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Network neighborhood for query Sequence : RIMS1_HUMAN

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RIMS1_HUMAN
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIMS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	437	Target Neighborhood Hits	437	Shared Neighborhood Hits	437
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIMS2_HUMAN
θ value	0 (rank : 2)	NC score	0.943046 (rank : 2)
Query Neighborhood Hits	437	Target Neighborhood Hits	342	Shared Neighborhood Hits	228
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0 (rank : 3)	NC score	0.940040 (rank : 3)
Query Neighborhood Hits	437	Target Neighborhood Hits	376	Shared Neighborhood Hits	230
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS3_HUMAN
θ value	1.64657e-102 (rank : 4)	NC score	0.856445 (rank : 6)
Query Neighborhood Hits	437	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	4.79078e-102 (rank : 5)	NC score	0.851146 (rank : 7)
Query Neighborhood Hits	437	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS4_MOUSE
θ value	4.81303e-86 (rank : 6)	NC score	0.871401 (rank : 4)
Query Neighborhood Hits	437	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
θ value	8.20983e-86 (rank : 7)	NC score	0.870825 (rank : 5)
Query Neighborhood Hits	437	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

PCLO_MOUSE
θ value	1.57365e-28 (rank : 8)	NC score	0.552841 (rank : 32)
Query Neighborhood Hits	437	Target Neighborhood Hits	2275	Shared Neighborhood Hits	299
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCLO_HUMAN
θ value	2.77775e-25 (rank : 9)	NC score	0.519112 (rank : 49)
Query Neighborhood Hits	437	Target Neighborhood Hits	2046	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

P3C2B_HUMAN
θ value	5.43371e-13 (rank : 10)	NC score	0.449884 (rank : 53)
Query Neighborhood Hits	437	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

SYTL4_MOUSE
θ value	9.26847e-13 (rank : 11)	NC score	0.594376 (rank : 13)
Query Neighborhood Hits	437	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_HUMAN
θ value	1.58096e-12 (rank : 12)	NC score	0.596956 (rank : 9)
Query Neighborhood Hits	437	Target Neighborhood Hits	138	Shared Neighborhood Hits	85
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYT3_HUMAN
θ value	4.59992e-12 (rank : 13)	NC score	0.571826 (rank : 21)
Query Neighborhood Hits	437	Target Neighborhood Hits	145	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

DOC2A_MOUSE
θ value	7.84624e-12 (rank : 14)	NC score	0.595713 (rank : 10)
Query Neighborhood Hits	437	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

P3C2A_HUMAN
θ value	1.33837e-11 (rank : 15)	NC score	0.400784 (rank : 55)
Query Neighborhood Hits	437	Target Neighborhood Hits	188	Shared Neighborhood Hits	79
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
θ value	2.28291e-11 (rank : 16)	NC score	0.395278 (rank : 56)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	77
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

SYT2_MOUSE
θ value	2.28291e-11 (rank : 17)	NC score	0.558894 (rank : 27)
Query Neighborhood Hits	437	Target Neighborhood Hits	143	Shared Neighborhood Hits	99
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT3_MOUSE
θ value	2.28291e-11 (rank : 18)	NC score	0.567906 (rank : 24)
Query Neighborhood Hits	437	Target Neighborhood Hits	147	Shared Neighborhood Hits	95
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYTL1_HUMAN
θ value	2.28291e-11 (rank : 19)	NC score	0.600015 (rank : 8)
Query Neighborhood Hits	437	Target Neighborhood Hits	227	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYT2_HUMAN
θ value	2.98157e-11 (rank : 20)	NC score	0.558650 (rank : 28)
Query Neighborhood Hits	437	Target Neighborhood Hits	142	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYTL5_HUMAN
θ value	3.89403e-11 (rank : 21)	NC score	0.594561 (rank : 12)
Query Neighborhood Hits	437	Target Neighborhood Hits	237	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT9_MOUSE
θ value	5.08577e-11 (rank : 22)	NC score	0.553954 (rank : 31)
Query Neighborhood Hits	437	Target Neighborhood Hits	148	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

DOC2A_HUMAN
θ value	6.64225e-11 (rank : 23)	NC score	0.592815 (rank : 14)
Query Neighborhood Hits	437	Target Neighborhood Hits	144	Shared Neighborhood Hits	97
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYTL1_MOUSE
θ value	8.67504e-11 (rank : 24)	NC score	0.571731 (rank : 22)
Query Neighborhood Hits	437	Target Neighborhood Hits	314	Shared Neighborhood Hits	93
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

DOC2B_HUMAN
θ value	1.133e-10 (rank : 25)	NC score	0.584337 (rank : 16)
Query Neighborhood Hits	437	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
θ value	1.133e-10 (rank : 26)	NC score	0.582973 (rank : 18)
Query Neighborhood Hits	437	Target Neighborhood Hits	169	Shared Neighborhood Hits	100
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

