared Neighborhood Hits	192
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

CNOT3_HUMAN
NC score	0.101320 (rank : 1452)	θ value	θ > 10 (rank : 1540)
Query Neighborhood Hits	1371	Target Neighborhood Hits	425	Shared Neighborhood Hits	164
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

RBNS5_HUMAN
NC score	0.101189 (rank : 1453)	θ value	θ > 10 (rank : 2066)
Query Neighborhood Hits	1371	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

MIPO1_MOUSE
NC score	0.101148 (rank : 1454)	θ value	θ > 10 (rank : 1911)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	86
SwissProt Accessions	Q9D9F8	Gene names	Mipol1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein homolog.

CT077_MOUSE
NC score	0.101075 (rank : 1455)	θ value	θ > 10 (rank : 1552)
Query Neighborhood Hits	1371	Target Neighborhood Hits	122	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CSU0, Q3U8H1, Q3UGH1, Q3USX3, Q6GTJ6	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf77 homolog.

BRD4_HUMAN
NC score	0.101052 (rank : 1456)	θ value	5.27518 (rank : 1235)
Query Neighborhood Hits	1371	Target Neighborhood Hits	851	Shared Neighborhood Hits	292
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

K1377_HUMAN
NC score	0.100724 (rank : 1457)	θ value	θ > 10 (rank : 1769)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	101
SwissProt Accessions	Q9P2H0, Q4G0U6	Gene names	KIAA1377
Domain Architecture	No domain graphic available
Description	Protein KIAA1377.

KPCA_MOUSE
NC score	0.100664 (rank : 1458)	θ value	9.29e-05 (rank : 389)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1067	Shared Neighborhood Hits	190
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KI18A_MOUSE
NC score	0.100452 (rank : 1459)	θ value	4.03905 (rank : 1210)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	142
SwissProt Accessions	Q91WD7, Q3TP77, Q8BLL1	Gene names	Kif18a
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

SRCA_MOUSE
NC score	0.100357 (rank : 1460)	θ value	θ > 10 (rank : 2185)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

ACTN4_HUMAN
NC score	0.100310 (rank : 1461)	θ value	θ > 10 (rank : 1389)
Query Neighborhood Hits	1371	Target Neighborhood Hits	279	Shared Neighborhood Hits	174
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

CHMP6_MOUSE
NC score	0.100176 (rank : 1462)	θ value	0.0736092 (rank : 750)
Query Neighborhood Hits	1371	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	P0C0A3	Gene names	Chmp6
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6).

NARGL_HUMAN
NC score	0.100127 (rank : 1463)	θ value	0.62314 (rank : 970)
Query Neighborhood Hits	1371	Target Neighborhood Hits	222	Shared Neighborhood Hits	148
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

HDAC4_HUMAN
NC score	0.100000 (rank : 1464)	θ value	2.36792 (rank : 1138)
Query Neighborhood Hits	1371	Target Neighborhood Hits	390	Shared Neighborhood Hits	247
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

SYT13_MOUSE
NC score	0.099839 (rank : 1465)	θ value	θ > 10 (rank : 2230)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

MYT1L_HUMAN
NC score	0.099389 (rank : 1466)	θ value	θ > 10 (rank : 1956)
Query Neighborhood Hits	1371	Target Neighborhood Hits	471	Shared Neighborhood Hits	244
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

KRHB5_HUMAN
NC score	0.099379 (rank : 1467)	θ value	θ > 10 (rank : 1849)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	235
SwissProt Accessions	P78386, Q9NSB1	Gene names	KRTHB5
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

DTNB_MOUSE
NC score	0.098944 (rank : 1468)	θ value	5.27518 (rank : 1243)
Query Neighborhood Hits	1371	Target Neighborhood Hits	263	Shared Neighborhood Hits	168
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

PA24A_HUMAN
NC score	0.098886 (rank : 1469)	θ value	0.813845 (rank : 991)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

ATD3A_HUMAN
NC score	0.098757 (rank : 1470)	θ value	θ > 10 (rank : 1430)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

PELP1_HUMAN
NC score	0.098617 (rank : 1471)	θ value	θ > 10 (rank : 2012)
Query Neighborhood Hits	1371	Target Neighborhood Hits	596	Shared Neighborhood Hits	218
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

UT14C_HUMAN
NC score	0.098478 (rank : 1472)	θ value	θ > 10 (rank : 2319)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	137
SwissProt Accessions	Q5TAP6, Q5FWG3, Q92555	Gene names	UTP14C, KIAA0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog C.

SRCA_HUMAN
NC score	0.098465 (rank : 1473)	θ value	θ > 10 (rank : 2184)
Query Neighborhood Hits	1371	Target Neighborhood Hits	380	Shared Neighborhood Hits	65
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

MORC4_MOUSE
NC score	0.098431 (rank : 1474)	θ value	θ > 10 (rank : 1919)
Query Neighborhood Hits	1371	Target Neighborhood Hits	235	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

UTP11_HUMAN
NC score	0.098149 (rank : 1475)	θ value	0.0563607 (rank : 742)
Query Neighborhood Hits	1371	Target Neighborhood Hits	99	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y3A2, Q5VT93, Q9BS98, Q9NS31	Gene names	UTP11L
Domain Architecture
Description	Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA- associated protein 11) (UTP11-like protein).

FUT8_MOUSE
NC score	0.097950 (rank : 1476)	θ value	θ > 10 (rank : 1680)
Query Neighborhood Hits	1371	Target Neighborhood Hits	115	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

ANGL3_HUMAN
NC score	0.097837 (rank : 1477)	θ value	0.0148317 (rank : 640)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

APC_HUMAN
NC score	0.097795 (rank : 1478)	θ value	θ > 10 (rank : 1414)
Query Neighborhood Hits	1371	Target Neighborhood Hits	603	Shared Neighborhood Hits	213
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PA24F_MOUSE
NC score	0.097555 (rank : 1479)	θ value	0.0113563 (rank : 631)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	68
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

TXND2_MOUSE
NC score	0.097048 (rank : 1480)	θ value	θ > 10 (rank : 2304)
Query Neighborhood Hits	1371	Target Neighborhood Hits	828	Shared Neighborhood Hits	240
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

S6OS1_HUMAN
NC score	0.097014 (rank : 1481)	θ value	θ > 10 (rank : 2109)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N1H7	Gene names	SIX6OS1, C14orf39
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

DHX16_HUMAN
NC score	0.096837 (rank : 1482)	θ value	θ > 10 (rank : 1583)
Query Neighborhood Hits	1371	Target Neighborhood Hits	356	Shared Neighborhood Hits	233
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

STX18_HUMAN
NC score	0.096775 (rank : 1483)	θ value	θ > 10 (rank : 2205)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	127
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

FLOT1_HUMAN
NC score	0.096646 (rank : 1484)	θ value	θ > 10 (rank : 1672)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	113
SwissProt Accessions	O75955, Q969J8, Q9UHW1, Q9UNV8	Gene names	FLOT1
Domain Architecture
Description	Flotillin-1.

FA50B_HUMAN
NC score	0.096367 (rank : 1485)	θ value	θ > 10 (rank : 1653)
Query Neighborhood Hits	1371	Target Neighborhood Hits	130	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y247	Gene names	FAM50B, X5L
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

SH21B_HUMAN
NC score	0.096202 (rank : 1486)	θ value	θ > 10 (rank : 2136)
Query Neighborhood Hits	1371	Target Neighborhood Hits	101	Shared Neighborhood Hits	51
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

LAMC2_MOUSE
NC score	0.096033 (rank : 1487)	θ value	θ > 10 (rank : 1869)
Query Neighborhood Hits	1371	Target Neighborhood Hits	614	Shared Neighborhood Hits	208
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

SYT14_MOUSE
NC score	0.095988 (rank : 1488)	θ value	θ > 10 (rank : 2232)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

MPP4_HUMAN
NC score	0.095924 (rank : 1489)	θ value	4.03905 (rank : 1214)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	90
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

DAAM2_MOUSE
NC score	0.095788 (rank : 1490)	θ value	θ > 10 (rank : 1565)
Query Neighborhood Hits	1371	Target Neighborhood Hits	371	Shared Neighborhood Hits	225
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

CD2L2_HUMAN
NC score	0.095599 (rank : 1491)	θ value	4.03905 (rank : 1199)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1439	Shared Neighborhood Hits	429
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

HTSF1_HUMAN
NC score	0.095553 (rank : 1492)	θ value	θ > 10 (rank : 1732)
Query Neighborhood Hits	1371	Target Neighborhood Hits	408	Shared Neighborhood Hits	151
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

BPTF_HUMAN
NC score	0.095335 (rank : 1493)	θ value	θ > 10 (rank : 1457)
Query Neighborhood Hits	1371	Target Neighborhood Hits	786	Shared Neighborhood Hits	228
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SHE_MOUSE
NC score	0.095310 (rank : 1494)	θ value	θ > 10 (rank : 2153)
Query Neighborhood Hits	1371	Target Neighborhood Hits	169	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

CIR_HUMAN
NC score	0.095273 (rank : 1495)	θ value	θ > 10 (rank : 1522)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	116
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

MYT1L_MOUSE
NC score	0.095071 (rank : 1496)	θ value	θ > 10 (rank : 1957)
Query Neighborhood Hits	1371	Target Neighborhood Hits	461	Shared Neighborhood Hits	237
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

UN84B_HUMAN
NC score	0.094919 (rank : 1497)	θ value	θ > 10 (rank : 2312)
Query Neighborhood Hits	1371	Target Neighborhood Hits	172	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UH99, O75156, Q6B4H1, Q7Z3E3	Gene names	UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2
Domain Architecture	No domain graphic available
Description	Sad1/unc-84-like protein 2 (Rab5-interacting protein) (Rab5IP).

CHIN_MOUSE
NC score	0.094906 (rank : 1498)	θ value	θ > 10 (rank : 1516)
Query Neighborhood Hits	1371	Target Neighborhood Hits	229	Shared Neighborhood Hits	83
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

OXR1_MOUSE
NC score	0.094874 (rank : 1499)	θ value	θ > 10 (rank : 2000)
Query Neighborhood Hits	1371	Target Neighborhood Hits	516	Shared Neighborhood Hits	190
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

DYXC1_HUMAN
NC score	0.094639 (rank : 1500)	θ value	0.125558 (rank : 809)
Query Neighborhood Hits	1371	Target Neighborhood Hits	261	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

PDCD7_MOUSE
NC score	0.094294 (rank : 1501)	θ value	θ > 10 (rank : 2011)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	110
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

TRI62_HUMAN
NC score	0.094216 (rank : 1502)	θ value	0.47712 (rank : 955)
Query Neighborhood Hits	1371	Target Neighborhood Hits	584	Shared Neighborhood Hits	303
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

KI18A_HUMAN
NC score	0.094193 (rank : 1503)	θ value	θ > 10 (rank : 1806)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	113
SwissProt Accessions	Q8NI77, Q86VS5, Q9H0F3	Gene names	KIF18A
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

CE110_HUMAN
NC score	0.094035 (rank : 1504)	θ value	θ > 10 (rank : 1501)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	147
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

ACTN2_HUMAN
NC score	0.093896 (rank : 1505)	θ value	θ > 10 (rank : 1386)
Query Neighborhood Hits	1371	Target Neighborhood Hits	295	Shared Neighborhood Hits	178
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

HSF2B_HUMAN
NC score	0.093769 (rank : 1506)	θ value	θ > 10 (rank : 1726)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	82
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

CCDC5_MOUSE
NC score	0.093721 (rank : 1507)	θ value	θ > 10 (rank : 1490)
Query Neighborhood Hits	1371	Target Neighborhood Hits	91	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BHX1, Q3UIH2, Q8R1M1	Gene names	Ccdc5
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5.

SYT14_HUMAN
NC score	0.093620 (rank : 1508)	θ value	θ > 10 (rank : 2231)
Query Neighborhood Hits	1371	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SRMS_MOUSE
NC score	0.093576 (rank : 1509)	θ value	1.38821 (rank : 1069)
Query Neighborhood Hits	1371	Target Neighborhood Hits	964	Shared Neighborhood Hits	173
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

DRP2_HUMAN
NC score	0.093530 (rank : 1510)	θ value	θ > 10 (rank : 1594)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	127
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

SEPT8_HUMAN
NC score	0.093245 (rank : 1511)	θ value	θ > 10 (rank : 2126)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	217
SwissProt Accessions	Q92599, Q8IX36, Q8IX37, Q9BVB3	Gene names	SEPT8, KIAA0202
Domain Architecture
Description	Septin-8.

KRHB5_MOUSE
NC score	0.093021 (rank : 1512)	θ value	θ > 10 (rank : 1850)
Query Neighborhood Hits	1371	Target Neighborhood Hits	294	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

TLK2_MOUSE
NC score	0.093014 (rank : 1513)	θ value	1.38821 (rank : 1071)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1088	Shared Neighborhood Hits	325
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

UN84A_HUMAN
NC score	0.092996 (rank : 1514)	θ value	θ > 10 (rank : 2311)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	148
SwissProt Accessions	O94901, Q96CZ7, Q9HA14, Q9UH98	Gene names	UNC84A, KIAA0810, SUN1
Domain Architecture	No domain graphic available
Description	Sad1/unc-84 protein-like 1 (Unc-84 homolog A).

ACTN3_MOUSE
NC score	0.092925 (rank : 1515)	θ value	0.0736092 (rank : 743)
Query Neighborhood Hits	1371	Target Neighborhood Hits	265	Shared Neighborhood Hits	159
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ESCO1_HUMAN
NC score	0.092875 (rank : 1516)	θ value	0.365318 (rank : 906)
Query Neighborhood Hits	1371	Target Neighborhood Hits	361	Shared Neighborhood Hits	153
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

GEMI_MOUSE
NC score	0.092789 (rank : 1517)	θ value	θ > 10 (rank : 1696)
Query Neighborhood Hits	1371	Target Neighborhood Hits	163	Shared Neighborhood Hits	124
SwissProt Accessions	O88513	Gene names	Gmnn
Domain Architecture
Description	Geminin.

RASA2_MOUSE
NC score	0.092764 (rank : 1518)	θ value	θ > 10 (rank : 2060)
Query Neighborhood Hits	1371	Target Neighborhood Hits	159	Shared Neighborhood Hits	82
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

KIF1A_HUMAN
NC score	0.092733 (rank : 1519)	θ value	4.03905 (rank : 1211)
Query Neighborhood Hits	1371	Target Neighborhood Hits	240	Shared Neighborhood Hits	150
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

CHIN_HUMAN
NC score	0.092732 (rank : 1520)	θ value	θ > 10 (rank : 1515)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	80
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

FBX28_HUMAN
NC score	0.092645 (rank : 1521)	θ value	θ > 10 (rank : 1664)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NVF7, O75070	Gene names	FBXO28, KIAA0483
Domain Architecture	No domain graphic available
Description	F-box only protein 28.

DAB2P_MOUSE
NC score	0.092635 (rank : 1522)	θ value	θ > 10 (rank : 1567)
Query Neighborhood Hits	1371	Target Neighborhood Hits	284	Shared Neighborhood Hits	177
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

CCDC3_MOUSE
NC score	0.092598 (rank : 1523)	θ value	θ > 10 (rank : 1489)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	103
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

GEMI_HUMAN
NC score	0.092424 (rank : 1524)	θ value	θ > 10 (rank : 1695)
Query Neighborhood Hits	1371	Target Neighborhood Hits	192	Shared Neighborhood Hits	134
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

KIF1A_MOUSE
NC score	0.092222 (rank : 1525)	θ value	4.03905 (rank : 1212)
Query Neighborhood Hits	1371	Target Neighborhood Hits	239	Shared Neighborhood Hits	146
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

SEP11_MOUSE
NC score	0.092084 (rank : 1526)	θ value	0.279714 (rank : 888)
Query Neighborhood Hits	1371	Target Neighborhood Hits	300	Shared Neighborhood Hits	204
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

MPP3_MOUSE
NC score	0.092084 (rank : 1527)	θ value	0.0113563 (rank : 628)
Query Neighborhood Hits	1371	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP3_HUMAN
NC score	0.091867 (rank : 1528)	θ value	0.0193708 (rank : 668)
Query Neighborhood Hits	1371	Target Neighborhood Hits	171	Shared Neighborhood Hits	61
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

ATRX_MOUSE
NC score	0.091545 (rank : 1529)	θ value	θ > 10 (rank : 1434)
Query Neighborhood Hits	1371	Target Neighborhood Hits	682	Shared Neighborhood Hits	256
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SHE_HUMAN
NC score	0.091461 (rank : 1530)	θ value	θ > 10 (rank : 2152)
Query Neighborhood Hits	1371	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SYCP2_HUMAN
NC score	0.091298 (rank : 1531)	θ value	θ > 10 (rank : 2224)
Query Neighborhood Hits	1371	Target Neighborhood Hits	230	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

SNIP_HUMAN
NC score	0.091074 (rank : 1532)	θ value	θ > 10 (rank : 2161)
Query Neighborhood Hits	1371	Target Neighborhood Hits	313	Shared Neighborhood Hits	156
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

AMRP_HUMAN
NC score	0.090979 (rank : 1533)	θ value	θ > 10 (rank : 1401)
Query Neighborhood Hits	1371	Target Neighborhood Hits	126	Shared Neighborhood Hits	101
SwissProt Accessions	P30533	Gene names	LRPAP1, A2MRAP
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP).

CHIO_HUMAN
NC score	0.090887 (rank : 1534)	θ value	θ > 10 (rank : 1517)
Query Neighborhood Hits	1371	Target Neighborhood Hits	220	Shared Neighborhood Hits	80
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

DYH5_HUMAN
NC score	0.090706 (rank : 1535)	θ value	θ > 10 (rank : 1602)
Query Neighborhood Hits	1371	Target Neighborhood Hits	323	Shared Neighborhood Hits	207
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

GBP5_HUMAN
NC score	0.090605 (rank : 1536)	θ value	θ > 10 (rank : 1691)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	152
SwissProt Accessions	Q96PP8	Gene names	GBP5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (GBP-TA antigen).

NOE1_HUMAN
NC score	0.090314 (rank : 1537)	θ value	θ > 10 (rank : 1975)
Query Neighborhood Hits	1371	Target Neighborhood Hits	266	Shared Neighborhood Hits	204
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

TRI39_MOUSE
NC score	0.090202 (rank : 1538)	θ value	5.27518 (rank : 1272)
Query Neighborhood Hits	1371	Target Neighborhood Hits	691	Shared Neighborhood Hits	336
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

ANLN_MOUSE
NC score	0.090065 (rank : 1539)	θ value	5.27518 (rank : 1231)
Query Neighborhood Hits	1371	Target Neighborhood Hits	297	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

NPHP3_HUMAN
NC score	0.089944 (rank : 1540)	θ value	θ > 10 (rank : 1979)
Query Neighborhood Hits	1371	Target Neighborhood Hits	304	Shared Neighborhood Hits	194
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

NSBP1_HUMAN
NC score	0.089854 (rank : 1541)	θ value	θ > 10 (rank : 1985)
Query Neighborhood Hits	1371	Target Neighborhood Hits	251	Shared Neighborhood Hits	100
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

CCD16_MOUSE
NC score	0.089706 (rank : 1542)	θ value	θ > 10 (rank : 1476)
Query Neighborhood Hits	1371	Target Neighborhood Hits	218	Shared Neighborhood Hits	124
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

RASA3_HUMAN
NC score	0.089558 (rank : 1543)	θ value	θ > 10 (rank : 2061)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	89
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

DAB2P_HUMAN
NC score	0.089484 (rank : 1544)	θ value	θ > 10 (rank : 1566)
Query Neighborhood Hits	1371	Target Neighborhood Hits	303	Shared Neighborhood Hits	178
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

BIN3_HUMAN
NC score	0.089391 (rank : 1545)	θ value	θ > 10 (rank : 1451)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQY0, Q9BVG2, Q9NVY9	Gene names	BIN3
Domain Architecture
Description	Bridging integrator 3.

SEP11_HUMAN
NC score	0.089369 (rank : 1546)	θ value	0.365318 (rank : 923)
Query Neighborhood Hits	1371	Target Neighborhood Hits	296	Shared Neighborhood Hits	202
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

UT14A_HUMAN
NC score	0.089325 (rank : 1547)	θ value	θ > 10 (rank : 2316)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

TTC1_HUMAN
NC score	0.089281 (rank : 1548)	θ value	0.813845 (rank : 1000)
Query Neighborhood Hits	1371	Target Neighborhood Hits	417	Shared Neighborhood Hits	184
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TEX14_HUMAN
NC score	0.089168 (rank : 1549)	θ value	θ > 10 (rank : 2265)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1103	Shared Neighborhood Hits	221
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

MDC1_HUMAN
NC score	0.089042 (rank : 1550)	θ value	0.0113563 (rank : 627)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1446	Shared Neighborhood Hits	280
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TEKT3_MOUSE
NC score	0.089004 (rank : 1551)	θ value	θ > 10 (rank : 2264)
Query Neighborhood Hits	1371	Target Neighborhood Hits	123	Shared Neighborhood Hits	101
SwissProt Accessions	Q6X6Z7	Gene names	Tekt3
Domain Architecture	No domain graphic available
Description	Tektin-3.

TRI17_MOUSE
NC score	0.088808 (rank : 1552)	θ value	θ > 10 (rank : 2291)
Query Neighborhood Hits	1371	Target Neighborhood Hits	620	Shared Neighborhood Hits	323
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

RASA2_HUMAN
NC score	0.088777 (rank : 1553)	θ value	θ > 10 (rank : 2059)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

PA24F_HUMAN
NC score	0.088734 (rank : 1554)	θ value	0.0563607 (rank : 733)
Query Neighborhood Hits	1371	Target Neighborhood Hits	78	Shared Neighborhood Hits	68
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PLDN_HUMAN
NC score	0.088417 (rank : 1555)	θ value	8.99809 (rank : 1353)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UL45	Gene names	PLDN, PA
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein).

TRI39_HUMAN
NC score	0.088300 (rank : 1556)	θ value	5.27518 (rank : 1271)
Query Neighborhood Hits	1371	Target Neighborhood Hits	693	Shared Neighborhood Hits	336
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

SHB_MOUSE
NC score	0.088299 (rank : 1557)	θ value	θ > 10 (rank : 2143)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

ACTN2_MOUSE
NC score	0.088186 (rank : 1558)	θ value	θ > 10 (rank : 1387)
Query Neighborhood Hits	1371	Target Neighborhood Hits	287	Shared Neighborhood Hits	176
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

DYH5_MOUSE
NC score	0.087771 (rank : 1559)	θ value	θ > 10 (rank : 1603)
Query Neighborhood Hits	1371	Target Neighborhood Hits	286	Shared Neighborhood Hits	185
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

NOE1_MOUSE
NC score	0.087630 (rank : 1560)	θ value	θ > 10 (rank : 1976)
Query Neighborhood Hits	1371	Target Neighborhood Hits	258	Shared Neighborhood Hits	203
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

CTGE3_HUMAN
NC score	0.087543 (rank : 1561)	θ value	θ > 10 (rank : 1557)
Query Neighborhood Hits	1371	Target Neighborhood Hits	77	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IX95	Gene names	CTAGE3
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 3 (cTAGE-3 protein).

SURF6_HUMAN
NC score	0.087521 (rank : 1562)	θ value	θ > 10 (rank : 2220)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	71
SwissProt Accessions	O75683, Q9BRK9, Q9BTZ5, Q9UK24	Gene names	SURF6, SURF-6
Domain Architecture
Description	Surfeit locus protein 6.

FMNL_MOUSE
NC score	0.087427 (rank : 1563)	θ value	θ > 10 (rank : 1677)
Query Neighborhood Hits	1371	Target Neighborhood Hits	428	Shared Neighborhood Hits	184
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

AR13B_HUMAN
NC score	0.087409 (rank : 1564)	θ value	0.279714 (rank : 873)
Query Neighborhood Hits	1371	Target Neighborhood Hits	528	Shared Neighborhood Hits	238
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

A4_HUMAN
NC score	0.087272 (rank : 1565)	θ value	6.88961 (rank : 1279)
Query Neighborhood Hits	1371	Target Neighborhood Hits	274	Shared Neighborhood Hits	181
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

SASH1_HUMAN
NC score	0.087160 (rank : 1566)	θ value	0.365318 (rank : 922)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	87
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SCG3_MOUSE
NC score	0.086944 (rank : 1567)	θ value	θ > 10 (rank : 2117)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	110
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

UT14A_MOUSE
NC score	0.086861 (rank : 1568)	θ value	θ > 10 (rank : 2317)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	115
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

SRMS_HUMAN
NC score	0.086796 (rank : 1569)	θ value	θ > 10 (rank : 2186)
Query Neighborhood Hits	1371	Target Neighborhood Hits	946	Shared Neighborhood Hits	152
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

ATX3_HUMAN
NC score	0.086696 (rank : 1570)	θ value	θ > 10 (rank : 1435)
Query Neighborhood Hits	1371	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	P54252, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0	Gene names	ATXN3, ATX3, MJD, MJD1, SCA3
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein).

