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Network neighborhood for query Sequence : TRIM1_HUMAN

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TRIM1_HUMAN
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRI18_HUMAN
θ value	0 (rank : 1)	NC score	0.978702 (rank : 4)
Query Neighborhood Hits	345	Target Neighborhood Hits	307	Shared Neighborhood Hits	242
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	0 (rank : 2)	NC score	0.981161 (rank : 3)
Query Neighborhood Hits	345	Target Neighborhood Hits	292	Shared Neighborhood Hits	238
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRIM1_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	345	Target Neighborhood Hits	345	Shared Neighborhood Hits	345
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0 (rank : 4)	NC score	0.997071 (rank : 2)
Query Neighborhood Hits	345	Target Neighborhood Hits	361	Shared Neighborhood Hits	336
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI36_MOUSE
θ value	2.32979e-56 (rank : 5)	NC score	0.859031 (rank : 5)
Query Neighborhood Hits	345	Target Neighborhood Hits	266	Shared Neighborhood Hits	191
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI36_HUMAN
θ value	3.0428e-56 (rank : 6)	NC score	0.857573 (rank : 6)
Query Neighborhood Hits	345	Target Neighborhood Hits	282	Shared Neighborhood Hits	191
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI46_HUMAN
θ value	9.48078e-50 (rank : 7)	NC score	0.853192 (rank : 8)
Query Neighborhood Hits	345	Target Neighborhood Hits	291	Shared Neighborhood Hits	200
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	1.36902e-48 (rank : 8)	NC score	0.853788 (rank : 7)
Query Neighborhood Hits	345	Target Neighborhood Hits	287	Shared Neighborhood Hits	200
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM9_HUMAN
θ value	4.40402e-47 (rank : 9)	NC score	0.819950 (rank : 9)
Query Neighborhood Hits	345	Target Neighborhood Hits	294	Shared Neighborhood Hits	189
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	7.52953e-39 (rank : 10)	NC score	0.795456 (rank : 10)
Query Neighborhood Hits	345	Target Neighborhood Hits	274	Shared Neighborhood Hits	184
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI25_HUMAN
θ value	6.17384e-33 (rank : 11)	NC score	0.778141 (rank : 16)
Query Neighborhood Hits	345	Target Neighborhood Hits	472	Shared Neighborhood Hits	249
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI55_HUMAN
θ value	5.77852e-31 (rank : 12)	NC score	0.782755 (rank : 13)
Query Neighborhood Hits	345	Target Neighborhood Hits	292	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI63_MOUSE
θ value	2.96777e-27 (rank : 13)	NC score	0.792166 (rank : 11)
Query Neighborhood Hits	345	Target Neighborhood Hits	240	Shared Neighborhood Hits	183
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI54_MOUSE
θ value	2.51237e-26 (rank : 14)	NC score	0.783268 (rank : 12)
Query Neighborhood Hits	345	Target Neighborhood Hits	197	Shared Neighborhood Hits	164
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI42_MOUSE
θ value	6.18819e-25 (rank : 15)	NC score	0.694803 (rank : 25)
Query Neighborhood Hits	345	Target Neighborhood Hits	316	Shared Neighborhood Hits	139
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI63_HUMAN
θ value	6.18819e-25 (rank : 16)	NC score	0.780888 (rank : 14)
Query Neighborhood Hits	345	Target Neighborhood Hits	298	Shared Neighborhood Hits	191
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI54_HUMAN
θ value	8.08199e-25 (rank : 17)	NC score	0.779409 (rank : 15)
Query Neighborhood Hits	345	Target Neighborhood Hits	209	Shared Neighborhood Hits	168
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM8_MOUSE
θ value	1.99067e-23 (rank : 18)	NC score	0.744722 (rank : 18)
Query Neighborhood Hits	345	Target Neighborhood Hits	674	Shared Neighborhood Hits	238
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
θ value	9.87957e-23 (rank : 19)	NC score	0.741836 (rank : 19)
Query Neighborhood Hits	345	Target Neighborhood Hits	650	Shared Neighborhood Hits	239
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI42_HUMAN
θ value	3.75424e-22 (rank : 20)	NC score	0.688429 (rank : 27)
Query Neighborhood Hits	345	Target Neighborhood Hits	283	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI25_MOUSE
θ value	1.13037e-18 (rank : 21)	NC score	0.755098 (rank : 17)
Query Neighborhood Hits	345	Target Neighborhood Hits	446	Shared Neighborhood Hits	238
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI45_MOUSE
θ value	1.24977e-17 (rank : 22)	NC score	0.634270 (rank : 44)
Query Neighborhood Hits	345	Target Neighborhood Hits	155	Shared Neighborhood Hits	115
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

ARD1_HUMAN
θ value	1.63225e-17 (rank : 23)	NC score	0.308182 (rank : 155)
Query Neighborhood Hits	345	Target Neighborhood Hits	621	Shared Neighborhood Hits	91
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	6.20254e-17 (rank : 24)	NC score	0.316895 (rank : 153)
Query Neighborhood Hits	345	Target Neighborhood Hits	573	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

TRI45_HUMAN
θ value	4.02038e-16 (rank : 25)	NC score	0.631649 (rank : 49)
Query Neighborhood Hits	345	Target Neighborhood Hits	155	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TIF1G_HUMAN
θ value	1.52774e-15 (rank : 26)	NC score	0.506574 (rank : 105)
Query Neighborhood Hits	345	Target Neighborhood Hits	410	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	1.52774e-15 (rank : 27)	NC score	0.500507 (rank : 106)
Query Neighborhood Hits	345	Target Neighborhood Hits	498	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI59_HUMAN
θ value	1.99529e-15 (rank : 28)	NC score	0.721665 (rank : 21)
Query Neighborhood Hits	345	Target Neighborhood Hits	307	Shared Neighborhood Hits	203
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	3.40345e-15 (rank : 29)	NC score	0.722742 (rank : 20)
Query Neighborhood Hits	345	Target Neighborhood Hits	292	Shared Neighborhood Hits	201
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

SPRY4_HUMAN
θ value	2.20605e-14 (rank : 30)	NC score	0.609759 (rank : 79)
Query Neighborhood Hits	345	Target Neighborhood Hits	79	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI13_HUMAN
θ value	2.20605e-14 (rank : 31)	NC score	0.696050 (rank : 23)
Query Neighborhood Hits	345	Target Neighborhood Hits	274	Shared Neighborhood Hits	196
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

BT3A1_HUMAN
θ value	3.76295e-14 (rank : 32)	NC score	0.481611 (rank : 112)
Query Neighborhood Hits	345	Target Neighborhood Hits	229	Shared Neighborhood Hits	88
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

SPRY4_MOUSE
θ value	3.76295e-14 (rank : 33)	NC score	0.621460 (rank : 61)
Query Neighborhood Hits	345	Target Neighborhood Hits	82	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TIF1A_HUMAN
θ value	6.41864e-14 (rank : 34)	NC score	0.429893 (rank : 127)
Query Neighborhood Hits	345	Target Neighborhood Hits	327	Shared Neighborhood Hits	110
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRI13_MOUSE
θ value	8.38298e-14 (rank : 35)	NC score	0.695171 (rank : 24)
Query Neighborhood Hits	345	Target Neighborhood Hits	282	Shared Neighborhood Hits	195
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TIF1B_HUMAN
θ value	1.09485e-13 (rank : 36)	NC score	0.515802 (rank : 98)
Query Neighborhood Hits	345	Target Neighborhood Hits	312	Shared Neighborhood Hits	115
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	1.42992e-13 (rank : 37)	NC score	0.511477 (rank : 100)
Query Neighborhood Hits	345	Target Neighborhood Hits	276	Shared Neighborhood Hits	110
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI47_MOUSE
θ value	1.42992e-13 (rank : 38)	NC score	0.703635 (rank : 22)
Query Neighborhood Hits	345	Target Neighborhood Hits	295	Shared Neighborhood Hits	205
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TIF1A_MOUSE
θ value	2.43908e-13 (rank : 39)	NC score	0.399483 (rank : 130)
Query Neighborhood Hits	345	Target Neighborhood Hits	307	Shared Neighborhood Hits	100
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI16_MOUSE
θ value	7.09661e-13 (rank : 40)	NC score	0.643081 (rank : 37)
Query Neighborhood Hits	345	Target Neighborhood Hits	196	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI14_MOUSE
θ value	9.26847e-13 (rank : 41)	NC score	0.682318 (rank : 28)
Query Neighborhood Hits	345	Target Neighborhood Hits	137	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI47_HUMAN
θ value	1.58096e-12 (rank : 42)	NC score	0.691072 (rank : 26)
Query Neighborhood Hits	345	Target Neighborhood Hits	286	Shared Neighborhood Hits	207
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

ERMAP_MOUSE
θ value	2.0648e-12 (rank : 43)	NC score	0.491732 (rank : 108)
Query Neighborhood Hits	345	Target Neighborhood Hits	231	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

TRI14_HUMAN
θ value	2.69671e-12 (rank : 44)	NC score	0.676557 (rank : 29)
Query Neighborhood Hits	345	Target Neighborhood Hits	143	Shared Neighborhood Hits	121
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI29_HUMAN
θ value	2.69671e-12 (rank : 45)	NC score	0.591658 (rank : 85)
Query Neighborhood Hits	345	Target Neighborhood Hits	273	Shared Neighborhood Hits	120
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

BT1A1_MOUSE
θ value	3.52202e-12 (rank : 46)	NC score	0.486968 (rank : 110)
Query Neighborhood Hits	345	Target Neighborhood Hits	252	Shared Neighborhood Hits	87
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

ERMAP_HUMAN
θ value	3.52202e-12 (rank : 47)	NC score	0.511316 (rank : 101)
Query Neighborhood Hits	345	Target Neighborhood Hits	155	Shared Neighborhood Hits	81
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

BT1A1_HUMAN
θ value	4.59992e-12 (rank : 48)	NC score	0.483608 (rank : 111)
Query Neighborhood Hits	345	Target Neighborhood Hits	322	Shared Neighborhood Hits	90
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A3_HUMAN
θ value	6.00763e-12 (rank : 49)	NC score	0.480050 (rank : 114)
Query Neighborhood Hits	345	Target Neighborhood Hits	233	Shared Neighborhood Hits	85
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

TRIM3_MOUSE
θ value	6.00763e-12 (rank : 50)	NC score	0.647774 (rank : 35)
Query Neighborhood Hits	345	Target Neighborhood Hits	351	Shared Neighborhood Hits	193
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI16_HUMAN
θ value	1.74796e-11 (rank : 51)	NC score	0.625372 (rank : 56)
Query Neighborhood Hits	345	Target Neighborhood Hits	231	Shared Neighborhood Hits	137
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI39_MOUSE
θ value	1.74796e-11 (rank : 52)	NC score	0.641380 (rank : 39)
Query Neighborhood Hits	345	Target Neighborhood Hits	691	Shared Neighborhood Hits	275
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI41_HUMAN
θ value	1.74796e-11 (rank : 53)	NC score	0.638437 (rank : 42)
Query Neighborhood Hits	345	Target Neighborhood Hits	349	Shared Neighborhood Hits	209
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI56_MOUSE
θ value	2.28291e-11 (rank : 54)	NC score	0.660013 (rank : 32)
Query Neighborhood Hits	345	Target Neighborhood Hits	255	Shared Neighborhood Hits	174
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

BSPRY_MOUSE
θ value	2.98157e-11 (rank : 55)	NC score	0.563572 (rank : 93)
Query Neighborhood Hits	345	Target Neighborhood Hits	163	Shared Neighborhood Hits	99
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI29_MOUSE
θ value	2.98157e-11 (rank : 56)	NC score	0.595815 (rank : 83)
Query Neighborhood Hits	345	Target Neighborhood Hits	306	Shared Neighborhood Hits	130
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI39_HUMAN
θ value	2.98157e-11 (rank : 57)	NC score	0.641914 (rank : 38)
Query Neighborhood Hits	345	Target Neighborhood Hits	693	Shared Neighborhood Hits	268
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

BTNL9_HUMAN
θ value	3.89403e-11 (rank : 58)	NC score	0.474366 (rank : 115)
Query Neighborhood Hits	345	Target Neighborhood Hits	125	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

TRI68_HUMAN
θ value	5.08577e-11 (rank : 59)	NC score	0.615844 (rank : 70)
Query Neighborhood Hits	345	Target Neighborhood Hits	267	Shared Neighborhood Hits	203
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRIM3_HUMAN
θ value	5.08577e-11 (rank : 60)	NC score	0.639600 (rank : 40)
Query Neighborhood Hits	345	Target Neighborhood Hits	357	Shared Neighborhood Hits	197
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM2_HUMAN
θ value	6.64225e-11 (rank : 61)	NC score	0.636649 (rank : 43)
Query Neighborhood Hits	345	Target Neighborhood Hits	330	Shared Neighborhood Hits	195
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

BSPRY_HUMAN
θ value	8.67504e-11 (rank : 62)	NC score	0.571053 (rank : 89)
Query Neighborhood Hits	345	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRIM2_MOUSE
θ value	8.67504e-11 (rank : 63)	NC score	0.634074 (rank : 45)
Query Neighborhood Hits	345	Target Neighborhood Hits	331	Shared Neighborhood Hits	196
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI26_HUMAN
θ value	1.133e-10 (rank : 64)	NC score	0.610755 (rank : 77)
Query Neighborhood Hits	345	Target Neighborhood Hits	335	Shared Neighborhood Hits	217
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI11_MOUSE
θ value	2.52405e-10 (rank : 65)	NC score	0.627105 (rank : 55)
Query Neighborhood Hits	345	Target Neighborhood Hits	329	Shared Neighborhood Hits	217
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI34_HUMAN
θ value	2.52405e-10 (rank : 66)	NC score	0.622038 (rank : 60)
Query Neighborhood Hits	345	Target Neighborhood Hits	416	Shared Neighborhood Hits	227
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI56_HUMAN
θ value	3.29651e-10 (rank : 67)	NC score	0.643389 (rank : 36)
Query Neighborhood Hits	345	Target Neighborhood Hits	339	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI32_MOUSE
θ value	7.34386e-10 (rank : 68)	NC score	0.567506 (rank : 91)
Query Neighborhood Hits	345	Target Neighborhood Hits	271	Shared Neighborhood Hits	176
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI68_MOUSE
θ value	7.34386e-10 (rank : 69)	NC score	0.624238 (rank : 57)
Query Neighborhood Hits	345	Target Neighborhood Hits	356	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI32_HUMAN
θ value	1.63604e-09 (rank : 70)	NC score	0.567030 (rank : 92)
Query Neighborhood Hits	345	Target Neighborhood Hits	264	Shared Neighborhood Hits	170
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI50_HUMAN
θ value	2.13673e-09 (rank : 71)	NC score	0.669653 (rank : 30)
Query Neighborhood Hits	345	Target Neighborhood Hits	294	Shared Neighborhood Hits	218
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI11_HUMAN
θ value	3.64472e-09 (rank : 72)	NC score	0.627275 (rank : 54)
Query Neighborhood Hits	345	Target Neighborhood Hits	316	Shared Neighborhood Hits	216
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI62_MOUSE
θ value	3.64472e-09 (rank : 73)	NC score	0.659459 (rank : 33)
Query Neighborhood Hits	345	Target Neighborhood Hits	478	Shared Neighborhood Hits	241
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM4_HUMAN
θ value	4.76016e-09 (rank : 74)	NC score	0.633343 (rank : 46)
Query Neighborhood Hits	345	Target Neighborhood Hits	321	Shared Neighborhood Hits	225
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI50_MOUSE
θ value	6.21693e-09 (rank : 75)	NC score	0.669478 (rank : 31)
Query Neighborhood Hits	345	Target Neighborhood Hits	326	Shared Neighborhood Hits	226
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI22_HUMAN
θ value	1.06045e-08 (rank : 76)	NC score	0.618689 (rank : 63)
Query Neighborhood Hits	345	Target Neighborhood Hits	396	Shared Neighborhood Hits	230
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI62_HUMAN
θ value	1.06045e-08 (rank : 77)	NC score	0.656729 (rank : 34)
Query Neighborhood Hits	345	Target Neighborhood Hits	584	Shared Neighborhood Hits	251
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI60_MOUSE
θ value	1.38499e-08 (rank : 78)	NC score	0.615981 (rank : 69)
Query Neighborhood Hits	345	Target Neighborhood Hits	240	Shared Neighborhood Hits	188
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRIM6_HUMAN
θ value	1.38499e-08 (rank : 79)	NC score	0.606100 (rank : 80)
Query Neighborhood Hits	345	Target Neighborhood Hits	412	Shared Neighborhood Hits	234
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI35_MOUSE
θ value	1.80886e-08 (rank : 80)	NC score	0.623781 (rank : 58)
Query Neighborhood Hits	345	Target Neighborhood Hits	465	Shared Neighborhood Hits	247
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI31_HUMAN
θ value	4.0297e-08 (rank : 81)	NC score	0.622980 (rank : 59)
Query Neighborhood Hits	345	Target Neighborhood Hits	299	Shared Neighborhood Hits	208
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI26_MOUSE
θ value	5.26297e-08 (rank : 82)	NC score	0.598512 (rank : 82)
Query Neighborhood Hits	345	Target Neighborhood Hits	339	Shared Neighborhood Hits	217
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI27_HUMAN
θ value	5.26297e-08 (rank : 83)	NC score	0.629572 (rank : 52)
Query Neighborhood Hits	345	Target Neighborhood Hits	273	Shared Neighborhood Hits	209
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	5.26297e-08 (rank : 84)	NC score	0.627498 (rank : 53)
Query Neighborhood Hits	345	Target Neighborhood Hits	261	Shared Neighborhood Hits	200
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

BT2A2_HUMAN
θ value	8.97725e-08 (rank : 85)	NC score	0.471982 (rank : 116)
Query Neighborhood Hits	345	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRI38_HUMAN
θ value	8.97725e-08 (rank : 86)	NC score	0.613984 (rank : 72)
Query Neighborhood Hits	345	Target Neighborhood Hits	373	Shared Neighborhood Hits	223
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI12_MOUSE
θ value	1.53129e-07 (rank : 87)	NC score	0.588429 (rank : 86)
Query Neighborhood Hits	345	Target Neighborhood Hits	387	Shared Neighborhood Hits	208
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM7_MOUSE
θ value	1.53129e-07 (rank : 88)	NC score	0.631845 (rank : 48)
Query Neighborhood Hits	345	Target Neighborhood Hits	358	Shared Neighborhood Hits	224
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI60_HUMAN
θ value	2.61198e-07 (rank : 89)	NC score	0.631852 (rank : 47)
Query Neighborhood Hits	345	Target Neighborhood Hits	357	Shared Neighborhood Hits	237
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRIM5_HUMAN
θ value	4.45536e-07 (rank : 90)	NC score	0.611230 (rank : 75)
Query Neighborhood Hits	345	Target Neighborhood Hits	424	Shared Neighborhood Hits	240
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI35_HUMAN
θ value	5.81887e-07 (rank : 91)	NC score	0.616434 (rank : 68)
Query Neighborhood Hits	345	Target Neighborhood Hits	382	Shared Neighborhood Hits	225
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI15_HUMAN
θ value	9.92553e-07 (rank : 92)	NC score	0.618405 (rank : 64)
Query Neighborhood Hits	345	Target Neighborhood Hits	395	Shared Neighborhood Hits	230
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

RO52_HUMAN
θ value	1.29631e-06 (rank : 93)	NC score	0.613520 (rank : 74)
Query Neighborhood Hits	345	Target Neighborhood Hits	419	Shared Neighborhood Hits	246
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI30_MOUSE
θ value	1.29631e-06 (rank : 94)	NC score	0.610600 (rank : 78)
Query Neighborhood Hits	345	Target Neighborhood Hits	434	Shared Neighborhood Hits	240
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI34_MOUSE
θ value	1.29631e-06 (rank : 95)	NC score	0.582600 (rank : 87)
Query Neighborhood Hits	345	Target Neighborhood Hits	332	Shared Neighborhood Hits	201
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI44_MOUSE
θ value	1.29631e-06 (rank : 96)	NC score	0.516396 (rank : 97)
Query Neighborhood Hits	345	Target Neighborhood Hits	327	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI73_HUMAN
θ value	1.29631e-06 (rank : 97)	NC score	0.630751 (rank : 50)
Query Neighborhood Hits	345	Target Neighborhood Hits	258	Shared Neighborhood Hits	204
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	1.29631e-06 (rank : 98)	NC score	0.629694 (rank : 51)
Query Neighborhood Hits	345	Target Neighborhood Hits	249	Shared Neighborhood Hits	198
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI65_HUMAN
θ value	1.69304e-06 (rank : 99)	NC score	0.638770 (rank : 41)
Query Neighborhood Hits	345	Target Neighborhood Hits	330	Shared Neighborhood Hits	224
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM7_HUMAN
θ value	1.69304e-06 (rank : 100)	NC score	0.616666 (rank : 67)
Query Neighborhood Hits	345	Target Neighborhood Hits	336	Shared Neighborhood Hits	222
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

PML_MOUSE
θ value	2.21117e-06 (rank : 101)	NC score	0.439278 (rank : 123)
Query Neighborhood Hits	345	Target Neighborhood Hits	246	Shared Neighborhood Hits	134
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRIM6_MOUSE
θ value	2.21117e-06 (rank : 102)	NC score	0.599510 (rank : 81)
Query Neighborhood Hits	345	Target Neighborhood Hits	451	Shared Neighborhood Hits	238
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

BTNL3_HUMAN
θ value	2.88788e-06 (rank : 103)	NC score	0.464378 (rank : 117)
Query Neighborhood Hits	345	Target Neighborhood Hits	143	Shared Neighborhood Hits	80
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRI43_HUMAN
θ value	2.88788e-06 (rank : 104)	NC score	0.582391 (rank : 88)
Query Neighborhood Hits	345	Target Neighborhood Hits	341	Shared Neighborhood Hits	220
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI17_MOUSE
θ value	3.77169e-06 (rank : 105)	NC score	0.620653 (rank : 62)
Query Neighborhood Hits	345	Target Neighborhood Hits	620	Shared Neighborhood Hits	254
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI44_HUMAN
θ value	3.77169e-06 (rank : 106)	NC score	0.509407 (rank : 102)
Query Neighborhood Hits	345	Target Neighborhood Hits	393	Shared Neighborhood Hits	116
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

BT2A3_HUMAN
θ value	4.92598e-06 (rank : 107)	NC score	0.448612 (rank : 120)
Query Neighborhood Hits	345	Target Neighborhood Hits	195	Shared Neighborhood Hits	78
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

RO52_MOUSE
θ value	4.92598e-06 (rank : 108)	NC score	0.592559 (rank : 84)
Query Neighborhood Hits	345	Target Neighborhood Hits	360	Shared Neighborhood Hits	227
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI17_HUMAN
θ value	4.92598e-06 (rank : 109)	NC score	0.617388 (rank : 65)
Query Neighborhood Hits	345	Target Neighborhood Hits	318	Shared Neighborhood Hits	213
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

