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Network neighborhood for query Sequence : MEFV_MOUSE

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MEFV_MOUSE
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEFV_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	236	Target Neighborhood Hits	236	Shared Neighborhood Hits	236
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_HUMAN
θ value	8.35901e-139 (rank : 2)	NC score	0.774427 (rank : 2)
Query Neighborhood Hits	236	Target Neighborhood Hits	431	Shared Neighborhood Hits	133
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI27_HUMAN
θ value	1.33217e-27 (rank : 3)	NC score	0.715674 (rank : 6)
Query Neighborhood Hits	236	Target Neighborhood Hits	273	Shared Neighborhood Hits	104
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	3.87602e-27 (rank : 4)	NC score	0.715291 (rank : 7)
Query Neighborhood Hits	236	Target Neighborhood Hits	261	Shared Neighborhood Hits	104
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI15_HUMAN
θ value	2.06002e-20 (rank : 5)	NC score	0.727091 (rank : 4)
Query Neighborhood Hits	236	Target Neighborhood Hits	395	Shared Neighborhood Hits	115
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI10_HUMAN
θ value	5.60996e-18 (rank : 6)	NC score	0.721622 (rank : 5)
Query Neighborhood Hits	236	Target Neighborhood Hits	315	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI31_HUMAN
θ value	2.13179e-17 (rank : 7)	NC score	0.731904 (rank : 3)
Query Neighborhood Hits	236	Target Neighborhood Hits	299	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI26_MOUSE
θ value	1.52774e-15 (rank : 8)	NC score	0.710982 (rank : 10)
Query Neighborhood Hits	236	Target Neighborhood Hits	339	Shared Neighborhood Hits	103
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI17_MOUSE
θ value	3.40345e-15 (rank : 9)	NC score	0.689230 (rank : 25)
Query Neighborhood Hits	236	Target Neighborhood Hits	620	Shared Neighborhood Hits	122
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI39_HUMAN
θ value	9.90251e-15 (rank : 10)	NC score	0.672192 (rank : 38)
Query Neighborhood Hits	236	Target Neighborhood Hits	693	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI38_HUMAN
θ value	8.38298e-14 (rank : 11)	NC score	0.694996 (rank : 22)
Query Neighborhood Hits	236	Target Neighborhood Hits	373	Shared Neighborhood Hits	111
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI34_MOUSE
θ value	1.09485e-13 (rank : 12)	NC score	0.714986 (rank : 8)
Query Neighborhood Hits	236	Target Neighborhood Hits	332	Shared Neighborhood Hits	107
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI39_MOUSE
θ value	1.09485e-13 (rank : 13)	NC score	0.672175 (rank : 39)
Query Neighborhood Hits	236	Target Neighborhood Hits	691	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM7_MOUSE
θ value	1.09485e-13 (rank : 14)	NC score	0.704588 (rank : 13)
Query Neighborhood Hits	236	Target Neighborhood Hits	358	Shared Neighborhood Hits	112
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM6_MOUSE
θ value	1.86753e-13 (rank : 15)	NC score	0.705724 (rank : 12)
Query Neighborhood Hits	236	Target Neighborhood Hits	451	Shared Neighborhood Hits	120
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI10_MOUSE
θ value	3.18553e-13 (rank : 16)	NC score	0.711567 (rank : 9)
Query Neighborhood Hits	236	Target Neighborhood Hits	285	Shared Neighborhood Hits	100
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI11_HUMAN
θ value	2.69671e-12 (rank : 17)	NC score	0.683550 (rank : 30)
Query Neighborhood Hits	236	Target Neighborhood Hits	316	Shared Neighborhood Hits	100
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

RO52_HUMAN
θ value	1.02475e-11 (rank : 18)	NC score	0.679302 (rank : 35)
Query Neighborhood Hits	236	Target Neighborhood Hits	419	Shared Neighborhood Hits	117
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI43_HUMAN
θ value	1.02475e-11 (rank : 19)	NC score	0.698278 (rank : 17)
Query Neighborhood Hits	236	Target Neighborhood Hits	341	Shared Neighborhood Hits	105
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRIM7_HUMAN
θ value	1.02475e-11 (rank : 20)	NC score	0.698501 (rank : 16)
Query Neighborhood Hits	236	Target Neighborhood Hits	336	Shared Neighborhood Hits	109
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI60_HUMAN
θ value	1.33837e-11 (rank : 21)	NC score	0.683758 (rank : 29)
Query Neighborhood Hits	236	Target Neighborhood Hits	357	Shared Neighborhood Hits	104
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI26_HUMAN
θ value	2.28291e-11 (rank : 22)	NC score	0.708730 (rank : 11)
Query Neighborhood Hits	236	Target Neighborhood Hits	335	Shared Neighborhood Hits	101
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI41_HUMAN
θ value	8.67504e-11 (rank : 23)	NC score	0.701531 (rank : 14)
Query Neighborhood Hits	236	Target Neighborhood Hits	349	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM5_HUMAN
θ value	5.62301e-10 (rank : 24)	NC score	0.699734 (rank : 15)
Query Neighborhood Hits	236	Target Neighborhood Hits	424	Shared Neighborhood Hits	115
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI11_MOUSE
θ value	7.34386e-10 (rank : 25)	NC score	0.683078 (rank : 31)
Query Neighborhood Hits	236	Target Neighborhood Hits	329	Shared Neighborhood Hits	105
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI17_HUMAN
θ value	7.34386e-10 (rank : 26)	NC score	0.696788 (rank : 18)
Query Neighborhood Hits	236	Target Neighborhood Hits	318	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI68_MOUSE
θ value	7.34386e-10 (rank : 27)	NC score	0.682030 (rank : 33)
Query Neighborhood Hits	236	Target Neighborhood Hits	356	Shared Neighborhood Hits	114
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

RO52_MOUSE
θ value	1.25267e-09 (rank : 28)	NC score	0.678634 (rank : 37)
Query Neighborhood Hits	236	Target Neighborhood Hits	360	Shared Neighborhood Hits	107
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

ASC_MOUSE
θ value	1.63604e-09 (rank : 29)	NC score	0.319599 (rank : 121)
Query Neighborhood Hits	236	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

TRIM6_HUMAN
θ value	1.63604e-09 (rank : 30)	NC score	0.696338 (rank : 19)
Query Neighborhood Hits	236	Target Neighborhood Hits	412	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM4_HUMAN
θ value	2.13673e-09 (rank : 31)	NC score	0.693817 (rank : 23)
Query Neighborhood Hits	236	Target Neighborhood Hits	321	Shared Neighborhood Hits	104
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI40_HUMAN
θ value	4.76016e-09 (rank : 32)	NC score	0.681286 (rank : 34)
Query Neighborhood Hits	236	Target Neighborhood Hits	279	Shared Neighborhood Hits	94
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI34_HUMAN
θ value	1.06045e-08 (rank : 33)	NC score	0.695105 (rank : 21)
Query Neighborhood Hits	236	Target Neighborhood Hits	416	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI68_HUMAN
θ value	1.38499e-08 (rank : 34)	NC score	0.682259 (rank : 32)
Query Neighborhood Hits	236	Target Neighborhood Hits	267	Shared Neighborhood Hits	98
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

ASC_HUMAN
θ value	1.80886e-08 (rank : 35)	NC score	0.297944 (rank : 127)
Query Neighborhood Hits	236	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

TRI35_HUMAN
θ value	1.80886e-08 (rank : 36)	NC score	0.666720 (rank : 40)
Query Neighborhood Hits	236	Target Neighborhood Hits	382	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

NAL12_HUMAN
θ value	2.36244e-08 (rank : 37)	NC score	0.186891 (rank : 178)
Query Neighborhood Hits	236	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

TRI12_MOUSE
θ value	2.36244e-08 (rank : 38)	NC score	0.696214 (rank : 20)
Query Neighborhood Hits	236	Target Neighborhood Hits	387	Shared Neighborhood Hits	109
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI60_MOUSE
θ value	2.36244e-08 (rank : 39)	NC score	0.678932 (rank : 36)
Query Neighborhood Hits	236	Target Neighborhood Hits	240	Shared Neighborhood Hits	101
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

NAL10_HUMAN
θ value	3.08544e-08 (rank : 40)	NC score	0.226271 (rank : 151)
Query Neighborhood Hits	236	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

CIAS1_MOUSE
θ value	5.26297e-08 (rank : 41)	NC score	0.194135 (rank : 172)
Query Neighborhood Hits	236	Target Neighborhood Hits	67	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

TRI22_HUMAN
θ value	6.87365e-08 (rank : 42)	NC score	0.690961 (rank : 24)
Query Neighborhood Hits	236	Target Neighborhood Hits	396	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI50_MOUSE
θ value	3.41135e-07 (rank : 43)	NC score	0.650365 (rank : 42)
Query Neighborhood Hits	236	Target Neighborhood Hits	326	Shared Neighborhood Hits	110
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

CIAS1_HUMAN
θ value	5.81887e-07 (rank : 44)	NC score	0.192048 (rank : 173)
Query Neighborhood Hits	236	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

TRI35_MOUSE
θ value	7.59969e-07 (rank : 45)	NC score	0.657603 (rank : 41)
Query Neighborhood Hits	236	Target Neighborhood Hits	465	Shared Neighborhood Hits	110
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI49_HUMAN
θ value	1.29631e-06 (rank : 46)	NC score	0.687195 (rank : 27)
Query Neighborhood Hits	236	Target Neighborhood Hits	199	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI30_MOUSE
θ value	4.92598e-06 (rank : 47)	NC score	0.687078 (rank : 28)
Query Neighborhood Hits	236	Target Neighborhood Hits	434	Shared Neighborhood Hits	114
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI52_HUMAN
θ value	1.43324e-05 (rank : 48)	NC score	0.687678 (rank : 26)
Query Neighborhood Hits	236	Target Neighborhood Hits	213	Shared Neighborhood Hits	90
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI36_MOUSE
θ value	1.87187e-05 (rank : 49)	NC score	0.412032 (rank : 108)
Query Neighborhood Hits	236	Target Neighborhood Hits	266	Shared Neighborhood Hits	108
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI36_HUMAN
θ value	2.44474e-05 (rank : 50)	NC score	0.421608 (rank : 107)
Query Neighborhood Hits	236	Target Neighborhood Hits	282	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRIM8_HUMAN
θ value	5.44631e-05 (rank : 51)	NC score	0.538301 (rank : 58)
Query Neighborhood Hits	236	Target Neighborhood Hits	650	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

NALP4_HUMAN
θ value	0.000121331 (rank : 52)	NC score	0.171444 (rank : 187)
Query Neighborhood Hits	236	Target Neighborhood Hits	81	Shared Neighborhood Hits	14
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

TRIM8_MOUSE
θ value	0.000121331 (rank : 53)	NC score	0.539030 (rank : 56)
Query Neighborhood Hits	236	Target Neighborhood Hits	674	Shared Neighborhood Hits	128
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TIF1A_HUMAN
θ value	0.000270298 (rank : 54)	NC score	0.237250 (rank : 147)
Query Neighborhood Hits	236	Target Neighborhood Hits	327	Shared Neighborhood Hits	81
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRI29_MOUSE
θ value	0.00035302 (rank : 55)	NC score	0.449776 (rank : 93)
Query Neighborhood Hits	236	Target Neighborhood Hits	306	Shared Neighborhood Hits	100
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI46_MOUSE
θ value	0.00035302 (rank : 56)	NC score	0.432888 (rank : 103)
Query Neighborhood Hits	236	Target Neighborhood Hits	287	Shared Neighborhood Hits	108
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI50_HUMAN
θ value	0.00035302 (rank : 57)	NC score	0.639997 (rank : 43)
Query Neighborhood Hits	236	Target Neighborhood Hits	294	Shared Neighborhood Hits	104
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI73_HUMAN
θ value	0.000461057 (rank : 58)	NC score	0.634464 (rank : 45)
Query Neighborhood Hits	236	Target Neighborhood Hits	258	Shared Neighborhood Hits	103
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TIF1A_MOUSE
θ value	0.000786445 (rank : 59)	NC score	0.216170 (rank : 159)
Query Neighborhood Hits	236	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI32_HUMAN
θ value	0.000786445 (rank : 60)	NC score	0.512785 (rank : 68)
Query Neighborhood Hits	236	Target Neighborhood Hits	264	Shared Neighborhood Hits	97
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI74_HUMAN
θ value	0.000786445 (rank : 61)	NC score	0.635388 (rank : 44)
Query Neighborhood Hits	236	Target Neighborhood Hits	249	Shared Neighborhood Hits	103
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI32_MOUSE
θ value	0.00102713 (rank : 62)	NC score	0.509973 (rank : 70)
Query Neighborhood Hits	236	Target Neighborhood Hits	271	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

NALP6_MOUSE
θ value	0.00134147 (rank : 63)	NC score	0.176681 (rank : 185)
Query Neighborhood Hits	236	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP6_HUMAN
θ value	0.00175202 (rank : 64)	NC score	0.189378 (rank : 176)
Query Neighborhood Hits	236	Target Neighborhood Hits	52	Shared Neighborhood Hits	15
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

TRI13_MOUSE
θ value	0.00175202 (rank : 65)	NC score	0.593784 (rank : 49)
Query Neighborhood Hits	236	Target Neighborhood Hits	282	Shared Neighborhood Hits	102
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI59_MOUSE
θ value	0.00175202 (rank : 66)	NC score	0.579593 (rank : 51)
Query Neighborhood Hits	236	Target Neighborhood Hits	292	Shared Neighborhood Hits	103
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI46_HUMAN
θ value	0.00298849 (rank : 67)	NC score	0.430219 (rank : 104)
Query Neighborhood Hits	236	Target Neighborhood Hits	291	Shared Neighborhood Hits	109
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI62_HUMAN
θ value	0.00298849 (rank : 68)	NC score	0.629445 (rank : 46)
Query Neighborhood Hits	236	Target Neighborhood Hits	584	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI44_MOUSE
θ value	0.00390308 (rank : 69)	NC score	0.523360 (rank : 64)
Query Neighborhood Hits	236	Target Neighborhood Hits	327	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

NALP5_HUMAN
θ value	0.00665767 (rank : 70)	NC score	0.152588 (rank : 192)
Query Neighborhood Hits	236	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

TIF1G_HUMAN
θ value	0.00665767 (rank : 71)	NC score	0.292476 (rank : 131)
Query Neighborhood Hits	236	Target Neighborhood Hits	410	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	0.00665767 (rank : 72)	NC score	0.289334 (rank : 132)
Query Neighborhood Hits	236	Target Neighborhood Hits	498	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI59_HUMAN
θ value	0.00869519 (rank : 73)	NC score	0.576543 (rank : 52)
Query Neighborhood Hits	236	Target Neighborhood Hits	307	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

SRRM2_HUMAN
θ value	0.0113563 (rank : 74)	NC score	0.064267 (rank : 284)
Query Neighborhood Hits	236	Target Neighborhood Hits	1296	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRI14_MOUSE
θ value	0.0113563 (rank : 75)	NC score	0.546052 (rank : 54)
Query Neighborhood Hits	236	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI44_HUMAN
θ value	0.0113563 (rank : 76)	NC score	0.510842 (rank : 69)
Query Neighborhood Hits	236	Target Neighborhood Hits	393	Shared Neighborhood Hits	97
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

BSPRY_HUMAN
θ value	0.0148317 (rank : 77)	NC score	0.516477 (rank : 65)
Query Neighborhood Hits	236	Target Neighborhood Hits	115	Shared Neighborhood Hits	70
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRIM1_HUMAN
θ value	0.0148317 (rank : 78)	NC score	0.443170 (rank : 99)
Query Neighborhood Hits	236	Target Neighborhood Hits	345	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.0148317 (rank : 79)	NC score	0.439606 (rank : 100)
Query Neighborhood Hits	236	Target Neighborhood Hits	361	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

LAMB2_HUMAN
θ value	0.0193708 (rank : 80)	NC score	0.023383 (rank : 365)
Query Neighborhood Hits	236	Target Neighborhood Hits	692	Shared Neighborhood Hits	26
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

NAL10_MOUSE
θ value	0.0193708 (rank : 81)	NC score	0.189148 (rank : 177)
Query Neighborhood Hits	236	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

