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Network neighborhood for query Sequence : CBL_HUMAN

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CBL_HUMAN
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CBLB_HUMAN
θ value	0 (rank : 1)	NC score	0.954863 (rank : 3)
Query Neighborhood Hits	353	Target Neighborhood Hits	261	Shared Neighborhood Hits	193
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0 (rank : 2)	NC score	0.954009 (rank : 4)
Query Neighborhood Hits	353	Target Neighborhood Hits	277	Shared Neighborhood Hits	194
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBL_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	353	Target Neighborhood Hits	353	Shared Neighborhood Hits	353
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0 (rank : 4)	NC score	0.970121 (rank : 2)
Query Neighborhood Hits	353	Target Neighborhood Hits	426	Shared Neighborhood Hits	277
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBLC_HUMAN
θ value	2.61662e-116 (rank : 5)	NC score	0.935161 (rank : 5)
Query Neighborhood Hits	353	Target Neighborhood Hits	173	Shared Neighborhood Hits	151
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	2.61662e-116 (rank : 6)	NC score	0.932891 (rank : 6)
Query Neighborhood Hits	353	Target Neighborhood Hits	186	Shared Neighborhood Hits	156
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RNF5_HUMAN
θ value	2.88788e-06 (rank : 7)	NC score	0.435679 (rank : 10)
Query Neighborhood Hits	353	Target Neighborhood Hits	206	Shared Neighborhood Hits	155
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RN185_HUMAN
θ value	2.44474e-05 (rank : 8)	NC score	0.446706 (rank : 8)
Query Neighborhood Hits	353	Target Neighborhood Hits	213	Shared Neighborhood Hits	160
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	2.44474e-05 (rank : 9)	NC score	0.444946 (rank : 9)
Query Neighborhood Hits	353	Target Neighborhood Hits	211	Shared Neighborhood Hits	158
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

PEX10_HUMAN
θ value	3.19293e-05 (rank : 10)	NC score	0.449416 (rank : 7)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	176
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RNF5_MOUSE
θ value	3.19293e-05 (rank : 11)	NC score	0.425463 (rank : 11)
Query Neighborhood Hits	353	Target Neighborhood Hits	206	Shared Neighborhood Hits	153
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

BIRC3_MOUSE
θ value	0.000786445 (rank : 12)	NC score	0.213173 (rank : 53)
Query Neighborhood Hits	353	Target Neighborhood Hits	113	Shared Neighborhood Hits	74
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

ZN438_HUMAN
θ value	0.000786445 (rank : 13)	NC score	0.024563 (rank : 386)
Query Neighborhood Hits	353	Target Neighborhood Hits	906	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

BIRC3_HUMAN
θ value	0.00102713 (rank : 14)	NC score	0.214631 (rank : 51)
Query Neighborhood Hits	353	Target Neighborhood Hits	133	Shared Neighborhood Hits	85
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC2_MOUSE
θ value	0.00175202 (rank : 15)	NC score	0.204495 (rank : 63)
Query Neighborhood Hits	353	Target Neighborhood Hits	137	Shared Neighborhood Hits	79
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

ZN364_HUMAN
θ value	0.00175202 (rank : 16)	NC score	0.268534 (rank : 22)
Query Neighborhood Hits	353	Target Neighborhood Hits	140	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

AMFR2_HUMAN
θ value	0.00228821 (rank : 17)	NC score	0.310371 (rank : 15)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	0.00228821 (rank : 18)	NC score	0.312413 (rank : 14)
Query Neighborhood Hits	353	Target Neighborhood Hits	208	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

BIRC2_HUMAN
θ value	0.00228821 (rank : 19)	NC score	0.200449 (rank : 66)
Query Neighborhood Hits	353	Target Neighborhood Hits	142	Shared Neighborhood Hits	82
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

PML_HUMAN
θ value	0.00228821 (rank : 20)	NC score	0.232551 (rank : 44)
Query Neighborhood Hits	353	Target Neighborhood Hits	248	Shared Neighborhood Hits	96
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RNF8_HUMAN
θ value	0.00228821 (rank : 21)	NC score	0.264101 (rank : 25)
Query Neighborhood Hits	353	Target Neighborhood Hits	622	Shared Neighborhood Hits	172
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

SRRM2_MOUSE
θ value	0.00228821 (rank : 22)	NC score	0.097262 (rank : 207)
Query Neighborhood Hits	353	Target Neighborhood Hits	1470	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TRI65_HUMAN
θ value	0.00228821 (rank : 23)	NC score	0.269668 (rank : 21)
Query Neighborhood Hits	353	Target Neighborhood Hits	330	Shared Neighborhood Hits	169
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CHFR_HUMAN
θ value	0.00390308 (rank : 24)	NC score	0.308418 (rank : 16)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	143
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	0.00390308 (rank : 25)	NC score	0.306216 (rank : 17)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	146
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN141_HUMAN
θ value	0.00390308 (rank : 26)	NC score	0.321736 (rank : 12)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.00509761 (rank : 27)	NC score	0.320017 (rank : 13)
Query Neighborhood Hits	353	Target Neighborhood Hits	200	Shared Neighborhood Hits	135
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RNF8_MOUSE
θ value	0.00509761 (rank : 28)	NC score	0.265962 (rank : 24)
Query Neighborhood Hits	353	Target Neighborhood Hits	618	Shared Neighborhood Hits	174
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI15_HUMAN
θ value	0.00665767 (rank : 29)	NC score	0.181327 (rank : 88)
Query Neighborhood Hits	353	Target Neighborhood Hits	395	Shared Neighborhood Hits	131
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRIM2_HUMAN
θ value	0.00665767 (rank : 30)	NC score	0.244018 (rank : 35)
Query Neighborhood Hits	353	Target Neighborhood Hits	330	Shared Neighborhood Hits	158
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.00665767 (rank : 31)	NC score	0.243250 (rank : 36)
Query Neighborhood Hits	353	Target Neighborhood Hits	331	Shared Neighborhood Hits	156
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

BIRC7_HUMAN
θ value	0.00869519 (rank : 32)	NC score	0.276694 (rank : 19)
Query Neighborhood Hits	353	Target Neighborhood Hits	185	Shared Neighborhood Hits	124
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

SRRM2_HUMAN
θ value	0.00869519 (rank : 33)	NC score	0.093481 (rank : 212)
Query Neighborhood Hits	353	Target Neighborhood Hits	1296	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRI39_HUMAN
θ value	0.00869519 (rank : 34)	NC score	0.191774 (rank : 76)
Query Neighborhood Hits	353	Target Neighborhood Hits	693	Shared Neighborhood Hits	180
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.00869519 (rank : 35)	NC score	0.189988 (rank : 78)
Query Neighborhood Hits	353	Target Neighborhood Hits	691	Shared Neighborhood Hits	177
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI56_HUMAN
θ value	0.00869519 (rank : 36)	NC score	0.248665 (rank : 30)
Query Neighborhood Hits	353	Target Neighborhood Hits	339	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

MILK1_MOUSE
θ value	0.0113563 (rank : 37)	NC score	0.061584 (rank : 304)
Query Neighborhood Hits	353	Target Neighborhood Hits	788	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

RN169_HUMAN
θ value	0.0113563 (rank : 38)	NC score	0.277530 (rank : 18)
Query Neighborhood Hits	353	Target Neighborhood Hits	203	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TRI40_HUMAN
θ value	0.0113563 (rank : 39)	NC score	0.267674 (rank : 23)
Query Neighborhood Hits	353	Target Neighborhood Hits	279	Shared Neighborhood Hits	148
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

RTN4_MOUSE
θ value	0.0148317 (rank : 40)	NC score	0.043819 (rank : 351)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

TRI37_HUMAN
θ value	0.0148317 (rank : 41)	NC score	0.241379 (rank : 41)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	120
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	0.0148317 (rank : 42)	NC score	0.241848 (rank : 39)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	121
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

ZN364_MOUSE
θ value	0.0148317 (rank : 43)	NC score	0.245198 (rank : 34)
Query Neighborhood Hits	353	Target Neighborhood Hits	140	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZN575_HUMAN
θ value	0.0148317 (rank : 44)	NC score	0.006962 (rank : 450)
Query Neighborhood Hits	353	Target Neighborhood Hits	739	Shared Neighborhood Hits	23
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

TRI25_MOUSE
θ value	0.0193708 (rank : 45)	NC score	0.217756 (rank : 50)
Query Neighborhood Hits	353	Target Neighborhood Hits	446	Shared Neighborhood Hits	165
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

GGA3_MOUSE
θ value	0.0252991 (rank : 46)	NC score	0.032997 (rank : 366)
Query Neighborhood Hits	353	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

SMRA3_MOUSE
θ value	0.0252991 (rank : 47)	NC score	0.167263 (rank : 109)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	144
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RN126_MOUSE
θ value	0.0330416 (rank : 48)	NC score	0.232643 (rank : 43)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	90
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN167_MOUSE
θ value	0.0330416 (rank : 49)	NC score	0.242005 (rank : 38)
Query Neighborhood Hits	353	Target Neighborhood Hits	157	Shared Neighborhood Hits	95
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

TRI25_HUMAN
θ value	0.0330416 (rank : 50)	NC score	0.208825 (rank : 57)
Query Neighborhood Hits	353	Target Neighborhood Hits	472	Shared Neighborhood Hits	153
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI65_MOUSE
θ value	0.0330416 (rank : 51)	NC score	0.248740 (rank : 29)
Query Neighborhood Hits	353	Target Neighborhood Hits	340	Shared Neighborhood Hits	172
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

DZIP3_MOUSE
θ value	0.0431538 (rank : 52)	NC score	0.155876 (rank : 133)
Query Neighborhood Hits	353	Target Neighborhood Hits	414	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

HCN4_MOUSE
θ value	0.0431538 (rank : 53)	NC score	0.043883 (rank : 350)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MYLIP_HUMAN
θ value	0.0431538 (rank : 54)	NC score	0.130500 (rank : 161)
Query Neighborhood Hits	353	Target Neighborhood Hits	162	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PZRN3_HUMAN
θ value	0.0431538 (rank : 55)	NC score	0.157636 (rank : 127)
Query Neighborhood Hits	353	Target Neighborhood Hits	461	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.0431538 (rank : 56)	NC score	0.157774 (rank : 126)
Query Neighborhood Hits	353	Target Neighborhood Hits	447	Shared Neighborhood Hits	155
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RN168_MOUSE
θ value	0.0431538 (rank : 57)	NC score	0.260676 (rank : 27)
Query Neighborhood Hits	353	Target Neighborhood Hits	440	Shared Neighborhood Hits	154
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF13_MOUSE
θ value	0.0431538 (rank : 58)	NC score	0.225641 (rank : 46)
Query Neighborhood Hits	353	Target Neighborhood Hits	164	Shared Neighborhood Hits	95
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

TRI56_MOUSE
θ value	0.0431538 (rank : 59)	NC score	0.226227 (rank : 45)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	132
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI60_HUMAN
θ value	0.0431538 (rank : 60)	NC score	0.187516 (rank : 81)
Query Neighborhood Hits	353	Target Neighborhood Hits	357	Shared Neighborhood Hits	155
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRIM3_MOUSE
θ value	0.0431538 (rank : 61)	NC score	0.224572 (rank : 48)
Query Neighborhood Hits	353	Target Neighborhood Hits	351	Shared Neighborhood Hits	147
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

GOLI_HUMAN
θ value	0.0563607 (rank : 62)	NC score	0.209006 (rank : 56)
Query Neighborhood Hits	353	Target Neighborhood Hits	137	Shared Neighborhood Hits	70
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RN168_HUMAN
θ value	0.0563607 (rank : 63)	NC score	0.270466 (rank : 20)
Query Neighborhood Hits	353	Target Neighborhood Hits	370	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRIM3_HUMAN
θ value	0.0563607 (rank : 64)	NC score	0.224891 (rank : 47)
Query Neighborhood Hits	353	Target Neighborhood Hits	357	Shared Neighborhood Hits	147
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

DNMBP_MOUSE
θ value	0.0736092 (rank : 65)	NC score	0.023537 (rank : 390)
Query Neighborhood Hits	353	Target Neighborhood Hits	435	Shared Neighborhood Hits	23
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

GOLI_MOUSE
θ value	0.0736092 (rank : 66)	NC score	0.206242 (rank : 61)
Query Neighborhood Hits	353	Target Neighborhood Hits	134	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

NEURL_MOUSE
θ value	0.0736092 (rank : 67)	NC score	0.198192 (rank : 69)
Query Neighborhood Hits	353	Target Neighborhood Hits	106	Shared Neighborhood Hits	72
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

PML_MOUSE
θ value	0.0736092 (rank : 68)	NC score	0.193648 (rank : 75)
Query Neighborhood Hits	353	Target Neighborhood Hits	246	Shared Neighborhood Hits	90
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PZRN4_HUMAN
θ value	0.0736092 (rank : 69)	NC score	0.156852 (rank : 130)
Query Neighborhood Hits	353	Target Neighborhood Hits	438	Shared Neighborhood Hits	153
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RN167_HUMAN
θ value	0.0736092 (rank : 70)	NC score	0.238359 (rank : 42)
Query Neighborhood Hits	353	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

LNX1_MOUSE
θ value	0.0961366 (rank : 71)	NC score	0.130492 (rank : 162)
Query Neighborhood Hits	353	Target Neighborhood Hits	377	Shared Neighborhood Hits	131
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MGRN1_HUMAN
θ value	0.0961366 (rank : 72)	NC score	0.208327 (rank : 59)
Query Neighborhood Hits	353	Target Neighborhood Hits	192	Shared Neighborhood Hits	108
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

RN133_HUMAN
θ value	0.0961366 (rank : 73)	NC score	0.213976 (rank : 52)
Query Neighborhood Hits	353	Target Neighborhood Hits	108	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RN165_HUMAN
θ value	0.0961366 (rank : 74)	NC score	0.257505 (rank : 28)
Query Neighborhood Hits	353	Target Neighborhood Hits	151	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RNF13_HUMAN
θ value	0.0961366 (rank : 75)	NC score	0.218888 (rank : 49)
Query Neighborhood Hits	353	Target Neighborhood Hits	147	Shared Neighborhood Hits	91
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

TRI35_HUMAN
θ value	0.0961366 (rank : 76)	NC score	0.204649 (rank : 62)
Query Neighborhood Hits	353	Target Neighborhood Hits	382	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

YLPM1_HUMAN
θ value	0.0961366 (rank : 77)	NC score	0.074913 (rank : 251)
Query Neighborhood Hits	353	Target Neighborhood Hits	670	Shared Neighborhood Hits	67
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CN032_MOUSE
θ value	0.125558 (rank : 78)	NC score	0.064762 (rank : 290)
Query Neighborhood Hits	353	Target Neighborhood Hits	233	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CSKI1_MOUSE
θ value	0.125558 (rank : 79)	NC score	0.032881 (rank : 368)
Query Neighborhood Hits	353	Target Neighborhood Hits	1031	Shared Neighborhood Hits	88
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LNX1_HUMAN
θ value	0.125558 (rank : 80)	NC score	0.128590 (rank : 165)
Query Neighborhood Hits	353	Target Neighborhood Hits	379	Shared Neighborhood Hits	143
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MGRN1_MOUSE
θ value	0.125558 (rank : 81)	NC score	0.209639 (rank : 55)
Query Neighborhood Hits	353	Target Neighborhood Hits	149	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MLL2_HUMAN
θ value	0.125558 (rank : 82)	NC score	0.052623 (rank : 329)
Query Neighborhood Hits	353	Target Neighborhood Hits	1788	Shared Neighborhood Hits	111
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYLIP_MOUSE
θ value	0.125558 (rank : 83)	NC score	0.111302 (rank : 179)
Query Neighborhood Hits	353	Target Neighborhood Hits	139	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NHLC1_MOUSE
θ value	0.125558 (rank : 84)	NC score	0.211972 (rank : 54)
Query Neighborhood Hits	353	Target Neighborhood Hits	103	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRAIP_HUMAN
θ value	0.125558 (rank : 85)	NC score	0.136740 (rank : 152)
Query Neighborhood Hits	353	Target Neighborhood Hits	780	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	0.125558 (rank : 86)	NC score	0.130638 (rank : 160)
Query Neighborhood Hits	353	Target Neighborhood Hits	745	Shared Neighborhood Hits	98
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

NEUL1_HUMAN
θ value	0.163984 (rank : 87)	NC score	0.191302 (rank : 77)
Query Neighborhood Hits	353	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

RN166_HUMAN
θ value	0.163984 (rank : 88)	NC score	0.241680 (rank : 40)
Query Neighborhood Hits	353	Target Neighborhood Hits	240	Shared Neighborhood Hits	142
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	0.163984 (rank : 89)	NC score	0.247328 (rank : 31)
Query Neighborhood Hits	353	Target Neighborhood Hits	248	Shared Neighborhood Hits	144
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF37_MOUSE
θ value	0.163984 (rank : 90)	NC score	0.160348 (rank : 120)
Query Neighborhood Hits	353	Target Neighborhood Hits	102	Shared Neighborhood Hits	52
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

WNK4_HUMAN
θ value	0.163984 (rank : 91)	NC score	0.011116 (rank : 432)
Query Neighborhood Hits	353	Target Neighborhood Hits	1043	Shared Neighborhood Hits	41
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CCD95_HUMAN
θ value	0.21417 (rank : 92)	NC score	0.081165 (rank : 235)
Query Neighborhood Hits	353	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

NACAM_MOUSE
θ value	0.21417 (rank : 93)	NC score	0.068509 (rank : 277)
Query Neighborhood Hits	353	Target Neighborhood Hits	1866	Shared Neighborhood Hits	122
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RFFL_HUMAN
θ value	0.21417 (rank : 94)	NC score	0.176087 (rank : 97)
Query Neighborhood Hits	353	Target Neighborhood Hits	175	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	0.21417 (rank : 95)	NC score	0.175208 (rank : 98)
Query Neighborhood Hits	353	Target Neighborhood Hits	145	Shared Neighborhood Hits	76
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

TENX_HUMAN
θ value	0.21417 (rank : 96)	NC score	0.009817 (rank : 437)
Query Neighborhood Hits	353	Target Neighborhood Hits	789	Shared Neighborhood Hits	14
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TRI26_HUMAN
θ value	0.21417 (rank : 97)	NC score	0.198647 (rank : 68)
Query Neighborhood Hits	353	Target Neighborhood Hits	335	Shared Neighborhood Hits	161
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI32_HUMAN
θ value	0.21417 (rank : 98)	NC score	0.198152 (rank : 70)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	119
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	0.21417 (rank : 99)	NC score	0.197126 (rank : 71)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	119
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

DZIP3_HUMAN
θ value	0.279714 (rank : 100)	NC score	0.144280 (rank : 144)
Query Neighborhood Hits	353	Target Neighborhood Hits	399	Shared Neighborhood Hits	82
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RN123_MOUSE
θ value	0.279714 (rank : 101)	NC score	0.136228 (rank : 154)
Query Neighborhood Hits	353	Target Neighborhood Hits	174	Shared Neighborhood Hits	96
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN125_HUMAN
θ value	0.279714 (rank : 102)	NC score	0.261397 (rank : 26)
Query Neighborhood Hits	353	Target Neighborhood Hits	230	Shared Neighborhood Hits	150
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