MEFV_HUMAN
θ value	6.43352e-06 (rank : 110)	NC score	0.544410 (rank : 95)
Query Neighborhood Hits	345	Target Neighborhood Hits	431	Shared Neighborhood Hits	150
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

RNF39_HUMAN
θ value	1.43324e-05 (rank : 111)	NC score	0.610926 (rank : 76)
Query Neighborhood Hits	345	Target Neighborhood Hits	200	Shared Neighborhood Hits	175
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI10_MOUSE
θ value	1.87187e-05 (rank : 112)	NC score	0.616818 (rank : 66)
Query Neighborhood Hits	345	Target Neighborhood Hits	285	Shared Neighborhood Hits	214
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

RFPL1_HUMAN
θ value	2.44474e-05 (rank : 113)	NC score	0.488410 (rank : 109)
Query Neighborhood Hits	345	Target Neighborhood Hits	119	Shared Neighborhood Hits	111
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFWD2_HUMAN
θ value	4.1701e-05 (rank : 114)	NC score	0.272964 (rank : 161)
Query Neighborhood Hits	345	Target Neighborhood Hits	518	Shared Neighborhood Hits	171
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	4.1701e-05 (rank : 115)	NC score	0.273129 (rank : 160)
Query Neighborhood Hits	345	Target Neighborhood Hits	535	Shared Neighborhood Hits	175
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFPL3_HUMAN
θ value	7.1131e-05 (rank : 116)	NC score	0.495053 (rank : 107)
Query Neighborhood Hits	345	Target Neighborhood Hits	134	Shared Neighborhood Hits	122
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

TRI65_MOUSE
θ value	0.000121331 (rank : 117)	NC score	0.615010 (rank : 71)
Query Neighborhood Hits	345	Target Neighborhood Hits	340	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RFPL2_HUMAN
θ value	0.000158464 (rank : 118)	NC score	0.481094 (rank : 113)
Query Neighborhood Hits	345	Target Neighborhood Hits	126	Shared Neighborhood Hits	114
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRI48_HUMAN
θ value	0.000158464 (rank : 119)	NC score	0.558524 (rank : 94)
Query Neighborhood Hits	345	Target Neighborhood Hits	192	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

BT2A1_HUMAN
θ value	0.00020696 (rank : 120)	NC score	0.449900 (rank : 119)
Query Neighborhood Hits	345	Target Neighborhood Hits	185	Shared Neighborhood Hits	85
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

ZN313_MOUSE
θ value	0.00020696 (rank : 121)	NC score	0.462434 (rank : 118)
Query Neighborhood Hits	345	Target Neighborhood Hits	273	Shared Neighborhood Hits	175
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRI37_HUMAN
θ value	0.000461057 (rank : 122)	NC score	0.508877 (rank : 103)
Query Neighborhood Hits	345	Target Neighborhood Hits	307	Shared Neighborhood Hits	173
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	0.000461057 (rank : 123)	NC score	0.508425 (rank : 104)
Query Neighborhood Hits	345	Target Neighborhood Hits	316	Shared Neighborhood Hits	171
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI52_HUMAN
θ value	0.000461057 (rank : 124)	NC score	0.569093 (rank : 90)
Query Neighborhood Hits	345	Target Neighborhood Hits	213	Shared Neighborhood Hits	173
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

RAD18_HUMAN
θ value	0.000602161 (rank : 125)	NC score	0.334540 (rank : 147)
Query Neighborhood Hits	345	Target Neighborhood Hits	284	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

TRI10_HUMAN
θ value	0.000602161 (rank : 126)	NC score	0.613683 (rank : 73)
Query Neighborhood Hits	345	Target Neighborhood Hits	315	Shared Neighborhood Hits	222
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI49_HUMAN
θ value	0.000602161 (rank : 127)	NC score	0.540626 (rank : 96)
Query Neighborhood Hits	345	Target Neighborhood Hits	199	Shared Neighborhood Hits	177
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

UHRF2_MOUSE
θ value	0.000786445 (rank : 128)	NC score	0.301207 (rank : 156)
Query Neighborhood Hits	345	Target Neighborhood Hits	275	Shared Neighborhood Hits	151
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZN313_HUMAN
θ value	0.00134147 (rank : 129)	NC score	0.446421 (rank : 121)
Query Neighborhood Hits	345	Target Neighborhood Hits	264	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

BTNL8_HUMAN
θ value	0.00175202 (rank : 130)	NC score	0.436094 (rank : 124)
Query Neighborhood Hits	345	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

ROBO2_HUMAN
θ value	0.00175202 (rank : 131)	NC score	0.041288 (rank : 469)
Query Neighborhood Hits	345	Target Neighborhood Hits	479	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_MOUSE
θ value	0.00175202 (rank : 132)	NC score	0.041699 (rank : 467)
Query Neighborhood Hits	345	Target Neighborhood Hits	504	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

BRCA1_MOUSE
θ value	0.00228821 (rank : 133)	NC score	0.398421 (rank : 131)
Query Neighborhood Hits	345	Target Neighborhood Hits	436	Shared Neighborhood Hits	177
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

IFT74_HUMAN
θ value	0.00298849 (rank : 134)	NC score	0.077820 (rank : 258)
Query Neighborhood Hits	345	Target Neighborhood Hits	949	Shared Neighborhood Hits	104
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

RAD18_MOUSE
θ value	0.00298849 (rank : 135)	NC score	0.348510 (rank : 140)
Query Neighborhood Hits	345	Target Neighborhood Hits	230	Shared Neighborhood Hits	124
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

ZN179_HUMAN
θ value	0.00298849 (rank : 136)	NC score	0.432614 (rank : 126)
Query Neighborhood Hits	345	Target Neighborhood Hits	178	Shared Neighborhood Hits	135
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

MYH9_HUMAN
θ value	0.00390308 (rank : 137)	NC score	0.066702 (rank : 287)
Query Neighborhood Hits	345	Target Neighborhood Hits	1762	Shared Neighborhood Hits	146
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

UHRF2_HUMAN
θ value	0.00390308 (rank : 138)	NC score	0.298045 (rank : 158)
Query Neighborhood Hits	345	Target Neighborhood Hits	269	Shared Neighborhood Hits	152
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

MYH9_MOUSE
θ value	0.00509761 (rank : 139)	NC score	0.066652 (rank : 288)
Query Neighborhood Hits	345	Target Neighborhood Hits	1829	Shared Neighborhood Hits	148
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RING1_HUMAN
θ value	0.00509761 (rank : 140)	NC score	0.359500 (rank : 137)
Query Neighborhood Hits	345	Target Neighborhood Hits	219	Shared Neighborhood Hits	145
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.00509761 (rank : 141)	NC score	0.354011 (rank : 138)
Query Neighborhood Hits	345	Target Neighborhood Hits	220	Shared Neighborhood Hits	145
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

LNX1_MOUSE
θ value	0.00665767 (rank : 142)	NC score	0.216800 (rank : 185)
Query Neighborhood Hits	345	Target Neighborhood Hits	377	Shared Neighborhood Hits	146
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RING2_HUMAN
θ value	0.00665767 (rank : 143)	NC score	0.337648 (rank : 146)
Query Neighborhood Hits	345	Target Neighborhood Hits	201	Shared Neighborhood Hits	140
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.00665767 (rank : 144)	NC score	0.337760 (rank : 145)
Query Neighborhood Hits	345	Target Neighborhood Hits	199	Shared Neighborhood Hits	140
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

BRCA1_HUMAN
θ value	0.00869519 (rank : 145)	NC score	0.402400 (rank : 129)
Query Neighborhood Hits	345	Target Neighborhood Hits	381	Shared Neighborhood Hits	180
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

LNX1_HUMAN
θ value	0.00869519 (rank : 146)	NC score	0.215775 (rank : 187)
Query Neighborhood Hits	345	Target Neighborhood Hits	379	Shared Neighborhood Hits	153
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

RN168_HUMAN
θ value	0.00869519 (rank : 147)	NC score	0.434453 (rank : 125)
Query Neighborhood Hits	345	Target Neighborhood Hits	370	Shared Neighborhood Hits	179
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

MYH7_HUMAN
θ value	0.0113563 (rank : 148)	NC score	0.060030 (rank : 322)
Query Neighborhood Hits	345	Target Neighborhood Hits	1559	Shared Neighborhood Hits	123
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

RNF8_HUMAN
θ value	0.0113563 (rank : 149)	NC score	0.368036 (rank : 136)
Query Neighborhood Hits	345	Target Neighborhood Hits	622	Shared Neighborhood Hits	235
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

MEFV_MOUSE
θ value	0.0148317 (rank : 150)	NC score	0.443170 (rank : 122)
Query Neighborhood Hits	345	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

RNF8_MOUSE
θ value	0.0148317 (rank : 151)	NC score	0.374833 (rank : 135)
Query Neighborhood Hits	345	Target Neighborhood Hits	618	Shared Neighborhood Hits	235
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

EEA1_HUMAN
θ value	0.0193708 (rank : 152)	NC score	0.073342 (rank : 272)
Query Neighborhood Hits	345	Target Neighborhood Hits	1796	Shared Neighborhood Hits	153
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RN166_HUMAN
θ value	0.0193708 (rank : 153)	NC score	0.392841 (rank : 132)
Query Neighborhood Hits	345	Target Neighborhood Hits	240	Shared Neighborhood Hits	156
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

NIN_HUMAN
θ value	0.0330416 (rank : 154)	NC score	0.073281 (rank : 273)
Query Neighborhood Hits	345	Target Neighborhood Hits	1416	Shared Neighborhood Hits	126
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PLVAP_HUMAN
θ value	0.0330416 (rank : 155)	NC score	0.083408 (rank : 251)
Query Neighborhood Hits	345	Target Neighborhood Hits	397	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

TRAF6_MOUSE
θ value	0.0330416 (rank : 156)	NC score	0.270475 (rank : 163)
Query Neighborhood Hits	345	Target Neighborhood Hits	255	Shared Neighborhood Hits	167
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

MYOM1_HUMAN
θ value	0.0431538 (rank : 157)	NC score	0.054689 (rank : 389)
Query Neighborhood Hits	345	Target Neighborhood Hits	405	Shared Neighborhood Hits	28
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

PZRN4_HUMAN
θ value	0.0431538 (rank : 158)	NC score	0.183711 (rank : 198)
Query Neighborhood Hits	345	Target Neighborhood Hits	438	Shared Neighborhood Hits	169
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RN166_MOUSE
θ value	0.0431538 (rank : 159)	NC score	0.388217 (rank : 134)
Query Neighborhood Hits	345	Target Neighborhood Hits	248	Shared Neighborhood Hits	163
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TITIN_HUMAN
θ value	0.0431538 (rank : 160)	NC score	0.027245 (rank : 488)
Query Neighborhood Hits	345	Target Neighborhood Hits	2923	Shared Neighborhood Hits	111
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CHFR_MOUSE
θ value	0.0563607 (rank : 161)	NC score	0.321553 (rank : 149)
Query Neighborhood Hits	345	Target Neighborhood Hits	264	Shared Neighborhood Hits	152
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

EEA1_MOUSE
θ value	0.0563607 (rank : 162)	NC score	0.068703 (rank : 281)
Query Neighborhood Hits	345	Target Neighborhood Hits	1637	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GOGA4_HUMAN
θ value	0.0563607 (rank : 163)	NC score	0.074861 (rank : 266)
Query Neighborhood Hits	345	Target Neighborhood Hits	2034	Shared Neighborhood Hits	159
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGB1_HUMAN
θ value	0.0563607 (rank : 164)	NC score	0.082384 (rank : 252)
Query Neighborhood Hits	345	Target Neighborhood Hits	2297	Shared Neighborhood Hits	174
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LNX2_HUMAN
θ value	0.0563607 (rank : 165)	NC score	0.222117 (rank : 182)
Query Neighborhood Hits	345	Target Neighborhood Hits	389	Shared Neighborhood Hits	155
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RN168_MOUSE
θ value	0.0563607 (rank : 166)	NC score	0.419078 (rank : 128)
Query Neighborhood Hits	345	Target Neighborhood Hits	440	Shared Neighborhood Hits	191
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TXLNA_HUMAN
θ value	0.0563607 (rank : 167)	NC score	0.055433 (rank : 377)
Query Neighborhood Hits	345	Target Neighborhood Hits	982	Shared Neighborhood Hits	81
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNA_MOUSE
θ value	0.0563607 (rank : 168)	NC score	0.059314 (rank : 330)
Query Neighborhood Hits	345	Target Neighborhood Hits	846	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ANR26_HUMAN
θ value	0.0736092 (rank : 169)	NC score	0.058889 (rank : 332)
Query Neighborhood Hits	345	Target Neighborhood Hits	1614	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MYOM2_HUMAN
θ value	0.0736092 (rank : 170)	NC score	0.057584 (rank : 350)
Query Neighborhood Hits	345	Target Neighborhood Hits	341	Shared Neighborhood Hits	25
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

PZRN3_HUMAN
θ value	0.0736092 (rank : 171)	NC score	0.183565 (rank : 199)
Query Neighborhood Hits	345	Target Neighborhood Hits	461	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.0736092 (rank : 172)	NC score	0.184125 (rank : 197)
Query Neighborhood Hits	345	Target Neighborhood Hits	447	Shared Neighborhood Hits	161
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

UACA_MOUSE
θ value	0.0736092 (rank : 173)	NC score	0.052778 (rank : 415)
Query Neighborhood Hits	345	Target Neighborhood Hits	1620	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AKAP9_HUMAN
θ value	0.0961366 (rank : 174)	NC score	0.076669 (rank : 261)
Query Neighborhood Hits	345	Target Neighborhood Hits	1710	Shared Neighborhood Hits	130
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CHFR_HUMAN
θ value	0.0961366 (rank : 175)	NC score	0.318362 (rank : 152)
Query Neighborhood Hits	345	Target Neighborhood Hits	255	Shared Neighborhood Hits	152
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

MYH6_HUMAN
θ value	0.0961366 (rank : 176)	NC score	0.057146 (rank : 354)
Query Neighborhood Hits	345	Target Neighborhood Hits	1426	Shared Neighborhood Hits	117
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

UHRF1_HUMAN
θ value	0.0961366 (rank : 177)	NC score	0.245729 (rank : 176)
Query Neighborhood Hits	345	Target Neighborhood Hits	272	Shared Neighborhood Hits	151
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ABTAP_HUMAN
θ value	0.125558 (rank : 178)	NC score	0.058633 (rank : 338)
Query Neighborhood Hits	345	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

RABE1_HUMAN
θ value	0.125558 (rank : 179)	NC score	0.071712 (rank : 276)
Query Neighborhood Hits	345	Target Neighborhood Hits	1104	Shared Neighborhood Hits	114
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	0.125558 (rank : 180)	NC score	0.071315 (rank : 277)
Query Neighborhood Hits	345	Target Neighborhood Hits	1105	Shared Neighborhood Hits	116
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

IBRD2_MOUSE
θ value	0.163984 (rank : 181)	NC score	0.043818 (rank : 464)
Query Neighborhood Hits	345	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

LNX2_MOUSE
θ value	0.163984 (rank : 182)	NC score	0.217064 (rank : 184)
Query Neighborhood Hits	345	Target Neighborhood Hits	407	Shared Neighborhood Hits	154
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TRAF6_HUMAN
θ value	0.163984 (rank : 183)	NC score	0.263273 (rank : 166)
Query Neighborhood Hits	345	Target Neighborhood Hits	267	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF7_HUMAN
θ value	0.163984 (rank : 184)	NC score	0.161248 (rank : 209)
Query Neighborhood Hits	345	Target Neighborhood Hits	482	Shared Neighborhood Hits	153
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	0.163984 (rank : 185)	NC score	0.161614 (rank : 208)
Query Neighborhood Hits	345	Target Neighborhood Hits	470	Shared Neighborhood Hits	152
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

CF060_HUMAN
θ value	0.21417 (rank : 186)	NC score	0.073409 (rank : 271)
Query Neighborhood Hits	345	Target Neighborhood Hits	1270	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

IBRD2_HUMAN
θ value	0.21417 (rank : 187)	NC score	0.051047 (rank : 436)
Query Neighborhood Hits	345	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

MGRN1_MOUSE
θ value	0.21417 (rank : 188)	NC score	0.139178 (rank : 219)
Query Neighborhood Hits	345	Target Neighborhood Hits	149	Shared Neighborhood Hits	86
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

PML_HUMAN
θ value	0.21417 (rank : 189)	NC score	0.392275 (rank : 133)
Query Neighborhood Hits	345	Target Neighborhood Hits	248	Shared Neighborhood Hits	122
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RBBP6_HUMAN
θ value	0.21417 (rank : 190)	NC score	0.151430 (rank : 214)
Query Neighborhood Hits	345	Target Neighborhood Hits	1135	Shared Neighborhood Hits	151
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.21417 (rank : 191)	NC score	0.166607 (rank : 205)
Query Neighborhood Hits	345	Target Neighborhood Hits	1014	Shared Neighborhood Hits	148
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBCC1_MOUSE
θ value	0.21417 (rank : 192)	NC score	0.073464 (rank : 270)
Query Neighborhood Hits	345	Target Neighborhood Hits	1048	Shared Neighborhood Hits	112
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RC3H1_HUMAN
θ value	0.21417 (rank : 193)	NC score	0.197969 (rank : 192)
Query Neighborhood Hits	345	Target Neighborhood Hits	433	Shared Neighborhood Hits	129
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	0.21417 (rank : 194)	NC score	0.206165 (rank : 190)
Query Neighborhood Hits	345	Target Neighborhood Hits	244	Shared Neighborhood Hits	123
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TRI66_HUMAN
θ value	0.21417 (rank : 195)	NC score	0.252816 (rank : 173)
Query Neighborhood Hits	345	Target Neighborhood Hits	479	Shared Neighborhood Hits	87
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	0.21417 (rank : 196)	NC score	0.260047 (rank : 168)
Query Neighborhood Hits	345	Target Neighborhood Hits	491	Shared Neighborhood Hits	88
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CENPF_HUMAN
θ value	0.279714 (rank : 197)	NC score	0.078773 (rank : 256)
Query Neighborhood Hits	345	Target Neighborhood Hits	1932	Shared Neighborhood Hits	157
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MGRN1_HUMAN
θ value	0.279714 (rank : 198)	NC score	0.135306 (rank : 220)
Query Neighborhood Hits	345	Target Neighborhood Hits	192	Shared Neighborhood Hits	87
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MNAB_HUMAN
θ value	0.279714 (rank : 199)	NC score	0.174978 (rank : 202)
Query Neighborhood Hits	345	Target Neighborhood Hits	196	Shared Neighborhood Hits	99
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	0.279714 (rank : 200)	NC score	0.173351 (rank : 203)
Query Neighborhood Hits	345	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MYH11_HUMAN
θ value	0.279714 (rank : 201)	NC score	0.068371 (rank : 282)
Query Neighborhood Hits	345	Target Neighborhood Hits	1806	Shared Neighborhood Hits	147
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	0.279714 (rank : 202)	NC score	0.065527 (rank : 290)
Query Neighborhood Hits	345	Target Neighborhood Hits	1777	Shared Neighborhood Hits	142
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYO5C_HUMAN
θ value	0.279714 (rank : 203)	NC score	0.055833 (rank : 371)
Query Neighborhood Hits	345	Target Neighborhood Hits	1206	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RN183_HUMAN
θ value	0.279714 (rank : 204)	NC score	0.345393 (rank : 142)
Query Neighborhood Hits	345	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF41_HUMAN
θ value	0.279714 (rank : 205)	NC score	0.321205 (rank : 150)
Query Neighborhood Hits	345	Target Neighborhood Hits	226	Shared Neighborhood Hits	144
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

BIRC7_HUMAN
θ value	0.365318 (rank : 206)	NC score	0.212629 (rank : 189)
Query Neighborhood Hits	345	Target Neighborhood Hits	185	Shared Neighborhood Hits	137
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

PEX10_HUMAN
θ value	0.365318 (rank : 207)	NC score	0.348063 (rank : 141)
Query Neighborhood Hits	345	Target Neighborhood Hits	255	Shared Neighborhood Hits	151
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN125_MOUSE
θ value	0.365318 (rank : 208)	NC score	0.344730 (rank : 143)
Query Neighborhood Hits	345	Target Neighborhood Hits	220	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

CCD41_MOUSE
θ value	0.47712 (rank : 209)	NC score	0.067762 (rank : 283)
Query Neighborhood Hits	345	Target Neighborhood Hits	1399	Shared Neighborhood Hits	128
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DTX3_HUMAN
θ value	0.47712 (rank : 210)	NC score	0.231724 (rank : 180)
Query Neighborhood Hits	345	Target Neighborhood Hits	198	Shared Neighborhood Hits	137
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

MYOM1_MOUSE
θ value	0.47712 (rank : 211)	NC score	0.051375 (rank : 429)
Query Neighborhood Hits	345	Target Neighborhood Hits	415	Shared Neighborhood Hits	27
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

RAG1_HUMAN
θ value	0.47712 (rank : 212)	NC score	0.259049 (rank : 170)
Query Neighborhood Hits	345	Target Neighborhood Hits	203	Shared Neighborhood Hits	134
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	0.47712 (rank : 213)	NC score	0.257757 (rank : 171)
Query Neighborhood Hits	345	Target Neighborhood Hits	189	Shared Neighborhood Hits	138
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RNF41_MOUSE
θ value	0.47712 (rank : 214)	NC score	0.318779 (rank : 151)
Query Neighborhood Hits	345	Target Neighborhood Hits	224	Shared Neighborhood Hits	144
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TOPRS_HUMAN
θ value	0.47712 (rank : 215)	NC score	0.180120 (rank : 200)
Query Neighborhood Hits	345	Target Neighborhood Hits	286	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	0.47712 (rank : 216)	NC score	0.184912 (rank : 196)
Query Neighborhood Hits	345	Target Neighborhood Hits	263	Shared Neighborhood Hits	114
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI40_HUMAN
θ value	0.47712 (rank : 217)	NC score	0.513610 (rank : 99)
Query Neighborhood Hits	345	Target Neighborhood Hits	279	Shared Neighborhood Hits	184
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

AKP8L_HUMAN
θ value	0.62314 (rank : 218)	NC score	0.029617 (rank : 485)
Query Neighborhood Hits	345	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

BFAR_HUMAN
θ value	0.62314 (rank : 219)	NC score	0.351400 (rank : 139)
Query Neighborhood Hits	345	Target Neighborhood Hits	222	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

DTX3_MOUSE
θ value	0.62314 (rank : 220)	NC score	0.236671 (rank : 179)
Query Neighborhood Hits	345	Target Neighborhood Hits	202	Shared Neighborhood Hits	139
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

GOGA3_MOUSE
θ value	0.62314 (rank : 221)	NC score	0.064873 (rank : 295)
Query Neighborhood Hits	345	Target Neighborhood Hits	1437	Shared Neighborhood Hits	133
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

