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Network neighborhood for query Sequence : CAC1B_MOUSE

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CAC1B_MOUSE
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1A_HUMAN
θ value	0 (rank : 1)	NC score	0.968587 (rank : 6)
Query Neighborhood Hits	351	Target Neighborhood Hits	387	Shared Neighborhood Hits	117
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	0 (rank : 2)	NC score	0.978448 (rank : 3)
Query Neighborhood Hits	351	Target Neighborhood Hits	267	Shared Neighborhood Hits	97
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
θ value	0 (rank : 3)	NC score	0.988419 (rank : 2)
Query Neighborhood Hits	351	Target Neighborhood Hits	257	Shared Neighborhood Hits	152
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	351	Target Neighborhood Hits	351	Shared Neighborhood Hits	351
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_HUMAN
θ value	0 (rank : 5)	NC score	0.947621 (rank : 13)
Query Neighborhood Hits	351	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
θ value	0 (rank : 6)	NC score	0.949188 (rank : 12)
Query Neighborhood Hits	351	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	0 (rank : 7)	NC score	0.951249 (rank : 10)
Query Neighborhood Hits	351	Target Neighborhood Hits	118	Shared Neighborhood Hits	63
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1E_HUMAN
θ value	0 (rank : 8)	NC score	0.973819 (rank : 4)
Query Neighborhood Hits	351	Target Neighborhood Hits	148	Shared Neighborhood Hits	74
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	0 (rank : 9)	NC score	0.973342 (rank : 5)
Query Neighborhood Hits	351	Target Neighborhood Hits	167	Shared Neighborhood Hits	74
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1F_HUMAN
θ value	0 (rank : 10)	NC score	0.951368 (rank : 9)
Query Neighborhood Hits	351	Target Neighborhood Hits	141	Shared Neighborhood Hits	66
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	0 (rank : 11)	NC score	0.951216 (rank : 11)
Query Neighborhood Hits	351	Target Neighborhood Hits	142	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	0 (rank : 12)	NC score	0.952583 (rank : 8)
Query Neighborhood Hits	351	Target Neighborhood Hits	92	Shared Neighborhood Hits	63
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
θ value	0 (rank : 13)	NC score	0.953077 (rank : 7)
Query Neighborhood Hits	351	Target Neighborhood Hits	98	Shared Neighborhood Hits	65
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN2A_HUMAN
θ value	8.81223e-72 (rank : 14)	NC score	0.842327 (rank : 26)
Query Neighborhood Hits	351	Target Neighborhood Hits	157	Shared Neighborhood Hits	54
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN9A_HUMAN
θ value	1.96316e-71 (rank : 15)	NC score	0.842207 (rank : 27)
Query Neighborhood Hits	351	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN1A_HUMAN
θ value	1.66191e-70 (rank : 16)	NC score	0.841975 (rank : 28)
Query Neighborhood Hits	351	Target Neighborhood Hits	148	Shared Neighborhood Hits	61
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1I_HUMAN
θ value	3.13423e-69 (rank : 17)	NC score	0.892839 (rank : 14)
Query Neighborhood Hits	351	Target Neighborhood Hits	138	Shared Neighborhood Hits	71
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SCN3A_HUMAN
θ value	9.11921e-69 (rank : 18)	NC score	0.844276 (rank : 24)
Query Neighborhood Hits	351	Target Neighborhood Hits	115	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN4A_HUMAN
θ value	2.03155e-68 (rank : 19)	NC score	0.852725 (rank : 21)
Query Neighborhood Hits	351	Target Neighborhood Hits	133	Shared Neighborhood Hits	66
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN8A_MOUSE
θ value	2.03155e-68 (rank : 20)	NC score	0.840695 (rank : 29)
Query Neighborhood Hits	351	Target Neighborhood Hits	136	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_HUMAN
θ value	7.71989e-68 (rank : 21)	NC score	0.843001 (rank : 25)
Query Neighborhood Hits	351	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN5A_HUMAN
θ value	1.00825e-67 (rank : 22)	NC score	0.853561 (rank : 20)
Query Neighborhood Hits	351	Target Neighborhood Hits	145	Shared Neighborhood Hits	59
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1H_MOUSE
θ value	1.31681e-67 (rank : 23)	NC score	0.871780 (rank : 15)
Query Neighborhood Hits	351	Target Neighborhood Hits	230	Shared Neighborhood Hits	93
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

SC11A_HUMAN
θ value	1.31681e-67 (rank : 24)	NC score	0.858448 (rank : 18)
Query Neighborhood Hits	351	Target Neighborhood Hits	111	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

CAC1G_HUMAN
θ value	2.93355e-67 (rank : 25)	NC score	0.858435 (rank : 19)
Query Neighborhood Hits	351	Target Neighborhood Hits	587	Shared Neighborhood Hits	139
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_HUMAN
θ value	3.83135e-67 (rank : 26)	NC score	0.867457 (rank : 16)
Query Neighborhood Hits	351	Target Neighborhood Hits	307	Shared Neighborhood Hits	93
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC10A_MOUSE
θ value	3.83135e-67 (rank : 27)	NC score	0.844288 (rank : 23)
Query Neighborhood Hits	351	Target Neighborhood Hits	107	Shared Neighborhood Hits	64
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC10A_HUMAN
θ value	8.83269e-64 (rank : 28)	NC score	0.839589 (rank : 30)
Query Neighborhood Hits	351	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SC11A_MOUSE
θ value	5.7252e-63 (rank : 29)	NC score	0.858806 (rank : 17)
Query Neighborhood Hits	351	Target Neighborhood Hits	116	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN7A_HUMAN
θ value	8.85319e-56 (rank : 30)	NC score	0.850112 (rank : 22)
Query Neighborhood Hits	351	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

PKD2_MOUSE
θ value	1.09739e-05 (rank : 31)	NC score	0.332206 (rank : 34)
Query Neighborhood Hits	351	Target Neighborhood Hits	99	Shared Neighborhood Hits	45
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PK2L2_HUMAN
θ value	4.1701e-05 (rank : 32)	NC score	0.368093 (rank : 31)
Query Neighborhood Hits	351	Target Neighborhood Hits	90	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
θ value	5.44631e-05 (rank : 33)	NC score	0.342641 (rank : 32)
Query Neighborhood Hits	351	Target Neighborhood Hits	132	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PKD2_HUMAN
θ value	9.29e-05 (rank : 34)	NC score	0.319561 (rank : 35)
Query Neighborhood Hits	351	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNV2_HUMAN
θ value	0.00035302 (rank : 35)	NC score	0.240217 (rank : 37)
Query Neighborhood Hits	351	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCND1_MOUSE
θ value	0.000461057 (rank : 36)	NC score	0.183439 (rank : 47)
Query Neighborhood Hits	351	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

PK2L2_MOUSE
θ value	0.000461057 (rank : 37)	NC score	0.334611 (rank : 33)
Query Neighborhood Hits	351	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCND2_HUMAN
θ value	0.00102713 (rank : 38)	NC score	0.192667 (rank : 46)
Query Neighborhood Hits	351	Target Neighborhood Hits	154	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.00102713 (rank : 39)	NC score	0.192833 (rank : 45)
Query Neighborhood Hits	351	Target Neighborhood Hits	156	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_HUMAN
θ value	0.00102713 (rank : 40)	NC score	0.198480 (rank : 44)
Query Neighborhood Hits	351	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.00102713 (rank : 41)	NC score	0.198597 (rank : 43)
Query Neighborhood Hits	351	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNF1_HUMAN
θ value	0.00134147 (rank : 42)	NC score	0.248995 (rank : 36)
Query Neighborhood Hits	351	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

PHF1_MOUSE
θ value	0.00134147 (rank : 43)	NC score	0.036114 (rank : 117)
Query Neighborhood Hits	351	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

KCND1_HUMAN
θ value	0.00298849 (rank : 44)	NC score	0.178959 (rank : 49)
Query Neighborhood Hits	351	Target Neighborhood Hits	160	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

SPTN4_HUMAN
θ value	0.00509761 (rank : 45)	NC score	0.019109 (rank : 185)
Query Neighborhood Hits	351	Target Neighborhood Hits	570	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

TRHY_HUMAN
θ value	0.00665767 (rank : 46)	NC score	0.021243 (rank : 170)
Query Neighborhood Hits	351	Target Neighborhood Hits	1385	Shared Neighborhood Hits	50
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRPM8_MOUSE
θ value	0.0113563 (rank : 47)	NC score	0.069565 (rank : 84)
Query Neighborhood Hits	351	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

KCNA6_MOUSE
θ value	0.0148317 (rank : 48)	NC score	0.100880 (rank : 63)
Query Neighborhood Hits	351	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNB2_HUMAN
θ value	0.0148317 (rank : 49)	NC score	0.218013 (rank : 38)
Query Neighborhood Hits	351	Target Neighborhood Hits	212	Shared Neighborhood Hits	71
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNC1_HUMAN
θ value	0.0148317 (rank : 50)	NC score	0.150218 (rank : 51)
Query Neighborhood Hits	351	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

NPBL_MOUSE
θ value	0.0148317 (rank : 51)	NC score	0.068189 (rank : 86)
Query Neighborhood Hits	351	Target Neighborhood Hits	1041	Shared Neighborhood Hits	83
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TRPM8_HUMAN
θ value	0.0148317 (rank : 52)	NC score	0.064623 (rank : 89)
Query Neighborhood Hits	351	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

GSCR1_HUMAN
θ value	0.0193708 (rank : 53)	NC score	0.042894 (rank : 110)
Query Neighborhood Hits	351	Target Neighborhood Hits	674	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KCNC1_MOUSE
θ value	0.0193708 (rank : 54)	NC score	0.148311 (rank : 52)
Query Neighborhood Hits	351	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

OXR1_MOUSE
θ value	0.0193708 (rank : 55)	NC score	0.031847 (rank : 128)
Query Neighborhood Hits	351	Target Neighborhood Hits	516	Shared Neighborhood Hits	43
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

RFIP5_MOUSE
θ value	0.0193708 (rank : 56)	NC score	0.040841 (rank : 111)
Query Neighborhood Hits	351	Target Neighborhood Hits	126	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

WNK4_MOUSE
θ value	0.0193708 (rank : 57)	NC score	0.003846 (rank : 329)
Query Neighborhood Hits	351	Target Neighborhood Hits	961	Shared Neighborhood Hits	36
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ARI1A_HUMAN
θ value	0.0252991 (rank : 58)	NC score	0.038910 (rank : 112)
Query Neighborhood Hits	351	Target Neighborhood Hits	787	Shared Neighborhood Hits	85
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

KCNA1_MOUSE
θ value	0.0252991 (rank : 59)	NC score	0.106148 (rank : 61)
Query Neighborhood Hits	351	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNS2_MOUSE
θ value	0.0252991 (rank : 60)	NC score	0.214166 (rank : 39)
Query Neighborhood Hits	351	Target Neighborhood Hits	130	Shared Neighborhood Hits	62
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

PTPRN_MOUSE
θ value	0.0252991 (rank : 61)	NC score	0.013815 (rank : 216)
Query Neighborhood Hits	351	Target Neighborhood Hits	240	Shared Neighborhood Hits	23
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

TRPC4_MOUSE
θ value	0.0252991 (rank : 62)	NC score	0.050222 (rank : 98)
Query Neighborhood Hits	351	Target Neighborhood Hits	141	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

KCNS2_HUMAN
θ value	0.0330416 (rank : 63)	NC score	0.210092 (rank : 40)
Query Neighborhood Hits	351	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

TRPC4_HUMAN
θ value	0.0330416 (rank : 64)	NC score	0.051947 (rank : 97)
Query Neighborhood Hits	351	Target Neighborhood Hits	140	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

CCD55_MOUSE
θ value	0.0431538 (rank : 65)	NC score	0.044950 (rank : 106)
Query Neighborhood Hits	351	Target Neighborhood Hits	519	Shared Neighborhood Hits	33
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CD248_HUMAN
θ value	0.0431538 (rank : 66)	NC score	0.021753 (rank : 166)
Query Neighborhood Hits	351	Target Neighborhood Hits	679	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KCNA1_HUMAN
θ value	0.0431538 (rank : 67)	NC score	0.104223 (rank : 62)
Query Neighborhood Hits	351	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNB1_HUMAN
θ value	0.0431538 (rank : 68)	NC score	0.203883 (rank : 42)
Query Neighborhood Hits	351	Target Neighborhood Hits	169	Shared Neighborhood Hits	65
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0.0431538 (rank : 69)	NC score	0.203944 (rank : 41)
Query Neighborhood Hits	351	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

FILA_HUMAN
θ value	0.0563607 (rank : 70)	NC score	0.044774 (rank : 108)
Query Neighborhood Hits	351	Target Neighborhood Hits	685	Shared Neighborhood Hits	55
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

SETBP_MOUSE
θ value	0.0563607 (rank : 71)	NC score	0.028317 (rank : 137)
Query Neighborhood Hits	351	Target Neighborhood Hits	352	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

TREF1_HUMAN
θ value	0.0563607 (rank : 72)	NC score	0.028172 (rank : 139)
Query Neighborhood Hits	351	Target Neighborhood Hits	651	Shared Neighborhood Hits	28
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

SFRIP_HUMAN
θ value	0.0736092 (rank : 73)	NC score	0.035156 (rank : 122)
Query Neighborhood Hits	351	Target Neighborhood Hits	530	Shared Neighborhood Hits	55
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

MCLN2_HUMAN
θ value	0.0961366 (rank : 74)	NC score	0.069372 (rank : 85)
Query Neighborhood Hits	351	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MLL2_HUMAN
θ value	0.0961366 (rank : 75)	NC score	0.032146 (rank : 127)
Query Neighborhood Hits	351	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ZN516_MOUSE
θ value	0.0961366 (rank : 76)	NC score	0.005365 (rank : 309)
Query Neighborhood Hits	351	Target Neighborhood Hits	1197	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CEND1_HUMAN
θ value	0.125558 (rank : 77)	NC score	0.012735 (rank : 227)
Query Neighborhood Hits	351	Target Neighborhood Hits	284	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

KCNA6_HUMAN
θ value	0.125558 (rank : 78)	NC score	0.094518 (rank : 66)
Query Neighborhood Hits	351	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KTNA1_HUMAN
θ value	0.125558 (rank : 79)	NC score	0.010860 (rank : 249)
Query Neighborhood Hits	351	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

DACT1_HUMAN
θ value	0.163984 (rank : 80)	NC score	0.043657 (rank : 109)
Query Neighborhood Hits	351	Target Neighborhood Hits	228	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

KCNC4_MOUSE
θ value	0.163984 (rank : 81)	NC score	0.136948 (rank : 55)
Query Neighborhood Hits	351	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG3_HUMAN
θ value	0.163984 (rank : 82)	NC score	0.124219 (rank : 58)
Query Neighborhood Hits	351	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

MCLN2_MOUSE
θ value	0.163984 (rank : 83)	NC score	0.094414 (rank : 67)
Query Neighborhood Hits	351	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

NIPBL_HUMAN
θ value	0.163984 (rank : 84)	NC score	0.057702 (rank : 94)
Query Neighborhood Hits	351	Target Neighborhood Hits	1311	Shared Neighborhood Hits	96
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SNIP1_MOUSE
θ value	0.163984 (rank : 85)	NC score	0.030113 (rank : 130)
Query Neighborhood Hits	351	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

ATX1_MOUSE
θ value	0.21417 (rank : 86)	NC score	0.028010 (rank : 140)
Query Neighborhood Hits	351	Target Neighborhood Hits	264	Shared Neighborhood Hits	32
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

KCNC4_HUMAN
θ value	0.21417 (rank : 87)	NC score	0.144426 (rank : 53)
Query Neighborhood Hits	351	Target Neighborhood Hits	141	Shared Neighborhood Hits	58
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNS3_HUMAN
θ value	0.21417 (rank : 88)	NC score	0.182501 (rank : 48)
Query Neighborhood Hits	351	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

RB15B_MOUSE
θ value	0.21417 (rank : 89)	NC score	0.020250 (rank : 179)
Query Neighborhood Hits	351	Target Neighborhood Hits	284	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

RENT1_MOUSE
θ value	0.21417 (rank : 90)	NC score	0.028629 (rank : 135)
Query Neighborhood Hits	351	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

TAF4_HUMAN
θ value	0.21417 (rank : 91)	NC score	0.046551 (rank : 101)
Query Neighborhood Hits	351	Target Neighborhood Hits	687	Shared Neighborhood Hits	83
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_HUMAN
θ value	0.21417 (rank : 92)	NC score	0.049149 (rank : 100)
Query Neighborhood Hits	351	Target Neighborhood Hits	1626	Shared Neighborhood Hits	129
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ACK1_MOUSE
θ value	0.279714 (rank : 93)	NC score	0.003097 (rank : 333)
Query Neighborhood Hits	351	Target Neighborhood Hits	1080	Shared Neighborhood Hits	60
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

CAP1_HUMAN
θ value	0.279714 (rank : 94)	NC score	0.024739 (rank : 150)
Query Neighborhood Hits	351	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q01518, Q53HR7, Q5T0S1, Q6I9U6	Gene names	CAP1, CAP
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CSKI2_MOUSE
θ value	0.279714 (rank : 95)	NC score	0.010782 (rank : 250)
Query Neighborhood Hits	351	Target Neighborhood Hits	812	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

RENT1_HUMAN
θ value	0.279714 (rank : 96)	NC score	0.028271 (rank : 138)
Query Neighborhood Hits	351	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

SMOO_HUMAN
θ value	0.279714 (rank : 97)	NC score	0.030044 (rank : 131)
Query Neighborhood Hits	351	Target Neighborhood Hits	391	Shared Neighborhood Hits	45
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

ARI3A_MOUSE
θ value	0.365318 (rank : 98)	NC score	0.025274 (rank : 146)
Query Neighborhood Hits	351	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q62431	Gene names	Arid3a, Dri1, Dril1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (Dead ringer-like protein 1) (B-cell regulator of IgH transcription) (Bright).