TRI13_HUMAN
θ value	0.0252991 (rank : 82)	NC score	0.590091 (rank : 50)
Query Neighborhood Hits	236	Target Neighborhood Hits	274	Shared Neighborhood Hits	98
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI14_HUMAN
θ value	0.0252991 (rank : 83)	NC score	0.539723 (rank : 55)
Query Neighborhood Hits	236	Target Neighborhood Hits	143	Shared Neighborhood Hits	92
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI45_MOUSE
θ value	0.0252991 (rank : 84)	NC score	0.272165 (rank : 138)
Query Neighborhood Hits	236	Target Neighborhood Hits	155	Shared Neighborhood Hits	82
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

CP250_HUMAN
θ value	0.0330416 (rank : 85)	NC score	0.063362 (rank : 285)
Query Neighborhood Hits	236	Target Neighborhood Hits	1805	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

IFT74_HUMAN
θ value	0.0330416 (rank : 86)	NC score	0.049573 (rank : 313)
Query Neighborhood Hits	236	Target Neighborhood Hits	949	Shared Neighborhood Hits	51
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

EP15R_HUMAN
θ value	0.0563607 (rank : 87)	NC score	0.045465 (rank : 320)
Query Neighborhood Hits	236	Target Neighborhood Hits	1083	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

TRI25_HUMAN
θ value	0.0563607 (rank : 88)	NC score	0.477295 (rank : 76)
Query Neighborhood Hits	236	Target Neighborhood Hits	472	Shared Neighborhood Hits	113
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI55_HUMAN
θ value	0.0563607 (rank : 89)	NC score	0.506017 (rank : 71)
Query Neighborhood Hits	236	Target Neighborhood Hits	292	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRIM2_HUMAN
θ value	0.0563607 (rank : 90)	NC score	0.456327 (rank : 84)
Query Neighborhood Hits	236	Target Neighborhood Hits	330	Shared Neighborhood Hits	103
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.0563607 (rank : 91)	NC score	0.455114 (rank : 86)
Query Neighborhood Hits	236	Target Neighborhood Hits	331	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

NFH_HUMAN
θ value	0.0736092 (rank : 92)	NC score	0.030097 (rank : 351)
Query Neighborhood Hits	236	Target Neighborhood Hits	1242	Shared Neighborhood Hits	57
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TRI48_HUMAN
θ value	0.0736092 (rank : 93)	NC score	0.614944 (rank : 48)
Query Neighborhood Hits	236	Target Neighborhood Hits	192	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRIM3_MOUSE
θ value	0.0736092 (rank : 94)	NC score	0.469034 (rank : 81)
Query Neighborhood Hits	236	Target Neighborhood Hits	351	Shared Neighborhood Hits	107
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI54_HUMAN
θ value	0.0961366 (rank : 95)	NC score	0.484213 (rank : 73)
Query Neighborhood Hits	236	Target Neighborhood Hits	209	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI63_HUMAN
θ value	0.0961366 (rank : 96)	NC score	0.513944 (rank : 67)
Query Neighborhood Hits	236	Target Neighborhood Hits	298	Shared Neighborhood Hits	110
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM3_HUMAN
θ value	0.0961366 (rank : 97)	NC score	0.462729 (rank : 82)
Query Neighborhood Hits	236	Target Neighborhood Hits	357	Shared Neighborhood Hits	106
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

GCC2_MOUSE
θ value	0.125558 (rank : 98)	NC score	0.058573 (rank : 289)
Query Neighborhood Hits	236	Target Neighborhood Hits	1619	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

APC_MOUSE
θ value	0.21417 (rank : 99)	NC score	0.037541 (rank : 330)
Query Neighborhood Hits	236	Target Neighborhood Hits	441	Shared Neighborhood Hits	33
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

GATA5_HUMAN
θ value	0.21417 (rank : 100)	NC score	0.022592 (rank : 367)
Query Neighborhood Hits	236	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

HDAC5_HUMAN
θ value	0.21417 (rank : 101)	NC score	0.033409 (rank : 342)
Query Neighborhood Hits	236	Target Neighborhood Hits	353	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

MEGF8_HUMAN
θ value	0.21417 (rank : 102)	NC score	0.026351 (rank : 358)
Query Neighborhood Hits	236	Target Neighborhood Hits	528	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TRI54_MOUSE
θ value	0.21417 (rank : 103)	NC score	0.483869 (rank : 74)
Query Neighborhood Hits	236	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI56_MOUSE
θ value	0.21417 (rank : 104)	NC score	0.355992 (rank : 113)
Query Neighborhood Hits	236	Target Neighborhood Hits	255	Shared Neighborhood Hits	97
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

CSKI2_MOUSE
θ value	0.279714 (rank : 105)	NC score	0.013275 (rank : 390)
Query Neighborhood Hits	236	Target Neighborhood Hits	812	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DMP1_MOUSE
θ value	0.279714 (rank : 106)	NC score	0.039262 (rank : 328)
Query Neighborhood Hits	236	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

NALP2_HUMAN
θ value	0.279714 (rank : 107)	NC score	0.149151 (rank : 196)
Query Neighborhood Hits	236	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

TRI45_HUMAN
θ value	0.279714 (rank : 108)	NC score	0.277380 (rank : 136)
Query Neighborhood Hits	236	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

STK10_HUMAN
θ value	0.365318 (rank : 109)	NC score	0.012819 (rank : 393)
Query Neighborhood Hits	236	Target Neighborhood Hits	1921	Shared Neighborhood Hits	74
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TRI63_MOUSE
θ value	0.365318 (rank : 110)	NC score	0.516176 (rank : 66)
Query Neighborhood Hits	236	Target Neighborhood Hits	240	Shared Neighborhood Hits	104
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRIM9_HUMAN
θ value	0.365318 (rank : 111)	NC score	0.359203 (rank : 111)
Query Neighborhood Hits	236	Target Neighborhood Hits	294	Shared Neighborhood Hits	96
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	0.365318 (rank : 112)	NC score	0.357692 (rank : 112)
Query Neighborhood Hits	236	Target Neighborhood Hits	274	Shared Neighborhood Hits	97
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

CBLC_MOUSE
θ value	0.47712 (rank : 113)	NC score	0.091327 (rank : 247)
Query Neighborhood Hits	236	Target Neighborhood Hits	186	Shared Neighborhood Hits	49
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CLCN1_HUMAN
θ value	0.47712 (rank : 114)	NC score	0.016120 (rank : 383)
Query Neighborhood Hits	236	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

MDC1_MOUSE
θ value	0.47712 (rank : 115)	NC score	0.033444 (rank : 341)
Query Neighborhood Hits	236	Target Neighborhood Hits	998	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MEGF8_MOUSE
θ value	0.47712 (rank : 116)	NC score	0.024452 (rank : 362)
Query Neighborhood Hits	236	Target Neighborhood Hits	520	Shared Neighborhood Hits	10
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NPBL_MOUSE
θ value	0.47712 (rank : 117)	NC score	0.033978 (rank : 334)
Query Neighborhood Hits	236	Target Neighborhood Hits	1041	Shared Neighborhood Hits	43
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PRGC1_MOUSE
θ value	0.47712 (rank : 118)	NC score	0.030407 (rank : 349)
Query Neighborhood Hits	236	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

TRI18_HUMAN
θ value	0.47712 (rank : 119)	NC score	0.454704 (rank : 87)
Query Neighborhood Hits	236	Target Neighborhood Hits	307	Shared Neighborhood Hits	109
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	0.47712 (rank : 120)	NC score	0.443466 (rank : 97)
Query Neighborhood Hits	236	Target Neighborhood Hits	292	Shared Neighborhood Hits	108
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI56_HUMAN
θ value	0.47712 (rank : 121)	NC score	0.352942 (rank : 114)
Query Neighborhood Hits	236	Target Neighborhood Hits	339	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

CNOT3_MOUSE
θ value	0.62314 (rank : 122)	NC score	0.034592 (rank : 332)
Query Neighborhood Hits	236	Target Neighborhood Hits	504	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

IFT74_MOUSE
θ value	0.62314 (rank : 123)	NC score	0.048801 (rank : 315)
Query Neighborhood Hits	236	Target Neighborhood Hits	939	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

STMN1_MOUSE
θ value	0.62314 (rank : 124)	NC score	0.031426 (rank : 346)
Query Neighborhood Hits	236	Target Neighborhood Hits	560	Shared Neighborhood Hits	36
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

TIF1B_MOUSE
θ value	0.62314 (rank : 125)	NC score	0.253171 (rank : 141)
Query Neighborhood Hits	236	Target Neighborhood Hits	276	Shared Neighborhood Hits	85
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI37_HUMAN
θ value	0.62314 (rank : 126)	NC score	0.470057 (rank : 78)
Query Neighborhood Hits	236	Target Neighborhood Hits	307	Shared Neighborhood Hits	110
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	0.62314 (rank : 127)	NC score	0.469956 (rank : 79)
Query Neighborhood Hits	236	Target Neighborhood Hits	316	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

CCD21_MOUSE
θ value	0.813845 (rank : 128)	NC score	0.039530 (rank : 327)
Query Neighborhood Hits	236	Target Neighborhood Hits	1135	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CENPE_HUMAN
θ value	0.813845 (rank : 129)	NC score	0.048839 (rank : 314)
Query Neighborhood Hits	236	Target Neighborhood Hits	2060	Shared Neighborhood Hits	105
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

STMN1_HUMAN
θ value	0.813845 (rank : 130)	NC score	0.029531 (rank : 353)
Query Neighborhood Hits	236	Target Neighborhood Hits	554	Shared Neighborhood Hits	35
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

TIF1B_HUMAN
θ value	0.813845 (rank : 131)	NC score	0.257744 (rank : 140)
Query Neighborhood Hits	236	Target Neighborhood Hits	312	Shared Neighborhood Hits	88
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

CCNB3_MOUSE
θ value	1.06291 (rank : 132)	NC score	0.019885 (rank : 374)
Query Neighborhood Hits	236	Target Neighborhood Hits	211	Shared Neighborhood Hits	15
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CSKI1_MOUSE
θ value	1.06291 (rank : 133)	NC score	0.013374 (rank : 389)
Query Neighborhood Hits	236	Target Neighborhood Hits	1031	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DDX21_HUMAN
θ value	1.06291 (rank : 134)	NC score	0.007183 (rank : 409)
Query Neighborhood Hits	236	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

PCLO_MOUSE
θ value	1.06291 (rank : 135)	NC score	0.022375 (rank : 368)
Query Neighborhood Hits	236	Target Neighborhood Hits	2275	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SLK_HUMAN
θ value	1.06291 (rank : 136)	NC score	0.013060 (rank : 391)
Query Neighborhood Hits	236	Target Neighborhood Hits	1775	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
θ value	1.06291 (rank : 137)	NC score	0.014314 (rank : 386)
Query Neighborhood Hits	236	Target Neighborhood Hits	1798	Shared Neighborhood Hits	75
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SRRM2_MOUSE
θ value	1.06291 (rank : 138)	NC score	0.047841 (rank : 316)
Query Neighborhood Hits	236	Target Neighborhood Hits	1470	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SSF1_HUMAN
θ value	1.06291 (rank : 139)	NC score	0.028548 (rank : 355)
Query Neighborhood Hits	236	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQ55, Q9BW97, Q9H170	Gene names	PPAN, SSF1
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

SSPO_MOUSE
θ value	1.06291 (rank : 140)	NC score	0.006691 (rank : 411)
Query Neighborhood Hits	236	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TARA_MOUSE
θ value	1.06291 (rank : 141)	NC score	0.051248 (rank : 309)
Query Neighborhood Hits	236	Target Neighborhood Hits	1133	Shared Neighborhood Hits	60
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCOF_HUMAN
θ value	1.06291 (rank : 142)	NC score	0.033063 (rank : 343)
Query Neighborhood Hits	236	Target Neighborhood Hits	543	Shared Neighborhood Hits	32
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CP250_MOUSE
θ value	1.38821 (rank : 143)	NC score	0.050744 (rank : 311)
Query Neighborhood Hits	236	Target Neighborhood Hits	1583	Shared Neighborhood Hits	91
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

NFH_MOUSE
θ value	1.38821 (rank : 144)	NC score	0.023823 (rank : 364)
Query Neighborhood Hits	236	Target Neighborhood Hits	2247	Shared Neighborhood Hits	78
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RP1L1_HUMAN
θ value	1.38821 (rank : 145)	NC score	0.040431 (rank : 324)
Query Neighborhood Hits	236	Target Neighborhood Hits	1072	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TACC2_HUMAN
θ value	1.38821 (rank : 146)	NC score	0.033666 (rank : 336)
Query Neighborhood Hits	236	Target Neighborhood Hits	856	Shared Neighborhood Hits	49
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TRI66_MOUSE
θ value	1.38821 (rank : 147)	NC score	0.131253 (rank : 209)
Query Neighborhood Hits	236	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CCD21_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.036796 (rank : 331)
Query Neighborhood Hits	236	Target Neighborhood Hits	1228	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CTR9_MOUSE
θ value	1.81305 (rank : 149)	NC score	0.024852 (rank : 360)
Query Neighborhood Hits	236	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

FUT8_MOUSE
θ value	1.81305 (rank : 150)	NC score	0.022594 (rank : 366)
Query Neighborhood Hits	236	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

NEUL1_HUMAN
θ value	1.81305 (rank : 151)	NC score	0.073373 (rank : 273)
Query Neighborhood Hits	236	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

STK10_MOUSE
θ value	1.81305 (rank : 152)	NC score	0.012775 (rank : 394)
Query Neighborhood Hits	236	Target Neighborhood Hits	2132	Shared Neighborhood Hits	76
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TRI16_MOUSE
θ value	1.81305 (rank : 153)	NC score	0.470942 (rank : 77)
Query Neighborhood Hits	236	Target Neighborhood Hits	196	Shared Neighborhood Hits	93
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI66_HUMAN
θ value	1.81305 (rank : 154)	NC score	0.128092 (rank : 212)
Query Neighborhood Hits	236	Target Neighborhood Hits	479	Shared Neighborhood Hits	63
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ZBT20_HUMAN
θ value	1.81305 (rank : 155)	NC score	-0.005270 (rank : 422)
Query Neighborhood Hits	236	Target Neighborhood Hits	835	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

BSN_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.040146 (rank : 325)
Query Neighborhood Hits	236	Target Neighborhood Hits	2057	Shared Neighborhood Hits	72
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CLGN_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.015779 (rank : 384)
Query Neighborhood Hits	236	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

DOT1L_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.030537 (rank : 348)
Query Neighborhood Hits	236	Target Neighborhood Hits	660	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GCC2_HUMAN
θ value	2.36792 (rank : 159)	NC score	0.052161 (rank : 305)
Query Neighborhood Hits	236	Target Neighborhood Hits	1558	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

HBP1_HUMAN
θ value	2.36792 (rank : 160)	NC score	0.013682 (rank : 387)
Query Neighborhood Hits	236	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HDAC5_MOUSE
θ value	2.36792 (rank : 161)	NC score	0.024918 (rank : 359)
Query Neighborhood Hits	236	Target Neighborhood Hits	310	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

LAMB2_MOUSE
θ value	2.36792 (rank : 162)	NC score	0.019557 (rank : 376)
Query Neighborhood Hits	236	Target Neighborhood Hits	722	Shared Neighborhood Hits	29
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NEUM_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.031498 (rank : 345)
Query Neighborhood Hits	236	Target Neighborhood Hits	132	Shared Neighborhood Hits	13
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

RBP24_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.052079 (rank : 306)
Query Neighborhood Hits	236	Target Neighborhood Hits	1559	Shared Neighborhood Hits	96
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

TRI25_MOUSE
θ value	2.36792 (rank : 165)	NC score	0.469310 (rank : 80)
Query Neighborhood Hits	236	Target Neighborhood Hits	446	Shared Neighborhood Hits	115
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI42_HUMAN
θ value	2.36792 (rank : 166)	NC score	0.293675 (rank : 129)
Query Neighborhood Hits	236	Target Neighborhood Hits	283	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

AFF4_HUMAN
θ value	3.0926 (rank : 167)	NC score	0.026763 (rank : 357)
Query Neighborhood Hits	236	Target Neighborhood Hits	611	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

BYST_MOUSE
θ value	3.0926 (rank : 168)	NC score	0.019376 (rank : 378)
Query Neighborhood Hits	236	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O54825, Q3THF4, Q3UPY9, Q8VD68	Gene names	Bysl
Domain Architecture
Description	Bystin.