SEPT9_MOUSE
θ value	0.279714 (rank : 103)	NC score	0.025762 (rank : 382)
Query Neighborhood Hits	353	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

TRI35_MOUSE
θ value	0.279714 (rank : 104)	NC score	0.200874 (rank : 64)
Query Neighborhood Hits	353	Target Neighborhood Hits	465	Shared Neighborhood Hits	160
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI62_HUMAN
θ value	0.279714 (rank : 105)	NC score	0.155518 (rank : 134)
Query Neighborhood Hits	353	Target Neighborhood Hits	584	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	0.279714 (rank : 106)	NC score	0.158987 (rank : 122)
Query Neighborhood Hits	353	Target Neighborhood Hits	478	Shared Neighborhood Hits	141
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

WASL_MOUSE
θ value	0.279714 (rank : 107)	NC score	0.054632 (rank : 324)
Query Neighborhood Hits	353	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZN575_MOUSE
θ value	0.279714 (rank : 108)	NC score	0.003731 (rank : 456)
Query Neighborhood Hits	353	Target Neighborhood Hits	715	Shared Neighborhood Hits	20
SwissProt Accessions	Q3TXZ1	Gene names	Znf575, Zfp575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

AFF4_HUMAN
θ value	0.365318 (rank : 109)	NC score	0.036501 (rank : 361)
Query Neighborhood Hits	353	Target Neighborhood Hits	611	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

BIRC4_HUMAN
θ value	0.365318 (rank : 110)	NC score	0.148326 (rank : 143)
Query Neighborhood Hits	353	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

CBP_MOUSE
θ value	0.365318 (rank : 111)	NC score	0.060421 (rank : 309)
Query Neighborhood Hits	353	Target Neighborhood Hits	1051	Shared Neighborhood Hits	88
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CO039_HUMAN
θ value	0.365318 (rank : 112)	NC score	0.058954 (rank : 314)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

RN123_HUMAN
θ value	0.365318 (rank : 113)	NC score	0.131968 (rank : 158)
Query Neighborhood Hits	353	Target Neighborhood Hits	175	Shared Neighborhood Hits	96
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN125_MOUSE
θ value	0.365318 (rank : 114)	NC score	0.242525 (rank : 37)
Query Neighborhood Hits	353	Target Neighborhood Hits	220	Shared Neighborhood Hits	137
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI11_HUMAN
θ value	0.365318 (rank : 115)	NC score	0.160412 (rank : 119)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	145
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	0.365318 (rank : 116)	NC score	0.159841 (rank : 121)
Query Neighborhood Hits	353	Target Neighborhood Hits	329	Shared Neighborhood Hits	149
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

ZN313_HUMAN
θ value	0.365318 (rank : 117)	NC score	0.246695 (rank : 33)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN668_HUMAN
θ value	0.365318 (rank : 118)	NC score	-0.000033 (rank : 462)
Query Neighborhood Hits	353	Target Neighborhood Hits	761	Shared Neighborhood Hits	19
SwissProt Accessions	Q96K58, Q59EV1, Q8N669, Q9H8L4	Gene names	ZNF668
Domain Architecture	No domain graphic available
Description	Zinc finger protein 668.

BRD4_MOUSE
θ value	0.47712 (rank : 119)	NC score	0.032775 (rank : 370)
Query Neighborhood Hits	353	Target Neighborhood Hits	845	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CO039_MOUSE
θ value	0.47712 (rank : 120)	NC score	0.090753 (rank : 216)
Query Neighborhood Hits	353	Target Neighborhood Hits	445	Shared Neighborhood Hits	65
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

RKHD1_HUMAN
θ value	0.47712 (rank : 121)	NC score	0.207311 (rank : 60)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	79
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RO52_MOUSE
θ value	0.47712 (rank : 122)	NC score	0.165153 (rank : 112)
Query Neighborhood Hits	353	Target Neighborhood Hits	360	Shared Neighborhood Hits	154
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

SGIP1_HUMAN
θ value	0.47712 (rank : 123)	NC score	0.067390 (rank : 280)
Query Neighborhood Hits	353	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TITIN_HUMAN
θ value	0.47712 (rank : 124)	NC score	0.007162 (rank : 449)
Query Neighborhood Hits	353	Target Neighborhood Hits	2923	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRI30_MOUSE
θ value	0.47712 (rank : 125)	NC score	0.168967 (rank : 107)
Query Neighborhood Hits	353	Target Neighborhood Hits	434	Shared Neighborhood Hits	139
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI50_HUMAN
θ value	0.47712 (rank : 126)	NC score	0.177089 (rank : 95)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	149
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ZN313_MOUSE
θ value	0.47712 (rank : 127)	NC score	0.246872 (rank : 32)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	159
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

AF9_HUMAN
θ value	0.62314 (rank : 128)	NC score	0.031175 (rank : 372)
Query Neighborhood Hits	353	Target Neighborhood Hits	202	Shared Neighborhood Hits	14
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

AFF1_MOUSE
θ value	0.62314 (rank : 129)	NC score	0.046867 (rank : 344)
Query Neighborhood Hits	353	Target Neighborhood Hits	351	Shared Neighborhood Hits	37
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ALEX_MOUSE
θ value	0.62314 (rank : 130)	NC score	0.066126 (rank : 283)
Query Neighborhood Hits	353	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CJ012_HUMAN
θ value	0.62314 (rank : 131)	NC score	0.061918 (rank : 300)
Query Neighborhood Hits	353	Target Neighborhood Hits	467	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

RING1_HUMAN
θ value	0.62314 (rank : 132)	NC score	0.189870 (rank : 79)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	124
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.62314 (rank : 133)	NC score	0.187862 (rank : 80)
Query Neighborhood Hits	353	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	0.62314 (rank : 134)	NC score	0.178249 (rank : 93)
Query Neighborhood Hits	353	Target Neighborhood Hits	201	Shared Neighborhood Hits	121
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.62314 (rank : 135)	NC score	0.178360 (rank : 92)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	121
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN103_HUMAN
θ value	0.62314 (rank : 136)	NC score	0.170746 (rank : 104)
Query Neighborhood Hits	353	Target Neighborhood Hits	153	Shared Neighborhood Hits	90
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	0.62314 (rank : 137)	NC score	0.170479 (rank : 105)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN126_HUMAN
θ value	0.62314 (rank : 138)	NC score	0.195293 (rank : 73)
Query Neighborhood Hits	353	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

SPEG_MOUSE
θ value	0.62314 (rank : 139)	NC score	0.014362 (rank : 416)
Query Neighborhood Hits	353	Target Neighborhood Hits	1959	Shared Neighborhood Hits	96
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRI17_HUMAN
θ value	0.62314 (rank : 140)	NC score	0.157333 (rank : 128)
Query Neighborhood Hits	353	Target Neighborhood Hits	318	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI26_MOUSE
θ value	0.62314 (rank : 141)	NC score	0.196749 (rank : 72)
Query Neighborhood Hits	353	Target Neighborhood Hits	339	Shared Neighborhood Hits	163
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI68_HUMAN
θ value	0.62314 (rank : 142)	NC score	0.157893 (rank : 125)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	135
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI68_MOUSE
θ value	0.62314 (rank : 143)	NC score	0.164465 (rank : 113)
Query Neighborhood Hits	353	Target Neighborhood Hits	356	Shared Neighborhood Hits	147
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

BIRC4_MOUSE
θ value	0.813845 (rank : 144)	NC score	0.143098 (rank : 146)
Query Neighborhood Hits	353	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

CD2L7_HUMAN
θ value	0.813845 (rank : 145)	NC score	0.007321 (rank : 448)
Query Neighborhood Hits	353	Target Neighborhood Hits	1275	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

K1210_HUMAN
θ value	0.813845 (rank : 146)	NC score	0.042213 (rank : 353)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

MAST4_HUMAN
θ value	0.813845 (rank : 147)	NC score	0.011486 (rank : 431)
Query Neighborhood Hits	353	Target Neighborhood Hits	1804	Shared Neighborhood Hits	98
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MIB1_MOUSE
θ value	0.813845 (rank : 148)	NC score	0.068829 (rank : 276)
Query Neighborhood Hits	353	Target Neighborhood Hits	471	Shared Neighborhood Hits	97
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RB6I2_HUMAN
θ value	0.813845 (rank : 149)	NC score	0.019008 (rank : 406)
Query Neighborhood Hits	353	Target Neighborhood Hits	1584	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	0.813845 (rank : 150)	NC score	0.019164 (rank : 405)
Query Neighborhood Hits	353	Target Neighborhood Hits	1433	Shared Neighborhood Hits	51
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RIN3_MOUSE
θ value	0.813845 (rank : 151)	NC score	0.041980 (rank : 354)
Query Neighborhood Hits	353	Target Neighborhood Hits	239	Shared Neighborhood Hits	30
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RNF24_MOUSE
θ value	0.813845 (rank : 152)	NC score	0.172237 (rank : 100)
Query Neighborhood Hits	353	Target Neighborhood Hits	124	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF26_HUMAN
θ value	0.813845 (rank : 153)	NC score	0.199777 (rank : 67)
Query Neighborhood Hits	353	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RO52_HUMAN
θ value	0.813845 (rank : 154)	NC score	0.163936 (rank : 114)
Query Neighborhood Hits	353	Target Neighborhood Hits	419	Shared Neighborhood Hits	165
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI13_MOUSE
θ value	0.813845 (rank : 155)	NC score	0.194258 (rank : 74)
Query Neighborhood Hits	353	Target Neighborhood Hits	282	Shared Neighborhood Hits	149
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI43_HUMAN
θ value	0.813845 (rank : 156)	NC score	0.168536 (rank : 108)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	148
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI60_MOUSE
θ value	0.813845 (rank : 157)	NC score	0.162785 (rank : 115)
Query Neighborhood Hits	353	Target Neighborhood Hits	240	Shared Neighborhood Hits	126
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

WASL_HUMAN
θ value	0.813845 (rank : 158)	NC score	0.044911 (rank : 349)
Query Neighborhood Hits	353	Target Neighborhood Hits	312	Shared Neighborhood Hits	36
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ATBF1_HUMAN
θ value	1.06291 (rank : 159)	NC score	0.017610 (rank : 409)
Query Neighborhood Hits	353	Target Neighborhood Hits	1547	Shared Neighborhood Hits	58
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BRE1B_HUMAN
θ value	1.06291 (rank : 160)	NC score	0.072054 (rank : 260)
Query Neighborhood Hits	353	Target Neighborhood Hits	1040	Shared Neighborhood Hits	130
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	1.06291 (rank : 161)	NC score	0.073137 (rank : 256)
Query Neighborhood Hits	353	Target Neighborhood Hits	970	Shared Neighborhood Hits	126
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

H2B2D_HUMAN
θ value	1.06291 (rank : 162)	NC score	0.013818 (rank : 418)
Query Neighborhood Hits	353	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DRA6	Gene names	HIST2H2BD
Domain Architecture	No domain graphic available
Description	Histone H2B type 2-D.

KCNB2_HUMAN
θ value	1.06291 (rank : 163)	NC score	0.007772 (rank : 447)
Query Neighborhood Hits	353	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

MAGE1_HUMAN
θ value	1.06291 (rank : 164)	NC score	0.044954 (rank : 348)
Query Neighborhood Hits	353	Target Neighborhood Hits	1389	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MUC1_HUMAN
θ value	1.06291 (rank : 165)	NC score	0.046557 (rank : 345)
Query Neighborhood Hits	353	Target Neighborhood Hits	975	Shared Neighborhood Hits	82
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NHLC1_HUMAN
θ value	1.06291 (rank : 166)	NC score	0.167097 (rank : 110)
Query Neighborhood Hits	353	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

REPS1_HUMAN
θ value	1.06291 (rank : 167)	NC score	0.049764 (rank : 341)
Query Neighborhood Hits	353	Target Neighborhood Hits	205	Shared Neighborhood Hits	23
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RN122_MOUSE
θ value	1.06291 (rank : 168)	NC score	0.176373 (rank : 96)
Query Neighborhood Hits	353	Target Neighborhood Hits	121	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF24_HUMAN
θ value	1.06291 (rank : 169)	NC score	0.169925 (rank : 106)
Query Neighborhood Hits	353	Target Neighborhood Hits	122	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

SCAP_HUMAN
θ value	1.06291 (rank : 170)	NC score	0.025749 (rank : 383)
Query Neighborhood Hits	353	Target Neighborhood Hits	368	Shared Neighborhood Hits	31
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SEPT9_HUMAN
θ value	1.06291 (rank : 171)	NC score	0.037976 (rank : 359)
Query Neighborhood Hits	353	Target Neighborhood Hits	706	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TRI13_HUMAN
θ value	1.06291 (rank : 172)	NC score	0.186808 (rank : 84)
Query Neighborhood Hits	353	Target Neighborhood Hits	274	Shared Neighborhood Hits	147
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI59_MOUSE
θ value	1.06291 (rank : 173)	NC score	0.174045 (rank : 99)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	143
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

WASIP_MOUSE
θ value	1.06291 (rank : 174)	NC score	0.071650 (rank : 262)
Query Neighborhood Hits	353	Target Neighborhood Hits	392	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ADA29_HUMAN
θ value	1.38821 (rank : 175)	NC score	0.009011 (rank : 442)
Query Neighborhood Hits	353	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ALEX_HUMAN
θ value	1.38821 (rank : 176)	NC score	0.070153 (rank : 271)
Query Neighborhood Hits	353	Target Neighborhood Hits	361	Shared Neighborhood Hits	46
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BIRC8_HUMAN
θ value	1.38821 (rank : 177)	NC score	0.161420 (rank : 117)
Query Neighborhood Hits	353	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BSN_HUMAN
θ value	1.38821 (rank : 178)	NC score	0.046432 (rank : 346)
Query Neighborhood Hits	353	Target Neighborhood Hits	1537	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CEND3_MOUSE
θ value	1.38821 (rank : 179)	NC score	0.011010 (rank : 434)
Query Neighborhood Hits	353	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CSKI1_HUMAN
θ value	1.38821 (rank : 180)	NC score	0.028299 (rank : 378)
Query Neighborhood Hits	353	Target Neighborhood Hits	997	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EFS_HUMAN
θ value	1.38821 (rank : 181)	NC score	0.038716 (rank : 356)
Query Neighborhood Hits	353	Target Neighborhood Hits	348	Shared Neighborhood Hits	33
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EPN1_HUMAN
θ value	1.38821 (rank : 182)	NC score	0.020853 (rank : 398)
Query Neighborhood Hits	353	Target Neighborhood Hits	206	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

HCN4_HUMAN
θ value	1.38821 (rank : 183)	NC score	0.029189 (rank : 377)
Query Neighborhood Hits	353	Target Neighborhood Hits	303	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

MDC1_HUMAN
θ value	1.38821 (rank : 184)	NC score	0.058926 (rank : 315)
Query Neighborhood Hits	353	Target Neighborhood Hits	1446	Shared Neighborhood Hits	99
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RAI1_MOUSE
θ value	1.38821 (rank : 185)	NC score	0.031110 (rank : 374)
Query Neighborhood Hits	353	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TRI59_HUMAN
θ value	1.38821 (rank : 186)	NC score	0.171847 (rank : 102)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	144
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

WASIP_HUMAN
θ value	1.38821 (rank : 187)	NC score	0.066653 (rank : 282)
Query Neighborhood Hits	353	Target Neighborhood Hits	458	Shared Neighborhood Hits	53
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ANR11_HUMAN
θ value	1.81305 (rank : 188)	NC score	0.021198 (rank : 397)
Query Neighborhood Hits	353	Target Neighborhood Hits	1289	Shared Neighborhood Hits	70
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CS016_HUMAN
θ value	1.81305 (rank : 189)	NC score	0.050050 (rank : 338)
Query Neighborhood Hits	353	Target Neighborhood Hits	310	Shared Neighborhood Hits	47
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

E2AK4_HUMAN
θ value	1.81305 (rank : 190)	NC score	0.003772 (rank : 455)
Query Neighborhood Hits	353	Target Neighborhood Hits	1012	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

RAPH1_HUMAN
θ value	1.81305 (rank : 191)	NC score	0.058179 (rank : 316)
Query Neighborhood Hits	353	Target Neighborhood Hits	593	Shared Neighborhood Hits	59
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

REPS1_MOUSE
θ value	1.81305 (rank : 192)	NC score	0.041909 (rank : 355)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RNF34_HUMAN
θ value	1.81305 (rank : 193)	NC score	0.149451 (rank : 140)
Query Neighborhood Hits	353	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	1.81305 (rank : 194)	NC score	0.149705 (rank : 139)
Query Neighborhood Hits	353	Target Neighborhood Hits	160	Shared Neighborhood Hits	83
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

SMRA3_HUMAN
θ value	1.81305 (rank : 195)	NC score	0.134931 (rank : 155)
Query Neighborhood Hits	353	Target Neighborhood Hits	265	Shared Neighborhood Hits	143
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI10_HUMAN
θ value	1.81305 (rank : 196)	NC score	0.166235 (rank : 111)
Query Neighborhood Hits	353	Target Neighborhood Hits	315	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI10_MOUSE
θ value	1.81305 (rank : 197)	NC score	0.161158 (rank : 118)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

BRCA1_MOUSE
θ value	2.36792 (rank : 198)	NC score	0.172023 (rank : 101)
Query Neighborhood Hits	353	Target Neighborhood Hits	436	Shared Neighborhood Hits	149
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRE1A_HUMAN
θ value	2.36792 (rank : 199)	NC score	0.057530 (rank : 319)
Query Neighborhood Hits	353	Target Neighborhood Hits	1071	Shared Neighborhood Hits	115
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	2.36792 (rank : 200)	NC score	0.057274 (rank : 320)
Query Neighborhood Hits	353	Target Neighborhood Hits	1025	Shared Neighborhood Hits	110
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

EP300_HUMAN
θ value	2.36792 (rank : 201)	NC score	0.048220 (rank : 343)
Query Neighborhood Hits	353	Target Neighborhood Hits	821	Shared Neighborhood Hits	68
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

HXA3_HUMAN
θ value	2.36792 (rank : 202)	NC score	0.006467 (rank : 451)
Query Neighborhood Hits	353	Target Neighborhood Hits	535	Shared Neighborhood Hits	31
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

