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Network neighborhood for query Sequence : TRI46_MOUSE

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TRI46_MOUSE
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRI46_HUMAN
θ value	0 (rank : 1)	NC score	0.998211 (rank : 2)
Query Neighborhood Hits	287	Target Neighborhood Hits	291	Shared Neighborhood Hits	274
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	287	Target Neighborhood Hits	287	Shared Neighborhood Hits	287
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI36_MOUSE
θ value	9.76035e-180 (rank : 3)	NC score	0.953432 (rank : 3)
Query Neighborhood Hits	287	Target Neighborhood Hits	266	Shared Neighborhood Hits	175
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI36_HUMAN
θ value	2.93876e-176 (rank : 4)	NC score	0.951992 (rank : 4)
Query Neighborhood Hits	287	Target Neighborhood Hits	282	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI18_MOUSE
θ value	4.54686e-52 (rank : 5)	NC score	0.852339 (rank : 7)
Query Neighborhood Hits	287	Target Neighborhood Hits	292	Shared Neighborhood Hits	191
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRIM1_MOUSE
θ value	2.25659e-51 (rank : 6)	NC score	0.855246 (rank : 5)
Query Neighborhood Hits	287	Target Neighborhood Hits	361	Shared Neighborhood Hits	205
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI18_HUMAN
θ value	1.61718e-49 (rank : 7)	NC score	0.847000 (rank : 8)
Query Neighborhood Hits	287	Target Neighborhood Hits	307	Shared Neighborhood Hits	193
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRIM1_HUMAN
θ value	1.36902e-48 (rank : 8)	NC score	0.853788 (rank : 6)
Query Neighborhood Hits	287	Target Neighborhood Hits	345	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM9_HUMAN
θ value	2.26182e-43 (rank : 9)	NC score	0.836074 (rank : 9)
Query Neighborhood Hits	287	Target Neighborhood Hits	294	Shared Neighborhood Hits	181
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	1.3722e-40 (rank : 10)	NC score	0.826826 (rank : 10)
Query Neighborhood Hits	287	Target Neighborhood Hits	274	Shared Neighborhood Hits	174
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI55_HUMAN
θ value	8.61488e-35 (rank : 11)	NC score	0.817346 (rank : 13)
Query Neighborhood Hits	287	Target Neighborhood Hits	292	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI63_MOUSE
θ value	2.50655e-34 (rank : 12)	NC score	0.823202 (rank : 11)
Query Neighborhood Hits	287	Target Neighborhood Hits	240	Shared Neighborhood Hits	170
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI54_HUMAN
θ value	5.584e-34 (rank : 13)	NC score	0.815603 (rank : 14)
Query Neighborhood Hits	287	Target Neighborhood Hits	209	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	1.24399e-33 (rank : 14)	NC score	0.819725 (rank : 12)
Query Neighborhood Hits	287	Target Neighborhood Hits	197	Shared Neighborhood Hits	154
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI63_HUMAN
θ value	2.27234e-27 (rank : 15)	NC score	0.805727 (rank : 15)
Query Neighborhood Hits	287	Target Neighborhood Hits	298	Shared Neighborhood Hits	171
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI42_MOUSE
θ value	2.27762e-19 (rank : 16)	NC score	0.689263 (rank : 17)
Query Neighborhood Hits	287	Target Neighborhood Hits	316	Shared Neighborhood Hits	136
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_HUMAN
θ value	5.60996e-18 (rank : 17)	NC score	0.686415 (rank : 18)
Query Neighborhood Hits	287	Target Neighborhood Hits	283	Shared Neighborhood Hits	135
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRIM8_MOUSE
θ value	1.16975e-15 (rank : 18)	NC score	0.689585 (rank : 16)
Query Neighborhood Hits	287	Target Neighborhood Hits	674	Shared Neighborhood Hits	201
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
θ value	2.43908e-13 (rank : 19)	NC score	0.685802 (rank : 19)
Query Neighborhood Hits	287	Target Neighborhood Hits	650	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI45_HUMAN
θ value	7.09661e-13 (rank : 20)	NC score	0.623894 (rank : 25)
Query Neighborhood Hits	287	Target Neighborhood Hits	155	Shared Neighborhood Hits	115
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	1.58096e-12 (rank : 21)	NC score	0.625119 (rank : 24)
Query Neighborhood Hits	287	Target Neighborhood Hits	155	Shared Neighborhood Hits	103
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI47_HUMAN
θ value	1.74796e-11 (rank : 22)	NC score	0.601502 (rank : 29)
Query Neighborhood Hits	287	Target Neighborhood Hits	286	Shared Neighborhood Hits	179
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI59_HUMAN
θ value	6.64225e-11 (rank : 23)	NC score	0.667460 (rank : 21)
Query Neighborhood Hits	287	Target Neighborhood Hits	307	Shared Neighborhood Hits	167
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI15_HUMAN
θ value	8.67504e-11 (rank : 24)	NC score	0.503091 (rank : 63)
Query Neighborhood Hits	287	Target Neighborhood Hits	395	Shared Neighborhood Hits	185
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI59_MOUSE
θ value	1.47974e-10 (rank : 25)	NC score	0.670305 (rank : 20)
Query Neighborhood Hits	287	Target Neighborhood Hits	292	Shared Neighborhood Hits	170
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI47_MOUSE
θ value	2.52405e-10 (rank : 26)	NC score	0.608411 (rank : 27)
Query Neighborhood Hits	287	Target Neighborhood Hits	295	Shared Neighborhood Hits	175
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TIF1G_MOUSE
θ value	2.13673e-09 (rank : 27)	NC score	0.477630 (rank : 90)
Query Neighborhood Hits	287	Target Neighborhood Hits	498	Shared Neighborhood Hits	118
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI29_MOUSE
θ value	6.21693e-09 (rank : 28)	NC score	0.553853 (rank : 39)
Query Neighborhood Hits	287	Target Neighborhood Hits	306	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TIF1G_HUMAN
θ value	8.11959e-09 (rank : 29)	NC score	0.481449 (rank : 87)
Query Neighborhood Hits	287	Target Neighborhood Hits	410	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRI11_HUMAN
θ value	1.06045e-08 (rank : 30)	NC score	0.498417 (rank : 66)
Query Neighborhood Hits	287	Target Neighborhood Hits	316	Shared Neighborhood Hits	179
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI39_HUMAN
θ value	1.38499e-08 (rank : 31)	NC score	0.509353 (rank : 54)
Query Neighborhood Hits	287	Target Neighborhood Hits	693	Shared Neighborhood Hits	207
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI11_MOUSE
θ value	2.36244e-08 (rank : 32)	NC score	0.491440 (rank : 73)
Query Neighborhood Hits	287	Target Neighborhood Hits	329	Shared Neighborhood Hits	181
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI29_HUMAN
θ value	2.36244e-08 (rank : 33)	NC score	0.547244 (rank : 42)
Query Neighborhood Hits	287	Target Neighborhood Hits	273	Shared Neighborhood Hits	107
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI56_MOUSE
θ value	2.36244e-08 (rank : 34)	NC score	0.615855 (rank : 26)
Query Neighborhood Hits	287	Target Neighborhood Hits	255	Shared Neighborhood Hits	157
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI39_MOUSE
θ value	4.0297e-08 (rank : 35)	NC score	0.505617 (rank : 57)
Query Neighborhood Hits	287	Target Neighborhood Hits	691	Shared Neighborhood Hits	207
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI41_HUMAN
θ value	5.26297e-08 (rank : 36)	NC score	0.519786 (rank : 49)
Query Neighborhood Hits	287	Target Neighborhood Hits	349	Shared Neighborhood Hits	184
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TIF1A_HUMAN
θ value	6.87365e-08 (rank : 37)	NC score	0.425610 (rank : 101)
Query Neighborhood Hits	287	Target Neighborhood Hits	327	Shared Neighborhood Hits	105
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	6.87365e-08 (rank : 38)	NC score	0.396044 (rank : 111)
Query Neighborhood Hits	287	Target Neighborhood Hits	307	Shared Neighborhood Hits	98
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

ARD1_HUMAN
θ value	8.97725e-08 (rank : 39)	NC score	0.281648 (rank : 148)
Query Neighborhood Hits	287	Target Neighborhood Hits	621	Shared Neighborhood Hits	90
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

TRI17_HUMAN
θ value	8.97725e-08 (rank : 40)	NC score	0.505210 (rank : 59)
Query Neighborhood Hits	287	Target Neighborhood Hits	318	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI62_MOUSE
θ value	8.97725e-08 (rank : 41)	NC score	0.533770 (rank : 45)
Query Neighborhood Hits	287	Target Neighborhood Hits	478	Shared Neighborhood Hits	191
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_HUMAN
θ value	1.99992e-07 (rank : 42)	NC score	0.532816 (rank : 47)
Query Neighborhood Hits	287	Target Neighborhood Hits	584	Shared Neighborhood Hits	199
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI17_MOUSE
θ value	2.61198e-07 (rank : 43)	NC score	0.509888 (rank : 53)
Query Neighborhood Hits	287	Target Neighborhood Hits	620	Shared Neighborhood Hits	202
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI50_HUMAN
θ value	3.41135e-07 (rank : 44)	NC score	0.550005 (rank : 41)
Query Neighborhood Hits	287	Target Neighborhood Hits	294	Shared Neighborhood Hits	185
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI38_HUMAN
θ value	7.59969e-07 (rank : 45)	NC score	0.488662 (rank : 77)
Query Neighborhood Hits	287	Target Neighborhood Hits	373	Shared Neighborhood Hits	186
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI66_HUMAN
θ value	9.92553e-07 (rank : 46)	NC score	0.291088 (rank : 143)
Query Neighborhood Hits	287	Target Neighborhood Hits	479	Shared Neighborhood Hits	75
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI50_MOUSE
θ value	1.29631e-06 (rank : 47)	NC score	0.550222 (rank : 40)
Query Neighborhood Hits	287	Target Neighborhood Hits	326	Shared Neighborhood Hits	193
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ARD1_MOUSE
θ value	1.69304e-06 (rank : 48)	NC score	0.287406 (rank : 145)
Query Neighborhood Hits	287	Target Neighborhood Hits	573	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

TRI25_HUMAN
θ value	1.69304e-06 (rank : 49)	NC score	0.602288 (rank : 28)
Query Neighborhood Hits	287	Target Neighborhood Hits	472	Shared Neighborhood Hits	198
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRIM7_MOUSE
θ value	2.21117e-06 (rank : 50)	NC score	0.505603 (rank : 58)
Query Neighborhood Hits	287	Target Neighborhood Hits	358	Shared Neighborhood Hits	181
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI56_HUMAN
θ value	2.88788e-06 (rank : 51)	NC score	0.592975 (rank : 32)
Query Neighborhood Hits	287	Target Neighborhood Hits	339	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRIM3_MOUSE
θ value	2.88788e-06 (rank : 52)	NC score	0.596519 (rank : 30)
Query Neighborhood Hits	287	Target Neighborhood Hits	351	Shared Neighborhood Hits	171
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TIF1B_HUMAN
θ value	3.77169e-06 (rank : 53)	NC score	0.487218 (rank : 80)
Query Neighborhood Hits	287	Target Neighborhood Hits	312	Shared Neighborhood Hits	109
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	3.77169e-06 (rank : 54)	NC score	0.480075 (rank : 88)
Query Neighborhood Hits	287	Target Neighborhood Hits	276	Shared Neighborhood Hits	106
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI66_MOUSE
θ value	3.77169e-06 (rank : 55)	NC score	0.296486 (rank : 138)
Query Neighborhood Hits	287	Target Neighborhood Hits	491	Shared Neighborhood Hits	81
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI27_HUMAN
θ value	4.92598e-06 (rank : 56)	NC score	0.496890 (rank : 68)
Query Neighborhood Hits	287	Target Neighborhood Hits	273	Shared Neighborhood Hits	176
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI44_HUMAN
θ value	4.92598e-06 (rank : 57)	NC score	0.498614 (rank : 65)
Query Neighborhood Hits	287	Target Neighborhood Hits	393	Shared Neighborhood Hits	106
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	6.43352e-06 (rank : 58)	NC score	0.505179 (rank : 60)
Query Neighborhood Hits	287	Target Neighborhood Hits	327	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI14_HUMAN
θ value	8.40245e-06 (rank : 59)	NC score	0.539307 (rank : 44)
Query Neighborhood Hits	287	Target Neighborhood Hits	143	Shared Neighborhood Hits	108
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI27_MOUSE
θ value	8.40245e-06 (rank : 60)	NC score	0.494150 (rank : 71)
Query Neighborhood Hits	287	Target Neighborhood Hits	261	Shared Neighborhood Hits	169
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

RO52_HUMAN
θ value	1.43324e-05 (rank : 61)	NC score	0.478209 (rank : 89)
Query Neighborhood Hits	287	Target Neighborhood Hits	419	Shared Neighborhood Hits	203
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI16_HUMAN
θ value	1.87187e-05 (rank : 62)	NC score	0.488290 (rank : 78)
Query Neighborhood Hits	287	Target Neighborhood Hits	231	Shared Neighborhood Hits	112
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI73_HUMAN
θ value	1.87187e-05 (rank : 63)	NC score	0.585320 (rank : 33)
Query Neighborhood Hits	287	Target Neighborhood Hits	258	Shared Neighborhood Hits	186
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	1.87187e-05 (rank : 64)	NC score	0.583488 (rank : 35)
Query Neighborhood Hits	287	Target Neighborhood Hits	249	Shared Neighborhood Hits	179
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI34_MOUSE
θ value	3.19293e-05 (rank : 65)	NC score	0.481865 (rank : 85)
Query Neighborhood Hits	287	Target Neighborhood Hits	332	Shared Neighborhood Hits	176
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI30_MOUSE
θ value	4.1701e-05 (rank : 66)	NC score	0.516800 (rank : 51)
Query Neighborhood Hits	287	Target Neighborhood Hits	434	Shared Neighborhood Hits	197
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRIM7_HUMAN
θ value	4.1701e-05 (rank : 67)	NC score	0.484356 (rank : 82)
Query Neighborhood Hits	287	Target Neighborhood Hits	336	Shared Neighborhood Hits	177
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

PML_HUMAN
θ value	5.44631e-05 (rank : 68)	NC score	0.397857 (rank : 110)
Query Neighborhood Hits	287	Target Neighborhood Hits	248	Shared Neighborhood Hits	110
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRI13_HUMAN
θ value	5.44631e-05 (rank : 69)	NC score	0.626838 (rank : 22)
Query Neighborhood Hits	287	Target Neighborhood Hits	274	Shared Neighborhood Hits	164
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI16_MOUSE
θ value	5.44631e-05 (rank : 70)	NC score	0.503191 (rank : 62)
Query Neighborhood Hits	287	Target Neighborhood Hits	196	Shared Neighborhood Hits	113
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI68_MOUSE
θ value	5.44631e-05 (rank : 71)	NC score	0.483670 (rank : 83)
Query Neighborhood Hits	287	Target Neighborhood Hits	356	Shared Neighborhood Hits	191
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI13_MOUSE
θ value	9.29e-05 (rank : 72)	NC score	0.626444 (rank : 23)
Query Neighborhood Hits	287	Target Neighborhood Hits	282	Shared Neighborhood Hits	167
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI65_MOUSE
θ value	9.29e-05 (rank : 73)	NC score	0.503661 (rank : 61)
Query Neighborhood Hits	287	Target Neighborhood Hits	340	Shared Neighborhood Hits	182
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM3_HUMAN
θ value	9.29e-05 (rank : 74)	NC score	0.583832 (rank : 34)
Query Neighborhood Hits	287	Target Neighborhood Hits	357	Shared Neighborhood Hits	177
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI14_MOUSE
θ value	0.000121331 (rank : 75)	NC score	0.533439 (rank : 46)
Query Neighborhood Hits	287	Target Neighborhood Hits	137	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI22_HUMAN
θ value	0.000121331 (rank : 76)	NC score	0.511152 (rank : 52)
Query Neighborhood Hits	287	Target Neighborhood Hits	396	Shared Neighborhood Hits	193
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI26_HUMAN
θ value	0.000121331 (rank : 77)	NC score	0.502943 (rank : 64)
Query Neighborhood Hits	287	Target Neighborhood Hits	335	Shared Neighborhood Hits	189
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI34_HUMAN
θ value	0.000158464 (rank : 78)	NC score	0.509324 (rank : 55)
Query Neighborhood Hits	287	Target Neighborhood Hits	416	Shared Neighborhood Hits	189
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRIM6_MOUSE
θ value	0.000158464 (rank : 79)	NC score	0.481779 (rank : 86)
Query Neighborhood Hits	287	Target Neighborhood Hits	451	Shared Neighborhood Hits	195
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM6_HUMAN
θ value	0.00020696 (rank : 80)	NC score	0.485764 (rank : 81)
Query Neighborhood Hits	287	Target Neighborhood Hits	412	Shared Neighborhood Hits	192
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM5_HUMAN
θ value	0.000270298 (rank : 81)	NC score	0.497942 (rank : 67)
Query Neighborhood Hits	287	Target Neighborhood Hits	424	Shared Neighborhood Hits	192
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