KPCA_HUMAN
θ value	1.133e-10 (rank : 27)	NC score	0.169489 (rank : 186)
Query Neighborhood Hits	437	Target Neighborhood Hits	1070	Shared Neighborhood Hits	115
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

RP3A_HUMAN
θ value	1.47974e-10 (rank : 28)	NC score	0.587796 (rank : 15)
Query Neighborhood Hits	437	Target Neighborhood Hits	305	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

FA62A_HUMAN
θ value	1.9326e-10 (rank : 29)	NC score	0.543376 (rank : 39)
Query Neighborhood Hits	437	Target Neighborhood Hits	168	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYTL2_MOUSE
θ value	1.9326e-10 (rank : 30)	NC score	0.561191 (rank : 26)
Query Neighborhood Hits	437	Target Neighborhood Hits	253	Shared Neighborhood Hits	109
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL5_MOUSE
θ value	1.9326e-10 (rank : 31)	NC score	0.583815 (rank : 17)
Query Neighborhood Hits	437	Target Neighborhood Hits	154	Shared Neighborhood Hits	97
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

KPCB_HUMAN
θ value	3.29651e-10 (rank : 32)	NC score	0.165939 (rank : 189)
Query Neighborhood Hits	437	Target Neighborhood Hits	1121	Shared Neighborhood Hits	115
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

RP3A_MOUSE
θ value	3.29651e-10 (rank : 33)	NC score	0.575067 (rank : 20)
Query Neighborhood Hits	437	Target Neighborhood Hits	510	Shared Neighborhood Hits	130
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

KPCA_MOUSE
θ value	4.30538e-10 (rank : 34)	NC score	0.165344 (rank : 191)
Query Neighborhood Hits	437	Target Neighborhood Hits	1067	Shared Neighborhood Hits	115
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SYT10_HUMAN
θ value	4.30538e-10 (rank : 35)	NC score	0.549392 (rank : 34)
Query Neighborhood Hits	437	Target Neighborhood Hits	134	Shared Neighborhood Hits	97
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

KPCB_MOUSE
θ value	5.62301e-10 (rank : 36)	NC score	0.166814 (rank : 188)
Query Neighborhood Hits	437	Target Neighborhood Hits	1117	Shared Neighborhood Hits	114
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCG_MOUSE
θ value	5.62301e-10 (rank : 37)	NC score	0.180214 (rank : 172)
Query Neighborhood Hits	437	Target Neighborhood Hits	1123	Shared Neighborhood Hits	113
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT6_MOUSE
θ value	7.34386e-10 (rank : 38)	NC score	0.555348 (rank : 29)
Query Neighborhood Hits	437	Target Neighborhood Hits	132	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT9_HUMAN
θ value	7.34386e-10 (rank : 39)	NC score	0.550947 (rank : 33)
Query Neighborhood Hits	437	Target Neighborhood Hits	144	Shared Neighborhood Hits	98
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYTL2_HUMAN
θ value	9.59137e-10 (rank : 40)	NC score	0.566108 (rank : 25)
Query Neighborhood Hits	437	Target Neighborhood Hits	248	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

KPCG_HUMAN
θ value	1.25267e-09 (rank : 41)	NC score	0.179361 (rank : 175)
Query Neighborhood Hits	437	Target Neighborhood Hits	1126	Shared Neighborhood Hits	113
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT1_HUMAN
θ value	1.25267e-09 (rank : 42)	NC score	0.548262 (rank : 35)
Query Neighborhood Hits	437	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	1.25267e-09 (rank : 43)	NC score	0.548248 (rank : 36)
Query Neighborhood Hits	437	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT6_HUMAN
θ value	1.25267e-09 (rank : 44)	NC score	0.554373 (rank : 30)
Query Neighborhood Hits	437	Target Neighborhood Hits	138	Shared Neighborhood Hits	98
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT7_MOUSE
θ value	1.63604e-09 (rank : 45)	NC score	0.581318 (rank : 19)
Query Neighborhood Hits	437	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT10_MOUSE
θ value	2.13673e-09 (rank : 46)	NC score	0.547302 (rank : 37)
Query Neighborhood Hits	437	Target Neighborhood Hits	133	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT7_HUMAN
θ value	2.79066e-09 (rank : 47)	NC score	0.568479 (rank : 23)
Query Neighborhood Hits	437	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SRRM2_MOUSE
θ value	2.36244e-08 (rank : 48)	NC score	0.179607 (rank : 174)
Query Neighborhood Hits	437	Target Neighborhood Hits	1470	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYT5_MOUSE
θ value	3.08544e-08 (rank : 49)	NC score	0.535291 (rank : 42)
Query Neighborhood Hits	437	Target Neighborhood Hits	140	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYTL3_MOUSE
θ value	4.0297e-08 (rank : 50)	NC score	0.595288 (rank : 11)
Query Neighborhood Hits	437	Target Neighborhood Hits	110	Shared Neighborhood Hits	81
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