CF010_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.033521 (rank : 339)
Query Neighborhood Hits	236	Target Neighborhood Hits	329	Shared Neighborhood Hits	28
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CK024_HUMAN
θ value	3.0926 (rank : 170)	NC score	0.022112 (rank : 369)
Query Neighborhood Hits	236	Target Neighborhood Hits	408	Shared Neighborhood Hits	18
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

EPN2_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.012918 (rank : 392)
Query Neighborhood Hits	236	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

K1543_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.021597 (rank : 371)
Query Neighborhood Hits	236	Target Neighborhood Hits	435	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NIN_MOUSE
θ value	3.0926 (rank : 173)	NC score	0.044332 (rank : 321)
Query Neighborhood Hits	236	Target Neighborhood Hits	1376	Shared Neighborhood Hits	83
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

ZC3H3_HUMAN
θ value	3.0926 (rank : 174)	NC score	0.020804 (rank : 373)
Query Neighborhood Hits	236	Target Neighborhood Hits	159	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

AFF4_MOUSE
θ value	4.03905 (rank : 175)	NC score	0.028645 (rank : 354)
Query Neighborhood Hits	236	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ARS2_MOUSE
θ value	4.03905 (rank : 176)	NC score	0.016817 (rank : 381)
Query Neighborhood Hits	236	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CCD45_HUMAN
θ value	4.03905 (rank : 177)	NC score	0.027748 (rank : 356)
Query Neighborhood Hits	236	Target Neighborhood Hits	525	Shared Neighborhood Hits	37
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CND1_HUMAN
θ value	4.03905 (rank : 178)	NC score	0.019401 (rank : 377)
Query Neighborhood Hits	236	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q15021, Q8N6U3	Gene names	NCAPD2, CAPD2, CNAP1, KIAA0159
Domain Architecture
Description	Condensin complex subunit 1 (Non-SMC condensin I complex subunit D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (XCAP-D2 homolog).

CP135_MOUSE
θ value	4.03905 (rank : 179)	NC score	0.030540 (rank : 347)
Query Neighborhood Hits	236	Target Neighborhood Hits	1278	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

HUWE1_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.007335 (rank : 408)
Query Neighborhood Hits	236	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

IRX1_HUMAN
θ value	4.03905 (rank : 181)	NC score	0.011863 (rank : 396)
Query Neighborhood Hits	236	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

NEO1_HUMAN
θ value	4.03905 (rank : 182)	NC score	0.002579 (rank : 414)
Query Neighborhood Hits	236	Target Neighborhood Hits	530	Shared Neighborhood Hits	15
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

PCGF6_MOUSE
θ value	4.03905 (rank : 183)	NC score	0.158665 (rank : 189)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

SYBU_HUMAN
θ value	4.03905 (rank : 184)	NC score	0.019785 (rank : 375)
Query Neighborhood Hits	236	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

TENX_HUMAN
θ value	4.03905 (rank : 185)	NC score	0.005321 (rank : 412)
Query Neighborhood Hits	236	Target Neighborhood Hits	789	Shared Neighborhood Hits	21
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TRI47_HUMAN
θ value	4.03905 (rank : 186)	NC score	0.435671 (rank : 101)
Query Neighborhood Hits	236	Target Neighborhood Hits	286	Shared Neighborhood Hits	100
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TXND2_MOUSE
θ value	4.03905 (rank : 187)	NC score	0.030028 (rank : 352)
Query Neighborhood Hits	236	Target Neighborhood Hits	828	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZAR1_HUMAN
θ value	4.03905 (rank : 188)	NC score	0.021130 (rank : 372)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZNF35_HUMAN
θ value	4.03905 (rank : 189)	NC score	-0.006855 (rank : 423)
Query Neighborhood Hits	236	Target Neighborhood Hits	761	Shared Neighborhood Hits	5
SwissProt Accessions	P13682, Q96D01	Gene names	ZNF35
Domain Architecture	No domain graphic available
Description	Zinc finger protein 35 (Zinc finger protein HF.10).

3BP5_HUMAN
θ value	5.27518 (rank : 190)	NC score	0.021986 (rank : 370)
Query Neighborhood Hits	236	Target Neighborhood Hits	375	Shared Neighborhood Hits	27
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

CENPF_HUMAN
θ value	5.27518 (rank : 191)	NC score	0.046471 (rank : 318)
Query Neighborhood Hits	236	Target Neighborhood Hits	1932	Shared Neighborhood Hits	104
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

IRX1_MOUSE
θ value	5.27518 (rank : 192)	NC score	0.011878 (rank : 395)
Query Neighborhood Hits	236	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	P81068, O55120, Q9JLL6	Gene names	Irx1, Irxa1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

IRX2_MOUSE
θ value	5.27518 (rank : 193)	NC score	0.009327 (rank : 405)
Query Neighborhood Hits	236	Target Neighborhood Hits	264	Shared Neighborhood Hits	5
SwissProt Accessions	P81066, O55121, Q9ERN1	Gene names	Irx2, Irxa2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

K0552_HUMAN
θ value	5.27518 (rank : 194)	NC score	0.030218 (rank : 350)
Query Neighborhood Hits	236	Target Neighborhood Hits	442	Shared Neighborhood Hits	35
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

MAP1B_MOUSE
θ value	5.27518 (rank : 195)	NC score	0.033545 (rank : 338)
Query Neighborhood Hits	236	Target Neighborhood Hits	977	Shared Neighborhood Hits	63
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NALP7_HUMAN
θ value	5.27518 (rank : 196)	NC score	0.141454 (rank : 203)
Query Neighborhood Hits	236	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

SET1A_HUMAN
θ value	5.27518 (rank : 197)	NC score	0.016349 (rank : 382)
Query Neighborhood Hits	236	Target Neighborhood Hits	690	Shared Neighborhood Hits	27
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SPEG_MOUSE
θ value	5.27518 (rank : 198)	NC score	-0.001129 (rank : 419)
Query Neighborhood Hits	236	Target Neighborhood Hits	1959	Shared Neighborhood Hits	40
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SWP70_MOUSE
θ value	5.27518 (rank : 199)	NC score	0.038179 (rank : 329)
Query Neighborhood Hits	236	Target Neighborhood Hits	1097	Shared Neighborhood Hits	62
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TCEA2_MOUSE
θ value	5.27518 (rank : 200)	NC score	0.011242 (rank : 400)
Query Neighborhood Hits	236	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QVN7, O08667	Gene names	Tcea2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Protein S-II-T1) (Transcription elongation factor TFIIS.l).

AP3B2_HUMAN
θ value	6.88961 (rank : 201)	NC score	0.007024 (rank : 410)
Query Neighborhood Hits	236	Target Neighborhood Hits	246	Shared Neighborhood Hits	10
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

APOE_MOUSE
θ value	6.88961 (rank : 202)	NC score	0.024501 (rank : 361)
Query Neighborhood Hits	236	Target Neighborhood Hits	319	Shared Neighborhood Hits	28
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

AZI1_HUMAN
θ value	6.88961 (rank : 203)	NC score	0.047628 (rank : 317)
Query Neighborhood Hits	236	Target Neighborhood Hits	1000	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BSN_HUMAN
θ value	6.88961 (rank : 204)	NC score	0.043397 (rank : 322)
Query Neighborhood Hits	236	Target Neighborhood Hits	1537	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSPRY_MOUSE
θ value	6.88961 (rank : 205)	NC score	0.495640 (rank : 72)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	75
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

EEA1_HUMAN
θ value	6.88961 (rank : 206)	NC score	0.042905 (rank : 323)
Query Neighborhood Hits	236	Target Neighborhood Hits	1796	Shared Neighborhood Hits	104
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FBX34_MOUSE
θ value	6.88961 (rank : 207)	NC score	0.011323 (rank : 399)
Query Neighborhood Hits	236	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

MIER1_MOUSE
θ value	6.88961 (rank : 208)	NC score	0.009017 (rank : 407)
Query Neighborhood Hits	236	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

MYH11_MOUSE
θ value	6.88961 (rank : 209)	NC score	0.033621 (rank : 337)
Query Neighborhood Hits	236	Target Neighborhood Hits	1777	Shared Neighborhood Hits	100
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NAB1_MOUSE
θ value	6.88961 (rank : 210)	NC score	0.010064 (rank : 404)
Query Neighborhood Hits	236	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q61122	Gene names	Nab1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1).

NACA_HUMAN
θ value	6.88961 (rank : 211)	NC score	0.011742 (rank : 397)
Query Neighborhood Hits	236	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q13765, Q53A18, Q53G46	Gene names	NACA
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (Hom s 2.02).

NOTC4_HUMAN
θ value	6.88961 (rank : 212)	NC score	0.002209 (rank : 415)
Query Neighborhood Hits	236	Target Neighborhood Hits	905	Shared Neighborhood Hits	11
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

PRP4B_MOUSE
θ value	6.88961 (rank : 213)	NC score	-0.000326 (rank : 418)
Query Neighborhood Hits	236	Target Neighborhood Hits	1040	Shared Neighborhood Hits	24
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

RFTN1_MOUSE
θ value	6.88961 (rank : 214)	NC score	0.010329 (rank : 403)
Query Neighborhood Hits	236	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A0D4, Q3U654, Q3U8P6, Q80US1	Gene names	Rftn1, Kiaa0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein).

SFRS4_MOUSE
θ value	6.88961 (rank : 215)	NC score	0.014700 (rank : 385)
Query Neighborhood Hits	236	Target Neighborhood Hits	406	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TARA_HUMAN
θ value	6.88961 (rank : 216)	NC score	0.045470 (rank : 319)
Query Neighborhood Hits	236	Target Neighborhood Hits	1626	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TERT_HUMAN
θ value	6.88961 (rank : 217)	NC score	0.011178 (rank : 401)
Query Neighborhood Hits	236	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	O14746, O14783, Q2XS35, Q8N6C3	Gene names	TERT, EST2, TCS1, TRT
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (HEST2) (Telomerase-associated protein 2) (TP2).

TXLNG_MOUSE
θ value	6.88961 (rank : 218)	NC score	0.024277 (rank : 363)
Query Neighborhood Hits	236	Target Neighborhood Hits	552	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

ZKSC1_MOUSE
θ value	6.88961 (rank : 219)	NC score	-0.006990 (rank : 424)
Query Neighborhood Hits	236	Target Neighborhood Hits	755	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGS3, Q7TS88, Q8BJ55, Q9CRN6	Gene names	Zkscan1
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1.

AFF1_MOUSE
θ value	8.99809 (rank : 220)	NC score	0.018122 (rank : 380)
Query Neighborhood Hits	236	Target Neighborhood Hits	351	Shared Neighborhood Hits	20
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ANR11_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.018243 (rank : 379)
Query Neighborhood Hits	236	Target Neighborhood Hits	1289	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CEP63_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.034378 (rank : 333)
Query Neighborhood Hits	236	Target Neighborhood Hits	1005	Shared Neighborhood Hits	62
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CNGB1_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.003959 (rank : 413)
Query Neighborhood Hits	236	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

GAK_MOUSE
θ value	8.99809 (rank : 224)	NC score	-0.003223 (rank : 421)
Query Neighborhood Hits	236	Target Neighborhood Hits	964	Shared Neighborhood Hits	13
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GCC1_MOUSE
θ value	8.99809 (rank : 225)	NC score	0.040129 (rank : 326)
Query Neighborhood Hits	236	Target Neighborhood Hits	777	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

HM2L1_HUMAN
θ value	8.99809 (rank : 226)	NC score	0.011682 (rank : 398)
Query Neighborhood Hits	236	Target Neighborhood Hits	130	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

IF2P_HUMAN
θ value	8.99809 (rank : 227)	NC score	0.033842 (rank : 335)
Query Neighborhood Hits	236	Target Neighborhood Hits	889	Shared Neighborhood Hits	53
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

KHK_MOUSE
θ value	8.99809 (rank : 228)	NC score	0.010704 (rank : 402)
Query Neighborhood Hits	236	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P97328, Q91WU8	Gene names	Khk
Domain Architecture
Description	Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase).

LETM1_HUMAN
θ value	8.99809 (rank : 229)	NC score	0.032743 (rank : 344)
Query Neighborhood Hits	236	Target Neighborhood Hits	338	Shared Neighborhood Hits	27
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

MYH11_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.033464 (rank : 340)
Query Neighborhood Hits	236	Target Neighborhood Hits	1806	Shared Neighborhood Hits	106
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NEURL_MOUSE
θ value	8.99809 (rank : 231)	NC score	0.067755 (rank : 280)
Query Neighborhood Hits	236	Target Neighborhood Hits	106	Shared Neighborhood Hits	23
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

PHC1_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.009324 (rank : 406)
Query Neighborhood Hits	236	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

PKHA5_HUMAN
θ value	8.99809 (rank : 233)	NC score	0.013544 (rank : 388)
Query Neighborhood Hits	236	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PLMN_MOUSE
θ value	8.99809 (rank : 234)	NC score	-0.002605 (rank : 420)
Query Neighborhood Hits	236	Target Neighborhood Hits	208	Shared Neighborhood Hits	2
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

ROBO1_HUMAN
θ value	8.99809 (rank : 235)	NC score	0.000730 (rank : 417)
Query Neighborhood Hits	236	Target Neighborhood Hits	529	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ROBO1_MOUSE
θ value	8.99809 (rank : 236)	NC score	0.001019 (rank : 416)
Query Neighborhood Hits	236	Target Neighborhood Hits	559	Shared Neighborhood Hits	13
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

AMFR2_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.102521 (rank : 238)
Query Neighborhood Hits	236	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.099846 (rank : 241)
Query Neighborhood Hits	236	Target Neighborhood Hits	208	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ARD1_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.109092 (rank : 234)
Query Neighborhood Hits	236	Target Neighborhood Hits	621	Shared Neighborhood Hits	75
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.110795 (rank : 231)
Query Neighborhood Hits	236	Target Neighborhood Hits	573	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

AZI1_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.051253 (rank : 308)
Query Neighborhood Hits	236	Target Neighborhood Hits	990	Shared Neighborhood Hits	69
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BARD1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.088921 (rank : 251)
Query Neighborhood Hits	236	Target Neighborhood Hits	427	Shared Neighborhood Hits	55
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.087578 (rank : 253)
Query Neighborhood Hits	236	Target Neighborhood Hits	411	Shared Neighborhood Hits	54
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BFAR_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.342761 (rank : 115)
Query Neighborhood Hits	236	Target Neighborhood Hits	222	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.335611 (rank : 116)
Query Neighborhood Hits	236	Target Neighborhood Hits	232	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BIRC2_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.073312 (rank : 274)
Query Neighborhood Hits	236	Target Neighborhood Hits	142	Shared Neighborhood Hits	49
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.069786 (rank : 276)
Query Neighborhood Hits	236	Target Neighborhood Hits	137	Shared Neighborhood Hits	43
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.074910 (rank : 272)
Query Neighborhood Hits	236	Target Neighborhood Hits	133	Shared Neighborhood Hits	44
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.058995 (rank : 288)
Query Neighborhood Hits	236	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC7_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.206357 (rank : 165)
Query Neighborhood Hits	236	Target Neighborhood Hits	185	Shared Neighborhood Hits	78
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC8_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.094431 (rank : 244)
Query Neighborhood Hits	236	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BRAP_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.064419 (rank : 282)
Query Neighborhood Hits	236	Target Neighborhood Hits	560	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.053071 (rank : 301)
Query Neighborhood Hits	236	Target Neighborhood Hits	409	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRCA1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.333350 (rank : 118)
Query Neighborhood Hits	236	Target Neighborhood Hits	381	Shared Neighborhood Hits	95
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.333668 (rank : 117)
Query Neighborhood Hits	236	Target Neighborhood Hits	436	Shared Neighborhood Hits	108
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRE1A_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.054075 (rank : 297)
Query Neighborhood Hits	236	Target Neighborhood Hits	1071	Shared Neighborhood Hits	95
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.052209 (rank : 304)
Query Neighborhood Hits	236	Target Neighborhood Hits	1025	Shared Neighborhood Hits	91
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1B_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.062238 (rank : 286)
Query Neighborhood Hits	236	Target Neighborhood Hits	1040	Shared Neighborhood Hits	106
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.061777 (rank : 287)
Query Neighborhood Hits	236	Target Neighborhood Hits	970	Shared Neighborhood Hits	101
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BT1A1_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.451374 (rank : 89)
Query Neighborhood Hits	236	Target Neighborhood Hits	322	Shared Neighborhood Hits	61
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.458071 (rank : 83)
Query Neighborhood Hits	236	Target Neighborhood Hits	252	Shared Neighborhood Hits	60
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.447125 (rank : 96)
Query Neighborhood Hits	236	Target Neighborhood Hits	185	Shared Neighborhood Hits	58
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.455906 (rank : 85)
Query Neighborhood Hits	236	Target Neighborhood Hits	191	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.450538 (rank : 91)
Query Neighborhood Hits	236	Target Neighborhood Hits	195	Shared Neighborhood Hits	56
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.449142 (rank : 95)
Query Neighborhood Hits	236	Target Neighborhood Hits	229	Shared Neighborhood Hits	59
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.450784 (rank : 90)
Query Neighborhood Hits	236	Target Neighborhood Hits	233	Shared Neighborhood Hits	60
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.450036 (rank : 92)
Query Neighborhood Hits	236	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.434600 (rank : 102)
Query Neighborhood Hits	236	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.449608 (rank : 94)
Query Neighborhood Hits	236	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

