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Network neighborhood for query Sequence : MAGI2_HUMAN

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MAGI2_HUMAN
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MAGI1_HUMAN
θ value	0 (rank : 1)	NC score	0.959058 (rank : 3)
Query Neighborhood Hits	373	Target Neighborhood Hits	388	Shared Neighborhood Hits	245
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	0 (rank : 2)	NC score	0.955359 (rank : 4)
Query Neighborhood Hits	373	Target Neighborhood Hits	403	Shared Neighborhood Hits	239
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	373	Target Neighborhood Hits	373	Shared Neighborhood Hits	373
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	0 (rank : 4)	NC score	0.987701 (rank : 2)
Query Neighborhood Hits	373	Target Neighborhood Hits	370	Shared Neighborhood Hits	288
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MPDZ_HUMAN
θ value	1.09232e-21 (rank : 5)	NC score	0.701954 (rank : 5)
Query Neighborhood Hits	373	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PTN13_HUMAN
θ value	2.97466e-19 (rank : 6)	NC score	0.410734 (rank : 92)
Query Neighborhood Hits	373	Target Neighborhood Hits	471	Shared Neighborhood Hits	190
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

INADL_HUMAN
θ value	3.28887e-18 (rank : 7)	NC score	0.691816 (rank : 11)
Query Neighborhood Hits	373	Target Neighborhood Hits	260	Shared Neighborhood Hits	192
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
θ value	1.63225e-17 (rank : 8)	NC score	0.695600 (rank : 6)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	196
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

PTN13_MOUSE
θ value	2.7842e-17 (rank : 9)	NC score	0.400184 (rank : 101)
Query Neighborhood Hits	373	Target Neighborhood Hits	426	Shared Neighborhood Hits	190
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

WWC1_HUMAN
θ value	1.058e-16 (rank : 10)	NC score	0.401100 (rank : 100)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	1.058e-16 (rank : 11)	NC score	0.399147 (rank : 102)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	41
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

MPDZ_MOUSE
θ value	4.02038e-16 (rank : 12)	NC score	0.695059 (rank : 7)
Query Neighborhood Hits	373	Target Neighborhood Hits	298	Shared Neighborhood Hits	196
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PARD3_HUMAN
θ value	1.68911e-14 (rank : 13)	NC score	0.640396 (rank : 18)
Query Neighborhood Hits	373	Target Neighborhood Hits	312	Shared Neighborhood Hits	168
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
θ value	8.38298e-14 (rank : 14)	NC score	0.641784 (rank : 17)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	164
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

SAV1_MOUSE
θ value	1.09485e-13 (rank : 15)	NC score	0.461672 (rank : 78)
Query Neighborhood Hits	373	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SAV1_HUMAN
θ value	2.43908e-13 (rank : 16)	NC score	0.461489 (rank : 79)
Query Neighborhood Hits	373	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

DLG2_HUMAN
θ value	4.16044e-13 (rank : 17)	NC score	0.601115 (rank : 38)
Query Neighborhood Hits	373	Target Neighborhood Hits	279	Shared Neighborhood Hits	183
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG1_HUMAN
θ value	2.0648e-12 (rank : 18)	NC score	0.599611 (rank : 39)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	180
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	2.69671e-12 (rank : 19)	NC score	0.598061 (rank : 40)
Query Neighborhood Hits	373	Target Neighborhood Hits	285	Shared Neighborhood Hits	180
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG3_MOUSE
θ value	3.52202e-12 (rank : 20)	NC score	0.609404 (rank : 33)
Query Neighborhood Hits	373	Target Neighborhood Hits	274	Shared Neighborhood Hits	182
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
θ value	4.59992e-12 (rank : 21)	NC score	0.607831 (rank : 34)
Query Neighborhood Hits	373	Target Neighborhood Hits	269	Shared Neighborhood Hits	182
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG4_HUMAN
θ value	6.00763e-12 (rank : 22)	NC score	0.613825 (rank : 30)
Query Neighborhood Hits	373	Target Neighborhood Hits	286	Shared Neighborhood Hits	185
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

LNX2_HUMAN
θ value	6.00763e-12 (rank : 23)	NC score	0.594385 (rank : 44)
Query Neighborhood Hits	373	Target Neighborhood Hits	389	Shared Neighborhood Hits	181
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

DLG4_MOUSE
θ value	7.84624e-12 (rank : 24)	NC score	0.614718 (rank : 27)
Query Neighborhood Hits	373	Target Neighborhood Hits	282	Shared Neighborhood Hits	187
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PDZD1_MOUSE
θ value	7.84624e-12 (rank : 25)	NC score	0.628424 (rank : 24)
Query Neighborhood Hits	373	Target Neighborhood Hits	191	Shared Neighborhood Hits	156
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD2_HUMAN
θ value	1.02475e-11 (rank : 26)	NC score	0.609937 (rank : 32)
Query Neighborhood Hits	373	Target Neighborhood Hits	772	Shared Neighborhood Hits	222
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

K1849_MOUSE
θ value	1.33837e-11 (rank : 27)	NC score	0.500265 (rank : 71)
Query Neighborhood Hits	373	Target Neighborhood Hits	335	Shared Neighborhood Hits	153
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PZRN4_HUMAN
θ value	2.28291e-11 (rank : 28)	NC score	0.507850 (rank : 69)
Query Neighborhood Hits	373	Target Neighborhood Hits	438	Shared Neighborhood Hits	156
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZO3_HUMAN
θ value	2.28291e-11 (rank : 29)	NC score	0.555400 (rank : 60)
Query Neighborhood Hits	373	Target Neighborhood Hits	219	Shared Neighborhood Hits	170
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_MOUSE
θ value	2.98157e-11 (rank : 30)	NC score	0.562004 (rank : 55)
Query Neighborhood Hits	373	Target Neighborhood Hits	224	Shared Neighborhood Hits	177
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

WWOX_HUMAN
θ value	3.89403e-11 (rank : 31)	NC score	0.292767 (rank : 163)
Query Neighborhood Hits	373	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	3.89403e-11 (rank : 32)	NC score	0.290156 (rank : 166)
Query Neighborhood Hits	373	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

ITCH_MOUSE
θ value	5.08577e-11 (rank : 33)	NC score	0.307750 (rank : 155)
Query Neighborhood Hits	373	Target Neighborhood Hits	127	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

LIN7B_MOUSE
θ value	6.64225e-11 (rank : 34)	NC score	0.691854 (rank : 10)
Query Neighborhood Hits	373	Target Neighborhood Hits	200	Shared Neighborhood Hits	187
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

ITCH_HUMAN
θ value	8.67504e-11 (rank : 35)	NC score	0.305990 (rank : 159)
Query Neighborhood Hits	373	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

K1849_HUMAN
θ value	8.67504e-11 (rank : 36)	NC score	0.520490 (rank : 66)
Query Neighborhood Hits	373	Target Neighborhood Hits	220	Shared Neighborhood Hits	151
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

DLG2_MOUSE
θ value	1.47974e-10 (rank : 37)	NC score	0.597871 (rank : 41)
Query Neighborhood Hits	373	Target Neighborhood Hits	271	Shared Neighborhood Hits	181
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LIN7C_HUMAN
θ value	1.47974e-10 (rank : 38)	NC score	0.691240 (rank : 12)
Query Neighborhood Hits	373	Target Neighborhood Hits	198	Shared Neighborhood Hits	187
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	1.47974e-10 (rank : 39)	NC score	0.691240 (rank : 13)
Query Neighborhood Hits	373	Target Neighborhood Hits	198	Shared Neighborhood Hits	187
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LNX2_MOUSE
θ value	1.47974e-10 (rank : 40)	NC score	0.594273 (rank : 45)
Query Neighborhood Hits	373	Target Neighborhood Hits	407	Shared Neighborhood Hits	183
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

NEDD4_HUMAN
θ value	1.47974e-10 (rank : 41)	NC score	0.286712 (rank : 167)
Query Neighborhood Hits	373	Target Neighborhood Hits	214	Shared Neighborhood Hits	45
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

WWP2_MOUSE
θ value	1.47974e-10 (rank : 42)	NC score	0.315036 (rank : 151)
Query Neighborhood Hits	373	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

YAP1_MOUSE
θ value	1.47974e-10 (rank : 43)	NC score	0.415240 (rank : 87)
Query Neighborhood Hits	373	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PAR3L_HUMAN
θ value	1.9326e-10 (rank : 44)	NC score	0.628727 (rank : 23)
Query Neighborhood Hits	373	Target Neighborhood Hits	297	Shared Neighborhood Hits	160
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

WWP2_HUMAN
θ value	1.9326e-10 (rank : 45)	NC score	0.315267 (rank : 150)
Query Neighborhood Hits	373	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

LIN7B_HUMAN
θ value	2.52405e-10 (rank : 46)	NC score	0.692594 (rank : 9)
Query Neighborhood Hits	373	Target Neighborhood Hits	200	Shared Neighborhood Hits	187
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LNX1_HUMAN
θ value	2.52405e-10 (rank : 47)	NC score	0.585982 (rank : 49)
Query Neighborhood Hits	373	Target Neighborhood Hits	379	Shared Neighborhood Hits	173
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LAP4_HUMAN
θ value	4.30538e-10 (rank : 48)	NC score	0.430366 (rank : 81)
Query Neighborhood Hits	373	Target Neighborhood Hits	608	Shared Neighborhood Hits	208
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

WWP1_MOUSE
θ value	4.30538e-10 (rank : 49)	NC score	0.309937 (rank : 153)
Query Neighborhood Hits	373	Target Neighborhood Hits	138	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

SMUF1_MOUSE
θ value	7.34386e-10 (rank : 50)	NC score	0.291841 (rank : 165)
Query Neighborhood Hits	373	Target Neighborhood Hits	142	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

LIN7A_HUMAN
θ value	9.59137e-10 (rank : 51)	NC score	0.685878 (rank : 15)
Query Neighborhood Hits	373	Target Neighborhood Hits	193	Shared Neighborhood Hits	186
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	9.59137e-10 (rank : 52)	NC score	0.686027 (rank : 14)
Query Neighborhood Hits	373	Target Neighborhood Hits	193	Shared Neighborhood Hits	186
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

SMUF2_HUMAN
θ value	9.59137e-10 (rank : 53)	NC score	0.292418 (rank : 164)
Query Neighborhood Hits	373	Target Neighborhood Hits	142	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

NHRF2_HUMAN
θ value	1.25267e-09 (rank : 54)	NC score	0.614601 (rank : 28)
Query Neighborhood Hits	373	Target Neighborhood Hits	197	Shared Neighborhood Hits	165
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
θ value	1.25267e-09 (rank : 55)	NC score	0.605985 (rank : 37)
Query Neighborhood Hits	373	Target Neighborhood Hits	194	Shared Neighborhood Hits	166
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

WWP1_HUMAN
θ value	1.25267e-09 (rank : 56)	NC score	0.306662 (rank : 157)
Query Neighborhood Hits	373	Target Neighborhood Hits	262	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

PDZD7_HUMAN
θ value	2.79066e-09 (rank : 57)	NC score	0.676599 (rank : 16)
Query Neighborhood Hits	373	Target Neighborhood Hits	181	Shared Neighborhood Hits	170
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

GRIP2_HUMAN
θ value	3.64472e-09 (rank : 58)	NC score	0.635188 (rank : 20)
Query Neighborhood Hits	373	Target Neighborhood Hits	256	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

SNTG1_HUMAN
θ value	3.64472e-09 (rank : 59)	NC score	0.567985 (rank : 52)
Query Neighborhood Hits	373	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

LAP4_MOUSE
θ value	6.21693e-09 (rank : 60)	NC score	0.421635 (rank : 85)
Query Neighborhood Hits	373	Target Neighborhood Hits	590	Shared Neighborhood Hits	203
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LNX1_MOUSE
θ value	6.21693e-09 (rank : 61)	NC score	0.585205 (rank : 51)
Query Neighborhood Hits	373	Target Neighborhood Hits	377	Shared Neighborhood Hits	180
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

SNTG1_MOUSE
θ value	6.21693e-09 (rank : 62)	NC score	0.566824 (rank : 53)
Query Neighborhood Hits	373	Target Neighborhood Hits	179	Shared Neighborhood Hits	173
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

NEDD4_MOUSE
θ value	1.06045e-08 (rank : 63)	NC score	0.279462 (rank : 175)
Query Neighborhood Hits	373	Target Neighborhood Hits	212	Shared Neighborhood Hits	44
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NFH_MOUSE
θ value	1.06045e-08 (rank : 64)	NC score	0.057630 (rank : 269)
Query Neighborhood Hits	373	Target Neighborhood Hits	2247	Shared Neighborhood Hits	143
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CNKR2_HUMAN
θ value	1.38499e-08 (rank : 65)	NC score	0.253986 (rank : 188)
Query Neighborhood Hits	373	Target Neighborhood Hits	197	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	1.38499e-08 (rank : 66)	NC score	0.254034 (rank : 187)
Query Neighborhood Hits	373	Target Neighborhood Hits	197	Shared Neighborhood Hits	59
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

NED4L_HUMAN
θ value	1.38499e-08 (rank : 67)	NC score	0.279957 (rank : 174)
Query Neighborhood Hits	373	Target Neighborhood Hits	238	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	1.38499e-08 (rank : 68)	NC score	0.280293 (rank : 173)
Query Neighborhood Hits	373	Target Neighborhood Hits	231	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

WHRN_HUMAN
θ value	1.80886e-08 (rank : 69)	NC score	0.632943 (rank : 22)
Query Neighborhood Hits	373	Target Neighborhood Hits	325	Shared Neighborhood Hits	193
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

SYJ2B_HUMAN
θ value	2.36244e-08 (rank : 70)	NC score	0.694113 (rank : 8)
Query Neighborhood Hits	373	Target Neighborhood Hits	162	Shared Neighborhood Hits	159
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

WHRN_MOUSE
θ value	2.36244e-08 (rank : 71)	NC score	0.635082 (rank : 21)
Query Neighborhood Hits	373	Target Neighborhood Hits	412	Shared Neighborhood Hits	200
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

NHERF_MOUSE
θ value	3.08544e-08 (rank : 72)	NC score	0.606539 (rank : 36)
Query Neighborhood Hits	373	Target Neighborhood Hits	195	Shared Neighborhood Hits	159
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

SNTB2_HUMAN
θ value	3.08544e-08 (rank : 73)	NC score	0.559397 (rank : 56)
Query Neighborhood Hits	373	Target Neighborhood Hits	180	Shared Neighborhood Hits	163
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

LDB3_MOUSE
θ value	5.26297e-08 (rank : 74)	NC score	0.280644 (rank : 171)
Query Neighborhood Hits	373	Target Neighborhood Hits	510	Shared Neighborhood Hits	127
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PZRN3_HUMAN
θ value	6.87365e-08 (rank : 75)	NC score	0.477086 (rank : 76)
Query Neighborhood Hits	373	Target Neighborhood Hits	461	Shared Neighborhood Hits	155
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

APBA3_MOUSE
θ value	8.97725e-08 (rank : 76)	NC score	0.424595 (rank : 83)
Query Neighborhood Hits	373	Target Neighborhood Hits	174	Shared Neighborhood Hits	136
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SNTB2_MOUSE
θ value	8.97725e-08 (rank : 77)	NC score	0.558895 (rank : 58)
Query Neighborhood Hits	373	Target Neighborhood Hits	181	Shared Neighborhood Hits	164
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTA1_HUMAN
θ value	1.17247e-07 (rank : 78)	NC score	0.554900 (rank : 61)
Query Neighborhood Hits	373	Target Neighborhood Hits	186	Shared Neighborhood Hits	173
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
θ value	1.17247e-07 (rank : 79)	NC score	0.545991 (rank : 64)
Query Neighborhood Hits	373	Target Neighborhood Hits	170	Shared Neighborhood Hits	163
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTG2_HUMAN
θ value	1.17247e-07 (rank : 80)	NC score	0.590019 (rank : 46)
Query Neighborhood Hits	373	Target Neighborhood Hits	191	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

GRIP1_HUMAN
θ value	1.53129e-07 (rank : 81)	NC score	0.626899 (rank : 25)
Query Neighborhood Hits	373	Target Neighborhood Hits	231	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
θ value	1.99992e-07 (rank : 82)	NC score	0.622027 (rank : 26)
Query Neighborhood Hits	373	Target Neighborhood Hits	241	Shared Neighborhood Hits	193
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SMUF1_HUMAN
θ value	1.99992e-07 (rank : 83)	NC score	0.280353 (rank : 172)
Query Neighborhood Hits	373	Target Neighborhood Hits	135	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

PDLI2_HUMAN
θ value	2.61198e-07 (rank : 84)	NC score	0.471035 (rank : 77)
Query Neighborhood Hits	373	Target Neighborhood Hits	245	Shared Neighborhood Hits	132
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

SNTG2_MOUSE
θ value	2.61198e-07 (rank : 85)	NC score	0.559177 (rank : 57)
Query Neighborhood Hits	373	Target Neighborhood Hits	176	Shared Neighborhood Hits	171
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

ZO1_HUMAN
θ value	2.61198e-07 (rank : 86)	NC score	0.497904 (rank : 72)
Query Neighborhood Hits	373	Target Neighborhood Hits	474	Shared Neighborhood Hits	184
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

PDZD1_HUMAN
θ value	5.81887e-07 (rank : 87)	NC score	0.614558 (rank : 29)
Query Neighborhood Hits	373	Target Neighborhood Hits	190	Shared Neighborhood Hits	153
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PZRN3_MOUSE
θ value	5.81887e-07 (rank : 88)	NC score	0.479476 (rank : 75)
Query Neighborhood Hits	373	Target Neighborhood Hits	447	Shared Neighborhood Hits	153
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

USH1C_HUMAN
θ value	7.59969e-07 (rank : 89)	NC score	0.639281 (rank : 19)
Query Neighborhood Hits	373	Target Neighborhood Hits	327	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

PKHA5_HUMAN
θ value	9.92553e-07 (rank : 90)	NC score	0.241571 (rank : 190)
Query Neighborhood Hits	373	Target Neighborhood Hits	455	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

NEB2_HUMAN
θ value	1.29631e-06 (rank : 91)	NC score	0.368328 (rank : 112)
Query Neighborhood Hits	373	Target Neighborhood Hits	883	Shared Neighborhood Hits	146
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	1.29631e-06 (rank : 92)	NC score	0.366005 (rank : 113)
Query Neighborhood Hits	373	Target Neighborhood Hits	889	Shared Neighborhood Hits	150
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SYNP2_HUMAN
θ value	1.29631e-06 (rank : 93)	NC score	0.343054 (rank : 122)
Query Neighborhood Hits	373	Target Neighborhood Hits	323	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

ARHGB_HUMAN
θ value	1.69304e-06 (rank : 94)	NC score	0.330204 (rank : 132)
Query Neighborhood Hits	373	Target Neighborhood Hits	375	Shared Neighborhood Hits	162
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

NHERF_HUMAN
θ value	1.69304e-06 (rank : 95)	NC score	0.590012 (rank : 47)
Query Neighborhood Hits	373	Target Neighborhood Hits	190	Shared Neighborhood Hits	155
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD3_HUMAN
θ value	1.69304e-06 (rank : 96)	NC score	0.564412 (rank : 54)
Query Neighborhood Hits	373	Target Neighborhood Hits	180	Shared Neighborhood Hits	158
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

