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Network neighborhood for query Sequence : RKHD1_HUMAN

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RKHD1_HUMAN
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RKHD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

FUBP1_HUMAN
θ value	6.43352e-06 (rank : 2)	NC score	0.370467 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	136	Shared Neighborhood Hits	30
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	6.43352e-06 (rank : 3)	NC score	0.370014 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	144	Shared Neighborhood Hits	31
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP3_HUMAN
θ value	7.1131e-05 (rank : 4)	NC score	0.368053 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	68	Shared Neighborhood Hits	28
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

NEUL1_HUMAN
θ value	0.000121331 (rank : 5)	NC score	0.365867 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

MYLIP_HUMAN
θ value	0.000158464 (rank : 6)	NC score	0.243832 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

BIRC3_HUMAN
θ value	0.00035302 (rank : 7)	NC score	0.354676 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

RFFL_HUMAN
θ value	0.00035302 (rank : 8)	NC score	0.411443 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	0.00035302 (rank : 9)	NC score	0.417222 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RNF34_HUMAN
θ value	0.00035302 (rank : 10)	NC score	0.418223 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	63
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	0.00035302 (rank : 11)	NC score	0.418432 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	160	Shared Neighborhood Hits	63
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

MYLIP_MOUSE
θ value	0.000461057 (rank : 12)	NC score	0.218769 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	139	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

VIGLN_MOUSE
θ value	0.000786445 (rank : 13)	NC score	0.268073 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

BIRC3_MOUSE
θ value	0.00102713 (rank : 14)	NC score	0.351850 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

NEURL_MOUSE
θ value	0.00102713 (rank : 15)	NC score	0.361027 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

BIRC2_HUMAN
θ value	0.00175202 (rank : 16)	NC score	0.348222 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	142	Shared Neighborhood Hits	65
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	0.00175202 (rank : 17)	NC score	0.346872 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

TDRKH_MOUSE
θ value	0.00228821 (rank : 18)	NC score	0.272248 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

RN169_HUMAN
θ value	0.00298849 (rank : 19)	NC score	0.252818 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	203	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

BIRC7_HUMAN
θ value	0.00390308 (rank : 20)	NC score	0.382198 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	185	Shared Neighborhood Hits	73
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

IASPP_MOUSE
θ value	0.00509761 (rank : 21)	NC score	0.059370 (rank : 260)
Query Neighborhood Hits	163	Target Neighborhood Hits	1024	Shared Neighborhood Hits	20
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ZN313_MOUSE
θ value	0.00509761 (rank : 22)	NC score	0.236034 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TDRKH_HUMAN
θ value	0.00665767 (rank : 23)	NC score	0.268347 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

FUBP2_HUMAN
θ value	0.00869519 (rank : 24)	NC score	0.346341 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

LRSM1_HUMAN
θ value	0.00869519 (rank : 25)	NC score	0.158986 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	1078	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LRSM1_MOUSE
θ value	0.00869519 (rank : 26)	NC score	0.176228 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	874	Shared Neighborhood Hits	64
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

PEX10_HUMAN
θ value	0.00869519 (rank : 27)	NC score	0.273212 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	81
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PCBP3_HUMAN
θ value	0.0113563 (rank : 28)	NC score	0.243664 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_MOUSE
θ value	0.0113563 (rank : 29)	NC score	0.243780 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

VIGLN_HUMAN
θ value	0.0113563 (rank : 30)	NC score	0.258870 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	71	Shared Neighborhood Hits	22
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

CGRF1_HUMAN
θ value	0.0193708 (rank : 31)	NC score	0.323861 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
θ value	0.0193708 (rank : 32)	NC score	0.319017 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

BIRC4_HUMAN
θ value	0.0431538 (rank : 33)	NC score	0.303027 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	0.0431538 (rank : 34)	NC score	0.300362 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	89	Shared Neighborhood Hits	49
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

IF2B2_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.264400 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
θ value	0.0431538 (rank : 36)	NC score	0.258691 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	148	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

MGRN1_HUMAN
θ value	0.0431538 (rank : 37)	NC score	0.285337 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

TRI27_MOUSE
θ value	0.0736092 (rank : 38)	NC score	0.137662 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	261	Shared Neighborhood Hits	81
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

NOVA2_HUMAN
θ value	0.0961366 (rank : 39)	NC score	0.284761 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

RNF26_HUMAN
θ value	0.0961366 (rank : 40)	NC score	0.342468 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	95	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

OGFR_HUMAN
θ value	0.125558 (rank : 41)	NC score	0.051273 (rank : 280)
Query Neighborhood Hits	163	Target Neighborhood Hits	1582	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PCBP4_HUMAN
θ value	0.125558 (rank : 42)	NC score	0.238595 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

NACAM_MOUSE
θ value	0.163984 (rank : 43)	NC score	0.040785 (rank : 290)
Query Neighborhood Hits	163	Target Neighborhood Hits	1866	Shared Neighborhood Hits	27
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TRI18_MOUSE
θ value	0.163984 (rank : 44)	NC score	0.131730 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI26_HUMAN
θ value	0.163984 (rank : 45)	NC score	0.174496 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	335	Shared Neighborhood Hits	89
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

ZN313_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.222198 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

MGRN1_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.282108 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MIB1_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.125821 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	470	Shared Neighborhood Hits	60
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.21417 (rank : 49)	NC score	0.126860 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	471	Shared Neighborhood Hits	59
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

PCBP1_HUMAN
θ value	0.21417 (rank : 50)	NC score	0.235521 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
θ value	0.21417 (rank : 51)	NC score	0.235521 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

RN125_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.220428 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	230	Shared Neighborhood Hits	70
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI11_MOUSE
θ value	0.21417 (rank : 53)	NC score	0.137207 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	329	Shared Neighborhood Hits	78
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI27_HUMAN
θ value	0.21417 (rank : 54)	NC score	0.131292 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	80
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI11_HUMAN
θ value	0.279714 (rank : 55)	NC score	0.135283 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	316	Shared Neighborhood Hits	77
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

MIB2_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.117239 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	438	Shared Neighborhood Hits	53
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

RN103_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.121247 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	43
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	0.365318 (rank : 58)	NC score	0.117750 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

SMRA3_HUMAN
θ value	0.365318 (rank : 59)	NC score	0.110680 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	265	Shared Neighborhood Hits	74
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI35_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.155408 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

CBLB_HUMAN
θ value	0.47712 (rank : 61)	NC score	0.204785 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	261	Shared Neighborhood Hits	77
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0.47712 (rank : 62)	NC score	0.205662 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	277	Shared Neighborhood Hits	79
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBL_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.207311 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	353	Shared Neighborhood Hits	79
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.47712 (rank : 64)	NC score	0.204028 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	426	Shared Neighborhood Hits	83
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CO8A2_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.039638 (rank : 293)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

DDX53_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.038493 (rank : 294)
Query Neighborhood Hits	163	Target Neighborhood Hits	124	Shared Neighborhood Hits	21
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

MIB2_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.113302 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	409	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PCBP4_MOUSE
θ value	0.47712 (rank : 68)	NC score	0.235121 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

RN166_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.198356 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	65
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	0.47712 (rank : 70)	NC score	0.197310 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	248	Shared Neighborhood Hits	67
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI43_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.141041 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	341	Shared Neighborhood Hits	81
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

BIRC8_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.331233 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CBLC_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.212110 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	186	Shared Neighborhood Hits	71
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CO8A2_HUMAN
θ value	0.62314 (rank : 74)	NC score	0.040882 (rank : 289)
Query Neighborhood Hits	163	Target Neighborhood Hits	299	Shared Neighborhood Hits	12
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

RNF8_MOUSE
θ value	0.62314 (rank : 75)	NC score	0.182560 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	618	Shared Neighborhood Hits	84
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RO52_MOUSE
θ value	0.62314 (rank : 76)	NC score	0.146242 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	360	Shared Neighborhood Hits	87
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

CBLC_HUMAN
θ value	0.813845 (rank : 77)	NC score	0.208708 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	173	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CM007_MOUSE
θ value	0.813845 (rank : 78)	NC score	0.113354 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	416	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