FA62A_MOUSE
θ value	8.97725e-08 (rank : 51)	NC score	0.541624 (rank : 40)
Query Neighborhood Hits	437	Target Neighborhood Hits	155	Shared Neighborhood Hits	97
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT5_HUMAN
θ value	1.17247e-07 (rank : 52)	NC score	0.540879 (rank : 41)
Query Neighborhood Hits	437	Target Neighborhood Hits	138	Shared Neighborhood Hits	98
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT4_HUMAN
θ value	1.99992e-07 (rank : 53)	NC score	0.530474 (rank : 43)
Query Neighborhood Hits	437	Target Neighborhood Hits	121	Shared Neighborhood Hits	95
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

NFH_MOUSE
θ value	3.41135e-07 (rank : 54)	NC score	0.072891 (rank : 325)
Query Neighborhood Hits	437	Target Neighborhood Hits	2247	Shared Neighborhood Hits	165
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SYT4_MOUSE
θ value	5.81887e-07 (rank : 55)	NC score	0.523947 (rank : 46)
Query Neighborhood Hits	437	Target Neighborhood Hits	123	Shared Neighborhood Hits	92
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

DOC2G_MOUSE
θ value	9.92553e-07 (rank : 56)	NC score	0.543570 (rank : 38)
Query Neighborhood Hits	437	Target Neighborhood Hits	125	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT11_MOUSE
θ value	9.92553e-07 (rank : 57)	NC score	0.523892 (rank : 47)
Query Neighborhood Hits	437	Target Neighborhood Hits	116	Shared Neighborhood Hits	92
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

RASL2_HUMAN
θ value	1.29631e-06 (rank : 58)	NC score	0.421927 (rank : 54)
Query Neighborhood Hits	437	Target Neighborhood Hits	161	Shared Neighborhood Hits	92
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

P3C2G_MOUSE
θ value	3.77169e-06 (rank : 59)	NC score	0.244867 (rank : 93)
Query Neighborhood Hits	437	Target Neighborhood Hits	113	Shared Neighborhood Hits	63
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

SYT12_MOUSE
θ value	3.77169e-06 (rank : 60)	NC score	0.524316 (rank : 45)
Query Neighborhood Hits	437	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT11_HUMAN
θ value	4.92598e-06 (rank : 61)	NC score	0.522455 (rank : 48)
Query Neighborhood Hits	437	Target Neighborhood Hits	113	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT12_HUMAN
θ value	8.40245e-06 (rank : 62)	NC score	0.524319 (rank : 44)
Query Neighborhood Hits	437	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

MPDZ_HUMAN
θ value	1.09739e-05 (rank : 63)	NC score	0.281669 (rank : 71)
Query Neighborhood Hits	437	Target Neighborhood Hits	261	Shared Neighborhood Hits	129
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

UN13B_HUMAN
θ value	1.09739e-05 (rank : 64)	NC score	0.301013 (rank : 67)
Query Neighborhood Hits	437	Target Neighborhood Hits	217	Shared Neighborhood Hits	84
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

WHRN_MOUSE
θ value	1.09739e-05 (rank : 65)	NC score	0.274470 (rank : 77)
Query Neighborhood Hits	437	Target Neighborhood Hits	412	Shared Neighborhood Hits	138
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PTN13_HUMAN
θ value	1.43324e-05 (rank : 66)	NC score	0.172937 (rank : 183)
Query Neighborhood Hits	437	Target Neighborhood Hits	471	Shared Neighborhood Hits	146
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

UN13B_MOUSE
θ value	1.43324e-05 (rank : 67)	NC score	0.302854 (rank : 65)
Query Neighborhood Hits	437	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

SYT15_HUMAN
θ value	2.44474e-05 (rank : 68)	NC score	0.504000 (rank : 50)
Query Neighborhood Hits	437	Target Neighborhood Hits	112	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

TXND2_HUMAN
θ value	3.19293e-05 (rank : 69)	NC score	0.101997 (rank : 267)
Query Neighborhood Hits	437	Target Neighborhood Hits	793	Shared Neighborhood Hits	87
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UN13A_HUMAN
θ value	3.19293e-05 (rank : 70)	NC score	0.306633 (rank : 64)
Query Neighborhood Hits	437	Target Neighborhood Hits	285	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

P3C2G_HUMAN
θ value	4.1701e-05 (rank : 71)	NC score	0.219602 (rank : 129)
Query Neighborhood Hits	437	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PDZD2_HUMAN
θ value	4.1701e-05 (rank : 72)	NC score	0.295567 (rank : 68)
Query Neighborhood Hits	437	Target Neighborhood Hits	772	Shared Neighborhood Hits	176
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

WHRN_HUMAN
θ value	4.1701e-05 (rank : 73)	NC score	0.270579 (rank : 79)
Query Neighborhood Hits	437	Target Neighborhood Hits	325	Shared Neighborhood Hits	134
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

