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Network neighborhood for query Sequence : CAC1H_MOUSE

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CAC1H_MOUSE
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1G_HUMAN
θ value	0 (rank : 1)	NC score	0.955236 (rank : 4)
Query Neighborhood Hits	230	Target Neighborhood Hits	587	Shared Neighborhood Hits	105
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_HUMAN
θ value	0 (rank : 2)	NC score	0.984657 (rank : 2)
Query Neighborhood Hits	230	Target Neighborhood Hits	307	Shared Neighborhood Hits	105
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1H_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	230	Target Neighborhood Hits	230	Shared Neighborhood Hits	230
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	0 (rank : 4)	NC score	0.983744 (rank : 3)
Query Neighborhood Hits	230	Target Neighborhood Hits	138	Shared Neighborhood Hits	76
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SC11A_HUMAN
θ value	3.11973e-85 (rank : 5)	NC score	0.892836 (rank : 5)
Query Neighborhood Hits	230	Target Neighborhood Hits	111	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
θ value	3.82246e-75 (rank : 6)	NC score	0.890917 (rank : 6)
Query Neighborhood Hits	230	Target Neighborhood Hits	116	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN4A_HUMAN
θ value	3.82246e-75 (rank : 7)	NC score	0.884121 (rank : 7)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	70
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SC10A_HUMAN
θ value	2.47765e-74 (rank : 8)	NC score	0.870888 (rank : 24)
Query Neighborhood Hits	230	Target Neighborhood Hits	116	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN2A_HUMAN
θ value	2.73936e-73 (rank : 9)	NC score	0.873070 (rank : 18)
Query Neighborhood Hits	230	Target Neighborhood Hits	157	Shared Neighborhood Hits	58
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN3A_HUMAN
θ value	2.73936e-73 (rank : 10)	NC score	0.877256 (rank : 12)
Query Neighborhood Hits	230	Target Neighborhood Hits	115	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN9A_HUMAN
θ value	6.7473e-72 (rank : 11)	NC score	0.872989 (rank : 19)
Query Neighborhood Hits	230	Target Neighborhood Hits	157	Shared Neighborhood Hits	63
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

CAC1D_HUMAN
θ value	7.45998e-71 (rank : 12)	NC score	0.876504 (rank : 13)
Query Neighborhood Hits	230	Target Neighborhood Hits	118	Shared Neighborhood Hits	64
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

SCN1A_HUMAN
θ value	1.66191e-70 (rank : 13)	NC score	0.872736 (rank : 20)
Query Neighborhood Hits	230	Target Neighborhood Hits	148	Shared Neighborhood Hits	61
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1S_MOUSE
θ value	8.24801e-70 (rank : 14)	NC score	0.877533 (rank : 11)
Query Neighborhood Hits	230	Target Neighborhood Hits	98	Shared Neighborhood Hits	64
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1E_HUMAN
θ value	1.5555e-68 (rank : 15)	NC score	0.881609 (rank : 9)
Query Neighborhood Hits	230	Target Neighborhood Hits	148	Shared Neighborhood Hits	62
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	2.65329e-68 (rank : 16)	NC score	0.881842 (rank : 8)
Query Neighborhood Hits	230	Target Neighborhood Hits	167	Shared Neighborhood Hits	63
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1B_MOUSE
θ value	1.31681e-67 (rank : 17)	NC score	0.871780 (rank : 22)
Query Neighborhood Hits	230	Target Neighborhood Hits	351	Shared Neighborhood Hits	93
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1S_HUMAN
θ value	2.4834e-66 (rank : 18)	NC score	0.875917 (rank : 15)
Query Neighborhood Hits	230	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1F_HUMAN
θ value	3.58603e-65 (rank : 19)	NC score	0.870875 (rank : 25)
Query Neighborhood Hits	230	Target Neighborhood Hits	141	Shared Neighborhood Hits	65
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

SCN8A_HUMAN
θ value	7.98882e-65 (rank : 20)	NC score	0.871373 (rank : 23)
Query Neighborhood Hits	230	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1B_HUMAN
θ value	1.77973e-64 (rank : 21)	NC score	0.873759 (rank : 17)
Query Neighborhood Hits	230	Target Neighborhood Hits	257	Shared Neighborhood Hits	77
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_HUMAN
θ value	3.96481e-64 (rank : 22)	NC score	0.869745 (rank : 27)
Query Neighborhood Hits	230	Target Neighborhood Hits	387	Shared Neighborhood Hits	92
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SCN5A_HUMAN
θ value	3.96481e-64 (rank : 23)	NC score	0.880581 (rank : 10)
Query Neighborhood Hits	230	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN8A_MOUSE
θ value	3.96481e-64 (rank : 24)	NC score	0.869092 (rank : 28)
Query Neighborhood Hits	230	Target Neighborhood Hits	136	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1C_MOUSE
θ value	6.76295e-64 (rank : 25)	NC score	0.868803 (rank : 29)
Query Neighborhood Hits	230	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1F_MOUSE
θ value	8.83269e-64 (rank : 26)	NC score	0.870556 (rank : 26)
Query Neighborhood Hits	230	Target Neighborhood Hits	142	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1A_MOUSE
θ value	7.47731e-63 (rank : 27)	NC score	0.875810 (rank : 16)
Query Neighborhood Hits	230	Target Neighborhood Hits	267	Shared Neighborhood Hits	84
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SC10A_MOUSE
θ value	3.71096e-62 (rank : 28)	NC score	0.872261 (rank : 21)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	64
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN7A_HUMAN
θ value	1.7238e-59 (rank : 29)	NC score	0.876186 (rank : 14)
Query Neighborhood Hits	230	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1C_HUMAN
θ value	7.24236e-58 (rank : 30)	NC score	0.862526 (rank : 30)
Query Neighborhood Hits	230	Target Neighborhood Hits	158	Shared Neighborhood Hits	60
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

KCNB1_HUMAN
θ value	7.59969e-07 (rank : 31)	NC score	0.246281 (rank : 40)
Query Neighborhood Hits	230	Target Neighborhood Hits	169	Shared Neighborhood Hits	66
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	7.59969e-07 (rank : 32)	NC score	0.246265 (rank : 41)
Query Neighborhood Hits	230	Target Neighborhood Hits	154	Shared Neighborhood Hits	65
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNS2_MOUSE
θ value	4.92598e-06 (rank : 33)	NC score	0.254430 (rank : 36)
Query Neighborhood Hits	230	Target Neighborhood Hits	130	Shared Neighborhood Hits	66
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
θ value	6.43352e-06 (rank : 34)	NC score	0.249963 (rank : 38)
Query Neighborhood Hits	230	Target Neighborhood Hits	129	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNV2_HUMAN
θ value	1.09739e-05 (rank : 35)	NC score	0.271886 (rank : 32)
Query Neighborhood Hits	230	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
θ value	1.43324e-05 (rank : 36)	NC score	0.256258 (rank : 35)
Query Neighborhood Hits	230	Target Neighborhood Hits	212	Shared Neighborhood Hits	69
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS1_MOUSE
θ value	4.1701e-05 (rank : 37)	NC score	0.187031 (rank : 50)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS1_HUMAN
θ value	9.29e-05 (rank : 38)	NC score	0.197969 (rank : 48)
Query Neighborhood Hits	230	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

TPTE2_HUMAN
θ value	9.29e-05 (rank : 39)	NC score	0.192249 (rank : 49)
Query Neighborhood Hits	230	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNC1_MOUSE
θ value	0.00134147 (rank : 40)	NC score	0.184157 (rank : 52)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_HUMAN
θ value	0.00175202 (rank : 41)	NC score	0.185490 (rank : 51)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNS3_HUMAN
θ value	0.00390308 (rank : 42)	NC score	0.218959 (rank : 43)
Query Neighborhood Hits	230	Target Neighborhood Hits	125	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

TPTE_HUMAN
θ value	0.00390308 (rank : 43)	NC score	0.141722 (rank : 59)
Query Neighborhood Hits	230	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCND2_MOUSE
θ value	0.0113563 (rank : 44)	NC score	0.201674 (rank : 46)
Query Neighborhood Hits	230	Target Neighborhood Hits	156	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
θ value	0.0148317 (rank : 45)	NC score	0.201228 (rank : 47)
Query Neighborhood Hits	230	Target Neighborhood Hits	154	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

BRCA1_MOUSE
θ value	0.0252991 (rank : 46)	NC score	0.025743 (rank : 112)
Query Neighborhood Hits	230	Target Neighborhood Hits	436	Shared Neighborhood Hits	16
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

KCNF1_HUMAN
θ value	0.0252991 (rank : 47)	NC score	0.266847 (rank : 34)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNC3_HUMAN
θ value	0.0563607 (rank : 48)	NC score	0.158095 (rank : 56)
Query Neighborhood Hits	230	Target Neighborhood Hits	256	Shared Neighborhood Hits	72
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	0.0961366 (rank : 49)	NC score	0.155417 (rank : 58)
Query Neighborhood Hits	230	Target Neighborhood Hits	173	Shared Neighborhood Hits	63
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC4_HUMAN
θ value	0.0961366 (rank : 50)	NC score	0.168930 (rank : 55)
Query Neighborhood Hits	230	Target Neighborhood Hits	141	Shared Neighborhood Hits	60
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