NOVA1_HUMAN
θ value	0.813845 (rank : 79)	NC score	0.252312 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

RNF8_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.180636 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	622	Shared Neighborhood Hits	84
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

CM007_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.104574 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	422	Shared Neighborhood Hits	42
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CO4A2_MOUSE
θ value	1.06291 (rank : 82)	NC score	0.033167 (rank : 298)
Query Neighborhood Hits	163	Target Neighborhood Hits	492	Shared Neighborhood Hits	18
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COCA1_HUMAN
θ value	1.06291 (rank : 83)	NC score	0.026345 (rank : 304)
Query Neighborhood Hits	163	Target Neighborhood Hits	458	Shared Neighborhood Hits	8
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

PO121_MOUSE
θ value	1.06291 (rank : 84)	NC score	0.042770 (rank : 288)
Query Neighborhood Hits	163	Target Neighborhood Hits	345	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RO52_HUMAN
θ value	1.06291 (rank : 85)	NC score	0.150692 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	419	Shared Neighborhood Hits	89
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

SF01_MOUSE
θ value	1.06291 (rank : 86)	NC score	0.076873 (rank : 210)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	16
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

TRI56_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.149525 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	339	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI65_MOUSE
θ value	1.06291 (rank : 88)	NC score	0.165399 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	340	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ARD1_MOUSE
θ value	1.38821 (rank : 89)	NC score	0.036183 (rank : 296)
Query Neighborhood Hits	163	Target Neighborhood Hits	573	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

BFAR_MOUSE
θ value	1.38821 (rank : 90)	NC score	0.160722 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	232	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

DBPA_MOUSE
θ value	1.38821 (rank : 91)	NC score	0.036509 (rank : 295)
Query Neighborhood Hits	163	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKB3, Q80WG4, Q9EQF7, Q9EQF8	Gene names	Csda, Msy4, Ybx3
Domain Architecture	No domain graphic available
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Y-box protein 3).

DCDC2_HUMAN
θ value	1.38821 (rank : 92)	NC score	0.034448 (rank : 297)
Query Neighborhood Hits	163	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

RN168_MOUSE
θ value	1.38821 (rank : 93)	NC score	0.184131 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	440	Shared Neighborhood Hits	80
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SF01_HUMAN
θ value	1.38821 (rank : 94)	NC score	0.075194 (rank : 214)
Query Neighborhood Hits	163	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

TIP60_HUMAN
θ value	1.38821 (rank : 95)	NC score	0.040267 (rank : 291)
Query Neighborhood Hits	163	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
θ value	1.38821 (rank : 96)	NC score	0.040237 (rank : 292)
Query Neighborhood Hits	163	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TOPRS_MOUSE
θ value	1.38821 (rank : 97)	NC score	0.122682 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	263	Shared Neighborhood Hits	52
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI18_HUMAN
θ value	1.38821 (rank : 98)	NC score	0.125345 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	67
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

PNPT1_HUMAN
θ value	1.81305 (rank : 99)	NC score	0.048896 (rank : 285)
Query Neighborhood Hits	163	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

TRI37_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.131262 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	56
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	1.81305 (rank : 101)	NC score	0.131175 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	316	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI39_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.130807 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	693	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	1.81305 (rank : 103)	NC score	0.129545 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	691	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM1_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.123784 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	345	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.123132 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	361	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

RN125_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.192996 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	220	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

SAM68_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.096537 (rank : 180)
Query Neighborhood Hits	163	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_MOUSE
θ value	2.36792 (rank : 108)	NC score	0.096207 (rank : 183)
Query Neighborhood Hits	163	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

TRI46_HUMAN
θ value	2.36792 (rank : 109)	NC score	0.111521 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	291	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.110785 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	287	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

UHRF1_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.106094 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	278	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.127282 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	269	Shared Neighborhood Hits	58
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	2.36792 (rank : 113)	NC score	0.128729 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	275	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZDHC5_HUMAN
θ value	2.36792 (rank : 114)	NC score	0.017301 (rank : 314)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

AMFR2_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.117202 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.119576 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	208	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ANKZ1_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.032857 (rank : 299)
Query Neighborhood Hits	163	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

COCA1_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.024602 (rank : 307)
Query Neighborhood Hits	163	Target Neighborhood Hits	467	Shared Neighborhood Hits	9
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

HRB2_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.050570 (rank : 282)
Query Neighborhood Hits	163	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q13601, Q8NEA8, Q8TC37, Q96AT5	Gene names	HRB2
Domain Architecture	No domain graphic available
Description	HIV-1 Rev-binding protein 2 (Rev-interacting protein 1) (Rip-1).

RBBP6_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.062815 (rank : 251)
Query Neighborhood Hits	163	Target Neighborhood Hits	1135	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	3.0926 (rank : 121)	NC score	0.069682 (rank : 226)
Query Neighborhood Hits	163	Target Neighborhood Hits	1014	Shared Neighborhood Hits	59
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RN168_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.199154 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	370	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI56_MOUSE
θ value	3.0926 (rank : 123)	NC score	0.136207 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	72
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

CA104_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.046606 (rank : 286)
Query Neighborhood Hits	163	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q66K80, Q8NA07	Gene names	C1orf104
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf104.

HRB2_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.049188 (rank : 284)
Query Neighborhood Hits	163	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGA5, Q8C029	Gene names	Hrb2
Domain Architecture	No domain graphic available
Description	HIV-1 Rev-binding protein 2 homolog.

M3K12_MOUSE
θ value	4.03905 (rank : 126)	NC score	-0.001386 (rank : 327)
Query Neighborhood Hits	163	Target Neighborhood Hits	957	Shared Neighborhood Hits	5
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MAML2_HUMAN
θ value	4.03905 (rank : 127)	NC score	0.030825 (rank : 301)
Query Neighborhood Hits	163	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MUC5B_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.024102 (rank : 308)
Query Neighborhood Hits	163	Target Neighborhood Hits	1020	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TRI35_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.148160 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	465	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

UHRF1_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.101115 (rank : 169)
Query Neighborhood Hits	163	Target Neighborhood Hits	272	Shared Neighborhood Hits	58
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

EMID2_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.023328 (rank : 309)
Query Neighborhood Hits	163	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

SENP3_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.018246 (rank : 313)
Query Neighborhood Hits	163	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SEPT9_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.011026 (rank : 316)
Query Neighborhood Hits	163	Target Neighborhood Hits	706	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TRI25_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.144305 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	446	Shared Neighborhood Hits	78
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

AATK_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.002873 (rank : 325)
Query Neighborhood Hits	163	Target Neighborhood Hits	1243	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CSKI1_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.022953 (rank : 310)
Query Neighborhood Hits	163	Target Neighborhood Hits	1031	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FGD5_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.019376 (rank : 312)
Query Neighborhood Hits	163	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

KCNQ4_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.008413 (rank : 322)
Query Neighborhood Hits	163	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

M3K12_HUMAN
θ value	6.88961 (rank : 139)	NC score	-0.001954 (rank : 328)
Query Neighborhood Hits	163	Target Neighborhood Hits	940	Shared Neighborhood Hits	6
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

TAF3_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.021818 (rank : 311)
Query Neighborhood Hits	163	Target Neighborhood Hits	568	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TOPRS_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.113370 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	286	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF3_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.057101 (rank : 272)
Query Neighborhood Hits	163	Target Neighborhood Hits	463	Shared Neighborhood Hits	44
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.059640 (rank : 258)
Query Neighborhood Hits	163	Target Neighborhood Hits	476	Shared Neighborhood Hits	48
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF6_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.091982 (rank : 190)
Query Neighborhood Hits	163	Target Neighborhood Hits	267	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.093275 (rank : 188)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	60
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI47_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.139998 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	286	Shared Neighborhood Hits	72
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.141757 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	295	Shared Neighborhood Hits	75
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

URFB1_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.025560 (rank : 305)
Query Neighborhood Hits	163	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

ASCC1_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.030231 (rank : 302)
Query Neighborhood Hits	163	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D8Z1, Q3TAC2	Gene names	Ascc1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50).