ZO1_MOUSE
θ value	1.69304e-06 (rank : 97)	NC score	0.503015 (rank : 70)
Query Neighborhood Hits	373	Target Neighborhood Hits	453	Shared Neighborhood Hits	188
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

NEB1_HUMAN
θ value	2.21117e-06 (rank : 98)	NC score	0.392947 (rank : 108)
Query Neighborhood Hits	373	Target Neighborhood Hits	829	Shared Neighborhood Hits	166
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PTN4_HUMAN
θ value	2.88788e-06 (rank : 99)	NC score	0.169998 (rank : 207)
Query Neighborhood Hits	373	Target Neighborhood Hits	303	Shared Neighborhood Hits	126
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PDLI2_MOUSE
θ value	3.77169e-06 (rank : 100)	NC score	0.450836 (rank : 80)
Query Neighborhood Hits	373	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI5_MOUSE
θ value	3.77169e-06 (rank : 101)	NC score	0.272864 (rank : 178)
Query Neighborhood Hits	373	Target Neighborhood Hits	287	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

APBA3_HUMAN
θ value	4.92598e-06 (rank : 102)	NC score	0.429199 (rank : 82)
Query Neighborhood Hits	373	Target Neighborhood Hits	201	Shared Neighborhood Hits	143
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

MAST3_HUMAN
θ value	4.92598e-06 (rank : 103)	NC score	0.082287 (rank : 244)
Query Neighborhood Hits	373	Target Neighborhood Hits	1128	Shared Neighborhood Hits	148
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

SYNP2_MOUSE
θ value	4.92598e-06 (rank : 104)	NC score	0.381994 (rank : 109)
Query Neighborhood Hits	373	Target Neighborhood Hits	252	Shared Neighborhood Hits	130
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

USH1C_MOUSE
θ value	4.92598e-06 (rank : 105)	NC score	0.594619 (rank : 42)
Query Neighborhood Hits	373	Target Neighborhood Hits	557	Shared Neighborhood Hits	207
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PDLI5_HUMAN
θ value	6.43352e-06 (rank : 106)	NC score	0.271522 (rank : 179)
Query Neighborhood Hits	373	Target Neighborhood Hits	322	Shared Neighborhood Hits	121
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

IL16_HUMAN
θ value	8.40245e-06 (rank : 107)	NC score	0.588434 (rank : 48)
Query Neighborhood Hits	373	Target Neighborhood Hits	207	Shared Neighborhood Hits	150
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDLI7_HUMAN
θ value	8.40245e-06 (rank : 108)	NC score	0.257285 (rank : 186)
Query Neighborhood Hits	373	Target Neighborhood Hits	547	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

GOPC_HUMAN
θ value	1.09739e-05 (rank : 109)	NC score	0.585332 (rank : 50)
Query Neighborhood Hits	373	Target Neighborhood Hits	377	Shared Neighborhood Hits	174
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	1.09739e-05 (rank : 110)	NC score	0.594548 (rank : 43)
Query Neighborhood Hits	373	Target Neighborhood Hits	323	Shared Neighborhood Hits	174
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LDB3_HUMAN
θ value	1.09739e-05 (rank : 111)	NC score	0.277421 (rank : 176)
Query Neighborhood Hits	373	Target Neighborhood Hits	497	Shared Neighborhood Hits	133
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

SNTB1_HUMAN
θ value	1.09739e-05 (rank : 112)	NC score	0.519924 (rank : 67)
Query Neighborhood Hits	373	Target Neighborhood Hits	157	Shared Neighborhood Hits	152
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	1.09739e-05 (rank : 113)	NC score	0.516424 (rank : 68)
Query Neighborhood Hits	373	Target Neighborhood Hits	160	Shared Neighborhood Hits	151
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SYP2L_MOUSE
θ value	1.87187e-05 (rank : 114)	NC score	0.348161 (rank : 119)
Query Neighborhood Hits	373	Target Neighborhood Hits	289	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

YAP1_HUMAN
θ value	1.87187e-05 (rank : 115)	NC score	0.319076 (rank : 145)
Query Neighborhood Hits	373	Target Neighborhood Hits	173	Shared Neighborhood Hits	58
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

APBA1_HUMAN
θ value	2.44474e-05 (rank : 116)	NC score	0.422477 (rank : 84)
Query Neighborhood Hits	373	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CSKP_HUMAN
θ value	2.44474e-05 (rank : 117)	NC score	0.131622 (rank : 223)
Query Neighborhood Hits	373	Target Neighborhood Hits	1022	Shared Neighborhood Hits	132
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	2.44474e-05 (rank : 118)	NC score	0.128846 (rank : 224)
Query Neighborhood Hits	373	Target Neighborhood Hits	1027	Shared Neighborhood Hits	132
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

PDZD3_MOUSE
θ value	2.44474e-05 (rank : 119)	NC score	0.535989 (rank : 65)
Query Neighborhood Hits	373	Target Neighborhood Hits	171	Shared Neighborhood Hits	155
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SYP2L_HUMAN
θ value	2.44474e-05 (rank : 120)	NC score	0.411963 (rank : 91)
Query Neighborhood Hits	373	Target Neighborhood Hits	400	Shared Neighborhood Hits	154
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PDZ11_HUMAN
θ value	3.19293e-05 (rank : 121)	NC score	0.611436 (rank : 31)
Query Neighborhood Hits	373	Target Neighborhood Hits	160	Shared Neighborhood Hits	145
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	3.19293e-05 (rank : 122)	NC score	0.607028 (rank : 35)
Query Neighborhood Hits	373	Target Neighborhood Hits	154	Shared Neighborhood Hits	138
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PTN3_HUMAN
θ value	3.19293e-05 (rank : 123)	NC score	0.169241 (rank : 208)
Query Neighborhood Hits	373	Target Neighborhood Hits	258	Shared Neighborhood Hits	116
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SHAN1_HUMAN
θ value	3.19293e-05 (rank : 124)	NC score	0.217296 (rank : 194)
Query Neighborhood Hits	373	Target Neighborhood Hits	1041	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ARHGC_HUMAN
θ value	4.1701e-05 (rank : 125)	NC score	0.303325 (rank : 161)
Query Neighborhood Hits	373	Target Neighborhood Hits	351	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

MAST4_HUMAN
θ value	4.1701e-05 (rank : 126)	NC score	0.085679 (rank : 242)
Query Neighborhood Hits	373	Target Neighborhood Hits	1804	Shared Neighborhood Hits	191
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

STXB4_HUMAN
θ value	5.44631e-05 (rank : 127)	NC score	0.418466 (rank : 86)
Query Neighborhood Hits	373	Target Neighborhood Hits	616	Shared Neighborhood Hits	142
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SHAN2_HUMAN
θ value	7.1131e-05 (rank : 128)	NC score	0.341830 (rank : 124)
Query Neighborhood Hits	373	Target Neighborhood Hits	346	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

ARHGC_MOUSE
θ value	9.29e-05 (rank : 129)	NC score	0.299647 (rank : 162)
Query Neighborhood Hits	373	Target Neighborhood Hits	344	Shared Neighborhood Hits	150
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

WWTR1_HUMAN
θ value	9.29e-05 (rank : 130)	NC score	0.304663 (rank : 160)
Query Neighborhood Hits	373	Target Neighborhood Hits	76	Shared Neighborhood Hits	42
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

ZO2_HUMAN
θ value	9.29e-05 (rank : 131)	NC score	0.483154 (rank : 73)
Query Neighborhood Hits	373	Target Neighborhood Hits	289	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	9.29e-05 (rank : 132)	NC score	0.479695 (rank : 74)
Query Neighborhood Hits	373	Target Neighborhood Hits	296	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

MPP3_MOUSE
θ value	0.000121331 (rank : 133)	NC score	0.401410 (rank : 98)
Query Neighborhood Hits	373	Target Neighborhood Hits	165	Shared Neighborhood Hits	134
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

PDLI7_MOUSE
θ value	0.000158464 (rank : 134)	NC score	0.249393 (rank : 189)
Query Neighborhood Hits	373	Target Neighborhood Hits	279	Shared Neighborhood Hits	109
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

WWTR1_MOUSE
θ value	0.000158464 (rank : 135)	NC score	0.306625 (rank : 158)
Query Neighborhood Hits	373	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

BAG3_MOUSE
θ value	0.00020696 (rank : 136)	NC score	0.240348 (rank : 191)
Query Neighborhood Hits	373	Target Neighborhood Hits	513	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

STXB4_MOUSE
θ value	0.00020696 (rank : 137)	NC score	0.412424 (rank : 90)
Query Neighborhood Hits	373	Target Neighborhood Hits	629	Shared Neighborhood Hits	139
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

APBA2_HUMAN
θ value	0.000270298 (rank : 138)	NC score	0.401828 (rank : 97)
Query Neighborhood Hits	373	Target Neighborhood Hits	220	Shared Neighborhood Hits	147
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.000270298 (rank : 139)	NC score	0.401259 (rank : 99)
Query Neighborhood Hits	373	Target Neighborhood Hits	219	Shared Neighborhood Hits	147
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

BAG3_HUMAN
θ value	0.000270298 (rank : 140)	NC score	0.265489 (rank : 183)
Query Neighborhood Hits	373	Target Neighborhood Hits	314	Shared Neighborhood Hits	61
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

LRRC7_HUMAN
θ value	0.000270298 (rank : 141)	NC score	0.216584 (rank : 195)
Query Neighborhood Hits	373	Target Neighborhood Hits	423	Shared Neighborhood Hits	119
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.000270298 (rank : 142)	NC score	0.215572 (rank : 196)
Query Neighborhood Hits	373	Target Neighborhood Hits	416	Shared Neighborhood Hits	119
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PCLO_MOUSE
θ value	0.000270298 (rank : 143)	NC score	0.203117 (rank : 198)
Query Neighborhood Hits	373	Target Neighborhood Hits	2275	Shared Neighborhood Hits	229
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SHAN2_MOUSE
θ value	0.000270298 (rank : 144)	NC score	0.306888 (rank : 156)
Query Neighborhood Hits	373	Target Neighborhood Hits	446	Shared Neighborhood Hits	136
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

IL16_MOUSE
θ value	0.00035302 (rank : 145)	NC score	0.553459 (rank : 62)
Query Neighborhood Hits	373	Target Neighborhood Hits	189	Shared Neighborhood Hits	143
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PICK1_MOUSE
θ value	0.00035302 (rank : 146)	NC score	0.405656 (rank : 95)
Query Neighborhood Hits	373	Target Neighborhood Hits	131	Shared Neighborhood Hits	122
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

MAST1_HUMAN
θ value	0.000461057 (rank : 147)	NC score	0.079990 (rank : 248)
Query Neighborhood Hits	373	Target Neighborhood Hits	1146	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	0.000461057 (rank : 148)	NC score	0.080853 (rank : 246)
Query Neighborhood Hits	373	Target Neighborhood Hits	1123	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MPP3_HUMAN
θ value	0.000461057 (rank : 149)	NC score	0.395780 (rank : 104)
Query Neighborhood Hits	373	Target Neighborhood Hits	171	Shared Neighborhood Hits	134
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

PICK1_HUMAN
θ value	0.000461057 (rank : 150)	NC score	0.404350 (rank : 96)
Query Neighborhood Hits	373	Target Neighborhood Hits	132	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

MAST2_HUMAN
θ value	0.000602161 (rank : 151)	NC score	0.080095 (rank : 247)
Query Neighborhood Hits	373	Target Neighborhood Hits	1189	Shared Neighborhood Hits	141
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	0.000602161 (rank : 152)	NC score	0.078365 (rank : 250)
Query Neighborhood Hits	373	Target Neighborhood Hits	1110	Shared Neighborhood Hits	137
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MPP6_MOUSE
θ value	0.000786445 (rank : 153)	NC score	0.323709 (rank : 139)
Query Neighborhood Hits	373	Target Neighborhood Hits	187	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

PDLI3_HUMAN
θ value	0.000786445 (rank : 154)	NC score	0.337634 (rank : 127)
Query Neighborhood Hits	373	Target Neighborhood Hits	199	Shared Neighborhood Hits	110
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PSCBP_HUMAN
θ value	0.000786445 (rank : 155)	NC score	0.394991 (rank : 106)
Query Neighborhood Hits	373	Target Neighborhood Hits	123	Shared Neighborhood Hits	113
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RGS3_HUMAN
θ value	0.000786445 (rank : 156)	NC score	0.109943 (rank : 228)
Query Neighborhood Hits	373	Target Neighborhood Hits	1375	Shared Neighborhood Hits	136
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PDLI1_MOUSE
θ value	0.00102713 (rank : 157)	NC score	0.332023 (rank : 131)
Query Neighborhood Hits	373	Target Neighborhood Hits	213	Shared Neighborhood Hits	107
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PSCBP_MOUSE
θ value	0.00102713 (rank : 158)	NC score	0.410378 (rank : 93)
Query Neighborhood Hits	373	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

MPP5_HUMAN
θ value	0.00134147 (rank : 159)	NC score	0.395558 (rank : 105)
Query Neighborhood Hits	373	Target Neighborhood Hits	231	Shared Neighborhood Hits	141
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

RHPN1_MOUSE
θ value	0.00134147 (rank : 160)	NC score	0.358708 (rank : 117)
Query Neighborhood Hits	373	Target Neighborhood Hits	154	Shared Neighborhood Hits	129
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

EM55_HUMAN
θ value	0.00175202 (rank : 161)	NC score	0.368909 (rank : 111)
Query Neighborhood Hits	373	Target Neighborhood Hits	228	Shared Neighborhood Hits	130
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

MPP5_MOUSE
θ value	0.00175202 (rank : 162)	NC score	0.393859 (rank : 107)
Query Neighborhood Hits	373	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP6_HUMAN
θ value	0.00175202 (rank : 163)	NC score	0.318364 (rank : 146)
Query Neighborhood Hits	373	Target Neighborhood Hits	180	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

EM55_MOUSE
θ value	0.00228821 (rank : 164)	NC score	0.364225 (rank : 114)
Query Neighborhood Hits	373	Target Neighborhood Hits	221	Shared Neighborhood Hits	128
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

GIPC1_MOUSE
θ value	0.00298849 (rank : 165)	NC score	0.277394 (rank : 177)
Query Neighborhood Hits	373	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

LIMK1_MOUSE
θ value	0.00298849 (rank : 166)	NC score	0.044458 (rank : 299)
Query Neighborhood Hits	373	Target Neighborhood Hits	1008	Shared Neighborhood Hits	92
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

APXL_HUMAN
θ value	0.00390308 (rank : 167)	NC score	0.340443 (rank : 125)
Query Neighborhood Hits	373	Target Neighborhood Hits	553	Shared Neighborhood Hits	129
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

GIPC1_HUMAN
θ value	0.00390308 (rank : 168)	NC score	0.265766 (rank : 182)
Query Neighborhood Hits	373	Target Neighborhood Hits	91	Shared Neighborhood Hits	88
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

PAR6G_MOUSE
θ value	0.00390308 (rank : 169)	NC score	0.343523 (rank : 120)
Query Neighborhood Hits	373	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

TX1B3_HUMAN
θ value	0.00509761 (rank : 170)	NC score	0.556025 (rank : 59)
Query Neighborhood Hits	373	Target Neighborhood Hits	161	Shared Neighborhood Hits	153
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.00509761 (rank : 171)	NC score	0.552210 (rank : 63)
Query Neighborhood Hits	373	Target Neighborhood Hits	158	Shared Neighborhood Hits	150
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PDLI1_HUMAN
θ value	0.00665767 (rank : 172)	NC score	0.324692 (rank : 138)
Query Neighborhood Hits	373	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI4_HUMAN
θ value	0.00665767 (rank : 173)	NC score	0.326481 (rank : 136)
Query Neighborhood Hits	373	Target Neighborhood Hits	245	Shared Neighborhood Hits	114
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

LAP2_HUMAN
θ value	0.00869519 (rank : 174)	NC score	0.196528 (rank : 199)
Query Neighborhood Hits	373	Target Neighborhood Hits	499	Shared Neighborhood Hits	116
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MPP2_HUMAN
θ value	0.00869519 (rank : 175)	NC score	0.315936 (rank : 148)
Query Neighborhood Hits	373	Target Neighborhood Hits	173	Shared Neighborhood Hits	97
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MY18A_MOUSE
θ value	0.00869519 (rank : 176)	NC score	0.082765 (rank : 243)
Query Neighborhood Hits	373	Target Neighborhood Hits	1989	Shared Neighborhood Hits	165
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PDLI4_MOUSE
θ value	0.00869519 (rank : 177)	NC score	0.325068 (rank : 137)
Query Neighborhood Hits	373	Target Neighborhood Hits	233	Shared Neighborhood Hits	116
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

RPGF6_HUMAN
θ value	0.00869519 (rank : 178)	NC score	0.336970 (rank : 129)
Query Neighborhood Hits	373	Target Neighborhood Hits	266	Shared Neighborhood Hits	155
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

AFAD_HUMAN
θ value	0.0113563 (rank : 179)	NC score	0.397620 (rank : 103)
Query Neighborhood Hits	373	Target Neighborhood Hits	689	Shared Neighborhood Hits	149
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

MPP2_MOUSE
θ value	0.0113563 (rank : 180)	NC score	0.319085 (rank : 144)
Query Neighborhood Hits	373	Target Neighborhood Hits	189	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

PDLI3_MOUSE
θ value	0.0113563 (rank : 181)	NC score	0.313344 (rank : 152)
Query Neighborhood Hits	373	Target Neighborhood Hits	197	Shared Neighborhood Hits	106
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

CNKR1_HUMAN
θ value	0.0148317 (rank : 182)	NC score	0.122428 (rank : 225)
Query Neighborhood Hits	373	Target Neighborhood Hits	154	Shared Neighborhood Hits	26
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

DLG5_HUMAN
θ value	0.0148317 (rank : 183)	NC score	0.360508 (rank : 115)
Query Neighborhood Hits	373	Target Neighborhood Hits	1088	Shared Neighborhood Hits	199
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GRASP_HUMAN
θ value	0.0148317 (rank : 184)	NC score	0.414725 (rank : 88)
Query Neighborhood Hits	373	Target Neighborhood Hits	147	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

CGRE1_HUMAN
θ value	0.0193708 (rank : 185)	NC score	0.045564 (rank : 297)
Query Neighborhood Hits	373	Target Neighborhood Hits	354	Shared Neighborhood Hits	25
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

DVL1L_HUMAN
θ value	0.0193708 (rank : 186)	NC score	0.327546 (rank : 135)
Query Neighborhood Hits	373	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL3_HUMAN
θ value	0.0193708 (rank : 187)	NC score	0.342482 (rank : 123)
Query Neighborhood Hits	373	Target Neighborhood Hits	194	Shared Neighborhood Hits	124
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	0.0193708 (rank : 188)	NC score	0.343158 (rank : 121)
Query Neighborhood Hits	373	Target Neighborhood Hits	198	Shared Neighborhood Hits	127
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

GIPC2_HUMAN
θ value	0.0193708 (rank : 189)	NC score	0.226472 (rank : 193)
Query Neighborhood Hits	373	Target Neighborhood Hits	93	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

LIMK1_HUMAN
θ value	0.0193708 (rank : 190)	NC score	0.043824 (rank : 300)
Query Neighborhood Hits	373	Target Neighborhood Hits	1005	Shared Neighborhood Hits	89
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