C2TA_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.077010 (rank : 268)
Query Neighborhood Hits	236	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.079689 (rank : 261)
Query Neighborhood Hits	236	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CAR15_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.084297 (rank : 257)
Query Neighborhood Hits	236	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CAR15_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.083943 (rank : 259)
Query Neighborhood Hits	236	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CARD4_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.078895 (rank : 264)
Query Neighborhood Hits	236	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CARD4_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.076378 (rank : 270)
Query Neighborhood Hits	236	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CBLB_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.085600 (rank : 255)
Query Neighborhood Hits	236	Target Neighborhood Hits	261	Shared Neighborhood Hits	61
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.087173 (rank : 254)
Query Neighborhood Hits	236	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.080968 (rank : 260)
Query Neighborhood Hits	236	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBL_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.091993 (rank : 246)
Query Neighborhood Hits	236	Target Neighborhood Hits	353	Shared Neighborhood Hits	69
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.089532 (rank : 249)
Query Neighborhood Hits	236	Target Neighborhood Hits	426	Shared Neighborhood Hits	67
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CHFR_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.214545 (rank : 160)
Query Neighborhood Hits	236	Target Neighborhood Hits	255	Shared Neighborhood Hits	75
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.208112 (rank : 163)
Query Neighborhood Hits	236	Target Neighborhood Hits	264	Shared Neighborhood Hits	74
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CM007_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.133515 (rank : 206)
Query Neighborhood Hits	236	Target Neighborhood Hits	422	Shared Neighborhood Hits	66
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.154749 (rank : 190)
Query Neighborhood Hits	236	Target Neighborhood Hits	416	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CNOT4_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.078903 (rank : 263)
Query Neighborhood Hits	236	Target Neighborhood Hits	207	Shared Neighborhood Hits	30
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.076355 (rank : 271)
Query Neighborhood Hits	236	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

DTX3L_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.078175 (rank : 265)
Query Neighborhood Hits	236	Target Neighborhood Hits	187	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.191249 (rank : 175)
Query Neighborhood Hits	236	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.199055 (rank : 167)
Query Neighborhood Hits	236	Target Neighborhood Hits	202	Shared Neighborhood Hits	69
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

ERMAP_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.523381 (rank : 63)
Query Neighborhood Hits	236	Target Neighborhood Hits	155	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.481246 (rank : 75)
Query Neighborhood Hits	236	Target Neighborhood Hits	231	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

FSD1L_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.067578 (rank : 281)
Query Neighborhood Hits	236	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.084369 (rank : 256)
Query Neighborhood Hits	236	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GOGA4_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.053376 (rank : 298)
Query Neighborhood Hits	236	Target Neighborhood Hits	1939	Shared Neighborhood Hits	118
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGB1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.050936 (rank : 310)
Query Neighborhood Hits	236	Target Neighborhood Hits	2297	Shared Neighborhood Hits	123
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LNX1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.148018 (rank : 197)
Query Neighborhood Hits	236	Target Neighborhood Hits	379	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.151385 (rank : 194)
Query Neighborhood Hits	236	Target Neighborhood Hits	377	Shared Neighborhood Hits	77
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.143960 (rank : 200)
Query Neighborhood Hits	236	Target Neighborhood Hits	389	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.146232 (rank : 198)
Query Neighborhood Hits	236	Target Neighborhood Hits	407	Shared Neighborhood Hits	83
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LRSM1_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.051293 (rank : 307)
Query Neighborhood Hits	236	Target Neighborhood Hits	1078	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MAT1_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.101536 (rank : 239)
Query Neighborhood Hits	236	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.100625 (rank : 240)
Query Neighborhood Hits	236	Target Neighborhood Hits	217	Shared Neighborhood Hits	38
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MGRN1_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.054467 (rank : 296)
Query Neighborhood Hits	236	Target Neighborhood Hits	192	Shared Neighborhood Hits	40
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.054707 (rank : 295)
Query Neighborhood Hits	236	Target Neighborhood Hits	149	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MIB1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.055926 (rank : 291)
Query Neighborhood Hits	236	Target Neighborhood Hits	470	Shared Neighborhood Hits	54
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.055922 (rank : 292)
Query Neighborhood Hits	236	Target Neighborhood Hits	471	Shared Neighborhood Hits	54
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MKRN2_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.052524 (rank : 302)
Query Neighborhood Hits	236	Target Neighborhood Hits	129	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.053255 (rank : 299)
Query Neighborhood Hits	236	Target Neighborhood Hits	130	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MNAB_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.090818 (rank : 248)
Query Neighborhood Hits	236	Target Neighborhood Hits	196	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.089193 (rank : 250)
Query Neighborhood Hits	236	Target Neighborhood Hits	231	Shared Neighborhood Hits	68
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

NAL11_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.126675 (rank : 216)
Query Neighborhood Hits	236	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NAL13_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.126662 (rank : 217)
Query Neighborhood Hits	236	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NAL14_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.143237 (rank : 202)
Query Neighborhood Hits	236	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP1_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.145886 (rank : 199)
Query Neighborhood Hits	236	Target Neighborhood Hits	138	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP5_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.123964 (rank : 221)
Query Neighborhood Hits	236	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NHLC1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.125677 (rank : 218)
Query Neighborhood Hits	236	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.125584 (rank : 219)
Query Neighborhood Hits	236	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCGF2_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.121020 (rank : 222)
Query Neighborhood Hits	236	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.120831 (rank : 223)
Query Neighborhood Hits	236	Target Neighborhood Hits	213	Shared Neighborhood Hits	48
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.131868 (rank : 208)
Query Neighborhood Hits	236	Target Neighborhood Hits	161	Shared Neighborhood Hits	48
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.132640 (rank : 207)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF6_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.149467 (rank : 195)
Query Neighborhood Hits	236	Target Neighborhood Hits	178	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PEX10_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.314255 (rank : 122)
Query Neighborhood Hits	236	Target Neighborhood Hits	255	Shared Neighborhood Hits	69
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PJA1_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.052217 (rank : 303)
Query Neighborhood Hits	236	Target Neighborhood Hits	159	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PML_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.249589 (rank : 142)
Query Neighborhood Hits	236	Target Neighborhood Hits	248	Shared Neighborhood Hits	88
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.221028 (rank : 158)
Query Neighborhood Hits	236	Target Neighborhood Hits	246	Shared Neighborhood Hits	86
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PZRN3_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.116096 (rank : 227)
Query Neighborhood Hits	236	Target Neighborhood Hits	461	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.118243 (rank : 224)
Query Neighborhood Hits	236	Target Neighborhood Hits	447	Shared Neighborhood Hits	84
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.114327 (rank : 229)
Query Neighborhood Hits	236	Target Neighborhood Hits	438	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

R113A_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.138490 (rank : 204)
Query Neighborhood Hits	236	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.151709 (rank : 193)
Query Neighborhood Hits	236	Target Neighborhood Hits	165	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAD18_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.186334 (rank : 179)
Query Neighborhood Hits	236	Target Neighborhood Hits	284	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.208945 (rank : 162)
Query Neighborhood Hits	236	Target Neighborhood Hits	230	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAG1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.247706 (rank : 144)
Query Neighborhood Hits	236	Target Neighborhood Hits	203	Shared Neighborhood Hits	62
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.238434 (rank : 146)
Query Neighborhood Hits	236	Target Neighborhood Hits	189	Shared Neighborhood Hits	65
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RBBP6_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.116676 (rank : 226)
Query Neighborhood Hits	236	Target Neighborhood Hits	1135	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.127898 (rank : 213)
Query Neighborhood Hits	236	Target Neighborhood Hits	1014	Shared Neighborhood Hits	104
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RC3H1_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.128485 (rank : 211)
Query Neighborhood Hits	236	Target Neighborhood Hits	433	Shared Neighborhood Hits	74
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.133824 (rank : 205)
Query Neighborhood Hits	236	Target Neighborhood Hits	244	Shared Neighborhood Hits	70
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RFFL_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.057410 (rank : 290)
Query Neighborhood Hits	236	Target Neighborhood Hits	175	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.055843 (rank : 293)
Query Neighborhood Hits	236	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFPL1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.529583 (rank : 60)
Query Neighborhood Hits	236	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.528756 (rank : 62)
Query Neighborhood Hits	236	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.534234 (rank : 59)
Query Neighborhood Hits	236	Target Neighborhood Hits	134	Shared Neighborhood Hits	71
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFWD2_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.177174 (rank : 183)
Query Neighborhood Hits	236	Target Neighborhood Hits	518	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.176820 (rank : 184)
Query Neighborhood Hits	236	Target Neighborhood Hits	535	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.248050 (rank : 143)
Query Neighborhood Hits	236	Target Neighborhood Hits	219	Shared Neighborhood Hits	76
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.243631 (rank : 145)
Query Neighborhood Hits	236	Target Neighborhood Hits	220	Shared Neighborhood Hits	78
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.224775 (rank : 153)
Query Neighborhood Hits	236	Target Neighborhood Hits	201	Shared Neighborhood Hits	72
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.224847 (rank : 152)
Query Neighborhood Hits	236	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RINI_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.098195 (rank : 242)
Query Neighborhood Hits	236	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.096713 (rank : 243)
Query Neighborhood Hits	236	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RKHD1_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.073236 (rank : 275)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	28
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN123_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.069145 (rank : 279)
Query Neighborhood Hits	236	Target Neighborhood Hits	175	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.069384 (rank : 278)
Query Neighborhood Hits	236	Target Neighborhood Hits	174	Shared Neighborhood Hits	53
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN125_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.294868 (rank : 128)
Query Neighborhood Hits	236	Target Neighborhood Hits	230	Shared Neighborhood Hits	76
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.304585 (rank : 126)
Query Neighborhood Hits	236	Target Neighborhood Hits	220	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN141_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.182035 (rank : 181)
Query Neighborhood Hits	236	Target Neighborhood Hits	199	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.181290 (rank : 182)
Query Neighborhood Hits	236	Target Neighborhood Hits	200	Shared Neighborhood Hits	73
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.198329 (rank : 168)
Query Neighborhood Hits	236	Target Neighborhood Hits	162	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.196767 (rank : 170)
Query Neighborhood Hits	236	Target Neighborhood Hits	161	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN152_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.126843 (rank : 215)
Query Neighborhood Hits	236	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.127158 (rank : 214)
Query Neighborhood Hits	236	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN166_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.304805 (rank : 125)
Query Neighborhood Hits	236	Target Neighborhood Hits	240	Shared Neighborhood Hits	79
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.293610 (rank : 130)
Query Neighborhood Hits	236	Target Neighborhood Hits	248	Shared Neighborhood Hits	79
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.325551 (rank : 119)
Query Neighborhood Hits	236	Target Neighborhood Hits	370	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.309787 (rank : 124)
Query Neighborhood Hits	236	Target Neighborhood Hits	440	Shared Neighborhood Hits	101
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN169_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.262478 (rank : 139)
Query Neighborhood Hits	236	Target Neighborhood Hits	203	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.278559 (rank : 135)
Query Neighborhood Hits	236	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.234551 (rank : 148)
Query Neighborhood Hits	236	Target Neighborhood Hits	119	Shared Neighborhood Hits	64
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.230342 (rank : 149)
Query Neighborhood Hits	236	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.230317 (rank : 150)
Query Neighborhood Hits	236	Target Neighborhood Hits	211	Shared Neighborhood Hits	66
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF19_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.050480 (rank : 312)
Query Neighborhood Hits	236	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF26_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.053123 (rank : 300)
Query Neighborhood Hits	236	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF32_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.084239 (rank : 258)
Query Neighborhood Hits	236	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.077843 (rank : 266)
Query Neighborhood Hits	236	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.076483 (rank : 269)
Query Neighborhood Hits	236	Target Neighborhood Hits	153	Shared Neighborhood Hits	33
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.077444 (rank : 267)
Query Neighborhood Hits	236	Target Neighborhood Hits	160	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF39_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.548556 (rank : 53)
Query Neighborhood Hits	236	Target Neighborhood Hits	200	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF41_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.221068 (rank : 157)
Query Neighborhood Hits	236	Target Neighborhood Hits	226	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.221331 (rank : 156)
Query Neighborhood Hits	236	Target Neighborhood Hits	224	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.213793 (rank : 161)
Query Neighborhood Hits	236	Target Neighborhood Hits	212	Shared Neighborhood Hits	57
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.207568 (rank : 164)
Query Neighborhood Hits	236	Target Neighborhood Hits	212	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.222721 (rank : 154)
Query Neighborhood Hits	236	Target Neighborhood Hits	206	Shared Neighborhood Hits	65
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.222348 (rank : 155)
Query Neighborhood Hits	236	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF8_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.275649 (rank : 137)
Query Neighborhood Hits	236	Target Neighborhood Hits	622	Shared Neighborhood Hits	109
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.282887 (rank : 134)
Query Neighborhood Hits	236	Target Neighborhood Hits	618	Shared Neighborhood Hits	105
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SMRA3_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.184360 (rank : 180)
Query Neighborhood Hits	236	Target Neighborhood Hits	265	Shared Neighborhood Hits	80
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.174655 (rank : 186)
Query Neighborhood Hits	236	Target Neighborhood Hits	267	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SPRY4_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.397288 (rank : 110)
Query Neighborhood Hits	236	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.408776 (rank : 109)
Query Neighborhood Hits	236	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TOPRS_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.107007 (rank : 235)
Query Neighborhood Hits	236	Target Neighborhood Hits	286	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.109544 (rank : 233)
Query Neighborhood Hits	236	Target Neighborhood Hits	263	Shared Neighborhood Hits	49
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.104310 (rank : 237)
Query Neighborhood Hits	236	Target Neighborhood Hits	402	Shared Neighborhood Hits	71
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.106407 (rank : 236)
Query Neighborhood Hits	236	Target Neighborhood Hits	394	Shared Neighborhood Hits	72
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.087959 (rank : 252)
Query Neighborhood Hits	236	Target Neighborhood Hits	463	Shared Neighborhood Hits	85
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.093538 (rank : 245)
Query Neighborhood Hits	236	Target Neighborhood Hits	476	Shared Neighborhood Hits	87
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.118056 (rank : 225)
Query Neighborhood Hits	236	Target Neighborhood Hits	373	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.055646 (rank : 294)
Query Neighborhood Hits	236	Target Neighborhood Hits	338	Shared Neighborhood Hits	45
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.130092 (rank : 210)
Query Neighborhood Hits	236	Target Neighborhood Hits	396	Shared Neighborhood Hits	76
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.143769 (rank : 201)
Query Neighborhood Hits	236	Target Neighborhood Hits	355	Shared Neighborhood Hits	76
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF6_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.198109 (rank : 169)
Query Neighborhood Hits	236	Target Neighborhood Hits	267	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.205318 (rank : 166)
Query Neighborhood Hits	236	Target Neighborhood Hits	255	Shared Neighborhood Hits	77
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAF7_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.115215 (rank : 228)
Query Neighborhood Hits	236	Target Neighborhood Hits	482	Shared Neighborhood Hits	87
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.114280 (rank : 230)
Query Neighborhood Hits	236	Target Neighborhood Hits	470	Shared Neighborhood Hits	85
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAIP_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.124260 (rank : 220)
Query Neighborhood Hits	236	Target Neighborhood Hits	780	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.110188 (rank : 232)
Query Neighborhood Hits	236	Target Neighborhood Hits	745	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI16_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.452986 (rank : 88)
Query Neighborhood Hits	236	Target Neighborhood Hits	231	Shared Neighborhood Hits	91
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.421673 (rank : 106)
Query Neighborhood Hits	236	Target Neighborhood Hits	273	Shared Neighborhood Hits	97
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI42_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.285760 (rank : 133)
Query Neighborhood Hits	236	Target Neighborhood Hits	316	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI47_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.443263 (rank : 98)
Query Neighborhood Hits	236	Target Neighborhood Hits	295	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI62_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.622724 (rank : 47)
Query Neighborhood Hits	236	Target Neighborhood Hits	478	Shared Neighborhood Hits	111
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI65_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.538680 (rank : 57)
Query Neighborhood Hits	236	Target Neighborhood Hits	330	Shared Neighborhood Hits	106
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.529141 (rank : 61)
Query Neighborhood Hits	236	Target Neighborhood Hits	340	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

