Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : HCN4_MOUSE

For an explanation of this page, click here

HCN4_MOUSE
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.970029 (rank : 5)
Query Neighborhood Hits	284	Target Neighborhood Hits	120	Shared Neighborhood Hits	66
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	0 (rank : 2)	NC score	0.967669 (rank : 7)
Query Neighborhood Hits	284	Target Neighborhood Hits	172	Shared Neighborhood Hits	64
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_HUMAN
θ value	0 (rank : 3)	NC score	0.964523 (rank : 8)
Query Neighborhood Hits	284	Target Neighborhood Hits	369	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	0 (rank : 4)	NC score	0.969965 (rank : 6)
Query Neighborhood Hits	284	Target Neighborhood Hits	278	Shared Neighborhood Hits	122
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN3_HUMAN
θ value	0 (rank : 5)	NC score	0.970621 (rank : 4)
Query Neighborhood Hits	284	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	0 (rank : 6)	NC score	0.970977 (rank : 3)
Query Neighborhood Hits	284	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN4_HUMAN
θ value	0 (rank : 7)	NC score	0.983167 (rank : 2)
Query Neighborhood Hits	284	Target Neighborhood Hits	303	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	0 (rank : 8)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	284	Target Neighborhood Hits	284	Shared Neighborhood Hits	284
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CNGA1_MOUSE
θ value	1.01529e-43 (rank : 9)	NC score	0.834307 (rank : 12)
Query Neighborhood Hits	284	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
θ value	8.59492e-43 (rank : 10)	NC score	0.845351 (rank : 9)
Query Neighborhood Hits	284	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
θ value	1.46607e-42 (rank : 11)	NC score	0.835294 (rank : 11)
Query Neighborhood Hits	284	Target Neighborhood Hits	149	Shared Neighborhood Hits	44
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	6.15952e-41 (rank : 12)	NC score	0.839393 (rank : 10)
Query Neighborhood Hits	284	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
θ value	3.99248e-40 (rank : 13)	NC score	0.833124 (rank : 13)
Query Neighborhood Hits	284	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

KCNH6_HUMAN
θ value	1.98146e-39 (rank : 14)	NC score	0.793216 (rank : 17)
Query Neighborhood Hits	284	Target Neighborhood Hits	222	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_MOUSE
θ value	1.6774e-38 (rank : 15)	NC score	0.790278 (rank : 19)
Query Neighborhood Hits	284	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
θ value	1.6774e-38 (rank : 16)	NC score	0.785793 (rank : 20)
Query Neighborhood Hits	284	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH2_HUMAN
θ value	2.19075e-38 (rank : 17)	NC score	0.790299 (rank : 18)
Query Neighborhood Hits	284	Target Neighborhood Hits	158	Shared Neighborhood Hits	56
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH7_HUMAN
θ value	4.568e-36 (rank : 18)	NC score	0.781018 (rank : 21)
Query Neighborhood Hits	284	Target Neighborhood Hits	107	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH5_HUMAN
θ value	1.01765e-35 (rank : 19)	NC score	0.775728 (rank : 24)
Query Neighborhood Hits	284	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	1.32909e-35 (rank : 20)	NC score	0.775823 (rank : 23)
Query Neighborhood Hits	284	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH8_HUMAN
θ value	1.9192e-34 (rank : 21)	NC score	0.772171 (rank : 25)
Query Neighborhood Hits	284	Target Neighborhood Hits	104	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

CNGB1_HUMAN
θ value	7.29293e-34 (rank : 22)	NC score	0.815344 (rank : 15)
Query Neighborhood Hits	284	Target Neighborhood Hits	222	Shared Neighborhood Hits	65
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH1_HUMAN
θ value	9.52487e-34 (rank : 23)	NC score	0.770212 (rank : 27)
Query Neighborhood Hits	284	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	9.52487e-34 (rank : 24)	NC score	0.770573 (rank : 26)
Query Neighborhood Hits	284	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

CNGB3_MOUSE
θ value	1.79631e-32 (rank : 25)	NC score	0.818549 (rank : 14)
Query Neighborhood Hits	284	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

KCNH4_HUMAN
θ value	5.22648e-32 (rank : 26)	NC score	0.777796 (rank : 22)
Query Neighborhood Hits	284	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

CNGB3_HUMAN
θ value	3.3877e-31 (rank : 27)	NC score	0.804624 (rank : 16)
Query Neighborhood Hits	284	Target Neighborhood Hits	206	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH3_HUMAN
θ value	5.40856e-29 (rank : 28)	NC score	0.764949 (rank : 28)
Query Neighborhood Hits	284	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	5.40856e-29 (rank : 29)	NC score	0.762826 (rank : 29)
Query Neighborhood Hits	284	Target Neighborhood Hits	133	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_HUMAN
θ value	9.92553e-07 (rank : 30)	NC score	0.324588 (rank : 30)
Query Neighborhood Hits	284	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
θ value	1.29631e-06 (rank : 31)	NC score	0.296572 (rank : 31)
Query Neighborhood Hits	284	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KGP2_MOUSE
θ value	1.69304e-06 (rank : 32)	NC score	0.083956 (rank : 60)
Query Neighborhood Hits	284	Target Neighborhood Hits	1029	Shared Neighborhood Hits	58
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
θ value	2.21117e-06 (rank : 33)	NC score	0.083803 (rank : 61)
Query Neighborhood Hits	284	Target Neighborhood Hits	1023	Shared Neighborhood Hits	59
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

MUC1_HUMAN
θ value	2.88788e-06 (rank : 34)	NC score	0.074640 (rank : 73)
Query Neighborhood Hits	284	Target Neighborhood Hits	975	Shared Neighborhood Hits	96
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

KAP2_MOUSE
θ value	8.40245e-06 (rank : 35)	NC score	0.272003 (rank : 34)
Query Neighborhood Hits	284	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
θ value	1.43324e-05 (rank : 36)	NC score	0.267930 (rank : 35)
Query Neighborhood Hits	284	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

RGS3_MOUSE
θ value	5.44631e-05 (rank : 37)	NC score	0.086040 (rank : 54)
Query Neighborhood Hits	284	Target Neighborhood Hits	1621	Shared Neighborhood Hits	136
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

KGP1B_MOUSE
θ value	0.000121331 (rank : 38)	NC score	0.084626 (rank : 57)
Query Neighborhood Hits	284	Target Neighborhood Hits	922	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

SRRM2_MOUSE
θ value	0.000121331 (rank : 39)	NC score	0.108484 (rank : 41)
Query Neighborhood Hits	284	Target Neighborhood Hits	1470	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

KGP1A_HUMAN
θ value	0.00020696 (rank : 40)	NC score	0.084291 (rank : 59)
Query Neighborhood Hits	284	Target Neighborhood Hits	901	Shared Neighborhood Hits	62
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.00020696 (rank : 41)	NC score	0.084597 (rank : 58)
Query Neighborhood Hits	284	Target Neighborhood Hits	921	Shared Neighborhood Hits	62
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

TCGAP_HUMAN
θ value	0.00020696 (rank : 42)	NC score	0.056776 (rank : 137)
Query Neighborhood Hits	284	Target Neighborhood Hits	872	Shared Neighborhood Hits	87
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MAGE1_HUMAN
θ value	0.000270298 (rank : 43)	NC score	0.077492 (rank : 67)
Query Neighborhood Hits	284	Target Neighborhood Hits	1389	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NACAM_MOUSE
θ value	0.00035302 (rank : 44)	NC score	0.108550 (rank : 40)
Query Neighborhood Hits	284	Target Neighborhood Hits	1866	Shared Neighborhood Hits	160
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

KAP3_MOUSE
θ value	0.000461057 (rank : 45)	NC score	0.261111 (rank : 36)
Query Neighborhood Hits	284	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
θ value	0.00102713 (rank : 46)	NC score	0.255653 (rank : 37)
Query Neighborhood Hits	284	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP1_HUMAN
θ value	0.00134147 (rank : 47)	NC score	0.287167 (rank : 32)
Query Neighborhood Hits	284	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	0.00134147 (rank : 48)	NC score	0.284271 (rank : 33)
Query Neighborhood Hits	284	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

CBL_MOUSE
θ value	0.00228821 (rank : 49)	NC score	0.049258 (rank : 185)
Query Neighborhood Hits	284	Target Neighborhood Hits	426	Shared Neighborhood Hits	37
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

MAST4_HUMAN
θ value	0.00228821 (rank : 50)	NC score	0.029246 (rank : 228)
Query Neighborhood Hits	284	Target Neighborhood Hits	1804	Shared Neighborhood Hits	118
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

EHMT2_MOUSE
θ value	0.00390308 (rank : 51)	NC score	0.026140 (rank : 239)
Query Neighborhood Hits	284	Target Neighborhood Hits	750	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MLL3_HUMAN
θ value	0.00509761 (rank : 52)	NC score	0.073746 (rank : 75)
Query Neighborhood Hits	284	Target Neighborhood Hits	1644	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ZN750_MOUSE
θ value	0.00509761 (rank : 53)	NC score	0.071369 (rank : 82)
Query Neighborhood Hits	284	Target Neighborhood Hits	346	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

NCOA6_HUMAN
θ value	0.00665767 (rank : 54)	NC score	0.098612 (rank : 43)
Query Neighborhood Hits	284	Target Neighborhood Hits	1202	Shared Neighborhood Hits	141
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

EPN3_HUMAN
θ value	0.00869519 (rank : 55)	NC score	0.058625 (rank : 129)
Query Neighborhood Hits	284	Target Neighborhood Hits	197	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

PHLB1_HUMAN
θ value	0.00869519 (rank : 56)	NC score	0.047851 (rank : 190)
Query Neighborhood Hits	284	Target Neighborhood Hits	1038	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

HRBL_MOUSE
θ value	0.0113563 (rank : 57)	NC score	0.051439 (rank : 171)
Query Neighborhood Hits	284	Target Neighborhood Hits	269	Shared Neighborhood Hits	34
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

MAML1_MOUSE
θ value	0.0113563 (rank : 58)	NC score	0.054067 (rank : 152)
Query Neighborhood Hits	284	Target Neighborhood Hits	279	Shared Neighborhood Hits	44
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

CBP_HUMAN
θ value	0.0193708 (rank : 59)	NC score	0.072365 (rank : 79)
Query Neighborhood Hits	284	Target Neighborhood Hits	941	Shared Neighborhood Hits	122
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NCOA2_HUMAN
θ value	0.0193708 (rank : 60)	NC score	0.049703 (rank : 183)
Query Neighborhood Hits	284	Target Neighborhood Hits	281	Shared Neighborhood Hits	35
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PHLB1_MOUSE
θ value	0.0193708 (rank : 61)	NC score	0.050488 (rank : 177)
Query Neighborhood Hits	284	Target Neighborhood Hits	678	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

ZN516_MOUSE
θ value	0.0193708 (rank : 62)	NC score	0.016974 (rank : 281)
Query Neighborhood Hits	284	Target Neighborhood Hits	1197	Shared Neighborhood Hits	77
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

BSN_MOUSE
θ value	0.0252991 (rank : 63)	NC score	0.091942 (rank : 48)
Query Neighborhood Hits	284	Target Neighborhood Hits	2057	Shared Neighborhood Hits	168
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

HAIR_HUMAN
θ value	0.0252991 (rank : 64)	NC score	0.048052 (rank : 189)
Query Neighborhood Hits	284	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

PK1L1_HUMAN
θ value	0.0252991 (rank : 65)	NC score	0.038400 (rank : 206)
Query Neighborhood Hits	284	Target Neighborhood Hits	140	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PRRT3_HUMAN
θ value	0.0252991 (rank : 66)	NC score	0.093790 (rank : 47)
Query Neighborhood Hits	284	Target Neighborhood Hits	998	Shared Neighborhood Hits	102
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

STK10_HUMAN
θ value	0.0252991 (rank : 67)	NC score	0.013076 (rank : 304)
Query Neighborhood Hits	284	Target Neighborhood Hits	1921	Shared Neighborhood Hits	60
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

PAK4_MOUSE
θ value	0.0330416 (rank : 68)	NC score	0.015133 (rank : 293)
Query Neighborhood Hits	284	Target Neighborhood Hits	1098	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

CBL_HUMAN
θ value	0.0431538 (rank : 69)	NC score	0.043883 (rank : 200)
Query Neighborhood Hits	284	Target Neighborhood Hits	353	Shared Neighborhood Hits	28
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CO5A2_HUMAN
θ value	0.0431538 (rank : 70)	NC score	0.034447 (rank : 216)
Query Neighborhood Hits	284	Target Neighborhood Hits	760	Shared Neighborhood Hits	92
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

GRIN1_HUMAN
θ value	0.0431538 (rank : 71)	NC score	0.058956 (rank : 126)
Query Neighborhood Hits	284	Target Neighborhood Hits	681	Shared Neighborhood Hits	77
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NFH_MOUSE
θ value	0.0431538 (rank : 72)	NC score	0.053192 (rank : 156)
Query Neighborhood Hits	284	Target Neighborhood Hits	2247	Shared Neighborhood Hits	138
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PER3_HUMAN
θ value	0.0431538 (rank : 73)	NC score	0.042137 (rank : 201)
Query Neighborhood Hits	284	Target Neighborhood Hits	479	Shared Neighborhood Hits	68
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

JPH2_HUMAN
θ value	0.0563607 (rank : 74)	NC score	0.049674 (rank : 184)
Query Neighborhood Hits	284	Target Neighborhood Hits	639	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

NCOA2_MOUSE
θ value	0.0563607 (rank : 75)	NC score	0.036159 (rank : 212)
Query Neighborhood Hits	284	Target Neighborhood Hits	281	Shared Neighborhood Hits	40
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOR2_MOUSE
θ value	0.0563607 (rank : 76)	NC score	0.061802 (rank : 108)
Query Neighborhood Hits	284	Target Neighborhood Hits	790	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PI5PA_HUMAN
θ value	0.0563607 (rank : 77)	NC score	0.071815 (rank : 81)
Query Neighborhood Hits	284	Target Neighborhood Hits	749	Shared Neighborhood Hits	113
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BCL9_HUMAN
θ value	0.0736092 (rank : 78)	NC score	0.091891 (rank : 49)
Query Neighborhood Hits	284	Target Neighborhood Hits	1008	Shared Neighborhood Hits	104
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CIC_HUMAN
θ value	0.0736092 (rank : 79)	NC score	0.074873 (rank : 72)
Query Neighborhood Hits	284	Target Neighborhood Hits	992	Shared Neighborhood Hits	145
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DIDO1_HUMAN
θ value	0.0736092 (rank : 80)	NC score	0.058424 (rank : 131)
Query Neighborhood Hits	284	Target Neighborhood Hits	960	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SF3B1_HUMAN
θ value	0.0961366 (rank : 81)	NC score	0.056478 (rank : 139)
Query Neighborhood Hits	284	Target Neighborhood Hits	341	Shared Neighborhood Hits	43
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.0961366 (rank : 82)	NC score	0.056444 (rank : 140)
Query Neighborhood Hits	284	Target Neighborhood Hits	352	Shared Neighborhood Hits	44
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TGON2_HUMAN
θ value	0.0961366 (rank : 83)	NC score	0.053400 (rank : 154)
Query Neighborhood Hits	284	Target Neighborhood Hits	1037	Shared Neighborhood Hits	83
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CECR2_HUMAN
θ value	0.125558 (rank : 84)	NC score	0.047398 (rank : 193)
Query Neighborhood Hits	284	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

