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Network neighborhood for query Sequence : MAGI2_MOUSE

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MAGI2_MOUSE
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MAGI1_HUMAN
θ value	0 (rank : 1)	NC score	0.958995 (rank : 3)
Query Neighborhood Hits	370	Target Neighborhood Hits	388	Shared Neighborhood Hits	240
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	0 (rank : 2)	NC score	0.956035 (rank : 4)
Query Neighborhood Hits	370	Target Neighborhood Hits	403	Shared Neighborhood Hits	241
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
θ value	0 (rank : 3)	NC score	0.987701 (rank : 2)
Query Neighborhood Hits	370	Target Neighborhood Hits	373	Shared Neighborhood Hits	288
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	370	Target Neighborhood Hits	370	Shared Neighborhood Hits	370
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MPDZ_HUMAN
θ value	8.36355e-22 (rank : 5)	NC score	0.703165 (rank : 5)
Query Neighborhood Hits	370	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PTN13_HUMAN
θ value	3.51386e-20 (rank : 6)	NC score	0.412979 (rank : 90)
Query Neighborhood Hits	370	Target Neighborhood Hits	471	Shared Neighborhood Hits	195
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

MPDZ_MOUSE
θ value	2.27762e-19 (rank : 7)	NC score	0.696125 (rank : 6)
Query Neighborhood Hits	370	Target Neighborhood Hits	298	Shared Neighborhood Hits	196
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

INADL_MOUSE
θ value	4.29542e-18 (rank : 8)	NC score	0.696021 (rank : 7)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	197
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

PTN13_MOUSE
θ value	6.20254e-17 (rank : 9)	NC score	0.402662 (rank : 101)
Query Neighborhood Hits	370	Target Neighborhood Hits	426	Shared Neighborhood Hits	197
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

INADL_HUMAN
θ value	1.058e-16 (rank : 10)	NC score	0.691367 (rank : 9)
Query Neighborhood Hits	370	Target Neighborhood Hits	260	Shared Neighborhood Hits	193
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

WWC1_HUMAN
θ value	1.058e-16 (rank : 11)	NC score	0.407235 (rank : 96)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	1.058e-16 (rank : 12)	NC score	0.405022 (rank : 98)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

PARD3_HUMAN
θ value	7.58209e-15 (rank : 13)	NC score	0.641785 (rank : 18)
Query Neighborhood Hits	370	Target Neighborhood Hits	312	Shared Neighborhood Hits	166
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

DLG2_HUMAN
θ value	1.68911e-14 (rank : 14)	NC score	0.608752 (rank : 34)
Query Neighborhood Hits	370	Target Neighborhood Hits	279	Shared Neighborhood Hits	182
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
θ value	1.68911e-14 (rank : 15)	NC score	0.614661 (rank : 30)
Query Neighborhood Hits	370	Target Neighborhood Hits	269	Shared Neighborhood Hits	182
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	2.20605e-14 (rank : 16)	NC score	0.616207 (rank : 29)
Query Neighborhood Hits	370	Target Neighborhood Hits	274	Shared Neighborhood Hits	182
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

PARD3_MOUSE
θ value	2.88119e-14 (rank : 17)	NC score	0.643239 (rank : 17)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	164
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

SAV1_MOUSE
θ value	1.09485e-13 (rank : 18)	NC score	0.469224 (rank : 77)
Query Neighborhood Hits	370	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

DLG1_MOUSE
θ value	1.42992e-13 (rank : 19)	NC score	0.605369 (rank : 38)
Query Neighborhood Hits	370	Target Neighborhood Hits	285	Shared Neighborhood Hits	180
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

SAV1_HUMAN
θ value	2.43908e-13 (rank : 20)	NC score	0.469066 (rank : 78)
Query Neighborhood Hits	370	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

WWP2_MOUSE
θ value	3.18553e-13 (rank : 21)	NC score	0.329031 (rank : 135)
Query Neighborhood Hits	370	Target Neighborhood Hits	118	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

DLG1_HUMAN
θ value	4.16044e-13 (rank : 22)	NC score	0.606659 (rank : 36)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	180
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

PZRN4_HUMAN
θ value	5.43371e-13 (rank : 23)	NC score	0.511227 (rank : 69)
Query Neighborhood Hits	370	Target Neighborhood Hits	438	Shared Neighborhood Hits	156
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

WWP2_HUMAN
θ value	9.26847e-13 (rank : 24)	NC score	0.329602 (rank : 133)
Query Neighborhood Hits	370	Target Neighborhood Hits	177	Shared Neighborhood Hits	56
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP1_MOUSE
θ value	2.0648e-12 (rank : 25)	NC score	0.325348 (rank : 141)
Query Neighborhood Hits	370	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

ZO3_HUMAN
θ value	2.69671e-12 (rank : 26)	NC score	0.562197 (rank : 53)
Query Neighborhood Hits	370	Target Neighborhood Hits	219	Shared Neighborhood Hits	174
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

DLG2_MOUSE
θ value	7.84624e-12 (rank : 27)	NC score	0.605770 (rank : 37)
Query Neighborhood Hits	370	Target Neighborhood Hits	271	Shared Neighborhood Hits	181
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG4_HUMAN
θ value	7.84624e-12 (rank : 28)	NC score	0.620541 (rank : 28)
Query Neighborhood Hits	370	Target Neighborhood Hits	286	Shared Neighborhood Hits	185
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	7.84624e-12 (rank : 29)	NC score	0.621489 (rank : 27)
Query Neighborhood Hits	370	Target Neighborhood Hits	282	Shared Neighborhood Hits	187
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

NED4L_HUMAN
θ value	7.84624e-12 (rank : 30)	NC score	0.294698 (rank : 169)
Query Neighborhood Hits	370	Target Neighborhood Hits	238	Shared Neighborhood Hits	56
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	7.84624e-12 (rank : 31)	NC score	0.294984 (rank : 168)
Query Neighborhood Hits	370	Target Neighborhood Hits	231	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

LNX2_HUMAN
θ value	1.02475e-11 (rank : 32)	NC score	0.594357 (rank : 43)
Query Neighborhood Hits	370	Target Neighborhood Hits	389	Shared Neighborhood Hits	180
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

WWP1_HUMAN
θ value	1.02475e-11 (rank : 33)	NC score	0.321779 (rank : 145)
Query Neighborhood Hits	370	Target Neighborhood Hits	262	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

K1849_MOUSE
θ value	1.33837e-11 (rank : 34)	NC score	0.501533 (rank : 72)
Query Neighborhood Hits	370	Target Neighborhood Hits	335	Shared Neighborhood Hits	157
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZO3_MOUSE
θ value	1.74796e-11 (rank : 35)	NC score	0.568302 (rank : 52)
Query Neighborhood Hits	370	Target Neighborhood Hits	224	Shared Neighborhood Hits	179
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PDZD2_HUMAN
θ value	2.98157e-11 (rank : 36)	NC score	0.610405 (rank : 31)
Query Neighborhood Hits	370	Target Neighborhood Hits	772	Shared Neighborhood Hits	221
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

ITCH_MOUSE
θ value	5.08577e-11 (rank : 37)	NC score	0.321712 (rank : 146)
Query Neighborhood Hits	370	Target Neighborhood Hits	127	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

GRIP2_HUMAN
θ value	6.64225e-11 (rank : 38)	NC score	0.637427 (rank : 19)
Query Neighborhood Hits	370	Target Neighborhood Hits	256	Shared Neighborhood Hits	193
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

LIN7B_MOUSE
θ value	6.64225e-11 (rank : 39)	NC score	0.689759 (rank : 11)
Query Neighborhood Hits	370	Target Neighborhood Hits	200	Shared Neighborhood Hits	188
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

NEDD4_HUMAN
θ value	6.64225e-11 (rank : 40)	NC score	0.300823 (rank : 163)
Query Neighborhood Hits	370	Target Neighborhood Hits	214	Shared Neighborhood Hits	50
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

ITCH_HUMAN
θ value	8.67504e-11 (rank : 41)	NC score	0.319846 (rank : 150)
Query Neighborhood Hits	370	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

K1849_HUMAN
θ value	8.67504e-11 (rank : 42)	NC score	0.520518 (rank : 66)
Query Neighborhood Hits	370	Target Neighborhood Hits	220	Shared Neighborhood Hits	147
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

WWOX_HUMAN
θ value	8.67504e-11 (rank : 43)	NC score	0.297843 (rank : 165)
Query Neighborhood Hits	370	Target Neighborhood Hits	115	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	8.67504e-11 (rank : 44)	NC score	0.295190 (rank : 167)
Query Neighborhood Hits	370	Target Neighborhood Hits	118	Shared Neighborhood Hits	43
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

YAP1_MOUSE
θ value	8.67504e-11 (rank : 45)	NC score	0.425078 (rank : 83)
Query Neighborhood Hits	370	Target Neighborhood Hits	96	Shared Neighborhood Hits	56
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PAR3L_HUMAN
θ value	1.133e-10 (rank : 46)	NC score	0.631560 (rank : 22)
Query Neighborhood Hits	370	Target Neighborhood Hits	297	Shared Neighborhood Hits	166
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

LIN7C_HUMAN
θ value	1.47974e-10 (rank : 47)	NC score	0.689268 (rank : 12)
Query Neighborhood Hits	370	Target Neighborhood Hits	198	Shared Neighborhood Hits	188
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	1.47974e-10 (rank : 48)	NC score	0.689268 (rank : 13)
Query Neighborhood Hits	370	Target Neighborhood Hits	198	Shared Neighborhood Hits	188
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7B_HUMAN
θ value	2.52405e-10 (rank : 49)	NC score	0.690439 (rank : 10)
Query Neighborhood Hits	370	Target Neighborhood Hits	200	Shared Neighborhood Hits	188
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LNX1_HUMAN
θ value	2.52405e-10 (rank : 50)	NC score	0.587627 (rank : 47)
Query Neighborhood Hits	370	Target Neighborhood Hits	379	Shared Neighborhood Hits	174
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_MOUSE
θ value	2.52405e-10 (rank : 51)	NC score	0.594529 (rank : 42)
Query Neighborhood Hits	370	Target Neighborhood Hits	407	Shared Neighborhood Hits	183
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PDZD1_HUMAN
θ value	4.30538e-10 (rank : 52)	NC score	0.610287 (rank : 32)
Query Neighborhood Hits	370	Target Neighborhood Hits	190	Shared Neighborhood Hits	154
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LIN7A_HUMAN
θ value	9.59137e-10 (rank : 53)	NC score	0.683680 (rank : 15)
Query Neighborhood Hits	370	Target Neighborhood Hits	193	Shared Neighborhood Hits	187
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	9.59137e-10 (rank : 54)	NC score	0.683789 (rank : 14)
Query Neighborhood Hits	370	Target Neighborhood Hits	193	Shared Neighborhood Hits	187
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

NHRF2_HUMAN
θ value	1.25267e-09 (rank : 55)	NC score	0.608263 (rank : 35)
Query Neighborhood Hits	370	Target Neighborhood Hits	197	Shared Neighborhood Hits	166
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
θ value	1.25267e-09 (rank : 56)	NC score	0.599478 (rank : 41)
Query Neighborhood Hits	370	Target Neighborhood Hits	194	Shared Neighborhood Hits	167
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

NEDD4_MOUSE
θ value	2.13673e-09 (rank : 57)	NC score	0.293545 (rank : 170)
Query Neighborhood Hits	370	Target Neighborhood Hits	212	Shared Neighborhood Hits	52
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

SMUF2_HUMAN
θ value	2.13673e-09 (rank : 58)	NC score	0.305239 (rank : 159)
Query Neighborhood Hits	370	Target Neighborhood Hits	142	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

LAP4_HUMAN
θ value	2.79066e-09 (rank : 59)	NC score	0.427712 (rank : 82)
Query Neighborhood Hits	370	Target Neighborhood Hits	608	Shared Neighborhood Hits	202
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

SMUF1_MOUSE
θ value	3.64472e-09 (rank : 60)	NC score	0.303430 (rank : 162)
Query Neighborhood Hits	370	Target Neighborhood Hits	142	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

LNX1_MOUSE
θ value	6.21693e-09 (rank : 61)	NC score	0.585948 (rank : 48)
Query Neighborhood Hits	370	Target Neighborhood Hits	377	Shared Neighborhood Hits	181
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PDZD7_HUMAN
θ value	8.11959e-09 (rank : 62)	NC score	0.671819 (rank : 16)
Query Neighborhood Hits	370	Target Neighborhood Hits	181	Shared Neighborhood Hits	170
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

WHRN_HUMAN
θ value	8.11959e-09 (rank : 63)	NC score	0.630325 (rank : 23)
Query Neighborhood Hits	370	Target Neighborhood Hits	325	Shared Neighborhood Hits	197
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

ZO1_HUMAN
θ value	1.06045e-08 (rank : 64)	NC score	0.507013 (rank : 71)
Query Neighborhood Hits	370	Target Neighborhood Hits	474	Shared Neighborhood Hits	197
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LAP4_MOUSE
θ value	1.38499e-08 (rank : 65)	NC score	0.420644 (rank : 87)
Query Neighborhood Hits	370	Target Neighborhood Hits	590	Shared Neighborhood Hits	201
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

GRIP1_MOUSE
θ value	2.36244e-08 (rank : 66)	NC score	0.624192 (rank : 25)
Query Neighborhood Hits	370	Target Neighborhood Hits	241	Shared Neighborhood Hits	193
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SYJ2B_HUMAN
θ value	2.36244e-08 (rank : 67)	NC score	0.694528 (rank : 8)
Query Neighborhood Hits	370	Target Neighborhood Hits	162	Shared Neighborhood Hits	159
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

WHRN_MOUSE
θ value	2.36244e-08 (rank : 68)	NC score	0.632717 (rank : 21)
Query Neighborhood Hits	370	Target Neighborhood Hits	412	Shared Neighborhood Hits	209
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

CNKR2_HUMAN
θ value	3.08544e-08 (rank : 69)	NC score	0.250639 (rank : 188)
Query Neighborhood Hits	370	Target Neighborhood Hits	197	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	3.08544e-08 (rank : 70)	NC score	0.250805 (rank : 187)
Query Neighborhood Hits	370	Target Neighborhood Hits	197	Shared Neighborhood Hits	58
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

ZO1_MOUSE
θ value	4.0297e-08 (rank : 71)	NC score	0.510324 (rank : 70)
Query Neighborhood Hits	370	Target Neighborhood Hits	453	Shared Neighborhood Hits	189
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SMUF1_HUMAN
θ value	6.87365e-08 (rank : 72)	NC score	0.292258 (rank : 171)
Query Neighborhood Hits	370	Target Neighborhood Hits	135	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

APBA3_MOUSE
θ value	1.17247e-07 (rank : 73)	NC score	0.423130 (rank : 85)
Query Neighborhood Hits	370	Target Neighborhood Hits	174	Shared Neighborhood Hits	134
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

GRIP1_HUMAN
θ value	1.17247e-07 (rank : 74)	NC score	0.629057 (rank : 24)
Query Neighborhood Hits	370	Target Neighborhood Hits	231	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SNTB2_HUMAN
θ value	1.17247e-07 (rank : 75)	NC score	0.553240 (rank : 59)
Query Neighborhood Hits	370	Target Neighborhood Hits	180	Shared Neighborhood Hits	164
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

PDLI2_HUMAN
θ value	1.53129e-07 (rank : 76)	NC score	0.464523 (rank : 79)
Query Neighborhood Hits	370	Target Neighborhood Hits	245	Shared Neighborhood Hits	131
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

SNTB2_MOUSE
θ value	1.53129e-07 (rank : 77)	NC score	0.552566 (rank : 60)
Query Neighborhood Hits	370	Target Neighborhood Hits	181	Shared Neighborhood Hits	163
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

PDZD1_MOUSE
θ value	1.99992e-07 (rank : 78)	NC score	0.623261 (rank : 26)
Query Neighborhood Hits	370	Target Neighborhood Hits	191	Shared Neighborhood Hits	157
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SNTG2_MOUSE
θ value	1.99992e-07 (rank : 79)	NC score	0.549585 (rank : 62)
Query Neighborhood Hits	370	Target Neighborhood Hits	176	Shared Neighborhood Hits	171
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTA1_HUMAN
θ value	2.61198e-07 (rank : 80)	NC score	0.549039 (rank : 63)
Query Neighborhood Hits	370	Target Neighborhood Hits	186	Shared Neighborhood Hits	171
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

PZRN3_MOUSE
θ value	3.41135e-07 (rank : 81)	NC score	0.483189 (rank : 75)
Query Neighborhood Hits	370	Target Neighborhood Hits	447	Shared Neighborhood Hits	157
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SNTA1_MOUSE
θ value	4.45536e-07 (rank : 82)	NC score	0.540469 (rank : 64)
Query Neighborhood Hits	370	Target Neighborhood Hits	170	Shared Neighborhood Hits	164
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTG2_HUMAN
θ value	7.59969e-07 (rank : 83)	NC score	0.580559 (rank : 51)
Query Neighborhood Hits	370	Target Neighborhood Hits	191	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

USH1C_HUMAN
θ value	7.59969e-07 (rank : 84)	NC score	0.636021 (rank : 20)
Query Neighborhood Hits	370	Target Neighborhood Hits	327	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

PKHA5_HUMAN
θ value	9.92553e-07 (rank : 85)	NC score	0.242901 (rank : 190)
Query Neighborhood Hits	370	Target Neighborhood Hits	455	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

SNTG1_HUMAN
θ value	9.92553e-07 (rank : 86)	NC score	0.556429 (rank : 55)
Query Neighborhood Hits	370	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

NEB2_HUMAN
θ value	1.29631e-06 (rank : 87)	NC score	0.367711 (rank : 113)
Query Neighborhood Hits	370	Target Neighborhood Hits	883	Shared Neighborhood Hits	143
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	1.29631e-06 (rank : 88)	NC score	0.364592 (rank : 115)
Query Neighborhood Hits	370	Target Neighborhood Hits	889	Shared Neighborhood Hits	145
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDZD3_HUMAN
θ value	1.29631e-06 (rank : 89)	NC score	0.558275 (rank : 54)
Query Neighborhood Hits	370	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PZRN3_HUMAN
θ value	1.29631e-06 (rank : 90)	NC score	0.480978 (rank : 76)
Query Neighborhood Hits	370	Target Neighborhood Hits	461	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SNTG1_MOUSE
θ value	1.29631e-06 (rank : 91)	NC score	0.555136 (rank : 58)
Query Neighborhood Hits	370	Target Neighborhood Hits	179	Shared Neighborhood Hits	173
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SYNP2_HUMAN
θ value	1.29631e-06 (rank : 92)	NC score	0.336808 (rank : 125)
Query Neighborhood Hits	370	Target Neighborhood Hits	323	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

ARHGB_HUMAN
θ value	1.69304e-06 (rank : 93)	NC score	0.327364 (rank : 138)
Query Neighborhood Hits	370	Target Neighborhood Hits	375	Shared Neighborhood Hits	160
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