UB7I3_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.064285 (rank : 283)
Query Neighborhood Hits	236	Target Neighborhood Hits	136	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.079195 (rank : 262)
Query Neighborhood Hits	236	Target Neighborhood Hits	131	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UHRF1_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.154426 (rank : 191)
Query Neighborhood Hits	236	Target Neighborhood Hits	272	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.160270 (rank : 188)
Query Neighborhood Hits	236	Target Neighborhood Hits	278	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.196540 (rank : 171)
Query Neighborhood Hits	236	Target Neighborhood Hits	269	Shared Neighborhood Hits	85
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.191985 (rank : 174)
Query Neighborhood Hits	236	Target Neighborhood Hits	275	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZN179_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.426890 (rank : 105)
Query Neighborhood Hits	236	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN313_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.310488 (rank : 123)
Query Neighborhood Hits	236	Target Neighborhood Hits	264	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.321226 (rank : 120)
Query Neighborhood Hits	236	Target Neighborhood Hits	273	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

ZSWM2_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.069471 (rank : 277)
Query Neighborhood Hits	236	Target Neighborhood Hits	151	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

MEFV_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	236	Target Neighborhood Hits	236	Shared Neighborhood Hits	236
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_HUMAN
NC score	0.774427 (rank : 2)	θ value	8.35901e-139 (rank : 2)
Query Neighborhood Hits	236	Target Neighborhood Hits	431	Shared Neighborhood Hits	133
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI31_HUMAN
NC score	0.731904 (rank : 3)	θ value	2.13179e-17 (rank : 7)
Query Neighborhood Hits	236	Target Neighborhood Hits	299	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI15_HUMAN
NC score	0.727091 (rank : 4)	θ value	2.06002e-20 (rank : 5)
Query Neighborhood Hits	236	Target Neighborhood Hits	395	Shared Neighborhood Hits	115
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI10_HUMAN
NC score	0.721622 (rank : 5)	θ value	5.60996e-18 (rank : 6)
Query Neighborhood Hits	236	Target Neighborhood Hits	315	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI27_HUMAN
NC score	0.715674 (rank : 6)	θ value	1.33217e-27 (rank : 3)
Query Neighborhood Hits	236	Target Neighborhood Hits	273	Shared Neighborhood Hits	104
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.715291 (rank : 7)	θ value	3.87602e-27 (rank : 4)
Query Neighborhood Hits	236	Target Neighborhood Hits	261	Shared Neighborhood Hits	104
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI34_MOUSE
NC score	0.714986 (rank : 8)	θ value	1.09485e-13 (rank : 12)
Query Neighborhood Hits	236	Target Neighborhood Hits	332	Shared Neighborhood Hits	107
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI10_MOUSE
NC score	0.711567 (rank : 9)	θ value	3.18553e-13 (rank : 16)
Query Neighborhood Hits	236	Target Neighborhood Hits	285	Shared Neighborhood Hits	100
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI26_MOUSE
NC score	0.710982 (rank : 10)	θ value	1.52774e-15 (rank : 8)
Query Neighborhood Hits	236	Target Neighborhood Hits	339	Shared Neighborhood Hits	103
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI26_HUMAN
NC score	0.708730 (rank : 11)	θ value	2.28291e-11 (rank : 22)
Query Neighborhood Hits	236	Target Neighborhood Hits	335	Shared Neighborhood Hits	101
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRIM6_MOUSE
NC score	0.705724 (rank : 12)	θ value	1.86753e-13 (rank : 15)
Query Neighborhood Hits	236	Target Neighborhood Hits	451	Shared Neighborhood Hits	120
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM7_MOUSE
NC score	0.704588 (rank : 13)	θ value	1.09485e-13 (rank : 14)
Query Neighborhood Hits	236	Target Neighborhood Hits	358	Shared Neighborhood Hits	112
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI41_HUMAN
NC score	0.701531 (rank : 14)	θ value	8.67504e-11 (rank : 23)
Query Neighborhood Hits	236	Target Neighborhood Hits	349	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM5_HUMAN
NC score	0.699734 (rank : 15)	θ value	5.62301e-10 (rank : 24)
Query Neighborhood Hits	236	Target Neighborhood Hits	424	Shared Neighborhood Hits	115
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM7_HUMAN
NC score	0.698501 (rank : 16)	θ value	1.02475e-11 (rank : 20)
Query Neighborhood Hits	236	Target Neighborhood Hits	336	Shared Neighborhood Hits	109
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI43_HUMAN
NC score	0.698278 (rank : 17)	θ value	1.02475e-11 (rank : 19)
Query Neighborhood Hits	236	Target Neighborhood Hits	341	Shared Neighborhood Hits	105
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI17_HUMAN
NC score	0.696788 (rank : 18)	θ value	7.34386e-10 (rank : 26)
Query Neighborhood Hits	236	Target Neighborhood Hits	318	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRIM6_HUMAN
NC score	0.696338 (rank : 19)	θ value	1.63604e-09 (rank : 30)
Query Neighborhood Hits	236	Target Neighborhood Hits	412	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI12_MOUSE
NC score	0.696214 (rank : 20)	θ value	2.36244e-08 (rank : 38)
Query Neighborhood Hits	236	Target Neighborhood Hits	387	Shared Neighborhood Hits	109
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI34_HUMAN
NC score	0.695105 (rank : 21)	θ value	1.06045e-08 (rank : 33)
Query Neighborhood Hits	236	Target Neighborhood Hits	416	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI38_HUMAN
NC score	0.694996 (rank : 22)	θ value	8.38298e-14 (rank : 11)
Query Neighborhood Hits	236	Target Neighborhood Hits	373	Shared Neighborhood Hits	111
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRIM4_HUMAN
NC score	0.693817 (rank : 23)	θ value	2.13673e-09 (rank : 31)
Query Neighborhood Hits	236	Target Neighborhood Hits	321	Shared Neighborhood Hits	104
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI22_HUMAN
NC score	0.690961 (rank : 24)	θ value	6.87365e-08 (rank : 42)
Query Neighborhood Hits	236	Target Neighborhood Hits	396	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI17_MOUSE
NC score	0.689230 (rank : 25)	θ value	3.40345e-15 (rank : 9)
Query Neighborhood Hits	236	Target Neighborhood Hits	620	Shared Neighborhood Hits	122
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI52_HUMAN
NC score	0.687678 (rank : 26)	θ value	1.43324e-05 (rank : 48)
Query Neighborhood Hits	236	Target Neighborhood Hits	213	Shared Neighborhood Hits	90
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI49_HUMAN
NC score	0.687195 (rank : 27)	θ value	1.29631e-06 (rank : 46)
Query Neighborhood Hits	236	Target Neighborhood Hits	199	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI30_MOUSE
NC score	0.687078 (rank : 28)	θ value	4.92598e-06 (rank : 47)
Query Neighborhood Hits	236	Target Neighborhood Hits	434	Shared Neighborhood Hits	114
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI60_HUMAN
NC score	0.683758 (rank : 29)	θ value	1.33837e-11 (rank : 21)
Query Neighborhood Hits	236	Target Neighborhood Hits	357	Shared Neighborhood Hits	104
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI11_HUMAN
NC score	0.683550 (rank : 30)	θ value	2.69671e-12 (rank : 17)
Query Neighborhood Hits	236	Target Neighborhood Hits	316	Shared Neighborhood Hits	100
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
NC score	0.683078 (rank : 31)	θ value	7.34386e-10 (rank : 25)
Query Neighborhood Hits	236	Target Neighborhood Hits	329	Shared Neighborhood Hits	105
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI68_HUMAN
NC score	0.682259 (rank : 32)	θ value	1.38499e-08 (rank : 34)
Query Neighborhood Hits	236	Target Neighborhood Hits	267	Shared Neighborhood Hits	98
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI68_MOUSE
NC score	0.682030 (rank : 33)	θ value	7.34386e-10 (rank : 27)
Query Neighborhood Hits	236	Target Neighborhood Hits	356	Shared Neighborhood Hits	114
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI40_HUMAN
NC score	0.681286 (rank : 34)	θ value	4.76016e-09 (rank : 32)
Query Neighborhood Hits	236	Target Neighborhood Hits	279	Shared Neighborhood Hits	94
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

RO52_HUMAN
NC score	0.679302 (rank : 35)	θ value	1.02475e-11 (rank : 18)
Query Neighborhood Hits	236	Target Neighborhood Hits	419	Shared Neighborhood Hits	117
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI60_MOUSE
NC score	0.678932 (rank : 36)	θ value	2.36244e-08 (rank : 39)
Query Neighborhood Hits	236	Target Neighborhood Hits	240	Shared Neighborhood Hits	101
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

RO52_MOUSE
NC score	0.678634 (rank : 37)	θ value	1.25267e-09 (rank : 28)
Query Neighborhood Hits	236	Target Neighborhood Hits	360	Shared Neighborhood Hits	107
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI39_HUMAN
NC score	0.672192 (rank : 38)	θ value	9.90251e-15 (rank : 10)
Query Neighborhood Hits	236	Target Neighborhood Hits	693	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
NC score	0.672175 (rank : 39)	θ value	1.09485e-13 (rank : 13)
Query Neighborhood Hits	236	Target Neighborhood Hits	691	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI35_HUMAN
NC score	0.666720 (rank : 40)	θ value	1.80886e-08 (rank : 36)
Query Neighborhood Hits	236	Target Neighborhood Hits	382	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
NC score	0.657603 (rank : 41)	θ value	7.59969e-07 (rank : 45)
Query Neighborhood Hits	236	Target Neighborhood Hits	465	Shared Neighborhood Hits	110
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI50_MOUSE
NC score	0.650365 (rank : 42)	θ value	3.41135e-07 (rank : 43)
Query Neighborhood Hits	236	Target Neighborhood Hits	326	Shared Neighborhood Hits	110
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_HUMAN
NC score	0.639997 (rank : 43)	θ value	0.00035302 (rank : 57)
Query Neighborhood Hits	236	Target Neighborhood Hits	294	Shared Neighborhood Hits	104
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI74_HUMAN
NC score	0.635388 (rank : 44)	θ value	0.000786445 (rank : 61)
Query Neighborhood Hits	236	Target Neighborhood Hits	249	Shared Neighborhood Hits	103
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI73_HUMAN
NC score	0.634464 (rank : 45)	θ value	0.000461057 (rank : 58)
Query Neighborhood Hits	236	Target Neighborhood Hits	258	Shared Neighborhood Hits	103
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI62_HUMAN
NC score	0.629445 (rank : 46)	θ value	0.00298849 (rank : 68)
Query Neighborhood Hits	236	Target Neighborhood Hits	584	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
NC score	0.622724 (rank : 47)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	236	Target Neighborhood Hits	478	Shared Neighborhood Hits	111
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI48_HUMAN
NC score	0.614944 (rank : 48)	θ value	0.0736092 (rank : 93)
Query Neighborhood Hits	236	Target Neighborhood Hits	192	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI13_MOUSE
NC score	0.593784 (rank : 49)	θ value	0.00175202 (rank : 65)
Query Neighborhood Hits	236	Target Neighborhood Hits	282	Shared Neighborhood Hits	102
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
NC score	0.590091 (rank : 50)	θ value	0.0252991 (rank : 82)
Query Neighborhood Hits	236	Target Neighborhood Hits	274	Shared Neighborhood Hits	98
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI59_MOUSE
NC score	0.579593 (rank : 51)	θ value	0.00175202 (rank : 66)
Query Neighborhood Hits	236	Target Neighborhood Hits	292	Shared Neighborhood Hits	103
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.576543 (rank : 52)	θ value	0.00869519 (rank : 73)
Query Neighborhood Hits	236	Target Neighborhood Hits	307	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

RNF39_HUMAN
NC score	0.548556 (rank : 53)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	236	Target Neighborhood Hits	200	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI14_MOUSE
NC score	0.546052 (rank : 54)	θ value	0.0113563 (rank : 75)
Query Neighborhood Hits	236	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI14_HUMAN
NC score	0.539723 (rank : 55)	θ value	0.0252991 (rank : 83)
Query Neighborhood Hits	236	Target Neighborhood Hits	143	Shared Neighborhood Hits	92
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRIM8_MOUSE
NC score	0.539030 (rank : 56)	θ value	0.000121331 (rank : 53)
Query Neighborhood Hits	236	Target Neighborhood Hits	674	Shared Neighborhood Hits	128
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI65_HUMAN
NC score	0.538680 (rank : 57)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	236	Target Neighborhood Hits	330	Shared Neighborhood Hits	106
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM8_HUMAN
NC score	0.538301 (rank : 58)	θ value	5.44631e-05 (rank : 51)
Query Neighborhood Hits	236	Target Neighborhood Hits	650	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RFPL3_HUMAN
NC score	0.534234 (rank : 59)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	236	Target Neighborhood Hits	134	Shared Neighborhood Hits	71
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFPL1_HUMAN
NC score	0.529583 (rank : 60)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	236	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI65_MOUSE
NC score	0.529141 (rank : 61)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	236	Target Neighborhood Hits	340	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RFPL2_HUMAN
NC score	0.528756 (rank : 62)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	236	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

ERMAP_HUMAN
NC score	0.523381 (rank : 63)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	236	Target Neighborhood Hits	155	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI44_MOUSE
NC score	0.523360 (rank : 64)	θ value	0.00390308 (rank : 69)
Query Neighborhood Hits	236	Target Neighborhood Hits	327	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

BSPRY_HUMAN
NC score	0.516477 (rank : 65)	θ value	0.0148317 (rank : 77)
Query Neighborhood Hits	236	Target Neighborhood Hits	115	Shared Neighborhood Hits	70
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI63_MOUSE
NC score	0.516176 (rank : 66)	θ value	0.365318 (rank : 110)
Query Neighborhood Hits	236	Target Neighborhood Hits	240	Shared Neighborhood Hits	104
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI63_HUMAN
NC score	0.513944 (rank : 67)	θ value	0.0961366 (rank : 96)
Query Neighborhood Hits	236	Target Neighborhood Hits	298	Shared Neighborhood Hits	110
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI32_HUMAN
NC score	0.512785 (rank : 68)	θ value	0.000786445 (rank : 60)
Query Neighborhood Hits	236	Target Neighborhood Hits	264	Shared Neighborhood Hits	97
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI44_HUMAN
NC score	0.510842 (rank : 69)	θ value	0.0113563 (rank : 76)
Query Neighborhood Hits	236	Target Neighborhood Hits	393	Shared Neighborhood Hits	97
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI32_MOUSE
NC score	0.509973 (rank : 70)	θ value	0.00102713 (rank : 62)
Query Neighborhood Hits	236	Target Neighborhood Hits	271	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI55_HUMAN
NC score	0.506017 (rank : 71)	θ value	0.0563607 (rank : 89)
Query Neighborhood Hits	236	Target Neighborhood Hits	292	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

