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Network neighborhood for query Sequence : CGRF1_HUMAN

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CGRF1_HUMAN
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CGRF1_HUMAN
θ value	8.26266e-179 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
θ value	5.94893e-161 (rank : 2)	NC score	0.992282 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

RNF26_HUMAN
θ value	5.81887e-07 (rank : 3)	NC score	0.512978 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	95	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

MGRN1_HUMAN
θ value	8.40245e-06 (rank : 4)	NC score	0.377832 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	192	Shared Neighborhood Hits	40
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

RNF34_HUMAN
θ value	1.43324e-05 (rank : 5)	NC score	0.441943 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	153	Shared Neighborhood Hits	39
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	1.43324e-05 (rank : 6)	NC score	0.443009 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	160	Shared Neighborhood Hits	40
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RFFL_HUMAN
θ value	0.000158464 (rank : 7)	NC score	0.419365 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	0.000158464 (rank : 8)	NC score	0.425790 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	145	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

LRSM1_MOUSE
θ value	0.000270298 (rank : 9)	NC score	0.195649 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	874	Shared Neighborhood Hits	38
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MYLIP_HUMAN
θ value	0.000270298 (rank : 10)	NC score	0.231318 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	162	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

BIRC2_HUMAN
θ value	0.00035302 (rank : 11)	NC score	0.332593 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	142	Shared Neighborhood Hits	38
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

MIB1_HUMAN
θ value	0.000461057 (rank : 12)	NC score	0.151003 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	470	Shared Neighborhood Hits	38
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

BIRC8_HUMAN
θ value	0.000602161 (rank : 13)	NC score	0.346818 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

LRSM1_HUMAN
θ value	0.000602161 (rank : 14)	NC score	0.175265 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	1078	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MGRN1_MOUSE
θ value	0.000786445 (rank : 15)	NC score	0.370835 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MYLIP_MOUSE
θ value	0.000786445 (rank : 16)	NC score	0.210203 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	139	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MIB1_MOUSE
θ value	0.00102713 (rank : 17)	NC score	0.150537 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	471	Shared Neighborhood Hits	38
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

BIRC2_MOUSE
θ value	0.00175202 (rank : 18)	NC score	0.328329 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	0.00228821 (rank : 19)	NC score	0.330051 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	133	Shared Neighborhood Hits	37
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	0.00390308 (rank : 20)	NC score	0.328127 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

NEUL1_HUMAN
θ value	0.00390308 (rank : 21)	NC score	0.327816 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	114	Shared Neighborhood Hits	37
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	0.00390308 (rank : 22)	NC score	0.331589 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	106	Shared Neighborhood Hits	37
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

RKHD1_HUMAN
θ value	0.0193708 (rank : 23)	NC score	0.323861 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

BIRC4_HUMAN
θ value	0.0252991 (rank : 24)	NC score	0.301148 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	89	Shared Neighborhood Hits	33
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	0.0330416 (rank : 25)	NC score	0.298586 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC7_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.315759 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	185	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

RNF8_MOUSE
θ value	0.0961366 (rank : 27)	NC score	0.130983 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	618	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RN146_HUMAN
θ value	0.125558 (rank : 28)	NC score	0.153303 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	0.125558 (rank : 29)	NC score	0.152315 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

MIB2_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.127673 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	438	Shared Neighborhood Hits	41
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

DTX3_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.072138 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

MIB2_MOUSE
θ value	0.62314 (rank : 32)	NC score	0.123897 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	409	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

RNF8_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.119416 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	622	Shared Neighborhood Hits	43
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

ZC3H5_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.110754 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

DTX3_MOUSE
θ value	0.813845 (rank : 35)	NC score	0.071524 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

DTX3L_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.075026 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	187	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

ZC3H5_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.110752 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

RBBP6_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.043021 (rank : 71)
Query Neighborhood Hits	51	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.047851 (rank : 69)
Query Neighborhood Hits	51	Target Neighborhood Hits	1014	Shared Neighborhood Hits	25
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RN168_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.088867 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	370	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRIM2_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.038726 (rank : 73)
Query Neighborhood Hits	51	Target Neighborhood Hits	330	Shared Neighborhood Hits	28
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.038205 (rank : 74)
Query Neighborhood Hits	51	Target Neighborhood Hits	331	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

CEAM8_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.006590 (rank : 78)
Query Neighborhood Hits	51	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