MEFV_MOUSE
θ value	0.00035302 (rank : 82)	NC score	0.432888 (rank : 100)
Query Neighborhood Hits	287	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI25_MOUSE
θ value	0.00035302 (rank : 83)	NC score	0.595207 (rank : 31)
Query Neighborhood Hits	287	Target Neighborhood Hits	446	Shared Neighborhood Hits	202
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI37_HUMAN
θ value	0.00035302 (rank : 84)	NC score	0.489855 (rank : 74)
Query Neighborhood Hits	287	Target Neighborhood Hits	307	Shared Neighborhood Hits	141
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	0.00035302 (rank : 85)	NC score	0.489605 (rank : 75)
Query Neighborhood Hits	287	Target Neighborhood Hits	316	Shared Neighborhood Hits	142
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI65_HUMAN
θ value	0.00035302 (rank : 86)	NC score	0.541930 (rank : 43)
Query Neighborhood Hits	287	Target Neighborhood Hits	330	Shared Neighborhood Hits	187
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI12_MOUSE
θ value	0.000461057 (rank : 87)	NC score	0.527714 (rank : 48)
Query Neighborhood Hits	287	Target Neighborhood Hits	387	Shared Neighborhood Hits	184
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

UHRF2_MOUSE
θ value	0.000461057 (rank : 88)	NC score	0.300924 (rank : 136)
Query Neighborhood Hits	287	Target Neighborhood Hits	275	Shared Neighborhood Hits	141
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

PML_MOUSE
θ value	0.000602161 (rank : 89)	NC score	0.407516 (rank : 106)
Query Neighborhood Hits	287	Target Neighborhood Hits	246	Shared Neighborhood Hits	121
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI10_MOUSE
θ value	0.000602161 (rank : 90)	NC score	0.493820 (rank : 72)
Query Neighborhood Hits	287	Target Neighborhood Hits	285	Shared Neighborhood Hits	181
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

UHRF2_HUMAN
θ value	0.000602161 (rank : 91)	NC score	0.299363 (rank : 137)
Query Neighborhood Hits	287	Target Neighborhood Hits	269	Shared Neighborhood Hits	141
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

TRI60_HUMAN
θ value	0.000786445 (rank : 92)	NC score	0.495752 (rank : 69)
Query Neighborhood Hits	287	Target Neighborhood Hits	357	Shared Neighborhood Hits	196
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRIM4_HUMAN
θ value	0.000786445 (rank : 93)	NC score	0.506495 (rank : 56)
Query Neighborhood Hits	287	Target Neighborhood Hits	321	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI31_HUMAN
θ value	0.00102713 (rank : 94)	NC score	0.563791 (rank : 38)
Query Neighborhood Hits	287	Target Neighborhood Hits	299	Shared Neighborhood Hits	187
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI26_MOUSE
θ value	0.00134147 (rank : 95)	NC score	0.487558 (rank : 79)
Query Neighborhood Hits	287	Target Neighborhood Hits	339	Shared Neighborhood Hits	187
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRIM2_HUMAN
θ value	0.00175202 (rank : 96)	NC score	0.570520 (rank : 36)
Query Neighborhood Hits	287	Target Neighborhood Hits	330	Shared Neighborhood Hits	170
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.00175202 (rank : 97)	NC score	0.568092 (rank : 37)
Query Neighborhood Hits	287	Target Neighborhood Hits	331	Shared Neighborhood Hits	168
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

ZN313_HUMAN
θ value	0.00175202 (rank : 98)	NC score	0.404308 (rank : 107)
Query Neighborhood Hits	287	Target Neighborhood Hits	264	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

SPRY4_MOUSE
θ value	0.00228821 (rank : 99)	NC score	0.442263 (rank : 99)
Query Neighborhood Hits	287	Target Neighborhood Hits	82	Shared Neighborhood Hits	70
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI40_HUMAN
θ value	0.00228821 (rank : 100)	NC score	0.467242 (rank : 92)
Query Neighborhood Hits	287	Target Neighborhood Hits	279	Shared Neighborhood Hits	157
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

RING1_HUMAN
θ value	0.00298849 (rank : 101)	NC score	0.333498 (rank : 119)
Query Neighborhood Hits	287	Target Neighborhood Hits	219	Shared Neighborhood Hits	125
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.00298849 (rank : 102)	NC score	0.328921 (rank : 121)
Query Neighborhood Hits	287	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI10_HUMAN
θ value	0.00390308 (rank : 103)	NC score	0.495064 (rank : 70)
Query Neighborhood Hits	287	Target Neighborhood Hits	315	Shared Neighborhood Hits	186
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

BRCA1_MOUSE
θ value	0.00509761 (rank : 104)	NC score	0.358515 (rank : 116)
Query Neighborhood Hits	287	Target Neighborhood Hits	436	Shared Neighborhood Hits	152
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RNF39_HUMAN
θ value	0.00509761 (rank : 105)	NC score	0.461915 (rank : 95)
Query Neighborhood Hits	287	Target Neighborhood Hits	200	Shared Neighborhood Hits	153
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

ZN313_MOUSE
θ value	0.00509761 (rank : 106)	NC score	0.414170 (rank : 105)
Query Neighborhood Hits	287	Target Neighborhood Hits	273	Shared Neighborhood Hits	148
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

BRCA1_HUMAN
θ value	0.00665767 (rank : 107)	NC score	0.360359 (rank : 115)
Query Neighborhood Hits	287	Target Neighborhood Hits	381	Shared Neighborhood Hits	149
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRI52_HUMAN
θ value	0.00665767 (rank : 108)	NC score	0.516984 (rank : 50)
Query Neighborhood Hits	287	Target Neighborhood Hits	213	Shared Neighborhood Hits	164
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI68_HUMAN
θ value	0.00665767 (rank : 109)	NC score	0.469251 (rank : 91)
Query Neighborhood Hits	287	Target Neighborhood Hits	267	Shared Neighborhood Hits	176
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI60_MOUSE
θ value	0.0113563 (rank : 110)	NC score	0.467098 (rank : 93)
Query Neighborhood Hits	287	Target Neighborhood Hits	240	Shared Neighborhood Hits	160
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

RING2_HUMAN
θ value	0.0148317 (rank : 111)	NC score	0.311267 (rank : 127)
Query Neighborhood Hits	287	Target Neighborhood Hits	201	Shared Neighborhood Hits	122
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.0148317 (rank : 112)	NC score	0.311316 (rank : 126)
Query Neighborhood Hits	287	Target Neighborhood Hits	199	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

EPHA7_HUMAN
θ value	0.0193708 (rank : 113)	NC score	0.015390 (rank : 345)
Query Neighborhood Hits	287	Target Neighborhood Hits	1053	Shared Neighborhood Hits	32
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
θ value	0.0193708 (rank : 114)	NC score	0.014896 (rank : 346)
Query Neighborhood Hits	287	Target Neighborhood Hits	1025	Shared Neighborhood Hits	32
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

TITIN_HUMAN
θ value	0.0193708 (rank : 115)	NC score	0.028408 (rank : 325)
Query Neighborhood Hits	287	Target Neighborhood Hits	2923	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRI35_MOUSE
θ value	0.0193708 (rank : 116)	NC score	0.489040 (rank : 76)
Query Neighborhood Hits	287	Target Neighborhood Hits	465	Shared Neighborhood Hits	196
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI49_HUMAN
θ value	0.0193708 (rank : 117)	NC score	0.425435 (rank : 102)
Query Neighborhood Hits	287	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRAF2_HUMAN
θ value	0.0330416 (rank : 118)	NC score	0.145988 (rank : 200)
Query Neighborhood Hits	287	Target Neighborhood Hits	402	Shared Neighborhood Hits	118
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

BSPRY_HUMAN
θ value	0.0431538 (rank : 119)	NC score	0.404011 (rank : 108)
Query Neighborhood Hits	287	Target Neighborhood Hits	115	Shared Neighborhood Hits	89
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

MEFV_HUMAN
θ value	0.0431538 (rank : 120)	NC score	0.402163 (rank : 109)
Query Neighborhood Hits	287	Target Neighborhood Hits	431	Shared Neighborhood Hits	126
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

RNF41_HUMAN
θ value	0.0563607 (rank : 121)	NC score	0.308358 (rank : 129)
Query Neighborhood Hits	287	Target Neighborhood Hits	226	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.0563607 (rank : 122)	NC score	0.306922 (rank : 131)
Query Neighborhood Hits	287	Target Neighborhood Hits	224	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RO52_MOUSE
θ value	0.0563607 (rank : 123)	NC score	0.456958 (rank : 96)
Query Neighborhood Hits	287	Target Neighborhood Hits	360	Shared Neighborhood Hits	183
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI35_HUMAN
θ value	0.0563607 (rank : 124)	NC score	0.482294 (rank : 84)
Query Neighborhood Hits	287	Target Neighborhood Hits	382	Shared Neighborhood Hits	192
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

LNX2_MOUSE
θ value	0.0736092 (rank : 125)	NC score	0.198259 (rank : 176)
Query Neighborhood Hits	287	Target Neighborhood Hits	407	Shared Neighborhood Hits	135
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TFE2_MOUSE
θ value	0.0736092 (rank : 126)	NC score	0.033278 (rank : 308)
Query Neighborhood Hits	287	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

TRI43_HUMAN
θ value	0.0736092 (rank : 127)	NC score	0.463429 (rank : 94)
Query Neighborhood Hits	287	Target Neighborhood Hits	341	Shared Neighborhood Hits	185
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

LNX2_HUMAN
θ value	0.0961366 (rank : 128)	NC score	0.199229 (rank : 174)
Query Neighborhood Hits	287	Target Neighborhood Hits	389	Shared Neighborhood Hits	133
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

CP250_MOUSE
θ value	0.125558 (rank : 129)	NC score	0.046712 (rank : 290)
Query Neighborhood Hits	287	Target Neighborhood Hits	1583	Shared Neighborhood Hits	94
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

RN168_HUMAN
θ value	0.125558 (rank : 130)	NC score	0.382285 (rank : 113)
Query Neighborhood Hits	287	Target Neighborhood Hits	370	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF26_HUMAN
θ value	0.125558 (rank : 131)	NC score	0.140396 (rank : 206)
Query Neighborhood Hits	287	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

TRI48_HUMAN
θ value	0.125558 (rank : 132)	NC score	0.423658 (rank : 103)
Query Neighborhood Hits	287	Target Neighborhood Hits	192	Shared Neighborhood Hits	151
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

CLUS_HUMAN
θ value	0.163984 (rank : 133)	NC score	0.048114 (rank : 287)
Query Neighborhood Hits	287	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P10909, P11380, P11381, Q7Z5B9	Gene names	CLU
Domain Architecture
Description	Clusterin precursor (Complement-associated protein SP-40,40) (Complement cytolysis inhibitor) (CLI) (NA1/NA2) (Apolipoprotein J) (Apo-J) (Testosterone-repressed prostate message 2) (TRPM-2) [Contains: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)].

RAD18_HUMAN
θ value	0.163984 (rank : 134)	NC score	0.288316 (rank : 144)
Query Neighborhood Hits	287	Target Neighborhood Hits	284	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RN168_MOUSE
θ value	0.163984 (rank : 135)	NC score	0.365671 (rank : 114)
Query Neighborhood Hits	287	Target Neighborhood Hits	440	Shared Neighborhood Hits	155
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SPRY4_HUMAN
θ value	0.163984 (rank : 136)	NC score	0.423270 (rank : 104)
Query Neighborhood Hits	287	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BT1A1_HUMAN
θ value	0.21417 (rank : 137)	NC score	0.305623 (rank : 133)
Query Neighborhood Hits	287	Target Neighborhood Hits	322	Shared Neighborhood Hits	78
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

RAD18_MOUSE
θ value	0.21417 (rank : 138)	NC score	0.307812 (rank : 130)
Query Neighborhood Hits	287	Target Neighborhood Hits	230	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

HOME1_HUMAN
θ value	0.279714 (rank : 139)	NC score	0.031817 (rank : 311)
Query Neighborhood Hits	287	Target Neighborhood Hits	564	Shared Neighborhood Hits	46
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

TRAF2_MOUSE
θ value	0.279714 (rank : 140)	NC score	0.135588 (rank : 209)
Query Neighborhood Hits	287	Target Neighborhood Hits	394	Shared Neighborhood Hits	115
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

UHRF1_HUMAN
θ value	0.279714 (rank : 141)	NC score	0.241271 (rank : 162)
Query Neighborhood Hits	287	Target Neighborhood Hits	272	Shared Neighborhood Hits	141
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

BEGIN_HUMAN
θ value	0.365318 (rank : 142)	NC score	0.055621 (rank : 270)
Query Neighborhood Hits	287	Target Neighborhood Hits	454	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

PZRN3_HUMAN
θ value	0.365318 (rank : 143)	NC score	0.157255 (rank : 196)
Query Neighborhood Hits	287	Target Neighborhood Hits	461	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.365318 (rank : 144)	NC score	0.157420 (rank : 195)
Query Neighborhood Hits	287	Target Neighborhood Hits	447	Shared Neighborhood Hits	134
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RNF8_HUMAN
θ value	0.365318 (rank : 145)	NC score	0.303882 (rank : 135)
Query Neighborhood Hits	287	Target Neighborhood Hits	622	Shared Neighborhood Hits	175
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	0.365318 (rank : 146)	NC score	0.312898 (rank : 125)
Query Neighborhood Hits	287	Target Neighborhood Hits	618	Shared Neighborhood Hits	179
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRAF4_HUMAN
θ value	0.365318 (rank : 147)	NC score	0.171971 (rank : 188)
Query Neighborhood Hits	287	Target Neighborhood Hits	373	Shared Neighborhood Hits	124
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

UHRF1_MOUSE
θ value	0.365318 (rank : 148)	NC score	0.226860 (rank : 165)
Query Neighborhood Hits	287	Target Neighborhood Hits	278	Shared Neighborhood Hits	138
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

BIRC8_HUMAN
θ value	0.47712 (rank : 149)	NC score	0.119217 (rank : 216)
Query Neighborhood Hits	287	Target Neighborhood Hits	121	Shared Neighborhood Hits	74
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BT3A3_HUMAN
θ value	0.47712 (rank : 150)	NC score	0.294944 (rank : 140)
Query Neighborhood Hits	287	Target Neighborhood Hits	233	Shared Neighborhood Hits	78
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

CENPE_HUMAN
θ value	0.47712 (rank : 151)	NC score	0.037623 (rank : 299)
Query Neighborhood Hits	287	Target Neighborhood Hits	2060	Shared Neighborhood Hits	102
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ERMAP_HUMAN
θ value	0.47712 (rank : 152)	NC score	0.324448 (rank : 123)
Query Neighborhood Hits	287	Target Neighborhood Hits	155	Shared Neighborhood Hits	73
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

GOGA4_HUMAN
θ value	0.47712 (rank : 153)	NC score	0.045022 (rank : 292)
Query Neighborhood Hits	287	Target Neighborhood Hits	2034	Shared Neighborhood Hits	111
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

LNX1_MOUSE
θ value	0.47712 (rank : 154)	NC score	0.186031 (rank : 182)
Query Neighborhood Hits	287	Target Neighborhood Hits	377	Shared Neighborhood Hits	128
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RAI14_HUMAN
θ value	0.47712 (rank : 155)	NC score	0.028926 (rank : 323)
Query Neighborhood Hits	287	Target Neighborhood Hits	1367	Shared Neighborhood Hits	71
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

BEGIN_MOUSE
θ value	0.62314 (rank : 156)	NC score	0.054614 (rank : 272)
Query Neighborhood Hits	287	Target Neighborhood Hits	383	Shared Neighborhood Hits	38
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

MIB1_HUMAN
θ value	0.62314 (rank : 157)	NC score	0.057892 (rank : 262)
Query Neighborhood Hits	287	Target Neighborhood Hits	470	Shared Neighborhood Hits	86
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.62314 (rank : 158)	NC score	0.057519 (rank : 264)
Query Neighborhood Hits	287	Target Neighborhood Hits	471	Shared Neighborhood Hits	86
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RNF31_MOUSE
θ value	0.62314 (rank : 159)	NC score	0.035528 (rank : 302)
Query Neighborhood Hits	287	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

ZN283_HUMAN
θ value	0.62314 (rank : 160)	NC score	-0.004418 (rank : 373)
Query Neighborhood Hits	287	Target Neighborhood Hits	760	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N7M2	Gene names	ZNF283
Domain Architecture	No domain graphic available
Description	Zinc finger protein 283.