INADL_HUMAN
θ value	7.1131e-05 (rank : 74)	NC score	0.278114 (rank : 75)
Query Neighborhood Hits	437	Target Neighborhood Hits	260	Shared Neighborhood Hits	127
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

SNTA1_HUMAN
θ value	9.29e-05 (rank : 75)	NC score	0.238401 (rank : 96)
Query Neighborhood Hits	437	Target Neighborhood Hits	186	Shared Neighborhood Hits	111
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

USH1C_HUMAN
θ value	9.29e-05 (rank : 76)	NC score	0.282452 (rank : 70)
Query Neighborhood Hits	437	Target Neighborhood Hits	327	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	9.29e-05 (rank : 77)	NC score	0.271461 (rank : 78)
Query Neighborhood Hits	437	Target Neighborhood Hits	557	Shared Neighborhood Hits	145
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PTN13_MOUSE
θ value	0.000121331 (rank : 78)	NC score	0.165887 (rank : 190)
Query Neighborhood Hits	437	Target Neighborhood Hits	426	Shared Neighborhood Hits	139
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

RGS3_HUMAN
θ value	0.000121331 (rank : 79)	NC score	0.220285 (rank : 127)
Query Neighborhood Hits	437	Target Neighborhood Hits	1375	Shared Neighborhood Hits	164
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SYT15_MOUSE
θ value	0.000121331 (rank : 80)	NC score	0.469075 (rank : 52)
Query Neighborhood Hits	437	Target Neighborhood Hits	100	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

INADL_MOUSE
θ value	0.000158464 (rank : 81)	NC score	0.277073 (rank : 76)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	132
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

SRRM2_HUMAN
θ value	0.000158464 (rank : 82)	NC score	0.170921 (rank : 185)
Query Neighborhood Hits	437	Target Neighborhood Hits	1296	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ZO3_MOUSE
θ value	0.000158464 (rank : 83)	NC score	0.216405 (rank : 130)
Query Neighborhood Hits	437	Target Neighborhood Hits	224	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

NED4L_HUMAN
θ value	0.00020696 (rank : 84)	NC score	0.258811 (rank : 85)
Query Neighborhood Hits	437	Target Neighborhood Hits	238	Shared Neighborhood Hits	99
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	0.00020696 (rank : 85)	NC score	0.253875 (rank : 87)
Query Neighborhood Hits	437	Target Neighborhood Hits	231	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

MPDZ_MOUSE
θ value	0.000270298 (rank : 86)	NC score	0.278898 (rank : 74)
Query Neighborhood Hits	437	Target Neighborhood Hits	298	Shared Neighborhood Hits	131
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PARD3_HUMAN
θ value	0.00035302 (rank : 87)	NC score	0.267976 (rank : 83)
Query Neighborhood Hits	437	Target Neighborhood Hits	312	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

TGON2_HUMAN
θ value	0.00035302 (rank : 88)	NC score	0.104399 (rank : 263)
Query Neighborhood Hits	437	Target Neighborhood Hits	1037	Shared Neighborhood Hits	118
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

DLG2_MOUSE
θ value	0.000461057 (rank : 89)	NC score	0.235507 (rank : 101)
Query Neighborhood Hits	437	Target Neighborhood Hits	271	Shared Neighborhood Hits	127
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

GOPC_MOUSE
θ value	0.000461057 (rank : 90)	NC score	0.231539 (rank : 107)
Query Neighborhood Hits	437	Target Neighborhood Hits	323	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

DLG2_HUMAN
θ value	0.000602161 (rank : 91)	NC score	0.234387 (rank : 104)
Query Neighborhood Hits	437	Target Neighborhood Hits	279	Shared Neighborhood Hits	129
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

SNTA1_MOUSE
θ value	0.000786445 (rank : 92)	NC score	0.226116 (rank : 113)
Query Neighborhood Hits	437	Target Neighborhood Hits	170	Shared Neighborhood Hits	107
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

NIPBL_HUMAN
θ value	0.00102713 (rank : 93)	NC score	0.119445 (rank : 237)
Query Neighborhood Hits	437	Target Neighborhood Hits	1311	Shared Neighborhood Hits	138
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

DLG3_HUMAN
θ value	0.00134147 (rank : 94)	NC score	0.225708 (rank : 116)
Query Neighborhood Hits	437	Target Neighborhood Hits	269	Shared Neighborhood Hits	123
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	0.00134147 (rank : 95)	NC score	0.226369 (rank : 111)
Query Neighborhood Hits	437	Target Neighborhood Hits	274	Shared Neighborhood Hits	123
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

IWS1_MOUSE
θ value	0.00134147 (rank : 96)	NC score	0.097036 (rank : 275)
Query Neighborhood Hits	437	Target Neighborhood Hits	1258	Shared Neighborhood Hits	119
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PARD3_MOUSE
θ value	0.00175202 (rank : 97)	NC score	0.266829 (rank : 84)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	134
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