SHB_HUMAN
NC score	0.086638 (rank : 1571)	θ value	θ > 10 (rank : 2142)
Query Neighborhood Hits	1371	Target Neighborhood Hits	141	Shared Neighborhood Hits	68
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

TOLIP_MOUSE
NC score	0.086308 (rank : 1572)	θ value	0.00390308 (rank : 574)
Query Neighborhood Hits	1371	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

FMNL_HUMAN
NC score	0.086180 (rank : 1573)	θ value	θ > 10 (rank : 1676)
Query Neighborhood Hits	1371	Target Neighborhood Hits	529	Shared Neighborhood Hits	192
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PFD4_HUMAN
NC score	0.086008 (rank : 1574)	θ value	θ > 10 (rank : 2016)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NQP4, Q5TD11, Q92779	Gene names	PFDN4, PFD4
Domain Architecture	No domain graphic available
Description	Prefoldin subunit 4 (Protein C-1).

TRI29_MOUSE
NC score	0.085973 (rank : 1575)	θ value	θ > 10 (rank : 2294)
Query Neighborhood Hits	1371	Target Neighborhood Hits	306	Shared Neighborhood Hits	186
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

NRBF2_HUMAN
NC score	0.085969 (rank : 1576)	θ value	θ > 10 (rank : 1981)
Query Neighborhood Hits	1371	Target Neighborhood Hits	122	Shared Neighborhood Hits	92
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

BRD3_MOUSE
NC score	0.085967 (rank : 1577)	θ value	θ > 10 (rank : 1461)
Query Neighborhood Hits	1371	Target Neighborhood Hits	402	Shared Neighborhood Hits	197
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BST2_HUMAN
NC score	0.085860 (rank : 1578)	θ value	θ > 10 (rank : 1465)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	64
SwissProt Accessions	Q10589, Q53G07	Gene names	BST2
Domain Architecture
Description	Bone marrow stromal antigen 2 precursor (BST-2) (CD317 antigen) (HM1.24 antigen).

STABP_HUMAN
NC score	0.085853 (rank : 1579)	θ value	0.365318 (rank : 924)
Query Neighborhood Hits	1371	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	O95630, Q3MJE7	Gene names	STAMBP, AMSH
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

CA049_MOUSE
NC score	0.085771 (rank : 1580)	θ value	θ > 10 (rank : 1469)
Query Neighborhood Hits	1371	Target Neighborhood Hits	121	Shared Neighborhood Hits	93
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

MED4_HUMAN
NC score	0.085644 (rank : 1581)	θ value	1.06291 (rank : 1019)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NPJ6, Q5T912, Q6FHC4, Q6IA79, Q9BS95, Q9NYR5	Gene names	MED4, ARC36, DRIP36, VDRIP
Domain Architecture	No domain graphic available
Description	Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36) (Activator-recruited cofactor 36 kDa component) (ARC36) (TRAP/SMCC/PC2 subunit p36 subunit).

SHC3_MOUSE
NC score	0.085434 (rank : 1582)	θ value	θ > 10 (rank : 2149)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	66
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

CDC5L_MOUSE
NC score	0.085407 (rank : 1583)	θ value	θ > 10 (rank : 1498)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	117
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

KIF9_MOUSE
NC score	0.085201 (rank : 1584)	θ value	θ > 10 (rank : 1827)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WV04, O35070	Gene names	Kif9
Domain Architecture
Description	Kinesin-like protein KIF9.

BMX_HUMAN
NC score	0.085089 (rank : 1585)	θ value	θ > 10 (rank : 1455)
Query Neighborhood Hits	1371	Target Neighborhood Hits	942	Shared Neighborhood Hits	135
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

PERQ1_MOUSE
NC score	0.084736 (rank : 1586)	θ value	θ > 10 (rank : 2015)
Query Neighborhood Hits	1371	Target Neighborhood Hits	215	Shared Neighborhood Hits	120
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

KIF1B_HUMAN
NC score	0.084625 (rank : 1587)	θ value	θ > 10 (rank : 1814)
Query Neighborhood Hits	1371	Target Neighborhood Hits	178	Shared Neighborhood Hits	102
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

BMX_MOUSE
NC score	0.084544 (rank : 1588)	θ value	θ > 10 (rank : 1456)
Query Neighborhood Hits	1371	Target Neighborhood Hits	912	Shared Neighborhood Hits	130
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

A4_MOUSE
NC score	0.084538 (rank : 1589)	θ value	θ > 10 (rank : 1375)
Query Neighborhood Hits	1371	Target Neighborhood Hits	275	Shared Neighborhood Hits	180
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

PROX1_HUMAN
NC score	0.084307 (rank : 1590)	θ value	θ > 10 (rank : 2040)
Query Neighborhood Hits	1371	Target Neighborhood Hits	171	Shared Neighborhood Hits	121
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

BAG1_HUMAN
NC score	0.084252 (rank : 1591)	θ value	0.125558 (rank : 804)
Query Neighborhood Hits	1371	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q99933, O75315, Q14414, Q9Y2V4	Gene names	BAG1
Domain Architecture
Description	BAG family molecular chaperone regulator 1 (BCL-2-binding athanogene- 1) (BAG-1) (Glucocorticoid receptor-associated protein RAP46).

KIF12_HUMAN
NC score	0.084103 (rank : 1592)	θ value	θ > 10 (rank : 1811)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	91
SwissProt Accessions	Q96FN5, Q5TBE0	Gene names	KIF12
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF12.

TRAF5_MOUSE
NC score	0.084100 (rank : 1593)	θ value	θ > 10 (rank : 2289)
Query Neighborhood Hits	1371	Target Neighborhood Hits	355	Shared Neighborhood Hits	182
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

IQGA1_MOUSE
NC score	0.084097 (rank : 1594)	θ value	θ > 10 (rank : 1747)
Query Neighborhood Hits	1371	Target Neighborhood Hits	219	Shared Neighborhood Hits	134
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

APS_HUMAN
NC score	0.084034 (rank : 1595)	θ value	θ > 10 (rank : 1424)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

SHD_MOUSE
NC score	0.084009 (rank : 1596)	θ value	θ > 10 (rank : 2151)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	67
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

MATK_MOUSE
NC score	0.083971 (rank : 1597)	θ value	θ > 10 (rank : 1903)
Query Neighborhood Hits	1371	Target Neighborhood Hits	952	Shared Neighborhood Hits	153
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

TMCC3_HUMAN
NC score	0.083949 (rank : 1598)	θ value	θ > 10 (rank : 2277)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	160
SwissProt Accessions	Q9ULS5, Q8IWB2	Gene names	TMCC3, KIAA1145
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

FLOT1_MOUSE
NC score	0.083819 (rank : 1599)	θ value	θ > 10 (rank : 1673)
Query Neighborhood Hits	1371	Target Neighborhood Hits	128	Shared Neighborhood Hits	93
SwissProt Accessions	O08917	Gene names	Flot1
Domain Architecture
Description	Flotillin-1.

RBBP6_MOUSE
NC score	0.083786 (rank : 1600)	θ value	θ > 10 (rank : 2065)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1014	Shared Neighborhood Hits	230
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

APC_MOUSE
NC score	0.083778 (rank : 1601)	θ value	θ > 10 (rank : 1415)
Query Neighborhood Hits	1371	Target Neighborhood Hits	441	Shared Neighborhood Hits	170
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

GRB14_MOUSE
NC score	0.083700 (rank : 1602)	θ value	θ > 10 (rank : 1708)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

TLK2_HUMAN
NC score	0.083434 (rank : 1603)	θ value	0.0961366 (rank : 798)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1044	Shared Neighborhood Hits	270
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

SHC1_HUMAN
NC score	0.083412 (rank : 1604)	θ value	θ > 10 (rank : 2144)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	69
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

CREB3_HUMAN
NC score	0.083355 (rank : 1605)	θ value	0.365318 (rank : 901)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	83
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

DDX23_HUMAN
NC score	0.083280 (rank : 1606)	θ value	0.0961366 (rank : 779)
Query Neighborhood Hits	1371	Target Neighborhood Hits	486	Shared Neighborhood Hits	284
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

CSKP_HUMAN
NC score	0.083182 (rank : 1607)	θ value	0.00509761 (rank : 580)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1022	Shared Neighborhood Hits	198
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

MYOC_MOUSE
NC score	0.083068 (rank : 1608)	θ value	θ > 10 (rank : 1949)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	172
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

LAMA1_HUMAN
NC score	0.082998 (rank : 1609)	θ value	θ > 10 (rank : 1857)
Query Neighborhood Hits	1371	Target Neighborhood Hits	804	Shared Neighborhood Hits	237
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

RIF1_HUMAN
NC score	0.082939 (rank : 1610)	θ value	θ > 10 (rank : 2080)
Query Neighborhood Hits	1371	Target Neighborhood Hits	320	Shared Neighborhood Hits	146
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

DLG2_MOUSE
NC score	0.082846 (rank : 1611)	θ value	1.38821 (rank : 1050)
Query Neighborhood Hits	1371	Target Neighborhood Hits	271	Shared Neighborhood Hits	105
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

SHC1_MOUSE
NC score	0.082828 (rank : 1612)	θ value	θ > 10 (rank : 2145)
Query Neighborhood Hits	1371	Target Neighborhood Hits	180	Shared Neighborhood Hits	69
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHD_HUMAN
NC score	0.082691 (rank : 1613)	θ value	θ > 10 (rank : 2150)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	70
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

DLG2_HUMAN
NC score	0.082656 (rank : 1614)	θ value	1.06291 (rank : 1010)
Query Neighborhood Hits	1371	Target Neighborhood Hits	279	Shared Neighborhood Hits	105
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

HSH2D_HUMAN
NC score	0.082502 (rank : 1615)	θ value	θ > 10 (rank : 1729)
Query Neighborhood Hits	1371	Target Neighborhood Hits	159	Shared Neighborhood Hits	59
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

MATK_HUMAN
NC score	0.082436 (rank : 1616)	θ value	θ > 10 (rank : 1902)
Query Neighborhood Hits	1371	Target Neighborhood Hits	954	Shared Neighborhood Hits	149
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

KRHB2_MOUSE
NC score	0.081968 (rank : 1617)	θ value	θ > 10 (rank : 1845)
Query Neighborhood Hits	1371	Target Neighborhood Hits	233	Shared Neighborhood Hits	166
SwissProt Accessions	Q99M74	Gene names	Krthb2, Krt2-20
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

GRB14_HUMAN
NC score	0.081755 (rank : 1618)	θ value	θ > 10 (rank : 1707)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	58
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

ACTN3_HUMAN
NC score	0.081684 (rank : 1619)	θ value	θ > 10 (rank : 1388)
Query Neighborhood Hits	1371	Target Neighborhood Hits	272	Shared Neighborhood Hits	158
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

CSKP_MOUSE
NC score	0.081651 (rank : 1620)	θ value	0.0431538 (rank : 708)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1027	Shared Neighborhood Hits	205
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

BAP31_MOUSE
NC score	0.081601 (rank : 1621)	θ value	θ > 10 (rank : 1437)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	101
SwissProt Accessions	Q61335, Q9D0E9, Q9D8G7	Gene names	Bcap31, Bap31
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31).

SHC2_HUMAN
NC score	0.081471 (rank : 1622)	θ value	θ > 10 (rank : 2146)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	66
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

CCD16_HUMAN
NC score	0.081301 (rank : 1623)	θ value	θ > 10 (rank : 1475)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	116
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

BAZ2A_HUMAN
NC score	0.081169 (rank : 1624)	θ value	θ > 10 (rank : 1438)
Query Neighborhood Hits	1371	Target Neighborhood Hits	780	Shared Neighborhood Hits	245
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

KIF1B_MOUSE
NC score	0.081110 (rank : 1625)	θ value	θ > 10 (rank : 1815)
Query Neighborhood Hits	1371	Target Neighborhood Hits	167	Shared Neighborhood Hits	86
SwissProt Accessions	Q60575, Q9R0B4, Q9WVE5, Q9Z119	Gene names	Kif1b
Domain Architecture
Description	Kinesin-like protein KIF1B.

EVC_HUMAN
NC score	0.081030 (rank : 1626)	θ value	θ > 10 (rank : 1647)
Query Neighborhood Hits	1371	Target Neighborhood Hits	129	Shared Neighborhood Hits	92
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

SASH1_MOUSE
NC score	0.080605 (rank : 1627)	θ value	1.06291 (rank : 1029)
Query Neighborhood Hits	1371	Target Neighborhood Hits	263	Shared Neighborhood Hits	87
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

KIF22_HUMAN
NC score	0.080508 (rank : 1628)	θ value	θ > 10 (rank : 1818)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	70
SwissProt Accessions	Q14807, O94814, Q9BT46	Gene names	KIF22, KID, KNSL4
Domain Architecture
Description	Kinesin-like protein KIF22 (Kinesin-like DNA-binding protein) (Kinesin-like protein 4).

NPBL_MOUSE
NC score	0.080460 (rank : 1629)	θ value	0.0736092 (rank : 762)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1041	Shared Neighborhood Hits	230
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TBCD1_HUMAN
NC score	0.080365 (rank : 1630)	θ value	θ > 10 (rank : 2253)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	168
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

FCER2_MOUSE
NC score	0.080275 (rank : 1631)	θ value	θ > 10 (rank : 1667)
Query Neighborhood Hits	1371	Target Neighborhood Hits	392	Shared Neighborhood Hits	215
SwissProt Accessions	P20693, Q61556, Q61557	Gene names	Fcer2, Fcer2a
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IGE receptor) (Fc-epsilon-RII) (CD23 antigen).

SHC3_HUMAN
NC score	0.080208 (rank : 1632)	θ value	θ > 10 (rank : 2148)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	62
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

NUP54_MOUSE
NC score	0.080191 (rank : 1633)	θ value	θ > 10 (rank : 1991)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BTS4, Q3TSI2, Q8BU42	Gene names	Nup54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

CLCB_MOUSE
NC score	0.080131 (rank : 1634)	θ value	0.365318 (rank : 897)
Query Neighborhood Hits	1371	Target Neighborhood Hits	119	Shared Neighborhood Hits	83
SwissProt Accessions	Q6IRU5, Q8BR04, Q8CDX9, Q9CV35	Gene names	Cltb
Domain Architecture	No domain graphic available
Description	Clathrin light chain B (Lcb).

SEPT8_MOUSE
NC score	0.080073 (rank : 1635)	θ value	θ > 10 (rank : 2127)
Query Neighborhood Hits	1371	Target Neighborhood Hits	251	Shared Neighborhood Hits	183
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

FA76B_HUMAN
NC score	0.079990 (rank : 1636)	θ value	θ > 10 (rank : 1657)
Query Neighborhood Hits	1371	Target Neighborhood Hits	184	Shared Neighborhood Hits	130
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

APXL_HUMAN
NC score	0.079932 (rank : 1637)	θ value	θ > 10 (rank : 1426)
Query Neighborhood Hits	1371	Target Neighborhood Hits	553	Shared Neighborhood Hits	161
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

DFFA_HUMAN
NC score	0.079909 (rank : 1638)	θ value	θ > 10 (rank : 1581)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	80
SwissProt Accessions	O00273, Q96I97, Q9Y6C6	Gene names	DFFA, DFF1, DFF45
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

MYT1_HUMAN
NC score	0.079891 (rank : 1639)	θ value	θ > 10 (rank : 1958)
Query Neighborhood Hits	1371	Target Neighborhood Hits	475	Shared Neighborhood Hits	225
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

PROX1_MOUSE
NC score	0.079613 (rank : 1640)	θ value	θ > 10 (rank : 2041)
Query Neighborhood Hits	1371	Target Neighborhood Hits	184	Shared Neighborhood Hits	123
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

SH21A_MOUSE
NC score	0.079554 (rank : 1641)	θ value	θ > 10 (rank : 2135)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

DLG3_HUMAN
NC score	0.079545 (rank : 1642)	θ value	1.81305 (rank : 1086)
Query Neighborhood Hits	1371	Target Neighborhood Hits	269	Shared Neighborhood Hits	105
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

CDC5L_HUMAN
NC score	0.079498 (rank : 1643)	θ value	θ > 10 (rank : 1497)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	121
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

DLG3_MOUSE
NC score	0.079397 (rank : 1644)	θ value	1.81305 (rank : 1087)
Query Neighborhood Hits	1371	Target Neighborhood Hits	274	Shared Neighborhood Hits	105
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

TMCC3_MOUSE
NC score	0.079357 (rank : 1645)	θ value	θ > 10 (rank : 2278)
Query Neighborhood Hits	1371	Target Neighborhood Hits	192	Shared Neighborhood Hits	143
SwissProt Accessions	Q8R310	Gene names	Tmcc3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

MDN1_HUMAN
NC score	0.079242 (rank : 1646)	θ value	θ > 10 (rank : 1904)
Query Neighborhood Hits	1371	Target Neighborhood Hits	662	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

OXR1_HUMAN
NC score	0.079207 (rank : 1647)	θ value	θ > 10 (rank : 1999)
Query Neighborhood Hits	1371	Target Neighborhood Hits	282	Shared Neighborhood Hits	130
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

KRHB2_HUMAN
NC score	0.079131 (rank : 1648)	θ value	θ > 10 (rank : 1844)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NSB4	Gene names	KRTHB2
Domain Architecture
Description	Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2).

RASA3_MOUSE
NC score	0.078988 (rank : 1649)	θ value	θ > 10 (rank : 2062)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	78
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

OBSCN_HUMAN
NC score	0.078877 (rank : 1650)	θ value	1.38821 (rank : 1060)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1931	Shared Neighborhood Hits	203
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TMCC2_MOUSE
NC score	0.078810 (rank : 1651)	θ value	θ > 10 (rank : 2276)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	158
SwissProt Accessions	Q80W04, Q6A061	Gene names	Tmcc2, Kiaa0481
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 2.

ANGP1_HUMAN
NC score	0.078661 (rank : 1652)	θ value	θ > 10 (rank : 1402)
Query Neighborhood Hits	1371	Target Neighborhood Hits	254	Shared Neighborhood Hits	184
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

RRMJ3_MOUSE
NC score	0.078630 (rank : 1653)	θ value	5.27518 (rank : 1264)
Query Neighborhood Hits	1371	Target Neighborhood Hits	163	Shared Neighborhood Hits	103
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

ST18_HUMAN
NC score	0.078573 (rank : 1654)	θ value	θ > 10 (rank : 2193)
Query Neighborhood Hits	1371	Target Neighborhood Hits	252	Shared Neighborhood Hits	166
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

ANR38_MOUSE
NC score	0.078430 (rank : 1655)	θ value	θ > 10 (rank : 1413)
Query Neighborhood Hits	1371	Target Neighborhood Hits	512	Shared Neighborhood Hits	200
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

SHC2_MOUSE
NC score	0.077936 (rank : 1656)	θ value	θ > 10 (rank : 2147)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

NOC3L_HUMAN
NC score	0.077740 (rank : 1657)	θ value	θ > 10 (rank : 1973)
Query Neighborhood Hits	1371	Target Neighborhood Hits	135	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

FA76B_MOUSE
NC score	0.077665 (rank : 1658)	θ value	θ > 10 (rank : 1658)
Query Neighborhood Hits	1371	Target Neighborhood Hits	181	Shared Neighborhood Hits	129
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

CTR9_MOUSE
NC score	0.077615 (rank : 1659)	θ value	θ > 10 (rank : 1560)
Query Neighborhood Hits	1371	Target Neighborhood Hits	427	Shared Neighborhood Hits	174
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

SH21A_HUMAN
NC score	0.077542 (rank : 1660)	θ value	θ > 10 (rank : 2134)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

ZFY28_HUMAN
NC score	0.077509 (rank : 1661)	θ value	θ > 10 (rank : 2351)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

PLCD1_HUMAN
NC score	0.077426 (rank : 1662)	θ value	θ > 10 (rank : 2035)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	63
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

SEPT6_MOUSE
NC score	0.077285 (rank : 1663)	θ value	0.62314 (rank : 972)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	185
SwissProt Accessions	Q9R1T4, Q91XH2, Q9CZ94	Gene names	Sept6
Domain Architecture
Description	Septin-6.

KIF9_HUMAN
NC score	0.077243 (rank : 1664)	θ value	θ > 10 (rank : 1826)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAQ2, Q86Z28, Q9H8A4	Gene names	KIF9
Domain Architecture
Description	Kinesin-like protein KIF9.

NBN_HUMAN
NC score	0.077192 (rank : 1665)	θ value	8.99809 (rank : 1345)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	110
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

TMCC2_HUMAN
NC score	0.077095 (rank : 1666)	θ value	θ > 10 (rank : 2275)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	153
SwissProt Accessions	O75069, Q6ZN09	Gene names	TMCC2, KIAA0481
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 2 (Cerebral protein 11).

LNK_HUMAN
NC score	0.077054 (rank : 1667)	θ value	θ > 10 (rank : 1881)
Query Neighborhood Hits	1371	Target Neighborhood Hits	151	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

BRD3_HUMAN
NC score	0.076937 (rank : 1668)	θ value	θ > 10 (rank : 1460)
Query Neighborhood Hits	1371	Target Neighborhood Hits	369	Shared Neighborhood Hits	170
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

PLCD1_MOUSE
NC score	0.076893 (rank : 1669)	θ value	θ > 10 (rank : 2036)
Query Neighborhood Hits	1371	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

THOC2_HUMAN
NC score	0.076553 (rank : 1670)	θ value	θ > 10 (rank : 2268)
Query Neighborhood Hits	1371	Target Neighborhood Hits	337	Shared Neighborhood Hits	135
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

RHG12_MOUSE
NC score	0.076436 (rank : 1671)	θ value	θ > 10 (rank : 2078)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	90
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CTR9_HUMAN
NC score	0.076373 (rank : 1672)	θ value	θ > 10 (rank : 1559)
Query Neighborhood Hits	1371	Target Neighborhood Hits	383	Shared Neighborhood Hits	160
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

FA44A_HUMAN
NC score	0.076341 (rank : 1673)	θ value	θ > 10 (rank : 1650)
Query Neighborhood Hits	1371	Target Neighborhood Hits	280	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

NARGL_MOUSE
NC score	0.076227 (rank : 1674)	θ value	0.47712 (rank : 946)
Query Neighborhood Hits	1371	Target Neighborhood Hits	175	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

FES_MOUSE
NC score	0.076186 (rank : 1675)	θ value	3.0926 (rank : 1173)
Query Neighborhood Hits	1371	Target Neighborhood Hits	980	Shared Neighborhood Hits	203
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

K1914_MOUSE
NC score	0.076170 (rank : 1676)	θ value	θ > 10 (rank : 1771)
Query Neighborhood Hits	1371	Target Neighborhood Hits	216	Shared Neighborhood Hits	105
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

ACTN1_HUMAN
NC score	0.076160 (rank : 1677)	θ value	θ > 10 (rank : 1384)
Query Neighborhood Hits	1371	Target Neighborhood Hits	221	Shared Neighborhood Hits	133
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

TOLIP_HUMAN
NC score	0.076151 (rank : 1678)	θ value	0.0193708 (rank : 671)
Query Neighborhood Hits	1371	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

DLG1_HUMAN
NC score	0.075847 (rank : 1679)	θ value	1.81305 (rank : 1085)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	108
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

TPX2_HUMAN
NC score	0.075787 (rank : 1680)	θ value	θ > 10 (rank : 2288)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

TRI29_HUMAN
NC score	0.075783 (rank : 1681)	θ value	θ > 10 (rank : 2293)
Query Neighborhood Hits	1371	Target Neighborhood Hits	273	Shared Neighborhood Hits	163
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

CLCB_HUMAN
NC score	0.075778 (rank : 1682)	θ value	0.365318 (rank : 896)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	85
SwissProt Accessions	P09497, Q6FHW1	Gene names	CLTB
Domain Architecture
Description	Clathrin light chain B (Lcb).