BT1A1_MOUSE
θ value	0.813845 (rank : 161)	NC score	0.306445 (rank : 132)
Query Neighborhood Hits	287	Target Neighborhood Hits	252	Shared Neighborhood Hits	78
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

GOGA1_HUMAN
θ value	0.813845 (rank : 162)	NC score	0.035577 (rank : 301)
Query Neighborhood Hits	287	Target Neighborhood Hits	1222	Shared Neighborhood Hits	72
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

R113B_HUMAN
θ value	0.813845 (rank : 163)	NC score	0.231661 (rank : 164)
Query Neighborhood Hits	287	Target Neighborhood Hits	165	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

BIRC4_HUMAN
θ value	1.06291 (rank : 164)	NC score	0.056065 (rank : 269)
Query Neighborhood Hits	287	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BRE1B_MOUSE
θ value	1.06291 (rank : 165)	NC score	0.083673 (rank : 234)
Query Neighborhood Hits	287	Target Neighborhood Hits	970	Shared Neighborhood Hits	144
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

FNDC3_HUMAN
θ value	1.06291 (rank : 166)	NC score	0.058103 (rank : 261)
Query Neighborhood Hits	287	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FYCO1_HUMAN
θ value	1.06291 (rank : 167)	NC score	0.033744 (rank : 307)
Query Neighborhood Hits	287	Target Neighborhood Hits	1149	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GOGA4_MOUSE
θ value	1.06291 (rank : 168)	NC score	0.044938 (rank : 293)
Query Neighborhood Hits	287	Target Neighborhood Hits	1939	Shared Neighborhood Hits	105
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LNX1_HUMAN
θ value	1.06291 (rank : 169)	NC score	0.185090 (rank : 183)
Query Neighborhood Hits	287	Target Neighborhood Hits	379	Shared Neighborhood Hits	133
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

RN166_HUMAN
θ value	1.06291 (rank : 170)	NC score	0.337907 (rank : 118)
Query Neighborhood Hits	287	Target Neighborhood Hits	240	Shared Neighborhood Hits	133
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	1.06291 (rank : 171)	NC score	0.332390 (rank : 120)
Query Neighborhood Hits	287	Target Neighborhood Hits	248	Shared Neighborhood Hits	139
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRAF6_HUMAN
θ value	1.06291 (rank : 172)	NC score	0.237083 (rank : 163)
Query Neighborhood Hits	287	Target Neighborhood Hits	267	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	1.06291 (rank : 173)	NC score	0.243102 (rank : 161)
Query Neighborhood Hits	287	Target Neighborhood Hits	255	Shared Neighborhood Hits	141
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAF7_HUMAN
θ value	1.06291 (rank : 174)	NC score	0.140705 (rank : 205)
Query Neighborhood Hits	287	Target Neighborhood Hits	482	Shared Neighborhood Hits	126
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	1.06291 (rank : 175)	NC score	0.142496 (rank : 203)
Query Neighborhood Hits	287	Target Neighborhood Hits	470	Shared Neighborhood Hits	125
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI32_HUMAN
θ value	1.06291 (rank : 176)	NC score	0.454938 (rank : 97)
Query Neighborhood Hits	287	Target Neighborhood Hits	264	Shared Neighborhood Hits	146
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

BICD1_MOUSE
θ value	1.38821 (rank : 177)	NC score	0.027375 (rank : 326)
Query Neighborhood Hits	287	Target Neighborhood Hits	837	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BRE1B_HUMAN
θ value	1.38821 (rank : 178)	NC score	0.082251 (rank : 236)
Query Neighborhood Hits	287	Target Neighborhood Hits	1040	Shared Neighborhood Hits	146
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BSPRY_MOUSE
θ value	1.38821 (rank : 179)	NC score	0.391030 (rank : 112)
Query Neighborhood Hits	287	Target Neighborhood Hits	163	Shared Neighborhood Hits	91
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

CF060_HUMAN
θ value	1.38821 (rank : 180)	NC score	0.040332 (rank : 297)
Query Neighborhood Hits	287	Target Neighborhood Hits	1270	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

FYCO1_MOUSE
θ value	1.38821 (rank : 181)	NC score	0.032222 (rank : 310)
Query Neighborhood Hits	287	Target Neighborhood Hits	1059	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

I22RA_HUMAN
θ value	1.38821 (rank : 182)	NC score	0.028680 (rank : 324)
Query Neighborhood Hits	287	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q969J5, Q6UWM1, Q96A41, Q96QR0	Gene names	IL22RA2
Domain Architecture	No domain graphic available
Description	Interleukin-22 receptor alpha-2 chain precursor (IL-22R-alpha-2) (Interleukin 22-binding protein) (IL22BP) (Cytokine receptor family class II member 10) (CRF2-10) (Cytokine receptor family type 2, soluble 1) (CRF2-S1).

MYH11_HUMAN
θ value	1.38821 (rank : 183)	NC score	0.033882 (rank : 306)
Query Neighborhood Hits	287	Target Neighborhood Hits	1806	Shared Neighborhood Hits	97
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYOM1_MOUSE
θ value	1.38821 (rank : 184)	NC score	0.046500 (rank : 291)
Query Neighborhood Hits	287	Target Neighborhood Hits	415	Shared Neighborhood Hits	40
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

RFWD2_HUMAN
θ value	1.38821 (rank : 185)	NC score	0.215901 (rank : 169)
Query Neighborhood Hits	287	Target Neighborhood Hits	518	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	1.38821 (rank : 186)	NC score	0.216077 (rank : 168)
Query Neighborhood Hits	287	Target Neighborhood Hits	535	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RUFY1_HUMAN
θ value	1.38821 (rank : 187)	NC score	0.034615 (rank : 305)
Query Neighborhood Hits	287	Target Neighborhood Hits	848	Shared Neighborhood Hits	66
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

TRI32_MOUSE
θ value	1.38821 (rank : 188)	NC score	0.452896 (rank : 98)
Query Neighborhood Hits	287	Target Neighborhood Hits	271	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

BIRC7_HUMAN
θ value	1.81305 (rank : 189)	NC score	0.193359 (rank : 178)
Query Neighborhood Hits	287	Target Neighborhood Hits	185	Shared Neighborhood Hits	119
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CENPF_HUMAN
θ value	1.81305 (rank : 190)	NC score	0.047624 (rank : 289)
Query Neighborhood Hits	287	Target Neighborhood Hits	1932	Shared Neighborhood Hits	109
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

EP15_MOUSE
θ value	1.81305 (rank : 191)	NC score	0.030513 (rank : 320)
Query Neighborhood Hits	287	Target Neighborhood Hits	820	Shared Neighborhood Hits	55
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

HOMEZ_HUMAN
θ value	1.81305 (rank : 192)	NC score	0.025509 (rank : 328)
Query Neighborhood Hits	287	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

MYH10_HUMAN
θ value	1.81305 (rank : 193)	NC score	0.030911 (rank : 318)
Query Neighborhood Hits	287	Target Neighborhood Hits	1620	Shared Neighborhood Hits	92
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	1.81305 (rank : 194)	NC score	0.031227 (rank : 315)
Query Neighborhood Hits	287	Target Neighborhood Hits	1612	Shared Neighborhood Hits	89
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PCGF6_MOUSE
θ value	1.81305 (rank : 195)	NC score	0.157679 (rank : 194)
Query Neighborhood Hits	287	Target Neighborhood Hits	163	Shared Neighborhood Hits	103
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

R113A_HUMAN
θ value	1.81305 (rank : 196)	NC score	0.189105 (rank : 179)
Query Neighborhood Hits	287	Target Neighborhood Hits	177	Shared Neighborhood Hits	99
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RTP3_MOUSE
θ value	1.81305 (rank : 197)	NC score	0.017857 (rank : 341)
Query Neighborhood Hits	287	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SDK1_MOUSE
θ value	1.81305 (rank : 198)	NC score	0.024687 (rank : 329)
Query Neighborhood Hits	287	Target Neighborhood Hits	495	Shared Neighborhood Hits	35
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

CHFR_MOUSE
θ value	2.36792 (rank : 199)	NC score	0.264541 (rank : 155)
Query Neighborhood Hits	287	Target Neighborhood Hits	264	Shared Neighborhood Hits	134
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

EPHB4_MOUSE
θ value	2.36792 (rank : 200)	NC score	0.008138 (rank : 360)
Query Neighborhood Hits	287	Target Neighborhood Hits	1013	Shared Neighborhood Hits	28
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

FNDC3_MOUSE
θ value	2.36792 (rank : 201)	NC score	0.051725 (rank : 276)
Query Neighborhood Hits	287	Target Neighborhood Hits	207	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

GOGB1_HUMAN
θ value	2.36792 (rank : 202)	NC score	0.049022 (rank : 286)
Query Neighborhood Hits	287	Target Neighborhood Hits	2297	Shared Neighborhood Hits	122
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

M4K4_HUMAN
θ value	2.36792 (rank : 203)	NC score	0.004542 (rank : 368)
Query Neighborhood Hits	287	Target Neighborhood Hits	1589	Shared Neighborhood Hits	62
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MYH9_HUMAN
θ value	2.36792 (rank : 204)	NC score	0.032338 (rank : 309)
Query Neighborhood Hits	287	Target Neighborhood Hits	1762	Shared Neighborhood Hits	93
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	2.36792 (rank : 205)	NC score	0.031783 (rank : 312)
Query Neighborhood Hits	287	Target Neighborhood Hits	1829	Shared Neighborhood Hits	95
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYOM1_HUMAN
θ value	2.36792 (rank : 206)	NC score	0.047852 (rank : 288)
Query Neighborhood Hits	287	Target Neighborhood Hits	405	Shared Neighborhood Hits	40
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NEO1_HUMAN
θ value	2.36792 (rank : 207)	NC score	0.022455 (rank : 335)
Query Neighborhood Hits	287	Target Neighborhood Hits	530	Shared Neighborhood Hits	40
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

RKHD1_HUMAN
θ value	2.36792 (rank : 208)	NC score	0.110785 (rank : 218)
Query Neighborhood Hits	287	Target Neighborhood Hits	163	Shared Neighborhood Hits	59
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

TUFT1_MOUSE
θ value	2.36792 (rank : 209)	NC score	0.030912 (rank : 317)
Query Neighborhood Hits	287	Target Neighborhood Hits	732	Shared Neighborhood Hits	48
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

BT3A1_HUMAN
θ value	3.0926 (rank : 210)	NC score	0.291989 (rank : 142)
Query Neighborhood Hits	287	Target Neighborhood Hits	229	Shared Neighborhood Hits	79
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

CHFR_HUMAN
θ value	3.0926 (rank : 211)	NC score	0.263455 (rank : 157)
Query Neighborhood Hits	287	Target Neighborhood Hits	255	Shared Neighborhood Hits	133
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

EPHA5_MOUSE
θ value	3.0926 (rank : 212)	NC score	0.013396 (rank : 351)
Query Neighborhood Hits	287	Target Neighborhood Hits	950	Shared Neighborhood Hits	32
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHB2_HUMAN
θ value	3.0926 (rank : 213)	NC score	0.010462 (rank : 354)
Query Neighborhood Hits	287	Target Neighborhood Hits	983	Shared Neighborhood Hits	31
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	3.0926 (rank : 214)	NC score	0.010446 (rank : 355)
Query Neighborhood Hits	287	Target Neighborhood Hits	982	Shared Neighborhood Hits	31
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

LIPB1_MOUSE
θ value	3.0926 (rank : 215)	NC score	0.023312 (rank : 333)
Query Neighborhood Hits	287	Target Neighborhood Hits	727	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MUC5B_HUMAN
θ value	3.0926 (rank : 216)	NC score	0.010193 (rank : 358)
Query Neighborhood Hits	287	Target Neighborhood Hits	1020	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYOM2_HUMAN
θ value	3.0926 (rank : 217)	NC score	0.049703 (rank : 285)
Query Neighborhood Hits	287	Target Neighborhood Hits	341	Shared Neighborhood Hits	35
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

RBBP6_HUMAN
θ value	3.0926 (rank : 218)	NC score	0.124928 (rank : 214)
Query Neighborhood Hits	287	Target Neighborhood Hits	1135	Shared Neighborhood Hits	114
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	3.0926 (rank : 219)	NC score	0.138656 (rank : 207)
Query Neighborhood Hits	287	Target Neighborhood Hits	1014	Shared Neighborhood Hits	113
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RNF31_HUMAN
θ value	3.0926 (rank : 220)	NC score	0.031367 (rank : 314)
Query Neighborhood Hits	287	Target Neighborhood Hits	110	Shared Neighborhood Hits	17
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

ZFYV1_MOUSE
θ value	3.0926 (rank : 221)	NC score	0.031485 (rank : 313)
Query Neighborhood Hits	287	Target Neighborhood Hits	153	Shared Neighborhood Hits	16
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ZN687_MOUSE
θ value	3.0926 (rank : 222)	NC score	-0.001038 (rank : 371)
Query Neighborhood Hits	287	Target Neighborhood Hits	913	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ARI2_HUMAN
θ value	4.03905 (rank : 223)	NC score	0.062156 (rank : 257)
Query Neighborhood Hits	287	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

BIRC4_MOUSE
θ value	4.03905 (rank : 224)	NC score	0.051023 (rank : 277)
Query Neighborhood Hits	287	Target Neighborhood Hits	89	Shared Neighborhood Hits	43
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

CP250_HUMAN
θ value	4.03905 (rank : 225)	NC score	0.042469 (rank : 295)
Query Neighborhood Hits	287	Target Neighborhood Hits	1805	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CROCC_HUMAN
θ value	4.03905 (rank : 226)	NC score	0.031191 (rank : 316)
Query Neighborhood Hits	287	Target Neighborhood Hits	1409	Shared Neighborhood Hits	79
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DJC16_MOUSE
θ value	4.03905 (rank : 227)	NC score	0.004185 (rank : 369)
Query Neighborhood Hits	287	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TN4, Q811G1, Q8BHI2	Gene names	Dnajc16, Kiaa0962
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 16 precursor.

EPHB4_HUMAN
θ value	4.03905 (rank : 228)	NC score	0.007528 (rank : 363)
Query Neighborhood Hits	287	Target Neighborhood Hits	1056	Shared Neighborhood Hits	29
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

K0226_HUMAN
θ value	4.03905 (rank : 229)	NC score	0.014689 (rank : 347)
Query Neighborhood Hits	287	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

MNAB_HUMAN
θ value	4.03905 (rank : 230)	NC score	0.136103 (rank : 208)
Query Neighborhood Hits	287	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	4.03905 (rank : 231)	NC score	0.134979 (rank : 210)
Query Neighborhood Hits	287	Target Neighborhood Hits	231	Shared Neighborhood Hits	95
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MYH11_MOUSE
θ value	4.03905 (rank : 232)	NC score	0.030194 (rank : 321)
Query Neighborhood Hits	287	Target Neighborhood Hits	1777	Shared Neighborhood Hits	92
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NEO1_MOUSE
θ value	4.03905 (rank : 233)	NC score	0.023405 (rank : 332)
Query Neighborhood Hits	287	Target Neighborhood Hits	523	Shared Neighborhood Hits	40
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

PCGF6_HUMAN
θ value	4.03905 (rank : 234)	NC score	0.150530 (rank : 198)
Query Neighborhood Hits	287	Target Neighborhood Hits	178	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PZRN4_HUMAN
θ value	4.03905 (rank : 235)	NC score	0.147895 (rank : 199)
Query Neighborhood Hits	287	Target Neighborhood Hits	438	Shared Neighborhood Hits	135
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RC3H1_HUMAN
θ value	4.03905 (rank : 236)	NC score	0.158865 (rank : 193)
Query Neighborhood Hits	287	Target Neighborhood Hits	433	Shared Neighborhood Hits	119
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	4.03905 (rank : 237)	NC score	0.165956 (rank : 191)
Query Neighborhood Hits	287	Target Neighborhood Hits	244	Shared Neighborhood Hits	112
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RN123_HUMAN
θ value	4.03905 (rank : 238)	NC score	0.082366 (rank : 235)
Query Neighborhood Hits	287	Target Neighborhood Hits	175	Shared Neighborhood Hits	90
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

ZN408_HUMAN
θ value	4.03905 (rank : 239)	NC score	-0.004140 (rank : 372)
Query Neighborhood Hits	287	Target Neighborhood Hits	775	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

ABCAD_HUMAN
θ value	5.27518 (rank : 240)	NC score	0.003063 (rank : 370)
Query Neighborhood Hits	287	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

BIRC2_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.070150 (rank : 247)
Query Neighborhood Hits	287	Target Neighborhood Hits	142	Shared Neighborhood Hits	76
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC3_MOUSE
θ value	5.27518 (rank : 242)	NC score	0.057710 (rank : 263)
Query Neighborhood Hits	287	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

CA065_HUMAN
θ value	5.27518 (rank : 243)	NC score	0.030868 (rank : 319)
Query Neighborhood Hits	287	Target Neighborhood Hits	469	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CN004_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.036014 (rank : 300)
Query Neighborhood Hits	287	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

CN004_MOUSE
θ value	5.27518 (rank : 245)	NC score	0.035037 (rank : 303)
Query Neighborhood Hits	287	Target Neighborhood Hits	105	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

CTRO_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.012796 (rank : 352)
Query Neighborhood Hits	287	Target Neighborhood Hits	2344	Shared Neighborhood Hits	98
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GOGA3_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.027260 (rank : 327)
Query Neighborhood Hits	287	Target Neighborhood Hits	1317	Shared Neighborhood Hits	73
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

ICAM5_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.006781 (rank : 366)
Query Neighborhood Hits	287	Target Neighborhood Hits	276	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

K1C10_MOUSE
θ value	5.27518 (rank : 249)	NC score	0.007136 (rank : 364)
Query Neighborhood Hits	287	Target Neighborhood Hits	466	Shared Neighborhood Hits	37
SwissProt Accessions	P02535, P08731, Q8BUX3, Q8BV09, Q8BVU3, Q9CXH6, Q9JKB4	Gene names	Krt10, Krt1-10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) (56 kDa cytokeratin) (Keratin, type I cytoskeletal 59 kDa).