PELP1_MOUSE
θ value	0.365318 (rank : 99)	NC score	0.021226 (rank : 171)
Query Neighborhood Hits	351	Target Neighborhood Hits	709	Shared Neighborhood Hits	68
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RGS3_MOUSE
θ value	0.365318 (rank : 100)	NC score	0.037895 (rank : 114)
Query Neighborhood Hits	351	Target Neighborhood Hits	1621	Shared Neighborhood Hits	153
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RNF12_MOUSE
θ value	0.365318 (rank : 101)	NC score	0.016026 (rank : 205)
Query Neighborhood Hits	351	Target Neighborhood Hits	159	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

SRRM1_MOUSE
θ value	0.365318 (rank : 102)	NC score	0.058440 (rank : 93)
Query Neighborhood Hits	351	Target Neighborhood Hits	966	Shared Neighborhood Hits	118
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TOIP2_MOUSE
θ value	0.365318 (rank : 103)	NC score	0.025765 (rank : 144)
Query Neighborhood Hits	351	Target Neighborhood Hits	115	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

DGKK_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.016228 (rank : 203)
Query Neighborhood Hits	351	Target Neighborhood Hits	378	Shared Neighborhood Hits	38
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

KCNQ1_MOUSE
θ value	0.47712 (rank : 105)	NC score	0.086397 (rank : 71)
Query Neighborhood Hits	351	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KTNA1_MOUSE
θ value	0.47712 (rank : 106)	NC score	0.009474 (rank : 265)
Query Neighborhood Hits	351	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

NACAM_MOUSE
θ value	0.47712 (rank : 107)	NC score	0.037510 (rank : 116)
Query Neighborhood Hits	351	Target Neighborhood Hits	1866	Shared Neighborhood Hits	156
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PHLA1_HUMAN
θ value	0.47712 (rank : 108)	NC score	0.020766 (rank : 173)
Query Neighborhood Hits	351	Target Neighborhood Hits	121	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

PININ_HUMAN
θ value	0.47712 (rank : 109)	NC score	0.028634 (rank : 134)
Query Neighborhood Hits	351	Target Neighborhood Hits	753	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PO6F2_HUMAN
θ value	0.47712 (rank : 110)	NC score	0.016798 (rank : 199)
Query Neighborhood Hits	351	Target Neighborhood Hits	618	Shared Neighborhood Hits	46
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PTN23_MOUSE
θ value	0.47712 (rank : 111)	NC score	0.013562 (rank : 219)
Query Neighborhood Hits	351	Target Neighborhood Hits	726	Shared Neighborhood Hits	69
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SPEG_HUMAN
θ value	0.47712 (rank : 112)	NC score	0.005612 (rank : 304)
Query Neighborhood Hits	351	Target Neighborhood Hits	1762	Shared Neighborhood Hits	95
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SREC2_HUMAN
θ value	0.47712 (rank : 113)	NC score	0.009191 (rank : 268)
Query Neighborhood Hits	351	Target Neighborhood Hits	645	Shared Neighborhood Hits	44
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SYP2L_HUMAN
θ value	0.47712 (rank : 114)	NC score	0.024088 (rank : 152)
Query Neighborhood Hits	351	Target Neighborhood Hits	400	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

YLPM1_HUMAN
θ value	0.47712 (rank : 115)	NC score	0.035385 (rank : 121)
Query Neighborhood Hits	351	Target Neighborhood Hits	670	Shared Neighborhood Hits	74
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

BSN_HUMAN
θ value	0.62314 (rank : 116)	NC score	0.037677 (rank : 115)
Query Neighborhood Hits	351	Target Neighborhood Hits	1537	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

HCN4_MOUSE
θ value	0.62314 (rank : 117)	NC score	0.018406 (rank : 190)
Query Neighborhood Hits	351	Target Neighborhood Hits	284	Shared Neighborhood Hits	47
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

KCNG3_MOUSE
θ value	0.62314 (rank : 118)	NC score	0.120872 (rank : 60)
Query Neighborhood Hits	351	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNS1_HUMAN
θ value	0.62314 (rank : 119)	NC score	0.158272 (rank : 50)
Query Neighborhood Hits	351	Target Neighborhood Hits	116	Shared Neighborhood Hits	60
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

MEFV_HUMAN
θ value	0.62314 (rank : 120)	NC score	0.007620 (rank : 281)
Query Neighborhood Hits	351	Target Neighborhood Hits	431	Shared Neighborhood Hits	30
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

NFAC3_MOUSE
θ value	0.62314 (rank : 121)	NC score	0.012699 (rank : 228)
Query Neighborhood Hits	351	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

PAXI_MOUSE
θ value	0.62314 (rank : 122)	NC score	0.004685 (rank : 321)
Query Neighborhood Hits	351	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

SRRM1_HUMAN
θ value	0.62314 (rank : 123)	NC score	0.049158 (rank : 99)
Query Neighborhood Hits	351	Target Neighborhood Hits	690	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TAU_MOUSE
θ value	0.62314 (rank : 124)	NC score	0.029843 (rank : 132)
Query Neighborhood Hits	351	Target Neighborhood Hits	502	Shared Neighborhood Hits	75
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TTC16_HUMAN
θ value	0.62314 (rank : 125)	NC score	0.033499 (rank : 124)
Query Neighborhood Hits	351	Target Neighborhood Hits	417	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

CIC_HUMAN
θ value	0.813845 (rank : 126)	NC score	0.024347 (rank : 151)
Query Neighborhood Hits	351	Target Neighborhood Hits	992	Shared Neighborhood Hits	106
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	0.813845 (rank : 127)	NC score	0.023671 (rank : 155)
Query Neighborhood Hits	351	Target Neighborhood Hits	742	Shared Neighborhood Hits	85
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

GLU2B_MOUSE
θ value	0.813845 (rank : 128)	NC score	0.016202 (rank : 204)
Query Neighborhood Hits	351	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

MBD5_HUMAN
θ value	0.813845 (rank : 129)	NC score	0.033101 (rank : 125)
Query Neighborhood Hits	351	Target Neighborhood Hits	176	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MCLN1_MOUSE
θ value	0.813845 (rank : 130)	NC score	0.045788 (rank : 103)
Query Neighborhood Hits	351	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q99J21	Gene names	Mcoln1
Domain Architecture	No domain graphic available
Description	Mucolipin-1 (Mucolipidin).

MEF2B_MOUSE
θ value	0.813845 (rank : 131)	NC score	0.016328 (rank : 201)
Query Neighborhood Hits	351	Target Neighborhood Hits	218	Shared Neighborhood Hits	30
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

PPAC2_MOUSE
θ value	0.813845 (rank : 132)	NC score	0.024065 (rank : 153)
Query Neighborhood Hits	351	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4F2	Gene names	Ppapdc2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

EMIL2_MOUSE
θ value	1.06291 (rank : 133)	NC score	0.008096 (rank : 273)
Query Neighborhood Hits	351	Target Neighborhood Hits	485	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

HCN4_HUMAN
θ value	1.06291 (rank : 134)	NC score	0.018816 (rank : 188)
Query Neighborhood Hits	351	Target Neighborhood Hits	303	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

JIP2_MOUSE
θ value	1.06291 (rank : 135)	NC score	0.020630 (rank : 175)
Query Neighborhood Hits	351	Target Neighborhood Hits	144	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

MCLN3_MOUSE
θ value	1.06291 (rank : 136)	NC score	0.058651 (rank : 92)
Query Neighborhood Hits	351	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4F0, Q8BS73, Q8BSG1, Q8CDB2	Gene names	Mcoln3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

MPP8_HUMAN
θ value	1.06291 (rank : 137)	NC score	0.007598 (rank : 282)
Query Neighborhood Hits	351	Target Neighborhood Hits	948	Shared Neighborhood Hits	40
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NRG3_HUMAN
θ value	1.06291 (rank : 138)	NC score	0.016326 (rank : 202)
Query Neighborhood Hits	351	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

PAK4_MOUSE
θ value	1.06291 (rank : 139)	NC score	0.001571 (rank : 342)
Query Neighborhood Hits	351	Target Neighborhood Hits	1098	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

RADI_HUMAN
θ value	1.06291 (rank : 140)	NC score	0.007968 (rank : 276)
Query Neighborhood Hits	351	Target Neighborhood Hits	741	Shared Neighborhood Hits	30
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	1.06291 (rank : 141)	NC score	0.007960 (rank : 278)
Query Neighborhood Hits	351	Target Neighborhood Hits	773	Shared Neighborhood Hits	29
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

SYP2L_MOUSE
θ value	1.06291 (rank : 142)	NC score	0.021904 (rank : 164)
Query Neighborhood Hits	351	Target Neighborhood Hits	289	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ANK2_HUMAN
θ value	1.38821 (rank : 143)	NC score	0.017205 (rank : 196)
Query Neighborhood Hits	351	Target Neighborhood Hits	1615	Shared Neighborhood Hits	132
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASTL_HUMAN
θ value	1.38821 (rank : 144)	NC score	0.023661 (rank : 156)
Query Neighborhood Hits	351	Target Neighborhood Hits	252	Shared Neighborhood Hits	40
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ATX7_MOUSE
θ value	1.38821 (rank : 145)	NC score	0.029428 (rank : 133)
Query Neighborhood Hits	351	Target Neighborhood Hits	328	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BIM_MOUSE
θ value	1.38821 (rank : 146)	NC score	0.038688 (rank : 113)
Query Neighborhood Hits	351	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	O54918, O54919, O54920	Gene names	Bcl2l11, Bim
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

LUZP1_MOUSE
θ value	1.38821 (rank : 147)	NC score	0.007937 (rank : 279)
Query Neighborhood Hits	351	Target Neighborhood Hits	940	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

M3K12_MOUSE
θ value	1.38821 (rank : 148)	NC score	-0.001562 (rank : 360)
Query Neighborhood Hits	351	Target Neighborhood Hits	957	Shared Neighborhood Hits	32
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MAP4_MOUSE
θ value	1.38821 (rank : 149)	NC score	0.027489 (rank : 141)
Query Neighborhood Hits	351	Target Neighborhood Hits	409	Shared Neighborhood Hits	55
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NR1H3_MOUSE
θ value	1.38821 (rank : 150)	NC score	0.001539 (rank : 344)
Query Neighborhood Hits	351	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

PCGF2_HUMAN
θ value	1.38821 (rank : 151)	NC score	0.009460 (rank : 266)
Query Neighborhood Hits	351	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PLXB1_HUMAN
θ value	1.38821 (rank : 152)	NC score	0.008352 (rank : 270)
Query Neighborhood Hits	351	Target Neighborhood Hits	360	Shared Neighborhood Hits	41
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

ROAA_MOUSE
θ value	1.38821 (rank : 153)	NC score	0.004975 (rank : 316)
Query Neighborhood Hits	351	Target Neighborhood Hits	208	Shared Neighborhood Hits	9
SwissProt Accessions	Q99020, Q8BPE0	Gene names	Hnrpab, Cbf-a, Cgbfa
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A).

SF3B4_HUMAN
θ value	1.38821 (rank : 154)	NC score	0.022711 (rank : 159)
Query Neighborhood Hits	351	Target Neighborhood Hits	445	Shared Neighborhood Hits	45
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

T22D2_HUMAN
θ value	1.38821 (rank : 155)	NC score	0.019347 (rank : 183)
Query Neighborhood Hits	351	Target Neighborhood Hits	250	Shared Neighborhood Hits	29
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TRPS1_HUMAN
θ value	1.38821 (rank : 156)	NC score	0.009632 (rank : 262)
Query Neighborhood Hits	351	Target Neighborhood Hits	539	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

TTC14_HUMAN
θ value	1.38821 (rank : 157)	NC score	0.016441 (rank : 200)
Query Neighborhood Hits	351	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

ANKZ1_MOUSE
θ value	1.81305 (rank : 158)	NC score	0.012247 (rank : 232)
Query Neighborhood Hits	351	Target Neighborhood Hits	208	Shared Neighborhood Hits	13
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ATX7_HUMAN
θ value	1.81305 (rank : 159)	NC score	0.035681 (rank : 119)
Query Neighborhood Hits	351	Target Neighborhood Hits	351	Shared Neighborhood Hits	58
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CAP1_MOUSE
θ value	1.81305 (rank : 160)	NC score	0.017124 (rank : 198)
Query Neighborhood Hits	351	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CENG1_MOUSE
θ value	1.81305 (rank : 161)	NC score	0.010755 (rank : 251)
Query Neighborhood Hits	351	Target Neighborhood Hits	531	Shared Neighborhood Hits	32
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CS029_HUMAN
θ value	1.81305 (rank : 162)	NC score	0.013229 (rank : 223)
Query Neighborhood Hits	351	Target Neighborhood Hits	329	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

CTRO_HUMAN
θ value	1.81305 (rank : 163)	NC score	-0.000281 (rank : 355)
Query Neighborhood Hits	351	Target Neighborhood Hits	2092	Shared Neighborhood Hits	67
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DYN1_HUMAN
θ value	1.81305 (rank : 164)	NC score	0.015525 (rank : 209)
Query Neighborhood Hits	351	Target Neighborhood Hits	216	Shared Neighborhood Hits	37
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

JPH2_HUMAN
θ value	1.81305 (rank : 165)	NC score	0.025149 (rank : 147)
Query Neighborhood Hits	351	Target Neighborhood Hits	639	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

M3K6_HUMAN
θ value	1.81305 (rank : 166)	NC score	-0.001152 (rank : 359)
Query Neighborhood Hits	351	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MTF1_MOUSE
θ value	1.81305 (rank : 167)	NC score	-0.003572 (rank : 367)
Query Neighborhood Hits	351	Target Neighborhood Hits	785	Shared Neighborhood Hits	24
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NOTC3_MOUSE
θ value	1.81305 (rank : 168)	NC score	0.000211 (rank : 350)
Query Neighborhood Hits	351	Target Neighborhood Hits	975	Shared Neighborhood Hits	32
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PAX9_HUMAN
θ value	1.81305 (rank : 169)	NC score	0.014050 (rank : 215)
Query Neighborhood Hits	351	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

PIM2_MOUSE
θ value	1.81305 (rank : 170)	NC score	-0.001833 (rank : 364)
Query Neighborhood Hits	351	Target Neighborhood Hits	809	Shared Neighborhood Hits	17
SwissProt Accessions	Q62070, Q62071, Q62072	Gene names	Pim2, Pim-2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1).