RN169_HUMAN
θ value	0.62314 (rank : 222)	NC score	0.281148 (rank : 159)
Query Neighborhood Hits	345	Target Neighborhood Hits	203	Shared Neighborhood Hits	114
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

CCD46_HUMAN
θ value	0.813845 (rank : 223)	NC score	0.074066 (rank : 267)
Query Neighborhood Hits	345	Target Neighborhood Hits	1430	Shared Neighborhood Hits	146
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CING_MOUSE
θ value	0.813845 (rank : 224)	NC score	0.059620 (rank : 326)
Query Neighborhood Hits	345	Target Neighborhood Hits	1432	Shared Neighborhood Hits	117
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CYTSA_HUMAN
θ value	0.813845 (rank : 225)	NC score	0.061118 (rank : 313)
Query Neighborhood Hits	345	Target Neighborhood Hits	1138	Shared Neighborhood Hits	115
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

LZTS2_MOUSE
θ value	0.813845 (rank : 226)	NC score	0.053591 (rank : 405)
Query Neighborhood Hits	345	Target Neighborhood Hits	423	Shared Neighborhood Hits	65
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

MOES_HUMAN
θ value	0.813845 (rank : 227)	NC score	0.040780 (rank : 471)
Query Neighborhood Hits	345	Target Neighborhood Hits	892	Shared Neighborhood Hits	97
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RN185_HUMAN
θ value	0.813845 (rank : 228)	NC score	0.268106 (rank : 164)
Query Neighborhood Hits	345	Target Neighborhood Hits	213	Shared Neighborhood Hits	141
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	0.813845 (rank : 229)	NC score	0.267656 (rank : 165)
Query Neighborhood Hits	345	Target Neighborhood Hits	211	Shared Neighborhood Hits	141
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TPR_HUMAN
θ value	0.813845 (rank : 230)	NC score	0.062514 (rank : 306)
Query Neighborhood Hits	345	Target Neighborhood Hits	1921	Shared Neighborhood Hits	145
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ABTAP_MOUSE
θ value	1.06291 (rank : 231)	NC score	0.045943 (rank : 458)
Query Neighborhood Hits	345	Target Neighborhood Hits	381	Shared Neighborhood Hits	49
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

BFAR_MOUSE
θ value	1.06291 (rank : 232)	NC score	0.333195 (rank : 148)
Query Neighborhood Hits	345	Target Neighborhood Hits	232	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

CP135_HUMAN
θ value	1.06291 (rank : 233)	NC score	0.057493 (rank : 351)
Query Neighborhood Hits	345	Target Neighborhood Hits	1290	Shared Neighborhood Hits	112
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DTBP1_HUMAN
θ value	1.06291 (rank : 234)	NC score	0.044652 (rank : 462)
Query Neighborhood Hits	345	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

MRCKB_HUMAN
θ value	1.06291 (rank : 235)	NC score	0.021195 (rank : 495)
Query Neighborhood Hits	345	Target Neighborhood Hits	2239	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYH6_MOUSE
θ value	1.06291 (rank : 236)	NC score	0.056387 (rank : 365)
Query Neighborhood Hits	345	Target Neighborhood Hits	1501	Shared Neighborhood Hits	129
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

RNF5_HUMAN
θ value	1.06291 (rank : 237)	NC score	0.253755 (rank : 172)
Query Neighborhood Hits	345	Target Neighborhood Hits	206	Shared Neighborhood Hits	137
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	1.06291 (rank : 238)	NC score	0.252070 (rank : 174)
Query Neighborhood Hits	345	Target Neighborhood Hits	206	Shared Neighborhood Hits	136
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

AKP8L_MOUSE
θ value	1.38821 (rank : 239)	NC score	0.026437 (rank : 489)
Query Neighborhood Hits	345	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

ATS2_HUMAN
θ value	1.38821 (rank : 240)	NC score	0.003825 (rank : 504)
Query Neighborhood Hits	345	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

BRE1B_HUMAN
θ value	1.38821 (rank : 241)	NC score	0.119400 (rank : 235)
Query Neighborhood Hits	345	Target Neighborhood Hits	1040	Shared Neighborhood Hits	205
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	1.38821 (rank : 242)	NC score	0.122213 (rank : 231)
Query Neighborhood Hits	345	Target Neighborhood Hits	970	Shared Neighborhood Hits	204
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CYTSA_MOUSE
θ value	1.38821 (rank : 243)	NC score	0.058747 (rank : 334)
Query Neighborhood Hits	345	Target Neighborhood Hits	1104	Shared Neighborhood Hits	113
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DZIP1_HUMAN
θ value	1.38821 (rank : 244)	NC score	0.048888 (rank : 451)
Query Neighborhood Hits	345	Target Neighborhood Hits	675	Shared Neighborhood Hits	66
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

KIF4A_HUMAN
θ value	1.38821 (rank : 245)	NC score	0.035142 (rank : 479)
Query Neighborhood Hits	345	Target Neighborhood Hits	1159	Shared Neighborhood Hits	102
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MYH3_HUMAN
θ value	1.38821 (rank : 246)	NC score	0.057462 (rank : 352)
Query Neighborhood Hits	345	Target Neighborhood Hits	1660	Shared Neighborhood Hits	134
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

R113B_HUMAN
θ value	1.38821 (rank : 247)	NC score	0.246958 (rank : 175)
Query Neighborhood Hits	345	Target Neighborhood Hits	165	Shared Neighborhood Hits	124
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RN125_HUMAN
θ value	1.38821 (rank : 248)	NC score	0.342936 (rank : 144)
Query Neighborhood Hits	345	Target Neighborhood Hits	230	Shared Neighborhood Hits	152
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN183_MOUSE
θ value	1.38821 (rank : 249)	NC score	0.299918 (rank : 157)
Query Neighborhood Hits	345	Target Neighborhood Hits	119	Shared Neighborhood Hits	104
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

SDPR_MOUSE
θ value	1.38821 (rank : 250)	NC score	0.049442 (rank : 450)
Query Neighborhood Hits	345	Target Neighborhood Hits	485	Shared Neighborhood Hits	72
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SYNE1_HUMAN
θ value	1.38821 (rank : 251)	NC score	0.056929 (rank : 359)
Query Neighborhood Hits	345	Target Neighborhood Hits	1484	Shared Neighborhood Hits	124
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TNAP3_HUMAN
θ value	1.38821 (rank : 252)	NC score	0.011243 (rank : 501)
Query Neighborhood Hits	345	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

UHRF1_MOUSE
θ value	1.38821 (rank : 253)	NC score	0.226431 (rank : 181)
Query Neighborhood Hits	345	Target Neighborhood Hits	278	Shared Neighborhood Hits	147
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

BRE1A_HUMAN
θ value	1.81305 (rank : 254)	NC score	0.106141 (rank : 245)
Query Neighborhood Hits	345	Target Neighborhood Hits	1071	Shared Neighborhood Hits	202
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	1.81305 (rank : 255)	NC score	0.105681 (rank : 246)
Query Neighborhood Hits	345	Target Neighborhood Hits	1025	Shared Neighborhood Hits	198
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CE290_HUMAN
θ value	1.81305 (rank : 256)	NC score	0.075217 (rank : 265)
Query Neighborhood Hits	345	Target Neighborhood Hits	1553	Shared Neighborhood Hits	142
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CING_HUMAN
θ value	1.81305 (rank : 257)	NC score	0.061185 (rank : 312)
Query Neighborhood Hits	345	Target Neighborhood Hits	1275	Shared Neighborhood Hits	111
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

LAMA4_HUMAN
θ value	1.81305 (rank : 258)	NC score	0.028398 (rank : 486)
Query Neighborhood Hits	345	Target Neighborhood Hits	708	Shared Neighborhood Hits	76
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MRCKB_MOUSE
θ value	1.81305 (rank : 259)	NC score	0.021072 (rank : 496)
Query Neighborhood Hits	345	Target Neighborhood Hits	2180	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYH10_HUMAN
θ value	1.81305 (rank : 260)	NC score	0.064331 (rank : 299)
Query Neighborhood Hits	345	Target Neighborhood Hits	1620	Shared Neighborhood Hits	142
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH13_HUMAN
θ value	1.81305 (rank : 261)	NC score	0.057104 (rank : 355)
Query Neighborhood Hits	345	Target Neighborhood Hits	1504	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

RKHD1_HUMAN
θ value	1.81305 (rank : 262)	NC score	0.123784 (rank : 228)
Query Neighborhood Hits	345	Target Neighborhood Hits	163	Shared Neighborhood Hits	67
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN141_HUMAN
θ value	1.81305 (rank : 263)	NC score	0.243931 (rank : 178)
Query Neighborhood Hits	345	Target Neighborhood Hits	199	Shared Neighborhood Hits	133
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	1.81305 (rank : 264)	NC score	0.244134 (rank : 177)
Query Neighborhood Hits	345	Target Neighborhood Hits	200	Shared Neighborhood Hits	134
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	1.81305 (rank : 265)	NC score	0.261365 (rank : 167)
Query Neighborhood Hits	345	Target Neighborhood Hits	162	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	1.81305 (rank : 266)	NC score	0.259621 (rank : 169)
Query Neighborhood Hits	345	Target Neighborhood Hits	161	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

SMRA3_MOUSE
θ value	1.81305 (rank : 267)	NC score	0.190500 (rank : 194)
Query Neighborhood Hits	345	Target Neighborhood Hits	267	Shared Neighborhood Hits	156
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TLR2_HUMAN
θ value	1.81305 (rank : 268)	NC score	0.001819 (rank : 507)
Query Neighborhood Hits	345	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

CN004_HUMAN
θ value	2.36792 (rank : 269)	NC score	0.038368 (rank : 475)
Query Neighborhood Hits	345	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

CN004_MOUSE
θ value	2.36792 (rank : 270)	NC score	0.037514 (rank : 476)
Query Neighborhood Hits	345	Target Neighborhood Hits	105	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

CP135_MOUSE
θ value	2.36792 (rank : 271)	NC score	0.058838 (rank : 333)
Query Neighborhood Hits	345	Target Neighborhood Hits	1278	Shared Neighborhood Hits	114
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP250_HUMAN
θ value	2.36792 (rank : 272)	NC score	0.066929 (rank : 286)
Query Neighborhood Hits	345	Target Neighborhood Hits	1805	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DNMBP_HUMAN
θ value	2.36792 (rank : 273)	NC score	0.007554 (rank : 503)
Query Neighborhood Hits	345	Target Neighborhood Hits	413	Shared Neighborhood Hits	20
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

HOOK1_HUMAN
θ value	2.36792 (rank : 274)	NC score	0.055459 (rank : 376)
Query Neighborhood Hits	345	Target Neighborhood Hits	942	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MIB1_HUMAN
θ value	2.36792 (rank : 275)	NC score	0.056958 (rank : 358)
Query Neighborhood Hits	345	Target Neighborhood Hits	470	Shared Neighborhood Hits	100
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	2.36792 (rank : 276)	NC score	0.056816 (rank : 362)
Query Neighborhood Hits	345	Target Neighborhood Hits	471	Shared Neighborhood Hits	101
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MOES_MOUSE
θ value	2.36792 (rank : 277)	NC score	0.042047 (rank : 466)
Query Neighborhood Hits	345	Target Neighborhood Hits	923	Shared Neighborhood Hits	99
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PLCB3_MOUSE
θ value	2.36792 (rank : 278)	NC score	0.031356 (rank : 484)
Query Neighborhood Hits	345	Target Neighborhood Hits	344	Shared Neighborhood Hits	52
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PTPRF_HUMAN
θ value	2.36792 (rank : 279)	NC score	0.016172 (rank : 499)
Query Neighborhood Hits	345	Target Neighborhood Hits	489	Shared Neighborhood Hits	23
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

R113A_HUMAN
θ value	2.36792 (rank : 280)	NC score	0.212870 (rank : 188)
Query Neighborhood Hits	345	Target Neighborhood Hits	177	Shared Neighborhood Hits	120
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RADI_HUMAN
θ value	2.36792 (rank : 281)	NC score	0.036702 (rank : 477)
Query Neighborhood Hits	345	Target Neighborhood Hits	741	Shared Neighborhood Hits	89
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RAI14_HUMAN
θ value	2.36792 (rank : 282)	NC score	0.042453 (rank : 465)
Query Neighborhood Hits	345	Target Neighborhood Hits	1367	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ROBO3_HUMAN
θ value	2.36792 (rank : 283)	NC score	0.024876 (rank : 492)
Query Neighborhood Hits	345	Target Neighborhood Hits	570	Shared Neighborhood Hits	22
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

ROBO3_MOUSE
θ value	2.36792 (rank : 284)	NC score	0.027626 (rank : 487)
Query Neighborhood Hits	345	Target Neighborhood Hits	524	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

SMRA3_HUMAN
θ value	2.36792 (rank : 285)	NC score	0.202220 (rank : 191)
Query Neighborhood Hits	345	Target Neighborhood Hits	265	Shared Neighborhood Hits	165
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

ANR26_MOUSE
θ value	3.0926 (rank : 286)	NC score	0.047884 (rank : 452)
Query Neighborhood Hits	345	Target Neighborhood Hits	1554	Shared Neighborhood Hits	123
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BIRC8_HUMAN
θ value	3.0926 (rank : 287)	NC score	0.108300 (rank : 241)
Query Neighborhood Hits	345	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

RADI_MOUSE
θ value	3.0926 (rank : 288)	NC score	0.038676 (rank : 474)
Query Neighborhood Hits	345	Target Neighborhood Hits	773	Shared Neighborhood Hits	88
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

RNF26_HUMAN
θ value	3.0926 (rank : 289)	NC score	0.122233 (rank : 230)
Query Neighborhood Hits	345	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

SPFH1_HUMAN
θ value	3.0926 (rank : 290)	NC score	0.016240 (rank : 498)
Query Neighborhood Hits	345	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	O75477	Gene names	SPFH1, C10orf69, KE04, KEO4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (Protein KE04).

CUTL1_HUMAN
θ value	4.03905 (rank : 291)	NC score	0.050056 (rank : 449)
Query Neighborhood Hits	345	Target Neighborhood Hits	1574	Shared Neighborhood Hits	118
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DMD_HUMAN
θ value	4.03905 (rank : 292)	NC score	0.045424 (rank : 459)
Query Neighborhood Hits	345	Target Neighborhood Hits	1135	Shared Neighborhood Hits	108
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

GOGA2_MOUSE
θ value	4.03905 (rank : 293)	NC score	0.058683 (rank : 337)
Query Neighborhood Hits	345	Target Neighborhood Hits	944	Shared Neighborhood Hits	105
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA4_MOUSE
θ value	4.03905 (rank : 294)	NC score	0.073078 (rank : 274)
Query Neighborhood Hits	345	Target Neighborhood Hits	1939	Shared Neighborhood Hits	157
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LZTS2_HUMAN
θ value	4.03905 (rank : 295)	NC score	0.047615 (rank : 454)
Query Neighborhood Hits	345	Target Neighborhood Hits	427	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

MYH10_MOUSE
θ value	4.03905 (rank : 296)	NC score	0.063750 (rank : 301)
Query Neighborhood Hits	345	Target Neighborhood Hits	1612	Shared Neighborhood Hits	140
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

BIRC2_HUMAN
θ value	5.27518 (rank : 297)	NC score	0.065199 (rank : 292)
Query Neighborhood Hits	345	Target Neighborhood Hits	142	Shared Neighborhood Hits	85
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BPAEA_HUMAN
θ value	5.27518 (rank : 298)	NC score	0.046537 (rank : 456)
Query Neighborhood Hits	345	Target Neighborhood Hits	1369	Shared Neighborhood Hits	120
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	5.27518 (rank : 299)	NC score	0.054204 (rank : 396)
Query Neighborhood Hits	345	Target Neighborhood Hits	1480	Shared Neighborhood Hits	129
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD43_HUMAN
θ value	5.27518 (rank : 300)	NC score	0.024518 (rank : 493)
Query Neighborhood Hits	345	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q96MW1	Gene names	CCDC43
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

HOME1_HUMAN
θ value	5.27518 (rank : 301)	NC score	0.043915 (rank : 463)
Query Neighborhood Hits	345	Target Neighborhood Hits	564	Shared Neighborhood Hits	78
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

MYH4_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.058193 (rank : 343)
Query Neighborhood Hits	345	Target Neighborhood Hits	1377	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

PLDN_MOUSE
θ value	5.27518 (rank : 303)	NC score	0.031972 (rank : 481)
Query Neighborhood Hits	345	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0C0, Q3TUT4, Q91VG4	Gene names	Pldn, P2, Pa
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein) (Syntaxin 13-interacting protein).

RNF34_HUMAN
θ value	5.27518 (rank : 304)	NC score	0.078634 (rank : 257)
Query Neighborhood Hits	345	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	5.27518 (rank : 305)	NC score	0.080051 (rank : 255)
Query Neighborhood Hits	345	Target Neighborhood Hits	160	Shared Neighborhood Hits	81
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RPGR1_HUMAN
θ value	5.27518 (rank : 306)	NC score	0.046777 (rank : 455)
Query Neighborhood Hits	345	Target Neighborhood Hits	578	Shared Neighborhood Hits	72
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

TEX28_HUMAN
θ value	5.27518 (rank : 307)	NC score	0.019860 (rank : 497)
Query Neighborhood Hits	345	Target Neighborhood Hits	62	Shared Neighborhood Hits	16
SwissProt Accessions	O15482	Gene names	CXorf2, TEX28
Domain Architecture	No domain graphic available
Description	Testis-specific protein TEX28.

UB7I4_MOUSE
θ value	5.27518 (rank : 308)	NC score	0.031644 (rank : 482)
Query Neighborhood Hits	345	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ASPP2_HUMAN
θ value	6.88961 (rank : 309)	NC score	0.024114 (rank : 494)
Query Neighborhood Hits	345	Target Neighborhood Hits	1156	Shared Neighborhood Hits	90
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CBLB_HUMAN
θ value	6.88961 (rank : 310)	NC score	0.108153 (rank : 243)
Query Neighborhood Hits	345	Target Neighborhood Hits	261	Shared Neighborhood Hits	129
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	6.88961 (rank : 311)	NC score	0.108448 (rank : 240)
Query Neighborhood Hits	345	Target Neighborhood Hits	277	Shared Neighborhood Hits	129
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CENPE_HUMAN
θ value	6.88961 (rank : 312)	NC score	0.060945 (rank : 314)
Query Neighborhood Hits	345	Target Neighborhood Hits	2060	Shared Neighborhood Hits	156
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CTGE2_HUMAN
θ value	6.88961 (rank : 313)	NC score	0.045142 (rank : 460)
Query Neighborhood Hits	345	Target Neighborhood Hits	594	Shared Neighborhood Hits	83
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

CUTL1_MOUSE
θ value	6.88961 (rank : 314)	NC score	0.044893 (rank : 461)
Query Neighborhood Hits	345	Target Neighborhood Hits	1620	Shared Neighborhood Hits	113
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

EPHA8_HUMAN
θ value	6.88961 (rank : 315)	NC score	-0.002065 (rank : 510)
Query Neighborhood Hits	345	Target Neighborhood Hits	956	Shared Neighborhood Hits	21
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	6.88961 (rank : 316)	NC score	-0.002079 (rank : 511)
Query Neighborhood Hits	345	Target Neighborhood Hits	969	Shared Neighborhood Hits	21
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

HOME1_MOUSE
θ value	6.88961 (rank : 317)	NC score	0.040067 (rank : 473)
Query Neighborhood Hits	345	Target Neighborhood Hits	630	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

HOOK2_MOUSE
θ value	6.88961 (rank : 318)	NC score	0.041592 (rank : 468)
Query Neighborhood Hits	345	Target Neighborhood Hits	736	Shared Neighborhood Hits	85
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

MYO5A_HUMAN
θ value	6.88961 (rank : 319)	NC score	0.053557 (rank : 407)
Query Neighborhood Hits	345	Target Neighborhood Hits	1092	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

PCGF4_HUMAN
θ value	6.88961 (rank : 320)	NC score	0.126531 (rank : 226)
Query Neighborhood Hits	345	Target Neighborhood Hits	161	Shared Neighborhood Hits	103
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	6.88961 (rank : 321)	NC score	0.126875 (rank : 225)
Query Neighborhood Hits	345	Target Neighborhood Hits	163	Shared Neighborhood Hits	102
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PHF14_MOUSE
θ value	6.88961 (rank : 322)	NC score	0.032718 (rank : 480)
Query Neighborhood Hits	345	Target Neighborhood Hits	342	Shared Neighborhood Hits	56
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PLDN_HUMAN
θ value	6.88961 (rank : 323)	NC score	0.031472 (rank : 483)
Query Neighborhood Hits	345	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UL45	Gene names	PLDN, PA
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein).

RRBP1_HUMAN
θ value	6.88961 (rank : 324)	NC score	0.046414 (rank : 457)
Query Neighborhood Hits	345	Target Neighborhood Hits	1306	Shared Neighborhood Hits	107
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SDPR_HUMAN
θ value	6.88961 (rank : 325)	NC score	0.040823 (rank : 470)
Query Neighborhood Hits	345	Target Neighborhood Hits	337	Shared Neighborhood Hits	60
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SPAT2_HUMAN
θ value	6.88961 (rank : 326)	NC score	0.035349 (rank : 478)
Query Neighborhood Hits	345	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

ZFP14_HUMAN
θ value	6.88961 (rank : 327)	NC score	-0.010260 (rank : 512)
Query Neighborhood Hits	345	Target Neighborhood Hits	743	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCL3	Gene names	ZFP14, KIAA1559
Domain Architecture
Description	Zinc finger protein 14 homolog (Zfp-14).

BICD1_MOUSE
θ value	8.99809 (rank : 328)	NC score	0.050081 (rank : 448)
Query Neighborhood Hits	345	Target Neighborhood Hits	837	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CBL_HUMAN
θ value	8.99809 (rank : 329)	NC score	0.110227 (rank : 238)
Query Neighborhood Hits	345	Target Neighborhood Hits	353	Shared Neighborhood Hits	131
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	8.99809 (rank : 330)	NC score	0.108238 (rank : 242)
Query Neighborhood Hits	345	Target Neighborhood Hits	426	Shared Neighborhood Hits	136
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CCD11_HUMAN
θ value	8.99809 (rank : 331)	NC score	0.057606 (rank : 349)
Query Neighborhood Hits	345	Target Neighborhood Hits	822	Shared Neighborhood Hits	100
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD27_HUMAN
θ value	8.99809 (rank : 332)	NC score	0.053014 (rank : 414)
Query Neighborhood Hits	345	Target Neighborhood Hits	594	Shared Neighborhood Hits	82
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CNTN6_HUMAN
θ value	8.99809 (rank : 333)	NC score	0.010214 (rank : 502)
Query Neighborhood Hits	345	Target Neighborhood Hits	422	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

HDAC4_HUMAN
θ value	8.99809 (rank : 334)	NC score	0.011743 (rank : 500)
Query Neighborhood Hits	345	Target Neighborhood Hits	390	Shared Neighborhood Hits	53
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

MYH8_MOUSE
θ value	8.99809 (rank : 335)	NC score	0.056992 (rank : 357)
Query Neighborhood Hits	345	Target Neighborhood Hits	1600	Shared Neighborhood Hits	136
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PIAS2_MOUSE
θ value	8.99809 (rank : 336)	NC score	0.002310 (rank : 505)
Query Neighborhood Hits	345	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5D8, O54987, Q8C384, Q8CDQ8, Q8K208, Q99JX5, Q9D5W7, Q9QZ63	Gene names	Pias2, Miz1, Piasx
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3).