MPP4_HUMAN
θ value	0.0193708 (rank : 191)	NC score	0.407778 (rank : 94)
Query Neighborhood Hits	373	Target Neighborhood Hits	205	Shared Neighborhood Hits	142
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

NOS1_HUMAN
θ value	0.0193708 (rank : 192)	NC score	0.269827 (rank : 181)
Query Neighborhood Hits	373	Target Neighborhood Hits	218	Shared Neighborhood Hits	140
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

DVL1_MOUSE
θ value	0.0252991 (rank : 193)	NC score	0.337240 (rank : 128)
Query Neighborhood Hits	373	Target Neighborhood Hits	146	Shared Neighborhood Hits	119
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GRASP_MOUSE
θ value	0.0252991 (rank : 194)	NC score	0.413980 (rank : 89)
Query Neighborhood Hits	373	Target Neighborhood Hits	131	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

DVL1_HUMAN
θ value	0.0330416 (rank : 195)	NC score	0.339972 (rank : 126)
Query Neighborhood Hits	373	Target Neighborhood Hits	158	Shared Neighborhood Hits	120
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

LAP2_MOUSE
θ value	0.0330416 (rank : 196)	NC score	0.184363 (rank : 203)
Query Neighborhood Hits	373	Target Neighborhood Hits	482	Shared Neighborhood Hits	114
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

RGS3_MOUSE
θ value	0.0330416 (rank : 197)	NC score	0.098592 (rank : 233)
Query Neighborhood Hits	373	Target Neighborhood Hits	1621	Shared Neighborhood Hits	151
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHPN1_HUMAN
θ value	0.0330416 (rank : 198)	NC score	0.315461 (rank : 149)
Query Neighborhood Hits	373	Target Neighborhood Hits	158	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GIPC2_MOUSE
θ value	0.0431538 (rank : 199)	NC score	0.174074 (rank : 205)
Query Neighborhood Hits	373	Target Neighborhood Hits	71	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

MY18A_HUMAN
θ value	0.0431538 (rank : 200)	NC score	0.073751 (rank : 254)
Query Neighborhood Hits	373	Target Neighborhood Hits	1929	Shared Neighborhood Hits	165
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PAR6G_HUMAN
θ value	0.0431538 (rank : 201)	NC score	0.334337 (rank : 130)
Query Neighborhood Hits	373	Target Neighborhood Hits	159	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PDZK4_MOUSE
θ value	0.0431538 (rank : 202)	NC score	0.356369 (rank : 118)
Query Neighborhood Hits	373	Target Neighborhood Hits	165	Shared Neighborhood Hits	121
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

RGS12_HUMAN
θ value	0.0431538 (rank : 203)	NC score	0.281813 (rank : 170)
Query Neighborhood Hits	373	Target Neighborhood Hits	333	Shared Neighborhood Hits	145
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

GIPC3_HUMAN
θ value	0.0563607 (rank : 204)	NC score	0.177865 (rank : 204)
Query Neighborhood Hits	373	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	0.0563607 (rank : 205)	NC score	0.171224 (rank : 206)
Query Neighborhood Hits	373	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

DVL2_HUMAN
θ value	0.0736092 (rank : 206)	NC score	0.321403 (rank : 142)
Query Neighborhood Hits	373	Target Neighborhood Hits	223	Shared Neighborhood Hits	121
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	0.0736092 (rank : 207)	NC score	0.320099 (rank : 143)
Query Neighborhood Hits	373	Target Neighborhood Hits	233	Shared Neighborhood Hits	122
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PAR6A_MOUSE
θ value	0.0736092 (rank : 208)	NC score	0.321877 (rank : 140)
Query Neighborhood Hits	373	Target Neighborhood Hits	115	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

NCOR2_MOUSE
θ value	0.0961366 (rank : 209)	NC score	0.051638 (rank : 285)
Query Neighborhood Hits	373	Target Neighborhood Hits	790	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NET2_HUMAN
θ value	0.0961366 (rank : 210)	NC score	0.008949 (rank : 394)
Query Neighborhood Hits	373	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

PDZK4_HUMAN
θ value	0.0961366 (rank : 211)	NC score	0.359090 (rank : 116)
Query Neighborhood Hits	373	Target Neighborhood Hits	165	Shared Neighborhood Hits	116
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

CF150_HUMAN
θ value	0.125558 (rank : 212)	NC score	0.052184 (rank : 282)
Query Neighborhood Hits	373	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

IF4G1_MOUSE
θ value	0.125558 (rank : 213)	NC score	0.033859 (rank : 312)
Query Neighborhood Hits	373	Target Neighborhood Hits	534	Shared Neighborhood Hits	51
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

KGUA_MOUSE
θ value	0.125558 (rank : 214)	NC score	0.259348 (rank : 185)
Query Neighborhood Hits	373	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

MPP4_MOUSE
θ value	0.125558 (rank : 215)	NC score	0.371418 (rank : 110)
Query Neighborhood Hits	373	Target Neighborhood Hits	188	Shared Neighborhood Hits	123
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

CBP_MOUSE
θ value	0.163984 (rank : 216)	NC score	0.055032 (rank : 274)
Query Neighborhood Hits	373	Target Neighborhood Hits	1051	Shared Neighborhood Hits	88
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

KGUA_HUMAN
θ value	0.163984 (rank : 217)	NC score	0.262332 (rank : 184)
Query Neighborhood Hits	373	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LEF1_HUMAN
θ value	0.21417 (rank : 218)	NC score	0.019581 (rank : 349)
Query Neighborhood Hits	373	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

MAGD1_HUMAN
θ value	0.21417 (rank : 219)	NC score	0.020840 (rank : 340)
Query Neighborhood Hits	373	Target Neighborhood Hits	130	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

PAR6A_HUMAN
θ value	0.21417 (rank : 220)	NC score	0.318214 (rank : 147)
Query Neighborhood Hits	373	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

AFF1_HUMAN
θ value	0.279714 (rank : 221)	NC score	0.054669 (rank : 276)
Query Neighborhood Hits	373	Target Neighborhood Hits	506	Shared Neighborhood Hits	56
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

SF3B1_HUMAN
θ value	0.279714 (rank : 222)	NC score	0.045971 (rank : 296)
Query Neighborhood Hits	373	Target Neighborhood Hits	341	Shared Neighborhood Hits	35
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.279714 (rank : 223)	NC score	0.046020 (rank : 295)
Query Neighborhood Hits	373	Target Neighborhood Hits	352	Shared Neighborhood Hits	36
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CBP_HUMAN
θ value	0.365318 (rank : 224)	NC score	0.052834 (rank : 281)
Query Neighborhood Hits	373	Target Neighborhood Hits	941	Shared Neighborhood Hits	81
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NOS1_MOUSE
θ value	0.365318 (rank : 225)	NC score	0.235761 (rank : 192)
Query Neighborhood Hits	373	Target Neighborhood Hits	155	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

RIMS2_HUMAN
θ value	0.365318 (rank : 226)	NC score	0.186469 (rank : 201)
Query Neighborhood Hits	373	Target Neighborhood Hits	342	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.365318 (rank : 227)	NC score	0.185734 (rank : 202)
Query Neighborhood Hits	373	Target Neighborhood Hits	376	Shared Neighborhood Hits	118
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RPGF2_HUMAN
θ value	0.365318 (rank : 228)	NC score	0.284257 (rank : 168)
Query Neighborhood Hits	373	Target Neighborhood Hits	242	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

CAC1A_MOUSE
θ value	0.47712 (rank : 229)	NC score	0.019841 (rank : 346)
Query Neighborhood Hits	373	Target Neighborhood Hits	267	Shared Neighborhood Hits	36
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

OGFR_HUMAN
θ value	0.47712 (rank : 230)	NC score	0.053069 (rank : 279)
Query Neighborhood Hits	373	Target Neighborhood Hits	1582	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SDCB1_MOUSE
θ value	0.47712 (rank : 231)	NC score	0.321625 (rank : 141)
Query Neighborhood Hits	373	Target Neighborhood Hits	144	Shared Neighborhood Hits	134
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

CASC3_MOUSE
θ value	0.62314 (rank : 232)	NC score	0.045377 (rank : 298)
Query Neighborhood Hits	373	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CS021_HUMAN
θ value	0.62314 (rank : 233)	NC score	0.023918 (rank : 332)
Query Neighborhood Hits	373	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

GT2D1_HUMAN
θ value	0.62314 (rank : 234)	NC score	0.018485 (rank : 353)
Query Neighborhood Hits	373	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

LR37A_HUMAN
θ value	0.62314 (rank : 235)	NC score	0.029676 (rank : 319)
Query Neighborhood Hits	373	Target Neighborhood Hits	720	Shared Neighborhood Hits	52
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MAGD1_MOUSE
θ value	0.62314 (rank : 236)	NC score	0.026109 (rank : 327)
Query Neighborhood Hits	373	Target Neighborhood Hits	136	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QYH6, Q543L6, Q99PB5, Q9CYX1	Gene names	Maged1, Nrage
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (Dlxin-1).

PAR6B_HUMAN
θ value	0.62314 (rank : 237)	NC score	0.329214 (rank : 133)
Query Neighborhood Hits	373	Target Neighborhood Hits	126	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	0.62314 (rank : 238)	NC score	0.328039 (rank : 134)
Query Neighborhood Hits	373	Target Neighborhood Hits	128	Shared Neighborhood Hits	121
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PDZD6_HUMAN
θ value	0.62314 (rank : 239)	NC score	0.161989 (rank : 211)
Query Neighborhood Hits	373	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

TARA_HUMAN
θ value	0.62314 (rank : 240)	NC score	0.060209 (rank : 265)
Query Neighborhood Hits	373	Target Neighborhood Hits	1626	Shared Neighborhood Hits	107
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MDC1_HUMAN
θ value	0.813845 (rank : 241)	NC score	0.058388 (rank : 267)
Query Neighborhood Hits	373	Target Neighborhood Hits	1446	Shared Neighborhood Hits	105
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

OGFR_MOUSE
θ value	0.813845 (rank : 242)	NC score	0.038792 (rank : 306)
Query Neighborhood Hits	373	Target Neighborhood Hits	584	Shared Neighborhood Hits	55
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

RIMS1_HUMAN
θ value	0.813845 (rank : 243)	NC score	0.213499 (rank : 197)
Query Neighborhood Hits	373	Target Neighborhood Hits	437	Shared Neighborhood Hits	145
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SDCB2_MOUSE
θ value	0.813845 (rank : 244)	NC score	0.282596 (rank : 169)
Query Neighborhood Hits	373	Target Neighborhood Hits	118	Shared Neighborhood Hits	111
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

GASP2_MOUSE
θ value	1.06291 (rank : 245)	NC score	0.019642 (rank : 348)
Query Neighborhood Hits	373	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

LEF1_MOUSE
θ value	1.06291 (rank : 246)	NC score	0.015283 (rank : 359)
Query Neighborhood Hits	373	Target Neighborhood Hits	161	Shared Neighborhood Hits	7
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

PO6F2_MOUSE
θ value	1.06291 (rank : 247)	NC score	0.020812 (rank : 342)
Query Neighborhood Hits	373	Target Neighborhood Hits	639	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

SPEG_HUMAN
θ value	1.06291 (rank : 248)	NC score	0.012123 (rank : 377)
Query Neighborhood Hits	373	Target Neighborhood Hits	1762	Shared Neighborhood Hits	91
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZN385_HUMAN
θ value	1.06291 (rank : 249)	NC score	0.022491 (rank : 336)
Query Neighborhood Hits	373	Target Neighborhood Hits	614	Shared Neighborhood Hits	45
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

AATK_MOUSE
θ value	1.38821 (rank : 250)	NC score	0.002618 (rank : 408)
Query Neighborhood Hits	373	Target Neighborhood Hits	942	Shared Neighborhood Hits	40
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

CTRO_MOUSE
θ value	1.38821 (rank : 251)	NC score	0.015034 (rank : 361)
Query Neighborhood Hits	373	Target Neighborhood Hits	2344	Shared Neighborhood Hits	74
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

K2C1_MOUSE
θ value	1.38821 (rank : 252)	NC score	0.009848 (rank : 390)
Query Neighborhood Hits	373	Target Neighborhood Hits	477	Shared Neighborhood Hits	22
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

MA1B1_HUMAN
θ value	1.38821 (rank : 253)	NC score	0.020975 (rank : 339)
Query Neighborhood Hits	373	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

PAK4_MOUSE
θ value	1.38821 (rank : 254)	NC score	0.008653 (rank : 397)
Query Neighborhood Hits	373	Target Neighborhood Hits	1098	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

RBM6_HUMAN
θ value	1.38821 (rank : 255)	NC score	0.020418 (rank : 344)
Query Neighborhood Hits	373	Target Neighborhood Hits	221	Shared Neighborhood Hits	10
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

ROBO1_MOUSE
θ value	1.38821 (rank : 256)	NC score	0.001875 (rank : 411)
Query Neighborhood Hits	373	Target Neighborhood Hits	559	Shared Neighborhood Hits	21
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

SDCB2_HUMAN
θ value	1.38821 (rank : 257)	NC score	0.270153 (rank : 180)
Query Neighborhood Hits	373	Target Neighborhood Hits	121	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

ANGL6_HUMAN
θ value	1.81305 (rank : 258)	NC score	0.005776 (rank : 405)
Query Neighborhood Hits	373	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

BAZ2A_HUMAN
θ value	1.81305 (rank : 259)	NC score	0.021254 (rank : 338)
Query Neighborhood Hits	373	Target Neighborhood Hits	780	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CCDC9_HUMAN
θ value	1.81305 (rank : 260)	NC score	0.024847 (rank : 330)
Query Neighborhood Hits	373	Target Neighborhood Hits	175	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

IRS2_HUMAN
θ value	1.81305 (rank : 261)	NC score	0.034914 (rank : 309)
Query Neighborhood Hits	373	Target Neighborhood Hits	262	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

K2C3_HUMAN
θ value	1.81305 (rank : 262)	NC score	0.010280 (rank : 388)
Query Neighborhood Hits	373	Target Neighborhood Hits	443	Shared Neighborhood Hits	17
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

LHX3_MOUSE
θ value	1.81305 (rank : 263)	NC score	0.030578 (rank : 316)
Query Neighborhood Hits	373	Target Neighborhood Hits	451	Shared Neighborhood Hits	24
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

NCOR2_HUMAN
θ value	1.81305 (rank : 264)	NC score	0.054387 (rank : 277)
Query Neighborhood Hits	373	Target Neighborhood Hits	870	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PRGR_MOUSE
θ value	1.81305 (rank : 265)	NC score	0.006328 (rank : 402)
Query Neighborhood Hits	373	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

TEX14_MOUSE
θ value	1.81305 (rank : 266)	NC score	0.010732 (rank : 384)
Query Neighborhood Hits	373	Target Neighborhood Hits	1333	Shared Neighborhood Hits	47
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

USP9X_HUMAN
θ value	1.81305 (rank : 267)	NC score	0.013111 (rank : 369)
Query Neighborhood Hits	373	Target Neighborhood Hits	161	Shared Neighborhood Hits	12
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	1.81305 (rank : 268)	NC score	0.013020 (rank : 371)
Query Neighborhood Hits	373	Target Neighborhood Hits	171	Shared Neighborhood Hits	11
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

ZN202_HUMAN
θ value	1.81305 (rank : 269)	NC score	-0.009048 (rank : 424)
Query Neighborhood Hits	373	Target Neighborhood Hits	756	Shared Neighborhood Hits	13
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

ZN335_HUMAN
θ value	1.81305 (rank : 270)	NC score	-0.007027 (rank : 420)
Query Neighborhood Hits	373	Target Neighborhood Hits	973	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

CALR_HUMAN
θ value	2.36792 (rank : 271)	NC score	0.008786 (rank : 396)
Query Neighborhood Hits	373	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

CIC_HUMAN
θ value	2.36792 (rank : 272)	NC score	0.042299 (rank : 303)
Query Neighborhood Hits	373	Target Neighborhood Hits	992	Shared Neighborhood Hits	78
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DIDO1_HUMAN
θ value	2.36792 (rank : 273)	NC score	0.024600 (rank : 331)
Query Neighborhood Hits	373	Target Neighborhood Hits	960	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GTSE1_MOUSE
θ value	2.36792 (rank : 274)	NC score	0.027724 (rank : 324)
Query Neighborhood Hits	373	Target Neighborhood Hits	245	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

LSD1_HUMAN
θ value	2.36792 (rank : 275)	NC score	0.015701 (rank : 358)
Query Neighborhood Hits	373	Target Neighborhood Hits	455	Shared Neighborhood Hits	27
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MAP1B_HUMAN
θ value	2.36792 (rank : 276)	NC score	0.028387 (rank : 323)
Query Neighborhood Hits	373	Target Neighborhood Hits	903	Shared Neighborhood Hits	58
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NOXO1_HUMAN
θ value	2.36792 (rank : 277)	NC score	0.014699 (rank : 362)
Query Neighborhood Hits	373	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

TE2IP_MOUSE
θ value	2.36792 (rank : 278)	NC score	0.017173 (rank : 356)
Query Neighborhood Hits	373	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VL8, Q543F4, Q9JJE8, Q9JJE9	Gene names	Terf2ip, Rap1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1).

ABL2_HUMAN
θ value	3.0926 (rank : 279)	NC score	0.001090 (rank : 412)
Query Neighborhood Hits	373	Target Neighborhood Hits	1045	Shared Neighborhood Hits	27
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABLM3_MOUSE
θ value	3.0926 (rank : 280)	NC score	0.048150 (rank : 293)
Query Neighborhood Hits	373	Target Neighborhood Hits	294	Shared Neighborhood Hits	26
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ACD_HUMAN
θ value	3.0926 (rank : 281)	NC score	0.031742 (rank : 315)
Query Neighborhood Hits	373	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

CCNK_HUMAN
θ value	3.0926 (rank : 282)	NC score	0.015205 (rank : 360)
Query Neighborhood Hits	373	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

GRIN1_HUMAN
θ value	3.0926 (rank : 283)	NC score	0.032374 (rank : 314)
Query Neighborhood Hits	373	Target Neighborhood Hits	681	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

IASPP_MOUSE
θ value	3.0926 (rank : 284)	NC score	0.011915 (rank : 378)
Query Neighborhood Hits	373	Target Neighborhood Hits	1024	Shared Neighborhood Hits	50
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF4G1_HUMAN
θ value	3.0926 (rank : 285)	NC score	0.030373 (rank : 317)
Query Neighborhood Hits	373	Target Neighborhood Hits	347	Shared Neighborhood Hits	38
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MY18B_HUMAN
θ value	3.0926 (rank : 286)	NC score	0.020834 (rank : 341)
Query Neighborhood Hits	373	Target Neighborhood Hits	1299	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

PINL_HUMAN
θ value	3.0926 (rank : 287)	NC score	0.187972 (rank : 200)
Query Neighborhood Hits	373	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

PODO_HUMAN
θ value	3.0926 (rank : 288)	NC score	0.008119 (rank : 399)
Query Neighborhood Hits	373	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP85, Q8N6Q5	Gene names	NPHS2
Domain Architecture
Description	Podocin.