SOCS7_MOUSE
θ value	1.81305 (rank : 171)	NC score	0.010937 (rank : 247)
Query Neighborhood Hits	351	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SSH1_MOUSE
θ value	1.81305 (rank : 172)	NC score	0.005561 (rank : 306)
Query Neighborhood Hits	351	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

TARA_MOUSE
θ value	1.81305 (rank : 173)	NC score	0.035753 (rank : 118)
Query Neighborhood Hits	351	Target Neighborhood Hits	1133	Shared Neighborhood Hits	99
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TREF1_MOUSE
θ value	1.81305 (rank : 174)	NC score	0.019632 (rank : 181)
Query Neighborhood Hits	351	Target Neighborhood Hits	682	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

A16L1_HUMAN
θ value	2.36792 (rank : 175)	NC score	0.007974 (rank : 275)
Query Neighborhood Hits	351	Target Neighborhood Hits	664	Shared Neighborhood Hits	27
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

ABL2_HUMAN
θ value	2.36792 (rank : 176)	NC score	-0.002141 (rank : 365)
Query Neighborhood Hits	351	Target Neighborhood Hits	1045	Shared Neighborhood Hits	30
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

BAP1_HUMAN
θ value	2.36792 (rank : 177)	NC score	0.017129 (rank : 197)
Query Neighborhood Hits	351	Target Neighborhood Hits	106	Shared Neighborhood Hits	18
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

CENG1_HUMAN
θ value	2.36792 (rank : 178)	NC score	0.012976 (rank : 224)
Query Neighborhood Hits	351	Target Neighborhood Hits	544	Shared Neighborhood Hits	32
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

IRS2_MOUSE
θ value	2.36792 (rank : 179)	NC score	0.019057 (rank : 187)
Query Neighborhood Hits	351	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

K0460_HUMAN
θ value	2.36792 (rank : 180)	NC score	0.012374 (rank : 231)
Query Neighborhood Hits	351	Target Neighborhood Hits	357	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K1849_HUMAN
θ value	2.36792 (rank : 181)	NC score	0.006458 (rank : 298)
Query Neighborhood Hits	351	Target Neighborhood Hits	220	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LTBP4_MOUSE
θ value	2.36792 (rank : 182)	NC score	0.001796 (rank : 341)
Query Neighborhood Hits	351	Target Neighborhood Hits	607	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MAST4_HUMAN
θ value	2.36792 (rank : 183)	NC score	0.005199 (rank : 313)
Query Neighborhood Hits	351	Target Neighborhood Hits	1804	Shared Neighborhood Hits	113
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MCLN3_HUMAN
θ value	2.36792 (rank : 184)	NC score	0.053485 (rank : 96)
Query Neighborhood Hits	351	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDD5, Q5T4H5, Q5T4H6, Q9NV09	Gene names	MCOLN3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

MEA1_MOUSE
θ value	2.36792 (rank : 185)	NC score	0.020329 (rank : 177)
Query Neighborhood Hits	351	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q64327	Gene names	Mea1, Mea
Domain Architecture
Description	Male-enhanced antigen 1 (MEA-1).

NU133_HUMAN
θ value	2.36792 (rank : 186)	NC score	0.011279 (rank : 241)
Query Neighborhood Hits	351	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

PEG3_MOUSE
θ value	2.36792 (rank : 187)	NC score	-0.000228 (rank : 354)
Query Neighborhood Hits	351	Target Neighborhood Hits	1101	Shared Neighborhood Hits	38
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PO121_HUMAN
θ value	2.36792 (rank : 188)	NC score	0.015207 (rank : 210)
Query Neighborhood Hits	351	Target Neighborhood Hits	344	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RRBP1_MOUSE
θ value	2.36792 (rank : 189)	NC score	0.011988 (rank : 235)
Query Neighborhood Hits	351	Target Neighborhood Hits	1650	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SALL3_HUMAN
θ value	2.36792 (rank : 190)	NC score	0.000012 (rank : 352)
Query Neighborhood Hits	351	Target Neighborhood Hits	1066	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SDPR_MOUSE
θ value	2.36792 (rank : 191)	NC score	0.014269 (rank : 214)
Query Neighborhood Hits	351	Target Neighborhood Hits	485	Shared Neighborhood Hits	24
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SET1A_HUMAN
θ value	2.36792 (rank : 192)	NC score	0.020381 (rank : 176)
Query Neighborhood Hits	351	Target Neighborhood Hits	690	Shared Neighborhood Hits	61
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SYN1_HUMAN
θ value	2.36792 (rank : 193)	NC score	0.035404 (rank : 120)
Query Neighborhood Hits	351	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN3_HUMAN
θ value	2.36792 (rank : 194)	NC score	0.027199 (rank : 142)
Query Neighborhood Hits	351	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TMPSD_MOUSE
θ value	2.36792 (rank : 195)	NC score	0.000086 (rank : 351)
Query Neighborhood Hits	351	Target Neighborhood Hits	334	Shared Neighborhood Hits	26
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ZIM10_HUMAN
θ value	2.36792 (rank : 196)	NC score	0.012596 (rank : 229)
Query Neighborhood Hits	351	Target Neighborhood Hits	577	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN750_MOUSE
θ value	2.36792 (rank : 197)	NC score	0.022084 (rank : 162)
Query Neighborhood Hits	351	Target Neighborhood Hits	346	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

A16L1_MOUSE
θ value	3.0926 (rank : 198)	NC score	0.009797 (rank : 260)
Query Neighborhood Hits	351	Target Neighborhood Hits	776	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

ARI3A_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.021390 (rank : 169)
Query Neighborhood Hits	351	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

CCD1A_HUMAN
θ value	3.0926 (rank : 200)	NC score	0.012159 (rank : 233)
Query Neighborhood Hits	351	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

GATA6_HUMAN
θ value	3.0926 (rank : 201)	NC score	0.007206 (rank : 286)
Query Neighborhood Hits	351	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	Q92908, P78327	Gene names	GATA6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

GBF1_HUMAN
θ value	3.0926 (rank : 202)	NC score	0.008006 (rank : 274)
Query Neighborhood Hits	351	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

GIT2_MOUSE
θ value	3.0926 (rank : 203)	NC score	0.007578 (rank : 283)
Query Neighborhood Hits	351	Target Neighborhood Hits	323	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

ITSN1_HUMAN
θ value	3.0926 (rank : 204)	NC score	0.004176 (rank : 325)
Query Neighborhood Hits	351	Target Neighborhood Hits	1757	Shared Neighborhood Hits	83
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KCNA5_HUMAN
θ value	3.0926 (rank : 205)	NC score	0.083893 (rank : 76)
Query Neighborhood Hits	351	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	3.0926 (rank : 206)	NC score	0.089705 (rank : 70)
Query Neighborhood Hits	351	Target Neighborhood Hits	119	Shared Neighborhood Hits	43
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

MCLN1_HUMAN
θ value	3.0926 (rank : 207)	NC score	0.044780 (rank : 107)
Query Neighborhood Hits	351	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZU1, Q7Z4F7, Q9H292, Q9H4B3, Q9H4B5	Gene names	MCOLN1, ML4
Domain Architecture	No domain graphic available
Description	Mucolipin-1 (Mucolipidin) (MG-2).

MEA1_HUMAN
θ value	3.0926 (rank : 208)	NC score	0.019102 (rank : 186)
Query Neighborhood Hits	351	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q16626, Q5TC36, Q9BV01	Gene names	MEA1, MEA
Domain Architecture
Description	Male-enhanced antigen 1 (MEA-1).

MINT_MOUSE
θ value	3.0926 (rank : 209)	NC score	0.032365 (rank : 126)
Query Neighborhood Hits	351	Target Neighborhood Hits	1514	Shared Neighborhood Hits	123
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NEIL1_MOUSE
θ value	3.0926 (rank : 210)	NC score	0.011175 (rank : 243)
Query Neighborhood Hits	351	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

PRG4_HUMAN
θ value	3.0926 (rank : 211)	NC score	0.019488 (rank : 182)
Query Neighborhood Hits	351	Target Neighborhood Hits	764	Shared Neighborhood Hits	65
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SGIP1_MOUSE
θ value	3.0926 (rank : 212)	NC score	0.026819 (rank : 143)
Query Neighborhood Hits	351	Target Neighborhood Hits	180	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SNPC4_HUMAN
θ value	3.0926 (rank : 213)	NC score	0.025368 (rank : 145)
Query Neighborhood Hits	351	Target Neighborhood Hits	589	Shared Neighborhood Hits	78
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SOX9_MOUSE
θ value	3.0926 (rank : 214)	NC score	0.006291 (rank : 300)
Query Neighborhood Hits	351	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SPESP_MOUSE
θ value	3.0926 (rank : 215)	NC score	0.013303 (rank : 220)
Query Neighborhood Hits	351	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

SPHK2_MOUSE
θ value	3.0926 (rank : 216)	NC score	0.012850 (rank : 226)
Query Neighborhood Hits	351	Target Neighborhood Hits	78	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

ZC3H3_MOUSE
θ value	3.0926 (rank : 217)	NC score	0.012474 (rank : 230)
Query Neighborhood Hits	351	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZEP1_MOUSE
θ value	3.0926 (rank : 218)	NC score	0.001554 (rank : 343)
Query Neighborhood Hits	351	Target Neighborhood Hits	1063	Shared Neighborhood Hits	58
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

B4GT1_HUMAN
θ value	4.03905 (rank : 219)	NC score	0.005944 (rank : 302)
Query Neighborhood Hits	351	Target Neighborhood Hits	168	Shared Neighborhood Hits	23
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

BRD2_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.010969 (rank : 246)
Query Neighborhood Hits	351	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BSN_MOUSE
θ value	4.03905 (rank : 221)	NC score	0.045299 (rank : 105)
Query Neighborhood Hits	351	Target Neighborhood Hits	2057	Shared Neighborhood Hits	171
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD55_HUMAN
θ value	4.03905 (rank : 222)	NC score	0.033784 (rank : 123)
Query Neighborhood Hits	351	Target Neighborhood Hits	513	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CO2A1_HUMAN
θ value	4.03905 (rank : 223)	NC score	0.013772 (rank : 218)
Query Neighborhood Hits	351	Target Neighborhood Hits	486	Shared Neighborhood Hits	51
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

DJBP_MOUSE
θ value	4.03905 (rank : 224)	NC score	0.045510 (rank : 104)
Query Neighborhood Hits	351	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

ERF_HUMAN
θ value	4.03905 (rank : 225)	NC score	0.006927 (rank : 291)
Query Neighborhood Hits	351	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
θ value	4.03905 (rank : 226)	NC score	0.006772 (rank : 295)
Query Neighborhood Hits	351	Target Neighborhood Hits	160	Shared Neighborhood Hits	21
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

GP160_HUMAN
θ value	4.03905 (rank : 227)	NC score	0.014418 (rank : 213)
Query Neighborhood Hits	351	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ42	Gene names	GPR160, GPCR150
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 160.

HXB4_MOUSE
θ value	4.03905 (rank : 228)	NC score	-0.001017 (rank : 358)
Query Neighborhood Hits	351	Target Neighborhood Hits	375	Shared Neighborhood Hits	12
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

ITSN2_MOUSE
θ value	4.03905 (rank : 229)	NC score	0.002586 (rank : 336)
Query Neighborhood Hits	351	Target Neighborhood Hits	1371	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

K1024_MOUSE
θ value	4.03905 (rank : 230)	NC score	0.007963 (rank : 277)
Query Neighborhood Hits	351	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3V7, Q69ZS9	Gene names	Kiaa1024
Domain Architecture
Description	UPF0258 protein KIAA1024 (Protein DD1).

KCNQ3_HUMAN
θ value	4.03905 (rank : 231)	NC score	0.067413 (rank : 87)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	41
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	4.03905 (rank : 232)	NC score	0.066059 (rank : 88)
Query Neighborhood Hits	351	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KLF14_HUMAN
θ value	4.03905 (rank : 233)	NC score	-0.003617 (rank : 368)
Query Neighborhood Hits	351	Target Neighborhood Hits	725	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

M3K1_MOUSE
θ value	4.03905 (rank : 234)	NC score	-0.000513 (rank : 356)
Query Neighborhood Hits	351	Target Neighborhood Hits	952	Shared Neighborhood Hits	31
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MUC2_HUMAN
θ value	4.03905 (rank : 235)	NC score	0.010368 (rank : 254)
Query Neighborhood Hits	351	Target Neighborhood Hits	906	Shared Neighborhood Hits	63
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MYH4_HUMAN
θ value	4.03905 (rank : 236)	NC score	0.000366 (rank : 348)
Query Neighborhood Hits	351	Target Neighborhood Hits	1377	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

NKX24_MOUSE
θ value	4.03905 (rank : 237)	NC score	0.003395 (rank : 332)
Query Neighborhood Hits	351	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EQM3, Q9EQM4	Gene names	Nkx2-4, Nkx2d
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

PHLB1_HUMAN
θ value	4.03905 (rank : 238)	NC score	0.021751 (rank : 167)
Query Neighborhood Hits	351	Target Neighborhood Hits	1038	Shared Neighborhood Hits	80
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RIMB1_MOUSE
θ value	4.03905 (rank : 239)	NC score	0.006605 (rank : 296)
Query Neighborhood Hits	351	Target Neighborhood Hits	1376	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SOX7_HUMAN
θ value	4.03905 (rank : 240)	NC score	0.005143 (rank : 314)
Query Neighborhood Hits	351	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SSBP3_HUMAN
θ value	4.03905 (rank : 241)	NC score	0.013287 (rank : 221)
Query Neighborhood Hits	351	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	4.03905 (rank : 242)	NC score	0.013287 (rank : 222)
Query Neighborhood Hits	351	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

TDRD3_HUMAN
θ value	4.03905 (rank : 243)	NC score	0.010457 (rank : 253)
Query Neighborhood Hits	351	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

TRPM7_MOUSE
θ value	4.03905 (rank : 244)	NC score	0.020051 (rank : 180)
Query Neighborhood Hits	351	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

UBE4B_HUMAN
θ value	4.03905 (rank : 245)	NC score	0.015960 (rank : 207)
Query Neighborhood Hits	351	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ZO1_HUMAN
θ value	4.03905 (rank : 246)	NC score	0.006814 (rank : 294)
Query Neighborhood Hits	351	Target Neighborhood Hits	474	Shared Neighborhood Hits	35
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CABIN_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.022889 (rank : 158)
Query Neighborhood Hits	351	Target Neighborhood Hits	490	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CBP_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.022596 (rank : 160)
Query Neighborhood Hits	351	Target Neighborhood Hits	941	Shared Neighborhood Hits	100
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CO4A4_HUMAN
θ value	5.27518 (rank : 249)	NC score	0.012088 (rank : 234)
Query Neighborhood Hits	351	Target Neighborhood Hits	440	Shared Neighborhood Hits	47
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CSKI1_MOUSE
θ value	5.27518 (rank : 250)	NC score	0.010287 (rank : 255)
Query Neighborhood Hits	351	Target Neighborhood Hits	1031	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EPN2_MOUSE
θ value	5.27518 (rank : 251)	NC score	0.006861 (rank : 293)
Query Neighborhood Hits	351	Target Neighborhood Hits	111	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