NEB1_HUMAN
θ value	1.69304e-06 (rank : 94)	NC score	0.391825 (rank : 107)
Query Neighborhood Hits	370	Target Neighborhood Hits	829	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NHERF_HUMAN
θ value	2.21117e-06 (rank : 95)	NC score	0.583513 (rank : 49)
Query Neighborhood Hits	370	Target Neighborhood Hits	190	Shared Neighborhood Hits	158
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

APBA3_HUMAN
θ value	2.88788e-06 (rank : 96)	NC score	0.428503 (rank : 81)
Query Neighborhood Hits	370	Target Neighborhood Hits	201	Shared Neighborhood Hits	141
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PDLI2_MOUSE
θ value	3.77169e-06 (rank : 97)	NC score	0.442610 (rank : 80)
Query Neighborhood Hits	370	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PTN4_HUMAN
θ value	3.77169e-06 (rank : 98)	NC score	0.169928 (rank : 209)
Query Neighborhood Hits	370	Target Neighborhood Hits	303	Shared Neighborhood Hits	126
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

SNTB1_HUMAN
θ value	3.77169e-06 (rank : 99)	NC score	0.515069 (rank : 67)
Query Neighborhood Hits	370	Target Neighborhood Hits	157	Shared Neighborhood Hits	152
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

NHERF_MOUSE
θ value	4.92598e-06 (rank : 100)	NC score	0.600074 (rank : 40)
Query Neighborhood Hits	370	Target Neighborhood Hits	195	Shared Neighborhood Hits	162
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

SYNP2_MOUSE
θ value	4.92598e-06 (rank : 101)	NC score	0.373625 (rank : 111)
Query Neighborhood Hits	370	Target Neighborhood Hits	252	Shared Neighborhood Hits	129
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

IL16_HUMAN
θ value	6.43352e-06 (rank : 102)	NC score	0.588560 (rank : 46)
Query Neighborhood Hits	370	Target Neighborhood Hits	207	Shared Neighborhood Hits	148
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZ11_HUMAN
θ value	6.43352e-06 (rank : 103)	NC score	0.609135 (rank : 33)
Query Neighborhood Hits	370	Target Neighborhood Hits	160	Shared Neighborhood Hits	146
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

CSKP_HUMAN
θ value	8.40245e-06 (rank : 104)	NC score	0.133677 (rank : 223)
Query Neighborhood Hits	370	Target Neighborhood Hits	1022	Shared Neighborhood Hits	133
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	8.40245e-06 (rank : 105)	NC score	0.130658 (rank : 224)
Query Neighborhood Hits	370	Target Neighborhood Hits	1027	Shared Neighborhood Hits	133
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

MAST3_HUMAN
θ value	8.40245e-06 (rank : 106)	NC score	0.079482 (rank : 246)
Query Neighborhood Hits	370	Target Neighborhood Hits	1128	Shared Neighborhood Hits	146
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

GOPC_HUMAN
θ value	1.09739e-05 (rank : 107)	NC score	0.582152 (rank : 50)
Query Neighborhood Hits	370	Target Neighborhood Hits	377	Shared Neighborhood Hits	175
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	1.09739e-05 (rank : 108)	NC score	0.591253 (rank : 45)
Query Neighborhood Hits	370	Target Neighborhood Hits	323	Shared Neighborhood Hits	174
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LDB3_MOUSE
θ value	1.09739e-05 (rank : 109)	NC score	0.266435 (rank : 182)
Query Neighborhood Hits	370	Target Neighborhood Hits	510	Shared Neighborhood Hits	126
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

SNTB1_MOUSE
θ value	1.09739e-05 (rank : 110)	NC score	0.511511 (rank : 68)
Query Neighborhood Hits	370	Target Neighborhood Hits	160	Shared Neighborhood Hits	150
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

USH1C_MOUSE
θ value	1.09739e-05 (rank : 111)	NC score	0.591744 (rank : 44)
Query Neighborhood Hits	370	Target Neighborhood Hits	557	Shared Neighborhood Hits	209
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

YAP1_HUMAN
θ value	1.09739e-05 (rank : 112)	NC score	0.328476 (rank : 136)
Query Neighborhood Hits	370	Target Neighborhood Hits	173	Shared Neighborhood Hits	66
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

STXB4_HUMAN
θ value	1.43324e-05 (rank : 113)	NC score	0.423484 (rank : 84)
Query Neighborhood Hits	370	Target Neighborhood Hits	616	Shared Neighborhood Hits	141
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYP2L_HUMAN
θ value	1.43324e-05 (rank : 114)	NC score	0.403236 (rank : 100)
Query Neighborhood Hits	370	Target Neighborhood Hits	400	Shared Neighborhood Hits	143
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PDLI5_MOUSE
θ value	1.87187e-05 (rank : 115)	NC score	0.263603 (rank : 183)
Query Neighborhood Hits	370	Target Neighborhood Hits	287	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SYP2L_MOUSE
θ value	1.87187e-05 (rank : 116)	NC score	0.338864 (rank : 124)
Query Neighborhood Hits	370	Target Neighborhood Hits	289	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

APBA1_HUMAN
θ value	2.44474e-05 (rank : 117)	NC score	0.421086 (rank : 86)
Query Neighborhood Hits	370	Target Neighborhood Hits	325	Shared Neighborhood Hits	154
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PDZ11_MOUSE
θ value	3.19293e-05 (rank : 118)	NC score	0.604555 (rank : 39)
Query Neighborhood Hits	370	Target Neighborhood Hits	154	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SHAN1_HUMAN
θ value	3.19293e-05 (rank : 119)	NC score	0.211251 (rank : 197)
Query Neighborhood Hits	370	Target Neighborhood Hits	1041	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PICK1_MOUSE
θ value	4.1701e-05 (rank : 120)	NC score	0.410919 (rank : 91)
Query Neighborhood Hits	370	Target Neighborhood Hits	131	Shared Neighborhood Hits	122
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

ARHGC_HUMAN
θ value	5.44631e-05 (rank : 121)	NC score	0.300786 (rank : 164)
Query Neighborhood Hits	370	Target Neighborhood Hits	351	Shared Neighborhood Hits	145
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BAG3_MOUSE
θ value	5.44631e-05 (rank : 122)	NC score	0.251460 (rank : 186)
Query Neighborhood Hits	370	Target Neighborhood Hits	513	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PICK1_HUMAN
θ value	5.44631e-05 (rank : 123)	NC score	0.409510 (rank : 94)
Query Neighborhood Hits	370	Target Neighborhood Hits	132	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

STXB4_MOUSE
θ value	5.44631e-05 (rank : 124)	NC score	0.418260 (rank : 88)
Query Neighborhood Hits	370	Target Neighborhood Hits	629	Shared Neighborhood Hits	139
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

WWTR1_HUMAN
θ value	5.44631e-05 (rank : 125)	NC score	0.312472 (rank : 157)
Query Neighborhood Hits	370	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

BAG3_HUMAN
θ value	7.1131e-05 (rank : 126)	NC score	0.273498 (rank : 176)
Query Neighborhood Hits	370	Target Neighborhood Hits	314	Shared Neighborhood Hits	70
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

LDB3_HUMAN
θ value	7.1131e-05 (rank : 127)	NC score	0.262874 (rank : 184)
Query Neighborhood Hits	370	Target Neighborhood Hits	497	Shared Neighborhood Hits	127
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PDLI5_HUMAN
θ value	7.1131e-05 (rank : 128)	NC score	0.262065 (rank : 185)
Query Neighborhood Hits	370	Target Neighborhood Hits	322	Shared Neighborhood Hits	123
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

ARHGC_MOUSE
θ value	9.29e-05 (rank : 129)	NC score	0.296872 (rank : 166)
Query Neighborhood Hits	370	Target Neighborhood Hits	344	Shared Neighborhood Hits	149
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

MPP3_MOUSE
θ value	9.29e-05 (rank : 130)	NC score	0.407861 (rank : 95)
Query Neighborhood Hits	370	Target Neighborhood Hits	165	Shared Neighborhood Hits	134
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

PTN3_HUMAN
θ value	9.29e-05 (rank : 131)	NC score	0.169037 (rank : 210)
Query Neighborhood Hits	370	Target Neighborhood Hits	258	Shared Neighborhood Hits	118
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

WWTR1_MOUSE
θ value	9.29e-05 (rank : 132)	NC score	0.313962 (rank : 155)
Query Neighborhood Hits	370	Target Neighborhood Hits	54	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

ZO2_HUMAN
θ value	9.29e-05 (rank : 133)	NC score	0.488538 (rank : 73)
Query Neighborhood Hits	370	Target Neighborhood Hits	289	Shared Neighborhood Hits	180
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	9.29e-05 (rank : 134)	NC score	0.484734 (rank : 74)
Query Neighborhood Hits	370	Target Neighborhood Hits	296	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

MAST4_HUMAN
θ value	0.000121331 (rank : 135)	NC score	0.083590 (rank : 241)
Query Neighborhood Hits	370	Target Neighborhood Hits	1804	Shared Neighborhood Hits	190
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PDZD3_MOUSE
θ value	0.000121331 (rank : 136)	NC score	0.529461 (rank : 65)
Query Neighborhood Hits	370	Target Neighborhood Hits	171	Shared Neighborhood Hits	156
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SHAN2_HUMAN
θ value	0.000121331 (rank : 137)	NC score	0.336044 (rank : 126)
Query Neighborhood Hits	370	Target Neighborhood Hits	346	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PDLI7_HUMAN
θ value	0.000158464 (rank : 138)	NC score	0.250537 (rank : 189)
Query Neighborhood Hits	370	Target Neighborhood Hits	547	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDLI7_MOUSE
θ value	0.000158464 (rank : 139)	NC score	0.239023 (rank : 191)
Query Neighborhood Hits	370	Target Neighborhood Hits	279	Shared Neighborhood Hits	110
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SHAN2_MOUSE
θ value	0.000158464 (rank : 140)	NC score	0.303447 (rank : 161)
Query Neighborhood Hits	370	Target Neighborhood Hits	446	Shared Neighborhood Hits	135
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

APXL_HUMAN
θ value	0.00020696 (rank : 141)	NC score	0.335535 (rank : 127)
Query Neighborhood Hits	370	Target Neighborhood Hits	553	Shared Neighborhood Hits	120
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PDLI3_HUMAN
θ value	0.00020696 (rank : 142)	NC score	0.329823 (rank : 132)
Query Neighborhood Hits	370	Target Neighborhood Hits	199	Shared Neighborhood Hits	110
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

APBA2_HUMAN
θ value	0.000270298 (rank : 143)	NC score	0.402218 (rank : 103)
Query Neighborhood Hits	370	Target Neighborhood Hits	220	Shared Neighborhood Hits	148
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.000270298 (rank : 144)	NC score	0.401469 (rank : 105)
Query Neighborhood Hits	370	Target Neighborhood Hits	219	Shared Neighborhood Hits	148
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

LRRC7_HUMAN
θ value	0.000270298 (rank : 145)	NC score	0.218096 (rank : 194)
Query Neighborhood Hits	370	Target Neighborhood Hits	423	Shared Neighborhood Hits	121
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.000270298 (rank : 146)	NC score	0.217149 (rank : 195)
Query Neighborhood Hits	370	Target Neighborhood Hits	416	Shared Neighborhood Hits	121
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PCLO_MOUSE
θ value	0.000270298 (rank : 147)	NC score	0.208420 (rank : 198)
Query Neighborhood Hits	370	Target Neighborhood Hits	2275	Shared Neighborhood Hits	223
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

IL16_MOUSE
θ value	0.00035302 (rank : 148)	NC score	0.555589 (rank : 57)
Query Neighborhood Hits	370	Target Neighborhood Hits	189	Shared Neighborhood Hits	143
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

MPP3_HUMAN
θ value	0.00035302 (rank : 149)	NC score	0.402384 (rank : 102)
Query Neighborhood Hits	370	Target Neighborhood Hits	171	Shared Neighborhood Hits	134
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MAST1_HUMAN
θ value	0.000461057 (rank : 150)	NC score	0.077459 (rank : 250)
Query Neighborhood Hits	370	Target Neighborhood Hits	1146	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	0.000461057 (rank : 151)	NC score	0.078424 (rank : 248)
Query Neighborhood Hits	370	Target Neighborhood Hits	1123	Shared Neighborhood Hits	142
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

LAP2_HUMAN
θ value	0.000602161 (rank : 152)	NC score	0.199025 (rank : 199)
Query Neighborhood Hits	370	Target Neighborhood Hits	499	Shared Neighborhood Hits	114
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MAST2_HUMAN
θ value	0.000602161 (rank : 153)	NC score	0.078231 (rank : 249)
Query Neighborhood Hits	370	Target Neighborhood Hits	1189	Shared Neighborhood Hits	142
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	0.000602161 (rank : 154)	NC score	0.076064 (rank : 251)
Query Neighborhood Hits	370	Target Neighborhood Hits	1110	Shared Neighborhood Hits	137
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PSCBP_HUMAN
θ value	0.000602161 (rank : 155)	NC score	0.391327 (rank : 108)
Query Neighborhood Hits	370	Target Neighborhood Hits	123	Shared Neighborhood Hits	114
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

EM55_HUMAN
θ value	0.000786445 (rank : 156)	NC score	0.376296 (rank : 110)
Query Neighborhood Hits	370	Target Neighborhood Hits	228	Shared Neighborhood Hits	130
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

PSCBP_MOUSE
θ value	0.000786445 (rank : 157)	NC score	0.405708 (rank : 97)
Query Neighborhood Hits	370	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RGS3_HUMAN
θ value	0.000786445 (rank : 158)	NC score	0.114911 (rank : 228)
Query Neighborhood Hits	370	Target Neighborhood Hits	1375	Shared Neighborhood Hits	139
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

EM55_MOUSE
θ value	0.00102713 (rank : 159)	NC score	0.371897 (rank : 112)
Query Neighborhood Hits	370	Target Neighborhood Hits	221	Shared Neighborhood Hits	128
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

RHPN1_MOUSE
θ value	0.00102713 (rank : 160)	NC score	0.360307 (rank : 118)
Query Neighborhood Hits	370	Target Neighborhood Hits	154	Shared Neighborhood Hits	132
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GIPC1_MOUSE
θ value	0.00134147 (rank : 161)	NC score	0.278264 (rank : 175)
Query Neighborhood Hits	370	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

MPP5_HUMAN
θ value	0.00134147 (rank : 162)	NC score	0.403320 (rank : 99)
Query Neighborhood Hits	370	Target Neighborhood Hits	231	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP6_MOUSE
θ value	0.00134147 (rank : 163)	NC score	0.331338 (rank : 130)
Query Neighborhood Hits	370	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

GIPC1_HUMAN
θ value	0.00175202 (rank : 164)	NC score	0.266636 (rank : 181)
Query Neighborhood Hits	370	Target Neighborhood Hits	91	Shared Neighborhood Hits	88
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

MPP5_MOUSE
θ value	0.00175202 (rank : 165)	NC score	0.401752 (rank : 104)
Query Neighborhood Hits	370	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP6_HUMAN
θ value	0.00298849 (rank : 166)	NC score	0.326228 (rank : 140)
Query Neighborhood Hits	370	Target Neighborhood Hits	180	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP2_HUMAN
θ value	0.00390308 (rank : 167)	NC score	0.323800 (rank : 142)
Query Neighborhood Hits	370	Target Neighborhood Hits	173	Shared Neighborhood Hits	96
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

PAR6G_MOUSE
θ value	0.00390308 (rank : 168)	NC score	0.342949 (rank : 121)
Query Neighborhood Hits	370	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PDZK4_MOUSE
θ value	0.00390308 (rank : 169)	NC score	0.363253 (rank : 116)
Query Neighborhood Hits	370	Target Neighborhood Hits	165	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

MPP2_MOUSE
θ value	0.00509761 (rank : 170)	NC score	0.326842 (rank : 139)
Query Neighborhood Hits	370	Target Neighborhood Hits	189	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MY18A_MOUSE
θ value	0.00509761 (rank : 171)	NC score	0.080106 (rank : 244)
Query Neighborhood Hits	370	Target Neighborhood Hits	1989	Shared Neighborhood Hits	170
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TX1B3_HUMAN
θ value	0.00509761 (rank : 172)	NC score	0.555829 (rank : 56)
Query Neighborhood Hits	370	Target Neighborhood Hits	161	Shared Neighborhood Hits	153
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.00509761 (rank : 173)	NC score	0.552114 (rank : 61)
Query Neighborhood Hits	370	Target Neighborhood Hits	158	Shared Neighborhood Hits	150
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PDLI4_HUMAN
θ value	0.00665767 (rank : 174)	NC score	0.317346 (rank : 153)
Query Neighborhood Hits	370	Target Neighborhood Hits	245	Shared Neighborhood Hits	113
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

KGUA_HUMAN
θ value	0.00869519 (rank : 175)	NC score	0.272969 (rank : 177)
Query Neighborhood Hits	370	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LIMK1_MOUSE
θ value	0.00869519 (rank : 176)	NC score	0.042138 (rank : 297)
Query Neighborhood Hits	370	Target Neighborhood Hits	1008	Shared Neighborhood Hits	92
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

PDLI1_HUMAN
θ value	0.00869519 (rank : 177)	NC score	0.313841 (rank : 156)
Query Neighborhood Hits	370	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	0.00869519 (rank : 178)	NC score	0.320408 (rank : 149)
Query Neighborhood Hits	370	Target Neighborhood Hits	213	Shared Neighborhood Hits	107
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

RPGF6_HUMAN
θ value	0.00869519 (rank : 179)	NC score	0.335325 (rank : 128)
Query Neighborhood Hits	370	Target Neighborhood Hits	266	Shared Neighborhood Hits	154
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

AFAD_HUMAN
θ value	0.0113563 (rank : 180)	NC score	0.400181 (rank : 106)
Query Neighborhood Hits	370	Target Neighborhood Hits	689	Shared Neighborhood Hits	154
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

DLG5_HUMAN
θ value	0.0113563 (rank : 181)	NC score	0.362780 (rank : 117)
Query Neighborhood Hits	370	Target Neighborhood Hits	1088	Shared Neighborhood Hits	203
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PDLI4_MOUSE
θ value	0.0113563 (rank : 182)	NC score	0.316458 (rank : 154)
Query Neighborhood Hits	370	Target Neighborhood Hits	233	Shared Neighborhood Hits	115
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDZK4_HUMAN
θ value	0.0113563 (rank : 183)	NC score	0.365945 (rank : 114)
Query Neighborhood Hits	370	Target Neighborhood Hits	165	Shared Neighborhood Hits	116
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

ARI1A_HUMAN
θ value	0.0193708 (rank : 184)	NC score	0.050117 (rank : 282)
Query Neighborhood Hits	370	Target Neighborhood Hits	787	Shared Neighborhood Hits	68
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CNKR1_HUMAN
θ value	0.0193708 (rank : 185)	NC score	0.115708 (rank : 227)
Query Neighborhood Hits	370	Target Neighborhood Hits	154	Shared Neighborhood Hits	20
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