RN168_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.073731 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	440	Shared Neighborhood Hits	34
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SMRA3_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.046809 (rank : 70)
Query Neighborhood Hits	51	Target Neighborhood Hits	267	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SSPO_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.006404 (rank : 79)
Query Neighborhood Hits	51	Target Neighborhood Hits	800	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TRI12_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.040311 (rank : 72)
Query Neighborhood Hits	51	Target Neighborhood Hits	387	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI42_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.028679 (rank : 76)
Query Neighborhood Hits	51	Target Neighborhood Hits	283	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.035060 (rank : 75)
Query Neighborhood Hits	51	Target Neighborhood Hits	316	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI65_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.053955 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	340	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

MICA1_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.006780 (rank : 77)
Query Neighborhood Hits	51	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

BIR1A_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.076785 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.077748 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1E_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.078418 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.078110 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.078015 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.078956 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIRC5_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.088795 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

BIRC5_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.094638 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC6_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.058260 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

CBLB_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.056698 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	261	Shared Neighborhood Hits	33
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.057419 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.057969 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	173	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.060445 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	186	Shared Neighborhood Hits	32
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.057891 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	353	Shared Neighborhood Hits	31
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.056529 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	426	Shared Neighborhood Hits	33
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CHFR_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.052003 (rank : 67)
Query Neighborhood Hits	51	Target Neighborhood Hits	255	Shared Neighborhood Hits	27
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.053345 (rank : 66)
Query Neighborhood Hits	51	Target Neighborhood Hits	264	Shared Neighborhood Hits	29
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

MDM2_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.082422 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MDM2_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.069316 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	22
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

MDM4_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.086097 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

PEX10_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.081927 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN141_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.065106 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	199	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.064631 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	200	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN185_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.067935 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.066789 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	211	Shared Neighborhood Hits	34
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TOPRS_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.050289 (rank : 68)
Query Neighborhood Hits	51	Target Neighborhood Hits	263	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI26_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.053380 (rank : 65)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	43
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.054951 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

Hits sorted by NC score

CGRF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.26266e-179 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
NC score	0.992282 (rank : 2)	θ value	5.94893e-161 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

RNF26_HUMAN
NC score	0.512978 (rank : 3)	θ value	5.81887e-07 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	95	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF34_MOUSE
NC score	0.443009 (rank : 4)	θ value	1.43324e-05 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	160	Shared Neighborhood Hits	40
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.441943 (rank : 5)	θ value	1.43324e-05 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	153	Shared Neighborhood Hits	39
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RFFL_MOUSE
NC score	0.425790 (rank : 6)	θ value	0.000158464 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	145	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
NC score	0.419365 (rank : 7)	θ value	0.000158464 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

MGRN1_HUMAN
NC score	0.377832 (rank : 8)	θ value	8.40245e-06 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	192	Shared Neighborhood Hits	40
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
NC score	0.370835 (rank : 9)	θ value	0.000786445 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

BIRC8_HUMAN
NC score	0.346818 (rank : 10)	θ value	0.000602161 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BIRC2_HUMAN
NC score	0.332593 (rank : 11)	θ value	0.00035302 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	142	Shared Neighborhood Hits	38
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

NEURL_MOUSE
NC score	0.331589 (rank : 12)	θ value	0.00390308 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	106	Shared Neighborhood Hits	37
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

BIRC3_HUMAN
NC score	0.330051 (rank : 13)	θ value	0.00228821 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	133	Shared Neighborhood Hits	37
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC2_MOUSE
NC score	0.328329 (rank : 14)	θ value	0.00175202 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_MOUSE
NC score	0.328127 (rank : 15)	θ value	0.00390308 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

NEUL1_HUMAN
NC score	0.327816 (rank : 16)	θ value	0.00390308 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	114	Shared Neighborhood Hits	37
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

RKHD1_HUMAN
NC score	0.323861 (rank : 17)	θ value	0.0193708 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

BIRC7_HUMAN
NC score	0.315759 (rank : 18)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	185	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC4_HUMAN
NC score	0.301148 (rank : 19)	θ value	0.0252991 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	89	Shared Neighborhood Hits	33
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
NC score	0.298586 (rank : 20)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

MYLIP_HUMAN
NC score	0.231318 (rank : 21)	θ value	0.000270298 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	162	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_MOUSE
NC score	0.210203 (rank : 22)	θ value	0.000786445 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	139	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

LRSM1_MOUSE
NC score	0.195649 (rank : 23)	θ value	0.000270298 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	874	Shared Neighborhood Hits	38
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

LRSM1_HUMAN
NC score	0.175265 (rank : 24)	θ value	0.000602161 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	1078	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

RN146_HUMAN
NC score	0.153303 (rank : 25)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.152315 (rank : 26)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