TBCD1_MOUSE
NC score	0.075506 (rank : 1683)	θ value	θ > 10 (rank : 2254)
Query Neighborhood Hits	1371	Target Neighborhood Hits	241	Shared Neighborhood Hits	154
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

UBF1_MOUSE
NC score	0.075457 (rank : 1684)	θ value	6.88961 (rank : 1322)
Query Neighborhood Hits	1371	Target Neighborhood Hits	419	Shared Neighborhood Hits	156
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

RHG09_HUMAN
NC score	0.075395 (rank : 1685)	θ value	1.81305 (rank : 1108)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CENPU_MOUSE
NC score	0.075335 (rank : 1686)	θ value	θ > 10 (rank : 1506)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	91
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

ANGP1_MOUSE
NC score	0.075237 (rank : 1687)	θ value	θ > 10 (rank : 1403)
Query Neighborhood Hits	1371	Target Neighborhood Hits	252	Shared Neighborhood Hits	176
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

DIAP2_HUMAN
NC score	0.075174 (rank : 1688)	θ value	θ > 10 (rank : 1585)
Query Neighborhood Hits	1371	Target Neighborhood Hits	342	Shared Neighborhood Hits	177
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

PALM_HUMAN
NC score	0.075128 (rank : 1689)	θ value	θ > 10 (rank : 2006)
Query Neighborhood Hits	1371	Target Neighborhood Hits	136	Shared Neighborhood Hits	95
SwissProt Accessions	O75781, O43359, O95673, Q92559, Q9UPJ4, Q9UQS2, Q9UQS3	Gene names	PALM, KIAA0270
Domain Architecture
Description	Paralemmin.

P3C2B_HUMAN
NC score	0.074939 (rank : 1690)	θ value	θ > 10 (rank : 2005)
Query Neighborhood Hits	1371	Target Neighborhood Hits	148	Shared Neighborhood Hits	75
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

FES_HUMAN
NC score	0.074910 (rank : 1691)	θ value	θ > 10 (rank : 1668)
Query Neighborhood Hits	1371	Target Neighborhood Hits	978	Shared Neighborhood Hits	194
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

TBCD4_MOUSE
NC score	0.074850 (rank : 1692)	θ value	θ > 10 (rank : 2257)
Query Neighborhood Hits	1371	Target Neighborhood Hits	276	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

LNK_MOUSE
NC score	0.074792 (rank : 1693)	θ value	θ > 10 (rank : 1882)
Query Neighborhood Hits	1371	Target Neighborhood Hits	132	Shared Neighborhood Hits	56
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

KIF2C_HUMAN
NC score	0.074737 (rank : 1694)	θ value	6.88961 (rank : 1301)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	81
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

IF31_MOUSE
NC score	0.074722 (rank : 1695)	θ value	θ > 10 (rank : 1735)
Query Neighborhood Hits	1371	Target Neighborhood Hits	105	Shared Neighborhood Hits	73
SwissProt Accessions	Q66JS6, Q8BUW6	Gene names	Eif3s1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha).

RGAP1_HUMAN
NC score	0.074671 (rank : 1696)	θ value	θ > 10 (rank : 2074)
Query Neighborhood Hits	1371	Target Neighborhood Hits	189	Shared Neighborhood Hits	101
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

K0841_HUMAN
NC score	0.074516 (rank : 1697)	θ value	θ > 10 (rank : 1768)
Query Neighborhood Hits	1371	Target Neighborhood Hits	119	Shared Neighborhood Hits	91
SwissProt Accessions	O94927, Q6P2P7, Q7L3D5, Q96CT8	Gene names	KIAA0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

CJ049_HUMAN
NC score	0.074479 (rank : 1698)	θ value	θ > 10 (rank : 1523)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

ZAP70_MOUSE
NC score	0.074434 (rank : 1699)	θ value	θ > 10 (rank : 2343)
Query Neighborhood Hits	1371	Target Neighborhood Hits	905	Shared Neighborhood Hits	128
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

HDAC5_MOUSE
NC score	0.074401 (rank : 1700)	θ value	θ > 10 (rank : 1716)
Query Neighborhood Hits	1371	Target Neighborhood Hits	310	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

GRB7_MOUSE
NC score	0.074290 (rank : 1701)	θ value	θ > 10 (rank : 1710)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	65
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

ANGP4_MOUSE
NC score	0.074157 (rank : 1702)	θ value	4.03905 (rank : 1196)
Query Neighborhood Hits	1371	Target Neighborhood Hits	220	Shared Neighborhood Hits	146
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ZAP70_HUMAN
NC score	0.073944 (rank : 1703)	θ value	θ > 10 (rank : 2342)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	126
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

RHG12_HUMAN
NC score	0.073905 (rank : 1704)	θ value	θ > 10 (rank : 2077)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CCD82_HUMAN
NC score	0.073904 (rank : 1705)	θ value	θ > 10 (rank : 1485)
Query Neighborhood Hits	1371	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

KIF25_HUMAN
NC score	0.073850 (rank : 1706)	θ value	θ > 10 (rank : 1819)
Query Neighborhood Hits	1371	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIL4, O94775	Gene names	KIF25, KNSL3
Domain Architecture
Description	Kinesin-like protein KIF25 (Kinesin-like protein 3).

TAK1L_MOUSE
NC score	0.073634 (rank : 1707)	θ value	θ > 10 (rank : 2251)
Query Neighborhood Hits	1371	Target Neighborhood Hits	106	Shared Neighborhood Hits	88
SwissProt Accessions	P58500	Gene names	Tak1l, ORF63
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

CHMP5_HUMAN
NC score	0.073589 (rank : 1708)	θ value	θ > 10 (rank : 1519)
Query Neighborhood Hits	1371	Target Neighborhood Hits	103	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZZ3, Q5VXW2, Q96AV2, Q9HB68, Q9NYS4, Q9Y323	Gene names	CHMP5, C9orf83, SNF7DC2
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (Vacuolar protein sorting 60) (Vps60) (hVps60) (SNF7 domain-containing protein 2).

APLP2_MOUSE
NC score	0.073581 (rank : 1709)	θ value	3.0926 (rank : 1165)
Query Neighborhood Hits	1371	Target Neighborhood Hits	186	Shared Neighborhood Hits	111
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

KIF12_MOUSE
NC score	0.073540 (rank : 1710)	θ value	θ > 10 (rank : 1812)
Query Neighborhood Hits	1371	Target Neighborhood Hits	94	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D2Z8, O35061	Gene names	Kif12
Domain Architecture
Description	Kinesin-like protein KIF12.

LRC48_HUMAN
NC score	0.073523 (rank : 1711)	θ value	θ > 10 (rank : 1883)
Query Neighborhood Hits	1371	Target Neighborhood Hits	324	Shared Neighborhood Hits	124
SwissProt Accessions	Q9H069, Q86SF9, Q86W73, Q8IWG0	Gene names	LRRC48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

EBP2_MOUSE
NC score	0.073404 (rank : 1712)	θ value	0.163984 (rank : 827)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D903, Q3TKB5	Gene names	Ebna1bp2, Ebp2
Domain Architecture
Description	Probable rRNA-processing protein EBP2.

UT14B_MOUSE
NC score	0.073227 (rank : 1713)	θ value	θ > 10 (rank : 2318)
Query Neighborhood Hits	1371	Target Neighborhood Hits	226	Shared Neighborhood Hits	135
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

MYST3_HUMAN
NC score	0.073021 (rank : 1714)	θ value	θ > 10 (rank : 1954)
Query Neighborhood Hits	1371	Target Neighborhood Hits	772	Shared Neighborhood Hits	232
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

TNNI2_HUMAN
NC score	0.073020 (rank : 1715)	θ value	0.163984 (rank : 835)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	P48788	Gene names	TNNI2
Domain Architecture
Description	Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).

LAMB3_HUMAN
NC score	0.072972 (rank : 1716)	θ value	θ > 10 (rank : 1866)
Query Neighborhood Hits	1371	Target Neighborhood Hits	461	Shared Neighborhood Hits	186
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

ZFYV9_HUMAN
NC score	0.072931 (rank : 1717)	θ value	θ > 10 (rank : 2354)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

USBP1_HUMAN
NC score	0.072921 (rank : 1718)	θ value	θ > 10 (rank : 2313)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

SNIP_MOUSE
NC score	0.072906 (rank : 1719)	θ value	θ > 10 (rank : 2162)
Query Neighborhood Hits	1371	Target Neighborhood Hits	319	Shared Neighborhood Hits	138
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

PHF14_HUMAN
NC score	0.072873 (rank : 1720)	θ value	θ > 10 (rank : 2019)
Query Neighborhood Hits	1371	Target Neighborhood Hits	447	Shared Neighborhood Hits	196
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

ACTN1_MOUSE
NC score	0.072699 (rank : 1721)	θ value	θ > 10 (rank : 1385)
Query Neighborhood Hits	1371	Target Neighborhood Hits	216	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

DLG1_MOUSE
NC score	0.072597 (rank : 1722)	θ value	2.36792 (rank : 1133)
Query Neighborhood Hits	1371	Target Neighborhood Hits	285	Shared Neighborhood Hits	102
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

SDCG1_HUMAN
NC score	0.072537 (rank : 1723)	θ value	θ > 10 (rank : 2118)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	103
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

PSIP1_HUMAN
NC score	0.072508 (rank : 1724)	θ value	θ > 10 (rank : 2044)
Query Neighborhood Hits	1371	Target Neighborhood Hits	341	Shared Neighborhood Hits	153
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

KIF1C_MOUSE
NC score	0.072319 (rank : 1725)	θ value	θ > 10 (rank : 1817)
Query Neighborhood Hits	1371	Target Neighborhood Hits	171	Shared Neighborhood Hits	69
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

TAD3L_HUMAN
NC score	0.072292 (rank : 1726)	θ value	θ > 10 (rank : 2244)
Query Neighborhood Hits	1371	Target Neighborhood Hits	189	Shared Neighborhood Hits	115
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

RGAP1_MOUSE
NC score	0.072235 (rank : 1727)	θ value	2.36792 (rank : 1154)
Query Neighborhood Hits	1371	Target Neighborhood Hits	185	Shared Neighborhood Hits	88
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

ST18_MOUSE
NC score	0.072122 (rank : 1728)	θ value	θ > 10 (rank : 2194)
Query Neighborhood Hits	1371	Target Neighborhood Hits	248	Shared Neighborhood Hits	159
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

LUC7L_HUMAN
NC score	0.072109 (rank : 1729)	θ value	θ > 10 (rank : 1889)
Query Neighborhood Hits	1371	Target Neighborhood Hits	130	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQ29, Q96S32, Q9NPH4	Gene names	LUC7L, LUC7L1
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 1 (SR+89) (Putative SR protein LUC7B1).

TIM44_HUMAN
NC score	0.072048 (rank : 1730)	θ value	θ > 10 (rank : 2269)
Query Neighborhood Hits	1371	Target Neighborhood Hits	141	Shared Neighborhood Hits	111
SwissProt Accessions	O43615, Q8N193	Gene names	TIMM44, MIMT44, TIM44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

KIF1C_HUMAN
NC score	0.072006 (rank : 1731)	θ value	θ > 10 (rank : 1816)
Query Neighborhood Hits	1371	Target Neighborhood Hits	128	Shared Neighborhood Hits	58
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

CF153_MOUSE
NC score	0.071890 (rank : 1732)	θ value	θ > 10 (rank : 1512)
Query Neighborhood Hits	1371	Target Neighborhood Hits	78	Shared Neighborhood Hits	51
SwissProt Accessions	Q3UFY0, Q91X71	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153 homolog.

NEK11_HUMAN
NC score	0.071865 (rank : 1733)	θ value	4.03905 (rank : 1216)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1043	Shared Neighborhood Hits	231
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

KSYK_MOUSE
NC score	0.071740 (rank : 1734)	θ value	θ > 10 (rank : 1855)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	130
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

USH1C_HUMAN
NC score	0.071672 (rank : 1735)	θ value	θ > 10 (rank : 2315)
Query Neighborhood Hits	1371	Target Neighborhood Hits	327	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

SNP25_HUMAN
NC score	0.071668 (rank : 1736)	θ value	θ > 10 (rank : 2163)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	P60880, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	SNAP25, SNAP
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

SNP25_MOUSE
NC score	0.071668 (rank : 1737)	θ value	θ > 10 (rank : 2164)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	P60879, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	Snap25, Snap
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

IWS1_HUMAN
NC score	0.071354 (rank : 1738)	θ value	θ > 10 (rank : 1754)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1241	Shared Neighborhood Hits	244
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KSYK_HUMAN
NC score	0.071078 (rank : 1739)	θ value	θ > 10 (rank : 1854)
Query Neighborhood Hits	1371	Target Neighborhood Hits	901	Shared Neighborhood Hits	127
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

S6OS1_MOUSE
NC score	0.071058 (rank : 1740)	θ value	θ > 10 (rank : 2110)
Query Neighborhood Hits	1371	Target Neighborhood Hits	105	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CTN5, Q9D5F5, Q9D5Y9	Gene names	Six6os1
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

EBP2_HUMAN
NC score	0.070956 (rank : 1741)	θ value	0.0736092 (rank : 753)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	Q99848, Q96A66	Gene names	EBNA1BP2, EBP2
Domain Architecture
Description	Probable rRNA-processing protein EBP2 (EBNA1-binding protein 2) (Nucleolar protein p40).

TAD3L_MOUSE
NC score	0.070955 (rank : 1742)	θ value	θ > 10 (rank : 2245)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	114
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

BAZ1B_MOUSE
NC score	0.070771 (rank : 1743)	θ value	5.27518 (rank : 1234)
Query Neighborhood Hits	1371	Target Neighborhood Hits	394	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

DLG4_HUMAN
NC score	0.070734 (rank : 1744)	θ value	θ > 10 (rank : 1589)
Query Neighborhood Hits	1371	Target Neighborhood Hits	286	Shared Neighborhood Hits	110
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PTMS_HUMAN
NC score	0.070723 (rank : 1745)	θ value	θ > 10 (rank : 2046)
Query Neighborhood Hits	1371	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PSIP1_MOUSE
NC score	0.070697 (rank : 1746)	θ value	θ > 10 (rank : 2045)
Query Neighborhood Hits	1371	Target Neighborhood Hits	313	Shared Neighborhood Hits	128
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

MTSS1_HUMAN
NC score	0.070680 (rank : 1747)	θ value	θ > 10 (rank : 1930)
Query Neighborhood Hits	1371	Target Neighborhood Hits	504	Shared Neighborhood Hits	140
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

PALM_MOUSE
NC score	0.070444 (rank : 1748)	θ value	θ > 10 (rank : 2007)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

GRP3_HUMAN
NC score	0.070259 (rank : 1749)	θ value	θ > 10 (rank : 1711)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

RIMS4_MOUSE
NC score	0.070172 (rank : 1750)	θ value	θ > 10 (rank : 2086)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

VINC_HUMAN
NC score	0.070098 (rank : 1751)	θ value	θ > 10 (rank : 2324)
Query Neighborhood Hits	1371	Target Neighborhood Hits	145	Shared Neighborhood Hits	85
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

LRMP_HUMAN
NC score	0.070005 (rank : 1752)	θ value	θ > 10 (rank : 1884)
Query Neighborhood Hits	1371	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

GCF_HUMAN
NC score	0.069993 (rank : 1753)	θ value	θ > 10 (rank : 1693)
Query Neighborhood Hits	1371	Target Neighborhood Hits	107	Shared Neighborhood Hits	76
SwissProt Accessions	P16383, O95032	Gene names	TCF9, C2orf3
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9).

DYH9_HUMAN
NC score	0.069971 (rank : 1754)	θ value	θ > 10 (rank : 1604)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

DDIT3_HUMAN
NC score	0.069859 (rank : 1755)	θ value	θ > 10 (rank : 1572)
Query Neighborhood Hits	1371	Target Neighborhood Hits	167	Shared Neighborhood Hits	102
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

DEK_MOUSE
NC score	0.069810 (rank : 1756)	θ value	θ > 10 (rank : 1578)
Query Neighborhood Hits	1371	Target Neighborhood Hits	280	Shared Neighborhood Hits	102
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

JIP2_HUMAN
NC score	0.069798 (rank : 1757)	θ value	θ > 10 (rank : 1762)
Query Neighborhood Hits	1371	Target Neighborhood Hits	288	Shared Neighborhood Hits	80
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

RIMS4_HUMAN
NC score	0.069765 (rank : 1758)	θ value	θ > 10 (rank : 2085)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

KIF2A_HUMAN
NC score	0.069483 (rank : 1759)	θ value	θ > 10 (rank : 1820)
Query Neighborhood Hits	1371	Target Neighborhood Hits	94	Shared Neighborhood Hits	47
SwissProt Accessions	O00139, Q8N5Q7	Gene names	KIF2A, KIF2, KNS2
Domain Architecture
Description	Kinesin-like protein KIF2A (Kinesin-2) (HK2).

TNNI2_MOUSE
NC score	0.069471 (rank : 1760)	θ value	0.365318 (rank : 928)
Query Neighborhood Hits	1371	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	P13412	Gene names	Tnni2
Domain Architecture
Description	Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).

KIF2C_MOUSE
NC score	0.069422 (rank : 1761)	θ value	θ > 10 (rank : 1824)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	53
SwissProt Accessions	Q922S8	Gene names	Kif2c
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK).

ACK1_MOUSE
NC score	0.069235 (rank : 1762)	θ value	θ > 10 (rank : 1383)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1080	Shared Neighborhood Hits	160
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ACK1_HUMAN
NC score	0.068957 (rank : 1763)	θ value	θ > 10 (rank : 1382)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1140	Shared Neighborhood Hits	166
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

LCP2_MOUSE
NC score	0.068918 (rank : 1764)	θ value	θ > 10 (rank : 1875)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	62
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

KIF2A_MOUSE
NC score	0.068895 (rank : 1765)	θ value	θ > 10 (rank : 1821)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P28740	Gene names	Kif2a, Kif2, Kns2
Domain Architecture
Description	Kinesin-like protein KIF2A.

ING3_MOUSE
NC score	0.068883 (rank : 1766)	θ value	3.0926 (rank : 1176)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

SEPT6_HUMAN
NC score	0.068656 (rank : 1767)	θ value	0.813845 (rank : 995)
Query Neighborhood Hits	1371	Target Neighborhood Hits	220	Shared Neighborhood Hits	160
SwissProt Accessions	Q14141, Q5JTK0, Q969W5, Q96A13, Q96GR1, Q96P86, Q96P87	Gene names	SEPT6, KIAA0128, SEP2
Domain Architecture
Description	Septin-6.

ZFY16_MOUSE
NC score	0.068650 (rank : 1768)	θ value	θ > 10 (rank : 2346)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	28
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

CHCH6_MOUSE
NC score	0.068645 (rank : 1769)	θ value	θ > 10 (rank : 1514)
Query Neighborhood Hits	1371	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q91VN4	Gene names	Chchd6
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 6.

DYH11_HUMAN
NC score	0.068547 (rank : 1770)	θ value	θ > 10 (rank : 1601)
Query Neighborhood Hits	1371	Target Neighborhood Hits	234	Shared Neighborhood Hits	151
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

E41L2_MOUSE
NC score	0.068504 (rank : 1771)	θ value	3.0926 (rank : 1172)
Query Neighborhood Hits	1371	Target Neighborhood Hits	459	Shared Neighborhood Hits	188
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

CE110_MOUSE
NC score	0.068449 (rank : 1772)	θ value	θ > 10 (rank : 1502)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	108
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

CALM4_MOUSE
NC score	0.068429 (rank : 1773)	θ value	0.00298849 (rank : 545)
Query Neighborhood Hits	1371	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

DLG4_MOUSE
NC score	0.068274 (rank : 1774)	θ value	θ > 10 (rank : 1590)
Query Neighborhood Hits	1371	Target Neighborhood Hits	282	Shared Neighborhood Hits	106
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PLSI_HUMAN
NC score	0.068180 (rank : 1775)	θ value	0.0330416 (rank : 700)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	58
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

NUP54_HUMAN
NC score	0.068121 (rank : 1776)	θ value	θ > 10 (rank : 1990)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z3B4, Q96EA7, Q9NVL5, Q9P0I1	Gene names	NUP54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

ZFY21_MOUSE
NC score	0.068059 (rank : 1777)	θ value	θ > 10 (rank : 2350)
Query Neighborhood Hits	1371	Target Neighborhood Hits	72	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

CIP1_HUMAN
NC score	0.068023 (rank : 1778)	θ value	θ > 10 (rank : 1521)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPC3	Gene names	CCNB1IP1, C14orf18, HEI10
Domain Architecture	No domain graphic available
Description	Cyclin-B1-interacting protein 1 (EC 6.3.2.-) (Human enhancer of invasion 10) (E3 ubiquitin-protein ligase HEI10).

MNT_MOUSE
NC score	0.067941 (rank : 1779)	θ value	1.81305 (rank : 1101)
Query Neighborhood Hits	1371	Target Neighborhood Hits	432	Shared Neighborhood Hits	108
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SFR11_HUMAN
NC score	0.067901 (rank : 1780)	θ value	θ > 10 (rank : 2129)
Query Neighborhood Hits	1371	Target Neighborhood Hits	246	Shared Neighborhood Hits	95
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

NSBP1_MOUSE
NC score	0.067844 (rank : 1781)	θ value	θ > 10 (rank : 1986)
Query Neighborhood Hits	1371	Target Neighborhood Hits	681	Shared Neighborhood Hits	160
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

CHIO_MOUSE
NC score	0.067774 (rank : 1782)	θ value	θ > 10 (rank : 1518)
Query Neighborhood Hits	1371	Target Neighborhood Hits	130	Shared Neighborhood Hits	42
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CJ078_MOUSE
NC score	0.067705 (rank : 1783)	θ value	0.125558 (rank : 807)
Query Neighborhood Hits	1371	Target Neighborhood Hits	559	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

COG6_HUMAN
NC score	0.067689 (rank : 1784)	θ value	θ > 10 (rank : 1542)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y2V7, Q5T0U1, Q9ULT5	Gene names	COG6, KIAA1134
Domain Architecture
Description	Conserved oligomeric Golgi complex component 6.

UBF1_HUMAN
NC score	0.067589 (rank : 1785)	θ value	8.99809 (rank : 1367)
Query Neighborhood Hits	1371	Target Neighborhood Hits	415	Shared Neighborhood Hits	143
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

NEK1_MOUSE
NC score	0.067585 (rank : 1786)	θ value	θ > 10 (rank : 1968)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1311	Shared Neighborhood Hits	310
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

ZFY21_HUMAN
NC score	0.067507 (rank : 1787)	θ value	θ > 10 (rank : 2349)
Query Neighborhood Hits	1371	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY16_HUMAN
NC score	0.067498 (rank : 1788)	θ value	θ > 10 (rank : 2345)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

IKKB_MOUSE
NC score	0.067492 (rank : 1789)	θ value	2.36792 (rank : 1140)
Query Neighborhood Hits	1371	Target Neighborhood Hits	984	Shared Neighborhood Hits	220
SwissProt Accessions	O88351, Q9R1J6	Gene names	Ikbkb, Ikkb
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

FEZ2_MOUSE
NC score	0.067290 (rank : 1790)	θ value	θ > 10 (rank : 1670)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

CCDC3_HUMAN
NC score	0.067288 (rank : 1791)	θ value	θ > 10 (rank : 1488)
Query Neighborhood Hits	1371	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BQI4	Gene names	CCDC3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

E41L2_HUMAN
NC score	0.067106 (rank : 1792)	θ value	θ > 10 (rank : 1610)
Query Neighborhood Hits	1371	Target Neighborhood Hits	287	Shared Neighborhood Hits	150
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

STX2_HUMAN
NC score	0.067065 (rank : 1793)	θ value	θ > 10 (rank : 2211)
Query Neighborhood Hits	1371	Target Neighborhood Hits	158	Shared Neighborhood Hits	119
SwissProt Accessions	P32856, Q86VW8	Gene names	STX2, EPIM
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

GCFC_HUMAN
NC score	0.067046 (rank : 1794)	θ value	0.365318 (rank : 907)
Query Neighborhood Hits	1371	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y5B6, Q9NYQ0	Gene names	GCFC, C21orf66
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor homolog.