BBX_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.010048 (rank : 319)
Query Neighborhood Hits	163	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BFAR_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.153172 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	222	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

CRX_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.002447 (rank : 326)
Query Neighborhood Hits	163	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

DDX43_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.028265 (rank : 303)
Query Neighborhood Hits	163	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

FGD5_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.016686 (rank : 315)
Query Neighborhood Hits	163	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FXR2_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.042977 (rank : 287)
Query Neighborhood Hits	163	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

HXA13_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.003499 (rank : 324)
Query Neighborhood Hits	163	Target Neighborhood Hits	353	Shared Neighborhood Hits	4
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

MT4_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.024783 (rank : 306)
Query Neighborhood Hits	163	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NLGN2_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.010374 (rank : 317)
Query Neighborhood Hits	163	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.010215 (rank : 318)
Query Neighborhood Hits	163	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

OST4_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.006445 (rank : 323)
Query Neighborhood Hits	163	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

PEX2_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.031964 (rank : 300)
Query Neighborhood Hits	163	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

TNR3_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.009641 (rank : 321)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

ZAN_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.009689 (rank : 320)
Query Neighborhood Hits	163	Target Neighborhood Hits	808	Shared Neighborhood Hits	8
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

AKAP1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.068484 (rank : 230)
Query Neighborhood Hits	163	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.066783 (rank : 239)
Query Neighborhood Hits	163	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

BIR1A_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.084046 (rank : 200)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.085471 (rank : 198)
Query Neighborhood Hits	163	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1E_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.086215 (rank : 194)
Query Neighborhood Hits	163	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.085972 (rank : 195)
Query Neighborhood Hits	163	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.085837 (rank : 197)
Query Neighborhood Hits	163	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.086911 (rank : 193)
Query Neighborhood Hits	163	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIRC5_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.095937 (rank : 186)
Query Neighborhood Hits	163	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

BIRC5_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.103208 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC6_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.063328 (rank : 249)
Query Neighborhood Hits	163	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

BRCA1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.103870 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	381	Shared Neighborhood Hits	68
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.107826 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	436	Shared Neighborhood Hits	70
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BSPRY_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.078509 (rank : 206)
Query Neighborhood Hits	163	Target Neighborhood Hits	115	Shared Neighborhood Hits	24
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.078852 (rank : 205)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.065414 (rank : 242)
Query Neighborhood Hits	163	Target Neighborhood Hits	322	Shared Neighborhood Hits	22
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.065783 (rank : 240)
Query Neighborhood Hits	163	Target Neighborhood Hits	252	Shared Neighborhood Hits	22
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.061055 (rank : 254)
Query Neighborhood Hits	163	Target Neighborhood Hits	185	Shared Neighborhood Hits	20
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.064670 (rank : 245)
Query Neighborhood Hits	163	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.062539 (rank : 252)
Query Neighborhood Hits	163	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.063520 (rank : 248)
Query Neighborhood Hits	163	Target Neighborhood Hits	229	Shared Neighborhood Hits	22
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.065286 (rank : 243)
Query Neighborhood Hits	163	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.062140 (rank : 253)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.058572 (rank : 265)
Query Neighborhood Hits	163	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.063151 (rank : 250)
Query Neighborhood Hits	163	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CHFR_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.114315 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.114366 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	70
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

DTX3_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.068751 (rank : 229)
Query Neighborhood Hits	163	Target Neighborhood Hits	198	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.068186 (rank : 234)
Query Neighborhood Hits	163	Target Neighborhood Hits	202	Shared Neighborhood Hits	53
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

ERMAP_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.074956 (rank : 215)
Query Neighborhood Hits	163	Target Neighborhood Hits	155	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.067623 (rank : 237)
Query Neighborhood Hits	163	Target Neighborhood Hits	231	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

HNRPK_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.168708 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.168708 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

LNX1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.053925 (rank : 276)
Query Neighborhood Hits	163	Target Neighborhood Hits	379	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.056042 (rank : 273)
Query Neighborhood Hits	163	Target Neighborhood Hits	377	Shared Neighborhood Hits	64
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.052531 (rank : 277)
Query Neighborhood Hits	163	Target Neighborhood Hits	389	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.050833 (rank : 281)
Query Neighborhood Hits	163	Target Neighborhood Hits	407	Shared Neighborhood Hits	62
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MDM2_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.081867 (rank : 201)
Query Neighborhood Hits	163	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MDM2_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.067765 (rank : 236)
Query Neighborhood Hits	163	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

MDM4_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.084529 (rank : 199)
Query Neighborhood Hits	163	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MEFV_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.076702 (rank : 211)
Query Neighborhood Hits	163	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.073236 (rank : 219)
Query Neighborhood Hits	163	Target Neighborhood Hits	236	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.055181 (rank : 274)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCBP2_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.212942 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.212121 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

PML_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.072732 (rank : 220)
Query Neighborhood Hits	163	Target Neighborhood Hits	248	Shared Neighborhood Hits	50
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.068421 (rank : 233)
Query Neighborhood Hits	163	Target Neighborhood Hits	246	Shared Neighborhood Hits	49
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PZRN3_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.057464 (rank : 271)
Query Neighborhood Hits	163	Target Neighborhood Hits	461	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.057558 (rank : 270)
Query Neighborhood Hits	163	Target Neighborhood Hits	447	Shared Neighborhood Hits	67
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.058156 (rank : 267)
Query Neighborhood Hits	163	Target Neighborhood Hits	438	Shared Neighborhood Hits	67
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

R113A_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.064822 (rank : 244)
Query Neighborhood Hits	163	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.063606 (rank : 247)
Query Neighborhood Hits	163	Target Neighborhood Hits	165	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAD18_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.069853 (rank : 225)
Query Neighborhood Hits	163	Target Neighborhood Hits	284	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.072406 (rank : 221)
Query Neighborhood Hits	163	Target Neighborhood Hits	230	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAG1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.093147 (rank : 189)
Query Neighborhood Hits	163	Target Neighborhood Hits	203	Shared Neighborhood Hits	53
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.096059 (rank : 184)
Query Neighborhood Hits	163	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RFPL1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.074303 (rank : 218)
Query Neighborhood Hits	163	Target Neighborhood Hits	119	Shared Neighborhood Hits	24
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.078491 (rank : 207)
Query Neighborhood Hits	163	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.075939 (rank : 213)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	28
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFWD2_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.066802 (rank : 238)
Query Neighborhood Hits	163	Target Neighborhood Hits	518	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.069459 (rank : 227)
Query Neighborhood Hits	163	Target Neighborhood Hits	535	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.107835 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.106342 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	220	Shared Neighborhood Hits	66
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.096668 (rank : 178)
Query Neighborhood Hits	163	Target Neighborhood Hits	201	Shared Neighborhood Hits	63
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.096660 (rank : 179)
Query Neighborhood Hits	163	Target Neighborhood Hits	199	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN123_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.068443 (rank : 231)
Query Neighborhood Hits	163	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.069895 (rank : 224)
Query Neighborhood Hits	163	Target Neighborhood Hits	174	Shared Neighborhood Hits	56
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN141_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.110906 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	199	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.110450 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	200	Shared Neighborhood Hits	52
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.104010 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	162	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.103094 (rank : 166)
Query Neighborhood Hits	163	Target Neighborhood Hits	161	Shared Neighborhood Hits	55
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN165_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.055142 (rank : 275)
Query Neighborhood Hits	163	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN167_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.052150 (rank : 278)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	35
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN183_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.068425 (rank : 232)
Query Neighborhood Hits	163	Target Neighborhood Hits	126	Shared Neighborhood Hits	37
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.057805 (rank : 269)
Query Neighborhood Hits	163	Target Neighborhood Hits	119	Shared Neighborhood Hits	35
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.175273 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	213	Shared Neighborhood Hits	75
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.171339 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	211	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF13_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.058947 (rank : 262)
Query Neighborhood Hits	163	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.058785 (rank : 263)
Query Neighborhood Hits	163	Target Neighborhood Hits	164	Shared Neighborhood Hits	44
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF39_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.090475 (rank : 191)
Query Neighborhood Hits	163	Target Neighborhood Hits	200	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF41_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.078011 (rank : 208)
Query Neighborhood Hits	163	Target Neighborhood Hits	226	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.077631 (rank : 209)
Query Neighborhood Hits	163	Target Neighborhood Hits	224	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.107941 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	212	Shared Neighborhood Hits	55
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.104282 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	212	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.155233 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	206	Shared Neighborhood Hits	77
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.154905 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