MIB1_HUMAN
NC score	0.151003 (rank : 27)	θ value	0.000461057 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	470	Shared Neighborhood Hits	38
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.150537 (rank : 28)	θ value	0.00102713 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	471	Shared Neighborhood Hits	38
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RNF8_MOUSE
NC score	0.130983 (rank : 29)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	618	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

MIB2_HUMAN
NC score	0.127673 (rank : 30)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	438	Shared Neighborhood Hits	41
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
NC score	0.123897 (rank : 31)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	409	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

RNF8_HUMAN
NC score	0.119416 (rank : 32)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	622	Shared Neighborhood Hits	43
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

ZC3H5_MOUSE
NC score	0.110754 (rank : 33)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

ZC3H5_HUMAN
NC score	0.110752 (rank : 34)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

BIRC5_MOUSE
NC score	0.094638 (rank : 35)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

RN168_HUMAN
NC score	0.088867 (rank : 36)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	370	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

BIRC5_HUMAN
NC score	0.088795 (rank : 37)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

MDM4_HUMAN
NC score	0.086097 (rank : 38)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MDM2_HUMAN
NC score	0.082422 (rank : 39)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	51	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

PEX10_HUMAN
NC score	0.081927 (rank : 40)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	51	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

BIRC1_HUMAN
NC score	0.078956 (rank : 41)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1E_MOUSE
NC score	0.078418 (rank : 42)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
NC score	0.078110 (rank : 43)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
NC score	0.078015 (rank : 44)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1B_MOUSE
NC score	0.077748 (rank : 45)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1A_MOUSE
NC score	0.076785 (rank : 46)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

DTX3L_HUMAN
NC score	0.075026 (rank : 47)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	187	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RN168_MOUSE
NC score	0.073731 (rank : 48)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	440	Shared Neighborhood Hits	34
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

DTX3_HUMAN
NC score	0.072138 (rank : 49)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
NC score	0.071524 (rank : 50)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

MDM2_MOUSE
NC score	0.069316 (rank : 51)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	22
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

RN185_HUMAN
NC score	0.067935 (rank : 52)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	51	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.066789 (rank : 53)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	51	Target Neighborhood Hits	211	Shared Neighborhood Hits	34
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN141_HUMAN
NC score	0.065106 (rank : 54)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	51	Target Neighborhood Hits	199	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.064631 (rank : 55)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	51	Target Neighborhood Hits	200	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

CBLC_MOUSE
NC score	0.060445 (rank : 56)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	186	Shared Neighborhood Hits	32
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

BIRC6_HUMAN
NC score	0.058260 (rank : 57)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

CBLC_HUMAN
NC score	0.057969 (rank : 58)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	173	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBL_HUMAN
NC score	0.057891 (rank : 59)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	51	Target Neighborhood Hits	353	Shared Neighborhood Hits	31
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBLB_MOUSE
NC score	0.057419 (rank : 60)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.056698 (rank : 61)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	261	Shared Neighborhood Hits	33
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBL_MOUSE
NC score	0.056529 (rank : 62)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	51	Target Neighborhood Hits	426	Shared Neighborhood Hits	33
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TRI26_MOUSE
NC score	0.054951 (rank : 63)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	51	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI65_MOUSE
NC score	0.053955 (rank : 64)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	340	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI26_HUMAN
NC score	0.053380 (rank : 65)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	43
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

CHFR_MOUSE
NC score	0.053345 (rank : 66)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	51	Target Neighborhood Hits	264	Shared Neighborhood Hits	29
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_HUMAN
NC score	0.052003 (rank : 67)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	51	Target Neighborhood Hits	255	Shared Neighborhood Hits	27
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TOPRS_MOUSE
NC score	0.050289 (rank : 68)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	51	Target Neighborhood Hits	263	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RBBP6_MOUSE
NC score	0.047851 (rank : 69)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	1014	Shared Neighborhood Hits	25
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SMRA3_MOUSE
NC score	0.046809 (rank : 70)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	267	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RBBP6_HUMAN
NC score	0.043021 (rank : 71)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRI12_MOUSE
NC score	0.040311 (rank : 72)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	387	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM2_HUMAN
NC score	0.038726 (rank : 73)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	330	Shared Neighborhood Hits	28
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.038205 (rank : 74)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	331	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI42_MOUSE
NC score	0.035060 (rank : 75)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	316	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_HUMAN
NC score	0.028679 (rank : 76)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	283	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

MICA1_HUMAN
NC score	0.006780 (rank : 77)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

CEAM8_HUMAN
NC score	0.006590 (rank : 78)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

SSPO_MOUSE
NC score	0.006404 (rank : 79)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	800	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.