DVL1L_HUMAN
θ value	0.0193708 (rank : 186)	NC score	0.330263 (rank : 131)
Query Neighborhood Hits	370	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL3_HUMAN
θ value	0.0193708 (rank : 187)	NC score	0.344708 (rank : 119)
Query Neighborhood Hits	370	Target Neighborhood Hits	194	Shared Neighborhood Hits	121
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	0.0193708 (rank : 188)	NC score	0.344619 (rank : 120)
Query Neighborhood Hits	370	Target Neighborhood Hits	198	Shared Neighborhood Hits	120
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

GIPC2_HUMAN
θ value	0.0193708 (rank : 189)	NC score	0.228621 (rank : 193)
Query Neighborhood Hits	370	Target Neighborhood Hits	93	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

GRASP_HUMAN
θ value	0.0193708 (rank : 190)	NC score	0.409976 (rank : 92)
Query Neighborhood Hits	370	Target Neighborhood Hits	147	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

MPP4_HUMAN
θ value	0.0193708 (rank : 191)	NC score	0.413156 (rank : 89)
Query Neighborhood Hits	370	Target Neighborhood Hits	205	Shared Neighborhood Hits	142
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDLI3_MOUSE
θ value	0.0193708 (rank : 192)	NC score	0.304886 (rank : 160)
Query Neighborhood Hits	370	Target Neighborhood Hits	197	Shared Neighborhood Hits	106
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

BRD4_HUMAN
θ value	0.0252991 (rank : 193)	NC score	0.046161 (rank : 292)
Query Neighborhood Hits	370	Target Neighborhood Hits	851	Shared Neighborhood Hits	73
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DVL1_MOUSE
θ value	0.0252991 (rank : 194)	NC score	0.339718 (rank : 123)
Query Neighborhood Hits	370	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GRASP_MOUSE
θ value	0.0252991 (rank : 195)	NC score	0.409596 (rank : 93)
Query Neighborhood Hits	370	Target Neighborhood Hits	131	Shared Neighborhood Hits	117
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

NOS1_HUMAN
θ value	0.0252991 (rank : 196)	NC score	0.268580 (rank : 180)
Query Neighborhood Hits	370	Target Neighborhood Hits	218	Shared Neighborhood Hits	140
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

DVL1_HUMAN
θ value	0.0330416 (rank : 197)	NC score	0.342550 (rank : 122)
Query Neighborhood Hits	370	Target Neighborhood Hits	158	Shared Neighborhood Hits	119
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

HNRL1_HUMAN
θ value	0.0330416 (rank : 198)	NC score	0.050153 (rank : 281)
Query Neighborhood Hits	370	Target Neighborhood Hits	173	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
θ value	0.0330416 (rank : 199)	NC score	0.058369 (rank : 271)
Query Neighborhood Hits	370	Target Neighborhood Hits	200	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

LAP2_MOUSE
θ value	0.0330416 (rank : 200)	NC score	0.187108 (rank : 203)
Query Neighborhood Hits	370	Target Neighborhood Hits	482	Shared Neighborhood Hits	115
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

RGS3_MOUSE
θ value	0.0330416 (rank : 201)	NC score	0.102498 (rank : 234)
Query Neighborhood Hits	370	Target Neighborhood Hits	1621	Shared Neighborhood Hits	156
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHPN1_HUMAN
θ value	0.0330416 (rank : 202)	NC score	0.317356 (rank : 152)
Query Neighborhood Hits	370	Target Neighborhood Hits	158	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GIPC2_MOUSE
θ value	0.0431538 (rank : 203)	NC score	0.175093 (rank : 205)
Query Neighborhood Hits	370	Target Neighborhood Hits	71	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

KGUA_MOUSE
θ value	0.0431538 (rank : 204)	NC score	0.270030 (rank : 179)
Query Neighborhood Hits	370	Target Neighborhood Hits	45	Shared Neighborhood Hits	31
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

PAR6G_HUMAN
θ value	0.0431538 (rank : 205)	NC score	0.333086 (rank : 129)
Query Neighborhood Hits	370	Target Neighborhood Hits	159	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

RGS12_HUMAN
θ value	0.0431538 (rank : 206)	NC score	0.278789 (rank : 174)
Query Neighborhood Hits	370	Target Neighborhood Hits	333	Shared Neighborhood Hits	144
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

GIPC3_HUMAN
θ value	0.0563607 (rank : 207)	NC score	0.179296 (rank : 204)
Query Neighborhood Hits	370	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	0.0563607 (rank : 208)	NC score	0.172688 (rank : 207)
Query Neighborhood Hits	370	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

MAGD1_MOUSE
θ value	0.0563607 (rank : 209)	NC score	0.025649 (rank : 328)
Query Neighborhood Hits	370	Target Neighborhood Hits	136	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYH6, Q543L6, Q99PB5, Q9CYX1	Gene names	Maged1, Nrage
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (Dlxin-1).

MY18A_HUMAN
θ value	0.0563607 (rank : 210)	NC score	0.070935 (rank : 254)
Query Neighborhood Hits	370	Target Neighborhood Hits	1929	Shared Neighborhood Hits	171
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

DVL2_HUMAN
θ value	0.0736092 (rank : 211)	NC score	0.323490 (rank : 143)
Query Neighborhood Hits	370	Target Neighborhood Hits	223	Shared Neighborhood Hits	121
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	0.0736092 (rank : 212)	NC score	0.321878 (rank : 144)
Query Neighborhood Hits	370	Target Neighborhood Hits	233	Shared Neighborhood Hits	120
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PAR6A_MOUSE
θ value	0.0736092 (rank : 213)	NC score	0.321556 (rank : 147)
Query Neighborhood Hits	370	Target Neighborhood Hits	115	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PTN23_MOUSE
θ value	0.0736092 (rank : 214)	NC score	0.060086 (rank : 264)
Query Neighborhood Hits	370	Target Neighborhood Hits	726	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

STRC_MOUSE
θ value	0.0736092 (rank : 215)	NC score	0.030899 (rank : 322)
Query Neighborhood Hits	370	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

ATBF1_HUMAN
θ value	0.0961366 (rank : 216)	NC score	0.007033 (rank : 384)
Query Neighborhood Hits	370	Target Neighborhood Hits	1547	Shared Neighborhood Hits	53
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

MINT_HUMAN
θ value	0.0961366 (rank : 217)	NC score	0.037205 (rank : 309)
Query Neighborhood Hits	370	Target Neighborhood Hits	1291	Shared Neighborhood Hits	83
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOR2_MOUSE
θ value	0.0961366 (rank : 218)	NC score	0.047539 (rank : 291)
Query Neighborhood Hits	370	Target Neighborhood Hits	790	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

LIMK1_HUMAN
θ value	0.125558 (rank : 219)	NC score	0.041484 (rank : 300)
Query Neighborhood Hits	370	Target Neighborhood Hits	1005	Shared Neighborhood Hits	89
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

MPP4_MOUSE
θ value	0.125558 (rank : 220)	NC score	0.377739 (rank : 109)
Query Neighborhood Hits	370	Target Neighborhood Hits	188	Shared Neighborhood Hits	123
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

BRD4_MOUSE
θ value	0.163984 (rank : 221)	NC score	0.041406 (rank : 301)
Query Neighborhood Hits	370	Target Neighborhood Hits	845	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MDC1_HUMAN
θ value	0.163984 (rank : 222)	NC score	0.062337 (rank : 262)
Query Neighborhood Hits	370	Target Neighborhood Hits	1446	Shared Neighborhood Hits	108
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

AFF1_HUMAN
θ value	0.21417 (rank : 223)	NC score	0.049723 (rank : 285)
Query Neighborhood Hits	370	Target Neighborhood Hits	506	Shared Neighborhood Hits	49
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CBP_MOUSE
θ value	0.21417 (rank : 224)	NC score	0.059769 (rank : 267)
Query Neighborhood Hits	370	Target Neighborhood Hits	1051	Shared Neighborhood Hits	87
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PAR6A_HUMAN
θ value	0.21417 (rank : 225)	NC score	0.317879 (rank : 151)
Query Neighborhood Hits	370	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PCLO_HUMAN
θ value	0.21417 (rank : 226)	NC score	0.065979 (rank : 259)
Query Neighborhood Hits	370	Target Neighborhood Hits	2046	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SETD2_HUMAN
θ value	0.279714 (rank : 227)	NC score	0.075290 (rank : 253)
Query Neighborhood Hits	370	Target Neighborhood Hits	412	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

CPSF6_HUMAN
θ value	0.365318 (rank : 228)	NC score	0.041246 (rank : 302)
Query Neighborhood Hits	370	Target Neighborhood Hits	359	Shared Neighborhood Hits	34
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	0.365318 (rank : 229)	NC score	0.041689 (rank : 299)
Query Neighborhood Hits	370	Target Neighborhood Hits	356	Shared Neighborhood Hits	35
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

LR37A_HUMAN
θ value	0.365318 (rank : 230)	NC score	0.032698 (rank : 318)
Query Neighborhood Hits	370	Target Neighborhood Hits	720	Shared Neighborhood Hits	52
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NOS1_MOUSE
θ value	0.365318 (rank : 231)	NC score	0.234669 (rank : 192)
Query Neighborhood Hits	370	Target Neighborhood Hits	155	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

RIMS2_HUMAN
θ value	0.365318 (rank : 232)	NC score	0.189611 (rank : 201)
Query Neighborhood Hits	370	Target Neighborhood Hits	342	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.365318 (rank : 233)	NC score	0.189343 (rank : 202)
Query Neighborhood Hits	370	Target Neighborhood Hits	376	Shared Neighborhood Hits	122
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RPGF2_HUMAN
θ value	0.365318 (rank : 234)	NC score	0.282446 (rank : 172)
Query Neighborhood Hits	370	Target Neighborhood Hits	242	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

CBP_HUMAN
θ value	0.47712 (rank : 235)	NC score	0.056620 (rank : 273)
Query Neighborhood Hits	370	Target Neighborhood Hits	941	Shared Neighborhood Hits	86
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

K2C1_MOUSE
θ value	0.47712 (rank : 236)	NC score	0.007470 (rank : 381)
Query Neighborhood Hits	370	Target Neighborhood Hits	477	Shared Neighborhood Hits	15
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

SDCB1_MOUSE
θ value	0.47712 (rank : 237)	NC score	0.321364 (rank : 148)
Query Neighborhood Hits	370	Target Neighborhood Hits	144	Shared Neighborhood Hits	134
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

TARSH_HUMAN
θ value	0.47712 (rank : 238)	NC score	0.048760 (rank : 287)
Query Neighborhood Hits	370	Target Neighborhood Hits	768	Shared Neighborhood Hits	81
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

K1688_HUMAN
θ value	0.62314 (rank : 239)	NC score	0.032764 (rank : 316)
Query Neighborhood Hits	370	Target Neighborhood Hits	217	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K2C3_HUMAN
θ value	0.62314 (rank : 240)	NC score	0.007976 (rank : 379)
Query Neighborhood Hits	370	Target Neighborhood Hits	443	Shared Neighborhood Hits	13
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

MA1B1_HUMAN
θ value	0.62314 (rank : 241)	NC score	0.022609 (rank : 336)
Query Neighborhood Hits	370	Target Neighborhood Hits	125	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

PAR6B_HUMAN
θ value	0.62314 (rank : 242)	NC score	0.329036 (rank : 134)
Query Neighborhood Hits	370	Target Neighborhood Hits	126	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	0.62314 (rank : 243)	NC score	0.327820 (rank : 137)
Query Neighborhood Hits	370	Target Neighborhood Hits	128	Shared Neighborhood Hits	121
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PDZD6_HUMAN
θ value	0.62314 (rank : 244)	NC score	0.163550 (rank : 211)
Query Neighborhood Hits	370	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

ROBO1_MOUSE
θ value	0.62314 (rank : 245)	NC score	0.003236 (rank : 400)
Query Neighborhood Hits	370	Target Neighborhood Hits	559	Shared Neighborhood Hits	17
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

SAPS1_HUMAN
θ value	0.62314 (rank : 246)	NC score	0.038952 (rank : 305)
Query Neighborhood Hits	370	Target Neighborhood Hits	704	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CASC3_MOUSE
θ value	0.813845 (rank : 247)	NC score	0.041934 (rank : 298)
Query Neighborhood Hits	370	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

NFH_MOUSE
θ value	0.813845 (rank : 248)	NC score	0.048035 (rank : 289)
Query Neighborhood Hits	370	Target Neighborhood Hits	2247	Shared Neighborhood Hits	125
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PDC6I_MOUSE
θ value	0.813845 (rank : 249)	NC score	0.038165 (rank : 307)
Query Neighborhood Hits	370	Target Neighborhood Hits	275	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

SDCB2_MOUSE
θ value	0.813845 (rank : 250)	NC score	0.281076 (rank : 173)
Query Neighborhood Hits	370	Target Neighborhood Hits	118	Shared Neighborhood Hits	111
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

CIC_HUMAN
θ value	1.06291 (rank : 251)	NC score	0.040846 (rank : 303)
Query Neighborhood Hits	370	Target Neighborhood Hits	992	Shared Neighborhood Hits	86
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FUBP3_HUMAN
θ value	1.06291 (rank : 252)	NC score	0.011287 (rank : 372)
Query Neighborhood Hits	370	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

LHX3_MOUSE
θ value	1.06291 (rank : 253)	NC score	0.028401 (rank : 325)
Query Neighborhood Hits	370	Target Neighborhood Hits	451	Shared Neighborhood Hits	21
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

ETV6_HUMAN
θ value	1.38821 (rank : 254)	NC score	0.014738 (rank : 362)
Query Neighborhood Hits	370	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

IRS2_HUMAN
θ value	1.38821 (rank : 255)	NC score	0.032746 (rank : 317)
Query Neighborhood Hits	370	Target Neighborhood Hits	262	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MAML1_HUMAN
θ value	1.38821 (rank : 256)	NC score	0.019328 (rank : 346)
Query Neighborhood Hits	370	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PI5PA_MOUSE
θ value	1.38821 (rank : 257)	NC score	0.024851 (rank : 330)
Query Neighborhood Hits	370	Target Neighborhood Hits	331	Shared Neighborhood Hits	43
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RHG12_HUMAN
θ value	1.38821 (rank : 258)	NC score	0.049909 (rank : 283)
Query Neighborhood Hits	370	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	1.38821 (rank : 259)	NC score	0.056313 (rank : 274)
Query Neighborhood Hits	370	Target Neighborhood Hits	204	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SDCB2_HUMAN
θ value	1.38821 (rank : 260)	NC score	0.270203 (rank : 178)
Query Neighborhood Hits	370	Target Neighborhood Hits	121	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

ACD_HUMAN
θ value	1.81305 (rank : 261)	NC score	0.031197 (rank : 321)
Query Neighborhood Hits	370	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

HKR3_HUMAN
θ value	1.81305 (rank : 262)	NC score	-0.009326 (rank : 412)
Query Neighborhood Hits	370	Target Neighborhood Hits	839	Shared Neighborhood Hits	13
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).

NCOR2_HUMAN
θ value	1.81305 (rank : 263)	NC score	0.048713 (rank : 288)
Query Neighborhood Hits	370	Target Neighborhood Hits	870	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PRD16_HUMAN
θ value	1.81305 (rank : 264)	NC score	-0.008208 (rank : 411)
Query Neighborhood Hits	370	Target Neighborhood Hits	832	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

RFX1_HUMAN
θ value	1.81305 (rank : 265)	NC score	0.017039 (rank : 353)
Query Neighborhood Hits	370	Target Neighborhood Hits	256	Shared Neighborhood Hits	32
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RIMS1_HUMAN
θ value	1.81305 (rank : 266)	NC score	0.212715 (rank : 196)
Query Neighborhood Hits	370	Target Neighborhood Hits	437	Shared Neighborhood Hits	144
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SELPL_MOUSE
θ value	1.81305 (rank : 267)	NC score	0.049132 (rank : 286)
Query Neighborhood Hits	370	Target Neighborhood Hits	588	Shared Neighborhood Hits	64
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

VCY1_HUMAN
θ value	1.81305 (rank : 268)	NC score	0.083453 (rank : 242)
Query Neighborhood Hits	370	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

CLSPN_MOUSE
θ value	2.36792 (rank : 269)	NC score	0.016807 (rank : 355)
Query Neighborhood Hits	370	Target Neighborhood Hits	292	Shared Neighborhood Hits	12
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

EP300_HUMAN
θ value	2.36792 (rank : 270)	NC score	0.042551 (rank : 296)
Query Neighborhood Hits	370	Target Neighborhood Hits	821	Shared Neighborhood Hits	74
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

M3K6_HUMAN
θ value	2.36792 (rank : 271)	NC score	0.005135 (rank : 391)
Query Neighborhood Hits	370	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

S13A3_MOUSE
θ value	2.36792 (rank : 272)	NC score	0.013458 (rank : 367)
Query Neighborhood Hits	370	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Y63	Gene names	Slc13a3, Nadc3, Sdct2
Domain Architecture
Description	Solute carrier family 13 member 3 (Sodium-dependent high-affinity dicarboxylate transporter 2) (Na(+)/dicarboxylate cotransporter 3) (NaDC-3) (mNaDC3).

SIG10_HUMAN
θ value	2.36792 (rank : 273)	NC score	0.004509 (rank : 394)
Query Neighborhood Hits	370	Target Neighborhood Hits	363	Shared Neighborhood Hits	19
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SYN1_HUMAN
θ value	2.36792 (rank : 274)	NC score	0.034104 (rank : 314)
Query Neighborhood Hits	370	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

ABLM3_MOUSE
θ value	3.0926 (rank : 275)	NC score	0.044009 (rank : 294)
Query Neighborhood Hits	370	Target Neighborhood Hits	294	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

CD2_HUMAN
θ value	3.0926 (rank : 276)	NC score	0.029811 (rank : 324)
Query Neighborhood Hits	370	Target Neighborhood Hits	504	Shared Neighborhood Hits	53
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

DRP2_HUMAN
θ value	3.0926 (rank : 277)	NC score	0.047675 (rank : 290)
Query Neighborhood Hits	370	Target Neighborhood Hits	186	Shared Neighborhood Hits	26
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

EPHB3_MOUSE
θ value	3.0926 (rank : 278)	NC score	0.000801 (rank : 405)
Query Neighborhood Hits	370	Target Neighborhood Hits	996	Shared Neighborhood Hits	29
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

G3PT_MOUSE
θ value	3.0926 (rank : 279)	NC score	0.022718 (rank : 335)
Query Neighborhood Hits	370	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

HRX_HUMAN
θ value	3.0926 (rank : 280)	NC score	0.020033 (rank : 342)
Query Neighborhood Hits	370	Target Neighborhood Hits	825	Shared Neighborhood Hits	54
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

M3K10_HUMAN
θ value	3.0926 (rank : 281)	NC score	0.004097 (rank : 396)
Query Neighborhood Hits	370	Target Neighborhood Hits	1071	Shared Neighborhood Hits	33
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MAGA8_HUMAN
θ value	3.0926 (rank : 282)	NC score	0.007239 (rank : 383)
Query Neighborhood Hits	370	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	P43361	Gene names	MAGEA8, MAGE8
Domain Architecture
Description	Melanoma-associated antigen 8 (MAGE-8 antigen).