PPIP2_HUMAN
θ value	8.99809 (rank : 337)	NC score	0.025022 (rank : 490)
Query Neighborhood Hits	345	Target Neighborhood Hits	254	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

SAS6_HUMAN
θ value	8.99809 (rank : 338)	NC score	0.047651 (rank : 453)
Query Neighborhood Hits	345	Target Neighborhood Hits	791	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SH3G3_HUMAN
θ value	8.99809 (rank : 339)	NC score	0.001905 (rank : 506)
Query Neighborhood Hits	345	Target Neighborhood Hits	222	Shared Neighborhood Hits	10
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SIAH2_HUMAN
θ value	8.99809 (rank : 340)	NC score	0.064658 (rank : 296)
Query Neighborhood Hits	345	Target Neighborhood Hits	94	Shared Neighborhood Hits	48
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	8.99809 (rank : 341)	NC score	0.062890 (rank : 304)
Query Neighborhood Hits	345	Target Neighborhood Hits	101	Shared Neighborhood Hits	47
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

TLR2_MOUSE
θ value	8.99809 (rank : 342)	NC score	-0.000151 (rank : 508)
Query Neighborhood Hits	345	Target Neighborhood Hits	283	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QUN7, Q3U400, Q9DBC4	Gene names	Tlr2
Domain Architecture
Description	Toll-like receptor 2 precursor (CD282 antigen).

TLR5_MOUSE
θ value	8.99809 (rank : 343)	NC score	-0.001518 (rank : 509)
Query Neighborhood Hits	345	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLF7	Gene names	Tlr5
Domain Architecture
Description	Toll-like receptor 5 precursor.

UB7I4_HUMAN
θ value	8.99809 (rank : 344)	NC score	0.024994 (rank : 491)
Query Neighborhood Hits	345	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ZN645_HUMAN
θ value	8.99809 (rank : 345)	NC score	0.040631 (rank : 472)
Query Neighborhood Hits	345	Target Neighborhood Hits	265	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

AIRE_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.060655 (rank : 316)
Query Neighborhood Hits	345	Target Neighborhood Hits	144	Shared Neighborhood Hits	14
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.059778 (rank : 324)
Query Neighborhood Hits	345	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AMFR2_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.120605 (rank : 232)
Query Neighborhood Hits	345	Target Neighborhood Hits	219	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.119590 (rank : 234)
Query Neighborhood Hits	345	Target Neighborhood Hits	208	Shared Neighborhood Hits	108
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ARI2_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.052533 (rank : 419)
Query Neighborhood Hits	345	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.050864 (rank : 439)
Query Neighborhood Hits	345	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

AZI1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.055906 (rank : 370)
Query Neighborhood Hits	345	Target Neighborhood Hits	1000	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.056072 (rank : 368)
Query Neighborhood Hits	345	Target Neighborhood Hits	990	Shared Neighborhood Hits	106
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BARD1_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.081852 (rank : 253)
Query Neighborhood Hits	345	Target Neighborhood Hits	427	Shared Neighborhood Hits	92
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.077329 (rank : 259)
Query Neighborhood Hits	345	Target Neighborhood Hits	411	Shared Neighborhood Hits	90
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.057899 (rank : 345)
Query Neighborhood Hits	345	Target Neighborhood Hits	693	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.055126 (rank : 383)
Query Neighborhood Hits	345	Target Neighborhood Hits	780	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.062632 (rank : 305)
Query Neighborhood Hits	345	Target Neighborhood Hits	803	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BIRC2_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.052669 (rank : 417)
Query Neighborhood Hits	345	Target Neighborhood Hits	137	Shared Neighborhood Hits	78
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.058312 (rank : 341)
Query Neighborhood Hits	345	Target Neighborhood Hits	133	Shared Neighborhood Hits	77
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BRAP_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.073887 (rank : 268)
Query Neighborhood Hits	345	Target Neighborhood Hits	560	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.064909 (rank : 294)
Query Neighborhood Hits	345	Target Neighborhood Hits	409	Shared Neighborhood Hits	100
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BT3A2_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.152291 (rank : 213)
Query Neighborhood Hits	345	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BTNL1_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.144588 (rank : 217)
Query Neighborhood Hits	345	Target Neighborhood Hits	151	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

BTNL2_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.139247 (rank : 218)
Query Neighborhood Hits	345	Target Neighborhood Hits	164	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

CALD1_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.050606 (rank : 443)
Query Neighborhood Hits	345	Target Neighborhood Hits	959	Shared Neighborhood Hits	97
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CASP_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.053606 (rank : 404)
Query Neighborhood Hits	345	Target Neighborhood Hits	1131	Shared Neighborhood Hits	112
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.054493 (rank : 393)
Query Neighborhood Hits	345	Target Neighborhood Hits	1152	Shared Neighborhood Hits	112
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CBLC_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.106165 (rank : 244)
Query Neighborhood Hits	345	Target Neighborhood Hits	173	Shared Neighborhood Hits	108
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.109004 (rank : 239)
Query Neighborhood Hits	345	Target Neighborhood Hits	186	Shared Neighborhood Hits	113
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CCD11_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.055315 (rank : 380)
Query Neighborhood Hits	345	Target Neighborhood Hits	498	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD39_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.050558 (rank : 444)
Query Neighborhood Hits	345	Target Neighborhood Hits	868	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.051264 (rank : 431)
Query Neighborhood Hits	345	Target Neighborhood Hits	1026	Shared Neighborhood Hits	101
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.057061 (rank : 356)
Query Neighborhood Hits	345	Target Neighborhood Hits	1139	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD46_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.060468 (rank : 317)
Query Neighborhood Hits	345	Target Neighborhood Hits	1405	Shared Neighborhood Hits	135
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CD276_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.075897 (rank : 263)
Query Neighborhood Hits	345	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.081784 (rank : 254)
Query Neighborhood Hits	345	Target Neighborhood Hits	243	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD86_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.061701 (rank : 307)
Query Neighborhood Hits	345	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

CD86_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.055674 (rank : 375)
Query Neighborhood Hits	345	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

CE152_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.053862 (rank : 403)
Query Neighborhood Hits	345	Target Neighborhood Hits	976	Shared Neighborhood Hits	102
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CEP55_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.052110 (rank : 423)
Query Neighborhood Hits	345	Target Neighborhood Hits	693	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP63_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.058614 (rank : 339)
Query Neighborhood Hits	345	Target Neighborhood Hits	1005	Shared Neighborhood Hits	112
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CI039_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.051098 (rank : 434)
Query Neighborhood Hits	345	Target Neighborhood Hits	1171	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.053998 (rank : 399)
Query Neighborhood Hits	345	Target Neighborhood Hits	1088	Shared Neighborhood Hits	107
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CJ118_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.050719 (rank : 442)
Query Neighborhood Hits	345	Target Neighborhood Hits	1132	Shared Neighborhood Hits	104
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CK5P2_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.050820 (rank : 440)
Query Neighborhood Hits	345	Target Neighborhood Hits	1433	Shared Neighborhood Hits	118
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CM007_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.146792 (rank : 216)
Query Neighborhood Hits	345	Target Neighborhood Hits	422	Shared Neighborhood Hits	161
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.163058 (rank : 207)
Query Neighborhood Hits	345	Target Neighborhood Hits	416	Shared Neighborhood Hits	155
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CN145_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.053918 (rank : 401)
Query Neighborhood Hits	345	Target Neighborhood Hits	1196	Shared Neighborhood Hits	118
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CN145_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.053530 (rank : 408)
Query Neighborhood Hits	345	Target Neighborhood Hits	916	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CNOT4_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.058692 (rank : 336)
Query Neighborhood Hits	345	Target Neighborhood Hits	207	Shared Neighborhood Hits	38
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.055421 (rank : 378)
Query Neighborhood Hits	345	Target Neighborhood Hits	277	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CP250_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.064368 (rank : 298)
Query Neighborhood Hits	345	Target Neighborhood Hits	1583	Shared Neighborhood Hits	138
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CROCC_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.055756 (rank : 373)
Query Neighborhood Hits	345	Target Neighborhood Hits	1409	Shared Neighborhood Hits	125
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.053476 (rank : 409)
Query Neighborhood Hits	345	Target Neighborhood Hits	1460	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CT096_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.050323 (rank : 445)
Query Neighborhood Hits	345	Target Neighborhood Hits	438	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CYLN2_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.050865 (rank : 438)
Query Neighborhood Hits	345	Target Neighborhood Hits	1002	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DESP_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.054032 (rank : 398)
Query Neighborhood Hits	345	Target Neighborhood Hits	1470	Shared Neighborhood Hits	122
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DTX3L_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.130560 (rank : 223)
Query Neighborhood Hits	345	Target Neighborhood Hits	187	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DZIP3_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.061285 (rank : 311)
Query Neighborhood Hits	345	Target Neighborhood Hits	399	Shared Neighborhood Hits	105
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.061353 (rank : 310)
Query Neighborhood Hits	345	Target Neighborhood Hits	414	Shared Neighborhood Hits	109
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

EP15R_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.051040 (rank : 437)
Query Neighborhood Hits	345	Target Neighborhood Hits	1083	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

ERC2_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.052011 (rank : 425)
Query Neighborhood Hits	345	Target Neighborhood Hits	1156	Shared Neighborhood Hits	105
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.051485 (rank : 427)
Query Neighborhood Hits	345	Target Neighborhood Hits	1166	Shared Neighborhood Hits	104
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

FLIP1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.055400 (rank : 379)
Query Neighborhood Hits	345	Target Neighborhood Hits	1405	Shared Neighborhood Hits	127
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.056893 (rank : 360)
Query Neighborhood Hits	345	Target Neighborhood Hits	1176	Shared Neighborhood Hits	112
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FSD1L_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.270750 (rank : 162)
Query Neighborhood Hits	345	Target Neighborhood Hits	57	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.313833 (rank : 154)
Query Neighborhood Hits	345	Target Neighborhood Hits	78	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GCC1_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.060161 (rank : 320)
Query Neighborhood Hits	345	Target Neighborhood Hits	887	Shared Neighborhood Hits	105
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.054984 (rank : 385)
Query Neighborhood Hits	345	Target Neighborhood Hits	777	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC2_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.065136 (rank : 293)
Query Neighborhood Hits	345	Target Neighborhood Hits	1558	Shared Neighborhood Hits	149
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GCC2_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.064061 (rank : 300)
Query Neighborhood Hits	345	Target Neighborhood Hits	1619	Shared Neighborhood Hits	147
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA1_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.054047 (rank : 397)
Query Neighborhood Hits	345	Target Neighborhood Hits	1222	Shared Neighborhood Hits	115
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA3_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.056789 (rank : 363)
Query Neighborhood Hits	345	Target Neighborhood Hits	1317	Shared Neighborhood Hits	120
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GRAP1_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.051130 (rank : 433)
Query Neighborhood Hits	345	Target Neighborhood Hits	1234	Shared Neighborhood Hits	117
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HHLA2_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.060773 (rank : 315)
Query Neighborhood Hits	345	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

HMMR_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.055049 (rank : 384)
Query Neighborhood Hits	345	Target Neighborhood Hits	1082	Shared Neighborhood Hits	108
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.059200 (rank : 331)
Query Neighborhood Hits	345	Target Neighborhood Hits	1178	Shared Neighborhood Hits	120
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOOK1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.050723 (rank : 441)
Query Neighborhood Hits	345	Target Neighborhood Hits	910	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

ICOSL_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.068864 (rank : 279)
Query Neighborhood Hits	345	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

ICOSL_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.055919 (rank : 369)
Query Neighborhood Hits	345	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

IFT74_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.063145 (rank : 302)
Query Neighborhood Hits	345	Target Neighborhood Hits	939	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.054599 (rank : 392)
Query Neighborhood Hits	345	Target Neighborhood Hits	893	Shared Neighborhood Hits	102
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

KTN1_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.057880 (rank : 346)
Query Neighborhood Hits	345	Target Neighborhood Hits	1197	Shared Neighborhood Hits	117
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.058727 (rank : 335)
Query Neighborhood Hits	345	Target Neighborhood Hits	1324	Shared Neighborhood Hits	127
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LRSM1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.054920 (rank : 386)
Query Neighborhood Hits	345	Target Neighborhood Hits	1078	Shared Neighborhood Hits	158
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LY10_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.072662 (rank : 275)
Query Neighborhood Hits	345	Target Neighborhood Hits	151	Shared Neighborhood Hits	15
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MAT1_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.066463 (rank : 289)
Query Neighborhood Hits	345	Target Neighborhood Hits	179	Shared Neighborhood Hits	64
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.067666 (rank : 284)
Query Neighborhood Hits	345	Target Neighborhood Hits	217	Shared Neighborhood Hits	71
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MOG_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.134650 (rank : 221)
Query Neighborhood Hits	345	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.133789 (rank : 222)
Query Neighborhood Hits	345	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MY18A_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.055265 (rank : 382)
Query Neighborhood Hits	345	Target Neighborhood Hits	1929	Shared Neighborhood Hits	142
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.053242 (rank : 411)
Query Neighborhood Hits	345	Target Neighborhood Hits	1989	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH14_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.052754 (rank : 416)
Query Neighborhood Hits	345	Target Neighborhood Hits	995	Shared Neighborhood Hits	100
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.057790 (rank : 347)
Query Neighborhood Hits	345	Target Neighborhood Hits	1225	Shared Neighborhood Hits	116
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.057943 (rank : 344)
Query Neighborhood Hits	345	Target Neighborhood Hits	1478	Shared Neighborhood Hits	126
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.056844 (rank : 361)
Query Neighborhood Hits	345	Target Neighborhood Hits	1461	Shared Neighborhood Hits	124
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.056253 (rank : 366)
Query Neighborhood Hits	345	Target Neighborhood Hits	1491	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH4_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.056218 (rank : 367)
Query Neighborhood Hits	345	Target Neighborhood Hits	1476	Shared Neighborhood Hits	129
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.059859 (rank : 323)
Query Neighborhood Hits	345	Target Neighborhood Hits	1610	Shared Neighborhood Hits	131
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NEMO_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.050123 (rank : 447)
Query Neighborhood Hits	345	Target Neighborhood Hits	658	Shared Neighborhood Hits	89
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NHLC1_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.157303 (rank : 212)
Query Neighborhood Hits	345	Target Neighborhood Hits	91	Shared Neighborhood Hits	66
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.175767 (rank : 201)
Query Neighborhood Hits	345	Target Neighborhood Hits	103	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NIN_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.059588 (rank : 327)
Query Neighborhood Hits	345	Target Neighborhood Hits	1376	Shared Neighborhood Hits	121
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NUMA1_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.059708 (rank : 325)
Query Neighborhood Hits	345	Target Neighborhood Hits	1523	Shared Neighborhood Hits	131
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

OFD1_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.057292 (rank : 353)
Query Neighborhood Hits	345	Target Neighborhood Hits	753	Shared Neighborhood Hits	86
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

PCGF2_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.126941 (rank : 224)
Query Neighborhood Hits	345	Target Neighborhood Hits	222	Shared Neighborhood Hits	103
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.123764 (rank : 229)
Query Neighborhood Hits	345	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF6_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.160831 (rank : 210)
Query Neighborhood Hits	345	Target Neighborhood Hits	178	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.164071 (rank : 206)
Query Neighborhood Hits	345	Target Neighborhood Hits	163	Shared Neighborhood Hits	112
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCNT_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.062961 (rank : 303)
Query Neighborhood Hits	345	Target Neighborhood Hits	1551	Shared Neighborhood Hits	130
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PCNT_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.055806 (rank : 372)
Query Neighborhood Hits	345	Target Neighborhood Hits	1207	Shared Neighborhood Hits	125
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PDL1_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.052055 (rank : 424)
Query Neighborhood Hits	345	Target Neighborhood Hits	195	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.067260 (rank : 285)
Query Neighborhood Hits	345	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.056677 (rank : 364)
Query Neighborhood Hits	345	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.053877 (rank : 402)
Query Neighborhood Hits	345	Target Neighborhood Hits	116	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PF21A_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.054623 (rank : 391)
Query Neighborhood Hits	345	Target Neighborhood Hits	303	Shared Neighborhood Hits	33
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.053946 (rank : 400)
Query Neighborhood Hits	345	Target Neighborhood Hits	285	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PIBF1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.054363 (rank : 394)
Query Neighborhood Hits	345	Target Neighborhood Hits	1041	Shared Neighborhood Hits	107
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PJA1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.061519 (rank : 309)
Query Neighborhood Hits	345	Target Neighborhood Hits	159	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.054858 (rank : 388)
Query Neighborhood Hits	345	Target Neighborhood Hits	145	Shared Neighborhood Hits	47
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RAD50_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.051434 (rank : 428)
Query Neighborhood Hits	345	Target Neighborhood Hits	1317	Shared Neighborhood Hits	108
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.051051 (rank : 435)
Query Neighborhood Hits	345	Target Neighborhood Hits	1366	Shared Neighborhood Hits	113
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RB6I2_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.057777 (rank : 348)
Query Neighborhood Hits	345	Target Neighborhood Hits	1584	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.060433 (rank : 319)
Query Neighborhood Hits	345	Target Neighborhood Hits	1433	Shared Neighborhood Hits	126
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBCC1_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.064511 (rank : 297)
Query Neighborhood Hits	345	Target Neighborhood Hits	1023	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBP24_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.065431 (rank : 291)
Query Neighborhood Hits	345	Target Neighborhood Hits	1559	Shared Neighborhood Hits	149
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

REST_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.059547 (rank : 328)
Query Neighborhood Hits	345	Target Neighborhood Hits	1605	Shared Neighborhood Hits	137
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.052302 (rank : 421)
Query Neighborhood Hits	345	Target Neighborhood Hits	1506	Shared Neighborhood Hits	125
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RN122_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.058451 (rank : 340)
Query Neighborhood Hits	345	Target Neighborhood Hits	121	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.053393 (rank : 410)
Query Neighborhood Hits	345	Target Neighborhood Hits	121	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN123_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.076053 (rank : 262)
Query Neighborhood Hits	345	Target Neighborhood Hits	175	Shared Neighborhood Hits	102
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.075555 (rank : 264)
Query Neighborhood Hits	345	Target Neighborhood Hits	174	Shared Neighborhood Hits	103
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN126_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.051317 (rank : 430)
Query Neighborhood Hits	345	Target Neighborhood Hits	143	Shared Neighborhood Hits	61
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN152_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.187141 (rank : 195)
Query Neighborhood Hits	345	Target Neighborhood Hits	107	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.191291 (rank : 193)
Query Neighborhood Hits	345	Target Neighborhood Hits	109	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN165_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.052225 (rank : 422)
Query Neighborhood Hits	345	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN167_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.055300 (rank : 381)
Query Neighborhood Hits	345	Target Neighborhood Hits	157	Shared Neighborhood Hits	64
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF13_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.054867 (rank : 387)
Query Neighborhood Hits	345	Target Neighborhood Hits	164	Shared Neighborhood Hits	56
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF32_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.071282 (rank : 278)
Query Neighborhood Hits	345	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.060461 (rank : 318)
Query Neighborhood Hits	345	Target Neighborhood Hits	129	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF4_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.217752 (rank : 183)
Query Neighborhood Hits	345	Target Neighborhood Hits	212	Shared Neighborhood Hits	137
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.215813 (rank : 186)
Query Neighborhood Hits	345	Target Neighborhood Hits	212	Shared Neighborhood Hits	138
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RSF1_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.051136 (rank : 432)
Query Neighborhood Hits	345	Target Neighborhood Hits	539	Shared Neighborhood Hits	58
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SDCG8_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.059536 (rank : 329)
Query Neighborhood Hits	345	Target Neighborhood Hits	1002	Shared Neighborhood Hits	105
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.058217 (rank : 342)
Query Neighborhood Hits	345	Target Neighborhood Hits	886	Shared Neighborhood Hits	98
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SP110_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.052664 (rank : 418)
Query Neighborhood Hits	345	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SPAG5_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.053576 (rank : 406)
Query Neighborhood Hits	345	Target Neighborhood Hits	612	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SYCP1_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.055704 (rank : 374)
Query Neighborhood Hits	345	Target Neighborhood Hits	1313	Shared Neighborhood Hits	114
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYCP1_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.068715 (rank : 280)
Query Neighborhood Hits	345	Target Neighborhood Hits	1456	Shared Neighborhood Hits	139
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

T3JAM_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.050162 (rank : 446)
Query Neighborhood Hits	345	Target Neighborhood Hits	535	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TMF1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.051767 (rank : 426)
Query Neighborhood Hits	345	Target Neighborhood Hits	987	Shared Neighborhood Hits	105
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TRAF2_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.123943 (rank : 227)
Query Neighborhood Hits	345	Target Neighborhood Hits	402	Shared Neighborhood Hits	125
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.117898 (rank : 237)
Query Neighborhood Hits	345	Target Neighborhood Hits	394	Shared Neighborhood Hits	128
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.118977 (rank : 236)
Query Neighborhood Hits	345	Target Neighborhood Hits	463	Shared Neighborhood Hits	169
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.119917 (rank : 233)
Query Neighborhood Hits	345	Target Neighborhood Hits	476	Shared Neighborhood Hits	179
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.160198 (rank : 211)
Query Neighborhood Hits	345	Target Neighborhood Hits	373	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.088883 (rank : 250)
Query Neighborhood Hits	345	Target Neighborhood Hits	338	Shared Neighborhood Hits	99
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.149525 (rank : 215)
Query Neighborhood Hits	345	Target Neighborhood Hits	396	Shared Neighborhood Hits	159
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.167258 (rank : 204)
Query Neighborhood Hits	345	Target Neighborhood Hits	355	Shared Neighborhood Hits	153
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAIP_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.104736 (rank : 247)
Query Neighborhood Hits	345	Target Neighborhood Hits	780	Shared Neighborhood Hits	147
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.097065 (rank : 248)
Query Neighborhood Hits	345	Target Neighborhood Hits	745	Shared Neighborhood Hits	141
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRHY_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.054682 (rank : 390)
Query Neighborhood Hits	345	Target Neighborhood Hits	1385	Shared Neighborhood Hits	115
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRIPB_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.060047 (rank : 321)
Query Neighborhood Hits	345	Target Neighborhood Hits	1587	Shared Neighborhood Hits	134
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

UACA_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.054290 (rank : 395)
Query Neighborhood Hits	345	Target Neighborhood Hits	1622	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UB7I3_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.073512 (rank : 269)
Query Neighborhood Hits	345	Target Neighborhood Hits	136	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.089868 (rank : 249)
Query Neighborhood Hits	345	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