S13A3_MOUSE
θ value	3.0926 (rank : 289)	NC score	0.013100 (rank : 370)
Query Neighborhood Hits	373	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Y63	Gene names	Slc13a3, Nadc3, Sdct2
Domain Architecture
Description	Solute carrier family 13 member 3 (Sodium-dependent high-affinity dicarboxylate transporter 2) (Na(+)/dicarboxylate cotransporter 3) (NaDC-3) (mNaDC3).

SON_HUMAN
θ value	3.0926 (rank : 290)	NC score	0.029683 (rank : 318)
Query Neighborhood Hits	373	Target Neighborhood Hits	1568	Shared Neighborhood Hits	97
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SYNJ1_HUMAN
θ value	3.0926 (rank : 291)	NC score	0.028922 (rank : 321)
Query Neighborhood Hits	373	Target Neighborhood Hits	498	Shared Neighborhood Hits	56
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

5HT7R_HUMAN
θ value	4.03905 (rank : 292)	NC score	-0.008283 (rank : 422)
Query Neighborhood Hits	373	Target Neighborhood Hits	848	Shared Neighborhood Hits	3
SwissProt Accessions	P34969, P78336, P78372, P78516	Gene names	HTR7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

CENPC_MOUSE
θ value	4.03905 (rank : 293)	NC score	0.014478 (rank : 364)
Query Neighborhood Hits	373	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

CTRO_HUMAN
θ value	4.03905 (rank : 294)	NC score	0.016251 (rank : 357)
Query Neighborhood Hits	373	Target Neighborhood Hits	2092	Shared Neighborhood Hits	66
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CYTSA_HUMAN
θ value	4.03905 (rank : 295)	NC score	0.008865 (rank : 395)
Query Neighborhood Hits	373	Target Neighborhood Hits	1138	Shared Neighborhood Hits	42
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DMD_HUMAN
θ value	4.03905 (rank : 296)	NC score	0.025455 (rank : 328)
Query Neighborhood Hits	373	Target Neighborhood Hits	1135	Shared Neighborhood Hits	56
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	4.03905 (rank : 297)	NC score	0.023712 (rank : 333)
Query Neighborhood Hits	373	Target Neighborhood Hits	1111	Shared Neighborhood Hits	58
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

G3PT_MOUSE
θ value	4.03905 (rank : 298)	NC score	0.022668 (rank : 335)
Query Neighborhood Hits	373	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

GGA1_HUMAN
θ value	4.03905 (rank : 299)	NC score	0.009654 (rank : 392)
Query Neighborhood Hits	373	Target Neighborhood Hits	169	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

NCTR2_HUMAN
θ value	4.03905 (rank : 300)	NC score	0.014518 (rank : 363)
Query Neighborhood Hits	373	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

PRD16_HUMAN
θ value	4.03905 (rank : 301)	NC score	-0.008290 (rank : 423)
Query Neighborhood Hits	373	Target Neighborhood Hits	832	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

SDCB1_HUMAN
θ value	4.03905 (rank : 302)	NC score	0.309847 (rank : 154)
Query Neighborhood Hits	373	Target Neighborhood Hits	150	Shared Neighborhood Hits	140
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SETD8_MOUSE
θ value	4.03905 (rank : 303)	NC score	0.010612 (rank : 385)
Query Neighborhood Hits	373	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SEZ6L_HUMAN
θ value	4.03905 (rank : 304)	NC score	0.012640 (rank : 375)
Query Neighborhood Hits	373	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SPF45_HUMAN
θ value	4.03905 (rank : 305)	NC score	0.019933 (rank : 345)
Query Neighborhood Hits	373	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

VCY1_HUMAN
θ value	4.03905 (rank : 306)	NC score	0.101045 (rank : 229)
Query Neighborhood Hits	373	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

5HT7R_MOUSE
θ value	5.27518 (rank : 307)	NC score	-0.008024 (rank : 421)
Query Neighborhood Hits	373	Target Neighborhood Hits	823	Shared Neighborhood Hits	3
SwissProt Accessions	P32304	Gene names	Htr7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

ABLM3_HUMAN
θ value	5.27518 (rank : 308)	NC score	0.046938 (rank : 294)
Query Neighborhood Hits	373	Target Neighborhood Hits	293	Shared Neighborhood Hits	25
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

CELR1_MOUSE
θ value	5.27518 (rank : 309)	NC score	-0.005971 (rank : 418)
Query Neighborhood Hits	373	Target Neighborhood Hits	617	Shared Neighborhood Hits	7
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CO3_MOUSE
θ value	5.27518 (rank : 310)	NC score	0.004029 (rank : 406)
Query Neighborhood Hits	373	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	P01027, Q61370	Gene names	C3
Domain Architecture
Description	Complement C3 precursor (HSE-MSF) [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3, isoform Short; Complement C3f fragment].

DGKB_HUMAN
θ value	5.27518 (rank : 311)	NC score	0.000524 (rank : 414)
Query Neighborhood Hits	373	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

ETV6_HUMAN
θ value	5.27518 (rank : 312)	NC score	0.011458 (rank : 380)
Query Neighborhood Hits	373	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

GP137_MOUSE
θ value	5.27518 (rank : 313)	NC score	0.019413 (rank : 350)
Query Neighborhood Hits	373	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q60865, Q60758, Q61620	Gene names	M11s1, Gpiap, Gpiap1, Gpip137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI).

HGS_MOUSE
θ value	5.27518 (rank : 314)	NC score	0.019697 (rank : 347)
Query Neighborhood Hits	373	Target Neighborhood Hits	589	Shared Neighborhood Hits	54
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HRBL_MOUSE
θ value	5.27518 (rank : 315)	NC score	0.008155 (rank : 398)
Query Neighborhood Hits	373	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

KLH14_HUMAN
θ value	5.27518 (rank : 316)	NC score	-0.001004 (rank : 416)
Query Neighborhood Hits	373	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2G3	Gene names	KLHL14, KIAA1384
Domain Architecture	No domain graphic available
Description	Kelch-like protein 14.

MBD6_HUMAN
θ value	5.27518 (rank : 317)	NC score	0.036825 (rank : 308)
Query Neighborhood Hits	373	Target Neighborhood Hits	349	Shared Neighborhood Hits	38
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MTG8R_HUMAN
θ value	5.27518 (rank : 318)	NC score	0.006146 (rank : 403)
Query Neighborhood Hits	373	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

PIN1_HUMAN
θ value	5.27518 (rank : 319)	NC score	0.163705 (rank : 210)
Query Neighborhood Hits	373	Target Neighborhood Hits	59	Shared Neighborhood Hits	35
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	5.27518 (rank : 320)	NC score	0.164872 (rank : 209)
Query Neighborhood Hits	373	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PRGC1_MOUSE
θ value	5.27518 (rank : 321)	NC score	0.012895 (rank : 373)
Query Neighborhood Hits	373	Target Neighborhood Hits	238	Shared Neighborhood Hits	16
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

RHG12_HUMAN
θ value	5.27518 (rank : 322)	NC score	0.043068 (rank : 302)
Query Neighborhood Hits	373	Target Neighborhood Hits	190	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	5.27518 (rank : 323)	NC score	0.049213 (rank : 292)
Query Neighborhood Hits	373	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SMRA3_MOUSE
θ value	5.27518 (rank : 324)	NC score	0.013353 (rank : 367)
Query Neighborhood Hits	373	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TP53B_MOUSE
θ value	5.27518 (rank : 325)	NC score	0.027392 (rank : 325)
Query Neighborhood Hits	373	Target Neighborhood Hits	644	Shared Neighborhood Hits	50
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

UBP42_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.017629 (rank : 354)
Query Neighborhood Hits	373	Target Neighborhood Hits	445	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

BAT2_MOUSE
θ value	6.88961 (rank : 327)	NC score	0.043387 (rank : 301)
Query Neighborhood Hits	373	Target Neighborhood Hits	947	Shared Neighborhood Hits	94
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAC1A_HUMAN
θ value	6.88961 (rank : 328)	NC score	0.010195 (rank : 389)
Query Neighborhood Hits	373	Target Neighborhood Hits	387	Shared Neighborhood Hits	41
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CRSP2_HUMAN
θ value	6.88961 (rank : 329)	NC score	0.028632 (rank : 322)
Query Neighborhood Hits	373	Target Neighborhood Hits	380	Shared Neighborhood Hits	41
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

EPHB3_MOUSE
θ value	6.88961 (rank : 330)	NC score	0.000734 (rank : 413)
Query Neighborhood Hits	373	Target Neighborhood Hits	996	Shared Neighborhood Hits	26
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

HKR3_HUMAN
θ value	6.88961 (rank : 331)	NC score	-0.009228 (rank : 425)
Query Neighborhood Hits	373	Target Neighborhood Hits	839	Shared Neighborhood Hits	11
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).

IKBL_MOUSE
θ value	6.88961 (rank : 332)	NC score	0.007729 (rank : 400)
Query Neighborhood Hits	373	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

K1688_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.022180 (rank : 337)
Query Neighborhood Hits	373	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MLL2_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.034687 (rank : 311)
Query Neighborhood Hits	373	Target Neighborhood Hits	1788	Shared Neighborhood Hits	113
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NACAM_MOUSE
θ value	6.88961 (rank : 335)	NC score	0.053676 (rank : 278)
Query Neighborhood Hits	373	Target Neighborhood Hits	1866	Shared Neighborhood Hits	129
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_MOUSE
θ value	6.88961 (rank : 336)	NC score	0.029482 (rank : 320)
Query Neighborhood Hits	373	Target Neighborhood Hits	1076	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NUFP1_HUMAN
θ value	6.88961 (rank : 337)	NC score	0.019063 (rank : 351)
Query Neighborhood Hits	373	Target Neighborhood Hits	193	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PCOC1_HUMAN
θ value	6.88961 (rank : 338)	NC score	0.002237 (rank : 409)
Query Neighborhood Hits	373	Target Neighborhood Hits	146	Shared Neighborhood Hits	10
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

RP1L1_HUMAN
θ value	6.88961 (rank : 339)	NC score	0.033407 (rank : 313)
Query Neighborhood Hits	373	Target Neighborhood Hits	1072	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SMOO_HUMAN
θ value	6.88961 (rank : 340)	NC score	0.026952 (rank : 326)
Query Neighborhood Hits	373	Target Neighborhood Hits	391	Shared Neighborhood Hits	51
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TARSH_HUMAN
θ value	6.88961 (rank : 341)	NC score	0.037150 (rank : 307)
Query Neighborhood Hits	373	Target Neighborhood Hits	768	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TRI32_MOUSE
θ value	6.88961 (rank : 342)	NC score	0.003198 (rank : 407)
Query Neighborhood Hits	373	Target Neighborhood Hits	271	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TXND2_HUMAN
θ value	6.88961 (rank : 343)	NC score	0.040714 (rank : 304)
Query Neighborhood Hits	373	Target Neighborhood Hits	793	Shared Neighborhood Hits	65
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UTRO_HUMAN
θ value	6.88961 (rank : 344)	NC score	0.020687 (rank : 343)
Query Neighborhood Hits	373	Target Neighborhood Hits	960	Shared Neighborhood Hits	54
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

ZBTB9_HUMAN
θ value	6.88961 (rank : 345)	NC score	-0.006255 (rank : 419)
Query Neighborhood Hits	373	Target Neighborhood Hits	764	Shared Neighborhood Hits	10
SwissProt Accessions	Q96C00	Gene names	ZBTB9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

BAT2_HUMAN
θ value	8.99809 (rank : 346)	NC score	0.057926 (rank : 268)
Query Neighborhood Hits	373	Target Neighborhood Hits	931	Shared Neighborhood Hits	100
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL7A_MOUSE
θ value	8.99809 (rank : 347)	NC score	0.012686 (rank : 374)
Query Neighborhood Hits	373	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

CLIC6_HUMAN
θ value	8.99809 (rank : 348)	NC score	0.013317 (rank : 368)
Query Neighborhood Hits	373	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CLSPN_MOUSE
θ value	8.99809 (rank : 349)	NC score	0.014344 (rank : 365)
Query Neighborhood Hits	373	Target Neighborhood Hits	292	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

CO039_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.025080 (rank : 329)
Query Neighborhood Hits	373	Target Neighborhood Hits	264	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CUTL1_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.010369 (rank : 386)
Query Neighborhood Hits	373	Target Neighborhood Hits	1620	Shared Neighborhood Hits	75
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CYTSA_MOUSE
θ value	8.99809 (rank : 352)	NC score	0.006028 (rank : 404)
Query Neighborhood Hits	373	Target Neighborhood Hits	1104	Shared Neighborhood Hits	36
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

GLE1_MOUSE
θ value	8.99809 (rank : 353)	NC score	0.006730 (rank : 401)
Query Neighborhood Hits	373	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

HCFC1_HUMAN
θ value	8.99809 (rank : 354)	NC score	0.013001 (rank : 372)
Query Neighborhood Hits	373	Target Neighborhood Hits	331	Shared Neighborhood Hits	30
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_MOUSE
θ value	8.99809 (rank : 355)	NC score	0.011665 (rank : 379)
Query Neighborhood Hits	373	Target Neighborhood Hits	348	Shared Neighborhood Hits	30
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

IER5_MOUSE
θ value	8.99809 (rank : 356)	NC score	0.011373 (rank : 381)
Query Neighborhood Hits	373	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

INVS_HUMAN
θ value	8.99809 (rank : 357)	NC score	-0.000260 (rank : 415)
Query Neighborhood Hits	373	Target Neighborhood Hits	455	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

IQEC2_HUMAN
θ value	8.99809 (rank : 358)	NC score	0.011128 (rank : 382)
Query Neighborhood Hits	373	Target Neighborhood Hits	403	Shared Neighborhood Hits	39
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	8.99809 (rank : 359)	NC score	0.012449 (rank : 376)
Query Neighborhood Hits	373	Target Neighborhood Hits	417	Shared Neighborhood Hits	43
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

JPH2_HUMAN
θ value	8.99809 (rank : 360)	NC score	0.017606 (rank : 355)
Query Neighborhood Hits	373	Target Neighborhood Hits	639	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KCNQ1_HUMAN
θ value	8.99809 (rank : 361)	NC score	0.001926 (rank : 410)
Query Neighborhood Hits	373	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

LEUK_MOUSE
θ value	8.99809 (rank : 362)	NC score	0.022807 (rank : 334)
Query Neighborhood Hits	373	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MARCS_HUMAN
θ value	8.99809 (rank : 363)	NC score	0.050043 (rank : 291)
Query Neighborhood Hits	373	Target Neighborhood Hits	204	Shared Neighborhood Hits	31
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MYO5A_HUMAN
θ value	8.99809 (rank : 364)	NC score	0.009223 (rank : 393)
Query Neighborhood Hits	373	Target Neighborhood Hits	1092	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NCOA6_HUMAN
θ value	8.99809 (rank : 365)	NC score	0.034791 (rank : 310)
Query Neighborhood Hits	373	Target Neighborhood Hits	1202	Shared Neighborhood Hits	94
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NOP14_HUMAN
θ value	8.99809 (rank : 366)	NC score	0.018773 (rank : 352)
Query Neighborhood Hits	373	Target Neighborhood Hits	573	Shared Neighborhood Hits	26
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NOTC1_MOUSE
θ value	8.99809 (rank : 367)	NC score	-0.005445 (rank : 417)
Query Neighborhood Hits	373	Target Neighborhood Hits	916	Shared Neighborhood Hits	21
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NUMA1_HUMAN
θ value	8.99809 (rank : 368)	NC score	0.009720 (rank : 391)
Query Neighborhood Hits	373	Target Neighborhood Hits	1523	Shared Neighborhood Hits	56
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PRAX_MOUSE
θ value	8.99809 (rank : 369)	NC score	0.090149 (rank : 238)
Query Neighborhood Hits	373	Target Neighborhood Hits	199	Shared Neighborhood Hits	54
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SPF45_MOUSE
θ value	8.99809 (rank : 370)	NC score	0.010797 (rank : 383)
Query Neighborhood Hits	373	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q8JZX4, O75939	Gene names	Rbm17, Spf45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

THAP7_MOUSE
θ value	8.99809 (rank : 371)	NC score	0.013628 (rank : 366)
Query Neighborhood Hits	373	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

TXLNA_HUMAN
θ value	8.99809 (rank : 372)	NC score	0.010313 (rank : 387)
Query Neighborhood Hits	373	Target Neighborhood Hits	982	Shared Neighborhood Hits	49
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

YLPM1_HUMAN
θ value	8.99809 (rank : 373)	NC score	0.039798 (rank : 305)
Query Neighborhood Hits	373	Target Neighborhood Hits	670	Shared Neighborhood Hits	67
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

APBB2_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.057139 (rank : 270)
Query Neighborhood Hits	373	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

CAR11_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.058563 (rank : 266)
Query Neighborhood Hits	373	Target Neighborhood Hits	690	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CAR14_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.051944 (rank : 284)
Query Neighborhood Hits	373	Target Neighborhood Hits	449	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

EDD1_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.099229 (rank : 231)
Query Neighborhood Hits	373	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.099045 (rank : 232)
Query Neighborhood Hits	373	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

GAS7_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.092929 (rank : 236)
Query Neighborhood Hits	373	Target Neighborhood Hits	258	Shared Neighborhood Hits	43
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.088082 (rank : 240)
Query Neighborhood Hits	373	Target Neighborhood Hits	259	Shared Neighborhood Hits	41
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

HECD1_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.086013 (rank : 241)
Query Neighborhood Hits	373	Target Neighborhood Hits	371	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HECD2_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.142615 (rank : 217)
Query Neighborhood Hits	373	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.143437 (rank : 216)
Query Neighborhood Hits	373	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD3_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.098255 (rank : 234)
Query Neighborhood Hits	373	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.100018 (rank : 230)
Query Neighborhood Hits	373	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC2_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.092341 (rank : 237)
Query Neighborhood Hits	373	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.093502 (rank : 235)
Query Neighborhood Hits	373	Target Neighborhood Hits	167	Shared Neighborhood Hits	23
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC3_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.114998 (rank : 227)
Query Neighborhood Hits	373	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.118389 (rank : 226)
Query Neighborhood Hits	373	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HTRA3_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.056542 (rank : 272)
Query Neighborhood Hits	373	Target Neighborhood Hits	152	Shared Neighborhood Hits	59
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.062148 (rank : 260)
Query Neighborhood Hits	373	Target Neighborhood Hits	156	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HUWE1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.152270 (rank : 213)
Query Neighborhood Hits	373	Target Neighborhood Hits	443	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.153519 (rank : 212)
Query Neighborhood Hits	373	Target Neighborhood Hits	406	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

K0317_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.150260 (rank : 214)
Query Neighborhood Hits	373	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.150207 (rank : 215)
Query Neighborhood Hits	373	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

LMO7_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.078623 (rank : 249)
Query Neighborhood Hits	373	Target Neighborhood Hits	507	Shared Neighborhood Hits	67
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LPXN_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.052874 (rank : 280)
Query Neighborhood Hits	373	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	O60711	Gene names	LPXN, LDLP
Domain Architecture
Description	Leupaxin.

