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Network neighborhood for query Sequence : SC11A_MOUSE

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SC11A_MOUSE
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SC10A_HUMAN
θ value	0 (rank : 1)	NC score	0.986145 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SC10A_MOUSE
θ value	0 (rank : 2)	NC score	0.987248 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	107	Shared Neighborhood Hits	75
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC11A_HUMAN
θ value	0 (rank : 3)	NC score	0.994435 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	111	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN1A_HUMAN
θ value	0 (rank : 5)	NC score	0.984738 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	68
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN2A_HUMAN
θ value	0 (rank : 6)	NC score	0.984662 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	157	Shared Neighborhood Hits	67
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN3A_HUMAN
θ value	0 (rank : 7)	NC score	0.987088 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	115	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN4A_HUMAN
θ value	0 (rank : 8)	NC score	0.990556 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	83
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
θ value	0 (rank : 9)	NC score	0.988058 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	145	Shared Neighborhood Hits	71
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN7A_HUMAN
θ value	0 (rank : 10)	NC score	0.984827 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN8A_HUMAN
θ value	0 (rank : 11)	NC score	0.983310 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	0 (rank : 12)	NC score	0.982736 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	136	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN9A_HUMAN
θ value	0 (rank : 13)	NC score	0.984696 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	157	Shared Neighborhood Hits	72
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

CAC1D_HUMAN
θ value	7.93343e-89 (rank : 14)	NC score	0.866604 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	118	Shared Neighborhood Hits	65
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1C_HUMAN
θ value	1.2268e-81 (rank : 15)	NC score	0.854321 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1G_HUMAN
θ value	2.92676e-75 (rank : 16)	NC score	0.866486 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	587	Shared Neighborhood Hits	67
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_MOUSE
θ value	3.82246e-75 (rank : 17)	NC score	0.890917 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	230	Shared Neighborhood Hits	71
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	6.52014e-75 (rank : 18)	NC score	0.909697 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	138	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_HUMAN
θ value	1.11217e-74 (rank : 19)	NC score	0.884099 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	307	Shared Neighborhood Hits	70
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1S_HUMAN
θ value	8.81223e-72 (rank : 20)	NC score	0.864626 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
θ value	3.70236e-70 (rank : 21)	NC score	0.865257 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	98	Shared Neighborhood Hits	61
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1F_MOUSE
θ value	4.52582e-68 (rank : 22)	NC score	0.860857 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	142	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
θ value	1.00825e-67 (rank : 23)	NC score	0.859965 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	141	Shared Neighborhood Hits	64
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1A_MOUSE
θ value	3.83135e-67 (rank : 24)	NC score	0.867576 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1E_HUMAN
θ value	5.53243e-66 (rank : 25)	NC score	0.871562 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	9.43692e-66 (rank : 26)	NC score	0.871853 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	167	Shared Neighborhood Hits	64
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_HUMAN
θ value	3.58603e-65 (rank : 27)	NC score	0.859986 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	387	Shared Neighborhood Hits	74
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
θ value	6.11685e-65 (rank : 28)	NC score	0.862560 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	257	Shared Neighborhood Hits	67
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	5.7252e-63 (rank : 29)	NC score	0.858806 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	351	Shared Neighborhood Hits	69
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_MOUSE
θ value	5.7252e-63 (rank : 30)	NC score	0.857583 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

KCNS2_MOUSE
θ value	1.29631e-06 (rank : 31)	NC score	0.246821 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	130	Shared Neighborhood Hits	67
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
θ value	3.77169e-06 (rank : 32)	NC score	0.241708 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

TRPV3_HUMAN
θ value	0.000121331 (rank : 33)	NC score	0.115735 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	198	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

KCNF1_HUMAN
θ value	0.000786445 (rank : 34)	NC score	0.268316 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCND3_HUMAN
θ value	0.00175202 (rank : 35)	NC score	0.212751 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.00175202 (rank : 36)	NC score	0.212899 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNB2_HUMAN
θ value	0.00228821 (rank : 37)	NC score	0.248746 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