ZN363_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.053205 (rank : 413)
Query Neighborhood Hits	345	Target Neighborhood Hits	162	Shared Neighborhood Hits	28
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.053221 (rank : 412)
Query Neighborhood Hits	345	Target Neighborhood Hits	134	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN364_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.052446 (rank : 420)
Query Neighborhood Hits	345	Target Neighborhood Hits	140	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.077064 (rank : 260)
Query Neighborhood Hits	345	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.061543 (rank : 308)
Query Neighborhood Hits	345	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

TRIM1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	345	Target Neighborhood Hits	345	Shared Neighborhood Hits	345
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.997071 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	345	Target Neighborhood Hits	361	Shared Neighborhood Hits	336
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI18_MOUSE
NC score	0.981161 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	345	Target Neighborhood Hits	292	Shared Neighborhood Hits	238
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI18_HUMAN
NC score	0.978702 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	345	Target Neighborhood Hits	307	Shared Neighborhood Hits	242
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI36_MOUSE
NC score	0.859031 (rank : 5)	θ value	2.32979e-56 (rank : 5)
Query Neighborhood Hits	345	Target Neighborhood Hits	266	Shared Neighborhood Hits	191
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI36_HUMAN
NC score	0.857573 (rank : 6)	θ value	3.0428e-56 (rank : 6)
Query Neighborhood Hits	345	Target Neighborhood Hits	282	Shared Neighborhood Hits	191
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI46_MOUSE
NC score	0.853788 (rank : 7)	θ value	1.36902e-48 (rank : 8)
Query Neighborhood Hits	345	Target Neighborhood Hits	287	Shared Neighborhood Hits	200
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.853192 (rank : 8)	θ value	9.48078e-50 (rank : 7)
Query Neighborhood Hits	345	Target Neighborhood Hits	291	Shared Neighborhood Hits	200
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM9_HUMAN
NC score	0.819950 (rank : 9)	θ value	4.40402e-47 (rank : 9)
Query Neighborhood Hits	345	Target Neighborhood Hits	294	Shared Neighborhood Hits	189
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
NC score	0.795456 (rank : 10)	θ value	7.52953e-39 (rank : 10)
Query Neighborhood Hits	345	Target Neighborhood Hits	274	Shared Neighborhood Hits	184
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI63_MOUSE
NC score	0.792166 (rank : 11)	θ value	2.96777e-27 (rank : 13)
Query Neighborhood Hits	345	Target Neighborhood Hits	240	Shared Neighborhood Hits	183
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI54_MOUSE
NC score	0.783268 (rank : 12)	θ value	2.51237e-26 (rank : 14)
Query Neighborhood Hits	345	Target Neighborhood Hits	197	Shared Neighborhood Hits	164
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
NC score	0.782755 (rank : 13)	θ value	5.77852e-31 (rank : 12)
Query Neighborhood Hits	345	Target Neighborhood Hits	292	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI63_HUMAN
NC score	0.780888 (rank : 14)	θ value	6.18819e-25 (rank : 16)
Query Neighborhood Hits	345	Target Neighborhood Hits	298	Shared Neighborhood Hits	191
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI54_HUMAN
NC score	0.779409 (rank : 15)	θ value	8.08199e-25 (rank : 17)
Query Neighborhood Hits	345	Target Neighborhood Hits	209	Shared Neighborhood Hits	168
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI25_HUMAN
NC score	0.778141 (rank : 16)	θ value	6.17384e-33 (rank : 11)
Query Neighborhood Hits	345	Target Neighborhood Hits	472	Shared Neighborhood Hits	249
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
NC score	0.755098 (rank : 17)	θ value	1.13037e-18 (rank : 21)
Query Neighborhood Hits	345	Target Neighborhood Hits	446	Shared Neighborhood Hits	238
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRIM8_MOUSE
NC score	0.744722 (rank : 18)	θ value	1.99067e-23 (rank : 18)
Query Neighborhood Hits	345	Target Neighborhood Hits	674	Shared Neighborhood Hits	238
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
NC score	0.741836 (rank : 19)	θ value	9.87957e-23 (rank : 19)
Query Neighborhood Hits	345	Target Neighborhood Hits	650	Shared Neighborhood Hits	239
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI59_MOUSE
NC score	0.722742 (rank : 20)	θ value	3.40345e-15 (rank : 29)
Query Neighborhood Hits	345	Target Neighborhood Hits	292	Shared Neighborhood Hits	201
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.721665 (rank : 21)	θ value	1.99529e-15 (rank : 28)
Query Neighborhood Hits	345	Target Neighborhood Hits	307	Shared Neighborhood Hits	203
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI47_MOUSE
NC score	0.703635 (rank : 22)	θ value	1.42992e-13 (rank : 38)
Query Neighborhood Hits	345	Target Neighborhood Hits	295	Shared Neighborhood Hits	205
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI13_HUMAN
NC score	0.696050 (rank : 23)	θ value	2.20605e-14 (rank : 31)
Query Neighborhood Hits	345	Target Neighborhood Hits	274	Shared Neighborhood Hits	196
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
NC score	0.695171 (rank : 24)	θ value	8.38298e-14 (rank : 35)
Query Neighborhood Hits	345	Target Neighborhood Hits	282	Shared Neighborhood Hits	195
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI42_MOUSE
NC score	0.694803 (rank : 25)	θ value	6.18819e-25 (rank : 15)
Query Neighborhood Hits	345	Target Neighborhood Hits	316	Shared Neighborhood Hits	139
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI47_HUMAN
NC score	0.691072 (rank : 26)	θ value	1.58096e-12 (rank : 42)
Query Neighborhood Hits	345	Target Neighborhood Hits	286	Shared Neighborhood Hits	207
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI42_HUMAN
NC score	0.688429 (rank : 27)	θ value	3.75424e-22 (rank : 20)
Query Neighborhood Hits	345	Target Neighborhood Hits	283	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI14_MOUSE
NC score	0.682318 (rank : 28)	θ value	9.26847e-13 (rank : 41)
Query Neighborhood Hits	345	Target Neighborhood Hits	137	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI14_HUMAN
NC score	0.676557 (rank : 29)	θ value	2.69671e-12 (rank : 44)
Query Neighborhood Hits	345	Target Neighborhood Hits	143	Shared Neighborhood Hits	121
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI50_HUMAN
NC score	0.669653 (rank : 30)	θ value	2.13673e-09 (rank : 71)
Query Neighborhood Hits	345	Target Neighborhood Hits	294	Shared Neighborhood Hits	218
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_MOUSE
NC score	0.669478 (rank : 31)	θ value	6.21693e-09 (rank : 75)
Query Neighborhood Hits	345	Target Neighborhood Hits	326	Shared Neighborhood Hits	226
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI56_MOUSE
NC score	0.660013 (rank : 32)	θ value	2.28291e-11 (rank : 54)
Query Neighborhood Hits	345	Target Neighborhood Hits	255	Shared Neighborhood Hits	174
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI62_MOUSE
NC score	0.659459 (rank : 33)	θ value	3.64472e-09 (rank : 73)
Query Neighborhood Hits	345	Target Neighborhood Hits	478	Shared Neighborhood Hits	241
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_HUMAN
NC score	0.656729 (rank : 34)	θ value	1.06045e-08 (rank : 77)
Query Neighborhood Hits	345	Target Neighborhood Hits	584	Shared Neighborhood Hits	251
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM3_MOUSE
NC score	0.647774 (rank : 35)	θ value	6.00763e-12 (rank : 50)
Query Neighborhood Hits	345	Target Neighborhood Hits	351	Shared Neighborhood Hits	193
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI56_HUMAN
NC score	0.643389 (rank : 36)	θ value	3.29651e-10 (rank : 67)
Query Neighborhood Hits	345	Target Neighborhood Hits	339	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI16_MOUSE
NC score	0.643081 (rank : 37)	θ value	7.09661e-13 (rank : 40)
Query Neighborhood Hits	345	Target Neighborhood Hits	196	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI39_HUMAN
NC score	0.641914 (rank : 38)	θ value	2.98157e-11 (rank : 57)
Query Neighborhood Hits	345	Target Neighborhood Hits	693	Shared Neighborhood Hits	268
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
NC score	0.641380 (rank : 39)	θ value	1.74796e-11 (rank : 52)
Query Neighborhood Hits	345	Target Neighborhood Hits	691	Shared Neighborhood Hits	275
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM3_HUMAN
NC score	0.639600 (rank : 40)	θ value	5.08577e-11 (rank : 60)
Query Neighborhood Hits	345	Target Neighborhood Hits	357	Shared Neighborhood Hits	197
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI65_HUMAN
NC score	0.638770 (rank : 41)	θ value	1.69304e-06 (rank : 99)
Query Neighborhood Hits	345	Target Neighborhood Hits	330	Shared Neighborhood Hits	224
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI41_HUMAN
NC score	0.638437 (rank : 42)	θ value	1.74796e-11 (rank : 53)
Query Neighborhood Hits	345	Target Neighborhood Hits	349	Shared Neighborhood Hits	209
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM2_HUMAN
NC score	0.636649 (rank : 43)	θ value	6.64225e-11 (rank : 61)
Query Neighborhood Hits	345	Target Neighborhood Hits	330	Shared Neighborhood Hits	195
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRI45_MOUSE
NC score	0.634270 (rank : 44)	θ value	1.24977e-17 (rank : 22)
Query Neighborhood Hits	345	Target Neighborhood Hits	155	Shared Neighborhood Hits	115
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRIM2_MOUSE
NC score	0.634074 (rank : 45)	θ value	8.67504e-11 (rank : 63)
Query Neighborhood Hits	345	Target Neighborhood Hits	331	Shared Neighborhood Hits	196
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM4_HUMAN
NC score	0.633343 (rank : 46)	θ value	4.76016e-09 (rank : 74)
Query Neighborhood Hits	345	Target Neighborhood Hits	321	Shared Neighborhood Hits	225
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI60_HUMAN
NC score	0.631852 (rank : 47)	θ value	2.61198e-07 (rank : 89)
Query Neighborhood Hits	345	Target Neighborhood Hits	357	Shared Neighborhood Hits	237
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRIM7_MOUSE
NC score	0.631845 (rank : 48)	θ value	1.53129e-07 (rank : 88)
Query Neighborhood Hits	345	Target Neighborhood Hits	358	Shared Neighborhood Hits	224
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI45_HUMAN
NC score	0.631649 (rank : 49)	θ value	4.02038e-16 (rank : 25)
Query Neighborhood Hits	345	Target Neighborhood Hits	155	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI73_HUMAN
NC score	0.630751 (rank : 50)	θ value	1.29631e-06 (rank : 97)
Query Neighborhood Hits	345	Target Neighborhood Hits	258	Shared Neighborhood Hits	204
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
NC score	0.629694 (rank : 51)	θ value	1.29631e-06 (rank : 98)
Query Neighborhood Hits	345	Target Neighborhood Hits	249	Shared Neighborhood Hits	198
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI27_HUMAN
NC score	0.629572 (rank : 52)	θ value	5.26297e-08 (rank : 83)
Query Neighborhood Hits	345	Target Neighborhood Hits	273	Shared Neighborhood Hits	209
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.627498 (rank : 53)	θ value	5.26297e-08 (rank : 84)
Query Neighborhood Hits	345	Target Neighborhood Hits	261	Shared Neighborhood Hits	200
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI11_HUMAN
NC score	0.627275 (rank : 54)	θ value	3.64472e-09 (rank : 72)
Query Neighborhood Hits	345	Target Neighborhood Hits	316	Shared Neighborhood Hits	216
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
NC score	0.627105 (rank : 55)	θ value	2.52405e-10 (rank : 65)
Query Neighborhood Hits	345	Target Neighborhood Hits	329	Shared Neighborhood Hits	217
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI16_HUMAN
NC score	0.625372 (rank : 56)	θ value	1.74796e-11 (rank : 51)
Query Neighborhood Hits	345	Target Neighborhood Hits	231	Shared Neighborhood Hits	137
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI68_MOUSE
NC score	0.624238 (rank : 57)	θ value	7.34386e-10 (rank : 69)
Query Neighborhood Hits	345	Target Neighborhood Hits	356	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI35_MOUSE
NC score	0.623781 (rank : 58)	θ value	1.80886e-08 (rank : 80)
Query Neighborhood Hits	345	Target Neighborhood Hits	465	Shared Neighborhood Hits	247
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI31_HUMAN
NC score	0.622980 (rank : 59)	θ value	4.0297e-08 (rank : 81)
Query Neighborhood Hits	345	Target Neighborhood Hits	299	Shared Neighborhood Hits	208
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI34_HUMAN
NC score	0.622038 (rank : 60)	θ value	2.52405e-10 (rank : 66)
Query Neighborhood Hits	345	Target Neighborhood Hits	416	Shared Neighborhood Hits	227
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

SPRY4_MOUSE
NC score	0.621460 (rank : 61)	θ value	3.76295e-14 (rank : 33)
Query Neighborhood Hits	345	Target Neighborhood Hits	82	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI17_MOUSE
NC score	0.620653 (rank : 62)	θ value	3.77169e-06 (rank : 105)
Query Neighborhood Hits	345	Target Neighborhood Hits	620	Shared Neighborhood Hits	254
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI22_HUMAN
NC score	0.618689 (rank : 63)	θ value	1.06045e-08 (rank : 76)
Query Neighborhood Hits	345	Target Neighborhood Hits	396	Shared Neighborhood Hits	230
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI15_HUMAN
NC score	0.618405 (rank : 64)	θ value	9.92553e-07 (rank : 92)
Query Neighborhood Hits	345	Target Neighborhood Hits	395	Shared Neighborhood Hits	230
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_HUMAN
NC score	0.617388 (rank : 65)	θ value	4.92598e-06 (rank : 109)
Query Neighborhood Hits	345	Target Neighborhood Hits	318	Shared Neighborhood Hits	213
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI10_MOUSE
NC score	0.616818 (rank : 66)	θ value	1.87187e-05 (rank : 112)
Query Neighborhood Hits	345	Target Neighborhood Hits	285	Shared Neighborhood Hits	214
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRIM7_HUMAN
NC score	0.616666 (rank : 67)	θ value	1.69304e-06 (rank : 100)
Query Neighborhood Hits	345	Target Neighborhood Hits	336	Shared Neighborhood Hits	222
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI35_HUMAN
NC score	0.616434 (rank : 68)	θ value	5.81887e-07 (rank : 91)
Query Neighborhood Hits	345	Target Neighborhood Hits	382	Shared Neighborhood Hits	225
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI60_MOUSE
NC score	0.615981 (rank : 69)	θ value	1.38499e-08 (rank : 78)
Query Neighborhood Hits	345	Target Neighborhood Hits	240	Shared Neighborhood Hits	188
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI68_HUMAN
NC score	0.615844 (rank : 70)	θ value	5.08577e-11 (rank : 59)
Query Neighborhood Hits	345	Target Neighborhood Hits	267	Shared Neighborhood Hits	203
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI65_MOUSE
NC score	0.615010 (rank : 71)	θ value	0.000121331 (rank : 117)
Query Neighborhood Hits	345	Target Neighborhood Hits	340	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI38_HUMAN
NC score	0.613984 (rank : 72)	θ value	8.97725e-08 (rank : 86)
Query Neighborhood Hits	345	Target Neighborhood Hits	373	Shared Neighborhood Hits	223
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI10_HUMAN
NC score	0.613683 (rank : 73)	θ value	0.000602161 (rank : 126)
Query Neighborhood Hits	345	Target Neighborhood Hits	315	Shared Neighborhood Hits	222
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

RO52_HUMAN
NC score	0.613520 (rank : 74)	θ value	1.29631e-06 (rank : 93)
Query Neighborhood Hits	345	Target Neighborhood Hits	419	Shared Neighborhood Hits	246
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRIM5_HUMAN
NC score	0.611230 (rank : 75)	θ value	4.45536e-07 (rank : 90)
Query Neighborhood Hits	345	Target Neighborhood Hits	424	Shared Neighborhood Hits	240
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

RNF39_HUMAN
NC score	0.610926 (rank : 76)	θ value	1.43324e-05 (rank : 111)
Query Neighborhood Hits	345	Target Neighborhood Hits	200	Shared Neighborhood Hits	175
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI26_HUMAN
NC score	0.610755 (rank : 77)	θ value	1.133e-10 (rank : 64)
Query Neighborhood Hits	345	Target Neighborhood Hits	335	Shared Neighborhood Hits	217
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI30_MOUSE
NC score	0.610600 (rank : 78)	θ value	1.29631e-06 (rank : 94)
Query Neighborhood Hits	345	Target Neighborhood Hits	434	Shared Neighborhood Hits	240
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

SPRY4_HUMAN
NC score	0.609759 (rank : 79)	θ value	2.20605e-14 (rank : 30)
Query Neighborhood Hits	345	Target Neighborhood Hits	79	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRIM6_HUMAN
NC score	0.606100 (rank : 80)	θ value	1.38499e-08 (rank : 79)
Query Neighborhood Hits	345	Target Neighborhood Hits	412	Shared Neighborhood Hits	234
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM6_MOUSE
NC score	0.599510 (rank : 81)	θ value	2.21117e-06 (rank : 102)
Query Neighborhood Hits	345	Target Neighborhood Hits	451	Shared Neighborhood Hits	238
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI26_MOUSE
NC score	0.598512 (rank : 82)	θ value	5.26297e-08 (rank : 82)
Query Neighborhood Hits	345	Target Neighborhood Hits	339	Shared Neighborhood Hits	217
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI29_MOUSE
NC score	0.595815 (rank : 83)	θ value	2.98157e-11 (rank : 56)
Query Neighborhood Hits	345	Target Neighborhood Hits	306	Shared Neighborhood Hits	130
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

RO52_MOUSE
NC score	0.592559 (rank : 84)	θ value	4.92598e-06 (rank : 108)
Query Neighborhood Hits	345	Target Neighborhood Hits	360	Shared Neighborhood Hits	227
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI29_HUMAN
NC score	0.591658 (rank : 85)	θ value	2.69671e-12 (rank : 45)
Query Neighborhood Hits	345	Target Neighborhood Hits	273	Shared Neighborhood Hits	120
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI12_MOUSE
NC score	0.588429 (rank : 86)	θ value	1.53129e-07 (rank : 87)
Query Neighborhood Hits	345	Target Neighborhood Hits	387	Shared Neighborhood Hits	208
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI34_MOUSE
NC score	0.582600 (rank : 87)	θ value	1.29631e-06 (rank : 95)
Query Neighborhood Hits	345	Target Neighborhood Hits	332	Shared Neighborhood Hits	201
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI43_HUMAN
NC score	0.582391 (rank : 88)	θ value	2.88788e-06 (rank : 104)
Query Neighborhood Hits	345	Target Neighborhood Hits	341	Shared Neighborhood Hits	220
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

BSPRY_HUMAN
NC score	0.571053 (rank : 89)	θ value	8.67504e-11 (rank : 62)
Query Neighborhood Hits	345	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI52_HUMAN
NC score	0.569093 (rank : 90)	θ value	0.000461057 (rank : 124)
Query Neighborhood Hits	345	Target Neighborhood Hits	213	Shared Neighborhood Hits	173
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI32_MOUSE
NC score	0.567506 (rank : 91)	θ value	7.34386e-10 (rank : 68)
Query Neighborhood Hits	345	Target Neighborhood Hits	271	Shared Neighborhood Hits	176
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI32_HUMAN
NC score	0.567030 (rank : 92)	θ value	1.63604e-09 (rank : 70)
Query Neighborhood Hits	345	Target Neighborhood Hits	264	Shared Neighborhood Hits	170
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

BSPRY_MOUSE
NC score	0.563572 (rank : 93)	θ value	2.98157e-11 (rank : 55)
Query Neighborhood Hits	345	Target Neighborhood Hits	163	Shared Neighborhood Hits	99
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI48_HUMAN
NC score	0.558524 (rank : 94)	θ value	0.000158464 (rank : 119)
Query Neighborhood Hits	345	Target Neighborhood Hits	192	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

MEFV_HUMAN
NC score	0.544410 (rank : 95)	θ value	6.43352e-06 (rank : 110)
Query Neighborhood Hits	345	Target Neighborhood Hits	431	Shared Neighborhood Hits	150
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI49_HUMAN
NC score	0.540626 (rank : 96)	θ value	0.000602161 (rank : 127)
Query Neighborhood Hits	345	Target Neighborhood Hits	199	Shared Neighborhood Hits	177
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI44_MOUSE
NC score	0.516396 (rank : 97)	θ value	1.29631e-06 (rank : 96)
Query Neighborhood Hits	345	Target Neighborhood Hits	327	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TIF1B_HUMAN
NC score	0.515802 (rank : 98)	θ value	1.09485e-13 (rank : 36)
Query Neighborhood Hits	345	Target Neighborhood Hits	312	Shared Neighborhood Hits	115
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI40_HUMAN
NC score	0.513610 (rank : 99)	θ value	0.47712 (rank : 217)
Query Neighborhood Hits	345	Target Neighborhood Hits	279	Shared Neighborhood Hits	184
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TIF1B_MOUSE
NC score	0.511477 (rank : 100)	θ value	1.42992e-13 (rank : 37)
Query Neighborhood Hits	345	Target Neighborhood Hits	276	Shared Neighborhood Hits	110
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

ERMAP_HUMAN
NC score	0.511316 (rank : 101)	θ value	3.52202e-12 (rank : 47)
Query Neighborhood Hits	345	Target Neighborhood Hits	155	Shared Neighborhood Hits	81
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI44_HUMAN
NC score	0.509407 (rank : 102)	θ value	3.77169e-06 (rank : 106)
Query Neighborhood Hits	345	Target Neighborhood Hits	393	Shared Neighborhood Hits	116
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI37_HUMAN
NC score	0.508877 (rank : 103)	θ value	0.000461057 (rank : 122)
Query Neighborhood Hits	345	Target Neighborhood Hits	307	Shared Neighborhood Hits	173
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.508425 (rank : 104)	θ value	0.000461057 (rank : 123)
Query Neighborhood Hits	345	Target Neighborhood Hits	316	Shared Neighborhood Hits	171
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TIF1G_HUMAN
NC score	0.506574 (rank : 105)	θ value	1.52774e-15 (rank : 26)
Query Neighborhood Hits	345	Target Neighborhood Hits	410	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.500507 (rank : 106)	θ value	1.52774e-15 (rank : 27)
Query Neighborhood Hits	345	Target Neighborhood Hits	498	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

RFPL3_HUMAN
NC score	0.495053 (rank : 107)	θ value	7.1131e-05 (rank : 116)
Query Neighborhood Hits	345	Target Neighborhood Hits	134	Shared Neighborhood Hits	122
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

ERMAP_MOUSE
NC score	0.491732 (rank : 108)	θ value	2.0648e-12 (rank : 43)
Query Neighborhood Hits	345	Target Neighborhood Hits	231	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

RFPL1_HUMAN
NC score	0.488410 (rank : 109)	θ value	2.44474e-05 (rank : 113)
Query Neighborhood Hits	345	Target Neighborhood Hits	119	Shared Neighborhood Hits	111
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