LPXN_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.050772 (rank : 286)
Query Neighborhood Hits	373	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

PAXI_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.050122 (rank : 290)
Query Neighborhood Hits	373	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

PAXI_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.050178 (rank : 288)
Query Neighborhood Hits	373	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

PCLO_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.061089 (rank : 262)
Query Neighborhood Hits	373	Target Neighborhood Hits	2046	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PDZD8_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.089410 (rank : 239)
Query Neighborhood Hits	373	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PINC_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.050223 (rank : 287)
Query Neighborhood Hits	373	Target Neighborhood Hits	231	Shared Neighborhood Hits	20
SwissProt Accessions	P48059, Q53TE0, Q9BS44	Gene names	LIMS1
Domain Architecture
Description	Protein PINCH (Particularly interesting new Cys-His protein) (LIM and senescent cell antigen-like domains 1) (NY-REN-48 antigen).

PRAX_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.064507 (rank : 257)
Query Neighborhood Hits	373	Target Neighborhood Hits	215	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRP40_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.064994 (rank : 256)
Query Neighborhood Hits	373	Target Neighborhood Hits	442	Shared Neighborhood Hits	48
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.064347 (rank : 258)
Query Neighborhood Hits	373	Target Neighborhood Hits	447	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PTN23_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.052087 (rank : 283)
Query Neighborhood Hits	373	Target Neighborhood Hits	726	Shared Neighborhood Hits	69
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RAIN_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.056566 (rank : 271)
Query Neighborhood Hits	373	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RAIN_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.055738 (rank : 273)
Query Neighborhood Hits	373	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q3U0S6, Q6GQW4	Gene names	Rasip1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RHPN2_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.076464 (rank : 251)
Query Neighborhood Hits	373	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RNF41_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.060489 (rank : 263)
Query Neighborhood Hits	373	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.060456 (rank : 264)
Query Neighborhood Hits	373	Target Neighborhood Hits	224	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SETD2_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.061422 (rank : 261)
Query Neighborhood Hits	373	Target Neighborhood Hits	412	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SRRM1_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.054923 (rank : 275)
Query Neighborhood Hits	373	Target Neighborhood Hits	690	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.063148 (rank : 259)
Query Neighborhood Hits	373	Target Neighborhood Hits	966	Shared Neighborhood Hits	100
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.075652 (rank : 252)
Query Neighborhood Hits	373	Target Neighborhood Hits	1296	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.067809 (rank : 255)
Query Neighborhood Hits	373	Target Neighborhood Hits	1470	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TIAM1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.074688 (rank : 253)
Query Neighborhood Hits	373	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.050150 (rank : 289)
Query Neighborhood Hits	373	Target Neighborhood Hits	205	Shared Neighborhood Hits	51
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TRIPC_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.139603 (rank : 218)
Query Neighborhood Hits	373	Target Neighborhood Hits	319	Shared Neighborhood Hits	32
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

UBE3A_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.138845 (rank : 219)
Query Neighborhood Hits	373	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.136992 (rank : 221)
Query Neighborhood Hits	373	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.137198 (rank : 220)
Query Neighborhood Hits	373	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.136901 (rank : 222)
Query Neighborhood Hits	373	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

WWC3_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.080919 (rank : 245)
Query Neighborhood Hits	373	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

Hits sorted by NC score

MAGI2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	373	Target Neighborhood Hits	373	Shared Neighborhood Hits	373
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
NC score	0.987701 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	373	Target Neighborhood Hits	370	Shared Neighborhood Hits	288
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI1_HUMAN
NC score	0.959058 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	373	Target Neighborhood Hits	388	Shared Neighborhood Hits	245
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.955359 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	373	Target Neighborhood Hits	403	Shared Neighborhood Hits	239
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MPDZ_HUMAN
NC score	0.701954 (rank : 5)	θ value	1.09232e-21 (rank : 5)
Query Neighborhood Hits	373	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

INADL_MOUSE
NC score	0.695600 (rank : 6)	θ value	1.63225e-17 (rank : 8)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	196
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

MPDZ_MOUSE
NC score	0.695059 (rank : 7)	θ value	4.02038e-16 (rank : 12)
Query Neighborhood Hits	373	Target Neighborhood Hits	298	Shared Neighborhood Hits	196
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

SYJ2B_HUMAN
NC score	0.694113 (rank : 8)	θ value	2.36244e-08 (rank : 70)
Query Neighborhood Hits	373	Target Neighborhood Hits	162	Shared Neighborhood Hits	159
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

LIN7B_HUMAN
NC score	0.692594 (rank : 9)	θ value	2.52405e-10 (rank : 46)
Query Neighborhood Hits	373	Target Neighborhood Hits	200	Shared Neighborhood Hits	187
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.691854 (rank : 10)	θ value	6.64225e-11 (rank : 34)
Query Neighborhood Hits	373	Target Neighborhood Hits	200	Shared Neighborhood Hits	187
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

INADL_HUMAN
NC score	0.691816 (rank : 11)	θ value	3.28887e-18 (rank : 7)
Query Neighborhood Hits	373	Target Neighborhood Hits	260	Shared Neighborhood Hits	192
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

LIN7C_HUMAN
NC score	0.691240 (rank : 12)	θ value	1.47974e-10 (rank : 38)
Query Neighborhood Hits	373	Target Neighborhood Hits	198	Shared Neighborhood Hits	187
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.691240 (rank : 13)	θ value	1.47974e-10 (rank : 39)
Query Neighborhood Hits	373	Target Neighborhood Hits	198	Shared Neighborhood Hits	187
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7A_MOUSE
NC score	0.686027 (rank : 14)	θ value	9.59137e-10 (rank : 52)
Query Neighborhood Hits	373	Target Neighborhood Hits	193	Shared Neighborhood Hits	186
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7A_HUMAN
NC score	0.685878 (rank : 15)	θ value	9.59137e-10 (rank : 51)
Query Neighborhood Hits	373	Target Neighborhood Hits	193	Shared Neighborhood Hits	186
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

PDZD7_HUMAN
NC score	0.676599 (rank : 16)	θ value	2.79066e-09 (rank : 57)
Query Neighborhood Hits	373	Target Neighborhood Hits	181	Shared Neighborhood Hits	170
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PARD3_MOUSE
NC score	0.641784 (rank : 17)	θ value	8.38298e-14 (rank : 14)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	164
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PARD3_HUMAN
NC score	0.640396 (rank : 18)	θ value	1.68911e-14 (rank : 13)
Query Neighborhood Hits	373	Target Neighborhood Hits	312	Shared Neighborhood Hits	168
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

USH1C_HUMAN
NC score	0.639281 (rank : 19)	θ value	7.59969e-07 (rank : 89)
Query Neighborhood Hits	373	Target Neighborhood Hits	327	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

GRIP2_HUMAN
NC score	0.635188 (rank : 20)	θ value	3.64472e-09 (rank : 58)
Query Neighborhood Hits	373	Target Neighborhood Hits	256	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

WHRN_MOUSE
NC score	0.635082 (rank : 21)	θ value	2.36244e-08 (rank : 71)
Query Neighborhood Hits	373	Target Neighborhood Hits	412	Shared Neighborhood Hits	200
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WHRN_HUMAN
NC score	0.632943 (rank : 22)	θ value	1.80886e-08 (rank : 69)
Query Neighborhood Hits	373	Target Neighborhood Hits	325	Shared Neighborhood Hits	193
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

PAR3L_HUMAN
NC score	0.628727 (rank : 23)	θ value	1.9326e-10 (rank : 44)
Query Neighborhood Hits	373	Target Neighborhood Hits	297	Shared Neighborhood Hits	160
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDZD1_MOUSE
NC score	0.628424 (rank : 24)	θ value	7.84624e-12 (rank : 25)
Query Neighborhood Hits	373	Target Neighborhood Hits	191	Shared Neighborhood Hits	156
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

GRIP1_HUMAN
NC score	0.626899 (rank : 25)	θ value	1.53129e-07 (rank : 81)
Query Neighborhood Hits	373	Target Neighborhood Hits	231	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
NC score	0.622027 (rank : 26)	θ value	1.99992e-07 (rank : 82)
Query Neighborhood Hits	373	Target Neighborhood Hits	241	Shared Neighborhood Hits	193
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

DLG4_MOUSE
NC score	0.614718 (rank : 27)	θ value	7.84624e-12 (rank : 24)
Query Neighborhood Hits	373	Target Neighborhood Hits	282	Shared Neighborhood Hits	187
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

NHRF2_HUMAN
NC score	0.614601 (rank : 28)	θ value	1.25267e-09 (rank : 54)
Query Neighborhood Hits	373	Target Neighborhood Hits	197	Shared Neighborhood Hits	165
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PDZD1_HUMAN
NC score	0.614558 (rank : 29)	θ value	5.81887e-07 (rank : 87)
Query Neighborhood Hits	373	Target Neighborhood Hits	190	Shared Neighborhood Hits	153
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

DLG4_HUMAN
NC score	0.613825 (rank : 30)	θ value	6.00763e-12 (rank : 22)
Query Neighborhood Hits	373	Target Neighborhood Hits	286	Shared Neighborhood Hits	185
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PDZ11_HUMAN
NC score	0.611436 (rank : 31)	θ value	3.19293e-05 (rank : 121)
Query Neighborhood Hits	373	Target Neighborhood Hits	160	Shared Neighborhood Hits	145
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZD2_HUMAN
NC score	0.609937 (rank : 32)	θ value	1.02475e-11 (rank : 26)
Query Neighborhood Hits	373	Target Neighborhood Hits	772	Shared Neighborhood Hits	222
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

DLG3_MOUSE
NC score	0.609404 (rank : 33)	θ value	3.52202e-12 (rank : 20)
Query Neighborhood Hits	373	Target Neighborhood Hits	274	Shared Neighborhood Hits	182
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.607831 (rank : 34)	θ value	4.59992e-12 (rank : 21)
Query Neighborhood Hits	373	Target Neighborhood Hits	269	Shared Neighborhood Hits	182
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

PDZ11_MOUSE
NC score	0.607028 (rank : 35)	θ value	3.19293e-05 (rank : 122)
Query Neighborhood Hits	373	Target Neighborhood Hits	154	Shared Neighborhood Hits	138
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

NHERF_MOUSE
NC score	0.606539 (rank : 36)	θ value	3.08544e-08 (rank : 72)
Query Neighborhood Hits	373	Target Neighborhood Hits	195	Shared Neighborhood Hits	159
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_MOUSE
NC score	0.605985 (rank : 37)	θ value	1.25267e-09 (rank : 55)
Query Neighborhood Hits	373	Target Neighborhood Hits	194	Shared Neighborhood Hits	166
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

DLG2_HUMAN
NC score	0.601115 (rank : 38)	θ value	4.16044e-13 (rank : 17)
Query Neighborhood Hits	373	Target Neighborhood Hits	279	Shared Neighborhood Hits	183
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG1_HUMAN
NC score	0.599611 (rank : 39)	θ value	2.0648e-12 (rank : 18)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	180
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
NC score	0.598061 (rank : 40)	θ value	2.69671e-12 (rank : 19)
Query Neighborhood Hits	373	Target Neighborhood Hits	285	Shared Neighborhood Hits	180
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG2_MOUSE
NC score	0.597871 (rank : 41)	θ value	1.47974e-10 (rank : 37)
Query Neighborhood Hits	373	Target Neighborhood Hits	271	Shared Neighborhood Hits	181
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

USH1C_MOUSE
NC score	0.594619 (rank : 42)	θ value	4.92598e-06 (rank : 105)
Query Neighborhood Hits	373	Target Neighborhood Hits	557	Shared Neighborhood Hits	207
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

GOPC_MOUSE
NC score	0.594548 (rank : 43)	θ value	1.09739e-05 (rank : 110)
Query Neighborhood Hits	373	Target Neighborhood Hits	323	Shared Neighborhood Hits	174
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LNX2_HUMAN
NC score	0.594385 (rank : 44)	θ value	6.00763e-12 (rank : 23)
Query Neighborhood Hits	373	Target Neighborhood Hits	389	Shared Neighborhood Hits	181
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
NC score	0.594273 (rank : 45)	θ value	1.47974e-10 (rank : 40)
Query Neighborhood Hits	373	Target Neighborhood Hits	407	Shared Neighborhood Hits	183
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

SNTG2_HUMAN
NC score	0.590019 (rank : 46)	θ value	1.17247e-07 (rank : 80)
Query Neighborhood Hits	373	Target Neighborhood Hits	191	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

NHERF_HUMAN
NC score	0.590012 (rank : 47)	θ value	1.69304e-06 (rank : 95)
Query Neighborhood Hits	373	Target Neighborhood Hits	190	Shared Neighborhood Hits	155
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

IL16_HUMAN
NC score	0.588434 (rank : 48)	θ value	8.40245e-06 (rank : 107)
Query Neighborhood Hits	373	Target Neighborhood Hits	207	Shared Neighborhood Hits	150
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LNX1_HUMAN
NC score	0.585982 (rank : 49)	θ value	2.52405e-10 (rank : 47)
Query Neighborhood Hits	373	Target Neighborhood Hits	379	Shared Neighborhood Hits	173
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

GOPC_HUMAN
NC score	0.585332 (rank : 50)	θ value	1.09739e-05 (rank : 109)
Query Neighborhood Hits	373	Target Neighborhood Hits	377	Shared Neighborhood Hits	174
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

LNX1_MOUSE
NC score	0.585205 (rank : 51)	θ value	6.21693e-09 (rank : 61)
Query Neighborhood Hits	373	Target Neighborhood Hits	377	Shared Neighborhood Hits	180
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

SNTG1_HUMAN
NC score	0.567985 (rank : 52)	θ value	3.64472e-09 (rank : 59)
Query Neighborhood Hits	373	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_MOUSE
NC score	0.566824 (rank : 53)	θ value	6.21693e-09 (rank : 62)
Query Neighborhood Hits	373	Target Neighborhood Hits	179	Shared Neighborhood Hits	173
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDZD3_HUMAN
NC score	0.564412 (rank : 54)	θ value	1.69304e-06 (rank : 96)
Query Neighborhood Hits	373	Target Neighborhood Hits	180	Shared Neighborhood Hits	158
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

ZO3_MOUSE
NC score	0.562004 (rank : 55)	θ value	2.98157e-11 (rank : 30)
Query Neighborhood Hits	373	Target Neighborhood Hits	224	Shared Neighborhood Hits	177
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNTB2_HUMAN
NC score	0.559397 (rank : 56)	θ value	3.08544e-08 (rank : 73)
Query Neighborhood Hits	373	Target Neighborhood Hits	180	Shared Neighborhood Hits	163
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG2_MOUSE
NC score	0.559177 (rank : 57)	θ value	2.61198e-07 (rank : 85)
Query Neighborhood Hits	373	Target Neighborhood Hits	176	Shared Neighborhood Hits	171
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTB2_MOUSE
NC score	0.558895 (rank : 58)	θ value	8.97725e-08 (rank : 77)
Query Neighborhood Hits	373	Target Neighborhood Hits	181	Shared Neighborhood Hits	164
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

TX1B3_HUMAN
NC score	0.556025 (rank : 59)	θ value	0.00509761 (rank : 170)
Query Neighborhood Hits	373	Target Neighborhood Hits	161	Shared Neighborhood Hits	153
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

ZO3_HUMAN
NC score	0.555400 (rank : 60)	θ value	2.28291e-11 (rank : 29)
Query Neighborhood Hits	373	Target Neighborhood Hits	219	Shared Neighborhood Hits	170
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNTA1_HUMAN
NC score	0.554900 (rank : 61)	θ value	1.17247e-07 (rank : 78)
Query Neighborhood Hits	373	Target Neighborhood Hits	186	Shared Neighborhood Hits	173
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

IL16_MOUSE
NC score	0.553459 (rank : 62)	θ value	0.00035302 (rank : 145)
Query Neighborhood Hits	373	Target Neighborhood Hits	189	Shared Neighborhood Hits	143
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

TX1B3_MOUSE
NC score	0.552210 (rank : 63)	θ value	0.00509761 (rank : 171)
Query Neighborhood Hits	373	Target Neighborhood Hits	158	Shared Neighborhood Hits	150
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

SNTA1_MOUSE
NC score	0.545991 (rank : 64)	θ value	1.17247e-07 (rank : 79)
Query Neighborhood Hits	373	Target Neighborhood Hits	170	Shared Neighborhood Hits	163
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PDZD3_MOUSE
NC score	0.535989 (rank : 65)	θ value	2.44474e-05 (rank : 119)
Query Neighborhood Hits	373	Target Neighborhood Hits	171	Shared Neighborhood Hits	155
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

K1849_HUMAN
NC score	0.520490 (rank : 66)	θ value	8.67504e-11 (rank : 36)
Query Neighborhood Hits	373	Target Neighborhood Hits	220	Shared Neighborhood Hits	151
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SNTB1_HUMAN
NC score	0.519924 (rank : 67)	θ value	1.09739e-05 (rank : 112)
Query Neighborhood Hits	373	Target Neighborhood Hits	157	Shared Neighborhood Hits	152
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.516424 (rank : 68)	θ value	1.09739e-05 (rank : 113)
Query Neighborhood Hits	373	Target Neighborhood Hits	160	Shared Neighborhood Hits	151
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PZRN4_HUMAN
NC score	0.507850 (rank : 69)	θ value	2.28291e-11 (rank : 28)
Query Neighborhood Hits	373	Target Neighborhood Hits	438	Shared Neighborhood Hits	156
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZO1_MOUSE
NC score	0.503015 (rank : 70)	θ value	1.69304e-06 (rank : 97)
Query Neighborhood Hits	373	Target Neighborhood Hits	453	Shared Neighborhood Hits	188
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

K1849_MOUSE
NC score	0.500265 (rank : 71)	θ value	1.33837e-11 (rank : 27)
Query Neighborhood Hits	373	Target Neighborhood Hits	335	Shared Neighborhood Hits	153
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZO1_HUMAN
NC score	0.497904 (rank : 72)	θ value	2.61198e-07 (rank : 86)
Query Neighborhood Hits	373	Target Neighborhood Hits	474	Shared Neighborhood Hits	184
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
NC score	0.483154 (rank : 73)	θ value	9.29e-05 (rank : 131)
Query Neighborhood Hits	373	Target Neighborhood Hits	289	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
NC score	0.479695 (rank : 74)	θ value	9.29e-05 (rank : 132)
Query Neighborhood Hits	373	Target Neighborhood Hits	296	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PZRN3_MOUSE
NC score	0.479476 (rank : 75)	θ value	5.81887e-07 (rank : 88)
Query Neighborhood Hits	373	Target Neighborhood Hits	447	Shared Neighborhood Hits	153
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.477086 (rank : 76)	θ value	6.87365e-08 (rank : 75)
Query Neighborhood Hits	373	Target Neighborhood Hits	461	Shared Neighborhood Hits	155
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PDLI2_HUMAN
NC score	0.471035 (rank : 77)	θ value	2.61198e-07 (rank : 84)
Query Neighborhood Hits	373	Target Neighborhood Hits	245	Shared Neighborhood Hits	132
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

SAV1_MOUSE
NC score	0.461672 (rank : 78)	θ value	1.09485e-13 (rank : 15)
Query Neighborhood Hits	373	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SAV1_HUMAN
NC score	0.461489 (rank : 79)	θ value	2.43908e-13 (rank : 16)
Query Neighborhood Hits	373	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

PDLI2_MOUSE
NC score	0.450836 (rank : 80)	θ value	3.77169e-06 (rank : 100)
Query Neighborhood Hits	373	Target Neighborhood Hits	220	Shared Neighborhood Hits	125
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

LAP4_HUMAN
NC score	0.430366 (rank : 81)	θ value	4.30538e-10 (rank : 48)
Query Neighborhood Hits	373	Target Neighborhood Hits	608	Shared Neighborhood Hits	208
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