MIB2_HUMAN
θ value	5.27518 (rank : 250)	NC score	0.042624 (rank : 294)
Query Neighborhood Hits	287	Target Neighborhood Hits	438	Shared Neighborhood Hits	84
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
θ value	5.27518 (rank : 251)	NC score	0.039139 (rank : 298)
Query Neighborhood Hits	287	Target Neighborhood Hits	409	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PCNT_MOUSE
θ value	5.27518 (rank : 252)	NC score	0.030129 (rank : 322)
Query Neighborhood Hits	287	Target Neighborhood Hits	1207	Shared Neighborhood Hits	76
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RN141_HUMAN
θ value	5.27518 (rank : 253)	NC score	0.198246 (rank : 177)
Query Neighborhood Hits	287	Target Neighborhood Hits	199	Shared Neighborhood Hits	111
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	5.27518 (rank : 254)	NC score	0.198380 (rank : 175)
Query Neighborhood Hits	287	Target Neighborhood Hits	200	Shared Neighborhood Hits	112
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

ZN567_HUMAN
θ value	5.27518 (rank : 255)	NC score	-0.005754 (rank : 374)
Query Neighborhood Hits	287	Target Neighborhood Hits	769	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N184, Q6N044	Gene names	ZNF567
Domain Architecture	No domain graphic available
Description	Zinc finger protein 567.

BARD1_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.074722 (rank : 244)
Query Neighborhood Hits	287	Target Neighborhood Hits	411	Shared Neighborhood Hits	85
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BIRC2_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.061286 (rank : 258)
Query Neighborhood Hits	287	Target Neighborhood Hits	137	Shared Neighborhood Hits	69
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BTNL9_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.278123 (rank : 149)
Query Neighborhood Hits	287	Target Neighborhood Hits	125	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CTRO_HUMAN
θ value	6.88961 (rank : 259)	NC score	0.010200 (rank : 357)
Query Neighborhood Hits	287	Target Neighborhood Hits	2092	Shared Neighborhood Hits	81
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EPHA3_HUMAN
θ value	6.88961 (rank : 260)	NC score	0.010378 (rank : 356)
Query Neighborhood Hits	287	Target Neighborhood Hits	1005	Shared Neighborhood Hits	30
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EVC_HUMAN
θ value	6.88961 (rank : 261)	NC score	0.019411 (rank : 339)
Query Neighborhood Hits	287	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

MYLIP_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.040850 (rank : 296)
Query Neighborhood Hits	287	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

OBSL1_HUMAN
θ value	6.88961 (rank : 263)	NC score	0.011740 (rank : 353)
Query Neighborhood Hits	287	Target Neighborhood Hits	354	Shared Neighborhood Hits	19
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

PEX10_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.283192 (rank : 147)
Query Neighborhood Hits	287	Target Neighborhood Hits	255	Shared Neighborhood Hits	132
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PF21A_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.062596 (rank : 254)
Query Neighborhood Hits	287	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

RN123_MOUSE
θ value	6.88961 (rank : 266)	NC score	0.081621 (rank : 239)
Query Neighborhood Hits	287	Target Neighborhood Hits	174	Shared Neighborhood Hits	92
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

SDK2_HUMAN
θ value	6.88961 (rank : 267)	NC score	0.018478 (rank : 340)
Query Neighborhood Hits	287	Target Neighborhood Hits	495	Shared Neighborhood Hits	34
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	6.88961 (rank : 268)	NC score	0.015911 (rank : 343)
Query Neighborhood Hits	287	Target Neighborhood Hits	480	Shared Neighborhood Hits	30
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

STX16_MOUSE
θ value	6.88961 (rank : 269)	NC score	0.006152 (rank : 367)
Query Neighborhood Hits	287	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVI5	Gene names	Stx16
Domain Architecture	No domain graphic available
Description	Syntaxin-16.

ZFN2B_HUMAN
θ value	6.88961 (rank : 270)	NC score	0.022091 (rank : 337)
Query Neighborhood Hits	287	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WV99, Q8NB98	Gene names	ZFAND2B
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 2B.

ZFN2B_MOUSE
θ value	6.88961 (rank : 271)	NC score	0.023726 (rank : 331)
Query Neighborhood Hits	287	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q91X58, Q9D0W4	Gene names	Zfand2b
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 2B.

ZFY27_HUMAN
θ value	6.88961 (rank : 272)	NC score	0.014492 (rank : 348)
Query Neighborhood Hits	287	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

CN045_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.022130 (rank : 336)
Query Neighborhood Hits	287	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

CTGE6_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.022055 (rank : 338)
Query Neighborhood Hits	287	Target Neighborhood Hits	650	Shared Neighborhood Hits	53
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

EPHA4_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.007742 (rank : 362)
Query Neighborhood Hits	287	Target Neighborhood Hits	975	Shared Neighborhood Hits	29
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.007776 (rank : 361)
Query Neighborhood Hits	287	Target Neighborhood Hits	982	Shared Neighborhood Hits	29
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA5_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.013734 (rank : 349)
Query Neighborhood Hits	287	Target Neighborhood Hits	1009	Shared Neighborhood Hits	32
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

GOGA2_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.023920 (rank : 330)
Query Neighborhood Hits	287	Target Neighborhood Hits	856	Shared Neighborhood Hits	53
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

K2C1B_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.008756 (rank : 359)
Query Neighborhood Hits	287	Target Neighborhood Hits	542	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

MLL4_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.013400 (rank : 350)
Query Neighborhood Hits	287	Target Neighborhood Hits	722	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PEX26_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.015692 (rank : 344)
Query Neighborhood Hits	287	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z412, Q7Z413, Q7Z414, Q7Z415, Q7Z416, Q96B12, Q9NWQ0, Q9NXU0	Gene names	PEX26
Domain Architecture
Description	Peroxisome assembly protein 26 (Peroxin-26).

PRRT1_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.006892 (rank : 365)
Query Neighborhood Hits	287	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

RPGR1_HUMAN
θ value	8.99809 (rank : 283)	NC score	0.023038 (rank : 334)
Query Neighborhood Hits	287	Target Neighborhood Hits	578	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SDK1_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.017632 (rank : 342)
Query Neighborhood Hits	287	Target Neighborhood Hits	511	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ZFYV1_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.034842 (rank : 304)
Query Neighborhood Hits	287	Target Neighborhood Hits	166	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZN436_HUMAN
θ value	8.99809 (rank : 286)	NC score	-0.006553 (rank : 376)
Query Neighborhood Hits	287	Target Neighborhood Hits	756	Shared Neighborhood Hits	11
SwissProt Accessions	Q9C0F3, Q658I9	Gene names	ZNF436, KIAA1710
Domain Architecture
Description	Zinc finger protein 436.

ZNF12_HUMAN
θ value	8.99809 (rank : 287)	NC score	-0.006120 (rank : 375)
Query Neighborhood Hits	287	Target Neighborhood Hits	779	Shared Neighborhood Hits	14
SwissProt Accessions	P17014, Q9ULZ6	Gene names	ZNF12, GIOT3, KOX3, ZNF325
Domain Architecture	No domain graphic available
Description	Zinc finger protein 12 (Zinc finger protein KOX3) (Zinc finger protein 325) (Gonadotropin-inducible transcription repressor 3) (GIOT-3).

AIRE_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.063635 (rank : 252)
Query Neighborhood Hits	287	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.062219 (rank : 256)
Query Neighborhood Hits	287	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AMFR2_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.087456 (rank : 231)
Query Neighborhood Hits	287	Target Neighborhood Hits	219	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.087191 (rank : 232)
Query Neighborhood Hits	287	Target Neighborhood Hits	208	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ARI2_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.057346 (rank : 265)
Query Neighborhood Hits	287	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

BARD1_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.077953 (rank : 243)
Query Neighborhood Hits	287	Target Neighborhood Hits	427	Shared Neighborhood Hits	85
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.050182 (rank : 281)
Query Neighborhood Hits	287	Target Neighborhood Hits	693	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.052505 (rank : 275)
Query Neighborhood Hits	287	Target Neighborhood Hits	780	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.050328 (rank : 280)
Query Neighborhood Hits	287	Target Neighborhood Hits	744	Shared Neighborhood Hits	30
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.050394 (rank : 279)
Query Neighborhood Hits	287	Target Neighborhood Hits	803	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BFAR_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.275590 (rank : 151)
Query Neighborhood Hits	287	Target Neighborhood Hits	222	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.257660 (rank : 158)
Query Neighborhood Hits	287	Target Neighborhood Hits	232	Shared Neighborhood Hits	118
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BIRC3_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.062559 (rank : 255)
Query Neighborhood Hits	287	Target Neighborhood Hits	133	Shared Neighborhood Hits	70
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BRE1A_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.065392 (rank : 249)
Query Neighborhood Hits	287	Target Neighborhood Hits	1071	Shared Neighborhood Hits	141
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.062814 (rank : 253)
Query Neighborhood Hits	287	Target Neighborhood Hits	1025	Shared Neighborhood Hits	137
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BT2A1_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.268119 (rank : 154)
Query Neighborhood Hits	287	Target Neighborhood Hits	185	Shared Neighborhood Hits	73
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.283297 (rank : 146)
Query Neighborhood Hits	287	Target Neighborhood Hits	191	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.263466 (rank : 156)
Query Neighborhood Hits	287	Target Neighborhood Hits	195	Shared Neighborhood Hits	69
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.276233 (rank : 150)
Query Neighborhood Hits	287	Target Neighborhood Hits	143	Shared Neighborhood Hits	71
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.257290 (rank : 159)
Query Neighborhood Hits	287	Target Neighborhood Hits	177	Shared Neighborhood Hits	73
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

CBLB_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.079107 (rank : 242)
Query Neighborhood Hits	287	Target Neighborhood Hits	261	Shared Neighborhood Hits	114
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.079560 (rank : 241)
Query Neighborhood Hits	287	Target Neighborhood Hits	277	Shared Neighborhood Hits	114
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.081727 (rank : 237)
Query Neighborhood Hits	287	Target Neighborhood Hits	173	Shared Neighborhood Hits	98
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.085414 (rank : 233)
Query Neighborhood Hits	287	Target Neighborhood Hits	186	Shared Neighborhood Hits	103
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.081652 (rank : 238)
Query Neighborhood Hits	287	Target Neighborhood Hits	353	Shared Neighborhood Hits	114
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.080272 (rank : 240)
Query Neighborhood Hits	287	Target Neighborhood Hits	426	Shared Neighborhood Hits	119
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CM007_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.103061 (rank : 226)
Query Neighborhood Hits	287	Target Neighborhood Hits	422	Shared Neighborhood Hits	105
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.118852 (rank : 217)
Query Neighborhood Hits	287	Target Neighborhood Hits	416	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DTX3L_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.099745 (rank : 227)
Query Neighborhood Hits	287	Target Neighborhood Hits	187	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.177739 (rank : 187)
Query Neighborhood Hits	287	Target Neighborhood Hits	198	Shared Neighborhood Hits	117
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.184785 (rank : 184)
Query Neighborhood Hits	287	Target Neighborhood Hits	202	Shared Neighborhood Hits	122
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

ERMAP_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.294955 (rank : 139)
Query Neighborhood Hits	287	Target Neighborhood Hits	231	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

FSD1L_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.292249 (rank : 141)
Query Neighborhood Hits	287	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.342066 (rank : 117)
Query Neighborhood Hits	287	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

LY10_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.072199 (rank : 246)
Query Neighborhood Hits	287	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MGRN1_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.094266 (rank : 229)
Query Neighborhood Hits	287	Target Neighborhood Hits	192	Shared Neighborhood Hits	74
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.095918 (rank : 228)
Query Neighborhood Hits	287	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

NHLC1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.107155 (rank : 219)
Query Neighborhood Hits	287	Target Neighborhood Hits	91	Shared Neighborhood Hits	51
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.129491 (rank : 212)
Query Neighborhood Hits	287	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCGF2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.105057 (rank : 220)
Query Neighborhood Hits	287	Target Neighborhood Hits	222	Shared Neighborhood Hits	91
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.103153 (rank : 225)
Query Neighborhood Hits	287	Target Neighborhood Hits	213	Shared Neighborhood Hits	90
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.104165 (rank : 223)
Query Neighborhood Hits	287	Target Neighborhood Hits	161	Shared Neighborhood Hits	92
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.104524 (rank : 221)
Query Neighborhood Hits	287	Target Neighborhood Hits	163	Shared Neighborhood Hits	91
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PF21A_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.057301 (rank : 266)
Query Neighborhood Hits	287	Target Neighborhood Hits	285	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PJA1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.050018 (rank : 284)
Query Neighborhood Hits	287	Target Neighborhood Hits	159	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PKCB1_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.053392 (rank : 274)
Query Neighborhood Hits	287	Target Neighborhood Hits	488	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RAG1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.199762 (rank : 173)
Query Neighborhood Hits	287	Target Neighborhood Hits	203	Shared Neighborhood Hits	114
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.200740 (rank : 172)
Query Neighborhood Hits	287	Target Neighborhood Hits	189	Shared Neighborhood Hits	115
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RFPL1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.310486 (rank : 128)
Query Neighborhood Hits	287	Target Neighborhood Hits	119	Shared Neighborhood Hits	99
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.304930 (rank : 134)
Query Neighborhood Hits	287	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.316359 (rank : 124)
Query Neighborhood Hits	287	Target Neighborhood Hits	134	Shared Neighborhood Hits	109
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RN125_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.270766 (rank : 153)
Query Neighborhood Hits	287	Target Neighborhood Hits	230	Shared Neighborhood Hits	130
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.273230 (rank : 152)
Query Neighborhood Hits	287	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN146_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.213937 (rank : 170)
Query Neighborhood Hits	287	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.212407 (rank : 171)
Query Neighborhood Hits	287	Target Neighborhood Hits	161	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN152_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.142085 (rank : 204)
Query Neighborhood Hits	287	Target Neighborhood Hits	107	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.143506 (rank : 202)
Query Neighborhood Hits	287	Target Neighborhood Hits	109	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN169_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.225652 (rank : 166)
Query Neighborhood Hits	287	Target Neighborhood Hits	203	Shared Neighborhood Hits	99
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.254322 (rank : 160)
Query Neighborhood Hits	287	Target Neighborhood Hits	126	Shared Neighborhood Hits	98
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.217274 (rank : 167)
Query Neighborhood Hits	287	Target Neighborhood Hits	119	Shared Neighborhood Hits	93
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.186709 (rank : 180)
Query Neighborhood Hits	287	Target Neighborhood Hits	213	Shared Neighborhood Hits	118
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.186482 (rank : 181)
Query Neighborhood Hits	287	Target Neighborhood Hits	211	Shared Neighborhood Hits	118
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF32_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.056405 (rank : 268)
Query Neighborhood Hits	287	Target Neighborhood Hits	133	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF34_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.063761 (rank : 251)
Query Neighborhood Hits	287	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.064399 (rank : 250)
Query Neighborhood Hits	287	Target Neighborhood Hits	160	Shared Neighborhood Hits	68
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF4_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.170352 (rank : 189)
Query Neighborhood Hits	287	Target Neighborhood Hits	212	Shared Neighborhood Hits	115
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.167823 (rank : 190)
Query Neighborhood Hits	287	Target Neighborhood Hits	212	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.181000 (rank : 185)
Query Neighborhood Hits	287	Target Neighborhood Hits	206	Shared Neighborhood Hits	120
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.179449 (rank : 186)
Query Neighborhood Hits	287	Target Neighborhood Hits	206	Shared Neighborhood Hits	119
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