SAMN1_HUMAN
NC score	0.066977 (rank : 1795)	θ value	θ > 10 (rank : 2114)
Query Neighborhood Hits	1371	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

KIF2B_HUMAN
NC score	0.066746 (rank : 1796)	θ value	θ > 10 (rank : 1822)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N4N8, Q96MA2, Q9BXG6	Gene names	KIF2B
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF2B.

CYLC2_HUMAN
NC score	0.066687 (rank : 1797)	θ value	θ > 10 (rank : 1564)
Query Neighborhood Hits	1371	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

KIF2B_MOUSE
NC score	0.066673 (rank : 1798)	θ value	θ > 10 (rank : 1823)
Query Neighborhood Hits	1371	Target Neighborhood Hits	63	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C0N1	Gene names	Kif2b
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF2B.

FUT8_HUMAN
NC score	0.066541 (rank : 1799)	θ value	θ > 10 (rank : 1679)
Query Neighborhood Hits	1371	Target Neighborhood Hits	67	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYC5, O00235, Q9BYC6, Q9P2U5, Q9P2U6	Gene names	FUT8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

PRP4B_MOUSE
NC score	0.066319 (rank : 1800)	θ value	4.03905 (rank : 1218)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1040	Shared Neighborhood Hits	220
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

ZFY19_MOUSE
NC score	0.066300 (rank : 1801)	θ value	θ > 10 (rank : 2348)
Query Neighborhood Hits	1371	Target Neighborhood Hits	143	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

OTU6A_HUMAN
NC score	0.066234 (rank : 1802)	θ value	θ > 10 (rank : 1997)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q7L8S5	Gene names	OTUD6A
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6A.

LCP2_HUMAN
NC score	0.066154 (rank : 1803)	θ value	θ > 10 (rank : 1874)
Query Neighborhood Hits	1371	Target Neighborhood Hits	531	Shared Neighborhood Hits	99
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CE005_HUMAN
NC score	0.065681 (rank : 1804)	θ value	θ > 10 (rank : 1499)
Query Neighborhood Hits	1371	Target Neighborhood Hits	213	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

BRDT_HUMAN
NC score	0.065598 (rank : 1805)	θ value	θ > 10 (rank : 1462)
Query Neighborhood Hits	1371	Target Neighborhood Hits	280	Shared Neighborhood Hits	135
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

LAD1_MOUSE
NC score	0.065589 (rank : 1806)	θ value	θ > 10 (rank : 1856)
Query Neighborhood Hits	1371	Target Neighborhood Hits	391	Shared Neighborhood Hits	125
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

NCOR1_HUMAN
NC score	0.065494 (rank : 1807)	θ value	θ > 10 (rank : 1961)
Query Neighborhood Hits	1371	Target Neighborhood Hits	577	Shared Neighborhood Hits	171
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

ZFY19_HUMAN
NC score	0.065421 (rank : 1808)	θ value	θ > 10 (rank : 2347)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	53
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

CPNE3_MOUSE
NC score	0.065351 (rank : 1809)	θ value	0.21417 (rank : 841)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

JIP2_MOUSE
NC score	0.065327 (rank : 1810)	θ value	θ > 10 (rank : 1763)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

GRB7_HUMAN
NC score	0.065278 (rank : 1811)	θ value	θ > 10 (rank : 1709)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	61
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

ILK_MOUSE
NC score	0.065171 (rank : 1812)	θ value	θ > 10 (rank : 1741)
Query Neighborhood Hits	1371	Target Neighborhood Hits	858	Shared Neighborhood Hits	113
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

STYK1_MOUSE
NC score	0.065081 (rank : 1813)	θ value	θ > 10 (rank : 2219)
Query Neighborhood Hits	1371	Target Neighborhood Hits	779	Shared Neighborhood Hits	92
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

TLK1_HUMAN
NC score	0.064942 (rank : 1814)	θ value	θ > 10 (rank : 2272)
Query Neighborhood Hits	1371	Target Neighborhood Hits	967	Shared Neighborhood Hits	234
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

ILK1_HUMAN
NC score	0.064900 (rank : 1815)	θ value	θ > 10 (rank : 1739)
Query Neighborhood Hits	1371	Target Neighborhood Hits	857	Shared Neighborhood Hits	113
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

LAMB2_MOUSE
NC score	0.064833 (rank : 1816)	θ value	θ > 10 (rank : 1865)
Query Neighborhood Hits	1371	Target Neighborhood Hits	722	Shared Neighborhood Hits	239
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

XRCC4_HUMAN
NC score	0.064438 (rank : 1817)	θ value	θ > 10 (rank : 2338)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

GP137_HUMAN
NC score	0.064426 (rank : 1818)	θ value	θ > 10 (rank : 1702)
Query Neighborhood Hits	1371	Target Neighborhood Hits	119	Shared Neighborhood Hits	68
SwissProt Accessions	Q14444, Q15074	Gene names	M11S1, GPIP137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI) (Membrane component chromosome 11 surface marker 1).

TAK1L_HUMAN
NC score	0.064389 (rank : 1819)	θ value	θ > 10 (rank : 2250)
Query Neighborhood Hits	1371	Target Neighborhood Hits	141	Shared Neighborhood Hits	97
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

ILK2_HUMAN
NC score	0.064337 (rank : 1820)	θ value	θ > 10 (rank : 1740)
Query Neighborhood Hits	1371	Target Neighborhood Hits	848	Shared Neighborhood Hits	113
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

TRI62_MOUSE
NC score	0.064134 (rank : 1821)	θ value	0.0961366 (rank : 802)
Query Neighborhood Hits	1371	Target Neighborhood Hits	478	Shared Neighborhood Hits	221
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

STYK1_HUMAN
NC score	0.064019 (rank : 1822)	θ value	θ > 10 (rank : 2218)
Query Neighborhood Hits	1371	Target Neighborhood Hits	786	Shared Neighborhood Hits	94
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

RRP5_HUMAN
NC score	0.063928 (rank : 1823)	θ value	6.88961 (rank : 1315)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	121
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

ING3_HUMAN
NC score	0.063926 (rank : 1824)	θ value	3.0926 (rank : 1175)
Query Neighborhood Hits	1371	Target Neighborhood Hits	178	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ANR15_HUMAN
NC score	0.063926 (rank : 1825)	θ value	θ > 10 (rank : 1411)
Query Neighborhood Hits	1371	Target Neighborhood Hits	478	Shared Neighborhood Hits	153
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

TLK1_MOUSE
NC score	0.063796 (rank : 1826)	θ value	θ > 10 (rank : 2273)
Query Neighborhood Hits	1371	Target Neighborhood Hits	947	Shared Neighborhood Hits	215
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

RASF7_HUMAN
NC score	0.063653 (rank : 1827)	θ value	θ > 10 (rank : 2063)
Query Neighborhood Hits	1371	Target Neighborhood Hits	96	Shared Neighborhood Hits	54
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

C8AP2_MOUSE
NC score	0.063600 (rank : 1828)	θ value	θ > 10 (rank : 1467)
Query Neighborhood Hits	1371	Target Neighborhood Hits	405	Shared Neighborhood Hits	153
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

IKKB_HUMAN
NC score	0.063488 (rank : 1829)	θ value	θ > 10 (rank : 1738)
Query Neighborhood Hits	1371	Target Neighborhood Hits	980	Shared Neighborhood Hits	210
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

CP045_MOUSE
NC score	0.063483 (rank : 1830)	θ value	θ > 10 (rank : 1546)
Query Neighborhood Hits	1371	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R1Y2, Q3UVX0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf45 homolog.

APS_MOUSE
NC score	0.063248 (rank : 1831)	θ value	θ > 10 (rank : 1425)
Query Neighborhood Hits	1371	Target Neighborhood Hits	134	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

PRP4B_HUMAN
NC score	0.063219 (rank : 1832)	θ value	2.36792 (rank : 1152)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1030	Shared Neighborhood Hits	204
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

MILK2_HUMAN
NC score	0.063174 (rank : 1833)	θ value	θ > 10 (rank : 1910)
Query Neighborhood Hits	1371	Target Neighborhood Hits	457	Shared Neighborhood Hits	136
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

NU214_HUMAN
NC score	0.063173 (rank : 1834)	θ value	θ > 10 (rank : 1989)
Query Neighborhood Hits	1371	Target Neighborhood Hits	657	Shared Neighborhood Hits	137
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SOCS7_MOUSE
NC score	0.062986 (rank : 1835)	θ value	θ > 10 (rank : 2171)
Query Neighborhood Hits	1371	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

TRI44_HUMAN
NC score	0.062976 (rank : 1836)	θ value	θ > 10 (rank : 2295)
Query Neighborhood Hits	1371	Target Neighborhood Hits	393	Shared Neighborhood Hits	144
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

MSRE_MOUSE
NC score	0.062905 (rank : 1837)	θ value	θ > 10 (rank : 1927)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	137
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

NIP30_HUMAN
NC score	0.062787 (rank : 1838)	θ value	θ > 10 (rank : 1970)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	73
SwissProt Accessions	Q9GZU8	Gene names	NIP30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

CA049_HUMAN
NC score	0.062780 (rank : 1839)	θ value	θ > 10 (rank : 1468)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	56
SwissProt Accessions	Q5T0J7, Q5T0J9, Q8IYU6, Q8N7Z1, Q8NA15, Q9H0Q7	Gene names	C1orf49
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49.

LUC7L_MOUSE
NC score	0.062716 (rank : 1840)	θ value	θ > 10 (rank : 1890)
Query Neighborhood Hits	1371	Target Neighborhood Hits	111	Shared Neighborhood Hits	78
SwissProt Accessions	Q9CYI4, Q8K247, Q9CWM1	Gene names	Luc7l
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 1.

RIMS3_HUMAN
NC score	0.062692 (rank : 1841)	θ value	θ > 10 (rank : 2083)
Query Neighborhood Hits	1371	Target Neighborhood Hits	66	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

TR150_MOUSE
NC score	0.062689 (rank : 1842)	θ value	1.81305 (rank : 1115)
Query Neighborhood Hits	1371	Target Neighborhood Hits	468	Shared Neighborhood Hits	147
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

PTN11_HUMAN
NC score	0.062579 (rank : 1843)	θ value	θ > 10 (rank : 2047)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	78
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

MNT_HUMAN
NC score	0.062558 (rank : 1844)	θ value	1.38821 (rank : 1059)
Query Neighborhood Hits	1371	Target Neighborhood Hits	496	Shared Neighborhood Hits	116
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SH22A_MOUSE
NC score	0.062537 (rank : 1845)	θ value	θ > 10 (rank : 2139)
Query Neighborhood Hits	1371	Target Neighborhood Hits	179	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

CHMP5_MOUSE
NC score	0.062494 (rank : 1846)	θ value	θ > 10 (rank : 1520)
Query Neighborhood Hits	1371	Target Neighborhood Hits	95	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D7S9, Q3UI64	Gene names	Chmp5, Snf7dc2
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2).

PTN11_MOUSE
NC score	0.062436 (rank : 1847)	θ value	θ > 10 (rank : 2048)
Query Neighborhood Hits	1371	Target Neighborhood Hits	227	Shared Neighborhood Hits	77
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

RFC1_MOUSE
NC score	0.062385 (rank : 1848)	θ value	θ > 10 (rank : 2073)
Query Neighborhood Hits	1371	Target Neighborhood Hits	290	Shared Neighborhood Hits	115
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

MTSS1_MOUSE
NC score	0.062201 (rank : 1849)	θ value	θ > 10 (rank : 1931)
Query Neighborhood Hits	1371	Target Neighborhood Hits	592	Shared Neighborhood Hits	127
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

TRI35_MOUSE
NC score	0.062171 (rank : 1850)	θ value	0.163984 (rank : 837)
Query Neighborhood Hits	1371	Target Neighborhood Hits	465	Shared Neighborhood Hits	187
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

BLNK_MOUSE
NC score	0.062166 (rank : 1851)	θ value	θ > 10 (rank : 1454)
Query Neighborhood Hits	1371	Target Neighborhood Hits	296	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

SAMN1_MOUSE
NC score	0.062011 (rank : 1852)	θ value	θ > 10 (rank : 2115)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	45
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

NEK1_HUMAN
NC score	0.061974 (rank : 1853)	θ value	θ > 10 (rank : 1967)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1129	Shared Neighborhood Hits	262
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

YTDC1_HUMAN
NC score	0.061882 (rank : 1854)	θ value	θ > 10 (rank : 2341)
Query Neighborhood Hits	1371	Target Neighborhood Hits	458	Shared Neighborhood Hits	143
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

COG7_HUMAN
NC score	0.061876 (rank : 1855)	θ value	θ > 10 (rank : 1543)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	80
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

CL004_HUMAN
NC score	0.061822 (rank : 1856)	θ value	θ > 10 (rank : 1526)
Query Neighborhood Hits	1371	Target Neighborhood Hits	115	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NQ89, Q6MZH5	Gene names	C12orf4
Domain Architecture	No domain graphic available
Description	Protein C12orf4.

SH2D3_MOUSE
NC score	0.061478 (rank : 1857)	θ value	θ > 10 (rank : 2141)
Query Neighborhood Hits	1371	Target Neighborhood Hits	174	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

DMPK_MOUSE
NC score	0.061466 (rank : 1858)	θ value	5.27518 (rank : 1241)
Query Neighborhood Hits	1371	Target Neighborhood Hits	908	Shared Neighborhood Hits	156
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

P3C2A_HUMAN
NC score	0.061462 (rank : 1859)	θ value	θ > 10 (rank : 2003)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	72
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

IF31_HUMAN
NC score	0.061422 (rank : 1860)	θ value	θ > 10 (rank : 1734)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

GRB10_MOUSE
NC score	0.061198 (rank : 1861)	θ value	θ > 10 (rank : 1706)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

CPLX2_HUMAN
NC score	0.061138 (rank : 1862)	θ value	θ > 10 (rank : 1547)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PUV4, O09056, Q13329, Q28184, Q52M15, Q64386	Gene names	CPLX2
Domain Architecture	No domain graphic available
Description	Complexin-2 (Complexin II) (CPX II) (Synaphin-1).

CPLX2_MOUSE
NC score	0.061138 (rank : 1863)	θ value	θ > 10 (rank : 1548)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	76
SwissProt Accessions	P84086, O09056, Q13329, Q28184, Q32KK4, Q64386	Gene names	Cplx2
Domain Architecture	No domain graphic available
Description	Complexin-2 (Complexin II) (CPX II) (Synaphin-1) (921-L).

OPHN1_HUMAN
NC score	0.061093 (rank : 1864)	θ value	1.81305 (rank : 1105)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	75
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

UBXD8_MOUSE
NC score	0.060918 (rank : 1865)	θ value	θ > 10 (rank : 2308)
Query Neighborhood Hits	1371	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	Q3TDN2, Q3U9W2, Q80TP7, Q80W42	Gene names	Ubxd8, Kiaa0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8.

RGS3_HUMAN
NC score	0.060774 (rank : 1866)	θ value	θ > 10 (rank : 2075)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1375	Shared Neighborhood Hits	203
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GRB10_HUMAN
NC score	0.060759 (rank : 1867)	θ value	θ > 10 (rank : 1705)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	57
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

DIAP3_MOUSE
NC score	0.060741 (rank : 1868)	θ value	1.38821 (rank : 1049)
Query Neighborhood Hits	1371	Target Neighborhood Hits	221	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

TBK1_MOUSE
NC score	0.060689 (rank : 1869)	θ value	θ > 10 (rank : 2259)
Query Neighborhood Hits	1371	Target Neighborhood Hits	893	Shared Neighborhood Hits	177
SwissProt Accessions	Q9WUN2, Q9CT90, Q9DC03	Gene names	Tbk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K).

FAK2_MOUSE
NC score	0.060664 (rank : 1870)	θ value	8.99809 (rank : 1330)
Query Neighborhood Hits	1371	Target Neighborhood Hits	851	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

XBP1_HUMAN
NC score	0.060629 (rank : 1871)	θ value	θ > 10 (rank : 2335)
Query Neighborhood Hits	1371	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

DMPK_HUMAN
NC score	0.060592 (rank : 1872)	θ value	θ > 10 (rank : 1592)
Query Neighborhood Hits	1371	Target Neighborhood Hits	944	Shared Neighborhood Hits	172
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

P3C2A_MOUSE
NC score	0.060442 (rank : 1873)	θ value	θ > 10 (rank : 2004)
Query Neighborhood Hits	1371	Target Neighborhood Hits	181	Shared Neighborhood Hits	72
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

NCOR1_MOUSE
NC score	0.060423 (rank : 1874)	θ value	θ > 10 (rank : 1962)
Query Neighborhood Hits	1371	Target Neighborhood Hits	521	Shared Neighborhood Hits	157
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

RAF1_MOUSE
NC score	0.060416 (rank : 1875)	θ value	θ > 10 (rank : 2058)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	111
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

LYAR_HUMAN
NC score	0.060311 (rank : 1876)	θ value	θ > 10 (rank : 1891)
Query Neighborhood Hits	1371	Target Neighborhood Hits	155	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NX58, Q6FI78, Q9NYS1	Gene names	LYAR
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

CE005_MOUSE
NC score	0.060282 (rank : 1877)	θ value	θ > 10 (rank : 1500)
Query Neighborhood Hits	1371	Target Neighborhood Hits	238	Shared Neighborhood Hits	119
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

FEZ1_HUMAN
NC score	0.060229 (rank : 1878)	θ value	θ > 10 (rank : 1669)
Query Neighborhood Hits	1371	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	Q99689, O00679, O00728, Q6IBI7	Gene names	FEZ1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

FAM9B_HUMAN
NC score	0.060219 (rank : 1879)	θ value	θ > 10 (rank : 1663)
Query Neighborhood Hits	1371	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZU0	Gene names	FAM9B
Domain Architecture	No domain graphic available
Description	Protein FAM9B.

RIMS3_MOUSE
NC score	0.060218 (rank : 1880)	θ value	θ > 10 (rank : 2084)
Query Neighborhood Hits	1371	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

HTSF1_MOUSE
NC score	0.060150 (rank : 1881)	θ value	θ > 10 (rank : 1733)
Query Neighborhood Hits	1371	Target Neighborhood Hits	425	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

FAK2_HUMAN
NC score	0.060148 (rank : 1882)	θ value	θ > 10 (rank : 1661)
Query Neighborhood Hits	1371	Target Neighborhood Hits	847	Shared Neighborhood Hits	110
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

APLP2_HUMAN
NC score	0.060139 (rank : 1883)	θ value	2.36792 (rank : 1119)
Query Neighborhood Hits	1371	Target Neighborhood Hits	193	Shared Neighborhood Hits	109
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

RAF1_HUMAN
NC score	0.060126 (rank : 1884)	θ value	θ > 10 (rank : 2057)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	111
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

VINC_MOUSE
NC score	0.060110 (rank : 1885)	θ value	θ > 10 (rank : 2325)
Query Neighborhood Hits	1371	Target Neighborhood Hits	135	Shared Neighborhood Hits	79
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

DIAP3_HUMAN
NC score	0.059981 (rank : 1886)	θ value	0.0252991 (rank : 674)
Query Neighborhood Hits	1371	Target Neighborhood Hits	209	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

EVG1_MOUSE
NC score	0.059939 (rank : 1887)	θ value	0.0563607 (rank : 729)
Query Neighborhood Hits	1371	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D9S1	Gene names
Domain Architecture
Description	UPF0193 protein EVG1 homolog.

SEMG2_HUMAN
NC score	0.059909 (rank : 1888)	θ value	θ > 10 (rank : 2125)
Query Neighborhood Hits	1371	Target Neighborhood Hits	251	Shared Neighborhood Hits	86
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

BCAS2_HUMAN
NC score	0.059907 (rank : 1889)	θ value	θ > 10 (rank : 1443)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	66
SwissProt Accessions	O75934, Q6FGS0	Gene names	BCAS2, DAM1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 2 (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27).

BCAS2_MOUSE
NC score	0.059907 (rank : 1890)	θ value	θ > 10 (rank : 1444)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D287, Q3TKJ5, Q91YX8, Q9D2U4, Q9DAI0	Gene names	Bcas2, Dam1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 2 homolog (DNA amplified in mammary carcinoma 1 protein).

FA76A_HUMAN
NC score	0.059853 (rank : 1891)	θ value	θ > 10 (rank : 1655)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TAV0, O95565, O95566, Q8N7J5	Gene names	FAM76A
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

AATK_MOUSE
NC score	0.059842 (rank : 1892)	θ value	θ > 10 (rank : 1377)
Query Neighborhood Hits	1371	Target Neighborhood Hits	942	Shared Neighborhood Hits	110
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

DACH2_HUMAN
NC score	0.059489 (rank : 1893)	θ value	θ > 10 (rank : 1568)
Query Neighborhood Hits	1371	Target Neighborhood Hits	122	Shared Neighborhood Hits	100
SwissProt Accessions	Q96NX9, Q8NAY3, Q8ND17, Q96N55	Gene names	DACH2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

IF4G3_HUMAN
NC score	0.059332 (rank : 1894)	θ value	0.163984 (rank : 830)
Query Neighborhood Hits	1371	Target Neighborhood Hits	247	Shared Neighborhood Hits	99
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

ZW10_HUMAN
NC score	0.059316 (rank : 1895)	θ value	8.99809 (rank : 1371)
Query Neighborhood Hits	1371	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	O43264	Gene names	ZW10
Domain Architecture
Description	Centromere/kinetochore protein zw10 homolog.

KGP2_HUMAN
NC score	0.059300 (rank : 1896)	θ value	4.03905 (rank : 1209)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1023	Shared Neighborhood Hits	209
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

FYV1_HUMAN
NC score	0.059281 (rank : 1897)	θ value	θ > 10 (rank : 1682)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

OPHN1_MOUSE
NC score	0.059228 (rank : 1898)	θ value	θ > 10 (rank : 1996)
Query Neighborhood Hits	1371	Target Neighborhood Hits	174	Shared Neighborhood Hits	75
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

ALK_HUMAN
NC score	0.059219 (rank : 1899)	θ value	θ > 10 (rank : 1397)
Query Neighborhood Hits	1371	Target Neighborhood Hits	795	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
NC score	0.059194 (rank : 1900)	θ value	θ > 10 (rank : 1398)
Query Neighborhood Hits	1371	Target Neighborhood Hits	811	Shared Neighborhood Hits	99
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

DJC17_MOUSE
NC score	0.058923 (rank : 1901)	θ value	θ > 10 (rank : 1588)
Query Neighborhood Hits	1371	Target Neighborhood Hits	217	Shared Neighborhood Hits	121
SwissProt Accessions	Q91WT4, Q8C5R1	Gene names	Dnajc17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

UTP11_MOUSE
NC score	0.058913 (rank : 1902)	θ value	5.27518 (rank : 1275)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CZJ1, Q3UI21, Q9CVB5	Gene names	Utp11l
Domain Architecture
Description	Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA- associated protein 11) (UTP11-like protein).

CP045_HUMAN
NC score	0.058791 (rank : 1903)	θ value	θ > 10 (rank : 1545)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	58
SwissProt Accessions	Q96MC5, O00223, O75769, Q8IZ36, Q96H25	Gene names	C16orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf45.

DMP1_HUMAN
NC score	0.058740 (rank : 1904)	θ value	1.06291 (rank : 1011)
Query Neighborhood Hits	1371	Target Neighborhood Hits	491	Shared Neighborhood Hits	118
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TRI34_HUMAN
NC score	0.058698 (rank : 1905)	θ value	5.27518 (rank : 1270)
Query Neighborhood Hits	1371	Target Neighborhood Hits	416	Shared Neighborhood Hits	189
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

FYV1_MOUSE
NC score	0.058689 (rank : 1906)	θ value	θ > 10 (rank : 1683)
Query Neighborhood Hits	1371	Target Neighborhood Hits	191	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

IQGA2_HUMAN
NC score	0.058675 (rank : 1907)	θ value	θ > 10 (rank : 1748)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

MLTK_MOUSE
NC score	0.058668 (rank : 1908)	θ value	θ > 10 (rank : 1916)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

CL004_MOUSE
NC score	0.058616 (rank : 1909)	θ value	θ > 10 (rank : 1527)
Query Neighborhood Hits	1371	Target Neighborhood Hits	119	Shared Neighborhood Hits	81
SwissProt Accessions	Q91YN0, Q3UVK4	Gene names	D6Wsu163e
Domain Architecture	No domain graphic available
Description	Protein C12orf4 homolog.