GNAS1_HUMAN
θ value	0.125558 (rank : 85)	NC score	0.033673 (rank : 220)
Query Neighborhood Hits	284	Target Neighborhood Hits	278	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

MUCDL_HUMAN
θ value	0.125558 (rank : 86)	NC score	0.068097 (rank : 91)
Query Neighborhood Hits	284	Target Neighborhood Hits	777	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYCD_MOUSE
θ value	0.125558 (rank : 87)	NC score	0.033915 (rank : 219)
Query Neighborhood Hits	284	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

SC6A5_MOUSE
θ value	0.125558 (rank : 88)	NC score	0.016483 (rank : 282)
Query Neighborhood Hits	284	Target Neighborhood Hits	135	Shared Neighborhood Hits	20
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

MARK2_HUMAN
θ value	0.163984 (rank : 89)	NC score	0.015119 (rank : 294)
Query Neighborhood Hits	284	Target Neighborhood Hits	1056	Shared Neighborhood Hits	51
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

PUNC_MOUSE
θ value	0.163984 (rank : 90)	NC score	0.012638 (rank : 307)
Query Neighborhood Hits	284	Target Neighborhood Hits	501	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

S23IP_MOUSE
θ value	0.163984 (rank : 91)	NC score	0.050995 (rank : 174)
Query Neighborhood Hits	284	Target Neighborhood Hits	363	Shared Neighborhood Hits	56
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

ULK1_HUMAN
θ value	0.163984 (rank : 92)	NC score	0.016333 (rank : 284)
Query Neighborhood Hits	284	Target Neighborhood Hits	1121	Shared Neighborhood Hits	68
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ATX7_HUMAN
θ value	0.21417 (rank : 93)	NC score	0.038972 (rank : 205)
Query Neighborhood Hits	284	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CEP68_HUMAN
θ value	0.21417 (rank : 94)	NC score	0.047411 (rank : 192)
Query Neighborhood Hits	284	Target Neighborhood Hits	128	Shared Neighborhood Hits	27
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CRSP2_HUMAN
θ value	0.21417 (rank : 95)	NC score	0.062749 (rank : 102)
Query Neighborhood Hits	284	Target Neighborhood Hits	380	Shared Neighborhood Hits	64
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

MKL1_MOUSE
θ value	0.21417 (rank : 96)	NC score	0.051992 (rank : 169)
Query Neighborhood Hits	284	Target Neighborhood Hits	667	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

R3HD2_MOUSE
θ value	0.21417 (rank : 97)	NC score	0.068165 (rank : 90)
Query Neighborhood Hits	284	Target Neighborhood Hits	397	Shared Neighborhood Hits	60
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RUNX1_HUMAN
θ value	0.21417 (rank : 98)	NC score	0.028502 (rank : 233)
Query Neighborhood Hits	284	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

CT152_MOUSE
θ value	0.279714 (rank : 99)	NC score	0.164023 (rank : 38)
Query Neighborhood Hits	284	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

GLI2_HUMAN
θ value	0.279714 (rank : 100)	NC score	0.004694 (rank : 347)
Query Neighborhood Hits	284	Target Neighborhood Hits	971	Shared Neighborhood Hits	48
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

KCD18_HUMAN
θ value	0.279714 (rank : 101)	NC score	0.023312 (rank : 249)
Query Neighborhood Hits	284	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

NU133_HUMAN
θ value	0.279714 (rank : 102)	NC score	0.029171 (rank : 230)
Query Neighborhood Hits	284	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

RXRA_HUMAN
θ value	0.279714 (rank : 103)	NC score	0.005891 (rank : 339)
Query Neighborhood Hits	284	Target Neighborhood Hits	223	Shared Neighborhood Hits	17
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

CAC1G_HUMAN
θ value	0.365318 (rank : 104)	NC score	0.038139 (rank : 208)
Query Neighborhood Hits	284	Target Neighborhood Hits	587	Shared Neighborhood Hits	61
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DCNP1_HUMAN
θ value	0.365318 (rank : 105)	NC score	0.048527 (rank : 187)
Query Neighborhood Hits	284	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF63	Gene names	DCNP1, C5orf20
Domain Architecture	No domain graphic available
Description	Dendritic cell nuclear protein 1.

EPN3_MOUSE
θ value	0.365318 (rank : 106)	NC score	0.050279 (rank : 178)
Query Neighborhood Hits	284	Target Neighborhood Hits	312	Shared Neighborhood Hits	53
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

MEF2D_HUMAN
θ value	0.365318 (rank : 107)	NC score	0.046993 (rank : 194)
Query Neighborhood Hits	284	Target Neighborhood Hits	170	Shared Neighborhood Hits	39
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MILK1_MOUSE
θ value	0.365318 (rank : 108)	NC score	0.056212 (rank : 144)
Query Neighborhood Hits	284	Target Neighborhood Hits	788	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MLL3_MOUSE
θ value	0.365318 (rank : 109)	NC score	0.060085 (rank : 119)
Query Neighborhood Hits	284	Target Neighborhood Hits	1399	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

OGFR_HUMAN
θ value	0.365318 (rank : 110)	NC score	0.082456 (rank : 64)
Query Neighborhood Hits	284	Target Neighborhood Hits	1582	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

DOCK4_MOUSE
θ value	0.47712 (rank : 111)	NC score	0.020904 (rank : 259)
Query Neighborhood Hits	284	Target Neighborhood Hits	210	Shared Neighborhood Hits	32
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MAGD4_HUMAN
θ value	0.47712 (rank : 112)	NC score	0.035396 (rank : 213)
Query Neighborhood Hits	284	Target Neighborhood Hits	338	Shared Neighborhood Hits	52
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MEF2D_MOUSE
θ value	0.47712 (rank : 113)	NC score	0.046328 (rank : 196)
Query Neighborhood Hits	284	Target Neighborhood Hits	146	Shared Neighborhood Hits	42
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MY18B_HUMAN
θ value	0.47712 (rank : 114)	NC score	0.012302 (rank : 311)
Query Neighborhood Hits	284	Target Neighborhood Hits	1299	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CAC1B_MOUSE
θ value	0.62314 (rank : 115)	NC score	0.018406 (rank : 270)
Query Neighborhood Hits	284	Target Neighborhood Hits	351	Shared Neighborhood Hits	47
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1H_HUMAN
θ value	0.62314 (rank : 116)	NC score	0.025642 (rank : 243)
Query Neighborhood Hits	284	Target Neighborhood Hits	307	Shared Neighborhood Hits	43
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CCR3_MOUSE
θ value	0.62314 (rank : 117)	NC score	0.012400 (rank : 310)
Query Neighborhood Hits	284	Target Neighborhood Hits	781	Shared Neighborhood Hits	10
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

CSKI1_MOUSE
θ value	0.62314 (rank : 118)	NC score	0.034206 (rank : 218)
Query Neighborhood Hits	284	Target Neighborhood Hits	1031	Shared Neighborhood Hits	119
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DCC_MOUSE
θ value	0.62314 (rank : 119)	NC score	0.014971 (rank : 295)
Query Neighborhood Hits	284	Target Neighborhood Hits	896	Shared Neighborhood Hits	44
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

JIP1_HUMAN
θ value	0.62314 (rank : 120)	NC score	0.028983 (rank : 232)
Query Neighborhood Hits	284	Target Neighborhood Hits	271	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

KLF17_HUMAN
θ value	0.62314 (rank : 121)	NC score	0.003945 (rank : 349)
Query Neighborhood Hits	284	Target Neighborhood Hits	882	Shared Neighborhood Hits	45
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

MYO1E_HUMAN
θ value	0.62314 (rank : 122)	NC score	0.004926 (rank : 344)
Query Neighborhood Hits	284	Target Neighborhood Hits	293	Shared Neighborhood Hits	11
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

PCLO_MOUSE
θ value	0.62314 (rank : 123)	NC score	0.069109 (rank : 86)
Query Neighborhood Hits	284	Target Neighborhood Hits	2275	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDZD2_HUMAN
θ value	0.62314 (rank : 124)	NC score	0.052077 (rank : 166)
Query Neighborhood Hits	284	Target Neighborhood Hits	772	Shared Neighborhood Hits	68
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RPGF1_HUMAN
θ value	0.62314 (rank : 125)	NC score	0.015561 (rank : 289)
Query Neighborhood Hits	284	Target Neighborhood Hits	262	Shared Neighborhood Hits	14
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

RUSC2_MOUSE
θ value	0.62314 (rank : 126)	NC score	0.038230 (rank : 207)
Query Neighborhood Hits	284	Target Neighborhood Hits	305	Shared Neighborhood Hits	55
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SAPS1_HUMAN
θ value	0.62314 (rank : 127)	NC score	0.068735 (rank : 88)
Query Neighborhood Hits	284	Target Neighborhood Hits	704	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TPO_MOUSE
θ value	0.62314 (rank : 128)	NC score	0.046613 (rank : 195)
Query Neighborhood Hits	284	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

BAT3_MOUSE
θ value	0.813845 (rank : 129)	NC score	0.073342 (rank : 77)
Query Neighborhood Hits	284	Target Neighborhood Hits	518	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

GMEB2_HUMAN
θ value	0.813845 (rank : 130)	NC score	0.021438 (rank : 257)
Query Neighborhood Hits	284	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

MEF2B_MOUSE
θ value	0.813845 (rank : 131)	NC score	0.034654 (rank : 214)
Query Neighborhood Hits	284	Target Neighborhood Hits	218	Shared Neighborhood Hits	28
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MISS_MOUSE
θ value	0.813845 (rank : 132)	NC score	0.068221 (rank : 89)
Query Neighborhood Hits	284	Target Neighborhood Hits	444	Shared Neighborhood Hits	71
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NCOA6_MOUSE
θ value	0.813845 (rank : 133)	NC score	0.076886 (rank : 69)
Query Neighborhood Hits	284	Target Neighborhood Hits	1076	Shared Neighborhood Hits	122
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SPAG1_MOUSE
θ value	0.813845 (rank : 134)	NC score	0.011978 (rank : 312)
Query Neighborhood Hits	284	Target Neighborhood Hits	218	Shared Neighborhood Hits	8
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

SSBP4_HUMAN
θ value	0.813845 (rank : 135)	NC score	0.053377 (rank : 155)
Query Neighborhood Hits	284	Target Neighborhood Hits	753	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TLE1_HUMAN
θ value	0.813845 (rank : 136)	NC score	0.014913 (rank : 297)
Query Neighborhood Hits	284	Target Neighborhood Hits	485	Shared Neighborhood Hits	27
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TRIM8_HUMAN
θ value	0.813845 (rank : 137)	NC score	0.013275 (rank : 302)
Query Neighborhood Hits	284	Target Neighborhood Hits	650	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ULK1_MOUSE
θ value	0.813845 (rank : 138)	NC score	0.016338 (rank : 283)
Query Neighborhood Hits	284	Target Neighborhood Hits	1214	Shared Neighborhood Hits	73
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

AFF2_MOUSE
θ value	1.06291 (rank : 139)	NC score	0.028154 (rank : 234)
Query Neighborhood Hits	284	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

B4GT1_HUMAN
θ value	1.06291 (rank : 140)	NC score	0.020739 (rank : 260)
Query Neighborhood Hits	284	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

BPTF_HUMAN
θ value	1.06291 (rank : 141)	NC score	0.029699 (rank : 227)
Query Neighborhood Hits	284	Target Neighborhood Hits	786	Shared Neighborhood Hits	62
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CBP_MOUSE
θ value	1.06291 (rank : 142)	NC score	0.064155 (rank : 97)
Query Neighborhood Hits	284	Target Neighborhood Hits	1051	Shared Neighborhood Hits	122
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DDX24_MOUSE
θ value	1.06291 (rank : 143)	NC score	0.004814 (rank : 346)
Query Neighborhood Hits	284	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

GRIN1_MOUSE
θ value	1.06291 (rank : 144)	NC score	0.056770 (rank : 138)
Query Neighborhood Hits	284	Target Neighborhood Hits	337	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

K0056_HUMAN
θ value	1.06291 (rank : 145)	NC score	0.025526 (rank : 244)
Query Neighborhood Hits	284	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

SC24C_HUMAN
θ value	1.06291 (rank : 146)	NC score	0.074014 (rank : 74)
Query Neighborhood Hits	284	Target Neighborhood Hits	662	Shared Neighborhood Hits	93
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TAU_HUMAN
θ value	1.06291 (rank : 147)	NC score	0.050652 (rank : 176)
Query Neighborhood Hits	284	Target Neighborhood Hits	448	Shared Neighborhood Hits	74
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TRIM8_MOUSE
θ value	1.06291 (rank : 148)	NC score	0.011609 (rank : 315)
Query Neighborhood Hits	284	Target Neighborhood Hits	674	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

CSPG5_MOUSE
θ value	1.38821 (rank : 149)	NC score	0.022384 (rank : 253)
Query Neighborhood Hits	284	Target Neighborhood Hits	211	Shared Neighborhood Hits	16
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CT174_HUMAN
θ value	1.38821 (rank : 150)	NC score	0.048238 (rank : 188)
Query Neighborhood Hits	284	Target Neighborhood Hits	181	Shared Neighborhood Hits	35
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DOCK4_HUMAN
θ value	1.38821 (rank : 151)	NC score	0.019492 (rank : 264)
Query Neighborhood Hits	284	Target Neighborhood Hits	237	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

RFIP5_MOUSE
θ value	1.38821 (rank : 152)	NC score	0.017228 (rank : 280)
Query Neighborhood Hits	284	Target Neighborhood Hits	126	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

SQSTM_HUMAN
θ value	1.38821 (rank : 153)	NC score	0.018801 (rank : 266)
Query Neighborhood Hits	284	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).

XKR7_MOUSE
θ value	1.38821 (rank : 154)	NC score	0.020647 (rank : 262)
Query Neighborhood Hits	284	Target Neighborhood Hits	146	Shared Neighborhood Hits	14
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

ZDH14_HUMAN
θ value	1.38821 (rank : 155)	NC score	0.011403 (rank : 317)
Query Neighborhood Hits	284	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZN3, Q5JS07, Q5JS08, Q6PHS4, Q8IZN2, Q9H7F1	Gene names	ZDHHC14
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP).