SIAH2_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.050160 (rank : 282)
Query Neighborhood Hits	287	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SMRA3_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.159762 (rank : 192)
Query Neighborhood Hits	287	Target Neighborhood Hits	265	Shared Neighborhood Hits	133
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.150632 (rank : 197)
Query Neighborhood Hits	287	Target Neighborhood Hits	267	Shared Neighborhood Hits	130
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SP110_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.054401 (rank : 273)
Query Neighborhood Hits	287	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TOPRS_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.123229 (rank : 215)
Query Neighborhood Hits	287	Target Neighborhood Hits	286	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.126060 (rank : 213)
Query Neighborhood Hits	287	Target Neighborhood Hits	263	Shared Neighborhood Hits	91
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF3_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.103902 (rank : 224)
Query Neighborhood Hits	287	Target Neighborhood Hits	463	Shared Neighborhood Hits	129
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.104304 (rank : 222)
Query Neighborhood Hits	287	Target Neighborhood Hits	476	Shared Neighborhood Hits	133
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.093447 (rank : 230)
Query Neighborhood Hits	287	Target Neighborhood Hits	338	Shared Neighborhood Hits	89
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.130123 (rank : 211)
Query Neighborhood Hits	287	Target Neighborhood Hits	396	Shared Neighborhood Hits	128
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.144450 (rank : 201)
Query Neighborhood Hits	287	Target Neighborhood Hits	355	Shared Neighborhood Hits	125
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAIP_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.066319 (rank : 248)
Query Neighborhood Hits	287	Target Neighborhood Hits	780	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.060104 (rank : 259)
Query Neighborhood Hits	287	Target Neighborhood Hits	745	Shared Neighborhood Hits	83
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

UB7I3_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.056485 (rank : 267)
Query Neighborhood Hits	287	Target Neighborhood Hits	136	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.072833 (rank : 245)
Query Neighborhood Hits	287	Target Neighborhood Hits	131	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

ZN179_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.325913 (rank : 122)
Query Neighborhood Hits	287	Target Neighborhood Hits	178	Shared Neighborhood Hits	113
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN363_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.050070 (rank : 283)
Query Neighborhood Hits	287	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.050497 (rank : 278)
Query Neighborhood Hits	287	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.059841 (rank : 260)
Query Neighborhood Hits	287	Target Neighborhood Hits	151	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.055219 (rank : 271)
Query Neighborhood Hits	287	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

TRI46_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	287	Target Neighborhood Hits	287	Shared Neighborhood Hits	287
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.998211 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	287	Target Neighborhood Hits	291	Shared Neighborhood Hits	274
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI36_MOUSE
NC score	0.953432 (rank : 3)	θ value	9.76035e-180 (rank : 3)
Query Neighborhood Hits	287	Target Neighborhood Hits	266	Shared Neighborhood Hits	175
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI36_HUMAN
NC score	0.951992 (rank : 4)	θ value	2.93876e-176 (rank : 4)
Query Neighborhood Hits	287	Target Neighborhood Hits	282	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRIM1_MOUSE
NC score	0.855246 (rank : 5)	θ value	2.25659e-51 (rank : 6)
Query Neighborhood Hits	287	Target Neighborhood Hits	361	Shared Neighborhood Hits	205
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM1_HUMAN
NC score	0.853788 (rank : 6)	θ value	1.36902e-48 (rank : 8)
Query Neighborhood Hits	287	Target Neighborhood Hits	345	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI18_MOUSE
NC score	0.852339 (rank : 7)	θ value	4.54686e-52 (rank : 5)
Query Neighborhood Hits	287	Target Neighborhood Hits	292	Shared Neighborhood Hits	191
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI18_HUMAN
NC score	0.847000 (rank : 8)	θ value	1.61718e-49 (rank : 7)
Query Neighborhood Hits	287	Target Neighborhood Hits	307	Shared Neighborhood Hits	193
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRIM9_HUMAN
NC score	0.836074 (rank : 9)	θ value	2.26182e-43 (rank : 9)
Query Neighborhood Hits	287	Target Neighborhood Hits	294	Shared Neighborhood Hits	181
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
NC score	0.826826 (rank : 10)	θ value	1.3722e-40 (rank : 10)
Query Neighborhood Hits	287	Target Neighborhood Hits	274	Shared Neighborhood Hits	174
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI63_MOUSE
NC score	0.823202 (rank : 11)	θ value	2.50655e-34 (rank : 12)
Query Neighborhood Hits	287	Target Neighborhood Hits	240	Shared Neighborhood Hits	170
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI54_MOUSE
NC score	0.819725 (rank : 12)	θ value	1.24399e-33 (rank : 14)
Query Neighborhood Hits	287	Target Neighborhood Hits	197	Shared Neighborhood Hits	154
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
NC score	0.817346 (rank : 13)	θ value	8.61488e-35 (rank : 11)
Query Neighborhood Hits	287	Target Neighborhood Hits	292	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI54_HUMAN
NC score	0.815603 (rank : 14)	θ value	5.584e-34 (rank : 13)
Query Neighborhood Hits	287	Target Neighborhood Hits	209	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI63_HUMAN
NC score	0.805727 (rank : 15)	θ value	2.27234e-27 (rank : 15)
Query Neighborhood Hits	287	Target Neighborhood Hits	298	Shared Neighborhood Hits	171
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM8_MOUSE
NC score	0.689585 (rank : 16)	θ value	1.16975e-15 (rank : 18)
Query Neighborhood Hits	287	Target Neighborhood Hits	674	Shared Neighborhood Hits	201
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI42_MOUSE
NC score	0.689263 (rank : 17)	θ value	2.27762e-19 (rank : 16)
Query Neighborhood Hits	287	Target Neighborhood Hits	316	Shared Neighborhood Hits	136
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_HUMAN
NC score	0.686415 (rank : 18)	θ value	5.60996e-18 (rank : 17)
Query Neighborhood Hits	287	Target Neighborhood Hits	283	Shared Neighborhood Hits	135
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRIM8_HUMAN
NC score	0.685802 (rank : 19)	θ value	2.43908e-13 (rank : 19)
Query Neighborhood Hits	287	Target Neighborhood Hits	650	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI59_MOUSE
NC score	0.670305 (rank : 20)	θ value	1.47974e-10 (rank : 25)
Query Neighborhood Hits	287	Target Neighborhood Hits	292	Shared Neighborhood Hits	170
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.667460 (rank : 21)	θ value	6.64225e-11 (rank : 23)
Query Neighborhood Hits	287	Target Neighborhood Hits	307	Shared Neighborhood Hits	167
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI13_HUMAN
NC score	0.626838 (rank : 22)	θ value	5.44631e-05 (rank : 69)
Query Neighborhood Hits	287	Target Neighborhood Hits	274	Shared Neighborhood Hits	164
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
NC score	0.626444 (rank : 23)	θ value	9.29e-05 (rank : 72)
Query Neighborhood Hits	287	Target Neighborhood Hits	282	Shared Neighborhood Hits	167
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI45_MOUSE
NC score	0.625119 (rank : 24)	θ value	1.58096e-12 (rank : 21)
Query Neighborhood Hits	287	Target Neighborhood Hits	155	Shared Neighborhood Hits	103
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI45_HUMAN
NC score	0.623894 (rank : 25)	θ value	7.09661e-13 (rank : 20)
Query Neighborhood Hits	287	Target Neighborhood Hits	155	Shared Neighborhood Hits	115
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI56_MOUSE
NC score	0.615855 (rank : 26)	θ value	2.36244e-08 (rank : 34)
Query Neighborhood Hits	287	Target Neighborhood Hits	255	Shared Neighborhood Hits	157
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI47_MOUSE
NC score	0.608411 (rank : 27)	θ value	2.52405e-10 (rank : 26)
Query Neighborhood Hits	287	Target Neighborhood Hits	295	Shared Neighborhood Hits	175
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI25_HUMAN
NC score	0.602288 (rank : 28)	θ value	1.69304e-06 (rank : 49)
Query Neighborhood Hits	287	Target Neighborhood Hits	472	Shared Neighborhood Hits	198
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI47_HUMAN
NC score	0.601502 (rank : 29)	θ value	1.74796e-11 (rank : 22)
Query Neighborhood Hits	287	Target Neighborhood Hits	286	Shared Neighborhood Hits	179
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRIM3_MOUSE
NC score	0.596519 (rank : 30)	θ value	2.88788e-06 (rank : 52)
Query Neighborhood Hits	287	Target Neighborhood Hits	351	Shared Neighborhood Hits	171
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI25_MOUSE
NC score	0.595207 (rank : 31)	θ value	0.00035302 (rank : 83)
Query Neighborhood Hits	287	Target Neighborhood Hits	446	Shared Neighborhood Hits	202
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI56_HUMAN
NC score	0.592975 (rank : 32)	θ value	2.88788e-06 (rank : 51)
Query Neighborhood Hits	287	Target Neighborhood Hits	339	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI73_HUMAN
NC score	0.585320 (rank : 33)	θ value	1.87187e-05 (rank : 63)
Query Neighborhood Hits	287	Target Neighborhood Hits	258	Shared Neighborhood Hits	186
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRIM3_HUMAN
NC score	0.583832 (rank : 34)	θ value	9.29e-05 (rank : 74)
Query Neighborhood Hits	287	Target Neighborhood Hits	357	Shared Neighborhood Hits	177
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI74_HUMAN
NC score	0.583488 (rank : 35)	θ value	1.87187e-05 (rank : 64)
Query Neighborhood Hits	287	Target Neighborhood Hits	249	Shared Neighborhood Hits	179
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM2_HUMAN
NC score	0.570520 (rank : 36)	θ value	0.00175202 (rank : 96)
Query Neighborhood Hits	287	Target Neighborhood Hits	330	Shared Neighborhood Hits	170
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.568092 (rank : 37)	θ value	0.00175202 (rank : 97)
Query Neighborhood Hits	287	Target Neighborhood Hits	331	Shared Neighborhood Hits	168
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI31_HUMAN
NC score	0.563791 (rank : 38)	θ value	0.00102713 (rank : 94)
Query Neighborhood Hits	287	Target Neighborhood Hits	299	Shared Neighborhood Hits	187
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI29_MOUSE
NC score	0.553853 (rank : 39)	θ value	6.21693e-09 (rank : 28)
Query Neighborhood Hits	287	Target Neighborhood Hits	306	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI50_MOUSE
NC score	0.550222 (rank : 40)	θ value	1.29631e-06 (rank : 47)
Query Neighborhood Hits	287	Target Neighborhood Hits	326	Shared Neighborhood Hits	193
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_HUMAN
NC score	0.550005 (rank : 41)	θ value	3.41135e-07 (rank : 44)
Query Neighborhood Hits	287	Target Neighborhood Hits	294	Shared Neighborhood Hits	185
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI29_HUMAN
NC score	0.547244 (rank : 42)	θ value	2.36244e-08 (rank : 33)
Query Neighborhood Hits	287	Target Neighborhood Hits	273	Shared Neighborhood Hits	107
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI65_HUMAN
NC score	0.541930 (rank : 43)	θ value	0.00035302 (rank : 86)
Query Neighborhood Hits	287	Target Neighborhood Hits	330	Shared Neighborhood Hits	187
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI14_HUMAN
NC score	0.539307 (rank : 44)	θ value	8.40245e-06 (rank : 59)
Query Neighborhood Hits	287	Target Neighborhood Hits	143	Shared Neighborhood Hits	108
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI62_MOUSE
NC score	0.533770 (rank : 45)	θ value	8.97725e-08 (rank : 41)
Query Neighborhood Hits	287	Target Neighborhood Hits	478	Shared Neighborhood Hits	191
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI14_MOUSE
NC score	0.533439 (rank : 46)	θ value	0.000121331 (rank : 75)
Query Neighborhood Hits	287	Target Neighborhood Hits	137	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI62_HUMAN
NC score	0.532816 (rank : 47)	θ value	1.99992e-07 (rank : 42)
Query Neighborhood Hits	287	Target Neighborhood Hits	584	Shared Neighborhood Hits	199
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI12_MOUSE
NC score	0.527714 (rank : 48)	θ value	0.000461057 (rank : 87)
Query Neighborhood Hits	287	Target Neighborhood Hits	387	Shared Neighborhood Hits	184
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI41_HUMAN
NC score	0.519786 (rank : 49)	θ value	5.26297e-08 (rank : 36)
Query Neighborhood Hits	287	Target Neighborhood Hits	349	Shared Neighborhood Hits	184
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI52_HUMAN
NC score	0.516984 (rank : 50)	θ value	0.00665767 (rank : 108)
Query Neighborhood Hits	287	Target Neighborhood Hits	213	Shared Neighborhood Hits	164
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI30_MOUSE
NC score	0.516800 (rank : 51)	θ value	4.1701e-05 (rank : 66)
Query Neighborhood Hits	287	Target Neighborhood Hits	434	Shared Neighborhood Hits	197
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI22_HUMAN
NC score	0.511152 (rank : 52)	θ value	0.000121331 (rank : 76)
Query Neighborhood Hits	287	Target Neighborhood Hits	396	Shared Neighborhood Hits	193
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI17_MOUSE
NC score	0.509888 (rank : 53)	θ value	2.61198e-07 (rank : 43)
Query Neighborhood Hits	287	Target Neighborhood Hits	620	Shared Neighborhood Hits	202
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI39_HUMAN
NC score	0.509353 (rank : 54)	θ value	1.38499e-08 (rank : 31)
Query Neighborhood Hits	287	Target Neighborhood Hits	693	Shared Neighborhood Hits	207
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI34_HUMAN
NC score	0.509324 (rank : 55)	θ value	0.000158464 (rank : 78)
Query Neighborhood Hits	287	Target Neighborhood Hits	416	Shared Neighborhood Hits	189
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRIM4_HUMAN
NC score	0.506495 (rank : 56)	θ value	0.000786445 (rank : 93)
Query Neighborhood Hits	287	Target Neighborhood Hits	321	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI39_MOUSE
NC score	0.505617 (rank : 57)	θ value	4.0297e-08 (rank : 35)
Query Neighborhood Hits	287	Target Neighborhood Hits	691	Shared Neighborhood Hits	207
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM7_MOUSE
NC score	0.505603 (rank : 58)	θ value	2.21117e-06 (rank : 50)
Query Neighborhood Hits	287	Target Neighborhood Hits	358	Shared Neighborhood Hits	181
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI17_HUMAN
NC score	0.505210 (rank : 59)	θ value	8.97725e-08 (rank : 40)
Query Neighborhood Hits	287	Target Neighborhood Hits	318	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI44_MOUSE
NC score	0.505179 (rank : 60)	θ value	6.43352e-06 (rank : 58)
Query Neighborhood Hits	287	Target Neighborhood Hits	327	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI65_MOUSE
NC score	0.503661 (rank : 61)	θ value	9.29e-05 (rank : 73)
Query Neighborhood Hits	287	Target Neighborhood Hits	340	Shared Neighborhood Hits	182
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI16_MOUSE
NC score	0.503191 (rank : 62)	θ value	5.44631e-05 (rank : 70)
Query Neighborhood Hits	287	Target Neighborhood Hits	196	Shared Neighborhood Hits	113
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI15_HUMAN
NC score	0.503091 (rank : 63)	θ value	8.67504e-11 (rank : 24)
Query Neighborhood Hits	287	Target Neighborhood Hits	395	Shared Neighborhood Hits	185
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI26_HUMAN
NC score	0.502943 (rank : 64)	θ value	0.000121331 (rank : 77)
Query Neighborhood Hits	287	Target Neighborhood Hits	335	Shared Neighborhood Hits	189
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI44_HUMAN
NC score	0.498614 (rank : 65)	θ value	4.92598e-06 (rank : 57)
Query Neighborhood Hits	287	Target Neighborhood Hits	393	Shared Neighborhood Hits	106
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI11_HUMAN
NC score	0.498417 (rank : 66)	θ value	1.06045e-08 (rank : 30)
Query Neighborhood Hits	287	Target Neighborhood Hits	316	Shared Neighborhood Hits	179
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRIM5_HUMAN
NC score	0.497942 (rank : 67)	θ value	0.000270298 (rank : 81)
Query Neighborhood Hits	287	Target Neighborhood Hits	424	Shared Neighborhood Hits	192
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI27_HUMAN
NC score	0.496890 (rank : 68)	θ value	4.92598e-06 (rank : 56)
Query Neighborhood Hits	287	Target Neighborhood Hits	273	Shared Neighborhood Hits	176
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI60_HUMAN
NC score	0.495752 (rank : 69)	θ value	0.000786445 (rank : 92)
Query Neighborhood Hits	287	Target Neighborhood Hits	357	Shared Neighborhood Hits	196
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI10_HUMAN
NC score	0.495064 (rank : 70)	θ value	0.00390308 (rank : 103)
Query Neighborhood Hits	287	Target Neighborhood Hits	315	Shared Neighborhood Hits	186
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI27_MOUSE
NC score	0.494150 (rank : 71)	θ value	8.40245e-06 (rank : 60)
Query Neighborhood Hits	287	Target Neighborhood Hits	261	Shared Neighborhood Hits	169
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI10_MOUSE
NC score	0.493820 (rank : 72)	θ value	0.000602161 (rank : 90)
Query Neighborhood Hits	287	Target Neighborhood Hits	285	Shared Neighborhood Hits	181
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI11_MOUSE
NC score	0.491440 (rank : 73)	θ value	2.36244e-08 (rank : 32)
Query Neighborhood Hits	287	Target Neighborhood Hits	329	Shared Neighborhood Hits	181
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI37_HUMAN
NC score	0.489855 (rank : 74)	θ value	0.00035302 (rank : 84)
Query Neighborhood Hits	287	Target Neighborhood Hits	307	Shared Neighborhood Hits	141
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.489605 (rank : 75)	θ value	0.00035302 (rank : 85)
Query Neighborhood Hits	287	Target Neighborhood Hits	316	Shared Neighborhood Hits	142
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI35_MOUSE
NC score	0.489040 (rank : 76)	θ value	0.0193708 (rank : 116)
Query Neighborhood Hits	287	Target Neighborhood Hits	465	Shared Neighborhood Hits	196
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI38_HUMAN
NC score	0.488662 (rank : 77)	θ value	7.59969e-07 (rank : 45)
Query Neighborhood Hits	287	Target Neighborhood Hits	373	Shared Neighborhood Hits	186
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI16_HUMAN
NC score	0.488290 (rank : 78)	θ value	1.87187e-05 (rank : 62)
Query Neighborhood Hits	287	Target Neighborhood Hits	231	Shared Neighborhood Hits	112
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI26_MOUSE
NC score	0.487558 (rank : 79)	θ value	0.00134147 (rank : 95)
Query Neighborhood Hits	287	Target Neighborhood Hits	339	Shared Neighborhood Hits	187
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TIF1B_HUMAN
NC score	0.487218 (rank : 80)	θ value	3.77169e-06 (rank : 53)
Query Neighborhood Hits	287	Target Neighborhood Hits	312	Shared Neighborhood Hits	109
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRIM6_HUMAN
NC score	0.485764 (rank : 81)	θ value	0.00020696 (rank : 80)
Query Neighborhood Hits	287	Target Neighborhood Hits	412	Shared Neighborhood Hits	192
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM7_HUMAN
NC score	0.484356 (rank : 82)	θ value	4.1701e-05 (rank : 67)
Query Neighborhood Hits	287	Target Neighborhood Hits	336	Shared Neighborhood Hits	177
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI68_MOUSE
NC score	0.483670 (rank : 83)	θ value	5.44631e-05 (rank : 71)
Query Neighborhood Hits	287	Target Neighborhood Hits	356	Shared Neighborhood Hits	191
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI35_HUMAN
NC score	0.482294 (rank : 84)	θ value	0.0563607 (rank : 124)
Query Neighborhood Hits	287	Target Neighborhood Hits	382	Shared Neighborhood Hits	192
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI34_MOUSE
NC score	0.481865 (rank : 85)	θ value	3.19293e-05 (rank : 65)
Query Neighborhood Hits	287	Target Neighborhood Hits	332	Shared Neighborhood Hits	176
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRIM6_MOUSE
NC score	0.481779 (rank : 86)	θ value	0.000158464 (rank : 79)
Query Neighborhood Hits	287	Target Neighborhood Hits	451	Shared Neighborhood Hits	195
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TIF1G_HUMAN
NC score	0.481449 (rank : 87)	θ value	8.11959e-09 (rank : 29)
Query Neighborhood Hits	287	Target Neighborhood Hits	410	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1B_MOUSE
NC score	0.480075 (rank : 88)	θ value	3.77169e-06 (rank : 54)
Query Neighborhood Hits	287	Target Neighborhood Hits	276	Shared Neighborhood Hits	106
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

