Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : HUWE1_HUMAN

For an explanation of this page, click here

HUWE1_HUMAN
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HUWE1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	443	Target Neighborhood Hits	443	Shared Neighborhood Hits	443
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	0 (rank : 2)	NC score	0.989016 (rank : 2)
Query Neighborhood Hits	443	Target Neighborhood Hits	406	Shared Neighborhood Hits	300
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

NED4L_HUMAN
θ value	2.81514e-94 (rank : 3)	NC score	0.808996 (rank : 23)
Query Neighborhood Hits	443	Target Neighborhood Hits	238	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	2.81514e-94 (rank : 4)	NC score	0.810169 (rank : 22)
Query Neighborhood Hits	443	Target Neighborhood Hits	231	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_HUMAN
θ value	4.06505e-93 (rank : 5)	NC score	0.823868 (rank : 21)
Query Neighborhood Hits	443	Target Neighborhood Hits	214	Shared Neighborhood Hits	38
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

ITCH_MOUSE
θ value	5.30912e-93 (rank : 6)	NC score	0.874064 (rank : 10)
Query Neighborhood Hits	443	Target Neighborhood Hits	127	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

NEDD4_MOUSE
θ value	2.63489e-92 (rank : 7)	NC score	0.830141 (rank : 20)
Query Neighborhood Hits	443	Target Neighborhood Hits	212	Shared Neighborhood Hits	41
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

ITCH_HUMAN
θ value	3.44127e-92 (rank : 8)	NC score	0.867007 (rank : 15)
Query Neighborhood Hits	443	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

SMUF1_MOUSE
θ value	4.96919e-91 (rank : 9)	NC score	0.878185 (rank : 4)
Query Neighborhood Hits	443	Target Neighborhood Hits	142	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
θ value	4.96919e-91 (rank : 10)	NC score	0.876754 (rank : 8)
Query Neighborhood Hits	443	Target Neighborhood Hits	142	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_HUMAN
θ value	2.46618e-90 (rank : 11)	NC score	0.881173 (rank : 3)
Query Neighborhood Hits	443	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

WWP1_HUMAN
θ value	7.93343e-89 (rank : 12)	NC score	0.863292 (rank : 17)
Query Neighborhood Hits	443	Target Neighborhood Hits	262	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP1_MOUSE
θ value	7.93343e-89 (rank : 13)	NC score	0.866793 (rank : 16)
Query Neighborhood Hits	443	Target Neighborhood Hits	138	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_HUMAN
θ value	1.14559e-87 (rank : 14)	NC score	0.867338 (rank : 14)
Query Neighborhood Hits	443	Target Neighborhood Hits	177	Shared Neighborhood Hits	50
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	1.14559e-87 (rank : 15)	NC score	0.868436 (rank : 13)
Query Neighborhood Hits	443	Target Neighborhood Hits	118	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

K0317_MOUSE
θ value	1.84601e-53 (rank : 16)	NC score	0.877116 (rank : 7)
Query Neighborhood Hits	443	Target Neighborhood Hits	43	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_HUMAN
θ value	2.41096e-53 (rank : 17)	NC score	0.877158 (rank : 6)
Query Neighborhood Hits	443	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

UBE3A_HUMAN
θ value	2.66562e-52 (rank : 18)	NC score	0.873705 (rank : 11)
Query Neighborhood Hits	443	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

HECD2_HUMAN
θ value	7.75577e-52 (rank : 19)	NC score	0.875007 (rank : 9)
Query Neighborhood Hits	443	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	7.75577e-52 (rank : 20)	NC score	0.877258 (rank : 5)
Query Neighborhood Hits	443	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_MOUSE
θ value	6.14528e-49 (rank : 21)	NC score	0.868769 (rank : 12)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	1.51363e-47 (rank : 22)	NC score	0.862853 (rank : 18)
Query Neighborhood Hits	443	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	9.81109e-47 (rank : 23)	NC score	0.861519 (rank : 19)
Query Neighborhood Hits	443	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

HERC3_HUMAN
θ value	5.21438e-40 (rank : 24)	NC score	0.721890 (rank : 27)
Query Neighborhood Hits	443	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC2_MOUSE
θ value	1.52067e-31 (rank : 25)	NC score	0.625012 (rank : 31)
Query Neighborhood Hits	443	Target Neighborhood Hits	167	Shared Neighborhood Hits	41
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
θ value	5.77852e-31 (rank : 26)	NC score	0.620820 (rank : 32)
Query Neighborhood Hits	443	Target Neighborhood Hits	163	Shared Neighborhood Hits	41
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

TRIPC_HUMAN
θ value	4.14116e-29 (rank : 27)	NC score	0.794785 (rank : 24)
Query Neighborhood Hits	443	Target Neighborhood Hits	319	Shared Neighborhood Hits	69
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HERC5_HUMAN
θ value	3.87602e-27 (rank : 28)	NC score	0.718453 (rank : 28)
Query Neighborhood Hits	443	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

EDD1_HUMAN
θ value	1.62847e-25 (rank : 29)	NC score	0.698365 (rank : 30)
Query Neighborhood Hits	443	Target Neighborhood Hits	170	Shared Neighborhood Hits	55
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	1.62847e-25 (rank : 30)	NC score	0.699896 (rank : 29)
Query Neighborhood Hits	443	Target Neighborhood Hits	167	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HECD3_MOUSE
θ value	4.73814e-25 (rank : 31)	NC score	0.728370 (rank : 25)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
θ value	1.37858e-24 (rank : 32)	NC score	0.724450 (rank : 26)
Query Neighborhood Hits	443	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD1_HUMAN
θ value	2.06002e-20 (rank : 33)	NC score	0.556768 (rank : 33)
Query Neighborhood Hits	443	Target Neighborhood Hits	371	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

LEO1_HUMAN
θ value	6.43352e-06 (rank : 34)	NC score	0.109238 (rank : 60)
Query Neighborhood Hits	443	Target Neighborhood Hits	958	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NFH_MOUSE
θ value	6.43352e-06 (rank : 35)	NC score	0.060850 (rank : 152)
Query Neighborhood Hits	443	Target Neighborhood Hits	2247	Shared Neighborhood Hits	207
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LEO1_MOUSE
θ value	8.40245e-06 (rank : 36)	NC score	0.106025 (rank : 61)
Query Neighborhood Hits	443	Target Neighborhood Hits	946	Shared Neighborhood Hits	119
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TXND2_HUMAN
θ value	0.00020696 (rank : 37)	NC score	0.098686 (rank : 65)
Query Neighborhood Hits	443	Target Neighborhood Hits	793	Shared Neighborhood Hits	113
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

AKA12_HUMAN
θ value	0.000602161 (rank : 38)	NC score	0.115667 (rank : 59)
Query Neighborhood Hits	443	Target Neighborhood Hits	825	Shared Neighborhood Hits	127
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ETV3_MOUSE
θ value	0.00175202 (rank : 39)	NC score	0.039540 (rank : 243)
Query Neighborhood Hits	443	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

TCAL5_HUMAN
θ value	0.00228821 (rank : 40)	NC score	0.069027 (rank : 116)
Query Neighborhood Hits	443	Target Neighborhood Hits	806	Shared Neighborhood Hits	95
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

IWS1_MOUSE
θ value	0.00390308 (rank : 41)	NC score	0.091264 (rank : 72)
Query Neighborhood Hits	443	Target Neighborhood Hits	1258	Shared Neighborhood Hits	154
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RTN4_MOUSE
θ value	0.00390308 (rank : 42)	NC score	0.068272 (rank : 119)
Query Neighborhood Hits	443	Target Neighborhood Hits	341	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

ASPP1_MOUSE
θ value	0.00509761 (rank : 43)	NC score	0.037256 (rank : 253)
Query Neighborhood Hits	443	Target Neighborhood Hits	1244	Shared Neighborhood Hits	103
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MYO9B_HUMAN
θ value	0.00509761 (rank : 44)	NC score	0.025512 (rank : 317)
Query Neighborhood Hits	443	Target Neighborhood Hits	641	Shared Neighborhood Hits	73
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RTN4_HUMAN
θ value	0.00509761 (rank : 45)	NC score	0.078063 (rank : 103)
Query Neighborhood Hits	443	Target Neighborhood Hits	357	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TXND2_MOUSE
θ value	0.00509761 (rank : 46)	NC score	0.086526 (rank : 84)
Query Neighborhood Hits	443	Target Neighborhood Hits	828	Shared Neighborhood Hits	99
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

BSCL2_HUMAN
θ value	0.00665767 (rank : 47)	NC score	0.101893 (rank : 63)
Query Neighborhood Hits	443	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

ZFY1_MOUSE
θ value	0.00665767 (rank : 48)	NC score	0.005895 (rank : 497)
Query Neighborhood Hits	443	Target Neighborhood Hits	790	Shared Neighborhood Hits	33
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

TXLNB_HUMAN
θ value	0.00869519 (rank : 49)	NC score	0.035169 (rank : 265)
Query Neighborhood Hits	443	Target Neighborhood Hits	912	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

NCOR2_HUMAN
θ value	0.0113563 (rank : 50)	NC score	0.067697 (rank : 120)
Query Neighborhood Hits	443	Target Neighborhood Hits	870	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NSBP1_MOUSE
θ value	0.0113563 (rank : 51)	NC score	0.102568 (rank : 62)
Query Neighborhood Hits	443	Target Neighborhood Hits	681	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

BRD8_MOUSE
θ value	0.0148317 (rank : 52)	NC score	0.075053 (rank : 104)
Query Neighborhood Hits	443	Target Neighborhood Hits	422	Shared Neighborhood Hits	57
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

MATR3_MOUSE
θ value	0.0148317 (rank : 53)	NC score	0.079039 (rank : 101)
Query Neighborhood Hits	443	Target Neighborhood Hits	321	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

NIPBL_HUMAN
θ value	0.0148317 (rank : 54)	NC score	0.061740 (rank : 148)
Query Neighborhood Hits	443	Target Neighborhood Hits	1311	Shared Neighborhood Hits	146
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MAGE1_HUMAN
θ value	0.0193708 (rank : 55)	NC score	0.064979 (rank : 132)
Query Neighborhood Hits	443	Target Neighborhood Hits	1389	Shared Neighborhood Hits	138
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MDC1_HUMAN
θ value	0.0193708 (rank : 56)	NC score	0.074083 (rank : 108)
Query Neighborhood Hits	443	Target Neighborhood Hits	1446	Shared Neighborhood Hits	159
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MUC1_HUMAN
θ value	0.0193708 (rank : 57)	NC score	0.042165 (rank : 232)
Query Neighborhood Hits	443	Target Neighborhood Hits	975	Shared Neighborhood Hits	87
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CC47_MOUSE
θ value	0.0252991 (rank : 58)	NC score	0.066557 (rank : 125)
Query Neighborhood Hits	443	Target Neighborhood Hits	245	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

ERIC1_HUMAN
θ value	0.0252991 (rank : 59)	NC score	0.087930 (rank : 82)
Query Neighborhood Hits	443	Target Neighborhood Hits	364	Shared Neighborhood Hits	59
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

IWS1_HUMAN
θ value	0.0252991 (rank : 60)	NC score	0.086193 (rank : 86)
Query Neighborhood Hits	443	Target Neighborhood Hits	1241	Shared Neighborhood Hits	149
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PGCA_HUMAN
θ value	0.0252991 (rank : 61)	NC score	0.025626 (rank : 315)
Query Neighborhood Hits	443	Target Neighborhood Hits	821	Shared Neighborhood Hits	68
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

RPGR_HUMAN
θ value	0.0252991 (rank : 62)	NC score	0.119948 (rank : 58)
Query Neighborhood Hits	443	Target Neighborhood Hits	279	Shared Neighborhood Hits	43
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

BRD8_HUMAN
θ value	0.0330416 (rank : 63)	NC score	0.060681 (rank : 154)
Query Neighborhood Hits	443	Target Neighborhood Hits	292	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

NACAM_MOUSE
θ value	0.0330416 (rank : 64)	NC score	0.081685 (rank : 97)
Query Neighborhood Hits	443	Target Neighborhood Hits	1866	Shared Neighborhood Hits	175
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PEG3_MOUSE
θ value	0.0330416 (rank : 65)	NC score	0.016169 (rank : 393)
Query Neighborhood Hits	443	Target Neighborhood Hits	1101	Shared Neighborhood Hits	86
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

REV1_MOUSE
θ value	0.0330416 (rank : 66)	NC score	0.062091 (rank : 144)
Query Neighborhood Hits	443	Target Neighborhood Hits	67	Shared Neighborhood Hits	14
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

TF2AY_MOUSE
θ value	0.0330416 (rank : 67)	NC score	0.067672 (rank : 121)
Query Neighborhood Hits	443	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4I4, Q99PM2, Q9DAF4	Gene names	Gtf2a1lf, Alf
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

TP53B_HUMAN
θ value	0.0330416 (rank : 68)	NC score	0.080330 (rank : 98)
Query Neighborhood Hits	443	Target Neighborhood Hits	413	Shared Neighborhood Hits	79
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AKAP2_HUMAN
θ value	0.0431538 (rank : 69)	NC score	0.039767 (rank : 242)
Query Neighborhood Hits	443	Target Neighborhood Hits	507	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

RGS3_MOUSE
θ value	0.0431538 (rank : 70)	NC score	0.046916 (rank : 224)
Query Neighborhood Hits	443	Target Neighborhood Hits	1621	Shared Neighborhood Hits	134
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SEC63_HUMAN
θ value	0.0431538 (rank : 71)	NC score	0.053838 (rank : 191)
Query Neighborhood Hits	443	Target Neighborhood Hits	586	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

BPAEA_HUMAN
θ value	0.0563607 (rank : 72)	NC score	0.027751 (rank : 306)
Query Neighborhood Hits	443	Target Neighborhood Hits	1369	Shared Neighborhood Hits	69
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DMXL2_HUMAN
θ value	0.0563607 (rank : 73)	NC score	0.028247 (rank : 301)
Query Neighborhood Hits	443	Target Neighborhood Hits	374	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

DSPP_HUMAN
θ value	0.0563607 (rank : 74)	NC score	0.090397 (rank : 76)
Query Neighborhood Hits	443	Target Neighborhood Hits	645	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PRG4_HUMAN
θ value	0.0563607 (rank : 75)	NC score	0.083755 (rank : 89)
Query Neighborhood Hits	443	Target Neighborhood Hits	764	Shared Neighborhood Hits	127
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ATX2_MOUSE
θ value	0.0736092 (rank : 76)	NC score	0.061239 (rank : 149)
Query Neighborhood Hits	443	Target Neighborhood Hits	445	Shared Neighborhood Hits	63
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BRCA1_MOUSE
θ value	0.0736092 (rank : 77)	NC score	0.036611 (rank : 257)
Query Neighborhood Hits	443	Target Neighborhood Hits	436	Shared Neighborhood Hits	31
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

OSBL8_HUMAN
θ value	0.0736092 (rank : 78)	NC score	0.038170 (rank : 250)
Query Neighborhood Hits	443	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

TARA_HUMAN
θ value	0.0736092 (rank : 79)	NC score	0.059210 (rank : 159)
Query Neighborhood Hits	443	Target Neighborhood Hits	1626	Shared Neighborhood Hits	140
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ASPH_HUMAN
θ value	0.0961366 (rank : 80)	NC score	0.071867 (rank : 113)
Query Neighborhood Hits	443	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

CN155_HUMAN
θ value	0.0961366 (rank : 81)	NC score	0.095130 (rank : 67)
Query Neighborhood Hits	443	Target Neighborhood Hits	385	Shared Neighborhood Hits	72
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

EVI2B_MOUSE
θ value	0.0961366 (rank : 82)	NC score	0.046490 (rank : 226)
Query Neighborhood Hits	443	Target Neighborhood Hits	87	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

K1683_HUMAN
θ value	0.0961366 (rank : 83)	NC score	0.052112 (rank : 200)
Query Neighborhood Hits	443	Target Neighborhood Hits	240	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

NU214_HUMAN
θ value	0.0961366 (rank : 84)	NC score	0.079701 (rank : 100)
Query Neighborhood Hits	443	Target Neighborhood Hits	657	Shared Neighborhood Hits	83
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ZKSC1_HUMAN
θ value	0.0961366 (rank : 85)	NC score	0.002243 (rank : 525)
Query Neighborhood Hits	443	Target Neighborhood Hits	949	Shared Neighborhood Hits	52
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

ZN750_MOUSE
θ value	0.0961366 (rank : 86)	NC score	0.055114 (rank : 181)
Query Neighborhood Hits	443	Target Neighborhood Hits	346	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ADDA_MOUSE
θ value	0.125558 (rank : 87)	NC score	0.055156 (rank : 180)
Query Neighborhood Hits	443	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

ARHG3_MOUSE
θ value	0.125558 (rank : 88)	NC score	0.025417 (rank : 318)
Query Neighborhood Hits	443	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

DGKZ_HUMAN
θ value	0.125558 (rank : 89)	NC score	0.019843 (rank : 357)
Query Neighborhood Hits	443	Target Neighborhood Hits	551	Shared Neighborhood Hits	17
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

SON_HUMAN
θ value	0.125558 (rank : 90)	NC score	0.047511 (rank : 221)
Query Neighborhood Hits	443	Target Neighborhood Hits	1568	Shared Neighborhood Hits	131
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TGON2_HUMAN
θ value	0.125558 (rank : 91)	NC score	0.090504 (rank : 75)
Query Neighborhood Hits	443	Target Neighborhood Hits	1037	Shared Neighborhood Hits	137
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ZN628_MOUSE
θ value	0.125558 (rank : 92)	NC score	0.000171 (rank : 541)
Query Neighborhood Hits	443	Target Neighborhood Hits	815	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

CQ028_MOUSE
θ value	0.163984 (rank : 93)	NC score	0.049038 (rank : 214)
Query Neighborhood Hits	443	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

FBX34_MOUSE
θ value	0.163984 (rank : 94)	NC score	0.047123 (rank : 223)
Query Neighborhood Hits	443	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

HCFC1_MOUSE
θ value	0.163984 (rank : 95)	NC score	0.041589 (rank : 236)
Query Neighborhood Hits	443	Target Neighborhood Hits	348	Shared Neighborhood Hits	50
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MATR3_HUMAN
θ value	0.163984 (rank : 96)	NC score	0.064806 (rank : 135)
Query Neighborhood Hits	443	Target Neighborhood Hits	325	Shared Neighborhood Hits	51
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NIN_MOUSE
θ value	0.163984 (rank : 97)	NC score	0.021418 (rank : 347)
Query Neighborhood Hits	443	Target Neighborhood Hits	1376	Shared Neighborhood Hits	72
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NPM_MOUSE
θ value	0.163984 (rank : 98)	NC score	0.039361 (rank : 244)
Query Neighborhood Hits	443	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q61937	Gene names	Npm1
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

PERP_MOUSE
θ value	0.163984 (rank : 99)	NC score	0.057789 (rank : 166)
Query Neighborhood Hits	443	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JK95, Q9JI77	Gene names	Perp, Krtcap1
Domain Architecture	No domain graphic available
Description	p53 apoptosis effector related to PMP-22 (Keratinocytes-associated protein 1) (KCP-1).

SEC63_MOUSE
θ value	0.163984 (rank : 100)	NC score	0.049471 (rank : 213)
Query Neighborhood Hits	443	Target Neighborhood Hits	601	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SET1A_HUMAN
θ value	0.163984 (rank : 101)	NC score	0.074959 (rank : 105)
Query Neighborhood Hits	443	Target Neighborhood Hits	690	Shared Neighborhood Hits	116
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

AZI1_HUMAN
θ value	0.21417 (rank : 102)	NC score	0.023670 (rank : 328)
Query Neighborhood Hits	443	Target Neighborhood Hits	1000	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

DCP1A_HUMAN
θ value	0.21417 (rank : 103)	NC score	0.048091 (rank : 218)
Query Neighborhood Hits	443	Target Neighborhood Hits	228	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

GOGB1_HUMAN
θ value	0.21417 (rank : 104)	NC score	0.021434 (rank : 346)
Query Neighborhood Hits	443	Target Neighborhood Hits	2297	Shared Neighborhood Hits	125
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HCFC1_HUMAN
θ value	0.21417 (rank : 105)	NC score	0.042464 (rank : 231)
Query Neighborhood Hits	443	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MUC13_MOUSE
θ value	0.21417 (rank : 106)	NC score	0.072557 (rank : 110)
Query Neighborhood Hits	443	Target Neighborhood Hits	447	Shared Neighborhood Hits	63
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SGP50_MOUSE
θ value	0.21417 (rank : 107)	NC score	0.090256 (rank : 77)
Query Neighborhood Hits	443	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q02596	Gene names	Glycam1
Domain Architecture
Description	Sulfated 50 kDa glycoprotein precursor (SGP50) (Endothelial ligand FOR L-selectin) (Glycosylation-dependent cell adhesion molecule 1) (GlyCAM-1) (MC26).

E41L3_MOUSE
θ value	0.279714 (rank : 108)	NC score	0.020737 (rank : 353)
Query Neighborhood Hits	443	Target Neighborhood Hits	250	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

MUC1_MOUSE
θ value	0.279714 (rank : 109)	NC score	0.084092 (rank : 88)
Query Neighborhood Hits	443	Target Neighborhood Hits	388	Shared Neighborhood Hits	80
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

RAG2_MOUSE
θ value	0.279714 (rank : 110)	NC score	0.047479 (rank : 222)
Query Neighborhood Hits	443	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P21784	Gene names	Rag2, Rag-2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

VPS72_HUMAN
θ value	0.279714 (rank : 111)	NC score	0.063295 (rank : 141)
Query Neighborhood Hits	443	Target Neighborhood Hits	274	Shared Neighborhood Hits	34
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	0.279714 (rank : 112)	NC score	0.065913 (rank : 127)
Query Neighborhood Hits	443	Target Neighborhood Hits	286	Shared Neighborhood Hits	37
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ZCC2_HUMAN
θ value	0.279714 (rank : 113)	NC score	0.034142 (rank : 271)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

MAST1_MOUSE
θ value	0.365318 (rank : 114)	NC score	0.000833 (rank : 537)
Query Neighborhood Hits	443	Target Neighborhood Hits	1123	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NALP5_MOUSE
θ value	0.365318 (rank : 115)	NC score	0.030688 (rank : 285)
Query Neighborhood Hits	443	Target Neighborhood Hits	560	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NEK1_MOUSE
θ value	0.365318 (rank : 116)	NC score	0.003884 (rank : 508)
Query Neighborhood Hits	443	Target Neighborhood Hits	1311	Shared Neighborhood Hits	78
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

OGFR_MOUSE
θ value	0.365318 (rank : 117)	NC score	0.051443 (rank : 203)
Query Neighborhood Hits	443	Target Neighborhood Hits	584	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

REV1_HUMAN
θ value	0.365318 (rank : 118)	NC score	0.050559 (rank : 209)
Query Neighborhood Hits	443	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

SSBP4_HUMAN
θ value	0.365318 (rank : 119)	NC score	0.016181 (rank : 392)
Query Neighborhood Hits	443	Target Neighborhood Hits	753	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

BSCL2_MOUSE
θ value	0.47712 (rank : 120)	NC score	0.064152 (rank : 139)
Query Neighborhood Hits	443	Target Neighborhood Hits	94	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

E2F4_HUMAN
θ value	0.47712 (rank : 121)	NC score	0.035437 (rank : 264)
Query Neighborhood Hits	443	Target Neighborhood Hits	188	Shared Neighborhood Hits	23
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

INCE_HUMAN
θ value	0.47712 (rank : 122)	NC score	0.031566 (rank : 278)
Query Neighborhood Hits	443	Target Neighborhood Hits	978	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

NPBL_MOUSE
θ value	0.47712 (rank : 123)	NC score	0.058162 (rank : 163)
Query Neighborhood Hits	443	Target Neighborhood Hits	1041	Shared Neighborhood Hits	119
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TP53B_MOUSE
θ value	0.47712 (rank : 124)	NC score	0.071424 (rank : 115)
Query Neighborhood Hits	443	Target Neighborhood Hits	644	Shared Neighborhood Hits	95
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZN509_MOUSE
θ value	0.47712 (rank : 125)	NC score	0.000361 (rank : 540)
Query Neighborhood Hits	443	Target Neighborhood Hits	990	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

BPTF_HUMAN
θ value	0.62314 (rank : 126)	NC score	0.052602 (rank : 197)
Query Neighborhood Hits	443	Target Neighborhood Hits	786	Shared Neighborhood Hits	120
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DCP1A_MOUSE
θ value	0.62314 (rank : 127)	NC score	0.036323 (rank : 261)
Query Neighborhood Hits	443	Target Neighborhood Hits	103	Shared Neighborhood Hits	19
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

F10A5_HUMAN
θ value	0.62314 (rank : 128)	NC score	0.036587 (rank : 258)
Query Neighborhood Hits	443	Target Neighborhood Hits	277	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

K0141_MOUSE
θ value	0.62314 (rank : 129)	NC score	0.032900 (rank : 274)
Query Neighborhood Hits	443	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DCV6, Q6A0B8	Gene names	Kiaa0141
Domain Architecture
Description	Protein KIAA0141.