MINK1_HUMAN
θ value	3.0926 (rank : 283)	NC score	0.005465 (rank : 390)
Query Neighborhood Hits	370	Target Neighborhood Hits	1477	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MLL2_HUMAN
θ value	3.0926 (rank : 284)	NC score	0.033305 (rank : 315)
Query Neighborhood Hits	370	Target Neighborhood Hits	1788	Shared Neighborhood Hits	104
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MMAC_HUMAN
θ value	3.0926 (rank : 285)	NC score	0.017013 (rank : 354)
Query Neighborhood Hits	370	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4U1, Q5T157, Q9BRQ7	Gene names	MMACHC
Domain Architecture	No domain graphic available
Description	Methylmalonic aciduria and homocystinuria type C protein.

PAPOG_HUMAN
θ value	3.0926 (rank : 286)	NC score	0.008048 (rank : 378)
Query Neighborhood Hits	370	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

PINL_HUMAN
θ value	3.0926 (rank : 287)	NC score	0.198748 (rank : 200)
Query Neighborhood Hits	370	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

RERE_HUMAN
θ value	3.0926 (rank : 288)	NC score	0.029949 (rank : 323)
Query Neighborhood Hits	370	Target Neighborhood Hits	779	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

5NT1B_MOUSE
θ value	4.03905 (rank : 289)	NC score	0.014178 (rank : 365)
Query Neighborhood Hits	370	Target Neighborhood Hits	78	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

ANK2_HUMAN
θ value	4.03905 (rank : 290)	NC score	0.024612 (rank : 333)
Query Neighborhood Hits	370	Target Neighborhood Hits	1615	Shared Neighborhood Hits	105
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BAZ2A_HUMAN
θ value	4.03905 (rank : 291)	NC score	0.024790 (rank : 331)
Query Neighborhood Hits	370	Target Neighborhood Hits	780	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BCL7A_MOUSE
θ value	4.03905 (rank : 292)	NC score	0.014350 (rank : 363)
Query Neighborhood Hits	370	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

CD2L7_HUMAN
θ value	4.03905 (rank : 293)	NC score	0.007019 (rank : 385)
Query Neighborhood Hits	370	Target Neighborhood Hits	1275	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

DMD_HUMAN
θ value	4.03905 (rank : 294)	NC score	0.026633 (rank : 326)
Query Neighborhood Hits	370	Target Neighborhood Hits	1135	Shared Neighborhood Hits	55
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	4.03905 (rank : 295)	NC score	0.024789 (rank : 332)
Query Neighborhood Hits	370	Target Neighborhood Hits	1111	Shared Neighborhood Hits	56
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

GAS7_HUMAN
θ value	4.03905 (rank : 296)	NC score	0.106757 (rank : 232)
Query Neighborhood Hits	370	Target Neighborhood Hits	258	Shared Neighborhood Hits	44
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GP137_MOUSE
θ value	4.03905 (rank : 297)	NC score	0.021544 (rank : 338)
Query Neighborhood Hits	370	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q60865, Q60758, Q61620	Gene names	M11s1, Gpiap, Gpiap1, Gpip137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI).

JPH2_HUMAN
θ value	4.03905 (rank : 298)	NC score	0.019926 (rank : 343)
Query Neighborhood Hits	370	Target Neighborhood Hits	639	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K2C6B_MOUSE
θ value	4.03905 (rank : 299)	NC score	0.003457 (rank : 399)
Query Neighborhood Hits	370	Target Neighborhood Hits	506	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

MAGD1_HUMAN
θ value	4.03905 (rank : 300)	NC score	0.020238 (rank : 341)
Query Neighborhood Hits	370	Target Neighborhood Hits	130	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

MBD6_HUMAN
θ value	4.03905 (rank : 301)	NC score	0.032180 (rank : 319)
Query Neighborhood Hits	370	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MKL1_HUMAN
θ value	4.03905 (rank : 302)	NC score	0.018656 (rank : 350)
Query Neighborhood Hits	370	Target Neighborhood Hits	232	Shared Neighborhood Hits	31
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

NCOA6_MOUSE
θ value	4.03905 (rank : 303)	NC score	0.035241 (rank : 311)
Query Neighborhood Hits	370	Target Neighborhood Hits	1076	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PABP1_HUMAN
θ value	4.03905 (rank : 304)	NC score	0.003848 (rank : 398)
Query Neighborhood Hits	370	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_MOUSE
θ value	4.03905 (rank : 305)	NC score	0.004339 (rank : 395)
Query Neighborhood Hits	370	Target Neighborhood Hits	278	Shared Neighborhood Hits	19
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

SDCB1_HUMAN
θ value	4.03905 (rank : 306)	NC score	0.309761 (rank : 158)
Query Neighborhood Hits	370	Target Neighborhood Hits	150	Shared Neighborhood Hits	140
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SRRM2_HUMAN
θ value	4.03905 (rank : 307)	NC score	0.068128 (rank : 257)
Query Neighborhood Hits	370	Target Neighborhood Hits	1296	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

UTRO_HUMAN
θ value	4.03905 (rank : 308)	NC score	0.021694 (rank : 337)
Query Neighborhood Hits	370	Target Neighborhood Hits	960	Shared Neighborhood Hits	46
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

WASF2_MOUSE
θ value	4.03905 (rank : 309)	NC score	0.023563 (rank : 334)
Query Neighborhood Hits	370	Target Neighborhood Hits	315	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WIRE_HUMAN
θ value	4.03905 (rank : 310)	NC score	0.038882 (rank : 306)
Query Neighborhood Hits	370	Target Neighborhood Hits	329	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WNK2_HUMAN
θ value	4.03905 (rank : 311)	NC score	0.013704 (rank : 366)
Query Neighborhood Hits	370	Target Neighborhood Hits	1407	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZN645_HUMAN
θ value	4.03905 (rank : 312)	NC score	0.026354 (rank : 327)
Query Neighborhood Hits	370	Target Neighborhood Hits	265	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

AB1IP_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.014932 (rank : 359)
Query Neighborhood Hits	370	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ABLM3_HUMAN
θ value	5.27518 (rank : 314)	NC score	0.042848 (rank : 295)
Query Neighborhood Hits	370	Target Neighborhood Hits	293	Shared Neighborhood Hits	27
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ANGL6_HUMAN
θ value	5.27518 (rank : 315)	NC score	0.004884 (rank : 392)
Query Neighborhood Hits	370	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

CDN1C_MOUSE
θ value	5.27518 (rank : 316)	NC score	0.019126 (rank : 348)
Query Neighborhood Hits	370	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CEP72_HUMAN
θ value	5.27518 (rank : 317)	NC score	0.010398 (rank : 373)
Query Neighborhood Hits	370	Target Neighborhood Hits	374	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CN037_MOUSE
θ value	5.27518 (rank : 318)	NC score	0.017934 (rank : 351)
Query Neighborhood Hits	370	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

DGCR8_HUMAN
θ value	5.27518 (rank : 319)	NC score	0.037119 (rank : 310)
Query Neighborhood Hits	370	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

DGCR8_MOUSE
θ value	5.27518 (rank : 320)	NC score	0.037835 (rank : 308)
Query Neighborhood Hits	370	Target Neighborhood Hits	70	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

HGS_MOUSE
θ value	5.27518 (rank : 321)	NC score	0.019286 (rank : 347)
Query Neighborhood Hits	370	Target Neighborhood Hits	589	Shared Neighborhood Hits	51
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

LRP2_HUMAN
θ value	5.27518 (rank : 322)	NC score	-0.003550 (rank : 408)
Query Neighborhood Hits	370	Target Neighborhood Hits	573	Shared Neighborhood Hits	8
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LTBP3_HUMAN
θ value	5.27518 (rank : 323)	NC score	-0.003687 (rank : 409)
Query Neighborhood Hits	370	Target Neighborhood Hits	502	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MBB1A_MOUSE
θ value	5.27518 (rank : 324)	NC score	0.012303 (rank : 370)
Query Neighborhood Hits	370	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

MBD1_MOUSE
θ value	5.27518 (rank : 325)	NC score	0.007854 (rank : 380)
Query Neighborhood Hits	370	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

NACAM_MOUSE
θ value	5.27518 (rank : 326)	NC score	0.053385 (rank : 277)
Query Neighborhood Hits	370	Target Neighborhood Hits	1866	Shared Neighborhood Hits	123
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PIN1_HUMAN
θ value	5.27518 (rank : 327)	NC score	0.171343 (rank : 208)
Query Neighborhood Hits	370	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	5.27518 (rank : 328)	NC score	0.173154 (rank : 206)
Query Neighborhood Hits	370	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

RBM6_HUMAN
θ value	5.27518 (rank : 329)	NC score	0.016435 (rank : 357)
Query Neighborhood Hits	370	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

RTP3_MOUSE
θ value	5.27518 (rank : 330)	NC score	0.025587 (rank : 329)
Query Neighborhood Hits	370	Target Neighborhood Hits	374	Shared Neighborhood Hits	44
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SFR15_HUMAN
θ value	5.27518 (rank : 331)	NC score	0.020989 (rank : 340)
Query Neighborhood Hits	370	Target Neighborhood Hits	368	Shared Neighborhood Hits	33
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SPF45_HUMAN
θ value	5.27518 (rank : 332)	NC score	0.015450 (rank : 358)
Query Neighborhood Hits	370	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

TLE3_HUMAN
θ value	5.27518 (rank : 333)	NC score	0.002658 (rank : 402)
Query Neighborhood Hits	370	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

USP9X_HUMAN
θ value	5.27518 (rank : 334)	NC score	0.009522 (rank : 374)
Query Neighborhood Hits	370	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	5.27518 (rank : 335)	NC score	0.009477 (rank : 375)
Query Neighborhood Hits	370	Target Neighborhood Hits	171	Shared Neighborhood Hits	11
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

WIRE_MOUSE
θ value	5.27518 (rank : 336)	NC score	0.040332 (rank : 304)
Query Neighborhood Hits	370	Target Neighborhood Hits	310	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZBTB9_HUMAN
θ value	5.27518 (rank : 337)	NC score	-0.006692 (rank : 410)
Query Neighborhood Hits	370	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q96C00	Gene names	ZBTB9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

BAT2_HUMAN
θ value	6.88961 (rank : 338)	NC score	0.049821 (rank : 284)
Query Neighborhood Hits	370	Target Neighborhood Hits	931	Shared Neighborhood Hits	90
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CBLB_HUMAN
θ value	6.88961 (rank : 339)	NC score	0.011791 (rank : 371)
Query Neighborhood Hits	370	Target Neighborhood Hits	261	Shared Neighborhood Hits	15
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

DCDC2_MOUSE
θ value	6.88961 (rank : 340)	NC score	0.004072 (rank : 397)
Query Neighborhood Hits	370	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

EPHB3_HUMAN
θ value	6.88961 (rank : 341)	NC score	-0.000173 (rank : 406)
Query Neighborhood Hits	370	Target Neighborhood Hits	996	Shared Neighborhood Hits	25
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

GAS7_MOUSE
θ value	6.88961 (rank : 342)	NC score	0.101988 (rank : 235)
Query Neighborhood Hits	370	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

NUFP1_HUMAN
θ value	6.88961 (rank : 343)	NC score	0.017367 (rank : 352)
Query Neighborhood Hits	370	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PTPRJ_HUMAN
θ value	6.88961 (rank : 344)	NC score	0.031333 (rank : 320)
Query Neighborhood Hits	370	Target Neighborhood Hits	207	Shared Neighborhood Hits	13
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

ROBO1_HUMAN
θ value	6.88961 (rank : 345)	NC score	-0.000826 (rank : 407)
Query Neighborhood Hits	370	Target Neighborhood Hits	529	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

SAFB2_MOUSE
θ value	6.88961 (rank : 346)	NC score	0.008874 (rank : 377)
Query Neighborhood Hits	370	Target Neighborhood Hits	581	Shared Neighborhood Hits	22
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SMRA3_MOUSE
θ value	6.88961 (rank : 347)	NC score	0.012418 (rank : 369)
Query Neighborhood Hits	370	Target Neighborhood Hits	267	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

THAP7_MOUSE
θ value	6.88961 (rank : 348)	NC score	0.014756 (rank : 361)
Query Neighborhood Hits	370	Target Neighborhood Hits	64	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

TLE3_MOUSE
θ value	6.88961 (rank : 349)	NC score	0.001263 (rank : 404)
Query Neighborhood Hits	370	Target Neighborhood Hits	378	Shared Neighborhood Hits	11
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

VMD2_HUMAN
θ value	6.88961 (rank : 350)	NC score	0.004563 (rank : 393)
Query Neighborhood Hits	370	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	O76090, O75904, Q8IUR9, Q8IZ80	Gene names	VMD2
Domain Architecture
Description	Bestrophin-1 (Vitelliform macular dystrophy protein 2) (TU15B).

BCAR1_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.014835 (rank : 360)
Query Neighborhood Hits	370	Target Neighborhood Hits	438	Shared Neighborhood Hits	50
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CCDC9_MOUSE
θ value	8.99809 (rank : 352)	NC score	0.012713 (rank : 368)
Query Neighborhood Hits	370	Target Neighborhood Hits	196	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CDCP1_MOUSE
θ value	8.99809 (rank : 353)	NC score	0.005825 (rank : 386)
Query Neighborhood Hits	370	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U462, Q810J0, Q921M9	Gene names	Cdcp1
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (CD318 antigen).

CENPF_HUMAN
θ value	8.99809 (rank : 354)	NC score	0.005644 (rank : 388)
Query Neighborhood Hits	370	Target Neighborhood Hits	1932	Shared Neighborhood Hits	60
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DZIP1_HUMAN
θ value	8.99809 (rank : 355)	NC score	0.002694 (rank : 401)
Query Neighborhood Hits	370	Target Neighborhood Hits	675	Shared Neighborhood Hits	19
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

HTRA1_HUMAN
θ value	8.99809 (rank : 356)	NC score	0.045713 (rank : 293)
Query Neighborhood Hits	370	Target Neighborhood Hits	155	Shared Neighborhood Hits	46
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

IASPP_MOUSE
θ value	8.99809 (rank : 357)	NC score	0.014237 (rank : 364)
Query Neighborhood Hits	370	Target Neighborhood Hits	1024	Shared Neighborhood Hits	56
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KCNQ1_HUMAN
θ value	8.99809 (rank : 358)	NC score	0.002158 (rank : 403)
Query Neighborhood Hits	370	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

LEUK_MOUSE
θ value	8.99809 (rank : 359)	NC score	0.021095 (rank : 339)
Query Neighborhood Hits	370	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MYO5A_HUMAN
θ value	8.99809 (rank : 360)	NC score	0.007439 (rank : 382)
Query Neighborhood Hits	370	Target Neighborhood Hits	1092	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NOP14_HUMAN
θ value	8.99809 (rank : 361)	NC score	0.019469 (rank : 345)
Query Neighborhood Hits	370	Target Neighborhood Hits	573	Shared Neighborhood Hits	30
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NU214_HUMAN
θ value	8.99809 (rank : 362)	NC score	0.035137 (rank : 312)
Query Neighborhood Hits	370	Target Neighborhood Hits	657	Shared Neighborhood Hits	61
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUP53_HUMAN
θ value	8.99809 (rank : 363)	NC score	0.016594 (rank : 356)
Query Neighborhood Hits	370	Target Neighborhood Hits	156	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

PELP1_HUMAN
θ value	8.99809 (rank : 364)	NC score	0.019093 (rank : 349)
Query Neighborhood Hits	370	Target Neighborhood Hits	596	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PO6F2_MOUSE
θ value	8.99809 (rank : 365)	NC score	0.019781 (rank : 344)
Query Neighborhood Hits	370	Target Neighborhood Hits	639	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PRAX_MOUSE
θ value	8.99809 (rank : 366)	NC score	0.092238 (rank : 239)
Query Neighborhood Hits	370	Target Neighborhood Hits	199	Shared Neighborhood Hits	55
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SYNJ2_HUMAN
θ value	8.99809 (rank : 367)	NC score	0.008895 (rank : 376)
Query Neighborhood Hits	370	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

UBP8_HUMAN
θ value	8.99809 (rank : 368)	NC score	0.005608 (rank : 389)
Query Neighborhood Hits	370	Target Neighborhood Hits	751	Shared Neighborhood Hits	36
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

WASIP_MOUSE
θ value	8.99809 (rank : 369)	NC score	0.034407 (rank : 313)
Query Neighborhood Hits	370	Target Neighborhood Hits	392	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WNK3_HUMAN
θ value	8.99809 (rank : 370)	NC score	0.005682 (rank : 387)
Query Neighborhood Hits	370	Target Neighborhood Hits	948	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

APBB2_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.060820 (rank : 263)
Query Neighborhood Hits	370	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

CAR11_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.059060 (rank : 268)
Query Neighborhood Hits	370	Target Neighborhood Hits	690	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CAR14_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.053011 (rank : 278)
Query Neighborhood Hits	370	Target Neighborhood Hits	449	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

EDD1_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.107760 (rank : 229)
Query Neighborhood Hits	370	Target Neighborhood Hits	170	Shared Neighborhood Hits	22
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.107557 (rank : 230)
Query Neighborhood Hits	370	Target Neighborhood Hits	167	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HECD1_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.092629 (rank : 238)
Query Neighborhood Hits	370	Target Neighborhood Hits	371	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HECD2_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.152720 (rank : 217)
Query Neighborhood Hits	370	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.153735 (rank : 216)
Query Neighborhood Hits	370	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD3_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.104991 (rank : 233)
Query Neighborhood Hits	370	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.106918 (rank : 231)
Query Neighborhood Hits	370	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC2_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.099278 (rank : 237)
Query Neighborhood Hits	370	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.100462 (rank : 236)
Query Neighborhood Hits	370	Target Neighborhood Hits	167	Shared Neighborhood Hits	23
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC3_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.123366 (rank : 226)
Query Neighborhood Hits	370	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.126932 (rank : 225)
Query Neighborhood Hits	370	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HTRA3_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.058535 (rank : 270)
Query Neighborhood Hits	370	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.064084 (rank : 260)
Query Neighborhood Hits	370	Target Neighborhood Hits	156	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HUWE1_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.159668 (rank : 215)
Query Neighborhood Hits	370	Target Neighborhood Hits	443	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.161880 (rank : 212)
Query Neighborhood Hits	370	Target Neighborhood Hits	406	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

K0317_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.161149 (rank : 213)
Query Neighborhood Hits	370	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.161080 (rank : 214)
Query Neighborhood Hits	370	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