TCAL5_HUMAN
θ value	0.00175202 (rank : 98)	NC score	0.067054 (rank : 350)
Query Neighborhood Hits	437	Target Neighborhood Hits	806	Shared Neighborhood Hits	71
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

PAR3L_HUMAN
θ value	0.00228821 (rank : 99)	NC score	0.268044 (rank : 82)
Query Neighborhood Hits	437	Target Neighborhood Hits	297	Shared Neighborhood Hits	122
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PZRN4_HUMAN
θ value	0.00228821 (rank : 100)	NC score	0.192150 (rank : 152)
Query Neighborhood Hits	437	Target Neighborhood Hits	438	Shared Neighborhood Hits	117
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

DLG4_HUMAN
θ value	0.00298849 (rank : 101)	NC score	0.234755 (rank : 103)
Query Neighborhood Hits	437	Target Neighborhood Hits	286	Shared Neighborhood Hits	120
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	0.00298849 (rank : 102)	NC score	0.235185 (rank : 102)
Query Neighborhood Hits	437	Target Neighborhood Hits	282	Shared Neighborhood Hits	121
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

GOPC_HUMAN
θ value	0.00298849 (rank : 103)	NC score	0.224753 (rank : 117)
Query Neighborhood Hits	437	Target Neighborhood Hits	377	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

LNX2_MOUSE
θ value	0.00390308 (rank : 104)	NC score	0.238471 (rank : 95)
Query Neighborhood Hits	437	Target Neighborhood Hits	407	Shared Neighborhood Hits	125
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PA24B_HUMAN
θ value	0.00390308 (rank : 105)	NC score	0.203268 (rank : 141)
Query Neighborhood Hits	437	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

DLG1_MOUSE
θ value	0.00509761 (rank : 106)	NC score	0.227192 (rank : 109)
Query Neighborhood Hits	437	Target Neighborhood Hits	285	Shared Neighborhood Hits	122
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

LAP4_HUMAN
θ value	0.00509761 (rank : 107)	NC score	0.162430 (rank : 193)
Query Neighborhood Hits	437	Target Neighborhood Hits	608	Shared Neighborhood Hits	140
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
θ value	0.00509761 (rank : 108)	NC score	0.160497 (rank : 197)
Query Neighborhood Hits	437	Target Neighborhood Hits	590	Shared Neighborhood Hits	142
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LNX2_HUMAN
θ value	0.00509761 (rank : 109)	NC score	0.238899 (rank : 94)
Query Neighborhood Hits	437	Target Neighborhood Hits	389	Shared Neighborhood Hits	120
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

SNTB1_MOUSE
θ value	0.00509761 (rank : 110)	NC score	0.223324 (rank : 120)
Query Neighborhood Hits	437	Target Neighborhood Hits	160	Shared Neighborhood Hits	102
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SYT8_MOUSE
θ value	0.00509761 (rank : 111)	NC score	0.487569 (rank : 51)
Query Neighborhood Hits	437	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

DLG1_HUMAN
θ value	0.00665767 (rank : 112)	NC score	0.227252 (rank : 108)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	124
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

K1849_MOUSE
θ value	0.00665767 (rank : 113)	NC score	0.205113 (rank : 139)
Query Neighborhood Hits	437	Target Neighborhood Hits	335	Shared Neighborhood Hits	121
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

NEB1_HUMAN
θ value	0.00665767 (rank : 114)	NC score	0.174085 (rank : 181)
Query Neighborhood Hits	437	Target Neighborhood Hits	829	Shared Neighborhood Hits	145
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SNTG2_HUMAN
θ value	0.00665767 (rank : 115)	NC score	0.232570 (rank : 106)
Query Neighborhood Hits	437	Target Neighborhood Hits	191	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

APBA2_MOUSE
θ value	0.00869519 (rank : 116)	NC score	0.151659 (rank : 206)
Query Neighborhood Hits	437	Target Neighborhood Hits	219	Shared Neighborhood Hits	113
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

NPBL_MOUSE
θ value	0.00869519 (rank : 117)	NC score	0.114089 (rank : 241)
Query Neighborhood Hits	437	Target Neighborhood Hits	1041	Shared Neighborhood Hits	117
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PICK1_MOUSE
θ value	0.00869519 (rank : 118)	NC score	0.199757 (rank : 146)
Query Neighborhood Hits	437	Target Neighborhood Hits	131	Shared Neighborhood Hits	101
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

GRIP2_HUMAN
θ value	0.0113563 (rank : 119)	NC score	0.233817 (rank : 105)
Query Neighborhood Hits	437	Target Neighborhood Hits	256	Shared Neighborhood Hits	133
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

NHRF2_MOUSE
θ value	0.0113563 (rank : 120)	NC score	0.191218 (rank : 155)
Query Neighborhood Hits	437	Target Neighborhood Hits	194	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