PRRT3_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.030871 (rank : 102)
Query Neighborhood Hits	230	Target Neighborhood Hits	998	Shared Neighborhood Hits	84
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RGS6_HUMAN
θ value	0.163984 (rank : 52)	NC score	0.012289 (rank : 156)
Query Neighborhood Hits	230	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

TARA_MOUSE
θ value	0.163984 (rank : 53)	NC score	0.023027 (rank : 120)
Query Neighborhood Hits	230	Target Neighborhood Hits	1133	Shared Neighborhood Hits	58
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

KCNQ1_HUMAN
θ value	0.21417 (rank : 54)	NC score	0.093499 (rank : 77)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

PK2L1_HUMAN
θ value	0.21417 (rank : 55)	NC score	0.269835 (rank : 33)
Query Neighborhood Hits	230	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PP4R1_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.020760 (rank : 130)
Query Neighborhood Hits	230	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

SPEG_MOUSE
θ value	0.21417 (rank : 57)	NC score	0.005199 (rank : 200)
Query Neighborhood Hits	230	Target Neighborhood Hits	1959	Shared Neighborhood Hits	83
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SSH2_MOUSE
θ value	0.21417 (rank : 58)	NC score	0.011899 (rank : 157)
Query Neighborhood Hits	230	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

PAK4_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.002269 (rank : 223)
Query Neighborhood Hits	230	Target Neighborhood Hits	1098	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

CJ078_MOUSE
θ value	0.365318 (rank : 60)	NC score	0.027177 (rank : 109)
Query Neighborhood Hits	230	Target Neighborhood Hits	559	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

GGN_MOUSE
θ value	0.365318 (rank : 61)	NC score	0.041568 (rank : 93)
Query Neighborhood Hits	230	Target Neighborhood Hits	311	Shared Neighborhood Hits	31
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SOS1_MOUSE
θ value	0.365318 (rank : 62)	NC score	0.013806 (rank : 152)
Query Neighborhood Hits	230	Target Neighborhood Hits	281	Shared Neighborhood Hits	14
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

KCND3_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.202791 (rank : 45)
Query Neighborhood Hits	230	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.47712 (rank : 64)	NC score	0.202974 (rank : 44)
Query Neighborhood Hits	230	Target Neighborhood Hits	162	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNQ1_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.104275 (rank : 72)
Query Neighborhood Hits	230	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

M3K11_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.003264 (rank : 217)
Query Neighborhood Hits	230	Target Neighborhood Hits	1136	Shared Neighborhood Hits	32
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

S36A1_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.039380 (rank : 94)
Query Neighborhood Hits	230	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4D3, Q811N9	Gene names	Slc36a1, Pat1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

SF3B4_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.021653 (rank : 126)
Query Neighborhood Hits	230	Target Neighborhood Hits	445	Shared Neighborhood Hits	29
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

ATS4_MOUSE
θ value	0.62314 (rank : 69)	NC score	0.005077 (rank : 202)
Query Neighborhood Hits	230	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

HIC1_HUMAN
θ value	0.62314 (rank : 70)	NC score	-0.000786 (rank : 235)
Query Neighborhood Hits	230	Target Neighborhood Hits	838	Shared Neighborhood Hits	15
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

K0586_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.019841 (rank : 132)
Query Neighborhood Hits	230	Target Neighborhood Hits	311	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

MKL1_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.021473 (rank : 129)
Query Neighborhood Hits	230	Target Neighborhood Hits	232	Shared Neighborhood Hits	17
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

SAFB2_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.010650 (rank : 164)
Query Neighborhood Hits	230	Target Neighborhood Hits	581	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

TCOF_MOUSE
θ value	0.62314 (rank : 74)	NC score	0.025249 (rank : 115)
Query Neighborhood Hits	230	Target Neighborhood Hits	471	Shared Neighborhood Hits	37
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ASTL_HUMAN
θ value	0.813845 (rank : 75)	NC score	0.021563 (rank : 127)
Query Neighborhood Hits	230	Target Neighborhood Hits	252	Shared Neighborhood Hits	29
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

MUCDL_HUMAN
θ value	0.813845 (rank : 76)	NC score	0.014246 (rank : 149)
Query Neighborhood Hits	230	Target Neighborhood Hits	777	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PLXB1_HUMAN
θ value	0.813845 (rank : 77)	NC score	0.009626 (rank : 171)
Query Neighborhood Hits	230	Target Neighborhood Hits	360	Shared Neighborhood Hits	29
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

TLE1_MOUSE
θ value	0.813845 (rank : 78)	NC score	0.005975 (rank : 193)
Query Neighborhood Hits	230	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TMED8_HUMAN
θ value	0.813845 (rank : 79)	NC score	0.021901 (rank : 124)
Query Neighborhood Hits	230	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PL24, Q9P1V9	Gene names	TMED8
Domain Architecture	No domain graphic available
Description	Protein TMED8.

TOIP2_MOUSE
θ value	0.813845 (rank : 80)	NC score	0.028880 (rank : 105)
Query Neighborhood Hits	230	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

CAF1A_MOUSE
θ value	1.06291 (rank : 81)	NC score	0.006778 (rank : 191)
Query Neighborhood Hits	230	Target Neighborhood Hits	736	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CSKI2_HUMAN
θ value	1.06291 (rank : 82)	NC score	0.011075 (rank : 160)
Query Neighborhood Hits	230	Target Neighborhood Hits	747	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FOG1_HUMAN
θ value	1.06291 (rank : 83)	NC score	0.007741 (rank : 184)
Query Neighborhood Hits	230	Target Neighborhood Hits	981	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IRS2_HUMAN
θ value	1.06291 (rank : 84)	NC score	0.025546 (rank : 113)
Query Neighborhood Hits	230	Target Neighborhood Hits	262	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

KCNA1_MOUSE
θ value	1.06291 (rank : 85)	NC score	0.120904 (rank : 62)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNG3_HUMAN
θ value	1.06291 (rank : 86)	NC score	0.140577 (rank : 60)
Query Neighborhood Hits	230	Target Neighborhood Hits	91	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

PKD2_MOUSE
θ value	1.06291 (rank : 87)	NC score	0.248246 (rank : 39)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

COHA1_MOUSE
θ value	1.38821 (rank : 88)	NC score	0.017662 (rank : 138)
Query Neighborhood Hits	230	Target Neighborhood Hits	414	Shared Neighborhood Hits	25
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

FOXGA_HUMAN
θ value	1.38821 (rank : 89)	NC score	0.007676 (rank : 187)
Query Neighborhood Hits	230	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

KCNK4_MOUSE
θ value	1.38821 (rank : 90)	NC score	0.017882 (rank : 137)
Query Neighborhood Hits	230	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

SON_HUMAN
θ value	1.38821 (rank : 91)	NC score	0.014758 (rank : 146)
Query Neighborhood Hits	230	Target Neighborhood Hits	1568	Shared Neighborhood Hits	83
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TERF2_MOUSE
θ value	1.38821 (rank : 92)	NC score	0.016040 (rank : 140)
Query Neighborhood Hits	230	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TNKS1_HUMAN
θ value	1.38821 (rank : 93)	NC score	0.004877 (rank : 205)
Query Neighborhood Hits	230	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

UN119_HUMAN
θ value	1.38821 (rank : 94)	NC score	0.018944 (rank : 135)
Query Neighborhood Hits	230	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q13432, O95126	Gene names	UNC119, RG4
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (HRG4).

BCAS1_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.015120 (rank : 145)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

CQ050_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.023381 (rank : 119)
Query Neighborhood Hits	230	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WW18, Q6Q621	Gene names	C17orf50
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf50.