TRPV3_MOUSE
θ value	0.00228821 (rank : 38)	NC score	0.087056 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	188	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

PKDRE_HUMAN
θ value	0.00390308 (rank : 39)	NC score	0.125784 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	64	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNG3_HUMAN
θ value	0.00509761 (rank : 40)	NC score	0.133950 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

PK2L2_HUMAN
θ value	0.00509761 (rank : 41)	NC score	0.316595 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	90	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCNA2_HUMAN
θ value	0.00665767 (rank : 42)	NC score	0.124107 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	101	Shared Neighborhood Hits	46
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	0.00665767 (rank : 43)	NC score	0.124974 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCND1_HUMAN
θ value	0.00665767 (rank : 44)	NC score	0.185867 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	160	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND2_HUMAN
θ value	0.00665767 (rank : 45)	NC score	0.204993 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	154	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.00665767 (rank : 46)	NC score	0.205170 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	156	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNS3_HUMAN
θ value	0.00665767 (rank : 47)	NC score	0.212991 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	125	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNV2_HUMAN
θ value	0.00665767 (rank : 48)	NC score	0.252981 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNG3_MOUSE
θ value	0.00869519 (rank : 49)	NC score	0.134002 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

TRPV4_MOUSE
θ value	0.00869519 (rank : 50)	NC score	0.084254 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_HUMAN
θ value	0.0113563 (rank : 51)	NC score	0.082449 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	150	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

PK2L2_MOUSE
θ value	0.0193708 (rank : 52)	NC score	0.279146 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCNA5_MOUSE
θ value	0.0252991 (rank : 53)	NC score	0.117519 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	119	Shared Neighborhood Hits	46
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNB1_HUMAN
θ value	0.0330416 (rank : 54)	NC score	0.229663 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	169	Shared Neighborhood Hits	66
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0.0330416 (rank : 55)	NC score	0.229711 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	154	Shared Neighborhood Hits	66
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

PKD2_HUMAN
θ value	0.0330416 (rank : 56)	NC score	0.270145 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	48
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNC3_MOUSE
θ value	0.0563607 (rank : 57)	NC score	0.153071 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	173	Shared Neighborhood Hits	60
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCND1_MOUSE
θ value	0.0563607 (rank : 58)	NC score	0.186996 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

PK2L1_HUMAN
θ value	0.0563607 (rank : 59)	NC score	0.292135 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

KCNC3_HUMAN
θ value	0.0736092 (rank : 60)	NC score	0.154964 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	256	Shared Neighborhood Hits	61
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNQ5_HUMAN
θ value	0.0736092 (rank : 61)	NC score	0.088400 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	163	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNA5_HUMAN
θ value	0.0961366 (rank : 62)	NC score	0.111709 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNC4_HUMAN
θ value	0.0961366 (rank : 63)	NC score	0.162756 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC1_HUMAN
θ value	0.125558 (rank : 64)	NC score	0.179140 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	62
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

CABP5_MOUSE
θ value	0.163984 (rank : 65)	NC score	0.055694 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

KCNC1_MOUSE
θ value	0.163984 (rank : 66)	NC score	0.176876 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	62
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNQ4_HUMAN
θ value	0.163984 (rank : 67)	NC score	0.107727 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	136	Shared Neighborhood Hits	48
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNS1_HUMAN
θ value	0.163984 (rank : 68)	NC score	0.179287 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	65
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

MCLN2_HUMAN
θ value	0.163984 (rank : 69)	NC score	0.041274 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

KCNA3_HUMAN
θ value	0.279714 (rank : 70)	NC score	0.115342 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNC4_MOUSE
θ value	0.279714 (rank : 71)	NC score	0.155453 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNA1_HUMAN
θ value	0.365318 (rank : 72)	NC score	0.124370 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	104	Shared Neighborhood Hits	49
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	0.365318 (rank : 73)	NC score	0.125831 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA3_MOUSE
θ value	0.365318 (rank : 74)	NC score	0.114508 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