SIA1A_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.059344 (rank : 261)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

SIA1B_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.060347 (rank : 256)
Query Neighborhood Hits	163	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

SIAH1_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.059384 (rank : 259)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

SIAH2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.074318 (rank : 217)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.074576 (rank : 216)
Query Neighborhood Hits	163	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SMRA3_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.100128 (rank : 171)
Query Neighborhood Hits	163	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SPRY4_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.065753 (rank : 241)
Query Neighborhood Hits	163	Target Neighborhood Hits	79	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.069318 (rank : 228)
Query Neighborhood Hits	163	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRAF2_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.050091 (rank : 283)
Query Neighborhood Hits	163	Target Neighborhood Hits	402	Shared Neighborhood Hits	40
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF4_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.051303 (rank : 279)
Query Neighborhood Hits	163	Target Neighborhood Hits	373	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF5_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.058009 (rank : 268)
Query Neighborhood Hits	163	Target Neighborhood Hits	355	Shared Neighborhood Hits	39
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI10_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.111259 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	315	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI10_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.109228 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	285	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI12_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.128812 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	387	Shared Neighborhood Hits	71
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI13_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.106072 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	274	Shared Neighborhood Hits	64
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.109420 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	282	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI14_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.071514 (rank : 222)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	25
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.071135 (rank : 223)
Query Neighborhood Hits	163	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI15_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.112944 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	395	Shared Neighborhood Hits	67
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI16_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.076514 (rank : 212)
Query Neighborhood Hits	163	Target Neighborhood Hits	231	Shared Neighborhood Hits	24
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.080502 (rank : 204)
Query Neighborhood Hits	163	Target Neighborhood Hits	196	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI17_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.120091 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	318	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI17_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.115191 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	620	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI22_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.113627 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	396	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI25_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.132918 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	472	Shared Neighborhood Hits	72
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI26_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.164931 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	339	Shared Neighborhood Hits	90
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI29_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.059660 (rank : 257)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	25
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.058628 (rank : 264)
Query Neighborhood Hits	163	Target Neighborhood Hits	306	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI30_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.114351 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	434	Shared Neighborhood Hits	67
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI31_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.143777 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	299	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.098363 (rank : 174)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.097301 (rank : 175)
Query Neighborhood Hits	163	Target Neighborhood Hits	271	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI34_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.104968 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	416	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.100545 (rank : 170)
Query Neighborhood Hits	163	Target Neighborhood Hits	332	Shared Neighborhood Hits	60
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI36_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.081348 (rank : 202)
Query Neighborhood Hits	163	Target Neighborhood Hits	282	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.081139 (rank : 203)
Query Neighborhood Hits	163	Target Neighborhood Hits	266	Shared Neighborhood Hits	45
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI38_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.106104 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	373	Shared Neighborhood Hits	67
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI40_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.142192 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	279	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI41_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.105267 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	349	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI42_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.063754 (rank : 246)
Query Neighborhood Hits	163	Target Neighborhood Hits	283	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.068153 (rank : 235)
Query Neighborhood Hits	163	Target Neighborhood Hits	316	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.058399 (rank : 266)
Query Neighborhood Hits	163	Target Neighborhood Hits	393	Shared Neighborhood Hits	24
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.061036 (rank : 255)
Query Neighborhood Hits	163	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI48_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.104932 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	192	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI49_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.096336 (rank : 182)
Query Neighborhood Hits	163	Target Neighborhood Hits	199	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI50_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.125920 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	294	Shared Neighborhood Hits	84
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.133746 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	326	Shared Neighborhood Hits	87
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI52_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.130205 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	213	Shared Neighborhood Hits	62
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI54_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.096379 (rank : 181)
Query Neighborhood Hits	163	Target Neighborhood Hits	209	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.096840 (rank : 177)
Query Neighborhood Hits	163	Target Neighborhood Hits	197	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.097047 (rank : 176)
Query Neighborhood Hits	163	Target Neighborhood Hits	292	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI59_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.103639 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.105276 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	292	Shared Neighborhood Hits	61
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI60_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.128086 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	85
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI60_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.109221 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI62_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.098982 (rank : 173)
Query Neighborhood Hits	163	Target Neighborhood Hits	584	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.101324 (rank : 168)
Query Neighborhood Hits	163	Target Neighborhood Hits	478	Shared Neighborhood Hits	61
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI63_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.094206 (rank : 187)
Query Neighborhood Hits	163	Target Neighborhood Hits	298	Shared Neighborhood Hits	50
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.095999 (rank : 185)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	49
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI65_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.149477 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	330	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI68_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.110096 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	267	Shared Neighborhood Hits	69
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI68_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.117936 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	356	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI73_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.125612 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	258	Shared Neighborhood Hits	78
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.120207 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	249	Shared Neighborhood Hits	77
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM2_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.104372 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	330	Shared Neighborhood Hits	72
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.103706 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	331	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.101579 (rank : 167)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	69
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.099396 (rank : 172)
Query Neighborhood Hits	163	Target Neighborhood Hits	351	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM4_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.126548 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	321	Shared Neighborhood Hits	78
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM5_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.121742 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	424	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM6_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.106593 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM6_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.110144 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	451	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM7_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.106853 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	336	Shared Neighborhood Hits	56
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM7_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.105537 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	358	Shared Neighborhood Hits	56
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM8_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.111424 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	650	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.111775 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	674	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM9_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.088179 (rank : 192)
Query Neighborhood Hits	163	Target Neighborhood Hits	294	Shared Neighborhood Hits	50
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.085860 (rank : 196)
Query Neighborhood Hits	163	Target Neighborhood Hits	274	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

ZN179_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.122779 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	178	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

Hits sorted by NC score

RKHD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RNF34_MOUSE
NC score	0.418432 (rank : 2)	θ value	0.00035302 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	160	Shared Neighborhood Hits	63
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.418223 (rank : 3)	θ value	0.00035302 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	63
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RFFL_MOUSE
NC score	0.417222 (rank : 4)	θ value	0.00035302 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
NC score	0.411443 (rank : 5)	θ value	0.00035302 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

BIRC7_HUMAN
NC score	0.382198 (rank : 6)	θ value	0.00390308 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	185	Shared Neighborhood Hits	73
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

FUBP1_HUMAN
NC score	0.370467 (rank : 7)	θ value	6.43352e-06 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	136	Shared Neighborhood Hits	30
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
NC score	0.370014 (rank : 8)	θ value	6.43352e-06 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	144	Shared Neighborhood Hits	31
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP3_HUMAN
NC score	0.368053 (rank : 9)	θ value	7.1131e-05 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	68	Shared Neighborhood Hits	28
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

NEUL1_HUMAN
NC score	0.365867 (rank : 10)	θ value	0.000121331 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
NC score	0.361027 (rank : 11)	θ value	0.00102713 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

BIRC3_HUMAN
NC score	0.354676 (rank : 12)	θ value	0.00035302 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
NC score	0.351850 (rank : 13)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC2_HUMAN
NC score	0.348222 (rank : 14)	θ value	0.00175202 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	142	Shared Neighborhood Hits	65
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
NC score	0.346872 (rank : 15)	θ value	0.00175202 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

FUBP2_HUMAN
NC score	0.346341 (rank : 16)	θ value	0.00869519 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

RNF26_HUMAN
NC score	0.342468 (rank : 17)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	95	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

BIRC8_HUMAN
NC score	0.331233 (rank : 18)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CGRF1_HUMAN
NC score	0.323861 (rank : 19)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
NC score	0.319017 (rank : 20)	θ value	0.0193708 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