MLL3_HUMAN
θ value	2.36792 (rank : 203)	NC score	0.078181 (rank : 243)
Query Neighborhood Hits	353	Target Neighborhood Hits	1644	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RGS3_MOUSE
θ value	2.36792 (rank : 204)	NC score	0.050131 (rank : 337)
Query Neighborhood Hits	353	Target Neighborhood Hits	1621	Shared Neighborhood Hits	122
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RN139_MOUSE
θ value	2.36792 (rank : 205)	NC score	0.123038 (rank : 168)
Query Neighborhood Hits	353	Target Neighborhood Hits	131	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RNF41_HUMAN
θ value	2.36792 (rank : 206)	NC score	0.187057 (rank : 83)
Query Neighborhood Hits	353	Target Neighborhood Hits	226	Shared Neighborhood Hits	133
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	2.36792 (rank : 207)	NC score	0.187201 (rank : 82)
Query Neighborhood Hits	353	Target Neighborhood Hits	224	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TOPRS_HUMAN
θ value	2.36792 (rank : 208)	NC score	0.149255 (rank : 141)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	2.36792 (rank : 209)	NC score	0.152939 (rank : 136)
Query Neighborhood Hits	353	Target Neighborhood Hits	263	Shared Neighborhood Hits	131
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF6_HUMAN
θ value	2.36792 (rank : 210)	NC score	0.137883 (rank : 150)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	2.36792 (rank : 211)	NC score	0.137420 (rank : 151)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	124
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI47_HUMAN
θ value	2.36792 (rank : 212)	NC score	0.180208 (rank : 90)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	140
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
θ value	2.36792 (rank : 213)	NC score	0.181445 (rank : 87)
Query Neighborhood Hits	353	Target Neighborhood Hits	295	Shared Neighborhood Hits	139
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI73_HUMAN
θ value	2.36792 (rank : 214)	NC score	0.180923 (rank : 89)
Query Neighborhood Hits	353	Target Neighborhood Hits	258	Shared Neighborhood Hits	147
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	2.36792 (rank : 215)	NC score	0.177205 (rank : 94)
Query Neighborhood Hits	353	Target Neighborhood Hits	249	Shared Neighborhood Hits	138
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

ATX2_HUMAN
θ value	3.0926 (rank : 216)	NC score	0.031116 (rank : 373)
Query Neighborhood Hits	353	Target Neighborhood Hits	375	Shared Neighborhood Hits	36
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

BAT2_HUMAN
θ value	3.0926 (rank : 217)	NC score	0.049915 (rank : 339)
Query Neighborhood Hits	353	Target Neighborhood Hits	931	Shared Neighborhood Hits	84
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BFAR_MOUSE
θ value	3.0926 (rank : 218)	NC score	0.208817 (rank : 58)
Query Neighborhood Hits	353	Target Neighborhood Hits	232	Shared Neighborhood Hits	137
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

CBP_HUMAN
θ value	3.0926 (rank : 219)	NC score	0.058035 (rank : 317)
Query Neighborhood Hits	353	Target Neighborhood Hits	941	Shared Neighborhood Hits	80
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

HAIR_HUMAN
θ value	3.0926 (rank : 220)	NC score	0.017556 (rank : 410)
Query Neighborhood Hits	353	Target Neighborhood Hits	172	Shared Neighborhood Hits	24
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

IASPP_HUMAN
θ value	3.0926 (rank : 221)	NC score	0.018515 (rank : 407)
Query Neighborhood Hits	353	Target Neighborhood Hits	688	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LNX2_HUMAN
θ value	3.0926 (rank : 222)	NC score	0.105168 (rank : 189)
Query Neighborhood Hits	353	Target Neighborhood Hits	389	Shared Neighborhood Hits	136
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

NFAC4_HUMAN
θ value	3.0926 (rank : 223)	NC score	0.023823 (rank : 388)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	16
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PJA1_HUMAN
θ value	3.0926 (rank : 224)	NC score	0.157247 (rank : 129)
Query Neighborhood Hits	353	Target Neighborhood Hits	159	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	3.0926 (rank : 225)	NC score	0.156561 (rank : 131)
Query Neighborhood Hits	353	Target Neighborhood Hits	145	Shared Neighborhood Hits	77
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PS1C2_MOUSE
θ value	3.0926 (rank : 226)	NC score	0.066919 (rank : 281)
Query Neighborhood Hits	353	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

RAG1_MOUSE
θ value	3.0926 (rank : 227)	NC score	0.129838 (rank : 164)
Query Neighborhood Hits	353	Target Neighborhood Hits	189	Shared Neighborhood Hits	112
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RERE_MOUSE
θ value	3.0926 (rank : 228)	NC score	0.043717 (rank : 352)
Query Neighborhood Hits	353	Target Neighborhood Hits	785	Shared Neighborhood Hits	59
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RNF37_HUMAN
θ value	3.0926 (rank : 229)	NC score	0.102640 (rank : 199)
Query Neighborhood Hits	353	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

T240L_HUMAN
θ value	3.0926 (rank : 230)	NC score	0.022510 (rank : 394)
Query Neighborhood Hits	353	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

T240L_MOUSE
θ value	3.0926 (rank : 231)	NC score	0.024333 (rank : 387)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	19
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

TRI50_MOUSE
θ value	3.0926 (rank : 232)	NC score	0.171541 (rank : 103)
Query Neighborhood Hits	353	Target Neighborhood Hits	326	Shared Neighborhood Hits	159
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ZO1_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.020619 (rank : 399)
Query Neighborhood Hits	353	Target Neighborhood Hits	474	Shared Neighborhood Hits	42
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CN032_HUMAN
θ value	4.03905 (rank : 234)	NC score	0.049766 (rank : 340)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

ENAH_MOUSE
θ value	4.03905 (rank : 235)	NC score	0.052538 (rank : 330)
Query Neighborhood Hits	353	Target Neighborhood Hits	919	Shared Neighborhood Hits	70
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GLIS1_MOUSE
θ value	4.03905 (rank : 236)	NC score	0.002692 (rank : 459)
Query Neighborhood Hits	353	Target Neighborhood Hits	751	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

ITSN2_HUMAN
θ value	4.03905 (rank : 237)	NC score	0.009753 (rank : 439)
Query Neighborhood Hits	353	Target Neighborhood Hits	1173	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MKRN1_HUMAN
θ value	4.03905 (rank : 238)	NC score	0.051517 (rank : 333)
Query Neighborhood Hits	353	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

RN122_HUMAN
θ value	4.03905 (rank : 239)	NC score	0.154928 (rank : 135)
Query Neighborhood Hits	353	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

SRMS_MOUSE
θ value	4.03905 (rank : 240)	NC score	-0.002118 (rank : 468)
Query Neighborhood Hits	353	Target Neighborhood Hits	964	Shared Neighborhood Hits	18
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SRTD3_MOUSE
θ value	4.03905 (rank : 241)	NC score	0.019666 (rank : 403)
Query Neighborhood Hits	353	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

TRAF2_MOUSE
θ value	4.03905 (rank : 242)	NC score	0.078137 (rank : 244)
Query Neighborhood Hits	353	Target Neighborhood Hits	394	Shared Neighborhood Hits	101
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF4_MOUSE
θ value	4.03905 (rank : 243)	NC score	0.087844 (rank : 222)
Query Neighborhood Hits	353	Target Neighborhood Hits	338	Shared Neighborhood Hits	94
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRI27_HUMAN
θ value	4.03905 (rank : 244)	NC score	0.142933 (rank : 147)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	143
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRIM4_HUMAN
θ value	4.03905 (rank : 245)	NC score	0.158069 (rank : 123)
Query Neighborhood Hits	353	Target Neighborhood Hits	321	Shared Neighborhood Hits	145
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TTK_MOUSE
θ value	4.03905 (rank : 246)	NC score	-0.001067 (rank : 466)
Query Neighborhood Hits	353	Target Neighborhood Hits	803	Shared Neighborhood Hits	9
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

V1BR_HUMAN
θ value	4.03905 (rank : 247)	NC score	-0.002801 (rank : 469)
Query Neighborhood Hits	353	Target Neighborhood Hits	895	Shared Neighborhood Hits	3
SwissProt Accessions	P47901, Q5TZ00	Gene names	AVPR1B, AVPR3, VPR3
Domain Architecture
Description	Vasopressin V1b receptor (V1bR) (AVPR V1b) (Vasopressin V3 receptor) (AVPR V3) (Antidiuretic hormone receptor 1b).

YLPM1_MOUSE
θ value	4.03905 (rank : 248)	NC score	0.051425 (rank : 334)
Query Neighborhood Hits	353	Target Neighborhood Hits	505	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZFP92_MOUSE
θ value	4.03905 (rank : 249)	NC score	-0.002076 (rank : 467)
Query Neighborhood Hits	353	Target Neighborhood Hits	731	Shared Neighborhood Hits	13
SwissProt Accessions	Q62396	Gene names	Zfp92
Domain Architecture
Description	Zinc finger protein 92 (Zfp-92).

ZN363_HUMAN
θ value	4.03905 (rank : 250)	NC score	0.083634 (rank : 229)
Query Neighborhood Hits	353	Target Neighborhood Hits	162	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	4.03905 (rank : 251)	NC score	0.103165 (rank : 197)
Query Neighborhood Hits	353	Target Neighborhood Hits	134	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN668_MOUSE
θ value	4.03905 (rank : 252)	NC score	-0.000808 (rank : 464)
Query Neighborhood Hits	353	Target Neighborhood Hits	763	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K2R5, Q3TEM2, Q3U7Y5, Q8C8B7	Gene names	Znf668, Zfp668
Domain Architecture	No domain graphic available
Description	Zinc finger protein 668.

ZYX_HUMAN
θ value	4.03905 (rank : 253)	NC score	0.013740 (rank : 419)
Query Neighborhood Hits	353	Target Neighborhood Hits	387	Shared Neighborhood Hits	30
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

BCL9_MOUSE
θ value	5.27518 (rank : 254)	NC score	0.053735 (rank : 326)
Query Neighborhood Hits	353	Target Neighborhood Hits	770	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BFAR_HUMAN
θ value	5.27518 (rank : 255)	NC score	0.200509 (rank : 65)
Query Neighborhood Hits	353	Target Neighborhood Hits	222	Shared Neighborhood Hits	133
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BRCA1_HUMAN
θ value	5.27518 (rank : 256)	NC score	0.161741 (rank : 116)
Query Neighborhood Hits	353	Target Neighborhood Hits	381	Shared Neighborhood Hits	140
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

CJ047_HUMAN
θ value	5.27518 (rank : 257)	NC score	0.019857 (rank : 401)
Query Neighborhood Hits	353	Target Neighborhood Hits	164	Shared Neighborhood Hits	18
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

H2B2C_HUMAN
θ value	5.27518 (rank : 258)	NC score	0.009776 (rank : 438)
Query Neighborhood Hits	353	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DN03	Gene names	HIST2H2BC
Domain Architecture	No domain graphic available
Description	Histone H2B type 2-C (H2.t) (H2B/t).

IASPP_MOUSE
θ value	5.27518 (rank : 259)	NC score	0.026660 (rank : 379)
Query Neighborhood Hits	353	Target Neighborhood Hits	1024	Shared Neighborhood Hits	72
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IRS2_HUMAN
θ value	5.27518 (rank : 260)	NC score	0.031618 (rank : 371)
Query Neighborhood Hits	353	Target Neighborhood Hits	262	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

LNX2_MOUSE
θ value	5.27518 (rank : 261)	NC score	0.102263 (rank : 201)
Query Neighborhood Hits	353	Target Neighborhood Hits	407	Shared Neighborhood Hits	141
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LRSM1_MOUSE
θ value	5.27518 (rank : 262)	NC score	0.071195 (rank : 265)
Query Neighborhood Hits	353	Target Neighborhood Hits	874	Shared Neighborhood Hits	101
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MARH4_HUMAN
θ value	5.27518 (rank : 263)	NC score	0.014714 (rank : 415)
Query Neighborhood Hits	353	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2E8, Q86WR8	Gene names	MARCH4, KIAA1399, RNF174
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 4 (Membrane-associated RING-CH protein IV) (MARCH-IV) (RING finger protein 174).

MIB1_HUMAN
θ value	5.27518 (rank : 264)	NC score	0.060504 (rank : 308)
Query Neighborhood Hits	353	Target Neighborhood Hits	470	Shared Neighborhood Hits	96
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MKRN3_HUMAN
θ value	5.27518 (rank : 265)	NC score	0.059300 (rank : 313)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	70
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MLL3_MOUSE
θ value	5.27518 (rank : 266)	NC score	0.064884 (rank : 289)
Query Neighborhood Hits	353	Target Neighborhood Hits	1399	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NFIB_MOUSE
θ value	5.27518 (rank : 267)	NC score	0.009267 (rank : 440)
Query Neighborhood Hits	353	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PO121_HUMAN
θ value	5.27518 (rank : 268)	NC score	0.025826 (rank : 381)
Query Neighborhood Hits	353	Target Neighborhood Hits	344	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RIN3_HUMAN
θ value	5.27518 (rank : 269)	NC score	0.035273 (rank : 362)
Query Neighborhood Hits	353	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ROBO4_MOUSE
θ value	5.27518 (rank : 270)	NC score	0.023519 (rank : 391)
Query Neighborhood Hits	353	Target Neighborhood Hits	358	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SLIK4_MOUSE
θ value	5.27518 (rank : 271)	NC score	0.002505 (rank : 460)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	Q810B8, Q8BL56, Q8BWB0, Q8BYG4, Q8C056	Gene names	Slitrk4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

SOX13_HUMAN
θ value	5.27518 (rank : 272)	NC score	0.023250 (rank : 392)
Query Neighborhood Hits	353	Target Neighborhood Hits	464	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

STAP2_HUMAN
θ value	5.27518 (rank : 273)	NC score	0.019508 (rank : 404)
Query Neighborhood Hits	353	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGK3, Q9NXI2	Gene names	STAP2, BKS
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate).

STAP2_MOUSE
θ value	5.27518 (rank : 274)	NC score	0.018346 (rank : 408)
Query Neighborhood Hits	353	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0L1, Q8BWS2	Gene names	Stap2
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2).

SUHW4_MOUSE
θ value	5.27518 (rank : 275)	NC score	0.002352 (rank : 461)
Query Neighborhood Hits	353	Target Neighborhood Hits	737	Shared Neighborhood Hits	19
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TRAF7_HUMAN
θ value	5.27518 (rank : 276)	NC score	0.070367 (rank : 268)
Query Neighborhood Hits	353	Target Neighborhood Hits	482	Shared Neighborhood Hits	126
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	5.27518 (rank : 277)	NC score	0.070301 (rank : 270)
Query Neighborhood Hits	353	Target Neighborhood Hits	470	Shared Neighborhood Hits	123
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI27_MOUSE
θ value	5.27518 (rank : 278)	NC score	0.139442 (rank : 148)
Query Neighborhood Hits	353	Target Neighborhood Hits	261	Shared Neighborhood Hits	136
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRIM5_HUMAN
θ value	5.27518 (rank : 279)	NC score	0.156120 (rank : 132)
Query Neighborhood Hits	353	Target Neighborhood Hits	424	Shared Neighborhood Hits	153
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM7_MOUSE
θ value	5.27518 (rank : 280)	NC score	0.148796 (rank : 142)
Query Neighborhood Hits	353	Target Neighborhood Hits	358	Shared Neighborhood Hits	126
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TXND2_HUMAN
θ value	5.27518 (rank : 281)	NC score	0.034760 (rank : 363)
Query Neighborhood Hits	353	Target Neighborhood Hits	793	Shared Neighborhood Hits	59
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

AFF4_MOUSE
θ value	6.88961 (rank : 282)	NC score	0.030381 (rank : 376)
Query Neighborhood Hits	353	Target Neighborhood Hits	581	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

BAG4_HUMAN
θ value	6.88961 (rank : 283)	NC score	0.016815 (rank : 412)
Query Neighborhood Hits	353	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

BCL9_HUMAN
θ value	6.88961 (rank : 284)	NC score	0.061640 (rank : 303)
Query Neighborhood Hits	353	Target Neighborhood Hits	1008	Shared Neighborhood Hits	94
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CUTL2_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.011879 (rank : 430)
Query Neighborhood Hits	353	Target Neighborhood Hits	906	Shared Neighborhood Hits	42
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

E2AK3_HUMAN
θ value	6.88961 (rank : 286)	NC score	-0.000417 (rank : 463)
Query Neighborhood Hits	353	Target Neighborhood Hits	859	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

EVPL_MOUSE
θ value	6.88961 (rank : 287)	NC score	0.013262 (rank : 423)
Query Neighborhood Hits	353	Target Neighborhood Hits	952	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FA48A_HUMAN
θ value	6.88961 (rank : 288)	NC score	0.012591 (rank : 427)
Query Neighborhood Hits	353	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

GCX1_HUMAN
θ value	6.88961 (rank : 289)	NC score	0.013335 (rank : 422)
Query Neighborhood Hits	353	Target Neighborhood Hits	132	Shared Neighborhood Hits	13
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

K1802_HUMAN
θ value	6.88961 (rank : 290)	NC score	0.034427 (rank : 364)
Query Neighborhood Hits	353	Target Neighborhood Hits	1378	Shared Neighborhood Hits	94
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNH2_MOUSE
θ value	6.88961 (rank : 291)	NC score	0.010355 (rank : 435)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

MKRN1_MOUSE
θ value	6.88961 (rank : 292)	NC score	0.048340 (rank : 342)
Query Neighborhood Hits	353	Target Neighborhood Hits	141	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

NCOA1_MOUSE
θ value	6.88961 (rank : 293)	NC score	0.008106 (rank : 446)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	18
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA6_MOUSE
θ value	6.88961 (rank : 294)	NC score	0.057106 (rank : 321)
Query Neighborhood Hits	353	Target Neighborhood Hits	1076	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PARP4_HUMAN
θ value	6.88961 (rank : 295)	NC score	0.014220 (rank : 417)
Query Neighborhood Hits	353	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

PCLO_MOUSE
θ value	6.88961 (rank : 296)	NC score	0.037987 (rank : 358)
Query Neighborhood Hits	353	Target Neighborhood Hits	2275	Shared Neighborhood Hits	126
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PLS4_MOUSE
θ value	6.88961 (rank : 297)	NC score	0.008400 (rank : 444)
Query Neighborhood Hits	353	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	P58196, Q3TMI2, Q8BH62	Gene names	Plscr4
Domain Architecture	No domain graphic available
Description	Phospholipid scramblase 4 (PL scramblase 4) (Ca(2+)-dependent phospholipid scramblase 4).

SGIP1_MOUSE
θ value	6.88961 (rank : 298)	NC score	0.061790 (rank : 302)
Query Neighborhood Hits	353	Target Neighborhood Hits	180	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYNJ2_MOUSE
θ value	6.88961 (rank : 299)	NC score	0.008537 (rank : 443)
Query Neighborhood Hits	353	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

TF3C2_HUMAN
θ value	6.88961 (rank : 300)	NC score	0.032944 (rank : 367)
Query Neighborhood Hits	353	Target Neighborhood Hits	168	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TIF1B_HUMAN
θ value	6.88961 (rank : 301)	NC score	0.087964 (rank : 221)
Query Neighborhood Hits	353	Target Neighborhood Hits	312	Shared Neighborhood Hits	83
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	6.88961 (rank : 302)	NC score	0.089008 (rank : 219)
Query Neighborhood Hits	353	Target Neighborhood Hits	276	Shared Neighborhood Hits	75
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TNC6B_HUMAN
θ value	6.88961 (rank : 303)	NC score	0.038542 (rank : 357)
Query Neighborhood Hits	353	Target Neighborhood Hits	256	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

TRAF3_MOUSE
θ value	6.88961 (rank : 304)	NC score	0.079652 (rank : 238)
Query Neighborhood Hits	353	Target Neighborhood Hits	476	Shared Neighborhood Hits	111
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRI31_HUMAN
θ value	6.88961 (rank : 305)	NC score	0.179754 (rank : 91)
Query Neighborhood Hits	353	Target Neighborhood Hits	299	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

AAKG2_MOUSE
θ value	8.99809 (rank : 306)	NC score	0.005771 (rank : 453)
Query Neighborhood Hits	353	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

ABI3_HUMAN
θ value	8.99809 (rank : 307)	NC score	0.011047 (rank : 433)
Query Neighborhood Hits	353	Target Neighborhood Hits	227	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

APXL_HUMAN
θ value	8.99809 (rank : 308)	NC score	0.024978 (rank : 384)
Query Neighborhood Hits	353	Target Neighborhood Hits	553	Shared Neighborhood Hits	43
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ATP7A_MOUSE
θ value	8.99809 (rank : 309)	NC score	0.003627 (rank : 457)
Query Neighborhood Hits	353	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q64430, O35101, P97422, Q64431	Gene names	Atp7a, Mnk
Domain Architecture
Description	Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein homolog).