LMO7_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.078522 (rank : 247)
Query Neighborhood Hits	370	Target Neighborhood Hits	507	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PDZD8_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.088848 (rank : 240)
Query Neighborhood Hits	370	Target Neighborhood Hits	185	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PRAX_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.066639 (rank : 258)
Query Neighborhood Hits	370	Target Neighborhood Hits	215	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRP40_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.070180 (rank : 255)
Query Neighborhood Hits	370	Target Neighborhood Hits	442	Shared Neighborhood Hits	51
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.069187 (rank : 256)
Query Neighborhood Hits	370	Target Neighborhood Hits	447	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PTN23_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.050163 (rank : 280)
Query Neighborhood Hits	370	Target Neighborhood Hits	646	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RAIN_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.055879 (rank : 275)
Query Neighborhood Hits	370	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RAIN_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.055151 (rank : 276)
Query Neighborhood Hits	370	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U0S6, Q6GQW4	Gene names	Rasip1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RHPN2_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.082705 (rank : 243)
Query Neighborhood Hits	370	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RNF41_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.059959 (rank : 265)
Query Neighborhood Hits	370	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.059845 (rank : 266)
Query Neighborhood Hits	370	Target Neighborhood Hits	224	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SRRM1_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.058618 (rank : 269)
Query Neighborhood Hits	370	Target Neighborhood Hits	966	Shared Neighborhood Hits	95
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.062502 (rank : 261)
Query Neighborhood Hits	370	Target Neighborhood Hits	1470	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARA_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.057152 (rank : 272)
Query Neighborhood Hits	370	Target Neighborhood Hits	1626	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TIAM1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.075583 (rank : 252)
Query Neighborhood Hits	370	Target Neighborhood Hits	225	Shared Neighborhood Hits	70
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.050758 (rank : 279)
Query Neighborhood Hits	370	Target Neighborhood Hits	205	Shared Neighborhood Hits	53
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TRIPC_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.145178 (rank : 222)
Query Neighborhood Hits	370	Target Neighborhood Hits	319	Shared Neighborhood Hits	34
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

UBE3A_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.148919 (rank : 218)
Query Neighborhood Hits	370	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.146958 (rank : 220)
Query Neighborhood Hits	370	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.147179 (rank : 219)
Query Neighborhood Hits	370	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.146923 (rank : 221)
Query Neighborhood Hits	370	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

WWC3_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.079848 (rank : 245)
Query Neighborhood Hits	370	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

Hits sorted by NC score

MAGI2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	370	Target Neighborhood Hits	370	Shared Neighborhood Hits	370
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
NC score	0.987701 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	370	Target Neighborhood Hits	373	Shared Neighborhood Hits	288
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI1_HUMAN
NC score	0.958995 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	370	Target Neighborhood Hits	388	Shared Neighborhood Hits	240
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.956035 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	370	Target Neighborhood Hits	403	Shared Neighborhood Hits	241
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MPDZ_HUMAN
NC score	0.703165 (rank : 5)	θ value	8.36355e-22 (rank : 5)
Query Neighborhood Hits	370	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
NC score	0.696125 (rank : 6)	θ value	2.27762e-19 (rank : 7)
Query Neighborhood Hits	370	Target Neighborhood Hits	298	Shared Neighborhood Hits	196
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

INADL_MOUSE
NC score	0.696021 (rank : 7)	θ value	4.29542e-18 (rank : 8)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	197
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

SYJ2B_HUMAN
NC score	0.694528 (rank : 8)	θ value	2.36244e-08 (rank : 67)
Query Neighborhood Hits	370	Target Neighborhood Hits	162	Shared Neighborhood Hits	159
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

INADL_HUMAN
NC score	0.691367 (rank : 9)	θ value	1.058e-16 (rank : 10)
Query Neighborhood Hits	370	Target Neighborhood Hits	260	Shared Neighborhood Hits	193
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

LIN7B_HUMAN
NC score	0.690439 (rank : 10)	θ value	2.52405e-10 (rank : 49)
Query Neighborhood Hits	370	Target Neighborhood Hits	200	Shared Neighborhood Hits	188
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.689759 (rank : 11)	θ value	6.64225e-11 (rank : 39)
Query Neighborhood Hits	370	Target Neighborhood Hits	200	Shared Neighborhood Hits	188
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7C_HUMAN
NC score	0.689268 (rank : 12)	θ value	1.47974e-10 (rank : 47)
Query Neighborhood Hits	370	Target Neighborhood Hits	198	Shared Neighborhood Hits	188
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.689268 (rank : 13)	θ value	1.47974e-10 (rank : 48)
Query Neighborhood Hits	370	Target Neighborhood Hits	198	Shared Neighborhood Hits	188
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7A_MOUSE
NC score	0.683789 (rank : 14)	θ value	9.59137e-10 (rank : 54)
Query Neighborhood Hits	370	Target Neighborhood Hits	193	Shared Neighborhood Hits	187
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7A_HUMAN
NC score	0.683680 (rank : 15)	θ value	9.59137e-10 (rank : 53)
Query Neighborhood Hits	370	Target Neighborhood Hits	193	Shared Neighborhood Hits	187
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

PDZD7_HUMAN
NC score	0.671819 (rank : 16)	θ value	8.11959e-09 (rank : 62)
Query Neighborhood Hits	370	Target Neighborhood Hits	181	Shared Neighborhood Hits	170
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PARD3_MOUSE
NC score	0.643239 (rank : 17)	θ value	2.88119e-14 (rank : 17)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	164
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PARD3_HUMAN
NC score	0.641785 (rank : 18)	θ value	7.58209e-15 (rank : 13)
Query Neighborhood Hits	370	Target Neighborhood Hits	312	Shared Neighborhood Hits	166
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

GRIP2_HUMAN
NC score	0.637427 (rank : 19)	θ value	6.64225e-11 (rank : 38)
Query Neighborhood Hits	370	Target Neighborhood Hits	256	Shared Neighborhood Hits	193
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

USH1C_HUMAN
NC score	0.636021 (rank : 20)	θ value	7.59969e-07 (rank : 84)
Query Neighborhood Hits	370	Target Neighborhood Hits	327	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

WHRN_MOUSE
NC score	0.632717 (rank : 21)	θ value	2.36244e-08 (rank : 68)
Query Neighborhood Hits	370	Target Neighborhood Hits	412	Shared Neighborhood Hits	209
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PAR3L_HUMAN
NC score	0.631560 (rank : 22)	θ value	1.133e-10 (rank : 46)
Query Neighborhood Hits	370	Target Neighborhood Hits	297	Shared Neighborhood Hits	166
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

WHRN_HUMAN
NC score	0.630325 (rank : 23)	θ value	8.11959e-09 (rank : 63)
Query Neighborhood Hits	370	Target Neighborhood Hits	325	Shared Neighborhood Hits	197
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

GRIP1_HUMAN
NC score	0.629057 (rank : 24)	θ value	1.17247e-07 (rank : 74)
Query Neighborhood Hits	370	Target Neighborhood Hits	231	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
NC score	0.624192 (rank : 25)	θ value	2.36244e-08 (rank : 66)
Query Neighborhood Hits	370	Target Neighborhood Hits	241	Shared Neighborhood Hits	193
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PDZD1_MOUSE
NC score	0.623261 (rank : 26)	θ value	1.99992e-07 (rank : 78)
Query Neighborhood Hits	370	Target Neighborhood Hits	191	Shared Neighborhood Hits	157
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

DLG4_MOUSE
NC score	0.621489 (rank : 27)	θ value	7.84624e-12 (rank : 29)
Query Neighborhood Hits	370	Target Neighborhood Hits	282	Shared Neighborhood Hits	187
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.620541 (rank : 28)	θ value	7.84624e-12 (rank : 28)
Query Neighborhood Hits	370	Target Neighborhood Hits	286	Shared Neighborhood Hits	185
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG3_MOUSE
NC score	0.616207 (rank : 29)	θ value	2.20605e-14 (rank : 16)
Query Neighborhood Hits	370	Target Neighborhood Hits	274	Shared Neighborhood Hits	182
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.614661 (rank : 30)	θ value	1.68911e-14 (rank : 15)
Query Neighborhood Hits	370	Target Neighborhood Hits	269	Shared Neighborhood Hits	182
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

PDZD2_HUMAN
NC score	0.610405 (rank : 31)	θ value	2.98157e-11 (rank : 36)
Query Neighborhood Hits	370	Target Neighborhood Hits	772	Shared Neighborhood Hits	221
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PDZD1_HUMAN
NC score	0.610287 (rank : 32)	θ value	4.30538e-10 (rank : 52)
Query Neighborhood Hits	370	Target Neighborhood Hits	190	Shared Neighborhood Hits	154
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZ11_HUMAN
NC score	0.609135 (rank : 33)	θ value	6.43352e-06 (rank : 103)
Query Neighborhood Hits	370	Target Neighborhood Hits	160	Shared Neighborhood Hits	146
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

DLG2_HUMAN
NC score	0.608752 (rank : 34)	θ value	1.68911e-14 (rank : 14)
Query Neighborhood Hits	370	Target Neighborhood Hits	279	Shared Neighborhood Hits	182
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

NHRF2_HUMAN
NC score	0.608263 (rank : 35)	θ value	1.25267e-09 (rank : 55)
Query Neighborhood Hits	370	Target Neighborhood Hits	197	Shared Neighborhood Hits	166
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

DLG1_HUMAN
NC score	0.606659 (rank : 36)	θ value	4.16044e-13 (rank : 22)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	180
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG2_MOUSE
NC score	0.605770 (rank : 37)	θ value	7.84624e-12 (rank : 27)
Query Neighborhood Hits	370	Target Neighborhood Hits	271	Shared Neighborhood Hits	181
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG1_MOUSE
NC score	0.605369 (rank : 38)	θ value	1.42992e-13 (rank : 19)
Query Neighborhood Hits	370	Target Neighborhood Hits	285	Shared Neighborhood Hits	180
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

PDZ11_MOUSE
NC score	0.604555 (rank : 39)	θ value	3.19293e-05 (rank : 118)
Query Neighborhood Hits	370	Target Neighborhood Hits	154	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

NHERF_MOUSE
NC score	0.600074 (rank : 40)	θ value	4.92598e-06 (rank : 100)
Query Neighborhood Hits	370	Target Neighborhood Hits	195	Shared Neighborhood Hits	162
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_MOUSE
NC score	0.599478 (rank : 41)	θ value	1.25267e-09 (rank : 56)
Query Neighborhood Hits	370	Target Neighborhood Hits	194	Shared Neighborhood Hits	167
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

LNX2_MOUSE
NC score	0.594529 (rank : 42)	θ value	2.52405e-10 (rank : 51)
Query Neighborhood Hits	370	Target Neighborhood Hits	407	Shared Neighborhood Hits	183
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX2_HUMAN
NC score	0.594357 (rank : 43)	θ value	1.02475e-11 (rank : 32)
Query Neighborhood Hits	370	Target Neighborhood Hits	389	Shared Neighborhood Hits	180
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

USH1C_MOUSE
NC score	0.591744 (rank : 44)	θ value	1.09739e-05 (rank : 111)
Query Neighborhood Hits	370	Target Neighborhood Hits	557	Shared Neighborhood Hits	209
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

GOPC_MOUSE
NC score	0.591253 (rank : 45)	θ value	1.09739e-05 (rank : 108)
Query Neighborhood Hits	370	Target Neighborhood Hits	323	Shared Neighborhood Hits	174
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

IL16_HUMAN
NC score	0.588560 (rank : 46)	θ value	6.43352e-06 (rank : 102)
Query Neighborhood Hits	370	Target Neighborhood Hits	207	Shared Neighborhood Hits	148
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LNX1_HUMAN
NC score	0.587627 (rank : 47)	θ value	2.52405e-10 (rank : 50)
Query Neighborhood Hits	370	Target Neighborhood Hits	379	Shared Neighborhood Hits	174
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
NC score	0.585948 (rank : 48)	θ value	6.21693e-09 (rank : 61)
Query Neighborhood Hits	370	Target Neighborhood Hits	377	Shared Neighborhood Hits	181
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

NHERF_HUMAN
NC score	0.583513 (rank : 49)	θ value	2.21117e-06 (rank : 95)
Query Neighborhood Hits	370	Target Neighborhood Hits	190	Shared Neighborhood Hits	158
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

GOPC_HUMAN
NC score	0.582152 (rank : 50)	θ value	1.09739e-05 (rank : 107)
Query Neighborhood Hits	370	Target Neighborhood Hits	377	Shared Neighborhood Hits	175
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SNTG2_HUMAN
NC score	0.580559 (rank : 51)	θ value	7.59969e-07 (rank : 83)
Query Neighborhood Hits	370	Target Neighborhood Hits	191	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

ZO3_MOUSE
NC score	0.568302 (rank : 52)	θ value	1.74796e-11 (rank : 35)
Query Neighborhood Hits	370	Target Neighborhood Hits	224	Shared Neighborhood Hits	179
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_HUMAN
NC score	0.562197 (rank : 53)	θ value	2.69671e-12 (rank : 26)
Query Neighborhood Hits	370	Target Neighborhood Hits	219	Shared Neighborhood Hits	174
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PDZD3_HUMAN
NC score	0.558275 (rank : 54)	θ value	1.29631e-06 (rank : 89)
Query Neighborhood Hits	370	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

SNTG1_HUMAN
NC score	0.556429 (rank : 55)	θ value	9.92553e-07 (rank : 86)
Query Neighborhood Hits	370	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

TX1B3_HUMAN
NC score	0.555829 (rank : 56)	θ value	0.00509761 (rank : 172)
Query Neighborhood Hits	370	Target Neighborhood Hits	161	Shared Neighborhood Hits	153
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

IL16_MOUSE
NC score	0.555589 (rank : 57)	θ value	0.00035302 (rank : 148)
Query Neighborhood Hits	370	Target Neighborhood Hits	189	Shared Neighborhood Hits	143
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTG1_MOUSE
NC score	0.555136 (rank : 58)	θ value	1.29631e-06 (rank : 91)
Query Neighborhood Hits	370	Target Neighborhood Hits	179	Shared Neighborhood Hits	173
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTB2_HUMAN
NC score	0.553240 (rank : 59)	θ value	1.17247e-07 (rank : 75)
Query Neighborhood Hits	370	Target Neighborhood Hits	180	Shared Neighborhood Hits	164
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
NC score	0.552566 (rank : 60)	θ value	1.53129e-07 (rank : 77)
Query Neighborhood Hits	370	Target Neighborhood Hits	181	Shared Neighborhood Hits	163
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

TX1B3_MOUSE
NC score	0.552114 (rank : 61)	θ value	0.00509761 (rank : 173)
Query Neighborhood Hits	370	Target Neighborhood Hits	158	Shared Neighborhood Hits	150
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

SNTG2_MOUSE
NC score	0.549585 (rank : 62)	θ value	1.99992e-07 (rank : 79)
Query Neighborhood Hits	370	Target Neighborhood Hits	176	Shared Neighborhood Hits	171
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTA1_HUMAN
NC score	0.549039 (rank : 63)	θ value	2.61198e-07 (rank : 80)
Query Neighborhood Hits	370	Target Neighborhood Hits	186	Shared Neighborhood Hits	171
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
NC score	0.540469 (rank : 64)	θ value	4.45536e-07 (rank : 82)
Query Neighborhood Hits	370	Target Neighborhood Hits	170	Shared Neighborhood Hits	164
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PDZD3_MOUSE
NC score	0.529461 (rank : 65)	θ value	0.000121331 (rank : 136)
Query Neighborhood Hits	370	Target Neighborhood Hits	171	Shared Neighborhood Hits	156
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

K1849_HUMAN
NC score	0.520518 (rank : 66)	θ value	8.67504e-11 (rank : 42)
Query Neighborhood Hits	370	Target Neighborhood Hits	220	Shared Neighborhood Hits	147
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SNTB1_HUMAN
NC score	0.515069 (rank : 67)	θ value	3.77169e-06 (rank : 99)
Query Neighborhood Hits	370	Target Neighborhood Hits	157	Shared Neighborhood Hits	152
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.511511 (rank : 68)	θ value	1.09739e-05 (rank : 110)
Query Neighborhood Hits	370	Target Neighborhood Hits	160	Shared Neighborhood Hits	150
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PZRN4_HUMAN
NC score	0.511227 (rank : 69)	θ value	5.43371e-13 (rank : 23)
Query Neighborhood Hits	370	Target Neighborhood Hits	438	Shared Neighborhood Hits	156
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZO1_MOUSE
NC score	0.510324 (rank : 70)	θ value	4.0297e-08 (rank : 71)
Query Neighborhood Hits	370	Target Neighborhood Hits	453	Shared Neighborhood Hits	189
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_HUMAN
NC score	0.507013 (rank : 71)	θ value	1.06045e-08 (rank : 64)
Query Neighborhood Hits	370	Target Neighborhood Hits	474	Shared Neighborhood Hits	197
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

K1849_MOUSE
NC score	0.501533 (rank : 72)	θ value	1.33837e-11 (rank : 34)
Query Neighborhood Hits	370	Target Neighborhood Hits	335	Shared Neighborhood Hits	157
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZO2_HUMAN
NC score	0.488538 (rank : 73)	θ value	9.29e-05 (rank : 133)
Query Neighborhood Hits	370	Target Neighborhood Hits	289	Shared Neighborhood Hits	180
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
NC score	0.484734 (rank : 74)	θ value	9.29e-05 (rank : 134)
Query Neighborhood Hits	370	Target Neighborhood Hits	296	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PZRN3_MOUSE
NC score	0.483189 (rank : 75)	θ value	3.41135e-07 (rank : 81)
Query Neighborhood Hits	370	Target Neighborhood Hits	447	Shared Neighborhood Hits	157
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.480978 (rank : 76)	θ value	1.29631e-06 (rank : 90)
Query Neighborhood Hits	370	Target Neighborhood Hits	461	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SAV1_MOUSE
NC score	0.469224 (rank : 77)	θ value	1.09485e-13 (rank : 18)
Query Neighborhood Hits	370	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SAV1_HUMAN
NC score	0.469066 (rank : 78)	θ value	2.43908e-13 (rank : 20)
Query Neighborhood Hits	370	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

PDLI2_HUMAN
NC score	0.464523 (rank : 79)	θ value	1.53129e-07 (rank : 76)
Query Neighborhood Hits	370	Target Neighborhood Hits	245	Shared Neighborhood Hits	131
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI2_MOUSE
NC score	0.442610 (rank : 80)	θ value	3.77169e-06 (rank : 97)
Query Neighborhood Hits	370	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

APBA3_HUMAN
NC score	0.428503 (rank : 81)	θ value	2.88788e-06 (rank : 96)
Query Neighborhood Hits	370	Target Neighborhood Hits	201	Shared Neighborhood Hits	141
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