TRI25_HUMAN
NC score	0.058610 (rank : 1910)	θ value	θ > 10 (rank : 2292)
Query Neighborhood Hits	1371	Target Neighborhood Hits	472	Shared Neighborhood Hits	179
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

ROS_HUMAN
NC score	0.058539 (rank : 1911)	θ value	θ > 10 (rank : 2103)
Query Neighborhood Hits	1371	Target Neighborhood Hits	907	Shared Neighborhood Hits	97
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SMCA4_HUMAN
NC score	0.058469 (rank : 1912)	θ value	θ > 10 (rank : 2158)
Query Neighborhood Hits	1371	Target Neighborhood Hits	597	Shared Neighborhood Hits	201
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

DACH2_MOUSE
NC score	0.058435 (rank : 1913)	θ value	θ > 10 (rank : 1569)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	98
SwissProt Accessions	Q925Q8, Q8BMA0	Gene names	Dach2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

USBP1_MOUSE
NC score	0.058424 (rank : 1914)	θ value	θ > 10 (rank : 2314)
Query Neighborhood Hits	1371	Target Neighborhood Hits	115	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R370	Gene names	Ushbp1
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1).

VGF_HUMAN
NC score	0.058317 (rank : 1915)	θ value	θ > 10 (rank : 2323)
Query Neighborhood Hits	1371	Target Neighborhood Hits	167	Shared Neighborhood Hits	54
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

ONCO_HUMAN
NC score	0.058296 (rank : 1916)	θ value	0.813845 (rank : 990)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

MLTK_HUMAN
NC score	0.058275 (rank : 1917)	θ value	θ > 10 (rank : 1915)
Query Neighborhood Hits	1371	Target Neighborhood Hits	911	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

ONCO_MOUSE
NC score	0.058269 (rank : 1918)	θ value	1.38821 (rank : 1061)
Query Neighborhood Hits	1371	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	P51879, Q62004	Gene names	Ocm
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

NARG1_HUMAN
NC score	0.058247 (rank : 1919)	θ value	0.47712 (rank : 944)
Query Neighborhood Hits	1371	Target Neighborhood Hits	114	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

LAMA5_HUMAN
NC score	0.058242 (rank : 1920)	θ value	θ > 10 (rank : 1863)
Query Neighborhood Hits	1371	Target Neighborhood Hits	976	Shared Neighborhood Hits	262
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

STX5_HUMAN
NC score	0.058210 (rank : 1921)	θ value	θ > 10 (rank : 2214)
Query Neighborhood Hits	1371	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	Q13190, Q5U0D4, Q7Z3T6, Q9BUG1	Gene names	STX5, STX5A
Domain Architecture
Description	Syntaxin-5.

LTK_MOUSE
NC score	0.058077 (rank : 1922)	θ value	θ > 10 (rank : 1888)
Query Neighborhood Hits	1371	Target Neighborhood Hits	770	Shared Neighborhood Hits	96
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

BRAF1_HUMAN
NC score	0.058054 (rank : 1923)	θ value	θ > 10 (rank : 1458)
Query Neighborhood Hits	1371	Target Neighborhood Hits	883	Shared Neighborhood Hits	111
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

CALL5_HUMAN
NC score	0.058039 (rank : 1924)	θ value	0.0736092 (rank : 746)
Query Neighborhood Hits	1371	Target Neighborhood Hits	231	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CK035_HUMAN
NC score	0.058013 (rank : 1925)	θ value	θ > 10 (rank : 1524)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IXW0	Gene names	C11orf35
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35.

AATK_HUMAN
NC score	0.057950 (rank : 1926)	θ value	θ > 10 (rank : 1376)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1243	Shared Neighborhood Hits	140
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

TNK1_MOUSE
NC score	0.057928 (rank : 1927)	θ value	θ > 10 (rank : 2283)
Query Neighborhood Hits	1371	Target Neighborhood Hits	806	Shared Neighborhood Hits	99
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

ZC11A_MOUSE
NC score	0.057919 (rank : 1928)	θ value	θ > 10 (rank : 2344)
Query Neighborhood Hits	1371	Target Neighborhood Hits	216	Shared Neighborhood Hits	100
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

TNI3K_MOUSE
NC score	0.057903 (rank : 1929)	θ value	θ > 10 (rank : 2281)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1079	Shared Neighborhood Hits	124
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CLCA_MOUSE
NC score	0.057893 (rank : 1930)	θ value	θ > 10 (rank : 1532)
Query Neighborhood Hits	1371	Target Neighborhood Hits	106	Shared Neighborhood Hits	84
SwissProt Accessions	O08585	Gene names	Clta
Domain Architecture
Description	Clathrin light chain A (Lca).

KGP2_MOUSE
NC score	0.057886 (rank : 1931)	θ value	θ > 10 (rank : 1804)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1029	Shared Neighborhood Hits	220
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

NARG1_MOUSE
NC score	0.057829 (rank : 1932)	θ value	0.47712 (rank : 945)
Query Neighborhood Hits	1371	Target Neighborhood Hits	111	Shared Neighborhood Hits	61
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

SOX6_HUMAN
NC score	0.057696 (rank : 1933)	θ value	θ > 10 (rank : 2175)
Query Neighborhood Hits	1371	Target Neighborhood Hits	332	Shared Neighborhood Hits	143
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
NC score	0.057669 (rank : 1934)	θ value	θ > 10 (rank : 2176)
Query Neighborhood Hits	1371	Target Neighborhood Hits	341	Shared Neighborhood Hits	143
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

TNI3K_HUMAN
NC score	0.057640 (rank : 1935)	θ value	θ > 10 (rank : 2280)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1084	Shared Neighborhood Hits	126
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANKK1_MOUSE
NC score	0.057607 (rank : 1936)	θ value	θ > 10 (rank : 1409)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1072	Shared Neighborhood Hits	126
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

SMG1_HUMAN
NC score	0.057562 (rank : 1937)	θ value	θ > 10 (rank : 2159)
Query Neighborhood Hits	1371	Target Neighborhood Hits	231	Shared Neighborhood Hits	121
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SEMG1_HUMAN
NC score	0.057555 (rank : 1938)	θ value	2.36792 (rank : 1157)
Query Neighborhood Hits	1371	Target Neighborhood Hits	200	Shared Neighborhood Hits	71
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

EPIPL_MOUSE
NC score	0.057396 (rank : 1939)	θ value	2.36792 (rank : 1135)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R0W0	Gene names	Eppk1
Domain Architecture
Description	Epiplakin.

NMI_HUMAN
NC score	0.057239 (rank : 1940)	θ value	θ > 10 (rank : 1972)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q13287, Q53TI8, Q9BVE5	Gene names	NMI
Domain Architecture
Description	N-myc-interactor (Nmi) (N-myc and STAT interactor).

KPCE_MOUSE
NC score	0.057216 (rank : 1941)	θ value	θ > 10 (rank : 1838)
Query Neighborhood Hits	1371	Target Neighborhood Hits	906	Shared Neighborhood Hits	127
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

UBXD8_HUMAN
NC score	0.057188 (rank : 1942)	θ value	θ > 10 (rank : 2307)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	93
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

KPCE_HUMAN
NC score	0.057159 (rank : 1943)	θ value	θ > 10 (rank : 1837)
Query Neighborhood Hits	1371	Target Neighborhood Hits	906	Shared Neighborhood Hits	128
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

ARAF_MOUSE
NC score	0.057056 (rank : 1944)	θ value	θ > 10 (rank : 1428)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	107
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

FAK1_HUMAN
NC score	0.057034 (rank : 1945)	θ value	θ > 10 (rank : 1659)
Query Neighborhood Hits	1371	Target Neighborhood Hits	850	Shared Neighborhood Hits	101
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

HSH2D_MOUSE
NC score	0.056970 (rank : 1946)	θ value	θ > 10 (rank : 1730)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

LRMP_MOUSE
NC score	0.056956 (rank : 1947)	θ value	θ > 10 (rank : 1885)
Query Neighborhood Hits	1371	Target Neighborhood Hits	120	Shared Neighborhood Hits	79
SwissProt Accessions	Q60664, Q7TMU8	Gene names	Lrmp, Jaw1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

LTK_HUMAN
NC score	0.056840 (rank : 1948)	θ value	θ > 10 (rank : 1887)
Query Neighborhood Hits	1371	Target Neighborhood Hits	774	Shared Neighborhood Hits	95
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

TRI15_HUMAN
NC score	0.056836 (rank : 1949)	θ value	θ > 10 (rank : 2290)
Query Neighborhood Hits	1371	Target Neighborhood Hits	395	Shared Neighborhood Hits	172
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

CPNE3_HUMAN
NC score	0.056788 (rank : 1950)	θ value	2.36792 (rank : 1128)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	62
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

ANKK1_HUMAN
NC score	0.056755 (rank : 1951)	θ value	θ > 10 (rank : 1408)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1075	Shared Neighborhood Hits	127
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

NIP30_MOUSE
NC score	0.056729 (rank : 1952)	θ value	θ > 10 (rank : 1971)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	Q91WE2, Q8R0C9	Gene names	Nip30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

M3K7_MOUSE
NC score	0.056659 (rank : 1953)	θ value	θ > 10 (rank : 1896)
Query Neighborhood Hits	1371	Target Neighborhood Hits	892	Shared Neighborhood Hits	136
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

TNK1_HUMAN
NC score	0.056657 (rank : 1954)	θ value	θ > 10 (rank : 2282)
Query Neighborhood Hits	1371	Target Neighborhood Hits	815	Shared Neighborhood Hits	99
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

ARAF_HUMAN
NC score	0.056653 (rank : 1955)	θ value	θ > 10 (rank : 1427)
Query Neighborhood Hits	1371	Target Neighborhood Hits	924	Shared Neighborhood Hits	111
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

SH2D3_HUMAN
NC score	0.056608 (rank : 1956)	θ value	θ > 10 (rank : 2140)
Query Neighborhood Hits	1371	Target Neighborhood Hits	188	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

FAK1_MOUSE
NC score	0.056587 (rank : 1957)	θ value	θ > 10 (rank : 1660)
Query Neighborhood Hits	1371	Target Neighborhood Hits	850	Shared Neighborhood Hits	97
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

SRRM2_HUMAN
NC score	0.056570 (rank : 1958)	θ value	θ > 10 (rank : 2189)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1296	Shared Neighborhood Hits	181
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DDR1_HUMAN
NC score	0.056465 (rank : 1959)	θ value	θ > 10 (rank : 1573)
Query Neighborhood Hits	1371	Target Neighborhood Hits	819	Shared Neighborhood Hits	93
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

M3K7_HUMAN
NC score	0.056414 (rank : 1960)	θ value	θ > 10 (rank : 1895)
Query Neighborhood Hits	1371	Target Neighborhood Hits	892	Shared Neighborhood Hits	133
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

ATIF1_MOUSE
NC score	0.056364 (rank : 1961)	θ value	θ > 10 (rank : 1432)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	O35143	Gene names	Atpif1, Atpi, If1
Domain Architecture
Description	ATPase inhibitor, mitochondrial precursor.

SCG2_HUMAN
NC score	0.056251 (rank : 1962)	θ value	θ > 10 (rank : 2116)
Query Neighborhood Hits	1371	Target Neighborhood Hits	190	Shared Neighborhood Hits	88
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

DDR1_MOUSE
NC score	0.056142 (rank : 1963)	θ value	θ > 10 (rank : 1574)
Query Neighborhood Hits	1371	Target Neighborhood Hits	818	Shared Neighborhood Hits	93
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

CD209_HUMAN
NC score	0.056086 (rank : 1964)	θ value	0.813845 (rank : 977)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NNX6, Q96QP7, Q96QP8, Q96QP9, Q96QQ0, Q96QQ1, Q96QQ2, Q96QQ3, Q96QQ4, Q96QQ5, Q96QQ6, Q96QQ7, Q96QQ8	Gene names	CD209, CLEC4L
Domain Architecture
Description	CD209 antigen (Dendritic cell-specific ICAM-3-grabbing nonintegrin 1) (DC-SIGN1) (DC-SIGN) (C-type lectin domain family 4 member L).

AGGF1_HUMAN
NC score	0.056064 (rank : 1965)	θ value	θ > 10 (rank : 1391)
Query Neighborhood Hits	1371	Target Neighborhood Hits	271	Shared Neighborhood Hits	119
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

TITIN_HUMAN
NC score	0.056015 (rank : 1966)	θ value	θ > 10 (rank : 2271)
Query Neighborhood Hits	1371	Target Neighborhood Hits	2923	Shared Neighborhood Hits	486
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

PLSL_MOUSE
NC score	0.055993 (rank : 1967)	θ value	6.88961 (rank : 1311)
Query Neighborhood Hits	1371	Target Neighborhood Hits	170	Shared Neighborhood Hits	64
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

K0100_HUMAN
NC score	0.055983 (rank : 1968)	θ value	θ > 10 (rank : 1766)
Query Neighborhood Hits	1371	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	Q14667, Q3SYN5, Q49A07, Q5H9T4, Q6WG74, Q6ZP51, Q96HH8	Gene names	KIAA0100, BCOX1
Domain Architecture	No domain graphic available
Description	UPF0378 family protein KIAA0100 precursor (Breast cancer overexpressed gene 1 protein) (Antigen MLAA-22).

LAMB2_HUMAN
NC score	0.055941 (rank : 1969)	θ value	θ > 10 (rank : 1864)
Query Neighborhood Hits	1371	Target Neighborhood Hits	692	Shared Neighborhood Hits	187
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

SH22A_HUMAN
NC score	0.055859 (rank : 1970)	θ value	θ > 10 (rank : 2138)
Query Neighborhood Hits	1371	Target Neighborhood Hits	144	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

ERBB4_HUMAN
NC score	0.055765 (rank : 1971)	θ value	θ > 10 (rank : 1646)
Query Neighborhood Hits	1371	Target Neighborhood Hits	910	Shared Neighborhood Hits	100
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

TTC17_HUMAN
NC score	0.055749 (rank : 1972)	θ value	θ > 10 (rank : 2300)
Query Neighborhood Hits	1371	Target Neighborhood Hits	118	Shared Neighborhood Hits	53
SwissProt Accessions	Q96AE7	Gene names	TTC17
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 17 (TPR repeat protein 17).

SRRM1_MOUSE
NC score	0.055549 (rank : 1973)	θ value	θ > 10 (rank : 2188)
Query Neighborhood Hits	1371	Target Neighborhood Hits	966	Shared Neighborhood Hits	164
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ANR38_HUMAN
NC score	0.055516 (rank : 1974)	θ value	θ > 10 (rank : 1412)
Query Neighborhood Hits	1371	Target Neighborhood Hits	443	Shared Neighborhood Hits	144
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

FA76A_MOUSE
NC score	0.055394 (rank : 1975)	θ value	θ > 10 (rank : 1656)
Query Neighborhood Hits	1371	Target Neighborhood Hits	152	Shared Neighborhood Hits	100
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

SNUT1_MOUSE
NC score	0.055385 (rank : 1976)	θ value	θ > 10 (rank : 2166)
Query Neighborhood Hits	1371	Target Neighborhood Hits	159	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z315, Q8K155, Q9R1I9, Q9R270	Gene names	Sart1, Haf
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 1 (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (mSART-1) (Hypoxia- associated factor).

SEC63_MOUSE
NC score	0.055372 (rank : 1977)	θ value	θ > 10 (rank : 2124)
Query Neighborhood Hits	1371	Target Neighborhood Hits	601	Shared Neighborhood Hits	169
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

M3K12_MOUSE
NC score	0.055289 (rank : 1978)	θ value	θ > 10 (rank : 1893)
Query Neighborhood Hits	1371	Target Neighborhood Hits	957	Shared Neighborhood Hits	117
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

IRAK1_MOUSE
NC score	0.055288 (rank : 1979)	θ value	θ > 10 (rank : 1750)
Query Neighborhood Hits	1371	Target Neighborhood Hits	784	Shared Neighborhood Hits	92
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

HNRCL_HUMAN
NC score	0.055207 (rank : 1980)	θ value	θ > 10 (rank : 1722)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	100
SwissProt Accessions	O60812	Gene names	HNRPCL1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP core protein C-like 1).

DFFA_MOUSE
NC score	0.055116 (rank : 1981)	θ value	θ > 10 (rank : 1582)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	O54786, O54787	Gene names	Dffa, Icad
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

KPCT_HUMAN
NC score	0.055110 (rank : 1982)	θ value	θ > 10 (rank : 1841)
Query Neighborhood Hits	1371	Target Neighborhood Hits	897	Shared Neighborhood Hits	111
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

M3K13_HUMAN
NC score	0.055078 (rank : 1983)	θ value	θ > 10 (rank : 1894)
Query Neighborhood Hits	1371	Target Neighborhood Hits	911	Shared Neighborhood Hits	107
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

DDR2_HUMAN
NC score	0.055062 (rank : 1984)	θ value	θ > 10 (rank : 1575)
Query Neighborhood Hits	1371	Target Neighborhood Hits	818	Shared Neighborhood Hits	97
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

M3K12_HUMAN
NC score	0.055061 (rank : 1985)	θ value	θ > 10 (rank : 1892)
Query Neighborhood Hits	1371	Target Neighborhood Hits	940	Shared Neighborhood Hits	112
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

3BP1_HUMAN
NC score	0.055035 (rank : 1986)	θ value	θ > 10 (rank : 1372)
Query Neighborhood Hits	1371	Target Neighborhood Hits	376	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

KPCT_MOUSE
NC score	0.055017 (rank : 1987)	θ value	θ > 10 (rank : 1842)
Query Neighborhood Hits	1371	Target Neighborhood Hits	895	Shared Neighborhood Hits	111
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

K1967_MOUSE
NC score	0.054988 (rank : 1988)	θ value	θ > 10 (rank : 1772)
Query Neighborhood Hits	1371	Target Neighborhood Hits	136	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

DAPK3_HUMAN
NC score	0.054962 (rank : 1989)	θ value	0.0431538 (rank : 710)
Query Neighborhood Hits	1371	Target Neighborhood Hits	945	Shared Neighborhood Hits	187
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

KPCD_MOUSE
NC score	0.054885 (rank : 1990)	θ value	θ > 10 (rank : 1836)
Query Neighborhood Hits	1371	Target Neighborhood Hits	888	Shared Neighborhood Hits	112
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MOS_MOUSE
NC score	0.054850 (rank : 1991)	θ value	θ > 10 (rank : 1921)
Query Neighborhood Hits	1371	Target Neighborhood Hits	833	Shared Neighborhood Hits	96
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

RFC1_HUMAN
NC score	0.054709 (rank : 1992)	θ value	1.38821 (rank : 1065)
Query Neighborhood Hits	1371	Target Neighborhood Hits	352	Shared Neighborhood Hits	118
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

ERBB3_MOUSE
NC score	0.054692 (rank : 1993)	θ value	θ > 10 (rank : 1645)
Query Neighborhood Hits	1371	Target Neighborhood Hits	898	Shared Neighborhood Hits	93
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

NRBF2_MOUSE
NC score	0.054675 (rank : 1994)	θ value	θ > 10 (rank : 1982)
Query Neighborhood Hits	1371	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

ERBB2_HUMAN
NC score	0.054673 (rank : 1995)	θ value	θ > 10 (rank : 1642)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1073	Shared Neighborhood Hits	114
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

E2AK4_HUMAN
NC score	0.054600 (rank : 1996)	θ value	θ > 10 (rank : 1608)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1012	Shared Neighborhood Hits	193
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

ABCF1_MOUSE
NC score	0.054529 (rank : 1997)	θ value	θ > 10 (rank : 1379)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	113
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

NRK_HUMAN
NC score	0.054489 (rank : 1998)	θ value	θ > 10 (rank : 1983)
Query Neighborhood Hits	1371	Target Neighborhood Hits	931	Shared Neighborhood Hits	131
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

TCAL5_HUMAN
NC score	0.054489 (rank : 1999)	θ value	θ > 10 (rank : 2260)
Query Neighborhood Hits	1371	Target Neighborhood Hits	806	Shared Neighborhood Hits	147
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

KLC2_MOUSE
NC score	0.054429 (rank : 2000)	θ value	θ > 10 (rank : 1832)
Query Neighborhood Hits	1371	Target Neighborhood Hits	244	Shared Neighborhood Hits	156
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

ERBB2_MOUSE
NC score	0.054421 (rank : 2001)	θ value	θ > 10 (rank : 1643)
Query Neighborhood Hits	1371	Target Neighborhood Hits	918	Shared Neighborhood Hits	101
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

LEO1_HUMAN
NC score	0.054419 (rank : 2002)	θ value	θ > 10 (rank : 1876)
Query Neighborhood Hits	1371	Target Neighborhood Hits	958	Shared Neighborhood Hits	203
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RLP24_MOUSE
NC score	0.054419 (rank : 2003)	θ value	θ > 10 (rank : 2093)
Query Neighborhood Hits	1371	Target Neighborhood Hits	65	Shared Neighborhood Hits	52
SwissProt Accessions	Q99L28	Gene names
Domain Architecture	No domain graphic available
Description	Probable ribosome biogenesis protein RLP24.

BST2_MOUSE
NC score	0.054401 (rank : 2004)	θ value	θ > 10 (rank : 1466)
Query Neighborhood Hits	1371	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R2Q8, Q8CEY7	Gene names	Bst2
Domain Architecture	No domain graphic available
Description	Bone marrow stromal antigen 2 precursor (BST-2) (CD317 antigen) (HM1.24 antigen).

KPCD_HUMAN
NC score	0.054397 (rank : 2005)	θ value	θ > 10 (rank : 1835)
Query Neighborhood Hits	1371	Target Neighborhood Hits	900	Shared Neighborhood Hits	114
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MET_MOUSE
NC score	0.054382 (rank : 2006)	θ value	θ > 10 (rank : 1908)
Query Neighborhood Hits	1371	Target Neighborhood Hits	844	Shared Neighborhood Hits	94
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

RIPK2_HUMAN
NC score	0.054356 (rank : 2007)	θ value	θ > 10 (rank : 2089)
Query Neighborhood Hits	1371	Target Neighborhood Hits	774	Shared Neighborhood Hits	91
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

EPHAA_HUMAN
NC score	0.054314 (rank : 2008)	θ value	θ > 10 (rank : 1633)
Query Neighborhood Hits	1371	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

KI67_HUMAN
NC score	0.054307 (rank : 2009)	θ value	θ > 10 (rank : 1809)
Query Neighborhood Hits	1371	Target Neighborhood Hits	581	Shared Neighborhood Hits	153
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MOS_HUMAN
NC score	0.054288 (rank : 2010)	θ value	θ > 10 (rank : 1920)
Query Neighborhood Hits	1371	Target Neighborhood Hits	829	Shared Neighborhood Hits	94
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

ERBB3_HUMAN
NC score	0.054278 (rank : 2011)	θ value	θ > 10 (rank : 1644)
Query Neighborhood Hits	1371	Target Neighborhood Hits	918	Shared Neighborhood Hits	93
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

IWS1_MOUSE
NC score	0.054251 (rank : 2012)	θ value	θ > 10 (rank : 1755)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1258	Shared Neighborhood Hits	216
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RIPK4_HUMAN
NC score	0.054223 (rank : 2013)	θ value	θ > 10 (rank : 2091)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1094	Shared Neighborhood Hits	127
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

TBK1_HUMAN
NC score	0.054127 (rank : 2014)	θ value	θ > 10 (rank : 2258)
Query Neighborhood Hits	1371	Target Neighborhood Hits	861	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UHD2, Q8IYV3, Q9NUJ5	Gene names	TBK1, NAK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K) (NF-kappa-B-activating kinase).

EPHA1_MOUSE
NC score	0.054120 (rank : 2015)	θ value	θ > 10 (rank : 1618)
Query Neighborhood Hits	1371	Target Neighborhood Hits	958	Shared Neighborhood Hits	101
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

HSF2_HUMAN
NC score	0.054054 (rank : 2016)	θ value	θ > 10 (rank : 1727)
Query Neighborhood Hits	1371	Target Neighborhood Hits	149	Shared Neighborhood Hits	100
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

MLKL_HUMAN
NC score	0.053989 (rank : 2017)	θ value	θ > 10 (rank : 1912)
Query Neighborhood Hits	1371	Target Neighborhood Hits	600	Shared Neighborhood Hits	94
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

RIPK5_MOUSE
NC score	0.053984 (rank : 2018)	θ value	θ > 10 (rank : 2092)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	118
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

MORC1_HUMAN
NC score	0.053968 (rank : 2019)	θ value	6.88961 (rank : 1306)
Query Neighborhood Hits	1371	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q86VD1, Q7L8E2, Q9NSG7, Q9Y6D4	Gene names	MORC1, MORC
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 1.