ZFY28_HUMAN
θ value	1.38821 (rank : 156)	NC score	0.012841 (rank : 305)
Query Neighborhood Hits	284	Target Neighborhood Hits	152	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZN687_HUMAN
θ value	1.38821 (rank : 157)	NC score	0.017930 (rank : 273)
Query Neighborhood Hits	284	Target Neighborhood Hits	1244	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CI079_HUMAN
θ value	1.81305 (rank : 158)	NC score	0.044983 (rank : 198)
Query Neighborhood Hits	284	Target Neighborhood Hits	288	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CO7A1_HUMAN
θ value	1.81305 (rank : 159)	NC score	0.021889 (rank : 254)
Query Neighborhood Hits	284	Target Neighborhood Hits	807	Shared Neighborhood Hits	82
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DOT1L_HUMAN
θ value	1.81305 (rank : 160)	NC score	0.077443 (rank : 68)
Query Neighborhood Hits	284	Target Neighborhood Hits	660	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

M3K9_HUMAN
θ value	1.81305 (rank : 161)	NC score	0.007753 (rank : 331)
Query Neighborhood Hits	284	Target Neighborhood Hits	1123	Shared Neighborhood Hits	43
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MINT_MOUSE
θ value	1.81305 (rank : 162)	NC score	0.045854 (rank : 197)
Query Neighborhood Hits	284	Target Neighborhood Hits	1514	Shared Neighborhood Hits	98
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOR2_HUMAN
θ value	1.81305 (rank : 163)	NC score	0.060934 (rank : 114)
Query Neighborhood Hits	284	Target Neighborhood Hits	870	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NRX2A_HUMAN
θ value	1.81305 (rank : 164)	NC score	0.027442 (rank : 235)
Query Neighborhood Hits	284	Target Neighborhood Hits	614	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.81305 (rank : 165)	NC score	0.042015 (rank : 202)
Query Neighborhood Hits	284	Target Neighborhood Hits	481	Shared Neighborhood Hits	48
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PGCA_MOUSE
θ value	1.81305 (rank : 166)	NC score	0.020726 (rank : 261)
Query Neighborhood Hits	284	Target Neighborhood Hits	643	Shared Neighborhood Hits	48
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PHLPP_HUMAN
θ value	1.81305 (rank : 167)	NC score	0.026640 (rank : 237)
Query Neighborhood Hits	284	Target Neighborhood Hits	604	Shared Neighborhood Hits	57
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

S5A2_HUMAN
θ value	1.81305 (rank : 168)	NC score	0.026444 (rank : 238)
Query Neighborhood Hits	284	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P31213, Q9BYE6	Gene names	SRD5A2
Domain Architecture
Description	3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5) (Steroid 5- alpha-reductase 2) (SR type 2) (5 alpha-SR2) (Type II 5-alpha reductase).

SOX13_MOUSE
θ value	1.81305 (rank : 169)	NC score	0.017636 (rank : 278)
Query Neighborhood Hits	284	Target Neighborhood Hits	495	Shared Neighborhood Hits	34
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

AATK_HUMAN
θ value	2.36792 (rank : 170)	NC score	0.013492 (rank : 301)
Query Neighborhood Hits	284	Target Neighborhood Hits	1243	Shared Neighborhood Hits	89
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

BAI2_HUMAN
θ value	2.36792 (rank : 171)	NC score	0.003343 (rank : 353)
Query Neighborhood Hits	284	Target Neighborhood Hits	332	Shared Neighborhood Hits	18
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAT3_HUMAN
θ value	2.36792 (rank : 172)	NC score	0.060330 (rank : 117)
Query Neighborhood Hits	284	Target Neighborhood Hits	490	Shared Neighborhood Hits	71
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BCL9_MOUSE
θ value	2.36792 (rank : 173)	NC score	0.083094 (rank : 63)
Query Neighborhood Hits	284	Target Neighborhood Hits	770	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CEL_HUMAN
θ value	2.36792 (rank : 174)	NC score	0.032704 (rank : 225)
Query Neighborhood Hits	284	Target Neighborhood Hits	896	Shared Neighborhood Hits	90
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FA8A1_HUMAN
θ value	2.36792 (rank : 175)	NC score	0.062870 (rank : 100)
Query Neighborhood Hits	284	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

HCFC1_HUMAN
θ value	2.36792 (rank : 176)	NC score	0.029179 (rank : 229)
Query Neighborhood Hits	284	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HTRA4_HUMAN
θ value	2.36792 (rank : 177)	NC score	0.033214 (rank : 224)
Query Neighborhood Hits	284	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

IF4G1_MOUSE
θ value	2.36792 (rank : 178)	NC score	0.037976 (rank : 209)
Query Neighborhood Hits	284	Target Neighborhood Hits	534	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

NOTC3_HUMAN
θ value	2.36792 (rank : 179)	NC score	0.003375 (rank : 352)
Query Neighborhood Hits	284	Target Neighborhood Hits	1062	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PO3F4_HUMAN
θ value	2.36792 (rank : 180)	NC score	0.002995 (rank : 354)
Query Neighborhood Hits	284	Target Neighborhood Hits	297	Shared Neighborhood Hits	8
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

RUNX1_MOUSE
θ value	2.36792 (rank : 181)	NC score	0.026035 (rank : 241)
Query Neighborhood Hits	284	Target Neighborhood Hits	93	Shared Neighborhood Hits	20
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

SC24A_MOUSE
θ value	2.36792 (rank : 182)	NC score	0.043909 (rank : 199)
Query Neighborhood Hits	284	Target Neighborhood Hits	394	Shared Neighborhood Hits	63
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SPEG_MOUSE
θ value	2.36792 (rank : 183)	NC score	0.022953 (rank : 251)
Query Neighborhood Hits	284	Target Neighborhood Hits	1959	Shared Neighborhood Hits	134
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UBP6_HUMAN
θ value	2.36792 (rank : 184)	NC score	0.011648 (rank : 314)
Query Neighborhood Hits	284	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

CAMKV_HUMAN
θ value	3.0926 (rank : 185)	NC score	0.015550 (rank : 290)
Query Neighborhood Hits	284	Target Neighborhood Hits	1084	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CT152_HUMAN
θ value	3.0926 (rank : 186)	NC score	0.097353 (rank : 44)
Query Neighborhood Hits	284	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

CUTL1_MOUSE
θ value	3.0926 (rank : 187)	NC score	0.011267 (rank : 318)
Query Neighborhood Hits	284	Target Neighborhood Hits	1620	Shared Neighborhood Hits	65
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

FOG1_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.015923 (rank : 287)
Query Neighborhood Hits	284	Target Neighborhood Hits	1237	Shared Neighborhood Hits	91
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FREA_HUMAN
θ value	3.0926 (rank : 189)	NC score	0.006299 (rank : 336)
Query Neighborhood Hits	284	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

HSF4_MOUSE
θ value	3.0926 (rank : 190)	NC score	0.008300 (rank : 326)
Query Neighborhood Hits	284	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0L1, Q9R0L2	Gene names	Hsf4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (mHSF4).

IRS2_MOUSE
θ value	3.0926 (rank : 191)	NC score	0.034288 (rank : 217)
Query Neighborhood Hits	284	Target Neighborhood Hits	248	Shared Neighborhood Hits	66
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MAML2_HUMAN
θ value	3.0926 (rank : 192)	NC score	0.034650 (rank : 215)
Query Neighborhood Hits	284	Target Neighborhood Hits	360	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

PP14A_MOUSE
θ value	3.0926 (rank : 193)	NC score	0.037222 (rank : 210)
Query Neighborhood Hits	284	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VC7, Q99MB9	Gene names	Ppp1r14a, Cpi17
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (CPI-17).

RUNX3_HUMAN
θ value	3.0926 (rank : 194)	NC score	0.033233 (rank : 223)
Query Neighborhood Hits	284	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX3_MOUSE
θ value	3.0926 (rank : 195)	NC score	0.033577 (rank : 222)
Query Neighborhood Hits	284	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SALL2_MOUSE
θ value	3.0926 (rank : 196)	NC score	0.004898 (rank : 345)
Query Neighborhood Hits	284	Target Neighborhood Hits	836	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

SON_HUMAN
θ value	3.0926 (rank : 197)	NC score	0.052220 (rank : 165)
Query Neighborhood Hits	284	Target Neighborhood Hits	1568	Shared Neighborhood Hits	120
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

T22D4_HUMAN
θ value	3.0926 (rank : 198)	NC score	0.051339 (rank : 172)
Query Neighborhood Hits	284	Target Neighborhood Hits	403	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TARA_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.048743 (rank : 186)
Query Neighborhood Hits	284	Target Neighborhood Hits	1626	Shared Neighborhood Hits	110
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	3.0926 (rank : 200)	NC score	0.052908 (rank : 161)
Query Neighborhood Hits	284	Target Neighborhood Hits	768	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TLE1_MOUSE
θ value	3.0926 (rank : 201)	NC score	0.015202 (rank : 292)
Query Neighborhood Hits	284	Target Neighborhood Hits	491	Shared Neighborhood Hits	30
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ZIMP7_MOUSE
θ value	3.0926 (rank : 202)	NC score	0.040356 (rank : 203)
Query Neighborhood Hits	284	Target Neighborhood Hits	566	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN217_HUMAN
θ value	3.0926 (rank : 203)	NC score	0.001799 (rank : 357)
Query Neighborhood Hits	284	Target Neighborhood Hits	905	Shared Neighborhood Hits	40
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

AMPH_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.024423 (rank : 246)
Query Neighborhood Hits	284	Target Neighborhood Hits	455	Shared Neighborhood Hits	43
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

B3A3_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.009729 (rank : 322)
Query Neighborhood Hits	284	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

CD248_MOUSE
θ value	4.03905 (rank : 206)	NC score	0.021610 (rank : 255)
Query Neighborhood Hits	284	Target Neighborhood Hits	578	Shared Neighborhood Hits	47
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CRTC1_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.051523 (rank : 170)
Query Neighborhood Hits	284	Target Neighborhood Hits	319	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

GAB2_MOUSE
θ value	4.03905 (rank : 208)	NC score	0.015791 (rank : 288)
Query Neighborhood Hits	284	Target Neighborhood Hits	220	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GAK11_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.018678 (rank : 268)
Query Neighborhood Hits	284	Target Neighborhood Hits	409	Shared Neighborhood Hits	38
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	4.03905 (rank : 210)	NC score	0.019026 (rank : 265)
Query Neighborhood Hits	284	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	4.03905 (rank : 211)	NC score	0.018789 (rank : 267)
Query Neighborhood Hits	284	Target Neighborhood Hits	415	Shared Neighborhood Hits	39
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	4.03905 (rank : 212)	NC score	0.018475 (rank : 269)
Query Neighborhood Hits	284	Target Neighborhood Hits	429	Shared Neighborhood Hits	37
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	4.03905 (rank : 213)	NC score	0.018241 (rank : 271)
Query Neighborhood Hits	284	Target Neighborhood Hits	392	Shared Neighborhood Hits	38
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GLIS3_MOUSE
θ value	4.03905 (rank : 214)	NC score	0.001007 (rank : 359)
Query Neighborhood Hits	284	Target Neighborhood Hits	861	Shared Neighborhood Hits	41
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

GP123_HUMAN
θ value	4.03905 (rank : 215)	NC score	0.006798 (rank : 333)
Query Neighborhood Hits	284	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

HCFC1_MOUSE
θ value	4.03905 (rank : 216)	NC score	0.029015 (rank : 231)
Query Neighborhood Hits	284	Target Neighborhood Hits	348	Shared Neighborhood Hits	37
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

IQEC3_MOUSE
θ value	4.03905 (rank : 217)	NC score	0.023101 (rank : 250)
Query Neighborhood Hits	284	Target Neighborhood Hits	274	Shared Neighborhood Hits	45
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MAVS_HUMAN
θ value	4.03905 (rank : 218)	NC score	0.047822 (rank : 191)
Query Neighborhood Hits	284	Target Neighborhood Hits	271	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MLL2_HUMAN
θ value	4.03905 (rank : 219)	NC score	0.070720 (rank : 83)
Query Neighborhood Hits	284	Target Neighborhood Hits	1788	Shared Neighborhood Hits	163
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RB_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.012566 (rank : 308)
Query Neighborhood Hits	284	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P06400, P78499, Q5VW46, Q8IZL4	Gene names	RB1
Domain Architecture
Description	Retinoblastoma-associated protein (PP110) (P105-RB) (RB).

RIPK1_MOUSE
θ value	4.03905 (rank : 221)	NC score	0.006679 (rank : 334)
Query Neighborhood Hits	284	Target Neighborhood Hits	874	Shared Neighborhood Hits	26
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

SEM6C_MOUSE
θ value	4.03905 (rank : 222)	NC score	0.019527 (rank : 263)
Query Neighborhood Hits	284	Target Neighborhood Hits	352	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SNPC4_MOUSE
θ value	4.03905 (rank : 223)	NC score	0.016017 (rank : 285)
Query Neighborhood Hits	284	Target Neighborhood Hits	237	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SRRM1_MOUSE
θ value	4.03905 (rank : 224)	NC score	0.087405 (rank : 53)
Query Neighborhood Hits	284	Target Neighborhood Hits	966	Shared Neighborhood Hits	128
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

STK10_MOUSE
θ value	4.03905 (rank : 225)	NC score	0.013251 (rank : 303)
Query Neighborhood Hits	284	Target Neighborhood Hits	2132	Shared Neighborhood Hits	64
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TAAR1_HUMAN
θ value	4.03905 (rank : 226)	NC score	-0.000142 (rank : 360)
Query Neighborhood Hits	284	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

TBX2_HUMAN
θ value	4.03905 (rank : 227)	NC score	0.008631 (rank : 325)
Query Neighborhood Hits	284	Target Neighborhood Hits	195	Shared Neighborhood Hits	26
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TSH3_HUMAN
θ value	4.03905 (rank : 228)	NC score	0.005921 (rank : 338)
Query Neighborhood Hits	284	Target Neighborhood Hits	564	Shared Neighborhood Hits	21
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

US6NL_HUMAN
θ value	4.03905 (rank : 229)	NC score	0.014955 (rank : 296)
Query Neighborhood Hits	284	Target Neighborhood Hits	201	Shared Neighborhood Hits	24
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

ZIMP7_HUMAN
θ value	4.03905 (rank : 230)	NC score	0.026989 (rank : 236)
Query Neighborhood Hits	284	Target Neighborhood Hits	290	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ARNT_MOUSE
θ value	5.27518 (rank : 231)	NC score	0.015945 (rank : 286)
Query Neighborhood Hits	284	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ASPX_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.014095 (rank : 298)
Query Neighborhood Hits	284	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

CAC1H_MOUSE
θ value	5.27518 (rank : 233)	NC score	0.018068 (rank : 272)
Query Neighborhood Hits	284	Target Neighborhood Hits	230	Shared Neighborhood Hits	31
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CLAP2_MOUSE
θ value	5.27518 (rank : 234)	NC score	0.008079 (rank : 327)
Query Neighborhood Hits	284	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

DMRTD_HUMAN
θ value	5.27518 (rank : 235)	NC score	0.025264 (rank : 245)
Query Neighborhood Hits	284	Target Neighborhood Hits	216	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