NASP_HUMAN
θ value	0.62314 (rank : 130)	NC score	0.071618 (rank : 114)
Query Neighborhood Hits	443	Target Neighborhood Hits	709	Shared Neighborhood Hits	104
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

POLI_HUMAN
θ value	0.62314 (rank : 131)	NC score	0.040367 (rank : 241)
Query Neighborhood Hits	443	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

POLI_MOUSE
θ value	0.62314 (rank : 132)	NC score	0.040970 (rank : 240)
Query Neighborhood Hits	443	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

RBM25_HUMAN
θ value	0.62314 (rank : 133)	NC score	0.041702 (rank : 235)
Query Neighborhood Hits	443	Target Neighborhood Hits	682	Shared Neighborhood Hits	70
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SF3B1_HUMAN
θ value	0.62314 (rank : 134)	NC score	0.030698 (rank : 284)
Query Neighborhood Hits	443	Target Neighborhood Hits	341	Shared Neighborhood Hits	31
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SRCA_MOUSE
θ value	0.62314 (rank : 135)	NC score	0.045509 (rank : 227)
Query Neighborhood Hits	443	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

STAR8_HUMAN
θ value	0.62314 (rank : 136)	NC score	0.016138 (rank : 394)
Query Neighborhood Hits	443	Target Neighborhood Hits	216	Shared Neighborhood Hits	24
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAT6_HUMAN
θ value	0.62314 (rank : 137)	NC score	0.012851 (rank : 425)
Query Neighborhood Hits	443	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

TGON1_MOUSE
θ value	0.62314 (rank : 138)	NC score	0.055567 (rank : 176)
Query Neighborhood Hits	443	Target Neighborhood Hits	243	Shared Neighborhood Hits	55
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

BPA1_MOUSE
θ value	0.813845 (rank : 139)	NC score	0.022309 (rank : 338)
Query Neighborhood Hits	443	Target Neighborhood Hits	1477	Shared Neighborhood Hits	85
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	0.813845 (rank : 140)	NC score	0.021805 (rank : 344)
Query Neighborhood Hits	443	Target Neighborhood Hits	1480	Shared Neighborhood Hits	77
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAMKV_HUMAN
θ value	0.813845 (rank : 141)	NC score	0.005361 (rank : 501)
Query Neighborhood Hits	443	Target Neighborhood Hits	1084	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CIC_HUMAN
θ value	0.813845 (rank : 142)	NC score	0.031041 (rank : 281)
Query Neighborhood Hits	443	Target Neighborhood Hits	992	Shared Neighborhood Hits	94
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DMP1_HUMAN
θ value	0.813845 (rank : 143)	NC score	0.095939 (rank : 66)
Query Neighborhood Hits	443	Target Neighborhood Hits	491	Shared Neighborhood Hits	105
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DTX2_HUMAN
θ value	0.813845 (rank : 144)	NC score	0.027936 (rank : 304)
Query Neighborhood Hits	443	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

EMSY_MOUSE
θ value	0.813845 (rank : 145)	NC score	0.041532 (rank : 237)
Query Neighborhood Hits	443	Target Neighborhood Hits	294	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

F10A1_HUMAN
θ value	0.813845 (rank : 146)	NC score	0.036399 (rank : 260)
Query Neighborhood Hits	443	Target Neighborhood Hits	312	Shared Neighborhood Hits	37
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

GP112_HUMAN
θ value	0.813845 (rank : 147)	NC score	0.026464 (rank : 312)
Query Neighborhood Hits	443	Target Neighborhood Hits	441	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

NF2L3_HUMAN
θ value	0.813845 (rank : 148)	NC score	0.024741 (rank : 322)
Query Neighborhood Hits	443	Target Neighborhood Hits	150	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NGEF_HUMAN
θ value	0.813845 (rank : 149)	NC score	0.016967 (rank : 384)
Query Neighborhood Hits	443	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PCLO_HUMAN
θ value	0.813845 (rank : 150)	NC score	0.089930 (rank : 79)
Query Neighborhood Hits	443	Target Neighborhood Hits	2046	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PTPRJ_MOUSE
θ value	0.813845 (rank : 151)	NC score	0.010563 (rank : 448)
Query Neighborhood Hits	443	Target Neighborhood Hits	188	Shared Neighborhood Hits	12
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

ZXDA_HUMAN
θ value	0.813845 (rank : 152)	NC score	-0.001218 (rank : 548)
Query Neighborhood Hits	443	Target Neighborhood Hits	750	Shared Neighborhood Hits	25
SwissProt Accessions	P98168, Q9UJP7	Gene names	ZXDA
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDA.

ANLN_MOUSE
θ value	1.06291 (rank : 153)	NC score	0.032645 (rank : 275)
Query Neighborhood Hits	443	Target Neighborhood Hits	297	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

BMP3_HUMAN
θ value	1.06291 (rank : 154)	NC score	0.008631 (rank : 469)
Query Neighborhood Hits	443	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	P12645	Gene names	BMP3
Domain Architecture
Description	Bone morphogenetic protein 3 precursor (BMP-3) (Osteogenin) (BMP-3A).

BSN_HUMAN
θ value	1.06291 (rank : 155)	NC score	0.047654 (rank : 220)
Query Neighborhood Hits	443	Target Neighborhood Hits	1537	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ELF4_MOUSE
θ value	1.06291 (rank : 156)	NC score	0.022346 (rank : 337)
Query Neighborhood Hits	443	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

FANCJ_HUMAN
θ value	1.06291 (rank : 157)	NC score	0.021957 (rank : 342)
Query Neighborhood Hits	443	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

HLX1_MOUSE
θ value	1.06291 (rank : 158)	NC score	0.009521 (rank : 460)
Query Neighborhood Hits	443	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	Q61670	Gene names	Hlx1, Hlx
Domain Architecture
Description	Homeobox protein HLX1.

MAML2_HUMAN
θ value	1.06291 (rank : 159)	NC score	0.028880 (rank : 296)
Query Neighborhood Hits	443	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MAP1A_HUMAN
θ value	1.06291 (rank : 160)	NC score	0.047929 (rank : 219)
Query Neighborhood Hits	443	Target Neighborhood Hits	1626	Shared Neighborhood Hits	152
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PODXL_HUMAN
θ value	1.06291 (rank : 161)	NC score	0.059830 (rank : 156)
Query Neighborhood Hits	443	Target Neighborhood Hits	191	Shared Neighborhood Hits	42
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

TF2AY_HUMAN
θ value	1.06291 (rank : 162)	NC score	0.046773 (rank : 225)
Query Neighborhood Hits	443	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UNN4	Gene names	GTF2A1LF, ALF
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

TITIN_HUMAN
θ value	1.06291 (rank : 163)	NC score	0.012384 (rank : 433)
Query Neighborhood Hits	443	Target Neighborhood Hits	2923	Shared Neighborhood Hits	163
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TMF1_HUMAN
θ value	1.06291 (rank : 164)	NC score	0.021124 (rank : 350)
Query Neighborhood Hits	443	Target Neighborhood Hits	987	Shared Neighborhood Hits	67
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TPR_HUMAN
θ value	1.06291 (rank : 165)	NC score	0.020532 (rank : 355)
Query Neighborhood Hits	443	Target Neighborhood Hits	1921	Shared Neighborhood Hits	135
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TTC1_HUMAN
θ value	1.06291 (rank : 166)	NC score	0.025405 (rank : 319)
Query Neighborhood Hits	443	Target Neighborhood Hits	417	Shared Neighborhood Hits	40
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

UACA_HUMAN
θ value	1.06291 (rank : 167)	NC score	0.014191 (rank : 411)
Query Neighborhood Hits	443	Target Neighborhood Hits	1622	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AKAP4_HUMAN
θ value	1.38821 (rank : 168)	NC score	0.018823 (rank : 367)
Query Neighborhood Hits	443	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

ALMS1_MOUSE
θ value	1.38821 (rank : 169)	NC score	0.020928 (rank : 351)
Query Neighborhood Hits	443	Target Neighborhood Hits	181	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ATX2_HUMAN
θ value	1.38821 (rank : 170)	NC score	0.055031 (rank : 182)
Query Neighborhood Hits	443	Target Neighborhood Hits	375	Shared Neighborhood Hits	50
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CK024_MOUSE
θ value	1.38821 (rank : 171)	NC score	0.065195 (rank : 130)
Query Neighborhood Hits	443	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

FOXC1_HUMAN
θ value	1.38821 (rank : 172)	NC score	0.008530 (rank : 471)
Query Neighborhood Hits	443	Target Neighborhood Hits	208	Shared Neighborhood Hits	30
SwissProt Accessions	Q12948, Q86UP7, Q9BYM1, Q9NUE5, Q9UDD0, Q9UP06	Gene names	FOXC1, FKHL7, FREAC3
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3).

GMPR1_HUMAN
θ value	1.38821 (rank : 173)	NC score	0.018790 (rank : 368)
Query Neighborhood Hits	443	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P36959, Q96HQ6	Gene names	GMPR, GMPR1
Domain Architecture
Description	GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1).

GP73_MOUSE
θ value	1.38821 (rank : 174)	NC score	0.038297 (rank : 249)
Query Neighborhood Hits	443	Target Neighborhood Hits	506	Shared Neighborhood Hits	53
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GRIPE_MOUSE
θ value	1.38821 (rank : 175)	NC score	0.023759 (rank : 327)
Query Neighborhood Hits	443	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

ITPR1_HUMAN
θ value	1.38821 (rank : 176)	NC score	0.008763 (rank : 468)
Query Neighborhood Hits	443	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

LIPA3_HUMAN
θ value	1.38821 (rank : 177)	NC score	0.015526 (rank : 401)
Query Neighborhood Hits	443	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPA3_MOUSE
θ value	1.38821 (rank : 178)	NC score	0.017153 (rank : 382)
Query Neighborhood Hits	443	Target Neighborhood Hits	636	Shared Neighborhood Hits	49
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MMRN2_HUMAN
θ value	1.38821 (rank : 179)	NC score	0.024586 (rank : 325)
Query Neighborhood Hits	443	Target Neighborhood Hits	400	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

PSMD2_MOUSE
θ value	1.38821 (rank : 180)	NC score	0.016071 (rank : 397)
Query Neighborhood Hits	443	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

PTN13_MOUSE
θ value	1.38821 (rank : 181)	NC score	0.010062 (rank : 455)
Query Neighborhood Hits	443	Target Neighborhood Hits	426	Shared Neighborhood Hits	27
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

TCAL3_HUMAN
θ value	1.38821 (rank : 182)	NC score	0.050575 (rank : 208)
Query Neighborhood Hits	443	Target Neighborhood Hits	274	Shared Neighborhood Hits	42
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TDRD5_HUMAN
θ value	1.38821 (rank : 183)	NC score	0.031372 (rank : 279)
Query Neighborhood Hits	443	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

CEP35_HUMAN
θ value	1.81305 (rank : 184)	NC score	0.033793 (rank : 273)
Query Neighborhood Hits	443	Target Neighborhood Hits	811	Shared Neighborhood Hits	80
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CJ118_MOUSE
θ value	1.81305 (rank : 185)	NC score	0.012888 (rank : 424)
Query Neighborhood Hits	443	Target Neighborhood Hits	1132	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CQ028_HUMAN
θ value	1.81305 (rank : 186)	NC score	0.038071 (rank : 251)
Query Neighborhood Hits	443	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

ESPL1_HUMAN
θ value	1.81305 (rank : 187)	NC score	0.019002 (rank : 365)
Query Neighborhood Hits	443	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

GAB1_HUMAN
θ value	1.81305 (rank : 188)	NC score	0.023788 (rank : 326)
Query Neighborhood Hits	443	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

LAMA2_MOUSE
θ value	1.81305 (rank : 189)	NC score	0.006113 (rank : 493)
Query Neighborhood Hits	443	Target Neighborhood Hits	1198	Shared Neighborhood Hits	56
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LATS2_HUMAN
θ value	1.81305 (rank : 190)	NC score	0.003133 (rank : 515)
Query Neighborhood Hits	443	Target Neighborhood Hits	884	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

LATS2_MOUSE
θ value	1.81305 (rank : 191)	NC score	0.002514 (rank : 523)
Query Neighborhood Hits	443	Target Neighborhood Hits	879	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

LRRF1_MOUSE
θ value	1.81305 (rank : 192)	NC score	0.039266 (rank : 245)
Query Neighborhood Hits	443	Target Neighborhood Hits	440	Shared Neighborhood Hits	55
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

MAP1B_MOUSE
θ value	1.81305 (rank : 193)	NC score	0.065075 (rank : 131)
Query Neighborhood Hits	443	Target Neighborhood Hits	977	Shared Neighborhood Hits	139
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MTMR3_MOUSE
θ value	1.81305 (rank : 194)	NC score	0.007730 (rank : 482)
Query Neighborhood Hits	443	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

MYST3_MOUSE
θ value	1.81305 (rank : 195)	NC score	0.041989 (rank : 234)
Query Neighborhood Hits	443	Target Neighborhood Hits	688	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NUPL_MOUSE
θ value	1.81305 (rank : 196)	NC score	0.019236 (rank : 361)
Query Neighborhood Hits	443	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

OXR1_MOUSE
θ value	1.81305 (rank : 197)	NC score	0.043017 (rank : 230)
Query Neighborhood Hits	443	Target Neighborhood Hits	516	Shared Neighborhood Hits	84
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PACN2_MOUSE
θ value	1.81305 (rank : 198)	NC score	0.014822 (rank : 408)
Query Neighborhood Hits	443	Target Neighborhood Hits	382	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PCLO_MOUSE
θ value	1.81305 (rank : 199)	NC score	0.081989 (rank : 96)
Query Neighborhood Hits	443	Target Neighborhood Hits	2275	Shared Neighborhood Hits	181
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDE1C_MOUSE
θ value	1.81305 (rank : 200)	NC score	0.009791 (rank : 459)
Query Neighborhood Hits	443	Target Neighborhood Hits	161	Shared Neighborhood Hits	27
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

RAD18_MOUSE
θ value	1.81305 (rank : 201)	NC score	0.019782 (rank : 358)
Query Neighborhood Hits	443	Target Neighborhood Hits	230	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RHBD3_MOUSE
θ value	1.81305 (rank : 202)	NC score	0.034176 (rank : 270)
Query Neighborhood Hits	443	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BP97, Q3U0Y4, Q5SUT5, Q5SUT6, Q5SUT7	Gene names	Rhbdd3
Domain Architecture	No domain graphic available
Description	Rhomboid domain-containing protein 3.

RPTN_MOUSE
θ value	1.81305 (rank : 203)	NC score	0.030811 (rank : 283)
Query Neighborhood Hits	443	Target Neighborhood Hits	650	Shared Neighborhood Hits	62
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SAS10_MOUSE
θ value	1.81305 (rank : 204)	NC score	0.037169 (rank : 254)
Query Neighborhood Hits	443	Target Neighborhood Hits	81	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

SF3B1_MOUSE
θ value	1.81305 (rank : 205)	NC score	0.027959 (rank : 303)
Query Neighborhood Hits	443	Target Neighborhood Hits	352	Shared Neighborhood Hits	31
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SMRC2_MOUSE
θ value	1.81305 (rank : 206)	NC score	0.036286 (rank : 262)
Query Neighborhood Hits	443	Target Neighborhood Hits	487	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SSH2_HUMAN
θ value	1.81305 (rank : 207)	NC score	0.008979 (rank : 466)
Query Neighborhood Hits	443	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SUHW1_HUMAN
θ value	1.81305 (rank : 208)	NC score	0.002521 (rank : 522)
Query Neighborhood Hits	443	Target Neighborhood Hits	648	Shared Neighborhood Hits	20
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

UBP5_MOUSE
θ value	1.81305 (rank : 209)	NC score	0.022195 (rank : 341)
Query Neighborhood Hits	443	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

Z297B_MOUSE
θ value	1.81305 (rank : 210)	NC score	0.001351 (rank : 534)
Query Neighborhood Hits	443	Target Neighborhood Hits	806	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DAI4	Gene names	Znf297b, Kiaa0414, Zfp297b
Domain Architecture
Description	Zinc finger protein 297B.

ZC11A_MOUSE
θ value	1.81305 (rank : 211)	NC score	0.031961 (rank : 277)
Query Neighborhood Hits	443	Target Neighborhood Hits	216	Shared Neighborhood Hits	34
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

CD34_MOUSE
θ value	2.36792 (rank : 212)	NC score	0.019207 (rank : 362)
Query Neighborhood Hits	443	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	Q64314, Q62550, Q62551	Gene names	Cd34
Domain Architecture
Description	Hematopoietic progenitor cell antigen CD34 precursor.

CHD9_HUMAN
θ value	2.36792 (rank : 213)	NC score	0.012422 (rank : 432)
Query Neighborhood Hits	443	Target Neighborhood Hits	343	Shared Neighborhood Hits	55
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CUTL1_MOUSE
θ value	2.36792 (rank : 214)	NC score	0.020132 (rank : 356)
Query Neighborhood Hits	443	Target Neighborhood Hits	1620	Shared Neighborhood Hits	112
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DNMBP_HUMAN
θ value	2.36792 (rank : 215)	NC score	0.014994 (rank : 407)
Query Neighborhood Hits	443	Target Neighborhood Hits	413	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

EP15R_MOUSE
θ value	2.36792 (rank : 216)	NC score	0.017187 (rank : 380)
Query Neighborhood Hits	443	Target Neighborhood Hits	1135	Shared Neighborhood Hits	80
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

GP124_MOUSE
θ value	2.36792 (rank : 217)	NC score	0.003283 (rank : 514)
Query Neighborhood Hits	443	Target Neighborhood Hits	423	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

IC1_MOUSE
θ value	2.36792 (rank : 218)	NC score	0.004942 (rank : 503)
Query Neighborhood Hits	443	Target Neighborhood Hits	164	Shared Neighborhood Hits	19
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

LDLR_MOUSE
θ value	2.36792 (rank : 219)	NC score	0.001618 (rank : 532)
Query Neighborhood Hits	443	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MUC7_HUMAN
θ value	2.36792 (rank : 220)	NC score	0.086370 (rank : 85)
Query Neighborhood Hits	443	Target Neighborhood Hits	538	Shared Neighborhood Hits	96
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PPAC3_MOUSE
θ value	2.36792 (rank : 221)	NC score	0.022237 (rank : 340)
Query Neighborhood Hits	443	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

PRG3_MOUSE
θ value	2.36792 (rank : 222)	NC score	0.022682 (rank : 334)
Query Neighborhood Hits	443	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

RAG2_HUMAN
θ value	2.36792 (rank : 223)	NC score	0.034333 (rank : 268)
Query Neighborhood Hits	443	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	P55895, Q8TBL4	Gene names	RAG2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

SC23B_HUMAN
θ value	2.36792 (rank : 224)	NC score	0.018603 (rank : 369)
Query Neighborhood Hits	443	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q15437, Q5W183, Q9BS15, Q9BSI2, Q9H1D7	Gene names	SEC23B
Domain Architecture
Description	Protein transport protein Sec23B (SEC23-related protein B).

SC23B_MOUSE
θ value	2.36792 (rank : 225)	NC score	0.018536 (rank : 370)
Query Neighborhood Hits	443	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D662, Q3U6B3, Q99K49, Q9QZ68	Gene names	Sec23b
Domain Architecture
Description	Protein transport protein Sec23B (SEC23-related protein B).

TAF9B_HUMAN
θ value	2.36792 (rank : 226)	NC score	0.026460 (rank : 313)
Query Neighborhood Hits	443	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBM6, Q9Y2S3	Gene names	TAF9B, TAF9L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L) (Neuronal cell death-related protein 7) (DN-7).

THUM1_HUMAN
θ value	2.36792 (rank : 227)	NC score	0.029957 (rank : 287)
Query Neighborhood Hits	443	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NXG2, Q9BWC3	Gene names	THUMPD1
Domain Architecture
Description	THUMP domain-containing protein 1.

TMPS9_HUMAN
θ value	2.36792 (rank : 228)	NC score	0.000956 (rank : 536)
Query Neighborhood Hits	443	Target Neighborhood Hits	276	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TULP4_HUMAN
θ value	2.36792 (rank : 229)	NC score	0.022494 (rank : 336)
Query Neighborhood Hits	443	Target Neighborhood Hits	426	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UBP5_HUMAN
θ value	2.36792 (rank : 230)	NC score	0.021149 (rank : 349)
Query Neighborhood Hits	443	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

ZN217_HUMAN
θ value	2.36792 (rank : 231)	NC score	0.005739 (rank : 498)
Query Neighborhood Hits	443	Target Neighborhood Hits	905	Shared Neighborhood Hits	46
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ADDB_MOUSE
θ value	3.0926 (rank : 232)	NC score	0.041091 (rank : 239)
Query Neighborhood Hits	443	Target Neighborhood Hits	574	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AKAP8_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.016878 (rank : 386)
Query Neighborhood Hits	443	Target Neighborhood Hits	166	Shared Neighborhood Hits	26
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

AQR_MOUSE
θ value	3.0926 (rank : 234)	NC score	0.010302 (rank : 451)
Query Neighborhood Hits	443	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

BAZ1A_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.027914 (rank : 305)
Query Neighborhood Hits	443	Target Neighborhood Hits	693	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ2A_MOUSE
θ value	3.0926 (rank : 236)	NC score	0.026283 (rank : 314)
Query Neighborhood Hits	443	Target Neighborhood Hits	744	Shared Neighborhood Hits	84
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CD68_MOUSE
θ value	3.0926 (rank : 237)	NC score	0.018265 (rank : 372)
Query Neighborhood Hits	443	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	P31996	Gene names	Cd68
Domain Architecture
Description	Macrosialin precursor (CD68 antigen).

CFDP1_MOUSE
θ value	3.0926 (rank : 238)	NC score	0.036089 (rank : 263)
Query Neighborhood Hits	443	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	O88271, O70565, Q9JMA5	Gene names	Cfdp1, Bcnt, Cfdp, Cp27
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur) (27 kDa craniofacial protein) (Protein Cp27).