FOG1_MOUSE
θ value	5.27518 (rank : 252)	NC score	0.010735 (rank : 252)
Query Neighborhood Hits	351	Target Neighborhood Hits	1237	Shared Neighborhood Hits	96
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IRX5_HUMAN
θ value	5.27518 (rank : 253)	NC score	0.004911 (rank : 318)
Query Neighborhood Hits	351	Target Neighborhood Hits	362	Shared Neighborhood Hits	32
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

JIP1_HUMAN
θ value	5.27518 (rank : 254)	NC score	0.024929 (rank : 149)
Query Neighborhood Hits	351	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

K1802_HUMAN
θ value	5.27518 (rank : 255)	NC score	0.014657 (rank : 212)
Query Neighborhood Hits	351	Target Neighborhood Hits	1378	Shared Neighborhood Hits	113
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1802_MOUSE
θ value	5.27518 (rank : 256)	NC score	0.020280 (rank : 178)
Query Neighborhood Hits	351	Target Neighborhood Hits	1596	Shared Neighborhood Hits	123
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNS1_MOUSE
θ value	5.27518 (rank : 257)	NC score	0.141358 (rank : 54)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

LSP1_MOUSE
θ value	5.27518 (rank : 258)	NC score	0.013793 (rank : 217)
Query Neighborhood Hits	351	Target Neighborhood Hits	125	Shared Neighborhood Hits	20
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

MBB1A_HUMAN
θ value	5.27518 (rank : 259)	NC score	0.018576 (rank : 189)
Query Neighborhood Hits	351	Target Neighborhood Hits	665	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NEUL1_HUMAN
θ value	5.27518 (rank : 260)	NC score	0.005593 (rank : 305)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

PHLB1_MOUSE
θ value	5.27518 (rank : 261)	NC score	0.017920 (rank : 193)
Query Neighborhood Hits	351	Target Neighborhood Hits	678	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PPRB_HUMAN
θ value	5.27518 (rank : 262)	NC score	0.021841 (rank : 165)
Query Neighborhood Hits	351	Target Neighborhood Hits	311	Shared Neighborhood Hits	38
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PPRB_MOUSE
θ value	5.27518 (rank : 263)	NC score	0.021961 (rank : 163)
Query Neighborhood Hits	351	Target Neighborhood Hits	354	Shared Neighborhood Hits	47
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RAPH1_HUMAN
θ value	5.27518 (rank : 264)	NC score	0.023191 (rank : 157)
Query Neighborhood Hits	351	Target Neighborhood Hits	593	Shared Neighborhood Hits	66
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RNF12_HUMAN
θ value	5.27518 (rank : 265)	NC score	0.011266 (rank : 242)
Query Neighborhood Hits	351	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

SEM6C_MOUSE
θ value	5.27518 (rank : 266)	NC score	0.009386 (rank : 267)
Query Neighborhood Hits	351	Target Neighborhood Hits	352	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SSBP4_HUMAN
θ value	5.27518 (rank : 267)	NC score	0.016002 (rank : 206)
Query Neighborhood Hits	351	Target Neighborhood Hits	753	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

WDR67_MOUSE
θ value	5.27518 (rank : 268)	NC score	0.005404 (rank : 308)
Query Neighborhood Hits	351	Target Neighborhood Hits	476	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

WHRN_MOUSE
θ value	5.27518 (rank : 269)	NC score	0.005450 (rank : 307)
Query Neighborhood Hits	351	Target Neighborhood Hits	412	Shared Neighborhood Hits	27
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

ZN692_HUMAN
θ value	5.27518 (rank : 270)	NC score	-0.004196 (rank : 369)
Query Neighborhood Hits	351	Target Neighborhood Hits	808	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

3BP1_HUMAN
θ value	6.88961 (rank : 271)	NC score	0.015045 (rank : 211)
Query Neighborhood Hits	351	Target Neighborhood Hits	376	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ACM4_MOUSE
θ value	6.88961 (rank : 272)	NC score	-0.005218 (rank : 370)
Query Neighborhood Hits	351	Target Neighborhood Hits	894	Shared Neighborhood Hits	8
SwissProt Accessions	P32211, Q64056	Gene names	Chrm4, Chrm-4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4 (Mm4 mAChR).

BAP1_MOUSE
θ value	6.88961 (rank : 273)	NC score	0.010888 (rank : 248)
Query Neighborhood Hits	351	Target Neighborhood Hits	118	Shared Neighborhood Hits	22
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

BIM_HUMAN
θ value	6.88961 (rank : 274)	NC score	0.018326 (rank : 191)
Query Neighborhood Hits	351	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

BPA1_MOUSE
θ value	6.88961 (rank : 275)	NC score	0.003015 (rank : 334)
Query Neighborhood Hits	351	Target Neighborhood Hits	1477	Shared Neighborhood Hits	48
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CDR2_MOUSE
θ value	6.88961 (rank : 276)	NC score	0.005670 (rank : 303)
Query Neighborhood Hits	351	Target Neighborhood Hits	482	Shared Neighborhood Hits	21
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CO4A5_HUMAN
θ value	6.88961 (rank : 277)	NC score	0.011758 (rank : 237)
Query Neighborhood Hits	351	Target Neighborhood Hits	383	Shared Neighborhood Hits	43
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CP250_HUMAN
θ value	6.88961 (rank : 278)	NC score	0.002525 (rank : 339)
Query Neighborhood Hits	351	Target Neighborhood Hits	1805	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DMWD_MOUSE
θ value	6.88961 (rank : 279)	NC score	0.003635 (rank : 330)
Query Neighborhood Hits	351	Target Neighborhood Hits	282	Shared Neighborhood Hits	15
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

DNL1_HUMAN
θ value	6.88961 (rank : 280)	NC score	0.020821 (rank : 172)
Query Neighborhood Hits	351	Target Neighborhood Hits	216	Shared Neighborhood Hits	25
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

ETBR2_HUMAN
θ value	6.88961 (rank : 281)	NC score	0.002536 (rank : 338)
Query Neighborhood Hits	351	Target Neighborhood Hits	489	Shared Neighborhood Hits	5
SwissProt Accessions	O60883, Q86VP7	Gene names	GPR37L1, ETBRLP2
Domain Architecture
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

FBXL6_HUMAN
θ value	6.88961 (rank : 282)	NC score	0.004933 (rank : 317)
Query Neighborhood Hits	351	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FOXE2_HUMAN
θ value	6.88961 (rank : 283)	NC score	0.002571 (rank : 337)
Query Neighborhood Hits	351	Target Neighborhood Hits	236	Shared Neighborhood Hits	28
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

GA2L1_MOUSE
θ value	6.88961 (rank : 284)	NC score	0.023689 (rank : 154)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

HRX_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.019165 (rank : 184)
Query Neighborhood Hits	351	Target Neighborhood Hits	825	Shared Neighborhood Hits	72
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IG2AS_HUMAN
θ value	6.88961 (rank : 286)	NC score	0.015744 (rank : 208)
Query Neighborhood Hits	351	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q6U949, Q7Z712, Q9P2W0	Gene names	IGF2AS
Domain Architecture	No domain graphic available
Description	Putative insulin-like growth factor 2 antisense gene protein (IGF2-AS) (PEG8/IGF2AS protein).

KCNH2_MOUSE
θ value	6.88961 (rank : 287)	NC score	0.011654 (rank : 238)
Query Neighborhood Hits	351	Target Neighborhood Hits	165	Shared Neighborhood Hits	29
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH3_HUMAN
θ value	6.88961 (rank : 288)	NC score	0.007058 (rank : 289)
Query Neighborhood Hits	351	Target Neighborhood Hits	148	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	6.88961 (rank : 289)	NC score	0.006896 (rank : 292)
Query Neighborhood Hits	351	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

MAGE1_HUMAN
θ value	6.88961 (rank : 290)	NC score	0.025038 (rank : 148)
Query Neighborhood Hits	351	Target Neighborhood Hits	1389	Shared Neighborhood Hits	130
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MOES_HUMAN
θ value	6.88961 (rank : 291)	NC score	0.004769 (rank : 320)
Query Neighborhood Hits	351	Target Neighborhood Hits	892	Shared Neighborhood Hits	38
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NFAC3_HUMAN
θ value	6.88961 (rank : 292)	NC score	0.011000 (rank : 245)
Query Neighborhood Hits	351	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

NRG3_MOUSE
θ value	6.88961 (rank : 293)	NC score	0.011901 (rank : 236)
Query Neighborhood Hits	351	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

RFX1_HUMAN
θ value	6.88961 (rank : 294)	NC score	0.009582 (rank : 264)
Query Neighborhood Hits	351	Target Neighborhood Hits	256	Shared Neighborhood Hits	37
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RFX1_MOUSE
θ value	6.88961 (rank : 295)	NC score	0.007292 (rank : 285)
Query Neighborhood Hits	351	Target Neighborhood Hits	181	Shared Neighborhood Hits	19
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

SGIP1_HUMAN
θ value	6.88961 (rank : 296)	NC score	0.021490 (rank : 168)
Query Neighborhood Hits	351	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SPHK2_HUMAN
θ value	6.88961 (rank : 297)	NC score	0.009939 (rank : 258)
Query Neighborhood Hits	351	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

TAOK3_HUMAN
θ value	6.88961 (rank : 298)	NC score	-0.001734 (rank : 361)
Query Neighborhood Hits	351	Target Neighborhood Hits	1494	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TAOK3_MOUSE
θ value	6.88961 (rank : 299)	NC score	-0.001737 (rank : 362)
Query Neighborhood Hits	351	Target Neighborhood Hits	1458	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

TBX5_MOUSE
θ value	6.88961 (rank : 300)	NC score	0.001154 (rank : 346)
Query Neighborhood Hits	351	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TMM24_MOUSE
θ value	6.88961 (rank : 301)	NC score	0.011426 (rank : 240)
Query Neighborhood Hits	351	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

ULK1_HUMAN
θ value	6.88961 (rank : 302)	NC score	0.000346 (rank : 349)
Query Neighborhood Hits	351	Target Neighborhood Hits	1121	Shared Neighborhood Hits	58
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

US6NL_HUMAN
θ value	6.88961 (rank : 303)	NC score	0.009725 (rank : 261)
Query Neighborhood Hits	351	Target Neighborhood Hits	201	Shared Neighborhood Hits	33
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

VASP_MOUSE
θ value	6.88961 (rank : 304)	NC score	0.009993 (rank : 257)
Query Neighborhood Hits	351	Target Neighborhood Hits	195	Shared Neighborhood Hits	23
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ZBT17_MOUSE
θ value	6.88961 (rank : 305)	NC score	-0.005541 (rank : 371)
Query Neighborhood Hits	351	Target Neighborhood Hits	940	Shared Neighborhood Hits	23
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).

AB1IP_HUMAN
θ value	8.99809 (rank : 306)	NC score	0.007936 (rank : 280)
Query Neighborhood Hits	351	Target Neighborhood Hits	213	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ADA29_HUMAN
θ value	8.99809 (rank : 307)	NC score	0.000565 (rank : 347)
Query Neighborhood Hits	351	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ANKS6_MOUSE
θ value	8.99809 (rank : 308)	NC score	0.002235 (rank : 340)
Query Neighborhood Hits	351	Target Neighborhood Hits	435	Shared Neighborhood Hits	29
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASCC2_HUMAN
θ value	8.99809 (rank : 309)	NC score	0.005139 (rank : 315)
Query Neighborhood Hits	351	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1I8, Q4TT54, Q8TAZ0, Q9H711, Q9H9D6	Gene names	ASCC2, ASC1P100
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100).

ATBF1_MOUSE
θ value	8.99809 (rank : 310)	NC score	-0.001745 (rank : 363)
Query Neighborhood Hits	351	Target Neighborhood Hits	1841	Shared Neighborhood Hits	78
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BMP2_HUMAN
θ value	8.99809 (rank : 311)	NC score	-0.000057 (rank : 353)
Query Neighborhood Hits	351	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	P12643	Gene names	BMP2, BMP2A
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

BRSK2_HUMAN
θ value	8.99809 (rank : 312)	NC score	-0.002945 (rank : 366)
Query Neighborhood Hits	351	Target Neighborhood Hits	897	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

C1QR1_HUMAN
θ value	8.99809 (rank : 313)	NC score	0.003428 (rank : 331)
Query Neighborhood Hits	351	Target Neighborhood Hits	493	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CK024_HUMAN
θ value	8.99809 (rank : 314)	NC score	0.017890 (rank : 194)
Query Neighborhood Hits	351	Target Neighborhood Hits	408	Shared Neighborhood Hits	61
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CO2A1_MOUSE
θ value	8.99809 (rank : 315)	NC score	0.011563 (rank : 239)
Query Neighborhood Hits	351	Target Neighborhood Hits	483	Shared Neighborhood Hits	48
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CT116_HUMAN
θ value	8.99809 (rank : 316)	NC score	0.006454 (rank : 299)
Query Neighborhood Hits	351	Target Neighborhood Hits	294	Shared Neighborhood Hits	15
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

DDEF2_HUMAN
θ value	8.99809 (rank : 317)	NC score	0.006258 (rank : 301)
Query Neighborhood Hits	351	Target Neighborhood Hits	599	Shared Neighborhood Hits	37
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DPOLZ_HUMAN
θ value	8.99809 (rank : 318)	NC score	0.008207 (rank : 271)
Query Neighborhood Hits	351	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DYN3_HUMAN
θ value	8.99809 (rank : 319)	NC score	0.006594 (rank : 297)
Query Neighborhood Hits	351	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

ERG25_HUMAN
θ value	8.99809 (rank : 320)	NC score	0.004621 (rank : 322)
Query Neighborhood Hits	351	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q15800, Q32Q24	Gene names	SC4MOL, DESP4, ERG25
Domain Architecture
Description	C-4 methylsterol oxidase (EC 1.14.13.72) (Methylsterol monooxygenase).

FOXN1_HUMAN
θ value	8.99809 (rank : 321)	NC score	0.005320 (rank : 311)
Query Neighborhood Hits	351	Target Neighborhood Hits	377	Shared Neighborhood Hits	35
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GASP2_MOUSE
θ value	8.99809 (rank : 322)	NC score	0.007033 (rank : 290)
Query Neighborhood Hits	351	Target Neighborhood Hits	228	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

GP149_HUMAN
θ value	8.99809 (rank : 323)	NC score	0.004564 (rank : 323)
Query Neighborhood Hits	351	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

GPR75_MOUSE
θ value	8.99809 (rank : 324)	NC score	0.004423 (rank : 324)
Query Neighborhood Hits	351	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q6X632, Q3URC1, Q8BXP3	Gene names	Gpr75
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 75.

HXA2_MOUSE
θ value	8.99809 (rank : 325)	NC score	-0.000651 (rank : 357)
Query Neighborhood Hits	351	Target Neighborhood Hits	338	Shared Neighborhood Hits	11
SwissProt Accessions	P31245, Q149U3, Q920T8	Gene names	Hoxa2, Hox-1.11, Hoxa-2
Domain Architecture
Description	Homeobox protein Hox-A2 (Hox-1.11) (Hox1.11).

INVS_MOUSE
θ value	8.99809 (rank : 326)	NC score	0.008152 (rank : 272)
Query Neighborhood Hits	351	Target Neighborhood Hits	609	Shared Neighborhood Hits	60
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

JIP1_MOUSE
θ value	8.99809 (rank : 327)	NC score	0.022428 (rank : 161)
Query Neighborhood Hits	351	Target Neighborhood Hits	259	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MACOI_HUMAN
θ value	8.99809 (rank : 328)	NC score	0.004138 (rank : 326)
Query Neighborhood Hits	351	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	8.99809 (rank : 329)	NC score	0.003852 (rank : 328)
Query Neighborhood Hits	351	Target Neighborhood Hits	620	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MAVS_HUMAN
θ value	8.99809 (rank : 330)	NC score	0.012939 (rank : 225)
Query Neighborhood Hits	351	Target Neighborhood Hits	271	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

NCOA1_HUMAN
θ value	8.99809 (rank : 331)	NC score	0.002777 (rank : 335)
Query Neighborhood Hits	351	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOR2_HUMAN
θ value	8.99809 (rank : 332)	NC score	0.020693 (rank : 174)
Query Neighborhood Hits	351	Target Neighborhood Hits	870	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PI5PA_HUMAN
θ value	8.99809 (rank : 333)	NC score	0.018013 (rank : 192)
Query Neighborhood Hits	351	Target Neighborhood Hits	749	Shared Neighborhood Hits	103
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PUR8_MOUSE
θ value	8.99809 (rank : 334)	NC score	0.005303 (rank : 312)
Query Neighborhood Hits	351	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P54822	Gene names	Adsl, Adl
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

RAD9A_HUMAN
θ value	8.99809 (rank : 335)	NC score	0.004816 (rank : 319)
Query Neighborhood Hits	351	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q99638, Q6FI29, Q96C41	Gene names	RAD9A
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A) (hRAD9).