APBA3_HUMAN
NC score	0.429199 (rank : 82)	θ value	4.92598e-06 (rank : 102)
Query Neighborhood Hits	373	Target Neighborhood Hits	201	Shared Neighborhood Hits	143
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
NC score	0.424595 (rank : 83)	θ value	8.97725e-08 (rank : 76)
Query Neighborhood Hits	373	Target Neighborhood Hits	174	Shared Neighborhood Hits	136
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA1_HUMAN
NC score	0.422477 (rank : 84)	θ value	2.44474e-05 (rank : 116)
Query Neighborhood Hits	373	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

LAP4_MOUSE
NC score	0.421635 (rank : 85)	θ value	6.21693e-09 (rank : 60)
Query Neighborhood Hits	373	Target Neighborhood Hits	590	Shared Neighborhood Hits	203
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

STXB4_HUMAN
NC score	0.418466 (rank : 86)	θ value	5.44631e-05 (rank : 127)
Query Neighborhood Hits	373	Target Neighborhood Hits	616	Shared Neighborhood Hits	142
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

YAP1_MOUSE
NC score	0.415240 (rank : 87)	θ value	1.47974e-10 (rank : 43)
Query Neighborhood Hits	373	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

GRASP_HUMAN
NC score	0.414725 (rank : 88)	θ value	0.0148317 (rank : 184)
Query Neighborhood Hits	373	Target Neighborhood Hits	147	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.413980 (rank : 89)	θ value	0.0252991 (rank : 194)
Query Neighborhood Hits	373	Target Neighborhood Hits	131	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

STXB4_MOUSE
NC score	0.412424 (rank : 90)	θ value	0.00020696 (rank : 137)
Query Neighborhood Hits	373	Target Neighborhood Hits	629	Shared Neighborhood Hits	139
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYP2L_HUMAN
NC score	0.411963 (rank : 91)	θ value	2.44474e-05 (rank : 120)
Query Neighborhood Hits	373	Target Neighborhood Hits	400	Shared Neighborhood Hits	154
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PTN13_HUMAN
NC score	0.410734 (rank : 92)	θ value	2.97466e-19 (rank : 6)
Query Neighborhood Hits	373	Target Neighborhood Hits	471	Shared Neighborhood Hits	190
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PSCBP_MOUSE
NC score	0.410378 (rank : 93)	θ value	0.00102713 (rank : 158)
Query Neighborhood Hits	373	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

MPP4_HUMAN
NC score	0.407778 (rank : 94)	θ value	0.0193708 (rank : 191)
Query Neighborhood Hits	373	Target Neighborhood Hits	205	Shared Neighborhood Hits	142
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PICK1_MOUSE
NC score	0.405656 (rank : 95)	θ value	0.00035302 (rank : 146)
Query Neighborhood Hits	373	Target Neighborhood Hits	131	Shared Neighborhood Hits	122
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
NC score	0.404350 (rank : 96)	θ value	0.000461057 (rank : 150)
Query Neighborhood Hits	373	Target Neighborhood Hits	132	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

APBA2_HUMAN
NC score	0.401828 (rank : 97)	θ value	0.000270298 (rank : 138)
Query Neighborhood Hits	373	Target Neighborhood Hits	220	Shared Neighborhood Hits	147
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

MPP3_MOUSE
NC score	0.401410 (rank : 98)	θ value	0.000121331 (rank : 133)
Query Neighborhood Hits	373	Target Neighborhood Hits	165	Shared Neighborhood Hits	134
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

APBA2_MOUSE
NC score	0.401259 (rank : 99)	θ value	0.000270298 (rank : 139)
Query Neighborhood Hits	373	Target Neighborhood Hits	219	Shared Neighborhood Hits	147
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

WWC1_HUMAN
NC score	0.401100 (rank : 100)	θ value	1.058e-16 (rank : 10)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

PTN13_MOUSE
NC score	0.400184 (rank : 101)	θ value	2.7842e-17 (rank : 9)
Query Neighborhood Hits	373	Target Neighborhood Hits	426	Shared Neighborhood Hits	190
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

WWC1_MOUSE
NC score	0.399147 (rank : 102)	θ value	1.058e-16 (rank : 11)
Query Neighborhood Hits	373	Target Neighborhood Hits	290	Shared Neighborhood Hits	41
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

AFAD_HUMAN
NC score	0.397620 (rank : 103)	θ value	0.0113563 (rank : 179)
Query Neighborhood Hits	373	Target Neighborhood Hits	689	Shared Neighborhood Hits	149
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

MPP3_HUMAN
NC score	0.395780 (rank : 104)	θ value	0.000461057 (rank : 149)
Query Neighborhood Hits	373	Target Neighborhood Hits	171	Shared Neighborhood Hits	134
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP5_HUMAN
NC score	0.395558 (rank : 105)	θ value	0.00134147 (rank : 159)
Query Neighborhood Hits	373	Target Neighborhood Hits	231	Shared Neighborhood Hits	141
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

PSCBP_HUMAN
NC score	0.394991 (rank : 106)	θ value	0.000786445 (rank : 155)
Query Neighborhood Hits	373	Target Neighborhood Hits	123	Shared Neighborhood Hits	113
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

MPP5_MOUSE
NC score	0.393859 (rank : 107)	θ value	0.00175202 (rank : 162)
Query Neighborhood Hits	373	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

NEB1_HUMAN
NC score	0.392947 (rank : 108)	θ value	2.21117e-06 (rank : 98)
Query Neighborhood Hits	373	Target Neighborhood Hits	829	Shared Neighborhood Hits	166
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SYNP2_MOUSE
NC score	0.381994 (rank : 109)	θ value	4.92598e-06 (rank : 104)
Query Neighborhood Hits	373	Target Neighborhood Hits	252	Shared Neighborhood Hits	130
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

MPP4_MOUSE
NC score	0.371418 (rank : 110)	θ value	0.125558 (rank : 215)
Query Neighborhood Hits	373	Target Neighborhood Hits	188	Shared Neighborhood Hits	123
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

EM55_HUMAN
NC score	0.368909 (rank : 111)	θ value	0.00175202 (rank : 161)
Query Neighborhood Hits	373	Target Neighborhood Hits	228	Shared Neighborhood Hits	130
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

NEB2_HUMAN
NC score	0.368328 (rank : 112)	θ value	1.29631e-06 (rank : 91)
Query Neighborhood Hits	373	Target Neighborhood Hits	883	Shared Neighborhood Hits	146
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.366005 (rank : 113)	θ value	1.29631e-06 (rank : 92)
Query Neighborhood Hits	373	Target Neighborhood Hits	889	Shared Neighborhood Hits	150
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

EM55_MOUSE
NC score	0.364225 (rank : 114)	θ value	0.00228821 (rank : 164)
Query Neighborhood Hits	373	Target Neighborhood Hits	221	Shared Neighborhood Hits	128
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

DLG5_HUMAN
NC score	0.360508 (rank : 115)	θ value	0.0148317 (rank : 183)
Query Neighborhood Hits	373	Target Neighborhood Hits	1088	Shared Neighborhood Hits	199
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PDZK4_HUMAN
NC score	0.359090 (rank : 116)	θ value	0.0961366 (rank : 211)
Query Neighborhood Hits	373	Target Neighborhood Hits	165	Shared Neighborhood Hits	116
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

RHPN1_MOUSE
NC score	0.358708 (rank : 117)	θ value	0.00134147 (rank : 160)
Query Neighborhood Hits	373	Target Neighborhood Hits	154	Shared Neighborhood Hits	129
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PDZK4_MOUSE
NC score	0.356369 (rank : 118)	θ value	0.0431538 (rank : 202)
Query Neighborhood Hits	373	Target Neighborhood Hits	165	Shared Neighborhood Hits	121
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SYP2L_MOUSE
NC score	0.348161 (rank : 119)	θ value	1.87187e-05 (rank : 114)
Query Neighborhood Hits	373	Target Neighborhood Hits	289	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PAR6G_MOUSE
NC score	0.343523 (rank : 120)	θ value	0.00390308 (rank : 169)
Query Neighborhood Hits	373	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

DVL3_MOUSE
NC score	0.343158 (rank : 121)	θ value	0.0193708 (rank : 188)
Query Neighborhood Hits	373	Target Neighborhood Hits	198	Shared Neighborhood Hits	127
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

SYNP2_HUMAN
NC score	0.343054 (rank : 122)	θ value	1.29631e-06 (rank : 93)
Query Neighborhood Hits	373	Target Neighborhood Hits	323	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

DVL3_HUMAN
NC score	0.342482 (rank : 123)	θ value	0.0193708 (rank : 187)
Query Neighborhood Hits	373	Target Neighborhood Hits	194	Shared Neighborhood Hits	124
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

SHAN2_HUMAN
NC score	0.341830 (rank : 124)	θ value	7.1131e-05 (rank : 128)
Query Neighborhood Hits	373	Target Neighborhood Hits	346	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

APXL_HUMAN
NC score	0.340443 (rank : 125)	θ value	0.00390308 (rank : 167)
Query Neighborhood Hits	373	Target Neighborhood Hits	553	Shared Neighborhood Hits	129
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

DVL1_HUMAN
NC score	0.339972 (rank : 126)	θ value	0.0330416 (rank : 195)
Query Neighborhood Hits	373	Target Neighborhood Hits	158	Shared Neighborhood Hits	120
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

PDLI3_HUMAN
NC score	0.337634 (rank : 127)	θ value	0.000786445 (rank : 154)
Query Neighborhood Hits	373	Target Neighborhood Hits	199	Shared Neighborhood Hits	110
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

DVL1_MOUSE
NC score	0.337240 (rank : 128)	θ value	0.0252991 (rank : 193)
Query Neighborhood Hits	373	Target Neighborhood Hits	146	Shared Neighborhood Hits	119
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

RPGF6_HUMAN
NC score	0.336970 (rank : 129)	θ value	0.00869519 (rank : 178)
Query Neighborhood Hits	373	Target Neighborhood Hits	266	Shared Neighborhood Hits	155
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PAR6G_HUMAN
NC score	0.334337 (rank : 130)	θ value	0.0431538 (rank : 201)
Query Neighborhood Hits	373	Target Neighborhood Hits	159	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PDLI1_MOUSE
NC score	0.332023 (rank : 131)	θ value	0.00102713 (rank : 157)
Query Neighborhood Hits	373	Target Neighborhood Hits	213	Shared Neighborhood Hits	107
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

ARHGB_HUMAN
NC score	0.330204 (rank : 132)	θ value	1.69304e-06 (rank : 94)
Query Neighborhood Hits	373	Target Neighborhood Hits	375	Shared Neighborhood Hits	162
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PAR6B_HUMAN
NC score	0.329214 (rank : 133)	θ value	0.62314 (rank : 237)
Query Neighborhood Hits	373	Target Neighborhood Hits	126	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
NC score	0.328039 (rank : 134)	θ value	0.62314 (rank : 238)
Query Neighborhood Hits	373	Target Neighborhood Hits	128	Shared Neighborhood Hits	121
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

DVL1L_HUMAN
NC score	0.327546 (rank : 135)	θ value	0.0193708 (rank : 186)
Query Neighborhood Hits	373	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

PDLI4_HUMAN
NC score	0.326481 (rank : 136)	θ value	0.00665767 (rank : 173)
Query Neighborhood Hits	373	Target Neighborhood Hits	245	Shared Neighborhood Hits	114
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
NC score	0.325068 (rank : 137)	θ value	0.00869519 (rank : 177)
Query Neighborhood Hits	373	Target Neighborhood Hits	233	Shared Neighborhood Hits	116
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI1_HUMAN
NC score	0.324692 (rank : 138)	θ value	0.00665767 (rank : 172)
Query Neighborhood Hits	373	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

MPP6_MOUSE
NC score	0.323709 (rank : 139)	θ value	0.000786445 (rank : 153)
Query Neighborhood Hits	373	Target Neighborhood Hits	187	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

PAR6A_MOUSE
NC score	0.321877 (rank : 140)	θ value	0.0736092 (rank : 208)
Query Neighborhood Hits	373	Target Neighborhood Hits	115	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

SDCB1_MOUSE
NC score	0.321625 (rank : 141)	θ value	0.47712 (rank : 231)
Query Neighborhood Hits	373	Target Neighborhood Hits	144	Shared Neighborhood Hits	134
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

DVL2_HUMAN
NC score	0.321403 (rank : 142)	θ value	0.0736092 (rank : 206)
Query Neighborhood Hits	373	Target Neighborhood Hits	223	Shared Neighborhood Hits	121
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.320099 (rank : 143)	θ value	0.0736092 (rank : 207)
Query Neighborhood Hits	373	Target Neighborhood Hits	233	Shared Neighborhood Hits	122
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

MPP2_MOUSE
NC score	0.319085 (rank : 144)	θ value	0.0113563 (rank : 180)
Query Neighborhood Hits	373	Target Neighborhood Hits	189	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

YAP1_HUMAN
NC score	0.319076 (rank : 145)	θ value	1.87187e-05 (rank : 115)
Query Neighborhood Hits	373	Target Neighborhood Hits	173	Shared Neighborhood Hits	58
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

MPP6_HUMAN
NC score	0.318364 (rank : 146)	θ value	0.00175202 (rank : 163)
Query Neighborhood Hits	373	Target Neighborhood Hits	180	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

PAR6A_HUMAN
NC score	0.318214 (rank : 147)	θ value	0.21417 (rank : 220)
Query Neighborhood Hits	373	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

MPP2_HUMAN
NC score	0.315936 (rank : 148)	θ value	0.00869519 (rank : 175)
Query Neighborhood Hits	373	Target Neighborhood Hits	173	Shared Neighborhood Hits	97
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

RHPN1_HUMAN
NC score	0.315461 (rank : 149)	θ value	0.0330416 (rank : 198)
Query Neighborhood Hits	373	Target Neighborhood Hits	158	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

WWP2_HUMAN
NC score	0.315267 (rank : 150)	θ value	1.9326e-10 (rank : 45)
Query Neighborhood Hits	373	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
NC score	0.315036 (rank : 151)	θ value	1.47974e-10 (rank : 42)
Query Neighborhood Hits	373	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

PDLI3_MOUSE
NC score	0.313344 (rank : 152)	θ value	0.0113563 (rank : 181)
Query Neighborhood Hits	373	Target Neighborhood Hits	197	Shared Neighborhood Hits	106
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

WWP1_MOUSE
NC score	0.309937 (rank : 153)	θ value	4.30538e-10 (rank : 49)
Query Neighborhood Hits	373	Target Neighborhood Hits	138	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

SDCB1_HUMAN
NC score	0.309847 (rank : 154)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	373	Target Neighborhood Hits	150	Shared Neighborhood Hits	140
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

ITCH_MOUSE
NC score	0.307750 (rank : 155)	θ value	5.08577e-11 (rank : 33)
Query Neighborhood Hits	373	Target Neighborhood Hits	127	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

SHAN2_MOUSE
NC score	0.306888 (rank : 156)	θ value	0.000270298 (rank : 144)
Query Neighborhood Hits	373	Target Neighborhood Hits	446	Shared Neighborhood Hits	136
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

WWP1_HUMAN
NC score	0.306662 (rank : 157)	θ value	1.25267e-09 (rank : 56)
Query Neighborhood Hits	373	Target Neighborhood Hits	262	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWTR1_MOUSE
NC score	0.306625 (rank : 158)	θ value	0.000158464 (rank : 135)
Query Neighborhood Hits	373	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

ITCH_HUMAN
NC score	0.305990 (rank : 159)	θ value	8.67504e-11 (rank : 35)
Query Neighborhood Hits	373	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

WWTR1_HUMAN
NC score	0.304663 (rank : 160)	θ value	9.29e-05 (rank : 130)
Query Neighborhood Hits	373	Target Neighborhood Hits	76	Shared Neighborhood Hits	42
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

ARHGC_HUMAN
NC score	0.303325 (rank : 161)	θ value	4.1701e-05 (rank : 125)
Query Neighborhood Hits	373	Target Neighborhood Hits	351	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.299647 (rank : 162)	θ value	9.29e-05 (rank : 129)
Query Neighborhood Hits	373	Target Neighborhood Hits	344	Shared Neighborhood Hits	150
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

WWOX_HUMAN
NC score	0.292767 (rank : 163)	θ value	3.89403e-11 (rank : 31)
Query Neighborhood Hits	373	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

SMUF2_HUMAN
NC score	0.292418 (rank : 164)	θ value	9.59137e-10 (rank : 53)
Query Neighborhood Hits	373	Target Neighborhood Hits	142	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_MOUSE
NC score	0.291841 (rank : 165)	θ value	7.34386e-10 (rank : 50)
Query Neighborhood Hits	373	Target Neighborhood Hits	142	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

WWOX_MOUSE
NC score	0.290156 (rank : 166)	θ value	3.89403e-11 (rank : 32)
Query Neighborhood Hits	373	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

NEDD4_HUMAN
NC score	0.286712 (rank : 167)	θ value	1.47974e-10 (rank : 41)
Query Neighborhood Hits	373	Target Neighborhood Hits	214	Shared Neighborhood Hits	45
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

RPGF2_HUMAN
NC score	0.284257 (rank : 168)	θ value	0.365318 (rank : 228)
Query Neighborhood Hits	373	Target Neighborhood Hits	242	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SDCB2_MOUSE
NC score	0.282596 (rank : 169)	θ value	0.813845 (rank : 244)
Query Neighborhood Hits	373	Target Neighborhood Hits	118	Shared Neighborhood Hits	111
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

RGS12_HUMAN
NC score	0.281813 (rank : 170)	θ value	0.0431538 (rank : 203)
Query Neighborhood Hits	373	Target Neighborhood Hits	333	Shared Neighborhood Hits	145
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

LDB3_MOUSE
NC score	0.280644 (rank : 171)	θ value	5.26297e-08 (rank : 74)
Query Neighborhood Hits	373	Target Neighborhood Hits	510	Shared Neighborhood Hits	127
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

SMUF1_HUMAN
NC score	0.280353 (rank : 172)	θ value	1.99992e-07 (rank : 83)
Query Neighborhood Hits	373	Target Neighborhood Hits	135	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

NED4L_MOUSE
NC score	0.280293 (rank : 173)	θ value	1.38499e-08 (rank : 68)
Query Neighborhood Hits	373	Target Neighborhood Hits	231	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
NC score	0.279957 (rank : 174)	θ value	1.38499e-08 (rank : 67)
Query Neighborhood Hits	373	Target Neighborhood Hits	238	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_MOUSE
NC score	0.279462 (rank : 175)	θ value	1.06045e-08 (rank : 63)
Query Neighborhood Hits	373	Target Neighborhood Hits	212	Shared Neighborhood Hits	44
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

LDB3_HUMAN
NC score	0.277421 (rank : 176)	θ value	1.09739e-05 (rank : 111)
Query Neighborhood Hits	373	Target Neighborhood Hits	497	Shared Neighborhood Hits	133
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

GIPC1_MOUSE
NC score	0.277394 (rank : 177)	θ value	0.00298849 (rank : 165)
Query Neighborhood Hits	373	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