DCR1A_HUMAN
θ value	3.0926 (rank : 239)	NC score	0.017176 (rank : 381)
Query Neighborhood Hits	443	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

DDX52_HUMAN
θ value	3.0926 (rank : 240)	NC score	0.001991 (rank : 530)
Query Neighborhood Hits	443	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DMD_HUMAN
θ value	3.0926 (rank : 241)	NC score	0.038670 (rank : 248)
Query Neighborhood Hits	443	Target Neighborhood Hits	1135	Shared Neighborhood Hits	74
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

EPC1_HUMAN
θ value	3.0926 (rank : 242)	NC score	0.009189 (rank : 463)
Query Neighborhood Hits	443	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

F126A_MOUSE
θ value	3.0926 (rank : 243)	NC score	0.024605 (rank : 324)
Query Neighborhood Hits	443	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P9N1, Q99NC4	Gene names	Fam126a, Drctnnb1a
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

FGD6_HUMAN
θ value	3.0926 (rank : 244)	NC score	0.010516 (rank : 450)
Query Neighborhood Hits	443	Target Neighborhood Hits	237	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

GIT1_MOUSE
θ value	3.0926 (rank : 245)	NC score	0.014012 (rank : 413)
Query Neighborhood Hits	443	Target Neighborhood Hits	341	Shared Neighborhood Hits	23
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GRIPE_HUMAN
θ value	3.0926 (rank : 246)	NC score	0.019091 (rank : 363)
Query Neighborhood Hits	443	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

LRBA_HUMAN
θ value	3.0926 (rank : 247)	NC score	0.016723 (rank : 387)
Query Neighborhood Hits	443	Target Neighborhood Hits	196	Shared Neighborhood Hits	24
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

MAGC1_HUMAN
θ value	3.0926 (rank : 248)	NC score	0.027988 (rank : 302)
Query Neighborhood Hits	443	Target Neighborhood Hits	431	Shared Neighborhood Hits	62
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MAGD2_HUMAN
θ value	3.0926 (rank : 249)	NC score	0.015041 (rank : 405)
Query Neighborhood Hits	443	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UNF1, O76058, Q5BJF3, Q8NAL6, Q9H218, Q9P0U9, Q9UM52	Gene names	MAGED2, BCG1
Domain Architecture
Description	Melanoma-associated antigen D2 (MAGE-D2 antigen) (MAGE-D) (Breast cancer-associated gene 1 protein) (BCG-1) (11B6) (Hepatocellular carcinoma-associated protein JCL-1).

MCPH1_MOUSE
θ value	3.0926 (rank : 250)	NC score	0.019723 (rank : 359)
Query Neighborhood Hits	443	Target Neighborhood Hits	116	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MK07_HUMAN
θ value	3.0926 (rank : 251)	NC score	-0.000275 (rank : 544)
Query Neighborhood Hits	443	Target Neighborhood Hits	1087	Shared Neighborhood Hits	58
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MTG8_HUMAN
θ value	3.0926 (rank : 252)	NC score	0.016968 (rank : 383)
Query Neighborhood Hits	443	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

PA24F_HUMAN
θ value	3.0926 (rank : 253)	NC score	0.026485 (rank : 311)
Query Neighborhood Hits	443	Target Neighborhood Hits	78	Shared Neighborhood Hits	10
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PO6F2_HUMAN
θ value	3.0926 (rank : 254)	NC score	0.012293 (rank : 435)
Query Neighborhood Hits	443	Target Neighborhood Hits	618	Shared Neighborhood Hits	50
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

RBFAL_MOUSE
θ value	3.0926 (rank : 255)	NC score	0.025204 (rank : 321)
Query Neighborhood Hits	443	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3B9	Gene names
Domain Architecture	No domain graphic available
Description	Putative ribosome-binding factor A, mitochondrial precursor.

RPGF6_HUMAN
θ value	3.0926 (rank : 256)	NC score	0.011100 (rank : 443)
Query Neighborhood Hits	443	Target Neighborhood Hits	266	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

RSF1_HUMAN
θ value	3.0926 (rank : 257)	NC score	0.050714 (rank : 207)
Query Neighborhood Hits	443	Target Neighborhood Hits	539	Shared Neighborhood Hits	90
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RTN1_HUMAN
θ value	3.0926 (rank : 258)	NC score	0.037691 (rank : 252)
Query Neighborhood Hits	443	Target Neighborhood Hits	173	Shared Neighborhood Hits	33
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SEMG1_HUMAN
θ value	3.0926 (rank : 259)	NC score	0.030181 (rank : 286)
Query Neighborhood Hits	443	Target Neighborhood Hits	200	Shared Neighborhood Hits	27
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SEPT9_HUMAN
θ value	3.0926 (rank : 260)	NC score	0.017980 (rank : 374)
Query Neighborhood Hits	443	Target Neighborhood Hits	706	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SPTA2_HUMAN
θ value	3.0926 (rank : 261)	NC score	0.013716 (rank : 418)
Query Neighborhood Hits	443	Target Neighborhood Hits	888	Shared Neighborhood Hits	44
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRPK1_MOUSE
θ value	3.0926 (rank : 262)	NC score	0.004246 (rank : 505)
Query Neighborhood Hits	443	Target Neighborhood Hits	639	Shared Neighborhood Hits	30
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

SV2C_HUMAN
θ value	3.0926 (rank : 263)	NC score	0.010774 (rank : 447)
Query Neighborhood Hits	443	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

SVIL_MOUSE
θ value	3.0926 (rank : 264)	NC score	0.022664 (rank : 335)
Query Neighborhood Hits	443	Target Neighborhood Hits	439	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TACT_HUMAN
θ value	3.0926 (rank : 265)	NC score	0.026936 (rank : 310)
Query Neighborhood Hits	443	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

TBX10_HUMAN
θ value	3.0926 (rank : 266)	NC score	0.003538 (rank : 509)
Query Neighborhood Hits	443	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TOM1_HUMAN
θ value	3.0926 (rank : 267)	NC score	0.009004 (rank : 465)
Query Neighborhood Hits	443	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

UBP10_HUMAN
θ value	3.0926 (rank : 268)	NC score	0.011797 (rank : 437)
Query Neighborhood Hits	443	Target Neighborhood Hits	153	Shared Neighborhood Hits	20
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

ZF276_HUMAN
θ value	3.0926 (rank : 269)	NC score	-0.000352 (rank : 545)
Query Neighborhood Hits	443	Target Neighborhood Hits	768	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N554	Gene names	ZFP276
Domain Architecture	No domain graphic available
Description	Zinc finger protein 276 homolog (Zfp-276).

ZHX2_HUMAN
θ value	3.0926 (rank : 270)	NC score	0.009797 (rank : 458)
Query Neighborhood Hits	443	Target Neighborhood Hits	347	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6X8	Gene names	ZHX2, AFR1, KIAA0854, RAF
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

ZHX2_MOUSE
θ value	3.0926 (rank : 271)	NC score	0.013743 (rank : 417)
Query Neighborhood Hits	443	Target Neighborhood Hits	435	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

BCOR_HUMAN
θ value	4.03905 (rank : 272)	NC score	0.014360 (rank : 410)
Query Neighborhood Hits	443	Target Neighborhood Hits	609	Shared Neighborhood Hits	55
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BMP3_MOUSE
θ value	4.03905 (rank : 273)	NC score	0.006428 (rank : 491)
Query Neighborhood Hits	443	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE5	Gene names	Bmp3
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 3 precursor (BMP-3).

BNC2_HUMAN
θ value	4.03905 (rank : 274)	NC score	0.017532 (rank : 377)
Query Neighborhood Hits	443	Target Neighborhood Hits	439	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

CCD47_HUMAN
θ value	4.03905 (rank : 275)	NC score	0.037122 (rank : 255)
Query Neighborhood Hits	443	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

CCD82_MOUSE
θ value	4.03905 (rank : 276)	NC score	0.034219 (rank : 269)
Query Neighborhood Hits	443	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PG04, Q3V462	Gene names	Ccdc82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

CU025_HUMAN
θ value	4.03905 (rank : 277)	NC score	0.012817 (rank : 428)
Query Neighborhood Hits	443	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y426, Q5R2V7, Q6AHX8, Q9NSE6	Gene names	C21orf25, C21orf258
Domain Architecture	No domain graphic available
Description	Protein C21orf25 precursor.

EMSY_HUMAN
θ value	4.03905 (rank : 278)	NC score	0.028717 (rank : 298)
Query Neighborhood Hits	443	Target Neighborhood Hits	296	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

HXA5_MOUSE
θ value	4.03905 (rank : 279)	NC score	-0.000882 (rank : 546)
Query Neighborhood Hits	443	Target Neighborhood Hits	338	Shared Neighborhood Hits	8
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

LATS1_HUMAN
θ value	4.03905 (rank : 280)	NC score	0.003328 (rank : 513)
Query Neighborhood Hits	443	Target Neighborhood Hits	1057	Shared Neighborhood Hits	56
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

LPXN_HUMAN
θ value	4.03905 (rank : 281)	NC score	0.001660 (rank : 531)
Query Neighborhood Hits	443	Target Neighborhood Hits	159	Shared Neighborhood Hits	5
SwissProt Accessions	O60711	Gene names	LPXN, LDLP
Domain Architecture
Description	Leupaxin.

MEFV_MOUSE
θ value	4.03905 (rank : 282)	NC score	0.007335 (rank : 484)
Query Neighborhood Hits	443	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MGRN1_HUMAN
θ value	4.03905 (rank : 283)	NC score	0.015337 (rank : 403)
Query Neighborhood Hits	443	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MTG8_MOUSE
θ value	4.03905 (rank : 284)	NC score	0.015454 (rank : 402)
Query Neighborhood Hits	443	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

PDE4D_MOUSE
θ value	4.03905 (rank : 285)	NC score	0.009031 (rank : 464)
Query Neighborhood Hits	443	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

REST_MOUSE
θ value	4.03905 (rank : 286)	NC score	0.013853 (rank : 415)
Query Neighborhood Hits	443	Target Neighborhood Hits	1506	Shared Neighborhood Hits	85
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SETBP_HUMAN
θ value	4.03905 (rank : 287)	NC score	0.034706 (rank : 266)
Query Neighborhood Hits	443	Target Neighborhood Hits	305	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETX_HUMAN
θ value	4.03905 (rank : 288)	NC score	0.015540 (rank : 400)
Query Neighborhood Hits	443	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

TIF1G_MOUSE
θ value	4.03905 (rank : 289)	NC score	0.012823 (rank : 427)
Query Neighborhood Hits	443	Target Neighborhood Hits	498	Shared Neighborhood Hits	47
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TMUB2_MOUSE
θ value	4.03905 (rank : 290)	NC score	0.011651 (rank : 438)
Query Neighborhood Hits	443	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q3V209, Q8K0X0, Q91YQ0, Q9D8C5	Gene names	Tmub2
Domain Architecture	No domain graphic available
Description	Transmembrane and ubiquitin-like domain-containing protein 2.

UBP33_HUMAN
θ value	4.03905 (rank : 291)	NC score	0.009844 (rank : 457)
Query Neighborhood Hits	443	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

VLDLR_HUMAN
θ value	4.03905 (rank : 292)	NC score	0.002975 (rank : 519)
Query Neighborhood Hits	443	Target Neighborhood Hits	383	Shared Neighborhood Hits	7
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

XKR5_HUMAN
θ value	4.03905 (rank : 293)	NC score	0.013683 (rank : 419)
Query Neighborhood Hits	443	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UX68, Q5GH74	Gene names	XKR5, XRG5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

XRCC1_MOUSE
θ value	4.03905 (rank : 294)	NC score	0.039218 (rank : 246)
Query Neighborhood Hits	443	Target Neighborhood Hits	242	Shared Neighborhood Hits	45
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZCH11_HUMAN
θ value	4.03905 (rank : 295)	NC score	0.021612 (rank : 345)
Query Neighborhood Hits	443	Target Neighborhood Hits	278	Shared Neighborhood Hits	40
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ANC1_HUMAN
θ value	5.27518 (rank : 296)	NC score	0.008230 (rank : 475)
Query Neighborhood Hits	443	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ANGL2_MOUSE
θ value	5.27518 (rank : 297)	NC score	0.002010 (rank : 529)
Query Neighborhood Hits	443	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANK3_HUMAN
θ value	5.27518 (rank : 298)	NC score	0.016957 (rank : 385)
Query Neighborhood Hits	443	Target Neighborhood Hits	853	Shared Neighborhood Hits	93
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

AP180_MOUSE
θ value	5.27518 (rank : 299)	NC score	0.027583 (rank : 308)
Query Neighborhood Hits	443	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

ATF4_MOUSE
θ value	5.27518 (rank : 300)	NC score	0.017865 (rank : 376)
Query Neighborhood Hits	443	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

CEL_HUMAN
θ value	5.27518 (rank : 301)	NC score	0.013338 (rank : 421)
Query Neighborhood Hits	443	Target Neighborhood Hits	896	Shared Neighborhood Hits	68
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CGRE1_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.017951 (rank : 375)
Query Neighborhood Hits	443	Target Neighborhood Hits	354	Shared Neighborhood Hits	30
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CNGB3_HUMAN
θ value	5.27518 (rank : 303)	NC score	0.010243 (rank : 454)
Query Neighborhood Hits	443	Target Neighborhood Hits	206	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNOT3_MOUSE
θ value	5.27518 (rank : 304)	NC score	0.038812 (rank : 247)
Query Neighborhood Hits	443	Target Neighborhood Hits	504	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

EF2K_HUMAN
θ value	5.27518 (rank : 305)	NC score	0.019086 (rank : 364)
Query Neighborhood Hits	443	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_MOUSE
θ value	5.27518 (rank : 306)	NC score	0.021232 (rank : 348)
Query Neighborhood Hits	443	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

ESCO1_HUMAN
θ value	5.27518 (rank : 307)	NC score	0.029138 (rank : 294)
Query Neighborhood Hits	443	Target Neighborhood Hits	361	Shared Neighborhood Hits	55
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

FIGN_HUMAN
θ value	5.27518 (rank : 308)	NC score	0.005975 (rank : 495)
Query Neighborhood Hits	443	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

FOXR2_HUMAN
θ value	5.27518 (rank : 309)	NC score	0.006389 (rank : 492)
Query Neighborhood Hits	443	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PJQ5	Gene names	FOXR2, FOXN6
Domain Architecture	No domain graphic available
Description	Forkhead box protein R2 (Forkhead box protein N6).

GAK7_HUMAN
θ value	5.27518 (rank : 310)	NC score	0.007794 (rank : 481)
Query Neighborhood Hits	443	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

HLX1_HUMAN
θ value	5.27518 (rank : 311)	NC score	0.006630 (rank : 489)
Query Neighborhood Hits	443	Target Neighborhood Hits	370	Shared Neighborhood Hits	16
SwissProt Accessions	Q14774, Q15988	Gene names	HLX1
Domain Architecture
Description	Homeobox protein HLX1 (Homeobox protein HB24).

HUNK_HUMAN
θ value	5.27518 (rank : 312)	NC score	-0.002698 (rank : 552)
Query Neighborhood Hits	443	Target Neighborhood Hits	884	Shared Neighborhood Hits	23
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

LAD1_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.033979 (rank : 272)
Query Neighborhood Hits	443	Target Neighborhood Hits	441	Shared Neighborhood Hits	60
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LARP1_HUMAN
θ value	5.27518 (rank : 314)	NC score	0.029602 (rank : 291)
Query Neighborhood Hits	443	Target Neighborhood Hits	242	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

LY10_HUMAN
θ value	5.27518 (rank : 315)	NC score	0.010891 (rank : 446)
Query Neighborhood Hits	443	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MAGB6_HUMAN
θ value	5.27518 (rank : 316)	NC score	0.014464 (rank : 409)
Query Neighborhood Hits	443	Target Neighborhood Hits	184	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

MARK2_MOUSE
θ value	5.27518 (rank : 317)	NC score	-0.001265 (rank : 549)
Query Neighborhood Hits	443	Target Neighborhood Hits	1018	Shared Neighborhood Hits	52
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

MARK4_MOUSE
θ value	5.27518 (rank : 318)	NC score	-0.002843 (rank : 553)
Query Neighborhood Hits	443	Target Neighborhood Hits	898	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MDC1_MOUSE
θ value	5.27518 (rank : 319)	NC score	0.052626 (rank : 196)
Query Neighborhood Hits	443	Target Neighborhood Hits	998	Shared Neighborhood Hits	130
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUCDL_HUMAN
θ value	5.27518 (rank : 320)	NC score	0.029735 (rank : 289)
Query Neighborhood Hits	443	Target Neighborhood Hits	777	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOA6_MOUSE
θ value	5.27518 (rank : 321)	NC score	0.029457 (rank : 293)
Query Neighborhood Hits	443	Target Neighborhood Hits	1076	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFASC_HUMAN
θ value	5.27518 (rank : 322)	NC score	0.003036 (rank : 516)
Query Neighborhood Hits	443	Target Neighborhood Hits	497	Shared Neighborhood Hits	25
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NFASC_MOUSE
θ value	5.27518 (rank : 323)	NC score	0.003000 (rank : 518)
Query Neighborhood Hits	443	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

NSD1_MOUSE
θ value	5.27518 (rank : 324)	NC score	0.029618 (rank : 290)
Query Neighborhood Hits	443	Target Neighborhood Hits	472	Shared Neighborhood Hits	59
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

OXRP_HUMAN
θ value	5.27518 (rank : 325)	NC score	0.016359 (rank : 389)
Query Neighborhood Hits	443	Target Neighborhood Hits	544	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PDE4D_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.008949 (rank : 467)
Query Neighborhood Hits	443	Target Neighborhood Hits	122	Shared Neighborhood Hits	24
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

PGCA_MOUSE
θ value	5.27518 (rank : 327)	NC score	0.021837 (rank : 343)
Query Neighborhood Hits	443	Target Neighborhood Hits	643	Shared Neighborhood Hits	63
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PTN4_HUMAN
θ value	5.27518 (rank : 328)	NC score	0.005604 (rank : 500)
Query Neighborhood Hits	443	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RAI1_HUMAN
θ value	5.27518 (rank : 329)	NC score	0.027664 (rank : 307)
Query Neighborhood Hits	443	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RTP3_MOUSE
θ value	5.27518 (rank : 330)	NC score	0.029111 (rank : 295)
Query Neighborhood Hits	443	Target Neighborhood Hits	374	Shared Neighborhood Hits	48
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SAPS1_HUMAN
θ value	5.27518 (rank : 331)	NC score	0.020887 (rank : 352)
Query Neighborhood Hits	443	Target Neighborhood Hits	704	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SETBP_MOUSE
θ value	5.27518 (rank : 332)	NC score	0.036663 (rank : 256)
Query Neighborhood Hits	443	Target Neighborhood Hits	352	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SFR12_HUMAN
θ value	5.27518 (rank : 333)	NC score	0.044526 (rank : 228)
Query Neighborhood Hits	443	Target Neighborhood Hits	553	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SMCE1_MOUSE
θ value	5.27518 (rank : 334)	NC score	0.025550 (rank : 316)
Query Neighborhood Hits	443	Target Neighborhood Hits	409	Shared Neighborhood Hits	43
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SP7_HUMAN
θ value	5.27518 (rank : 335)	NC score	-0.001490 (rank : 550)
Query Neighborhood Hits	443	Target Neighborhood Hits	734	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

SYNJ1_MOUSE
θ value	5.27518 (rank : 336)	NC score	0.030930 (rank : 282)
Query Neighborhood Hits	443	Target Neighborhood Hits	516	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TCF20_HUMAN
θ value	5.27518 (rank : 337)	NC score	0.023615 (rank : 329)
Query Neighborhood Hits	443	Target Neighborhood Hits	323	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCOF_HUMAN
θ value	5.27518 (rank : 338)	NC score	0.072240 (rank : 111)
Query Neighborhood Hits	443	Target Neighborhood Hits	543	Shared Neighborhood Hits	108
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ABCA7_HUMAN
θ value	6.88961 (rank : 339)	NC score	0.000690 (rank : 538)
Query Neighborhood Hits	443	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

AKAP2_MOUSE
θ value	6.88961 (rank : 340)	NC score	0.048300 (rank : 217)
Query Neighborhood Hits	443	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ANK2_HUMAN
θ value	6.88961 (rank : 341)	NC score	0.028426 (rank : 300)
Query Neighborhood Hits	443	Target Neighborhood Hits	1615	Shared Neighborhood Hits	170
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

APC_HUMAN
θ value	6.88961 (rank : 342)	NC score	0.028764 (rank : 297)
Query Neighborhood Hits	443	Target Neighborhood Hits	603	Shared Neighborhood Hits	85
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BRE1A_HUMAN
θ value	6.88961 (rank : 343)	NC score	0.016214 (rank : 391)
Query Neighborhood Hits	443	Target Neighborhood Hits	1071	Shared Neighborhood Hits	77
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BUB1_HUMAN
θ value	6.88961 (rank : 344)	NC score	0.007137 (rank : 486)
Query Neighborhood Hits	443	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

CARD6_HUMAN
θ value	6.88961 (rank : 345)	NC score	0.023146 (rank : 332)
Query Neighborhood Hits	443	Target Neighborhood Hits	145	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

CCD82_HUMAN
θ value	6.88961 (rank : 346)	NC score	0.036565 (rank : 259)
Query Neighborhood Hits	443	Target Neighborhood Hits	137	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

CCDC7_HUMAN
θ value	6.88961 (rank : 347)	NC score	0.013877 (rank : 414)
Query Neighborhood Hits	443	Target Neighborhood Hits	253	Shared Neighborhood Hits	21
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

CMTA1_HUMAN
θ value	6.88961 (rank : 348)	NC score	0.010989 (rank : 444)
Query Neighborhood Hits	443	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

DDX51_HUMAN
θ value	6.88961 (rank : 349)	NC score	0.005695 (rank : 499)
Query Neighborhood Hits	443	Target Neighborhood Hits	332	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DIAP3_MOUSE
θ value	6.88961 (rank : 350)	NC score	0.008178 (rank : 477)
Query Neighborhood Hits	443	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DMP1_MOUSE
θ value	6.88961 (rank : 351)	NC score	0.083721 (rank : 91)
Query Neighborhood Hits	443	Target Neighborhood Hits	498	Shared Neighborhood Hits	116
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DPPA4_HUMAN
θ value	6.88961 (rank : 352)	NC score	0.008379 (rank : 472)
Query Neighborhood Hits	443	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q7L190, Q9H9N5, Q9NVI6	Gene names	DPPA4
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 4.

ERR1_HUMAN
θ value	6.88961 (rank : 353)	NC score	0.002707 (rank : 521)
Query Neighborhood Hits	443	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

F10A4_HUMAN
θ value	6.88961 (rank : 354)	NC score	0.023263 (rank : 331)
Query Neighborhood Hits	443	Target Neighborhood Hits	249	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

F126A_HUMAN
θ value	6.88961 (rank : 355)	NC score	0.018883 (rank : 366)
Query Neighborhood Hits	443	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYI3, Q6N010, Q75MR4, Q7LDZ4, Q96MX1, Q96NQ6	Gene names	FAM126A, DRCTNNB1A
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

FOXC1_MOUSE
θ value	6.88961 (rank : 356)	NC score	0.007293 (rank : 485)
Query Neighborhood Hits	443	Target Neighborhood Hits	218	Shared Neighborhood Hits	28
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

GOGA4_MOUSE
θ value	6.88961 (rank : 357)	NC score	0.013140 (rank : 423)
Query Neighborhood Hits	443	Target Neighborhood Hits	1939	Shared Neighborhood Hits	106
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GP179_HUMAN
θ value	6.88961 (rank : 358)	NC score	0.020666 (rank : 354)
Query Neighborhood Hits	443	Target Neighborhood Hits	372	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

HDGR3_HUMAN
θ value	6.88961 (rank : 359)	NC score	0.011594 (rank : 441)
Query Neighborhood Hits	443	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

IF4G1_HUMAN
θ value	6.88961 (rank : 360)	NC score	0.027218 (rank : 309)
Query Neighborhood Hits	443	Target Neighborhood Hits	347	Shared Neighborhood Hits	58
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

ITF2_HUMAN
θ value	6.88961 (rank : 361)	NC score	0.013333 (rank : 422)
Query Neighborhood Hits	443	Target Neighborhood Hits	168	Shared Neighborhood Hits	17
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
θ value	6.88961 (rank : 362)	NC score	0.016404 (rank : 388)
Query Neighborhood Hits	443	Target Neighborhood Hits	154	Shared Neighborhood Hits	20
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

JIP4_MOUSE
θ value	6.88961 (rank : 363)	NC score	0.014023 (rank : 412)
Query Neighborhood Hits	443	Target Neighborhood Hits	593	Shared Neighborhood Hits	48
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

LPIN1_MOUSE
θ value	6.88961 (rank : 364)	NC score	0.009452 (rank : 461)
Query Neighborhood Hits	443	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZP3, Q9CQI2, Q9JLG6	Gene names	Lpin1, Fld
Domain Architecture
Description	Lipin-1 (Fatty liver dystrophy protein).