TOP1_HUMAN
NC score	0.053962 (rank : 2020)	θ value	θ > 10 (rank : 2286)
Query Neighborhood Hits	1371	Target Neighborhood Hits	207	Shared Neighborhood Hits	107
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

JAK3_HUMAN
NC score	0.053944 (rank : 2021)	θ value	θ > 10 (rank : 1760)
Query Neighborhood Hits	1371	Target Neighborhood Hits	827	Shared Neighborhood Hits	95
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

ABCF1_HUMAN
NC score	0.053934 (rank : 2022)	θ value	θ > 10 (rank : 1378)
Query Neighborhood Hits	1371	Target Neighborhood Hits	343	Shared Neighborhood Hits	124
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

HSP74_MOUSE
NC score	0.053926 (rank : 2023)	θ value	θ > 10 (rank : 1731)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	143
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

DDR2_MOUSE
NC score	0.053914 (rank : 2024)	θ value	θ > 10 (rank : 1576)
Query Neighborhood Hits	1371	Target Neighborhood Hits	813	Shared Neighborhood Hits	95
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

LSD1_MOUSE
NC score	0.053780 (rank : 2025)	θ value	6.88961 (rank : 1303)
Query Neighborhood Hits	1371	Target Neighborhood Hits	224	Shared Neighborhood Hits	116
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

NEK2_HUMAN
NC score	0.053739 (rank : 2026)	θ value	θ > 10 (rank : 1969)
Query Neighborhood Hits	1371	Target Neighborhood Hits	908	Shared Neighborhood Hits	166
SwissProt Accessions	P51955, Q53FD6, Q5VXZ1, Q6NZX8, Q7Z634, Q86XH2, Q96QN9	Gene names	NEK2, NLK1
Domain Architecture
Description	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21).

RIPK2_MOUSE
NC score	0.053733 (rank : 2027)	θ value	θ > 10 (rank : 2090)
Query Neighborhood Hits	1371	Target Neighborhood Hits	776	Shared Neighborhood Hits	91
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

APOA5_MOUSE
NC score	0.053729 (rank : 2028)	θ value	θ > 10 (rank : 1420)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C7G5, Q91X90, Q99P64	Gene names	Apoa5, Rap3
Domain Architecture	No domain graphic available
Description	Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration-associated protein 3).

EGFR_HUMAN
NC score	0.053729 (rank : 2029)	θ value	θ > 10 (rank : 1611)
Query Neighborhood Hits	1371	Target Neighborhood Hits	939	Shared Neighborhood Hits	101
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EPHA1_HUMAN
NC score	0.053691 (rank : 2030)	θ value	θ > 10 (rank : 1617)
Query Neighborhood Hits	1371	Target Neighborhood Hits	997	Shared Neighborhood Hits	104
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

RON_HUMAN
NC score	0.053651 (rank : 2031)	θ value	θ > 10 (rank : 2098)
Query Neighborhood Hits	1371	Target Neighborhood Hits	842	Shared Neighborhood Hits	94
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

EGFR_MOUSE
NC score	0.053611 (rank : 2032)	θ value	θ > 10 (rank : 1612)
Query Neighborhood Hits	1371	Target Neighborhood Hits	927	Shared Neighborhood Hits	98
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

KPCL_MOUSE
NC score	0.053605 (rank : 2033)	θ value	θ > 10 (rank : 1840)
Query Neighborhood Hits	1371	Target Neighborhood Hits	891	Shared Neighborhood Hits	125
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

CD016_HUMAN
NC score	0.053595 (rank : 2034)	θ value	θ > 10 (rank : 1494)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	52
SwissProt Accessions	Q63HQ0, Q96GG6, Q9H0V0, Q9P1L4	Gene names	C4orf16
Domain Architecture	No domain graphic available
Description	Protein C4orf16.

SRPK2_MOUSE
NC score	0.053591 (rank : 2035)	θ value	θ > 10 (rank : 2187)
Query Neighborhood Hits	1371	Target Neighborhood Hits	765	Shared Neighborhood Hits	188
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

MET_HUMAN
NC score	0.053560 (rank : 2036)	θ value	θ > 10 (rank : 1907)
Query Neighborhood Hits	1371	Target Neighborhood Hits	831	Shared Neighborhood Hits	95
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

RON_MOUSE
NC score	0.053486 (rank : 2037)	θ value	θ > 10 (rank : 2099)
Query Neighborhood Hits	1371	Target Neighborhood Hits	836	Shared Neighborhood Hits	95
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

PTN23_HUMAN
NC score	0.053402 (rank : 2038)	θ value	θ > 10 (rank : 2049)
Query Neighborhood Hits	1371	Target Neighborhood Hits	646	Shared Neighborhood Hits	195
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

IRAK4_HUMAN
NC score	0.053380 (rank : 2039)	θ value	θ > 10 (rank : 1752)
Query Neighborhood Hits	1371	Target Neighborhood Hits	816	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

RIPK1_MOUSE
NC score	0.053347 (rank : 2040)	θ value	θ > 10 (rank : 2088)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	98
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

NTRK1_HUMAN
NC score	0.053337 (rank : 2041)	θ value	θ > 10 (rank : 1988)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1023	Shared Neighborhood Hits	96
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

EPHA5_MOUSE
NC score	0.053326 (rank : 2042)	θ value	θ > 10 (rank : 1626)
Query Neighborhood Hits	1371	Target Neighborhood Hits	950	Shared Neighborhood Hits	100
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

MYPT1_MOUSE
NC score	0.053295 (rank : 2043)	θ value	θ > 10 (rank : 1951)
Query Neighborhood Hits	1371	Target Neighborhood Hits	539	Shared Neighborhood Hits	158
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

BCAR3_HUMAN
NC score	0.053279 (rank : 2044)	θ value	θ > 10 (rank : 1441)
Query Neighborhood Hits	1371	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

STK24_MOUSE
NC score	0.053241 (rank : 2045)	θ value	θ > 10 (rank : 2196)
Query Neighborhood Hits	1371	Target Neighborhood Hits	856	Shared Neighborhood Hits	98
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

MYRIP_HUMAN
NC score	0.053238 (rank : 2046)	θ value	θ > 10 (rank : 1953)
Query Neighborhood Hits	1371	Target Neighborhood Hits	269	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

IRAK4_MOUSE
NC score	0.053215 (rank : 2047)	θ value	θ > 10 (rank : 1753)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	96
SwissProt Accessions	Q8R4K2, Q80WW1	Gene names	Irak4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4).

PTN6_MOUSE
NC score	0.053204 (rank : 2048)	θ value	θ > 10 (rank : 2052)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	74
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

ZFYV1_HUMAN
NC score	0.053172 (rank : 2049)	θ value	θ > 10 (rank : 2352)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

CLSPN_MOUSE
NC score	0.053164 (rank : 2050)	θ value	θ > 10 (rank : 1534)
Query Neighborhood Hits	1371	Target Neighborhood Hits	292	Shared Neighborhood Hits	113
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

SFR16_MOUSE
NC score	0.053151 (rank : 2051)	θ value	θ > 10 (rank : 2132)
Query Neighborhood Hits	1371	Target Neighborhood Hits	177	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CFC7, Q8CFC8, Q9Z2N3	Gene names	Sfrs16, Clasp, Swap2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2) (Clk4-associating SR-related protein).

PKN2_MOUSE
NC score	0.053134 (rank : 2052)	θ value	θ > 10 (rank : 2032)
Query Neighborhood Hits	1371	Target Neighborhood Hits	899	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

RIPK5_HUMAN
NC score	0.053129 (rank : 2053)	θ value	8.99809 (rank : 1358)
Query Neighborhood Hits	1371	Target Neighborhood Hits	864	Shared Neighborhood Hits	109
SwissProt Accessions	Q6XUX3, O75060, Q5RKT0, Q6IN87, Q6P997, Q86Y03, Q9P1S5	Gene names	RIPK5, KIAA0472, RIP5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase).

PKN2_HUMAN
NC score	0.053104 (rank : 2054)	θ value	θ > 10 (rank : 2031)
Query Neighborhood Hits	1371	Target Neighborhood Hits	892	Shared Neighborhood Hits	133
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

VCXC_HUMAN
NC score	0.053081 (rank : 2055)	θ value	θ > 10 (rank : 2321)
Query Neighborhood Hits	1371	Target Neighborhood Hits	139	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

IGF1R_MOUSE
NC score	0.053031 (rank : 2056)	θ value	θ > 10 (rank : 1737)
Query Neighborhood Hits	1371	Target Neighborhood Hits	973	Shared Neighborhood Hits	94
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KSR2_HUMAN
NC score	0.053025 (rank : 2057)	θ value	θ > 10 (rank : 1853)
Query Neighborhood Hits	1371	Target Neighborhood Hits	920	Shared Neighborhood Hits	108
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

TYK2_HUMAN
NC score	0.053000 (rank : 2058)	θ value	θ > 10 (rank : 2305)
Query Neighborhood Hits	1371	Target Neighborhood Hits	841	Shared Neighborhood Hits	92
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

PKN3_MOUSE
NC score	0.052956 (rank : 2059)	θ value	θ > 10 (rank : 2033)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	153
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

IGF1R_HUMAN
NC score	0.052949 (rank : 2060)	θ value	θ > 10 (rank : 1736)
Query Neighborhood Hits	1371	Target Neighborhood Hits	977	Shared Neighborhood Hits	95
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

DMP1_MOUSE
NC score	0.052942 (rank : 2061)	θ value	θ > 10 (rank : 1591)
Query Neighborhood Hits	1371	Target Neighborhood Hits	498	Shared Neighborhood Hits	105
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

HDAC9_HUMAN
NC score	0.052856 (rank : 2062)	θ value	θ > 10 (rank : 1717)
Query Neighborhood Hits	1371	Target Neighborhood Hits	201	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

KPCL_HUMAN
NC score	0.052803 (rank : 2063)	θ value	θ > 10 (rank : 1839)
Query Neighborhood Hits	1371	Target Neighborhood Hits	887	Shared Neighborhood Hits	121
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

STK25_MOUSE
NC score	0.052802 (rank : 2064)	θ value	θ > 10 (rank : 2198)
Query Neighborhood Hits	1371	Target Neighborhood Hits	851	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

CTNL1_HUMAN
NC score	0.052767 (rank : 2065)	θ value	θ > 10 (rank : 1558)
Query Neighborhood Hits	1371	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UBT7, O76084, Q53FQ2, Q5JTQ7, Q5JTQ8, Q9Y401	Gene names	CTNNAL1
Domain Architecture	No domain graphic available
Description	Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) (ACRP).

TANK_MOUSE
NC score	0.052752 (rank : 2066)	θ value	θ > 10 (rank : 2252)
Query Neighborhood Hits	1371	Target Neighborhood Hits	80	Shared Neighborhood Hits	62
SwissProt Accessions	P70347, Q61178	Gene names	Tank, Itraf
Domain Architecture
Description	TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF).

HSF2_MOUSE
NC score	0.052746 (rank : 2067)	θ value	θ > 10 (rank : 1728)
Query Neighborhood Hits	1371	Target Neighborhood Hits	153	Shared Neighborhood Hits	103
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

DDX11_HUMAN
NC score	0.052739 (rank : 2068)	θ value	θ > 10 (rank : 1577)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	93
SwissProt Accessions	Q96FC9, Q13333, Q86VQ4, Q86W62, Q92498, Q92770, Q92998, Q92999	Gene names	DDX11, CHL1, CHLR1, KRG2
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11) (CHL1 homolog) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2).

NRK_MOUSE
NC score	0.052718 (rank : 2069)	θ value	θ > 10 (rank : 1984)
Query Neighborhood Hits	1371	Target Neighborhood Hits	899	Shared Neighborhood Hits	111
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

INSRR_MOUSE
NC score	0.052717 (rank : 2070)	θ value	θ > 10 (rank : 1744)
Query Neighborhood Hits	1371	Target Neighborhood Hits	961	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

FAM9A_HUMAN
NC score	0.052700 (rank : 2071)	θ value	θ > 10 (rank : 1662)
Query Neighborhood Hits	1371	Target Neighborhood Hits	138	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

INSRR_HUMAN
NC score	0.052678 (rank : 2072)	θ value	θ > 10 (rank : 1743)
Query Neighborhood Hits	1371	Target Neighborhood Hits	950	Shared Neighborhood Hits	93
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

EPHA6_HUMAN
NC score	0.052598 (rank : 2073)	θ value	θ > 10 (rank : 1627)
Query Neighborhood Hits	1371	Target Neighborhood Hits	959	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

UFO_MOUSE
NC score	0.052594 (rank : 2074)	θ value	θ > 10 (rank : 2310)
Query Neighborhood Hits	1371	Target Neighborhood Hits	988	Shared Neighborhood Hits	94
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

STK25_HUMAN
NC score	0.052589 (rank : 2075)	θ value	θ > 10 (rank : 2197)
Query Neighborhood Hits	1371	Target Neighborhood Hits	853	Shared Neighborhood Hits	94
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

GABP2_HUMAN
NC score	0.052562 (rank : 2076)	θ value	0.279714 (rank : 879)
Query Neighborhood Hits	1371	Target Neighborhood Hits	454	Shared Neighborhood Hits	144
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

EPHA6_MOUSE
NC score	0.052556 (rank : 2077)	θ value	θ > 10 (rank : 1628)
Query Neighborhood Hits	1371	Target Neighborhood Hits	946	Shared Neighborhood Hits	102
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

STK24_HUMAN
NC score	0.052542 (rank : 2078)	θ value	θ > 10 (rank : 2195)
Query Neighborhood Hits	1371	Target Neighborhood Hits	853	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

NEK11_MOUSE
NC score	0.052536 (rank : 2079)	θ value	θ > 10 (rank : 1966)
Query Neighborhood Hits	1371	Target Neighborhood Hits	875	Shared Neighborhood Hits	113
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

UFO_HUMAN
NC score	0.052514 (rank : 2080)	θ value	θ > 10 (rank : 2309)
Query Neighborhood Hits	1371	Target Neighborhood Hits	981	Shared Neighborhood Hits	95
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

IRAK1_HUMAN
NC score	0.052510 (rank : 2081)	θ value	θ > 10 (rank : 1749)
Query Neighborhood Hits	1371	Target Neighborhood Hits	820	Shared Neighborhood Hits	97
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

PTN6_HUMAN
NC score	0.052504 (rank : 2082)	θ value	θ > 10 (rank : 2051)
Query Neighborhood Hits	1371	Target Neighborhood Hits	234	Shared Neighborhood Hits	79
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

TYK2_MOUSE
NC score	0.052443 (rank : 2083)	θ value	θ > 10 (rank : 2306)
Query Neighborhood Hits	1371	Target Neighborhood Hits	850	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

RIPK1_HUMAN
NC score	0.052375 (rank : 2084)	θ value	θ > 10 (rank : 2087)
Query Neighborhood Hits	1371	Target Neighborhood Hits	891	Shared Neighborhood Hits	99
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

SF3B2_HUMAN
NC score	0.052348 (rank : 2085)	θ value	θ > 10 (rank : 2128)
Query Neighborhood Hits	1371	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

SMRC1_MOUSE
NC score	0.052333 (rank : 2086)	θ value	θ > 10 (rank : 2160)
Query Neighborhood Hits	1371	Target Neighborhood Hits	459	Shared Neighborhood Hits	155
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

GMIP_MOUSE
NC score	0.052332 (rank : 2087)	θ value	θ > 10 (rank : 1699)
Query Neighborhood Hits	1371	Target Neighborhood Hits	202	Shared Neighborhood Hits	87
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

MST4_HUMAN
NC score	0.052316 (rank : 2088)	θ value	θ > 10 (rank : 1928)
Query Neighborhood Hits	1371	Target Neighborhood Hits	852	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

INSR_MOUSE
NC score	0.052312 (rank : 2089)	θ value	θ > 10 (rank : 1746)
Query Neighborhood Hits	1371	Target Neighborhood Hits	968	Shared Neighborhood Hits	96
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

STK39_MOUSE
NC score	0.052300 (rank : 2090)	θ value	θ > 10 (rank : 2202)
Query Neighborhood Hits	1371	Target Neighborhood Hits	915	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

MST4_MOUSE
NC score	0.052295 (rank : 2091)	θ value	θ > 10 (rank : 1929)
Query Neighborhood Hits	1371	Target Neighborhood Hits	860	Shared Neighborhood Hits	95
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

JAK3_MOUSE
NC score	0.052285 (rank : 2092)	θ value	θ > 10 (rank : 1761)
Query Neighborhood Hits	1371	Target Neighborhood Hits	821	Shared Neighborhood Hits	94
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

BLNK_HUMAN
NC score	0.052255 (rank : 2093)	θ value	θ > 10 (rank : 1453)
Query Neighborhood Hits	1371	Target Neighborhood Hits	228	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

CMGA_HUMAN
NC score	0.052238 (rank : 2094)	θ value	θ > 10 (rank : 1537)
Query Neighborhood Hits	1371	Target Neighborhood Hits	238	Shared Neighborhood Hits	86
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

PKN1_MOUSE
NC score	0.052204 (rank : 2095)	θ value	θ > 10 (rank : 2030)
Query Neighborhood Hits	1371	Target Neighborhood Hits	888	Shared Neighborhood Hits	123
SwissProt Accessions	P70268, Q7TST2	Gene names	Pkn1, Pkn, Prk1, Prkcl1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N).

CLC4M_HUMAN
NC score	0.052168 (rank : 2096)	θ value	θ > 10 (rank : 1531)
Query Neighborhood Hits	1371	Target Neighborhood Hits	291	Shared Neighborhood Hits	120
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

MYST4_HUMAN
NC score	0.052118 (rank : 2097)	θ value	θ > 10 (rank : 1955)
Query Neighborhood Hits	1371	Target Neighborhood Hits	671	Shared Neighborhood Hits	196
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

LSD1_HUMAN
NC score	0.052093 (rank : 2098)	θ value	6.88961 (rank : 1302)
Query Neighborhood Hits	1371	Target Neighborhood Hits	455	Shared Neighborhood Hits	128
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

EPHA8_MOUSE
NC score	0.052058 (rank : 2099)	θ value	θ > 10 (rank : 1632)
Query Neighborhood Hits	1371	Target Neighborhood Hits	969	Shared Neighborhood Hits	100
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

STK39_HUMAN
NC score	0.052052 (rank : 2100)	θ value	θ > 10 (rank : 2201)
Query Neighborhood Hits	1371	Target Neighborhood Hits	882	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

EPHB1_HUMAN
NC score	0.052045 (rank : 2101)	θ value	θ > 10 (rank : 1634)
Query Neighborhood Hits	1371	Target Neighborhood Hits	988	Shared Neighborhood Hits	105
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

STX7_MOUSE
NC score	0.051988 (rank : 2102)	θ value	θ > 10 (rank : 2216)
Query Neighborhood Hits	1371	Target Neighborhood Hits	131	Shared Neighborhood Hits	82
SwissProt Accessions	O70439	Gene names	Stx7, Syn7
Domain Architecture
Description	Syntaxin-7.

LATS1_HUMAN
NC score	0.051979 (rank : 2103)	θ value	0.365318 (rank : 912)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1057	Shared Neighborhood Hits	159
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

INSR_HUMAN
NC score	0.051974 (rank : 2104)	θ value	θ > 10 (rank : 1745)
Query Neighborhood Hits	1371	Target Neighborhood Hits	963	Shared Neighborhood Hits	94
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

MLKL_MOUSE
NC score	0.051963 (rank : 2105)	θ value	θ > 10 (rank : 1913)
Query Neighborhood Hits	1371	Target Neighborhood Hits	707	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

RET_HUMAN
NC score	0.051936 (rank : 2106)	θ value	θ > 10 (rank : 2071)
Query Neighborhood Hits	1371	Target Neighborhood Hits	873	Shared Neighborhood Hits	96
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

ZMAT2_HUMAN
NC score	0.051900 (rank : 2107)	θ value	θ > 10 (rank : 2355)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	Q96NC0	Gene names	ZMAT2
Domain Architecture	No domain graphic available
Description	Zinc finger matrin type 2.

ZMAT2_MOUSE
NC score	0.051900 (rank : 2108)	θ value	θ > 10 (rank : 2356)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CPW7, Q5EBK0	Gene names	Zmat2
Domain Architecture	No domain graphic available
Description	Zinc finger matrin type 2.

SRRM2_MOUSE
NC score	0.051886 (rank : 2109)	θ value	θ > 10 (rank : 2190)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1470	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

FLT3_HUMAN
NC score	0.051815 (rank : 2110)	θ value	θ > 10 (rank : 1674)
Query Neighborhood Hits	1371	Target Neighborhood Hits	843	Shared Neighborhood Hits	96
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

SMCA2_HUMAN
NC score	0.051789 (rank : 2111)	θ value	θ > 10 (rank : 2157)
Query Neighborhood Hits	1371	Target Neighborhood Hits	503	Shared Neighborhood Hits	175
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

TCOF_MOUSE
NC score	0.051777 (rank : 2112)	θ value	θ > 10 (rank : 2261)
Query Neighborhood Hits	1371	Target Neighborhood Hits	471	Shared Neighborhood Hits	96
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ANK2_HUMAN
NC score	0.051768 (rank : 2113)	θ value	θ > 10 (rank : 1407)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1615	Shared Neighborhood Hits	281
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MUT_MOUSE
NC score	0.051732 (rank : 2114)	θ value	θ > 10 (rank : 1933)
Query Neighborhood Hits	1371	Target Neighborhood Hits	52	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R015, Q3TCP2, Q8CAC9	Gene names	Muted, Mu
Domain Architecture	No domain graphic available
Description	Muted protein.

EPHA8_HUMAN
NC score	0.051672 (rank : 2115)	θ value	θ > 10 (rank : 1631)
Query Neighborhood Hits	1371	Target Neighborhood Hits	956	Shared Neighborhood Hits	99
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

FYB_HUMAN
NC score	0.051657 (rank : 2116)	θ value	θ > 10 (rank : 1681)
Query Neighborhood Hits	1371	Target Neighborhood Hits	379	Shared Neighborhood Hits	101
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

EPHA2_MOUSE
NC score	0.051581 (rank : 2117)	θ value	θ > 10 (rank : 1620)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1020	Shared Neighborhood Hits	107
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHB3_HUMAN
NC score	0.051552 (rank : 2118)	θ value	θ > 10 (rank : 1637)
Query Neighborhood Hits	1371	Target Neighborhood Hits	996	Shared Neighborhood Hits	111
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB6_MOUSE
NC score	0.051540 (rank : 2119)	θ value	θ > 10 (rank : 1641)
Query Neighborhood Hits	1371	Target Neighborhood Hits	906	Shared Neighborhood Hits	97
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FLT3_MOUSE
NC score	0.051504 (rank : 2120)	θ value	θ > 10 (rank : 1675)
Query Neighborhood Hits	1371	Target Neighborhood Hits	847	Shared Neighborhood Hits	92
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

JAK2_MOUSE
NC score	0.051504 (rank : 2121)	θ value	θ > 10 (rank : 1759)
Query Neighborhood Hits	1371	Target Neighborhood Hits	839	Shared Neighborhood Hits	99
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

EPHB2_HUMAN
NC score	0.051483 (rank : 2122)	θ value	θ > 10 (rank : 1635)
Query Neighborhood Hits	1371	Target Neighborhood Hits	983	Shared Neighborhood Hits	102
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHA2_HUMAN
NC score	0.051444 (rank : 2123)	θ value	θ > 10 (rank : 1619)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1021	Shared Neighborhood Hits	109
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

E2AK4_MOUSE
NC score	0.051444 (rank : 2124)	θ value	θ > 10 (rank : 1609)
Query Neighborhood Hits	1371	Target Neighborhood Hits	984	Shared Neighborhood Hits	162
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

DOCK2_MOUSE
NC score	0.051431 (rank : 2125)	θ value	0.813845 (rank : 979)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

ANGP4_HUMAN
NC score	0.051430 (rank : 2126)	θ value	θ > 10 (rank : 1406)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

EPHB2_MOUSE
NC score	0.051428 (rank : 2127)	θ value	θ > 10 (rank : 1636)
Query Neighborhood Hits	1371	Target Neighborhood Hits	982	Shared Neighborhood Hits	102
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHA4_HUMAN
NC score	0.051421 (rank : 2128)	θ value	θ > 10 (rank : 1623)
Query Neighborhood Hits	1371	Target Neighborhood Hits	975	Shared Neighborhood Hits	104
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
NC score	0.051412 (rank : 2129)	θ value	θ > 10 (rank : 1624)
Query Neighborhood Hits	1371	Target Neighborhood Hits	982	Shared Neighborhood Hits	105
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

RNF17_MOUSE
NC score	0.051382 (rank : 2130)	θ value	θ > 10 (rank : 2095)
Query Neighborhood Hits	1371	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

EPHA5_HUMAN
NC score	0.051327 (rank : 2131)	θ value	θ > 10 (rank : 1625)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	104
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHB4_HUMAN
NC score	0.051308 (rank : 2132)	θ value	θ > 10 (rank : 1639)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1056	Shared Neighborhood Hits	103
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

RYK_HUMAN
NC score	0.051300 (rank : 2133)	θ value	θ > 10 (rank : 2107)
Query Neighborhood Hits	1371	Target Neighborhood Hits	701	Shared Neighborhood Hits	77
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

EPHB3_MOUSE
NC score	0.051279 (rank : 2134)	θ value	θ > 10 (rank : 1638)
Query Neighborhood Hits	1371	Target Neighborhood Hits	996	Shared Neighborhood Hits	110
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

RET_MOUSE
NC score	0.051241 (rank : 2135)	θ value	θ > 10 (rank : 2072)
Query Neighborhood Hits	1371	Target Neighborhood Hits	884	Shared Neighborhood Hits	95
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

WNK3_HUMAN
NC score	0.051236 (rank : 2136)	θ value	θ > 10 (rank : 2329)
Query Neighborhood Hits	1371	Target Neighborhood Hits	948	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

OXSR1_MOUSE
NC score	0.051228 (rank : 2137)	θ value	θ > 10 (rank : 2002)
Query Neighborhood Hits	1371	Target Neighborhood Hits	865	Shared Neighborhood Hits	97
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

JAK2_HUMAN
NC score	0.051188 (rank : 2138)	θ value	θ > 10 (rank : 1758)
Query Neighborhood Hits	1371	Target Neighborhood Hits	847	Shared Neighborhood Hits	99
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

STX5_MOUSE
NC score	0.051173 (rank : 2139)	θ value	θ > 10 (rank : 2215)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K1E0, Q3TM79, Q99J28, Q9JKP2	Gene names	Stx5, Stx5a
Domain Architecture
Description	Syntaxin-5.