RBM14_MOUSE
θ value	8.99809 (rank : 336)	NC score	0.007148 (rank : 287)
Query Neighborhood Hits	351	Target Neighborhood Hits	217	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

RIN1_MOUSE
θ value	8.99809 (rank : 337)	NC score	0.003853 (rank : 327)
Query Neighborhood Hits	351	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

SHAN1_HUMAN
θ value	8.99809 (rank : 338)	NC score	0.008417 (rank : 269)
Query Neighborhood Hits	351	Target Neighborhood Hits	1041	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SPEG_MOUSE
θ value	8.99809 (rank : 339)	NC score	0.005356 (rank : 310)
Query Neighborhood Hits	351	Target Neighborhood Hits	1959	Shared Neighborhood Hits	114
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRRM2_HUMAN
θ value	8.99809 (rank : 340)	NC score	0.046025 (rank : 102)
Query Neighborhood Hits	351	Target Neighborhood Hits	1296	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ST2B1_HUMAN
θ value	8.99809 (rank : 341)	NC score	0.001247 (rank : 345)
Query Neighborhood Hits	351	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

SYN2_MOUSE
θ value	8.99809 (rank : 342)	NC score	0.011019 (rank : 244)
Query Neighborhood Hits	351	Target Neighborhood Hits	183	Shared Neighborhood Hits	29
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

TAF3_HUMAN
θ value	8.99809 (rank : 343)	NC score	0.010285 (rank : 256)
Query Neighborhood Hits	351	Target Neighborhood Hits	568	Shared Neighborhood Hits	38
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TCGAP_MOUSE
θ value	8.99809 (rank : 344)	NC score	0.007445 (rank : 284)
Query Neighborhood Hits	351	Target Neighborhood Hits	409	Shared Neighborhood Hits	37
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TMM24_HUMAN
θ value	8.99809 (rank : 345)	NC score	0.009620 (rank : 263)
Query Neighborhood Hits	351	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

TPTE2_HUMAN
θ value	8.99809 (rank : 346)	NC score	0.127501 (rank : 56)
Query Neighborhood Hits	351	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

TRPS1_MOUSE
θ value	8.99809 (rank : 347)	NC score	0.007065 (rank : 288)
Query Neighborhood Hits	351	Target Neighborhood Hits	609	Shared Neighborhood Hits	21
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

TTF1_MOUSE
θ value	8.99809 (rank : 348)	NC score	0.017247 (rank : 195)
Query Neighborhood Hits	351	Target Neighborhood Hits	277	Shared Neighborhood Hits	26
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

VGF_HUMAN
θ value	8.99809 (rank : 349)	NC score	0.009870 (rank : 259)
Query Neighborhood Hits	351	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

WASIP_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.030624 (rank : 129)
Query Neighborhood Hits	351	Target Neighborhood Hits	458	Shared Neighborhood Hits	61
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

YLPM1_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.028571 (rank : 136)
Query Neighborhood Hits	351	Target Neighborhood Hits	505	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

KCNA2_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.093862 (rank : 68)
Query Neighborhood Hits	351	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.094745 (rank : 65)
Query Neighborhood Hits	351	Target Neighborhood Hits	102	Shared Neighborhood Hits	42
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA3_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.085912 (rank : 73)
Query Neighborhood Hits	351	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.084940 (rank : 74)
Query Neighborhood Hits	351	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.074791 (rank : 80)
Query Neighborhood Hits	351	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.075192 (rank : 79)
Query Neighborhood Hits	351	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNC3_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.126106 (rank : 57)
Query Neighborhood Hits	351	Target Neighborhood Hits	256	Shared Neighborhood Hits	78
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.124078 (rank : 59)
Query Neighborhood Hits	351	Target Neighborhood Hits	173	Shared Neighborhood Hits	62
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG1_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.084312 (rank : 75)
Query Neighborhood Hits	351	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.081454 (rank : 77)
Query Neighborhood Hits	351	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.077524 (rank : 78)
Query Neighborhood Hits	351	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.072602 (rank : 81)
Query Neighborhood Hits	351	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.064025 (rank : 90)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	43
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.061632 (rank : 91)
Query Neighborhood Hits	351	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ4_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.090242 (rank : 69)
Query Neighborhood Hits	351	Target Neighborhood Hits	136	Shared Neighborhood Hits	48
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ5_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.070306 (rank : 83)
Query Neighborhood Hits	351	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

PKDRE_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.094989 (rank : 64)
Query Neighborhood Hits	351	Target Neighborhood Hits	64	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.070533 (rank : 82)
Query Neighborhood Hits	351	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TPTE_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.086210 (rank : 72)
Query Neighborhood Hits	351	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TRPV3_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.055525 (rank : 95)
Query Neighborhood Hits	351	Target Neighborhood Hits	198	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

Hits sorted by NC score

CAC1B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	351	Target Neighborhood Hits	351	Shared Neighborhood Hits	351
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_HUMAN
NC score	0.988419 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	351	Target Neighborhood Hits	257	Shared Neighborhood Hits	152
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_MOUSE
NC score	0.978448 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	351	Target Neighborhood Hits	267	Shared Neighborhood Hits	97
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1E_HUMAN
NC score	0.973819 (rank : 4)	θ value	0 (rank : 8)
Query Neighborhood Hits	351	Target Neighborhood Hits	148	Shared Neighborhood Hits	74
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
NC score	0.973342 (rank : 5)	θ value	0 (rank : 9)
Query Neighborhood Hits	351	Target Neighborhood Hits	167	Shared Neighborhood Hits	74
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_HUMAN
NC score	0.968587 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	351	Target Neighborhood Hits	387	Shared Neighborhood Hits	117
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1S_MOUSE
NC score	0.953077 (rank : 7)	θ value	0 (rank : 13)
Query Neighborhood Hits	351	Target Neighborhood Hits	98	Shared Neighborhood Hits	65
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_HUMAN
NC score	0.952583 (rank : 8)	θ value	0 (rank : 12)
Query Neighborhood Hits	351	Target Neighborhood Hits	92	Shared Neighborhood Hits	63
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1F_HUMAN
NC score	0.951368 (rank : 9)	θ value	0 (rank : 10)
Query Neighborhood Hits	351	Target Neighborhood Hits	141	Shared Neighborhood Hits	66
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1D_HUMAN
NC score	0.951249 (rank : 10)	θ value	0 (rank : 7)
Query Neighborhood Hits	351	Target Neighborhood Hits	118	Shared Neighborhood Hits	63
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1F_MOUSE
NC score	0.951216 (rank : 11)	θ value	0 (rank : 11)
Query Neighborhood Hits	351	Target Neighborhood Hits	142	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1C_MOUSE
NC score	0.949188 (rank : 12)	θ value	0 (rank : 6)
Query Neighborhood Hits	351	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.947621 (rank : 13)	θ value	0 (rank : 5)
Query Neighborhood Hits	351	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1I_HUMAN
NC score	0.892839 (rank : 14)	θ value	3.13423e-69 (rank : 17)
Query Neighborhood Hits	351	Target Neighborhood Hits	138	Shared Neighborhood Hits	71
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.871780 (rank : 15)	θ value	1.31681e-67 (rank : 23)
Query Neighborhood Hits	351	Target Neighborhood Hits	230	Shared Neighborhood Hits	93
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.867457 (rank : 16)	θ value	3.83135e-67 (rank : 26)
Query Neighborhood Hits	351	Target Neighborhood Hits	307	Shared Neighborhood Hits	93
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC11A_MOUSE
NC score	0.858806 (rank : 17)	θ value	5.7252e-63 (rank : 29)
Query Neighborhood Hits	351	Target Neighborhood Hits	116	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.858448 (rank : 18)	θ value	1.31681e-67 (rank : 24)
Query Neighborhood Hits	351	Target Neighborhood Hits	111	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

CAC1G_HUMAN
NC score	0.858435 (rank : 19)	θ value	2.93355e-67 (rank : 25)
Query Neighborhood Hits	351	Target Neighborhood Hits	587	Shared Neighborhood Hits	139
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SCN5A_HUMAN
NC score	0.853561 (rank : 20)	θ value	1.00825e-67 (rank : 22)
Query Neighborhood Hits	351	Target Neighborhood Hits	145	Shared Neighborhood Hits	59
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN4A_HUMAN
NC score	0.852725 (rank : 21)	θ value	2.03155e-68 (rank : 19)
Query Neighborhood Hits	351	Target Neighborhood Hits	133	Shared Neighborhood Hits	66
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN7A_HUMAN
NC score	0.850112 (rank : 22)	θ value	8.85319e-56 (rank : 30)
Query Neighborhood Hits	351	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SC10A_MOUSE
NC score	0.844288 (rank : 23)	θ value	3.83135e-67 (rank : 27)
Query Neighborhood Hits	351	Target Neighborhood Hits	107	Shared Neighborhood Hits	64
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN3A_HUMAN
NC score	0.844276 (rank : 24)	θ value	9.11921e-69 (rank : 18)
Query Neighborhood Hits	351	Target Neighborhood Hits	115	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN8A_HUMAN
NC score	0.843001 (rank : 25)	θ value	7.71989e-68 (rank : 21)
Query Neighborhood Hits	351	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN2A_HUMAN
NC score	0.842327 (rank : 26)	θ value	8.81223e-72 (rank : 14)
Query Neighborhood Hits	351	Target Neighborhood Hits	157	Shared Neighborhood Hits	54
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN9A_HUMAN
NC score	0.842207 (rank : 27)	θ value	1.96316e-71 (rank : 15)
Query Neighborhood Hits	351	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN1A_HUMAN
NC score	0.841975 (rank : 28)	θ value	1.66191e-70 (rank : 16)
Query Neighborhood Hits	351	Target Neighborhood Hits	148	Shared Neighborhood Hits	61
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN8A_MOUSE
NC score	0.840695 (rank : 29)	θ value	2.03155e-68 (rank : 20)
Query Neighborhood Hits	351	Target Neighborhood Hits	136	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC10A_HUMAN
NC score	0.839589 (rank : 30)	θ value	8.83269e-64 (rank : 28)
Query Neighborhood Hits	351	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

PK2L2_HUMAN
NC score	0.368093 (rank : 31)	θ value	4.1701e-05 (rank : 32)
Query Neighborhood Hits	351	Target Neighborhood Hits	90	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.342641 (rank : 32)	θ value	5.44631e-05 (rank : 33)
Query Neighborhood Hits	351	Target Neighborhood Hits	132	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.334611 (rank : 33)	θ value	0.000461057 (rank : 37)
Query Neighborhood Hits	351	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.332206 (rank : 34)	θ value	1.09739e-05 (rank : 31)
Query Neighborhood Hits	351	Target Neighborhood Hits	99	Shared Neighborhood Hits	45
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.319561 (rank : 35)	θ value	9.29e-05 (rank : 34)
Query Neighborhood Hits	351	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.248995 (rank : 36)	θ value	0.00134147 (rank : 42)
Query Neighborhood Hits	351	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.240217 (rank : 37)	θ value	0.00035302 (rank : 35)
Query Neighborhood Hits	351	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
NC score	0.218013 (rank : 38)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	351	Target Neighborhood Hits	212	Shared Neighborhood Hits	71
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.214166 (rank : 39)	θ value	0.0252991 (rank : 60)
Query Neighborhood Hits	351	Target Neighborhood Hits	130	Shared Neighborhood Hits	62
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.210092 (rank : 40)	θ value	0.0330416 (rank : 63)
Query Neighborhood Hits	351	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_MOUSE
NC score	0.203944 (rank : 41)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	351	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.203883 (rank : 42)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	351	Target Neighborhood Hits	169	Shared Neighborhood Hits	65
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCND3_MOUSE
NC score	0.198597 (rank : 43)	θ value	0.00102713 (rank : 41)
Query Neighborhood Hits	351	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.198480 (rank : 44)	θ value	0.00102713 (rank : 40)
Query Neighborhood Hits	351	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND2_MOUSE
NC score	0.192833 (rank : 45)	θ value	0.00102713 (rank : 39)
Query Neighborhood Hits	351	Target Neighborhood Hits	156	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.192667 (rank : 46)	θ value	0.00102713 (rank : 38)
Query Neighborhood Hits	351	Target Neighborhood Hits	154	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.183439 (rank : 47)	θ value	0.000461057 (rank : 36)
Query Neighborhood Hits	351	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNS3_HUMAN
NC score	0.182501 (rank : 48)	θ value	0.21417 (rank : 88)
Query Neighborhood Hits	351	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND1_HUMAN
NC score	0.178959 (rank : 49)	θ value	0.00298849 (rank : 44)
Query Neighborhood Hits	351	Target Neighborhood Hits	160	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS1_HUMAN
NC score	0.158272 (rank : 50)	θ value	0.62314 (rank : 119)
Query Neighborhood Hits	351	Target Neighborhood Hits	116	Shared Neighborhood Hits	60
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.150218 (rank : 51)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	351	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.148311 (rank : 52)	θ value	0.0193708 (rank : 54)
Query Neighborhood Hits	351	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.144426 (rank : 53)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	351	Target Neighborhood Hits	141	Shared Neighborhood Hits	58
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNS1_MOUSE
NC score	0.141358 (rank : 54)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC4_MOUSE
NC score	0.136948 (rank : 55)	θ value	0.163984 (rank : 81)
Query Neighborhood Hits	351	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

TPTE2_HUMAN
NC score	0.127501 (rank : 56)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	351	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNC3_HUMAN
NC score	0.126106 (rank : 57)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	351	Target Neighborhood Hits	256	Shared Neighborhood Hits	78
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG3_HUMAN
NC score	0.124219 (rank : 58)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	351	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNC3_MOUSE
NC score	0.124078 (rank : 59)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	351	Target Neighborhood Hits	173	Shared Neighborhood Hits	62
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG3_MOUSE
NC score	0.120872 (rank : 60)	θ value	0.62314 (rank : 118)
Query Neighborhood Hits	351	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNA1_MOUSE
NC score	0.106148 (rank : 61)	θ value	0.0252991 (rank : 59)
Query Neighborhood Hits	351	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.104223 (rank : 62)	θ value	0.0431538 (rank : 67)
Query Neighborhood Hits	351	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA6_MOUSE
NC score	0.100880 (rank : 63)	θ value	0.0148317 (rank : 48)
Query Neighborhood Hits	351	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

PKDRE_HUMAN
NC score	0.094989 (rank : 64)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	351	Target Neighborhood Hits	64	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNA2_MOUSE
NC score	0.094745 (rank : 65)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	351	Target Neighborhood Hits	102	Shared Neighborhood Hits	42
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA6_HUMAN
NC score	0.094518 (rank : 66)	θ value	0.125558 (rank : 78)
Query Neighborhood Hits	351	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

MCLN2_MOUSE
NC score	0.094414 (rank : 67)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	351	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

KCNA2_HUMAN
NC score	0.093862 (rank : 68)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	351	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNQ4_HUMAN
NC score	0.090242 (rank : 69)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	351	Target Neighborhood Hits	136	Shared Neighborhood Hits	48
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNA5_MOUSE
NC score	0.089705 (rank : 70)	θ value	3.0926 (rank : 206)
Query Neighborhood Hits	351	Target Neighborhood Hits	119	Shared Neighborhood Hits	43
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNQ1_MOUSE
NC score	0.086397 (rank : 71)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	351	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