DPOLZ_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.010195 (rank : 168)
Query Neighborhood Hits	230	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

KCNA1_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.118532 (rank : 63)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	47
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

M3K15_HUMAN
θ value	1.81305 (rank : 99)	NC score	0.001170 (rank : 225)
Query Neighborhood Hits	230	Target Neighborhood Hits	914	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

NCOR2_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.029069 (rank : 104)
Query Neighborhood Hits	230	Target Neighborhood Hits	870	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR2_MOUSE
θ value	1.81305 (rank : 101)	NC score	0.015884 (rank : 141)
Query Neighborhood Hits	230	Target Neighborhood Hits	790	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

REXO1_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.024839 (rank : 116)
Query Neighborhood Hits	230	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

YLPM1_MOUSE
θ value	1.81305 (rank : 103)	NC score	0.034312 (rank : 97)
Query Neighborhood Hits	230	Target Neighborhood Hits	505	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CLIC6_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.008834 (rank : 177)
Query Neighborhood Hits	230	Target Neighborhood Hits	289	Shared Neighborhood Hits	22
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

KCNC4_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.157139 (rank : 57)
Query Neighborhood Hits	230	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG3_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.139685 (rank : 61)
Query Neighborhood Hits	230	Target Neighborhood Hits	91	Shared Neighborhood Hits	51
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KPCI_HUMAN
θ value	2.36792 (rank : 107)	NC score	-0.001783 (rank : 240)
Query Neighborhood Hits	230	Target Neighborhood Hits	885	Shared Neighborhood Hits	16
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

MCLN2_MOUSE
θ value	2.36792 (rank : 108)	NC score	0.054612 (rank : 87)
Query Neighborhood Hits	230	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MUC7_HUMAN
θ value	2.36792 (rank : 109)	NC score	0.028382 (rank : 106)
Query Neighborhood Hits	230	Target Neighborhood Hits	538	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PK2L2_HUMAN
θ value	2.36792 (rank : 110)	NC score	0.284728 (rank : 31)
Query Neighborhood Hits	230	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.251887 (rank : 37)
Query Neighborhood Hits	230	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

ADAM8_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.002978 (rank : 218)
Query Neighborhood Hits	230	Target Neighborhood Hits	326	Shared Neighborhood Hits	11
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CS007_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.019447 (rank : 133)
Query Neighborhood Hits	230	Target Neighborhood Hits	401	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CUTL2_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.004512 (rank : 208)
Query Neighborhood Hits	230	Target Neighborhood Hits	771	Shared Neighborhood Hits	20
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

GP179_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.030053 (rank : 103)
Query Neighborhood Hits	230	Target Neighborhood Hits	372	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

KCNA2_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.114944 (rank : 65)
Query Neighborhood Hits	230	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.116316 (rank : 64)
Query Neighborhood Hits	230	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCND1_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.179614 (rank : 53)
Query Neighborhood Hits	230	Target Neighborhood Hits	160	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

MAGE1_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.019313 (rank : 134)
Query Neighborhood Hits	230	Target Neighborhood Hits	1389	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NACAM_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.024131 (rank : 118)
Query Neighborhood Hits	230	Target Neighborhood Hits	1866	Shared Neighborhood Hits	98
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PAR10_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.010859 (rank : 163)
Query Neighborhood Hits	230	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

RAVR1_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.007491 (rank : 189)
Query Neighborhood Hits	230	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

SRCA_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.013105 (rank : 153)
Query Neighborhood Hits	230	Target Neighborhood Hits	380	Shared Neighborhood Hits	27
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TAB3_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.022139 (rank : 123)
Query Neighborhood Hits	230	Target Neighborhood Hits	273	Shared Neighborhood Hits	23
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TRIP6_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.003616 (rank : 212)
Query Neighborhood Hits	230	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

TRPV3_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.061326 (rank : 86)
Query Neighborhood Hits	230	Target Neighborhood Hits	198	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

ANR38_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.003799 (rank : 210)
Query Neighborhood Hits	230	Target Neighborhood Hits	512	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CEBPD_MOUSE
θ value	4.03905 (rank : 128)	NC score	0.008397 (rank : 179)
Query Neighborhood Hits	230	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

CIC_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.015645 (rank : 142)
Query Neighborhood Hits	230	Target Neighborhood Hits	742	Shared Neighborhood Hits	54
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CR1_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.003479 (rank : 213)
Query Neighborhood Hits	230	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

DEN2A_MOUSE
θ value	4.03905 (rank : 131)	NC score	0.004906 (rank : 204)
Query Neighborhood Hits	230	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

GA2L1_MOUSE
θ value	4.03905 (rank : 132)	NC score	0.026788 (rank : 110)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

HCN4_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.021713 (rank : 125)
Query Neighborhood Hits	230	Target Neighborhood Hits	303	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

IWS1_MOUSE
θ value	4.03905 (rank : 134)	NC score	0.032828 (rank : 98)
Query Neighborhood Hits	230	Target Neighborhood Hits	1258	Shared Neighborhood Hits	65
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KLF13_MOUSE
θ value	4.03905 (rank : 135)	NC score	-0.003887 (rank : 246)
Query Neighborhood Hits	230	Target Neighborhood Hits	757	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

LTK_HUMAN
θ value	4.03905 (rank : 136)	NC score	-0.001430 (rank : 238)
Query Neighborhood Hits	230	Target Neighborhood Hits	774	Shared Neighborhood Hits	16
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

MARCS_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.044398 (rank : 92)
Query Neighborhood Hits	230	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MAST1_HUMAN
θ value	4.03905 (rank : 138)	NC score	-0.000430 (rank : 231)
Query Neighborhood Hits	230	Target Neighborhood Hits	1146	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MLL2_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.021489 (rank : 128)
Query Neighborhood Hits	230	Target Neighborhood Hits	1788	Shared Neighborhood Hits	78
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OGFR_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.027700 (rank : 107)
Query Neighborhood Hits	230	Target Neighborhood Hits	1582	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PHLB1_MOUSE
θ value	4.03905 (rank : 141)	NC score	0.012770 (rank : 154)
Query Neighborhood Hits	230	Target Neighborhood Hits	678	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SHC1_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.009084 (rank : 174)
Query Neighborhood Hits	230	Target Neighborhood Hits	170	Shared Neighborhood Hits	10
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

TAF6_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.011397 (rank : 159)
Query Neighborhood Hits	230	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

UBP2L_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.014377 (rank : 148)
Query Neighborhood Hits	230	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

UBP2L_MOUSE
θ value	4.03905 (rank : 145)	NC score	0.015220 (rank : 143)
Query Neighborhood Hits	230	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

VCXC_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.015124 (rank : 144)
Query Neighborhood Hits	230	Target Neighborhood Hits	139	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

5HT6R_HUMAN
θ value	5.27518 (rank : 147)	NC score	-0.000910 (rank : 237)
Query Neighborhood Hits	230	Target Neighborhood Hits	882	Shared Neighborhood Hits	5
SwissProt Accessions	P50406, Q13640	Gene names	HTR6
Domain Architecture
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).

5HT6R_MOUSE
θ value	5.27518 (rank : 148)	NC score	-0.000847 (rank : 236)
Query Neighborhood Hits	230	Target Neighborhood Hits	881	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1C8	Gene names	Htr6
Domain Architecture
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).

ASPP1_HUMAN
θ value	5.27518 (rank : 149)	NC score	0.002749 (rank : 220)
Query Neighborhood Hits	230	Target Neighborhood Hits	956	Shared Neighborhood Hits	27
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BAT2_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.031445 (rank : 100)
Query Neighborhood Hits	230	Target Neighborhood Hits	947	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CABIN_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.022884 (rank : 121)
Query Neighborhood Hits	230	Target Neighborhood Hits	490	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

DOK1_MOUSE
θ value	5.27518 (rank : 152)	NC score	0.006445 (rank : 192)
Query Neighborhood Hits	230	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DTX2_MOUSE
θ value	5.27518 (rank : 153)	NC score	0.007717 (rank : 185)
Query Neighborhood Hits	230	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

EDN3_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.025452 (rank : 114)
Query Neighborhood Hits	230	Target Neighborhood Hits	61	Shared Neighborhood Hits	9
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

FOXM1_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.003634 (rank : 211)
Query Neighborhood Hits	230	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	O08696	Gene names	Foxm1, Fkh16
Domain Architecture
Description	Forkhead box protein M1 (Forkhead homolog 16) (Winged-helix transcription factor Trident).

GNAS1_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.008652 (rank : 178)
Query Neighborhood Hits	230	Target Neighborhood Hits	278	Shared Neighborhood Hits	25
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HCN4_MOUSE
θ value	5.27518 (rank : 157)	NC score	0.018068 (rank : 136)
Query Neighborhood Hits	230	Target Neighborhood Hits	284	Shared Neighborhood Hits	31
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

IF4G3_HUMAN
θ value	5.27518 (rank : 158)	NC score	0.005764 (rank : 195)
Query Neighborhood Hits	230	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.008245 (rank : 180)
Query Neighborhood Hits	230	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P27352	Gene names	GIF, IFMH
Domain Architecture
Description	Gastric intrinsic factor precursor (Intrinsic factor) (IF) (INF).

KCNA3_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.105799 (rank : 69)
Query Neighborhood Hits	230	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA6_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.109232 (rank : 68)
Query Neighborhood Hits	230	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

LAMP3_HUMAN
θ value	5.27518 (rank : 162)	NC score	0.008853 (rank : 176)
Query Neighborhood Hits	230	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQV4, O94781, Q8NEC8	Gene names	LAMP3, DCLAMP, TSC403
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD208 antigen).