PTN23_MOUSE
NC score	0.051140 (rank : 2140)	θ value	θ > 10 (rank : 2050)
Query Neighborhood Hits	1371	Target Neighborhood Hits	726	Shared Neighborhood Hits	210
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

BAZ2A_MOUSE
NC score	0.051132 (rank : 2141)	θ value	θ > 10 (rank : 1439)
Query Neighborhood Hits	1371	Target Neighborhood Hits	744	Shared Neighborhood Hits	183
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

RYK_MOUSE
NC score	0.051088 (rank : 2142)	θ value	θ > 10 (rank : 2108)
Query Neighborhood Hits	1371	Target Neighborhood Hits	715	Shared Neighborhood Hits	79
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

JAK1_HUMAN
NC score	0.051057 (rank : 2143)	θ value	θ > 10 (rank : 1756)
Query Neighborhood Hits	1371	Target Neighborhood Hits	858	Shared Neighborhood Hits	99
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

PLSL_HUMAN
NC score	0.051052 (rank : 2144)	θ value	6.88961 (rank : 1310)
Query Neighborhood Hits	1371	Target Neighborhood Hits	168	Shared Neighborhood Hits	61
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

EPHA3_HUMAN
NC score	0.051046 (rank : 2145)	θ value	θ > 10 (rank : 1621)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1005	Shared Neighborhood Hits	99
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHB4_MOUSE
NC score	0.051029 (rank : 2146)	θ value	θ > 10 (rank : 1640)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1013	Shared Neighborhood Hits	104
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHA7_MOUSE
NC score	0.050973 (rank : 2147)	θ value	θ > 10 (rank : 1630)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1025	Shared Neighborhood Hits	105
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

APOA5_HUMAN
NC score	0.050940 (rank : 2148)	θ value	θ > 10 (rank : 1419)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	78
SwissProt Accessions	Q6Q788, Q6UWK9, Q9UBJ3	Gene names	APOA5, RAP3
Domain Architecture	No domain graphic available
Description	Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration-associated protein 3).

KGUA_MOUSE
NC score	0.050930 (rank : 2149)	θ value	θ > 10 (rank : 1805)
Query Neighborhood Hits	1371	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

WNK2_HUMAN
NC score	0.050887 (rank : 2150)	θ value	θ > 10 (rank : 2328)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1407	Shared Neighborhood Hits	165
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

IRAK2_HUMAN
NC score	0.050873 (rank : 2151)	θ value	θ > 10 (rank : 1751)
Query Neighborhood Hits	1371	Target Neighborhood Hits	714	Shared Neighborhood Hits	91
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

EPHA3_MOUSE
NC score	0.050834 (rank : 2152)	θ value	θ > 10 (rank : 1622)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1009	Shared Neighborhood Hits	100
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

ROR1_MOUSE
NC score	0.050802 (rank : 2153)	θ value	θ > 10 (rank : 2101)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1025	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

IF4G3_MOUSE
NC score	0.050799 (rank : 2154)	θ value	0.21417 (rank : 844)
Query Neighborhood Hits	1371	Target Neighborhood Hits	279	Shared Neighborhood Hits	99
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

OXSR1_HUMAN
NC score	0.050774 (rank : 2155)	θ value	θ > 10 (rank : 2001)
Query Neighborhood Hits	1371	Target Neighborhood Hits	874	Shared Neighborhood Hits	98
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

CSF1R_HUMAN
NC score	0.050746 (rank : 2156)	θ value	θ > 10 (rank : 1550)
Query Neighborhood Hits	1371	Target Neighborhood Hits	943	Shared Neighborhood Hits	93
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

NUPL1_HUMAN
NC score	0.050738 (rank : 2157)	θ value	θ > 10 (rank : 1994)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BVL2, O43160	Gene names	NUPL1, KIAA0410
Domain Architecture	No domain graphic available
Description	Nucleoporin p58/p45 (Nucleoporin-like 1).

ZFYV1_MOUSE
NC score	0.050736 (rank : 2158)	θ value	θ > 10 (rank : 2353)
Query Neighborhood Hits	1371	Target Neighborhood Hits	153	Shared Neighborhood Hits	30
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

EPHA7_HUMAN
NC score	0.050733 (rank : 2159)	θ value	θ > 10 (rank : 1629)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1053	Shared Neighborhood Hits	105
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

YSK4_HUMAN
NC score	0.050710 (rank : 2160)	θ value	θ > 10 (rank : 2340)
Query Neighborhood Hits	1371	Target Neighborhood Hits	921	Shared Neighborhood Hits	120
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

SOCS6_MOUSE
NC score	0.050677 (rank : 2161)	θ value	θ > 10 (rank : 2170)
Query Neighborhood Hits	1371	Target Neighborhood Hits	146	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

LIMK1_HUMAN
NC score	0.050627 (rank : 2162)	θ value	θ > 10 (rank : 1879)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1005	Shared Neighborhood Hits	115
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
NC score	0.050619 (rank : 2163)	θ value	θ > 10 (rank : 1880)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1008	Shared Neighborhood Hits	114
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

TOP1_MOUSE
NC score	0.050495 (rank : 2164)	θ value	θ > 10 (rank : 2287)
Query Neighborhood Hits	1371	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

BCAR3_MOUSE
NC score	0.050492 (rank : 2165)	θ value	θ > 10 (rank : 1442)
Query Neighborhood Hits	1371	Target Neighborhood Hits	127	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

JAK1_MOUSE
NC score	0.050458 (rank : 2166)	θ value	θ > 10 (rank : 1757)
Query Neighborhood Hits	1371	Target Neighborhood Hits	854	Shared Neighborhood Hits	96
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

SNW1_MOUSE
NC score	0.050395 (rank : 2167)	θ value	θ > 10 (rank : 2168)
Query Neighborhood Hits	1371	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

ROR1_HUMAN
NC score	0.050357 (rank : 2168)	θ value	θ > 10 (rank : 2100)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1018	Shared Neighborhood Hits	95
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

RHG05_MOUSE
NC score	0.050352 (rank : 2169)	θ value	θ > 10 (rank : 2076)
Query Neighborhood Hits	1371	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SNW1_HUMAN
NC score	0.050342 (rank : 2170)	θ value	θ > 10 (rank : 2167)
Query Neighborhood Hits	1371	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

ROR2_MOUSE
NC score	0.050316 (rank : 2171)	θ value	θ > 10 (rank : 2102)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1000	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

MAST4_HUMAN
NC score	0.050291 (rank : 2172)	θ value	θ > 10 (rank : 1899)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1804	Shared Neighborhood Hits	224
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MYT1_MOUSE
NC score	0.050284 (rank : 2173)	θ value	θ > 10 (rank : 1959)
Query Neighborhood Hits	1371	Target Neighborhood Hits	385	Shared Neighborhood Hits	170
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

PKN1_HUMAN
NC score	0.050253 (rank : 2174)	θ value	θ > 10 (rank : 2029)
Query Neighborhood Hits	1371	Target Neighborhood Hits	886	Shared Neighborhood Hits	116
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

CCD43_HUMAN
NC score	0.050178 (rank : 2175)	θ value	θ > 10 (rank : 1480)
Query Neighborhood Hits	1371	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q96MW1	Gene names	CCDC43
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

M4K1_MOUSE
NC score	0.050169 (rank : 2176)	θ value	θ > 10 (rank : 1897)
Query Neighborhood Hits	1371	Target Neighborhood Hits	858	Shared Neighborhood Hits	96
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

MP2K7_HUMAN
NC score	0.050152 (rank : 2177)	θ value	θ > 10 (rank : 1922)
Query Neighborhood Hits	1371	Target Neighborhood Hits	833	Shared Neighborhood Hits	94
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

GABP2_MOUSE
NC score	0.050114 (rank : 2178)	θ value	0.163984 (rank : 828)
Query Neighborhood Hits	1371	Target Neighborhood Hits	429	Shared Neighborhood Hits	128
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

FGFR2_MOUSE
NC score	0.050049 (rank : 2179)	θ value	θ > 10 (rank : 1671)
Query Neighborhood Hits	1371	Target Neighborhood Hits	1062	Shared Neighborhood Hits	97
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

ANPRA_MOUSE
NC score	0.050042 (rank : 2180)	θ value	θ > 10 (rank : 1410)
Query Neighborhood Hits	1371	Target Neighborhood Hits	600	Shared Neighborhood Hits	86
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

MERTK_HUMAN
NC score	0.050013 (rank : 2181)	θ value	θ > 10 (rank : 1906)
Query Neighborhood Hits	1371	Target Neighborhood Hits	988	Shared Neighborhood Hits	90
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

CC019_MOUSE
NC score	0.049534 (rank : 2182)	θ value	3.0926 (rank : 1166)
Query Neighborhood Hits	1371	Target Neighborhood Hits	61	Shared Neighborhood Hits	44
SwissProt Accessions	Q3U155, Q80XC8, Q8CA20	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf19 homolog.

RPTN_MOUSE
NC score	0.048833 (rank : 2183)	θ value	0.0193708 (rank : 669)
Query Neighborhood Hits	1371	Target Neighborhood Hits	650	Shared Neighborhood Hits	134
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

DACH1_HUMAN
NC score	0.048725 (rank : 2184)	θ value	5.27518 (rank : 1239)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

CALN1_MOUSE
NC score	0.048462 (rank : 2185)	θ value	0.365318 (rank : 895)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CALN1_HUMAN
NC score	0.048420 (rank : 2186)	θ value	0.365318 (rank : 894)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CABP7_HUMAN
NC score	0.047600 (rank : 2187)	θ value	0.47712 (rank : 931)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	46
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
NC score	0.047600 (rank : 2188)	θ value	0.47712 (rank : 932)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

TCOF_HUMAN
NC score	0.047082 (rank : 2189)	θ value	1.81305 (rank : 1114)
Query Neighborhood Hits	1371	Target Neighborhood Hits	543	Shared Neighborhood Hits	104
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

RIF1_MOUSE
NC score	0.046777 (rank : 2190)	θ value	5.27518 (rank : 1263)
Query Neighborhood Hits	1371	Target Neighborhood Hits	315	Shared Neighborhood Hits	104
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

TRIM6_MOUSE
NC score	0.046699 (rank : 2191)	θ value	6.88961 (rank : 1321)
Query Neighborhood Hits	1371	Target Neighborhood Hits	451	Shared Neighborhood Hits	193
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

LAD1_HUMAN
NC score	0.046664 (rank : 2192)	θ value	0.0252991 (rank : 681)
Query Neighborhood Hits	1371	Target Neighborhood Hits	441	Shared Neighborhood Hits	91
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

CALM_HUMAN
NC score	0.046647 (rank : 2193)	θ value	0.00298849 (rank : 546)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.046647 (rank : 2194)	θ value	0.00298849 (rank : 547)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

GIMA7_HUMAN
NC score	0.046370 (rank : 2195)	θ value	6.88961 (rank : 1298)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NHV1	Gene names	GIMAP7, IAN7
Domain Architecture	No domain graphic available
Description	GTPase, IMAP family member 7 (Immunity-associated nucleotide 7 protein).

CANB2_HUMAN
NC score	0.045988 (rank : 2196)	θ value	0.0193708 (rank : 656)
Query Neighborhood Hits	1371	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

TRIM6_HUMAN
NC score	0.045742 (rank : 2197)	θ value	1.81305 (rank : 1117)
Query Neighborhood Hits	1371	Target Neighborhood Hits	412	Shared Neighborhood Hits	163
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TMC2_MOUSE
NC score	0.045557 (rank : 2198)	θ value	0.813845 (rank : 999)
Query Neighborhood Hits	1371	Target Neighborhood Hits	249	Shared Neighborhood Hits	100
SwissProt Accessions	Q8R4P4	Gene names	Tmc2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

TFAM_HUMAN
NC score	0.045454 (rank : 2199)	θ value	6.88961 (rank : 1320)
Query Neighborhood Hits	1371	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

SNX16_HUMAN
NC score	0.045246 (rank : 2200)	θ value	8.99809 (rank : 1361)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	P57768, Q8N4U3	Gene names	SNX16
Domain Architecture
Description	Sorting nexin-16.

CSKI2_MOUSE
NC score	0.045122 (rank : 2201)	θ value	1.06291 (rank : 1009)
Query Neighborhood Hits	1371	Target Neighborhood Hits	812	Shared Neighborhood Hits	120
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

SEC63_HUMAN
NC score	0.045044 (rank : 2202)	θ value	2.36792 (rank : 1156)
Query Neighborhood Hits	1371	Target Neighborhood Hits	586	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

CANB1_HUMAN
NC score	0.045016 (rank : 2203)	θ value	0.00509761 (rank : 577)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	37
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
NC score	0.044994 (rank : 2204)	θ value	0.00509761 (rank : 578)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	37
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

BRDT_MOUSE
NC score	0.044471 (rank : 2205)	θ value	1.38821 (rank : 1042)
Query Neighborhood Hits	1371	Target Neighborhood Hits	243	Shared Neighborhood Hits	107
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

GON4L_HUMAN
NC score	0.043664 (rank : 2206)	θ value	6.88961 (rank : 1299)
Query Neighborhood Hits	1371	Target Neighborhood Hits	555	Shared Neighborhood Hits	132
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

PLDN_MOUSE
NC score	0.043294 (rank : 2207)	θ value	8.99809 (rank : 1354)
Query Neighborhood Hits	1371	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R0C0, Q3TUT4, Q91VG4	Gene names	Pldn, P2, Pa
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein) (Syntaxin 13-interacting protein).

PRVA_MOUSE
NC score	0.043044 (rank : 2208)	θ value	5.27518 (rank : 1259)
Query Neighborhood Hits	1371	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

FMN1A_MOUSE
NC score	0.042705 (rank : 2209)	θ value	5.27518 (rank : 1244)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	127
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

SN1L1_MOUSE
NC score	0.042458 (rank : 2210)	θ value	6.88961 (rank : 1318)
Query Neighborhood Hits	1371	Target Neighborhood Hits	895	Shared Neighborhood Hits	99
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

CANB2_MOUSE
NC score	0.041904 (rank : 2211)	θ value	0.163984 (rank : 823)
Query Neighborhood Hits	1371	Target Neighborhood Hits	173	Shared Neighborhood Hits	39
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

SEP10_MOUSE
NC score	0.041419 (rank : 2212)	θ value	1.06291 (rank : 1030)
Query Neighborhood Hits	1371	Target Neighborhood Hits	145	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

PDZD2_HUMAN
NC score	0.041268 (rank : 2213)	θ value	8.99809 (rank : 1351)
Query Neighborhood Hits	1371	Target Neighborhood Hits	772	Shared Neighborhood Hits	123
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

FMN1B_MOUSE
NC score	0.040811 (rank : 2214)	θ value	5.27518 (rank : 1245)
Query Neighborhood Hits	1371	Target Neighborhood Hits	447	Shared Neighborhood Hits	115
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

CDKL5_HUMAN
NC score	0.040567 (rank : 2215)	θ value	8.99809 (rank : 1327)
Query Neighborhood Hits	1371	Target Neighborhood Hits	967	Shared Neighborhood Hits	118
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CSKI2_HUMAN
NC score	0.040045 (rank : 2216)	θ value	1.06291 (rank : 1008)
Query Neighborhood Hits	1371	Target Neighborhood Hits	747	Shared Neighborhood Hits	105
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CALL3_HUMAN
NC score	0.040029 (rank : 2217)	θ value	0.0252991 (rank : 673)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	47
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

MIA2_MOUSE
NC score	0.039270 (rank : 2218)	θ value	0.813845 (rank : 984)
Query Neighborhood Hits	1371	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

EMIL1_HUMAN
NC score	0.038701 (rank : 2219)	θ value	0.0431538 (rank : 711)
Query Neighborhood Hits	1371	Target Neighborhood Hits	239	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

MK06_HUMAN
NC score	0.038457 (rank : 2220)	θ value	5.27518 (rank : 1253)
Query Neighborhood Hits	1371	Target Neighborhood Hits	815	Shared Neighborhood Hits	101
SwissProt Accessions	Q16659, Q68DH4, Q8IYN8	Gene names	MAPK6, ERK3, PRKM6
Domain Architecture
Description	Mitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97- MAPK).

SEP10_HUMAN
NC score	0.038012 (rank : 2221)	θ value	6.88961 (rank : 1316)
Query Neighborhood Hits	1371	Target Neighborhood Hits	161	Shared Neighborhood Hits	101
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

ZCPW1_MOUSE
NC score	0.037763 (rank : 2222)	θ value	5.27518 (rank : 1276)
Query Neighborhood Hits	1371	Target Neighborhood Hits	307	Shared Neighborhood Hits	79
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

CN140_HUMAN
NC score	0.037689 (rank : 2223)	θ value	6.88961 (rank : 1290)
Query Neighborhood Hits	1371	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q53FD0, Q9BTA8, Q9H5S9	Gene names	C14orf140
Domain Architecture	No domain graphic available
Description	Protein C14orf140.

SETD2_HUMAN
NC score	0.037464 (rank : 2224)	θ value	5.27518 (rank : 1266)
Query Neighborhood Hits	1371	Target Neighborhood Hits	412	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

NBR1_HUMAN
NC score	0.037340 (rank : 2225)	θ value	0.365318 (rank : 915)
Query Neighborhood Hits	1371	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

ASPM_MOUSE
NC score	0.036417 (rank : 2226)	θ value	6.88961 (rank : 1282)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

IF37_MOUSE
NC score	0.035658 (rank : 2227)	θ value	4.03905 (rank : 1206)
Query Neighborhood Hits	1371	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	O70194	Gene names	Eif3s7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).

CN094_MOUSE
NC score	0.035437 (rank : 2228)	θ value	1.81305 (rank : 1084)
Query Neighborhood Hits	1371	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BFT2, Q99KI1	Gene names	D14Ertd500e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf94 homolog.

TR150_HUMAN
NC score	0.035425 (rank : 2229)	θ value	1.38821 (rank : 1072)
Query Neighborhood Hits	1371	Target Neighborhood Hits	313	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

CA026_MOUSE
NC score	0.035285 (rank : 2230)	θ value	1.38821 (rank : 1043)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

TRI35_HUMAN
NC score	0.034828 (rank : 2231)	θ value	3.0926 (rank : 1189)
Query Neighborhood Hits	1371	Target Neighborhood Hits	382	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

INOC1_HUMAN
NC score	0.034640 (rank : 2232)	θ value	1.81305 (rank : 1092)
Query Neighborhood Hits	1371	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

CETN3_MOUSE
NC score	0.034564 (rank : 2233)	θ value	1.38821 (rank : 1046)
Query Neighborhood Hits	1371	Target Neighborhood Hits	208	Shared Neighborhood Hits	47
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

EMIL1_MOUSE
NC score	0.034526 (rank : 2234)	θ value	0.0961366 (rank : 780)
Query Neighborhood Hits	1371	Target Neighborhood Hits	214	Shared Neighborhood Hits	66
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

OPA1_HUMAN
NC score	0.034513 (rank : 2235)	θ value	0.279714 (rank : 884)
Query Neighborhood Hits	1371	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

NBR1_MOUSE
NC score	0.034505 (rank : 2236)	θ value	0.47712 (rank : 947)
Query Neighborhood Hits	1371	Target Neighborhood Hits	116	Shared Neighborhood Hits	36
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

MEFV_HUMAN
NC score	0.034500 (rank : 2237)	θ value	3.0926 (rank : 1182)
Query Neighborhood Hits	1371	Target Neighborhood Hits	431	Shared Neighborhood Hits	146
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

CETN3_HUMAN
NC score	0.034248 (rank : 2238)	θ value	1.38821 (rank : 1045)
Query Neighborhood Hits	1371	Target Neighborhood Hits	211	Shared Neighborhood Hits	48
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CN044_MOUSE
NC score	0.033054 (rank : 2239)	θ value	2.36792 (rank : 1127)
Query Neighborhood Hits	1371	Target Neighborhood Hits	57	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CB59, Q8BQX8, Q8BSL9, Q8CBZ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44 homolog.

S3TC2_HUMAN
NC score	0.033033 (rank : 2240)	θ value	5.27518 (rank : 1265)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TF17, Q9H8I5	Gene names	SH3TC2, KIAA1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

CETN1_HUMAN
NC score	0.032870 (rank : 2241)	θ value	5.27518 (rank : 1237)
Query Neighborhood Hits	1371	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CTNA1_HUMAN
NC score	0.032758 (rank : 2242)	θ value	0.365318 (rank : 903)
Query Neighborhood Hits	1371	Target Neighborhood Hits	83	Shared Neighborhood Hits	50
SwissProt Accessions	P35221, Q12795	Gene names	CTNNA1
Domain Architecture
Description	Catenin alpha-1 (Cadherin-associated protein) (Alpha E-catenin) (NY- REN-13 antigen).

INOC1_MOUSE
NC score	0.032097 (rank : 2243)	θ value	1.81305 (rank : 1093)
Query Neighborhood Hits	1371	Target Neighborhood Hits	178	Shared Neighborhood Hits	96
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

CABP2_HUMAN
NC score	0.031438 (rank : 2244)	θ value	1.81305 (rank : 1079)
Query Neighborhood Hits	1371	Target Neighborhood Hits	205	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP5_MOUSE
NC score	0.031131 (rank : 2245)	θ value	2.36792 (rank : 1125)
Query Neighborhood Hits	1371	Target Neighborhood Hits	207	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CTNA1_MOUSE
NC score	0.031037 (rank : 2246)	θ value	0.365318 (rank : 904)
Query Neighborhood Hits	1371	Target Neighborhood Hits	84	Shared Neighborhood Hits	49
SwissProt Accessions	P26231	Gene names	Ctnna1, Catna1
Domain Architecture
Description	Catenin alpha-1 (102 kDa cadherin-associated protein) (CAP102) (Alpha E-catenin).