B4GN4_HUMAN
θ value	8.99809 (rank : 310)	NC score	0.009947 (rank : 436)
Query Neighborhood Hits	353	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BAG3_HUMAN
θ value	8.99809 (rank : 311)	NC score	0.025895 (rank : 380)
Query Neighborhood Hits	353	Target Neighborhood Hits	314	Shared Neighborhood Hits	46
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BRAP_HUMAN
θ value	8.99809 (rank : 312)	NC score	0.098093 (rank : 205)
Query Neighborhood Hits	353	Target Neighborhood Hits	560	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

CEL_HUMAN
θ value	8.99809 (rank : 313)	NC score	0.036611 (rank : 360)
Query Neighborhood Hits	353	Target Neighborhood Hits	896	Shared Neighborhood Hits	78
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CIC_HUMAN
θ value	8.99809 (rank : 314)	NC score	0.032793 (rank : 369)
Query Neighborhood Hits	353	Target Neighborhood Hits	992	Shared Neighborhood Hits	87
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DRAP1_MOUSE
θ value	8.99809 (rank : 315)	NC score	0.019727 (rank : 402)
Query Neighborhood Hits	353	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

FMNL_HUMAN
θ value	8.99809 (rank : 316)	NC score	0.020539 (rank : 400)
Query Neighborhood Hits	353	Target Neighborhood Hits	529	Shared Neighborhood Hits	47
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GA2L1_MOUSE
θ value	8.99809 (rank : 317)	NC score	0.012795 (rank : 426)
Query Neighborhood Hits	353	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GAB1_HUMAN
θ value	8.99809 (rank : 318)	NC score	0.021903 (rank : 395)
Query Neighborhood Hits	353	Target Neighborhood Hits	279	Shared Neighborhood Hits	36
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GFC1_HUMAN
θ value	8.99809 (rank : 319)	NC score	0.013716 (rank : 420)
Query Neighborhood Hits	353	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

GO45_MOUSE
θ value	8.99809 (rank : 320)	NC score	0.013490 (rank : 421)
Query Neighborhood Hits	353	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2X8, Q3TJC4, Q8C0U6, Q9DAV7	Gene names	Blzf1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1).

HXA3_MOUSE
θ value	8.99809 (rank : 321)	NC score	0.005596 (rank : 454)
Query Neighborhood Hits	353	Target Neighborhood Hits	558	Shared Neighborhood Hits	33
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IRS1_HUMAN
θ value	8.99809 (rank : 322)	NC score	0.012053 (rank : 429)
Query Neighborhood Hits	353	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IWS1_MOUSE
θ value	8.99809 (rank : 323)	NC score	0.023205 (rank : 393)
Query Neighborhood Hits	353	Target Neighborhood Hits	1258	Shared Neighborhood Hits	75
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K0310_HUMAN
θ value	8.99809 (rank : 324)	NC score	0.024924 (rank : 385)
Query Neighborhood Hits	353	Target Neighborhood Hits	420	Shared Neighborhood Hits	43
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K0494_MOUSE
θ value	8.99809 (rank : 325)	NC score	0.013035 (rank : 425)
Query Neighborhood Hits	353	Target Neighborhood Hits	241	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

LAMA3_MOUSE
θ value	8.99809 (rank : 326)	NC score	0.006274 (rank : 452)
Query Neighborhood Hits	353	Target Neighborhood Hits	859	Shared Neighborhood Hits	16
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LUM_HUMAN
θ value	8.99809 (rank : 327)	NC score	-0.000973 (rank : 465)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	P51884, Q96QM7	Gene names	LUM, LDC
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

MKRN4_HUMAN
θ value	8.99809 (rank : 328)	NC score	0.053862 (rank : 325)
Query Neighborhood Hits	353	Target Neighborhood Hits	147	Shared Neighborhood Hits	78
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MNT_MOUSE
θ value	8.99809 (rank : 329)	NC score	0.033222 (rank : 365)
Query Neighborhood Hits	353	Target Neighborhood Hits	432	Shared Neighborhood Hits	46
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NAGS_HUMAN
θ value	8.99809 (rank : 330)	NC score	0.009156 (rank : 441)
Query Neighborhood Hits	353	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N159, Q8IWR4	Gene names	NAGS
Domain Architecture	No domain graphic available
Description	N-acetylglutamate synthase, mitochondrial precursor (EC 2.3.1.1) (Amino-acid acetyltransferase) [Contains: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form].

NFAC1_HUMAN
θ value	8.99809 (rank : 331)	NC score	0.023735 (rank : 389)
Query Neighborhood Hits	353	Target Neighborhood Hits	312	Shared Neighborhood Hits	37
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PO6F2_HUMAN
θ value	8.99809 (rank : 332)	NC score	0.008336 (rank : 445)
Query Neighborhood Hits	353	Target Neighborhood Hits	618	Shared Neighborhood Hits	39
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PRG4_HUMAN
θ value	8.99809 (rank : 333)	NC score	0.046037 (rank : 347)
Query Neighborhood Hits	353	Target Neighborhood Hits	764	Shared Neighborhood Hits	60
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PTN23_MOUSE
θ value	8.99809 (rank : 334)	NC score	0.013081 (rank : 424)
Query Neighborhood Hits	353	Target Neighborhood Hits	726	Shared Neighborhood Hits	60
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RAG1_HUMAN
θ value	8.99809 (rank : 335)	NC score	0.117715 (rank : 173)
Query Neighborhood Hits	353	Target Neighborhood Hits	203	Shared Neighborhood Hits	111
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RFWD2_HUMAN
θ value	8.99809 (rank : 336)	NC score	0.106836 (rank : 187)
Query Neighborhood Hits	353	Target Neighborhood Hits	518	Shared Neighborhood Hits	151
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	8.99809 (rank : 337)	NC score	0.108170 (rank : 185)
Query Neighborhood Hits	353	Target Neighborhood Hits	535	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RNC_HUMAN
θ value	8.99809 (rank : 338)	NC score	0.016783 (rank : 413)
Query Neighborhood Hits	353	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

RNF4_HUMAN
θ value	8.99809 (rank : 339)	NC score	0.186490 (rank : 85)
Query Neighborhood Hits	353	Target Neighborhood Hits	212	Shared Neighborhood Hits	142
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	8.99809 (rank : 340)	NC score	0.185379 (rank : 86)
Query Neighborhood Hits	353	Target Neighborhood Hits	212	Shared Neighborhood Hits	142
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TENS4_HUMAN
θ value	8.99809 (rank : 341)	NC score	0.016905 (rank : 411)
Query Neighborhood Hits	353	Target Neighborhood Hits	214	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TENS4_MOUSE
θ value	8.99809 (rank : 342)	NC score	0.021885 (rank : 396)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

TPO_MOUSE
θ value	8.99809 (rank : 343)	NC score	0.030388 (rank : 375)
Query Neighborhood Hits	353	Target Neighborhood Hits	258	Shared Neighborhood Hits	39
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TRAF4_HUMAN
θ value	8.99809 (rank : 344)	NC score	0.090301 (rank : 217)
Query Neighborhood Hits	353	Target Neighborhood Hits	373	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRI17_MOUSE
θ value	8.99809 (rank : 345)	NC score	0.137897 (rank : 149)
Query Neighborhood Hits	353	Target Neighborhood Hits	620	Shared Neighborhood Hits	145
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRIM1_HUMAN
θ value	8.99809 (rank : 346)	NC score	0.110227 (rank : 182)
Query Neighborhood Hits	353	Target Neighborhood Hits	345	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	8.99809 (rank : 347)	NC score	0.110368 (rank : 180)
Query Neighborhood Hits	353	Target Neighborhood Hits	361	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM7_HUMAN
θ value	8.99809 (rank : 348)	NC score	0.143902 (rank : 145)
Query Neighborhood Hits	353	Target Neighborhood Hits	336	Shared Neighborhood Hits	128
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

V1BR_MOUSE
θ value	8.99809 (rank : 349)	NC score	-0.004187 (rank : 470)
Query Neighborhood Hits	353	Target Neighborhood Hits	895	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU02	Gene names	Avpr1b, V1br
Domain Architecture
Description	Vasopressin V1b receptor (V1bR) (AVPR V1b) (Vasopressin V3 receptor) (AVPR V3) (Antidiuretic hormone receptor 1b).

VINEX_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.012084 (rank : 428)
Query Neighborhood Hits	353	Target Neighborhood Hits	270	Shared Neighborhood Hits	13
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

WNK4_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.003425 (rank : 458)
Query Neighborhood Hits	353	Target Neighborhood Hits	961	Shared Neighborhood Hits	33
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZFHX2_HUMAN
θ value	8.99809 (rank : 352)	NC score	0.016570 (rank : 414)
Query Neighborhood Hits	353	Target Neighborhood Hits	1178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ZN179_HUMAN
θ value	8.99809 (rank : 353)	NC score	0.158035 (rank : 124)
Query Neighborhood Hits	353	Target Neighborhood Hits	178	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

BRAP_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.097856 (rank : 206)
Query Neighborhood Hits	353	Target Neighborhood Hits	409	Shared Neighborhood Hits	78
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BSPRY_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.077845 (rank : 245)
Query Neighborhood Hits	353	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.084136 (rank : 228)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.064253 (rank : 294)
Query Neighborhood Hits	353	Target Neighborhood Hits	322	Shared Neighborhood Hits	40
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.066121 (rank : 284)
Query Neighborhood Hits	353	Target Neighborhood Hits	252	Shared Neighborhood Hits	41
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.063301 (rank : 297)
Query Neighborhood Hits	353	Target Neighborhood Hits	185	Shared Neighborhood Hits	40
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.065317 (rank : 287)
Query Neighborhood Hits	353	Target Neighborhood Hits	191	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.062356 (rank : 299)
Query Neighborhood Hits	353	Target Neighborhood Hits	195	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.064470 (rank : 293)
Query Neighborhood Hits	353	Target Neighborhood Hits	229	Shared Neighborhood Hits	40
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.065627 (rank : 286)
Query Neighborhood Hits	353	Target Neighborhood Hits	233	Shared Neighborhood Hits	43
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.062981 (rank : 298)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.061333 (rank : 306)
Query Neighborhood Hits	353	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.064732 (rank : 292)
Query Neighborhood Hits	353	Target Neighborhood Hits	125	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CGRF1_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.057891 (rank : 318)
Query Neighborhood Hits	353	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.053385 (rank : 327)
Query Neighborhood Hits	353	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CM007_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.109526 (rank : 183)
Query Neighborhood Hits	353	Target Neighborhood Hits	422	Shared Neighborhood Hits	113
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.120030 (rank : 170)
Query Neighborhood Hits	353	Target Neighborhood Hits	416	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DTX3L_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.077837 (rank : 246)
Query Neighborhood Hits	353	Target Neighborhood Hits	187	Shared Neighborhood Hits	96
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.095234 (rank : 209)
Query Neighborhood Hits	353	Target Neighborhood Hits	198	Shared Neighborhood Hits	122
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.093559 (rank : 211)
Query Neighborhood Hits	353	Target Neighborhood Hits	202	Shared Neighborhood Hits	123
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

ERMAP_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.075653 (rank : 250)
Query Neighborhood Hits	353	Target Neighborhood Hits	155	Shared Neighborhood Hits	40
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.069243 (rank : 275)
Query Neighborhood Hits	353	Target Neighborhood Hits	231	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

LRSM1_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.051697 (rank : 332)
Query Neighborhood Hits	353	Target Neighborhood Hits	1078	Shared Neighborhood Hits	104
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MEFV_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.091855 (rank : 214)
Query Neighborhood Hits	353	Target Neighborhood Hits	431	Shared Neighborhood Hits	74
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.091993 (rank : 213)
Query Neighborhood Hits	353	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MKRN2_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.050638 (rank : 336)
Query Neighborhood Hits	353	Target Neighborhood Hits	130	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

NCOA6_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.051250 (rank : 335)
Query Neighborhood Hits	353	Target Neighborhood Hits	1202	Shared Neighborhood Hits	91
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PCGF2_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.076472 (rank : 249)
Query Neighborhood Hits	353	Target Neighborhood Hits	222	Shared Neighborhood Hits	109
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.076542 (rank : 248)
Query Neighborhood Hits	353	Target Neighborhood Hits	213	Shared Neighborhood Hits	109
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.070324 (rank : 269)
Query Neighborhood Hits	353	Target Neighborhood Hits	161	Shared Neighborhood Hits	104
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.070059 (rank : 272)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	102
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF6_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.072220 (rank : 259)
Query Neighborhood Hits	353	Target Neighborhood Hits	178	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.070790 (rank : 267)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	90
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PRRT3_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.053268 (rank : 328)
Query Neighborhood Hits	353	Target Neighborhood Hits	998	Shared Neighborhood Hits	98
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

R113A_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.088329 (rank : 220)
Query Neighborhood Hits	353	Target Neighborhood Hits	177	Shared Neighborhood Hits	97
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.079823 (rank : 236)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAD18_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.101944 (rank : 202)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.104382 (rank : 193)
Query Neighborhood Hits	353	Target Neighborhood Hits	230	Shared Neighborhood Hits	106
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RBBP6_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.089345 (rank : 218)
Query Neighborhood Hits	353	Target Neighborhood Hits	1135	Shared Neighborhood Hits	144
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.100495 (rank : 203)
Query Neighborhood Hits	353	Target Neighborhood Hits	1014	Shared Neighborhood Hits	147
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBX2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.055287 (rank : 323)
Query Neighborhood Hits	353	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.055425 (rank : 322)
Query Neighborhood Hits	353	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RFPL1_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.076698 (rank : 247)
Query Neighborhood Hits	353	Target Neighborhood Hits	119	Shared Neighborhood Hits	61
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.079148 (rank : 239)
Query Neighborhood Hits	353	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.079737 (rank : 237)
Query Neighborhood Hits	353	Target Neighborhood Hits	134	Shared Neighborhood Hits	72
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RN139_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.104270 (rank : 194)
Query Neighborhood Hits	353	Target Neighborhood Hits	130	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN146_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.118256 (rank : 172)
Query Neighborhood Hits	353	Target Neighborhood Hits	162	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.117391 (rank : 174)
Query Neighborhood Hits	353	Target Neighborhood Hits	161	Shared Neighborhood Hits	114
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN152_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.074549 (rank : 253)
Query Neighborhood Hits	353	Target Neighborhood Hits	107	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.078417 (rank : 242)
Query Neighborhood Hits	353	Target Neighborhood Hits	109	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN175_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.063982 (rank : 295)
Query Neighborhood Hits	353	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

RN183_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.090994 (rank : 215)
Query Neighborhood Hits	353	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.082985 (rank : 230)
Query Neighborhood Hits	353	Target Neighborhood Hits	119	Shared Neighborhood Hits	74
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF11_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.103860 (rank : 195)
Query Neighborhood Hits	353	Target Neighborhood Hits	81	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.103402 (rank : 196)
Query Neighborhood Hits	353	Target Neighborhood Hits	81	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RNF12_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.102551 (rank : 200)
Query Neighborhood Hits	353	Target Neighborhood Hits	173	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF12_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.110339 (rank : 181)
Query Neighborhood Hits	353	Target Neighborhood Hits	159	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF32_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.094860 (rank : 210)
Query Neighborhood Hits	353	Target Neighborhood Hits	133	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.084254 (rank : 227)
Query Neighborhood Hits	353	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF38_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.105142 (rank : 190)
Query Neighborhood Hits	353	Target Neighborhood Hits	155	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF38_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.102671 (rank : 198)
Query Neighborhood Hits	353	Target Neighborhood Hits	153	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF39_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.108372 (rank : 184)
Query Neighborhood Hits	353	Target Neighborhood Hits	200	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF6_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.095977 (rank : 208)
Query Neighborhood Hits	353	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

SPRY4_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.059490 (rank : 312)
Query Neighborhood Hits	353	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.061169 (rank : 307)
Query Neighborhood Hits	353	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TIF1A_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.052406 (rank : 331)
Query Neighborhood Hits	353	Target Neighborhood Hits	327	Shared Neighborhood Hits	77
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1G_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.069388 (rank : 274)
Query Neighborhood Hits	353	Target Neighborhood Hits	410	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.070831 (rank : 266)
Query Neighborhood Hits	353	Target Neighborhood Hits	498	Shared Neighborhood Hits	101
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRAF2_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.064736 (rank : 291)
Query Neighborhood Hits	353	Target Neighborhood Hits	402	Shared Neighborhood Hits	94
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF3_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.061904 (rank : 301)
Query Neighborhood Hits	353	Target Neighborhood Hits	463	Shared Neighborhood Hits	100
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.065002 (rank : 288)
Query Neighborhood Hits	353	Target Neighborhood Hits	396	Shared Neighborhood Hits	94
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.073924 (rank : 255)
Query Neighborhood Hits	353	Target Neighborhood Hits	355	Shared Neighborhood Hits	100
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI12_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.152103 (rank : 137)
Query Neighborhood Hits	353	Target Neighborhood Hits	387	Shared Neighborhood Hits	142
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI14_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.084447 (rank : 226)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.082980 (rank : 231)
Query Neighborhood Hits	353	Target Neighborhood Hits	137	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI16_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.078578 (rank : 240)
Query Neighborhood Hits	353	Target Neighborhood Hits	231	Shared Neighborhood Hits	57
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.085719 (rank : 224)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	57
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI18_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.106517 (rank : 188)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	134
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.107058 (rank : 186)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	136
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI22_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.136228 (rank : 153)
Query Neighborhood Hits	353	Target Neighborhood Hits	396	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI29_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.072633 (rank : 258)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	57
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.074760 (rank : 252)
Query Neighborhood Hits	353	Target Neighborhood Hits	306	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI34_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.124671 (rank : 167)
Query Neighborhood Hits	353	Target Neighborhood Hits	416	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.115965 (rank : 175)
Query Neighborhood Hits	353	Target Neighborhood Hits	332	Shared Neighborhood Hits	110
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI36_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.072018 (rank : 261)
Query Neighborhood Hits	353	Target Neighborhood Hits	282	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.069809 (rank : 273)
Query Neighborhood Hits	353	Target Neighborhood Hits	266	Shared Neighborhood Hits	97
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI38_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.128368 (rank : 166)
Query Neighborhood Hits	353	Target Neighborhood Hits	373	Shared Neighborhood Hits	127
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI41_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.120383 (rank : 169)
Query Neighborhood Hits	353	Target Neighborhood Hits	349	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI42_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.061373 (rank : 305)
Query Neighborhood Hits	353	Target Neighborhood Hits	283	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.059860 (rank : 311)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.067401 (rank : 279)
Query Neighborhood Hits	353	Target Neighborhood Hits	393	Shared Neighborhood Hits	55
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.068294 (rank : 278)
Query Neighborhood Hits	353	Target Neighborhood Hits	327	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI45_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.072725 (rank : 257)
Query Neighborhood Hits	353	Target Neighborhood Hits	155	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.071586 (rank : 263)
Query Neighborhood Hits	353	Target Neighborhood Hits	155	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI46_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.081941 (rank : 232)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.081652 (rank : 233)
Query Neighborhood Hits	353	Target Neighborhood Hits	287	Shared Neighborhood Hits	114
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI48_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.119763 (rank : 171)
Query Neighborhood Hits	353	Target Neighborhood Hits	192	Shared Neighborhood Hits	113
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI49_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.115890 (rank : 176)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI52_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.150866 (rank : 138)
Query Neighborhood Hits	353	Target Neighborhood Hits	213	Shared Neighborhood Hits	126
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI54_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.114591 (rank : 177)
Query Neighborhood Hits	353	Target Neighborhood Hits	209	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.113022 (rank : 178)
Query Neighborhood Hits	353	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.100179 (rank : 204)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI63_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.105052 (rank : 191)
Query Neighborhood Hits	353	Target Neighborhood Hits	298	Shared Neighborhood Hits	105
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.105027 (rank : 192)
Query Neighborhood Hits	353	Target Neighborhood Hits	240	Shared Neighborhood Hits	104
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRIM6_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.133088 (rank : 157)
Query Neighborhood Hits	353	Target Neighborhood Hits	412	Shared Neighborhood Hits	135
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM6_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.133104 (rank : 156)
Query Neighborhood Hits	353	Target Neighborhood Hits	451	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM8_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.130829 (rank : 159)
Query Neighborhood Hits	353	Target Neighborhood Hits	650	Shared Neighborhood Hits	137
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.130307 (rank : 163)
Query Neighborhood Hits	353	Target Neighborhood Hits	674	Shared Neighborhood Hits	139
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM9_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.085781 (rank : 223)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	105
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.085640 (rank : 225)
Query Neighborhood Hits	353	Target Neighborhood Hits	274	Shared Neighborhood Hits	105
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TTC3_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.060297 (rank : 310)
Query Neighborhood Hits	353	Target Neighborhood Hits	664	Shared Neighborhood Hits	75
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