MILK1_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.024551 (rank : 117)
Query Neighborhood Hits	230	Target Neighborhood Hits	788	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MLL4_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.022414 (rank : 122)
Query Neighborhood Hits	230	Target Neighborhood Hits	722	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PCLO_HUMAN
θ value	5.27518 (rank : 165)	NC score	0.026056 (rank : 111)
Query Neighborhood Hits	230	Target Neighborhood Hits	2046	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PGCA_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.007296 (rank : 190)
Query Neighborhood Hits	230	Target Neighborhood Hits	821	Shared Neighborhood Hits	39
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SRRM2_HUMAN
θ value	5.27518 (rank : 167)	NC score	0.032233 (rank : 99)
Query Neighborhood Hits	230	Target Neighborhood Hits	1296	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYTL1_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.005568 (rank : 196)
Query Neighborhood Hits	230	Target Neighborhood Hits	314	Shared Neighborhood Hits	15
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TITIN_HUMAN
θ value	5.27518 (rank : 169)	NC score	-0.000111 (rank : 230)
Query Neighborhood Hits	230	Target Neighborhood Hits	2923	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TMM24_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.010030 (rank : 169)
Query Neighborhood Hits	230	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

TREF1_MOUSE
θ value	5.27518 (rank : 171)	NC score	0.007685 (rank : 186)
Query Neighborhood Hits	230	Target Neighborhood Hits	682	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

TRIO_HUMAN
θ value	5.27518 (rank : 172)	NC score	-0.002270 (rank : 241)
Query Neighborhood Hits	230	Target Neighborhood Hits	1580	Shared Neighborhood Hits	32
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TTBK1_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.003304 (rank : 216)
Query Neighborhood Hits	230	Target Neighborhood Hits	1058	Shared Neighborhood Hits	43
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

WASF2_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.009640 (rank : 170)
Query Neighborhood Hits	230	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WNK1_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.000382 (rank : 229)
Query Neighborhood Hits	230	Target Neighborhood Hits	1179	Shared Neighborhood Hits	38
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ADA19_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.002909 (rank : 219)
Query Neighborhood Hits	230	Target Neighborhood Hits	381	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA1B_HUMAN
θ value	6.88961 (rank : 177)	NC score	-0.004876 (rank : 247)
Query Neighborhood Hits	230	Target Neighborhood Hits	978	Shared Neighborhood Hits	5
SwissProt Accessions	P35368	Gene names	ADRA1B
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

APTX_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.007503 (rank : 188)
Query Neighborhood Hits	230	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2E3, Q5T781, Q7Z2F3, Q7Z336, Q7Z5R5, Q7Z6V7, Q7Z6V8, Q9NXM5	Gene names	APTX
Domain Architecture
Description	Aprataxin (Forkhead-associated domain histidine triad-like protein) (FHA-HIT).

AQR_MOUSE
θ value	6.88961 (rank : 179)	NC score	0.005295 (rank : 199)
Query Neighborhood Hits	230	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

BAT3_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.027664 (rank : 108)
Query Neighborhood Hits	230	Target Neighborhood Hits	490	Shared Neighborhood Hits	46
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BSN_MOUSE
θ value	6.88961 (rank : 181)	NC score	0.036970 (rank : 96)
Query Neighborhood Hits	230	Target Neighborhood Hits	2057	Shared Neighborhood Hits	100
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CNGB1_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.004848 (rank : 206)
Query Neighborhood Hits	230	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

FA48A_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.007970 (rank : 181)
Query Neighborhood Hits	230	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TT00, Q8BG53, Q9JLS9	Gene names	Fam48a, D3Ertd300e
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

LSD1_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.004673 (rank : 207)
Query Neighborhood Hits	230	Target Neighborhood Hits	224	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MARK4_MOUSE
θ value	6.88961 (rank : 185)	NC score	-0.000765 (rank : 234)
Query Neighborhood Hits	230	Target Neighborhood Hits	898	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MEGF8_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.002585 (rank : 221)
Query Neighborhood Hits	230	Target Neighborhood Hits	520	Shared Neighborhood Hits	13
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MUC1_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.020582 (rank : 131)
Query Neighborhood Hits	230	Target Neighborhood Hits	975	Shared Neighborhood Hits	75
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NPBL_MOUSE
θ value	6.88961 (rank : 188)	NC score	0.031227 (rank : 101)
Query Neighborhood Hits	230	Target Neighborhood Hits	1041	Shared Neighborhood Hits	46
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PZRN3_MOUSE
θ value	6.88961 (rank : 189)	NC score	0.000832 (rank : 226)
Query Neighborhood Hits	230	Target Neighborhood Hits	447	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RNF39_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.002488 (rank : 222)
Query Neighborhood Hits	230	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RP3A_MOUSE
θ value	6.88961 (rank : 191)	NC score	0.009191 (rank : 172)
Query Neighborhood Hits	230	Target Neighborhood Hits	510	Shared Neighborhood Hits	42
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPGR1_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.009160 (rank : 173)
Query Neighborhood Hits	230	Target Neighborhood Hits	578	Shared Neighborhood Hits	9
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SET1A_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.012393 (rank : 155)
Query Neighborhood Hits	230	Target Neighborhood Hits	690	Shared Neighborhood Hits	38
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SIPA1_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.010965 (rank : 161)
Query Neighborhood Hits	230	Target Neighborhood Hits	250	Shared Neighborhood Hits	18
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SIPA1_MOUSE
θ value	6.88961 (rank : 195)	NC score	0.010455 (rank : 167)
Query Neighborhood Hits	230	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SOX13_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.004035 (rank : 209)
Query Neighborhood Hits	230	Target Neighborhood Hits	464	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SPEG_HUMAN
θ value	6.88961 (rank : 197)	NC score	0.005177 (rank : 201)
Query Neighborhood Hits	230	Target Neighborhood Hits	1762	Shared Neighborhood Hits	73
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYP2L_MOUSE
θ value	6.88961 (rank : 198)	NC score	0.014525 (rank : 147)
Query Neighborhood Hits	230	Target Neighborhood Hits	289	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TM108_MOUSE
θ value	6.88961 (rank : 199)	NC score	0.011477 (rank : 158)
Query Neighborhood Hits	230	Target Neighborhood Hits	336	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

UBP36_HUMAN
θ value	6.88961 (rank : 200)	NC score	0.003347 (rank : 214)
Query Neighborhood Hits	230	Target Neighborhood Hits	232	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

VCX3_HUMAN
θ value	6.88961 (rank : 201)	NC score	0.013866 (rank : 150)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

ZSWM5_HUMAN
θ value	6.88961 (rank : 202)	NC score	0.004982 (rank : 203)
Query Neighborhood Hits	230	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P217, Q5SXQ9	Gene names	ZSWIM5, KIAA1511
Domain Architecture	No domain graphic available
Description	Zinc finger SWIM domain-containing protein 5.

ABL1_HUMAN
θ value	8.99809 (rank : 203)	NC score	-0.003012 (rank : 243)
Query Neighborhood Hits	230	Target Neighborhood Hits	1220	Shared Neighborhood Hits	37
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ADA12_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.005551 (rank : 197)
Query Neighborhood Hits	230	Target Neighborhood Hits	474	Shared Neighborhood Hits	37
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BAG4_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.009006 (rank : 175)
Query Neighborhood Hits	230	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

CELR3_MOUSE
θ value	8.99809 (rank : 206)	NC score	-0.003208 (rank : 244)
Query Neighborhood Hits	230	Target Neighborhood Hits	687	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

COHA1_HUMAN
θ value	8.99809 (rank : 207)	NC score	0.010562 (rank : 165)
Query Neighborhood Hits	230	Target Neighborhood Hits	400	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CT174_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.013815 (rank : 151)
Query Neighborhood Hits	230	Target Neighborhood Hits	181	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DBP_HUMAN
θ value	8.99809 (rank : 209)	NC score	0.005851 (rank : 194)
Query Neighborhood Hits	230	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

DTX1_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.007866 (rank : 183)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

FOG1_MOUSE
θ value	8.99809 (rank : 211)	NC score	0.007873 (rank : 182)
Query Neighborhood Hits	230	Target Neighborhood Hits	1237	Shared Neighborhood Hits	62
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GGN_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.046800 (rank : 91)
Query Neighborhood Hits	230	Target Neighborhood Hits	269	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

INCE_MOUSE
θ value	8.99809 (rank : 213)	NC score	-0.002482 (rank : 242)
Query Neighborhood Hits	230	Target Neighborhood Hits	903	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

JIP1_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.010890 (rank : 162)
Query Neighborhood Hits	230	Target Neighborhood Hits	271	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

KCNA3_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.103719 (rank : 73)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA6_MOUSE
θ value	8.99809 (rank : 216)	NC score	0.111453 (rank : 66)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCND1_MOUSE
θ value	8.99809 (rank : 217)	NC score	0.179234 (rank : 54)
Query Neighborhood Hits	230	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNK4_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.010533 (rank : 166)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

LCTL_MOUSE
θ value	8.99809 (rank : 219)	NC score	0.003343 (rank : 215)
Query Neighborhood Hits	230	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1F9, Q8BPR1, Q8K2M9	Gene names	Lctl, Klph
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