LTK_HUMAN
θ value	6.88961 (rank : 365)	NC score	-0.004555 (rank : 554)
Query Neighborhood Hits	443	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

MILK1_MOUSE
θ value	6.88961 (rank : 366)	NC score	0.029523 (rank : 292)
Query Neighborhood Hits	443	Target Neighborhood Hits	788	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NU205_HUMAN
θ value	6.88961 (rank : 367)	NC score	0.015106 (rank : 404)
Query Neighborhood Hits	443	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

PRG3_HUMAN
θ value	6.88961 (rank : 368)	NC score	0.015747 (rank : 399)
Query Neighborhood Hits	443	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

PTPRG_HUMAN
θ value	6.88961 (rank : 369)	NC score	0.007030 (rank : 487)
Query Neighborhood Hits	443	Target Neighborhood Hits	231	Shared Neighborhood Hits	44
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

SEC62_HUMAN
θ value	6.88961 (rank : 370)	NC score	0.034626 (rank : 267)
Query Neighborhood Hits	443	Target Neighborhood Hits	100	Shared Neighborhood Hits	26
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

SHAN1_HUMAN
θ value	6.88961 (rank : 371)	NC score	0.016121 (rank : 395)
Query Neighborhood Hits	443	Target Neighborhood Hits	1041	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SIP1_HUMAN
θ value	6.88961 (rank : 372)	NC score	0.002888 (rank : 520)
Query Neighborhood Hits	443	Target Neighborhood Hits	832	Shared Neighborhood Hits	51
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SIP1_MOUSE
θ value	6.88961 (rank : 373)	NC score	0.002312 (rank : 524)
Query Neighborhood Hits	443	Target Neighborhood Hits	870	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

SNX19_HUMAN
θ value	6.88961 (rank : 374)	NC score	0.009853 (rank : 456)
Query Neighborhood Hits	443	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

STAM2_MOUSE
θ value	6.88961 (rank : 375)	NC score	0.007628 (rank : 483)
Query Neighborhood Hits	443	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STK10_HUMAN
θ value	6.88961 (rank : 376)	NC score	0.001358 (rank : 533)
Query Neighborhood Hits	443	Target Neighborhood Hits	1921	Shared Neighborhood Hits	102
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SYTL5_MOUSE
θ value	6.88961 (rank : 377)	NC score	0.031962 (rank : 276)
Query Neighborhood Hits	443	Target Neighborhood Hits	154	Shared Neighborhood Hits	14
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

TE2IP_HUMAN
θ value	6.88961 (rank : 378)	NC score	0.012715 (rank : 429)
Query Neighborhood Hits	443	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

THA11_HUMAN
θ value	6.88961 (rank : 379)	NC score	0.012847 (rank : 426)
Query Neighborhood Hits	443	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK4, O94795	Gene names	THAP11
Domain Architecture
Description	THAP domain-containing protein 11.

TMM29_HUMAN
θ value	6.88961 (rank : 380)	NC score	0.024637 (rank : 323)
Query Neighborhood Hits	443	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDB6, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q9UI49	Gene names	TMEM29
Domain Architecture	No domain graphic available
Description	Transmembrane protein 29.

TOIP2_MOUSE
θ value	6.88961 (rank : 381)	NC score	0.017360 (rank : 379)
Query Neighborhood Hits	443	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

TTC1_MOUSE
θ value	6.88961 (rank : 382)	NC score	0.015008 (rank : 406)
Query Neighborhood Hits	443	Target Neighborhood Hits	145	Shared Neighborhood Hits	13
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

ZBT10_HUMAN
θ value	6.88961 (rank : 383)	NC score	-0.000081 (rank : 543)
Query Neighborhood Hits	443	Target Neighborhood Hits	831	Shared Neighborhood Hits	21
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

AHI1_HUMAN
θ value	8.99809 (rank : 384)	NC score	0.003497 (rank : 510)
Query Neighborhood Hits	443	Target Neighborhood Hits	537	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AMOL1_MOUSE
θ value	8.99809 (rank : 385)	NC score	0.012342 (rank : 434)
Query Neighborhood Hits	443	Target Neighborhood Hits	445	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

ATRX_HUMAN
θ value	8.99809 (rank : 386)	NC score	0.029891 (rank : 288)
Query Neighborhood Hits	443	Target Neighborhood Hits	842	Shared Neighborhood Hits	104
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BIN1_HUMAN
θ value	8.99809 (rank : 387)	NC score	0.028560 (rank : 299)
Query Neighborhood Hits	443	Target Neighborhood Hits	335	Shared Neighborhood Hits	48
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BNC2_MOUSE
θ value	8.99809 (rank : 388)	NC score	0.013804 (rank : 416)
Query Neighborhood Hits	443	Target Neighborhood Hits	456	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

CCHCR_HUMAN
θ value	8.99809 (rank : 389)	NC score	0.011650 (rank : 439)
Query Neighborhood Hits	443	Target Neighborhood Hits	717	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CDC27_HUMAN
θ value	8.99809 (rank : 390)	NC score	0.010960 (rank : 445)
Query Neighborhood Hits	443	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CENG1_HUMAN
θ value	8.99809 (rank : 391)	NC score	0.006491 (rank : 490)
Query Neighborhood Hits	443	Target Neighborhood Hits	544	Shared Neighborhood Hits	33
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	8.99809 (rank : 392)	NC score	0.007845 (rank : 480)
Query Neighborhood Hits	443	Target Neighborhood Hits	531	Shared Neighborhood Hits	36
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CJ012_HUMAN
θ value	8.99809 (rank : 393)	NC score	0.044169 (rank : 229)
Query Neighborhood Hits	443	Target Neighborhood Hits	467	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CR025_HUMAN
θ value	8.99809 (rank : 394)	NC score	0.025362 (rank : 320)
Query Neighborhood Hits	443	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	Q96B23, Q5XG78, Q6N058, Q86TB5, Q8TCQ5	Gene names	C18orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25.

CR025_MOUSE
θ value	8.99809 (rank : 395)	NC score	0.022243 (rank : 339)
Query Neighborhood Hits	443	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BH50, Q3TQ72, Q8BU43	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25 homolog.

CT032_HUMAN
θ value	8.99809 (rank : 396)	NC score	0.009214 (rank : 462)
Query Neighborhood Hits	443	Target Neighborhood Hits	235	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DDFL1_HUMAN
θ value	8.99809 (rank : 397)	NC score	0.010542 (rank : 449)
Query Neighborhood Hits	443	Target Neighborhood Hits	353	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DNL4_HUMAN
θ value	8.99809 (rank : 398)	NC score	0.008065 (rank : 478)
Query Neighborhood Hits	443	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

FOXO4_MOUSE
θ value	8.99809 (rank : 399)	NC score	0.003428 (rank : 511)
Query Neighborhood Hits	443	Target Neighborhood Hits	168	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WVH3	Gene names	Mllt7, Afx, Afx1, Fkhr3, Foxo4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Afxh) (Forkhead box protein O4).

GOG8A_HUMAN
θ value	8.99809 (rank : 400)	NC score	0.010253 (rank : 453)
Query Neighborhood Hits	443	Target Neighborhood Hits	635	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

HAT1_HUMAN
θ value	8.99809 (rank : 401)	NC score	0.011630 (rank : 440)
Query Neighborhood Hits	443	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	O14929, Q49A44, Q53QF0, Q53SU4	Gene names	HAT1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48).

HOME2_MOUSE
θ value	8.99809 (rank : 402)	NC score	0.012475 (rank : 431)
Query Neighborhood Hits	443	Target Neighborhood Hits	882	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

IF4G1_MOUSE
θ value	8.99809 (rank : 403)	NC score	0.022742 (rank : 333)
Query Neighborhood Hits	443	Target Neighborhood Hits	534	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

INVS_MOUSE
θ value	8.99809 (rank : 404)	NC score	0.010277 (rank : 452)
Query Neighborhood Hits	443	Target Neighborhood Hits	609	Shared Neighborhood Hits	52
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

K0195_HUMAN
θ value	8.99809 (rank : 405)	NC score	0.005943 (rank : 496)
Query Neighborhood Hits	443	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

K0256_MOUSE
θ value	8.99809 (rank : 406)	NC score	0.008247 (rank : 473)
Query Neighborhood Hits	443	Target Neighborhood Hits	121	Shared Neighborhood Hits	23
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

K0323_MOUSE
θ value	8.99809 (rank : 407)	NC score	0.011410 (rank : 442)
Query Neighborhood Hits	443	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U38, Q8BGJ6, Q8C082	Gene names	Kiaa0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

LATS1_MOUSE
θ value	8.99809 (rank : 408)	NC score	0.003000 (rank : 517)
Query Neighborhood Hits	443	Target Neighborhood Hits	1027	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

LRC33_MOUSE
θ value	8.99809 (rank : 409)	NC score	-0.000046 (rank : 542)
Query Neighborhood Hits	443	Target Neighborhood Hits	296	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

LYST_MOUSE
θ value	8.99809 (rank : 410)	NC score	0.005021 (rank : 502)
Query Neighborhood Hits	443	Target Neighborhood Hits	286	Shared Neighborhood Hits	13
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

MACF1_HUMAN
θ value	8.99809 (rank : 411)	NC score	0.016109 (rank : 396)
Query Neighborhood Hits	443	Target Neighborhood Hits	1341	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	8.99809 (rank : 412)	NC score	0.018186 (rank : 373)
Query Neighborhood Hits	443	Target Neighborhood Hits	1321	Shared Neighborhood Hits	84
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MAML1_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.015955 (rank : 398)
Query Neighborhood Hits	443	Target Neighborhood Hits	228	Shared Neighborhood Hits	36
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MGR8_HUMAN
θ value	8.99809 (rank : 414)	NC score	0.002059 (rank : 527)
Query Neighborhood Hits	443	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MLL2_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.041181 (rank : 238)
Query Neighborhood Hits	443	Target Neighborhood Hits	1788	Shared Neighborhood Hits	143
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MRE11_MOUSE
θ value	8.99809 (rank : 416)	NC score	0.007926 (rank : 479)
Query Neighborhood Hits	443	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

NCKX1_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.049037 (rank : 215)
Query Neighborhood Hits	443	Target Neighborhood Hits	223	Shared Neighborhood Hits	70
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

NCOA5_HUMAN
θ value	8.99809 (rank : 418)	NC score	0.012649 (rank : 430)
Query Neighborhood Hits	443	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

PDZD2_HUMAN
θ value	8.99809 (rank : 419)	NC score	0.017502 (rank : 378)
Query Neighborhood Hits	443	Target Neighborhood Hits	772	Shared Neighborhood Hits	78
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PEG3_HUMAN
θ value	8.99809 (rank : 420)	NC score	0.000990 (rank : 535)
Query Neighborhood Hits	443	Target Neighborhood Hits	800	Shared Neighborhood Hits	39
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

PLVAP_HUMAN
θ value	8.99809 (rank : 421)	NC score	0.013384 (rank : 420)
Query Neighborhood Hits	443	Target Neighborhood Hits	397	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

PO6F1_MOUSE
θ value	8.99809 (rank : 422)	NC score	0.005989 (rank : 494)
Query Neighborhood Hits	443	Target Neighborhood Hits	581	Shared Neighborhood Hits	35
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PREX1_HUMAN
θ value	8.99809 (rank : 423)	NC score	0.006657 (rank : 488)
Query Neighborhood Hits	443	Target Neighborhood Hits	177	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PTPRN_MOUSE
θ value	8.99809 (rank : 424)	NC score	0.004657 (rank : 504)
Query Neighborhood Hits	443	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RB6I2_HUMAN
θ value	8.99809 (rank : 425)	NC score	0.011888 (rank : 436)
Query Neighborhood Hits	443	Target Neighborhood Hits	1584	Shared Neighborhood Hits	92
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RBBP6_HUMAN
θ value	8.99809 (rank : 426)	NC score	0.042068 (rank : 233)
Query Neighborhood Hits	443	Target Neighborhood Hits	1135	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RHBD3_HUMAN
θ value	8.99809 (rank : 427)	NC score	0.019644 (rank : 360)
Query Neighborhood Hits	443	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3P4, Q6I9X3, Q9UGQ7	Gene names	RHBDD3, C22orf3
Domain Architecture
Description	Rhomboid domain-containing protein 3.

RIF1_MOUSE
θ value	8.99809 (rank : 428)	NC score	0.023341 (rank : 330)
Query Neighborhood Hits	443	Target Neighborhood Hits	315	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

S4A7_MOUSE
θ value	8.99809 (rank : 429)	NC score	0.004169 (rank : 506)
Query Neighborhood Hits	443	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

SAFB2_HUMAN
θ value	8.99809 (rank : 430)	NC score	0.016276 (rank : 390)
Query Neighborhood Hits	443	Target Neighborhood Hits	720	Shared Neighborhood Hits	67
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SCN7A_HUMAN
θ value	8.99809 (rank : 431)	NC score	0.002016 (rank : 528)
Query Neighborhood Hits	443	Target Neighborhood Hits	135	Shared Neighborhood Hits	12
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SEM6C_HUMAN
θ value	8.99809 (rank : 432)	NC score	0.003357 (rank : 512)
Query Neighborhood Hits	443	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SMRC1_MOUSE
θ value	8.99809 (rank : 433)	NC score	0.031166 (rank : 280)
Query Neighborhood Hits	443	Target Neighborhood Hits	459	Shared Neighborhood Hits	79
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SPDYB_MOUSE
θ value	8.99809 (rank : 434)	NC score	0.008219 (rank : 476)
Query Neighborhood Hits	443	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q5IBH6	Gene names	Spdyb
Domain Architecture	No domain graphic available
Description	Speedy protein B (Rapid inducer of G2/M progression in oocytes B) (RINGO B) (mSpy/Ringo B).

SRCA_HUMAN
θ value	8.99809 (rank : 435)	NC score	0.048438 (rank : 216)
Query Neighborhood Hits	443	Target Neighborhood Hits	380	Shared Neighborhood Hits	90
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

STRN3_HUMAN
θ value	8.99809 (rank : 436)	NC score	0.003986 (rank : 507)
Query Neighborhood Hits	443	Target Neighborhood Hits	316	Shared Neighborhood Hits	13
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

TEX14_HUMAN
θ value	8.99809 (rank : 437)	NC score	0.008243 (rank : 474)
Query Neighborhood Hits	443	Target Neighborhood Hits	1103	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

THUM1_MOUSE
θ value	8.99809 (rank : 438)	NC score	0.018366 (rank : 371)
Query Neighborhood Hits	443	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	Q99J36, Q3U6Y3	Gene names	Thumpd1
Domain Architecture
Description	THUMP domain-containing protein 1.

ULE1B_MOUSE
θ value	8.99809 (rank : 439)	NC score	0.008599 (rank : 470)
Query Neighborhood Hits	443	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ULK1_MOUSE
θ value	8.99809 (rank : 440)	NC score	-0.002363 (rank : 551)
Query Neighborhood Hits	443	Target Neighborhood Hits	1214	Shared Neighborhood Hits	50
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ZN516_MOUSE
θ value	8.99809 (rank : 441)	NC score	0.002116 (rank : 526)
Query Neighborhood Hits	443	Target Neighborhood Hits	1197	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN644_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.000684 (rank : 539)
Query Neighborhood Hits	443	Target Neighborhood Hits	704	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H582, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9	Gene names	ZNF644, KIAA1221, ZEP2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2).

ZN711_HUMAN
θ value	8.99809 (rank : 443)	NC score	-0.000967 (rank : 547)
Query Neighborhood Hits	443	Target Neighborhood Hits	751	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

ACINU_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.051841 (rank : 201)
Query Neighborhood Hits	443	Target Neighborhood Hits	712	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ALS2_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.056883 (rank : 170)
Query Neighborhood Hits	443	Target Neighborhood Hits	121	Shared Neighborhood Hits	10
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.055435 (rank : 177)
Query Neighborhood Hits	443	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

APBB2_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.093857 (rank : 69)
Query Neighborhood Hits	443	Target Neighborhood Hits	96	Shared Neighborhood Hits	21
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.090822 (rank : 74)
Query Neighborhood Hits	443	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB3_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.061788 (rank : 146)
Query Neighborhood Hits	443	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.062170 (rank : 143)
Query Neighborhood Hits	443	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

APC10_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.055002 (rank : 183)
Query Neighborhood Hits	443	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UM13, Q2V500, Q9UG51, Q9Y5R0	Gene names	ANAPC10, APC10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

APC10_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.052749 (rank : 195)
Query Neighborhood Hits	443	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H6, Q9CW24	Gene names	Anapc10, Apc10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

BAG3_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.223180 (rank : 40)
Query Neighborhood Hits	443	Target Neighborhood Hits	314	Shared Neighborhood Hits	48
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.194231 (rank : 45)
Query Neighborhood Hits	443	Target Neighborhood Hits	513	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.062483 (rank : 142)
Query Neighborhood Hits	443	Target Neighborhood Hits	321	Shared Neighborhood Hits	67
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.064878 (rank : 133)
Query Neighborhood Hits	443	Target Neighborhood Hits	260	Shared Neighborhood Hits	55
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CUL7_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.067505 (rank : 123)
Query Neighborhood Hits	443	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

CYLC1_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.052537 (rank : 198)
Query Neighborhood Hits	443	Target Neighborhood Hits	408	Shared Neighborhood Hits	71
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CYLC2_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.054664 (rank : 184)
Query Neighborhood Hits	443	Target Neighborhood Hits	223	Shared Neighborhood Hits	52
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DOC2A_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.056130 (rank : 174)
Query Neighborhood Hits	443	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2A_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.058811 (rank : 161)
Query Neighborhood Hits	443	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.054362 (rank : 188)
Query Neighborhood Hits	443	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.053897 (rank : 190)
Query Neighborhood Hits	443	Target Neighborhood Hits	169	Shared Neighborhood Hits	14
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DRP2_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.057530 (rank : 168)
Query Neighborhood Hits	443	Target Neighborhood Hits	186	Shared Neighborhood Hits	28
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

DSPP_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.068922 (rank : 117)
Query Neighborhood Hits	443	Target Neighborhood Hits	491	Shared Neighborhood Hits	98
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ENL_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.056004 (rank : 175)
Query Neighborhood Hits	443	Target Neighborhood Hits	305	Shared Neighborhood Hits	69
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

FA62A_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.067580 (rank : 122)
Query Neighborhood Hits	443	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.078582 (rank : 102)
Query Neighborhood Hits	443	Target Neighborhood Hits	155	Shared Neighborhood Hits	17
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

GAS7_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.143894 (rank : 54)
Query Neighborhood Hits	443	Target Neighborhood Hits	258	Shared Neighborhood Hits	32
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.141568 (rank : 55)
Query Neighborhood Hits	443	Target Neighborhood Hits	259	Shared Neighborhood Hits	31
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

HTSF1_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.052936 (rank : 194)
Query Neighborhood Hits	443	Target Neighborhood Hits	425	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

K1333_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.064511 (rank : 136)
Query Neighborhood Hits	443	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

MAGI1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.149939 (rank : 53)
Query Neighborhood Hits	443	Target Neighborhood Hits	388	Shared Neighborhood Hits	40
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.150452 (rank : 52)
Query Neighborhood Hits	443	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.152270 (rank : 51)
Query Neighborhood Hits	443	Target Neighborhood Hits	373	Shared Neighborhood Hits	42
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.159668 (rank : 50)
Query Neighborhood Hits	443	Target Neighborhood Hits	370	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAP1B_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.060878 (rank : 151)
Query Neighborhood Hits	443	Target Neighborhood Hits	903	Shared Neighborhood Hits	132
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYCB2_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.059578 (rank : 158)
Query Neighborhood Hits	443	Target Neighborhood Hits	390	Shared Neighborhood Hits	49
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.054549 (rank : 187)
Query Neighborhood Hits	443	Target Neighborhood Hits	307	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NEUM_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.055305 (rank : 178)
Query Neighborhood Hits	443	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NOLC1_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.061118 (rank : 150)
Query Neighborhood Hits	443	Target Neighborhood Hits	452	Shared Neighborhood Hits	85
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NSBP1_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.080090 (rank : 99)
Query Neighborhood Hits	443	Target Neighborhood Hits	251	Shared Neighborhood Hits	70
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NUCKS_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.056331 (rank : 173)
Query Neighborhood Hits	443	Target Neighborhood Hits	143	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.050375 (rank : 212)
Query Neighborhood Hits	443	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

PA24B_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.053627 (rank : 192)
Query Neighborhood Hits	443	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PARC_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.050942 (rank : 206)
Query Neighborhood Hits	443	Target Neighborhood Hits	148	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.055206 (rank : 179)
Query Neighborhood Hits	443	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PELP1_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.059158 (rank : 160)
Query Neighborhood Hits	443	Target Neighborhood Hits	596	Shared Neighborhood Hits	104
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.050422 (rank : 211)
Query Neighborhood Hits	443	Target Neighborhood Hits	709	Shared Neighborhood Hits	113
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PIN1_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.220794 (rank : 41)
Query Neighborhood Hits	443	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.219260 (rank : 42)
Query Neighborhood Hits	443	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PINL_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.262364 (rank : 37)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

PKHA5_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.168795 (rank : 49)
Query Neighborhood Hits	443	Target Neighborhood Hits	455	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PRG4_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.056384 (rank : 172)
Query Neighborhood Hits	443	Target Neighborhood Hits	624	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP40_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.136146 (rank : 57)
Query Neighborhood Hits	443	Target Neighborhood Hits	442	Shared Neighborhood Hits	57
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.136468 (rank : 56)
Query Neighborhood Hits	443	Target Neighborhood Hits	447	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PTMA_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.082825 (rank : 93)
Query Neighborhood Hits	443	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.082321 (rank : 94)
Query Neighborhood Hits	443	Target Neighborhood Hits	73	Shared Neighborhood Hits	36
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.054656 (rank : 185)
Query Neighborhood Hits	443	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.058408 (rank : 162)
Query Neighborhood Hits	443	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

RASL1_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.064476 (rank : 137)
Query Neighborhood Hits	443	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.060830 (rank : 153)
Query Neighborhood Hits	443	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL2_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.057890 (rank : 165)
Query Neighborhood Hits	443	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RCBT1_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.064861 (rank : 134)
Query Neighborhood Hits	443	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

RCBT1_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.066562 (rank : 124)
Query Neighborhood Hits	443	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

RCBT2_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.072021 (rank : 112)
Query Neighborhood Hits	443	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

RCBT2_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.073202 (rank : 109)
Query Neighborhood Hits	443	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

RCC1_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.087768 (rank : 83)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

RCC1_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.085606 (rank : 87)
Query Neighborhood Hits	443	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

RCC2_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.090197 (rank : 78)
Query Neighborhood Hits	443	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

RCC2_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.089459 (rank : 80)
Query Neighborhood Hits	443	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

RHG12_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.059789 (rank : 157)
Query Neighborhood Hits	443	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.068573 (rank : 118)
Query Neighborhood Hits	443	Target Neighborhood Hits	204	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RIMS2_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.053076 (rank : 193)
Query Neighborhood Hits	443	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.052129 (rank : 199)
Query Neighborhood Hits	443	Target Neighborhood Hits	376	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RP1L1_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.058095 (rank : 164)
Query Neighborhood Hits	443	Target Neighborhood Hits	1072	Shared Neighborhood Hits	150
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RPGR_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.100493 (rank : 64)
Query Neighborhood Hits	443	Target Neighborhood Hits	281	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