UHRF1_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.065918 (rank : 285)
Query Neighborhood Hits	353	Target Neighborhood Hits	272	Shared Neighborhood Hits	114
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.063897 (rank : 296)
Query Neighborhood Hits	353	Target Neighborhood Hits	278	Shared Neighborhood Hits	116
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.081271 (rank : 234)
Query Neighborhood Hits	353	Target Neighborhood Hits	269	Shared Neighborhood Hits	124
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.078489 (rank : 241)
Query Neighborhood Hits	353	Target Neighborhood Hits	275	Shared Neighborhood Hits	120
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.071213 (rank : 264)
Query Neighborhood Hits	353	Target Neighborhood Hits	151	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.074307 (rank : 254)
Query Neighborhood Hits	353	Target Neighborhood Hits	132	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

CBL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	353	Target Neighborhood Hits	353	Shared Neighborhood Hits	353
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
NC score	0.970121 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	353	Target Neighborhood Hits	426	Shared Neighborhood Hits	277
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBLB_HUMAN
NC score	0.954863 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	353	Target Neighborhood Hits	261	Shared Neighborhood Hits	193
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
NC score	0.954009 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	353	Target Neighborhood Hits	277	Shared Neighborhood Hits	194
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
NC score	0.935161 (rank : 5)	θ value	2.61662e-116 (rank : 5)
Query Neighborhood Hits	353	Target Neighborhood Hits	173	Shared Neighborhood Hits	151
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
NC score	0.932891 (rank : 6)	θ value	2.61662e-116 (rank : 6)
Query Neighborhood Hits	353	Target Neighborhood Hits	186	Shared Neighborhood Hits	156
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

PEX10_HUMAN
NC score	0.449416 (rank : 7)	θ value	3.19293e-05 (rank : 10)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	176
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN185_HUMAN
NC score	0.446706 (rank : 8)	θ value	2.44474e-05 (rank : 8)
Query Neighborhood Hits	353	Target Neighborhood Hits	213	Shared Neighborhood Hits	160
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.444946 (rank : 9)	θ value	2.44474e-05 (rank : 9)
Query Neighborhood Hits	353	Target Neighborhood Hits	211	Shared Neighborhood Hits	158
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF5_HUMAN
NC score	0.435679 (rank : 10)	θ value	2.88788e-06 (rank : 7)
Query Neighborhood Hits	353	Target Neighborhood Hits	206	Shared Neighborhood Hits	155
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.425463 (rank : 11)	θ value	3.19293e-05 (rank : 11)
Query Neighborhood Hits	353	Target Neighborhood Hits	206	Shared Neighborhood Hits	153
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RN141_HUMAN
NC score	0.321736 (rank : 12)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.320017 (rank : 13)	θ value	0.00509761 (rank : 27)
Query Neighborhood Hits	353	Target Neighborhood Hits	200	Shared Neighborhood Hits	135
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

AMFR_MOUSE
NC score	0.312413 (rank : 14)	θ value	0.00228821 (rank : 18)
Query Neighborhood Hits	353	Target Neighborhood Hits	208	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.310371 (rank : 15)	θ value	0.00228821 (rank : 17)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

CHFR_HUMAN
NC score	0.308418 (rank : 16)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	143
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
NC score	0.306216 (rank : 17)	θ value	0.00390308 (rank : 25)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	146
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN169_HUMAN
NC score	0.277530 (rank : 18)	θ value	0.0113563 (rank : 38)
Query Neighborhood Hits	353	Target Neighborhood Hits	203	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

BIRC7_HUMAN
NC score	0.276694 (rank : 19)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	353	Target Neighborhood Hits	185	Shared Neighborhood Hits	124
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

RN168_HUMAN
NC score	0.270466 (rank : 20)	θ value	0.0563607 (rank : 63)
Query Neighborhood Hits	353	Target Neighborhood Hits	370	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI65_HUMAN
NC score	0.269668 (rank : 21)	θ value	0.00228821 (rank : 23)
Query Neighborhood Hits	353	Target Neighborhood Hits	330	Shared Neighborhood Hits	169
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ZN364_HUMAN
NC score	0.268534 (rank : 22)	θ value	0.00175202 (rank : 16)
Query Neighborhood Hits	353	Target Neighborhood Hits	140	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

TRI40_HUMAN
NC score	0.267674 (rank : 23)	θ value	0.0113563 (rank : 39)
Query Neighborhood Hits	353	Target Neighborhood Hits	279	Shared Neighborhood Hits	148
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

RNF8_MOUSE
NC score	0.265962 (rank : 24)	θ value	0.00509761 (rank : 28)
Query Neighborhood Hits	353	Target Neighborhood Hits	618	Shared Neighborhood Hits	174
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF8_HUMAN
NC score	0.264101 (rank : 25)	θ value	0.00228821 (rank : 21)
Query Neighborhood Hits	353	Target Neighborhood Hits	622	Shared Neighborhood Hits	172
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RN125_HUMAN
NC score	0.261397 (rank : 26)	θ value	0.279714 (rank : 102)
Query Neighborhood Hits	353	Target Neighborhood Hits	230	Shared Neighborhood Hits	150
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN168_MOUSE
NC score	0.260676 (rank : 27)	θ value	0.0431538 (rank : 57)
Query Neighborhood Hits	353	Target Neighborhood Hits	440	Shared Neighborhood Hits	154
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN165_HUMAN
NC score	0.257505 (rank : 28)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	353	Target Neighborhood Hits	151	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

TRI65_MOUSE
NC score	0.248740 (rank : 29)	θ value	0.0330416 (rank : 51)
Query Neighborhood Hits	353	Target Neighborhood Hits	340	Shared Neighborhood Hits	172
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI56_HUMAN
NC score	0.248665 (rank : 30)	θ value	0.00869519 (rank : 36)
Query Neighborhood Hits	353	Target Neighborhood Hits	339	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

RN166_MOUSE
NC score	0.247328 (rank : 31)	θ value	0.163984 (rank : 89)
Query Neighborhood Hits	353	Target Neighborhood Hits	248	Shared Neighborhood Hits	144
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

ZN313_MOUSE
NC score	0.246872 (rank : 32)	θ value	0.47712 (rank : 127)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	159
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

ZN313_HUMAN
NC score	0.246695 (rank : 33)	θ value	0.365318 (rank : 117)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN364_MOUSE
NC score	0.245198 (rank : 34)	θ value	0.0148317 (rank : 43)
Query Neighborhood Hits	353	Target Neighborhood Hits	140	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

TRIM2_HUMAN
NC score	0.244018 (rank : 35)	θ value	0.00665767 (rank : 30)
Query Neighborhood Hits	353	Target Neighborhood Hits	330	Shared Neighborhood Hits	158
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.243250 (rank : 36)	θ value	0.00665767 (rank : 31)
Query Neighborhood Hits	353	Target Neighborhood Hits	331	Shared Neighborhood Hits	156
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RN125_MOUSE
NC score	0.242525 (rank : 37)	θ value	0.365318 (rank : 114)
Query Neighborhood Hits	353	Target Neighborhood Hits	220	Shared Neighborhood Hits	137
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN167_MOUSE
NC score	0.242005 (rank : 38)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	353	Target Neighborhood Hits	157	Shared Neighborhood Hits	95
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

TRI37_MOUSE
NC score	0.241848 (rank : 39)	θ value	0.0148317 (rank : 42)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	121
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

RN166_HUMAN
NC score	0.241680 (rank : 40)	θ value	0.163984 (rank : 88)
Query Neighborhood Hits	353	Target Neighborhood Hits	240	Shared Neighborhood Hits	142
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI37_HUMAN
NC score	0.241379 (rank : 41)	θ value	0.0148317 (rank : 41)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	120
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

RN167_HUMAN
NC score	0.238359 (rank : 42)	θ value	0.0736092 (rank : 70)
Query Neighborhood Hits	353	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN126_MOUSE
NC score	0.232643 (rank : 43)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	90
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

PML_HUMAN
NC score	0.232551 (rank : 44)	θ value	0.00228821 (rank : 20)
Query Neighborhood Hits	353	Target Neighborhood Hits	248	Shared Neighborhood Hits	96
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRI56_MOUSE
NC score	0.226227 (rank : 45)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	132
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

RNF13_MOUSE
NC score	0.225641 (rank : 46)	θ value	0.0431538 (rank : 58)
Query Neighborhood Hits	353	Target Neighborhood Hits	164	Shared Neighborhood Hits	95
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

TRIM3_HUMAN
NC score	0.224891 (rank : 47)	θ value	0.0563607 (rank : 64)
Query Neighborhood Hits	353	Target Neighborhood Hits	357	Shared Neighborhood Hits	147
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
NC score	0.224572 (rank : 48)	θ value	0.0431538 (rank : 61)
Query Neighborhood Hits	353	Target Neighborhood Hits	351	Shared Neighborhood Hits	147
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

RNF13_HUMAN
NC score	0.218888 (rank : 49)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	353	Target Neighborhood Hits	147	Shared Neighborhood Hits	91
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

TRI25_MOUSE
NC score	0.217756 (rank : 50)	θ value	0.0193708 (rank : 45)
Query Neighborhood Hits	353	Target Neighborhood Hits	446	Shared Neighborhood Hits	165
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

BIRC3_HUMAN
NC score	0.214631 (rank : 51)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	353	Target Neighborhood Hits	133	Shared Neighborhood Hits	85
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

RN133_HUMAN
NC score	0.213976 (rank : 52)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	353	Target Neighborhood Hits	108	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

BIRC3_MOUSE
NC score	0.213173 (rank : 53)	θ value	0.000786445 (rank : 12)
Query Neighborhood Hits	353	Target Neighborhood Hits	113	Shared Neighborhood Hits	74
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

NHLC1_MOUSE
NC score	0.211972 (rank : 54)	θ value	0.125558 (rank : 84)
Query Neighborhood Hits	353	Target Neighborhood Hits	103	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

MGRN1_MOUSE
NC score	0.209639 (rank : 55)	θ value	0.125558 (rank : 81)
Query Neighborhood Hits	353	Target Neighborhood Hits	149	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

GOLI_HUMAN
NC score	0.209006 (rank : 56)	θ value	0.0563607 (rank : 62)
Query Neighborhood Hits	353	Target Neighborhood Hits	137	Shared Neighborhood Hits	70
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

TRI25_HUMAN
NC score	0.208825 (rank : 57)	θ value	0.0330416 (rank : 50)
Query Neighborhood Hits	353	Target Neighborhood Hits	472	Shared Neighborhood Hits	153
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

BFAR_MOUSE
NC score	0.208817 (rank : 58)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	353	Target Neighborhood Hits	232	Shared Neighborhood Hits	137
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

MGRN1_HUMAN
NC score	0.208327 (rank : 59)	θ value	0.0961366 (rank : 72)
Query Neighborhood Hits	353	Target Neighborhood Hits	192	Shared Neighborhood Hits	108
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

RKHD1_HUMAN
NC score	0.207311 (rank : 60)	θ value	0.47712 (rank : 121)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	79
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

GOLI_MOUSE
NC score	0.206242 (rank : 61)	θ value	0.0736092 (rank : 66)
Query Neighborhood Hits	353	Target Neighborhood Hits	134	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

TRI35_HUMAN
NC score	0.204649 (rank : 62)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	353	Target Neighborhood Hits	382	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

BIRC2_MOUSE
NC score	0.204495 (rank : 63)	θ value	0.00175202 (rank : 15)
Query Neighborhood Hits	353	Target Neighborhood Hits	137	Shared Neighborhood Hits	79
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

TRI35_MOUSE
NC score	0.200874 (rank : 64)	θ value	0.279714 (rank : 104)
Query Neighborhood Hits	353	Target Neighborhood Hits	465	Shared Neighborhood Hits	160
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

BFAR_HUMAN
NC score	0.200509 (rank : 65)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	353	Target Neighborhood Hits	222	Shared Neighborhood Hits	133
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BIRC2_HUMAN
NC score	0.200449 (rank : 66)	θ value	0.00228821 (rank : 19)
Query Neighborhood Hits	353	Target Neighborhood Hits	142	Shared Neighborhood Hits	82
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

RNF26_HUMAN
NC score	0.199777 (rank : 67)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	353	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

TRI26_HUMAN
NC score	0.198647 (rank : 68)	θ value	0.21417 (rank : 97)
Query Neighborhood Hits	353	Target Neighborhood Hits	335	Shared Neighborhood Hits	161
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

NEURL_MOUSE
NC score	0.198192 (rank : 69)	θ value	0.0736092 (rank : 67)
Query Neighborhood Hits	353	Target Neighborhood Hits	106	Shared Neighborhood Hits	72
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

TRI32_HUMAN
NC score	0.198152 (rank : 70)	θ value	0.21417 (rank : 98)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	119
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.197126 (rank : 71)	θ value	0.21417 (rank : 99)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	119
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI26_MOUSE
NC score	0.196749 (rank : 72)	θ value	0.62314 (rank : 141)
Query Neighborhood Hits	353	Target Neighborhood Hits	339	Shared Neighborhood Hits	163
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

RN126_HUMAN
NC score	0.195293 (rank : 73)	θ value	0.62314 (rank : 138)
Query Neighborhood Hits	353	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

TRI13_MOUSE
NC score	0.194258 (rank : 74)	θ value	0.813845 (rank : 155)
Query Neighborhood Hits	353	Target Neighborhood Hits	282	Shared Neighborhood Hits	149
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

PML_MOUSE
NC score	0.193648 (rank : 75)	θ value	0.0736092 (rank : 68)
Query Neighborhood Hits	353	Target Neighborhood Hits	246	Shared Neighborhood Hits	90
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI39_HUMAN
NC score	0.191774 (rank : 76)	θ value	0.00869519 (rank : 34)
Query Neighborhood Hits	353	Target Neighborhood Hits	693	Shared Neighborhood Hits	180
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

NEUL1_HUMAN
NC score	0.191302 (rank : 77)	θ value	0.163984 (rank : 87)
Query Neighborhood Hits	353	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

TRI39_MOUSE
NC score	0.189988 (rank : 78)	θ value	0.00869519 (rank : 35)
Query Neighborhood Hits	353	Target Neighborhood Hits	691	Shared Neighborhood Hits	177
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RING1_HUMAN
NC score	0.189870 (rank : 79)	θ value	0.62314 (rank : 132)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	124
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.187862 (rank : 80)	θ value	0.62314 (rank : 133)
Query Neighborhood Hits	353	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI60_HUMAN
NC score	0.187516 (rank : 81)	θ value	0.0431538 (rank : 60)
Query Neighborhood Hits	353	Target Neighborhood Hits	357	Shared Neighborhood Hits	155
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

RNF41_MOUSE
NC score	0.187201 (rank : 82)	θ value	2.36792 (rank : 207)
Query Neighborhood Hits	353	Target Neighborhood Hits	224	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.187057 (rank : 83)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	353	Target Neighborhood Hits	226	Shared Neighborhood Hits	133
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRI13_HUMAN
NC score	0.186808 (rank : 84)	θ value	1.06291 (rank : 172)
Query Neighborhood Hits	353	Target Neighborhood Hits	274	Shared Neighborhood Hits	147
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

RNF4_HUMAN
NC score	0.186490 (rank : 85)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	353	Target Neighborhood Hits	212	Shared Neighborhood Hits	142
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.185379 (rank : 86)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	353	Target Neighborhood Hits	212	Shared Neighborhood Hits	142
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI47_MOUSE
NC score	0.181445 (rank : 87)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	353	Target Neighborhood Hits	295	Shared Neighborhood Hits	139
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI15_HUMAN
NC score	0.181327 (rank : 88)	θ value	0.00665767 (rank : 29)
Query Neighborhood Hits	353	Target Neighborhood Hits	395	Shared Neighborhood Hits	131
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI73_HUMAN
NC score	0.180923 (rank : 89)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	353	Target Neighborhood Hits	258	Shared Neighborhood Hits	147
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI47_HUMAN
NC score	0.180208 (rank : 90)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	140
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI31_HUMAN
NC score	0.179754 (rank : 91)	θ value	6.88961 (rank : 305)
Query Neighborhood Hits	353	Target Neighborhood Hits	299	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

RING2_MOUSE
NC score	0.178360 (rank : 92)	θ value	0.62314 (rank : 135)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	121
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.178249 (rank : 93)	θ value	0.62314 (rank : 134)
Query Neighborhood Hits	353	Target Neighborhood Hits	201	Shared Neighborhood Hits	121
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