TPTE2_HUMAN
θ value	0.365318 (rank : 75)	NC score	0.141193 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

TRPC2_MOUSE
θ value	0.365318 (rank : 76)	NC score	0.021812 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

KCNA6_HUMAN
θ value	0.62314 (rank : 77)	NC score	0.117516 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	0.62314 (rank : 78)	NC score	0.120064 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

PKD2_MOUSE
θ value	0.813845 (rank : 79)	NC score	0.273335 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	46
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

HCN3_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.007015 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.007021 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

IF2P_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.005999 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	889	Shared Neighborhood Hits	6
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

TRPC1_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.067388 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	91	Shared Neighborhood Hits	22
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.067494 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPV1_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.059109 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	184	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.048511 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

CABP5_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.039280 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

KCNS1_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.161262 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

CF081_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.010287 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T9G4, Q8NEB2, Q96LL8	Gene names	C6orf81
Domain Architecture	No domain graphic available
Description	Protein C6orf81.

GOGA3_MOUSE
θ value	3.0926 (rank : 90)	NC score	-0.003813 (rank : 127)
Query Neighborhood Hits	116	Target Neighborhood Hits	1437	Shared Neighborhood Hits	4
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

ITPR1_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.016570 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.016532 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

ITPR2_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.012672 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

RYR3_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.011811 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

TBC14_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.008186 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGA2, Q8CHA5	Gene names	Tbc1d14, D5Ertd110e, Kiaa1322
Domain Architecture
Description	TBC1 domain family member 14.

TRPM8_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.044869 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TPTE_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.096314 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TRPM8_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.038558 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

AXN2_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.005212 (rank : 118)
Query Neighborhood Hits	116	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

CDC27_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.005056 (rank : 119)
Query Neighborhood Hits	116	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

ITPR2_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.012083 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

RYR2_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.010951 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

TBC14_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.007226 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

EI2BD_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.005520 (rank : 117)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

PCLO_MOUSE
θ value	6.88961 (rank : 105)	NC score	-0.000245 (rank : 125)
Query Neighborhood Hits	116	Target Neighborhood Hits	2275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PKDRE_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.094477 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

REN3B_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.001739 (rank : 122)
Query Neighborhood Hits	116	Target Neighborhood Hits	412	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

AIM2_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.003931 (rank : 120)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

CBPA3_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.001669 (rank : 123)
Query Neighborhood Hits	116	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P15088, Q96E94	Gene names	CPA3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

CNTN5_HUMAN
θ value	8.99809 (rank : 110)	NC score	-0.002326 (rank : 126)
Query Neighborhood Hits	116	Target Neighborhood Hits	446	Shared Neighborhood Hits	2
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

MCLN2_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.051605 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MCLN3_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.030862 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4F0, Q8BS73, Q8BSG1, Q8CDB2	Gene names	Mcoln3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

PK1L1_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.029833 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

RGMC_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.003428 (rank : 121)
Query Neighborhood Hits	116	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZVN8, Q2PQ63, Q6IMF6, Q8NAH2, Q8WVJ5	Gene names	HFE2, HJV, RGMC
Domain Architecture	No domain graphic available
Description	Hemojuvelin precursor (Hemochromatosis type 2 protein) (RGM domain family member C).

SAMD9_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.005652 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q5K651, Q6P080, Q75N21, Q8IVG6, Q9NXS8	Gene names	SAMD9, KIAA2004, OEF1
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 9.