EDD1_MOUSE
θ value	5.27518 (rank : 236)	NC score	0.005184 (rank : 343)
Query Neighborhood Hits	284	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

ELF4_MOUSE
θ value	5.27518 (rank : 237)	NC score	0.009473 (rank : 323)
Query Neighborhood Hits	284	Target Neighborhood Hits	191	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

F100B_MOUSE
θ value	5.27518 (rank : 238)	NC score	0.022408 (rank : 252)
Query Neighborhood Hits	284	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

INVS_MOUSE
θ value	5.27518 (rank : 239)	NC score	0.017908 (rank : 275)
Query Neighborhood Hits	284	Target Neighborhood Hits	609	Shared Neighborhood Hits	51
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

LIMD1_MOUSE
θ value	5.27518 (rank : 240)	NC score	0.012464 (rank : 309)
Query Neighborhood Hits	284	Target Neighborhood Hits	291	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MAGC1_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.025712 (rank : 242)
Query Neighborhood Hits	284	Target Neighborhood Hits	431	Shared Neighborhood Hits	72
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MARK2_MOUSE
θ value	5.27518 (rank : 242)	NC score	0.012802 (rank : 306)
Query Neighborhood Hits	284	Target Neighborhood Hits	1018	Shared Neighborhood Hits	52
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

NFIB_HUMAN
θ value	5.27518 (rank : 243)	NC score	0.006560 (rank : 335)
Query Neighborhood Hits	284	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PAPPA_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.006856 (rank : 332)
Query Neighborhood Hits	284	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PYR1_HUMAN
θ value	5.27518 (rank : 245)	NC score	0.017640 (rank : 277)
Query Neighborhood Hits	284	Target Neighborhood Hits	119	Shared Neighborhood Hits	17
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

RGS3_HUMAN
θ value	5.27518 (rank : 246)	NC score	0.061755 (rank : 109)
Query Neighborhood Hits	284	Target Neighborhood Hits	1375	Shared Neighborhood Hits	95
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RP3A_MOUSE
θ value	5.27518 (rank : 247)	NC score	0.026089 (rank : 240)
Query Neighborhood Hits	284	Target Neighborhood Hits	510	Shared Neighborhood Hits	67
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SALL2_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.002444 (rank : 355)
Query Neighborhood Hits	284	Target Neighborhood Hits	835	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

WEE1B_HUMAN
θ value	5.27518 (rank : 249)	NC score	0.010914 (rank : 320)
Query Neighborhood Hits	284	Target Neighborhood Hits	836	Shared Neighborhood Hits	37
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

ACINU_MOUSE
θ value	6.88961 (rank : 250)	NC score	0.024356 (rank : 247)
Query Neighborhood Hits	284	Target Neighborhood Hits	712	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AL2S4_MOUSE
θ value	6.88961 (rank : 251)	NC score	0.021476 (rank : 256)
Query Neighborhood Hits	284	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

C1QR1_HUMAN
θ value	6.88961 (rank : 252)	NC score	0.002297 (rank : 356)
Query Neighborhood Hits	284	Target Neighborhood Hits	493	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CLC11_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.006212 (rank : 337)
Query Neighborhood Hits	284	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y240	Gene names	CLEC11A, CLECSF3, LSLCL, SCGF
Domain Architecture
Description	C-type lectin domain family 11 member A precursor (Stem cell growth factor) (Lymphocyte secreted C-type lectin) (p47) (C-type lectin superfamily member 3).

COE3_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.003729 (rank : 351)
Query Neighborhood Hits	284	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

CSKI1_HUMAN
θ value	6.88961 (rank : 255)	NC score	0.036583 (rank : 211)
Query Neighborhood Hits	284	Target Neighborhood Hits	997	Shared Neighborhood Hits	125
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CU058_HUMAN
θ value	6.88961 (rank : 256)	NC score	0.017756 (rank : 276)
Query Neighborhood Hits	284	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P58505	Gene names	C21orf58
Domain Architecture	No domain graphic available
Description	Protein C21orf58.

FILA_HUMAN
θ value	6.88961 (rank : 257)	NC score	0.013889 (rank : 300)
Query Neighborhood Hits	284	Target Neighborhood Hits	685	Shared Neighborhood Hits	38
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FOXN4_MOUSE
θ value	6.88961 (rank : 258)	NC score	0.007800 (rank : 330)
Query Neighborhood Hits	284	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

FYB_HUMAN
θ value	6.88961 (rank : 259)	NC score	0.031940 (rank : 226)
Query Neighborhood Hits	284	Target Neighborhood Hits	379	Shared Neighborhood Hits	50
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GAK2_HUMAN
θ value	6.88961 (rank : 260)	NC score	0.017368 (rank : 279)
Query Neighborhood Hits	284	Target Neighborhood Hits	406	Shared Neighborhood Hits	36
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GNAS1_MOUSE
θ value	6.88961 (rank : 261)	NC score	0.033603 (rank : 221)
Query Neighborhood Hits	284	Target Neighborhood Hits	651	Shared Neighborhood Hits	85
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GPS2_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.021032 (rank : 258)
Query Neighborhood Hits	284	Target Neighborhood Hits	459	Shared Neighborhood Hits	24
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

HIC1_HUMAN
θ value	6.88961 (rank : 263)	NC score	-0.002338 (rank : 362)
Query Neighborhood Hits	284	Target Neighborhood Hits	838	Shared Neighborhood Hits	43
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HXB3_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.003793 (rank : 350)
Query Neighborhood Hits	284	Target Neighborhood Hits	559	Shared Neighborhood Hits	31
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

KCNK1_MOUSE
θ value	6.88961 (rank : 265)	NC score	0.039210 (rank : 204)
Query Neighborhood Hits	284	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

NOTC2_MOUSE
θ value	6.88961 (rank : 266)	NC score	0.001579 (rank : 358)
Query Neighborhood Hits	284	Target Neighborhood Hits	1069	Shared Neighborhood Hits	42
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TACC1_MOUSE
θ value	6.88961 (rank : 267)	NC score	0.007886 (rank : 328)
Query Neighborhood Hits	284	Target Neighborhood Hits	667	Shared Neighborhood Hits	28
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

AFF2_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.017919 (rank : 274)
Query Neighborhood Hits	284	Target Neighborhood Hits	218	Shared Neighborhood Hits	24
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

CABIN_HUMAN
θ value	8.99809 (rank : 269)	NC score	0.052628 (rank : 163)
Query Neighborhood Hits	284	Target Neighborhood Hits	490	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CN037_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.010551 (rank : 321)
Query Neighborhood Hits	284	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

CO2_HUMAN
θ value	8.99809 (rank : 271)	NC score	-0.001056 (rank : 361)
Query Neighborhood Hits	284	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CP007_MOUSE
θ value	8.99809 (rank : 272)	NC score	0.015320 (rank : 291)
Query Neighborhood Hits	284	Target Neighborhood Hits	231	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

GAK_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.011672 (rank : 313)
Query Neighborhood Hits	284	Target Neighborhood Hits	1028	Shared Neighborhood Hits	53
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

HIC1_MOUSE
θ value	8.99809 (rank : 274)	NC score	-0.002916 (rank : 363)
Query Neighborhood Hits	284	Target Neighborhood Hits	863	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

ITF2_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.005761 (rank : 341)
Query Neighborhood Hits	284	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.005232 (rank : 342)
Query Neighborhood Hits	284	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

K0999_MOUSE
θ value	8.99809 (rank : 277)	NC score	0.011214 (rank : 319)
Query Neighborhood Hits	284	Target Neighborhood Hits	931	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

M3K3_MOUSE
θ value	8.99809 (rank : 278)	NC score	0.008999 (rank : 324)
Query Neighborhood Hits	284	Target Neighborhood Hits	876	Shared Neighborhood Hits	26
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

NFAC2_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.007831 (rank : 329)
Query Neighborhood Hits	284	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

PANK1_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.005830 (rank : 340)
Query Neighborhood Hits	284	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

PKN3_MOUSE
θ value	8.99809 (rank : 281)	NC score	0.013976 (rank : 299)
Query Neighborhood Hits	284	Target Neighborhood Hits	1009	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

STML1_MOUSE
θ value	8.99809 (rank : 282)	NC score	0.004425 (rank : 348)
Query Neighborhood Hits	284	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CI66, Q8BLA3	Gene names	Stoml1
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1).

TSH1_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.011541 (rank : 316)
Query Neighborhood Hits	284	Target Neighborhood Hits	675	Shared Neighborhood Hits	23
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

YETS2_MOUSE
θ value	8.99809 (rank : 284)	NC score	0.023604 (rank : 248)
Query Neighborhood Hits	284	Target Neighborhood Hits	278	Shared Neighborhood Hits	45
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ALEX_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.062116 (rank : 106)
Query Neighborhood Hits	284	Target Neighborhood Hits	361	Shared Neighborhood Hits	82
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ATN1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.073717 (rank : 76)
Query Neighborhood Hits	284	Target Neighborhood Hits	676	Shared Neighborhood Hits	128
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BASP_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.055321 (rank : 146)
Query Neighborhood Hits	284	Target Neighborhood Hits	321	Shared Neighborhood Hits	56
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.053149 (rank : 157)
Query Neighborhood Hits	284	Target Neighborhood Hits	260	Shared Neighborhood Hits	41
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.070166 (rank : 84)
Query Neighborhood Hits	284	Target Neighborhood Hits	931	Shared Neighborhood Hits	131
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.058076 (rank : 133)
Query Neighborhood Hits	284	Target Neighborhood Hits	947	Shared Neighborhood Hits	124
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.072091 (rank : 80)
Query Neighborhood Hits	284	Target Neighborhood Hits	1537	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CGRE1_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.052950 (rank : 160)
Query Neighborhood Hits	284	Target Neighborhood Hits	354	Shared Neighborhood Hits	32
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CIC_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.056418 (rank : 141)
Query Neighborhood Hits	284	Target Neighborhood Hits	742	Shared Neighborhood Hits	126
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIZ1_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.052979 (rank : 159)
Query Neighborhood Hits	284	Target Neighborhood Hits	359	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ078_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.060133 (rank : 118)
Query Neighborhood Hits	284	Target Neighborhood Hits	559	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN032_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.075783 (rank : 71)
Query Neighborhood Hits	284	Target Neighborhood Hits	267	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.072794 (rank : 78)
Query Neighborhood Hits	284	Target Neighborhood Hits	233	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CPSF6_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.053579 (rank : 153)
Query Neighborhood Hits	284	Target Neighborhood Hits	359	Shared Neighborhood Hits	85
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.054567 (rank : 149)
Query Neighborhood Hits	284	Target Neighborhood Hits	356	Shared Neighborhood Hits	85
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CS007_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.050170 (rank : 180)
Query Neighborhood Hits	284	Target Neighborhood Hits	464	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS016_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.056321 (rank : 142)
Query Neighborhood Hits	284	Target Neighborhood Hits	310	Shared Neighborhood Hits	71
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

ENAH_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.059455 (rank : 124)
Query Neighborhood Hits	284	Target Neighborhood Hits	919	Shared Neighborhood Hits	130
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.061630 (rank : 111)
Query Neighborhood Hits	284	Target Neighborhood Hits	821	Shared Neighborhood Hits	120
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GGN_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.061659 (rank : 110)
Query Neighborhood Hits	284	Target Neighborhood Hits	269	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.062126 (rank : 105)
Query Neighborhood Hits	284	Target Neighborhood Hits	311	Shared Neighborhood Hits	84
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GSCR1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.094614 (rank : 45)
Query Neighborhood Hits	284	Target Neighborhood Hits	674	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KCNK2_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.061264 (rank : 112)
Query Neighborhood Hits	284	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.060834 (rank : 115)
Query Neighborhood Hits	284	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.058695 (rank : 127)
Query Neighborhood Hits	284	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.057157 (rank : 136)
Query Neighborhood Hits	284	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.054740 (rank : 148)
Query Neighborhood Hits	284	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.059824 (rank : 122)
Query Neighborhood Hits	284	Target Neighborhood Hits	79	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.056320 (rank : 143)
Query Neighborhood Hits	284	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKF_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.062801 (rank : 101)
Query Neighborhood Hits	284	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKG_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.050013 (rank : 182)
Query Neighborhood Hits	284	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.094168 (rank : 46)
Query Neighborhood Hits	284	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

MAML3_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.052573 (rank : 164)
Query Neighborhood Hits	284	Target Neighborhood Hits	323	Shared Neighborhood Hits	45
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MARCS_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.063543 (rank : 99)
Query Neighborhood Hits	284	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MBD6_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.089024 (rank : 50)
Query Neighborhood Hits	284	Target Neighborhood Hits	349	Shared Neighborhood Hits	93
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.051074 (rank : 173)
Query Neighborhood Hits	284	Target Neighborhood Hits	1446	Shared Neighborhood Hits	107
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.059441 (rank : 125)
Query Neighborhood Hits	284	Target Neighborhood Hits	998	Shared Neighborhood Hits	92
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUC1_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.058247 (rank : 132)
Query Neighborhood Hits	284	Target Neighborhood Hits	388	Shared Neighborhood Hits	57
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC7_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.085616 (rank : 55)
Query Neighborhood Hits	284	Target Neighborhood Hits	538	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PCLO_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.059720 (rank : 123)
Query Neighborhood Hits	284	Target Neighborhood Hits	2046	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PI5PA_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.050031 (rank : 181)
Query Neighborhood Hits	284	Target Neighborhood Hits	331	Shared Neighborhood Hits	78
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PO121_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.050229 (rank : 179)
Query Neighborhood Hits	284	Target Neighborhood Hits	344	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PRB3_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.083330 (rank : 62)
Query Neighborhood Hits	284	Target Neighborhood Hits	318	Shared Neighborhood Hits	87
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.081057 (rank : 65)
Query Neighborhood Hits	284	Target Neighborhood Hits	330	Shared Neighborhood Hits	87
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.070043 (rank : 85)
Query Neighborhood Hits	284	Target Neighborhood Hits	764	Shared Neighborhood Hits	113
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.099711 (rank : 42)
Query Neighborhood Hits	284	Target Neighborhood Hits	385	Shared Neighborhood Hits	102
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.111763 (rank : 39)
Query Neighborhood Hits	284	Target Neighborhood Hits	347	Shared Neighborhood Hits	100
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.058571 (rank : 130)
Query Neighborhood Hits	284	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.052053 (rank : 168)
Query Neighborhood Hits	284	Target Neighborhood Hits	165	Shared Neighborhood Hits	51
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRR12_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.068746 (rank : 87)
Query Neighborhood Hits	284	Target Neighborhood Hits	460	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RAPH1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.060647 (rank : 116)
Query Neighborhood Hits	284	Target Neighborhood Hits	593	Shared Neighborhood Hits	118
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RERE_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.057515 (rank : 135)
Query Neighborhood Hits	284	Target Neighborhood Hits	779	Shared Neighborhood Hits	116
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.057812 (rank : 134)
Query Neighborhood Hits	284	Target Neighborhood Hits	785	Shared Neighborhood Hits	130
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RPGF3_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.052071 (rank : 167)
Query Neighborhood Hits	284	Target Neighborhood Hits	54	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