SAV1_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.281482 (rank : 36)
Query Neighborhood Hits	443	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.281502 (rank : 35)
Query Neighborhood Hits	443	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SETD2_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.089088 (rank : 81)
Query Neighborhood Hits	443	Target Neighborhood Hits	412	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SFR11_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.050455 (rank : 210)
Query Neighborhood Hits	443	Target Neighborhood Hits	246	Shared Neighborhood Hits	41
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SRGEF_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.094788 (rank : 68)
Query Neighborhood Hits	443	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SRGEF_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.091612 (rank : 71)
Query Neighborhood Hits	443	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SRRM1_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.054623 (rank : 186)
Query Neighborhood Hits	443	Target Neighborhood Hits	690	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.051031 (rank : 205)
Query Neighborhood Hits	443	Target Neighborhood Hits	966	Shared Neighborhood Hits	113
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.065279 (rank : 129)
Query Neighborhood Hits	443	Target Neighborhood Hits	1296	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.060614 (rank : 155)
Query Neighborhood Hits	443	Target Neighborhood Hits	1470	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STXB4_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.091871 (rank : 70)
Query Neighborhood Hits	443	Target Neighborhood Hits	616	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.090882 (rank : 73)
Query Neighborhood Hits	443	Target Neighborhood Hits	629	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

T2FA_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.057421 (rank : 169)
Query Neighborhood Hits	443	Target Neighborhood Hits	228	Shared Neighborhood Hits	64
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.065914 (rank : 126)
Query Neighborhood Hits	443	Target Neighborhood Hits	471	Shared Neighborhood Hits	91
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.061775 (rank : 147)
Query Neighborhood Hits	443	Target Neighborhood Hits	929	Shared Neighborhood Hits	100
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.062026 (rank : 145)
Query Neighborhood Hits	443	Target Neighborhood Hits	947	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TOLIP_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.054265 (rank : 189)
Query Neighborhood Hits	443	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

TOLIP_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.056621 (rank : 171)
Query Neighborhood Hits	443	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

UN13A_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.083595 (rank : 92)
Query Neighborhood Hits	443	Target Neighborhood Hits	285	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.074487 (rank : 106)
Query Neighborhood Hits	443	Target Neighborhood Hits	217	Shared Neighborhood Hits	16
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.074322 (rank : 107)
Query Neighborhood Hits	443	Target Neighborhood Hits	210	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13D_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.051295 (rank : 204)
Query Neighborhood Hits	443	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

VCX1_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.057585 (rank : 167)
Query Neighborhood Hits	443	Target Neighborhood Hits	129	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.064298 (rank : 138)
Query Neighborhood Hits	443	Target Neighborhood Hits	105	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.064121 (rank : 140)
Query Neighborhood Hits	443	Target Neighborhood Hits	139	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

WBP4_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.065785 (rank : 128)
Query Neighborhood Hits	443	Target Neighborhood Hits	100	Shared Neighborhood Hits	25
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WBS16_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.082101 (rank : 95)
Query Neighborhood Hits	443	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

WBS16_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.083722 (rank : 90)
Query Neighborhood Hits	443	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

WWC1_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.239833 (rank : 38)
Query Neighborhood Hits	443	Target Neighborhood Hits	290	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.239322 (rank : 39)
Query Neighborhood Hits	443	Target Neighborhood Hits	290	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWOX_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.218288 (rank : 43)
Query Neighborhood Hits	443	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	θ > 10 (rank : 549)	NC score	0.216374 (rank : 44)
Query Neighborhood Hits	443	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

WWTR1_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.188497 (rank : 47)
Query Neighborhood Hits	443	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.191052 (rank : 46)
Query Neighborhood Hits	443	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

YAP1_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.185676 (rank : 48)
Query Neighborhood Hits	443	Target Neighborhood Hits	173	Shared Neighborhood Hits	37
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YAP1_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.313070 (rank : 34)
Query Neighborhood Hits	443	Target Neighborhood Hits	96	Shared Neighborhood Hits	26
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YTDC1_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.051532 (rank : 202)
Query Neighborhood Hits	443	Target Neighborhood Hits	458	Shared Neighborhood Hits	97
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

Hits sorted by NC score

HUWE1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	443	Target Neighborhood Hits	443	Shared Neighborhood Hits	443
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
NC score	0.989016 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	443	Target Neighborhood Hits	406	Shared Neighborhood Hits	300
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

SMUF1_HUMAN
NC score	0.881173 (rank : 3)	θ value	2.46618e-90 (rank : 11)
Query Neighborhood Hits	443	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
NC score	0.878185 (rank : 4)	θ value	4.96919e-91 (rank : 9)
Query Neighborhood Hits	443	Target Neighborhood Hits	142	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

HECD2_MOUSE
NC score	0.877258 (rank : 5)	θ value	7.75577e-52 (rank : 20)
Query Neighborhood Hits	443	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

K0317_HUMAN
NC score	0.877158 (rank : 6)	θ value	2.41096e-53 (rank : 17)
Query Neighborhood Hits	443	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.877116 (rank : 7)	θ value	1.84601e-53 (rank : 16)
Query Neighborhood Hits	443	Target Neighborhood Hits	43	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

SMUF2_HUMAN
NC score	0.876754 (rank : 8)	θ value	4.96919e-91 (rank : 10)
Query Neighborhood Hits	443	Target Neighborhood Hits	142	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

HECD2_HUMAN
NC score	0.875007 (rank : 9)	θ value	7.75577e-52 (rank : 19)
Query Neighborhood Hits	443	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

ITCH_MOUSE
NC score	0.874064 (rank : 10)	θ value	5.30912e-93 (rank : 6)
Query Neighborhood Hits	443	Target Neighborhood Hits	127	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

UBE3A_HUMAN
NC score	0.873705 (rank : 11)	θ value	2.66562e-52 (rank : 18)
Query Neighborhood Hits	443	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
NC score	0.868769 (rank : 12)	θ value	6.14528e-49 (rank : 21)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

WWP2_MOUSE
NC score	0.868436 (rank : 13)	θ value	1.14559e-87 (rank : 15)
Query Neighborhood Hits	443	Target Neighborhood Hits	118	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

WWP2_HUMAN
NC score	0.867338 (rank : 14)	θ value	1.14559e-87 (rank : 14)
Query Neighborhood Hits	443	Target Neighborhood Hits	177	Shared Neighborhood Hits	50
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ITCH_HUMAN
NC score	0.867007 (rank : 15)	θ value	3.44127e-92 (rank : 8)
Query Neighborhood Hits	443	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

WWP1_MOUSE
NC score	0.866793 (rank : 16)	θ value	7.93343e-89 (rank : 13)
Query Neighborhood Hits	443	Target Neighborhood Hits	138	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP1_HUMAN
NC score	0.863292 (rank : 17)	θ value	7.93343e-89 (rank : 12)
Query Neighborhood Hits	443	Target Neighborhood Hits	262	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

UBE3C_HUMAN
NC score	0.862853 (rank : 18)	θ value	1.51363e-47 (rank : 22)
Query Neighborhood Hits	443	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
NC score	0.861519 (rank : 19)	θ value	9.81109e-47 (rank : 23)
Query Neighborhood Hits	443	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

NEDD4_MOUSE
NC score	0.830141 (rank : 20)	θ value	2.63489e-92 (rank : 7)
Query Neighborhood Hits	443	Target Neighborhood Hits	212	Shared Neighborhood Hits	41
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NEDD4_HUMAN
NC score	0.823868 (rank : 21)	θ value	4.06505e-93 (rank : 5)
Query Neighborhood Hits	443	Target Neighborhood Hits	214	Shared Neighborhood Hits	38
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NED4L_MOUSE
NC score	0.810169 (rank : 22)	θ value	2.81514e-94 (rank : 4)
Query Neighborhood Hits	443	Target Neighborhood Hits	231	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
NC score	0.808996 (rank : 23)	θ value	2.81514e-94 (rank : 3)
Query Neighborhood Hits	443	Target Neighborhood Hits	238	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

TRIPC_HUMAN
NC score	0.794785 (rank : 24)	θ value	4.14116e-29 (rank : 27)
Query Neighborhood Hits	443	Target Neighborhood Hits	319	Shared Neighborhood Hits	69
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HECD3_MOUSE
NC score	0.728370 (rank : 25)	θ value	4.73814e-25 (rank : 31)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
NC score	0.724450 (rank : 26)	θ value	1.37858e-24 (rank : 32)
Query Neighborhood Hits	443	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC3_HUMAN
NC score	0.721890 (rank : 27)	θ value	5.21438e-40 (rank : 24)
Query Neighborhood Hits	443	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
NC score	0.718453 (rank : 28)	θ value	3.87602e-27 (rank : 28)
Query Neighborhood Hits	443	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

EDD1_MOUSE
NC score	0.699896 (rank : 29)	θ value	1.62847e-25 (rank : 30)
Query Neighborhood Hits	443	Target Neighborhood Hits	167	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
NC score	0.698365 (rank : 30)	θ value	1.62847e-25 (rank : 29)
Query Neighborhood Hits	443	Target Neighborhood Hits	170	Shared Neighborhood Hits	55
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HERC2_MOUSE
NC score	0.625012 (rank : 31)	θ value	1.52067e-31 (rank : 25)
Query Neighborhood Hits	443	Target Neighborhood Hits	167	Shared Neighborhood Hits	41
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.620820 (rank : 32)	θ value	5.77852e-31 (rank : 26)
Query Neighborhood Hits	443	Target Neighborhood Hits	163	Shared Neighborhood Hits	41
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HECD1_HUMAN
NC score	0.556768 (rank : 33)	θ value	2.06002e-20 (rank : 33)
Query Neighborhood Hits	443	Target Neighborhood Hits	371	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

YAP1_MOUSE
NC score	0.313070 (rank : 34)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	443	Target Neighborhood Hits	96	Shared Neighborhood Hits	26
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

SAV1_MOUSE
NC score	0.281502 (rank : 35)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	443	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SAV1_HUMAN
NC score	0.281482 (rank : 36)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	443	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

PINL_HUMAN
NC score	0.262364 (rank : 37)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

WWC1_HUMAN
NC score	0.239833 (rank : 38)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	443	Target Neighborhood Hits	290	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
NC score	0.239322 (rank : 39)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	443	Target Neighborhood Hits	290	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

BAG3_HUMAN
NC score	0.223180 (rank : 40)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	443	Target Neighborhood Hits	314	Shared Neighborhood Hits	48
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

PIN1_HUMAN
NC score	0.220794 (rank : 41)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	443	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
NC score	0.219260 (rank : 42)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	443	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

WWOX_HUMAN
NC score	0.218288 (rank : 43)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	443	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
NC score	0.216374 (rank : 44)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	443	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

BAG3_MOUSE
NC score	0.194231 (rank : 45)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	443	Target Neighborhood Hits	513	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

WWTR1_MOUSE
NC score	0.191052 (rank : 46)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	443	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_HUMAN
NC score	0.188497 (rank : 47)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	443	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

YAP1_HUMAN
NC score	0.185676 (rank : 48)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	443	Target Neighborhood Hits	173	Shared Neighborhood Hits	37
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PKHA5_HUMAN
NC score	0.168795 (rank : 49)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	443	Target Neighborhood Hits	455	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

MAGI2_MOUSE
NC score	0.159668 (rank : 50)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	443	Target Neighborhood Hits	370	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
NC score	0.152270 (rank : 51)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	443	Target Neighborhood Hits	373	Shared Neighborhood Hits	42
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI1_MOUSE
NC score	0.150452 (rank : 52)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	443	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
NC score	0.149939 (rank : 53)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	443	Target Neighborhood Hits	388	Shared Neighborhood Hits	40
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

GAS7_HUMAN
NC score	0.143894 (rank : 54)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	443	Target Neighborhood Hits	258	Shared Neighborhood Hits	32
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
NC score	0.141568 (rank : 55)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	443	Target Neighborhood Hits	259	Shared Neighborhood Hits	31
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

PRP40_MOUSE
NC score	0.136468 (rank : 56)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	443	Target Neighborhood Hits	447	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PRP40_HUMAN
NC score	0.136146 (rank : 57)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	443	Target Neighborhood Hits	442	Shared Neighborhood Hits	57
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RPGR_HUMAN
NC score	0.119948 (rank : 58)	θ value	0.0252991 (rank : 62)
Query Neighborhood Hits	443	Target Neighborhood Hits	279	Shared Neighborhood Hits	43
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

AKA12_HUMAN
NC score	0.115667 (rank : 59)	θ value	0.000602161 (rank : 38)
Query Neighborhood Hits	443	Target Neighborhood Hits	825	Shared Neighborhood Hits	127
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

LEO1_HUMAN
NC score	0.109238 (rank : 60)	θ value	6.43352e-06 (rank : 34)
Query Neighborhood Hits	443	Target Neighborhood Hits	958	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
NC score	0.106025 (rank : 61)	θ value	8.40245e-06 (rank : 36)
Query Neighborhood Hits	443	Target Neighborhood Hits	946	Shared Neighborhood Hits	119
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NSBP1_MOUSE
NC score	0.102568 (rank : 62)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	443	Target Neighborhood Hits	681	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

BSCL2_HUMAN
NC score	0.101893 (rank : 63)	θ value	0.00665767 (rank : 47)
Query Neighborhood Hits	443	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

RPGR_MOUSE
NC score	0.100493 (rank : 64)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	443	Target Neighborhood Hits	281	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

TXND2_HUMAN
NC score	0.098686 (rank : 65)	θ value	0.00020696 (rank : 37)
Query Neighborhood Hits	443	Target Neighborhood Hits	793	Shared Neighborhood Hits	113
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

DMP1_HUMAN
NC score	0.095939 (rank : 66)	θ value	0.813845 (rank : 143)
Query Neighborhood Hits	443	Target Neighborhood Hits	491	Shared Neighborhood Hits	105
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

CN155_HUMAN
NC score	0.095130 (rank : 67)	θ value	0.0961366 (rank : 81)
Query Neighborhood Hits	443	Target Neighborhood Hits	385	Shared Neighborhood Hits	72
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

SRGEF_HUMAN
NC score	0.094788 (rank : 68)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	443	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

APBB2_HUMAN
NC score	0.093857 (rank : 69)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	443	Target Neighborhood Hits	96	Shared Neighborhood Hits	21
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

STXB4_HUMAN
NC score	0.091871 (rank : 70)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	443	Target Neighborhood Hits	616	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SRGEF_MOUSE
NC score	0.091612 (rank : 71)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	443	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

IWS1_MOUSE
NC score	0.091264 (rank : 72)	θ value	0.00390308 (rank : 41)
Query Neighborhood Hits	443	Target Neighborhood Hits	1258	Shared Neighborhood Hits	154
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

STXB4_MOUSE
NC score	0.090882 (rank : 73)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	443	Target Neighborhood Hits	629	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

APBB2_MOUSE
NC score	0.090822 (rank : 74)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	443	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

TGON2_HUMAN
NC score	0.090504 (rank : 75)	θ value	0.125558 (rank : 91)
Query Neighborhood Hits	443	Target Neighborhood Hits	1037	Shared Neighborhood Hits	137
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

DSPP_HUMAN
NC score	0.090397 (rank : 76)	θ value	0.0563607 (rank : 74)
Query Neighborhood Hits	443	Target Neighborhood Hits	645	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SGP50_MOUSE
NC score	0.090256 (rank : 77)	θ value	0.21417 (rank : 107)
Query Neighborhood Hits	443	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q02596	Gene names	Glycam1
Domain Architecture
Description	Sulfated 50 kDa glycoprotein precursor (SGP50) (Endothelial ligand FOR L-selectin) (Glycosylation-dependent cell adhesion molecule 1) (GlyCAM-1) (MC26).

RCC2_HUMAN
NC score	0.090197 (rank : 78)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	443	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

PCLO_HUMAN
NC score	0.089930 (rank : 79)	θ value	0.813845 (rank : 150)
Query Neighborhood Hits	443	Target Neighborhood Hits	2046	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RCC2_MOUSE
NC score	0.089459 (rank : 80)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	443	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

SETD2_HUMAN
NC score	0.089088 (rank : 81)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	443	Target Neighborhood Hits	412	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

ERIC1_HUMAN
NC score	0.087930 (rank : 82)	θ value	0.0252991 (rank : 59)
Query Neighborhood Hits	443	Target Neighborhood Hits	364	Shared Neighborhood Hits	59
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

RCC1_HUMAN
NC score	0.087768 (rank : 83)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

TXND2_MOUSE
NC score	0.086526 (rank : 84)	θ value	0.00509761 (rank : 46)
Query Neighborhood Hits	443	Target Neighborhood Hits	828	Shared Neighborhood Hits	99
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

MUC7_HUMAN
NC score	0.086370 (rank : 85)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	443	Target Neighborhood Hits	538	Shared Neighborhood Hits	96
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

IWS1_HUMAN
NC score	0.086193 (rank : 86)	θ value	0.0252991 (rank : 60)
Query Neighborhood Hits	443	Target Neighborhood Hits	1241	Shared Neighborhood Hits	149
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RCC1_MOUSE
NC score	0.085606 (rank : 87)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	443	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

MUC1_MOUSE
NC score	0.084092 (rank : 88)	θ value	0.279714 (rank : 109)
Query Neighborhood Hits	443	Target Neighborhood Hits	388	Shared Neighborhood Hits	80
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PRG4_HUMAN
NC score	0.083755 (rank : 89)	θ value	0.0563607 (rank : 75)
Query Neighborhood Hits	443	Target Neighborhood Hits	764	Shared Neighborhood Hits	127
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WBS16_MOUSE
NC score	0.083722 (rank : 90)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	443	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

DMP1_MOUSE
NC score	0.083721 (rank : 91)	θ value	6.88961 (rank : 351)
Query Neighborhood Hits	443	Target Neighborhood Hits	498	Shared Neighborhood Hits	116
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

UN13A_HUMAN
NC score	0.083595 (rank : 92)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	443	Target Neighborhood Hits	285	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

PTMA_HUMAN
NC score	0.082825 (rank : 93)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	443	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
NC score	0.082321 (rank : 94)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	443	Target Neighborhood Hits	73	Shared Neighborhood Hits	36
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

WBS16_HUMAN
NC score	0.082101 (rank : 95)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	443	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

PCLO_MOUSE
NC score	0.081989 (rank : 96)	θ value	1.81305 (rank : 199)
Query Neighborhood Hits	443	Target Neighborhood Hits	2275	Shared Neighborhood Hits	181
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NACAM_MOUSE
NC score	0.081685 (rank : 97)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	443	Target Neighborhood Hits	1866	Shared Neighborhood Hits	175
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TP53B_HUMAN
NC score	0.080330 (rank : 98)	θ value	0.0330416 (rank : 68)
Query Neighborhood Hits	443	Target Neighborhood Hits	413	Shared Neighborhood Hits	79
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

NSBP1_HUMAN
NC score	0.080090 (rank : 99)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	443	Target Neighborhood Hits	251	Shared Neighborhood Hits	70
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NU214_HUMAN
NC score	0.079701 (rank : 100)	θ value	0.0961366 (rank : 84)
Query Neighborhood Hits	443	Target Neighborhood Hits	657	Shared Neighborhood Hits	83
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MATR3_MOUSE
NC score	0.079039 (rank : 101)	θ value	0.0148317 (rank : 53)
Query Neighborhood Hits	443	Target Neighborhood Hits	321	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

FA62A_MOUSE
NC score	0.078582 (rank : 102)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	443	Target Neighborhood Hits	155	Shared Neighborhood Hits	17
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

RTN4_HUMAN
NC score	0.078063 (rank : 103)	θ value	0.00509761 (rank : 45)
Query Neighborhood Hits	443	Target Neighborhood Hits	357	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

BRD8_MOUSE
NC score	0.075053 (rank : 104)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	443	Target Neighborhood Hits	422	Shared Neighborhood Hits	57
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

SET1A_HUMAN
NC score	0.074959 (rank : 105)	θ value	0.163984 (rank : 101)
Query Neighborhood Hits	443	Target Neighborhood Hits	690	Shared Neighborhood Hits	116
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

UN13B_HUMAN
NC score	0.074487 (rank : 106)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	443	Target Neighborhood Hits	217	Shared Neighborhood Hits	16
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
NC score	0.074322 (rank : 107)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	443	Target Neighborhood Hits	210	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

MDC1_HUMAN
NC score	0.074083 (rank : 108)	θ value	0.0193708 (rank : 56)
Query Neighborhood Hits	443	Target Neighborhood Hits	1446	Shared Neighborhood Hits	159
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RCBT2_MOUSE
NC score	0.073202 (rank : 109)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	443	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

MUC13_MOUSE
NC score	0.072557 (rank : 110)	θ value	0.21417 (rank : 106)
Query Neighborhood Hits	443	Target Neighborhood Hits	447	Shared Neighborhood Hits	63
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

TCOF_HUMAN
NC score	0.072240 (rank : 111)	θ value	5.27518 (rank : 338)
Query Neighborhood Hits	443	Target Neighborhood Hits	543	Shared Neighborhood Hits	108
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

RCBT2_HUMAN
NC score	0.072021 (rank : 112)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	443	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

ASPH_HUMAN
NC score	0.071867 (rank : 113)	θ value	0.0961366 (rank : 80)
Query Neighborhood Hits	443	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

NASP_HUMAN
NC score	0.071618 (rank : 114)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	443	Target Neighborhood Hits	709	Shared Neighborhood Hits	104
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

TP53B_MOUSE
NC score	0.071424 (rank : 115)	θ value	0.47712 (rank : 124)
Query Neighborhood Hits	443	Target Neighborhood Hits	644	Shared Neighborhood Hits	95
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TCAL5_HUMAN
NC score	0.069027 (rank : 116)	θ value	0.00228821 (rank : 40)
Query Neighborhood Hits	443	Target Neighborhood Hits	806	Shared Neighborhood Hits	95
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

DSPP_MOUSE
NC score	0.068922 (rank : 117)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	443	Target Neighborhood Hits	491	Shared Neighborhood Hits	98
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RHG12_MOUSE
NC score	0.068573 (rank : 118)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	443	Target Neighborhood Hits	204	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RTN4_MOUSE
NC score	0.068272 (rank : 119)	θ value	0.00390308 (rank : 42)
Query Neighborhood Hits	443	Target Neighborhood Hits	341	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

NCOR2_HUMAN
NC score	0.067697 (rank : 120)	θ value	0.0113563 (rank : 50)
Query Neighborhood Hits	443	Target Neighborhood Hits	870	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TF2AY_MOUSE
NC score	0.067672 (rank : 121)	θ value	0.0330416 (rank : 67)
Query Neighborhood Hits	443	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4I4, Q99PM2, Q9DAF4	Gene names	Gtf2a1lf, Alf
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

FA62A_HUMAN
NC score	0.067580 (rank : 122)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	443	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

CUL7_HUMAN
NC score	0.067505 (rank : 123)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	443	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

RCBT1_MOUSE
NC score	0.066562 (rank : 124)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	443	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

CC47_MOUSE
NC score	0.066557 (rank : 125)	θ value	0.0252991 (rank : 58)
Query Neighborhood Hits	443	Target Neighborhood Hits	245	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

TCOF_MOUSE
NC score	0.065914 (rank : 126)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	443	Target Neighborhood Hits	471	Shared Neighborhood Hits	91
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

VPS72_MOUSE
NC score	0.065913 (rank : 127)	θ value	0.279714 (rank : 112)
Query Neighborhood Hits	443	Target Neighborhood Hits	286	Shared Neighborhood Hits	37
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

WBP4_MOUSE
NC score	0.065785 (rank : 128)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	443	Target Neighborhood Hits	100	Shared Neighborhood Hits	25
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

SRRM2_HUMAN
NC score	0.065279 (rank : 129)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	443	Target Neighborhood Hits	1296	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CK024_MOUSE
NC score	0.065195 (rank : 130)	θ value	1.38821 (rank : 171)
Query Neighborhood Hits	443	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