UBP18_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.001494 (rank : 124)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

KCNA4_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.097964 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	108	Shared Neighborhood Hits	38
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.098557 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNG1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.105265 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	103	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.098750 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.098248 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.089163 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.097271 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	175	Shared Neighborhood Hits	47
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.075308 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	114	Shared Neighborhood Hits	41
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.072412 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.073061 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.072467 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

Hits sorted by NC score

SC11A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.994435 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	111	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN4A_HUMAN
NC score	0.990556 (rank : 3)	θ value	0 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	83
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
NC score	0.988058 (rank : 4)	θ value	0 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	145	Shared Neighborhood Hits	71
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SC10A_MOUSE
NC score	0.987248 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	107	Shared Neighborhood Hits	75
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN3A_HUMAN
NC score	0.987088 (rank : 6)	θ value	0 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	115	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SC10A_HUMAN
NC score	0.986145 (rank : 7)	θ value	0 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN7A_HUMAN
NC score	0.984827 (rank : 8)	θ value	0 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN1A_HUMAN
NC score	0.984738 (rank : 9)	θ value	0 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	68
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN9A_HUMAN
NC score	0.984696 (rank : 10)	θ value	0 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	157	Shared Neighborhood Hits	72
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN2A_HUMAN
NC score	0.984662 (rank : 11)	θ value	0 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	157	Shared Neighborhood Hits	67
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN8A_HUMAN
NC score	0.983310 (rank : 12)	θ value	0 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
NC score	0.982736 (rank : 13)	θ value	0 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	136	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1I_HUMAN
NC score	0.909697 (rank : 14)	θ value	6.52014e-75 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	138	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.890917 (rank : 15)	θ value	3.82246e-75 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	230	Shared Neighborhood Hits	71
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.884099 (rank : 16)	θ value	1.11217e-74 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	307	Shared Neighborhood Hits	70
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1E_MOUSE
NC score	0.871853 (rank : 17)	θ value	9.43692e-66 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	167	Shared Neighborhood Hits	64
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.871562 (rank : 18)	θ value	5.53243e-66 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_MOUSE
NC score	0.867576 (rank : 19)	θ value	3.83135e-67 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1D_HUMAN
NC score	0.866604 (rank : 20)	θ value	7.93343e-89 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	118	Shared Neighborhood Hits	65
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1G_HUMAN
NC score	0.866486 (rank : 21)	θ value	2.92676e-75 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	587	Shared Neighborhood Hits	67
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1S_MOUSE
NC score	0.865257 (rank : 22)	θ value	3.70236e-70 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	98	Shared Neighborhood Hits	61
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_HUMAN
NC score	0.864626 (rank : 23)	θ value	8.81223e-72 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1B_HUMAN
NC score	0.862560 (rank : 24)	θ value	6.11685e-65 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	257	Shared Neighborhood Hits	67
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_MOUSE
NC score	0.860857 (rank : 25)	θ value	4.52582e-68 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	142	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1A_HUMAN
NC score	0.859986 (rank : 26)	θ value	3.58603e-65 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	387	Shared Neighborhood Hits	74
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1F_HUMAN
NC score	0.859965 (rank : 27)	θ value	1.00825e-67 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	141	Shared Neighborhood Hits	64
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1B_MOUSE
NC score	0.858806 (rank : 28)	θ value	5.7252e-63 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	351	Shared Neighborhood Hits	69
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_MOUSE
NC score	0.857583 (rank : 29)	θ value	5.7252e-63 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.854321 (rank : 30)	θ value	1.2268e-81 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