TRI74_HUMAN
NC score	0.177205 (rank : 94)	θ value	2.36792 (rank : 215)
Query Neighborhood Hits	353	Target Neighborhood Hits	249	Shared Neighborhood Hits	138
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI50_HUMAN
NC score	0.177089 (rank : 95)	θ value	0.47712 (rank : 126)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	149
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RN122_MOUSE
NC score	0.176373 (rank : 96)	θ value	1.06291 (rank : 168)
Query Neighborhood Hits	353	Target Neighborhood Hits	121	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RFFL_HUMAN
NC score	0.176087 (rank : 97)	θ value	0.21417 (rank : 94)
Query Neighborhood Hits	353	Target Neighborhood Hits	175	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
NC score	0.175208 (rank : 98)	θ value	0.21417 (rank : 95)
Query Neighborhood Hits	353	Target Neighborhood Hits	145	Shared Neighborhood Hits	76
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

TRI59_MOUSE
NC score	0.174045 (rank : 99)	θ value	1.06291 (rank : 173)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	143
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

RNF24_MOUSE
NC score	0.172237 (rank : 100)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	353	Target Neighborhood Hits	124	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

BRCA1_MOUSE
NC score	0.172023 (rank : 101)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	353	Target Neighborhood Hits	436	Shared Neighborhood Hits	149
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TRI59_HUMAN
NC score	0.171847 (rank : 102)	θ value	1.38821 (rank : 186)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	144
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI50_MOUSE
NC score	0.171541 (rank : 103)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	353	Target Neighborhood Hits	326	Shared Neighborhood Hits	159
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RN103_HUMAN
NC score	0.170746 (rank : 104)	θ value	0.62314 (rank : 136)
Query Neighborhood Hits	353	Target Neighborhood Hits	153	Shared Neighborhood Hits	90
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
NC score	0.170479 (rank : 105)	θ value	0.62314 (rank : 137)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RNF24_HUMAN
NC score	0.169925 (rank : 106)	θ value	1.06291 (rank : 169)
Query Neighborhood Hits	353	Target Neighborhood Hits	122	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

TRI30_MOUSE
NC score	0.168967 (rank : 107)	θ value	0.47712 (rank : 125)
Query Neighborhood Hits	353	Target Neighborhood Hits	434	Shared Neighborhood Hits	139
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI43_HUMAN
NC score	0.168536 (rank : 108)	θ value	0.813845 (rank : 156)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	148
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

SMRA3_MOUSE
NC score	0.167263 (rank : 109)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	144
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

NHLC1_HUMAN
NC score	0.167097 (rank : 110)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	353	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRI10_HUMAN
NC score	0.166235 (rank : 111)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	353	Target Neighborhood Hits	315	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

RO52_MOUSE
NC score	0.165153 (rank : 112)	θ value	0.47712 (rank : 122)
Query Neighborhood Hits	353	Target Neighborhood Hits	360	Shared Neighborhood Hits	154
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI68_MOUSE
NC score	0.164465 (rank : 113)	θ value	0.62314 (rank : 143)
Query Neighborhood Hits	353	Target Neighborhood Hits	356	Shared Neighborhood Hits	147
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

RO52_HUMAN
NC score	0.163936 (rank : 114)	θ value	0.813845 (rank : 154)
Query Neighborhood Hits	353	Target Neighborhood Hits	419	Shared Neighborhood Hits	165
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI60_MOUSE
NC score	0.162785 (rank : 115)	θ value	0.813845 (rank : 157)
Query Neighborhood Hits	353	Target Neighborhood Hits	240	Shared Neighborhood Hits	126
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

BRCA1_HUMAN
NC score	0.161741 (rank : 116)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	353	Target Neighborhood Hits	381	Shared Neighborhood Hits	140
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BIRC8_HUMAN
NC score	0.161420 (rank : 117)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	353	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

TRI10_MOUSE
NC score	0.161158 (rank : 118)	θ value	1.81305 (rank : 197)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI11_HUMAN
NC score	0.160412 (rank : 119)	θ value	0.365318 (rank : 115)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	145
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

RNF37_MOUSE
NC score	0.160348 (rank : 120)	θ value	0.163984 (rank : 90)
Query Neighborhood Hits	353	Target Neighborhood Hits	102	Shared Neighborhood Hits	52
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

TRI11_MOUSE
NC score	0.159841 (rank : 121)	θ value	0.365318 (rank : 116)
Query Neighborhood Hits	353	Target Neighborhood Hits	329	Shared Neighborhood Hits	149
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI62_MOUSE
NC score	0.158987 (rank : 122)	θ value	0.279714 (rank : 106)
Query Neighborhood Hits	353	Target Neighborhood Hits	478	Shared Neighborhood Hits	141
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM4_HUMAN
NC score	0.158069 (rank : 123)	θ value	4.03905 (rank : 245)
Query Neighborhood Hits	353	Target Neighborhood Hits	321	Shared Neighborhood Hits	145
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

ZN179_HUMAN
NC score	0.158035 (rank : 124)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	353	Target Neighborhood Hits	178	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI68_HUMAN
NC score	0.157893 (rank : 125)	θ value	0.62314 (rank : 142)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	135
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

PZRN3_MOUSE
NC score	0.157774 (rank : 126)	θ value	0.0431538 (rank : 56)
Query Neighborhood Hits	353	Target Neighborhood Hits	447	Shared Neighborhood Hits	155
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.157636 (rank : 127)	θ value	0.0431538 (rank : 55)
Query Neighborhood Hits	353	Target Neighborhood Hits	461	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRI17_HUMAN
NC score	0.157333 (rank : 128)	θ value	0.62314 (rank : 140)
Query Neighborhood Hits	353	Target Neighborhood Hits	318	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

PJA1_HUMAN
NC score	0.157247 (rank : 129)	θ value	3.0926 (rank : 224)
Query Neighborhood Hits	353	Target Neighborhood Hits	159	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PZRN4_HUMAN
NC score	0.156852 (rank : 130)	θ value	0.0736092 (rank : 69)
Query Neighborhood Hits	353	Target Neighborhood Hits	438	Shared Neighborhood Hits	153
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PJA1_MOUSE
NC score	0.156561 (rank : 131)	θ value	3.0926 (rank : 225)
Query Neighborhood Hits	353	Target Neighborhood Hits	145	Shared Neighborhood Hits	77
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

TRIM5_HUMAN
NC score	0.156120 (rank : 132)	θ value	5.27518 (rank : 279)
Query Neighborhood Hits	353	Target Neighborhood Hits	424	Shared Neighborhood Hits	153
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

DZIP3_MOUSE
NC score	0.155876 (rank : 133)	θ value	0.0431538 (rank : 52)
Query Neighborhood Hits	353	Target Neighborhood Hits	414	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

TRI62_HUMAN
NC score	0.155518 (rank : 134)	θ value	0.279714 (rank : 105)
Query Neighborhood Hits	353	Target Neighborhood Hits	584	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RN122_HUMAN
NC score	0.154928 (rank : 135)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	353	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

TOPRS_MOUSE
NC score	0.152939 (rank : 136)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	353	Target Neighborhood Hits	263	Shared Neighborhood Hits	131
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI12_MOUSE
NC score	0.152103 (rank : 137)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	353	Target Neighborhood Hits	387	Shared Neighborhood Hits	142
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI52_HUMAN
NC score	0.150866 (rank : 138)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	353	Target Neighborhood Hits	213	Shared Neighborhood Hits	126
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

RNF34_MOUSE
NC score	0.149705 (rank : 139)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	353	Target Neighborhood Hits	160	Shared Neighborhood Hits	83
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.149451 (rank : 140)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	353	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

TOPRS_HUMAN
NC score	0.149255 (rank : 141)	θ value	2.36792 (rank : 208)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRIM7_MOUSE
NC score	0.148796 (rank : 142)	θ value	5.27518 (rank : 280)
Query Neighborhood Hits	353	Target Neighborhood Hits	358	Shared Neighborhood Hits	126
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

BIRC4_HUMAN
NC score	0.148326 (rank : 143)	θ value	0.365318 (rank : 110)
Query Neighborhood Hits	353	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

DZIP3_HUMAN
NC score	0.144280 (rank : 144)	θ value	0.279714 (rank : 100)
Query Neighborhood Hits	353	Target Neighborhood Hits	399	Shared Neighborhood Hits	82
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

TRIM7_HUMAN
NC score	0.143902 (rank : 145)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	353	Target Neighborhood Hits	336	Shared Neighborhood Hits	128
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

BIRC4_MOUSE
NC score	0.143098 (rank : 146)	θ value	0.813845 (rank : 144)
Query Neighborhood Hits	353	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

TRI27_HUMAN
NC score	0.142933 (rank : 147)	θ value	4.03905 (rank : 244)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	143
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.139442 (rank : 148)	θ value	5.27518 (rank : 278)
Query Neighborhood Hits	353	Target Neighborhood Hits	261	Shared Neighborhood Hits	136
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI17_MOUSE
NC score	0.137897 (rank : 149)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	353	Target Neighborhood Hits	620	Shared Neighborhood Hits	145
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRAF6_HUMAN
NC score	0.137883 (rank : 150)	θ value	2.36792 (rank : 210)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
NC score	0.137420 (rank : 151)	θ value	2.36792 (rank : 211)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	124
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAIP_HUMAN
NC score	0.136740 (rank : 152)	θ value	0.125558 (rank : 85)
Query Neighborhood Hits	353	Target Neighborhood Hits	780	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRI22_HUMAN
NC score	0.136228 (rank : 153)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	353	Target Neighborhood Hits	396	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

RN123_MOUSE
NC score	0.136228 (rank : 154)	θ value	0.279714 (rank : 101)
Query Neighborhood Hits	353	Target Neighborhood Hits	174	Shared Neighborhood Hits	96
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

SMRA3_HUMAN
NC score	0.134931 (rank : 155)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	353	Target Neighborhood Hits	265	Shared Neighborhood Hits	143
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRIM6_MOUSE
NC score	0.133104 (rank : 156)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	353	Target Neighborhood Hits	451	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM6_HUMAN
NC score	0.133088 (rank : 157)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	353	Target Neighborhood Hits	412	Shared Neighborhood Hits	135
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

RN123_HUMAN
NC score	0.131968 (rank : 158)	θ value	0.365318 (rank : 113)
Query Neighborhood Hits	353	Target Neighborhood Hits	175	Shared Neighborhood Hits	96
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRIM8_HUMAN
NC score	0.130829 (rank : 159)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	353	Target Neighborhood Hits	650	Shared Neighborhood Hits	137
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRAIP_MOUSE
NC score	0.130638 (rank : 160)	θ value	0.125558 (rank : 86)
Query Neighborhood Hits	353	Target Neighborhood Hits	745	Shared Neighborhood Hits	98
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

MYLIP_HUMAN
NC score	0.130500 (rank : 161)	θ value	0.0431538 (rank : 54)
Query Neighborhood Hits	353	Target Neighborhood Hits	162	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

LNX1_MOUSE
NC score	0.130492 (rank : 162)	θ value	0.0961366 (rank : 71)
Query Neighborhood Hits	353	Target Neighborhood Hits	377	Shared Neighborhood Hits	131
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRIM8_MOUSE
NC score	0.130307 (rank : 163)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	353	Target Neighborhood Hits	674	Shared Neighborhood Hits	139
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RAG1_MOUSE
NC score	0.129838 (rank : 164)	θ value	3.0926 (rank : 227)
Query Neighborhood Hits	353	Target Neighborhood Hits	189	Shared Neighborhood Hits	112
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

LNX1_HUMAN
NC score	0.128590 (rank : 165)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	353	Target Neighborhood Hits	379	Shared Neighborhood Hits	143
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRI38_HUMAN
NC score	0.128368 (rank : 166)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	353	Target Neighborhood Hits	373	Shared Neighborhood Hits	127
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI34_HUMAN
NC score	0.124671 (rank : 167)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	353	Target Neighborhood Hits	416	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

RN139_MOUSE
NC score	0.123038 (rank : 168)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	353	Target Neighborhood Hits	131	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

TRI41_HUMAN
NC score	0.120383 (rank : 169)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	353	Target Neighborhood Hits	349	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

CM007_MOUSE
NC score	0.120030 (rank : 170)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	353	Target Neighborhood Hits	416	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TRI48_HUMAN
NC score	0.119763 (rank : 171)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	353	Target Neighborhood Hits	192	Shared Neighborhood Hits	113
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

RN146_HUMAN
NC score	0.118256 (rank : 172)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	353	Target Neighborhood Hits	162	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RAG1_HUMAN
NC score	0.117715 (rank : 173)	θ value	8.99809 (rank : 335)
Query Neighborhood Hits	353	Target Neighborhood Hits	203	Shared Neighborhood Hits	111
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RN146_MOUSE
NC score	0.117391 (rank : 174)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	353	Target Neighborhood Hits	161	Shared Neighborhood Hits	114
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRI34_MOUSE
NC score	0.115965 (rank : 175)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	353	Target Neighborhood Hits	332	Shared Neighborhood Hits	110
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI49_HUMAN
NC score	0.115890 (rank : 176)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI54_HUMAN
NC score	0.114591 (rank : 177)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	353	Target Neighborhood Hits	209	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
NC score	0.113022 (rank : 178)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	353	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

MYLIP_MOUSE
NC score	0.111302 (rank : 179)	θ value	0.125558 (rank : 83)
Query Neighborhood Hits	353	Target Neighborhood Hits	139	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

TRIM1_MOUSE
NC score	0.110368 (rank : 180)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	353	Target Neighborhood Hits	361	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

RNF12_MOUSE
NC score	0.110339 (rank : 181)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	353	Target Neighborhood Hits	159	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

TRIM1_HUMAN
NC score	0.110227 (rank : 182)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	353	Target Neighborhood Hits	345	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

CM007_HUMAN
NC score	0.109526 (rank : 183)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	353	Target Neighborhood Hits	422	Shared Neighborhood Hits	113
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

RNF39_HUMAN
NC score	0.108372 (rank : 184)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	353	Target Neighborhood Hits	200	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RFWD2_MOUSE
NC score	0.108170 (rank : 185)	θ value	8.99809 (rank : 337)
Query Neighborhood Hits	353	Target Neighborhood Hits	535	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRI18_MOUSE
NC score	0.107058 (rank : 186)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	136
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

RFWD2_HUMAN
NC score	0.106836 (rank : 187)	θ value	8.99809 (rank : 336)
Query Neighborhood Hits	353	Target Neighborhood Hits	518	Shared Neighborhood Hits	151
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

TRI18_HUMAN
NC score	0.106517 (rank : 188)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	134
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

LNX2_HUMAN
NC score	0.105168 (rank : 189)	θ value	3.0926 (rank : 222)
Query Neighborhood Hits	353	Target Neighborhood Hits	389	Shared Neighborhood Hits	136
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RNF38_HUMAN
NC score	0.105142 (rank : 190)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	353	Target Neighborhood Hits	155	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

TRI63_HUMAN
NC score	0.105052 (rank : 191)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	353	Target Neighborhood Hits	298	Shared Neighborhood Hits	105
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
NC score	0.105027 (rank : 192)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	353	Target Neighborhood Hits	240	Shared Neighborhood Hits	104
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

RAD18_MOUSE
NC score	0.104382 (rank : 193)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	353	Target Neighborhood Hits	230	Shared Neighborhood Hits	106
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RN139_HUMAN
NC score	0.104270 (rank : 194)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	353	Target Neighborhood Hits	130	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RNF11_HUMAN
NC score	0.103860 (rank : 195)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	353	Target Neighborhood Hits	81	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
NC score	0.103402 (rank : 196)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	353	Target Neighborhood Hits	81	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

ZN363_MOUSE
NC score	0.103165 (rank : 197)	θ value	4.03905 (rank : 251)
Query Neighborhood Hits	353	Target Neighborhood Hits	134	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

RNF38_MOUSE
NC score	0.102671 (rank : 198)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	353	Target Neighborhood Hits	153	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF37_HUMAN
NC score	0.102640 (rank : 199)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	353	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

RNF12_HUMAN
NC score	0.102551 (rank : 200)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	353	Target Neighborhood Hits	173	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

LNX2_MOUSE
NC score	0.102263 (rank : 201)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	353	Target Neighborhood Hits	407	Shared Neighborhood Hits	141
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RAD18_HUMAN
NC score	0.101944 (rank : 202)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RBBP6_MOUSE
NC score	0.100495 (rank : 203)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	353	Target Neighborhood Hits	1014	Shared Neighborhood Hits	147
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRI55_HUMAN
NC score	0.100179 (rank : 204)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

BRAP_HUMAN
NC score	0.098093 (rank : 205)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	353	Target Neighborhood Hits	560	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
NC score	0.097856 (rank : 206)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	353	Target Neighborhood Hits	409	Shared Neighborhood Hits	78
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

SRRM2_MOUSE
NC score	0.097262 (rank : 207)	θ value	0.00228821 (rank : 22)
Query Neighborhood Hits	353	Target Neighborhood Hits	1470	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RNF6_HUMAN
NC score	0.095977 (rank : 208)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	353	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

DTX3_HUMAN
NC score	0.095234 (rank : 209)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	353	Target Neighborhood Hits	198	Shared Neighborhood Hits	122
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RNF32_HUMAN
NC score	0.094860 (rank : 210)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	353	Target Neighborhood Hits	133	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

DTX3_MOUSE
NC score	0.093559 (rank : 211)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	353	Target Neighborhood Hits	202	Shared Neighborhood Hits	123
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

SRRM2_HUMAN
NC score	0.093481 (rank : 212)	θ value	0.00869519 (rank : 33)
Query Neighborhood Hits	353	Target Neighborhood Hits	1296	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MEFV_MOUSE
NC score	0.091993 (rank : 213)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	353	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_HUMAN
NC score	0.091855 (rank : 214)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	353	Target Neighborhood Hits	431	Shared Neighborhood Hits	74
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

RN183_HUMAN
NC score	0.090994 (rank : 215)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	353	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

CO039_MOUSE
NC score	0.090753 (rank : 216)	θ value	0.47712 (rank : 120)
Query Neighborhood Hits	353	Target Neighborhood Hits	445	Shared Neighborhood Hits	65
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

TRAF4_HUMAN
NC score	0.090301 (rank : 217)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	353	Target Neighborhood Hits	373	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

RBBP6_HUMAN
NC score	0.089345 (rank : 218)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	353	Target Neighborhood Hits	1135	Shared Neighborhood Hits	144
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TIF1B_MOUSE
NC score	0.089008 (rank : 219)	θ value	6.88961 (rank : 302)
Query Neighborhood Hits	353	Target Neighborhood Hits	276	Shared Neighborhood Hits	75
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

R113A_HUMAN
NC score	0.088329 (rank : 220)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	353	Target Neighborhood Hits	177	Shared Neighborhood Hits	97
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TIF1B_HUMAN
NC score	0.087964 (rank : 221)	θ value	6.88961 (rank : 301)
Query Neighborhood Hits	353	Target Neighborhood Hits	312	Shared Neighborhood Hits	83
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRAF4_MOUSE
NC score	0.087844 (rank : 222)	θ value	4.03905 (rank : 243)
Query Neighborhood Hits	353	Target Neighborhood Hits	338	Shared Neighborhood Hits	94
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRIM9_HUMAN
NC score	0.085781 (rank : 223)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	105
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRI16_MOUSE
NC score	0.085719 (rank : 224)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	57
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRIM9_MOUSE
NC score	0.085640 (rank : 225)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	353	Target Neighborhood Hits	274	Shared Neighborhood Hits	105
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI14_HUMAN
NC score	0.084447 (rank : 226)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