PAK4_HUMAN
θ value	8.99809 (rank : 220)	NC score	-0.001536 (rank : 239)
Query Neighborhood Hits	230	Target Neighborhood Hits	924	Shared Neighborhood Hits	25
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PGCB_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.001770 (rank : 224)
Query Neighborhood Hits	230	Target Neighborhood Hits	478	Shared Neighborhood Hits	21
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PKD2_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.232147 (rank : 42)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PTPRJ_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.000665 (rank : 228)
Query Neighborhood Hits	230	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

RAGE_MOUSE
θ value	8.99809 (rank : 224)	NC score	0.005345 (rank : 198)
Query Neighborhood Hits	230	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

SLIK4_HUMAN
θ value	8.99809 (rank : 225)	NC score	-0.000641 (rank : 233)
Query Neighborhood Hits	230	Target Neighborhood Hits	287	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IW52, Q8TCM8, Q96DL3	Gene names	SLITRK4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

SLIK4_MOUSE
θ value	8.99809 (rank : 226)	NC score	-0.000636 (rank : 232)
Query Neighborhood Hits	230	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q810B8, Q8BL56, Q8BWB0, Q8BYG4, Q8C056	Gene names	Slitrk4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

TCOF_HUMAN
θ value	8.99809 (rank : 227)	NC score	0.016108 (rank : 139)
Query Neighborhood Hits	230	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

WASIP_HUMAN
θ value	8.99809 (rank : 228)	NC score	0.037647 (rank : 95)
Query Neighborhood Hits	230	Target Neighborhood Hits	458	Shared Neighborhood Hits	39
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ZFHX2_HUMAN
θ value	8.99809 (rank : 229)	NC score	0.000787 (rank : 227)
Query Neighborhood Hits	230	Target Neighborhood Hits	1178	Shared Neighborhood Hits	27
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ZIC2_MOUSE
θ value	8.99809 (rank : 230)	NC score	-0.003424 (rank : 245)
Query Neighborhood Hits	230	Target Neighborhood Hits	727	Shared Neighborhood Hits	13
SwissProt Accessions	Q62520	Gene names	Zic2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2).

KCMA1_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.051132 (rank : 90)
Query Neighborhood Hits	230	Target Neighborhood Hits	96	Shared Neighborhood Hits	38
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.051250 (rank : 89)
Query Neighborhood Hits	230	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNA4_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.092747 (rank : 79)
Query Neighborhood Hits	230	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.093010 (rank : 78)
Query Neighborhood Hits	230	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.101196 (rank : 75)
Query Neighborhood Hits	230	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.105668 (rank : 70)
Query Neighborhood Hits	230	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNG1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.109693 (rank : 67)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.105634 (rank : 71)
Query Neighborhood Hits	230	Target Neighborhood Hits	83	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.103446 (rank : 74)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.073616 (rank : 83)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.070967 (rank : 85)
Query Neighborhood Hits	230	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.074341 (rank : 82)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.073572 (rank : 84)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ4_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.098592 (rank : 76)
Query Neighborhood Hits	230	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ5_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.085844 (rank : 80)
Query Neighborhood Hits	230	Target Neighborhood Hits	163	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

PKDRE_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.083230 (rank : 81)
Query Neighborhood Hits	230	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.054337 (rank : 88)
Query Neighborhood Hits	230	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

Hits sorted by NC score

CAC1H_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	230	Target Neighborhood Hits	230	Shared Neighborhood Hits	230
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.984657 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	230	Target Neighborhood Hits	307	Shared Neighborhood Hits	105
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1I_HUMAN
NC score	0.983744 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	230	Target Neighborhood Hits	138	Shared Neighborhood Hits	76
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1G_HUMAN
NC score	0.955236 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	230	Target Neighborhood Hits	587	Shared Neighborhood Hits	105
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SC11A_HUMAN
NC score	0.892836 (rank : 5)	θ value	3.11973e-85 (rank : 5)
Query Neighborhood Hits	230	Target Neighborhood Hits	111	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
NC score	0.890917 (rank : 6)	θ value	3.82246e-75 (rank : 6)
Query Neighborhood Hits	230	Target Neighborhood Hits	116	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN4A_HUMAN
NC score	0.884121 (rank : 7)	θ value	3.82246e-75 (rank : 7)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	70
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

CAC1E_MOUSE
NC score	0.881842 (rank : 8)	θ value	2.65329e-68 (rank : 16)
Query Neighborhood Hits	230	Target Neighborhood Hits	167	Shared Neighborhood Hits	63
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.881609 (rank : 9)	θ value	1.5555e-68 (rank : 15)
Query Neighborhood Hits	230	Target Neighborhood Hits	148	Shared Neighborhood Hits	62
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN5A_HUMAN
NC score	0.880581 (rank : 10)	θ value	3.96481e-64 (rank : 23)
Query Neighborhood Hits	230	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1S_MOUSE
NC score	0.877533 (rank : 11)	θ value	8.24801e-70 (rank : 14)
Query Neighborhood Hits	230	Target Neighborhood Hits	98	Shared Neighborhood Hits	64
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN3A_HUMAN
NC score	0.877256 (rank : 12)	θ value	2.73936e-73 (rank : 10)
Query Neighborhood Hits	230	Target Neighborhood Hits	115	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CAC1D_HUMAN
NC score	0.876504 (rank : 13)	θ value	7.45998e-71 (rank : 12)
Query Neighborhood Hits	230	Target Neighborhood Hits	118	Shared Neighborhood Hits	64
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

SCN7A_HUMAN
NC score	0.876186 (rank : 14)	θ value	1.7238e-59 (rank : 29)
Query Neighborhood Hits	230	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1S_HUMAN
NC score	0.875917 (rank : 15)	θ value	2.4834e-66 (rank : 18)
Query Neighborhood Hits	230	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1A_MOUSE
NC score	0.875810 (rank : 16)	θ value	7.47731e-63 (rank : 27)
Query Neighborhood Hits	230	Target Neighborhood Hits	267	Shared Neighborhood Hits	84
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
NC score	0.873759 (rank : 17)	θ value	1.77973e-64 (rank : 21)
Query Neighborhood Hits	230	Target Neighborhood Hits	257	Shared Neighborhood Hits	77
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SCN2A_HUMAN
NC score	0.873070 (rank : 18)	θ value	2.73936e-73 (rank : 9)
Query Neighborhood Hits	230	Target Neighborhood Hits	157	Shared Neighborhood Hits	58
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN9A_HUMAN
NC score	0.872989 (rank : 19)	θ value	6.7473e-72 (rank : 11)
Query Neighborhood Hits	230	Target Neighborhood Hits	157	Shared Neighborhood Hits	63
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN1A_HUMAN
NC score	0.872736 (rank : 20)	θ value	1.66191e-70 (rank : 13)
Query Neighborhood Hits	230	Target Neighborhood Hits	148	Shared Neighborhood Hits	61
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SC10A_MOUSE
NC score	0.872261 (rank : 21)	θ value	3.71096e-62 (rank : 28)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	64
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

CAC1B_MOUSE
NC score	0.871780 (rank : 22)	θ value	1.31681e-67 (rank : 17)
Query Neighborhood Hits	230	Target Neighborhood Hits	351	Shared Neighborhood Hits	93
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SCN8A_HUMAN
NC score	0.871373 (rank : 23)	θ value	7.98882e-65 (rank : 20)
Query Neighborhood Hits	230	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC10A_HUMAN
NC score	0.870888 (rank : 24)	θ value	2.47765e-74 (rank : 8)
Query Neighborhood Hits	230	Target Neighborhood Hits	116	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

CAC1F_HUMAN
NC score	0.870875 (rank : 25)	θ value	3.58603e-65 (rank : 19)
Query Neighborhood Hits	230	Target Neighborhood Hits	141	Shared Neighborhood Hits	65
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
NC score	0.870556 (rank : 26)	θ value	8.83269e-64 (rank : 26)
Query Neighborhood Hits	230	Target Neighborhood Hits	142	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1A_HUMAN
NC score	0.869745 (rank : 27)	θ value	3.96481e-64 (rank : 22)
Query Neighborhood Hits	230	Target Neighborhood Hits	387	Shared Neighborhood Hits	92
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SCN8A_MOUSE
NC score	0.869092 (rank : 28)	θ value	3.96481e-64 (rank : 24)
Query Neighborhood Hits	230	Target Neighborhood Hits	136	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1C_MOUSE
NC score	0.868803 (rank : 29)	θ value	6.76295e-64 (rank : 25)
Query Neighborhood Hits	230	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.862526 (rank : 30)	θ value	7.24236e-58 (rank : 30)
Query Neighborhood Hits	230	Target Neighborhood Hits	158	Shared Neighborhood Hits	60
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

PK2L2_HUMAN
NC score	0.284728 (rank : 31)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	230	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCNV2_HUMAN
NC score	0.271886 (rank : 32)	θ value	1.09739e-05 (rank : 35)
Query Neighborhood Hits	230	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