TPTE_HUMAN
NC score	0.086210 (rank : 72)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	351	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNA3_HUMAN
NC score	0.085912 (rank : 73)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	351	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
NC score	0.084940 (rank : 74)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	351	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNG1_HUMAN
NC score	0.084312 (rank : 75)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	351	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNA5_HUMAN
NC score	0.083893 (rank : 76)	θ value	3.0926 (rank : 205)
Query Neighborhood Hits	351	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNG2_HUMAN
NC score	0.081454 (rank : 77)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	351	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
NC score	0.077524 (rank : 78)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	351	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNA4_MOUSE
NC score	0.075192 (rank : 79)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	351	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.074791 (rank : 80)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	351	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ1_HUMAN
NC score	0.072602 (rank : 81)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	351	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

PKDRE_MOUSE
NC score	0.070533 (rank : 82)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	351	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNQ5_HUMAN
NC score	0.070306 (rank : 83)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	351	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TRPM8_MOUSE
NC score	0.069565 (rank : 84)	θ value	0.0113563 (rank : 47)
Query Neighborhood Hits	351	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

MCLN2_HUMAN
NC score	0.069372 (rank : 85)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	351	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

NPBL_MOUSE
NC score	0.068189 (rank : 86)	θ value	0.0148317 (rank : 51)
Query Neighborhood Hits	351	Target Neighborhood Hits	1041	Shared Neighborhood Hits	83
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

KCNQ3_HUMAN
NC score	0.067413 (rank : 87)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	41
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
NC score	0.066059 (rank : 88)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	351	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

TRPM8_HUMAN
NC score	0.064623 (rank : 89)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	351	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

KCNQ2_HUMAN
NC score	0.064025 (rank : 90)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	43
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.061632 (rank : 91)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	351	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

MCLN3_MOUSE
NC score	0.058651 (rank : 92)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	351	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4F0, Q8BS73, Q8BSG1, Q8CDB2	Gene names	Mcoln3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

SRRM1_MOUSE
NC score	0.058440 (rank : 93)	θ value	0.365318 (rank : 102)
Query Neighborhood Hits	351	Target Neighborhood Hits	966	Shared Neighborhood Hits	118
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NIPBL_HUMAN
NC score	0.057702 (rank : 94)	θ value	0.163984 (rank : 84)
Query Neighborhood Hits	351	Target Neighborhood Hits	1311	Shared Neighborhood Hits	96
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TRPV3_HUMAN
NC score	0.055525 (rank : 95)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	351	Target Neighborhood Hits	198	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

MCLN3_HUMAN
NC score	0.053485 (rank : 96)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	351	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDD5, Q5T4H5, Q5T4H6, Q9NV09	Gene names	MCOLN3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

TRPC4_HUMAN
NC score	0.051947 (rank : 97)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	351	Target Neighborhood Hits	140	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.050222 (rank : 98)	θ value	0.0252991 (rank : 62)
Query Neighborhood Hits	351	Target Neighborhood Hits	141	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

SRRM1_HUMAN
NC score	0.049158 (rank : 99)	θ value	0.62314 (rank : 123)
Query Neighborhood Hits	351	Target Neighborhood Hits	690	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TARA_HUMAN
NC score	0.049149 (rank : 100)	θ value	0.21417 (rank : 92)
Query Neighborhood Hits	351	Target Neighborhood Hits	1626	Shared Neighborhood Hits	129
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAF4_HUMAN
NC score	0.046551 (rank : 101)	θ value	0.21417 (rank : 91)
Query Neighborhood Hits	351	Target Neighborhood Hits	687	Shared Neighborhood Hits	83
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SRRM2_HUMAN
NC score	0.046025 (rank : 102)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	351	Target Neighborhood Hits	1296	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MCLN1_MOUSE
NC score	0.045788 (rank : 103)	θ value	0.813845 (rank : 130)
Query Neighborhood Hits	351	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q99J21	Gene names	Mcoln1
Domain Architecture	No domain graphic available
Description	Mucolipin-1 (Mucolipidin).

DJBP_MOUSE
NC score	0.045510 (rank : 104)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	351	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

BSN_MOUSE
NC score	0.045299 (rank : 105)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	351	Target Neighborhood Hits	2057	Shared Neighborhood Hits	171
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD55_MOUSE
NC score	0.044950 (rank : 106)	θ value	0.0431538 (rank : 65)
Query Neighborhood Hits	351	Target Neighborhood Hits	519	Shared Neighborhood Hits	33
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

MCLN1_HUMAN
NC score	0.044780 (rank : 107)	θ value	3.0926 (rank : 207)
Query Neighborhood Hits	351	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZU1, Q7Z4F7, Q9H292, Q9H4B3, Q9H4B5	Gene names	MCOLN1, ML4
Domain Architecture	No domain graphic available
Description	Mucolipin-1 (Mucolipidin) (MG-2).

FILA_HUMAN
NC score	0.044774 (rank : 108)	θ value	0.0563607 (rank : 70)
Query Neighborhood Hits	351	Target Neighborhood Hits	685	Shared Neighborhood Hits	55
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

DACT1_HUMAN
NC score	0.043657 (rank : 109)	θ value	0.163984 (rank : 80)
Query Neighborhood Hits	351	Target Neighborhood Hits	228	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

GSCR1_HUMAN
NC score	0.042894 (rank : 110)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	351	Target Neighborhood Hits	674	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

RFIP5_MOUSE
NC score	0.040841 (rank : 111)	θ value	0.0193708 (rank : 56)
Query Neighborhood Hits	351	Target Neighborhood Hits	126	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

ARI1A_HUMAN
NC score	0.038910 (rank : 112)	θ value	0.0252991 (rank : 58)
Query Neighborhood Hits	351	Target Neighborhood Hits	787	Shared Neighborhood Hits	85
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BIM_MOUSE
NC score	0.038688 (rank : 113)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	351	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	O54918, O54919, O54920	Gene names	Bcl2l11, Bim
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

RGS3_MOUSE
NC score	0.037895 (rank : 114)	θ value	0.365318 (rank : 100)
Query Neighborhood Hits	351	Target Neighborhood Hits	1621	Shared Neighborhood Hits	153
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BSN_HUMAN
NC score	0.037677 (rank : 115)	θ value	0.62314 (rank : 116)
Query Neighborhood Hits	351	Target Neighborhood Hits	1537	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NACAM_MOUSE
NC score	0.037510 (rank : 116)	θ value	0.47712 (rank : 107)
Query Neighborhood Hits	351	Target Neighborhood Hits	1866	Shared Neighborhood Hits	156
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PHF1_MOUSE
NC score	0.036114 (rank : 117)	θ value	0.00134147 (rank : 43)
Query Neighborhood Hits	351	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

TARA_MOUSE
NC score	0.035753 (rank : 118)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	351	Target Neighborhood Hits	1133	Shared Neighborhood Hits	99
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ATX7_HUMAN
NC score	0.035681 (rank : 119)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	351	Target Neighborhood Hits	351	Shared Neighborhood Hits	58
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

SYN1_HUMAN
NC score	0.035404 (rank : 120)	θ value	2.36792 (rank : 193)
Query Neighborhood Hits	351	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

YLPM1_HUMAN
NC score	0.035385 (rank : 121)	θ value	0.47712 (rank : 115)
Query Neighborhood Hits	351	Target Neighborhood Hits	670	Shared Neighborhood Hits	74
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SFRIP_HUMAN
NC score	0.035156 (rank : 122)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	351	Target Neighborhood Hits	530	Shared Neighborhood Hits	55
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CCD55_HUMAN
NC score	0.033784 (rank : 123)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	351	Target Neighborhood Hits	513	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

TTC16_HUMAN
NC score	0.033499 (rank : 124)	θ value	0.62314 (rank : 125)
Query Neighborhood Hits	351	Target Neighborhood Hits	417	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

MBD5_HUMAN
NC score	0.033101 (rank : 125)	θ value	0.813845 (rank : 129)
Query Neighborhood Hits	351	Target Neighborhood Hits	176	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MINT_MOUSE
NC score	0.032365 (rank : 126)	θ value	3.0926 (rank : 209)
Query Neighborhood Hits	351	Target Neighborhood Hits	1514	Shared Neighborhood Hits	123
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL2_HUMAN
NC score	0.032146 (rank : 127)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	351	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OXR1_MOUSE
NC score	0.031847 (rank : 128)	θ value	0.0193708 (rank : 55)
Query Neighborhood Hits	351	Target Neighborhood Hits	516	Shared Neighborhood Hits	43
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

WASIP_HUMAN
NC score	0.030624 (rank : 129)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	351	Target Neighborhood Hits	458	Shared Neighborhood Hits	61
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SNIP1_MOUSE
NC score	0.030113 (rank : 130)	θ value	0.163984 (rank : 85)
Query Neighborhood Hits	351	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

SMOO_HUMAN
NC score	0.030044 (rank : 131)	θ value	0.279714 (rank : 97)
Query Neighborhood Hits	351	Target Neighborhood Hits	391	Shared Neighborhood Hits	45
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TAU_MOUSE
NC score	0.029843 (rank : 132)	θ value	0.62314 (rank : 124)
Query Neighborhood Hits	351	Target Neighborhood Hits	502	Shared Neighborhood Hits	75
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ATX7_MOUSE
NC score	0.029428 (rank : 133)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	351	Target Neighborhood Hits	328	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

PININ_HUMAN
NC score	0.028634 (rank : 134)	θ value	0.47712 (rank : 109)
Query Neighborhood Hits	351	Target Neighborhood Hits	753	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

RENT1_MOUSE
NC score	0.028629 (rank : 135)	θ value	0.21417 (rank : 90)
Query Neighborhood Hits	351	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

YLPM1_MOUSE
NC score	0.028571 (rank : 136)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	351	Target Neighborhood Hits	505	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

SETBP_MOUSE
NC score	0.028317 (rank : 137)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	351	Target Neighborhood Hits	352	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

RENT1_HUMAN
NC score	0.028271 (rank : 138)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	351	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

TREF1_HUMAN
NC score	0.028172 (rank : 139)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	351	Target Neighborhood Hits	651	Shared Neighborhood Hits	28
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

ATX1_MOUSE
NC score	0.028010 (rank : 140)	θ value	0.21417 (rank : 86)
Query Neighborhood Hits	351	Target Neighborhood Hits	264	Shared Neighborhood Hits	32
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

MAP4_MOUSE
NC score	0.027489 (rank : 141)	θ value	1.38821 (rank : 149)
Query Neighborhood Hits	351	Target Neighborhood Hits	409	Shared Neighborhood Hits	55
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SYN3_HUMAN
NC score	0.027199 (rank : 142)	θ value	2.36792 (rank : 194)
Query Neighborhood Hits	351	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

SGIP1_MOUSE
NC score	0.026819 (rank : 143)	θ value	3.0926 (rank : 212)
Query Neighborhood Hits	351	Target Neighborhood Hits	180	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TOIP2_MOUSE
NC score	0.025765 (rank : 144)	θ value	0.365318 (rank : 103)
Query Neighborhood Hits	351	Target Neighborhood Hits	115	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

SNPC4_HUMAN
NC score	0.025368 (rank : 145)	θ value	3.0926 (rank : 213)
Query Neighborhood Hits	351	Target Neighborhood Hits	589	Shared Neighborhood Hits	78
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

ARI3A_MOUSE
NC score	0.025274 (rank : 146)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	351	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q62431	Gene names	Arid3a, Dri1, Dril1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (Dead ringer-like protein 1) (B-cell regulator of IgH transcription) (Bright).

JPH2_HUMAN
NC score	0.025149 (rank : 147)	θ value	1.81305 (rank : 165)
Query Neighborhood Hits	351	Target Neighborhood Hits	639	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MAGE1_HUMAN
NC score	0.025038 (rank : 148)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	351	Target Neighborhood Hits	1389	Shared Neighborhood Hits	130
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

JIP1_HUMAN
NC score	0.024929 (rank : 149)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	351	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

CAP1_HUMAN
NC score	0.024739 (rank : 150)	θ value	0.279714 (rank : 94)
Query Neighborhood Hits	351	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q01518, Q53HR7, Q5T0S1, Q6I9U6	Gene names	CAP1, CAP
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CIC_HUMAN
NC score	0.024347 (rank : 151)	θ value	0.813845 (rank : 126)
Query Neighborhood Hits	351	Target Neighborhood Hits	992	Shared Neighborhood Hits	106
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SYP2L_HUMAN
NC score	0.024088 (rank : 152)	θ value	0.47712 (rank : 114)
Query Neighborhood Hits	351	Target Neighborhood Hits	400	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PPAC2_MOUSE
NC score	0.024065 (rank : 153)	θ value	0.813845 (rank : 132)
Query Neighborhood Hits	351	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4F2	Gene names	Ppapdc2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

GA2L1_MOUSE
NC score	0.023689 (rank : 154)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

CIC_MOUSE
NC score	0.023671 (rank : 155)	θ value	0.813845 (rank : 127)
Query Neighborhood Hits	351	Target Neighborhood Hits	742	Shared Neighborhood Hits	85
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ASTL_HUMAN
NC score	0.023661 (rank : 156)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	351	Target Neighborhood Hits	252	Shared Neighborhood Hits	40
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

RAPH1_HUMAN
NC score	0.023191 (rank : 157)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	351	Target Neighborhood Hits	593	Shared Neighborhood Hits	66
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CABIN_HUMAN
NC score	0.022889 (rank : 158)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	351	Target Neighborhood Hits	490	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

SF3B4_HUMAN
NC score	0.022711 (rank : 159)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	351	Target Neighborhood Hits	445	Shared Neighborhood Hits	45
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

CBP_HUMAN
NC score	0.022596 (rank : 160)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	351	Target Neighborhood Hits	941	Shared Neighborhood Hits	100
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

JIP1_MOUSE
NC score	0.022428 (rank : 161)	θ value	8.99809 (rank : 327)
Query Neighborhood Hits	351	Target Neighborhood Hits	259	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

ZN750_MOUSE
NC score	0.022084 (rank : 162)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	351	Target Neighborhood Hits	346	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

PPRB_MOUSE
NC score	0.021961 (rank : 163)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	351	Target Neighborhood Hits	354	Shared Neighborhood Hits	47
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SYP2L_MOUSE
NC score	0.021904 (rank : 164)	θ value	1.06291 (rank : 142)
Query Neighborhood Hits	351	Target Neighborhood Hits	289	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PPRB_HUMAN
NC score	0.021841 (rank : 165)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	351	Target Neighborhood Hits	311	Shared Neighborhood Hits	38
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

CD248_HUMAN
NC score	0.021753 (rank : 166)	θ value	0.0431538 (rank : 66)
Query Neighborhood Hits	351	Target Neighborhood Hits	679	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

PHLB1_HUMAN
NC score	0.021751 (rank : 167)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	351	Target Neighborhood Hits	1038	Shared Neighborhood Hits	80
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SGIP1_HUMAN
NC score	0.021490 (rank : 168)	θ value	6.88961 (rank : 296)
Query Neighborhood Hits	351	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

ARI3A_HUMAN
NC score	0.021390 (rank : 169)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	351	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

TRHY_HUMAN
NC score	0.021243 (rank : 170)	θ value	0.00665767 (rank : 46)
Query Neighborhood Hits	351	Target Neighborhood Hits	1385	Shared Neighborhood Hits	50
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

PELP1_MOUSE
NC score	0.021226 (rank : 171)	θ value	0.365318 (rank : 99)
Query Neighborhood Hits	351	Target Neighborhood Hits	709	Shared Neighborhood Hits	68
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

DNL1_HUMAN
NC score	0.020821 (rank : 172)	θ value	6.88961 (rank : 280)
Query Neighborhood Hits	351	Target Neighborhood Hits	216	Shared Neighborhood Hits	25
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

PHLA1_HUMAN
NC score	0.020766 (rank : 173)	θ value	0.47712 (rank : 108)
Query Neighborhood Hits	351	Target Neighborhood Hits	121	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

NCOR2_HUMAN
NC score	0.020693 (rank : 174)	θ value	8.99809 (rank : 332)
Query Neighborhood Hits	351	Target Neighborhood Hits	870	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

JIP2_MOUSE
NC score	0.020630 (rank : 175)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	351	Target Neighborhood Hits	144	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

SET1A_HUMAN
NC score	0.020381 (rank : 176)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	351	Target Neighborhood Hits	690	Shared Neighborhood Hits	61
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MEA1_MOUSE
NC score	0.020329 (rank : 177)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	351	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q64327	Gene names	Mea1, Mea
Domain Architecture
Description	Male-enhanced antigen 1 (MEA-1).