PK2L2_HUMAN
NC score	0.316595 (rank : 31)	θ value	0.00509761 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	90	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.292135 (rank : 32)	θ value	0.0563607 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.279146 (rank : 33)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.273335 (rank : 34)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	46
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.270145 (rank : 35)	θ value	0.0330416 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	48
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.268316 (rank : 36)	θ value	0.000786445 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.252981 (rank : 37)	θ value	0.00665767 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
NC score	0.248746 (rank : 38)	θ value	0.00228821 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.246821 (rank : 39)	θ value	1.29631e-06 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	130	Shared Neighborhood Hits	67
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.241708 (rank : 40)	θ value	3.77169e-06 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_MOUSE
NC score	0.229711 (rank : 41)	θ value	0.0330416 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	154	Shared Neighborhood Hits	66
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.229663 (rank : 42)	θ value	0.0330416 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	169	Shared Neighborhood Hits	66
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNS3_HUMAN
NC score	0.212991 (rank : 43)	θ value	0.00665767 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	125	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND3_MOUSE
NC score	0.212899 (rank : 44)	θ value	0.00175202 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.212751 (rank : 45)	θ value	0.00175202 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND2_MOUSE
NC score	0.205170 (rank : 46)	θ value	0.00665767 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	156	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.204993 (rank : 47)	θ value	0.00665767 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	154	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.186996 (rank : 48)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.185867 (rank : 49)	θ value	0.00665767 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	160	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS1_HUMAN
NC score	0.179287 (rank : 50)	θ value	0.163984 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	65
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.179140 (rank : 51)	θ value	0.125558 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	62
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.176876 (rank : 52)	θ value	0.163984 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	62
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.162756 (rank : 53)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNS1_MOUSE
NC score	0.161262 (rank : 54)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC4_MOUSE
NC score	0.155453 (rank : 55)	θ value	0.279714 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.154964 (rank : 56)	θ value	0.0736092 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	256	Shared Neighborhood Hits	61
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.153071 (rank : 57)	θ value	0.0563607 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	173	Shared Neighborhood Hits	60
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

TPTE2_HUMAN
NC score	0.141193 (rank : 58)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNG3_MOUSE
NC score	0.134002 (rank : 59)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_HUMAN
NC score	0.133950 (rank : 60)	θ value	0.00509761 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNA1_MOUSE
NC score	0.125831 (rank : 61)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

PKDRE_HUMAN
NC score	0.125784 (rank : 62)	θ value	0.00390308 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	64	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNA2_MOUSE
NC score	0.124974 (rank : 63)	θ value	0.00665767 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA1_HUMAN
NC score	0.124370 (rank : 64)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	104	Shared Neighborhood Hits	49
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA2_HUMAN
NC score	0.124107 (rank : 65)	θ value	0.00665767 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	101	Shared Neighborhood Hits	46
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA6_MOUSE
NC score	0.120064 (rank : 66)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA5_MOUSE
NC score	0.117519 (rank : 67)	θ value	0.0252991 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	119	Shared Neighborhood Hits	46
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_HUMAN
NC score	0.117516 (rank : 68)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

TRPV3_HUMAN
NC score	0.115735 (rank : 69)	θ value	0.000121331 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	198	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

KCNA3_HUMAN
NC score	0.115342 (rank : 70)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
NC score	0.114508 (rank : 71)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA5_HUMAN
NC score	0.111709 (rank : 72)	θ value	0.0961366 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNQ4_HUMAN
NC score	0.107727 (rank : 73)	θ value	0.163984 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	136	Shared Neighborhood Hits	48
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNG1_HUMAN
NC score	0.105265 (rank : 74)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	116	Target Neighborhood Hits	103	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
NC score	0.098750 (rank : 75)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	116	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNA4_MOUSE
NC score	0.098557 (rank : 76)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	116	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNG4_HUMAN
NC score	0.098248 (rank : 77)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNA4_HUMAN
NC score	0.097964 (rank : 78)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	116	Target Neighborhood Hits	108	Shared Neighborhood Hits	38
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ1_MOUSE
NC score	0.097271 (rank : 79)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	116	Target Neighborhood Hits	175	Shared Neighborhood Hits	47
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

TPTE_HUMAN
NC score	0.096314 (rank : 80)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

PKDRE_MOUSE
NC score	0.094477 (rank : 81)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNQ1_HUMAN
NC score	0.089163 (rank : 82)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ5_HUMAN
NC score	0.088400 (rank : 83)	θ value	0.0736092 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	163	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TRPV3_MOUSE
NC score	0.087056 (rank : 84)	θ value	0.00228821 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	188	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_MOUSE
NC score	0.084254 (rank : 85)	θ value	0.00869519 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_HUMAN
NC score	0.082449 (rank : 86)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	150	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