LAP4_HUMAN
NC score	0.427712 (rank : 82)	θ value	2.79066e-09 (rank : 59)
Query Neighborhood Hits	370	Target Neighborhood Hits	608	Shared Neighborhood Hits	202
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

YAP1_MOUSE
NC score	0.425078 (rank : 83)	θ value	8.67504e-11 (rank : 45)
Query Neighborhood Hits	370	Target Neighborhood Hits	96	Shared Neighborhood Hits	56
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

STXB4_HUMAN
NC score	0.423484 (rank : 84)	θ value	1.43324e-05 (rank : 113)
Query Neighborhood Hits	370	Target Neighborhood Hits	616	Shared Neighborhood Hits	141
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

APBA3_MOUSE
NC score	0.423130 (rank : 85)	θ value	1.17247e-07 (rank : 73)
Query Neighborhood Hits	370	Target Neighborhood Hits	174	Shared Neighborhood Hits	134
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA1_HUMAN
NC score	0.421086 (rank : 86)	θ value	2.44474e-05 (rank : 117)
Query Neighborhood Hits	370	Target Neighborhood Hits	325	Shared Neighborhood Hits	154
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

LAP4_MOUSE
NC score	0.420644 (rank : 87)	θ value	1.38499e-08 (rank : 65)
Query Neighborhood Hits	370	Target Neighborhood Hits	590	Shared Neighborhood Hits	201
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

STXB4_MOUSE
NC score	0.418260 (rank : 88)	θ value	5.44631e-05 (rank : 124)
Query Neighborhood Hits	370	Target Neighborhood Hits	629	Shared Neighborhood Hits	139
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

MPP4_HUMAN
NC score	0.413156 (rank : 89)	θ value	0.0193708 (rank : 191)
Query Neighborhood Hits	370	Target Neighborhood Hits	205	Shared Neighborhood Hits	142
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PTN13_HUMAN
NC score	0.412979 (rank : 90)	θ value	3.51386e-20 (rank : 6)
Query Neighborhood Hits	370	Target Neighborhood Hits	471	Shared Neighborhood Hits	195
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PICK1_MOUSE
NC score	0.410919 (rank : 91)	θ value	4.1701e-05 (rank : 120)
Query Neighborhood Hits	370	Target Neighborhood Hits	131	Shared Neighborhood Hits	122
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

GRASP_HUMAN
NC score	0.409976 (rank : 92)	θ value	0.0193708 (rank : 190)
Query Neighborhood Hits	370	Target Neighborhood Hits	147	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.409596 (rank : 93)	θ value	0.0252991 (rank : 195)
Query Neighborhood Hits	370	Target Neighborhood Hits	131	Shared Neighborhood Hits	117
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PICK1_HUMAN
NC score	0.409510 (rank : 94)	θ value	5.44631e-05 (rank : 123)
Query Neighborhood Hits	370	Target Neighborhood Hits	132	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

MPP3_MOUSE
NC score	0.407861 (rank : 95)	θ value	9.29e-05 (rank : 130)
Query Neighborhood Hits	370	Target Neighborhood Hits	165	Shared Neighborhood Hits	134
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

WWC1_HUMAN
NC score	0.407235 (rank : 96)	θ value	1.058e-16 (rank : 11)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

PSCBP_MOUSE
NC score	0.405708 (rank : 97)	θ value	0.000786445 (rank : 157)
Query Neighborhood Hits	370	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

WWC1_MOUSE
NC score	0.405022 (rank : 98)	θ value	1.058e-16 (rank : 12)
Query Neighborhood Hits	370	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

MPP5_HUMAN
NC score	0.403320 (rank : 99)	θ value	0.00134147 (rank : 162)
Query Neighborhood Hits	370	Target Neighborhood Hits	231	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

SYP2L_HUMAN
NC score	0.403236 (rank : 100)	θ value	1.43324e-05 (rank : 114)
Query Neighborhood Hits	370	Target Neighborhood Hits	400	Shared Neighborhood Hits	143
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PTN13_MOUSE
NC score	0.402662 (rank : 101)	θ value	6.20254e-17 (rank : 9)
Query Neighborhood Hits	370	Target Neighborhood Hits	426	Shared Neighborhood Hits	197
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

MPP3_HUMAN
NC score	0.402384 (rank : 102)	θ value	0.00035302 (rank : 149)
Query Neighborhood Hits	370	Target Neighborhood Hits	171	Shared Neighborhood Hits	134
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

APBA2_HUMAN
NC score	0.402218 (rank : 103)	θ value	0.000270298 (rank : 143)
Query Neighborhood Hits	370	Target Neighborhood Hits	220	Shared Neighborhood Hits	148
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

MPP5_MOUSE
NC score	0.401752 (rank : 104)	θ value	0.00175202 (rank : 165)
Query Neighborhood Hits	370	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

APBA2_MOUSE
NC score	0.401469 (rank : 105)	θ value	0.000270298 (rank : 144)
Query Neighborhood Hits	370	Target Neighborhood Hits	219	Shared Neighborhood Hits	148
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

AFAD_HUMAN
NC score	0.400181 (rank : 106)	θ value	0.0113563 (rank : 180)
Query Neighborhood Hits	370	Target Neighborhood Hits	689	Shared Neighborhood Hits	154
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

NEB1_HUMAN
NC score	0.391825 (rank : 107)	θ value	1.69304e-06 (rank : 94)
Query Neighborhood Hits	370	Target Neighborhood Hits	829	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PSCBP_HUMAN
NC score	0.391327 (rank : 108)	θ value	0.000602161 (rank : 155)
Query Neighborhood Hits	370	Target Neighborhood Hits	123	Shared Neighborhood Hits	114
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

MPP4_MOUSE
NC score	0.377739 (rank : 109)	θ value	0.125558 (rank : 220)
Query Neighborhood Hits	370	Target Neighborhood Hits	188	Shared Neighborhood Hits	123
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

EM55_HUMAN
NC score	0.376296 (rank : 110)	θ value	0.000786445 (rank : 156)
Query Neighborhood Hits	370	Target Neighborhood Hits	228	Shared Neighborhood Hits	130
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

SYNP2_MOUSE
NC score	0.373625 (rank : 111)	θ value	4.92598e-06 (rank : 101)
Query Neighborhood Hits	370	Target Neighborhood Hits	252	Shared Neighborhood Hits	129
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

EM55_MOUSE
NC score	0.371897 (rank : 112)	θ value	0.00102713 (rank : 159)
Query Neighborhood Hits	370	Target Neighborhood Hits	221	Shared Neighborhood Hits	128
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NEB2_HUMAN
NC score	0.367711 (rank : 113)	θ value	1.29631e-06 (rank : 87)
Query Neighborhood Hits	370	Target Neighborhood Hits	883	Shared Neighborhood Hits	143
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDZK4_HUMAN
NC score	0.365945 (rank : 114)	θ value	0.0113563 (rank : 183)
Query Neighborhood Hits	370	Target Neighborhood Hits	165	Shared Neighborhood Hits	116
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

NEB2_MOUSE
NC score	0.364592 (rank : 115)	θ value	1.29631e-06 (rank : 88)
Query Neighborhood Hits	370	Target Neighborhood Hits	889	Shared Neighborhood Hits	145
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDZK4_MOUSE
NC score	0.363253 (rank : 116)	θ value	0.00390308 (rank : 169)
Query Neighborhood Hits	370	Target Neighborhood Hits	165	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

DLG5_HUMAN
NC score	0.362780 (rank : 117)	θ value	0.0113563 (rank : 181)
Query Neighborhood Hits	370	Target Neighborhood Hits	1088	Shared Neighborhood Hits	203
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

RHPN1_MOUSE
NC score	0.360307 (rank : 118)	θ value	0.00102713 (rank : 160)
Query Neighborhood Hits	370	Target Neighborhood Hits	154	Shared Neighborhood Hits	132
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

DVL3_HUMAN
NC score	0.344708 (rank : 119)	θ value	0.0193708 (rank : 187)
Query Neighborhood Hits	370	Target Neighborhood Hits	194	Shared Neighborhood Hits	121
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
NC score	0.344619 (rank : 120)	θ value	0.0193708 (rank : 188)
Query Neighborhood Hits	370	Target Neighborhood Hits	198	Shared Neighborhood Hits	120
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

PAR6G_MOUSE
NC score	0.342949 (rank : 121)	θ value	0.00390308 (rank : 168)
Query Neighborhood Hits	370	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

DVL1_HUMAN
NC score	0.342550 (rank : 122)	θ value	0.0330416 (rank : 197)
Query Neighborhood Hits	370	Target Neighborhood Hits	158	Shared Neighborhood Hits	119
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
NC score	0.339718 (rank : 123)	θ value	0.0252991 (rank : 194)
Query Neighborhood Hits	370	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

SYP2L_MOUSE
NC score	0.338864 (rank : 124)	θ value	1.87187e-05 (rank : 116)
Query Neighborhood Hits	370	Target Neighborhood Hits	289	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYNP2_HUMAN
NC score	0.336808 (rank : 125)	θ value	1.29631e-06 (rank : 92)
Query Neighborhood Hits	370	Target Neighborhood Hits	323	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SHAN2_HUMAN
NC score	0.336044 (rank : 126)	θ value	0.000121331 (rank : 137)
Query Neighborhood Hits	370	Target Neighborhood Hits	346	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

APXL_HUMAN
NC score	0.335535 (rank : 127)	θ value	0.00020696 (rank : 141)
Query Neighborhood Hits	370	Target Neighborhood Hits	553	Shared Neighborhood Hits	120
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

RPGF6_HUMAN
NC score	0.335325 (rank : 128)	θ value	0.00869519 (rank : 179)
Query Neighborhood Hits	370	Target Neighborhood Hits	266	Shared Neighborhood Hits	154
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PAR6G_HUMAN
NC score	0.333086 (rank : 129)	θ value	0.0431538 (rank : 205)
Query Neighborhood Hits	370	Target Neighborhood Hits	159	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

MPP6_MOUSE
NC score	0.331338 (rank : 130)	θ value	0.00134147 (rank : 163)
Query Neighborhood Hits	370	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

DVL1L_HUMAN
NC score	0.330263 (rank : 131)	θ value	0.0193708 (rank : 186)
Query Neighborhood Hits	370	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

PDLI3_HUMAN
NC score	0.329823 (rank : 132)	θ value	0.00020696 (rank : 142)
Query Neighborhood Hits	370	Target Neighborhood Hits	199	Shared Neighborhood Hits	110
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

WWP2_HUMAN
NC score	0.329602 (rank : 133)	θ value	9.26847e-13 (rank : 24)
Query Neighborhood Hits	370	Target Neighborhood Hits	177	Shared Neighborhood Hits	56
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

PAR6B_HUMAN
NC score	0.329036 (rank : 134)	θ value	0.62314 (rank : 242)
Query Neighborhood Hits	370	Target Neighborhood Hits	126	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

WWP2_MOUSE
NC score	0.329031 (rank : 135)	θ value	3.18553e-13 (rank : 21)
Query Neighborhood Hits	370	Target Neighborhood Hits	118	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

YAP1_HUMAN
NC score	0.328476 (rank : 136)	θ value	1.09739e-05 (rank : 112)
Query Neighborhood Hits	370	Target Neighborhood Hits	173	Shared Neighborhood Hits	66
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PAR6B_MOUSE
NC score	0.327820 (rank : 137)	θ value	0.62314 (rank : 243)
Query Neighborhood Hits	370	Target Neighborhood Hits	128	Shared Neighborhood Hits	121
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

ARHGB_HUMAN
NC score	0.327364 (rank : 138)	θ value	1.69304e-06 (rank : 93)
Query Neighborhood Hits	370	Target Neighborhood Hits	375	Shared Neighborhood Hits	160
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

MPP2_MOUSE
NC score	0.326842 (rank : 139)	θ value	0.00509761 (rank : 170)
Query Neighborhood Hits	370	Target Neighborhood Hits	189	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP6_HUMAN
NC score	0.326228 (rank : 140)	θ value	0.00298849 (rank : 166)
Query Neighborhood Hits	370	Target Neighborhood Hits	180	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

WWP1_MOUSE
NC score	0.325348 (rank : 141)	θ value	2.0648e-12 (rank : 25)
Query Neighborhood Hits	370	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

MPP2_HUMAN
NC score	0.323800 (rank : 142)	θ value	0.00390308 (rank : 167)
Query Neighborhood Hits	370	Target Neighborhood Hits	173	Shared Neighborhood Hits	96
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

DVL2_HUMAN
NC score	0.323490 (rank : 143)	θ value	0.0736092 (rank : 211)
Query Neighborhood Hits	370	Target Neighborhood Hits	223	Shared Neighborhood Hits	121
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.321878 (rank : 144)	θ value	0.0736092 (rank : 212)
Query Neighborhood Hits	370	Target Neighborhood Hits	233	Shared Neighborhood Hits	120
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

WWP1_HUMAN
NC score	0.321779 (rank : 145)	θ value	1.02475e-11 (rank : 33)
Query Neighborhood Hits	370	Target Neighborhood Hits	262	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ITCH_MOUSE
NC score	0.321712 (rank : 146)	θ value	5.08577e-11 (rank : 37)
Query Neighborhood Hits	370	Target Neighborhood Hits	127	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

PAR6A_MOUSE
NC score	0.321556 (rank : 147)	θ value	0.0736092 (rank : 213)
Query Neighborhood Hits	370	Target Neighborhood Hits	115	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

SDCB1_MOUSE
NC score	0.321364 (rank : 148)	θ value	0.47712 (rank : 237)
Query Neighborhood Hits	370	Target Neighborhood Hits	144	Shared Neighborhood Hits	134
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

PDLI1_MOUSE
NC score	0.320408 (rank : 149)	θ value	0.00869519 (rank : 178)
Query Neighborhood Hits	370	Target Neighborhood Hits	213	Shared Neighborhood Hits	107
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

ITCH_HUMAN
NC score	0.319846 (rank : 150)	θ value	8.67504e-11 (rank : 41)
Query Neighborhood Hits	370	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

PAR6A_HUMAN
NC score	0.317879 (rank : 151)	θ value	0.21417 (rank : 225)
Query Neighborhood Hits	370	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

RHPN1_HUMAN
NC score	0.317356 (rank : 152)	θ value	0.0330416 (rank : 202)
Query Neighborhood Hits	370	Target Neighborhood Hits	158	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PDLI4_HUMAN
NC score	0.317346 (rank : 153)	θ value	0.00665767 (rank : 174)
Query Neighborhood Hits	370	Target Neighborhood Hits	245	Shared Neighborhood Hits	113
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
NC score	0.316458 (rank : 154)	θ value	0.0113563 (rank : 182)
Query Neighborhood Hits	370	Target Neighborhood Hits	233	Shared Neighborhood Hits	115
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

WWTR1_MOUSE
NC score	0.313962 (rank : 155)	θ value	9.29e-05 (rank : 132)
Query Neighborhood Hits	370	Target Neighborhood Hits	54	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

PDLI1_HUMAN
NC score	0.313841 (rank : 156)	θ value	0.00869519 (rank : 177)
Query Neighborhood Hits	370	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

WWTR1_HUMAN
NC score	0.312472 (rank : 157)	θ value	5.44631e-05 (rank : 125)
Query Neighborhood Hits	370	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

SDCB1_HUMAN
NC score	0.309761 (rank : 158)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	370	Target Neighborhood Hits	150	Shared Neighborhood Hits	140
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SMUF2_HUMAN
NC score	0.305239 (rank : 159)	θ value	2.13673e-09 (rank : 58)
Query Neighborhood Hits	370	Target Neighborhood Hits	142	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

PDLI3_MOUSE
NC score	0.304886 (rank : 160)	θ value	0.0193708 (rank : 192)
Query Neighborhood Hits	370	Target Neighborhood Hits	197	Shared Neighborhood Hits	106
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SHAN2_MOUSE
NC score	0.303447 (rank : 161)	θ value	0.000158464 (rank : 140)
Query Neighborhood Hits	370	Target Neighborhood Hits	446	Shared Neighborhood Hits	135
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SMUF1_MOUSE
NC score	0.303430 (rank : 162)	θ value	3.64472e-09 (rank : 60)
Query Neighborhood Hits	370	Target Neighborhood Hits	142	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

NEDD4_HUMAN
NC score	0.300823 (rank : 163)	θ value	6.64225e-11 (rank : 40)
Query Neighborhood Hits	370	Target Neighborhood Hits	214	Shared Neighborhood Hits	50
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

ARHGC_HUMAN
NC score	0.300786 (rank : 164)	θ value	5.44631e-05 (rank : 121)
Query Neighborhood Hits	370	Target Neighborhood Hits	351	Shared Neighborhood Hits	145
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

WWOX_HUMAN
NC score	0.297843 (rank : 165)	θ value	8.67504e-11 (rank : 43)
Query Neighborhood Hits	370	Target Neighborhood Hits	115	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

ARHGC_MOUSE
NC score	0.296872 (rank : 166)	θ value	9.29e-05 (rank : 129)
Query Neighborhood Hits	370	Target Neighborhood Hits	344	Shared Neighborhood Hits	149
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

WWOX_MOUSE
NC score	0.295190 (rank : 167)	θ value	8.67504e-11 (rank : 44)
Query Neighborhood Hits	370	Target Neighborhood Hits	118	Shared Neighborhood Hits	43
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

NED4L_MOUSE
NC score	0.294984 (rank : 168)	θ value	7.84624e-12 (rank : 31)
Query Neighborhood Hits	370	Target Neighborhood Hits	231	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
NC score	0.294698 (rank : 169)	θ value	7.84624e-12 (rank : 30)
Query Neighborhood Hits	370	Target Neighborhood Hits	238	Shared Neighborhood Hits	56
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_MOUSE
NC score	0.293545 (rank : 170)	θ value	2.13673e-09 (rank : 57)
Query Neighborhood Hits	370	Target Neighborhood Hits	212	Shared Neighborhood Hits	52
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

SMUF1_HUMAN
NC score	0.292258 (rank : 171)	θ value	6.87365e-08 (rank : 72)
Query Neighborhood Hits	370	Target Neighborhood Hits	135	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

RPGF2_HUMAN
NC score	0.282446 (rank : 172)	θ value	0.365318 (rank : 234)
Query Neighborhood Hits	370	Target Neighborhood Hits	242	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SDCB2_MOUSE
NC score	0.281076 (rank : 173)	θ value	0.813845 (rank : 250)
Query Neighborhood Hits	370	Target Neighborhood Hits	118	Shared Neighborhood Hits	111
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

RGS12_HUMAN
NC score	0.278789 (rank : 174)	θ value	0.0431538 (rank : 206)
Query Neighborhood Hits	370	Target Neighborhood Hits	333	Shared Neighborhood Hits	144
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

GIPC1_MOUSE
NC score	0.278264 (rank : 175)	θ value	0.00134147 (rank : 161)
Query Neighborhood Hits	370	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

BAG3_HUMAN
NC score	0.273498 (rank : 176)	θ value	7.1131e-05 (rank : 126)
Query Neighborhood Hits	370	Target Neighborhood Hits	314	Shared Neighborhood Hits	70
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