RNF32_MOUSE
NC score	0.084254 (rank : 227)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	353	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

BSPRY_MOUSE
NC score	0.084136 (rank : 228)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

ZN363_HUMAN
NC score	0.083634 (rank : 229)	θ value	4.03905 (rank : 250)
Query Neighborhood Hits	353	Target Neighborhood Hits	162	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

RN183_MOUSE
NC score	0.082985 (rank : 230)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	353	Target Neighborhood Hits	119	Shared Neighborhood Hits	74
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI14_MOUSE
NC score	0.082980 (rank : 231)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	353	Target Neighborhood Hits	137	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI46_HUMAN
NC score	0.081941 (rank : 232)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
NC score	0.081652 (rank : 233)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	353	Target Neighborhood Hits	287	Shared Neighborhood Hits	114
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

UHRF2_HUMAN
NC score	0.081271 (rank : 234)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	353	Target Neighborhood Hits	269	Shared Neighborhood Hits	124
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

CCD95_HUMAN
NC score	0.081165 (rank : 235)	θ value	0.21417 (rank : 92)
Query Neighborhood Hits	353	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

R113B_HUMAN
NC score	0.079823 (rank : 236)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RFPL3_HUMAN
NC score	0.079737 (rank : 237)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	353	Target Neighborhood Hits	134	Shared Neighborhood Hits	72
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

TRAF3_MOUSE
NC score	0.079652 (rank : 238)	θ value	6.88961 (rank : 304)
Query Neighborhood Hits	353	Target Neighborhood Hits	476	Shared Neighborhood Hits	111
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

RFPL2_HUMAN
NC score	0.079148 (rank : 239)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	353	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRI16_HUMAN
NC score	0.078578 (rank : 240)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	353	Target Neighborhood Hits	231	Shared Neighborhood Hits	57
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

UHRF2_MOUSE
NC score	0.078489 (rank : 241)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	353	Target Neighborhood Hits	275	Shared Neighborhood Hits	120
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

RN152_MOUSE
NC score	0.078417 (rank : 242)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	353	Target Neighborhood Hits	109	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

MLL3_HUMAN
NC score	0.078181 (rank : 243)	θ value	2.36792 (rank : 203)
Query Neighborhood Hits	353	Target Neighborhood Hits	1644	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TRAF2_MOUSE
NC score	0.078137 (rank : 244)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	353	Target Neighborhood Hits	394	Shared Neighborhood Hits	101
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

BSPRY_HUMAN
NC score	0.077845 (rank : 245)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	353	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

DTX3L_HUMAN
NC score	0.077837 (rank : 246)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	353	Target Neighborhood Hits	187	Shared Neighborhood Hits	96
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RFPL1_HUMAN
NC score	0.076698 (rank : 247)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	353	Target Neighborhood Hits	119	Shared Neighborhood Hits	61
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

PCGF2_MOUSE
NC score	0.076542 (rank : 248)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	353	Target Neighborhood Hits	213	Shared Neighborhood Hits	109
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.076472 (rank : 249)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	353	Target Neighborhood Hits	222	Shared Neighborhood Hits	109
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

ERMAP_HUMAN
NC score	0.075653 (rank : 250)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	353	Target Neighborhood Hits	155	Shared Neighborhood Hits	40
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

YLPM1_HUMAN
NC score	0.074913 (rank : 251)	θ value	0.0961366 (rank : 77)
Query Neighborhood Hits	353	Target Neighborhood Hits	670	Shared Neighborhood Hits	67
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

TRI29_MOUSE
NC score	0.074760 (rank : 252)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	353	Target Neighborhood Hits	306	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

RN152_HUMAN
NC score	0.074549 (rank : 253)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	353	Target Neighborhood Hits	107	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

ZSWM2_MOUSE
NC score	0.074307 (rank : 254)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	353	Target Neighborhood Hits	132	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

TRAF5_MOUSE
NC score	0.073924 (rank : 255)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	353	Target Neighborhood Hits	355	Shared Neighborhood Hits	100
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

BRE1B_MOUSE
NC score	0.073137 (rank : 256)	θ value	1.06291 (rank : 161)
Query Neighborhood Hits	353	Target Neighborhood Hits	970	Shared Neighborhood Hits	126
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

TRI45_HUMAN
NC score	0.072725 (rank : 257)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	353	Target Neighborhood Hits	155	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI29_HUMAN
NC score	0.072633 (rank : 258)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	57
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

PCGF6_HUMAN
NC score	0.072220 (rank : 259)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	353	Target Neighborhood Hits	178	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

BRE1B_HUMAN
NC score	0.072054 (rank : 260)	θ value	1.06291 (rank : 160)
Query Neighborhood Hits	353	Target Neighborhood Hits	1040	Shared Neighborhood Hits	130
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

TRI36_HUMAN
NC score	0.072018 (rank : 261)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	353	Target Neighborhood Hits	282	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

WASIP_MOUSE
NC score	0.071650 (rank : 262)	θ value	1.06291 (rank : 174)
Query Neighborhood Hits	353	Target Neighborhood Hits	392	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

TRI45_MOUSE
NC score	0.071586 (rank : 263)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	353	Target Neighborhood Hits	155	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

ZSWM2_HUMAN
NC score	0.071213 (rank : 264)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	353	Target Neighborhood Hits	151	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

LRSM1_MOUSE
NC score	0.071195 (rank : 265)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	353	Target Neighborhood Hits	874	Shared Neighborhood Hits	101
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

TIF1G_MOUSE
NC score	0.070831 (rank : 266)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	353	Target Neighborhood Hits	498	Shared Neighborhood Hits	101
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

PCGF6_MOUSE
NC score	0.070790 (rank : 267)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	90
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRAF7_HUMAN
NC score	0.070367 (rank : 268)	θ value	5.27518 (rank : 276)
Query Neighborhood Hits	353	Target Neighborhood Hits	482	Shared Neighborhood Hits	126
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

PCGF4_HUMAN
NC score	0.070324 (rank : 269)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	353	Target Neighborhood Hits	161	Shared Neighborhood Hits	104
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

TRAF7_MOUSE
NC score	0.070301 (rank : 270)	θ value	5.27518 (rank : 277)
Query Neighborhood Hits	353	Target Neighborhood Hits	470	Shared Neighborhood Hits	123
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

ALEX_HUMAN
NC score	0.070153 (rank : 271)	θ value	1.38821 (rank : 176)
Query Neighborhood Hits	353	Target Neighborhood Hits	361	Shared Neighborhood Hits	46
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

PCGF4_MOUSE
NC score	0.070059 (rank : 272)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	102
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

TRI36_MOUSE
NC score	0.069809 (rank : 273)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	353	Target Neighborhood Hits	266	Shared Neighborhood Hits	97
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TIF1G_HUMAN
NC score	0.069388 (rank : 274)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	353	Target Neighborhood Hits	410	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

ERMAP_MOUSE
NC score	0.069243 (rank : 275)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	353	Target Neighborhood Hits	231	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

MIB1_MOUSE
NC score	0.068829 (rank : 276)	θ value	0.813845 (rank : 148)
Query Neighborhood Hits	353	Target Neighborhood Hits	471	Shared Neighborhood Hits	97
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

NACAM_MOUSE
NC score	0.068509 (rank : 277)	θ value	0.21417 (rank : 93)
Query Neighborhood Hits	353	Target Neighborhood Hits	1866	Shared Neighborhood Hits	122
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TRI44_MOUSE
NC score	0.068294 (rank : 278)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	353	Target Neighborhood Hits	327	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI44_HUMAN
NC score	0.067401 (rank : 279)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	353	Target Neighborhood Hits	393	Shared Neighborhood Hits	55
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

SGIP1_HUMAN
NC score	0.067390 (rank : 280)	θ value	0.47712 (rank : 123)
Query Neighborhood Hits	353	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

PS1C2_MOUSE
NC score	0.066919 (rank : 281)	θ value	3.0926 (rank : 226)
Query Neighborhood Hits	353	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

WASIP_HUMAN
NC score	0.066653 (rank : 282)	θ value	1.38821 (rank : 187)
Query Neighborhood Hits	353	Target Neighborhood Hits	458	Shared Neighborhood Hits	53
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ALEX_MOUSE
NC score	0.066126 (rank : 283)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	353	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BT1A1_MOUSE
NC score	0.066121 (rank : 284)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	353	Target Neighborhood Hits	252	Shared Neighborhood Hits	41
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

UHRF1_HUMAN
NC score	0.065918 (rank : 285)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	353	Target Neighborhood Hits	272	Shared Neighborhood Hits	114
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

BT3A3_HUMAN
NC score	0.065627 (rank : 286)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	353	Target Neighborhood Hits	233	Shared Neighborhood Hits	43
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT2A2_HUMAN
NC score	0.065317 (rank : 287)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	353	Target Neighborhood Hits	191	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRAF5_HUMAN
NC score	0.065002 (rank : 288)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	353	Target Neighborhood Hits	396	Shared Neighborhood Hits	94
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

MLL3_MOUSE
NC score	0.064884 (rank : 289)	θ value	5.27518 (rank : 266)
Query Neighborhood Hits	353	Target Neighborhood Hits	1399	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CN032_MOUSE
NC score	0.064762 (rank : 290)	θ value	0.125558 (rank : 78)
Query Neighborhood Hits	353	Target Neighborhood Hits	233	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

TRAF2_HUMAN
NC score	0.064736 (rank : 291)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	353	Target Neighborhood Hits	402	Shared Neighborhood Hits	94
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

BTNL9_HUMAN
NC score	0.064732 (rank : 292)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	353	Target Neighborhood Hits	125	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BT3A1_HUMAN
NC score	0.064470 (rank : 293)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	353	Target Neighborhood Hits	229	Shared Neighborhood Hits	40
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT1A1_HUMAN
NC score	0.064253 (rank : 294)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	353	Target Neighborhood Hits	322	Shared Neighborhood Hits	40
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

RN175_HUMAN
NC score	0.063982 (rank : 295)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	353	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

UHRF1_MOUSE
NC score	0.063897 (rank : 296)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	353	Target Neighborhood Hits	278	Shared Neighborhood Hits	116
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

BT2A1_HUMAN
NC score	0.063301 (rank : 297)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	353	Target Neighborhood Hits	185	Shared Neighborhood Hits	40
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BTNL3_HUMAN
NC score	0.062981 (rank : 298)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BT2A3_HUMAN
NC score	0.062356 (rank : 299)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	353	Target Neighborhood Hits	195	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

CJ012_HUMAN
NC score	0.061918 (rank : 300)	θ value	0.62314 (rank : 131)
Query Neighborhood Hits	353	Target Neighborhood Hits	467	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

TRAF3_HUMAN
NC score	0.061904 (rank : 301)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	353	Target Neighborhood Hits	463	Shared Neighborhood Hits	100
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

SGIP1_MOUSE
NC score	0.061790 (rank : 302)	θ value	6.88961 (rank : 298)
Query Neighborhood Hits	353	Target Neighborhood Hits	180	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

BCL9_HUMAN
NC score	0.061640 (rank : 303)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	353	Target Neighborhood Hits	1008	Shared Neighborhood Hits	94
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MILK1_MOUSE
NC score	0.061584 (rank : 304)	θ value	0.0113563 (rank : 37)
Query Neighborhood Hits	353	Target Neighborhood Hits	788	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TRI42_HUMAN
NC score	0.061373 (rank : 305)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	353	Target Neighborhood Hits	283	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

BTNL8_HUMAN
NC score	0.061333 (rank : 306)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	353	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

SPRY4_MOUSE
NC score	0.061169 (rank : 307)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	353	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

MIB1_HUMAN
NC score	0.060504 (rank : 308)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	353	Target Neighborhood Hits	470	Shared Neighborhood Hits	96
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

CBP_MOUSE
NC score	0.060421 (rank : 309)	θ value	0.365318 (rank : 111)
Query Neighborhood Hits	353	Target Neighborhood Hits	1051	Shared Neighborhood Hits	88
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TTC3_HUMAN
NC score	0.060297 (rank : 310)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	353	Target Neighborhood Hits	664	Shared Neighborhood Hits	75
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TRI42_MOUSE
NC score	0.059860 (rank : 311)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

SPRY4_HUMAN
NC score	0.059490 (rank : 312)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	353	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

MKRN3_HUMAN
NC score	0.059300 (rank : 313)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	70
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

CO039_HUMAN
NC score	0.058954 (rank : 314)	θ value	0.365318 (rank : 112)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

MDC1_HUMAN
NC score	0.058926 (rank : 315)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	353	Target Neighborhood Hits	1446	Shared Neighborhood Hits	99
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RAPH1_HUMAN
NC score	0.058179 (rank : 316)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	353	Target Neighborhood Hits	593	Shared Neighborhood Hits	59
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CBP_HUMAN
NC score	0.058035 (rank : 317)	θ value	3.0926 (rank : 219)
Query Neighborhood Hits	353	Target Neighborhood Hits	941	Shared Neighborhood Hits	80
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CGRF1_HUMAN
NC score	0.057891 (rank : 318)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	353	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

BRE1A_HUMAN
NC score	0.057530 (rank : 319)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	353	Target Neighborhood Hits	1071	Shared Neighborhood Hits	115
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
NC score	0.057274 (rank : 320)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	353	Target Neighborhood Hits	1025	Shared Neighborhood Hits	110
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

NCOA6_MOUSE
NC score	0.057106 (rank : 321)	θ value	6.88961 (rank : 294)
Query Neighborhood Hits	353	Target Neighborhood Hits	1076	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RBX2_MOUSE
NC score	0.055425 (rank : 322)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	353	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RBX2_HUMAN
NC score	0.055287 (rank : 323)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	353	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

WASL_MOUSE
NC score	0.054632 (rank : 324)	θ value	0.279714 (rank : 107)
Query Neighborhood Hits	353	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MKRN4_HUMAN
NC score	0.053862 (rank : 325)	θ value	8.99809 (rank : 328)
Query Neighborhood Hits	353	Target Neighborhood Hits	147	Shared Neighborhood Hits	78
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

BCL9_MOUSE
NC score	0.053735 (rank : 326)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	353	Target Neighborhood Hits	770	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CGRF1_MOUSE
NC score	0.053385 (rank : 327)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	353	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

PRRT3_HUMAN
NC score	0.053268 (rank : 328)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	353	Target Neighborhood Hits	998	Shared Neighborhood Hits	98
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MLL2_HUMAN
NC score	0.052623 (rank : 329)	θ value	0.125558 (rank : 82)
Query Neighborhood Hits	353	Target Neighborhood Hits	1788	Shared Neighborhood Hits	111
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ENAH_MOUSE
NC score	0.052538 (rank : 330)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	353	Target Neighborhood Hits	919	Shared Neighborhood Hits	70
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

TIF1A_HUMAN
NC score	0.052406 (rank : 331)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	353	Target Neighborhood Hits	327	Shared Neighborhood Hits	77
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

LRSM1_HUMAN
NC score	0.051697 (rank : 332)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	353	Target Neighborhood Hits	1078	Shared Neighborhood Hits	104
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MKRN1_HUMAN
NC score	0.051517 (rank : 333)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	353	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

YLPM1_MOUSE
NC score	0.051425 (rank : 334)	θ value	4.03905 (rank : 248)
Query Neighborhood Hits	353	Target Neighborhood Hits	505	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

NCOA6_HUMAN
NC score	0.051250 (rank : 335)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	353	Target Neighborhood Hits	1202	Shared Neighborhood Hits	91
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MKRN2_MOUSE
NC score	0.050638 (rank : 336)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	353	Target Neighborhood Hits	130	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

RGS3_MOUSE
NC score	0.050131 (rank : 337)	θ value	2.36792 (rank : 204)
Query Neighborhood Hits	353	Target Neighborhood Hits	1621	Shared Neighborhood Hits	122
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CS016_HUMAN
NC score	0.050050 (rank : 338)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	353	Target Neighborhood Hits	310	Shared Neighborhood Hits	47
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

BAT2_HUMAN
NC score	0.049915 (rank : 339)	θ value	3.0926 (rank : 217)
Query Neighborhood Hits	353	Target Neighborhood Hits	931	Shared Neighborhood Hits	84
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CN032_HUMAN
NC score	0.049766 (rank : 340)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

REPS1_HUMAN
NC score	0.049764 (rank : 341)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	353	Target Neighborhood Hits	205	Shared Neighborhood Hits	23
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

MKRN1_MOUSE
NC score	0.048340 (rank : 342)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	353	Target Neighborhood Hits	141	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

EP300_HUMAN
NC score	0.048220 (rank : 343)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	353	Target Neighborhood Hits	821	Shared Neighborhood Hits	68
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

AFF1_MOUSE
NC score	0.046867 (rank : 344)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	353	Target Neighborhood Hits	351	Shared Neighborhood Hits	37
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MUC1_HUMAN
NC score	0.046557 (rank : 345)	θ value	1.06291 (rank : 165)
Query Neighborhood Hits	353	Target Neighborhood Hits	975	Shared Neighborhood Hits	82
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

BSN_HUMAN
NC score	0.046432 (rank : 346)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	353	Target Neighborhood Hits	1537	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PRG4_HUMAN
NC score	0.046037 (rank : 347)	θ value	8.99809 (rank : 333)
Query Neighborhood Hits	353	Target Neighborhood Hits	764	Shared Neighborhood Hits	60
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MAGE1_HUMAN
NC score	0.044954 (rank : 348)	θ value	1.06291 (rank : 164)
Query Neighborhood Hits	353	Target Neighborhood Hits	1389	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

WASL_HUMAN
NC score	0.044911 (rank : 349)	θ value	0.813845 (rank : 158)
Query Neighborhood Hits	353	Target Neighborhood Hits	312	Shared Neighborhood Hits	36
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

HCN4_MOUSE
NC score	0.043883 (rank : 350)	θ value	0.0431538 (rank : 53)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

RTN4_MOUSE
NC score	0.043819 (rank : 351)	θ value	0.0148317 (rank : 40)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

RERE_MOUSE
NC score	0.043717 (rank : 352)	θ value	3.0926 (rank : 228)
Query Neighborhood Hits	353	Target Neighborhood Hits	785	Shared Neighborhood Hits	59
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

K1210_HUMAN
NC score	0.042213 (rank : 353)	θ value	0.813845 (rank : 146)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

RIN3_MOUSE
NC score	0.041980 (rank : 354)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	353	Target Neighborhood Hits	239	Shared Neighborhood Hits	30
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

REPS1_MOUSE
NC score	0.041909 (rank : 355)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

EFS_HUMAN
NC score	0.038716 (rank : 356)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	353	Target Neighborhood Hits	348	Shared Neighborhood Hits	33
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

TNC6B_HUMAN
NC score	0.038542 (rank : 357)	θ value	6.88961 (rank : 303)
Query Neighborhood Hits	353	Target Neighborhood Hits	256	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

PCLO_MOUSE
NC score	0.037987 (rank : 358)	θ value	6.88961 (rank : 296)
Query Neighborhood Hits	353	Target Neighborhood Hits	2275	Shared Neighborhood Hits	126
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SEPT9_HUMAN
NC score	0.037976 (rank : 359)	θ value	1.06291 (rank : 171)
Query Neighborhood Hits	353	Target Neighborhood Hits	706	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CEL_HUMAN
NC score	0.036611 (rank : 360)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	353	Target Neighborhood Hits	896	Shared Neighborhood Hits	78
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