BIRC4_HUMAN
NC score	0.303027 (rank : 21)	θ value	0.0431538 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
NC score	0.300362 (rank : 22)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	89	Shared Neighborhood Hits	49
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

MGRN1_HUMAN
NC score	0.285337 (rank : 23)	θ value	0.0431538 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

NOVA2_HUMAN
NC score	0.284761 (rank : 24)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

MGRN1_MOUSE
NC score	0.282108 (rank : 25)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

PEX10_HUMAN
NC score	0.273212 (rank : 26)	θ value	0.00869519 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	81
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TDRKH_MOUSE
NC score	0.272248 (rank : 27)	θ value	0.00228821 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_HUMAN
NC score	0.268347 (rank : 28)	θ value	0.00665767 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

VIGLN_MOUSE
NC score	0.268073 (rank : 29)	θ value	0.000786445 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

IF2B2_HUMAN
NC score	0.264400 (rank : 30)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

VIGLN_HUMAN
NC score	0.258870 (rank : 31)	θ value	0.0113563 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	71	Shared Neighborhood Hits	22
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

IF2B2_MOUSE
NC score	0.258691 (rank : 32)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	148	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

RN169_HUMAN
NC score	0.252818 (rank : 33)	θ value	0.00298849 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	203	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

NOVA1_HUMAN
NC score	0.252312 (rank : 34)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

MYLIP_HUMAN
NC score	0.243832 (rank : 35)	θ value	0.000158464 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PCBP3_MOUSE
NC score	0.243780 (rank : 36)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_HUMAN
NC score	0.243664 (rank : 37)	θ value	0.0113563 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP4_HUMAN
NC score	0.238595 (rank : 38)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

ZN313_MOUSE
NC score	0.236034 (rank : 39)	θ value	0.00509761 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

PCBP1_HUMAN
NC score	0.235521 (rank : 40)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
NC score	0.235521 (rank : 41)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

PCBP4_MOUSE
NC score	0.235121 (rank : 42)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

ZN313_HUMAN
NC score	0.222198 (rank : 43)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RN125_HUMAN
NC score	0.220428 (rank : 44)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	230	Shared Neighborhood Hits	70
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

MYLIP_MOUSE
NC score	0.218769 (rank : 45)	θ value	0.000461057 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	139	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PCBP2_HUMAN
NC score	0.212942 (rank : 46)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	163	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
NC score	0.212121 (rank : 47)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	163	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

CBLC_MOUSE
NC score	0.212110 (rank : 48)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	186	Shared Neighborhood Hits	71
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBLC_HUMAN
NC score	0.208708 (rank : 49)	θ value	0.813845 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	173	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBL_HUMAN
NC score	0.207311 (rank : 50)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	353	Shared Neighborhood Hits	79
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBLB_MOUSE
NC score	0.205662 (rank : 51)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	277	Shared Neighborhood Hits	79
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.204785 (rank : 52)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	261	Shared Neighborhood Hits	77
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBL_MOUSE
NC score	0.204028 (rank : 53)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	426	Shared Neighborhood Hits	83
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

RN168_HUMAN
NC score	0.199154 (rank : 54)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	370	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN166_HUMAN
NC score	0.198356 (rank : 55)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	65
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.197310 (rank : 56)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	248	Shared Neighborhood Hits	67
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN125_MOUSE
NC score	0.192996 (rank : 57)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	220	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN168_MOUSE
NC score	0.184131 (rank : 58)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	440	Shared Neighborhood Hits	80
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF8_MOUSE
NC score	0.182560 (rank : 59)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	618	Shared Neighborhood Hits	84
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF8_HUMAN
NC score	0.180636 (rank : 60)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	622	Shared Neighborhood Hits	84
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

LRSM1_MOUSE
NC score	0.176228 (rank : 61)	θ value	0.00869519 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	874	Shared Neighborhood Hits	64
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

RN185_HUMAN
NC score	0.175273 (rank : 62)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	163	Target Neighborhood Hits	213	Shared Neighborhood Hits	75
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI26_HUMAN
NC score	0.174496 (rank : 63)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	335	Shared Neighborhood Hits	89
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

RN185_MOUSE
NC score	0.171339 (rank : 64)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	163	Target Neighborhood Hits	211	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

HNRPK_HUMAN
NC score	0.168708 (rank : 65)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	163	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
NC score	0.168708 (rank : 66)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	163	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

TRI65_MOUSE
NC score	0.165399 (rank : 67)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	340	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI26_MOUSE
NC score	0.164931 (rank : 68)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	163	Target Neighborhood Hits	339	Shared Neighborhood Hits	90
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

BFAR_MOUSE
NC score	0.160722 (rank : 69)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	232	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

LRSM1_HUMAN
NC score	0.158986 (rank : 70)	θ value	0.00869519 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	1078	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

TRI35_HUMAN
NC score	0.155408 (rank : 71)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

RNF5_HUMAN
NC score	0.155233 (rank : 72)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	163	Target Neighborhood Hits	206	Shared Neighborhood Hits	77
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.154905 (rank : 73)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	163	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

BFAR_HUMAN
NC score	0.153172 (rank : 74)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	222	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RO52_HUMAN
NC score	0.150692 (rank : 75)	θ value	1.06291 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	419	Shared Neighborhood Hits	89
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI56_HUMAN
NC score	0.149525 (rank : 76)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	339	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI65_HUMAN
NC score	0.149477 (rank : 77)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	163	Target Neighborhood Hits	330	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI35_MOUSE
NC score	0.148160 (rank : 78)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	465	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

RO52_MOUSE
NC score	0.146242 (rank : 79)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	360	Shared Neighborhood Hits	87
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI25_MOUSE
NC score	0.144305 (rank : 80)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	446	Shared Neighborhood Hits	78
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI31_HUMAN
NC score	0.143777 (rank : 81)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	163	Target Neighborhood Hits	299	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI40_HUMAN
NC score	0.142192 (rank : 82)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	163	Target Neighborhood Hits	279	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI47_MOUSE
NC score	0.141757 (rank : 83)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	295	Shared Neighborhood Hits	75
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI43_HUMAN
NC score	0.141041 (rank : 84)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	341	Shared Neighborhood Hits	81
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI47_HUMAN
NC score	0.139998 (rank : 85)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	286	Shared Neighborhood Hits	72
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI27_MOUSE
NC score	0.137662 (rank : 86)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	261	Shared Neighborhood Hits	81
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI11_MOUSE
NC score	0.137207 (rank : 87)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	329	Shared Neighborhood Hits	78
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI56_MOUSE
NC score	0.136207 (rank : 88)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	72
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI11_HUMAN
NC score	0.135283 (rank : 89)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	316	Shared Neighborhood Hits	77
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI50_MOUSE
NC score	0.133746 (rank : 90)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	163	Target Neighborhood Hits	326	Shared Neighborhood Hits	87
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI25_HUMAN
NC score	0.132918 (rank : 91)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	163	Target Neighborhood Hits	472	Shared Neighborhood Hits	72
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI18_MOUSE
NC score	0.131730 (rank : 92)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI27_HUMAN
NC score	0.131292 (rank : 93)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	80
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI37_HUMAN
NC score	0.131262 (rank : 94)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	56
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.131175 (rank : 95)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	316	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI39_HUMAN
NC score	0.130807 (rank : 96)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	693	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI52_HUMAN
NC score	0.130205 (rank : 97)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	163	Target Neighborhood Hits	213	Shared Neighborhood Hits	62
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI39_MOUSE
NC score	0.129545 (rank : 98)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	691	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI12_MOUSE
NC score	0.128812 (rank : 99)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	163	Target Neighborhood Hits	387	Shared Neighborhood Hits	71
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

UHRF2_MOUSE
NC score	0.128729 (rank : 100)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	275	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

TRI60_HUMAN
NC score	0.128086 (rank : 101)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	85
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

UHRF2_HUMAN
NC score	0.127282 (rank : 102)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	269	Shared Neighborhood Hits	58
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