RPGF4_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.062152 (rank : 104)
Query Neighborhood Hits	284	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.064503 (rank : 95)
Query Neighborhood Hits	284	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

SF3A2_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.063965 (rank : 98)
Query Neighborhood Hits	284	Target Neighborhood Hits	263	Shared Neighborhood Hits	75
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.062165 (rank : 103)
Query Neighborhood Hits	284	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.054820 (rank : 147)
Query Neighborhood Hits	284	Target Neighborhood Hits	986	Shared Neighborhood Hits	132
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFR15_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.054407 (rank : 150)
Query Neighborhood Hits	284	Target Neighborhood Hits	368	Shared Neighborhood Hits	78
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SRRM1_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.076658 (rank : 70)
Query Neighborhood Hits	284	Target Neighborhood Hits	690	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.078075 (rank : 66)
Query Neighborhood Hits	284	Target Neighborhood Hits	1296	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYN1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.060061 (rank : 121)
Query Neighborhood Hits	284	Target Neighborhood Hits	419	Shared Neighborhood Hits	111
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.052892 (rank : 162)
Query Neighborhood Hits	284	Target Neighborhood Hits	363	Shared Neighborhood Hits	101
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

T22D2_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.058678 (rank : 128)
Query Neighborhood Hits	284	Target Neighborhood Hits	250	Shared Neighborhood Hits	75
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TAF4_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.088284 (rank : 51)
Query Neighborhood Hits	284	Target Neighborhood Hits	687	Shared Neighborhood Hits	124
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TAU_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.061036 (rank : 113)
Query Neighborhood Hits	284	Target Neighborhood Hits	502	Shared Neighborhood Hits	72
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCOF_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.053121 (rank : 158)
Query Neighborhood Hits	284	Target Neighborhood Hits	471	Shared Neighborhood Hits	68
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

WASIP_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.087541 (rank : 52)
Query Neighborhood Hits	284	Target Neighborhood Hits	458	Shared Neighborhood Hits	121
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.084893 (rank : 56)
Query Neighborhood Hits	284	Target Neighborhood Hits	392	Shared Neighborhood Hits	115
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.050956 (rank : 175)
Query Neighborhood Hits	284	Target Neighborhood Hits	312	Shared Neighborhood Hits	94
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.054368 (rank : 151)
Query Neighborhood Hits	284	Target Neighborhood Hits	339	Shared Neighborhood Hits	94
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WBP11_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.067619 (rank : 92)
Query Neighborhood Hits	284	Target Neighborhood Hits	354	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.065604 (rank : 94)
Query Neighborhood Hits	284	Target Neighborhood Hits	362	Shared Neighborhood Hits	94
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WIRE_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.067528 (rank : 93)
Query Neighborhood Hits	284	Target Neighborhood Hits	329	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.064393 (rank : 96)
Query Neighborhood Hits	284	Target Neighborhood Hits	310	Shared Neighborhood Hits	90
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.055838 (rank : 145)
Query Neighborhood Hits	284	Target Neighborhood Hits	670	Shared Neighborhood Hits	101
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.061943 (rank : 107)
Query Neighborhood Hits	284	Target Neighborhood Hits	505	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZN207_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.060082 (rank : 120)
Query Neighborhood Hits	284	Target Neighborhood Hits	326	Shared Neighborhood Hits	62
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

HCN4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 8)
Query Neighborhood Hits	284	Target Neighborhood Hits	284	Shared Neighborhood Hits	284
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN4_HUMAN
NC score	0.983167 (rank : 2)	θ value	0 (rank : 7)
Query Neighborhood Hits	284	Target Neighborhood Hits	303	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN3_MOUSE
NC score	0.970977 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	284	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.970621 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	284	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN1_HUMAN
NC score	0.970029 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	284	Target Neighborhood Hits	120	Shared Neighborhood Hits	66
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN2_MOUSE
NC score	0.969965 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	284	Target Neighborhood Hits	278	Shared Neighborhood Hits	122
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN1_MOUSE
NC score	0.967669 (rank : 7)	θ value	0 (rank : 2)
Query Neighborhood Hits	284	Target Neighborhood Hits	172	Shared Neighborhood Hits	64
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_HUMAN
NC score	0.964523 (rank : 8)	θ value	0 (rank : 3)
Query Neighborhood Hits	284	Target Neighborhood Hits	369	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGA2_MOUSE
NC score	0.845351 (rank : 9)	θ value	8.59492e-43 (rank : 10)
Query Neighborhood Hits	284	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
NC score	0.839393 (rank : 10)	θ value	6.15952e-41 (rank : 12)
Query Neighborhood Hits	284	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
NC score	0.835294 (rank : 11)	θ value	1.46607e-42 (rank : 11)
Query Neighborhood Hits	284	Target Neighborhood Hits	149	Shared Neighborhood Hits	44
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.834307 (rank : 12)	θ value	1.01529e-43 (rank : 9)
Query Neighborhood Hits	284	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.833124 (rank : 13)	θ value	3.99248e-40 (rank : 13)
Query Neighborhood Hits	284	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB3_MOUSE
NC score	0.818549 (rank : 14)	θ value	1.79631e-32 (rank : 25)
Query Neighborhood Hits	284	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB1_HUMAN
NC score	0.815344 (rank : 15)	θ value	7.29293e-34 (rank : 22)
Query Neighborhood Hits	284	Target Neighborhood Hits	222	Shared Neighborhood Hits	65
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
NC score	0.804624 (rank : 16)	θ value	3.3877e-31 (rank : 27)
Query Neighborhood Hits	284	Target Neighborhood Hits	206	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH6_HUMAN
NC score	0.793216 (rank : 17)	θ value	1.98146e-39 (rank : 14)
Query Neighborhood Hits	284	Target Neighborhood Hits	222	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.790299 (rank : 18)	θ value	2.19075e-38 (rank : 17)
Query Neighborhood Hits	284	Target Neighborhood Hits	158	Shared Neighborhood Hits	56
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.790278 (rank : 19)	θ value	1.6774e-38 (rank : 15)
Query Neighborhood Hits	284	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
NC score	0.785793 (rank : 20)	θ value	1.6774e-38 (rank : 16)
Query Neighborhood Hits	284	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.781018 (rank : 21)	θ value	4.568e-36 (rank : 18)
Query Neighborhood Hits	284	Target Neighborhood Hits	107	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH4_HUMAN
NC score	0.777796 (rank : 22)	θ value	5.22648e-32 (rank : 26)
Query Neighborhood Hits	284	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH5_MOUSE
NC score	0.775823 (rank : 23)	θ value	1.32909e-35 (rank : 20)
Query Neighborhood Hits	284	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.775728 (rank : 24)	θ value	1.01765e-35 (rank : 19)
Query Neighborhood Hits	284	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH8_HUMAN
NC score	0.772171 (rank : 25)	θ value	1.9192e-34 (rank : 21)
Query Neighborhood Hits	284	Target Neighborhood Hits	104	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH1_MOUSE
NC score	0.770573 (rank : 26)	θ value	9.52487e-34 (rank : 24)
Query Neighborhood Hits	284	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.770212 (rank : 27)	θ value	9.52487e-34 (rank : 23)
Query Neighborhood Hits	284	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH3_HUMAN
NC score	0.764949 (rank : 28)	θ value	5.40856e-29 (rank : 28)
Query Neighborhood Hits	284	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
NC score	0.762826 (rank : 29)	θ value	5.40856e-29 (rank : 29)
Query Neighborhood Hits	284	Target Neighborhood Hits	133	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_HUMAN
NC score	0.324588 (rank : 30)	θ value	9.92553e-07 (rank : 30)
Query Neighborhood Hits	284	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
NC score	0.296572 (rank : 31)	θ value	1.29631e-06 (rank : 31)
Query Neighborhood Hits	284	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.287167 (rank : 32)	θ value	0.00134147 (rank : 47)
Query Neighborhood Hits	284	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.284271 (rank : 33)	θ value	0.00134147 (rank : 48)
Query Neighborhood Hits	284	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_MOUSE
NC score	0.272003 (rank : 34)	θ value	8.40245e-06 (rank : 35)
Query Neighborhood Hits	284	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.267930 (rank : 35)	θ value	1.43324e-05 (rank : 36)
Query Neighborhood Hits	284	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_MOUSE
NC score	0.261111 (rank : 36)	θ value	0.000461057 (rank : 45)
Query Neighborhood Hits	284	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
NC score	0.255653 (rank : 37)	θ value	0.00102713 (rank : 46)
Query Neighborhood Hits	284	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

CT152_MOUSE
NC score	0.164023 (rank : 38)	θ value	0.279714 (rank : 99)
Query Neighborhood Hits	284	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

PRP2_MOUSE
NC score	0.111763 (rank : 39)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	284	Target Neighborhood Hits	347	Shared Neighborhood Hits	100
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

NACAM_MOUSE
NC score	0.108550 (rank : 40)	θ value	0.00035302 (rank : 44)
Query Neighborhood Hits	284	Target Neighborhood Hits	1866	Shared Neighborhood Hits	160
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SRRM2_MOUSE
NC score	0.108484 (rank : 41)	θ value	0.000121331 (rank : 39)
Query Neighborhood Hits	284	Target Neighborhood Hits	1470	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PRP1_HUMAN
NC score	0.099711 (rank : 42)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	284	Target Neighborhood Hits	385	Shared Neighborhood Hits	102
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

NCOA6_HUMAN
NC score	0.098612 (rank : 43)	θ value	0.00665767 (rank : 54)
Query Neighborhood Hits	284	Target Neighborhood Hits	1202	Shared Neighborhood Hits	141
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CT152_HUMAN
NC score	0.097353 (rank : 44)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	284	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

GSCR1_HUMAN
NC score	0.094614 (rank : 45)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	284	Target Neighborhood Hits	674	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KCNKH_HUMAN
NC score	0.094168 (rank : 46)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	284	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

PRRT3_HUMAN
NC score	0.093790 (rank : 47)	θ value	0.0252991 (rank : 66)
Query Neighborhood Hits	284	Target Neighborhood Hits	998	Shared Neighborhood Hits	102
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BSN_MOUSE
NC score	0.091942 (rank : 48)	θ value	0.0252991 (rank : 63)
Query Neighborhood Hits	284	Target Neighborhood Hits	2057	Shared Neighborhood Hits	168
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BCL9_HUMAN
NC score	0.091891 (rank : 49)	θ value	0.0736092 (rank : 78)
Query Neighborhood Hits	284	Target Neighborhood Hits	1008	Shared Neighborhood Hits	104
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MBD6_HUMAN
NC score	0.089024 (rank : 50)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	284	Target Neighborhood Hits	349	Shared Neighborhood Hits	93
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

TAF4_HUMAN
NC score	0.088284 (rank : 51)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	284	Target Neighborhood Hits	687	Shared Neighborhood Hits	124
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WASIP_HUMAN
NC score	0.087541 (rank : 52)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	284	Target Neighborhood Hits	458	Shared Neighborhood Hits	121
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SRRM1_MOUSE
NC score	0.087405 (rank : 53)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	284	Target Neighborhood Hits	966	Shared Neighborhood Hits	128
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

RGS3_MOUSE
NC score	0.086040 (rank : 54)	θ value	5.44631e-05 (rank : 37)
Query Neighborhood Hits	284	Target Neighborhood Hits	1621	Shared Neighborhood Hits	136
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MUC7_HUMAN
NC score	0.085616 (rank : 55)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	284	Target Neighborhood Hits	538	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

WASIP_MOUSE
NC score	0.084893 (rank : 56)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	284	Target Neighborhood Hits	392	Shared Neighborhood Hits	115
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

KGP1B_MOUSE
NC score	0.084626 (rank : 57)	θ value	0.000121331 (rank : 38)
Query Neighborhood Hits	284	Target Neighborhood Hits	922	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.084597 (rank : 58)	θ value	0.00020696 (rank : 41)
Query Neighborhood Hits	284	Target Neighborhood Hits	921	Shared Neighborhood Hits	62
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.084291 (rank : 59)	θ value	0.00020696 (rank : 40)
Query Neighborhood Hits	284	Target Neighborhood Hits	901	Shared Neighborhood Hits	62
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP2_MOUSE
NC score	0.083956 (rank : 60)	θ value	1.69304e-06 (rank : 32)
Query Neighborhood Hits	284	Target Neighborhood Hits	1029	Shared Neighborhood Hits	58
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
NC score	0.083803 (rank : 61)	θ value	2.21117e-06 (rank : 33)
Query Neighborhood Hits	284	Target Neighborhood Hits	1023	Shared Neighborhood Hits	59
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

PRB3_HUMAN
NC score	0.083330 (rank : 62)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	284	Target Neighborhood Hits	318	Shared Neighborhood Hits	87
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

BCL9_MOUSE
NC score	0.083094 (rank : 63)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	284	Target Neighborhood Hits	770	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

OGFR_HUMAN
NC score	0.082456 (rank : 64)	θ value	0.365318 (rank : 110)
Query Neighborhood Hits	284	Target Neighborhood Hits	1582	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRB4S_HUMAN
NC score	0.081057 (rank : 65)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	284	Target Neighborhood Hits	330	Shared Neighborhood Hits	87
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SRRM2_HUMAN
NC score	0.078075 (rank : 66)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	284	Target Neighborhood Hits	1296	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MAGE1_HUMAN
NC score	0.077492 (rank : 67)	θ value	0.000270298 (rank : 43)
Query Neighborhood Hits	284	Target Neighborhood Hits	1389	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DOT1L_HUMAN
NC score	0.077443 (rank : 68)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	284	Target Neighborhood Hits	660	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

NCOA6_MOUSE
NC score	0.076886 (rank : 69)	θ value	0.813845 (rank : 133)
Query Neighborhood Hits	284	Target Neighborhood Hits	1076	Shared Neighborhood Hits	122
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SRRM1_HUMAN
NC score	0.076658 (rank : 70)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	284	Target Neighborhood Hits	690	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CN032_HUMAN
NC score	0.075783 (rank : 71)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	284	Target Neighborhood Hits	267	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CIC_HUMAN
NC score	0.074873 (rank : 72)	θ value	0.0736092 (rank : 79)
Query Neighborhood Hits	284	Target Neighborhood Hits	992	Shared Neighborhood Hits	145
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MUC1_HUMAN
NC score	0.074640 (rank : 73)	θ value	2.88788e-06 (rank : 34)
Query Neighborhood Hits	284	Target Neighborhood Hits	975	Shared Neighborhood Hits	96
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SC24C_HUMAN
NC score	0.074014 (rank : 74)	θ value	1.06291 (rank : 146)
Query Neighborhood Hits	284	Target Neighborhood Hits	662	Shared Neighborhood Hits	93
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MLL3_HUMAN
NC score	0.073746 (rank : 75)	θ value	0.00509761 (rank : 52)
Query Neighborhood Hits	284	Target Neighborhood Hits	1644	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ATN1_HUMAN
NC score	0.073717 (rank : 76)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	284	Target Neighborhood Hits	676	Shared Neighborhood Hits	128
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAT3_MOUSE
NC score	0.073342 (rank : 77)	θ value	0.813845 (rank : 129)
Query Neighborhood Hits	284	Target Neighborhood Hits	518	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CN032_MOUSE
NC score	0.072794 (rank : 78)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	284	Target Neighborhood Hits	233	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CBP_HUMAN
NC score	0.072365 (rank : 79)	θ value	0.0193708 (rank : 59)
Query Neighborhood Hits	284	Target Neighborhood Hits	941	Shared Neighborhood Hits	122
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BSN_HUMAN
NC score	0.072091 (rank : 80)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	284	Target Neighborhood Hits	1537	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PI5PA_HUMAN
NC score	0.071815 (rank : 81)	θ value	0.0563607 (rank : 77)
Query Neighborhood Hits	284	Target Neighborhood Hits	749	Shared Neighborhood Hits	113
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ZN750_MOUSE
NC score	0.071369 (rank : 82)	θ value	0.00509761 (rank : 53)
Query Neighborhood Hits	284	Target Neighborhood Hits	346	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