BT1A1_MOUSE
NC score	0.486968 (rank : 110)	θ value	3.52202e-12 (rank : 46)
Query Neighborhood Hits	345	Target Neighborhood Hits	252	Shared Neighborhood Hits	87
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_HUMAN
NC score	0.483608 (rank : 111)	θ value	4.59992e-12 (rank : 48)
Query Neighborhood Hits	345	Target Neighborhood Hits	322	Shared Neighborhood Hits	90
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A1_HUMAN
NC score	0.481611 (rank : 112)	θ value	3.76295e-14 (rank : 32)
Query Neighborhood Hits	345	Target Neighborhood Hits	229	Shared Neighborhood Hits	88
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

RFPL2_HUMAN
NC score	0.481094 (rank : 113)	θ value	0.000158464 (rank : 118)
Query Neighborhood Hits	345	Target Neighborhood Hits	126	Shared Neighborhood Hits	114
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

BT3A3_HUMAN
NC score	0.480050 (rank : 114)	θ value	6.00763e-12 (rank : 49)
Query Neighborhood Hits	345	Target Neighborhood Hits	233	Shared Neighborhood Hits	85
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL9_HUMAN
NC score	0.474366 (rank : 115)	θ value	3.89403e-11 (rank : 58)
Query Neighborhood Hits	345	Target Neighborhood Hits	125	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BT2A2_HUMAN
NC score	0.471982 (rank : 116)	θ value	8.97725e-08 (rank : 85)
Query Neighborhood Hits	345	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BTNL3_HUMAN
NC score	0.464378 (rank : 117)	θ value	2.88788e-06 (rank : 103)
Query Neighborhood Hits	345	Target Neighborhood Hits	143	Shared Neighborhood Hits	80
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

ZN313_MOUSE
NC score	0.462434 (rank : 118)	θ value	0.00020696 (rank : 121)
Query Neighborhood Hits	345	Target Neighborhood Hits	273	Shared Neighborhood Hits	175
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

BT2A1_HUMAN
NC score	0.449900 (rank : 119)	θ value	0.00020696 (rank : 120)
Query Neighborhood Hits	345	Target Neighborhood Hits	185	Shared Neighborhood Hits	85
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A3_HUMAN
NC score	0.448612 (rank : 120)	θ value	4.92598e-06 (rank : 107)
Query Neighborhood Hits	345	Target Neighborhood Hits	195	Shared Neighborhood Hits	78
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

ZN313_HUMAN
NC score	0.446421 (rank : 121)	θ value	0.00134147 (rank : 129)
Query Neighborhood Hits	345	Target Neighborhood Hits	264	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

MEFV_MOUSE
NC score	0.443170 (rank : 122)	θ value	0.0148317 (rank : 150)
Query Neighborhood Hits	345	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

PML_MOUSE
NC score	0.439278 (rank : 123)	θ value	2.21117e-06 (rank : 101)
Query Neighborhood Hits	345	Target Neighborhood Hits	246	Shared Neighborhood Hits	134
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

BTNL8_HUMAN
NC score	0.436094 (rank : 124)	θ value	0.00175202 (rank : 130)
Query Neighborhood Hits	345	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

RN168_HUMAN
NC score	0.434453 (rank : 125)	θ value	0.00869519 (rank : 147)
Query Neighborhood Hits	345	Target Neighborhood Hits	370	Shared Neighborhood Hits	179
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ZN179_HUMAN
NC score	0.432614 (rank : 126)	θ value	0.00298849 (rank : 136)
Query Neighborhood Hits	345	Target Neighborhood Hits	178	Shared Neighborhood Hits	135
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TIF1A_HUMAN
NC score	0.429893 (rank : 127)	θ value	6.41864e-14 (rank : 34)
Query Neighborhood Hits	345	Target Neighborhood Hits	327	Shared Neighborhood Hits	110
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

RN168_MOUSE
NC score	0.419078 (rank : 128)	θ value	0.0563607 (rank : 166)
Query Neighborhood Hits	345	Target Neighborhood Hits	440	Shared Neighborhood Hits	191
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

BRCA1_HUMAN
NC score	0.402400 (rank : 129)	θ value	0.00869519 (rank : 145)
Query Neighborhood Hits	345	Target Neighborhood Hits	381	Shared Neighborhood Hits	180
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TIF1A_MOUSE
NC score	0.399483 (rank : 130)	θ value	2.43908e-13 (rank : 39)
Query Neighborhood Hits	345	Target Neighborhood Hits	307	Shared Neighborhood Hits	100
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

BRCA1_MOUSE
NC score	0.398421 (rank : 131)	θ value	0.00228821 (rank : 133)
Query Neighborhood Hits	345	Target Neighborhood Hits	436	Shared Neighborhood Hits	177
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RN166_HUMAN
NC score	0.392841 (rank : 132)	θ value	0.0193708 (rank : 153)
Query Neighborhood Hits	345	Target Neighborhood Hits	240	Shared Neighborhood Hits	156
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

PML_HUMAN
NC score	0.392275 (rank : 133)	θ value	0.21417 (rank : 189)
Query Neighborhood Hits	345	Target Neighborhood Hits	248	Shared Neighborhood Hits	122
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RN166_MOUSE
NC score	0.388217 (rank : 134)	θ value	0.0431538 (rank : 159)
Query Neighborhood Hits	345	Target Neighborhood Hits	248	Shared Neighborhood Hits	163
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF8_MOUSE
NC score	0.374833 (rank : 135)	θ value	0.0148317 (rank : 151)
Query Neighborhood Hits	345	Target Neighborhood Hits	618	Shared Neighborhood Hits	235
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF8_HUMAN
NC score	0.368036 (rank : 136)	θ value	0.0113563 (rank : 149)
Query Neighborhood Hits	345	Target Neighborhood Hits	622	Shared Neighborhood Hits	235
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RING1_HUMAN
NC score	0.359500 (rank : 137)	θ value	0.00509761 (rank : 140)
Query Neighborhood Hits	345	Target Neighborhood Hits	219	Shared Neighborhood Hits	145
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.354011 (rank : 138)	θ value	0.00509761 (rank : 141)
Query Neighborhood Hits	345	Target Neighborhood Hits	220	Shared Neighborhood Hits	145
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

BFAR_HUMAN
NC score	0.351400 (rank : 139)	θ value	0.62314 (rank : 219)
Query Neighborhood Hits	345	Target Neighborhood Hits	222	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RAD18_MOUSE
NC score	0.348510 (rank : 140)	θ value	0.00298849 (rank : 135)
Query Neighborhood Hits	345	Target Neighborhood Hits	230	Shared Neighborhood Hits	124
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

PEX10_HUMAN
NC score	0.348063 (rank : 141)	θ value	0.365318 (rank : 207)
Query Neighborhood Hits	345	Target Neighborhood Hits	255	Shared Neighborhood Hits	151
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN183_HUMAN
NC score	0.345393 (rank : 142)	θ value	0.279714 (rank : 204)
Query Neighborhood Hits	345	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN125_MOUSE
NC score	0.344730 (rank : 143)	θ value	0.365318 (rank : 208)
Query Neighborhood Hits	345	Target Neighborhood Hits	220	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN125_HUMAN
NC score	0.342936 (rank : 144)	θ value	1.38821 (rank : 248)
Query Neighborhood Hits	345	Target Neighborhood Hits	230	Shared Neighborhood Hits	152
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RING2_MOUSE
NC score	0.337760 (rank : 145)	θ value	0.00665767 (rank : 144)
Query Neighborhood Hits	345	Target Neighborhood Hits	199	Shared Neighborhood Hits	140
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.337648 (rank : 146)	θ value	0.00665767 (rank : 143)
Query Neighborhood Hits	345	Target Neighborhood Hits	201	Shared Neighborhood Hits	140
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RAD18_HUMAN
NC score	0.334540 (rank : 147)	θ value	0.000602161 (rank : 125)
Query Neighborhood Hits	345	Target Neighborhood Hits	284	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

BFAR_MOUSE
NC score	0.333195 (rank : 148)	θ value	1.06291 (rank : 232)
Query Neighborhood Hits	345	Target Neighborhood Hits	232	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

CHFR_MOUSE
NC score	0.321553 (rank : 149)	θ value	0.0563607 (rank : 161)
Query Neighborhood Hits	345	Target Neighborhood Hits	264	Shared Neighborhood Hits	152
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RNF41_HUMAN
NC score	0.321205 (rank : 150)	θ value	0.279714 (rank : 205)
Query Neighborhood Hits	345	Target Neighborhood Hits	226	Shared Neighborhood Hits	144
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.318779 (rank : 151)	θ value	0.47712 (rank : 214)
Query Neighborhood Hits	345	Target Neighborhood Hits	224	Shared Neighborhood Hits	144
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

CHFR_HUMAN
NC score	0.318362 (rank : 152)	θ value	0.0961366 (rank : 175)
Query Neighborhood Hits	345	Target Neighborhood Hits	255	Shared Neighborhood Hits	152
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

ARD1_MOUSE
NC score	0.316895 (rank : 153)	θ value	6.20254e-17 (rank : 24)
Query Neighborhood Hits	345	Target Neighborhood Hits	573	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

FSD1L_MOUSE
NC score	0.313833 (rank : 154)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	345	Target Neighborhood Hits	78	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

ARD1_HUMAN
NC score	0.308182 (rank : 155)	θ value	1.63225e-17 (rank : 23)
Query Neighborhood Hits	345	Target Neighborhood Hits	621	Shared Neighborhood Hits	91
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

UHRF2_MOUSE
NC score	0.301207 (rank : 156)	θ value	0.000786445 (rank : 128)
Query Neighborhood Hits	345	Target Neighborhood Hits	275	Shared Neighborhood Hits	151
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

RN183_MOUSE
NC score	0.299918 (rank : 157)	θ value	1.38821 (rank : 249)
Query Neighborhood Hits	345	Target Neighborhood Hits	119	Shared Neighborhood Hits	104
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

UHRF2_HUMAN
NC score	0.298045 (rank : 158)	θ value	0.00390308 (rank : 138)
Query Neighborhood Hits	345	Target Neighborhood Hits	269	Shared Neighborhood Hits	152
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

RN169_HUMAN
NC score	0.281148 (rank : 159)	θ value	0.62314 (rank : 222)
Query Neighborhood Hits	345	Target Neighborhood Hits	203	Shared Neighborhood Hits	114
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RFWD2_MOUSE
NC score	0.273129 (rank : 160)	θ value	4.1701e-05 (rank : 115)
Query Neighborhood Hits	345	Target Neighborhood Hits	535	Shared Neighborhood Hits	175
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.272964 (rank : 161)	θ value	4.1701e-05 (rank : 114)
Query Neighborhood Hits	345	Target Neighborhood Hits	518	Shared Neighborhood Hits	171
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

FSD1L_HUMAN
NC score	0.270750 (rank : 162)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	345	Target Neighborhood Hits	57	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

TRAF6_MOUSE
NC score	0.270475 (rank : 163)	θ value	0.0330416 (rank : 156)
Query Neighborhood Hits	345	Target Neighborhood Hits	255	Shared Neighborhood Hits	167
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

RN185_HUMAN
NC score	0.268106 (rank : 164)	θ value	0.813845 (rank : 228)
Query Neighborhood Hits	345	Target Neighborhood Hits	213	Shared Neighborhood Hits	141
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.267656 (rank : 165)	θ value	0.813845 (rank : 229)
Query Neighborhood Hits	345	Target Neighborhood Hits	211	Shared Neighborhood Hits	141
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRAF6_HUMAN
NC score	0.263273 (rank : 166)	θ value	0.163984 (rank : 183)
Query Neighborhood Hits	345	Target Neighborhood Hits	267	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

RN146_HUMAN
NC score	0.261365 (rank : 167)	θ value	1.81305 (rank : 265)
Query Neighborhood Hits	345	Target Neighborhood Hits	162	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

TRI66_MOUSE
NC score	0.260047 (rank : 168)	θ value	0.21417 (rank : 196)
Query Neighborhood Hits	345	Target Neighborhood Hits	491	Shared Neighborhood Hits	88
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RN146_MOUSE
NC score	0.259621 (rank : 169)	θ value	1.81305 (rank : 266)
Query Neighborhood Hits	345	Target Neighborhood Hits	161	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RAG1_HUMAN
NC score	0.259049 (rank : 170)	θ value	0.47712 (rank : 212)
Query Neighborhood Hits	345	Target Neighborhood Hits	203	Shared Neighborhood Hits	134
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
NC score	0.257757 (rank : 171)	θ value	0.47712 (rank : 213)
Query Neighborhood Hits	345	Target Neighborhood Hits	189	Shared Neighborhood Hits	138
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RNF5_HUMAN
NC score	0.253755 (rank : 172)	θ value	1.06291 (rank : 237)
Query Neighborhood Hits	345	Target Neighborhood Hits	206	Shared Neighborhood Hits	137
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI66_HUMAN
NC score	0.252816 (rank : 173)	θ value	0.21417 (rank : 195)
Query Neighborhood Hits	345	Target Neighborhood Hits	479	Shared Neighborhood Hits	87
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RNF5_MOUSE
NC score	0.252070 (rank : 174)	θ value	1.06291 (rank : 238)
Query Neighborhood Hits	345	Target Neighborhood Hits	206	Shared Neighborhood Hits	136
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

R113B_HUMAN
NC score	0.246958 (rank : 175)	θ value	1.38821 (rank : 247)
Query Neighborhood Hits	345	Target Neighborhood Hits	165	Shared Neighborhood Hits	124
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

UHRF1_HUMAN
NC score	0.245729 (rank : 176)	θ value	0.0961366 (rank : 177)
Query Neighborhood Hits	345	Target Neighborhood Hits	272	Shared Neighborhood Hits	151
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

RN141_MOUSE
NC score	0.244134 (rank : 177)	θ value	1.81305 (rank : 264)
Query Neighborhood Hits	345	Target Neighborhood Hits	200	Shared Neighborhood Hits	134
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.243931 (rank : 178)	θ value	1.81305 (rank : 263)
Query Neighborhood Hits	345	Target Neighborhood Hits	199	Shared Neighborhood Hits	133
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

DTX3_MOUSE
NC score	0.236671 (rank : 179)	θ value	0.62314 (rank : 220)
Query Neighborhood Hits	345	Target Neighborhood Hits	202	Shared Neighborhood Hits	139
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

DTX3_HUMAN
NC score	0.231724 (rank : 180)	θ value	0.47712 (rank : 210)
Query Neighborhood Hits	345	Target Neighborhood Hits	198	Shared Neighborhood Hits	137
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

UHRF1_MOUSE
NC score	0.226431 (rank : 181)	θ value	1.38821 (rank : 253)
Query Neighborhood Hits	345	Target Neighborhood Hits	278	Shared Neighborhood Hits	147
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

LNX2_HUMAN
NC score	0.222117 (rank : 182)	θ value	0.0563607 (rank : 165)
Query Neighborhood Hits	345	Target Neighborhood Hits	389	Shared Neighborhood Hits	155
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RNF4_HUMAN
NC score	0.217752 (rank : 183)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	345	Target Neighborhood Hits	212	Shared Neighborhood Hits	137
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

LNX2_MOUSE
NC score	0.217064 (rank : 184)	θ value	0.163984 (rank : 182)
Query Neighborhood Hits	345	Target Neighborhood Hits	407	Shared Neighborhood Hits	154
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX1_MOUSE
NC score	0.216800 (rank : 185)	θ value	0.00665767 (rank : 142)
Query Neighborhood Hits	345	Target Neighborhood Hits	377	Shared Neighborhood Hits	146
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RNF4_MOUSE
NC score	0.215813 (rank : 186)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	345	Target Neighborhood Hits	212	Shared Neighborhood Hits	138
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

LNX1_HUMAN
NC score	0.215775 (rank : 187)	θ value	0.00869519 (rank : 146)
Query Neighborhood Hits	345	Target Neighborhood Hits	379	Shared Neighborhood Hits	153
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

R113A_HUMAN
NC score	0.212870 (rank : 188)	θ value	2.36792 (rank : 280)
Query Neighborhood Hits	345	Target Neighborhood Hits	177	Shared Neighborhood Hits	120
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

BIRC7_HUMAN
NC score	0.212629 (rank : 189)	θ value	0.365318 (rank : 206)
Query Neighborhood Hits	345	Target Neighborhood Hits	185	Shared Neighborhood Hits	137
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

RC3H1_MOUSE
NC score	0.206165 (rank : 190)	θ value	0.21417 (rank : 194)
Query Neighborhood Hits	345	Target Neighborhood Hits	244	Shared Neighborhood Hits	123
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

SMRA3_HUMAN
NC score	0.202220 (rank : 191)	θ value	2.36792 (rank : 285)
Query Neighborhood Hits	345	Target Neighborhood Hits	265	Shared Neighborhood Hits	165
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

RC3H1_HUMAN
NC score	0.197969 (rank : 192)	θ value	0.21417 (rank : 193)
Query Neighborhood Hits	345	Target Neighborhood Hits	433	Shared Neighborhood Hits	129
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RN152_MOUSE
NC score	0.191291 (rank : 193)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	345	Target Neighborhood Hits	109	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

SMRA3_MOUSE
NC score	0.190500 (rank : 194)	θ value	1.81305 (rank : 267)
Query Neighborhood Hits	345	Target Neighborhood Hits	267	Shared Neighborhood Hits	156
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RN152_HUMAN
NC score	0.187141 (rank : 195)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	345	Target Neighborhood Hits	107	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

TOPRS_MOUSE
NC score	0.184912 (rank : 196)	θ value	0.47712 (rank : 216)
Query Neighborhood Hits	345	Target Neighborhood Hits	263	Shared Neighborhood Hits	114
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

PZRN3_MOUSE
NC score	0.184125 (rank : 197)	θ value	0.0736092 (rank : 172)
Query Neighborhood Hits	345	Target Neighborhood Hits	447	Shared Neighborhood Hits	161
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
NC score	0.183711 (rank : 198)	θ value	0.0431538 (rank : 158)
Query Neighborhood Hits	345	Target Neighborhood Hits	438	Shared Neighborhood Hits	169
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PZRN3_HUMAN
NC score	0.183565 (rank : 199)	θ value	0.0736092 (rank : 171)
Query Neighborhood Hits	345	Target Neighborhood Hits	461	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TOPRS_HUMAN
NC score	0.180120 (rank : 200)	θ value	0.47712 (rank : 215)
Query Neighborhood Hits	345	Target Neighborhood Hits	286	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

NHLC1_MOUSE
NC score	0.175767 (rank : 201)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	345	Target Neighborhood Hits	103	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

MNAB_HUMAN
NC score	0.174978 (rank : 202)	θ value	0.279714 (rank : 199)
Query Neighborhood Hits	345	Target Neighborhood Hits	196	Shared Neighborhood Hits	99
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
NC score	0.173351 (rank : 203)	θ value	0.279714 (rank : 200)
Query Neighborhood Hits	345	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

TRAF5_MOUSE
NC score	0.167258 (rank : 204)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	345	Target Neighborhood Hits	355	Shared Neighborhood Hits	153
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

RBBP6_MOUSE
NC score	0.166607 (rank : 205)	θ value	0.21417 (rank : 191)
Query Neighborhood Hits	345	Target Neighborhood Hits	1014	Shared Neighborhood Hits	148
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

PCGF6_MOUSE
NC score	0.164071 (rank : 206)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	345	Target Neighborhood Hits	163	Shared Neighborhood Hits	112
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

CM007_MOUSE
NC score	0.163058 (rank : 207)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	345	Target Neighborhood Hits	416	Shared Neighborhood Hits	155
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TRAF7_MOUSE
NC score	0.161614 (rank : 208)	θ value	0.163984 (rank : 185)
Query Neighborhood Hits	345	Target Neighborhood Hits	470	Shared Neighborhood Hits	152
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.161248 (rank : 209)	θ value	0.163984 (rank : 184)
Query Neighborhood Hits	345	Target Neighborhood Hits	482	Shared Neighborhood Hits	153
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

PCGF6_HUMAN
NC score	0.160831 (rank : 210)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	345	Target Neighborhood Hits	178	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRAF4_HUMAN
NC score	0.160198 (rank : 211)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	345	Target Neighborhood Hits	373	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

NHLC1_HUMAN
NC score	0.157303 (rank : 212)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	345	Target Neighborhood Hits	91	Shared Neighborhood Hits	66
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

BT3A2_HUMAN
NC score	0.152291 (rank : 213)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	345	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

RBBP6_HUMAN
NC score	0.151430 (rank : 214)	θ value	0.21417 (rank : 190)
Query Neighborhood Hits	345	Target Neighborhood Hits	1135	Shared Neighborhood Hits	151
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRAF5_HUMAN
NC score	0.149525 (rank : 215)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	345	Target Neighborhood Hits	396	Shared Neighborhood Hits	159
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

CM007_HUMAN
NC score	0.146792 (rank : 216)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	345	Target Neighborhood Hits	422	Shared Neighborhood Hits	161
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

BTNL1_MOUSE
NC score	0.144588 (rank : 217)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	345	Target Neighborhood Hits	151	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

BTNL2_HUMAN
NC score	0.139247 (rank : 218)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	345	Target Neighborhood Hits	164	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

MGRN1_MOUSE
NC score	0.139178 (rank : 219)	θ value	0.21417 (rank : 188)
Query Neighborhood Hits	345	Target Neighborhood Hits	149	Shared Neighborhood Hits	86
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MGRN1_HUMAN
NC score	0.135306 (rank : 220)	θ value	0.279714 (rank : 198)
Query Neighborhood Hits	345	Target Neighborhood Hits	192	Shared Neighborhood Hits	87
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MOG_HUMAN
NC score	0.134650 (rank : 221)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	345	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_MOUSE
NC score	0.133789 (rank : 222)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	345	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

DTX3L_HUMAN
NC score	0.130560 (rank : 223)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	345	Target Neighborhood Hits	187	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

PCGF2_HUMAN
NC score	0.126941 (rank : 224)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	345	Target Neighborhood Hits	222	Shared Neighborhood Hits	103
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF4_MOUSE
NC score	0.126875 (rank : 225)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	345	Target Neighborhood Hits	163	Shared Neighborhood Hits	102
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.126531 (rank : 226)	θ value	6.88961 (rank : 320)
Query Neighborhood Hits	345	Target Neighborhood Hits	161	Shared Neighborhood Hits	103
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

TRAF2_HUMAN
NC score	0.123943 (rank : 227)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	345	Target Neighborhood Hits	402	Shared Neighborhood Hits	125
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

RKHD1_HUMAN
NC score	0.123784 (rank : 228)	θ value	1.81305 (rank : 262)
Query Neighborhood Hits	345	Target Neighborhood Hits	163	Shared Neighborhood Hits	67
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

PCGF2_MOUSE
NC score	0.123764 (rank : 229)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	345	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

RNF26_HUMAN
NC score	0.122233 (rank : 230)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	345	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