MIB1_MOUSE
NC score	0.126860 (rank : 103)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	471	Shared Neighborhood Hits	59
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

TRIM4_HUMAN
NC score	0.126548 (rank : 104)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	163	Target Neighborhood Hits	321	Shared Neighborhood Hits	78
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI50_HUMAN
NC score	0.125920 (rank : 105)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	163	Target Neighborhood Hits	294	Shared Neighborhood Hits	84
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

MIB1_HUMAN
NC score	0.125821 (rank : 106)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	470	Shared Neighborhood Hits	60
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

TRI73_HUMAN
NC score	0.125612 (rank : 107)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	163	Target Neighborhood Hits	258	Shared Neighborhood Hits	78
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI18_HUMAN
NC score	0.125345 (rank : 108)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	67
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRIM1_HUMAN
NC score	0.123784 (rank : 109)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	345	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.123132 (rank : 110)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	361	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

ZN179_HUMAN
NC score	0.122779 (rank : 111)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	163	Target Neighborhood Hits	178	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TOPRS_MOUSE
NC score	0.122682 (rank : 112)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	263	Shared Neighborhood Hits	52
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRIM5_HUMAN
NC score	0.121742 (rank : 113)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	163	Target Neighborhood Hits	424	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

RN103_HUMAN
NC score	0.121247 (rank : 114)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	43
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

TRI74_HUMAN
NC score	0.120207 (rank : 115)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	163	Target Neighborhood Hits	249	Shared Neighborhood Hits	77
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI17_HUMAN
NC score	0.120091 (rank : 116)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	163	Target Neighborhood Hits	318	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

AMFR_MOUSE
NC score	0.119576 (rank : 117)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	208	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TRI68_MOUSE
NC score	0.117936 (rank : 118)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	163	Target Neighborhood Hits	356	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

RN103_MOUSE
NC score	0.117750 (rank : 119)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

MIB2_HUMAN
NC score	0.117239 (rank : 120)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	438	Shared Neighborhood Hits	53
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

AMFR2_HUMAN
NC score	0.117202 (rank : 121)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

TRI17_MOUSE
NC score	0.115191 (rank : 122)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	163	Target Neighborhood Hits	620	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

CHFR_MOUSE
NC score	0.114366 (rank : 123)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	70
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI30_MOUSE
NC score	0.114351 (rank : 124)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	163	Target Neighborhood Hits	434	Shared Neighborhood Hits	67
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

CHFR_HUMAN
NC score	0.114315 (rank : 125)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI22_HUMAN
NC score	0.113627 (rank : 126)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	163	Target Neighborhood Hits	396	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TOPRS_HUMAN
NC score	0.113370 (rank : 127)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	286	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CM007_MOUSE
NC score	0.113354 (rank : 128)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	416	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

MIB2_MOUSE
NC score	0.113302 (rank : 129)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	409	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

TRI15_HUMAN
NC score	0.112944 (rank : 130)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	163	Target Neighborhood Hits	395	Shared Neighborhood Hits	67
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRIM8_MOUSE
NC score	0.111775 (rank : 131)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	163	Target Neighborhood Hits	674	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI46_HUMAN
NC score	0.111521 (rank : 132)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	291	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM8_HUMAN
NC score	0.111424 (rank : 133)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	163	Target Neighborhood Hits	650	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI10_HUMAN
NC score	0.111259 (rank : 134)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	163	Target Neighborhood Hits	315	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

RN141_HUMAN
NC score	0.110906 (rank : 135)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	163	Target Neighborhood Hits	199	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TRI46_MOUSE
NC score	0.110785 (rank : 136)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	287	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

SMRA3_HUMAN
NC score	0.110680 (rank : 137)	θ value	0.365318 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	265	Shared Neighborhood Hits	74
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

RN141_MOUSE
NC score	0.110450 (rank : 138)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	163	Target Neighborhood Hits	200	Shared Neighborhood Hits	52
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TRIM6_MOUSE
NC score	0.110144 (rank : 139)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	163	Target Neighborhood Hits	451	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI68_HUMAN
NC score	0.110096 (rank : 140)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	163	Target Neighborhood Hits	267	Shared Neighborhood Hits	69
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI13_MOUSE
NC score	0.109420 (rank : 141)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	163	Target Neighborhood Hits	282	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI10_MOUSE
NC score	0.109228 (rank : 142)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	163	Target Neighborhood Hits	285	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI60_MOUSE
NC score	0.109221 (rank : 143)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

RNF4_HUMAN
NC score	0.107941 (rank : 144)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	163	Target Neighborhood Hits	212	Shared Neighborhood Hits	55
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RING1_HUMAN
NC score	0.107835 (rank : 145)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

BRCA1_MOUSE
NC score	0.107826 (rank : 146)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	163	Target Neighborhood Hits	436	Shared Neighborhood Hits	70
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TRIM7_HUMAN
NC score	0.106853 (rank : 147)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	163	Target Neighborhood Hits	336	Shared Neighborhood Hits	56
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM6_HUMAN
NC score	0.106593 (rank : 148)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	163	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

RING1_MOUSE
NC score	0.106342 (rank : 149)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	163	Target Neighborhood Hits	220	Shared Neighborhood Hits	66
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI38_HUMAN
NC score	0.106104 (rank : 150)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	163	Target Neighborhood Hits	373	Shared Neighborhood Hits	67
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

UHRF1_MOUSE
NC score	0.106094 (rank : 151)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	278	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

TRI13_HUMAN
NC score	0.106072 (rank : 152)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	163	Target Neighborhood Hits	274	Shared Neighborhood Hits	64
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRIM7_MOUSE
NC score	0.105537 (rank : 153)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	163	Target Neighborhood Hits	358	Shared Neighborhood Hits	56
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI59_MOUSE
NC score	0.105276 (rank : 154)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	163	Target Neighborhood Hits	292	Shared Neighborhood Hits	61
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI41_HUMAN
NC score	0.105267 (rank : 155)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	163	Target Neighborhood Hits	349	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI34_HUMAN
NC score	0.104968 (rank : 156)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	163	Target Neighborhood Hits	416	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI48_HUMAN
NC score	0.104932 (rank : 157)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	163	Target Neighborhood Hits	192	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

CM007_HUMAN
NC score	0.104574 (rank : 158)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	422	Shared Neighborhood Hits	42
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRIM2_HUMAN
NC score	0.104372 (rank : 159)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	163	Target Neighborhood Hits	330	Shared Neighborhood Hits	72
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

RNF4_MOUSE
NC score	0.104282 (rank : 160)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	163	Target Neighborhood Hits	212	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RN146_HUMAN
NC score	0.104010 (rank : 161)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	163	Target Neighborhood Hits	162	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

BRCA1_HUMAN
NC score	0.103870 (rank : 162)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	163	Target Neighborhood Hits	381	Shared Neighborhood Hits	68
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRIM2_MOUSE
NC score	0.103706 (rank : 163)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	163	Target Neighborhood Hits	331	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI59_HUMAN
NC score	0.103639 (rank : 164)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

BIRC5_MOUSE
NC score	0.103208 (rank : 165)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	163	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

RN146_MOUSE
NC score	0.103094 (rank : 166)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	163	Target Neighborhood Hits	161	Shared Neighborhood Hits	55
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRIM3_HUMAN
NC score	0.101579 (rank : 167)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	69
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI62_MOUSE
NC score	0.101324 (rank : 168)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	163	Target Neighborhood Hits	478	Shared Neighborhood Hits	61
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

UHRF1_HUMAN
NC score	0.101115 (rank : 169)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	272	Shared Neighborhood Hits	58
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

TRI34_MOUSE
NC score	0.100545 (rank : 170)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	163	Target Neighborhood Hits	332	Shared Neighborhood Hits	60
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