MLL2_HUMAN
NC score	0.070720 (rank : 83)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	284	Target Neighborhood Hits	1788	Shared Neighborhood Hits	163
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BAT2_HUMAN
NC score	0.070166 (rank : 84)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	284	Target Neighborhood Hits	931	Shared Neighborhood Hits	131
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PRG4_HUMAN
NC score	0.070043 (rank : 85)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	284	Target Neighborhood Hits	764	Shared Neighborhood Hits	113
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PCLO_MOUSE
NC score	0.069109 (rank : 86)	θ value	0.62314 (rank : 123)
Query Neighborhood Hits	284	Target Neighborhood Hits	2275	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRR12_HUMAN
NC score	0.068746 (rank : 87)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	284	Target Neighborhood Hits	460	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SAPS1_HUMAN
NC score	0.068735 (rank : 88)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	284	Target Neighborhood Hits	704	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MISS_MOUSE
NC score	0.068221 (rank : 89)	θ value	0.813845 (rank : 132)
Query Neighborhood Hits	284	Target Neighborhood Hits	444	Shared Neighborhood Hits	71
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

R3HD2_MOUSE
NC score	0.068165 (rank : 90)	θ value	0.21417 (rank : 97)
Query Neighborhood Hits	284	Target Neighborhood Hits	397	Shared Neighborhood Hits	60
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

MUCDL_HUMAN
NC score	0.068097 (rank : 91)	θ value	0.125558 (rank : 86)
Query Neighborhood Hits	284	Target Neighborhood Hits	777	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

WBP11_HUMAN
NC score	0.067619 (rank : 92)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	284	Target Neighborhood Hits	354	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WIRE_HUMAN
NC score	0.067528 (rank : 93)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	284	Target Neighborhood Hits	329	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WBP11_MOUSE
NC score	0.065604 (rank : 94)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	284	Target Neighborhood Hits	362	Shared Neighborhood Hits	94
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

RPGF4_MOUSE
NC score	0.064503 (rank : 95)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	284	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

WIRE_MOUSE
NC score	0.064393 (rank : 96)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	284	Target Neighborhood Hits	310	Shared Neighborhood Hits	90
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CBP_MOUSE
NC score	0.064155 (rank : 97)	θ value	1.06291 (rank : 142)
Query Neighborhood Hits	284	Target Neighborhood Hits	1051	Shared Neighborhood Hits	122
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SF3A2_HUMAN
NC score	0.063965 (rank : 98)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	284	Target Neighborhood Hits	263	Shared Neighborhood Hits	75
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

MARCS_HUMAN
NC score	0.063543 (rank : 99)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	284	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

FA8A1_HUMAN
NC score	0.062870 (rank : 100)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	284	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

KCNKF_HUMAN
NC score	0.062801 (rank : 101)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	284	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

CRSP2_HUMAN
NC score	0.062749 (rank : 102)	θ value	0.21417 (rank : 95)
Query Neighborhood Hits	284	Target Neighborhood Hits	380	Shared Neighborhood Hits	64
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

SF3A2_MOUSE
NC score	0.062165 (rank : 103)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	284	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

RPGF4_HUMAN
NC score	0.062152 (rank : 104)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	284	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

GGN_MOUSE
NC score	0.062126 (rank : 105)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	284	Target Neighborhood Hits	311	Shared Neighborhood Hits	84
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

ALEX_HUMAN
NC score	0.062116 (rank : 106)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	284	Target Neighborhood Hits	361	Shared Neighborhood Hits	82
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

YLPM1_MOUSE
NC score	0.061943 (rank : 107)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	284	Target Neighborhood Hits	505	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

NCOR2_MOUSE
NC score	0.061802 (rank : 108)	θ value	0.0563607 (rank : 76)
Query Neighborhood Hits	284	Target Neighborhood Hits	790	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

RGS3_HUMAN
NC score	0.061755 (rank : 109)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	284	Target Neighborhood Hits	1375	Shared Neighborhood Hits	95
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GGN_HUMAN
NC score	0.061659 (rank : 110)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	284	Target Neighborhood Hits	269	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

EP300_HUMAN
NC score	0.061630 (rank : 111)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	284	Target Neighborhood Hits	821	Shared Neighborhood Hits	120
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

KCNK2_HUMAN
NC score	0.061264 (rank : 112)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	284	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

TAU_MOUSE
NC score	0.061036 (rank : 113)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	284	Target Neighborhood Hits	502	Shared Neighborhood Hits	72
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

NCOR2_HUMAN
NC score	0.060934 (rank : 114)	θ value	1.81305 (rank : 163)
Query Neighborhood Hits	284	Target Neighborhood Hits	870	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

KCNK2_MOUSE
NC score	0.060834 (rank : 115)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	284	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

RAPH1_HUMAN
NC score	0.060647 (rank : 116)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	284	Target Neighborhood Hits	593	Shared Neighborhood Hits	118
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

BAT3_HUMAN
NC score	0.060330 (rank : 117)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	284	Target Neighborhood Hits	490	Shared Neighborhood Hits	71
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CJ078_MOUSE
NC score	0.060133 (rank : 118)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	284	Target Neighborhood Hits	559	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MLL3_MOUSE
NC score	0.060085 (rank : 119)	θ value	0.365318 (rank : 109)
Query Neighborhood Hits	284	Target Neighborhood Hits	1399	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ZN207_HUMAN
NC score	0.060082 (rank : 120)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	284	Target Neighborhood Hits	326	Shared Neighborhood Hits	62
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

SYN1_HUMAN
NC score	0.060061 (rank : 121)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	284	Target Neighborhood Hits	419	Shared Neighborhood Hits	111
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

KCNK6_HUMAN
NC score	0.059824 (rank : 122)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	284	Target Neighborhood Hits	79	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

PCLO_HUMAN
NC score	0.059720 (rank : 123)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	284	Target Neighborhood Hits	2046	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ENAH_MOUSE
NC score	0.059455 (rank : 124)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	284	Target Neighborhood Hits	919	Shared Neighborhood Hits	130
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MDC1_MOUSE
NC score	0.059441 (rank : 125)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	284	Target Neighborhood Hits	998	Shared Neighborhood Hits	92
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

GRIN1_HUMAN
NC score	0.058956 (rank : 126)	θ value	0.0431538 (rank : 71)
Query Neighborhood Hits	284	Target Neighborhood Hits	681	Shared Neighborhood Hits	77
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

KCNK3_HUMAN
NC score	0.058695 (rank : 127)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	284	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

T22D2_HUMAN
NC score	0.058678 (rank : 128)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	284	Target Neighborhood Hits	250	Shared Neighborhood Hits	75
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

EPN3_HUMAN
NC score	0.058625 (rank : 129)	θ value	0.00869519 (rank : 55)
Query Neighborhood Hits	284	Target Neighborhood Hits	197	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

PRP5_HUMAN
NC score	0.058571 (rank : 130)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	284	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

DIDO1_HUMAN
NC score	0.058424 (rank : 131)	θ value	0.0736092 (rank : 80)
Query Neighborhood Hits	284	Target Neighborhood Hits	960	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MUC1_MOUSE
NC score	0.058247 (rank : 132)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	284	Target Neighborhood Hits	388	Shared Neighborhood Hits	57
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

BAT2_MOUSE
NC score	0.058076 (rank : 133)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	284	Target Neighborhood Hits	947	Shared Neighborhood Hits	124
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RERE_MOUSE
NC score	0.057812 (rank : 134)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	284	Target Neighborhood Hits	785	Shared Neighborhood Hits	130
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RERE_HUMAN
NC score	0.057515 (rank : 135)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	284	Target Neighborhood Hits	779	Shared Neighborhood Hits	116
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

KCNK3_MOUSE
NC score	0.057157 (rank : 136)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	284	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

TCGAP_HUMAN
NC score	0.056776 (rank : 137)	θ value	0.00020696 (rank : 42)
Query Neighborhood Hits	284	Target Neighborhood Hits	872	Shared Neighborhood Hits	87
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GRIN1_MOUSE
NC score	0.056770 (rank : 138)	θ value	1.06291 (rank : 144)
Query Neighborhood Hits	284	Target Neighborhood Hits	337	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SF3B1_HUMAN
NC score	0.056478 (rank : 139)	θ value	0.0961366 (rank : 81)
Query Neighborhood Hits	284	Target Neighborhood Hits	341	Shared Neighborhood Hits	43
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.056444 (rank : 140)	θ value	0.0961366 (rank : 82)
Query Neighborhood Hits	284	Target Neighborhood Hits	352	Shared Neighborhood Hits	44
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CIC_MOUSE
NC score	0.056418 (rank : 141)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	284	Target Neighborhood Hits	742	Shared Neighborhood Hits	126
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CS016_HUMAN
NC score	0.056321 (rank : 142)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	284	Target Neighborhood Hits	310	Shared Neighborhood Hits	71
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

KCNKA_HUMAN
NC score	0.056320 (rank : 143)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	284	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

MILK1_MOUSE
NC score	0.056212 (rank : 144)	θ value	0.365318 (rank : 108)
Query Neighborhood Hits	284	Target Neighborhood Hits	788	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

YLPM1_HUMAN
NC score	0.055838 (rank : 145)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	284	Target Neighborhood Hits	670	Shared Neighborhood Hits	101
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

BASP_HUMAN
NC score	0.055321 (rank : 146)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	284	Target Neighborhood Hits	321	Shared Neighborhood Hits	56
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SFPQ_HUMAN
NC score	0.054820 (rank : 147)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	284	Target Neighborhood Hits	986	Shared Neighborhood Hits	132
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

KCNK4_HUMAN
NC score	0.054740 (rank : 148)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	284	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

CPSF6_MOUSE
NC score	0.054567 (rank : 149)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	284	Target Neighborhood Hits	356	Shared Neighborhood Hits	85
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

SFR15_HUMAN
NC score	0.054407 (rank : 150)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	284	Target Neighborhood Hits	368	Shared Neighborhood Hits	78
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

WASL_MOUSE
NC score	0.054368 (rank : 151)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	284	Target Neighborhood Hits	339	Shared Neighborhood Hits	94
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MAML1_MOUSE
NC score	0.054067 (rank : 152)	θ value	0.0113563 (rank : 58)
Query Neighborhood Hits	284	Target Neighborhood Hits	279	Shared Neighborhood Hits	44
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

CPSF6_HUMAN
NC score	0.053579 (rank : 153)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	284	Target Neighborhood Hits	359	Shared Neighborhood Hits	85
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

TGON2_HUMAN
NC score	0.053400 (rank : 154)	θ value	0.0961366 (rank : 83)
Query Neighborhood Hits	284	Target Neighborhood Hits	1037	Shared Neighborhood Hits	83
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SSBP4_HUMAN
NC score	0.053377 (rank : 155)	θ value	0.813845 (rank : 135)
Query Neighborhood Hits	284	Target Neighborhood Hits	753	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

NFH_MOUSE
NC score	0.053192 (rank : 156)	θ value	0.0431538 (rank : 72)
Query Neighborhood Hits	284	Target Neighborhood Hits	2247	Shared Neighborhood Hits	138
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BASP_MOUSE
NC score	0.053149 (rank : 157)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	284	Target Neighborhood Hits	260	Shared Neighborhood Hits	41
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TCOF_MOUSE
NC score	0.053121 (rank : 158)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	284	Target Neighborhood Hits	471	Shared Neighborhood Hits	68
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

CIZ1_HUMAN
NC score	0.052979 (rank : 159)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	284	Target Neighborhood Hits	359	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CGRE1_HUMAN
NC score	0.052950 (rank : 160)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	284	Target Neighborhood Hits	354	Shared Neighborhood Hits	32
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

TARSH_HUMAN
NC score	0.052908 (rank : 161)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	284	Target Neighborhood Hits	768	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SYN1_MOUSE
NC score	0.052892 (rank : 162)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	284	Target Neighborhood Hits	363	Shared Neighborhood Hits	101
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CABIN_HUMAN
NC score	0.052628 (rank : 163)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	284	Target Neighborhood Hits	490	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

MAML3_HUMAN
NC score	0.052573 (rank : 164)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	284	Target Neighborhood Hits	323	Shared Neighborhood Hits	45
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

SON_HUMAN
NC score	0.052220 (rank : 165)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	284	Target Neighborhood Hits	1568	Shared Neighborhood Hits	120
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PDZD2_HUMAN
NC score	0.052077 (rank : 166)	θ value	0.62314 (rank : 124)
Query Neighborhood Hits	284	Target Neighborhood Hits	772	Shared Neighborhood Hits	68
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RPGF3_MOUSE
NC score	0.052071 (rank : 167)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	284	Target Neighborhood Hits	54	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

PRPC_HUMAN
NC score	0.052053 (rank : 168)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	284	Target Neighborhood Hits	165	Shared Neighborhood Hits	51
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

MKL1_MOUSE
NC score	0.051992 (rank : 169)	θ value	0.21417 (rank : 96)
Query Neighborhood Hits	284	Target Neighborhood Hits	667	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CRTC1_HUMAN
NC score	0.051523 (rank : 170)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	284	Target Neighborhood Hits	319	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

HRBL_MOUSE
NC score	0.051439 (rank : 171)	θ value	0.0113563 (rank : 57)
Query Neighborhood Hits	284	Target Neighborhood Hits	269	Shared Neighborhood Hits	34
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

T22D4_HUMAN
NC score	0.051339 (rank : 172)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	284	Target Neighborhood Hits	403	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

MDC1_HUMAN
NC score	0.051074 (rank : 173)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	284	Target Neighborhood Hits	1446	Shared Neighborhood Hits	107
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

S23IP_MOUSE
NC score	0.050995 (rank : 174)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	284	Target Neighborhood Hits	363	Shared Neighborhood Hits	56
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

WASL_HUMAN
NC score	0.050956 (rank : 175)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	284	Target Neighborhood Hits	312	Shared Neighborhood Hits	94
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

TAU_HUMAN
NC score	0.050652 (rank : 176)	θ value	1.06291 (rank : 147)
Query Neighborhood Hits	284	Target Neighborhood Hits	448	Shared Neighborhood Hits	74
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PHLB1_MOUSE
NC score	0.050488 (rank : 177)	θ value	0.0193708 (rank : 61)
Query Neighborhood Hits	284	Target Neighborhood Hits	678	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

EPN3_MOUSE
NC score	0.050279 (rank : 178)	θ value	0.365318 (rank : 106)
Query Neighborhood Hits	284	Target Neighborhood Hits	312	Shared Neighborhood Hits	53
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

PO121_HUMAN
NC score	0.050229 (rank : 179)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	284	Target Neighborhood Hits	344	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CS007_MOUSE
NC score	0.050170 (rank : 180)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	284	Target Neighborhood Hits	464	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

PI5PA_MOUSE
NC score	0.050031 (rank : 181)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	284	Target Neighborhood Hits	331	Shared Neighborhood Hits	78
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

KCNKG_HUMAN
NC score	0.050013 (rank : 182)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	284	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

NCOA2_HUMAN
NC score	0.049703 (rank : 183)	θ value	0.0193708 (rank : 60)
Query Neighborhood Hits	284	Target Neighborhood Hits	281	Shared Neighborhood Hits	35
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

JPH2_HUMAN
NC score	0.049674 (rank : 184)	θ value	0.0563607 (rank : 74)
Query Neighborhood Hits	284	Target Neighborhood Hits	639	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CBL_MOUSE
NC score	0.049258 (rank : 185)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	284	Target Neighborhood Hits	426	Shared Neighborhood Hits	37
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TARA_HUMAN
NC score	0.048743 (rank : 186)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	284	Target Neighborhood Hits	1626	Shared Neighborhood Hits	110
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DCNP1_HUMAN
NC score	0.048527 (rank : 187)	θ value	0.365318 (rank : 105)
Query Neighborhood Hits	284	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF63	Gene names	DCNP1, C5orf20
Domain Architecture	No domain graphic available
Description	Dendritic cell nuclear protein 1.