K1802_MOUSE
NC score	0.020280 (rank : 178)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	351	Target Neighborhood Hits	1596	Shared Neighborhood Hits	123
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RB15B_MOUSE
NC score	0.020250 (rank : 179)	θ value	0.21417 (rank : 89)
Query Neighborhood Hits	351	Target Neighborhood Hits	284	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

TRPM7_MOUSE
NC score	0.020051 (rank : 180)	θ value	4.03905 (rank : 244)
Query Neighborhood Hits	351	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TREF1_MOUSE
NC score	0.019632 (rank : 181)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	351	Target Neighborhood Hits	682	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

PRG4_HUMAN
NC score	0.019488 (rank : 182)	θ value	3.0926 (rank : 211)
Query Neighborhood Hits	351	Target Neighborhood Hits	764	Shared Neighborhood Hits	65
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

T22D2_HUMAN
NC score	0.019347 (rank : 183)	θ value	1.38821 (rank : 155)
Query Neighborhood Hits	351	Target Neighborhood Hits	250	Shared Neighborhood Hits	29
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

HRX_HUMAN
NC score	0.019165 (rank : 184)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	351	Target Neighborhood Hits	825	Shared Neighborhood Hits	72
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SPTN4_HUMAN
NC score	0.019109 (rank : 185)	θ value	0.00509761 (rank : 45)
Query Neighborhood Hits	351	Target Neighborhood Hits	570	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

MEA1_HUMAN
NC score	0.019102 (rank : 186)	θ value	3.0926 (rank : 208)
Query Neighborhood Hits	351	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q16626, Q5TC36, Q9BV01	Gene names	MEA1, MEA
Domain Architecture
Description	Male-enhanced antigen 1 (MEA-1).

IRS2_MOUSE
NC score	0.019057 (rank : 187)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	351	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

HCN4_HUMAN
NC score	0.018816 (rank : 188)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	351	Target Neighborhood Hits	303	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

MBB1A_HUMAN
NC score	0.018576 (rank : 189)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	351	Target Neighborhood Hits	665	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

HCN4_MOUSE
NC score	0.018406 (rank : 190)	θ value	0.62314 (rank : 117)
Query Neighborhood Hits	351	Target Neighborhood Hits	284	Shared Neighborhood Hits	47
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

BIM_HUMAN
NC score	0.018326 (rank : 191)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	351	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

PI5PA_HUMAN
NC score	0.018013 (rank : 192)	θ value	8.99809 (rank : 333)
Query Neighborhood Hits	351	Target Neighborhood Hits	749	Shared Neighborhood Hits	103
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PHLB1_MOUSE
NC score	0.017920 (rank : 193)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	351	Target Neighborhood Hits	678	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CK024_HUMAN
NC score	0.017890 (rank : 194)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	351	Target Neighborhood Hits	408	Shared Neighborhood Hits	61
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

TTF1_MOUSE
NC score	0.017247 (rank : 195)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	351	Target Neighborhood Hits	277	Shared Neighborhood Hits	26
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

ANK2_HUMAN
NC score	0.017205 (rank : 196)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	351	Target Neighborhood Hits	1615	Shared Neighborhood Hits	132
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BAP1_HUMAN
NC score	0.017129 (rank : 197)	θ value	2.36792 (rank : 177)
Query Neighborhood Hits	351	Target Neighborhood Hits	106	Shared Neighborhood Hits	18
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

CAP1_MOUSE
NC score	0.017124 (rank : 198)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	351	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

PO6F2_HUMAN
NC score	0.016798 (rank : 199)	θ value	0.47712 (rank : 110)
Query Neighborhood Hits	351	Target Neighborhood Hits	618	Shared Neighborhood Hits	46
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

TTC14_HUMAN
NC score	0.016441 (rank : 200)	θ value	1.38821 (rank : 157)
Query Neighborhood Hits	351	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

MEF2B_MOUSE
NC score	0.016328 (rank : 201)	θ value	0.813845 (rank : 131)
Query Neighborhood Hits	351	Target Neighborhood Hits	218	Shared Neighborhood Hits	30
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

NRG3_HUMAN
NC score	0.016326 (rank : 202)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	351	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

DGKK_HUMAN
NC score	0.016228 (rank : 203)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	351	Target Neighborhood Hits	378	Shared Neighborhood Hits	38
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

GLU2B_MOUSE
NC score	0.016202 (rank : 204)	θ value	0.813845 (rank : 128)
Query Neighborhood Hits	351	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

RNF12_MOUSE
NC score	0.016026 (rank : 205)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	351	Target Neighborhood Hits	159	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

SSBP4_HUMAN
NC score	0.016002 (rank : 206)	θ value	5.27518 (rank : 267)
Query Neighborhood Hits	351	Target Neighborhood Hits	753	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

UBE4B_HUMAN
NC score	0.015960 (rank : 207)	θ value	4.03905 (rank : 245)
Query Neighborhood Hits	351	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

IG2AS_HUMAN
NC score	0.015744 (rank : 208)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	351	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q6U949, Q7Z712, Q9P2W0	Gene names	IGF2AS
Domain Architecture	No domain graphic available
Description	Putative insulin-like growth factor 2 antisense gene protein (IGF2-AS) (PEG8/IGF2AS protein).

DYN1_HUMAN
NC score	0.015525 (rank : 209)	θ value	1.81305 (rank : 164)
Query Neighborhood Hits	351	Target Neighborhood Hits	216	Shared Neighborhood Hits	37
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

PO121_HUMAN
NC score	0.015207 (rank : 210)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	351	Target Neighborhood Hits	344	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

3BP1_HUMAN
NC score	0.015045 (rank : 211)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	351	Target Neighborhood Hits	376	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

K1802_HUMAN
NC score	0.014657 (rank : 212)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	351	Target Neighborhood Hits	1378	Shared Neighborhood Hits	113
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

GP160_HUMAN
NC score	0.014418 (rank : 213)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	351	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ42	Gene names	GPR160, GPCR150
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 160.

SDPR_MOUSE
NC score	0.014269 (rank : 214)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	351	Target Neighborhood Hits	485	Shared Neighborhood Hits	24
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

PAX9_HUMAN
NC score	0.014050 (rank : 215)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	351	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

PTPRN_MOUSE
NC score	0.013815 (rank : 216)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	351	Target Neighborhood Hits	240	Shared Neighborhood Hits	23
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

LSP1_MOUSE
NC score	0.013793 (rank : 217)	θ value	5.27518 (rank : 258)
Query Neighborhood Hits	351	Target Neighborhood Hits	125	Shared Neighborhood Hits	20
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

CO2A1_HUMAN
NC score	0.013772 (rank : 218)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	351	Target Neighborhood Hits	486	Shared Neighborhood Hits	51
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

PTN23_MOUSE
NC score	0.013562 (rank : 219)	θ value	0.47712 (rank : 111)
Query Neighborhood Hits	351	Target Neighborhood Hits	726	Shared Neighborhood Hits	69
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SPESP_MOUSE
NC score	0.013303 (rank : 220)	θ value	3.0926 (rank : 215)
Query Neighborhood Hits	351	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

SSBP3_HUMAN
NC score	0.013287 (rank : 221)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	351	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.013287 (rank : 222)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	351	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

CS029_HUMAN
NC score	0.013229 (rank : 223)	θ value	1.81305 (rank : 162)
Query Neighborhood Hits	351	Target Neighborhood Hits	329	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

CENG1_HUMAN
NC score	0.012976 (rank : 224)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	351	Target Neighborhood Hits	544	Shared Neighborhood Hits	32
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

MAVS_HUMAN
NC score	0.012939 (rank : 225)	θ value	8.99809 (rank : 330)
Query Neighborhood Hits	351	Target Neighborhood Hits	271	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

SPHK2_MOUSE
NC score	0.012850 (rank : 226)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	351	Target Neighborhood Hits	78	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

CEND1_HUMAN
NC score	0.012735 (rank : 227)	θ value	0.125558 (rank : 77)
Query Neighborhood Hits	351	Target Neighborhood Hits	284	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

NFAC3_MOUSE
NC score	0.012699 (rank : 228)	θ value	0.62314 (rank : 121)
Query Neighborhood Hits	351	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

ZIM10_HUMAN
NC score	0.012596 (rank : 229)	θ value	2.36792 (rank : 196)
Query Neighborhood Hits	351	Target Neighborhood Hits	577	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZC3H3_MOUSE
NC score	0.012474 (rank : 230)	θ value	3.0926 (rank : 217)
Query Neighborhood Hits	351	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

K0460_HUMAN
NC score	0.012374 (rank : 231)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	351	Target Neighborhood Hits	357	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

ANKZ1_MOUSE
NC score	0.012247 (rank : 232)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	351	Target Neighborhood Hits	208	Shared Neighborhood Hits	13
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CCD1A_HUMAN
NC score	0.012159 (rank : 233)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	351	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

CO4A4_HUMAN
NC score	0.012088 (rank : 234)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	351	Target Neighborhood Hits	440	Shared Neighborhood Hits	47
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

RRBP1_MOUSE
NC score	0.011988 (rank : 235)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	351	Target Neighborhood Hits	1650	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NRG3_MOUSE
NC score	0.011901 (rank : 236)	θ value	6.88961 (rank : 293)
Query Neighborhood Hits	351	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

CO4A5_HUMAN
NC score	0.011758 (rank : 237)	θ value	6.88961 (rank : 277)
Query Neighborhood Hits	351	Target Neighborhood Hits	383	Shared Neighborhood Hits	43
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

KCNH2_MOUSE
NC score	0.011654 (rank : 238)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	351	Target Neighborhood Hits	165	Shared Neighborhood Hits	29
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

CO2A1_MOUSE
NC score	0.011563 (rank : 239)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	351	Target Neighborhood Hits	483	Shared Neighborhood Hits	48
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

TMM24_MOUSE
NC score	0.011426 (rank : 240)	θ value	6.88961 (rank : 301)
Query Neighborhood Hits	351	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

NU133_HUMAN
NC score	0.011279 (rank : 241)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	351	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

RNF12_HUMAN
NC score	0.011266 (rank : 242)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	351	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

NEIL1_MOUSE
NC score	0.011175 (rank : 243)	θ value	3.0926 (rank : 210)
Query Neighborhood Hits	351	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

SYN2_MOUSE
NC score	0.011019 (rank : 244)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	351	Target Neighborhood Hits	183	Shared Neighborhood Hits	29
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

NFAC3_HUMAN
NC score	0.011000 (rank : 245)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	351	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

BRD2_HUMAN
NC score	0.010969 (rank : 246)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	351	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

SOCS7_MOUSE
NC score	0.010937 (rank : 247)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	351	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

BAP1_MOUSE
NC score	0.010888 (rank : 248)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	351	Target Neighborhood Hits	118	Shared Neighborhood Hits	22
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

KTNA1_HUMAN
NC score	0.010860 (rank : 249)	θ value	0.125558 (rank : 79)
Query Neighborhood Hits	351	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

CSKI2_MOUSE
NC score	0.010782 (rank : 250)	θ value	0.279714 (rank : 95)
Query Neighborhood Hits	351	Target Neighborhood Hits	812	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CENG1_MOUSE
NC score	0.010755 (rank : 251)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	351	Target Neighborhood Hits	531	Shared Neighborhood Hits	32
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

FOG1_MOUSE
NC score	0.010735 (rank : 252)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	351	Target Neighborhood Hits	1237	Shared Neighborhood Hits	96
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

TDRD3_HUMAN
NC score	0.010457 (rank : 253)	θ value	4.03905 (rank : 243)
Query Neighborhood Hits	351	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

MUC2_HUMAN
NC score	0.010368 (rank : 254)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	351	Target Neighborhood Hits	906	Shared Neighborhood Hits	63
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CSKI1_MOUSE
NC score	0.010287 (rank : 255)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	351	Target Neighborhood Hits	1031	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TAF3_HUMAN
NC score	0.010285 (rank : 256)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	351	Target Neighborhood Hits	568	Shared Neighborhood Hits	38
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

VASP_MOUSE
NC score	0.009993 (rank : 257)	θ value	6.88961 (rank : 304)
Query Neighborhood Hits	351	Target Neighborhood Hits	195	Shared Neighborhood Hits	23
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPHK2_HUMAN
NC score	0.009939 (rank : 258)	θ value	6.88961 (rank : 297)
Query Neighborhood Hits	351	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

VGF_HUMAN
NC score	0.009870 (rank : 259)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	351	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

A16L1_MOUSE
NC score	0.009797 (rank : 260)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	351	Target Neighborhood Hits	776	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

US6NL_HUMAN
NC score	0.009725 (rank : 261)	θ value	6.88961 (rank : 303)
Query Neighborhood Hits	351	Target Neighborhood Hits	201	Shared Neighborhood Hits	33
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

TRPS1_HUMAN
NC score	0.009632 (rank : 262)	θ value	1.38821 (rank : 156)
Query Neighborhood Hits	351	Target Neighborhood Hits	539	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

TMM24_HUMAN
NC score	0.009620 (rank : 263)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	351	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

RFX1_HUMAN
NC score	0.009582 (rank : 264)	θ value	6.88961 (rank : 294)
Query Neighborhood Hits	351	Target Neighborhood Hits	256	Shared Neighborhood Hits	37
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

KTNA1_MOUSE
NC score	0.009474 (rank : 265)	θ value	0.47712 (rank : 106)
Query Neighborhood Hits	351	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

PCGF2_HUMAN
NC score	0.009460 (rank : 266)	θ value	1.38821 (rank : 151)
Query Neighborhood Hits	351	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

SEM6C_MOUSE
NC score	0.009386 (rank : 267)	θ value	5.27518 (rank : 266)
Query Neighborhood Hits	351	Target Neighborhood Hits	352	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SREC2_HUMAN
NC score	0.009191 (rank : 268)	θ value	0.47712 (rank : 113)
Query Neighborhood Hits	351	Target Neighborhood Hits	645	Shared Neighborhood Hits	44
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SHAN1_HUMAN
NC score	0.008417 (rank : 269)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	351	Target Neighborhood Hits	1041	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PLXB1_HUMAN
NC score	0.008352 (rank : 270)	θ value	1.38821 (rank : 152)
Query Neighborhood Hits	351	Target Neighborhood Hits	360	Shared Neighborhood Hits	41
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

DPOLZ_HUMAN
NC score	0.008207 (rank : 271)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	351	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

INVS_MOUSE
NC score	0.008152 (rank : 272)	θ value	8.99809 (rank : 326)
Query Neighborhood Hits	351	Target Neighborhood Hits	609	Shared Neighborhood Hits	60
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

EMIL2_MOUSE
NC score	0.008096 (rank : 273)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	351	Target Neighborhood Hits	485	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

GBF1_HUMAN
NC score	0.008006 (rank : 274)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	351	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

A16L1_HUMAN
NC score	0.007974 (rank : 275)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	351	Target Neighborhood Hits	664	Shared Neighborhood Hits	27
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

RADI_HUMAN
NC score	0.007968 (rank : 276)	θ value	1.06291 (rank : 140)
Query Neighborhood Hits	351	Target Neighborhood Hits	741	Shared Neighborhood Hits	30
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

K1024_MOUSE
NC score	0.007963 (rank : 277)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	351	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3V7, Q69ZS9	Gene names	Kiaa1024
Domain Architecture
Description	UPF0258 protein KIAA1024 (Protein DD1).