MAP1B_MOUSE
NC score	0.065075 (rank : 131)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	443	Target Neighborhood Hits	977	Shared Neighborhood Hits	139
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAGE1_HUMAN
NC score	0.064979 (rank : 132)	θ value	0.0193708 (rank : 55)
Query Neighborhood Hits	443	Target Neighborhood Hits	1389	Shared Neighborhood Hits	138
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BASP_MOUSE
NC score	0.064878 (rank : 133)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	443	Target Neighborhood Hits	260	Shared Neighborhood Hits	55
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

RCBT1_HUMAN
NC score	0.064861 (rank : 134)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	443	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

MATR3_HUMAN
NC score	0.064806 (rank : 135)	θ value	0.163984 (rank : 96)
Query Neighborhood Hits	443	Target Neighborhood Hits	325	Shared Neighborhood Hits	51
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

K1333_MOUSE
NC score	0.064511 (rank : 136)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	443	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

RASL1_HUMAN
NC score	0.064476 (rank : 137)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	443	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

VCX3_HUMAN
NC score	0.064298 (rank : 138)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	443	Target Neighborhood Hits	105	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

BSCL2_MOUSE
NC score	0.064152 (rank : 139)	θ value	0.47712 (rank : 120)
Query Neighborhood Hits	443	Target Neighborhood Hits	94	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

VCXC_HUMAN
NC score	0.064121 (rank : 140)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	443	Target Neighborhood Hits	139	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

VPS72_HUMAN
NC score	0.063295 (rank : 141)	θ value	0.279714 (rank : 111)
Query Neighborhood Hits	443	Target Neighborhood Hits	274	Shared Neighborhood Hits	34
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

BASP_HUMAN
NC score	0.062483 (rank : 142)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	443	Target Neighborhood Hits	321	Shared Neighborhood Hits	67
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

APBB3_MOUSE
NC score	0.062170 (rank : 143)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	443	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

REV1_MOUSE
NC score	0.062091 (rank : 144)	θ value	0.0330416 (rank : 66)
Query Neighborhood Hits	443	Target Neighborhood Hits	67	Shared Neighborhood Hits	14
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

TCRG1_MOUSE
NC score	0.062026 (rank : 145)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	443	Target Neighborhood Hits	947	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

APBB3_HUMAN
NC score	0.061788 (rank : 146)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	443	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

TCRG1_HUMAN
NC score	0.061775 (rank : 147)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	443	Target Neighborhood Hits	929	Shared Neighborhood Hits	100
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

NIPBL_HUMAN
NC score	0.061740 (rank : 148)	θ value	0.0148317 (rank : 54)
Query Neighborhood Hits	443	Target Neighborhood Hits	1311	Shared Neighborhood Hits	146
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ATX2_MOUSE
NC score	0.061239 (rank : 149)	θ value	0.0736092 (rank : 76)
Query Neighborhood Hits	443	Target Neighborhood Hits	445	Shared Neighborhood Hits	63
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

NOLC1_HUMAN
NC score	0.061118 (rank : 150)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	443	Target Neighborhood Hits	452	Shared Neighborhood Hits	85
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

MAP1B_HUMAN
NC score	0.060878 (rank : 151)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	443	Target Neighborhood Hits	903	Shared Neighborhood Hits	132
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NFH_MOUSE
NC score	0.060850 (rank : 152)	θ value	6.43352e-06 (rank : 35)
Query Neighborhood Hits	443	Target Neighborhood Hits	2247	Shared Neighborhood Hits	207
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RASL1_MOUSE
NC score	0.060830 (rank : 153)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	443	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

BRD8_HUMAN
NC score	0.060681 (rank : 154)	θ value	0.0330416 (rank : 63)
Query Neighborhood Hits	443	Target Neighborhood Hits	292	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

SRRM2_MOUSE
NC score	0.060614 (rank : 155)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	443	Target Neighborhood Hits	1470	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PODXL_HUMAN
NC score	0.059830 (rank : 156)	θ value	1.06291 (rank : 161)
Query Neighborhood Hits	443	Target Neighborhood Hits	191	Shared Neighborhood Hits	42
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RHG12_HUMAN
NC score	0.059789 (rank : 157)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	443	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

MYCB2_HUMAN
NC score	0.059578 (rank : 158)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	443	Target Neighborhood Hits	390	Shared Neighborhood Hits	49
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TARA_HUMAN
NC score	0.059210 (rank : 159)	θ value	0.0736092 (rank : 79)
Query Neighborhood Hits	443	Target Neighborhood Hits	1626	Shared Neighborhood Hits	140
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PELP1_HUMAN
NC score	0.059158 (rank : 160)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	443	Target Neighborhood Hits	596	Shared Neighborhood Hits	104
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

DOC2A_MOUSE
NC score	0.058811 (rank : 161)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	443	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

PTMS_MOUSE
NC score	0.058408 (rank : 162)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	443	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

NPBL_MOUSE
NC score	0.058162 (rank : 163)	θ value	0.47712 (rank : 123)
Query Neighborhood Hits	443	Target Neighborhood Hits	1041	Shared Neighborhood Hits	119
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RP1L1_HUMAN
NC score	0.058095 (rank : 164)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	443	Target Neighborhood Hits	1072	Shared Neighborhood Hits	150
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RASL2_HUMAN
NC score	0.057890 (rank : 165)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	443	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

PERP_MOUSE
NC score	0.057789 (rank : 166)	θ value	0.163984 (rank : 99)
Query Neighborhood Hits	443	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JK95, Q9JI77	Gene names	Perp, Krtcap1
Domain Architecture	No domain graphic available
Description	p53 apoptosis effector related to PMP-22 (Keratinocytes-associated protein 1) (KCP-1).

VCX1_HUMAN
NC score	0.057585 (rank : 167)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	443	Target Neighborhood Hits	129	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

DRP2_HUMAN
NC score	0.057530 (rank : 168)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	443	Target Neighborhood Hits	186	Shared Neighborhood Hits	28
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

T2FA_HUMAN
NC score	0.057421 (rank : 169)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	443	Target Neighborhood Hits	228	Shared Neighborhood Hits	64
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

ALS2_HUMAN
NC score	0.056883 (rank : 170)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	443	Target Neighborhood Hits	121	Shared Neighborhood Hits	10
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

TOLIP_MOUSE
NC score	0.056621 (rank : 171)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	443	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

PRG4_MOUSE
NC score	0.056384 (rank : 172)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	443	Target Neighborhood Hits	624	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

NUCKS_HUMAN
NC score	0.056331 (rank : 173)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	443	Target Neighborhood Hits	143	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

DOC2A_HUMAN
NC score	0.056130 (rank : 174)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	443	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

ENL_HUMAN
NC score	0.056004 (rank : 175)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	443	Target Neighborhood Hits	305	Shared Neighborhood Hits	69
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

TGON1_MOUSE
NC score	0.055567 (rank : 176)	θ value	0.62314 (rank : 138)
Query Neighborhood Hits	443	Target Neighborhood Hits	243	Shared Neighborhood Hits	55
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

ALS2_MOUSE
NC score	0.055435 (rank : 177)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	443	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

NEUM_MOUSE
NC score	0.055305 (rank : 178)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	443	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

PARC_MOUSE
NC score	0.055206 (rank : 179)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	443	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

ADDA_MOUSE
NC score	0.055156 (rank : 180)	θ value	0.125558 (rank : 87)
Query Neighborhood Hits	443	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

ZN750_MOUSE
NC score	0.055114 (rank : 181)	θ value	0.0961366 (rank : 86)
Query Neighborhood Hits	443	Target Neighborhood Hits	346	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ATX2_HUMAN
NC score	0.055031 (rank : 182)	θ value	1.38821 (rank : 170)
Query Neighborhood Hits	443	Target Neighborhood Hits	375	Shared Neighborhood Hits	50
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

APC10_HUMAN
NC score	0.055002 (rank : 183)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	443	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UM13, Q2V500, Q9UG51, Q9Y5R0	Gene names	ANAPC10, APC10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

CYLC2_HUMAN
NC score	0.054664 (rank : 184)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	443	Target Neighborhood Hits	223	Shared Neighborhood Hits	52
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

PTMS_HUMAN
NC score	0.054656 (rank : 185)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	443	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

SRRM1_HUMAN
NC score	0.054623 (rank : 186)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	443	Target Neighborhood Hits	690	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MYCB2_MOUSE
NC score	0.054549 (rank : 187)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	443	Target Neighborhood Hits	307	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

DOC2B_HUMAN
NC score	0.054362 (rank : 188)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	443	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

TOLIP_HUMAN
NC score	0.054265 (rank : 189)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	443	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

DOC2B_MOUSE
NC score	0.053897 (rank : 190)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	443	Target Neighborhood Hits	169	Shared Neighborhood Hits	14
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SEC63_HUMAN
NC score	0.053838 (rank : 191)	θ value	0.0431538 (rank : 71)
Query Neighborhood Hits	443	Target Neighborhood Hits	586	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

PA24B_MOUSE
NC score	0.053627 (rank : 192)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	443	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

RIMS2_HUMAN
NC score	0.053076 (rank : 193)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	443	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

HTSF1_MOUSE
NC score	0.052936 (rank : 194)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	443	Target Neighborhood Hits	425	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

APC10_MOUSE
NC score	0.052749 (rank : 195)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	443	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H6, Q9CW24	Gene names	Anapc10, Apc10
Domain Architecture
Description	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10).

MDC1_MOUSE
NC score	0.052626 (rank : 196)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	443	Target Neighborhood Hits	998	Shared Neighborhood Hits	130
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BPTF_HUMAN
NC score	0.052602 (rank : 197)	θ value	0.62314 (rank : 126)
Query Neighborhood Hits	443	Target Neighborhood Hits	786	Shared Neighborhood Hits	120
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CYLC1_HUMAN
NC score	0.052537 (rank : 198)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	443	Target Neighborhood Hits	408	Shared Neighborhood Hits	71
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

RIMS2_MOUSE
NC score	0.052129 (rank : 199)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	443	Target Neighborhood Hits	376	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

K1683_HUMAN
NC score	0.052112 (rank : 200)	θ value	0.0961366 (rank : 83)
Query Neighborhood Hits	443	Target Neighborhood Hits	240	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

ACINU_MOUSE
NC score	0.051841 (rank : 201)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	443	Target Neighborhood Hits	712	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

YTDC1_HUMAN
NC score	0.051532 (rank : 202)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	443	Target Neighborhood Hits	458	Shared Neighborhood Hits	97
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

OGFR_MOUSE
NC score	0.051443 (rank : 203)	θ value	0.365318 (rank : 117)
Query Neighborhood Hits	443	Target Neighborhood Hits	584	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

UN13D_HUMAN
NC score	0.051295 (rank : 204)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	443	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

SRRM1_MOUSE
NC score	0.051031 (rank : 205)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	443	Target Neighborhood Hits	966	Shared Neighborhood Hits	113
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PARC_HUMAN
NC score	0.050942 (rank : 206)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	443	Target Neighborhood Hits	148	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

RSF1_HUMAN
NC score	0.050714 (rank : 207)	θ value	3.0926 (rank : 257)
Query Neighborhood Hits	443	Target Neighborhood Hits	539	Shared Neighborhood Hits	90
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

TCAL3_HUMAN
NC score	0.050575 (rank : 208)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	443	Target Neighborhood Hits	274	Shared Neighborhood Hits	42
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

REV1_HUMAN
NC score	0.050559 (rank : 209)	θ value	0.365318 (rank : 118)
Query Neighborhood Hits	443	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

SFR11_HUMAN
NC score	0.050455 (rank : 210)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	443	Target Neighborhood Hits	246	Shared Neighborhood Hits	41
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

PELP1_MOUSE
NC score	0.050422 (rank : 211)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	443	Target Neighborhood Hits	709	Shared Neighborhood Hits	113
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

NUCKS_MOUSE
NC score	0.050375 (rank : 212)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	443	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

SEC63_MOUSE
NC score	0.049471 (rank : 213)	θ value	0.163984 (rank : 100)
Query Neighborhood Hits	443	Target Neighborhood Hits	601	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

CQ028_MOUSE
NC score	0.049038 (rank : 214)	θ value	0.163984 (rank : 93)
Query Neighborhood Hits	443	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

NCKX1_HUMAN
NC score	0.049037 (rank : 215)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	443	Target Neighborhood Hits	223	Shared Neighborhood Hits	70
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

SRCA_HUMAN
NC score	0.048438 (rank : 216)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	443	Target Neighborhood Hits	380	Shared Neighborhood Hits	90
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

AKAP2_MOUSE
NC score	0.048300 (rank : 217)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	443	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

DCP1A_HUMAN
NC score	0.048091 (rank : 218)	θ value	0.21417 (rank : 103)
Query Neighborhood Hits	443	Target Neighborhood Hits	228	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

MAP1A_HUMAN
NC score	0.047929 (rank : 219)	θ value	1.06291 (rank : 160)
Query Neighborhood Hits	443	Target Neighborhood Hits	1626	Shared Neighborhood Hits	152
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

BSN_HUMAN
NC score	0.047654 (rank : 220)	θ value	1.06291 (rank : 155)
Query Neighborhood Hits	443	Target Neighborhood Hits	1537	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SON_HUMAN
NC score	0.047511 (rank : 221)	θ value	0.125558 (rank : 90)
Query Neighborhood Hits	443	Target Neighborhood Hits	1568	Shared Neighborhood Hits	131
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RAG2_MOUSE
NC score	0.047479 (rank : 222)	θ value	0.279714 (rank : 110)
Query Neighborhood Hits	443	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P21784	Gene names	Rag2, Rag-2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

FBX34_MOUSE
NC score	0.047123 (rank : 223)	θ value	0.163984 (rank : 94)
Query Neighborhood Hits	443	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

RGS3_MOUSE
NC score	0.046916 (rank : 224)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	443	Target Neighborhood Hits	1621	Shared Neighborhood Hits	134
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TF2AY_HUMAN
NC score	0.046773 (rank : 225)	θ value	1.06291 (rank : 162)
Query Neighborhood Hits	443	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UNN4	Gene names	GTF2A1LF, ALF
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

EVI2B_MOUSE
NC score	0.046490 (rank : 226)	θ value	0.0961366 (rank : 82)
Query Neighborhood Hits	443	Target Neighborhood Hits	87	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

SRCA_MOUSE
NC score	0.045509 (rank : 227)	θ value	0.62314 (rank : 135)
Query Neighborhood Hits	443	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SFR12_HUMAN
NC score	0.044526 (rank : 228)	θ value	5.27518 (rank : 333)
Query Neighborhood Hits	443	Target Neighborhood Hits	553	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

CJ012_HUMAN
NC score	0.044169 (rank : 229)	θ value	8.99809 (rank : 393)
Query Neighborhood Hits	443	Target Neighborhood Hits	467	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

OXR1_MOUSE
NC score	0.043017 (rank : 230)	θ value	1.81305 (rank : 197)
Query Neighborhood Hits	443	Target Neighborhood Hits	516	Shared Neighborhood Hits	84
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

HCFC1_HUMAN
NC score	0.042464 (rank : 231)	θ value	0.21417 (rank : 105)
Query Neighborhood Hits	443	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MUC1_HUMAN
NC score	0.042165 (rank : 232)	θ value	0.0193708 (rank : 57)
Query Neighborhood Hits	443	Target Neighborhood Hits	975	Shared Neighborhood Hits	87
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RBBP6_HUMAN
NC score	0.042068 (rank : 233)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	443	Target Neighborhood Hits	1135	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

MYST3_MOUSE
NC score	0.041989 (rank : 234)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	443	Target Neighborhood Hits	688	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

RBM25_HUMAN
NC score	0.041702 (rank : 235)	θ value	0.62314 (rank : 133)
Query Neighborhood Hits	443	Target Neighborhood Hits	682	Shared Neighborhood Hits	70
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

HCFC1_MOUSE
NC score	0.041589 (rank : 236)	θ value	0.163984 (rank : 95)
Query Neighborhood Hits	443	Target Neighborhood Hits	348	Shared Neighborhood Hits	50
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

EMSY_MOUSE
NC score	0.041532 (rank : 237)	θ value	0.813845 (rank : 145)
Query Neighborhood Hits	443	Target Neighborhood Hits	294	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

MLL2_HUMAN
NC score	0.041181 (rank : 238)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	443	Target Neighborhood Hits	1788	Shared Neighborhood Hits	143
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ADDB_MOUSE
NC score	0.041091 (rank : 239)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	443	Target Neighborhood Hits	574	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

POLI_MOUSE
NC score	0.040970 (rank : 240)	θ value	0.62314 (rank : 132)
Query Neighborhood Hits	443	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

POLI_HUMAN
NC score	0.040367 (rank : 241)	θ value	0.62314 (rank : 131)
Query Neighborhood Hits	443	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

AKAP2_HUMAN
NC score	0.039767 (rank : 242)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	443	Target Neighborhood Hits	507	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ETV3_MOUSE
NC score	0.039540 (rank : 243)	θ value	0.00175202 (rank : 39)
Query Neighborhood Hits	443	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

NPM_MOUSE
NC score	0.039361 (rank : 244)	θ value	0.163984 (rank : 98)
Query Neighborhood Hits	443	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q61937	Gene names	Npm1
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

LRRF1_MOUSE
NC score	0.039266 (rank : 245)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	443	Target Neighborhood Hits	440	Shared Neighborhood Hits	55
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

XRCC1_MOUSE
NC score	0.039218 (rank : 246)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	443	Target Neighborhood Hits	242	Shared Neighborhood Hits	45
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

CNOT3_MOUSE
NC score	0.038812 (rank : 247)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	443	Target Neighborhood Hits	504	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DMD_HUMAN
NC score	0.038670 (rank : 248)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	443	Target Neighborhood Hits	1135	Shared Neighborhood Hits	74
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

GP73_MOUSE
NC score	0.038297 (rank : 249)	θ value	1.38821 (rank : 174)
Query Neighborhood Hits	443	Target Neighborhood Hits	506	Shared Neighborhood Hits	53
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

OSBL8_HUMAN
NC score	0.038170 (rank : 250)	θ value	0.0736092 (rank : 78)
Query Neighborhood Hits	443	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

CQ028_HUMAN
NC score	0.038071 (rank : 251)	θ value	1.81305 (rank : 186)
Query Neighborhood Hits	443	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

RTN1_HUMAN
NC score	0.037691 (rank : 252)	θ value	3.0926 (rank : 258)
Query Neighborhood Hits	443	Target Neighborhood Hits	173	Shared Neighborhood Hits	33
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

ASPP1_MOUSE
NC score	0.037256 (rank : 253)	θ value	0.00509761 (rank : 43)
Query Neighborhood Hits	443	Target Neighborhood Hits	1244	Shared Neighborhood Hits	103
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

SAS10_MOUSE
NC score	0.037169 (rank : 254)	θ value	1.81305 (rank : 204)
Query Neighborhood Hits	443	Target Neighborhood Hits	81	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

CCD47_HUMAN
NC score	0.037122 (rank : 255)	θ value	4.03905 (rank : 275)
Query Neighborhood Hits	443	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

SETBP_MOUSE
NC score	0.036663 (rank : 256)	θ value	5.27518 (rank : 332)
Query Neighborhood Hits	443	Target Neighborhood Hits	352	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

BRCA1_MOUSE
NC score	0.036611 (rank : 257)	θ value	0.0736092 (rank : 77)
Query Neighborhood Hits	443	Target Neighborhood Hits	436	Shared Neighborhood Hits	31
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

F10A5_HUMAN
NC score	0.036587 (rank : 258)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	443	Target Neighborhood Hits	277	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

CCD82_HUMAN
NC score	0.036565 (rank : 259)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	443	Target Neighborhood Hits	137	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

F10A1_HUMAN
NC score	0.036399 (rank : 260)	θ value	0.813845 (rank : 146)
Query Neighborhood Hits	443	Target Neighborhood Hits	312	Shared Neighborhood Hits	37
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

DCP1A_MOUSE
NC score	0.036323 (rank : 261)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	443	Target Neighborhood Hits	103	Shared Neighborhood Hits	19
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

SMRC2_MOUSE
NC score	0.036286 (rank : 262)	θ value	1.81305 (rank : 206)
Query Neighborhood Hits	443	Target Neighborhood Hits	487	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

CFDP1_MOUSE
NC score	0.036089 (rank : 263)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	443	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	O88271, O70565, Q9JMA5	Gene names	Cfdp1, Bcnt, Cfdp, Cp27
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur) (27 kDa craniofacial protein) (Protein Cp27).

E2F4_HUMAN
NC score	0.035437 (rank : 264)	θ value	0.47712 (rank : 121)
Query Neighborhood Hits	443	Target Neighborhood Hits	188	Shared Neighborhood Hits	23
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

TXLNB_HUMAN
NC score	0.035169 (rank : 265)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	443	Target Neighborhood Hits	912	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

SETBP_HUMAN
NC score	0.034706 (rank : 266)	θ value	4.03905 (rank : 287)
Query Neighborhood Hits	443	Target Neighborhood Hits	305	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SEC62_HUMAN
NC score	0.034626 (rank : 267)	θ value	6.88961 (rank : 370)
Query Neighborhood Hits	443	Target Neighborhood Hits	100	Shared Neighborhood Hits	26
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

RAG2_HUMAN
NC score	0.034333 (rank : 268)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	443	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	P55895, Q8TBL4	Gene names	RAG2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

CCD82_MOUSE
NC score	0.034219 (rank : 269)	θ value	4.03905 (rank : 276)
Query Neighborhood Hits	443	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PG04, Q3V462	Gene names	Ccdc82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

RHBD3_MOUSE
NC score	0.034176 (rank : 270)	θ value	1.81305 (rank : 202)
Query Neighborhood Hits	443	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BP97, Q3U0Y4, Q5SUT5, Q5SUT6, Q5SUT7	Gene names	Rhbdd3
Domain Architecture	No domain graphic available
Description	Rhomboid domain-containing protein 3.

ZCC2_HUMAN
NC score	0.034142 (rank : 271)	θ value	0.279714 (rank : 113)
Query Neighborhood Hits	443	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

LAD1_HUMAN
NC score	0.033979 (rank : 272)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	443	Target Neighborhood Hits	441	Shared Neighborhood Hits	60
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

CEP35_HUMAN
NC score	0.033793 (rank : 273)	θ value	1.81305 (rank : 184)
Query Neighborhood Hits	443	Target Neighborhood Hits	811	Shared Neighborhood Hits	80
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

K0141_MOUSE
NC score	0.032900 (rank : 274)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	443	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DCV6, Q6A0B8	Gene names	Kiaa0141
Domain Architecture
Description	Protein KIAA0141.