AFF4_HUMAN
NC score	0.036501 (rank : 361)	θ value	0.365318 (rank : 109)
Query Neighborhood Hits	353	Target Neighborhood Hits	611	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

RIN3_HUMAN
NC score	0.035273 (rank : 362)	θ value	5.27518 (rank : 269)
Query Neighborhood Hits	353	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

TXND2_HUMAN
NC score	0.034760 (rank : 363)	θ value	5.27518 (rank : 281)
Query Neighborhood Hits	353	Target Neighborhood Hits	793	Shared Neighborhood Hits	59
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

K1802_HUMAN
NC score	0.034427 (rank : 364)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	353	Target Neighborhood Hits	1378	Shared Neighborhood Hits	94
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MNT_MOUSE
NC score	0.033222 (rank : 365)	θ value	8.99809 (rank : 329)
Query Neighborhood Hits	353	Target Neighborhood Hits	432	Shared Neighborhood Hits	46
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

GGA3_MOUSE
NC score	0.032997 (rank : 366)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	353	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

TF3C2_HUMAN
NC score	0.032944 (rank : 367)	θ value	6.88961 (rank : 300)
Query Neighborhood Hits	353	Target Neighborhood Hits	168	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

CSKI1_MOUSE
NC score	0.032881 (rank : 368)	θ value	0.125558 (rank : 79)
Query Neighborhood Hits	353	Target Neighborhood Hits	1031	Shared Neighborhood Hits	88
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CIC_HUMAN
NC score	0.032793 (rank : 369)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	353	Target Neighborhood Hits	992	Shared Neighborhood Hits	87
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BRD4_MOUSE
NC score	0.032775 (rank : 370)	θ value	0.47712 (rank : 119)
Query Neighborhood Hits	353	Target Neighborhood Hits	845	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

IRS2_HUMAN
NC score	0.031618 (rank : 371)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	353	Target Neighborhood Hits	262	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

AF9_HUMAN
NC score	0.031175 (rank : 372)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	353	Target Neighborhood Hits	202	Shared Neighborhood Hits	14
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

ATX2_HUMAN
NC score	0.031116 (rank : 373)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	353	Target Neighborhood Hits	375	Shared Neighborhood Hits	36
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

RAI1_MOUSE
NC score	0.031110 (rank : 374)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	353	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TPO_MOUSE
NC score	0.030388 (rank : 375)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	353	Target Neighborhood Hits	258	Shared Neighborhood Hits	39
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

AFF4_MOUSE
NC score	0.030381 (rank : 376)	θ value	6.88961 (rank : 282)
Query Neighborhood Hits	353	Target Neighborhood Hits	581	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

HCN4_HUMAN
NC score	0.029189 (rank : 377)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	353	Target Neighborhood Hits	303	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

CSKI1_HUMAN
NC score	0.028299 (rank : 378)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	353	Target Neighborhood Hits	997	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

IASPP_MOUSE
NC score	0.026660 (rank : 379)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	353	Target Neighborhood Hits	1024	Shared Neighborhood Hits	72
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

BAG3_HUMAN
NC score	0.025895 (rank : 380)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	353	Target Neighborhood Hits	314	Shared Neighborhood Hits	46
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

PO121_HUMAN
NC score	0.025826 (rank : 381)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	353	Target Neighborhood Hits	344	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SEPT9_MOUSE
NC score	0.025762 (rank : 382)	θ value	0.279714 (rank : 103)
Query Neighborhood Hits	353	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SCAP_HUMAN
NC score	0.025749 (rank : 383)	θ value	1.06291 (rank : 170)
Query Neighborhood Hits	353	Target Neighborhood Hits	368	Shared Neighborhood Hits	31
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

APXL_HUMAN
NC score	0.024978 (rank : 384)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	353	Target Neighborhood Hits	553	Shared Neighborhood Hits	43
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

K0310_HUMAN
NC score	0.024924 (rank : 385)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	353	Target Neighborhood Hits	420	Shared Neighborhood Hits	43
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

ZN438_HUMAN
NC score	0.024563 (rank : 386)	θ value	0.000786445 (rank : 13)
Query Neighborhood Hits	353	Target Neighborhood Hits	906	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

T240L_MOUSE
NC score	0.024333 (rank : 387)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	353	Target Neighborhood Hits	143	Shared Neighborhood Hits	19
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

NFAC4_HUMAN
NC score	0.023823 (rank : 388)	θ value	3.0926 (rank : 223)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	16
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

NFAC1_HUMAN
NC score	0.023735 (rank : 389)	θ value	8.99809 (rank : 331)
Query Neighborhood Hits	353	Target Neighborhood Hits	312	Shared Neighborhood Hits	37
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

DNMBP_MOUSE
NC score	0.023537 (rank : 390)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	353	Target Neighborhood Hits	435	Shared Neighborhood Hits	23
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ROBO4_MOUSE
NC score	0.023519 (rank : 391)	θ value	5.27518 (rank : 270)
Query Neighborhood Hits	353	Target Neighborhood Hits	358	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SOX13_HUMAN
NC score	0.023250 (rank : 392)	θ value	5.27518 (rank : 272)
Query Neighborhood Hits	353	Target Neighborhood Hits	464	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

IWS1_MOUSE
NC score	0.023205 (rank : 393)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	353	Target Neighborhood Hits	1258	Shared Neighborhood Hits	75
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

T240L_HUMAN
NC score	0.022510 (rank : 394)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	353	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

GAB1_HUMAN
NC score	0.021903 (rank : 395)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	353	Target Neighborhood Hits	279	Shared Neighborhood Hits	36
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

TENS4_MOUSE
NC score	0.021885 (rank : 396)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

ANR11_HUMAN
NC score	0.021198 (rank : 397)	θ value	1.81305 (rank : 188)
Query Neighborhood Hits	353	Target Neighborhood Hits	1289	Shared Neighborhood Hits	70
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

EPN1_HUMAN
NC score	0.020853 (rank : 398)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	353	Target Neighborhood Hits	206	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

ZO1_HUMAN
NC score	0.020619 (rank : 399)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	353	Target Neighborhood Hits	474	Shared Neighborhood Hits	42
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

FMNL_HUMAN
NC score	0.020539 (rank : 400)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	353	Target Neighborhood Hits	529	Shared Neighborhood Hits	47
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

CJ047_HUMAN
NC score	0.019857 (rank : 401)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	353	Target Neighborhood Hits	164	Shared Neighborhood Hits	18
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

DRAP1_MOUSE
NC score	0.019727 (rank : 402)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	353	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

SRTD3_MOUSE
NC score	0.019666 (rank : 403)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	353	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

STAP2_HUMAN
NC score	0.019508 (rank : 404)	θ value	5.27518 (rank : 273)
Query Neighborhood Hits	353	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGK3, Q9NXI2	Gene names	STAP2, BKS
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate).

RB6I2_MOUSE
NC score	0.019164 (rank : 405)	θ value	0.813845 (rank : 150)
Query Neighborhood Hits	353	Target Neighborhood Hits	1433	Shared Neighborhood Hits	51
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RB6I2_HUMAN
NC score	0.019008 (rank : 406)	θ value	0.813845 (rank : 149)
Query Neighborhood Hits	353	Target Neighborhood Hits	1584	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

IASPP_HUMAN
NC score	0.018515 (rank : 407)	θ value	3.0926 (rank : 221)
Query Neighborhood Hits	353	Target Neighborhood Hits	688	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

STAP2_MOUSE
NC score	0.018346 (rank : 408)	θ value	5.27518 (rank : 274)
Query Neighborhood Hits	353	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0L1, Q8BWS2	Gene names	Stap2
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2).

ATBF1_HUMAN
NC score	0.017610 (rank : 409)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	353	Target Neighborhood Hits	1547	Shared Neighborhood Hits	58
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

HAIR_HUMAN
NC score	0.017556 (rank : 410)	θ value	3.0926 (rank : 220)
Query Neighborhood Hits	353	Target Neighborhood Hits	172	Shared Neighborhood Hits	24
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

TENS4_HUMAN
NC score	0.016905 (rank : 411)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	353	Target Neighborhood Hits	214	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

BAG4_HUMAN
NC score	0.016815 (rank : 412)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	353	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

RNC_HUMAN
NC score	0.016783 (rank : 413)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	353	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

ZFHX2_HUMAN
NC score	0.016570 (rank : 414)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	353	Target Neighborhood Hits	1178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

MARH4_HUMAN
NC score	0.014714 (rank : 415)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	353	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2E8, Q86WR8	Gene names	MARCH4, KIAA1399, RNF174
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 4 (Membrane-associated RING-CH protein IV) (MARCH-IV) (RING finger protein 174).

SPEG_MOUSE
NC score	0.014362 (rank : 416)	θ value	0.62314 (rank : 139)
Query Neighborhood Hits	353	Target Neighborhood Hits	1959	Shared Neighborhood Hits	96
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PARP4_HUMAN
NC score	0.014220 (rank : 417)	θ value	6.88961 (rank : 295)
Query Neighborhood Hits	353	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

H2B2D_HUMAN
NC score	0.013818 (rank : 418)	θ value	1.06291 (rank : 162)
Query Neighborhood Hits	353	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DRA6	Gene names	HIST2H2BD
Domain Architecture	No domain graphic available
Description	Histone H2B type 2-D.

ZYX_HUMAN
NC score	0.013740 (rank : 419)	θ value	4.03905 (rank : 253)
Query Neighborhood Hits	353	Target Neighborhood Hits	387	Shared Neighborhood Hits	30
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

GFC1_HUMAN
NC score	0.013716 (rank : 420)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	353	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

GO45_MOUSE
NC score	0.013490 (rank : 421)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	353	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2X8, Q3TJC4, Q8C0U6, Q9DAV7	Gene names	Blzf1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1).

GCX1_HUMAN
NC score	0.013335 (rank : 422)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	353	Target Neighborhood Hits	132	Shared Neighborhood Hits	13
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

EVPL_MOUSE
NC score	0.013262 (rank : 423)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	353	Target Neighborhood Hits	952	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

PTN23_MOUSE
NC score	0.013081 (rank : 424)	θ value	8.99809 (rank : 334)
Query Neighborhood Hits	353	Target Neighborhood Hits	726	Shared Neighborhood Hits	60
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

K0494_MOUSE
NC score	0.013035 (rank : 425)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	353	Target Neighborhood Hits	241	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

GA2L1_MOUSE
NC score	0.012795 (rank : 426)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	353	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

FA48A_HUMAN
NC score	0.012591 (rank : 427)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	353	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

VINEX_HUMAN
NC score	0.012084 (rank : 428)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	353	Target Neighborhood Hits	270	Shared Neighborhood Hits	13
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

IRS1_HUMAN
NC score	0.012053 (rank : 429)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	353	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

CUTL2_HUMAN
NC score	0.011879 (rank : 430)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	353	Target Neighborhood Hits	906	Shared Neighborhood Hits	42
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MAST4_HUMAN
NC score	0.011486 (rank : 431)	θ value	0.813845 (rank : 147)
Query Neighborhood Hits	353	Target Neighborhood Hits	1804	Shared Neighborhood Hits	98
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

WNK4_HUMAN
NC score	0.011116 (rank : 432)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	353	Target Neighborhood Hits	1043	Shared Neighborhood Hits	41
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ABI3_HUMAN
NC score	0.011047 (rank : 433)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	353	Target Neighborhood Hits	227	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CEND3_MOUSE
NC score	0.011010 (rank : 434)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	353	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

KCNH2_MOUSE
NC score	0.010355 (rank : 435)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

B4GN4_HUMAN
NC score	0.009947 (rank : 436)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	353	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

TENX_HUMAN
NC score	0.009817 (rank : 437)	θ value	0.21417 (rank : 96)
Query Neighborhood Hits	353	Target Neighborhood Hits	789	Shared Neighborhood Hits	14
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

H2B2C_HUMAN
NC score	0.009776 (rank : 438)	θ value	5.27518 (rank : 258)
Query Neighborhood Hits	353	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DN03	Gene names	HIST2H2BC
Domain Architecture	No domain graphic available
Description	Histone H2B type 2-C (H2.t) (H2B/t).

ITSN2_HUMAN
NC score	0.009753 (rank : 439)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	353	Target Neighborhood Hits	1173	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

NFIB_MOUSE
NC score	0.009267 (rank : 440)	θ value	5.27518 (rank : 267)
Query Neighborhood Hits	353	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NAGS_HUMAN
NC score	0.009156 (rank : 441)	θ value	8.99809 (rank : 330)
Query Neighborhood Hits	353	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N159, Q8IWR4	Gene names	NAGS
Domain Architecture	No domain graphic available
Description	N-acetylglutamate synthase, mitochondrial precursor (EC 2.3.1.1) (Amino-acid acetyltransferase) [Contains: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form].

ADA29_HUMAN
NC score	0.009011 (rank : 442)	θ value	1.38821 (rank : 175)
Query Neighborhood Hits	353	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

SYNJ2_MOUSE
NC score	0.008537 (rank : 443)	θ value	6.88961 (rank : 299)
Query Neighborhood Hits	353	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

PLS4_MOUSE
NC score	0.008400 (rank : 444)	θ value	6.88961 (rank : 297)
Query Neighborhood Hits	353	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	P58196, Q3TMI2, Q8BH62	Gene names	Plscr4
Domain Architecture	No domain graphic available
Description	Phospholipid scramblase 4 (PL scramblase 4) (Ca(2+)-dependent phospholipid scramblase 4).

PO6F2_HUMAN
NC score	0.008336 (rank : 445)	θ value	8.99809 (rank : 332)
Query Neighborhood Hits	353	Target Neighborhood Hits	618	Shared Neighborhood Hits	39
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

NCOA1_MOUSE
NC score	0.008106 (rank : 446)	θ value	6.88961 (rank : 293)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	18
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

KCNB2_HUMAN
NC score	0.007772 (rank : 447)	θ value	1.06291 (rank : 163)
Query Neighborhood Hits	353	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

CD2L7_HUMAN
NC score	0.007321 (rank : 448)	θ value	0.813845 (rank : 145)
Query Neighborhood Hits	353	Target Neighborhood Hits	1275	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

TITIN_HUMAN
NC score	0.007162 (rank : 449)	θ value	0.47712 (rank : 124)
Query Neighborhood Hits	353	Target Neighborhood Hits	2923	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN575_HUMAN
NC score	0.006962 (rank : 450)	θ value	0.0148317 (rank : 44)
Query Neighborhood Hits	353	Target Neighborhood Hits	739	Shared Neighborhood Hits	23
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

HXA3_HUMAN
NC score	0.006467 (rank : 451)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	353	Target Neighborhood Hits	535	Shared Neighborhood Hits	31
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

LAMA3_MOUSE
NC score	0.006274 (rank : 452)	θ value	8.99809 (rank : 326)
Query Neighborhood Hits	353	Target Neighborhood Hits	859	Shared Neighborhood Hits	16
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

AAKG2_MOUSE
NC score	0.005771 (rank : 453)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	353	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

HXA3_MOUSE
NC score	0.005596 (rank : 454)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	353	Target Neighborhood Hits	558	Shared Neighborhood Hits	33
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

E2AK4_HUMAN
NC score	0.003772 (rank : 455)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	353	Target Neighborhood Hits	1012	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

ZN575_MOUSE
NC score	0.003731 (rank : 456)	θ value	0.279714 (rank : 108)
Query Neighborhood Hits	353	Target Neighborhood Hits	715	Shared Neighborhood Hits	20
SwissProt Accessions	Q3TXZ1	Gene names	Znf575, Zfp575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ATP7A_MOUSE
NC score	0.003627 (rank : 457)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	353	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q64430, O35101, P97422, Q64431	Gene names	Atp7a, Mnk
Domain Architecture
Description	Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein homolog).

WNK4_MOUSE
NC score	0.003425 (rank : 458)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	353	Target Neighborhood Hits	961	Shared Neighborhood Hits	33
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

GLIS1_MOUSE
NC score	0.002692 (rank : 459)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	353	Target Neighborhood Hits	751	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

SLIK4_MOUSE
NC score	0.002505 (rank : 460)	θ value	5.27518 (rank : 271)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	Q810B8, Q8BL56, Q8BWB0, Q8BYG4, Q8C056	Gene names	Slitrk4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

SUHW4_MOUSE
NC score	0.002352 (rank : 461)	θ value	5.27518 (rank : 275)
Query Neighborhood Hits	353	Target Neighborhood Hits	737	Shared Neighborhood Hits	19
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ZN668_HUMAN
NC score	-0.000033 (rank : 462)	θ value	0.365318 (rank : 118)
Query Neighborhood Hits	353	Target Neighborhood Hits	761	Shared Neighborhood Hits	19
SwissProt Accessions	Q96K58, Q59EV1, Q8N669, Q9H8L4	Gene names	ZNF668
Domain Architecture	No domain graphic available
Description	Zinc finger protein 668.

E2AK3_HUMAN
NC score	-0.000417 (rank : 463)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	353	Target Neighborhood Hits	859	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

ZN668_MOUSE
NC score	-0.000808 (rank : 464)	θ value	4.03905 (rank : 252)
Query Neighborhood Hits	353	Target Neighborhood Hits	763	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K2R5, Q3TEM2, Q3U7Y5, Q8C8B7	Gene names	Znf668, Zfp668
Domain Architecture	No domain graphic available
Description	Zinc finger protein 668.

LUM_HUMAN
NC score	-0.000973 (rank : 465)	θ value	8.99809 (rank : 327)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	P51884, Q96QM7	Gene names	LUM, LDC
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

TTK_MOUSE
NC score	-0.001067 (rank : 466)	θ value	4.03905 (rank : 246)
Query Neighborhood Hits	353	Target Neighborhood Hits	803	Shared Neighborhood Hits	9
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

ZFP92_MOUSE
NC score	-0.002076 (rank : 467)	θ value	4.03905 (rank : 249)
Query Neighborhood Hits	353	Target Neighborhood Hits	731	Shared Neighborhood Hits	13
SwissProt Accessions	Q62396	Gene names	Zfp92
Domain Architecture
Description	Zinc finger protein 92 (Zfp-92).

SRMS_MOUSE
NC score	-0.002118 (rank : 468)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	353	Target Neighborhood Hits	964	Shared Neighborhood Hits	18
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

V1BR_HUMAN
NC score	-0.002801 (rank : 469)	θ value	4.03905 (rank : 247)
Query Neighborhood Hits	353	Target Neighborhood Hits	895	Shared Neighborhood Hits	3
SwissProt Accessions	P47901, Q5TZ00	Gene names	AVPR1B, AVPR3, VPR3
Domain Architecture
Description	Vasopressin V1b receptor (V1bR) (AVPR V1b) (Vasopressin V3 receptor) (AVPR V3) (Antidiuretic hormone receptor 1b).

V1BR_MOUSE
NC score	-0.004187 (rank : 470)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	353	Target Neighborhood Hits	895	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU02	Gene names	Avpr1b, V1br
Domain Architecture
Description	Vasopressin V1b receptor (V1bR) (AVPR V1b) (Vasopressin V3 receptor) (AVPR V3) (Antidiuretic hormone receptor 1b).