BRE1B_MOUSE
NC score	0.122213 (rank : 231)	θ value	1.38821 (rank : 242)
Query Neighborhood Hits	345	Target Neighborhood Hits	970	Shared Neighborhood Hits	204
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

AMFR2_HUMAN
NC score	0.120605 (rank : 232)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	345	Target Neighborhood Hits	219	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

TRAF3_MOUSE
NC score	0.119917 (rank : 233)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	345	Target Neighborhood Hits	476	Shared Neighborhood Hits	179
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

AMFR_MOUSE
NC score	0.119590 (rank : 234)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	345	Target Neighborhood Hits	208	Shared Neighborhood Hits	108
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

BRE1B_HUMAN
NC score	0.119400 (rank : 235)	θ value	1.38821 (rank : 241)
Query Neighborhood Hits	345	Target Neighborhood Hits	1040	Shared Neighborhood Hits	205
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

TRAF3_HUMAN
NC score	0.118977 (rank : 236)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	345	Target Neighborhood Hits	463	Shared Neighborhood Hits	169
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF2_MOUSE
NC score	0.117898 (rank : 237)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	345	Target Neighborhood Hits	394	Shared Neighborhood Hits	128
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

CBL_HUMAN
NC score	0.110227 (rank : 238)	θ value	8.99809 (rank : 329)
Query Neighborhood Hits	345	Target Neighborhood Hits	353	Shared Neighborhood Hits	131
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBLC_MOUSE
NC score	0.109004 (rank : 239)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	345	Target Neighborhood Hits	186	Shared Neighborhood Hits	113
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBLB_MOUSE
NC score	0.108448 (rank : 240)	θ value	6.88961 (rank : 311)
Query Neighborhood Hits	345	Target Neighborhood Hits	277	Shared Neighborhood Hits	129
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

BIRC8_HUMAN
NC score	0.108300 (rank : 241)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	345	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CBL_MOUSE
NC score	0.108238 (rank : 242)	θ value	8.99809 (rank : 330)
Query Neighborhood Hits	345	Target Neighborhood Hits	426	Shared Neighborhood Hits	136
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBLB_HUMAN
NC score	0.108153 (rank : 243)	θ value	6.88961 (rank : 310)
Query Neighborhood Hits	345	Target Neighborhood Hits	261	Shared Neighborhood Hits	129
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLC_HUMAN
NC score	0.106165 (rank : 244)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	345	Target Neighborhood Hits	173	Shared Neighborhood Hits	108
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

BRE1A_HUMAN
NC score	0.106141 (rank : 245)	θ value	1.81305 (rank : 254)
Query Neighborhood Hits	345	Target Neighborhood Hits	1071	Shared Neighborhood Hits	202
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
NC score	0.105681 (rank : 246)	θ value	1.81305 (rank : 255)
Query Neighborhood Hits	345	Target Neighborhood Hits	1025	Shared Neighborhood Hits	198
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

TRAIP_HUMAN
NC score	0.104736 (rank : 247)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	345	Target Neighborhood Hits	780	Shared Neighborhood Hits	147
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
NC score	0.097065 (rank : 248)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	345	Target Neighborhood Hits	745	Shared Neighborhood Hits	141
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

UB7I3_MOUSE
NC score	0.089868 (rank : 249)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	345	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

TRAF4_MOUSE
NC score	0.088883 (rank : 250)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	345	Target Neighborhood Hits	338	Shared Neighborhood Hits	99
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

PLVAP_HUMAN
NC score	0.083408 (rank : 251)	θ value	0.0330416 (rank : 155)
Query Neighborhood Hits	345	Target Neighborhood Hits	397	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

GOGB1_HUMAN
NC score	0.082384 (rank : 252)	θ value	0.0563607 (rank : 164)
Query Neighborhood Hits	345	Target Neighborhood Hits	2297	Shared Neighborhood Hits	174
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

BARD1_HUMAN
NC score	0.081852 (rank : 253)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	345	Target Neighborhood Hits	427	Shared Neighborhood Hits	92
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CD276_MOUSE
NC score	0.081784 (rank : 254)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	345	Target Neighborhood Hits	243	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

RNF34_MOUSE
NC score	0.080051 (rank : 255)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	345	Target Neighborhood Hits	160	Shared Neighborhood Hits	81
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

CENPF_HUMAN
NC score	0.078773 (rank : 256)	θ value	0.279714 (rank : 197)
Query Neighborhood Hits	345	Target Neighborhood Hits	1932	Shared Neighborhood Hits	157
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

RNF34_HUMAN
NC score	0.078634 (rank : 257)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	345	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

IFT74_HUMAN
NC score	0.077820 (rank : 258)	θ value	0.00298849 (rank : 134)
Query Neighborhood Hits	345	Target Neighborhood Hits	949	Shared Neighborhood Hits	104
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

BARD1_MOUSE
NC score	0.077329 (rank : 259)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	345	Target Neighborhood Hits	411	Shared Neighborhood Hits	90
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ZSWM2_HUMAN
NC score	0.077064 (rank : 260)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	345	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

AKAP9_HUMAN
NC score	0.076669 (rank : 261)	θ value	0.0961366 (rank : 174)
Query Neighborhood Hits	345	Target Neighborhood Hits	1710	Shared Neighborhood Hits	130
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

RN123_HUMAN
NC score	0.076053 (rank : 262)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	345	Target Neighborhood Hits	175	Shared Neighborhood Hits	102
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

CD276_HUMAN
NC score	0.075897 (rank : 263)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	345	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

RN123_MOUSE
NC score	0.075555 (rank : 264)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	345	Target Neighborhood Hits	174	Shared Neighborhood Hits	103
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

CE290_HUMAN
NC score	0.075217 (rank : 265)	θ value	1.81305 (rank : 256)
Query Neighborhood Hits	345	Target Neighborhood Hits	1553	Shared Neighborhood Hits	142
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

GOGA4_HUMAN
NC score	0.074861 (rank : 266)	θ value	0.0563607 (rank : 163)
Query Neighborhood Hits	345	Target Neighborhood Hits	2034	Shared Neighborhood Hits	159
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CCD46_HUMAN
NC score	0.074066 (rank : 267)	θ value	0.813845 (rank : 223)
Query Neighborhood Hits	345	Target Neighborhood Hits	1430	Shared Neighborhood Hits	146
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

BRAP_HUMAN
NC score	0.073887 (rank : 268)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	345	Target Neighborhood Hits	560	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

UB7I3_HUMAN
NC score	0.073512 (rank : 269)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	345	Target Neighborhood Hits	136	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RBCC1_MOUSE
NC score	0.073464 (rank : 270)	θ value	0.21417 (rank : 192)
Query Neighborhood Hits	345	Target Neighborhood Hits	1048	Shared Neighborhood Hits	112
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

CF060_HUMAN
NC score	0.073409 (rank : 271)	θ value	0.21417 (rank : 186)
Query Neighborhood Hits	345	Target Neighborhood Hits	1270	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

EEA1_HUMAN
NC score	0.073342 (rank : 272)	θ value	0.0193708 (rank : 152)
Query Neighborhood Hits	345	Target Neighborhood Hits	1796	Shared Neighborhood Hits	153
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

NIN_HUMAN
NC score	0.073281 (rank : 273)	θ value	0.0330416 (rank : 154)
Query Neighborhood Hits	345	Target Neighborhood Hits	1416	Shared Neighborhood Hits	126
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

GOGA4_MOUSE
NC score	0.073078 (rank : 274)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	345	Target Neighborhood Hits	1939	Shared Neighborhood Hits	157
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LY10_HUMAN
NC score	0.072662 (rank : 275)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	345	Target Neighborhood Hits	151	Shared Neighborhood Hits	15
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

RABE1_HUMAN
NC score	0.071712 (rank : 276)	θ value	0.125558 (rank : 179)
Query Neighborhood Hits	345	Target Neighborhood Hits	1104	Shared Neighborhood Hits	114
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
NC score	0.071315 (rank : 277)	θ value	0.125558 (rank : 180)
Query Neighborhood Hits	345	Target Neighborhood Hits	1105	Shared Neighborhood Hits	116
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RNF32_HUMAN
NC score	0.071282 (rank : 278)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	345	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

ICOSL_HUMAN
NC score	0.068864 (rank : 279)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	345	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

SYCP1_MOUSE
NC score	0.068715 (rank : 280)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	345	Target Neighborhood Hits	1456	Shared Neighborhood Hits	139
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

EEA1_MOUSE
NC score	0.068703 (rank : 281)	θ value	0.0563607 (rank : 162)
Query Neighborhood Hits	345	Target Neighborhood Hits	1637	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MYH11_HUMAN
NC score	0.068371 (rank : 282)	θ value	0.279714 (rank : 201)
Query Neighborhood Hits	345	Target Neighborhood Hits	1806	Shared Neighborhood Hits	147
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CCD41_MOUSE
NC score	0.067762 (rank : 283)	θ value	0.47712 (rank : 209)
Query Neighborhood Hits	345	Target Neighborhood Hits	1399	Shared Neighborhood Hits	128
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MAT1_MOUSE
NC score	0.067666 (rank : 284)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	345	Target Neighborhood Hits	217	Shared Neighborhood Hits	71
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

PDL1_MOUSE
NC score	0.067260 (rank : 285)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	345	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

CP250_HUMAN
NC score	0.066929 (rank : 286)	θ value	2.36792 (rank : 272)
Query Neighborhood Hits	345	Target Neighborhood Hits	1805	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MYH9_HUMAN
NC score	0.066702 (rank : 287)	θ value	0.00390308 (rank : 137)
Query Neighborhood Hits	345	Target Neighborhood Hits	1762	Shared Neighborhood Hits	146
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
NC score	0.066652 (rank : 288)	θ value	0.00509761 (rank : 139)
Query Neighborhood Hits	345	Target Neighborhood Hits	1829	Shared Neighborhood Hits	148
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MAT1_HUMAN
NC score	0.066463 (rank : 289)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	345	Target Neighborhood Hits	179	Shared Neighborhood Hits	64
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MYH11_MOUSE
NC score	0.065527 (rank : 290)	θ value	0.279714 (rank : 202)
Query Neighborhood Hits	345	Target Neighborhood Hits	1777	Shared Neighborhood Hits	142
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RBP24_HUMAN
NC score	0.065431 (rank : 291)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	345	Target Neighborhood Hits	1559	Shared Neighborhood Hits	149
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

BIRC2_HUMAN
NC score	0.065199 (rank : 292)	θ value	5.27518 (rank : 297)
Query Neighborhood Hits	345	Target Neighborhood Hits	142	Shared Neighborhood Hits	85
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

GCC2_HUMAN
NC score	0.065136 (rank : 293)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	345	Target Neighborhood Hits	1558	Shared Neighborhood Hits	149
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

BRAP_MOUSE
NC score	0.064909 (rank : 294)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	345	Target Neighborhood Hits	409	Shared Neighborhood Hits	100
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

GOGA3_MOUSE
NC score	0.064873 (rank : 295)	θ value	0.62314 (rank : 221)
Query Neighborhood Hits	345	Target Neighborhood Hits	1437	Shared Neighborhood Hits	133
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

SIAH2_HUMAN
NC score	0.064658 (rank : 296)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	345	Target Neighborhood Hits	94	Shared Neighborhood Hits	48
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

RBCC1_HUMAN
NC score	0.064511 (rank : 297)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	345	Target Neighborhood Hits	1023	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CP250_MOUSE
NC score	0.064368 (rank : 298)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	345	Target Neighborhood Hits	1583	Shared Neighborhood Hits	138
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MYH10_HUMAN
NC score	0.064331 (rank : 299)	θ value	1.81305 (rank : 260)
Query Neighborhood Hits	345	Target Neighborhood Hits	1620	Shared Neighborhood Hits	142
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

GCC2_MOUSE
NC score	0.064061 (rank : 300)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	345	Target Neighborhood Hits	1619	Shared Neighborhood Hits	147
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MYH10_MOUSE
NC score	0.063750 (rank : 301)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	345	Target Neighborhood Hits	1612	Shared Neighborhood Hits	140
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

IFT74_MOUSE
NC score	0.063145 (rank : 302)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	345	Target Neighborhood Hits	939	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

PCNT_HUMAN
NC score	0.062961 (rank : 303)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	345	Target Neighborhood Hits	1551	Shared Neighborhood Hits	130
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

SIAH2_MOUSE
NC score	0.062890 (rank : 304)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	345	Target Neighborhood Hits	101	Shared Neighborhood Hits	47
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

BAZ2B_HUMAN
NC score	0.062632 (rank : 305)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	345	Target Neighborhood Hits	803	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

TPR_HUMAN
NC score	0.062514 (rank : 306)	θ value	0.813845 (rank : 230)
Query Neighborhood Hits	345	Target Neighborhood Hits	1921	Shared Neighborhood Hits	145
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CD86_HUMAN
NC score	0.061701 (rank : 307)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	345	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

ZSWM2_MOUSE
NC score	0.061543 (rank : 308)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	345	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

PJA1_HUMAN
NC score	0.061519 (rank : 309)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	345	Target Neighborhood Hits	159	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

DZIP3_MOUSE
NC score	0.061353 (rank : 310)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	345	Target Neighborhood Hits	414	Shared Neighborhood Hits	109
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DZIP3_HUMAN
NC score	0.061285 (rank : 311)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	345	Target Neighborhood Hits	399	Shared Neighborhood Hits	105
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

CING_HUMAN
NC score	0.061185 (rank : 312)	θ value	1.81305 (rank : 257)
Query Neighborhood Hits	345	Target Neighborhood Hits	1275	Shared Neighborhood Hits	111
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CYTSA_HUMAN
NC score	0.061118 (rank : 313)	θ value	0.813845 (rank : 225)
Query Neighborhood Hits	345	Target Neighborhood Hits	1138	Shared Neighborhood Hits	115
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CENPE_HUMAN
NC score	0.060945 (rank : 314)	θ value	6.88961 (rank : 312)
Query Neighborhood Hits	345	Target Neighborhood Hits	2060	Shared Neighborhood Hits	156
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

HHLA2_HUMAN
NC score	0.060773 (rank : 315)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	345	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

AIRE_HUMAN
NC score	0.060655 (rank : 316)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	345	Target Neighborhood Hits	144	Shared Neighborhood Hits	14
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

CCD46_MOUSE
NC score	0.060468 (rank : 317)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	345	Target Neighborhood Hits	1405	Shared Neighborhood Hits	135
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

RNF32_MOUSE
NC score	0.060461 (rank : 318)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	345	Target Neighborhood Hits	129	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RB6I2_MOUSE
NC score	0.060433 (rank : 319)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	345	Target Neighborhood Hits	1433	Shared Neighborhood Hits	126
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

GCC1_HUMAN
NC score	0.060161 (rank : 320)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	345	Target Neighborhood Hits	887	Shared Neighborhood Hits	105
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

TRIPB_HUMAN
NC score	0.060047 (rank : 321)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	345	Target Neighborhood Hits	1587	Shared Neighborhood Hits	134
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

MYH7_HUMAN
NC score	0.060030 (rank : 322)	θ value	0.0113563 (rank : 148)
Query Neighborhood Hits	345	Target Neighborhood Hits	1559	Shared Neighborhood Hits	123
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH8_HUMAN
NC score	0.059859 (rank : 323)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	345	Target Neighborhood Hits	1610	Shared Neighborhood Hits	131
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

AIRE_MOUSE
NC score	0.059778 (rank : 324)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	345	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

NUMA1_HUMAN
NC score	0.059708 (rank : 325)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	345	Target Neighborhood Hits	1523	Shared Neighborhood Hits	131
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CING_MOUSE
NC score	0.059620 (rank : 326)	θ value	0.813845 (rank : 224)
Query Neighborhood Hits	345	Target Neighborhood Hits	1432	Shared Neighborhood Hits	117
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

NIN_MOUSE
NC score	0.059588 (rank : 327)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	345	Target Neighborhood Hits	1376	Shared Neighborhood Hits	121
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

REST_HUMAN
NC score	0.059547 (rank : 328)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	345	Target Neighborhood Hits	1605	Shared Neighborhood Hits	137
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SDCG8_HUMAN
NC score	0.059536 (rank : 329)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	345	Target Neighborhood Hits	1002	Shared Neighborhood Hits	105
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

TXLNA_MOUSE
NC score	0.059314 (rank : 330)	θ value	0.0563607 (rank : 168)
Query Neighborhood Hits	345	Target Neighborhood Hits	846	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

HMMR_MOUSE
NC score	0.059200 (rank : 331)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	345	Target Neighborhood Hits	1178	Shared Neighborhood Hits	120
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

ANR26_HUMAN
NC score	0.058889 (rank : 332)	θ value	0.0736092 (rank : 169)
Query Neighborhood Hits	345	Target Neighborhood Hits	1614	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CP135_MOUSE
NC score	0.058838 (rank : 333)	θ value	2.36792 (rank : 271)
Query Neighborhood Hits	345	Target Neighborhood Hits	1278	Shared Neighborhood Hits	114
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CYTSA_MOUSE
NC score	0.058747 (rank : 334)	θ value	1.38821 (rank : 243)
Query Neighborhood Hits	345	Target Neighborhood Hits	1104	Shared Neighborhood Hits	113
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

KTN1_MOUSE
NC score	0.058727 (rank : 335)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	345	Target Neighborhood Hits	1324	Shared Neighborhood Hits	127
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

CNOT4_HUMAN
NC score	0.058692 (rank : 336)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	345	Target Neighborhood Hits	207	Shared Neighborhood Hits	38
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

GOGA2_MOUSE
NC score	0.058683 (rank : 337)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	345	Target Neighborhood Hits	944	Shared Neighborhood Hits	105
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

ABTAP_HUMAN
NC score	0.058633 (rank : 338)	θ value	0.125558 (rank : 178)
Query Neighborhood Hits	345	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CEP63_HUMAN
NC score	0.058614 (rank : 339)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	345	Target Neighborhood Hits	1005	Shared Neighborhood Hits	112
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

RN122_HUMAN
NC score	0.058451 (rank : 340)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	345	Target Neighborhood Hits	121	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

BIRC3_HUMAN
NC score	0.058312 (rank : 341)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	345	Target Neighborhood Hits	133	Shared Neighborhood Hits	77
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

SDCG8_MOUSE
NC score	0.058217 (rank : 342)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	345	Target Neighborhood Hits	886	Shared Neighborhood Hits	98
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

MYH4_HUMAN
NC score	0.058193 (rank : 343)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	345	Target Neighborhood Hits	1377	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH1_HUMAN
NC score	0.057943 (rank : 344)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	345	Target Neighborhood Hits	1478	Shared Neighborhood Hits	126
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

BAZ1A_HUMAN
NC score	0.057899 (rank : 345)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	345	Target Neighborhood Hits	693	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

KTN1_HUMAN
NC score	0.057880 (rank : 346)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	345	Target Neighborhood Hits	1197	Shared Neighborhood Hits	117
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MYH14_MOUSE
NC score	0.057790 (rank : 347)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	345	Target Neighborhood Hits	1225	Shared Neighborhood Hits	116
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

RB6I2_HUMAN
NC score	0.057777 (rank : 348)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	345	Target Neighborhood Hits	1584	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CCD11_HUMAN
NC score	0.057606 (rank : 349)	θ value	8.99809 (rank : 331)
Query Neighborhood Hits	345	Target Neighborhood Hits	822	Shared Neighborhood Hits	100
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

MYOM2_HUMAN
NC score	0.057584 (rank : 350)	θ value	0.0736092 (rank : 170)
Query Neighborhood Hits	345	Target Neighborhood Hits	341	Shared Neighborhood Hits	25
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

CP135_HUMAN
NC score	0.057493 (rank : 351)	θ value	1.06291 (rank : 233)
Query Neighborhood Hits	345	Target Neighborhood Hits	1290	Shared Neighborhood Hits	112
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYH3_HUMAN
NC score	0.057462 (rank : 352)	θ value	1.38821 (rank : 246)
Query Neighborhood Hits	345	Target Neighborhood Hits	1660	Shared Neighborhood Hits	134
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

OFD1_HUMAN
NC score	0.057292 (rank : 353)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	345	Target Neighborhood Hits	753	Shared Neighborhood Hits	86
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

MYH6_HUMAN
NC score	0.057146 (rank : 354)	θ value	0.0961366 (rank : 176)
Query Neighborhood Hits	345	Target Neighborhood Hits	1426	Shared Neighborhood Hits	117
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH13_HUMAN
NC score	0.057104 (rank : 355)	θ value	1.81305 (rank : 261)
Query Neighborhood Hits	345	Target Neighborhood Hits	1504	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

CCD41_HUMAN
NC score	0.057061 (rank : 356)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	345	Target Neighborhood Hits	1139	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

MYH8_MOUSE
NC score	0.056992 (rank : 357)	θ value	8.99809 (rank : 335)
Query Neighborhood Hits	345	Target Neighborhood Hits	1600	Shared Neighborhood Hits	136
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MIB1_HUMAN
NC score	0.056958 (rank : 358)	θ value	2.36792 (rank : 275)
Query Neighborhood Hits	345	Target Neighborhood Hits	470	Shared Neighborhood Hits	100
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

SYNE1_HUMAN
NC score	0.056929 (rank : 359)	θ value	1.38821 (rank : 251)
Query Neighborhood Hits	345	Target Neighborhood Hits	1484	Shared Neighborhood Hits	124
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

FLIP1_MOUSE
NC score	0.056893 (rank : 360)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	345	Target Neighborhood Hits	1176	Shared Neighborhood Hits	112
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MYH1_MOUSE
NC score	0.056844 (rank : 361)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	345	Target Neighborhood Hits	1461	Shared Neighborhood Hits	124
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MIB1_MOUSE
NC score	0.056816 (rank : 362)	θ value	2.36792 (rank : 276)
Query Neighborhood Hits	345	Target Neighborhood Hits	471	Shared Neighborhood Hits	101
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

GOGA3_HUMAN
NC score	0.056789 (rank : 363)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	345	Target Neighborhood Hits	1317	Shared Neighborhood Hits	120
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

PDL2_HUMAN
NC score	0.056677 (rank : 364)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	345	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

MYH6_MOUSE
NC score	0.056387 (rank : 365)	θ value	1.06291 (rank : 236)
Query Neighborhood Hits	345	Target Neighborhood Hits	1501	Shared Neighborhood Hits	129
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH2_HUMAN
NC score	0.056253 (rank : 366)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	345	Target Neighborhood Hits	1491	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH4_MOUSE
NC score	0.056218 (rank : 367)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	345	Target Neighborhood Hits	1476	Shared Neighborhood Hits	129
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

AZI1_MOUSE
NC score	0.056072 (rank : 368)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	345	Target Neighborhood Hits	990	Shared Neighborhood Hits	106
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

ICOSL_MOUSE
NC score	0.055919 (rank : 369)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	345	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

AZI1_HUMAN
NC score	0.055906 (rank : 370)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	345	Target Neighborhood Hits	1000	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

MYO5C_HUMAN
NC score	0.055833 (rank : 371)	θ value	0.279714 (rank : 203)
Query Neighborhood Hits	345	Target Neighborhood Hits	1206	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PCNT_MOUSE
NC score	0.055806 (rank : 372)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	345	Target Neighborhood Hits	1207	Shared Neighborhood Hits	125
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