RADI_MOUSE
NC score	0.007960 (rank : 278)	θ value	1.06291 (rank : 141)
Query Neighborhood Hits	351	Target Neighborhood Hits	773	Shared Neighborhood Hits	29
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

LUZP1_MOUSE
NC score	0.007937 (rank : 279)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	351	Target Neighborhood Hits	940	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

AB1IP_HUMAN
NC score	0.007936 (rank : 280)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	351	Target Neighborhood Hits	213	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

MEFV_HUMAN
NC score	0.007620 (rank : 281)	θ value	0.62314 (rank : 120)
Query Neighborhood Hits	351	Target Neighborhood Hits	431	Shared Neighborhood Hits	30
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MPP8_HUMAN
NC score	0.007598 (rank : 282)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	351	Target Neighborhood Hits	948	Shared Neighborhood Hits	40
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

GIT2_MOUSE
NC score	0.007578 (rank : 283)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	351	Target Neighborhood Hits	323	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

TCGAP_MOUSE
NC score	0.007445 (rank : 284)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	351	Target Neighborhood Hits	409	Shared Neighborhood Hits	37
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RFX1_MOUSE
NC score	0.007292 (rank : 285)	θ value	6.88961 (rank : 295)
Query Neighborhood Hits	351	Target Neighborhood Hits	181	Shared Neighborhood Hits	19
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

GATA6_HUMAN
NC score	0.007206 (rank : 286)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	351	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	Q92908, P78327	Gene names	GATA6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

RBM14_MOUSE
NC score	0.007148 (rank : 287)	θ value	8.99809 (rank : 336)
Query Neighborhood Hits	351	Target Neighborhood Hits	217	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

TRPS1_MOUSE
NC score	0.007065 (rank : 288)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	351	Target Neighborhood Hits	609	Shared Neighborhood Hits	21
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

KCNH3_HUMAN
NC score	0.007058 (rank : 289)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	351	Target Neighborhood Hits	148	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

GASP2_MOUSE
NC score	0.007033 (rank : 290)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	351	Target Neighborhood Hits	228	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

ERF_HUMAN
NC score	0.006927 (rank : 291)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	351	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

KCNH3_MOUSE
NC score	0.006896 (rank : 292)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	351	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

EPN2_MOUSE
NC score	0.006861 (rank : 293)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	351	Target Neighborhood Hits	111	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

ZO1_HUMAN
NC score	0.006814 (rank : 294)	θ value	4.03905 (rank : 246)
Query Neighborhood Hits	351	Target Neighborhood Hits	474	Shared Neighborhood Hits	35
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ERF_MOUSE
NC score	0.006772 (rank : 295)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	351	Target Neighborhood Hits	160	Shared Neighborhood Hits	21
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

RIMB1_MOUSE
NC score	0.006605 (rank : 296)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	351	Target Neighborhood Hits	1376	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

DYN3_HUMAN
NC score	0.006594 (rank : 297)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	351	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

K1849_HUMAN
NC score	0.006458 (rank : 298)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	351	Target Neighborhood Hits	220	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

CT116_HUMAN
NC score	0.006454 (rank : 299)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	351	Target Neighborhood Hits	294	Shared Neighborhood Hits	15
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

SOX9_MOUSE
NC score	0.006291 (rank : 300)	θ value	3.0926 (rank : 214)
Query Neighborhood Hits	351	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

DDEF2_HUMAN
NC score	0.006258 (rank : 301)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	351	Target Neighborhood Hits	599	Shared Neighborhood Hits	37
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

B4GT1_HUMAN
NC score	0.005944 (rank : 302)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	351	Target Neighborhood Hits	168	Shared Neighborhood Hits	23
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CDR2_MOUSE
NC score	0.005670 (rank : 303)	θ value	6.88961 (rank : 276)
Query Neighborhood Hits	351	Target Neighborhood Hits	482	Shared Neighborhood Hits	21
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

SPEG_HUMAN
NC score	0.005612 (rank : 304)	θ value	0.47712 (rank : 112)
Query Neighborhood Hits	351	Target Neighborhood Hits	1762	Shared Neighborhood Hits	95
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

NEUL1_HUMAN
NC score	0.005593 (rank : 305)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	351	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

SSH1_MOUSE
NC score	0.005561 (rank : 306)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	351	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

WHRN_MOUSE
NC score	0.005450 (rank : 307)	θ value	5.27518 (rank : 269)
Query Neighborhood Hits	351	Target Neighborhood Hits	412	Shared Neighborhood Hits	27
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WDR67_MOUSE
NC score	0.005404 (rank : 308)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	351	Target Neighborhood Hits	476	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

ZN516_MOUSE
NC score	0.005365 (rank : 309)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	351	Target Neighborhood Hits	1197	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

SPEG_MOUSE
NC score	0.005356 (rank : 310)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	351	Target Neighborhood Hits	1959	Shared Neighborhood Hits	114
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

FOXN1_HUMAN
NC score	0.005320 (rank : 311)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	351	Target Neighborhood Hits	377	Shared Neighborhood Hits	35
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

PUR8_MOUSE
NC score	0.005303 (rank : 312)	θ value	8.99809 (rank : 334)
Query Neighborhood Hits	351	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P54822	Gene names	Adsl, Adl
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

MAST4_HUMAN
NC score	0.005199 (rank : 313)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	351	Target Neighborhood Hits	1804	Shared Neighborhood Hits	113
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SOX7_HUMAN
NC score	0.005143 (rank : 314)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	351	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

ASCC2_HUMAN
NC score	0.005139 (rank : 315)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	351	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1I8, Q4TT54, Q8TAZ0, Q9H711, Q9H9D6	Gene names	ASCC2, ASC1P100
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100).

ROAA_MOUSE
NC score	0.004975 (rank : 316)	θ value	1.38821 (rank : 153)
Query Neighborhood Hits	351	Target Neighborhood Hits	208	Shared Neighborhood Hits	9
SwissProt Accessions	Q99020, Q8BPE0	Gene names	Hnrpab, Cbf-a, Cgbfa
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A).

FBXL6_HUMAN
NC score	0.004933 (rank : 317)	θ value	6.88961 (rank : 282)
Query Neighborhood Hits	351	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

IRX5_HUMAN
NC score	0.004911 (rank : 318)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	351	Target Neighborhood Hits	362	Shared Neighborhood Hits	32
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

RAD9A_HUMAN
NC score	0.004816 (rank : 319)	θ value	8.99809 (rank : 335)
Query Neighborhood Hits	351	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q99638, Q6FI29, Q96C41	Gene names	RAD9A
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A) (hRAD9).

MOES_HUMAN
NC score	0.004769 (rank : 320)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	351	Target Neighborhood Hits	892	Shared Neighborhood Hits	38
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PAXI_MOUSE
NC score	0.004685 (rank : 321)	θ value	0.62314 (rank : 122)
Query Neighborhood Hits	351	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

ERG25_HUMAN
NC score	0.004621 (rank : 322)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	351	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q15800, Q32Q24	Gene names	SC4MOL, DESP4, ERG25
Domain Architecture
Description	C-4 methylsterol oxidase (EC 1.14.13.72) (Methylsterol monooxygenase).

GP149_HUMAN
NC score	0.004564 (rank : 323)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	351	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

GPR75_MOUSE
NC score	0.004423 (rank : 324)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	351	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q6X632, Q3URC1, Q8BXP3	Gene names	Gpr75
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 75.

ITSN1_HUMAN
NC score	0.004176 (rank : 325)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	351	Target Neighborhood Hits	1757	Shared Neighborhood Hits	83
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MACOI_HUMAN
NC score	0.004138 (rank : 326)	θ value	8.99809 (rank : 328)
Query Neighborhood Hits	351	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

RIN1_MOUSE
NC score	0.003853 (rank : 327)	θ value	8.99809 (rank : 337)
Query Neighborhood Hits	351	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

MACOI_MOUSE
NC score	0.003852 (rank : 328)	θ value	8.99809 (rank : 329)
Query Neighborhood Hits	351	Target Neighborhood Hits	620	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

WNK4_MOUSE
NC score	0.003846 (rank : 329)	θ value	0.0193708 (rank : 57)
Query Neighborhood Hits	351	Target Neighborhood Hits	961	Shared Neighborhood Hits	36
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

DMWD_MOUSE
NC score	0.003635 (rank : 330)	θ value	6.88961 (rank : 279)
Query Neighborhood Hits	351	Target Neighborhood Hits	282	Shared Neighborhood Hits	15
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

C1QR1_HUMAN
NC score	0.003428 (rank : 331)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	351	Target Neighborhood Hits	493	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

NKX24_MOUSE
NC score	0.003395 (rank : 332)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	351	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EQM3, Q9EQM4	Gene names	Nkx2-4, Nkx2d
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

ACK1_MOUSE
NC score	0.003097 (rank : 333)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	351	Target Neighborhood Hits	1080	Shared Neighborhood Hits	60
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

BPA1_MOUSE
NC score	0.003015 (rank : 334)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	351	Target Neighborhood Hits	1477	Shared Neighborhood Hits	48
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

NCOA1_HUMAN
NC score	0.002777 (rank : 335)	θ value	8.99809 (rank : 331)
Query Neighborhood Hits	351	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

ITSN2_MOUSE
NC score	0.002586 (rank : 336)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	351	Target Neighborhood Hits	1371	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

FOXE2_HUMAN
NC score	0.002571 (rank : 337)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	351	Target Neighborhood Hits	236	Shared Neighborhood Hits	28
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

ETBR2_HUMAN
NC score	0.002536 (rank : 338)	θ value	6.88961 (rank : 281)
Query Neighborhood Hits	351	Target Neighborhood Hits	489	Shared Neighborhood Hits	5
SwissProt Accessions	O60883, Q86VP7	Gene names	GPR37L1, ETBRLP2
Domain Architecture
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

CP250_HUMAN
NC score	0.002525 (rank : 339)	θ value	6.88961 (rank : 278)
Query Neighborhood Hits	351	Target Neighborhood Hits	1805	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

ANKS6_MOUSE
NC score	0.002235 (rank : 340)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	351	Target Neighborhood Hits	435	Shared Neighborhood Hits	29
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

LTBP4_MOUSE
NC score	0.001796 (rank : 341)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	351	Target Neighborhood Hits	607	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PAK4_MOUSE
NC score	0.001571 (rank : 342)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	351	Target Neighborhood Hits	1098	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

ZEP1_MOUSE
NC score	0.001554 (rank : 343)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	351	Target Neighborhood Hits	1063	Shared Neighborhood Hits	58
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

NR1H3_MOUSE
NC score	0.001539 (rank : 344)	θ value	1.38821 (rank : 150)
Query Neighborhood Hits	351	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

ST2B1_HUMAN
NC score	0.001247 (rank : 345)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	351	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

TBX5_MOUSE
NC score	0.001154 (rank : 346)	θ value	6.88961 (rank : 300)
Query Neighborhood Hits	351	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

ADA29_HUMAN
NC score	0.000565 (rank : 347)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	351	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

MYH4_HUMAN
NC score	0.000366 (rank : 348)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	351	Target Neighborhood Hits	1377	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

ULK1_HUMAN
NC score	0.000346 (rank : 349)	θ value	6.88961 (rank : 302)
Query Neighborhood Hits	351	Target Neighborhood Hits	1121	Shared Neighborhood Hits	58
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

NOTC3_MOUSE
NC score	0.000211 (rank : 350)	θ value	1.81305 (rank : 168)
Query Neighborhood Hits	351	Target Neighborhood Hits	975	Shared Neighborhood Hits	32
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TMPSD_MOUSE
NC score	0.000086 (rank : 351)	θ value	2.36792 (rank : 195)
Query Neighborhood Hits	351	Target Neighborhood Hits	334	Shared Neighborhood Hits	26
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

SALL3_HUMAN
NC score	0.000012 (rank : 352)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	351	Target Neighborhood Hits	1066	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

BMP2_HUMAN
NC score	-0.000057 (rank : 353)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	351	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	P12643	Gene names	BMP2, BMP2A
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

PEG3_MOUSE
NC score	-0.000228 (rank : 354)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	351	Target Neighborhood Hits	1101	Shared Neighborhood Hits	38
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

CTRO_HUMAN
NC score	-0.000281 (rank : 355)	θ value	1.81305 (rank : 163)
Query Neighborhood Hits	351	Target Neighborhood Hits	2092	Shared Neighborhood Hits	67
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

M3K1_MOUSE
NC score	-0.000513 (rank : 356)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	351	Target Neighborhood Hits	952	Shared Neighborhood Hits	31
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

HXA2_MOUSE
NC score	-0.000651 (rank : 357)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	351	Target Neighborhood Hits	338	Shared Neighborhood Hits	11
SwissProt Accessions	P31245, Q149U3, Q920T8	Gene names	Hoxa2, Hox-1.11, Hoxa-2
Domain Architecture
Description	Homeobox protein Hox-A2 (Hox-1.11) (Hox1.11).

HXB4_MOUSE
NC score	-0.001017 (rank : 358)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	351	Target Neighborhood Hits	375	Shared Neighborhood Hits	12
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

M3K6_HUMAN
NC score	-0.001152 (rank : 359)	θ value	1.81305 (rank : 166)
Query Neighborhood Hits	351	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

M3K12_MOUSE
NC score	-0.001562 (rank : 360)	θ value	1.38821 (rank : 148)
Query Neighborhood Hits	351	Target Neighborhood Hits	957	Shared Neighborhood Hits	32
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

TAOK3_HUMAN
NC score	-0.001734 (rank : 361)	θ value	6.88961 (rank : 298)
Query Neighborhood Hits	351	Target Neighborhood Hits	1494	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TAOK3_MOUSE
NC score	-0.001737 (rank : 362)	θ value	6.88961 (rank : 299)
Query Neighborhood Hits	351	Target Neighborhood Hits	1458	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

ATBF1_MOUSE
NC score	-0.001745 (rank : 363)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	351	Target Neighborhood Hits	1841	Shared Neighborhood Hits	78
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PIM2_MOUSE
NC score	-0.001833 (rank : 364)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	351	Target Neighborhood Hits	809	Shared Neighborhood Hits	17
SwissProt Accessions	Q62070, Q62071, Q62072	Gene names	Pim2, Pim-2
Domain Architecture
Description	Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1).

ABL2_HUMAN
NC score	-0.002141 (rank : 365)	θ value	2.36792 (rank : 176)
Query Neighborhood Hits	351	Target Neighborhood Hits	1045	Shared Neighborhood Hits	30
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

BRSK2_HUMAN
NC score	-0.002945 (rank : 366)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	351	Target Neighborhood Hits	897	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

MTF1_MOUSE
NC score	-0.003572 (rank : 367)	θ value	1.81305 (rank : 167)
Query Neighborhood Hits	351	Target Neighborhood Hits	785	Shared Neighborhood Hits	24
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

KLF14_HUMAN
NC score	-0.003617 (rank : 368)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	351	Target Neighborhood Hits	725	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

ZN692_HUMAN
NC score	-0.004196 (rank : 369)	θ value	5.27518 (rank : 270)
Query Neighborhood Hits	351	Target Neighborhood Hits	808	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

ACM4_MOUSE
NC score	-0.005218 (rank : 370)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	351	Target Neighborhood Hits	894	Shared Neighborhood Hits	8
SwissProt Accessions	P32211, Q64056	Gene names	Chrm4, Chrm-4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4 (Mm4 mAChR).

ZBT17_MOUSE
NC score	-0.005541 (rank : 371)	θ value	6.88961 (rank : 305)
Query Neighborhood Hits	351	Target Neighborhood Hits	940	Shared Neighborhood Hits	23
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).