PDLI5_MOUSE
NC score	0.272864 (rank : 178)	θ value	3.77169e-06 (rank : 101)
Query Neighborhood Hits	373	Target Neighborhood Hits	287	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_HUMAN
NC score	0.271522 (rank : 179)	θ value	6.43352e-06 (rank : 106)
Query Neighborhood Hits	373	Target Neighborhood Hits	322	Shared Neighborhood Hits	121
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SDCB2_HUMAN
NC score	0.270153 (rank : 180)	θ value	1.38821 (rank : 257)
Query Neighborhood Hits	373	Target Neighborhood Hits	121	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

NOS1_HUMAN
NC score	0.269827 (rank : 181)	θ value	0.0193708 (rank : 192)
Query Neighborhood Hits	373	Target Neighborhood Hits	218	Shared Neighborhood Hits	140
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

GIPC1_HUMAN
NC score	0.265766 (rank : 182)	θ value	0.00390308 (rank : 168)
Query Neighborhood Hits	373	Target Neighborhood Hits	91	Shared Neighborhood Hits	88
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

BAG3_HUMAN
NC score	0.265489 (rank : 183)	θ value	0.000270298 (rank : 140)
Query Neighborhood Hits	373	Target Neighborhood Hits	314	Shared Neighborhood Hits	61
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

KGUA_HUMAN
NC score	0.262332 (rank : 184)	θ value	0.163984 (rank : 217)
Query Neighborhood Hits	373	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
NC score	0.259348 (rank : 185)	θ value	0.125558 (rank : 214)
Query Neighborhood Hits	373	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

PDLI7_HUMAN
NC score	0.257285 (rank : 186)	θ value	8.40245e-06 (rank : 108)
Query Neighborhood Hits	373	Target Neighborhood Hits	547	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

CNKR2_MOUSE
NC score	0.254034 (rank : 187)	θ value	1.38499e-08 (rank : 66)
Query Neighborhood Hits	373	Target Neighborhood Hits	197	Shared Neighborhood Hits	59
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.253986 (rank : 188)	θ value	1.38499e-08 (rank : 65)
Query Neighborhood Hits	373	Target Neighborhood Hits	197	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PDLI7_MOUSE
NC score	0.249393 (rank : 189)	θ value	0.000158464 (rank : 134)
Query Neighborhood Hits	373	Target Neighborhood Hits	279	Shared Neighborhood Hits	109
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PKHA5_HUMAN
NC score	0.241571 (rank : 190)	θ value	9.92553e-07 (rank : 90)
Query Neighborhood Hits	373	Target Neighborhood Hits	455	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

BAG3_MOUSE
NC score	0.240348 (rank : 191)	θ value	0.00020696 (rank : 136)
Query Neighborhood Hits	373	Target Neighborhood Hits	513	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

NOS1_MOUSE
NC score	0.235761 (rank : 192)	θ value	0.365318 (rank : 225)
Query Neighborhood Hits	373	Target Neighborhood Hits	155	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

GIPC2_HUMAN
NC score	0.226472 (rank : 193)	θ value	0.0193708 (rank : 189)
Query Neighborhood Hits	373	Target Neighborhood Hits	93	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

SHAN1_HUMAN
NC score	0.217296 (rank : 194)	θ value	3.19293e-05 (rank : 124)
Query Neighborhood Hits	373	Target Neighborhood Hits	1041	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

LRRC7_HUMAN
NC score	0.216584 (rank : 195)	θ value	0.000270298 (rank : 141)
Query Neighborhood Hits	373	Target Neighborhood Hits	423	Shared Neighborhood Hits	119
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.215572 (rank : 196)	θ value	0.000270298 (rank : 142)
Query Neighborhood Hits	373	Target Neighborhood Hits	416	Shared Neighborhood Hits	119
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

RIMS1_HUMAN
NC score	0.213499 (rank : 197)	θ value	0.813845 (rank : 243)
Query Neighborhood Hits	373	Target Neighborhood Hits	437	Shared Neighborhood Hits	145
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PCLO_MOUSE
NC score	0.203117 (rank : 198)	θ value	0.000270298 (rank : 143)
Query Neighborhood Hits	373	Target Neighborhood Hits	2275	Shared Neighborhood Hits	229
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

LAP2_HUMAN
NC score	0.196528 (rank : 199)	θ value	0.00869519 (rank : 174)
Query Neighborhood Hits	373	Target Neighborhood Hits	499	Shared Neighborhood Hits	116
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PINL_HUMAN
NC score	0.187972 (rank : 200)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	373	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

RIMS2_HUMAN
NC score	0.186469 (rank : 201)	θ value	0.365318 (rank : 226)
Query Neighborhood Hits	373	Target Neighborhood Hits	342	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.185734 (rank : 202)	θ value	0.365318 (rank : 227)
Query Neighborhood Hits	373	Target Neighborhood Hits	376	Shared Neighborhood Hits	118
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

LAP2_MOUSE
NC score	0.184363 (rank : 203)	θ value	0.0330416 (rank : 196)
Query Neighborhood Hits	373	Target Neighborhood Hits	482	Shared Neighborhood Hits	114
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

GIPC3_HUMAN
NC score	0.177865 (rank : 204)	θ value	0.0563607 (rank : 204)
Query Neighborhood Hits	373	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC2_MOUSE
NC score	0.174074 (rank : 205)	θ value	0.0431538 (rank : 199)
Query Neighborhood Hits	373	Target Neighborhood Hits	71	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GIPC3_MOUSE
NC score	0.171224 (rank : 206)	θ value	0.0563607 (rank : 205)
Query Neighborhood Hits	373	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

PTN4_HUMAN
NC score	0.169998 (rank : 207)	θ value	2.88788e-06 (rank : 99)
Query Neighborhood Hits	373	Target Neighborhood Hits	303	Shared Neighborhood Hits	126
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.169241 (rank : 208)	θ value	3.19293e-05 (rank : 123)
Query Neighborhood Hits	373	Target Neighborhood Hits	258	Shared Neighborhood Hits	116
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PIN1_MOUSE
NC score	0.164872 (rank : 209)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	373	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_HUMAN
NC score	0.163705 (rank : 210)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	373	Target Neighborhood Hits	59	Shared Neighborhood Hits	35
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PDZD6_HUMAN
NC score	0.161989 (rank : 211)	θ value	0.62314 (rank : 239)
Query Neighborhood Hits	373	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

HUWE1_MOUSE
NC score	0.153519 (rank : 212)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	373	Target Neighborhood Hits	406	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.152270 (rank : 213)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	373	Target Neighborhood Hits	443	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

K0317_HUMAN
NC score	0.150260 (rank : 214)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	373	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.150207 (rank : 215)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	373	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

HECD2_MOUSE
NC score	0.143437 (rank : 216)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	373	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_HUMAN
NC score	0.142615 (rank : 217)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	373	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

TRIPC_HUMAN
NC score	0.139603 (rank : 218)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	373	Target Neighborhood Hits	319	Shared Neighborhood Hits	32
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

UBE3A_HUMAN
NC score	0.138845 (rank : 219)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	373	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3C_HUMAN
NC score	0.137198 (rank : 220)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	373	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3A_MOUSE
NC score	0.136992 (rank : 221)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	373	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_MOUSE
NC score	0.136901 (rank : 222)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	373	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

CSKP_HUMAN
NC score	0.131622 (rank : 223)	θ value	2.44474e-05 (rank : 117)
Query Neighborhood Hits	373	Target Neighborhood Hits	1022	Shared Neighborhood Hits	132
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
NC score	0.128846 (rank : 224)	θ value	2.44474e-05 (rank : 118)
Query Neighborhood Hits	373	Target Neighborhood Hits	1027	Shared Neighborhood Hits	132
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CNKR1_HUMAN
NC score	0.122428 (rank : 225)	θ value	0.0148317 (rank : 182)
Query Neighborhood Hits	373	Target Neighborhood Hits	154	Shared Neighborhood Hits	26
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

HERC5_HUMAN
NC score	0.118389 (rank : 226)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	373	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC3_HUMAN
NC score	0.114998 (rank : 227)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	373	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

RGS3_HUMAN
NC score	0.109943 (rank : 228)	θ value	0.000786445 (rank : 156)
Query Neighborhood Hits	373	Target Neighborhood Hits	1375	Shared Neighborhood Hits	136
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

VCY1_HUMAN
NC score	0.101045 (rank : 229)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	373	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

HECD3_MOUSE
NC score	0.100018 (rank : 230)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	373	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

EDD1_HUMAN
NC score	0.099229 (rank : 231)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	373	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
NC score	0.099045 (rank : 232)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	373	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

RGS3_MOUSE
NC score	0.098592 (rank : 233)	θ value	0.0330416 (rank : 197)
Query Neighborhood Hits	373	Target Neighborhood Hits	1621	Shared Neighborhood Hits	151
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

HECD3_HUMAN
NC score	0.098255 (rank : 234)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	373	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC2_MOUSE
NC score	0.093502 (rank : 235)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	373	Target Neighborhood Hits	167	Shared Neighborhood Hits	23
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

GAS7_HUMAN
NC score	0.092929 (rank : 236)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	373	Target Neighborhood Hits	258	Shared Neighborhood Hits	43
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

HERC2_HUMAN
NC score	0.092341 (rank : 237)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	373	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

PRAX_MOUSE
NC score	0.090149 (rank : 238)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	373	Target Neighborhood Hits	199	Shared Neighborhood Hits	54
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PDZD8_HUMAN
NC score	0.089410 (rank : 239)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	373	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

GAS7_MOUSE
NC score	0.088082 (rank : 240)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	373	Target Neighborhood Hits	259	Shared Neighborhood Hits	41
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

HECD1_HUMAN
NC score	0.086013 (rank : 241)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	373	Target Neighborhood Hits	371	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

MAST4_HUMAN
NC score	0.085679 (rank : 242)	θ value	4.1701e-05 (rank : 126)
Query Neighborhood Hits	373	Target Neighborhood Hits	1804	Shared Neighborhood Hits	191
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MY18A_MOUSE
NC score	0.082765 (rank : 243)	θ value	0.00869519 (rank : 176)
Query Neighborhood Hits	373	Target Neighborhood Hits	1989	Shared Neighborhood Hits	165
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MAST3_HUMAN
NC score	0.082287 (rank : 244)	θ value	4.92598e-06 (rank : 103)
Query Neighborhood Hits	373	Target Neighborhood Hits	1128	Shared Neighborhood Hits	148
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

WWC3_HUMAN
NC score	0.080919 (rank : 245)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	373	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

MAST1_MOUSE
NC score	0.080853 (rank : 246)	θ value	0.000461057 (rank : 148)
Query Neighborhood Hits	373	Target Neighborhood Hits	1123	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_HUMAN
NC score	0.080095 (rank : 247)	θ value	0.000602161 (rank : 151)
Query Neighborhood Hits	373	Target Neighborhood Hits	1189	Shared Neighborhood Hits	141
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST1_HUMAN
NC score	0.079990 (rank : 248)	θ value	0.000461057 (rank : 147)
Query Neighborhood Hits	373	Target Neighborhood Hits	1146	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

LMO7_HUMAN
NC score	0.078623 (rank : 249)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	373	Target Neighborhood Hits	507	Shared Neighborhood Hits	67
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MAST2_MOUSE
NC score	0.078365 (rank : 250)	θ value	0.000602161 (rank : 152)
Query Neighborhood Hits	373	Target Neighborhood Hits	1110	Shared Neighborhood Hits	137
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

RHPN2_MOUSE
NC score	0.076464 (rank : 251)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	373	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

SRRM2_HUMAN
NC score	0.075652 (rank : 252)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	373	Target Neighborhood Hits	1296	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TIAM1_HUMAN
NC score	0.074688 (rank : 253)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	373	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

MY18A_HUMAN
NC score	0.073751 (rank : 254)	θ value	0.0431538 (rank : 200)
Query Neighborhood Hits	373	Target Neighborhood Hits	1929	Shared Neighborhood Hits	165
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SRRM2_MOUSE
NC score	0.067809 (rank : 255)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	373	Target Neighborhood Hits	1470	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PRP40_HUMAN
NC score	0.064994 (rank : 256)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	373	Target Neighborhood Hits	442	Shared Neighborhood Hits	48
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRAX_HUMAN
NC score	0.064507 (rank : 257)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	373	Target Neighborhood Hits	215	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRP40_MOUSE
NC score	0.064347 (rank : 258)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	373	Target Neighborhood Hits	447	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

SRRM1_MOUSE
NC score	0.063148 (rank : 259)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	373	Target Neighborhood Hits	966	Shared Neighborhood Hits	100
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

HTRA3_MOUSE
NC score	0.062148 (rank : 260)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	373	Target Neighborhood Hits	156	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

SETD2_HUMAN
NC score	0.061422 (rank : 261)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	373	Target Neighborhood Hits	412	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

PCLO_HUMAN
NC score	0.061089 (rank : 262)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	373	Target Neighborhood Hits	2046	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RNF41_HUMAN
NC score	0.060489 (rank : 263)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	373	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.060456 (rank : 264)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	373	Target Neighborhood Hits	224	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TARA_HUMAN
NC score	0.060209 (rank : 265)	θ value	0.62314 (rank : 240)
Query Neighborhood Hits	373	Target Neighborhood Hits	1626	Shared Neighborhood Hits	107
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CAR11_HUMAN
NC score	0.058563 (rank : 266)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	373	Target Neighborhood Hits	690	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

MDC1_HUMAN
NC score	0.058388 (rank : 267)	θ value	0.813845 (rank : 241)
Query Neighborhood Hits	373	Target Neighborhood Hits	1446	Shared Neighborhood Hits	105
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

BAT2_HUMAN
NC score	0.057926 (rank : 268)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	373	Target Neighborhood Hits	931	Shared Neighborhood Hits	100
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NFH_MOUSE
NC score	0.057630 (rank : 269)	θ value	1.06045e-08 (rank : 64)
Query Neighborhood Hits	373	Target Neighborhood Hits	2247	Shared Neighborhood Hits	143
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

APBB2_HUMAN
NC score	0.057139 (rank : 270)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	373	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

RAIN_HUMAN
NC score	0.056566 (rank : 271)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	373	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

HTRA3_HUMAN
NC score	0.056542 (rank : 272)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	373	Target Neighborhood Hits	152	Shared Neighborhood Hits	59
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

RAIN_MOUSE
NC score	0.055738 (rank : 273)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	373	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q3U0S6, Q6GQW4	Gene names	Rasip1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

CBP_MOUSE
NC score	0.055032 (rank : 274)	θ value	0.163984 (rank : 216)
Query Neighborhood Hits	373	Target Neighborhood Hits	1051	Shared Neighborhood Hits	88
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SRRM1_HUMAN
NC score	0.054923 (rank : 275)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	373	Target Neighborhood Hits	690	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

AFF1_HUMAN
NC score	0.054669 (rank : 276)	θ value	0.279714 (rank : 221)
Query Neighborhood Hits	373	Target Neighborhood Hits	506	Shared Neighborhood Hits	56
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

NCOR2_HUMAN
NC score	0.054387 (rank : 277)	θ value	1.81305 (rank : 264)
Query Neighborhood Hits	373	Target Neighborhood Hits	870	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NACAM_MOUSE
NC score	0.053676 (rank : 278)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	373	Target Neighborhood Hits	1866	Shared Neighborhood Hits	129
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OGFR_HUMAN
NC score	0.053069 (rank : 279)	θ value	0.47712 (rank : 230)
Query Neighborhood Hits	373	Target Neighborhood Hits	1582	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

LPXN_HUMAN
NC score	0.052874 (rank : 280)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	373	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	O60711	Gene names	LPXN, LDLP
Domain Architecture
Description	Leupaxin.

CBP_HUMAN
NC score	0.052834 (rank : 281)	θ value	0.365318 (rank : 224)
Query Neighborhood Hits	373	Target Neighborhood Hits	941	Shared Neighborhood Hits	81
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CF150_HUMAN
NC score	0.052184 (rank : 282)	θ value	0.125558 (rank : 212)
Query Neighborhood Hits	373	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

PTN23_MOUSE
NC score	0.052087 (rank : 283)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	373	Target Neighborhood Hits	726	Shared Neighborhood Hits	69
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CAR14_HUMAN
NC score	0.051944 (rank : 284)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	373	Target Neighborhood Hits	449	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

NCOR2_MOUSE
NC score	0.051638 (rank : 285)	θ value	0.0961366 (rank : 209)
Query Neighborhood Hits	373	Target Neighborhood Hits	790	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

LPXN_MOUSE
NC score	0.050772 (rank : 286)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	373	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

PINC_HUMAN
NC score	0.050223 (rank : 287)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	373	Target Neighborhood Hits	231	Shared Neighborhood Hits	20
SwissProt Accessions	P48059, Q53TE0, Q9BS44	Gene names	LIMS1
Domain Architecture
Description	Protein PINCH (Particularly interesting new Cys-His protein) (LIM and senescent cell antigen-like domains 1) (NY-REN-48 antigen).