KGUA_HUMAN
NC score	0.272969 (rank : 177)	θ value	0.00869519 (rank : 175)
Query Neighborhood Hits	370	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

SDCB2_HUMAN
NC score	0.270203 (rank : 178)	θ value	1.38821 (rank : 260)
Query Neighborhood Hits	370	Target Neighborhood Hits	121	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

KGUA_MOUSE
NC score	0.270030 (rank : 179)	θ value	0.0431538 (rank : 204)
Query Neighborhood Hits	370	Target Neighborhood Hits	45	Shared Neighborhood Hits	31
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

NOS1_HUMAN
NC score	0.268580 (rank : 180)	θ value	0.0252991 (rank : 196)
Query Neighborhood Hits	370	Target Neighborhood Hits	218	Shared Neighborhood Hits	140
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

GIPC1_HUMAN
NC score	0.266636 (rank : 181)	θ value	0.00175202 (rank : 164)
Query Neighborhood Hits	370	Target Neighborhood Hits	91	Shared Neighborhood Hits	88
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

LDB3_MOUSE
NC score	0.266435 (rank : 182)	θ value	1.09739e-05 (rank : 109)
Query Neighborhood Hits	370	Target Neighborhood Hits	510	Shared Neighborhood Hits	126
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PDLI5_MOUSE
NC score	0.263603 (rank : 183)	θ value	1.87187e-05 (rank : 115)
Query Neighborhood Hits	370	Target Neighborhood Hits	287	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

LDB3_HUMAN
NC score	0.262874 (rank : 184)	θ value	7.1131e-05 (rank : 127)
Query Neighborhood Hits	370	Target Neighborhood Hits	497	Shared Neighborhood Hits	127
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PDLI5_HUMAN
NC score	0.262065 (rank : 185)	θ value	7.1131e-05 (rank : 128)
Query Neighborhood Hits	370	Target Neighborhood Hits	322	Shared Neighborhood Hits	123
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

BAG3_MOUSE
NC score	0.251460 (rank : 186)	θ value	5.44631e-05 (rank : 122)
Query Neighborhood Hits	370	Target Neighborhood Hits	513	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CNKR2_MOUSE
NC score	0.250805 (rank : 187)	θ value	3.08544e-08 (rank : 70)
Query Neighborhood Hits	370	Target Neighborhood Hits	197	Shared Neighborhood Hits	58
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.250639 (rank : 188)	θ value	3.08544e-08 (rank : 69)
Query Neighborhood Hits	370	Target Neighborhood Hits	197	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PDLI7_HUMAN
NC score	0.250537 (rank : 189)	θ value	0.000158464 (rank : 138)
Query Neighborhood Hits	370	Target Neighborhood Hits	547	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PKHA5_HUMAN
NC score	0.242901 (rank : 190)	θ value	9.92553e-07 (rank : 85)
Query Neighborhood Hits	370	Target Neighborhood Hits	455	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PDLI7_MOUSE
NC score	0.239023 (rank : 191)	θ value	0.000158464 (rank : 139)
Query Neighborhood Hits	370	Target Neighborhood Hits	279	Shared Neighborhood Hits	110
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

NOS1_MOUSE
NC score	0.234669 (rank : 192)	θ value	0.365318 (rank : 231)
Query Neighborhood Hits	370	Target Neighborhood Hits	155	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

GIPC2_HUMAN
NC score	0.228621 (rank : 193)	θ value	0.0193708 (rank : 189)
Query Neighborhood Hits	370	Target Neighborhood Hits	93	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

LRRC7_HUMAN
NC score	0.218096 (rank : 194)	θ value	0.000270298 (rank : 145)
Query Neighborhood Hits	370	Target Neighborhood Hits	423	Shared Neighborhood Hits	121
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.217149 (rank : 195)	θ value	0.000270298 (rank : 146)
Query Neighborhood Hits	370	Target Neighborhood Hits	416	Shared Neighborhood Hits	121
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

RIMS1_HUMAN
NC score	0.212715 (rank : 196)	θ value	1.81305 (rank : 266)
Query Neighborhood Hits	370	Target Neighborhood Hits	437	Shared Neighborhood Hits	144
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SHAN1_HUMAN
NC score	0.211251 (rank : 197)	θ value	3.19293e-05 (rank : 119)
Query Neighborhood Hits	370	Target Neighborhood Hits	1041	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PCLO_MOUSE
NC score	0.208420 (rank : 198)	θ value	0.000270298 (rank : 147)
Query Neighborhood Hits	370	Target Neighborhood Hits	2275	Shared Neighborhood Hits	223
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

LAP2_HUMAN
NC score	0.199025 (rank : 199)	θ value	0.000602161 (rank : 152)
Query Neighborhood Hits	370	Target Neighborhood Hits	499	Shared Neighborhood Hits	114
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PINL_HUMAN
NC score	0.198748 (rank : 200)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	370	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

RIMS2_HUMAN
NC score	0.189611 (rank : 201)	θ value	0.365318 (rank : 232)
Query Neighborhood Hits	370	Target Neighborhood Hits	342	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.189343 (rank : 202)	θ value	0.365318 (rank : 233)
Query Neighborhood Hits	370	Target Neighborhood Hits	376	Shared Neighborhood Hits	122
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

LAP2_MOUSE
NC score	0.187108 (rank : 203)	θ value	0.0330416 (rank : 200)
Query Neighborhood Hits	370	Target Neighborhood Hits	482	Shared Neighborhood Hits	115
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

GIPC3_HUMAN
NC score	0.179296 (rank : 204)	θ value	0.0563607 (rank : 207)
Query Neighborhood Hits	370	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC2_MOUSE
NC score	0.175093 (rank : 205)	θ value	0.0431538 (rank : 203)
Query Neighborhood Hits	370	Target Neighborhood Hits	71	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

PIN1_MOUSE
NC score	0.173154 (rank : 206)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	370	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

GIPC3_MOUSE
NC score	0.172688 (rank : 207)	θ value	0.0563607 (rank : 208)
Query Neighborhood Hits	370	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

PIN1_HUMAN
NC score	0.171343 (rank : 208)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	370	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PTN4_HUMAN
NC score	0.169928 (rank : 209)	θ value	3.77169e-06 (rank : 98)
Query Neighborhood Hits	370	Target Neighborhood Hits	303	Shared Neighborhood Hits	126
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.169037 (rank : 210)	θ value	9.29e-05 (rank : 131)
Query Neighborhood Hits	370	Target Neighborhood Hits	258	Shared Neighborhood Hits	118
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PDZD6_HUMAN
NC score	0.163550 (rank : 211)	θ value	0.62314 (rank : 244)
Query Neighborhood Hits	370	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

HUWE1_MOUSE
NC score	0.161880 (rank : 212)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	370	Target Neighborhood Hits	406	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

K0317_HUMAN
NC score	0.161149 (rank : 213)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	370	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.161080 (rank : 214)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	370	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

HUWE1_HUMAN
NC score	0.159668 (rank : 215)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	370	Target Neighborhood Hits	443	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HECD2_MOUSE
NC score	0.153735 (rank : 216)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	370	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_HUMAN
NC score	0.152720 (rank : 217)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	370	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_HUMAN
NC score	0.148919 (rank : 218)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	370	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3C_HUMAN
NC score	0.147179 (rank : 219)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	370	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3A_MOUSE
NC score	0.146958 (rank : 220)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	370	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_MOUSE
NC score	0.146923 (rank : 221)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	370	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

TRIPC_HUMAN
NC score	0.145178 (rank : 222)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	370	Target Neighborhood Hits	319	Shared Neighborhood Hits	34
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

CSKP_HUMAN
NC score	0.133677 (rank : 223)	θ value	8.40245e-06 (rank : 104)
Query Neighborhood Hits	370	Target Neighborhood Hits	1022	Shared Neighborhood Hits	133
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
NC score	0.130658 (rank : 224)	θ value	8.40245e-06 (rank : 105)
Query Neighborhood Hits	370	Target Neighborhood Hits	1027	Shared Neighborhood Hits	133
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

HERC5_HUMAN
NC score	0.126932 (rank : 225)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	370	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC3_HUMAN
NC score	0.123366 (rank : 226)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	370	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

CNKR1_HUMAN
NC score	0.115708 (rank : 227)	θ value	0.0193708 (rank : 185)
Query Neighborhood Hits	370	Target Neighborhood Hits	154	Shared Neighborhood Hits	20
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

RGS3_HUMAN
NC score	0.114911 (rank : 228)	θ value	0.000786445 (rank : 158)
Query Neighborhood Hits	370	Target Neighborhood Hits	1375	Shared Neighborhood Hits	139
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

EDD1_HUMAN
NC score	0.107760 (rank : 229)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	370	Target Neighborhood Hits	170	Shared Neighborhood Hits	22
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
NC score	0.107557 (rank : 230)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	370	Target Neighborhood Hits	167	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HECD3_MOUSE
NC score	0.106918 (rank : 231)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	370	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

GAS7_HUMAN
NC score	0.106757 (rank : 232)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	370	Target Neighborhood Hits	258	Shared Neighborhood Hits	44
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

HECD3_HUMAN
NC score	0.104991 (rank : 233)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	370	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

RGS3_MOUSE
NC score	0.102498 (rank : 234)	θ value	0.0330416 (rank : 201)
Query Neighborhood Hits	370	Target Neighborhood Hits	1621	Shared Neighborhood Hits	156
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

GAS7_MOUSE
NC score	0.101988 (rank : 235)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	370	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

HERC2_MOUSE
NC score	0.100462 (rank : 236)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	370	Target Neighborhood Hits	167	Shared Neighborhood Hits	23
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.099278 (rank : 237)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	370	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HECD1_HUMAN
NC score	0.092629 (rank : 238)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	370	Target Neighborhood Hits	371	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

PRAX_MOUSE
NC score	0.092238 (rank : 239)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	370	Target Neighborhood Hits	199	Shared Neighborhood Hits	55
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PDZD8_HUMAN
NC score	0.088848 (rank : 240)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	370	Target Neighborhood Hits	185	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

MAST4_HUMAN
NC score	0.083590 (rank : 241)	θ value	0.000121331 (rank : 135)
Query Neighborhood Hits	370	Target Neighborhood Hits	1804	Shared Neighborhood Hits	190
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

VCY1_HUMAN
NC score	0.083453 (rank : 242)	θ value	1.81305 (rank : 268)
Query Neighborhood Hits	370	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

RHPN2_MOUSE
NC score	0.082705 (rank : 243)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	370	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

MY18A_MOUSE
NC score	0.080106 (rank : 244)	θ value	0.00509761 (rank : 171)
Query Neighborhood Hits	370	Target Neighborhood Hits	1989	Shared Neighborhood Hits	170
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

WWC3_HUMAN
NC score	0.079848 (rank : 245)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	370	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

MAST3_HUMAN
NC score	0.079482 (rank : 246)	θ value	8.40245e-06 (rank : 106)
Query Neighborhood Hits	370	Target Neighborhood Hits	1128	Shared Neighborhood Hits	146
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

LMO7_HUMAN
NC score	0.078522 (rank : 247)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	370	Target Neighborhood Hits	507	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MAST1_MOUSE
NC score	0.078424 (rank : 248)	θ value	0.000461057 (rank : 151)
Query Neighborhood Hits	370	Target Neighborhood Hits	1123	Shared Neighborhood Hits	142
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_HUMAN
NC score	0.078231 (rank : 249)	θ value	0.000602161 (rank : 153)
Query Neighborhood Hits	370	Target Neighborhood Hits	1189	Shared Neighborhood Hits	142
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST1_HUMAN
NC score	0.077459 (rank : 250)	θ value	0.000461057 (rank : 150)
Query Neighborhood Hits	370	Target Neighborhood Hits	1146	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_MOUSE
NC score	0.076064 (rank : 251)	θ value	0.000602161 (rank : 154)
Query Neighborhood Hits	370	Target Neighborhood Hits	1110	Shared Neighborhood Hits	137
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TIAM1_HUMAN
NC score	0.075583 (rank : 252)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	370	Target Neighborhood Hits	225	Shared Neighborhood Hits	70
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SETD2_HUMAN
NC score	0.075290 (rank : 253)	θ value	0.279714 (rank : 227)
Query Neighborhood Hits	370	Target Neighborhood Hits	412	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

MY18A_HUMAN
NC score	0.070935 (rank : 254)	θ value	0.0563607 (rank : 210)
Query Neighborhood Hits	370	Target Neighborhood Hits	1929	Shared Neighborhood Hits	171
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PRP40_HUMAN
NC score	0.070180 (rank : 255)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	370	Target Neighborhood Hits	442	Shared Neighborhood Hits	51
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
NC score	0.069187 (rank : 256)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	370	Target Neighborhood Hits	447	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

SRRM2_HUMAN
NC score	0.068128 (rank : 257)	θ value	4.03905 (rank : 307)
Query Neighborhood Hits	370	Target Neighborhood Hits	1296	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PRAX_HUMAN
NC score	0.066639 (rank : 258)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	370	Target Neighborhood Hits	215	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PCLO_HUMAN
NC score	0.065979 (rank : 259)	θ value	0.21417 (rank : 226)
Query Neighborhood Hits	370	Target Neighborhood Hits	2046	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

HTRA3_MOUSE
NC score	0.064084 (rank : 260)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	370	Target Neighborhood Hits	156	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

SRRM2_MOUSE
NC score	0.062502 (rank : 261)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	370	Target Neighborhood Hits	1470	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MDC1_HUMAN
NC score	0.062337 (rank : 262)	θ value	0.163984 (rank : 222)
Query Neighborhood Hits	370	Target Neighborhood Hits	1446	Shared Neighborhood Hits	108
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

APBB2_HUMAN
NC score	0.060820 (rank : 263)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	370	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

PTN23_MOUSE
NC score	0.060086 (rank : 264)	θ value	0.0736092 (rank : 214)
Query Neighborhood Hits	370	Target Neighborhood Hits	726	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RNF41_HUMAN
NC score	0.059959 (rank : 265)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	370	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.059845 (rank : 266)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	370	Target Neighborhood Hits	224	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

CBP_MOUSE
NC score	0.059769 (rank : 267)	θ value	0.21417 (rank : 224)
Query Neighborhood Hits	370	Target Neighborhood Hits	1051	Shared Neighborhood Hits	87
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CAR11_HUMAN
NC score	0.059060 (rank : 268)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	370	Target Neighborhood Hits	690	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

SRRM1_MOUSE
NC score	0.058618 (rank : 269)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	370	Target Neighborhood Hits	966	Shared Neighborhood Hits	95
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

HTRA3_HUMAN
NC score	0.058535 (rank : 270)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	370	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HNRL1_MOUSE
NC score	0.058369 (rank : 271)	θ value	0.0330416 (rank : 199)
Query Neighborhood Hits	370	Target Neighborhood Hits	200	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

TARA_HUMAN
NC score	0.057152 (rank : 272)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	370	Target Neighborhood Hits	1626	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CBP_HUMAN
NC score	0.056620 (rank : 273)	θ value	0.47712 (rank : 235)
Query Neighborhood Hits	370	Target Neighborhood Hits	941	Shared Neighborhood Hits	86
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RHG12_MOUSE
NC score	0.056313 (rank : 274)	θ value	1.38821 (rank : 259)
Query Neighborhood Hits	370	Target Neighborhood Hits	204	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RAIN_HUMAN
NC score	0.055879 (rank : 275)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	370	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RAIN_MOUSE
NC score	0.055151 (rank : 276)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	370	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U0S6, Q6GQW4	Gene names	Rasip1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

NACAM_MOUSE
NC score	0.053385 (rank : 277)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	370	Target Neighborhood Hits	1866	Shared Neighborhood Hits	123
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CAR14_HUMAN
NC score	0.053011 (rank : 278)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	370	Target Neighborhood Hits	449	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

TIAM1_MOUSE
NC score	0.050758 (rank : 279)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	370	Target Neighborhood Hits	205	Shared Neighborhood Hits	53
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PTN23_HUMAN
NC score	0.050163 (rank : 280)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	370	Target Neighborhood Hits	646	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

HNRL1_HUMAN
NC score	0.050153 (rank : 281)	θ value	0.0330416 (rank : 198)
Query Neighborhood Hits	370	Target Neighborhood Hits	173	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

ARI1A_HUMAN
NC score	0.050117 (rank : 282)	θ value	0.0193708 (rank : 184)
Query Neighborhood Hits	370	Target Neighborhood Hits	787	Shared Neighborhood Hits	68
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

RHG12_HUMAN
NC score	0.049909 (rank : 283)	θ value	1.38821 (rank : 258)
Query Neighborhood Hits	370	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

BAT2_HUMAN
NC score	0.049821 (rank : 284)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	370	Target Neighborhood Hits	931	Shared Neighborhood Hits	90
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

AFF1_HUMAN
NC score	0.049723 (rank : 285)	θ value	0.21417 (rank : 223)
Query Neighborhood Hits	370	Target Neighborhood Hits	506	Shared Neighborhood Hits	49
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

SELPL_MOUSE
NC score	0.049132 (rank : 286)	θ value	1.81305 (rank : 267)
Query Neighborhood Hits	370	Target Neighborhood Hits	588	Shared Neighborhood Hits	64
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

TARSH_HUMAN
NC score	0.048760 (rank : 287)	θ value	0.47712 (rank : 238)
Query Neighborhood Hits	370	Target Neighborhood Hits	768	Shared Neighborhood Hits	81
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

NCOR2_HUMAN
NC score	0.048713 (rank : 288)	θ value	1.81305 (rank : 263)
Query Neighborhood Hits	370	Target Neighborhood Hits	870	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NFH_MOUSE
NC score	0.048035 (rank : 289)	θ value	0.813845 (rank : 248)
Query Neighborhood Hits	370	Target Neighborhood Hits	2247	Shared Neighborhood Hits	125
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DRP2_HUMAN
NC score	0.047675 (rank : 290)	θ value	3.0926 (rank : 277)
Query Neighborhood Hits	370	Target Neighborhood Hits	186	Shared Neighborhood Hits	26
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

NCOR2_MOUSE
NC score	0.047539 (rank : 291)	θ value	0.0961366 (rank : 218)
Query Neighborhood Hits	370	Target Neighborhood Hits	790	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

BRD4_HUMAN
NC score	0.046161 (rank : 292)	θ value	0.0252991 (rank : 193)
Query Neighborhood Hits	370	Target Neighborhood Hits	851	Shared Neighborhood Hits	73
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

HTRA1_HUMAN
NC score	0.045713 (rank : 293)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	370	Target Neighborhood Hits	155	Shared Neighborhood Hits	46
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

ABLM3_MOUSE
NC score	0.044009 (rank : 294)	θ value	3.0926 (rank : 275)
Query Neighborhood Hits	370	Target Neighborhood Hits	294	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM3_HUMAN
NC score	0.042848 (rank : 295)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	370	Target Neighborhood Hits	293	Shared Neighborhood Hits	27
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