CABP4_MOUSE
NC score	0.030900 (rank : 2247)	θ value	6.88961 (rank : 1285)
Query Neighborhood Hits	1371	Target Neighborhood Hits	212	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

OPA1_MOUSE
NC score	0.030867 (rank : 2248)	θ value	0.365318 (rank : 919)
Query Neighborhood Hits	1371	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

HSP7C_MOUSE
NC score	0.030770 (rank : 2249)	θ value	0.279714 (rank : 881)
Query Neighborhood Hits	1371	Target Neighborhood Hits	166	Shared Neighborhood Hits	95
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

ITCH_MOUSE
NC score	0.030615 (rank : 2250)	θ value	4.03905 (rank : 1207)
Query Neighborhood Hits	1371	Target Neighborhood Hits	127	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

TRIM7_HUMAN
NC score	0.030609 (rank : 2251)	θ value	0.125558 (rank : 817)
Query Neighborhood Hits	1371	Target Neighborhood Hits	336	Shared Neighborhood Hits	108
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

RBM6_HUMAN
NC score	0.030370 (rank : 2252)	θ value	2.36792 (rank : 1153)
Query Neighborhood Hits	1371	Target Neighborhood Hits	221	Shared Neighborhood Hits	48
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

CABP2_MOUSE
NC score	0.030196 (rank : 2253)	θ value	2.36792 (rank : 1124)
Query Neighborhood Hits	1371	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP3_HUMAN
NC score	0.029700 (rank : 2254)	θ value	6.88961 (rank : 1284)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP5_HUMAN
NC score	0.029177 (rank : 2255)	θ value	6.88961 (rank : 1286)
Query Neighborhood Hits	1371	Target Neighborhood Hits	197	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CPSF3_MOUSE
NC score	0.028569 (rank : 2256)	θ value	0.365318 (rank : 900)
Query Neighborhood Hits	1371	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXK7	Gene names	Cpsf3, Cpsf73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

TRI68_MOUSE
NC score	0.028564 (rank : 2257)	θ value	1.06291 (rank : 1037)
Query Neighborhood Hits	1371	Target Neighborhood Hits	356	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

CPSF3_HUMAN
NC score	0.028532 (rank : 2258)	θ value	0.365318 (rank : 899)
Query Neighborhood Hits	1371	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKF6, O14769, Q96F36	Gene names	CPSF3, CPSF73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

IF2M_MOUSE
NC score	0.028135 (rank : 2259)	θ value	8.99809 (rank : 1332)
Query Neighborhood Hits	1371	Target Neighborhood Hits	183	Shared Neighborhood Hits	77
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

ITCH_HUMAN
NC score	0.027565 (rank : 2260)	θ value	8.99809 (rank : 1333)
Query Neighborhood Hits	1371	Target Neighborhood Hits	162	Shared Neighborhood Hits	40
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

HSP7C_HUMAN
NC score	0.027446 (rank : 2261)	θ value	0.279714 (rank : 880)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	81
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

PERF_HUMAN
NC score	0.026795 (rank : 2262)	θ value	8.99809 (rank : 1352)
Query Neighborhood Hits	1371	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

TRI60_HUMAN
NC score	0.026464 (rank : 2263)	θ value	4.03905 (rank : 1227)
Query Neighborhood Hits	1371	Target Neighborhood Hits	357	Shared Neighborhood Hits	108
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

SEC62_HUMAN
NC score	0.026147 (rank : 2264)	θ value	4.03905 (rank : 1222)
Query Neighborhood Hits	1371	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

PESC_HUMAN
NC score	0.025096 (rank : 2265)	θ value	6.88961 (rank : 1308)
Query Neighborhood Hits	1371	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	O00541, Q6IC29	Gene names	PES1
Domain Architecture
Description	Pescadillo homolog 1.

CPSF2_MOUSE
NC score	0.024838 (rank : 2266)	θ value	1.06291 (rank : 1007)
Query Neighborhood Hits	1371	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	O35218	Gene names	Cpsf2, Cpsf100, Mcpsf
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

CPSF2_HUMAN
NC score	0.024659 (rank : 2267)	θ value	1.06291 (rank : 1006)
Query Neighborhood Hits	1371	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

LMD1_HUMAN
NC score	0.024574 (rank : 2268)	θ value	4.03905 (rank : 1213)
Query Neighborhood Hits	1371	Target Neighborhood Hits	169	Shared Neighborhood Hits	52
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

DGKK_HUMAN
NC score	0.024168 (rank : 2269)	θ value	5.27518 (rank : 1240)
Query Neighborhood Hits	1371	Target Neighborhood Hits	378	Shared Neighborhood Hits	67
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

IF37_HUMAN
NC score	0.024128 (rank : 2270)	θ value	4.03905 (rank : 1205)
Query Neighborhood Hits	1371	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O15371, Q5M9Q6	Gene names	EIF3S7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).

ADDB_MOUSE
NC score	0.023833 (rank : 2271)	θ value	8.99809 (rank : 1325)
Query Neighborhood Hits	1371	Target Neighborhood Hits	574	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

HSP76_HUMAN
NC score	0.023304 (rank : 2272)	θ value	0.0961366 (rank : 784)
Query Neighborhood Hits	1371	Target Neighborhood Hits	128	Shared Neighborhood Hits	79
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

PICA_MOUSE
NC score	0.022994 (rank : 2273)	θ value	1.38821 (rank : 1064)
Query Neighborhood Hits	1371	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

ANGL2_MOUSE
NC score	0.022975 (rank : 2274)	θ value	1.38821 (rank : 1041)
Query Neighborhood Hits	1371	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

P52K_HUMAN
NC score	0.022852 (rank : 2275)	θ value	2.36792 (rank : 1151)
Query Neighborhood Hits	1371	Target Neighborhood Hits	142	Shared Neighborhood Hits	52
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

CPLX3_MOUSE
NC score	0.022835 (rank : 2276)	θ value	3.0926 (rank : 1169)
Query Neighborhood Hits	1371	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R1B5, Q96AW7	Gene names	Cplx3
Domain Architecture	No domain graphic available
Description	Complexin-3 (Complexin III) (CPX III).

CPLX3_HUMAN
NC score	0.022748 (rank : 2277)	θ value	3.0926 (rank : 1168)
Query Neighborhood Hits	1371	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WVH0, Q8TEM6, Q9H818	Gene names	CPLX3
Domain Architecture	No domain graphic available
Description	Complexin-3 (Complexin III) (CPX III).

METL4_HUMAN
NC score	0.022394 (rank : 2278)	θ value	0.21417 (rank : 851)
Query Neighborhood Hits	1371	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N3J2, Q2TAA7, Q9H5U9	Gene names	METTL4
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 4 (EC 2.1.1.-).

IF39_HUMAN
NC score	0.022204 (rank : 2279)	θ value	6.88961 (rank : 1300)
Query Neighborhood Hits	1371	Target Neighborhood Hits	187	Shared Neighborhood Hits	34
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

ANGL2_HUMAN
NC score	0.021936 (rank : 2280)	θ value	1.38821 (rank : 1040)
Query Neighborhood Hits	1371	Target Neighborhood Hits	104	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

MYST4_MOUSE
NC score	0.021925 (rank : 2281)	θ value	5.27518 (rank : 1254)
Query Neighborhood Hits	1371	Target Neighborhood Hits	416	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

SIN3B_MOUSE
NC score	0.021419 (rank : 2282)	θ value	0.813845 (rank : 997)
Query Neighborhood Hits	1371	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	Q62141, O54976, Q6A013, Q8VCB8, Q8VDZ5	Gene names	Sin3b, Kiaa0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

CGAT2_HUMAN
NC score	0.021405 (rank : 2283)	θ value	0.0563607 (rank : 726)
Query Neighborhood Hits	1371	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N6G5, Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6	Gene names	GALNACT2, CHGN2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

GRP75_HUMAN
NC score	0.020707 (rank : 2284)	θ value	3.0926 (rank : 1174)
Query Neighborhood Hits	1371	Target Neighborhood Hits	97	Shared Neighborhood Hits	52
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

RP9_HUMAN
NC score	0.020674 (rank : 2285)	θ value	4.03905 (rank : 1221)
Query Neighborhood Hits	1371	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TA86	Gene names	RP9
Domain Architecture	No domain graphic available
Description	Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1).

BBX_HUMAN
NC score	0.020292 (rank : 2286)	θ value	2.36792 (rank : 1121)
Query Neighborhood Hits	1371	Target Neighborhood Hits	167	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

PICAL_HUMAN
NC score	0.019984 (rank : 2287)	θ value	1.38821 (rank : 1063)
Query Neighborhood Hits	1371	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

SIN3B_HUMAN
NC score	0.019464 (rank : 2288)	θ value	0.813845 (rank : 996)
Query Neighborhood Hits	1371	Target Neighborhood Hits	82	Shared Neighborhood Hits	30
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

TCF20_MOUSE
NC score	0.019419 (rank : 2289)	θ value	6.88961 (rank : 1319)
Query Neighborhood Hits	1371	Target Neighborhood Hits	396	Shared Neighborhood Hits	70
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

MXI1_MOUSE
NC score	0.018870 (rank : 2290)	θ value	8.99809 (rank : 1343)
Query Neighborhood Hits	1371	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

TRIM4_HUMAN
NC score	0.018817 (rank : 2291)	θ value	5.27518 (rank : 1273)
Query Neighborhood Hits	1371	Target Neighborhood Hits	321	Shared Neighborhood Hits	73
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

KIFA3_MOUSE
NC score	0.018243 (rank : 2292)	θ value	3.0926 (rank : 1179)
Query Neighborhood Hits	1371	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

KIFA3_HUMAN
NC score	0.018111 (rank : 2293)	θ value	3.0926 (rank : 1178)
Query Neighborhood Hits	1371	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

JHD2C_HUMAN
NC score	0.017634 (rank : 2294)	θ value	8.99809 (rank : 1334)
Query Neighborhood Hits	1371	Target Neighborhood Hits	279	Shared Neighborhood Hits	80
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

LRRC6_HUMAN
NC score	0.016983 (rank : 2295)	θ value	8.99809 (rank : 1341)
Query Neighborhood Hits	1371	Target Neighborhood Hits	181	Shared Neighborhood Hits	46
SwissProt Accessions	Q86X45, Q13648, Q4G183	Gene names	LRRC6, LRTP, TSLRP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

SMOC1_HUMAN
NC score	0.015952 (rank : 2296)	θ value	1.06291 (rank : 1033)
Query Neighborhood Hits	1371	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

TTC5_HUMAN
NC score	0.015180 (rank : 2297)	θ value	4.03905 (rank : 1228)
Query Neighborhood Hits	1371	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N0Z6	Gene names	TTC5
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 5 (TPR repeat protein 5).

AFF2_MOUSE
NC score	0.015146 (rank : 2298)	θ value	6.88961 (rank : 1280)
Query Neighborhood Hits	1371	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

ATM_MOUSE
NC score	0.015009 (rank : 2299)	θ value	8.99809 (rank : 1326)
Query Neighborhood Hits	1371	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q62388	Gene names	Atm
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).

RPOM_MOUSE
NC score	0.014814 (rank : 2300)	θ value	6.88961 (rank : 1314)
Query Neighborhood Hits	1371	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BKF1, Q8BJE0	Gene names	Polrmt
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase, mitochondrial precursor (EC 2.7.7.6) (MtRPOL).

RHBD4_HUMAN
NC score	0.014682 (rank : 2301)	θ value	3.0926 (rank : 1184)
Query Neighborhood Hits	1371	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	P58872	Gene names	RHBDL4, VRHO
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

CHD9_HUMAN
NC score	0.014486 (rank : 2302)	θ value	1.38821 (rank : 1048)
Query Neighborhood Hits	1371	Target Neighborhood Hits	343	Shared Neighborhood Hits	88
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

TDRD7_HUMAN
NC score	0.013919 (rank : 2303)	θ value	0.21417 (rank : 866)
Query Neighborhood Hits	1371	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NHU6, Q96JT1, Q9UFF0, Q9Y2M3	Gene names	TDRD7, PCTAIRE2BP
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

RHBD4_MOUSE
NC score	0.013412 (rank : 2304)	θ value	5.27518 (rank : 1261)
Query Neighborhood Hits	1371	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P58873	Gene names	Rhbdl4, Vrho
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

CRSP2_HUMAN
NC score	0.012962 (rank : 2305)	θ value	6.88961 (rank : 1293)
Query Neighborhood Hits	1371	Target Neighborhood Hits	380	Shared Neighborhood Hits	41
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

SPG16_HUMAN
NC score	0.012843 (rank : 2306)	θ value	1.81305 (rank : 1111)
Query Neighborhood Hits	1371	Target Neighborhood Hits	361	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

PER2_MOUSE
NC score	0.012578 (rank : 2307)	θ value	1.06291 (rank : 1025)
Query Neighborhood Hits	1371	Target Neighborhood Hits	325	Shared Neighborhood Hits	50
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

RBM5_MOUSE
NC score	0.012388 (rank : 2308)	θ value	6.88961 (rank : 1312)
Query Neighborhood Hits	1371	Target Neighborhood Hits	216	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YE7, Q3UZ19, Q99KV9	Gene names	Rbm5, Luca15
Domain Architecture	No domain graphic available
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15).

DHX36_MOUSE
NC score	0.011995 (rank : 2309)	θ value	4.03905 (rank : 1203)
Query Neighborhood Hits	1371	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

PDCL2_HUMAN
NC score	0.011544 (rank : 2310)	θ value	5.27518 (rank : 1256)
Query Neighborhood Hits	1371	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N4E4	Gene names	PDCL2
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 2.

CN120_HUMAN
NC score	0.011392 (rank : 2311)	θ value	6.88961 (rank : 1289)
Query Neighborhood Hits	1371	Target Neighborhood Hits	25	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEJ9, Q9Y400	Gene names	C14orf120
Domain Architecture
Description	Protein C14orf120.

JADE3_MOUSE
NC score	0.011360 (rank : 2312)	θ value	2.36792 (rank : 1141)
Query Neighborhood Hits	1371	Target Neighborhood Hits	174	Shared Neighborhood Hits	43
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

UBE4A_HUMAN
NC score	0.011108 (rank : 2313)	θ value	5.27518 (rank : 1274)
Query Neighborhood Hits	1371	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q14139, Q6P5T4, Q7Z639	Gene names	UBE4A, KIAA0126
Domain Architecture	No domain graphic available
Description	Ubiquitin conjugation factor E4 A.

DDX49_HUMAN
NC score	0.010981 (rank : 2314)	θ value	4.03905 (rank : 1202)
Query Neighborhood Hits	1371	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

YYAP1_HUMAN
NC score	0.010266 (rank : 2315)	θ value	6.88961 (rank : 1324)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H869, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, Q8IXA6, Q8TEW5, Q8TF04, Q96HB6, Q9BQ64, Q9NV84	Gene names	YY1AP1, HCCA2, YY1AP
Domain Architecture	No domain graphic available
Description	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2).

STAG3_HUMAN
NC score	0.010158 (rank : 2316)	θ value	1.06291 (rank : 1034)
Query Neighborhood Hits	1371	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

SETB1_MOUSE
NC score	0.010097 (rank : 2317)	θ value	6.88961 (rank : 1317)
Query Neighborhood Hits	1371	Target Neighborhood Hits	150	Shared Neighborhood Hits	36
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

RCAS1_HUMAN
NC score	0.008677 (rank : 2318)	θ value	6.88961 (rank : 1313)
Query Neighborhood Hits	1371	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	O00559, Q6IB20, Q9BS76	Gene names	EBAG9, RCAS1
Domain Architecture	No domain graphic available
Description	Receptor-binding cancer antigen expressed on SiSo cells (Cancer- associated surface antigen RCAS1) (Estrogen receptor-binding fragment- associated gene 9 protein).

RCOR2_HUMAN
NC score	0.008606 (rank : 2319)	θ value	1.06291 (rank : 1028)
Query Neighborhood Hits	1371	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

IFRD1_HUMAN
NC score	0.008101 (rank : 2320)	θ value	5.27518 (rank : 1247)
Query Neighborhood Hits	1371	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O00458, O75234, Q5U013, Q9BVE4	Gene names	IFRD1
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4).

MITF_HUMAN
NC score	0.007996 (rank : 2321)	θ value	6.88961 (rank : 1305)
Query Neighborhood Hits	1371	Target Neighborhood Hits	113	Shared Neighborhood Hits	25
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MNDA_HUMAN
NC score	0.007706 (rank : 2322)	θ value	8.99809 (rank : 1342)
Query Neighborhood Hits	1371	Target Neighborhood Hits	76	Shared Neighborhood Hits	27
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

RCOR2_MOUSE
NC score	0.006136 (rank : 2323)	θ value	8.99809 (rank : 1357)
Query Neighborhood Hits	1371	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

OVGP1_HUMAN
NC score	0.006112 (rank : 2324)	θ value	0.279714 (rank : 885)
Query Neighborhood Hits	1371	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

P73L_HUMAN
NC score	0.005885 (rank : 2325)	θ value	8.99809 (rank : 1349)
Query Neighborhood Hits	1371	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

CU005_HUMAN
NC score	0.005658 (rank : 2326)	θ value	8.99809 (rank : 1328)
Query Neighborhood Hits	1371	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3R5, Q9UEZ3	Gene names	C21orf5, KIAA0933
Domain Architecture
Description	Protein C21orf5.

STXB1_HUMAN
NC score	0.005433 (rank : 2327)	θ value	4.03905 (rank : 1223)
Query Neighborhood Hits	1371	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	P61764, Q28208, Q62759, Q64320, Q96TG8	Gene names	STXBP1, UNC18A
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1) (N- Sec1) (p67).

STXB1_MOUSE
NC score	0.005433 (rank : 2328)	θ value	4.03905 (rank : 1224)
Query Neighborhood Hits	1371	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	O08599, Q8VD51	Gene names	Stxbp1
Domain Architecture
Description	Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18A) (Unc-18-1).

P73L_MOUSE
NC score	0.005243 (rank : 2329)	θ value	8.99809 (rank : 1350)
Query Neighborhood Hits	1371	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).

LAP2_MOUSE
NC score	0.004811 (rank : 2330)	θ value	3.0926 (rank : 1180)
Query Neighborhood Hits	1371	Target Neighborhood Hits	482	Shared Neighborhood Hits	59
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

DMRTA_HUMAN
NC score	0.003577 (rank : 2331)	θ value	6.88961 (rank : 1295)
Query Neighborhood Hits	1371	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

CAC1B_HUMAN
NC score	0.003273 (rank : 2332)	θ value	1.81305 (rank : 1080)
Query Neighborhood Hits	1371	Target Neighborhood Hits	257	Shared Neighborhood Hits	38
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

HHEX_HUMAN
NC score	0.002835 (rank : 2333)	θ value	0.0961366 (rank : 783)
Query Neighborhood Hits	1371	Target Neighborhood Hits	358	Shared Neighborhood Hits	28
SwissProt Accessions	Q03014	Gene names	HHEX, HEX, PRH, PRHX
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

ADA30_HUMAN
NC score	0.002791 (rank : 2334)	θ value	1.38821 (rank : 1039)
Query Neighborhood Hits	1371	Target Neighborhood Hits	391	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CAC1B_MOUSE
NC score	0.002586 (rank : 2335)	θ value	4.03905 (rank : 1198)
Query Neighborhood Hits	1371	Target Neighborhood Hits	351	Shared Neighborhood Hits	43
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

RNF31_HUMAN
NC score	0.001598 (rank : 2336)	θ value	8.99809 (rank : 1359)
Query Neighborhood Hits	1371	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

DCJ11_HUMAN
NC score	0.001432 (rank : 2337)	θ value	8.99809 (rank : 1329)
Query Neighborhood Hits	1371	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NVH1, Q4VWF5, Q5VZN0, Q6PK20, Q6PK70, Q8NDM2, Q96CL7	Gene names	DNAJC11
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 11.

KLRA2_MOUSE
NC score	0.001367 (rank : 2338)	θ value	8.99809 (rank : 1339)
Query Neighborhood Hits	1371	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q60660	Gene names	Klra2, Ly49-b, Ly49b
Domain Architecture
Description	Killer cell lectin-like receptor 2 (T-cell surface glycoprotein Ly- 49B) (Ly49-B antigen) (Lymphocyte antigen 49B).

ACADL_MOUSE
NC score	0.000848 (rank : 2339)	θ value	2.36792 (rank : 1118)
Query Neighborhood Hits	1371	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P51174, O35302, Q8QZR6, Q9CU29, Q9DB83	Gene names	Acadl
Domain Architecture
Description	Long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.13) (LCAD).

TXND3_HUMAN
NC score	0.000846 (rank : 2340)	θ value	8.99809 (rank : 1366)
Query Neighborhood Hits	1371	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

DPP10_HUMAN
NC score	-0.000051 (rank : 2341)	θ value	5.27518 (rank : 1242)
Query Neighborhood Hits	1371	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

GPR98_MOUSE
NC score	-0.000095 (rank : 2342)	θ value	1.38821 (rank : 1053)
Query Neighborhood Hits	1371	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

AHR_HUMAN
NC score	-0.000676 (rank : 2343)	θ value	6.88961 (rank : 1281)
Query Neighborhood Hits	1371	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

ADCY6_HUMAN
NC score	-0.002050 (rank : 2344)	θ value	4.03905 (rank : 1192)
Query Neighborhood Hits	1371	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	O43306, Q9NR75	Gene names	ADCY6, KIAA0422
Domain Architecture
Description	Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6) (Ca(2+)-inhibitable adenylyl cyclase).

DDX20_HUMAN
NC score	-0.002602 (rank : 2345)	θ value	2.36792 (rank : 1132)
Query Neighborhood Hits	1371	Target Neighborhood Hits	121	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

LRC47_MOUSE
NC score	-0.004190 (rank : 2346)	θ value	1.38821 (rank : 1056)
Query Neighborhood Hits	1371	Target Neighborhood Hits	299	Shared Neighborhood Hits	11
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

HHEX_MOUSE
NC score	-0.005278 (rank : 2347)	θ value	2.36792 (rank : 1139)
Query Neighborhood Hits	1371	Target Neighborhood Hits	350	Shared Neighborhood Hits	17
SwissProt Accessions	P43120	Gene names	Hhex, Prhx
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

PCD15_HUMAN
NC score	-0.006009 (rank : 2348)	θ value	4.03905 (rank : 1217)
Query Neighborhood Hits	1371	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

MEOX1_HUMAN
NC score	-0.006160 (rank : 2349)	θ value	2.36792 (rank : 1148)
Query Neighborhood Hits	1371	Target Neighborhood Hits	342	Shared Neighborhood Hits	15
SwissProt Accessions	P50221	Gene names	MEOX1, MOX1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

PTPRZ_HUMAN
NC score	-0.007264 (rank : 2350)	θ value	4.03905 (rank : 1219)
Query Neighborhood Hits	1371	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

MEOX1_MOUSE
NC score	-0.007476 (rank : 2351)	θ value	1.81305 (rank : 1100)
Query Neighborhood Hits	1371	Target Neighborhood Hits	345	Shared Neighborhood Hits	12
SwissProt Accessions	P32442	Gene names	Meox1, Mox-1, Mox1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

RX_HUMAN
NC score	-0.009516 (rank : 2352)	θ value	3.0926 (rank : 1185)
Query Neighborhood Hits	1371	Target Neighborhood Hits	423	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

ECM2_HUMAN
NC score	-0.009605 (rank : 2353)	θ value	2.36792 (rank : 1134)
Query Neighborhood Hits	1371	Target Neighborhood Hits	402	Shared Neighborhood Hits	28
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

PEG3_HUMAN
NC score	-0.019534 (rank : 2354)	θ value	0.279714 (rank : 887)
Query Neighborhood Hits	1371	Target Neighborhood Hits	800	Shared Neighborhood Hits	28
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

ZN148_HUMAN
NC score	-0.023660 (rank : 2355)	θ value	3.0926 (rank : 1190)
Query Neighborhood Hits	1371	Target Neighborhood Hits	747	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQR1, O00389, O43591	Gene names	ZNF148, ZBP89
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89).

ZN148_MOUSE
NC score	-0.023836 (rank : 2356)	θ value	8.99809 (rank : 1369)
Query Neighborhood Hits	1371	Target Neighborhood Hits	755	Shared Neighborhood Hits	19
SwissProt Accessions	Q61624, P97475	Gene names	Znf148, Zbp89, Zfp148
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89) (G-rich box-binding protein) (Beta enolase repressor factor 1) (Transcription factor BFCOL1).

ZN546_HUMAN
NC score	-0.024103 (rank : 2357)	θ value	3.0926 (rank : 1191)
Query Neighborhood Hits	1371	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UE3	Gene names	ZNF546, ZNF49
Domain Architecture	No domain graphic available
Description	Zinc finger protein 546.