KCNQ2_HUMAN
NC score	0.075308 (rank : 87)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	116	Target Neighborhood Hits	114	Shared Neighborhood Hits	41
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
NC score	0.073061 (rank : 88)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	116	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
NC score	0.072467 (rank : 89)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_MOUSE
NC score	0.072412 (rank : 90)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	116	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

TRPC1_MOUSE
NC score	0.067494 (rank : 91)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.067388 (rank : 92)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	91	Shared Neighborhood Hits	22
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPV1_HUMAN
NC score	0.059109 (rank : 93)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	184	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

CABP5_MOUSE
NC score	0.055694 (rank : 94)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

MCLN2_MOUSE
NC score	0.051605 (rank : 95)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

TRPV1_MOUSE
NC score	0.048511 (rank : 96)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPM8_MOUSE
NC score	0.044869 (rank : 97)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

MCLN2_HUMAN
NC score	0.041274 (rank : 98)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

CABP5_HUMAN
NC score	0.039280 (rank : 99)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

TRPM8_HUMAN
NC score	0.038558 (rank : 100)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

MCLN3_MOUSE
NC score	0.030862 (rank : 101)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4F0, Q8BS73, Q8BSG1, Q8CDB2	Gene names	Mcoln3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

PK1L1_HUMAN
NC score	0.029833 (rank : 102)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

TRPC2_MOUSE
NC score	0.021812 (rank : 103)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

ITPR1_HUMAN
NC score	0.016570 (rank : 104)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
NC score	0.016532 (rank : 105)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

ITPR2_MOUSE
NC score	0.012672 (rank : 106)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

ITPR2_HUMAN
NC score	0.012083 (rank : 107)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

RYR3_HUMAN
NC score	0.011811 (rank : 108)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

RYR2_HUMAN
NC score	0.010951 (rank : 109)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

CF081_HUMAN
NC score	0.010287 (rank : 110)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T9G4, Q8NEB2, Q96LL8	Gene names	C6orf81
Domain Architecture	No domain graphic available
Description	Protein C6orf81.

TBC14_MOUSE
NC score	0.008186 (rank : 111)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGA2, Q8CHA5	Gene names	Tbc1d14, D5Ertd110e, Kiaa1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC14_HUMAN
NC score	0.007226 (rank : 112)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

HCN3_MOUSE
NC score	0.007021 (rank : 113)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.007015 (rank : 114)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

IF2P_HUMAN
NC score	0.005999 (rank : 115)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	889	Shared Neighborhood Hits	6
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

SAMD9_HUMAN
NC score	0.005652 (rank : 116)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q5K651, Q6P080, Q75N21, Q8IVG6, Q9NXS8	Gene names	SAMD9, KIAA2004, OEF1
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 9.

EI2BD_HUMAN
NC score	0.005520 (rank : 117)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

AXN2_HUMAN
NC score	0.005212 (rank : 118)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

CDC27_HUMAN
NC score	0.005056 (rank : 119)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

AIM2_HUMAN
NC score	0.003931 (rank : 120)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

RGMC_HUMAN
NC score	0.003428 (rank : 121)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZVN8, Q2PQ63, Q6IMF6, Q8NAH2, Q8WVJ5	Gene names	HFE2, HJV, RGMC
Domain Architecture	No domain graphic available
Description	Hemojuvelin precursor (Hemochromatosis type 2 protein) (RGM domain family member C).

REN3B_HUMAN
NC score	0.001739 (rank : 122)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	412	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

CBPA3_HUMAN
NC score	0.001669 (rank : 123)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P15088, Q96E94	Gene names	CPA3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

UBP18_MOUSE
NC score	0.001494 (rank : 124)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

PCLO_MOUSE
NC score	-0.000245 (rank : 125)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	2275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CNTN5_HUMAN
NC score	-0.002326 (rank : 126)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	446	Shared Neighborhood Hits	2
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

GOGA3_MOUSE
NC score	-0.003813 (rank : 127)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	1437	Shared Neighborhood Hits	4
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).