CT174_HUMAN
NC score	0.048238 (rank : 188)	θ value	1.38821 (rank : 150)
Query Neighborhood Hits	284	Target Neighborhood Hits	181	Shared Neighborhood Hits	35
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

HAIR_HUMAN
NC score	0.048052 (rank : 189)	θ value	0.0252991 (rank : 64)
Query Neighborhood Hits	284	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

PHLB1_HUMAN
NC score	0.047851 (rank : 190)	θ value	0.00869519 (rank : 56)
Query Neighborhood Hits	284	Target Neighborhood Hits	1038	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MAVS_HUMAN
NC score	0.047822 (rank : 191)	θ value	4.03905 (rank : 218)
Query Neighborhood Hits	284	Target Neighborhood Hits	271	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

CEP68_HUMAN
NC score	0.047411 (rank : 192)	θ value	0.21417 (rank : 94)
Query Neighborhood Hits	284	Target Neighborhood Hits	128	Shared Neighborhood Hits	27
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CECR2_HUMAN
NC score	0.047398 (rank : 193)	θ value	0.125558 (rank : 84)
Query Neighborhood Hits	284	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

MEF2D_HUMAN
NC score	0.046993 (rank : 194)	θ value	0.365318 (rank : 107)
Query Neighborhood Hits	284	Target Neighborhood Hits	170	Shared Neighborhood Hits	39
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

TPO_MOUSE
NC score	0.046613 (rank : 195)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	284	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

MEF2D_MOUSE
NC score	0.046328 (rank : 196)	θ value	0.47712 (rank : 113)
Query Neighborhood Hits	284	Target Neighborhood Hits	146	Shared Neighborhood Hits	42
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MINT_MOUSE
NC score	0.045854 (rank : 197)	θ value	1.81305 (rank : 162)
Query Neighborhood Hits	284	Target Neighborhood Hits	1514	Shared Neighborhood Hits	98
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CI079_HUMAN
NC score	0.044983 (rank : 198)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	284	Target Neighborhood Hits	288	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

SC24A_MOUSE
NC score	0.043909 (rank : 199)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	284	Target Neighborhood Hits	394	Shared Neighborhood Hits	63
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

CBL_HUMAN
NC score	0.043883 (rank : 200)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	284	Target Neighborhood Hits	353	Shared Neighborhood Hits	28
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

PER3_HUMAN
NC score	0.042137 (rank : 201)	θ value	0.0431538 (rank : 73)
Query Neighborhood Hits	284	Target Neighborhood Hits	479	Shared Neighborhood Hits	68
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

NRX2B_HUMAN
NC score	0.042015 (rank : 202)	θ value	1.81305 (rank : 165)
Query Neighborhood Hits	284	Target Neighborhood Hits	481	Shared Neighborhood Hits	48
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

ZIMP7_MOUSE
NC score	0.040356 (rank : 203)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	284	Target Neighborhood Hits	566	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

KCNK1_MOUSE
NC score	0.039210 (rank : 204)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	284	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

ATX7_HUMAN
NC score	0.038972 (rank : 205)	θ value	0.21417 (rank : 93)
Query Neighborhood Hits	284	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

PK1L1_HUMAN
NC score	0.038400 (rank : 206)	θ value	0.0252991 (rank : 65)
Query Neighborhood Hits	284	Target Neighborhood Hits	140	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

RUSC2_MOUSE
NC score	0.038230 (rank : 207)	θ value	0.62314 (rank : 126)
Query Neighborhood Hits	284	Target Neighborhood Hits	305	Shared Neighborhood Hits	55
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CAC1G_HUMAN
NC score	0.038139 (rank : 208)	θ value	0.365318 (rank : 104)
Query Neighborhood Hits	284	Target Neighborhood Hits	587	Shared Neighborhood Hits	61
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

IF4G1_MOUSE
NC score	0.037976 (rank : 209)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	284	Target Neighborhood Hits	534	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PP14A_MOUSE
NC score	0.037222 (rank : 210)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	284	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VC7, Q99MB9	Gene names	Ppp1r14a, Cpi17
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (CPI-17).

CSKI1_HUMAN
NC score	0.036583 (rank : 211)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	284	Target Neighborhood Hits	997	Shared Neighborhood Hits	125
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NCOA2_MOUSE
NC score	0.036159 (rank : 212)	θ value	0.0563607 (rank : 75)
Query Neighborhood Hits	284	Target Neighborhood Hits	281	Shared Neighborhood Hits	40
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

MAGD4_HUMAN
NC score	0.035396 (rank : 213)	θ value	0.47712 (rank : 112)
Query Neighborhood Hits	284	Target Neighborhood Hits	338	Shared Neighborhood Hits	52
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MEF2B_MOUSE
NC score	0.034654 (rank : 214)	θ value	0.813845 (rank : 131)
Query Neighborhood Hits	284	Target Neighborhood Hits	218	Shared Neighborhood Hits	28
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MAML2_HUMAN
NC score	0.034650 (rank : 215)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	284	Target Neighborhood Hits	360	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

CO5A2_HUMAN
NC score	0.034447 (rank : 216)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	284	Target Neighborhood Hits	760	Shared Neighborhood Hits	92
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

IRS2_MOUSE
NC score	0.034288 (rank : 217)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	284	Target Neighborhood Hits	248	Shared Neighborhood Hits	66
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

CSKI1_MOUSE
NC score	0.034206 (rank : 218)	θ value	0.62314 (rank : 118)
Query Neighborhood Hits	284	Target Neighborhood Hits	1031	Shared Neighborhood Hits	119
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYCD_MOUSE
NC score	0.033915 (rank : 219)	θ value	0.125558 (rank : 87)
Query Neighborhood Hits	284	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

GNAS1_HUMAN
NC score	0.033673 (rank : 220)	θ value	0.125558 (rank : 85)
Query Neighborhood Hits	284	Target Neighborhood Hits	278	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GNAS1_MOUSE
NC score	0.033603 (rank : 221)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	284	Target Neighborhood Hits	651	Shared Neighborhood Hits	85
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

RUNX3_MOUSE
NC score	0.033577 (rank : 222)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	284	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX3_HUMAN
NC score	0.033233 (rank : 223)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	284	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

HTRA4_HUMAN
NC score	0.033214 (rank : 224)	θ value	2.36792 (rank : 177)
Query Neighborhood Hits	284	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

CEL_HUMAN
NC score	0.032704 (rank : 225)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	284	Target Neighborhood Hits	896	Shared Neighborhood Hits	90
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FYB_HUMAN
NC score	0.031940 (rank : 226)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	284	Target Neighborhood Hits	379	Shared Neighborhood Hits	50
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

BPTF_HUMAN
NC score	0.029699 (rank : 227)	θ value	1.06291 (rank : 141)
Query Neighborhood Hits	284	Target Neighborhood Hits	786	Shared Neighborhood Hits	62
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MAST4_HUMAN
NC score	0.029246 (rank : 228)	θ value	0.00228821 (rank : 50)
Query Neighborhood Hits	284	Target Neighborhood Hits	1804	Shared Neighborhood Hits	118
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

HCFC1_HUMAN
NC score	0.029179 (rank : 229)	θ value	2.36792 (rank : 176)
Query Neighborhood Hits	284	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

NU133_HUMAN
NC score	0.029171 (rank : 230)	θ value	0.279714 (rank : 102)
Query Neighborhood Hits	284	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

HCFC1_MOUSE
NC score	0.029015 (rank : 231)	θ value	4.03905 (rank : 216)
Query Neighborhood Hits	284	Target Neighborhood Hits	348	Shared Neighborhood Hits	37
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

JIP1_HUMAN
NC score	0.028983 (rank : 232)	θ value	0.62314 (rank : 120)
Query Neighborhood Hits	284	Target Neighborhood Hits	271	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

RUNX1_HUMAN
NC score	0.028502 (rank : 233)	θ value	0.21417 (rank : 98)
Query Neighborhood Hits	284	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

AFF2_MOUSE
NC score	0.028154 (rank : 234)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	284	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

NRX2A_HUMAN
NC score	0.027442 (rank : 235)	θ value	1.81305 (rank : 164)
Query Neighborhood Hits	284	Target Neighborhood Hits	614	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

ZIMP7_HUMAN
NC score	0.026989 (rank : 236)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	284	Target Neighborhood Hits	290	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

PHLPP_HUMAN
NC score	0.026640 (rank : 237)	θ value	1.81305 (rank : 167)
Query Neighborhood Hits	284	Target Neighborhood Hits	604	Shared Neighborhood Hits	57
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

S5A2_HUMAN
NC score	0.026444 (rank : 238)	θ value	1.81305 (rank : 168)
Query Neighborhood Hits	284	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P31213, Q9BYE6	Gene names	SRD5A2
Domain Architecture
Description	3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5) (Steroid 5- alpha-reductase 2) (SR type 2) (5 alpha-SR2) (Type II 5-alpha reductase).

EHMT2_MOUSE
NC score	0.026140 (rank : 239)	θ value	0.00390308 (rank : 51)
Query Neighborhood Hits	284	Target Neighborhood Hits	750	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

RP3A_MOUSE
NC score	0.026089 (rank : 240)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	284	Target Neighborhood Hits	510	Shared Neighborhood Hits	67
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RUNX1_MOUSE
NC score	0.026035 (rank : 241)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	284	Target Neighborhood Hits	93	Shared Neighborhood Hits	20
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

MAGC1_HUMAN
NC score	0.025712 (rank : 242)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	284	Target Neighborhood Hits	431	Shared Neighborhood Hits	72
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

CAC1H_HUMAN
NC score	0.025642 (rank : 243)	θ value	0.62314 (rank : 116)
Query Neighborhood Hits	284	Target Neighborhood Hits	307	Shared Neighborhood Hits	43
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

K0056_HUMAN
NC score	0.025526 (rank : 244)	θ value	1.06291 (rank : 145)
Query Neighborhood Hits	284	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

DMRTD_HUMAN
NC score	0.025264 (rank : 245)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	284	Target Neighborhood Hits	216	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

AMPH_HUMAN
NC score	0.024423 (rank : 246)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	284	Target Neighborhood Hits	455	Shared Neighborhood Hits	43
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ACINU_MOUSE
NC score	0.024356 (rank : 247)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	284	Target Neighborhood Hits	712	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

YETS2_MOUSE
NC score	0.023604 (rank : 248)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	284	Target Neighborhood Hits	278	Shared Neighborhood Hits	45
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

KCD18_HUMAN
NC score	0.023312 (rank : 249)	θ value	0.279714 (rank : 101)
Query Neighborhood Hits	284	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

IQEC3_MOUSE
NC score	0.023101 (rank : 250)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	284	Target Neighborhood Hits	274	Shared Neighborhood Hits	45
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

SPEG_MOUSE
NC score	0.022953 (rank : 251)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	284	Target Neighborhood Hits	1959	Shared Neighborhood Hits	134
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

F100B_MOUSE
NC score	0.022408 (rank : 252)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	284	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

CSPG5_MOUSE
NC score	0.022384 (rank : 253)	θ value	1.38821 (rank : 149)
Query Neighborhood Hits	284	Target Neighborhood Hits	211	Shared Neighborhood Hits	16
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CO7A1_HUMAN
NC score	0.021889 (rank : 254)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	284	Target Neighborhood Hits	807	Shared Neighborhood Hits	82
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CD248_MOUSE
NC score	0.021610 (rank : 255)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	284	Target Neighborhood Hits	578	Shared Neighborhood Hits	47
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

AL2S4_MOUSE
NC score	0.021476 (rank : 256)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	284	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

GMEB2_HUMAN
NC score	0.021438 (rank : 257)	θ value	0.813845 (rank : 130)
Query Neighborhood Hits	284	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GPS2_HUMAN
NC score	0.021032 (rank : 258)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	284	Target Neighborhood Hits	459	Shared Neighborhood Hits	24
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

DOCK4_MOUSE
NC score	0.020904 (rank : 259)	θ value	0.47712 (rank : 111)
Query Neighborhood Hits	284	Target Neighborhood Hits	210	Shared Neighborhood Hits	32
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

B4GT1_HUMAN
NC score	0.020739 (rank : 260)	θ value	1.06291 (rank : 140)
Query Neighborhood Hits	284	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

PGCA_MOUSE
NC score	0.020726 (rank : 261)	θ value	1.81305 (rank : 166)
Query Neighborhood Hits	284	Target Neighborhood Hits	643	Shared Neighborhood Hits	48
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

XKR7_MOUSE
NC score	0.020647 (rank : 262)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	284	Target Neighborhood Hits	146	Shared Neighborhood Hits	14
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

SEM6C_MOUSE
NC score	0.019527 (rank : 263)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	284	Target Neighborhood Hits	352	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

DOCK4_HUMAN
NC score	0.019492 (rank : 264)	θ value	1.38821 (rank : 151)
Query Neighborhood Hits	284	Target Neighborhood Hits	237	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

GAK12_HUMAN
NC score	0.019026 (rank : 265)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	284	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SQSTM_HUMAN
NC score	0.018801 (rank : 266)	θ value	1.38821 (rank : 153)
Query Neighborhood Hits	284	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).