RO52_HUMAN
NC score	0.478209 (rank : 89)	θ value	1.43324e-05 (rank : 61)
Query Neighborhood Hits	287	Target Neighborhood Hits	419	Shared Neighborhood Hits	203
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TIF1G_MOUSE
NC score	0.477630 (rank : 90)	θ value	2.13673e-09 (rank : 27)
Query Neighborhood Hits	287	Target Neighborhood Hits	498	Shared Neighborhood Hits	118
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI68_HUMAN
NC score	0.469251 (rank : 91)	θ value	0.00665767 (rank : 109)
Query Neighborhood Hits	287	Target Neighborhood Hits	267	Shared Neighborhood Hits	176
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI40_HUMAN
NC score	0.467242 (rank : 92)	θ value	0.00228821 (rank : 100)
Query Neighborhood Hits	287	Target Neighborhood Hits	279	Shared Neighborhood Hits	157
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI60_MOUSE
NC score	0.467098 (rank : 93)	θ value	0.0113563 (rank : 110)
Query Neighborhood Hits	287	Target Neighborhood Hits	240	Shared Neighborhood Hits	160
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI43_HUMAN
NC score	0.463429 (rank : 94)	θ value	0.0736092 (rank : 127)
Query Neighborhood Hits	287	Target Neighborhood Hits	341	Shared Neighborhood Hits	185
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

RNF39_HUMAN
NC score	0.461915 (rank : 95)	θ value	0.00509761 (rank : 105)
Query Neighborhood Hits	287	Target Neighborhood Hits	200	Shared Neighborhood Hits	153
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RO52_MOUSE
NC score	0.456958 (rank : 96)	θ value	0.0563607 (rank : 123)
Query Neighborhood Hits	287	Target Neighborhood Hits	360	Shared Neighborhood Hits	183
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI32_HUMAN
NC score	0.454938 (rank : 97)	θ value	1.06291 (rank : 176)
Query Neighborhood Hits	287	Target Neighborhood Hits	264	Shared Neighborhood Hits	146
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.452896 (rank : 98)	θ value	1.38821 (rank : 188)
Query Neighborhood Hits	287	Target Neighborhood Hits	271	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

SPRY4_MOUSE
NC score	0.442263 (rank : 99)	θ value	0.00228821 (rank : 99)
Query Neighborhood Hits	287	Target Neighborhood Hits	82	Shared Neighborhood Hits	70
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

MEFV_MOUSE
NC score	0.432888 (rank : 100)	θ value	0.00035302 (rank : 82)
Query Neighborhood Hits	287	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TIF1A_HUMAN
NC score	0.425610 (rank : 101)	θ value	6.87365e-08 (rank : 37)
Query Neighborhood Hits	287	Target Neighborhood Hits	327	Shared Neighborhood Hits	105
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRI49_HUMAN
NC score	0.425435 (rank : 102)	θ value	0.0193708 (rank : 117)
Query Neighborhood Hits	287	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI48_HUMAN
NC score	0.423658 (rank : 103)	θ value	0.125558 (rank : 132)
Query Neighborhood Hits	287	Target Neighborhood Hits	192	Shared Neighborhood Hits	151
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

SPRY4_HUMAN
NC score	0.423270 (rank : 104)	θ value	0.163984 (rank : 136)
Query Neighborhood Hits	287	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

ZN313_MOUSE
NC score	0.414170 (rank : 105)	θ value	0.00509761 (rank : 106)
Query Neighborhood Hits	287	Target Neighborhood Hits	273	Shared Neighborhood Hits	148
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

PML_MOUSE
NC score	0.407516 (rank : 106)	θ value	0.000602161 (rank : 89)
Query Neighborhood Hits	287	Target Neighborhood Hits	246	Shared Neighborhood Hits	121
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

ZN313_HUMAN
NC score	0.404308 (rank : 107)	θ value	0.00175202 (rank : 98)
Query Neighborhood Hits	287	Target Neighborhood Hits	264	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

BSPRY_HUMAN
NC score	0.404011 (rank : 108)	θ value	0.0431538 (rank : 119)
Query Neighborhood Hits	287	Target Neighborhood Hits	115	Shared Neighborhood Hits	89
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

MEFV_HUMAN
NC score	0.402163 (rank : 109)	θ value	0.0431538 (rank : 120)
Query Neighborhood Hits	287	Target Neighborhood Hits	431	Shared Neighborhood Hits	126
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PML_HUMAN
NC score	0.397857 (rank : 110)	θ value	5.44631e-05 (rank : 68)
Query Neighborhood Hits	287	Target Neighborhood Hits	248	Shared Neighborhood Hits	110
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TIF1A_MOUSE
NC score	0.396044 (rank : 111)	θ value	6.87365e-08 (rank : 38)
Query Neighborhood Hits	287	Target Neighborhood Hits	307	Shared Neighborhood Hits	98
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

BSPRY_MOUSE
NC score	0.391030 (rank : 112)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	287	Target Neighborhood Hits	163	Shared Neighborhood Hits	91
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RN168_HUMAN
NC score	0.382285 (rank : 113)	θ value	0.125558 (rank : 130)
Query Neighborhood Hits	287	Target Neighborhood Hits	370	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
NC score	0.365671 (rank : 114)	θ value	0.163984 (rank : 135)
Query Neighborhood Hits	287	Target Neighborhood Hits	440	Shared Neighborhood Hits	155
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

BRCA1_HUMAN
NC score	0.360359 (rank : 115)	θ value	0.00665767 (rank : 107)
Query Neighborhood Hits	287	Target Neighborhood Hits	381	Shared Neighborhood Hits	149
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
NC score	0.358515 (rank : 116)	θ value	0.00509761 (rank : 104)
Query Neighborhood Hits	287	Target Neighborhood Hits	436	Shared Neighborhood Hits	152
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

FSD1L_MOUSE
NC score	0.342066 (rank : 117)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	287	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

RN166_HUMAN
NC score	0.337907 (rank : 118)	θ value	1.06291 (rank : 170)
Query Neighborhood Hits	287	Target Neighborhood Hits	240	Shared Neighborhood Hits	133
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RING1_HUMAN
NC score	0.333498 (rank : 119)	θ value	0.00298849 (rank : 101)
Query Neighborhood Hits	287	Target Neighborhood Hits	219	Shared Neighborhood Hits	125
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RN166_MOUSE
NC score	0.332390 (rank : 120)	θ value	1.06291 (rank : 171)
Query Neighborhood Hits	287	Target Neighborhood Hits	248	Shared Neighborhood Hits	139
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RING1_MOUSE
NC score	0.328921 (rank : 121)	θ value	0.00298849 (rank : 102)
Query Neighborhood Hits	287	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

ZN179_HUMAN
NC score	0.325913 (rank : 122)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	287	Target Neighborhood Hits	178	Shared Neighborhood Hits	113
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ERMAP_HUMAN
NC score	0.324448 (rank : 123)	θ value	0.47712 (rank : 152)
Query Neighborhood Hits	287	Target Neighborhood Hits	155	Shared Neighborhood Hits	73
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

RFPL3_HUMAN
NC score	0.316359 (rank : 124)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	287	Target Neighborhood Hits	134	Shared Neighborhood Hits	109
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RNF8_MOUSE
NC score	0.312898 (rank : 125)	θ value	0.365318 (rank : 146)
Query Neighborhood Hits	287	Target Neighborhood Hits	618	Shared Neighborhood Hits	179
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RING2_MOUSE
NC score	0.311316 (rank : 126)	θ value	0.0148317 (rank : 112)
Query Neighborhood Hits	287	Target Neighborhood Hits	199	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.311267 (rank : 127)	θ value	0.0148317 (rank : 111)
Query Neighborhood Hits	287	Target Neighborhood Hits	201	Shared Neighborhood Hits	122
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RFPL1_HUMAN
NC score	0.310486 (rank : 128)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	287	Target Neighborhood Hits	119	Shared Neighborhood Hits	99
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RNF41_HUMAN
NC score	0.308358 (rank : 129)	θ value	0.0563607 (rank : 121)
Query Neighborhood Hits	287	Target Neighborhood Hits	226	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RAD18_MOUSE
NC score	0.307812 (rank : 130)	θ value	0.21417 (rank : 138)
Query Neighborhood Hits	287	Target Neighborhood Hits	230	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RNF41_MOUSE
NC score	0.306922 (rank : 131)	θ value	0.0563607 (rank : 122)
Query Neighborhood Hits	287	Target Neighborhood Hits	224	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

BT1A1_MOUSE
NC score	0.306445 (rank : 132)	θ value	0.813845 (rank : 161)
Query Neighborhood Hits	287	Target Neighborhood Hits	252	Shared Neighborhood Hits	78
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_HUMAN
NC score	0.305623 (rank : 133)	θ value	0.21417 (rank : 137)
Query Neighborhood Hits	287	Target Neighborhood Hits	322	Shared Neighborhood Hits	78
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

RFPL2_HUMAN
NC score	0.304930 (rank : 134)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	287	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RNF8_HUMAN
NC score	0.303882 (rank : 135)	θ value	0.365318 (rank : 145)
Query Neighborhood Hits	287	Target Neighborhood Hits	622	Shared Neighborhood Hits	175
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

UHRF2_MOUSE
NC score	0.300924 (rank : 136)	θ value	0.000461057 (rank : 88)
Query Neighborhood Hits	287	Target Neighborhood Hits	275	Shared Neighborhood Hits	141
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

UHRF2_HUMAN
NC score	0.299363 (rank : 137)	θ value	0.000602161 (rank : 91)
Query Neighborhood Hits	287	Target Neighborhood Hits	269	Shared Neighborhood Hits	141
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

TRI66_MOUSE
NC score	0.296486 (rank : 138)	θ value	3.77169e-06 (rank : 55)
Query Neighborhood Hits	287	Target Neighborhood Hits	491	Shared Neighborhood Hits	81
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ERMAP_MOUSE
NC score	0.294955 (rank : 139)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	287	Target Neighborhood Hits	231	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

BT3A3_HUMAN
NC score	0.294944 (rank : 140)	θ value	0.47712 (rank : 150)
Query Neighborhood Hits	287	Target Neighborhood Hits	233	Shared Neighborhood Hits	78
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

FSD1L_HUMAN
NC score	0.292249 (rank : 141)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	287	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

BT3A1_HUMAN
NC score	0.291989 (rank : 142)	θ value	3.0926 (rank : 210)
Query Neighborhood Hits	287	Target Neighborhood Hits	229	Shared Neighborhood Hits	79
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

TRI66_HUMAN
NC score	0.291088 (rank : 143)	θ value	9.92553e-07 (rank : 46)
Query Neighborhood Hits	287	Target Neighborhood Hits	479	Shared Neighborhood Hits	75
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RAD18_HUMAN
NC score	0.288316 (rank : 144)	θ value	0.163984 (rank : 134)
Query Neighborhood Hits	287	Target Neighborhood Hits	284	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

ARD1_MOUSE
NC score	0.287406 (rank : 145)	θ value	1.69304e-06 (rank : 48)
Query Neighborhood Hits	287	Target Neighborhood Hits	573	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

BT2A2_HUMAN
NC score	0.283297 (rank : 146)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	287	Target Neighborhood Hits	191	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

PEX10_HUMAN
NC score	0.283192 (rank : 147)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	287	Target Neighborhood Hits	255	Shared Neighborhood Hits	132
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

ARD1_HUMAN
NC score	0.281648 (rank : 148)	θ value	8.97725e-08 (rank : 39)
Query Neighborhood Hits	287	Target Neighborhood Hits	621	Shared Neighborhood Hits	90
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

BTNL9_HUMAN
NC score	0.278123 (rank : 149)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	287	Target Neighborhood Hits	125	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BTNL3_HUMAN
NC score	0.276233 (rank : 150)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	287	Target Neighborhood Hits	143	Shared Neighborhood Hits	71
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BFAR_HUMAN
NC score	0.275590 (rank : 151)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	287	Target Neighborhood Hits	222	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RN125_MOUSE
NC score	0.273230 (rank : 152)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	287	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN125_HUMAN
NC score	0.270766 (rank : 153)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	287	Target Neighborhood Hits	230	Shared Neighborhood Hits	130
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

BT2A1_HUMAN
NC score	0.268119 (rank : 154)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	287	Target Neighborhood Hits	185	Shared Neighborhood Hits	73
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

CHFR_MOUSE
NC score	0.264541 (rank : 155)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	287	Target Neighborhood Hits	264	Shared Neighborhood Hits	134
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

BT2A3_HUMAN
NC score	0.263466 (rank : 156)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	287	Target Neighborhood Hits	195	Shared Neighborhood Hits	69
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

CHFR_HUMAN
NC score	0.263455 (rank : 157)	θ value	3.0926 (rank : 211)
Query Neighborhood Hits	287	Target Neighborhood Hits	255	Shared Neighborhood Hits	133
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

BFAR_MOUSE
NC score	0.257660 (rank : 158)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	287	Target Neighborhood Hits	232	Shared Neighborhood Hits	118
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BTNL8_HUMAN
NC score	0.257290 (rank : 159)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	287	Target Neighborhood Hits	177	Shared Neighborhood Hits	73
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

RN183_HUMAN
NC score	0.254322 (rank : 160)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	287	Target Neighborhood Hits	126	Shared Neighborhood Hits	98
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRAF6_MOUSE
NC score	0.243102 (rank : 161)	θ value	1.06291 (rank : 173)
Query Neighborhood Hits	287	Target Neighborhood Hits	255	Shared Neighborhood Hits	141
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