PK2L1_HUMAN
NC score	0.269835 (rank : 33)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	230	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

KCNF1_HUMAN
NC score	0.266847 (rank : 34)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNB2_HUMAN
NC score	0.256258 (rank : 35)	θ value	1.43324e-05 (rank : 36)
Query Neighborhood Hits	230	Target Neighborhood Hits	212	Shared Neighborhood Hits	69
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.254430 (rank : 36)	θ value	4.92598e-06 (rank : 33)
Query Neighborhood Hits	230	Target Neighborhood Hits	130	Shared Neighborhood Hits	66
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

PK2L2_MOUSE
NC score	0.251887 (rank : 37)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	230	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCNS2_HUMAN
NC score	0.249963 (rank : 38)	θ value	6.43352e-06 (rank : 34)
Query Neighborhood Hits	230	Target Neighborhood Hits	129	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

PKD2_MOUSE
NC score	0.248246 (rank : 39)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

KCNB1_HUMAN
NC score	0.246281 (rank : 40)	θ value	7.59969e-07 (rank : 31)
Query Neighborhood Hits	230	Target Neighborhood Hits	169	Shared Neighborhood Hits	66
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
NC score	0.246265 (rank : 41)	θ value	7.59969e-07 (rank : 32)
Query Neighborhood Hits	230	Target Neighborhood Hits	154	Shared Neighborhood Hits	65
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

PKD2_HUMAN
NC score	0.232147 (rank : 42)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNS3_HUMAN
NC score	0.218959 (rank : 43)	θ value	0.00390308 (rank : 42)
Query Neighborhood Hits	230	Target Neighborhood Hits	125	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND3_MOUSE
NC score	0.202974 (rank : 44)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	230	Target Neighborhood Hits	162	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.202791 (rank : 45)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	230	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND2_MOUSE
NC score	0.201674 (rank : 46)	θ value	0.0113563 (rank : 44)
Query Neighborhood Hits	230	Target Neighborhood Hits	156	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.201228 (rank : 47)	θ value	0.0148317 (rank : 45)
Query Neighborhood Hits	230	Target Neighborhood Hits	154	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNS1_HUMAN
NC score	0.197969 (rank : 48)	θ value	9.29e-05 (rank : 38)
Query Neighborhood Hits	230	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

TPTE2_HUMAN
NC score	0.192249 (rank : 49)	θ value	9.29e-05 (rank : 39)
Query Neighborhood Hits	230	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNS1_MOUSE
NC score	0.187031 (rank : 50)	θ value	4.1701e-05 (rank : 37)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.185490 (rank : 51)	θ value	0.00175202 (rank : 41)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.184157 (rank : 52)	θ value	0.00134147 (rank : 40)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCND1_HUMAN
NC score	0.179614 (rank : 53)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	230	Target Neighborhood Hits	160	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND1_MOUSE
NC score	0.179234 (rank : 54)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	230	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNC4_HUMAN
NC score	0.168930 (rank : 55)	θ value	0.0961366 (rank : 50)
Query Neighborhood Hits	230	Target Neighborhood Hits	141	Shared Neighborhood Hits	60
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC3_HUMAN
NC score	0.158095 (rank : 56)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	230	Target Neighborhood Hits	256	Shared Neighborhood Hits	72
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC4_MOUSE
NC score	0.157139 (rank : 57)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	230	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_MOUSE
NC score	0.155417 (rank : 58)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	230	Target Neighborhood Hits	173	Shared Neighborhood Hits	63
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

TPTE_HUMAN
NC score	0.141722 (rank : 59)	θ value	0.00390308 (rank : 43)
Query Neighborhood Hits	230	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNG3_HUMAN
NC score	0.140577 (rank : 60)	θ value	1.06291 (rank : 86)
Query Neighborhood Hits	230	Target Neighborhood Hits	91	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.139685 (rank : 61)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	230	Target Neighborhood Hits	91	Shared Neighborhood Hits	51
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNA1_MOUSE
NC score	0.120904 (rank : 62)	θ value	1.06291 (rank : 85)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.118532 (rank : 63)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	47
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA2_MOUSE
NC score	0.116316 (rank : 64)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	230	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.114944 (rank : 65)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	230	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA6_MOUSE
NC score	0.111453 (rank : 66)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG1_HUMAN
NC score	0.109693 (rank : 67)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNA6_HUMAN
NC score	0.109232 (rank : 68)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	230	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA3_HUMAN
NC score	0.105799 (rank : 69)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	230	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA5_MOUSE
NC score	0.105668 (rank : 70)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	230	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNG2_HUMAN
NC score	0.105634 (rank : 71)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	230	Target Neighborhood Hits	83	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNQ1_MOUSE
NC score	0.104275 (rank : 72)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	230	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA3_MOUSE
NC score	0.103719 (rank : 73)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNG4_HUMAN
NC score	0.103446 (rank : 74)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNA5_HUMAN
NC score	0.101196 (rank : 75)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	230	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNQ4_HUMAN
NC score	0.098592 (rank : 76)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	230	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ1_HUMAN
NC score	0.093499 (rank : 77)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA4_MOUSE
NC score	0.093010 (rank : 78)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	230	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.092747 (rank : 79)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	230	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ5_HUMAN
NC score	0.085844 (rank : 80)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	230	Target Neighborhood Hits	163	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

PKDRE_HUMAN
NC score	0.083230 (rank : 81)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	230	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNQ3_HUMAN
NC score	0.074341 (rank : 82)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_HUMAN
NC score	0.073616 (rank : 83)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_MOUSE
NC score	0.073572 (rank : 84)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_MOUSE
NC score	0.070967 (rank : 85)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	230	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

TRPV3_HUMAN
NC score	0.061326 (rank : 86)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	230	Target Neighborhood Hits	198	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

MCLN2_MOUSE
NC score	0.054612 (rank : 87)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	230	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

PKDRE_MOUSE
NC score	0.054337 (rank : 88)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	230	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCMA1_MOUSE
NC score	0.051250 (rank : 89)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	230	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.051132 (rank : 90)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	230	Target Neighborhood Hits	96	Shared Neighborhood Hits	38
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

GGN_HUMAN
NC score	0.046800 (rank : 91)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	230	Target Neighborhood Hits	269	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MARCS_HUMAN
NC score	0.044398 (rank : 92)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	230	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

GGN_MOUSE
NC score	0.041568 (rank : 93)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	230	Target Neighborhood Hits	311	Shared Neighborhood Hits	31
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

S36A1_MOUSE
NC score	0.039380 (rank : 94)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	230	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4D3, Q811N9	Gene names	Slc36a1, Pat1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

WASIP_HUMAN
NC score	0.037647 (rank : 95)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	230	Target Neighborhood Hits	458	Shared Neighborhood Hits	39
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BSN_MOUSE
NC score	0.036970 (rank : 96)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	230	Target Neighborhood Hits	2057	Shared Neighborhood Hits	100
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

YLPM1_MOUSE
NC score	0.034312 (rank : 97)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	230	Target Neighborhood Hits	505	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

IWS1_MOUSE
NC score	0.032828 (rank : 98)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	230	Target Neighborhood Hits	1258	Shared Neighborhood Hits	65
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SRRM2_HUMAN
NC score	0.032233 (rank : 99)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	230	Target Neighborhood Hits	1296	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BAT2_MOUSE
NC score	0.031445 (rank : 100)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	230	Target Neighborhood Hits	947	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NPBL_MOUSE
NC score	0.031227 (rank : 101)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	230	Target Neighborhood Hits	1041	Shared Neighborhood Hits	46
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PRRT3_HUMAN
NC score	0.030871 (rank : 102)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	230	Target Neighborhood Hits	998	Shared Neighborhood Hits	84
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

GP179_HUMAN
NC score	0.030053 (rank : 103)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	230	Target Neighborhood Hits	372	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

NCOR2_HUMAN
NC score	0.029069 (rank : 104)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	230	Target Neighborhood Hits	870	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TOIP2_MOUSE
NC score	0.028880 (rank : 105)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	230	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

MUC7_HUMAN
NC score	0.028382 (rank : 106)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	230	Target Neighborhood Hits	538	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

OGFR_HUMAN
NC score	0.027700 (rank : 107)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	230	Target Neighborhood Hits	1582	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BAT3_HUMAN
NC score	0.027664 (rank : 108)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	230	Target Neighborhood Hits	490	Shared Neighborhood Hits	46
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CJ078_MOUSE
NC score	0.027177 (rank : 109)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	230	Target Neighborhood Hits	559	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

GA2L1_MOUSE
NC score	0.026788 (rank : 110)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

PCLO_HUMAN
NC score	0.026056 (rank : 111)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	230	Target Neighborhood Hits	2046	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

BRCA1_MOUSE
NC score	0.025743 (rank : 112)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	230	Target Neighborhood Hits	436	Shared Neighborhood Hits	16
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

IRS2_HUMAN
NC score	0.025546 (rank : 113)	θ value	1.06291 (rank : 84)
Query Neighborhood Hits	230	Target Neighborhood Hits	262	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

EDN3_HUMAN
NC score	0.025452 (rank : 114)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	230	Target Neighborhood Hits	61	Shared Neighborhood Hits	9
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

TCOF_MOUSE
NC score	0.025249 (rank : 115)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	230	Target Neighborhood Hits	471	Shared Neighborhood Hits	37
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

REXO1_HUMAN
NC score	0.024839 (rank : 116)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	230	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

MILK1_MOUSE
NC score	0.024551 (rank : 117)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	230	Target Neighborhood Hits	788	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NACAM_MOUSE
NC score	0.024131 (rank : 118)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	230	Target Neighborhood Hits	1866	Shared Neighborhood Hits	98
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CQ050_HUMAN
NC score	0.023381 (rank : 119)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	230	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WW18, Q6Q621	Gene names	C17orf50
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf50.