EP300_HUMAN
NC score	0.042551 (rank : 296)	θ value	2.36792 (rank : 270)
Query Neighborhood Hits	370	Target Neighborhood Hits	821	Shared Neighborhood Hits	74
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

LIMK1_MOUSE
NC score	0.042138 (rank : 297)	θ value	0.00869519 (rank : 176)
Query Neighborhood Hits	370	Target Neighborhood Hits	1008	Shared Neighborhood Hits	92
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

CASC3_MOUSE
NC score	0.041934 (rank : 298)	θ value	0.813845 (rank : 247)
Query Neighborhood Hits	370	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CPSF6_MOUSE
NC score	0.041689 (rank : 299)	θ value	0.365318 (rank : 229)
Query Neighborhood Hits	370	Target Neighborhood Hits	356	Shared Neighborhood Hits	35
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

LIMK1_HUMAN
NC score	0.041484 (rank : 300)	θ value	0.125558 (rank : 219)
Query Neighborhood Hits	370	Target Neighborhood Hits	1005	Shared Neighborhood Hits	89
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

BRD4_MOUSE
NC score	0.041406 (rank : 301)	θ value	0.163984 (rank : 221)
Query Neighborhood Hits	370	Target Neighborhood Hits	845	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CPSF6_HUMAN
NC score	0.041246 (rank : 302)	θ value	0.365318 (rank : 228)
Query Neighborhood Hits	370	Target Neighborhood Hits	359	Shared Neighborhood Hits	34
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CIC_HUMAN
NC score	0.040846 (rank : 303)	θ value	1.06291 (rank : 251)
Query Neighborhood Hits	370	Target Neighborhood Hits	992	Shared Neighborhood Hits	86
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

WIRE_MOUSE
NC score	0.040332 (rank : 304)	θ value	5.27518 (rank : 336)
Query Neighborhood Hits	370	Target Neighborhood Hits	310	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

SAPS1_HUMAN
NC score	0.038952 (rank : 305)	θ value	0.62314 (rank : 246)
Query Neighborhood Hits	370	Target Neighborhood Hits	704	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

WIRE_HUMAN
NC score	0.038882 (rank : 306)	θ value	4.03905 (rank : 310)
Query Neighborhood Hits	370	Target Neighborhood Hits	329	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

PDC6I_MOUSE
NC score	0.038165 (rank : 307)	θ value	0.813845 (rank : 249)
Query Neighborhood Hits	370	Target Neighborhood Hits	275	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

DGCR8_MOUSE
NC score	0.037835 (rank : 308)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	370	Target Neighborhood Hits	70	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

MINT_HUMAN
NC score	0.037205 (rank : 309)	θ value	0.0961366 (rank : 217)
Query Neighborhood Hits	370	Target Neighborhood Hits	1291	Shared Neighborhood Hits	83
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DGCR8_HUMAN
NC score	0.037119 (rank : 310)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	370	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

NCOA6_MOUSE
NC score	0.035241 (rank : 311)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	370	Target Neighborhood Hits	1076	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NU214_HUMAN
NC score	0.035137 (rank : 312)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	370	Target Neighborhood Hits	657	Shared Neighborhood Hits	61
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

WASIP_MOUSE
NC score	0.034407 (rank : 313)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	370	Target Neighborhood Hits	392	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SYN1_HUMAN
NC score	0.034104 (rank : 314)	θ value	2.36792 (rank : 274)
Query Neighborhood Hits	370	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

MLL2_HUMAN
NC score	0.033305 (rank : 315)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	370	Target Neighborhood Hits	1788	Shared Neighborhood Hits	104
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

K1688_HUMAN
NC score	0.032764 (rank : 316)	θ value	0.62314 (rank : 239)
Query Neighborhood Hits	370	Target Neighborhood Hits	217	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

IRS2_HUMAN
NC score	0.032746 (rank : 317)	θ value	1.38821 (rank : 255)
Query Neighborhood Hits	370	Target Neighborhood Hits	262	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

LR37A_HUMAN
NC score	0.032698 (rank : 318)	θ value	0.365318 (rank : 230)
Query Neighborhood Hits	370	Target Neighborhood Hits	720	Shared Neighborhood Hits	52
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MBD6_HUMAN
NC score	0.032180 (rank : 319)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	370	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PTPRJ_HUMAN
NC score	0.031333 (rank : 320)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	370	Target Neighborhood Hits	207	Shared Neighborhood Hits	13
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

ACD_HUMAN
NC score	0.031197 (rank : 321)	θ value	1.81305 (rank : 261)
Query Neighborhood Hits	370	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

STRC_MOUSE
NC score	0.030899 (rank : 322)	θ value	0.0736092 (rank : 215)
Query Neighborhood Hits	370	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

RERE_HUMAN
NC score	0.029949 (rank : 323)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	370	Target Neighborhood Hits	779	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CD2_HUMAN
NC score	0.029811 (rank : 324)	θ value	3.0926 (rank : 276)
Query Neighborhood Hits	370	Target Neighborhood Hits	504	Shared Neighborhood Hits	53
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

LHX3_MOUSE
NC score	0.028401 (rank : 325)	θ value	1.06291 (rank : 253)
Query Neighborhood Hits	370	Target Neighborhood Hits	451	Shared Neighborhood Hits	21
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

DMD_HUMAN
NC score	0.026633 (rank : 326)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	370	Target Neighborhood Hits	1135	Shared Neighborhood Hits	55
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

ZN645_HUMAN
NC score	0.026354 (rank : 327)	θ value	4.03905 (rank : 312)
Query Neighborhood Hits	370	Target Neighborhood Hits	265	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

MAGD1_MOUSE
NC score	0.025649 (rank : 328)	θ value	0.0563607 (rank : 209)
Query Neighborhood Hits	370	Target Neighborhood Hits	136	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYH6, Q543L6, Q99PB5, Q9CYX1	Gene names	Maged1, Nrage
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (Dlxin-1).

RTP3_MOUSE
NC score	0.025587 (rank : 329)	θ value	5.27518 (rank : 330)
Query Neighborhood Hits	370	Target Neighborhood Hits	374	Shared Neighborhood Hits	44
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

PI5PA_MOUSE
NC score	0.024851 (rank : 330)	θ value	1.38821 (rank : 257)
Query Neighborhood Hits	370	Target Neighborhood Hits	331	Shared Neighborhood Hits	43
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BAZ2A_HUMAN
NC score	0.024790 (rank : 331)	θ value	4.03905 (rank : 291)
Query Neighborhood Hits	370	Target Neighborhood Hits	780	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

DMD_MOUSE
NC score	0.024789 (rank : 332)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	370	Target Neighborhood Hits	1111	Shared Neighborhood Hits	56
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

ANK2_HUMAN
NC score	0.024612 (rank : 333)	θ value	4.03905 (rank : 290)
Query Neighborhood Hits	370	Target Neighborhood Hits	1615	Shared Neighborhood Hits	105
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

WASF2_MOUSE
NC score	0.023563 (rank : 334)	θ value	4.03905 (rank : 309)
Query Neighborhood Hits	370	Target Neighborhood Hits	315	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

G3PT_MOUSE
NC score	0.022718 (rank : 335)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	370	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

MA1B1_HUMAN
NC score	0.022609 (rank : 336)	θ value	0.62314 (rank : 241)
Query Neighborhood Hits	370	Target Neighborhood Hits	125	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

UTRO_HUMAN
NC score	0.021694 (rank : 337)	θ value	4.03905 (rank : 308)
Query Neighborhood Hits	370	Target Neighborhood Hits	960	Shared Neighborhood Hits	46
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

GP137_MOUSE
NC score	0.021544 (rank : 338)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	370	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q60865, Q60758, Q61620	Gene names	M11s1, Gpiap, Gpiap1, Gpip137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI).

LEUK_MOUSE
NC score	0.021095 (rank : 339)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	370	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

SFR15_HUMAN
NC score	0.020989 (rank : 340)	θ value	5.27518 (rank : 331)
Query Neighborhood Hits	370	Target Neighborhood Hits	368	Shared Neighborhood Hits	33
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

MAGD1_HUMAN
NC score	0.020238 (rank : 341)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	370	Target Neighborhood Hits	130	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

HRX_HUMAN
NC score	0.020033 (rank : 342)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	370	Target Neighborhood Hits	825	Shared Neighborhood Hits	54
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

JPH2_HUMAN
NC score	0.019926 (rank : 343)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	370	Target Neighborhood Hits	639	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

PO6F2_MOUSE
NC score	0.019781 (rank : 344)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	370	Target Neighborhood Hits	639	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

NOP14_HUMAN
NC score	0.019469 (rank : 345)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	370	Target Neighborhood Hits	573	Shared Neighborhood Hits	30
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

MAML1_HUMAN
NC score	0.019328 (rank : 346)	θ value	1.38821 (rank : 256)
Query Neighborhood Hits	370	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

HGS_MOUSE
NC score	0.019286 (rank : 347)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	370	Target Neighborhood Hits	589	Shared Neighborhood Hits	51
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CDN1C_MOUSE
NC score	0.019126 (rank : 348)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	370	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

PELP1_HUMAN
NC score	0.019093 (rank : 349)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	370	Target Neighborhood Hits	596	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

MKL1_HUMAN
NC score	0.018656 (rank : 350)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	370	Target Neighborhood Hits	232	Shared Neighborhood Hits	31
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

CN037_MOUSE
NC score	0.017934 (rank : 351)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	370	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

NUFP1_HUMAN
NC score	0.017367 (rank : 352)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	370	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

RFX1_HUMAN
NC score	0.017039 (rank : 353)	θ value	1.81305 (rank : 265)
Query Neighborhood Hits	370	Target Neighborhood Hits	256	Shared Neighborhood Hits	32
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

MMAC_HUMAN
NC score	0.017013 (rank : 354)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	370	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4U1, Q5T157, Q9BRQ7	Gene names	MMACHC
Domain Architecture	No domain graphic available
Description	Methylmalonic aciduria and homocystinuria type C protein.

CLSPN_MOUSE
NC score	0.016807 (rank : 355)	θ value	2.36792 (rank : 269)
Query Neighborhood Hits	370	Target Neighborhood Hits	292	Shared Neighborhood Hits	12
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

NUP53_HUMAN
NC score	0.016594 (rank : 356)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	370	Target Neighborhood Hits	156	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

RBM6_HUMAN
NC score	0.016435 (rank : 357)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	370	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

SPF45_HUMAN
NC score	0.015450 (rank : 358)	θ value	5.27518 (rank : 332)
Query Neighborhood Hits	370	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

AB1IP_HUMAN
NC score	0.014932 (rank : 359)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	370	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

BCAR1_MOUSE
NC score	0.014835 (rank : 360)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	370	Target Neighborhood Hits	438	Shared Neighborhood Hits	50
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

THAP7_MOUSE
NC score	0.014756 (rank : 361)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	370	Target Neighborhood Hits	64	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

ETV6_HUMAN
NC score	0.014738 (rank : 362)	θ value	1.38821 (rank : 254)
Query Neighborhood Hits	370	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

BCL7A_MOUSE
NC score	0.014350 (rank : 363)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	370	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

IASPP_MOUSE
NC score	0.014237 (rank : 364)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	370	Target Neighborhood Hits	1024	Shared Neighborhood Hits	56
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

5NT1B_MOUSE
NC score	0.014178 (rank : 365)	θ value	4.03905 (rank : 289)
Query Neighborhood Hits	370	Target Neighborhood Hits	78	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

WNK2_HUMAN
NC score	0.013704 (rank : 366)	θ value	4.03905 (rank : 311)
Query Neighborhood Hits	370	Target Neighborhood Hits	1407	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

S13A3_MOUSE
NC score	0.013458 (rank : 367)	θ value	2.36792 (rank : 272)
Query Neighborhood Hits	370	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Y63	Gene names	Slc13a3, Nadc3, Sdct2
Domain Architecture
Description	Solute carrier family 13 member 3 (Sodium-dependent high-affinity dicarboxylate transporter 2) (Na(+)/dicarboxylate cotransporter 3) (NaDC-3) (mNaDC3).

CCDC9_MOUSE
NC score	0.012713 (rank : 368)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	370	Target Neighborhood Hits	196	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

SMRA3_MOUSE
NC score	0.012418 (rank : 369)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	370	Target Neighborhood Hits	267	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

MBB1A_MOUSE
NC score	0.012303 (rank : 370)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	370	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

CBLB_HUMAN
NC score	0.011791 (rank : 371)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	370	Target Neighborhood Hits	261	Shared Neighborhood Hits	15
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

FUBP3_HUMAN
NC score	0.011287 (rank : 372)	θ value	1.06291 (rank : 252)
Query Neighborhood Hits	370	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

CEP72_HUMAN
NC score	0.010398 (rank : 373)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	370	Target Neighborhood Hits	374	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

USP9X_HUMAN
NC score	0.009522 (rank : 374)	θ value	5.27518 (rank : 334)
Query Neighborhood Hits	370	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.009477 (rank : 375)	θ value	5.27518 (rank : 335)
Query Neighborhood Hits	370	Target Neighborhood Hits	171	Shared Neighborhood Hits	11
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

SYNJ2_HUMAN
NC score	0.008895 (rank : 376)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	370	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SAFB2_MOUSE
NC score	0.008874 (rank : 377)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	370	Target Neighborhood Hits	581	Shared Neighborhood Hits	22
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

PAPOG_HUMAN
NC score	0.008048 (rank : 378)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	370	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

K2C3_HUMAN
NC score	0.007976 (rank : 379)	θ value	0.62314 (rank : 240)
Query Neighborhood Hits	370	Target Neighborhood Hits	443	Shared Neighborhood Hits	13
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

MBD1_MOUSE
NC score	0.007854 (rank : 380)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	370	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

K2C1_MOUSE
NC score	0.007470 (rank : 381)	θ value	0.47712 (rank : 236)
Query Neighborhood Hits	370	Target Neighborhood Hits	477	Shared Neighborhood Hits	15
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

MYO5A_HUMAN
NC score	0.007439 (rank : 382)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	370	Target Neighborhood Hits	1092	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MAGA8_HUMAN
NC score	0.007239 (rank : 383)	θ value	3.0926 (rank : 282)
Query Neighborhood Hits	370	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	P43361	Gene names	MAGEA8, MAGE8
Domain Architecture
Description	Melanoma-associated antigen 8 (MAGE-8 antigen).

ATBF1_HUMAN
NC score	0.007033 (rank : 384)	θ value	0.0961366 (rank : 216)
Query Neighborhood Hits	370	Target Neighborhood Hits	1547	Shared Neighborhood Hits	53
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CD2L7_HUMAN
NC score	0.007019 (rank : 385)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	370	Target Neighborhood Hits	1275	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CDCP1_MOUSE
NC score	0.005825 (rank : 386)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	370	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U462, Q810J0, Q921M9	Gene names	Cdcp1
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (CD318 antigen).

WNK3_HUMAN
NC score	0.005682 (rank : 387)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	370	Target Neighborhood Hits	948	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

CENPF_HUMAN
NC score	0.005644 (rank : 388)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	370	Target Neighborhood Hits	1932	Shared Neighborhood Hits	60
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

UBP8_HUMAN
NC score	0.005608 (rank : 389)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	370	Target Neighborhood Hits	751	Shared Neighborhood Hits	36
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

MINK1_HUMAN
NC score	0.005465 (rank : 390)	θ value	3.0926 (rank : 283)
Query Neighborhood Hits	370	Target Neighborhood Hits	1477	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

M3K6_HUMAN
NC score	0.005135 (rank : 391)	θ value	2.36792 (rank : 271)
Query Neighborhood Hits	370	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

ANGL6_HUMAN
NC score	0.004884 (rank : 392)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	370	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

VMD2_HUMAN
NC score	0.004563 (rank : 393)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	370	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	O76090, O75904, Q8IUR9, Q8IZ80	Gene names	VMD2
Domain Architecture
Description	Bestrophin-1 (Vitelliform macular dystrophy protein 2) (TU15B).

SIG10_HUMAN
NC score	0.004509 (rank : 394)	θ value	2.36792 (rank : 273)
Query Neighborhood Hits	370	Target Neighborhood Hits	363	Shared Neighborhood Hits	19
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

PABP1_MOUSE
NC score	0.004339 (rank : 395)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	370	Target Neighborhood Hits	278	Shared Neighborhood Hits	19
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

M3K10_HUMAN
NC score	0.004097 (rank : 396)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	370	Target Neighborhood Hits	1071	Shared Neighborhood Hits	33
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

DCDC2_MOUSE
NC score	0.004072 (rank : 397)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	370	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

PABP1_HUMAN
NC score	0.003848 (rank : 398)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	370	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

K2C6B_MOUSE
NC score	0.003457 (rank : 399)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	370	Target Neighborhood Hits	506	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

ROBO1_MOUSE
NC score	0.003236 (rank : 400)	θ value	0.62314 (rank : 245)
Query Neighborhood Hits	370	Target Neighborhood Hits	559	Shared Neighborhood Hits	17
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

DZIP1_HUMAN
NC score	0.002694 (rank : 401)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	370	Target Neighborhood Hits	675	Shared Neighborhood Hits	19
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

TLE3_HUMAN
NC score	0.002658 (rank : 402)	θ value	5.27518 (rank : 333)
Query Neighborhood Hits	370	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

KCNQ1_HUMAN
NC score	0.002158 (rank : 403)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	370	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

TLE3_MOUSE
NC score	0.001263 (rank : 404)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	370	Target Neighborhood Hits	378	Shared Neighborhood Hits	11
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

EPHB3_MOUSE
NC score	0.000801 (rank : 405)	θ value	3.0926 (rank : 278)
Query Neighborhood Hits	370	Target Neighborhood Hits	996	Shared Neighborhood Hits	29
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB3_HUMAN
NC score	-0.000173 (rank : 406)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	370	Target Neighborhood Hits	996	Shared Neighborhood Hits	25
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

ROBO1_HUMAN
NC score	-0.000826 (rank : 407)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	370	Target Neighborhood Hits	529	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

LRP2_HUMAN
NC score	-0.003550 (rank : 408)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	370	Target Neighborhood Hits	573	Shared Neighborhood Hits	8
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LTBP3_HUMAN
NC score	-0.003687 (rank : 409)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	370	Target Neighborhood Hits	502	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ZBTB9_HUMAN
NC score	-0.006692 (rank : 410)	θ value	5.27518 (rank : 337)
Query Neighborhood Hits	370	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q96C00	Gene names	ZBTB9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

PRD16_HUMAN
NC score	-0.008208 (rank : 411)	θ value	1.81305 (rank : 264)
Query Neighborhood Hits	370	Target Neighborhood Hits	832	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

HKR3_HUMAN
NC score	-0.009326 (rank : 412)	θ value	1.81305 (rank : 262)
Query Neighborhood Hits	370	Target Neighborhood Hits	839	Shared Neighborhood Hits	13
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).