RASL1_HUMAN
θ value	0.0113563 (rank : 121)	NC score	0.321808 (rank : 62)
Query Neighborhood Hits	437	Target Neighborhood Hits	142	Shared Neighborhood Hits	80
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

SNTB2_HUMAN
θ value	0.0113563 (rank : 122)	NC score	0.226041 (rank : 114)
Query Neighborhood Hits	437	Target Neighborhood Hits	180	Shared Neighborhood Hits	107
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

INVS_MOUSE
θ value	0.0148317 (rank : 123)	NC score	0.025205 (rank : 514)
Query Neighborhood Hits	437	Target Neighborhood Hits	609	Shared Neighborhood Hits	41
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

LNX1_MOUSE
θ value	0.0148317 (rank : 124)	NC score	0.236393 (rank : 98)
Query Neighborhood Hits	437	Target Neighborhood Hits	377	Shared Neighborhood Hits	124
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

NEDD4_HUMAN
θ value	0.0148317 (rank : 125)	NC score	0.235665 (rank : 100)
Query Neighborhood Hits	437	Target Neighborhood Hits	214	Shared Neighborhood Hits	97
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

TARA_MOUSE
θ value	0.0148317 (rank : 126)	NC score	0.080491 (rank : 309)
Query Neighborhood Hits	437	Target Neighborhood Hits	1133	Shared Neighborhood Hits	94
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DLG5_HUMAN
θ value	0.0193708 (rank : 127)	NC score	0.159576 (rank : 199)
Query Neighborhood Hits	437	Target Neighborhood Hits	1088	Shared Neighborhood Hits	143
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

IL16_HUMAN
θ value	0.0193708 (rank : 128)	NC score	0.269004 (rank : 81)
Query Neighborhood Hits	437	Target Neighborhood Hits	207	Shared Neighborhood Hits	119
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

ITSN2_HUMAN
θ value	0.0193708 (rank : 129)	NC score	0.140471 (rank : 216)
Query Neighborhood Hits	437	Target Neighborhood Hits	1173	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

IWS1_HUMAN
θ value	0.0193708 (rank : 130)	NC score	0.100320 (rank : 270)
Query Neighborhood Hits	437	Target Neighborhood Hits	1241	Shared Neighborhood Hits	122
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PICK1_HUMAN
θ value	0.0193708 (rank : 131)	NC score	0.201983 (rank : 142)
Query Neighborhood Hits	437	Target Neighborhood Hits	132	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

RBBP5_HUMAN
θ value	0.0193708 (rank : 132)	NC score	0.036301 (rank : 478)
Query Neighborhood Hits	437	Target Neighborhood Hits	372	Shared Neighborhood Hits	17
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

BRWD1_MOUSE
θ value	0.0252991 (rank : 133)	NC score	0.017252 (rank : 542)
Query Neighborhood Hits	437	Target Neighborhood Hits	478	Shared Neighborhood Hits	34
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

K1849_HUMAN
θ value	0.0252991 (rank : 134)	NC score	0.196631 (rank : 149)
Query Neighborhood Hits	437	Target Neighborhood Hits	220	Shared Neighborhood Hits	112
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PAR6G_HUMAN
θ value	0.0252991 (rank : 135)	NC score	0.197999 (rank : 148)
Query Neighborhood Hits	437	Target Neighborhood Hits	159	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PZRN3_MOUSE
θ value	0.0252991 (rank : 136)	NC score	0.190464 (rank : 157)
Query Neighborhood Hits	437	Target Neighborhood Hits	447	Shared Neighborhood Hits	124
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TARA_HUMAN
θ value	0.0252991 (rank : 137)	NC score	0.098839 (rank : 272)
Query Neighborhood Hits	437	Target Neighborhood Hits	1626	Shared Neighborhood Hits	131
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FA47A_HUMAN
θ value	0.0330416 (rank : 138)	NC score	0.100627 (rank : 269)
Query Neighborhood Hits	437	Target Neighborhood Hits	451	Shared Neighborhood Hits	50
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

ITSN1_HUMAN
θ value	0.0330416 (rank : 139)	NC score	0.109611 (rank : 249)
Query Neighborhood Hits	437	Target Neighborhood Hits	1757	Shared Neighborhood Hits	146
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	0.0330416 (rank : 140)	NC score	0.111676 (rank : 244)
Query Neighborhood Hits	437	Target Neighborhood Hits	1669	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NHRF2_HUMAN
θ value	0.0330416 (rank : 141)	NC score	0.191326 (rank : 154)
Query Neighborhood Hits	437	Target Neighborhood Hits	197	Shared Neighborhood Hits	109
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