UHRF1_HUMAN
NC score	0.241271 (rank : 162)	θ value	0.279714 (rank : 141)
Query Neighborhood Hits	287	Target Neighborhood Hits	272	Shared Neighborhood Hits	141
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

TRAF6_HUMAN
NC score	0.237083 (rank : 163)	θ value	1.06291 (rank : 172)
Query Neighborhood Hits	287	Target Neighborhood Hits	267	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

R113B_HUMAN
NC score	0.231661 (rank : 164)	θ value	0.813845 (rank : 163)
Query Neighborhood Hits	287	Target Neighborhood Hits	165	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

UHRF1_MOUSE
NC score	0.226860 (rank : 165)	θ value	0.365318 (rank : 148)
Query Neighborhood Hits	287	Target Neighborhood Hits	278	Shared Neighborhood Hits	138
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

RN169_HUMAN
NC score	0.225652 (rank : 166)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	287	Target Neighborhood Hits	203	Shared Neighborhood Hits	99
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_MOUSE
NC score	0.217274 (rank : 167)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	287	Target Neighborhood Hits	119	Shared Neighborhood Hits	93
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RFWD2_MOUSE
NC score	0.216077 (rank : 168)	θ value	1.38821 (rank : 186)
Query Neighborhood Hits	287	Target Neighborhood Hits	535	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.215901 (rank : 169)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	287	Target Neighborhood Hits	518	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RN146_HUMAN
NC score	0.213937 (rank : 170)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	287	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.212407 (rank : 171)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	287	Target Neighborhood Hits	161	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RAG1_MOUSE
NC score	0.200740 (rank : 172)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	287	Target Neighborhood Hits	189	Shared Neighborhood Hits	115
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RAG1_HUMAN
NC score	0.199762 (rank : 173)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	287	Target Neighborhood Hits	203	Shared Neighborhood Hits	114
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

LNX2_HUMAN
NC score	0.199229 (rank : 174)	θ value	0.0961366 (rank : 128)
Query Neighborhood Hits	287	Target Neighborhood Hits	389	Shared Neighborhood Hits	133
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RN141_MOUSE
NC score	0.198380 (rank : 175)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	287	Target Neighborhood Hits	200	Shared Neighborhood Hits	112
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

LNX2_MOUSE
NC score	0.198259 (rank : 176)	θ value	0.0736092 (rank : 125)
Query Neighborhood Hits	287	Target Neighborhood Hits	407	Shared Neighborhood Hits	135
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RN141_HUMAN
NC score	0.198246 (rank : 177)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	287	Target Neighborhood Hits	199	Shared Neighborhood Hits	111
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

BIRC7_HUMAN
NC score	0.193359 (rank : 178)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	287	Target Neighborhood Hits	185	Shared Neighborhood Hits	119
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

R113A_HUMAN
NC score	0.189105 (rank : 179)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	287	Target Neighborhood Hits	177	Shared Neighborhood Hits	99
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RN185_HUMAN
NC score	0.186709 (rank : 180)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	287	Target Neighborhood Hits	213	Shared Neighborhood Hits	118
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.186482 (rank : 181)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	287	Target Neighborhood Hits	211	Shared Neighborhood Hits	118
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

LNX1_MOUSE
NC score	0.186031 (rank : 182)	θ value	0.47712 (rank : 154)
Query Neighborhood Hits	287	Target Neighborhood Hits	377	Shared Neighborhood Hits	128
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_HUMAN
NC score	0.185090 (rank : 183)	θ value	1.06291 (rank : 169)
Query Neighborhood Hits	287	Target Neighborhood Hits	379	Shared Neighborhood Hits	133
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

DTX3_MOUSE
NC score	0.184785 (rank : 184)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	287	Target Neighborhood Hits	202	Shared Neighborhood Hits	122
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RNF5_HUMAN
NC score	0.181000 (rank : 185)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	287	Target Neighborhood Hits	206	Shared Neighborhood Hits	120
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.179449 (rank : 186)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	287	Target Neighborhood Hits	206	Shared Neighborhood Hits	119
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

DTX3_HUMAN
NC score	0.177739 (rank : 187)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	287	Target Neighborhood Hits	198	Shared Neighborhood Hits	117
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

TRAF4_HUMAN
NC score	0.171971 (rank : 188)	θ value	0.365318 (rank : 147)
Query Neighborhood Hits	287	Target Neighborhood Hits	373	Shared Neighborhood Hits	124
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

RNF4_HUMAN
NC score	0.170352 (rank : 189)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	287	Target Neighborhood Hits	212	Shared Neighborhood Hits	115
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.167823 (rank : 190)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	287	Target Neighborhood Hits	212	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RC3H1_MOUSE
NC score	0.165956 (rank : 191)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	287	Target Neighborhood Hits	244	Shared Neighborhood Hits	112
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

SMRA3_HUMAN
NC score	0.159762 (rank : 192)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	287	Target Neighborhood Hits	265	Shared Neighborhood Hits	133
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

RC3H1_HUMAN
NC score	0.158865 (rank : 193)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	287	Target Neighborhood Hits	433	Shared Neighborhood Hits	119
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

PCGF6_MOUSE
NC score	0.157679 (rank : 194)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	287	Target Neighborhood Hits	163	Shared Neighborhood Hits	103
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PZRN3_MOUSE
NC score	0.157420 (rank : 195)	θ value	0.365318 (rank : 144)
Query Neighborhood Hits	287	Target Neighborhood Hits	447	Shared Neighborhood Hits	134
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.157255 (rank : 196)	θ value	0.365318 (rank : 143)
Query Neighborhood Hits	287	Target Neighborhood Hits	461	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SMRA3_MOUSE
NC score	0.150632 (rank : 197)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	287	Target Neighborhood Hits	267	Shared Neighborhood Hits	130
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

PCGF6_HUMAN
NC score	0.150530 (rank : 198)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	287	Target Neighborhood Hits	178	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PZRN4_HUMAN
NC score	0.147895 (rank : 199)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	287	Target Neighborhood Hits	438	Shared Neighborhood Hits	135
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRAF2_HUMAN
NC score	0.145988 (rank : 200)	θ value	0.0330416 (rank : 118)
Query Neighborhood Hits	287	Target Neighborhood Hits	402	Shared Neighborhood Hits	118
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF5_MOUSE
NC score	0.144450 (rank : 201)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	287	Target Neighborhood Hits	355	Shared Neighborhood Hits	125
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

RN152_MOUSE
NC score	0.143506 (rank : 202)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	287	Target Neighborhood Hits	109	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TRAF7_MOUSE
NC score	0.142496 (rank : 203)	θ value	1.06291 (rank : 175)
Query Neighborhood Hits	287	Target Neighborhood Hits	470	Shared Neighborhood Hits	125
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

RN152_HUMAN
NC score	0.142085 (rank : 204)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	287	Target Neighborhood Hits	107	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

TRAF7_HUMAN
NC score	0.140705 (rank : 205)	θ value	1.06291 (rank : 174)
Query Neighborhood Hits	287	Target Neighborhood Hits	482	Shared Neighborhood Hits	126
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

RNF26_HUMAN
NC score	0.140396 (rank : 206)	θ value	0.125558 (rank : 131)
Query Neighborhood Hits	287	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RBBP6_MOUSE
NC score	0.138656 (rank : 207)	θ value	3.0926 (rank : 219)
Query Neighborhood Hits	287	Target Neighborhood Hits	1014	Shared Neighborhood Hits	113
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

MNAB_HUMAN
NC score	0.136103 (rank : 208)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	287	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

TRAF2_MOUSE
NC score	0.135588 (rank : 209)	θ value	0.279714 (rank : 140)
Query Neighborhood Hits	287	Target Neighborhood Hits	394	Shared Neighborhood Hits	115
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

MNAB_MOUSE
NC score	0.134979 (rank : 210)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	287	Target Neighborhood Hits	231	Shared Neighborhood Hits	95
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

TRAF5_HUMAN
NC score	0.130123 (rank : 211)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	287	Target Neighborhood Hits	396	Shared Neighborhood Hits	128
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

NHLC1_MOUSE
NC score	0.129491 (rank : 212)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	287	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TOPRS_MOUSE
NC score	0.126060 (rank : 213)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	287	Target Neighborhood Hits	263	Shared Neighborhood Hits	91
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RBBP6_HUMAN
NC score	0.124928 (rank : 214)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	287	Target Neighborhood Hits	1135	Shared Neighborhood Hits	114
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TOPRS_HUMAN
NC score	0.123229 (rank : 215)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	287	Target Neighborhood Hits	286	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

BIRC8_HUMAN
NC score	0.119217 (rank : 216)	θ value	0.47712 (rank : 149)
Query Neighborhood Hits	287	Target Neighborhood Hits	121	Shared Neighborhood Hits	74
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CM007_MOUSE
NC score	0.118852 (rank : 217)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	287	Target Neighborhood Hits	416	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RKHD1_HUMAN
NC score	0.110785 (rank : 218)	θ value	2.36792 (rank : 208)
Query Neighborhood Hits	287	Target Neighborhood Hits	163	Shared Neighborhood Hits	59
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

NHLC1_HUMAN
NC score	0.107155 (rank : 219)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	287	Target Neighborhood Hits	91	Shared Neighborhood Hits	51
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCGF2_HUMAN
NC score	0.105057 (rank : 220)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	287	Target Neighborhood Hits	222	Shared Neighborhood Hits	91
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF4_MOUSE
NC score	0.104524 (rank : 221)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	287	Target Neighborhood Hits	163	Shared Neighborhood Hits	91
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

TRAF3_MOUSE
NC score	0.104304 (rank : 222)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	287	Target Neighborhood Hits	476	Shared Neighborhood Hits	133
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

PCGF4_HUMAN
NC score	0.104165 (rank : 223)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	287	Target Neighborhood Hits	161	Shared Neighborhood Hits	92
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

TRAF3_HUMAN
NC score	0.103902 (rank : 224)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	287	Target Neighborhood Hits	463	Shared Neighborhood Hits	129
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

PCGF2_MOUSE
NC score	0.103153 (rank : 225)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	287	Target Neighborhood Hits	213	Shared Neighborhood Hits	90
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

CM007_HUMAN
NC score	0.103061 (rank : 226)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	287	Target Neighborhood Hits	422	Shared Neighborhood Hits	105
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

DTX3L_HUMAN
NC score	0.099745 (rank : 227)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	287	Target Neighborhood Hits	187	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

MGRN1_MOUSE
NC score	0.095918 (rank : 228)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	287	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MGRN1_HUMAN
NC score	0.094266 (rank : 229)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	287	Target Neighborhood Hits	192	Shared Neighborhood Hits	74
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

TRAF4_MOUSE
NC score	0.093447 (rank : 230)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	287	Target Neighborhood Hits	338	Shared Neighborhood Hits	89
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

AMFR2_HUMAN
NC score	0.087456 (rank : 231)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	287	Target Neighborhood Hits	219	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
NC score	0.087191 (rank : 232)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	287	Target Neighborhood Hits	208	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

CBLC_MOUSE
NC score	0.085414 (rank : 233)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	287	Target Neighborhood Hits	186	Shared Neighborhood Hits	103
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

BRE1B_MOUSE
NC score	0.083673 (rank : 234)	θ value	1.06291 (rank : 165)
Query Neighborhood Hits	287	Target Neighborhood Hits	970	Shared Neighborhood Hits	144
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

RN123_HUMAN
NC score	0.082366 (rank : 235)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	287	Target Neighborhood Hits	175	Shared Neighborhood Hits	90
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

BRE1B_HUMAN
NC score	0.082251 (rank : 236)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	287	Target Neighborhood Hits	1040	Shared Neighborhood Hits	146
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CBLC_HUMAN
NC score	0.081727 (rank : 237)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	287	Target Neighborhood Hits	173	Shared Neighborhood Hits	98
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBL_HUMAN
NC score	0.081652 (rank : 238)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	287	Target Neighborhood Hits	353	Shared Neighborhood Hits	114
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

RN123_MOUSE
NC score	0.081621 (rank : 239)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	287	Target Neighborhood Hits	174	Shared Neighborhood Hits	92
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

CBL_MOUSE
NC score	0.080272 (rank : 240)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	287	Target Neighborhood Hits	426	Shared Neighborhood Hits	119
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBLB_MOUSE
NC score	0.079560 (rank : 241)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	287	Target Neighborhood Hits	277	Shared Neighborhood Hits	114
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.079107 (rank : 242)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	287	Target Neighborhood Hits	261	Shared Neighborhood Hits	114
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

BARD1_HUMAN
NC score	0.077953 (rank : 243)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	287	Target Neighborhood Hits	427	Shared Neighborhood Hits	85
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
NC score	0.074722 (rank : 244)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	287	Target Neighborhood Hits	411	Shared Neighborhood Hits	85
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

UB7I3_MOUSE
NC score	0.072833 (rank : 245)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	287	Target Neighborhood Hits	131	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

LY10_HUMAN
NC score	0.072199 (rank : 246)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	287	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

BIRC2_HUMAN
NC score	0.070150 (rank : 247)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	287	Target Neighborhood Hits	142	Shared Neighborhood Hits	76
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

TRAIP_HUMAN
NC score	0.066319 (rank : 248)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	287	Target Neighborhood Hits	780	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

BRE1A_HUMAN
NC score	0.065392 (rank : 249)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	287	Target Neighborhood Hits	1071	Shared Neighborhood Hits	141
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

RNF34_MOUSE
NC score	0.064399 (rank : 250)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	287	Target Neighborhood Hits	160	Shared Neighborhood Hits	68
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.063761 (rank : 251)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	287	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

AIRE_HUMAN
NC score	0.063635 (rank : 252)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	287	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

BRE1A_MOUSE
NC score	0.062814 (rank : 253)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	287	Target Neighborhood Hits	1025	Shared Neighborhood Hits	137
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

PF21A_HUMAN
NC score	0.062596 (rank : 254)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	287	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

BIRC3_HUMAN
NC score	0.062559 (rank : 255)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	287	Target Neighborhood Hits	133	Shared Neighborhood Hits	70
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

AIRE_MOUSE
NC score	0.062219 (rank : 256)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	287	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ARI2_HUMAN
NC score	0.062156 (rank : 257)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	287	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

BIRC2_MOUSE
NC score	0.061286 (rank : 258)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	287	Target Neighborhood Hits	137	Shared Neighborhood Hits	69
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

TRAIP_MOUSE
NC score	0.060104 (rank : 259)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	287	Target Neighborhood Hits	745	Shared Neighborhood Hits	83
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

ZSWM2_HUMAN
NC score	0.059841 (rank : 260)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	287	Target Neighborhood Hits	151	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

FNDC3_HUMAN
NC score	0.058103 (rank : 261)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	287	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

MIB1_HUMAN
NC score	0.057892 (rank : 262)	θ value	0.62314 (rank : 157)
Query Neighborhood Hits	287	Target Neighborhood Hits	470	Shared Neighborhood Hits	86
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

BIRC3_MOUSE
NC score	0.057710 (rank : 263)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	287	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

MIB1_MOUSE
NC score	0.057519 (rank : 264)	θ value	0.62314 (rank : 158)
Query Neighborhood Hits	287	Target Neighborhood Hits	471	Shared Neighborhood Hits	86
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ARI2_MOUSE
NC score	0.057346 (rank : 265)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	287	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

PF21A_MOUSE
NC score	0.057301 (rank : 266)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	287	Target Neighborhood Hits	285	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

UB7I3_HUMAN
NC score	0.056485 (rank : 267)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	287	Target Neighborhood Hits	136	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RNF32_HUMAN
NC score	0.056405 (rank : 268)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	287	Target Neighborhood Hits	133	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

BIRC4_HUMAN
NC score	0.056065 (rank : 269)	θ value	1.06291 (rank : 164)
Query Neighborhood Hits	287	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BEGIN_HUMAN
NC score	0.055621 (rank : 270)	θ value	0.365318 (rank : 142)
Query Neighborhood Hits	287	Target Neighborhood Hits	454	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

ZSWM2_MOUSE
NC score	0.055219 (rank : 271)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	287	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

BEGIN_MOUSE
NC score	0.054614 (rank : 272)	θ value	0.62314 (rank : 156)
Query Neighborhood Hits	287	Target Neighborhood Hits	383	Shared Neighborhood Hits	38
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

SP110_HUMAN
NC score	0.054401 (rank : 273)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	287	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

PKCB1_HUMAN
NC score	0.053392 (rank : 274)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	287	Target Neighborhood Hits	488	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

BAZ2A_HUMAN
NC score	0.052505 (rank : 275)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	287	Target Neighborhood Hits	780	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

FNDC3_MOUSE
NC score	0.051725 (rank : 276)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	287	Target Neighborhood Hits	207	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

BIRC4_MOUSE
NC score	0.051023 (rank : 277)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	287	Target Neighborhood Hits	89	Shared Neighborhood Hits	43
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

ZN363_MOUSE
NC score	0.050497 (rank : 278)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	287	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

BAZ2B_HUMAN
NC score	0.050394 (rank : 279)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	287	Target Neighborhood Hits	803	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BAZ2A_MOUSE
NC score	0.050328 (rank : 280)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	287	Target Neighborhood Hits	744	Shared Neighborhood Hits	30
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ1A_HUMAN
NC score	0.050182 (rank : 281)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	287	Target Neighborhood Hits	693	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

SIAH2_HUMAN
NC score	0.050160 (rank : 282)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	287	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

ZN363_HUMAN
NC score	0.050070 (rank : 283)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	287	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

PJA1_HUMAN
NC score	0.050018 (rank : 284)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	287	Target Neighborhood Hits	159	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

MYOM2_HUMAN
NC score	0.049703 (rank : 285)	θ value	3.0926 (rank : 217)
Query Neighborhood Hits	287	Target Neighborhood Hits	341	Shared Neighborhood Hits	35
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

GOGB1_HUMAN
NC score	0.049022 (rank : 286)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	287	Target Neighborhood Hits	2297	Shared Neighborhood Hits	122
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CLUS_HUMAN
NC score	0.048114 (rank : 287)	θ value	0.163984 (rank : 133)
Query Neighborhood Hits	287	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P10909, P11380, P11381, Q7Z5B9	Gene names	CLU
Domain Architecture
Description	Clusterin precursor (Complement-associated protein SP-40,40) (Complement cytolysis inhibitor) (CLI) (NA1/NA2) (Apolipoprotein J) (Apo-J) (Testosterone-repressed prostate message 2) (TRPM-2) [Contains: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)].