CROCC_HUMAN
NC score	0.055756 (rank : 373)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	345	Target Neighborhood Hits	1409	Shared Neighborhood Hits	125
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SYCP1_HUMAN
NC score	0.055704 (rank : 374)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	345	Target Neighborhood Hits	1313	Shared Neighborhood Hits	114
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CD86_MOUSE
NC score	0.055674 (rank : 375)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	345	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

HOOK1_HUMAN
NC score	0.055459 (rank : 376)	θ value	2.36792 (rank : 274)
Query Neighborhood Hits	345	Target Neighborhood Hits	942	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

TXLNA_HUMAN
NC score	0.055433 (rank : 377)	θ value	0.0563607 (rank : 167)
Query Neighborhood Hits	345	Target Neighborhood Hits	982	Shared Neighborhood Hits	81
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

CNOT4_MOUSE
NC score	0.055421 (rank : 378)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	345	Target Neighborhood Hits	277	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

FLIP1_HUMAN
NC score	0.055400 (rank : 379)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	345	Target Neighborhood Hits	1405	Shared Neighborhood Hits	127
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CCD11_MOUSE
NC score	0.055315 (rank : 380)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	345	Target Neighborhood Hits	498	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

RN167_MOUSE
NC score	0.055300 (rank : 381)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	345	Target Neighborhood Hits	157	Shared Neighborhood Hits	64
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

MY18A_HUMAN
NC score	0.055265 (rank : 382)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	345	Target Neighborhood Hits	1929	Shared Neighborhood Hits	142
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

BAZ2A_HUMAN
NC score	0.055126 (rank : 383)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	345	Target Neighborhood Hits	780	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

HMMR_HUMAN
NC score	0.055049 (rank : 384)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	345	Target Neighborhood Hits	1082	Shared Neighborhood Hits	108
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

GCC1_MOUSE
NC score	0.054984 (rank : 385)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	345	Target Neighborhood Hits	777	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

LRSM1_HUMAN
NC score	0.054920 (rank : 386)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	345	Target Neighborhood Hits	1078	Shared Neighborhood Hits	158
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

RNF13_MOUSE
NC score	0.054867 (rank : 387)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	345	Target Neighborhood Hits	164	Shared Neighborhood Hits	56
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

PJA1_MOUSE
NC score	0.054858 (rank : 388)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	345	Target Neighborhood Hits	145	Shared Neighborhood Hits	47
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

MYOM1_HUMAN
NC score	0.054689 (rank : 389)	θ value	0.0431538 (rank : 157)
Query Neighborhood Hits	345	Target Neighborhood Hits	405	Shared Neighborhood Hits	28
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

TRHY_HUMAN
NC score	0.054682 (rank : 390)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	345	Target Neighborhood Hits	1385	Shared Neighborhood Hits	115
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

PF21A_HUMAN
NC score	0.054623 (rank : 391)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	345	Target Neighborhood Hits	303	Shared Neighborhood Hits	33
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

IFT81_HUMAN
NC score	0.054599 (rank : 392)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	345	Target Neighborhood Hits	893	Shared Neighborhood Hits	102
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

CASP_MOUSE
NC score	0.054493 (rank : 393)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	345	Target Neighborhood Hits	1152	Shared Neighborhood Hits	112
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

PIBF1_HUMAN
NC score	0.054363 (rank : 394)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	345	Target Neighborhood Hits	1041	Shared Neighborhood Hits	107
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

UACA_HUMAN
NC score	0.054290 (rank : 395)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	345	Target Neighborhood Hits	1622	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

BPAEA_MOUSE
NC score	0.054204 (rank : 396)	θ value	5.27518 (rank : 299)
Query Neighborhood Hits	345	Target Neighborhood Hits	1480	Shared Neighborhood Hits	129
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGA1_HUMAN
NC score	0.054047 (rank : 397)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	345	Target Neighborhood Hits	1222	Shared Neighborhood Hits	115
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

DESP_HUMAN
NC score	0.054032 (rank : 398)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	345	Target Neighborhood Hits	1470	Shared Neighborhood Hits	122
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CI093_HUMAN
NC score	0.053998 (rank : 399)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	345	Target Neighborhood Hits	1088	Shared Neighborhood Hits	107
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

PF21A_MOUSE
NC score	0.053946 (rank : 400)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	345	Target Neighborhood Hits	285	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

CN145_HUMAN
NC score	0.053918 (rank : 401)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	345	Target Neighborhood Hits	1196	Shared Neighborhood Hits	118
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

PDL2_MOUSE
NC score	0.053877 (rank : 402)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	345	Target Neighborhood Hits	116	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

CE152_HUMAN
NC score	0.053862 (rank : 403)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	345	Target Neighborhood Hits	976	Shared Neighborhood Hits	102
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CASP_HUMAN
NC score	0.053606 (rank : 404)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	345	Target Neighborhood Hits	1131	Shared Neighborhood Hits	112
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

LZTS2_MOUSE
NC score	0.053591 (rank : 405)	θ value	0.813845 (rank : 226)
Query Neighborhood Hits	345	Target Neighborhood Hits	423	Shared Neighborhood Hits	65
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

SPAG5_MOUSE
NC score	0.053576 (rank : 406)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	345	Target Neighborhood Hits	612	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

MYO5A_HUMAN
NC score	0.053557 (rank : 407)	θ value	6.88961 (rank : 319)
Query Neighborhood Hits	345	Target Neighborhood Hits	1092	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

CN145_MOUSE
NC score	0.053530 (rank : 408)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	345	Target Neighborhood Hits	916	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CROCC_MOUSE
NC score	0.053476 (rank : 409)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	345	Target Neighborhood Hits	1460	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RN122_MOUSE
NC score	0.053393 (rank : 410)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	345	Target Neighborhood Hits	121	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

MY18A_MOUSE
NC score	0.053242 (rank : 411)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	345	Target Neighborhood Hits	1989	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ZN363_MOUSE
NC score	0.053221 (rank : 412)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	345	Target Neighborhood Hits	134	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN363_HUMAN
NC score	0.053205 (rank : 413)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	345	Target Neighborhood Hits	162	Shared Neighborhood Hits	28
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

CCD27_HUMAN
NC score	0.053014 (rank : 414)	θ value	8.99809 (rank : 332)
Query Neighborhood Hits	345	Target Neighborhood Hits	594	Shared Neighborhood Hits	82
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

UACA_MOUSE
NC score	0.052778 (rank : 415)	θ value	0.0736092 (rank : 173)
Query Neighborhood Hits	345	Target Neighborhood Hits	1620	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

MYH14_HUMAN
NC score	0.052754 (rank : 416)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	345	Target Neighborhood Hits	995	Shared Neighborhood Hits	100
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

BIRC2_MOUSE
NC score	0.052669 (rank : 417)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	345	Target Neighborhood Hits	137	Shared Neighborhood Hits	78
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

SP110_HUMAN
NC score	0.052664 (rank : 418)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	345	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

ARI2_HUMAN
NC score	0.052533 (rank : 419)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	345	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ZN364_HUMAN
NC score	0.052446 (rank : 420)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	345	Target Neighborhood Hits	140	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

REST_MOUSE
NC score	0.052302 (rank : 421)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	345	Target Neighborhood Hits	1506	Shared Neighborhood Hits	125
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RN165_HUMAN
NC score	0.052225 (rank : 422)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	345	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

CEP55_MOUSE
NC score	0.052110 (rank : 423)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	345	Target Neighborhood Hits	693	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

PDL1_HUMAN
NC score	0.052055 (rank : 424)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	345	Target Neighborhood Hits	195	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

ERC2_HUMAN
NC score	0.052011 (rank : 425)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	345	Target Neighborhood Hits	1156	Shared Neighborhood Hits	105
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

TMF1_HUMAN
NC score	0.051767 (rank : 426)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	345	Target Neighborhood Hits	987	Shared Neighborhood Hits	105
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

ERC2_MOUSE
NC score	0.051485 (rank : 427)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	345	Target Neighborhood Hits	1166	Shared Neighborhood Hits	104
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

RAD50_HUMAN
NC score	0.051434 (rank : 428)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	345	Target Neighborhood Hits	1317	Shared Neighborhood Hits	108
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

MYOM1_MOUSE
NC score	0.051375 (rank : 429)	θ value	0.47712 (rank : 211)
Query Neighborhood Hits	345	Target Neighborhood Hits	415	Shared Neighborhood Hits	27
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

RN126_MOUSE
NC score	0.051317 (rank : 430)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	345	Target Neighborhood Hits	143	Shared Neighborhood Hits	61
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

CCD39_MOUSE
NC score	0.051264 (rank : 431)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	345	Target Neighborhood Hits	1026	Shared Neighborhood Hits	101
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

RSF1_HUMAN
NC score	0.051136 (rank : 432)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	345	Target Neighborhood Hits	539	Shared Neighborhood Hits	58
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

GRAP1_MOUSE
NC score	0.051130 (rank : 433)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	345	Target Neighborhood Hits	1234	Shared Neighborhood Hits	117
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

CI039_HUMAN
NC score	0.051098 (rank : 434)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	345	Target Neighborhood Hits	1171	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

RAD50_MOUSE
NC score	0.051051 (rank : 435)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	345	Target Neighborhood Hits	1366	Shared Neighborhood Hits	113
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

IBRD2_HUMAN
NC score	0.051047 (rank : 436)	θ value	0.21417 (rank : 187)
Query Neighborhood Hits	345	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

EP15R_HUMAN
NC score	0.051040 (rank : 437)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	345	Target Neighborhood Hits	1083	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

CYLN2_MOUSE
NC score	0.050865 (rank : 438)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	345	Target Neighborhood Hits	1002	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

ARI2_MOUSE
NC score	0.050864 (rank : 439)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	345	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

CK5P2_HUMAN
NC score	0.050820 (rank : 440)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	345	Target Neighborhood Hits	1433	Shared Neighborhood Hits	118
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

HOOK1_MOUSE
NC score	0.050723 (rank : 441)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	345	Target Neighborhood Hits	910	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

CJ118_MOUSE
NC score	0.050719 (rank : 442)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	345	Target Neighborhood Hits	1132	Shared Neighborhood Hits	104
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CALD1_HUMAN
NC score	0.050606 (rank : 443)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	345	Target Neighborhood Hits	959	Shared Neighborhood Hits	97
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CCD39_HUMAN
NC score	0.050558 (rank : 444)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	345	Target Neighborhood Hits	868	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CT096_HUMAN
NC score	0.050323 (rank : 445)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	345	Target Neighborhood Hits	438	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

T3JAM_MOUSE
NC score	0.050162 (rank : 446)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	345	Target Neighborhood Hits	535	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

NEMO_MOUSE
NC score	0.050123 (rank : 447)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	345	Target Neighborhood Hits	658	Shared Neighborhood Hits	89
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

BICD1_MOUSE
NC score	0.050081 (rank : 448)	θ value	8.99809 (rank : 328)
Query Neighborhood Hits	345	Target Neighborhood Hits	837	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CUTL1_HUMAN
NC score	0.050056 (rank : 449)	θ value	4.03905 (rank : 291)
Query Neighborhood Hits	345	Target Neighborhood Hits	1574	Shared Neighborhood Hits	118
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

SDPR_MOUSE
NC score	0.049442 (rank : 450)	θ value	1.38821 (rank : 250)
Query Neighborhood Hits	345	Target Neighborhood Hits	485	Shared Neighborhood Hits	72
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

DZIP1_HUMAN
NC score	0.048888 (rank : 451)	θ value	1.38821 (rank : 244)
Query Neighborhood Hits	345	Target Neighborhood Hits	675	Shared Neighborhood Hits	66
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

ANR26_MOUSE
NC score	0.047884 (rank : 452)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	345	Target Neighborhood Hits	1554	Shared Neighborhood Hits	123
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

SAS6_HUMAN
NC score	0.047651 (rank : 453)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	345	Target Neighborhood Hits	791	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

LZTS2_HUMAN
NC score	0.047615 (rank : 454)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	345	Target Neighborhood Hits	427	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

RPGR1_HUMAN
NC score	0.046777 (rank : 455)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	345	Target Neighborhood Hits	578	Shared Neighborhood Hits	72
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

BPAEA_HUMAN
NC score	0.046537 (rank : 456)	θ value	5.27518 (rank : 298)
Query Neighborhood Hits	345	Target Neighborhood Hits	1369	Shared Neighborhood Hits	120
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RRBP1_HUMAN
NC score	0.046414 (rank : 457)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	345	Target Neighborhood Hits	1306	Shared Neighborhood Hits	107
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

ABTAP_MOUSE
NC score	0.045943 (rank : 458)	θ value	1.06291 (rank : 231)
Query Neighborhood Hits	345	Target Neighborhood Hits	381	Shared Neighborhood Hits	49
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

DMD_HUMAN
NC score	0.045424 (rank : 459)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	345	Target Neighborhood Hits	1135	Shared Neighborhood Hits	108
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

CTGE2_HUMAN
NC score	0.045142 (rank : 460)	θ value	6.88961 (rank : 313)
Query Neighborhood Hits	345	Target Neighborhood Hits	594	Shared Neighborhood Hits	83
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

CUTL1_MOUSE
NC score	0.044893 (rank : 461)	θ value	6.88961 (rank : 314)
Query Neighborhood Hits	345	Target Neighborhood Hits	1620	Shared Neighborhood Hits	113
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DTBP1_HUMAN
NC score	0.044652 (rank : 462)	θ value	1.06291 (rank : 234)
Query Neighborhood Hits	345	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

HOME1_HUMAN
NC score	0.043915 (rank : 463)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	345	Target Neighborhood Hits	564	Shared Neighborhood Hits	78
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

IBRD2_MOUSE
NC score	0.043818 (rank : 464)	θ value	0.163984 (rank : 181)
Query Neighborhood Hits	345	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

RAI14_HUMAN
NC score	0.042453 (rank : 465)	θ value	2.36792 (rank : 282)
Query Neighborhood Hits	345	Target Neighborhood Hits	1367	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

MOES_MOUSE
NC score	0.042047 (rank : 466)	θ value	2.36792 (rank : 277)
Query Neighborhood Hits	345	Target Neighborhood Hits	923	Shared Neighborhood Hits	99
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

ROBO2_MOUSE
NC score	0.041699 (rank : 467)	θ value	0.00175202 (rank : 132)
Query Neighborhood Hits	345	Target Neighborhood Hits	504	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

HOOK2_MOUSE
NC score	0.041592 (rank : 468)	θ value	6.88961 (rank : 318)
Query Neighborhood Hits	345	Target Neighborhood Hits	736	Shared Neighborhood Hits	85
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

ROBO2_HUMAN
NC score	0.041288 (rank : 469)	θ value	0.00175202 (rank : 131)
Query Neighborhood Hits	345	Target Neighborhood Hits	479	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SDPR_HUMAN
NC score	0.040823 (rank : 470)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	345	Target Neighborhood Hits	337	Shared Neighborhood Hits	60
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

MOES_HUMAN
NC score	0.040780 (rank : 471)	θ value	0.813845 (rank : 227)
Query Neighborhood Hits	345	Target Neighborhood Hits	892	Shared Neighborhood Hits	97
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

ZN645_HUMAN
NC score	0.040631 (rank : 472)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	345	Target Neighborhood Hits	265	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

HOME1_MOUSE
NC score	0.040067 (rank : 473)	θ value	6.88961 (rank : 317)
Query Neighborhood Hits	345	Target Neighborhood Hits	630	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

RADI_MOUSE
NC score	0.038676 (rank : 474)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	345	Target Neighborhood Hits	773	Shared Neighborhood Hits	88
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

CN004_HUMAN
NC score	0.038368 (rank : 475)	θ value	2.36792 (rank : 269)
Query Neighborhood Hits	345	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

CN004_MOUSE
NC score	0.037514 (rank : 476)	θ value	2.36792 (rank : 270)
Query Neighborhood Hits	345	Target Neighborhood Hits	105	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

RADI_HUMAN
NC score	0.036702 (rank : 477)	θ value	2.36792 (rank : 281)
Query Neighborhood Hits	345	Target Neighborhood Hits	741	Shared Neighborhood Hits	89
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

SPAT2_HUMAN
NC score	0.035349 (rank : 478)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	345	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

KIF4A_HUMAN
NC score	0.035142 (rank : 479)	θ value	1.38821 (rank : 245)
Query Neighborhood Hits	345	Target Neighborhood Hits	1159	Shared Neighborhood Hits	102
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

PHF14_MOUSE
NC score	0.032718 (rank : 480)	θ value	6.88961 (rank : 322)
Query Neighborhood Hits	345	Target Neighborhood Hits	342	Shared Neighborhood Hits	56
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PLDN_MOUSE
NC score	0.031972 (rank : 481)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	345	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0C0, Q3TUT4, Q91VG4	Gene names	Pldn, P2, Pa
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein) (Syntaxin 13-interacting protein).

UB7I4_MOUSE
NC score	0.031644 (rank : 482)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	345	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

PLDN_HUMAN
NC score	0.031472 (rank : 483)	θ value	6.88961 (rank : 323)
Query Neighborhood Hits	345	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UL45	Gene names	PLDN, PA
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein).

PLCB3_MOUSE
NC score	0.031356 (rank : 484)	θ value	2.36792 (rank : 278)
Query Neighborhood Hits	345	Target Neighborhood Hits	344	Shared Neighborhood Hits	52
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

AKP8L_HUMAN
NC score	0.029617 (rank : 485)	θ value	0.62314 (rank : 218)
Query Neighborhood Hits	345	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

LAMA4_HUMAN
NC score	0.028398 (rank : 486)	θ value	1.81305 (rank : 258)
Query Neighborhood Hits	345	Target Neighborhood Hits	708	Shared Neighborhood Hits	76
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ROBO3_MOUSE
NC score	0.027626 (rank : 487)	θ value	2.36792 (rank : 284)
Query Neighborhood Hits	345	Target Neighborhood Hits	524	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

TITIN_HUMAN
NC score	0.027245 (rank : 488)	θ value	0.0431538 (rank : 160)
Query Neighborhood Hits	345	Target Neighborhood Hits	2923	Shared Neighborhood Hits	111
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AKP8L_MOUSE
NC score	0.026437 (rank : 489)	θ value	1.38821 (rank : 239)
Query Neighborhood Hits	345	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

PPIP2_HUMAN
NC score	0.025022 (rank : 490)	θ value	8.99809 (rank : 337)
Query Neighborhood Hits	345	Target Neighborhood Hits	254	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

UB7I4_HUMAN
NC score	0.024994 (rank : 491)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	345	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ROBO3_HUMAN
NC score	0.024876 (rank : 492)	θ value	2.36792 (rank : 283)
Query Neighborhood Hits	345	Target Neighborhood Hits	570	Shared Neighborhood Hits	22
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

CCD43_HUMAN
NC score	0.024518 (rank : 493)	θ value	5.27518 (rank : 300)
Query Neighborhood Hits	345	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q96MW1	Gene names	CCDC43
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

ASPP2_HUMAN
NC score	0.024114 (rank : 494)	θ value	6.88961 (rank : 309)
Query Neighborhood Hits	345	Target Neighborhood Hits	1156	Shared Neighborhood Hits	90
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MRCKB_HUMAN
NC score	0.021195 (rank : 495)	θ value	1.06291 (rank : 235)
Query Neighborhood Hits	345	Target Neighborhood Hits	2239	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_MOUSE
NC score	0.021072 (rank : 496)	θ value	1.81305 (rank : 259)
Query Neighborhood Hits	345	Target Neighborhood Hits	2180	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

TEX28_HUMAN
NC score	0.019860 (rank : 497)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	345	Target Neighborhood Hits	62	Shared Neighborhood Hits	16
SwissProt Accessions	O15482	Gene names	CXorf2, TEX28
Domain Architecture	No domain graphic available
Description	Testis-specific protein TEX28.

SPFH1_HUMAN
NC score	0.016240 (rank : 498)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	345	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	O75477	Gene names	SPFH1, C10orf69, KE04, KEO4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (Protein KE04).

PTPRF_HUMAN
NC score	0.016172 (rank : 499)	θ value	2.36792 (rank : 279)
Query Neighborhood Hits	345	Target Neighborhood Hits	489	Shared Neighborhood Hits	23
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

HDAC4_HUMAN
NC score	0.011743 (rank : 500)	θ value	8.99809 (rank : 334)
Query Neighborhood Hits	345	Target Neighborhood Hits	390	Shared Neighborhood Hits	53
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

TNAP3_HUMAN
NC score	0.011243 (rank : 501)	θ value	1.38821 (rank : 252)
Query Neighborhood Hits	345	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

CNTN6_HUMAN
NC score	0.010214 (rank : 502)	θ value	8.99809 (rank : 333)
Query Neighborhood Hits	345	Target Neighborhood Hits	422	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

DNMBP_HUMAN
NC score	0.007554 (rank : 503)	θ value	2.36792 (rank : 273)
Query Neighborhood Hits	345	Target Neighborhood Hits	413	Shared Neighborhood Hits	20
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ATS2_HUMAN
NC score	0.003825 (rank : 504)	θ value	1.38821 (rank : 240)
Query Neighborhood Hits	345	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

PIAS2_MOUSE
NC score	0.002310 (rank : 505)	θ value	8.99809 (rank : 336)
Query Neighborhood Hits	345	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5D8, O54987, Q8C384, Q8CDQ8, Q8K208, Q99JX5, Q9D5W7, Q9QZ63	Gene names	Pias2, Miz1, Piasx
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3).

SH3G3_HUMAN
NC score	0.001905 (rank : 506)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	345	Target Neighborhood Hits	222	Shared Neighborhood Hits	10
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

TLR2_HUMAN
NC score	0.001819 (rank : 507)	θ value	1.81305 (rank : 268)
Query Neighborhood Hits	345	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

TLR2_MOUSE
NC score	-0.000151 (rank : 508)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	345	Target Neighborhood Hits	283	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QUN7, Q3U400, Q9DBC4	Gene names	Tlr2
Domain Architecture
Description	Toll-like receptor 2 precursor (CD282 antigen).

TLR5_MOUSE
NC score	-0.001518 (rank : 509)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	345	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLF7	Gene names	Tlr5
Domain Architecture
Description	Toll-like receptor 5 precursor.

EPHA8_HUMAN
NC score	-0.002065 (rank : 510)	θ value	6.88961 (rank : 315)
Query Neighborhood Hits	345	Target Neighborhood Hits	956	Shared Neighborhood Hits	21
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
NC score	-0.002079 (rank : 511)	θ value	6.88961 (rank : 316)
Query Neighborhood Hits	345	Target Neighborhood Hits	969	Shared Neighborhood Hits	21
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

ZFP14_HUMAN
NC score	-0.010260 (rank : 512)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	345	Target Neighborhood Hits	743	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCL3	Gene names	ZFP14, KIAA1559
Domain Architecture
Description	Zinc finger protein 14 homolog (Zfp-14).