CUTL1_MOUSE
θ value	0.0431538 (rank : 142)	NC score	0.030441 (rank : 496)
Query Neighborhood Hits	437	Target Neighborhood Hits	1620	Shared Neighborhood Hits	81
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DCC_HUMAN
θ value	0.0431538 (rank : 143)	NC score	0.016068 (rank : 548)
Query Neighborhood Hits	437	Target Neighborhood Hits	583	Shared Neighborhood Hits	17
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

IL16_MOUSE
θ value	0.0431538 (rank : 144)	NC score	0.255012 (rank : 86)
Query Neighborhood Hits	437	Target Neighborhood Hits	189	Shared Neighborhood Hits	108
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LIN7B_HUMAN
θ value	0.0431538 (rank : 145)	NC score	0.251415 (rank : 88)
Query Neighborhood Hits	437	Target Neighborhood Hits	200	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

NEB2_HUMAN
θ value	0.0431538 (rank : 146)	NC score	0.151160 (rank : 207)
Query Neighborhood Hits	437	Target Neighborhood Hits	883	Shared Neighborhood Hits	132
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	0.0431538 (rank : 147)	NC score	0.152639 (rank : 204)
Query Neighborhood Hits	437	Target Neighborhood Hits	889	Shared Neighborhood Hits	135
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PA24B_MOUSE
θ value	0.0431538 (rank : 148)	NC score	0.223189 (rank : 121)
Query Neighborhood Hits	437	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

RPGR1_MOUSE
θ value	0.0431538 (rank : 149)	NC score	0.057006 (rank : 393)
Query Neighborhood Hits	437	Target Neighborhood Hits	713	Shared Neighborhood Hits	62
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SNTB2_MOUSE
θ value	0.0431538 (rank : 150)	NC score	0.224497 (rank : 118)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	106
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

ALO17_HUMAN
θ value	0.0563607 (rank : 151)	NC score	0.072227 (rank : 328)
Query Neighborhood Hits	437	Target Neighborhood Hits	317	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ARI2_HUMAN
θ value	0.0563607 (rank : 152)	NC score	0.034620 (rank : 485)
Query Neighborhood Hits	437	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	0.0563607 (rank : 153)	NC score	0.034733 (rank : 484)
Query Neighborhood Hits	437	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

DCC_MOUSE
θ value	0.0563607 (rank : 154)	NC score	0.019998 (rank : 530)
Query Neighborhood Hits	437	Target Neighborhood Hits	896	Shared Neighborhood Hits	34
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

LIN7B_MOUSE
θ value	0.0563607 (rank : 155)	NC score	0.249905 (rank : 89)
Query Neighborhood Hits	437	Target Neighborhood Hits	200	Shared Neighborhood Hits	123
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LNX1_HUMAN
θ value	0.0563607 (rank : 156)	NC score	0.221161 (rank : 124)
Query Neighborhood Hits	437	Target Neighborhood Hits	379	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PAR6A_HUMAN
θ value	0.0563607 (rank : 157)	NC score	0.192385 (rank : 151)
Query Neighborhood Hits	437	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	0.0563607 (rank : 158)	NC score	0.191933 (rank : 153)
Query Neighborhood Hits	437	Target Neighborhood Hits	115	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PZRN3_HUMAN
θ value	0.0563607 (rank : 159)	NC score	0.188427 (rank : 159)
Query Neighborhood Hits	437	Target Neighborhood Hits	461	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RASL1_MOUSE
θ value	0.0563607 (rank : 160)	NC score	0.308454 (rank : 63)
Query Neighborhood Hits	437	Target Neighborhood Hits	148	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

SON_HUMAN
θ value	0.0563607 (rank : 161)	NC score	0.061475 (rank : 376)
Query Neighborhood Hits	437	Target Neighborhood Hits	1568	Shared Neighborhood Hits	100
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

VRK3_HUMAN
θ value	0.0563607 (rank : 162)	NC score	0.029521 (rank : 499)
Query Neighborhood Hits	437	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

CHD9_MOUSE
θ value	0.0736092 (rank : 163)	NC score	0.028138 (rank : 504)
Query Neighborhood Hits	437	Target Neighborhood Hits	427	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CUTL1_HUMAN
θ value	0.0736092 (rank : 164)	NC score	0.028098 (rank : 505)
Query Neighborhood Hits	437	Target Neighborhood Hits	1574	Shared Neighborhood Hits	80
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

E41L2_MOUSE
θ value	0.0736092 (rank : 165)	NC score	0.032607 (rank : 489)
Query Neighborhood Hits	437	Target Neighborhood Hits	459	Shared Neighborhood Hits	49
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

GIPC1_MOUSE
θ value	0.0736092 (rank : 166)	NC score	0.139418 (rank : 219)
Query Neighborhood Hits	437	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

ITSN2_MOUSE
θ value	0.0736092 (rank : 167)	NC score	0.128129 (rank : 227)
Query Neighborhood Hits	437	Target Neighborhood Hits	1371	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