ANLN_MOUSE
NC score	0.032645 (rank : 275)	θ value	1.06291 (rank : 153)
Query Neighborhood Hits	443	Target Neighborhood Hits	297	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

SYTL5_MOUSE
NC score	0.031962 (rank : 276)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	443	Target Neighborhood Hits	154	Shared Neighborhood Hits	14
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

ZC11A_MOUSE
NC score	0.031961 (rank : 277)	θ value	1.81305 (rank : 211)
Query Neighborhood Hits	443	Target Neighborhood Hits	216	Shared Neighborhood Hits	34
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

INCE_HUMAN
NC score	0.031566 (rank : 278)	θ value	0.47712 (rank : 122)
Query Neighborhood Hits	443	Target Neighborhood Hits	978	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

TDRD5_HUMAN
NC score	0.031372 (rank : 279)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	443	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

SMRC1_MOUSE
NC score	0.031166 (rank : 280)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	443	Target Neighborhood Hits	459	Shared Neighborhood Hits	79
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

CIC_HUMAN
NC score	0.031041 (rank : 281)	θ value	0.813845 (rank : 142)
Query Neighborhood Hits	443	Target Neighborhood Hits	992	Shared Neighborhood Hits	94
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SYNJ1_MOUSE
NC score	0.030930 (rank : 282)	θ value	5.27518 (rank : 336)
Query Neighborhood Hits	443	Target Neighborhood Hits	516	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

RPTN_MOUSE
NC score	0.030811 (rank : 283)	θ value	1.81305 (rank : 203)
Query Neighborhood Hits	443	Target Neighborhood Hits	650	Shared Neighborhood Hits	62
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SF3B1_HUMAN
NC score	0.030698 (rank : 284)	θ value	0.62314 (rank : 134)
Query Neighborhood Hits	443	Target Neighborhood Hits	341	Shared Neighborhood Hits	31
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

NALP5_MOUSE
NC score	0.030688 (rank : 285)	θ value	0.365318 (rank : 115)
Query Neighborhood Hits	443	Target Neighborhood Hits	560	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

SEMG1_HUMAN
NC score	0.030181 (rank : 286)	θ value	3.0926 (rank : 259)
Query Neighborhood Hits	443	Target Neighborhood Hits	200	Shared Neighborhood Hits	27
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

THUM1_HUMAN
NC score	0.029957 (rank : 287)	θ value	2.36792 (rank : 227)
Query Neighborhood Hits	443	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NXG2, Q9BWC3	Gene names	THUMPD1
Domain Architecture
Description	THUMP domain-containing protein 1.

ATRX_HUMAN
NC score	0.029891 (rank : 288)	θ value	8.99809 (rank : 386)
Query Neighborhood Hits	443	Target Neighborhood Hits	842	Shared Neighborhood Hits	104
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

MUCDL_HUMAN
NC score	0.029735 (rank : 289)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	443	Target Neighborhood Hits	777	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NSD1_MOUSE
NC score	0.029618 (rank : 290)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	443	Target Neighborhood Hits	472	Shared Neighborhood Hits	59
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

LARP1_HUMAN
NC score	0.029602 (rank : 291)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	443	Target Neighborhood Hits	242	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

MILK1_MOUSE
NC score	0.029523 (rank : 292)	θ value	6.88961 (rank : 366)
Query Neighborhood Hits	443	Target Neighborhood Hits	788	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NCOA6_MOUSE
NC score	0.029457 (rank : 293)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	443	Target Neighborhood Hits	1076	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ESCO1_HUMAN
NC score	0.029138 (rank : 294)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	443	Target Neighborhood Hits	361	Shared Neighborhood Hits	55
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

RTP3_MOUSE
NC score	0.029111 (rank : 295)	θ value	5.27518 (rank : 330)
Query Neighborhood Hits	443	Target Neighborhood Hits	374	Shared Neighborhood Hits	48
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

MAML2_HUMAN
NC score	0.028880 (rank : 296)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	443	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

APC_HUMAN
NC score	0.028764 (rank : 297)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	443	Target Neighborhood Hits	603	Shared Neighborhood Hits	85
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

EMSY_HUMAN
NC score	0.028717 (rank : 298)	θ value	4.03905 (rank : 278)
Query Neighborhood Hits	443	Target Neighborhood Hits	296	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

BIN1_HUMAN
NC score	0.028560 (rank : 299)	θ value	8.99809 (rank : 387)
Query Neighborhood Hits	443	Target Neighborhood Hits	335	Shared Neighborhood Hits	48
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

ANK2_HUMAN
NC score	0.028426 (rank : 300)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	443	Target Neighborhood Hits	1615	Shared Neighborhood Hits	170
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

DMXL2_HUMAN
NC score	0.028247 (rank : 301)	θ value	0.0563607 (rank : 73)
Query Neighborhood Hits	443	Target Neighborhood Hits	374	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

MAGC1_HUMAN
NC score	0.027988 (rank : 302)	θ value	3.0926 (rank : 248)
Query Neighborhood Hits	443	Target Neighborhood Hits	431	Shared Neighborhood Hits	62
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SF3B1_MOUSE
NC score	0.027959 (rank : 303)	θ value	1.81305 (rank : 205)
Query Neighborhood Hits	443	Target Neighborhood Hits	352	Shared Neighborhood Hits	31
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

DTX2_HUMAN
NC score	0.027936 (rank : 304)	θ value	0.813845 (rank : 144)
Query Neighborhood Hits	443	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

BAZ1A_HUMAN
NC score	0.027914 (rank : 305)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	443	Target Neighborhood Hits	693	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BPAEA_HUMAN
NC score	0.027751 (rank : 306)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	443	Target Neighborhood Hits	1369	Shared Neighborhood Hits	69
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RAI1_HUMAN
NC score	0.027664 (rank : 307)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	443	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

AP180_MOUSE
NC score	0.027583 (rank : 308)	θ value	5.27518 (rank : 299)
Query Neighborhood Hits	443	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

IF4G1_HUMAN
NC score	0.027218 (rank : 309)	θ value	6.88961 (rank : 360)
Query Neighborhood Hits	443	Target Neighborhood Hits	347	Shared Neighborhood Hits	58
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

TACT_HUMAN
NC score	0.026936 (rank : 310)	θ value	3.0926 (rank : 265)
Query Neighborhood Hits	443	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

PA24F_HUMAN
NC score	0.026485 (rank : 311)	θ value	3.0926 (rank : 253)
Query Neighborhood Hits	443	Target Neighborhood Hits	78	Shared Neighborhood Hits	10
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

GP112_HUMAN
NC score	0.026464 (rank : 312)	θ value	0.813845 (rank : 147)
Query Neighborhood Hits	443	Target Neighborhood Hits	441	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TAF9B_HUMAN
NC score	0.026460 (rank : 313)	θ value	2.36792 (rank : 226)
Query Neighborhood Hits	443	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBM6, Q9Y2S3	Gene names	TAF9B, TAF9L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L) (Neuronal cell death-related protein 7) (DN-7).

BAZ2A_MOUSE
NC score	0.026283 (rank : 314)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	443	Target Neighborhood Hits	744	Shared Neighborhood Hits	84
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PGCA_HUMAN
NC score	0.025626 (rank : 315)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	443	Target Neighborhood Hits	821	Shared Neighborhood Hits	68
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SMCE1_MOUSE
NC score	0.025550 (rank : 316)	θ value	5.27518 (rank : 334)
Query Neighborhood Hits	443	Target Neighborhood Hits	409	Shared Neighborhood Hits	43
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

MYO9B_HUMAN
NC score	0.025512 (rank : 317)	θ value	0.00509761 (rank : 44)
Query Neighborhood Hits	443	Target Neighborhood Hits	641	Shared Neighborhood Hits	73
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ARHG3_MOUSE
NC score	0.025417 (rank : 318)	θ value	0.125558 (rank : 88)
Query Neighborhood Hits	443	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

TTC1_HUMAN
NC score	0.025405 (rank : 319)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	443	Target Neighborhood Hits	417	Shared Neighborhood Hits	40
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

CR025_HUMAN
NC score	0.025362 (rank : 320)	θ value	8.99809 (rank : 394)
Query Neighborhood Hits	443	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	Q96B23, Q5XG78, Q6N058, Q86TB5, Q8TCQ5	Gene names	C18orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25.

RBFAL_MOUSE
NC score	0.025204 (rank : 321)	θ value	3.0926 (rank : 255)
Query Neighborhood Hits	443	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3B9	Gene names
Domain Architecture	No domain graphic available
Description	Putative ribosome-binding factor A, mitochondrial precursor.

NF2L3_HUMAN
NC score	0.024741 (rank : 322)	θ value	0.813845 (rank : 148)
Query Neighborhood Hits	443	Target Neighborhood Hits	150	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

TMM29_HUMAN
NC score	0.024637 (rank : 323)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	443	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDB6, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q9UI49	Gene names	TMEM29
Domain Architecture	No domain graphic available
Description	Transmembrane protein 29.

F126A_MOUSE
NC score	0.024605 (rank : 324)	θ value	3.0926 (rank : 243)
Query Neighborhood Hits	443	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P9N1, Q99NC4	Gene names	Fam126a, Drctnnb1a
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

MMRN2_HUMAN
NC score	0.024586 (rank : 325)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	443	Target Neighborhood Hits	400	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

GAB1_HUMAN
NC score	0.023788 (rank : 326)	θ value	1.81305 (rank : 188)
Query Neighborhood Hits	443	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GRIPE_MOUSE
NC score	0.023759 (rank : 327)	θ value	1.38821 (rank : 175)
Query Neighborhood Hits	443	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

AZI1_HUMAN
NC score	0.023670 (rank : 328)	θ value	0.21417 (rank : 102)
Query Neighborhood Hits	443	Target Neighborhood Hits	1000	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

TCF20_HUMAN
NC score	0.023615 (rank : 329)	θ value	5.27518 (rank : 337)
Query Neighborhood Hits	443	Target Neighborhood Hits	323	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

RIF1_MOUSE
NC score	0.023341 (rank : 330)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	443	Target Neighborhood Hits	315	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

F10A4_HUMAN
NC score	0.023263 (rank : 331)	θ value	6.88961 (rank : 354)
Query Neighborhood Hits	443	Target Neighborhood Hits	249	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

CARD6_HUMAN
NC score	0.023146 (rank : 332)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	443	Target Neighborhood Hits	145	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

IF4G1_MOUSE
NC score	0.022742 (rank : 333)	θ value	8.99809 (rank : 403)
Query Neighborhood Hits	443	Target Neighborhood Hits	534	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PRG3_MOUSE
NC score	0.022682 (rank : 334)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	443	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

SVIL_MOUSE
NC score	0.022664 (rank : 335)	θ value	3.0926 (rank : 264)
Query Neighborhood Hits	443	Target Neighborhood Hits	439	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TULP4_HUMAN
NC score	0.022494 (rank : 336)	θ value	2.36792 (rank : 229)
Query Neighborhood Hits	443	Target Neighborhood Hits	426	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ELF4_MOUSE
NC score	0.022346 (rank : 337)	θ value	1.06291 (rank : 156)
Query Neighborhood Hits	443	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

BPA1_MOUSE
NC score	0.022309 (rank : 338)	θ value	0.813845 (rank : 139)
Query Neighborhood Hits	443	Target Neighborhood Hits	1477	Shared Neighborhood Hits	85
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CR025_MOUSE
NC score	0.022243 (rank : 339)	θ value	8.99809 (rank : 395)
Query Neighborhood Hits	443	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BH50, Q3TQ72, Q8BU43	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25 homolog.

PPAC3_MOUSE
NC score	0.022237 (rank : 340)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	443	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

UBP5_MOUSE
NC score	0.022195 (rank : 341)	θ value	1.81305 (rank : 209)
Query Neighborhood Hits	443	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

FANCJ_HUMAN
NC score	0.021957 (rank : 342)	θ value	1.06291 (rank : 157)
Query Neighborhood Hits	443	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

PGCA_MOUSE
NC score	0.021837 (rank : 343)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	443	Target Neighborhood Hits	643	Shared Neighborhood Hits	63
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

BPAEA_MOUSE
NC score	0.021805 (rank : 344)	θ value	0.813845 (rank : 140)
Query Neighborhood Hits	443	Target Neighborhood Hits	1480	Shared Neighborhood Hits	77
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ZCH11_HUMAN
NC score	0.021612 (rank : 345)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	443	Target Neighborhood Hits	278	Shared Neighborhood Hits	40
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

GOGB1_HUMAN
NC score	0.021434 (rank : 346)	θ value	0.21417 (rank : 104)
Query Neighborhood Hits	443	Target Neighborhood Hits	2297	Shared Neighborhood Hits	125
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NIN_MOUSE
NC score	0.021418 (rank : 347)	θ value	0.163984 (rank : 97)
Query Neighborhood Hits	443	Target Neighborhood Hits	1376	Shared Neighborhood Hits	72
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

EF2K_MOUSE
NC score	0.021232 (rank : 348)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	443	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

UBP5_HUMAN
NC score	0.021149 (rank : 349)	θ value	2.36792 (rank : 230)
Query Neighborhood Hits	443	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

TMF1_HUMAN
NC score	0.021124 (rank : 350)	θ value	1.06291 (rank : 164)
Query Neighborhood Hits	443	Target Neighborhood Hits	987	Shared Neighborhood Hits	67
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

ALMS1_MOUSE
NC score	0.020928 (rank : 351)	θ value	1.38821 (rank : 169)
Query Neighborhood Hits	443	Target Neighborhood Hits	181	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

SAPS1_HUMAN
NC score	0.020887 (rank : 352)	θ value	5.27518 (rank : 331)
Query Neighborhood Hits	443	Target Neighborhood Hits	704	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

E41L3_MOUSE
NC score	0.020737 (rank : 353)	θ value	0.279714 (rank : 108)
Query Neighborhood Hits	443	Target Neighborhood Hits	250	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

GP179_HUMAN
NC score	0.020666 (rank : 354)	θ value	6.88961 (rank : 358)
Query Neighborhood Hits	443	Target Neighborhood Hits	372	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

TPR_HUMAN
NC score	0.020532 (rank : 355)	θ value	1.06291 (rank : 165)
Query Neighborhood Hits	443	Target Neighborhood Hits	1921	Shared Neighborhood Hits	135
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CUTL1_MOUSE
NC score	0.020132 (rank : 356)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	443	Target Neighborhood Hits	1620	Shared Neighborhood Hits	112
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DGKZ_HUMAN
NC score	0.019843 (rank : 357)	θ value	0.125558 (rank : 89)
Query Neighborhood Hits	443	Target Neighborhood Hits	551	Shared Neighborhood Hits	17
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

RAD18_MOUSE
NC score	0.019782 (rank : 358)	θ value	1.81305 (rank : 201)
Query Neighborhood Hits	443	Target Neighborhood Hits	230	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

MCPH1_MOUSE
NC score	0.019723 (rank : 359)	θ value	3.0926 (rank : 250)
Query Neighborhood Hits	443	Target Neighborhood Hits	116	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

RHBD3_HUMAN
NC score	0.019644 (rank : 360)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	443	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3P4, Q6I9X3, Q9UGQ7	Gene names	RHBDD3, C22orf3
Domain Architecture
Description	Rhomboid domain-containing protein 3.

NUPL_MOUSE
NC score	0.019236 (rank : 361)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	443	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

CD34_MOUSE
NC score	0.019207 (rank : 362)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	443	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	Q64314, Q62550, Q62551	Gene names	Cd34
Domain Architecture
Description	Hematopoietic progenitor cell antigen CD34 precursor.

GRIPE_HUMAN
NC score	0.019091 (rank : 363)	θ value	3.0926 (rank : 246)
Query Neighborhood Hits	443	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

EF2K_HUMAN
NC score	0.019086 (rank : 364)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	443	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

ESPL1_HUMAN
NC score	0.019002 (rank : 365)	θ value	1.81305 (rank : 187)
Query Neighborhood Hits	443	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

F126A_HUMAN
NC score	0.018883 (rank : 366)	θ value	6.88961 (rank : 355)
Query Neighborhood Hits	443	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYI3, Q6N010, Q75MR4, Q7LDZ4, Q96MX1, Q96NQ6	Gene names	FAM126A, DRCTNNB1A
Domain Architecture	No domain graphic available
Description	Protein FAM126A (Down-regulated by CTNNB1 protein A).

AKAP4_HUMAN
NC score	0.018823 (rank : 367)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	443	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

GMPR1_HUMAN
NC score	0.018790 (rank : 368)	θ value	1.38821 (rank : 173)
Query Neighborhood Hits	443	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P36959, Q96HQ6	Gene names	GMPR, GMPR1
Domain Architecture
Description	GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1).

SC23B_HUMAN
NC score	0.018603 (rank : 369)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	443	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q15437, Q5W183, Q9BS15, Q9BSI2, Q9H1D7	Gene names	SEC23B
Domain Architecture
Description	Protein transport protein Sec23B (SEC23-related protein B).

SC23B_MOUSE
NC score	0.018536 (rank : 370)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	443	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D662, Q3U6B3, Q99K49, Q9QZ68	Gene names	Sec23b
Domain Architecture
Description	Protein transport protein Sec23B (SEC23-related protein B).

THUM1_MOUSE
NC score	0.018366 (rank : 371)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	443	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	Q99J36, Q3U6Y3	Gene names	Thumpd1
Domain Architecture
Description	THUMP domain-containing protein 1.

CD68_MOUSE
NC score	0.018265 (rank : 372)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	443	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	P31996	Gene names	Cd68
Domain Architecture
Description	Macrosialin precursor (CD68 antigen).

MACF4_HUMAN
NC score	0.018186 (rank : 373)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	443	Target Neighborhood Hits	1321	Shared Neighborhood Hits	84
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SEPT9_HUMAN
NC score	0.017980 (rank : 374)	θ value	3.0926 (rank : 260)
Query Neighborhood Hits	443	Target Neighborhood Hits	706	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CGRE1_HUMAN
NC score	0.017951 (rank : 375)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	443	Target Neighborhood Hits	354	Shared Neighborhood Hits	30
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

ATF4_MOUSE
NC score	0.017865 (rank : 376)	θ value	5.27518 (rank : 300)
Query Neighborhood Hits	443	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

BNC2_HUMAN
NC score	0.017532 (rank : 377)	θ value	4.03905 (rank : 274)
Query Neighborhood Hits	443	Target Neighborhood Hits	439	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

PDZD2_HUMAN
NC score	0.017502 (rank : 378)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	443	Target Neighborhood Hits	772	Shared Neighborhood Hits	78
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

TOIP2_MOUSE
NC score	0.017360 (rank : 379)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	443	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

EP15R_MOUSE
NC score	0.017187 (rank : 380)	θ value	2.36792 (rank : 216)
Query Neighborhood Hits	443	Target Neighborhood Hits	1135	Shared Neighborhood Hits	80
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

DCR1A_HUMAN
NC score	0.017176 (rank : 381)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	443	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

LIPA3_MOUSE
NC score	0.017153 (rank : 382)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	443	Target Neighborhood Hits	636	Shared Neighborhood Hits	49
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MTG8_HUMAN
NC score	0.016968 (rank : 383)	θ value	3.0926 (rank : 252)
Query Neighborhood Hits	443	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

NGEF_HUMAN
NC score	0.016967 (rank : 384)	θ value	0.813845 (rank : 149)
Query Neighborhood Hits	443	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ANK3_HUMAN
NC score	0.016957 (rank : 385)	θ value	5.27518 (rank : 298)
Query Neighborhood Hits	443	Target Neighborhood Hits	853	Shared Neighborhood Hits	93
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

AKAP8_HUMAN
NC score	0.016878 (rank : 386)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	443	Target Neighborhood Hits	166	Shared Neighborhood Hits	26
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

LRBA_HUMAN
NC score	0.016723 (rank : 387)	θ value	3.0926 (rank : 247)
Query Neighborhood Hits	443	Target Neighborhood Hits	196	Shared Neighborhood Hits	24
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

ITF2_MOUSE
NC score	0.016404 (rank : 388)	θ value	6.88961 (rank : 362)
Query Neighborhood Hits	443	Target Neighborhood Hits	154	Shared Neighborhood Hits	20
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

OXRP_HUMAN
NC score	0.016359 (rank : 389)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	443	Target Neighborhood Hits	544	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SAFB2_HUMAN
NC score	0.016276 (rank : 390)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	443	Target Neighborhood Hits	720	Shared Neighborhood Hits	67
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

BRE1A_HUMAN
NC score	0.016214 (rank : 391)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	443	Target Neighborhood Hits	1071	Shared Neighborhood Hits	77
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

SSBP4_HUMAN
NC score	0.016181 (rank : 392)	θ value	0.365318 (rank : 119)
Query Neighborhood Hits	443	Target Neighborhood Hits	753	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

PEG3_MOUSE
NC score	0.016169 (rank : 393)	θ value	0.0330416 (rank : 65)
Query Neighborhood Hits	443	Target Neighborhood Hits	1101	Shared Neighborhood Hits	86
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

STAR8_HUMAN
NC score	0.016138 (rank : 394)	θ value	0.62314 (rank : 136)
Query Neighborhood Hits	443	Target Neighborhood Hits	216	Shared Neighborhood Hits	24
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

SHAN1_HUMAN
NC score	0.016121 (rank : 395)	θ value	6.88961 (rank : 371)
Query Neighborhood Hits	443	Target Neighborhood Hits	1041	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

MACF1_HUMAN
NC score	0.016109 (rank : 396)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	443	Target Neighborhood Hits	1341	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

PSMD2_MOUSE
NC score	0.016071 (rank : 397)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	443	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

MAML1_HUMAN
NC score	0.015955 (rank : 398)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	443	Target Neighborhood Hits	228	Shared Neighborhood Hits	36
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PRG3_HUMAN
NC score	0.015747 (rank : 399)	θ value	6.88961 (rank : 368)
Query Neighborhood Hits	443	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

SETX_HUMAN
NC score	0.015540 (rank : 400)	θ value	4.03905 (rank : 288)
Query Neighborhood Hits	443	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

LIPA3_HUMAN
NC score	0.015526 (rank : 401)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	443	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MTG8_MOUSE
NC score	0.015454 (rank : 402)	θ value	4.03905 (rank : 284)
Query Neighborhood Hits	443	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

MGRN1_HUMAN
NC score	0.015337 (rank : 403)	θ value	4.03905 (rank : 283)
Query Neighborhood Hits	443	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

NU205_HUMAN
NC score	0.015106 (rank : 404)	θ value	6.88961 (rank : 367)
Query Neighborhood Hits	443	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

MAGD2_HUMAN
NC score	0.015041 (rank : 405)	θ value	3.0926 (rank : 249)
Query Neighborhood Hits	443	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UNF1, O76058, Q5BJF3, Q8NAL6, Q9H218, Q9P0U9, Q9UM52	Gene names	MAGED2, BCG1
Domain Architecture
Description	Melanoma-associated antigen D2 (MAGE-D2 antigen) (MAGE-D) (Breast cancer-associated gene 1 protein) (BCG-1) (11B6) (Hepatocellular carcinoma-associated protein JCL-1).

TTC1_MOUSE
NC score	0.015008 (rank : 406)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	443	Target Neighborhood Hits	145	Shared Neighborhood Hits	13
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

DNMBP_HUMAN
NC score	0.014994 (rank : 407)	θ value	2.36792 (rank : 215)
Query Neighborhood Hits	443	Target Neighborhood Hits	413	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PACN2_MOUSE
NC score	0.014822 (rank : 408)	θ value	1.81305 (rank : 198)
Query Neighborhood Hits	443	Target Neighborhood Hits	382	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

MAGB6_HUMAN
NC score	0.014464 (rank : 409)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	443	Target Neighborhood Hits	184	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

BCOR_HUMAN
NC score	0.014360 (rank : 410)	θ value	4.03905 (rank : 272)
Query Neighborhood Hits	443	Target Neighborhood Hits	609	Shared Neighborhood Hits	55
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

UACA_HUMAN
NC score	0.014191 (rank : 411)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	443	Target Neighborhood Hits	1622	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

JIP4_MOUSE
NC score	0.014023 (rank : 412)	θ value	6.88961 (rank : 363)
Query Neighborhood Hits	443	Target Neighborhood Hits	593	Shared Neighborhood Hits	48
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

GIT1_MOUSE
NC score	0.014012 (rank : 413)	θ value	3.0926 (rank : 245)
Query Neighborhood Hits	443	Target Neighborhood Hits	341	Shared Neighborhood Hits	23
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

CCDC7_HUMAN
NC score	0.013877 (rank : 414)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	443	Target Neighborhood Hits	253	Shared Neighborhood Hits	21
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

REST_MOUSE
NC score	0.013853 (rank : 415)	θ value	4.03905 (rank : 286)
Query Neighborhood Hits	443	Target Neighborhood Hits	1506	Shared Neighborhood Hits	85
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

BNC2_MOUSE
NC score	0.013804 (rank : 416)	θ value	8.99809 (rank : 388)
Query Neighborhood Hits	443	Target Neighborhood Hits	456	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

ZHX2_MOUSE
NC score	0.013743 (rank : 417)	θ value	3.0926 (rank : 271)
Query Neighborhood Hits	443	Target Neighborhood Hits	435	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

SPTA2_HUMAN
NC score	0.013716 (rank : 418)	θ value	3.0926 (rank : 261)
Query Neighborhood Hits	443	Target Neighborhood Hits	888	Shared Neighborhood Hits	44
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

XKR5_HUMAN
NC score	0.013683 (rank : 419)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	443	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UX68, Q5GH74	Gene names	XKR5, XRG5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

PLVAP_HUMAN
NC score	0.013384 (rank : 420)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	443	Target Neighborhood Hits	397	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

CEL_HUMAN
NC score	0.013338 (rank : 421)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	443	Target Neighborhood Hits	896	Shared Neighborhood Hits	68
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ITF2_HUMAN
NC score	0.013333 (rank : 422)	θ value	6.88961 (rank : 361)
Query Neighborhood Hits	443	Target Neighborhood Hits	168	Shared Neighborhood Hits	17
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

GOGA4_MOUSE
NC score	0.013140 (rank : 423)	θ value	6.88961 (rank : 357)
Query Neighborhood Hits	443	Target Neighborhood Hits	1939	Shared Neighborhood Hits	106
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CJ118_MOUSE
NC score	0.012888 (rank : 424)	θ value	1.81305 (rank : 185)
Query Neighborhood Hits	443	Target Neighborhood Hits	1132	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

STAT6_HUMAN
NC score	0.012851 (rank : 425)	θ value	0.62314 (rank : 137)
Query Neighborhood Hits	443	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

THA11_HUMAN
NC score	0.012847 (rank : 426)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	443	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK4, O94795	Gene names	THAP11
Domain Architecture
Description	THAP domain-containing protein 11.