GAK4_HUMAN
NC score	0.018789 (rank : 267)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	284	Target Neighborhood Hits	415	Shared Neighborhood Hits	39
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.018678 (rank : 268)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	284	Target Neighborhood Hits	409	Shared Neighborhood Hits	38
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
NC score	0.018475 (rank : 269)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	284	Target Neighborhood Hits	429	Shared Neighborhood Hits	37
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CAC1B_MOUSE
NC score	0.018406 (rank : 270)	θ value	0.62314 (rank : 115)
Query Neighborhood Hits	284	Target Neighborhood Hits	351	Shared Neighborhood Hits	47
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

GAK6_HUMAN
NC score	0.018241 (rank : 271)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	284	Target Neighborhood Hits	392	Shared Neighborhood Hits	38
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CAC1H_MOUSE
NC score	0.018068 (rank : 272)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	284	Target Neighborhood Hits	230	Shared Neighborhood Hits	31
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

ZN687_HUMAN
NC score	0.017930 (rank : 273)	θ value	1.38821 (rank : 157)
Query Neighborhood Hits	284	Target Neighborhood Hits	1244	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AFF2_HUMAN
NC score	0.017919 (rank : 274)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	284	Target Neighborhood Hits	218	Shared Neighborhood Hits	24
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

INVS_MOUSE
NC score	0.017908 (rank : 275)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	284	Target Neighborhood Hits	609	Shared Neighborhood Hits	51
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

CU058_HUMAN
NC score	0.017756 (rank : 276)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	284	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P58505	Gene names	C21orf58
Domain Architecture	No domain graphic available
Description	Protein C21orf58.

PYR1_HUMAN
NC score	0.017640 (rank : 277)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	284	Target Neighborhood Hits	119	Shared Neighborhood Hits	17
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

SOX13_MOUSE
NC score	0.017636 (rank : 278)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	284	Target Neighborhood Hits	495	Shared Neighborhood Hits	34
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

GAK2_HUMAN
NC score	0.017368 (rank : 279)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	284	Target Neighborhood Hits	406	Shared Neighborhood Hits	36
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RFIP5_MOUSE
NC score	0.017228 (rank : 280)	θ value	1.38821 (rank : 152)
Query Neighborhood Hits	284	Target Neighborhood Hits	126	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

ZN516_MOUSE
NC score	0.016974 (rank : 281)	θ value	0.0193708 (rank : 62)
Query Neighborhood Hits	284	Target Neighborhood Hits	1197	Shared Neighborhood Hits	77
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

SC6A5_MOUSE
NC score	0.016483 (rank : 282)	θ value	0.125558 (rank : 88)
Query Neighborhood Hits	284	Target Neighborhood Hits	135	Shared Neighborhood Hits	20
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

ULK1_MOUSE
NC score	0.016338 (rank : 283)	θ value	0.813845 (rank : 138)
Query Neighborhood Hits	284	Target Neighborhood Hits	1214	Shared Neighborhood Hits	73
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ULK1_HUMAN
NC score	0.016333 (rank : 284)	θ value	0.163984 (rank : 92)
Query Neighborhood Hits	284	Target Neighborhood Hits	1121	Shared Neighborhood Hits	68
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

SNPC4_MOUSE
NC score	0.016017 (rank : 285)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	284	Target Neighborhood Hits	237	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

ARNT_MOUSE
NC score	0.015945 (rank : 286)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	284	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

FOG1_MOUSE
NC score	0.015923 (rank : 287)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	284	Target Neighborhood Hits	1237	Shared Neighborhood Hits	91
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GAB2_MOUSE
NC score	0.015791 (rank : 288)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	284	Target Neighborhood Hits	220	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

RPGF1_HUMAN
NC score	0.015561 (rank : 289)	θ value	0.62314 (rank : 125)
Query Neighborhood Hits	284	Target Neighborhood Hits	262	Shared Neighborhood Hits	14
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

CAMKV_HUMAN
NC score	0.015550 (rank : 290)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	284	Target Neighborhood Hits	1084	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CP007_MOUSE
NC score	0.015320 (rank : 291)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	284	Target Neighborhood Hits	231	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

TLE1_MOUSE
NC score	0.015202 (rank : 292)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	284	Target Neighborhood Hits	491	Shared Neighborhood Hits	30
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

PAK4_MOUSE
NC score	0.015133 (rank : 293)	θ value	0.0330416 (rank : 68)
Query Neighborhood Hits	284	Target Neighborhood Hits	1098	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

MARK2_HUMAN
NC score	0.015119 (rank : 294)	θ value	0.163984 (rank : 89)
Query Neighborhood Hits	284	Target Neighborhood Hits	1056	Shared Neighborhood Hits	51
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

DCC_MOUSE
NC score	0.014971 (rank : 295)	θ value	0.62314 (rank : 119)
Query Neighborhood Hits	284	Target Neighborhood Hits	896	Shared Neighborhood Hits	44
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

US6NL_HUMAN
NC score	0.014955 (rank : 296)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	284	Target Neighborhood Hits	201	Shared Neighborhood Hits	24
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

TLE1_HUMAN
NC score	0.014913 (rank : 297)	θ value	0.813845 (rank : 136)
Query Neighborhood Hits	284	Target Neighborhood Hits	485	Shared Neighborhood Hits	27
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

ASPX_HUMAN
NC score	0.014095 (rank : 298)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	284	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

PKN3_MOUSE
NC score	0.013976 (rank : 299)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	284	Target Neighborhood Hits	1009	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

FILA_HUMAN
NC score	0.013889 (rank : 300)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	284	Target Neighborhood Hits	685	Shared Neighborhood Hits	38
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

AATK_HUMAN
NC score	0.013492 (rank : 301)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	284	Target Neighborhood Hits	1243	Shared Neighborhood Hits	89
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

TRIM8_HUMAN
NC score	0.013275 (rank : 302)	θ value	0.813845 (rank : 137)
Query Neighborhood Hits	284	Target Neighborhood Hits	650	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

STK10_MOUSE
NC score	0.013251 (rank : 303)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	284	Target Neighborhood Hits	2132	Shared Neighborhood Hits	64
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_HUMAN
NC score	0.013076 (rank : 304)	θ value	0.0252991 (rank : 67)
Query Neighborhood Hits	284	Target Neighborhood Hits	1921	Shared Neighborhood Hits	60
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZFY28_HUMAN
NC score	0.012841 (rank : 305)	θ value	1.38821 (rank : 156)
Query Neighborhood Hits	284	Target Neighborhood Hits	152	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

MARK2_MOUSE
NC score	0.012802 (rank : 306)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	284	Target Neighborhood Hits	1018	Shared Neighborhood Hits	52
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

PUNC_MOUSE
NC score	0.012638 (rank : 307)	θ value	0.163984 (rank : 90)
Query Neighborhood Hits	284	Target Neighborhood Hits	501	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RB_HUMAN
NC score	0.012566 (rank : 308)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	284	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P06400, P78499, Q5VW46, Q8IZL4	Gene names	RB1
Domain Architecture
Description	Retinoblastoma-associated protein (PP110) (P105-RB) (RB).

LIMD1_MOUSE
NC score	0.012464 (rank : 309)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	284	Target Neighborhood Hits	291	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

CCR3_MOUSE
NC score	0.012400 (rank : 310)	θ value	0.62314 (rank : 117)
Query Neighborhood Hits	284	Target Neighborhood Hits	781	Shared Neighborhood Hits	10
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

MY18B_HUMAN
NC score	0.012302 (rank : 311)	θ value	0.47712 (rank : 114)
Query Neighborhood Hits	284	Target Neighborhood Hits	1299	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

SPAG1_MOUSE
NC score	0.011978 (rank : 312)	θ value	0.813845 (rank : 134)
Query Neighborhood Hits	284	Target Neighborhood Hits	218	Shared Neighborhood Hits	8
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

GAK_HUMAN
NC score	0.011672 (rank : 313)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	284	Target Neighborhood Hits	1028	Shared Neighborhood Hits	53
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

UBP6_HUMAN
NC score	0.011648 (rank : 314)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	284	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

TRIM8_MOUSE
NC score	0.011609 (rank : 315)	θ value	1.06291 (rank : 148)
Query Neighborhood Hits	284	Target Neighborhood Hits	674	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TSH1_MOUSE
NC score	0.011541 (rank : 316)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	284	Target Neighborhood Hits	675	Shared Neighborhood Hits	23
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

ZDH14_HUMAN
NC score	0.011403 (rank : 317)	θ value	1.38821 (rank : 155)
Query Neighborhood Hits	284	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZN3, Q5JS07, Q5JS08, Q6PHS4, Q8IZN2, Q9H7F1	Gene names	ZDHHC14
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP).

CUTL1_MOUSE
NC score	0.011267 (rank : 318)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	284	Target Neighborhood Hits	1620	Shared Neighborhood Hits	65
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

K0999_MOUSE
NC score	0.011214 (rank : 319)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	284	Target Neighborhood Hits	931	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

WEE1B_HUMAN
NC score	0.010914 (rank : 320)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	284	Target Neighborhood Hits	836	Shared Neighborhood Hits	37
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

CN037_HUMAN
NC score	0.010551 (rank : 321)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	284	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

B3A3_HUMAN
NC score	0.009729 (rank : 322)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	284	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

ELF4_MOUSE
NC score	0.009473 (rank : 323)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	284	Target Neighborhood Hits	191	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

M3K3_MOUSE
NC score	0.008999 (rank : 324)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	284	Target Neighborhood Hits	876	Shared Neighborhood Hits	26
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

TBX2_HUMAN
NC score	0.008631 (rank : 325)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	284	Target Neighborhood Hits	195	Shared Neighborhood Hits	26
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

HSF4_MOUSE
NC score	0.008300 (rank : 326)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	284	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0L1, Q9R0L2	Gene names	Hsf4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (mHSF4).

CLAP2_MOUSE
NC score	0.008079 (rank : 327)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	284	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

TACC1_MOUSE
NC score	0.007886 (rank : 328)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	284	Target Neighborhood Hits	667	Shared Neighborhood Hits	28
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

NFAC2_HUMAN
NC score	0.007831 (rank : 329)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	284	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

FOXN4_MOUSE
NC score	0.007800 (rank : 330)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	284	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

M3K9_HUMAN
NC score	0.007753 (rank : 331)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	284	Target Neighborhood Hits	1123	Shared Neighborhood Hits	43
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

PAPPA_HUMAN
NC score	0.006856 (rank : 332)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	284	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

GP123_HUMAN
NC score	0.006798 (rank : 333)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	284	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

RIPK1_MOUSE
NC score	0.006679 (rank : 334)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	284	Target Neighborhood Hits	874	Shared Neighborhood Hits	26
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

NFIB_HUMAN
NC score	0.006560 (rank : 335)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	284	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

FREA_HUMAN
NC score	0.006299 (rank : 336)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	284	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

CLC11_HUMAN
NC score	0.006212 (rank : 337)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	284	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y240	Gene names	CLEC11A, CLECSF3, LSLCL, SCGF
Domain Architecture
Description	C-type lectin domain family 11 member A precursor (Stem cell growth factor) (Lymphocyte secreted C-type lectin) (p47) (C-type lectin superfamily member 3).

TSH3_HUMAN
NC score	0.005921 (rank : 338)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	284	Target Neighborhood Hits	564	Shared Neighborhood Hits	21
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

RXRA_HUMAN
NC score	0.005891 (rank : 339)	θ value	0.279714 (rank : 103)
Query Neighborhood Hits	284	Target Neighborhood Hits	223	Shared Neighborhood Hits	17
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

PANK1_HUMAN
NC score	0.005830 (rank : 340)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	284	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

ITF2_HUMAN
NC score	0.005761 (rank : 341)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	284	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
NC score	0.005232 (rank : 342)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	284	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

EDD1_MOUSE
NC score	0.005184 (rank : 343)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	284	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

MYO1E_HUMAN
NC score	0.004926 (rank : 344)	θ value	0.62314 (rank : 122)
Query Neighborhood Hits	284	Target Neighborhood Hits	293	Shared Neighborhood Hits	11
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

SALL2_MOUSE
NC score	0.004898 (rank : 345)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	284	Target Neighborhood Hits	836	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

DDX24_MOUSE
NC score	0.004814 (rank : 346)	θ value	1.06291 (rank : 143)
Query Neighborhood Hits	284	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

GLI2_HUMAN
NC score	0.004694 (rank : 347)	θ value	0.279714 (rank : 100)
Query Neighborhood Hits	284	Target Neighborhood Hits	971	Shared Neighborhood Hits	48
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

STML1_MOUSE
NC score	0.004425 (rank : 348)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	284	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CI66, Q8BLA3	Gene names	Stoml1
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1).

KLF17_HUMAN
NC score	0.003945 (rank : 349)	θ value	0.62314 (rank : 121)
Query Neighborhood Hits	284	Target Neighborhood Hits	882	Shared Neighborhood Hits	45
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

HXB3_HUMAN
NC score	0.003793 (rank : 350)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	284	Target Neighborhood Hits	559	Shared Neighborhood Hits	31
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

COE3_HUMAN
NC score	0.003729 (rank : 351)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	284	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

NOTC3_HUMAN
NC score	0.003375 (rank : 352)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	284	Target Neighborhood Hits	1062	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

BAI2_HUMAN
NC score	0.003343 (rank : 353)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	284	Target Neighborhood Hits	332	Shared Neighborhood Hits	18
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

PO3F4_HUMAN
NC score	0.002995 (rank : 354)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	284	Target Neighborhood Hits	297	Shared Neighborhood Hits	8
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

SALL2_HUMAN
NC score	0.002444 (rank : 355)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	284	Target Neighborhood Hits	835	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

C1QR1_HUMAN
NC score	0.002297 (rank : 356)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	284	Target Neighborhood Hits	493	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

ZN217_HUMAN
NC score	0.001799 (rank : 357)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	284	Target Neighborhood Hits	905	Shared Neighborhood Hits	40
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

NOTC2_MOUSE
NC score	0.001579 (rank : 358)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	284	Target Neighborhood Hits	1069	Shared Neighborhood Hits	42
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

GLIS3_MOUSE
NC score	0.001007 (rank : 359)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	284	Target Neighborhood Hits	861	Shared Neighborhood Hits	41
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

TAAR1_HUMAN
NC score	-0.000142 (rank : 360)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	284	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

CO2_HUMAN
NC score	-0.001056 (rank : 361)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	284	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

HIC1_HUMAN
NC score	-0.002338 (rank : 362)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	284	Target Neighborhood Hits	838	Shared Neighborhood Hits	43
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HIC1_MOUSE
NC score	-0.002916 (rank : 363)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	284	Target Neighborhood Hits	863	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).