SMRA3_MOUSE
NC score	0.100128 (rank : 171)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	163	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRIM3_MOUSE
NC score	0.099396 (rank : 172)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	163	Target Neighborhood Hits	351	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI62_HUMAN
NC score	0.098982 (rank : 173)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	163	Target Neighborhood Hits	584	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI32_HUMAN
NC score	0.098363 (rank : 174)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.097301 (rank : 175)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	163	Target Neighborhood Hits	271	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI55_HUMAN
NC score	0.097047 (rank : 176)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	163	Target Neighborhood Hits	292	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI54_MOUSE
NC score	0.096840 (rank : 177)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	163	Target Neighborhood Hits	197	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

RING2_HUMAN
NC score	0.096668 (rank : 178)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	163	Target Neighborhood Hits	201	Shared Neighborhood Hits	63
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.096660 (rank : 179)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	163	Target Neighborhood Hits	199	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

SAM68_HUMAN
NC score	0.096537 (rank : 180)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

TRI54_HUMAN
NC score	0.096379 (rank : 181)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	163	Target Neighborhood Hits	209	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI49_HUMAN
NC score	0.096336 (rank : 182)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	163	Target Neighborhood Hits	199	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

SAM68_MOUSE
NC score	0.096207 (rank : 183)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

RAG1_MOUSE
NC score	0.096059 (rank : 184)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	163	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI63_MOUSE
NC score	0.095999 (rank : 185)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	49
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

BIRC5_HUMAN
NC score	0.095937 (rank : 186)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	163	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

TRI63_HUMAN
NC score	0.094206 (rank : 187)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	163	Target Neighborhood Hits	298	Shared Neighborhood Hits	50
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRAF6_MOUSE
NC score	0.093275 (rank : 188)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	60
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

RAG1_HUMAN
NC score	0.093147 (rank : 189)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	163	Target Neighborhood Hits	203	Shared Neighborhood Hits	53
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

TRAF6_HUMAN
NC score	0.091982 (rank : 190)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	267	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

RNF39_HUMAN
NC score	0.090475 (rank : 191)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	163	Target Neighborhood Hits	200	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRIM9_HUMAN
NC score	0.088179 (rank : 192)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	163	Target Neighborhood Hits	294	Shared Neighborhood Hits	50
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

BIRC1_HUMAN
NC score	0.086911 (rank : 193)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	163	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1E_MOUSE
NC score	0.086215 (rank : 194)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	163	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
NC score	0.085972 (rank : 195)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	163	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

TRIM9_MOUSE
NC score	0.085860 (rank : 196)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	163	Target Neighborhood Hits	274	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

BIR1G_MOUSE
NC score	0.085837 (rank : 197)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	163	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1B_MOUSE
NC score	0.085471 (rank : 198)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	163	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

MDM4_HUMAN
NC score	0.084529 (rank : 199)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	163	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

BIR1A_MOUSE
NC score	0.084046 (rank : 200)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

MDM2_HUMAN
NC score	0.081867 (rank : 201)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	163	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

TRI36_HUMAN
NC score	0.081348 (rank : 202)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	163	Target Neighborhood Hits	282	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
NC score	0.081139 (rank : 203)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	163	Target Neighborhood Hits	266	Shared Neighborhood Hits	45
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI16_MOUSE
NC score	0.080502 (rank : 204)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	163	Target Neighborhood Hits	196	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BSPRY_MOUSE
NC score	0.078852 (rank : 205)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_HUMAN
NC score	0.078509 (rank : 206)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	163	Target Neighborhood Hits	115	Shared Neighborhood Hits	24
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RFPL2_HUMAN
NC score	0.078491 (rank : 207)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	163	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RNF41_HUMAN
NC score	0.078011 (rank : 208)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	163	Target Neighborhood Hits	226	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.077631 (rank : 209)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	163	Target Neighborhood Hits	224	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SF01_MOUSE
NC score	0.076873 (rank : 210)	θ value	1.06291 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	16
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

MEFV_HUMAN
NC score	0.076702 (rank : 211)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	163	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI16_HUMAN
NC score	0.076514 (rank : 212)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	163	Target Neighborhood Hits	231	Shared Neighborhood Hits	24
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

RFPL3_HUMAN
NC score	0.075939 (rank : 213)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	28
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

SF01_HUMAN
NC score	0.075194 (rank : 214)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

ERMAP_HUMAN
NC score	0.074956 (rank : 215)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	163	Target Neighborhood Hits	155	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

SIAH2_MOUSE
NC score	0.074576 (rank : 216)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	163	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SIAH2_HUMAN
NC score	0.074318 (rank : 217)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

RFPL1_HUMAN
NC score	0.074303 (rank : 218)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	163	Target Neighborhood Hits	119	Shared Neighborhood Hits	24
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

MEFV_MOUSE
NC score	0.073236 (rank : 219)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	163	Target Neighborhood Hits	236	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

PML_HUMAN
NC score	0.072732 (rank : 220)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	163	Target Neighborhood Hits	248	Shared Neighborhood Hits	50
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RAD18_MOUSE
NC score	0.072406 (rank : 221)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	163	Target Neighborhood Hits	230	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

TRI14_HUMAN
NC score	0.071514 (rank : 222)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	25
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
NC score	0.071135 (rank : 223)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	163	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

RN123_MOUSE
NC score	0.069895 (rank : 224)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	163	Target Neighborhood Hits	174	Shared Neighborhood Hits	56
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RAD18_HUMAN
NC score	0.069853 (rank : 225)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	163	Target Neighborhood Hits	284	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RBBP6_MOUSE
NC score	0.069682 (rank : 226)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	1014	Shared Neighborhood Hits	59
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RFWD2_MOUSE
NC score	0.069459 (rank : 227)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	163	Target Neighborhood Hits	535	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

SPRY4_MOUSE
NC score	0.069318 (rank : 228)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	163	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

DTX3_HUMAN
NC score	0.068751 (rank : 229)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	163	Target Neighborhood Hits	198	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

AKAP1_HUMAN
NC score	0.068484 (rank : 230)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

RN123_HUMAN
NC score	0.068443 (rank : 231)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	163	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN183_HUMAN
NC score	0.068425 (rank : 232)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	163	Target Neighborhood Hits	126	Shared Neighborhood Hits	37
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

PML_MOUSE
NC score	0.068421 (rank : 233)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	163	Target Neighborhood Hits	246	Shared Neighborhood Hits	49
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

DTX3_MOUSE
NC score	0.068186 (rank : 234)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	163	Target Neighborhood Hits	202	Shared Neighborhood Hits	53
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TRI42_MOUSE
NC score	0.068153 (rank : 235)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	163	Target Neighborhood Hits	316	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

MDM2_MOUSE
NC score	0.067765 (rank : 236)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	163	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

ERMAP_MOUSE
NC score	0.067623 (rank : 237)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	163	Target Neighborhood Hits	231	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

RFWD2_HUMAN
NC score	0.066802 (rank : 238)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	163	Target Neighborhood Hits	518	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

AKAP1_MOUSE
NC score	0.066783 (rank : 239)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

BT1A1_MOUSE
NC score	0.065783 (rank : 240)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	163	Target Neighborhood Hits	252	Shared Neighborhood Hits	22
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

SPRY4_HUMAN
NC score	0.065753 (rank : 241)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	163	Target Neighborhood Hits	79	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BT1A1_HUMAN
NC score	0.065414 (rank : 242)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	163	Target Neighborhood Hits	322	Shared Neighborhood Hits	22
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A3_HUMAN
NC score	0.065286 (rank : 243)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	163	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

R113A_HUMAN
NC score	0.064822 (rank : 244)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	163	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

BT2A2_HUMAN
NC score	0.064670 (rank : 245)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	163	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRI42_HUMAN
NC score	0.063754 (rank : 246)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	163	Target Neighborhood Hits	283	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

R113B_HUMAN
NC score	0.063606 (rank : 247)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	163	Target Neighborhood Hits	165	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

BT3A1_HUMAN
NC score	0.063520 (rank : 248)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	163	Target Neighborhood Hits	229	Shared Neighborhood Hits	22
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BIRC6_HUMAN
NC score	0.063328 (rank : 249)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	163	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

BTNL9_HUMAN
NC score	0.063151 (rank : 250)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	163	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