TIF1G_MOUSE
NC score	0.012823 (rank : 427)	θ value	4.03905 (rank : 289)
Query Neighborhood Hits	443	Target Neighborhood Hits	498	Shared Neighborhood Hits	47
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

CU025_HUMAN
NC score	0.012817 (rank : 428)	θ value	4.03905 (rank : 277)
Query Neighborhood Hits	443	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y426, Q5R2V7, Q6AHX8, Q9NSE6	Gene names	C21orf25, C21orf258
Domain Architecture	No domain graphic available
Description	Protein C21orf25 precursor.

TE2IP_HUMAN
NC score	0.012715 (rank : 429)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	443	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

NCOA5_HUMAN
NC score	0.012649 (rank : 430)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	443	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

HOME2_MOUSE
NC score	0.012475 (rank : 431)	θ value	8.99809 (rank : 402)
Query Neighborhood Hits	443	Target Neighborhood Hits	882	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

CHD9_HUMAN
NC score	0.012422 (rank : 432)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	443	Target Neighborhood Hits	343	Shared Neighborhood Hits	55
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

TITIN_HUMAN
NC score	0.012384 (rank : 433)	θ value	1.06291 (rank : 163)
Query Neighborhood Hits	443	Target Neighborhood Hits	2923	Shared Neighborhood Hits	163
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AMOL1_MOUSE
NC score	0.012342 (rank : 434)	θ value	8.99809 (rank : 385)
Query Neighborhood Hits	443	Target Neighborhood Hits	445	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

PO6F2_HUMAN
NC score	0.012293 (rank : 435)	θ value	3.0926 (rank : 254)
Query Neighborhood Hits	443	Target Neighborhood Hits	618	Shared Neighborhood Hits	50
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

RB6I2_HUMAN
NC score	0.011888 (rank : 436)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	443	Target Neighborhood Hits	1584	Shared Neighborhood Hits	92
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

UBP10_HUMAN
NC score	0.011797 (rank : 437)	θ value	3.0926 (rank : 268)
Query Neighborhood Hits	443	Target Neighborhood Hits	153	Shared Neighborhood Hits	20
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

TMUB2_MOUSE
NC score	0.011651 (rank : 438)	θ value	4.03905 (rank : 290)
Query Neighborhood Hits	443	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q3V209, Q8K0X0, Q91YQ0, Q9D8C5	Gene names	Tmub2
Domain Architecture	No domain graphic available
Description	Transmembrane and ubiquitin-like domain-containing protein 2.

CCHCR_HUMAN
NC score	0.011650 (rank : 439)	θ value	8.99809 (rank : 389)
Query Neighborhood Hits	443	Target Neighborhood Hits	717	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

HAT1_HUMAN
NC score	0.011630 (rank : 440)	θ value	8.99809 (rank : 401)
Query Neighborhood Hits	443	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	O14929, Q49A44, Q53QF0, Q53SU4	Gene names	HAT1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48).

HDGR3_HUMAN
NC score	0.011594 (rank : 441)	θ value	6.88961 (rank : 359)
Query Neighborhood Hits	443	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

K0323_MOUSE
NC score	0.011410 (rank : 442)	θ value	8.99809 (rank : 407)
Query Neighborhood Hits	443	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U38, Q8BGJ6, Q8C082	Gene names	Kiaa0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

RPGF6_HUMAN
NC score	0.011100 (rank : 443)	θ value	3.0926 (rank : 256)
Query Neighborhood Hits	443	Target Neighborhood Hits	266	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

CMTA1_HUMAN
NC score	0.010989 (rank : 444)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	443	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CDC27_HUMAN
NC score	0.010960 (rank : 445)	θ value	8.99809 (rank : 390)
Query Neighborhood Hits	443	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

LY10_HUMAN
NC score	0.010891 (rank : 446)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	443	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SV2C_HUMAN
NC score	0.010774 (rank : 447)	θ value	3.0926 (rank : 263)
Query Neighborhood Hits	443	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

PTPRJ_MOUSE
NC score	0.010563 (rank : 448)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	443	Target Neighborhood Hits	188	Shared Neighborhood Hits	12
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

DDFL1_HUMAN
NC score	0.010542 (rank : 449)	θ value	8.99809 (rank : 397)
Query Neighborhood Hits	443	Target Neighborhood Hits	353	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FGD6_HUMAN
NC score	0.010516 (rank : 450)	θ value	3.0926 (rank : 244)
Query Neighborhood Hits	443	Target Neighborhood Hits	237	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

AQR_MOUSE
NC score	0.010302 (rank : 451)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	443	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

INVS_MOUSE
NC score	0.010277 (rank : 452)	θ value	8.99809 (rank : 404)
Query Neighborhood Hits	443	Target Neighborhood Hits	609	Shared Neighborhood Hits	52
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

GOG8A_HUMAN
NC score	0.010253 (rank : 453)	θ value	8.99809 (rank : 400)
Query Neighborhood Hits	443	Target Neighborhood Hits	635	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

CNGB3_HUMAN
NC score	0.010243 (rank : 454)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	443	Target Neighborhood Hits	206	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

PTN13_MOUSE
NC score	0.010062 (rank : 455)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	443	Target Neighborhood Hits	426	Shared Neighborhood Hits	27
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

SNX19_HUMAN
NC score	0.009853 (rank : 456)	θ value	6.88961 (rank : 374)
Query Neighborhood Hits	443	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

UBP33_HUMAN
NC score	0.009844 (rank : 457)	θ value	4.03905 (rank : 291)
Query Neighborhood Hits	443	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

ZHX2_HUMAN
NC score	0.009797 (rank : 458)	θ value	3.0926 (rank : 270)
Query Neighborhood Hits	443	Target Neighborhood Hits	347	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6X8	Gene names	ZHX2, AFR1, KIAA0854, RAF
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

PDE1C_MOUSE
NC score	0.009791 (rank : 459)	θ value	1.81305 (rank : 200)
Query Neighborhood Hits	443	Target Neighborhood Hits	161	Shared Neighborhood Hits	27
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

HLX1_MOUSE
NC score	0.009521 (rank : 460)	θ value	1.06291 (rank : 158)
Query Neighborhood Hits	443	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	Q61670	Gene names	Hlx1, Hlx
Domain Architecture
Description	Homeobox protein HLX1.

LPIN1_MOUSE
NC score	0.009452 (rank : 461)	θ value	6.88961 (rank : 364)
Query Neighborhood Hits	443	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZP3, Q9CQI2, Q9JLG6	Gene names	Lpin1, Fld
Domain Architecture
Description	Lipin-1 (Fatty liver dystrophy protein).

CT032_HUMAN
NC score	0.009214 (rank : 462)	θ value	8.99809 (rank : 396)
Query Neighborhood Hits	443	Target Neighborhood Hits	235	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

EPC1_HUMAN
NC score	0.009189 (rank : 463)	θ value	3.0926 (rank : 242)
Query Neighborhood Hits	443	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

PDE4D_MOUSE
NC score	0.009031 (rank : 464)	θ value	4.03905 (rank : 285)
Query Neighborhood Hits	443	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

TOM1_HUMAN
NC score	0.009004 (rank : 465)	θ value	3.0926 (rank : 267)
Query Neighborhood Hits	443	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

SSH2_HUMAN
NC score	0.008979 (rank : 466)	θ value	1.81305 (rank : 207)
Query Neighborhood Hits	443	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

PDE4D_HUMAN
NC score	0.008949 (rank : 467)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	443	Target Neighborhood Hits	122	Shared Neighborhood Hits	24
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

ITPR1_HUMAN
NC score	0.008763 (rank : 468)	θ value	1.38821 (rank : 176)
Query Neighborhood Hits	443	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

BMP3_HUMAN
NC score	0.008631 (rank : 469)	θ value	1.06291 (rank : 154)
Query Neighborhood Hits	443	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	P12645	Gene names	BMP3
Domain Architecture
Description	Bone morphogenetic protein 3 precursor (BMP-3) (Osteogenin) (BMP-3A).

ULE1B_MOUSE
NC score	0.008599 (rank : 470)	θ value	8.99809 (rank : 439)
Query Neighborhood Hits	443	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

FOXC1_HUMAN
NC score	0.008530 (rank : 471)	θ value	1.38821 (rank : 172)
Query Neighborhood Hits	443	Target Neighborhood Hits	208	Shared Neighborhood Hits	30
SwissProt Accessions	Q12948, Q86UP7, Q9BYM1, Q9NUE5, Q9UDD0, Q9UP06	Gene names	FOXC1, FKHL7, FREAC3
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3).

DPPA4_HUMAN
NC score	0.008379 (rank : 472)	θ value	6.88961 (rank : 352)
Query Neighborhood Hits	443	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q7L190, Q9H9N5, Q9NVI6	Gene names	DPPA4
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 4.

K0256_MOUSE
NC score	0.008247 (rank : 473)	θ value	8.99809 (rank : 406)
Query Neighborhood Hits	443	Target Neighborhood Hits	121	Shared Neighborhood Hits	23
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

TEX14_HUMAN
NC score	0.008243 (rank : 474)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	443	Target Neighborhood Hits	1103	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANC1_HUMAN
NC score	0.008230 (rank : 475)	θ value	5.27518 (rank : 296)
Query Neighborhood Hits	443	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

SPDYB_MOUSE
NC score	0.008219 (rank : 476)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	443	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q5IBH6	Gene names	Spdyb
Domain Architecture	No domain graphic available
Description	Speedy protein B (Rapid inducer of G2/M progression in oocytes B) (RINGO B) (mSpy/Ringo B).

DIAP3_MOUSE
NC score	0.008178 (rank : 477)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	443	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DNL4_HUMAN
NC score	0.008065 (rank : 478)	θ value	8.99809 (rank : 398)
Query Neighborhood Hits	443	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

MRE11_MOUSE
NC score	0.007926 (rank : 479)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	443	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

CENG1_MOUSE
NC score	0.007845 (rank : 480)	θ value	8.99809 (rank : 392)
Query Neighborhood Hits	443	Target Neighborhood Hits	531	Shared Neighborhood Hits	36
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

GAK7_HUMAN
NC score	0.007794 (rank : 481)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	443	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

MTMR3_MOUSE
NC score	0.007730 (rank : 482)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	443	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

STAM2_MOUSE
NC score	0.007628 (rank : 483)	θ value	6.88961 (rank : 375)
Query Neighborhood Hits	443	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

MEFV_MOUSE
NC score	0.007335 (rank : 484)	θ value	4.03905 (rank : 282)
Query Neighborhood Hits	443	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

FOXC1_MOUSE
NC score	0.007293 (rank : 485)	θ value	6.88961 (rank : 356)
Query Neighborhood Hits	443	Target Neighborhood Hits	218	Shared Neighborhood Hits	28
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

BUB1_HUMAN
NC score	0.007137 (rank : 486)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	443	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

PTPRG_HUMAN
NC score	0.007030 (rank : 487)	θ value	6.88961 (rank : 369)
Query Neighborhood Hits	443	Target Neighborhood Hits	231	Shared Neighborhood Hits	44
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PREX1_HUMAN
NC score	0.006657 (rank : 488)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	443	Target Neighborhood Hits	177	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

HLX1_HUMAN
NC score	0.006630 (rank : 489)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	443	Target Neighborhood Hits	370	Shared Neighborhood Hits	16
SwissProt Accessions	Q14774, Q15988	Gene names	HLX1
Domain Architecture
Description	Homeobox protein HLX1 (Homeobox protein HB24).

CENG1_HUMAN
NC score	0.006491 (rank : 490)	θ value	8.99809 (rank : 391)
Query Neighborhood Hits	443	Target Neighborhood Hits	544	Shared Neighborhood Hits	33
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

BMP3_MOUSE
NC score	0.006428 (rank : 491)	θ value	4.03905 (rank : 273)
Query Neighborhood Hits	443	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE5	Gene names	Bmp3
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 3 precursor (BMP-3).

FOXR2_HUMAN
NC score	0.006389 (rank : 492)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	443	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PJQ5	Gene names	FOXR2, FOXN6
Domain Architecture	No domain graphic available
Description	Forkhead box protein R2 (Forkhead box protein N6).

LAMA2_MOUSE
NC score	0.006113 (rank : 493)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	443	Target Neighborhood Hits	1198	Shared Neighborhood Hits	56
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PO6F1_MOUSE
NC score	0.005989 (rank : 494)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	443	Target Neighborhood Hits	581	Shared Neighborhood Hits	35
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

FIGN_HUMAN
NC score	0.005975 (rank : 495)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	443	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

K0195_HUMAN
NC score	0.005943 (rank : 496)	θ value	8.99809 (rank : 405)
Query Neighborhood Hits	443	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

ZFY1_MOUSE
NC score	0.005895 (rank : 497)	θ value	0.00665767 (rank : 48)
Query Neighborhood Hits	443	Target Neighborhood Hits	790	Shared Neighborhood Hits	33
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ZN217_HUMAN
NC score	0.005739 (rank : 498)	θ value	2.36792 (rank : 231)
Query Neighborhood Hits	443	Target Neighborhood Hits	905	Shared Neighborhood Hits	46
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

DDX51_HUMAN
NC score	0.005695 (rank : 499)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	443	Target Neighborhood Hits	332	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

PTN4_HUMAN
NC score	0.005604 (rank : 500)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	443	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

CAMKV_HUMAN
NC score	0.005361 (rank : 501)	θ value	0.813845 (rank : 141)
Query Neighborhood Hits	443	Target Neighborhood Hits	1084	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

LYST_MOUSE
NC score	0.005021 (rank : 502)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	443	Target Neighborhood Hits	286	Shared Neighborhood Hits	13
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

IC1_MOUSE
NC score	0.004942 (rank : 503)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	443	Target Neighborhood Hits	164	Shared Neighborhood Hits	19
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

PTPRN_MOUSE
NC score	0.004657 (rank : 504)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	443	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

SRPK1_MOUSE
NC score	0.004246 (rank : 505)	θ value	3.0926 (rank : 262)
Query Neighborhood Hits	443	Target Neighborhood Hits	639	Shared Neighborhood Hits	30
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

S4A7_MOUSE
NC score	0.004169 (rank : 506)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	443	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

STRN3_HUMAN
NC score	0.003986 (rank : 507)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	443	Target Neighborhood Hits	316	Shared Neighborhood Hits	13
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

NEK1_MOUSE
NC score	0.003884 (rank : 508)	θ value	0.365318 (rank : 116)
Query Neighborhood Hits	443	Target Neighborhood Hits	1311	Shared Neighborhood Hits	78
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

TBX10_HUMAN
NC score	0.003538 (rank : 509)	θ value	3.0926 (rank : 266)
Query Neighborhood Hits	443	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

AHI1_HUMAN
NC score	0.003497 (rank : 510)	θ value	8.99809 (rank : 384)
Query Neighborhood Hits	443	Target Neighborhood Hits	537	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

FOXO4_MOUSE
NC score	0.003428 (rank : 511)	θ value	8.99809 (rank : 399)
Query Neighborhood Hits	443	Target Neighborhood Hits	168	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WVH3	Gene names	Mllt7, Afx, Afx1, Fkhr3, Foxo4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Afxh) (Forkhead box protein O4).

SEM6C_HUMAN
NC score	0.003357 (rank : 512)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	443	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

LATS1_HUMAN
NC score	0.003328 (rank : 513)	θ value	4.03905 (rank : 280)
Query Neighborhood Hits	443	Target Neighborhood Hits	1057	Shared Neighborhood Hits	56
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

GP124_MOUSE
NC score	0.003283 (rank : 514)	θ value	2.36792 (rank : 217)
Query Neighborhood Hits	443	Target Neighborhood Hits	423	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

LATS2_HUMAN
NC score	0.003133 (rank : 515)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	443	Target Neighborhood Hits	884	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

NFASC_HUMAN
NC score	0.003036 (rank : 516)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	443	Target Neighborhood Hits	497	Shared Neighborhood Hits	25
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

LATS1_MOUSE
NC score	0.003000 (rank : 517)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	443	Target Neighborhood Hits	1027	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

NFASC_MOUSE
NC score	0.003000 (rank : 518)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	443	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

VLDLR_HUMAN
NC score	0.002975 (rank : 519)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	443	Target Neighborhood Hits	383	Shared Neighborhood Hits	7
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

SIP1_HUMAN
NC score	0.002888 (rank : 520)	θ value	6.88961 (rank : 372)
Query Neighborhood Hits	443	Target Neighborhood Hits	832	Shared Neighborhood Hits	51
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

ERR1_HUMAN
NC score	0.002707 (rank : 521)	θ value	6.88961 (rank : 353)
Query Neighborhood Hits	443	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

SUHW1_HUMAN
NC score	0.002521 (rank : 522)	θ value	1.81305 (rank : 208)
Query Neighborhood Hits	443	Target Neighborhood Hits	648	Shared Neighborhood Hits	20
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

LATS2_MOUSE
NC score	0.002514 (rank : 523)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	443	Target Neighborhood Hits	879	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

SIP1_MOUSE
NC score	0.002312 (rank : 524)	θ value	6.88961 (rank : 373)
Query Neighborhood Hits	443	Target Neighborhood Hits	870	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

ZKSC1_HUMAN
NC score	0.002243 (rank : 525)	θ value	0.0961366 (rank : 85)
Query Neighborhood Hits	443	Target Neighborhood Hits	949	Shared Neighborhood Hits	52
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

ZN516_MOUSE
NC score	0.002116 (rank : 526)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	443	Target Neighborhood Hits	1197	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

MGR8_HUMAN
NC score	0.002059 (rank : 527)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	443	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

SCN7A_HUMAN
NC score	0.002016 (rank : 528)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	443	Target Neighborhood Hits	135	Shared Neighborhood Hits	12
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

ANGL2_MOUSE
NC score	0.002010 (rank : 529)	θ value	5.27518 (rank : 297)
Query Neighborhood Hits	443	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

DDX52_HUMAN
NC score	0.001991 (rank : 530)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	443	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

LPXN_HUMAN
NC score	0.001660 (rank : 531)	θ value	4.03905 (rank : 281)
Query Neighborhood Hits	443	Target Neighborhood Hits	159	Shared Neighborhood Hits	5
SwissProt Accessions	O60711	Gene names	LPXN, LDLP
Domain Architecture
Description	Leupaxin.

LDLR_MOUSE
NC score	0.001618 (rank : 532)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	443	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

STK10_HUMAN
NC score	0.001358 (rank : 533)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	443	Target Neighborhood Hits	1921	Shared Neighborhood Hits	102
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

Z297B_MOUSE
NC score	0.001351 (rank : 534)	θ value	1.81305 (rank : 210)
Query Neighborhood Hits	443	Target Neighborhood Hits	806	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DAI4	Gene names	Znf297b, Kiaa0414, Zfp297b
Domain Architecture
Description	Zinc finger protein 297B.

PEG3_HUMAN
NC score	0.000990 (rank : 535)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	443	Target Neighborhood Hits	800	Shared Neighborhood Hits	39
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

TMPS9_HUMAN
NC score	0.000956 (rank : 536)	θ value	2.36792 (rank : 228)
Query Neighborhood Hits	443	Target Neighborhood Hits	276	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

MAST1_MOUSE
NC score	0.000833 (rank : 537)	θ value	0.365318 (rank : 114)
Query Neighborhood Hits	443	Target Neighborhood Hits	1123	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ABCA7_HUMAN
NC score	0.000690 (rank : 538)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	443	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ZN644_HUMAN
NC score	0.000684 (rank : 539)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	443	Target Neighborhood Hits	704	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H582, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9	Gene names	ZNF644, KIAA1221, ZEP2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2).

ZN509_MOUSE
NC score	0.000361 (rank : 540)	θ value	0.47712 (rank : 125)
Query Neighborhood Hits	443	Target Neighborhood Hits	990	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN628_MOUSE
NC score	0.000171 (rank : 541)	θ value	0.125558 (rank : 92)
Query Neighborhood Hits	443	Target Neighborhood Hits	815	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

LRC33_MOUSE
NC score	-0.000046 (rank : 542)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	443	Target Neighborhood Hits	296	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

ZBT10_HUMAN
NC score	-0.000081 (rank : 543)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	443	Target Neighborhood Hits	831	Shared Neighborhood Hits	21
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

MK07_HUMAN
NC score	-0.000275 (rank : 544)	θ value	3.0926 (rank : 251)
Query Neighborhood Hits	443	Target Neighborhood Hits	1087	Shared Neighborhood Hits	58
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

ZF276_HUMAN
NC score	-0.000352 (rank : 545)	θ value	3.0926 (rank : 269)
Query Neighborhood Hits	443	Target Neighborhood Hits	768	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N554	Gene names	ZFP276
Domain Architecture	No domain graphic available
Description	Zinc finger protein 276 homolog (Zfp-276).

HXA5_MOUSE
NC score	-0.000882 (rank : 546)	θ value	4.03905 (rank : 279)
Query Neighborhood Hits	443	Target Neighborhood Hits	338	Shared Neighborhood Hits	8
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

ZN711_HUMAN
NC score	-0.000967 (rank : 547)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	443	Target Neighborhood Hits	751	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

ZXDA_HUMAN
NC score	-0.001218 (rank : 548)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	443	Target Neighborhood Hits	750	Shared Neighborhood Hits	25
SwissProt Accessions	P98168, Q9UJP7	Gene names	ZXDA
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDA.

MARK2_MOUSE
NC score	-0.001265 (rank : 549)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	443	Target Neighborhood Hits	1018	Shared Neighborhood Hits	52
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

SP7_HUMAN
NC score	-0.001490 (rank : 550)	θ value	5.27518 (rank : 335)
Query Neighborhood Hits	443	Target Neighborhood Hits	734	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

ULK1_MOUSE
NC score	-0.002363 (rank : 551)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	443	Target Neighborhood Hits	1214	Shared Neighborhood Hits	50
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

HUNK_HUMAN
NC score	-0.002698 (rank : 552)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	443	Target Neighborhood Hits	884	Shared Neighborhood Hits	23
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

MARK4_MOUSE
NC score	-0.002843 (rank : 553)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	443	Target Neighborhood Hits	898	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

LTK_HUMAN
NC score	-0.004555 (rank : 554)	θ value	6.88961 (rank : 365)
Query Neighborhood Hits	443	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).