PAXI_MOUSE
NC score	0.050178 (rank : 288)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	373	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

TIAM1_MOUSE
NC score	0.050150 (rank : 289)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	373	Target Neighborhood Hits	205	Shared Neighborhood Hits	51
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PAXI_HUMAN
NC score	0.050122 (rank : 290)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	373	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

MARCS_HUMAN
NC score	0.050043 (rank : 291)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	373	Target Neighborhood Hits	204	Shared Neighborhood Hits	31
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

RHG12_MOUSE
NC score	0.049213 (rank : 292)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	373	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

ABLM3_MOUSE
NC score	0.048150 (rank : 293)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	373	Target Neighborhood Hits	294	Shared Neighborhood Hits	26
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM3_HUMAN
NC score	0.046938 (rank : 294)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	373	Target Neighborhood Hits	293	Shared Neighborhood Hits	25
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

SF3B1_MOUSE
NC score	0.046020 (rank : 295)	θ value	0.279714 (rank : 223)
Query Neighborhood Hits	373	Target Neighborhood Hits	352	Shared Neighborhood Hits	36
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_HUMAN
NC score	0.045971 (rank : 296)	θ value	0.279714 (rank : 222)
Query Neighborhood Hits	373	Target Neighborhood Hits	341	Shared Neighborhood Hits	35
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CGRE1_HUMAN
NC score	0.045564 (rank : 297)	θ value	0.0193708 (rank : 185)
Query Neighborhood Hits	373	Target Neighborhood Hits	354	Shared Neighborhood Hits	25
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CASC3_MOUSE
NC score	0.045377 (rank : 298)	θ value	0.62314 (rank : 232)
Query Neighborhood Hits	373	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

LIMK1_MOUSE
NC score	0.044458 (rank : 299)	θ value	0.00298849 (rank : 166)
Query Neighborhood Hits	373	Target Neighborhood Hits	1008	Shared Neighborhood Hits	92
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

LIMK1_HUMAN
NC score	0.043824 (rank : 300)	θ value	0.0193708 (rank : 190)
Query Neighborhood Hits	373	Target Neighborhood Hits	1005	Shared Neighborhood Hits	89
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

BAT2_MOUSE
NC score	0.043387 (rank : 301)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	373	Target Neighborhood Hits	947	Shared Neighborhood Hits	94
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RHG12_HUMAN
NC score	0.043068 (rank : 302)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	373	Target Neighborhood Hits	190	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CIC_HUMAN
NC score	0.042299 (rank : 303)	θ value	2.36792 (rank : 272)
Query Neighborhood Hits	373	Target Neighborhood Hits	992	Shared Neighborhood Hits	78
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TXND2_HUMAN
NC score	0.040714 (rank : 304)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	373	Target Neighborhood Hits	793	Shared Neighborhood Hits	65
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

YLPM1_HUMAN
NC score	0.039798 (rank : 305)	θ value	8.99809 (rank : 373)
Query Neighborhood Hits	373	Target Neighborhood Hits	670	Shared Neighborhood Hits	67
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

OGFR_MOUSE
NC score	0.038792 (rank : 306)	θ value	0.813845 (rank : 242)
Query Neighborhood Hits	373	Target Neighborhood Hits	584	Shared Neighborhood Hits	55
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

TARSH_HUMAN
NC score	0.037150 (rank : 307)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	373	Target Neighborhood Hits	768	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MBD6_HUMAN
NC score	0.036825 (rank : 308)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	373	Target Neighborhood Hits	349	Shared Neighborhood Hits	38
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

IRS2_HUMAN
NC score	0.034914 (rank : 309)	θ value	1.81305 (rank : 261)
Query Neighborhood Hits	373	Target Neighborhood Hits	262	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

NCOA6_HUMAN
NC score	0.034791 (rank : 310)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	373	Target Neighborhood Hits	1202	Shared Neighborhood Hits	94
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MLL2_HUMAN
NC score	0.034687 (rank : 311)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	373	Target Neighborhood Hits	1788	Shared Neighborhood Hits	113
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

IF4G1_MOUSE
NC score	0.033859 (rank : 312)	θ value	0.125558 (rank : 213)
Query Neighborhood Hits	373	Target Neighborhood Hits	534	Shared Neighborhood Hits	51
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

RP1L1_HUMAN
NC score	0.033407 (rank : 313)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	373	Target Neighborhood Hits	1072	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

GRIN1_HUMAN
NC score	0.032374 (rank : 314)	θ value	3.0926 (rank : 283)
Query Neighborhood Hits	373	Target Neighborhood Hits	681	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ACD_HUMAN
NC score	0.031742 (rank : 315)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	373	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

LHX3_MOUSE
NC score	0.030578 (rank : 316)	θ value	1.81305 (rank : 263)
Query Neighborhood Hits	373	Target Neighborhood Hits	451	Shared Neighborhood Hits	24
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

IF4G1_HUMAN
NC score	0.030373 (rank : 317)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	373	Target Neighborhood Hits	347	Shared Neighborhood Hits	38
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

SON_HUMAN
NC score	0.029683 (rank : 318)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	373	Target Neighborhood Hits	1568	Shared Neighborhood Hits	97
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

LR37A_HUMAN
NC score	0.029676 (rank : 319)	θ value	0.62314 (rank : 235)
Query Neighborhood Hits	373	Target Neighborhood Hits	720	Shared Neighborhood Hits	52
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NCOA6_MOUSE
NC score	0.029482 (rank : 320)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	373	Target Neighborhood Hits	1076	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SYNJ1_HUMAN
NC score	0.028922 (rank : 321)	θ value	3.0926 (rank : 291)
Query Neighborhood Hits	373	Target Neighborhood Hits	498	Shared Neighborhood Hits	56
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CRSP2_HUMAN
NC score	0.028632 (rank : 322)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	373	Target Neighborhood Hits	380	Shared Neighborhood Hits	41
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

MAP1B_HUMAN
NC score	0.028387 (rank : 323)	θ value	2.36792 (rank : 276)
Query Neighborhood Hits	373	Target Neighborhood Hits	903	Shared Neighborhood Hits	58
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

GTSE1_MOUSE
NC score	0.027724 (rank : 324)	θ value	2.36792 (rank : 274)
Query Neighborhood Hits	373	Target Neighborhood Hits	245	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

TP53B_MOUSE
NC score	0.027392 (rank : 325)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	373	Target Neighborhood Hits	644	Shared Neighborhood Hits	50
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SMOO_HUMAN
NC score	0.026952 (rank : 326)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	373	Target Neighborhood Hits	391	Shared Neighborhood Hits	51
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

MAGD1_MOUSE
NC score	0.026109 (rank : 327)	θ value	0.62314 (rank : 236)
Query Neighborhood Hits	373	Target Neighborhood Hits	136	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QYH6, Q543L6, Q99PB5, Q9CYX1	Gene names	Maged1, Nrage
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (Dlxin-1).

DMD_HUMAN
NC score	0.025455 (rank : 328)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	373	Target Neighborhood Hits	1135	Shared Neighborhood Hits	56
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

CO039_HUMAN
NC score	0.025080 (rank : 329)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	373	Target Neighborhood Hits	264	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CCDC9_HUMAN
NC score	0.024847 (rank : 330)	θ value	1.81305 (rank : 260)
Query Neighborhood Hits	373	Target Neighborhood Hits	175	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

DIDO1_HUMAN
NC score	0.024600 (rank : 331)	θ value	2.36792 (rank : 273)
Query Neighborhood Hits	373	Target Neighborhood Hits	960	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CS021_HUMAN
NC score	0.023918 (rank : 332)	θ value	0.62314 (rank : 233)
Query Neighborhood Hits	373	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

DMD_MOUSE
NC score	0.023712 (rank : 333)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	373	Target Neighborhood Hits	1111	Shared Neighborhood Hits	58
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

LEUK_MOUSE
NC score	0.022807 (rank : 334)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	373	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

G3PT_MOUSE
NC score	0.022668 (rank : 335)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	373	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

ZN385_HUMAN
NC score	0.022491 (rank : 336)	θ value	1.06291 (rank : 249)
Query Neighborhood Hits	373	Target Neighborhood Hits	614	Shared Neighborhood Hits	45
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

K1688_HUMAN
NC score	0.022180 (rank : 337)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	373	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

BAZ2A_HUMAN
NC score	0.021254 (rank : 338)	θ value	1.81305 (rank : 259)
Query Neighborhood Hits	373	Target Neighborhood Hits	780	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

MA1B1_HUMAN
NC score	0.020975 (rank : 339)	θ value	1.38821 (rank : 253)
Query Neighborhood Hits	373	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MAGD1_HUMAN
NC score	0.020840 (rank : 340)	θ value	0.21417 (rank : 219)
Query Neighborhood Hits	373	Target Neighborhood Hits	130	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

MY18B_HUMAN
NC score	0.020834 (rank : 341)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	373	Target Neighborhood Hits	1299	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

PO6F2_MOUSE
NC score	0.020812 (rank : 342)	θ value	1.06291 (rank : 247)
Query Neighborhood Hits	373	Target Neighborhood Hits	639	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

UTRO_HUMAN
NC score	0.020687 (rank : 343)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	373	Target Neighborhood Hits	960	Shared Neighborhood Hits	54
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

RBM6_HUMAN
NC score	0.020418 (rank : 344)	θ value	1.38821 (rank : 255)
Query Neighborhood Hits	373	Target Neighborhood Hits	221	Shared Neighborhood Hits	10
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

SPF45_HUMAN
NC score	0.019933 (rank : 345)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	373	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

CAC1A_MOUSE
NC score	0.019841 (rank : 346)	θ value	0.47712 (rank : 229)
Query Neighborhood Hits	373	Target Neighborhood Hits	267	Shared Neighborhood Hits	36
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

HGS_MOUSE
NC score	0.019697 (rank : 347)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	373	Target Neighborhood Hits	589	Shared Neighborhood Hits	54
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

GASP2_MOUSE
NC score	0.019642 (rank : 348)	θ value	1.06291 (rank : 245)
Query Neighborhood Hits	373	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

LEF1_HUMAN
NC score	0.019581 (rank : 349)	θ value	0.21417 (rank : 218)
Query Neighborhood Hits	373	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

GP137_MOUSE
NC score	0.019413 (rank : 350)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	373	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q60865, Q60758, Q61620	Gene names	M11s1, Gpiap, Gpiap1, Gpip137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI).

NUFP1_HUMAN
NC score	0.019063 (rank : 351)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	373	Target Neighborhood Hits	193	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

NOP14_HUMAN
NC score	0.018773 (rank : 352)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	373	Target Neighborhood Hits	573	Shared Neighborhood Hits	26
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

GT2D1_HUMAN
NC score	0.018485 (rank : 353)	θ value	0.62314 (rank : 234)
Query Neighborhood Hits	373	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

UBP42_HUMAN
NC score	0.017629 (rank : 354)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	373	Target Neighborhood Hits	445	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

JPH2_HUMAN
NC score	0.017606 (rank : 355)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	373	Target Neighborhood Hits	639	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TE2IP_MOUSE
NC score	0.017173 (rank : 356)	θ value	2.36792 (rank : 278)
Query Neighborhood Hits	373	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VL8, Q543F4, Q9JJE8, Q9JJE9	Gene names	Terf2ip, Rap1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1).

CTRO_HUMAN
NC score	0.016251 (rank : 357)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	373	Target Neighborhood Hits	2092	Shared Neighborhood Hits	66
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

LSD1_HUMAN
NC score	0.015701 (rank : 358)	θ value	2.36792 (rank : 275)
Query Neighborhood Hits	373	Target Neighborhood Hits	455	Shared Neighborhood Hits	27
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LEF1_MOUSE
NC score	0.015283 (rank : 359)	θ value	1.06291 (rank : 246)
Query Neighborhood Hits	373	Target Neighborhood Hits	161	Shared Neighborhood Hits	7
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

CCNK_HUMAN
NC score	0.015205 (rank : 360)	θ value	3.0926 (rank : 282)
Query Neighborhood Hits	373	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

CTRO_MOUSE
NC score	0.015034 (rank : 361)	θ value	1.38821 (rank : 251)
Query Neighborhood Hits	373	Target Neighborhood Hits	2344	Shared Neighborhood Hits	74
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

NOXO1_HUMAN
NC score	0.014699 (rank : 362)	θ value	2.36792 (rank : 277)
Query Neighborhood Hits	373	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NCTR2_HUMAN
NC score	0.014518 (rank : 363)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	373	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

CENPC_MOUSE
NC score	0.014478 (rank : 364)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	373	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

CLSPN_MOUSE
NC score	0.014344 (rank : 365)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	373	Target Neighborhood Hits	292	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

THAP7_MOUSE
NC score	0.013628 (rank : 366)	θ value	8.99809 (rank : 371)
Query Neighborhood Hits	373	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

SMRA3_MOUSE
NC score	0.013353 (rank : 367)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	373	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

CLIC6_HUMAN
NC score	0.013317 (rank : 368)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	373	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

USP9X_HUMAN
NC score	0.013111 (rank : 369)	θ value	1.81305 (rank : 267)
Query Neighborhood Hits	373	Target Neighborhood Hits	161	Shared Neighborhood Hits	12
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

S13A3_MOUSE
NC score	0.013100 (rank : 370)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	373	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Y63	Gene names	Slc13a3, Nadc3, Sdct2
Domain Architecture
Description	Solute carrier family 13 member 3 (Sodium-dependent high-affinity dicarboxylate transporter 2) (Na(+)/dicarboxylate cotransporter 3) (NaDC-3) (mNaDC3).

USP9X_MOUSE
NC score	0.013020 (rank : 371)	θ value	1.81305 (rank : 268)
Query Neighborhood Hits	373	Target Neighborhood Hits	171	Shared Neighborhood Hits	11
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

HCFC1_HUMAN
NC score	0.013001 (rank : 372)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	373	Target Neighborhood Hits	331	Shared Neighborhood Hits	30
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

PRGC1_MOUSE
NC score	0.012895 (rank : 373)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	373	Target Neighborhood Hits	238	Shared Neighborhood Hits	16
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

BCL7A_MOUSE
NC score	0.012686 (rank : 374)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	373	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

SEZ6L_HUMAN
NC score	0.012640 (rank : 375)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	373	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

IQEC2_MOUSE
NC score	0.012449 (rank : 376)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	373	Target Neighborhood Hits	417	Shared Neighborhood Hits	43
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

SPEG_HUMAN
NC score	0.012123 (rank : 377)	θ value	1.06291 (rank : 248)
Query Neighborhood Hits	373	Target Neighborhood Hits	1762	Shared Neighborhood Hits	91
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

IASPP_MOUSE
NC score	0.011915 (rank : 378)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	373	Target Neighborhood Hits	1024	Shared Neighborhood Hits	50
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

HCFC1_MOUSE
NC score	0.011665 (rank : 379)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	373	Target Neighborhood Hits	348	Shared Neighborhood Hits	30
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ETV6_HUMAN
NC score	0.011458 (rank : 380)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	373	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

IER5_MOUSE
NC score	0.011373 (rank : 381)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	373	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IQEC2_HUMAN
NC score	0.011128 (rank : 382)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	373	Target Neighborhood Hits	403	Shared Neighborhood Hits	39
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

SPF45_MOUSE
NC score	0.010797 (rank : 383)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	373	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q8JZX4, O75939	Gene names	Rbm17, Spf45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

TEX14_MOUSE
NC score	0.010732 (rank : 384)	θ value	1.81305 (rank : 266)
Query Neighborhood Hits	373	Target Neighborhood Hits	1333	Shared Neighborhood Hits	47
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

SETD8_MOUSE
NC score	0.010612 (rank : 385)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	373	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

CUTL1_MOUSE
NC score	0.010369 (rank : 386)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	373	Target Neighborhood Hits	1620	Shared Neighborhood Hits	75
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TXLNA_HUMAN
NC score	0.010313 (rank : 387)	θ value	8.99809 (rank : 372)
Query Neighborhood Hits	373	Target Neighborhood Hits	982	Shared Neighborhood Hits	49
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

K2C3_HUMAN
NC score	0.010280 (rank : 388)	θ value	1.81305 (rank : 262)
Query Neighborhood Hits	373	Target Neighborhood Hits	443	Shared Neighborhood Hits	17
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

CAC1A_HUMAN
NC score	0.010195 (rank : 389)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	373	Target Neighborhood Hits	387	Shared Neighborhood Hits	41
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

K2C1_MOUSE
NC score	0.009848 (rank : 390)	θ value	1.38821 (rank : 252)
Query Neighborhood Hits	373	Target Neighborhood Hits	477	Shared Neighborhood Hits	22
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

NUMA1_HUMAN
NC score	0.009720 (rank : 391)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	373	Target Neighborhood Hits	1523	Shared Neighborhood Hits	56
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

GGA1_HUMAN
NC score	0.009654 (rank : 392)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	373	Target Neighborhood Hits	169	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

MYO5A_HUMAN
NC score	0.009223 (rank : 393)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	373	Target Neighborhood Hits	1092	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NET2_HUMAN
NC score	0.008949 (rank : 394)	θ value	0.0961366 (rank : 210)
Query Neighborhood Hits	373	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

CYTSA_HUMAN
NC score	0.008865 (rank : 395)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	373	Target Neighborhood Hits	1138	Shared Neighborhood Hits	42
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CALR_HUMAN
NC score	0.008786 (rank : 396)	θ value	2.36792 (rank : 271)
Query Neighborhood Hits	373	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

PAK4_MOUSE
NC score	0.008653 (rank : 397)	θ value	1.38821 (rank : 254)
Query Neighborhood Hits	373	Target Neighborhood Hits	1098	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

HRBL_MOUSE
NC score	0.008155 (rank : 398)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	373	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

PODO_HUMAN
NC score	0.008119 (rank : 399)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	373	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP85, Q8N6Q5	Gene names	NPHS2
Domain Architecture
Description	Podocin.

IKBL_MOUSE
NC score	0.007729 (rank : 400)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	373	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

GLE1_MOUSE
NC score	0.006730 (rank : 401)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	373	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

PRGR_MOUSE
NC score	0.006328 (rank : 402)	θ value	1.81305 (rank : 265)
Query Neighborhood Hits	373	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

MTG8R_HUMAN
NC score	0.006146 (rank : 403)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	373	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

CYTSA_MOUSE
NC score	0.006028 (rank : 404)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	373	Target Neighborhood Hits	1104	Shared Neighborhood Hits	36
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

ANGL6_HUMAN
NC score	0.005776 (rank : 405)	θ value	1.81305 (rank : 258)
Query Neighborhood Hits	373	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

CO3_MOUSE
NC score	0.004029 (rank : 406)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	373	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	P01027, Q61370	Gene names	C3
Domain Architecture
Description	Complement C3 precursor (HSE-MSF) [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3, isoform Short; Complement C3f fragment].

TRI32_MOUSE
NC score	0.003198 (rank : 407)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	373	Target Neighborhood Hits	271	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

AATK_MOUSE
NC score	0.002618 (rank : 408)	θ value	1.38821 (rank : 250)
Query Neighborhood Hits	373	Target Neighborhood Hits	942	Shared Neighborhood Hits	40
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

PCOC1_HUMAN
NC score	0.002237 (rank : 409)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	373	Target Neighborhood Hits	146	Shared Neighborhood Hits	10
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

KCNQ1_HUMAN
NC score	0.001926 (rank : 410)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	373	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

ROBO1_MOUSE
NC score	0.001875 (rank : 411)	θ value	1.38821 (rank : 256)
Query Neighborhood Hits	373	Target Neighborhood Hits	559	Shared Neighborhood Hits	21
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ABL2_HUMAN
NC score	0.001090 (rank : 412)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	373	Target Neighborhood Hits	1045	Shared Neighborhood Hits	27
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

EPHB3_MOUSE
NC score	0.000734 (rank : 413)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	373	Target Neighborhood Hits	996	Shared Neighborhood Hits	26
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

DGKB_HUMAN
NC score	0.000524 (rank : 414)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	373	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

INVS_HUMAN
NC score	-0.000260 (rank : 415)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	373	Target Neighborhood Hits	455	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

KLH14_HUMAN
NC score	-0.001004 (rank : 416)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	373	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2G3	Gene names	KLHL14, KIAA1384
Domain Architecture	No domain graphic available
Description	Kelch-like protein 14.

NOTC1_MOUSE
NC score	-0.005445 (rank : 417)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	373	Target Neighborhood Hits	916	Shared Neighborhood Hits	21
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CELR1_MOUSE
NC score	-0.005971 (rank : 418)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	373	Target Neighborhood Hits	617	Shared Neighborhood Hits	7
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

ZBTB9_HUMAN
NC score	-0.006255 (rank : 419)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	373	Target Neighborhood Hits	764	Shared Neighborhood Hits	10
SwissProt Accessions	Q96C00	Gene names	ZBTB9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

ZN335_HUMAN
NC score	-0.007027 (rank : 420)	θ value	1.81305 (rank : 270)
Query Neighborhood Hits	373	Target Neighborhood Hits	973	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

5HT7R_MOUSE
NC score	-0.008024 (rank : 421)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	373	Target Neighborhood Hits	823	Shared Neighborhood Hits	3
SwissProt Accessions	P32304	Gene names	Htr7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

5HT7R_HUMAN
NC score	-0.008283 (rank : 422)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	373	Target Neighborhood Hits	848	Shared Neighborhood Hits	3
SwissProt Accessions	P34969, P78336, P78372, P78516	Gene names	HTR7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

PRD16_HUMAN
NC score	-0.008290 (rank : 423)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	373	Target Neighborhood Hits	832	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

ZN202_HUMAN
NC score	-0.009048 (rank : 424)	θ value	1.81305 (rank : 269)
Query Neighborhood Hits	373	Target Neighborhood Hits	756	Shared Neighborhood Hits	13
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

HKR3_HUMAN
NC score	-0.009228 (rank : 425)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	373	Target Neighborhood Hits	839	Shared Neighborhood Hits	11
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).