TARA_MOUSE
NC score	0.023027 (rank : 120)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	230	Target Neighborhood Hits	1133	Shared Neighborhood Hits	58
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CABIN_HUMAN
NC score	0.022884 (rank : 121)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	230	Target Neighborhood Hits	490	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

MLL4_HUMAN
NC score	0.022414 (rank : 122)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	230	Target Neighborhood Hits	722	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TAB3_MOUSE
NC score	0.022139 (rank : 123)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	230	Target Neighborhood Hits	273	Shared Neighborhood Hits	23
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TMED8_HUMAN
NC score	0.021901 (rank : 124)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	230	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PL24, Q9P1V9	Gene names	TMED8
Domain Architecture	No domain graphic available
Description	Protein TMED8.

HCN4_HUMAN
NC score	0.021713 (rank : 125)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	230	Target Neighborhood Hits	303	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

SF3B4_HUMAN
NC score	0.021653 (rank : 126)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	230	Target Neighborhood Hits	445	Shared Neighborhood Hits	29
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

ASTL_HUMAN
NC score	0.021563 (rank : 127)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	230	Target Neighborhood Hits	252	Shared Neighborhood Hits	29
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

MLL2_HUMAN
NC score	0.021489 (rank : 128)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	230	Target Neighborhood Hits	1788	Shared Neighborhood Hits	78
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MKL1_HUMAN
NC score	0.021473 (rank : 129)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	230	Target Neighborhood Hits	232	Shared Neighborhood Hits	17
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

PP4R1_HUMAN
NC score	0.020760 (rank : 130)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	230	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

MUC1_HUMAN
NC score	0.020582 (rank : 131)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	230	Target Neighborhood Hits	975	Shared Neighborhood Hits	75
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

K0586_HUMAN
NC score	0.019841 (rank : 132)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	230	Target Neighborhood Hits	311	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

CS007_HUMAN
NC score	0.019447 (rank : 133)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	230	Target Neighborhood Hits	401	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

MAGE1_HUMAN
NC score	0.019313 (rank : 134)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	230	Target Neighborhood Hits	1389	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

UN119_HUMAN
NC score	0.018944 (rank : 135)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	230	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q13432, O95126	Gene names	UNC119, RG4
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (HRG4).

HCN4_MOUSE
NC score	0.018068 (rank : 136)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	230	Target Neighborhood Hits	284	Shared Neighborhood Hits	31
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

KCNK4_MOUSE
NC score	0.017882 (rank : 137)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	230	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

COHA1_MOUSE
NC score	0.017662 (rank : 138)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	230	Target Neighborhood Hits	414	Shared Neighborhood Hits	25
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

TCOF_HUMAN
NC score	0.016108 (rank : 139)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	230	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TERF2_MOUSE
NC score	0.016040 (rank : 140)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	230	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

NCOR2_MOUSE
NC score	0.015884 (rank : 141)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	230	Target Neighborhood Hits	790	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

CIC_MOUSE
NC score	0.015645 (rank : 142)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	230	Target Neighborhood Hits	742	Shared Neighborhood Hits	54
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

UBP2L_MOUSE
NC score	0.015220 (rank : 143)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	230	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

VCXC_HUMAN
NC score	0.015124 (rank : 144)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	230	Target Neighborhood Hits	139	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

BCAS1_HUMAN
NC score	0.015120 (rank : 145)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

SON_HUMAN
NC score	0.014758 (rank : 146)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	230	Target Neighborhood Hits	1568	Shared Neighborhood Hits	83
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SYP2L_MOUSE
NC score	0.014525 (rank : 147)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	230	Target Neighborhood Hits	289	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

UBP2L_HUMAN
NC score	0.014377 (rank : 148)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	230	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

MUCDL_HUMAN
NC score	0.014246 (rank : 149)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	230	Target Neighborhood Hits	777	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

VCX3_HUMAN
NC score	0.013866 (rank : 150)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

CT174_HUMAN
NC score	0.013815 (rank : 151)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	230	Target Neighborhood Hits	181	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

SOS1_MOUSE
NC score	0.013806 (rank : 152)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	230	Target Neighborhood Hits	281	Shared Neighborhood Hits	14
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SRCA_HUMAN
NC score	0.013105 (rank : 153)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	230	Target Neighborhood Hits	380	Shared Neighborhood Hits	27
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

PHLB1_MOUSE
NC score	0.012770 (rank : 154)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	230	Target Neighborhood Hits	678	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SET1A_HUMAN
NC score	0.012393 (rank : 155)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	230	Target Neighborhood Hits	690	Shared Neighborhood Hits	38
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

RGS6_HUMAN
NC score	0.012289 (rank : 156)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	230	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

SSH2_MOUSE
NC score	0.011899 (rank : 157)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	230	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

TM108_MOUSE
NC score	0.011477 (rank : 158)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	230	Target Neighborhood Hits	336	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TAF6_HUMAN
NC score	0.011397 (rank : 159)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	230	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

CSKI2_HUMAN
NC score	0.011075 (rank : 160)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	230	Target Neighborhood Hits	747	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

SIPA1_HUMAN
NC score	0.010965 (rank : 161)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	230	Target Neighborhood Hits	250	Shared Neighborhood Hits	18
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

JIP1_HUMAN
NC score	0.010890 (rank : 162)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	230	Target Neighborhood Hits	271	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

PAR10_HUMAN
NC score	0.010859 (rank : 163)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	230	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

SAFB2_MOUSE
NC score	0.010650 (rank : 164)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	230	Target Neighborhood Hits	581	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

COHA1_HUMAN
NC score	0.010562 (rank : 165)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	230	Target Neighborhood Hits	400	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

KCNK4_HUMAN
NC score	0.010533 (rank : 166)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

SIPA1_MOUSE
NC score	0.010455 (rank : 167)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	230	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

DPOLZ_MOUSE
NC score	0.010195 (rank : 168)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	230	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

TMM24_HUMAN
NC score	0.010030 (rank : 169)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	230	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

WASF2_HUMAN
NC score	0.009640 (rank : 170)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	230	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

PLXB1_HUMAN
NC score	0.009626 (rank : 171)	θ value	0.813845 (rank : 77)
Query Neighborhood Hits	230	Target Neighborhood Hits	360	Shared Neighborhood Hits	29
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

RP3A_MOUSE
NC score	0.009191 (rank : 172)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	230	Target Neighborhood Hits	510	Shared Neighborhood Hits	42
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPGR1_HUMAN
NC score	0.009160 (rank : 173)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	230	Target Neighborhood Hits	578	Shared Neighborhood Hits	9
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SHC1_HUMAN
NC score	0.009084 (rank : 174)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	230	Target Neighborhood Hits	170	Shared Neighborhood Hits	10
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

BAG4_HUMAN
NC score	0.009006 (rank : 175)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	230	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

LAMP3_HUMAN
NC score	0.008853 (rank : 176)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	230	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQV4, O94781, Q8NEC8	Gene names	LAMP3, DCLAMP, TSC403
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD208 antigen).

CLIC6_HUMAN
NC score	0.008834 (rank : 177)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	230	Target Neighborhood Hits	289	Shared Neighborhood Hits	22
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

GNAS1_HUMAN
NC score	0.008652 (rank : 178)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	230	Target Neighborhood Hits	278	Shared Neighborhood Hits	25
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CEBPD_MOUSE
NC score	0.008397 (rank : 179)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	230	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

IF_HUMAN
NC score	0.008245 (rank : 180)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	230	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P27352	Gene names	GIF, IFMH
Domain Architecture
Description	Gastric intrinsic factor precursor (Intrinsic factor) (IF) (INF).