BSPRY_MOUSE
NC score	0.495640 (rank : 72)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	75
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI54_HUMAN
NC score	0.484213 (rank : 73)	θ value	0.0961366 (rank : 95)
Query Neighborhood Hits	236	Target Neighborhood Hits	209	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
NC score	0.483869 (rank : 74)	θ value	0.21417 (rank : 103)
Query Neighborhood Hits	236	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

ERMAP_MOUSE
NC score	0.481246 (rank : 75)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	236	Target Neighborhood Hits	231	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

TRI25_HUMAN
NC score	0.477295 (rank : 76)	θ value	0.0563607 (rank : 88)
Query Neighborhood Hits	236	Target Neighborhood Hits	472	Shared Neighborhood Hits	113
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI16_MOUSE
NC score	0.470942 (rank : 77)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	236	Target Neighborhood Hits	196	Shared Neighborhood Hits	93
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI37_HUMAN
NC score	0.470057 (rank : 78)	θ value	0.62314 (rank : 126)
Query Neighborhood Hits	236	Target Neighborhood Hits	307	Shared Neighborhood Hits	110
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.469956 (rank : 79)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	236	Target Neighborhood Hits	316	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI25_MOUSE
NC score	0.469310 (rank : 80)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	236	Target Neighborhood Hits	446	Shared Neighborhood Hits	115
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRIM3_MOUSE
NC score	0.469034 (rank : 81)	θ value	0.0736092 (rank : 94)
Query Neighborhood Hits	236	Target Neighborhood Hits	351	Shared Neighborhood Hits	107
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.462729 (rank : 82)	θ value	0.0961366 (rank : 97)
Query Neighborhood Hits	236	Target Neighborhood Hits	357	Shared Neighborhood Hits	106
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

BT1A1_MOUSE
NC score	0.458071 (rank : 83)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	236	Target Neighborhood Hits	252	Shared Neighborhood Hits	60
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

TRIM2_HUMAN
NC score	0.456327 (rank : 84)	θ value	0.0563607 (rank : 90)
Query Neighborhood Hits	236	Target Neighborhood Hits	330	Shared Neighborhood Hits	103
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

BT2A2_HUMAN
NC score	0.455906 (rank : 85)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	236	Target Neighborhood Hits	191	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRIM2_MOUSE
NC score	0.455114 (rank : 86)	θ value	0.0563607 (rank : 91)
Query Neighborhood Hits	236	Target Neighborhood Hits	331	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI18_HUMAN
NC score	0.454704 (rank : 87)	θ value	0.47712 (rank : 119)
Query Neighborhood Hits	236	Target Neighborhood Hits	307	Shared Neighborhood Hits	109
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI16_HUMAN
NC score	0.452986 (rank : 88)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	236	Target Neighborhood Hits	231	Shared Neighborhood Hits	91
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BT1A1_HUMAN
NC score	0.451374 (rank : 89)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	236	Target Neighborhood Hits	322	Shared Neighborhood Hits	61
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A3_HUMAN
NC score	0.450784 (rank : 90)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	236	Target Neighborhood Hits	233	Shared Neighborhood Hits	60
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT2A3_HUMAN
NC score	0.450538 (rank : 91)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	236	Target Neighborhood Hits	195	Shared Neighborhood Hits	56
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BTNL3_HUMAN
NC score	0.450036 (rank : 92)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	236	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRI29_MOUSE
NC score	0.449776 (rank : 93)	θ value	0.00035302 (rank : 55)
Query Neighborhood Hits	236	Target Neighborhood Hits	306	Shared Neighborhood Hits	100
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

BTNL9_HUMAN
NC score	0.449608 (rank : 94)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	236	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BT3A1_HUMAN
NC score	0.449142 (rank : 95)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	236	Target Neighborhood Hits	229	Shared Neighborhood Hits	59
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT2A1_HUMAN
NC score	0.447125 (rank : 96)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	236	Target Neighborhood Hits	185	Shared Neighborhood Hits	58
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

TRI18_MOUSE
NC score	0.443466 (rank : 97)	θ value	0.47712 (rank : 120)
Query Neighborhood Hits	236	Target Neighborhood Hits	292	Shared Neighborhood Hits	108
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI47_MOUSE
NC score	0.443263 (rank : 98)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	236	Target Neighborhood Hits	295	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM1_HUMAN
NC score	0.443170 (rank : 99)	θ value	0.0148317 (rank : 78)
Query Neighborhood Hits	236	Target Neighborhood Hits	345	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.439606 (rank : 100)	θ value	0.0148317 (rank : 79)
Query Neighborhood Hits	236	Target Neighborhood Hits	361	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI47_HUMAN
NC score	0.435671 (rank : 101)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	236	Target Neighborhood Hits	286	Shared Neighborhood Hits	100
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

BTNL8_HUMAN
NC score	0.434600 (rank : 102)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	236	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

TRI46_MOUSE
NC score	0.432888 (rank : 103)	θ value	0.00035302 (rank : 56)
Query Neighborhood Hits	236	Target Neighborhood Hits	287	Shared Neighborhood Hits	108
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.430219 (rank : 104)	θ value	0.00298849 (rank : 67)
Query Neighborhood Hits	236	Target Neighborhood Hits	291	Shared Neighborhood Hits	109
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

ZN179_HUMAN
NC score	0.426890 (rank : 105)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	236	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI29_HUMAN
NC score	0.421673 (rank : 106)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	236	Target Neighborhood Hits	273	Shared Neighborhood Hits	97
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI36_HUMAN
NC score	0.421608 (rank : 107)	θ value	2.44474e-05 (rank : 50)
Query Neighborhood Hits	236	Target Neighborhood Hits	282	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
NC score	0.412032 (rank : 108)	θ value	1.87187e-05 (rank : 49)
Query Neighborhood Hits	236	Target Neighborhood Hits	266	Shared Neighborhood Hits	108
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

SPRY4_MOUSE
NC score	0.408776 (rank : 109)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	236	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_HUMAN
NC score	0.397288 (rank : 110)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	236	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRIM9_HUMAN
NC score	0.359203 (rank : 111)	θ value	0.365318 (rank : 111)
Query Neighborhood Hits	236	Target Neighborhood Hits	294	Shared Neighborhood Hits	96
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
NC score	0.357692 (rank : 112)	θ value	0.365318 (rank : 112)
Query Neighborhood Hits	236	Target Neighborhood Hits	274	Shared Neighborhood Hits	97
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI56_MOUSE
NC score	0.355992 (rank : 113)	θ value	0.21417 (rank : 104)
Query Neighborhood Hits	236	Target Neighborhood Hits	255	Shared Neighborhood Hits	97
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI56_HUMAN
NC score	0.352942 (rank : 114)	θ value	0.47712 (rank : 121)
Query Neighborhood Hits	236	Target Neighborhood Hits	339	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

BFAR_HUMAN
NC score	0.342761 (rank : 115)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	236	Target Neighborhood Hits	222	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
NC score	0.335611 (rank : 116)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	236	Target Neighborhood Hits	232	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRCA1_MOUSE
NC score	0.333668 (rank : 117)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	236	Target Neighborhood Hits	436	Shared Neighborhood Hits	108
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRCA1_HUMAN
NC score	0.333350 (rank : 118)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	236	Target Neighborhood Hits	381	Shared Neighborhood Hits	95
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

RN168_HUMAN
NC score	0.325551 (rank : 119)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	236	Target Neighborhood Hits	370	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ZN313_MOUSE
NC score	0.321226 (rank : 120)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	236	Target Neighborhood Hits	273	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

ASC_MOUSE
NC score	0.319599 (rank : 121)	θ value	1.63604e-09 (rank : 29)
Query Neighborhood Hits	236	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

PEX10_HUMAN
NC score	0.314255 (rank : 122)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	236	Target Neighborhood Hits	255	Shared Neighborhood Hits	69
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

ZN313_HUMAN
NC score	0.310488 (rank : 123)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	236	Target Neighborhood Hits	264	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RN168_MOUSE
NC score	0.309787 (rank : 124)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	236	Target Neighborhood Hits	440	Shared Neighborhood Hits	101
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN166_HUMAN
NC score	0.304805 (rank : 125)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	236	Target Neighborhood Hits	240	Shared Neighborhood Hits	79
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN125_MOUSE
NC score	0.304585 (rank : 126)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	236	Target Neighborhood Hits	220	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

ASC_HUMAN
NC score	0.297944 (rank : 127)	θ value	1.80886e-08 (rank : 35)
Query Neighborhood Hits	236	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

RN125_HUMAN
NC score	0.294868 (rank : 128)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	236	Target Neighborhood Hits	230	Shared Neighborhood Hits	76
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI42_HUMAN
NC score	0.293675 (rank : 129)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	236	Target Neighborhood Hits	283	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

RN166_MOUSE
NC score	0.293610 (rank : 130)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	236	Target Neighborhood Hits	248	Shared Neighborhood Hits	79
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TIF1G_HUMAN
NC score	0.292476 (rank : 131)	θ value	0.00665767 (rank : 71)
Query Neighborhood Hits	236	Target Neighborhood Hits	410	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.289334 (rank : 132)	θ value	0.00665767 (rank : 72)
Query Neighborhood Hits	236	Target Neighborhood Hits	498	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI42_MOUSE
NC score	0.285760 (rank : 133)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	236	Target Neighborhood Hits	316	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

RNF8_MOUSE
NC score	0.282887 (rank : 134)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	236	Target Neighborhood Hits	618	Shared Neighborhood Hits	105
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RN183_HUMAN
NC score	0.278559 (rank : 135)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	236	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI45_HUMAN
NC score	0.277380 (rank : 136)	θ value	0.279714 (rank : 108)
Query Neighborhood Hits	236	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

RNF8_HUMAN
NC score	0.275649 (rank : 137)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	236	Target Neighborhood Hits	622	Shared Neighborhood Hits	109
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI45_MOUSE
NC score	0.272165 (rank : 138)	θ value	0.0252991 (rank : 84)
Query Neighborhood Hits	236	Target Neighborhood Hits	155	Shared Neighborhood Hits	82
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

RN169_HUMAN
NC score	0.262478 (rank : 139)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	236	Target Neighborhood Hits	203	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TIF1B_HUMAN
NC score	0.257744 (rank : 140)	θ value	0.813845 (rank : 131)
Query Neighborhood Hits	236	Target Neighborhood Hits	312	Shared Neighborhood Hits	88
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.253171 (rank : 141)	θ value	0.62314 (rank : 125)
Query Neighborhood Hits	236	Target Neighborhood Hits	276	Shared Neighborhood Hits	85
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

PML_HUMAN
NC score	0.249589 (rank : 142)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	236	Target Neighborhood Hits	248	Shared Neighborhood Hits	88
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RING1_HUMAN
NC score	0.248050 (rank : 143)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	236	Target Neighborhood Hits	219	Shared Neighborhood Hits	76
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RAG1_HUMAN
NC score	0.247706 (rank : 144)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	236	Target Neighborhood Hits	203	Shared Neighborhood Hits	62
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RING1_MOUSE
NC score	0.243631 (rank : 145)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	236	Target Neighborhood Hits	220	Shared Neighborhood Hits	78
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RAG1_MOUSE
NC score	0.238434 (rank : 146)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	236	Target Neighborhood Hits	189	Shared Neighborhood Hits	65
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TIF1A_HUMAN
NC score	0.237250 (rank : 147)	θ value	0.000270298 (rank : 54)
Query Neighborhood Hits	236	Target Neighborhood Hits	327	Shared Neighborhood Hits	81
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

RN183_MOUSE
NC score	0.234551 (rank : 148)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	236	Target Neighborhood Hits	119	Shared Neighborhood Hits	64
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
NC score	0.230342 (rank : 149)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	236	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.230317 (rank : 150)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	236	Target Neighborhood Hits	211	Shared Neighborhood Hits	66
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

NAL10_HUMAN
NC score	0.226271 (rank : 151)	θ value	3.08544e-08 (rank : 40)
Query Neighborhood Hits	236	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

RING2_MOUSE
NC score	0.224847 (rank : 152)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	236	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.224775 (rank : 153)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	236	Target Neighborhood Hits	201	Shared Neighborhood Hits	72
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RNF5_HUMAN
NC score	0.222721 (rank : 154)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	236	Target Neighborhood Hits	206	Shared Neighborhood Hits	65
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.222348 (rank : 155)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	236	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF41_MOUSE
NC score	0.221331 (rank : 156)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	236	Target Neighborhood Hits	224	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.221068 (rank : 157)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	236	Target Neighborhood Hits	226	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

PML_MOUSE
NC score	0.221028 (rank : 158)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	236	Target Neighborhood Hits	246	Shared Neighborhood Hits	86
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TIF1A_MOUSE
NC score	0.216170 (rank : 159)	θ value	0.000786445 (rank : 59)
Query Neighborhood Hits	236	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

CHFR_HUMAN
NC score	0.214545 (rank : 160)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	236	Target Neighborhood Hits	255	Shared Neighborhood Hits	75
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RNF4_HUMAN
NC score	0.213793 (rank : 161)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	236	Target Neighborhood Hits	212	Shared Neighborhood Hits	57
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RAD18_MOUSE
NC score	0.208945 (rank : 162)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	236	Target Neighborhood Hits	230	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

CHFR_MOUSE
NC score	0.208112 (rank : 163)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	236	Target Neighborhood Hits	264	Shared Neighborhood Hits	74
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RNF4_MOUSE
NC score	0.207568 (rank : 164)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	236	Target Neighborhood Hits	212	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

BIRC7_HUMAN
NC score	0.206357 (rank : 165)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	236	Target Neighborhood Hits	185	Shared Neighborhood Hits	78
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

TRAF6_MOUSE
NC score	0.205318 (rank : 166)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	236	Target Neighborhood Hits	255	Shared Neighborhood Hits	77
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

DTX3_MOUSE
NC score	0.199055 (rank : 167)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	236	Target Neighborhood Hits	202	Shared Neighborhood Hits	69
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RN146_HUMAN
NC score	0.198329 (rank : 168)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	236	Target Neighborhood Hits	162	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

TRAF6_HUMAN
NC score	0.198109 (rank : 169)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	236	Target Neighborhood Hits	267	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

RN146_MOUSE
NC score	0.196767 (rank : 170)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	236	Target Neighborhood Hits	161	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

UHRF2_HUMAN
NC score	0.196540 (rank : 171)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	236	Target Neighborhood Hits	269	Shared Neighborhood Hits	85
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

CIAS1_MOUSE
NC score	0.194135 (rank : 172)	θ value	5.26297e-08 (rank : 41)
Query Neighborhood Hits	236	Target Neighborhood Hits	67	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

CIAS1_HUMAN
NC score	0.192048 (rank : 173)	θ value	5.81887e-07 (rank : 44)
Query Neighborhood Hits	236	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

UHRF2_MOUSE
NC score	0.191985 (rank : 174)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	236	Target Neighborhood Hits	275	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

DTX3_HUMAN
NC score	0.191249 (rank : 175)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	236	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

NALP6_HUMAN
NC score	0.189378 (rank : 176)	θ value	0.00175202 (rank : 64)
Query Neighborhood Hits	236	Target Neighborhood Hits	52	Shared Neighborhood Hits	15
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NAL10_MOUSE
NC score	0.189148 (rank : 177)	θ value	0.0193708 (rank : 81)
Query Neighborhood Hits	236	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NAL12_HUMAN
NC score	0.186891 (rank : 178)	θ value	2.36244e-08 (rank : 37)
Query Neighborhood Hits	236	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

RAD18_HUMAN
NC score	0.186334 (rank : 179)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	236	Target Neighborhood Hits	284	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

SMRA3_HUMAN
NC score	0.184360 (rank : 180)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	236	Target Neighborhood Hits	265	Shared Neighborhood Hits	80
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

RN141_HUMAN
NC score	0.182035 (rank : 181)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	236	Target Neighborhood Hits	199	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.181290 (rank : 182)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	236	Target Neighborhood Hits	200	Shared Neighborhood Hits	73
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RFWD2_HUMAN
NC score	0.177174 (rank : 183)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	236	Target Neighborhood Hits	518	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.176820 (rank : 184)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	236	Target Neighborhood Hits	535	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