RBBP6_HUMAN
NC score	0.062815 (rank : 251)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	1135	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

BT2A3_HUMAN
NC score	0.062539 (rank : 252)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	163	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BTNL3_HUMAN
NC score	0.062140 (rank : 253)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BT2A1_HUMAN
NC score	0.061055 (rank : 254)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	163	Target Neighborhood Hits	185	Shared Neighborhood Hits	20
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

TRI44_MOUSE
NC score	0.061036 (rank : 255)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	163	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

SIA1B_MOUSE
NC score	0.060347 (rank : 256)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	163	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

TRI29_HUMAN
NC score	0.059660 (rank : 257)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	25
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRAF3_MOUSE
NC score	0.059640 (rank : 258)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	476	Shared Neighborhood Hits	48
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

SIAH1_HUMAN
NC score	0.059384 (rank : 259)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

IASPP_MOUSE
NC score	0.059370 (rank : 260)	θ value	0.00509761 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	1024	Shared Neighborhood Hits	20
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SIA1A_MOUSE
NC score	0.059344 (rank : 261)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

RNF13_HUMAN
NC score	0.058947 (rank : 262)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	163	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
NC score	0.058785 (rank : 263)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	163	Target Neighborhood Hits	164	Shared Neighborhood Hits	44
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

TRI29_MOUSE
NC score	0.058628 (rank : 264)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	163	Target Neighborhood Hits	306	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

BTNL8_HUMAN
NC score	0.058572 (rank : 265)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	163	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

TRI44_HUMAN
NC score	0.058399 (rank : 266)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	163	Target Neighborhood Hits	393	Shared Neighborhood Hits	24
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

PZRN4_HUMAN
NC score	0.058156 (rank : 267)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	163	Target Neighborhood Hits	438	Shared Neighborhood Hits	67
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRAF5_MOUSE
NC score	0.058009 (rank : 268)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	163	Target Neighborhood Hits	355	Shared Neighborhood Hits	39
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

RN183_MOUSE
NC score	0.057805 (rank : 269)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	163	Target Neighborhood Hits	119	Shared Neighborhood Hits	35
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

PZRN3_MOUSE
NC score	0.057558 (rank : 270)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	163	Target Neighborhood Hits	447	Shared Neighborhood Hits	67
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.057464 (rank : 271)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	163	Target Neighborhood Hits	461	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAF3_HUMAN
NC score	0.057101 (rank : 272)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	463	Shared Neighborhood Hits	44
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

LNX1_MOUSE
NC score	0.056042 (rank : 273)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	163	Target Neighborhood Hits	377	Shared Neighborhood Hits	64
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

NHLC1_MOUSE
NC score	0.055181 (rank : 274)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RN165_HUMAN
NC score	0.055142 (rank : 275)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	163	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

LNX1_HUMAN
NC score	0.053925 (rank : 276)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	163	Target Neighborhood Hits	379	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
NC score	0.052531 (rank : 277)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	163	Target Neighborhood Hits	389	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RN167_MOUSE
NC score	0.052150 (rank : 278)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	35
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

TRAF4_HUMAN
NC score	0.051303 (rank : 279)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	163	Target Neighborhood Hits	373	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

OGFR_HUMAN
NC score	0.051273 (rank : 280)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	1582	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

LNX2_MOUSE
NC score	0.050833 (rank : 281)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	163	Target Neighborhood Hits	407	Shared Neighborhood Hits	62
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

HRB2_HUMAN
NC score	0.050570 (rank : 282)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q13601, Q8NEA8, Q8TC37, Q96AT5	Gene names	HRB2
Domain Architecture	No domain graphic available
Description	HIV-1 Rev-binding protein 2 (Rev-interacting protein 1) (Rip-1).

TRAF2_HUMAN
NC score	0.050091 (rank : 283)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	163	Target Neighborhood Hits	402	Shared Neighborhood Hits	40
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

HRB2_MOUSE
NC score	0.049188 (rank : 284)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGA5, Q8C029	Gene names	Hrb2
Domain Architecture	No domain graphic available
Description	HIV-1 Rev-binding protein 2 homolog.

PNPT1_HUMAN
NC score	0.048896 (rank : 285)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

CA104_HUMAN
NC score	0.046606 (rank : 286)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q66K80, Q8NA07	Gene names	C1orf104
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf104.

FXR2_HUMAN
NC score	0.042977 (rank : 287)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

PO121_MOUSE
NC score	0.042770 (rank : 288)	θ value	1.06291 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	345	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

CO8A2_HUMAN
NC score	0.040882 (rank : 289)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	299	Shared Neighborhood Hits	12
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

NACAM_MOUSE
NC score	0.040785 (rank : 290)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	1866	Shared Neighborhood Hits	27
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TIP60_HUMAN
NC score	0.040267 (rank : 291)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
NC score	0.040237 (rank : 292)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

CO8A2_MOUSE
NC score	0.039638 (rank : 293)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

DDX53_HUMAN
NC score	0.038493 (rank : 294)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	124	Shared Neighborhood Hits	21
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DBPA_MOUSE
NC score	0.036509 (rank : 295)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKB3, Q80WG4, Q9EQF7, Q9EQF8	Gene names	Csda, Msy4, Ybx3
Domain Architecture	No domain graphic available
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Y-box protein 3).

ARD1_MOUSE
NC score	0.036183 (rank : 296)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	573	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

DCDC2_HUMAN
NC score	0.034448 (rank : 297)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

CO4A2_MOUSE
NC score	0.033167 (rank : 298)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	492	Shared Neighborhood Hits	18
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

ANKZ1_HUMAN
NC score	0.032857 (rank : 299)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

PEX2_HUMAN
NC score	0.031964 (rank : 300)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

MAML2_HUMAN
NC score	0.030825 (rank : 301)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

ASCC1_MOUSE
NC score	0.030231 (rank : 302)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D8Z1, Q3TAC2	Gene names	Ascc1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50).

DDX43_HUMAN
NC score	0.028265 (rank : 303)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

COCA1_HUMAN
NC score	0.026345 (rank : 304)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	458	Shared Neighborhood Hits	8
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

URFB1_HUMAN
NC score	0.025560 (rank : 305)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

MT4_HUMAN
NC score	0.024783 (rank : 306)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

COCA1_MOUSE
NC score	0.024602 (rank : 307)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	467	Shared Neighborhood Hits	9
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MUC5B_HUMAN
NC score	0.024102 (rank : 308)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	1020	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

EMID2_HUMAN
NC score	0.023328 (rank : 309)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

CSKI1_MOUSE
NC score	0.022953 (rank : 310)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	1031	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TAF3_HUMAN
NC score	0.021818 (rank : 311)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	568	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

FGD5_HUMAN
NC score	0.019376 (rank : 312)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

SENP3_MOUSE
NC score	0.018246 (rank : 313)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

ZDHC5_HUMAN
NC score	0.017301 (rank : 314)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

FGD5_MOUSE
NC score	0.016686 (rank : 315)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

SEPT9_HUMAN
NC score	0.011026 (rank : 316)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	706	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

NLGN2_HUMAN
NC score	0.010374 (rank : 317)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
NC score	0.010215 (rank : 318)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

BBX_MOUSE
NC score	0.010048 (rank : 319)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

ZAN_MOUSE
NC score	0.009689 (rank : 320)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	808	Shared Neighborhood Hits	8
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

TNR3_HUMAN
NC score	0.009641 (rank : 321)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

KCNQ4_HUMAN
NC score	0.008413 (rank : 322)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

OST4_HUMAN
NC score	0.006445 (rank : 323)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

HXA13_HUMAN
NC score	0.003499 (rank : 324)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	353	Shared Neighborhood Hits	4
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

AATK_HUMAN
NC score	0.002873 (rank : 325)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	1243	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CRX_MOUSE
NC score	0.002447 (rank : 326)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

M3K12_MOUSE
NC score	-0.001386 (rank : 327)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	957	Shared Neighborhood Hits	5
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_HUMAN
NC score	-0.001954 (rank : 328)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	940	Shared Neighborhood Hits	6
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).