FA48A_MOUSE
NC score	0.007970 (rank : 181)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	230	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TT00, Q8BG53, Q9JLS9	Gene names	Fam48a, D3Ertd300e
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

FOG1_MOUSE
NC score	0.007873 (rank : 182)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	230	Target Neighborhood Hits	1237	Shared Neighborhood Hits	62
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

DTX1_MOUSE
NC score	0.007866 (rank : 183)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

FOG1_HUMAN
NC score	0.007741 (rank : 184)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	230	Target Neighborhood Hits	981	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

DTX2_MOUSE
NC score	0.007717 (rank : 185)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	230	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

TREF1_MOUSE
NC score	0.007685 (rank : 186)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	230	Target Neighborhood Hits	682	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

FOXGA_HUMAN
NC score	0.007676 (rank : 187)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	230	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

APTX_HUMAN
NC score	0.007503 (rank : 188)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	230	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2E3, Q5T781, Q7Z2F3, Q7Z336, Q7Z5R5, Q7Z6V7, Q7Z6V8, Q9NXM5	Gene names	APTX
Domain Architecture
Description	Aprataxin (Forkhead-associated domain histidine triad-like protein) (FHA-HIT).

RAVR1_MOUSE
NC score	0.007491 (rank : 189)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	230	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

PGCA_HUMAN
NC score	0.007296 (rank : 190)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	230	Target Neighborhood Hits	821	Shared Neighborhood Hits	39
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CAF1A_MOUSE
NC score	0.006778 (rank : 191)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	230	Target Neighborhood Hits	736	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DOK1_MOUSE
NC score	0.006445 (rank : 192)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	230	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

TLE1_MOUSE
NC score	0.005975 (rank : 193)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	230	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

DBP_HUMAN
NC score	0.005851 (rank : 194)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	230	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

IF4G3_HUMAN
NC score	0.005764 (rank : 195)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	230	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

SYTL1_MOUSE
NC score	0.005568 (rank : 196)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	230	Target Neighborhood Hits	314	Shared Neighborhood Hits	15
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

ADA12_MOUSE
NC score	0.005551 (rank : 197)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	230	Target Neighborhood Hits	474	Shared Neighborhood Hits	37
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

RAGE_MOUSE
NC score	0.005345 (rank : 198)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	230	Target Neighborhood Hits	295	Shared Neighborhood Hits	8
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

AQR_MOUSE
NC score	0.005295 (rank : 199)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	230	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

SPEG_MOUSE
NC score	0.005199 (rank : 200)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	230	Target Neighborhood Hits	1959	Shared Neighborhood Hits	83
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_HUMAN
NC score	0.005177 (rank : 201)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	230	Target Neighborhood Hits	1762	Shared Neighborhood Hits	73
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ATS4_MOUSE
NC score	0.005077 (rank : 202)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	230	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ZSWM5_HUMAN
NC score	0.004982 (rank : 203)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	230	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P217, Q5SXQ9	Gene names	ZSWIM5, KIAA1511
Domain Architecture	No domain graphic available
Description	Zinc finger SWIM domain-containing protein 5.

DEN2A_MOUSE
NC score	0.004906 (rank : 204)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	230	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

TNKS1_HUMAN
NC score	0.004877 (rank : 205)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	230	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

CNGB1_HUMAN
NC score	0.004848 (rank : 206)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	230	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

LSD1_MOUSE
NC score	0.004673 (rank : 207)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	230	Target Neighborhood Hits	224	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

CUTL2_MOUSE
NC score	0.004512 (rank : 208)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	230	Target Neighborhood Hits	771	Shared Neighborhood Hits	20
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

SOX13_HUMAN
NC score	0.004035 (rank : 209)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	230	Target Neighborhood Hits	464	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ANR38_MOUSE
NC score	0.003799 (rank : 210)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	230	Target Neighborhood Hits	512	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

FOXM1_MOUSE
NC score	0.003634 (rank : 211)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	230	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	O08696	Gene names	Foxm1, Fkh16
Domain Architecture
Description	Forkhead box protein M1 (Forkhead homolog 16) (Winged-helix transcription factor Trident).

TRIP6_HUMAN
NC score	0.003616 (rank : 212)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	230	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

CR1_HUMAN
NC score	0.003479 (rank : 213)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	230	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

UBP36_HUMAN
NC score	0.003347 (rank : 214)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	230	Target Neighborhood Hits	232	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

LCTL_MOUSE
NC score	0.003343 (rank : 215)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	230	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1F9, Q8BPR1, Q8K2M9	Gene names	Lctl, Klph
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

TTBK1_HUMAN
NC score	0.003304 (rank : 216)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	230	Target Neighborhood Hits	1058	Shared Neighborhood Hits	43
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

M3K11_HUMAN
NC score	0.003264 (rank : 217)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	230	Target Neighborhood Hits	1136	Shared Neighborhood Hits	32
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

ADAM8_MOUSE
NC score	0.002978 (rank : 218)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	230	Target Neighborhood Hits	326	Shared Neighborhood Hits	11
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA19_HUMAN
NC score	0.002909 (rank : 219)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	230	Target Neighborhood Hits	381	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ASPP1_HUMAN
NC score	0.002749 (rank : 220)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	230	Target Neighborhood Hits	956	Shared Neighborhood Hits	27
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MEGF8_MOUSE
NC score	0.002585 (rank : 221)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	230	Target Neighborhood Hits	520	Shared Neighborhood Hits	13
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

RNF39_HUMAN
NC score	0.002488 (rank : 222)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	230	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

PAK4_MOUSE
NC score	0.002269 (rank : 223)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	230	Target Neighborhood Hits	1098	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PGCB_HUMAN
NC score	0.001770 (rank : 224)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	230	Target Neighborhood Hits	478	Shared Neighborhood Hits	21
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

M3K15_HUMAN
NC score	0.001170 (rank : 225)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	230	Target Neighborhood Hits	914	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

PZRN3_MOUSE
NC score	0.000832 (rank : 226)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	230	Target Neighborhood Hits	447	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ZFHX2_HUMAN
NC score	0.000787 (rank : 227)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	230	Target Neighborhood Hits	1178	Shared Neighborhood Hits	27
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

PTPRJ_HUMAN
NC score	0.000665 (rank : 228)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	230	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

WNK1_MOUSE
NC score	0.000382 (rank : 229)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	230	Target Neighborhood Hits	1179	Shared Neighborhood Hits	38
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

TITIN_HUMAN
NC score	-0.000111 (rank : 230)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	230	Target Neighborhood Hits	2923	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MAST1_HUMAN
NC score	-0.000430 (rank : 231)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	230	Target Neighborhood Hits	1146	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SLIK4_MOUSE
NC score	-0.000636 (rank : 232)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	230	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q810B8, Q8BL56, Q8BWB0, Q8BYG4, Q8C056	Gene names	Slitrk4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

SLIK4_HUMAN
NC score	-0.000641 (rank : 233)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	230	Target Neighborhood Hits	287	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IW52, Q8TCM8, Q96DL3	Gene names	SLITRK4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

MARK4_MOUSE
NC score	-0.000765 (rank : 234)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	230	Target Neighborhood Hits	898	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

HIC1_HUMAN
NC score	-0.000786 (rank : 235)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	230	Target Neighborhood Hits	838	Shared Neighborhood Hits	15
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

5HT6R_MOUSE
NC score	-0.000847 (rank : 236)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	230	Target Neighborhood Hits	881	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1C8	Gene names	Htr6
Domain Architecture
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).

5HT6R_HUMAN
NC score	-0.000910 (rank : 237)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	230	Target Neighborhood Hits	882	Shared Neighborhood Hits	5
SwissProt Accessions	P50406, Q13640	Gene names	HTR6
Domain Architecture
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).

LTK_HUMAN
NC score	-0.001430 (rank : 238)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	230	Target Neighborhood Hits	774	Shared Neighborhood Hits	16
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

PAK4_HUMAN
NC score	-0.001536 (rank : 239)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	230	Target Neighborhood Hits	924	Shared Neighborhood Hits	25
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

KPCI_HUMAN
NC score	-0.001783 (rank : 240)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	230	Target Neighborhood Hits	885	Shared Neighborhood Hits	16
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

TRIO_HUMAN
NC score	-0.002270 (rank : 241)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	230	Target Neighborhood Hits	1580	Shared Neighborhood Hits	32
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

INCE_MOUSE
NC score	-0.002482 (rank : 242)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	230	Target Neighborhood Hits	903	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

ABL1_HUMAN
NC score	-0.003012 (rank : 243)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	230	Target Neighborhood Hits	1220	Shared Neighborhood Hits	37
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CELR3_MOUSE
NC score	-0.003208 (rank : 244)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	230	Target Neighborhood Hits	687	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

ZIC2_MOUSE
NC score	-0.003424 (rank : 245)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	230	Target Neighborhood Hits	727	Shared Neighborhood Hits	13
SwissProt Accessions	Q62520	Gene names	Zic2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2).

KLF13_MOUSE
NC score	-0.003887 (rank : 246)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	230	Target Neighborhood Hits	757	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

ADA1B_HUMAN
NC score	-0.004876 (rank : 247)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	230	Target Neighborhood Hits	978	Shared Neighborhood Hits	5
SwissProt Accessions	P35368	Gene names	ADRA1B
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).