NALP6_MOUSE
NC score	0.176681 (rank : 185)	θ value	0.00134147 (rank : 63)
Query Neighborhood Hits	236	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

SMRA3_MOUSE
NC score	0.174655 (rank : 186)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	236	Target Neighborhood Hits	267	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

NALP4_HUMAN
NC score	0.171444 (rank : 187)	θ value	0.000121331 (rank : 52)
Query Neighborhood Hits	236	Target Neighborhood Hits	81	Shared Neighborhood Hits	14
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

UHRF1_MOUSE
NC score	0.160270 (rank : 188)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	236	Target Neighborhood Hits	278	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

PCGF6_MOUSE
NC score	0.158665 (rank : 189)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

CM007_MOUSE
NC score	0.154749 (rank : 190)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	236	Target Neighborhood Hits	416	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

UHRF1_HUMAN
NC score	0.154426 (rank : 191)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	236	Target Neighborhood Hits	272	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

NALP5_HUMAN
NC score	0.152588 (rank : 192)	θ value	0.00665767 (rank : 70)
Query Neighborhood Hits	236	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

R113B_HUMAN
NC score	0.151709 (rank : 193)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	236	Target Neighborhood Hits	165	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

LNX1_MOUSE
NC score	0.151385 (rank : 194)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	236	Target Neighborhood Hits	377	Shared Neighborhood Hits	77
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PCGF6_HUMAN
NC score	0.149467 (rank : 195)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	236	Target Neighborhood Hits	178	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

NALP2_HUMAN
NC score	0.149151 (rank : 196)	θ value	0.279714 (rank : 107)
Query Neighborhood Hits	236	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

LNX1_HUMAN
NC score	0.148018 (rank : 197)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	236	Target Neighborhood Hits	379	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_MOUSE
NC score	0.146232 (rank : 198)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	236	Target Neighborhood Hits	407	Shared Neighborhood Hits	83
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

NALP1_HUMAN
NC score	0.145886 (rank : 199)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	236	Target Neighborhood Hits	138	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

LNX2_HUMAN
NC score	0.143960 (rank : 200)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	236	Target Neighborhood Hits	389	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TRAF5_MOUSE
NC score	0.143769 (rank : 201)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	236	Target Neighborhood Hits	355	Shared Neighborhood Hits	76
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

NAL14_HUMAN
NC score	0.143237 (rank : 202)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	236	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP7_HUMAN
NC score	0.141454 (rank : 203)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	236	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

R113A_HUMAN
NC score	0.138490 (rank : 204)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	236	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RC3H1_MOUSE
NC score	0.133824 (rank : 205)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	236	Target Neighborhood Hits	244	Shared Neighborhood Hits	70
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

CM007_HUMAN
NC score	0.133515 (rank : 206)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	236	Target Neighborhood Hits	422	Shared Neighborhood Hits	66
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

PCGF4_MOUSE
NC score	0.132640 (rank : 207)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.131868 (rank : 208)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	236	Target Neighborhood Hits	161	Shared Neighborhood Hits	48
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

TRI66_MOUSE
NC score	0.131253 (rank : 209)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	236	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRAF5_HUMAN
NC score	0.130092 (rank : 210)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	236	Target Neighborhood Hits	396	Shared Neighborhood Hits	76
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

RC3H1_HUMAN
NC score	0.128485 (rank : 211)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	236	Target Neighborhood Hits	433	Shared Neighborhood Hits	74
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TRI66_HUMAN
NC score	0.128092 (rank : 212)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	236	Target Neighborhood Hits	479	Shared Neighborhood Hits	63
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RBBP6_MOUSE
NC score	0.127898 (rank : 213)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	236	Target Neighborhood Hits	1014	Shared Neighborhood Hits	104
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RN152_MOUSE
NC score	0.127158 (rank : 214)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	236	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN152_HUMAN
NC score	0.126843 (rank : 215)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	236	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

NAL11_HUMAN
NC score	0.126675 (rank : 216)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	236	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NAL13_HUMAN
NC score	0.126662 (rank : 217)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	236	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NHLC1_HUMAN
NC score	0.125677 (rank : 218)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	236	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
NC score	0.125584 (rank : 219)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	236	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRAIP_HUMAN
NC score	0.124260 (rank : 220)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	236	Target Neighborhood Hits	780	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

NALP5_MOUSE
NC score	0.123964 (rank : 221)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	236	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PCGF2_HUMAN
NC score	0.121020 (rank : 222)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	236	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.120831 (rank : 223)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	236	Target Neighborhood Hits	213	Shared Neighborhood Hits	48
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PZRN3_MOUSE
NC score	0.118243 (rank : 224)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	236	Target Neighborhood Hits	447	Shared Neighborhood Hits	84
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAF4_HUMAN
NC score	0.118056 (rank : 225)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	236	Target Neighborhood Hits	373	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

RBBP6_HUMAN
NC score	0.116676 (rank : 226)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	236	Target Neighborhood Hits	1135	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

PZRN3_HUMAN
NC score	0.116096 (rank : 227)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	236	Target Neighborhood Hits	461	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAF7_HUMAN
NC score	0.115215 (rank : 228)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	236	Target Neighborhood Hits	482	Shared Neighborhood Hits	87
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

PZRN4_HUMAN
NC score	0.114327 (rank : 229)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	236	Target Neighborhood Hits	438	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRAF7_MOUSE
NC score	0.114280 (rank : 230)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	236	Target Neighborhood Hits	470	Shared Neighborhood Hits	85
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

ARD1_MOUSE
NC score	0.110795 (rank : 231)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	236	Target Neighborhood Hits	573	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

TRAIP_MOUSE
NC score	0.110188 (rank : 232)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	236	Target Neighborhood Hits	745	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TOPRS_MOUSE
NC score	0.109544 (rank : 233)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	236	Target Neighborhood Hits	263	Shared Neighborhood Hits	49
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ARD1_HUMAN
NC score	0.109092 (rank : 234)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	236	Target Neighborhood Hits	621	Shared Neighborhood Hits	75
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

TOPRS_HUMAN
NC score	0.107007 (rank : 235)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	236	Target Neighborhood Hits	286	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_MOUSE
NC score	0.106407 (rank : 236)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	236	Target Neighborhood Hits	394	Shared Neighborhood Hits	72
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF2_HUMAN
NC score	0.104310 (rank : 237)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	236	Target Neighborhood Hits	402	Shared Neighborhood Hits	71
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

AMFR2_HUMAN
NC score	0.102521 (rank : 238)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	236	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

MAT1_HUMAN
NC score	0.101536 (rank : 239)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	236	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
NC score	0.100625 (rank : 240)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	236	Target Neighborhood Hits	217	Shared Neighborhood Hits	38
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

AMFR_MOUSE
NC score	0.099846 (rank : 241)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	236	Target Neighborhood Hits	208	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

RINI_HUMAN
NC score	0.098195 (rank : 242)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	236	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
NC score	0.096713 (rank : 243)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	236	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

BIRC8_HUMAN
NC score	0.094431 (rank : 244)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	236	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

TRAF3_MOUSE
NC score	0.093538 (rank : 245)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	236	Target Neighborhood Hits	476	Shared Neighborhood Hits	87
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

CBL_HUMAN
NC score	0.091993 (rank : 246)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	236	Target Neighborhood Hits	353	Shared Neighborhood Hits	69
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBLC_MOUSE
NC score	0.091327 (rank : 247)	θ value	0.47712 (rank : 113)
Query Neighborhood Hits	236	Target Neighborhood Hits	186	Shared Neighborhood Hits	49
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

MNAB_HUMAN
NC score	0.090818 (rank : 248)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	236	Target Neighborhood Hits	196	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

CBL_MOUSE
NC score	0.089532 (rank : 249)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	236	Target Neighborhood Hits	426	Shared Neighborhood Hits	67
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

MNAB_MOUSE
NC score	0.089193 (rank : 250)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	236	Target Neighborhood Hits	231	Shared Neighborhood Hits	68
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

BARD1_HUMAN
NC score	0.088921 (rank : 251)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	236	Target Neighborhood Hits	427	Shared Neighborhood Hits	55
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

TRAF3_HUMAN
NC score	0.087959 (rank : 252)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	236	Target Neighborhood Hits	463	Shared Neighborhood Hits	85
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

BARD1_MOUSE
NC score	0.087578 (rank : 253)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	236	Target Neighborhood Hits	411	Shared Neighborhood Hits	54
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CBLB_MOUSE
NC score	0.087173 (rank : 254)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	236	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.085600 (rank : 255)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	236	Target Neighborhood Hits	261	Shared Neighborhood Hits	61
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

FSD1L_MOUSE
NC score	0.084369 (rank : 256)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	236	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

CAR15_HUMAN
NC score	0.084297 (rank : 257)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	236	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

RNF32_HUMAN
NC score	0.084239 (rank : 258)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	236	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

CAR15_MOUSE
NC score	0.083943 (rank : 259)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	236	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CBLC_HUMAN
NC score	0.080968 (rank : 260)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	236	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

C2TA_MOUSE
NC score	0.079689 (rank : 261)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	236	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

UB7I3_MOUSE
NC score	0.079195 (rank : 262)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	236	Target Neighborhood Hits	131	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

CNOT4_HUMAN
NC score	0.078903 (rank : 263)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	236	Target Neighborhood Hits	207	Shared Neighborhood Hits	30
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CARD4_HUMAN
NC score	0.078895 (rank : 264)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	236	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

DTX3L_HUMAN
NC score	0.078175 (rank : 265)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	236	Target Neighborhood Hits	187	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RNF32_MOUSE
NC score	0.077843 (rank : 266)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	236	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_MOUSE
NC score	0.077444 (rank : 267)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	236	Target Neighborhood Hits	160	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

C2TA_HUMAN
NC score	0.077010 (rank : 268)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	236	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

RNF34_HUMAN
NC score	0.076483 (rank : 269)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	236	Target Neighborhood Hits	153	Shared Neighborhood Hits	33
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

CARD4_MOUSE
NC score	0.076378 (rank : 270)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	236	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CNOT4_MOUSE
NC score	0.076355 (rank : 271)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	236	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

BIRC3_HUMAN
NC score	0.074910 (rank : 272)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	236	Target Neighborhood Hits	133	Shared Neighborhood Hits	44
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

NEUL1_HUMAN
NC score	0.073373 (rank : 273)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	236	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

BIRC2_HUMAN
NC score	0.073312 (rank : 274)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	236	Target Neighborhood Hits	142	Shared Neighborhood Hits	49
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

RKHD1_HUMAN
NC score	0.073236 (rank : 275)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	28
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

BIRC2_MOUSE
NC score	0.069786 (rank : 276)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	236	Target Neighborhood Hits	137	Shared Neighborhood Hits	43
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

ZSWM2_HUMAN
NC score	0.069471 (rank : 277)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	236	Target Neighborhood Hits	151	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN123_MOUSE
NC score	0.069384 (rank : 278)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	236	Target Neighborhood Hits	174	Shared Neighborhood Hits	53
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_HUMAN
NC score	0.069145 (rank : 279)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	236	Target Neighborhood Hits	175	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

NEURL_MOUSE
NC score	0.067755 (rank : 280)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	236	Target Neighborhood Hits	106	Shared Neighborhood Hits	23
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

FSD1L_HUMAN
NC score	0.067578 (rank : 281)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	236	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

BRAP_HUMAN
NC score	0.064419 (rank : 282)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	236	Target Neighborhood Hits	560	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

UB7I3_HUMAN
NC score	0.064285 (rank : 283)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	236	Target Neighborhood Hits	136	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

SRRM2_HUMAN
NC score	0.064267 (rank : 284)	θ value	0.0113563 (rank : 74)
Query Neighborhood Hits	236	Target Neighborhood Hits	1296	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CP250_HUMAN
NC score	0.063362 (rank : 285)	θ value	0.0330416 (rank : 85)
Query Neighborhood Hits	236	Target Neighborhood Hits	1805	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

BRE1B_HUMAN
NC score	0.062238 (rank : 286)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	236	Target Neighborhood Hits	1040	Shared Neighborhood Hits	106
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
NC score	0.061777 (rank : 287)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	236	Target Neighborhood Hits	970	Shared Neighborhood Hits	101
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BIRC3_MOUSE
NC score	0.058995 (rank : 288)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	236	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

GCC2_MOUSE
NC score	0.058573 (rank : 289)	θ value	0.125558 (rank : 98)
Query Neighborhood Hits	236	Target Neighborhood Hits	1619	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

RFFL_HUMAN
NC score	0.057410 (rank : 290)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	236	Target Neighborhood Hits	175	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

MIB1_HUMAN
NC score	0.055926 (rank : 291)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	236	Target Neighborhood Hits	470	Shared Neighborhood Hits	54
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.055922 (rank : 292)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	236	Target Neighborhood Hits	471	Shared Neighborhood Hits	54
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RFFL_MOUSE
NC score	0.055843 (rank : 293)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	236	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

TRAF4_MOUSE
NC score	0.055646 (rank : 294)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	236	Target Neighborhood Hits	338	Shared Neighborhood Hits	45
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

MGRN1_MOUSE
NC score	0.054707 (rank : 295)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	236	Target Neighborhood Hits	149	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MGRN1_HUMAN
NC score	0.054467 (rank : 296)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	236	Target Neighborhood Hits	192	Shared Neighborhood Hits	40
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

BRE1A_HUMAN
NC score	0.054075 (rank : 297)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	236	Target Neighborhood Hits	1071	Shared Neighborhood Hits	95
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

GOGA4_MOUSE
NC score	0.053376 (rank : 298)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	236	Target Neighborhood Hits	1939	Shared Neighborhood Hits	118
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MKRN2_MOUSE
NC score	0.053255 (rank : 299)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	236	Target Neighborhood Hits	130	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

RNF26_HUMAN
NC score	0.053123 (rank : 300)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	236	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

BRAP_MOUSE
NC score	0.053071 (rank : 301)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	236	Target Neighborhood Hits	409	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

MKRN2_HUMAN
NC score	0.052524 (rank : 302)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	236	Target Neighborhood Hits	129	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

PJA1_HUMAN
NC score	0.052217 (rank : 303)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	236	Target Neighborhood Hits	159	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

BRE1A_MOUSE
NC score	0.052209 (rank : 304)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	236	Target Neighborhood Hits	1025	Shared Neighborhood Hits	91
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

GCC2_HUMAN
NC score	0.052161 (rank : 305)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	236	Target Neighborhood Hits	1558	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.052079 (rank : 306)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	236	Target Neighborhood Hits	1559	Shared Neighborhood Hits	96
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

LRSM1_HUMAN
NC score	0.051293 (rank : 307)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	236	Target Neighborhood Hits	1078	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

AZI1_MOUSE
NC score	0.051253 (rank : 308)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	236	Target Neighborhood Hits	990	Shared Neighborhood Hits	69
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

TARA_MOUSE
NC score	0.051248 (rank : 309)	θ value	1.06291 (rank : 141)
Query Neighborhood Hits	236	Target Neighborhood Hits	1133	Shared Neighborhood Hits	60
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GOGB1_HUMAN
NC score	0.050936 (rank : 310)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	236	Target Neighborhood Hits	2297	Shared Neighborhood Hits	123
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CP250_MOUSE
NC score	0.050744 (rank : 311)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	236	Target Neighborhood Hits	1583	Shared Neighborhood Hits	91
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

RNF19_HUMAN
NC score	0.050480 (rank : 312)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	236	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

IFT74_HUMAN
NC score	0.049573 (rank : 313)	θ value	0.0330416 (rank : 86)
Query Neighborhood Hits	236	Target Neighborhood Hits	949	Shared Neighborhood Hits	51
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CENPE_HUMAN
NC score	0.048839 (rank : 314)	θ value	0.813845 (rank : 129)
Query Neighborhood Hits	236	Target Neighborhood Hits	2060	Shared Neighborhood Hits	105
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