MYOM1_HUMAN
NC score	0.047852 (rank : 288)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	287	Target Neighborhood Hits	405	Shared Neighborhood Hits	40
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

CENPF_HUMAN
NC score	0.047624 (rank : 289)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	287	Target Neighborhood Hits	1932	Shared Neighborhood Hits	109
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CP250_MOUSE
NC score	0.046712 (rank : 290)	θ value	0.125558 (rank : 129)
Query Neighborhood Hits	287	Target Neighborhood Hits	1583	Shared Neighborhood Hits	94
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MYOM1_MOUSE
NC score	0.046500 (rank : 291)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	287	Target Neighborhood Hits	415	Shared Neighborhood Hits	40
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

GOGA4_HUMAN
NC score	0.045022 (rank : 292)	θ value	0.47712 (rank : 153)
Query Neighborhood Hits	287	Target Neighborhood Hits	2034	Shared Neighborhood Hits	111
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA4_MOUSE
NC score	0.044938 (rank : 293)	θ value	1.06291 (rank : 168)
Query Neighborhood Hits	287	Target Neighborhood Hits	1939	Shared Neighborhood Hits	105
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MIB2_HUMAN
NC score	0.042624 (rank : 294)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	287	Target Neighborhood Hits	438	Shared Neighborhood Hits	84
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CP250_HUMAN
NC score	0.042469 (rank : 295)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	287	Target Neighborhood Hits	1805	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MYLIP_HUMAN
NC score	0.040850 (rank : 296)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	287	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CF060_HUMAN
NC score	0.040332 (rank : 297)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	287	Target Neighborhood Hits	1270	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

MIB2_MOUSE
NC score	0.039139 (rank : 298)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	287	Target Neighborhood Hits	409	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

CENPE_HUMAN
NC score	0.037623 (rank : 299)	θ value	0.47712 (rank : 151)
Query Neighborhood Hits	287	Target Neighborhood Hits	2060	Shared Neighborhood Hits	102
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CN004_HUMAN
NC score	0.036014 (rank : 300)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	287	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

GOGA1_HUMAN
NC score	0.035577 (rank : 301)	θ value	0.813845 (rank : 162)
Query Neighborhood Hits	287	Target Neighborhood Hits	1222	Shared Neighborhood Hits	72
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

RNF31_MOUSE
NC score	0.035528 (rank : 302)	θ value	0.62314 (rank : 159)
Query Neighborhood Hits	287	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

CN004_MOUSE
NC score	0.035037 (rank : 303)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	287	Target Neighborhood Hits	105	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

ZFYV1_HUMAN
NC score	0.034842 (rank : 304)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	287	Target Neighborhood Hits	166	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

RUFY1_HUMAN
NC score	0.034615 (rank : 305)	θ value	1.38821 (rank : 187)
Query Neighborhood Hits	287	Target Neighborhood Hits	848	Shared Neighborhood Hits	66
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

MYH11_HUMAN
NC score	0.033882 (rank : 306)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	287	Target Neighborhood Hits	1806	Shared Neighborhood Hits	97
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

FYCO1_HUMAN
NC score	0.033744 (rank : 307)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	287	Target Neighborhood Hits	1149	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

TFE2_MOUSE
NC score	0.033278 (rank : 308)	θ value	0.0736092 (rank : 126)
Query Neighborhood Hits	287	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

MYH9_HUMAN
NC score	0.032338 (rank : 309)	θ value	2.36792 (rank : 204)
Query Neighborhood Hits	287	Target Neighborhood Hits	1762	Shared Neighborhood Hits	93
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

FYCO1_MOUSE
NC score	0.032222 (rank : 310)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	287	Target Neighborhood Hits	1059	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

HOME1_HUMAN
NC score	0.031817 (rank : 311)	θ value	0.279714 (rank : 139)
Query Neighborhood Hits	287	Target Neighborhood Hits	564	Shared Neighborhood Hits	46
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

MYH9_MOUSE
NC score	0.031783 (rank : 312)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	287	Target Neighborhood Hits	1829	Shared Neighborhood Hits	95
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ZFYV1_MOUSE
NC score	0.031485 (rank : 313)	θ value	3.0926 (rank : 221)
Query Neighborhood Hits	287	Target Neighborhood Hits	153	Shared Neighborhood Hits	16
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

RNF31_HUMAN
NC score	0.031367 (rank : 314)	θ value	3.0926 (rank : 220)
Query Neighborhood Hits	287	Target Neighborhood Hits	110	Shared Neighborhood Hits	17
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

MYH10_MOUSE
NC score	0.031227 (rank : 315)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	287	Target Neighborhood Hits	1612	Shared Neighborhood Hits	89
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CROCC_HUMAN
NC score	0.031191 (rank : 316)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	287	Target Neighborhood Hits	1409	Shared Neighborhood Hits	79
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

TUFT1_MOUSE
NC score	0.030912 (rank : 317)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	287	Target Neighborhood Hits	732	Shared Neighborhood Hits	48
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

MYH10_HUMAN
NC score	0.030911 (rank : 318)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	287	Target Neighborhood Hits	1620	Shared Neighborhood Hits	92
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CA065_HUMAN
NC score	0.030868 (rank : 319)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	287	Target Neighborhood Hits	469	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

EP15_MOUSE
NC score	0.030513 (rank : 320)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	287	Target Neighborhood Hits	820	Shared Neighborhood Hits	55
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MYH11_MOUSE
NC score	0.030194 (rank : 321)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	287	Target Neighborhood Hits	1777	Shared Neighborhood Hits	92
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PCNT_MOUSE
NC score	0.030129 (rank : 322)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	287	Target Neighborhood Hits	1207	Shared Neighborhood Hits	76
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RAI14_HUMAN
NC score	0.028926 (rank : 323)	θ value	0.47712 (rank : 155)
Query Neighborhood Hits	287	Target Neighborhood Hits	1367	Shared Neighborhood Hits	71
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

I22RA_HUMAN
NC score	0.028680 (rank : 324)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	287	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q969J5, Q6UWM1, Q96A41, Q96QR0	Gene names	IL22RA2
Domain Architecture	No domain graphic available
Description	Interleukin-22 receptor alpha-2 chain precursor (IL-22R-alpha-2) (Interleukin 22-binding protein) (IL22BP) (Cytokine receptor family class II member 10) (CRF2-10) (Cytokine receptor family type 2, soluble 1) (CRF2-S1).

TITIN_HUMAN
NC score	0.028408 (rank : 325)	θ value	0.0193708 (rank : 115)
Query Neighborhood Hits	287	Target Neighborhood Hits	2923	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

BICD1_MOUSE
NC score	0.027375 (rank : 326)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	287	Target Neighborhood Hits	837	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

GOGA3_HUMAN
NC score	0.027260 (rank : 327)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	287	Target Neighborhood Hits	1317	Shared Neighborhood Hits	73
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

HOMEZ_HUMAN
NC score	0.025509 (rank : 328)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	287	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

SDK1_MOUSE
NC score	0.024687 (rank : 329)	θ value	1.81305 (rank : 198)
Query Neighborhood Hits	287	Target Neighborhood Hits	495	Shared Neighborhood Hits	35
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

GOGA2_HUMAN
NC score	0.023920 (rank : 330)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	287	Target Neighborhood Hits	856	Shared Neighborhood Hits	53
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

ZFN2B_MOUSE
NC score	0.023726 (rank : 331)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	287	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q91X58, Q9D0W4	Gene names	Zfand2b
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 2B.

NEO1_MOUSE
NC score	0.023405 (rank : 332)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	287	Target Neighborhood Hits	523	Shared Neighborhood Hits	40
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

LIPB1_MOUSE
NC score	0.023312 (rank : 333)	θ value	3.0926 (rank : 215)
Query Neighborhood Hits	287	Target Neighborhood Hits	727	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

RPGR1_HUMAN
NC score	0.023038 (rank : 334)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	287	Target Neighborhood Hits	578	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

NEO1_HUMAN
NC score	0.022455 (rank : 335)	θ value	2.36792 (rank : 207)
Query Neighborhood Hits	287	Target Neighborhood Hits	530	Shared Neighborhood Hits	40
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

CN045_HUMAN
NC score	0.022130 (rank : 336)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	287	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

ZFN2B_HUMAN
NC score	0.022091 (rank : 337)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	287	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WV99, Q8NB98	Gene names	ZFAND2B
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 2B.

CTGE6_HUMAN
NC score	0.022055 (rank : 338)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	287	Target Neighborhood Hits	650	Shared Neighborhood Hits	53
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

EVC_HUMAN
NC score	0.019411 (rank : 339)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	287	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

SDK2_HUMAN
NC score	0.018478 (rank : 340)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	287	Target Neighborhood Hits	495	Shared Neighborhood Hits	34
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

RTP3_MOUSE
NC score	0.017857 (rank : 341)	θ value	1.81305 (rank : 197)
Query Neighborhood Hits	287	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SDK1_HUMAN
NC score	0.017632 (rank : 342)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	287	Target Neighborhood Hits	511	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_MOUSE
NC score	0.015911 (rank : 343)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	287	Target Neighborhood Hits	480	Shared Neighborhood Hits	30
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

PEX26_HUMAN
NC score	0.015692 (rank : 344)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	287	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z412, Q7Z413, Q7Z414, Q7Z415, Q7Z416, Q96B12, Q9NWQ0, Q9NXU0	Gene names	PEX26
Domain Architecture
Description	Peroxisome assembly protein 26 (Peroxin-26).

EPHA7_HUMAN
NC score	0.015390 (rank : 345)	θ value	0.0193708 (rank : 113)
Query Neighborhood Hits	287	Target Neighborhood Hits	1053	Shared Neighborhood Hits	32
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
NC score	0.014896 (rank : 346)	θ value	0.0193708 (rank : 114)
Query Neighborhood Hits	287	Target Neighborhood Hits	1025	Shared Neighborhood Hits	32
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

K0226_HUMAN
NC score	0.014689 (rank : 347)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	287	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

ZFY27_HUMAN
NC score	0.014492 (rank : 348)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	287	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

EPHA5_HUMAN
NC score	0.013734 (rank : 349)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	287	Target Neighborhood Hits	1009	Shared Neighborhood Hits	32
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

MLL4_HUMAN
NC score	0.013400 (rank : 350)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	287	Target Neighborhood Hits	722	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

EPHA5_MOUSE
NC score	0.013396 (rank : 351)	θ value	3.0926 (rank : 212)
Query Neighborhood Hits	287	Target Neighborhood Hits	950	Shared Neighborhood Hits	32
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

CTRO_MOUSE
NC score	0.012796 (rank : 352)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	287	Target Neighborhood Hits	2344	Shared Neighborhood Hits	98
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

OBSL1_HUMAN
NC score	0.011740 (rank : 353)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	287	Target Neighborhood Hits	354	Shared Neighborhood Hits	19
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

EPHB2_HUMAN
NC score	0.010462 (rank : 354)	θ value	3.0926 (rank : 213)
Query Neighborhood Hits	287	Target Neighborhood Hits	983	Shared Neighborhood Hits	31
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
NC score	0.010446 (rank : 355)	θ value	3.0926 (rank : 214)
Query Neighborhood Hits	287	Target Neighborhood Hits	982	Shared Neighborhood Hits	31
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHA3_HUMAN
NC score	0.010378 (rank : 356)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	287	Target Neighborhood Hits	1005	Shared Neighborhood Hits	30
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

CTRO_HUMAN
NC score	0.010200 (rank : 357)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	287	Target Neighborhood Hits	2092	Shared Neighborhood Hits	81
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MUC5B_HUMAN
NC score	0.010193 (rank : 358)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	287	Target Neighborhood Hits	1020	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

K2C1B_HUMAN
NC score	0.008756 (rank : 359)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	287	Target Neighborhood Hits	542	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

EPHB4_MOUSE
NC score	0.008138 (rank : 360)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	287	Target Neighborhood Hits	1013	Shared Neighborhood Hits	28
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHA4_MOUSE
NC score	0.007776 (rank : 361)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	287	Target Neighborhood Hits	982	Shared Neighborhood Hits	29
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA4_HUMAN
NC score	0.007742 (rank : 362)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	287	Target Neighborhood Hits	975	Shared Neighborhood Hits	29
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHB4_HUMAN
NC score	0.007528 (rank : 363)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	287	Target Neighborhood Hits	1056	Shared Neighborhood Hits	29
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

K1C10_MOUSE
NC score	0.007136 (rank : 364)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	287	Target Neighborhood Hits	466	Shared Neighborhood Hits	37
SwissProt Accessions	P02535, P08731, Q8BUX3, Q8BV09, Q8BVU3, Q9CXH6, Q9JKB4	Gene names	Krt10, Krt1-10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) (56 kDa cytokeratin) (Keratin, type I cytoskeletal 59 kDa).

PRRT1_HUMAN
NC score	0.006892 (rank : 365)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	287	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

ICAM5_HUMAN
NC score	0.006781 (rank : 366)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	287	Target Neighborhood Hits	276	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

STX16_MOUSE
NC score	0.006152 (rank : 367)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	287	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVI5	Gene names	Stx16
Domain Architecture	No domain graphic available
Description	Syntaxin-16.

M4K4_HUMAN
NC score	0.004542 (rank : 368)	θ value	2.36792 (rank : 203)
Query Neighborhood Hits	287	Target Neighborhood Hits	1589	Shared Neighborhood Hits	62
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

DJC16_MOUSE
NC score	0.004185 (rank : 369)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	287	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TN4, Q811G1, Q8BHI2	Gene names	Dnajc16, Kiaa0962
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 16 precursor.

ABCAD_HUMAN
NC score	0.003063 (rank : 370)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	287	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ZN687_MOUSE
NC score	-0.001038 (rank : 371)	θ value	3.0926 (rank : 222)
Query Neighborhood Hits	287	Target Neighborhood Hits	913	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ZN408_HUMAN
NC score	-0.004140 (rank : 372)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	287	Target Neighborhood Hits	775	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

ZN283_HUMAN
NC score	-0.004418 (rank : 373)	θ value	0.62314 (rank : 160)
Query Neighborhood Hits	287	Target Neighborhood Hits	760	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N7M2	Gene names	ZNF283
Domain Architecture	No domain graphic available
Description	Zinc finger protein 283.

ZN567_HUMAN
NC score	-0.005754 (rank : 374)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	287	Target Neighborhood Hits	769	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N184, Q6N044	Gene names	ZNF567
Domain Architecture	No domain graphic available
Description	Zinc finger protein 567.

ZNF12_HUMAN
NC score	-0.006120 (rank : 375)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	287	Target Neighborhood Hits	779	Shared Neighborhood Hits	14
SwissProt Accessions	P17014, Q9ULZ6	Gene names	ZNF12, GIOT3, KOX3, ZNF325
Domain Architecture	No domain graphic available
Description	Zinc finger protein 12 (Zinc finger protein KOX3) (Zinc finger protein 325) (Gonadotropin-inducible transcription repressor 3) (GIOT-3).

ZN436_HUMAN
NC score	-0.006553 (rank : 376)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	287	Target Neighborhood Hits	756	Shared Neighborhood Hits	11
SwissProt Accessions	Q9C0F3, Q658I9	Gene names	ZNF436, KIAA1710
Domain Architecture
Description	Zinc finger protein 436.