IFT74_MOUSE
NC score	0.048801 (rank : 315)	θ value	0.62314 (rank : 123)
Query Neighborhood Hits	236	Target Neighborhood Hits	939	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SRRM2_MOUSE
NC score	0.047841 (rank : 316)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	236	Target Neighborhood Hits	1470	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AZI1_HUMAN
NC score	0.047628 (rank : 317)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	236	Target Neighborhood Hits	1000	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CENPF_HUMAN
NC score	0.046471 (rank : 318)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	236	Target Neighborhood Hits	1932	Shared Neighborhood Hits	104
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

TARA_HUMAN
NC score	0.045470 (rank : 319)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	236	Target Neighborhood Hits	1626	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

EP15R_HUMAN
NC score	0.045465 (rank : 320)	θ value	0.0563607 (rank : 87)
Query Neighborhood Hits	236	Target Neighborhood Hits	1083	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

NIN_MOUSE
NC score	0.044332 (rank : 321)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	236	Target Neighborhood Hits	1376	Shared Neighborhood Hits	83
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

BSN_HUMAN
NC score	0.043397 (rank : 322)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	236	Target Neighborhood Hits	1537	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

EEA1_HUMAN
NC score	0.042905 (rank : 323)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	236	Target Neighborhood Hits	1796	Shared Neighborhood Hits	104
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RP1L1_HUMAN
NC score	0.040431 (rank : 324)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	236	Target Neighborhood Hits	1072	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

BSN_MOUSE
NC score	0.040146 (rank : 325)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	236	Target Neighborhood Hits	2057	Shared Neighborhood Hits	72
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GCC1_MOUSE
NC score	0.040129 (rank : 326)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	236	Target Neighborhood Hits	777	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

CCD21_MOUSE
NC score	0.039530 (rank : 327)	θ value	0.813845 (rank : 128)
Query Neighborhood Hits	236	Target Neighborhood Hits	1135	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

DMP1_MOUSE
NC score	0.039262 (rank : 328)	θ value	0.279714 (rank : 106)
Query Neighborhood Hits	236	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

SWP70_MOUSE
NC score	0.038179 (rank : 329)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	236	Target Neighborhood Hits	1097	Shared Neighborhood Hits	62
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

APC_MOUSE
NC score	0.037541 (rank : 330)	θ value	0.21417 (rank : 99)
Query Neighborhood Hits	236	Target Neighborhood Hits	441	Shared Neighborhood Hits	33
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CCD21_HUMAN
NC score	0.036796 (rank : 331)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	236	Target Neighborhood Hits	1228	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CNOT3_MOUSE
NC score	0.034592 (rank : 332)	θ value	0.62314 (rank : 122)
Query Neighborhood Hits	236	Target Neighborhood Hits	504	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CEP63_HUMAN
NC score	0.034378 (rank : 333)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	236	Target Neighborhood Hits	1005	Shared Neighborhood Hits	62
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

NPBL_MOUSE
NC score	0.033978 (rank : 334)	θ value	0.47712 (rank : 117)
Query Neighborhood Hits	236	Target Neighborhood Hits	1041	Shared Neighborhood Hits	43
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

IF2P_HUMAN
NC score	0.033842 (rank : 335)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	236	Target Neighborhood Hits	889	Shared Neighborhood Hits	53
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

TACC2_HUMAN
NC score	0.033666 (rank : 336)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	236	Target Neighborhood Hits	856	Shared Neighborhood Hits	49
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

MYH11_MOUSE
NC score	0.033621 (rank : 337)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	236	Target Neighborhood Hits	1777	Shared Neighborhood Hits	100
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MAP1B_MOUSE
NC score	0.033545 (rank : 338)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	236	Target Neighborhood Hits	977	Shared Neighborhood Hits	63
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CF010_HUMAN
NC score	0.033521 (rank : 339)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	236	Target Neighborhood Hits	329	Shared Neighborhood Hits	28
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

MYH11_HUMAN
NC score	0.033464 (rank : 340)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	236	Target Neighborhood Hits	1806	Shared Neighborhood Hits	106
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MDC1_MOUSE
NC score	0.033444 (rank : 341)	θ value	0.47712 (rank : 115)
Query Neighborhood Hits	236	Target Neighborhood Hits	998	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

HDAC5_HUMAN
NC score	0.033409 (rank : 342)	θ value	0.21417 (rank : 101)
Query Neighborhood Hits	236	Target Neighborhood Hits	353	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

TCOF_HUMAN
NC score	0.033063 (rank : 343)	θ value	1.06291 (rank : 142)
Query Neighborhood Hits	236	Target Neighborhood Hits	543	Shared Neighborhood Hits	32
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

LETM1_HUMAN
NC score	0.032743 (rank : 344)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	236	Target Neighborhood Hits	338	Shared Neighborhood Hits	27
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

NEUM_HUMAN
NC score	0.031498 (rank : 345)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	236	Target Neighborhood Hits	132	Shared Neighborhood Hits	13
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

STMN1_MOUSE
NC score	0.031426 (rank : 346)	θ value	0.62314 (rank : 124)
Query Neighborhood Hits	236	Target Neighborhood Hits	560	Shared Neighborhood Hits	36
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

CP135_MOUSE
NC score	0.030540 (rank : 347)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	236	Target Neighborhood Hits	1278	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DOT1L_HUMAN
NC score	0.030537 (rank : 348)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	236	Target Neighborhood Hits	660	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PRGC1_MOUSE
NC score	0.030407 (rank : 349)	θ value	0.47712 (rank : 118)
Query Neighborhood Hits	236	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

K0552_HUMAN
NC score	0.030218 (rank : 350)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	236	Target Neighborhood Hits	442	Shared Neighborhood Hits	35
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

NFH_HUMAN
NC score	0.030097 (rank : 351)	θ value	0.0736092 (rank : 92)
Query Neighborhood Hits	236	Target Neighborhood Hits	1242	Shared Neighborhood Hits	57
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TXND2_MOUSE
NC score	0.030028 (rank : 352)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	236	Target Neighborhood Hits	828	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

STMN1_HUMAN
NC score	0.029531 (rank : 353)	θ value	0.813845 (rank : 130)
Query Neighborhood Hits	236	Target Neighborhood Hits	554	Shared Neighborhood Hits	35
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

AFF4_MOUSE
NC score	0.028645 (rank : 354)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	236	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

SSF1_HUMAN
NC score	0.028548 (rank : 355)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	236	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQ55, Q9BW97, Q9H170	Gene names	PPAN, SSF1
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

CCD45_HUMAN
NC score	0.027748 (rank : 356)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	236	Target Neighborhood Hits	525	Shared Neighborhood Hits	37
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

AFF4_HUMAN
NC score	0.026763 (rank : 357)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	236	Target Neighborhood Hits	611	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

MEGF8_HUMAN
NC score	0.026351 (rank : 358)	θ value	0.21417 (rank : 102)
Query Neighborhood Hits	236	Target Neighborhood Hits	528	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

HDAC5_MOUSE
NC score	0.024918 (rank : 359)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	236	Target Neighborhood Hits	310	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

CTR9_MOUSE
NC score	0.024852 (rank : 360)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	236	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

APOE_MOUSE
NC score	0.024501 (rank : 361)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	236	Target Neighborhood Hits	319	Shared Neighborhood Hits	28
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

MEGF8_MOUSE
NC score	0.024452 (rank : 362)	θ value	0.47712 (rank : 116)
Query Neighborhood Hits	236	Target Neighborhood Hits	520	Shared Neighborhood Hits	10
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TXLNG_MOUSE
NC score	0.024277 (rank : 363)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	236	Target Neighborhood Hits	552	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

NFH_MOUSE
NC score	0.023823 (rank : 364)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	236	Target Neighborhood Hits	2247	Shared Neighborhood Hits	78
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LAMB2_HUMAN
NC score	0.023383 (rank : 365)	θ value	0.0193708 (rank : 80)
Query Neighborhood Hits	236	Target Neighborhood Hits	692	Shared Neighborhood Hits	26
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

FUT8_MOUSE
NC score	0.022594 (rank : 366)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	236	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

GATA5_HUMAN
NC score	0.022592 (rank : 367)	θ value	0.21417 (rank : 100)
Query Neighborhood Hits	236	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

PCLO_MOUSE
NC score	0.022375 (rank : 368)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	236	Target Neighborhood Hits	2275	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CK024_HUMAN
NC score	0.022112 (rank : 369)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	236	Target Neighborhood Hits	408	Shared Neighborhood Hits	18
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

3BP5_HUMAN
NC score	0.021986 (rank : 370)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	236	Target Neighborhood Hits	375	Shared Neighborhood Hits	27
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

K1543_HUMAN
NC score	0.021597 (rank : 371)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	236	Target Neighborhood Hits	435	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

ZAR1_HUMAN
NC score	0.021130 (rank : 372)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	236	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZC3H3_HUMAN
NC score	0.020804 (rank : 373)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	236	Target Neighborhood Hits	159	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

CCNB3_MOUSE
NC score	0.019885 (rank : 374)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	236	Target Neighborhood Hits	211	Shared Neighborhood Hits	15
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

SYBU_HUMAN
NC score	0.019785 (rank : 375)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	236	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

LAMB2_MOUSE
NC score	0.019557 (rank : 376)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	236	Target Neighborhood Hits	722	Shared Neighborhood Hits	29
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

CND1_HUMAN
NC score	0.019401 (rank : 377)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	236	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q15021, Q8N6U3	Gene names	NCAPD2, CAPD2, CNAP1, KIAA0159
Domain Architecture
Description	Condensin complex subunit 1 (Non-SMC condensin I complex subunit D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (XCAP-D2 homolog).

BYST_MOUSE
NC score	0.019376 (rank : 378)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	236	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O54825, Q3THF4, Q3UPY9, Q8VD68	Gene names	Bysl
Domain Architecture
Description	Bystin.

ANR11_HUMAN
NC score	0.018243 (rank : 379)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	236	Target Neighborhood Hits	1289	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

AFF1_MOUSE
NC score	0.018122 (rank : 380)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	236	Target Neighborhood Hits	351	Shared Neighborhood Hits	20
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ARS2_MOUSE
NC score	0.016817 (rank : 381)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	236	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

SET1A_HUMAN
NC score	0.016349 (rank : 382)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	236	Target Neighborhood Hits	690	Shared Neighborhood Hits	27
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CLCN1_HUMAN
NC score	0.016120 (rank : 383)	θ value	0.47712 (rank : 114)
Query Neighborhood Hits	236	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLGN_MOUSE
NC score	0.015779 (rank : 384)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	236	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

SFRS4_MOUSE
NC score	0.014700 (rank : 385)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	236	Target Neighborhood Hits	406	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SLK_MOUSE
NC score	0.014314 (rank : 386)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	236	Target Neighborhood Hits	1798	Shared Neighborhood Hits	75
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

HBP1_HUMAN
NC score	0.013682 (rank : 387)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	236	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

PKHA5_HUMAN
NC score	0.013544 (rank : 388)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	236	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CSKI1_MOUSE
NC score	0.013374 (rank : 389)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	236	Target Neighborhood Hits	1031	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_MOUSE
NC score	0.013275 (rank : 390)	θ value	0.279714 (rank : 105)
Query Neighborhood Hits	236	Target Neighborhood Hits	812	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

SLK_HUMAN
NC score	0.013060 (rank : 391)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	236	Target Neighborhood Hits	1775	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

EPN2_HUMAN
NC score	0.012918 (rank : 392)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	236	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

STK10_HUMAN
NC score	0.012819 (rank : 393)	θ value	0.365318 (rank : 109)
Query Neighborhood Hits	236	Target Neighborhood Hits	1921	Shared Neighborhood Hits	74
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_MOUSE
NC score	0.012775 (rank : 394)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	236	Target Neighborhood Hits	2132	Shared Neighborhood Hits	76
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

IRX1_MOUSE
NC score	0.011878 (rank : 395)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	236	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	P81068, O55120, Q9JLL6	Gene names	Irx1, Irxa1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

IRX1_HUMAN
NC score	0.011863 (rank : 396)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	236	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

NACA_HUMAN
NC score	0.011742 (rank : 397)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	236	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q13765, Q53A18, Q53G46	Gene names	NACA
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (Hom s 2.02).

HM2L1_HUMAN
NC score	0.011682 (rank : 398)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	236	Target Neighborhood Hits	130	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

FBX34_MOUSE
NC score	0.011323 (rank : 399)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	236	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

TCEA2_MOUSE
NC score	0.011242 (rank : 400)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	236	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QVN7, O08667	Gene names	Tcea2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Protein S-II-T1) (Transcription elongation factor TFIIS.l).

TERT_HUMAN
NC score	0.011178 (rank : 401)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	236	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	O14746, O14783, Q2XS35, Q8N6C3	Gene names	TERT, EST2, TCS1, TRT
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (HEST2) (Telomerase-associated protein 2) (TP2).

KHK_MOUSE
NC score	0.010704 (rank : 402)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	236	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P97328, Q91WU8	Gene names	Khk
Domain Architecture
Description	Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase).

RFTN1_MOUSE
NC score	0.010329 (rank : 403)	θ value	6.88961 (rank : 214)
Query Neighborhood Hits	236	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A0D4, Q3U654, Q3U8P6, Q80US1	Gene names	Rftn1, Kiaa0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein).

NAB1_MOUSE
NC score	0.010064 (rank : 404)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	236	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q61122	Gene names	Nab1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1).

IRX2_MOUSE
NC score	0.009327 (rank : 405)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	236	Target Neighborhood Hits	264	Shared Neighborhood Hits	5
SwissProt Accessions	P81066, O55121, Q9ERN1	Gene names	Irx2, Irxa2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

PHC1_HUMAN
NC score	0.009324 (rank : 406)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	236	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

MIER1_MOUSE
NC score	0.009017 (rank : 407)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	236	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

HUWE1_HUMAN
NC score	0.007335 (rank : 408)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	236	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

DDX21_HUMAN
NC score	0.007183 (rank : 409)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	236	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

AP3B2_HUMAN
NC score	0.007024 (rank : 410)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	236	Target Neighborhood Hits	246	Shared Neighborhood Hits	10
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

SSPO_MOUSE
NC score	0.006691 (rank : 411)	θ value	1.06291 (rank : 140)
Query Neighborhood Hits	236	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TENX_HUMAN
NC score	0.005321 (rank : 412)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	236	Target Neighborhood Hits	789	Shared Neighborhood Hits	21
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

CNGB1_HUMAN
NC score	0.003959 (rank : 413)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	236	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

NEO1_HUMAN
NC score	0.002579 (rank : 414)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	236	Target Neighborhood Hits	530	Shared Neighborhood Hits	15
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NOTC4_HUMAN
NC score	0.002209 (rank : 415)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	236	Target Neighborhood Hits	905	Shared Neighborhood Hits	11
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ROBO1_MOUSE
NC score	0.001019 (rank : 416)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	236	Target Neighborhood Hits	559	Shared Neighborhood Hits	13
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO1_HUMAN
NC score	0.000730 (rank : 417)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	236	Target Neighborhood Hits	529	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

PRP4B_MOUSE
NC score	-0.000326 (rank : 418)	θ value	6.88961 (rank : 213)
Query Neighborhood Hits	236	Target Neighborhood Hits	1040	Shared Neighborhood Hits	24
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SPEG_MOUSE
NC score	-0.001129 (rank : 419)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	236	Target Neighborhood Hits	1959	Shared Neighborhood Hits	40
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PLMN_MOUSE
NC score	-0.002605 (rank : 420)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	236	Target Neighborhood Hits	208	Shared Neighborhood Hits	2
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

GAK_MOUSE
NC score	-0.003223 (rank : 421)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	236	Target Neighborhood Hits	964	Shared Neighborhood Hits	13
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

ZBT20_HUMAN
NC score	-0.005270 (rank : 422)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	236	Target Neighborhood Hits	835	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

ZNF35_HUMAN
NC score	-0.006855 (rank : 423)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	236	Target Neighborhood Hits	761	Shared Neighborhood Hits	5
SwissProt Accessions	P13682, Q96D01	Gene names	ZNF35
Domain Architecture	No domain graphic available
Description	Zinc finger protein 35 (Zinc finger protein HF.10).

ZKSC1_MOUSE
NC score	-0.006990 (rank : 424)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	236	Target Neighborhood Hits	755	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGS3, Q7TS88, Q8BJ55, Q9CRN6	Gene names	Zkscan1
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1.