NEDD4_MOUSE
θ value	0.0736092 (rank : 168)	NC score	0.220883 (rank : 125)
Query Neighborhood Hits	437	Target Neighborhood Hits	212	Shared Neighborhood Hits	96
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

PAR6G_MOUSE
θ value	0.0736092 (rank : 169)	NC score	0.199826 (rank : 145)
Query Neighborhood Hits	437	Target Neighborhood Hits	121	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

SYT14_MOUSE
θ value	0.0736092 (rank : 170)	NC score	0.374994 (rank : 57)
Query Neighborhood Hits	437	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

UN13D_HUMAN
θ value	0.0736092 (rank : 171)	NC score	0.347284 (rank : 61)
Query Neighborhood Hits	437	Target Neighborhood Hits	117	Shared Neighborhood Hits	80
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

BSN_MOUSE
θ value	0.0961366 (rank : 172)	NC score	0.115964 (rank : 240)
Query Neighborhood Hits	437	Target Neighborhood Hits	2057	Shared Neighborhood Hits	121
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GIPC1_HUMAN
θ value	0.0961366 (rank : 173)	NC score	0.134694 (rank : 223)
Query Neighborhood Hits	437	Target Neighborhood Hits	91	Shared Neighborhood Hits	68
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

JARD2_MOUSE
θ value	0.0961366 (rank : 174)	NC score	0.037175 (rank : 473)
Query Neighborhood Hits	437	Target Neighborhood Hits	169	Shared Neighborhood Hits	28
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

KCD18_HUMAN
θ value	0.0961366 (rank : 175)	NC score	0.036879 (rank : 475)
Query Neighborhood Hits	437	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

MAGI1_MOUSE
θ value	0.0961366 (rank : 176)	NC score	0.224093 (rank : 119)
Query Neighborhood Hits	437	Target Neighborhood Hits	403	Shared Neighborhood Hits	158
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MPP5_HUMAN
θ value	0.0961366 (rank : 177)	NC score	0.160631 (rank : 196)
Query Neighborhood Hits	437	Target Neighborhood Hits	231	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.0961366 (rank : 178)	NC score	0.159922 (rank : 198)
Query Neighborhood Hits	437	Target Neighborhood Hits	226	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PA24A_HUMAN
θ value	0.0961366 (rank : 179)	NC score	0.186161 (rank : 162)
Query Neighborhood Hits	437	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24A_MOUSE
θ value	0.0961366 (rank : 180)	NC score	0.193782 (rank : 150)
Query Neighborhood Hits	437	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24D_MOUSE
θ value	0.0961366 (rank : 181)	NC score	0.270491 (rank : 80)
Query Neighborhood Hits	437	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PDZD7_HUMAN
θ value	0.0961366 (rank : 182)	NC score	0.236056 (rank : 99)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	111
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

VGLL4_MOUSE
θ value	0.0961366 (rank : 183)	NC score	0.056926 (rank : 394)
Query Neighborhood Hits	437	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q80V24	Gene names	Vgll4
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 4 (Vgl-4).

LIN7C_HUMAN
θ value	0.125558 (rank : 184)	NC score	0.246690 (rank : 91)
Query Neighborhood Hits	437	Target Neighborhood Hits	198	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.125558 (rank : 185)	NC score	0.246690 (rank : 92)
Query Neighborhood Hits	437	Target Neighborhood Hits	198	Shared Neighborhood Hits	123
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

MAGI1_HUMAN
θ value	0.125558 (rank : 186)	NC score	0.221170 (rank : 123)
Query Neighborhood Hits	437	Target Neighborhood Hits	388	Shared Neighborhood Hits	160
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PAR6B_HUMAN
θ value	0.125558 (rank : 187)	NC score	0.183679 (rank : 166)
Query Neighborhood Hits	437	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

SDCB1_HUMAN
θ value	0.125558 (rank : 188)	NC score	0.154955 (rank : 203)
Query Neighborhood Hits	437	Target Neighborhood Hits	150	Shared Neighborhood Hits	99
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	0.125558 (rank : 189)	NC score	0.157682 (rank : 201)
Query Neighborhood Hits	437	Target Neighborhood Hits	144	Shared Neighborhood Hits	94
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

MPP4_HUMAN
θ value	0.163984 (rank : 190)	NC score	0.159558 (rank : 200)
Query Neighborhood Hits	437	Target Neighborhood Hits	205	Shared Neighborhood Hits	115
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

SNUT3_HUMAN
θ value	0.163984 (rank : 191)	NC score	0.094616 (rank : 278)
Query Neighborhood Hits	437	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WVK2, Q15410	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3 (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (Nucleic acid-binding protein RY-1).

SNUT3_MOUSE
θ value	0.163984 (rank : 192)	NC score	0.090635 (rank : 284)
Query Neighborhood Hits	437	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K194, Q8BRA8, Q9CSV0	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3.

SON_MOUSE
θ value	0.163984 (rank : 193)	NC score	0.073193 (rank : 322)
Query Neighborhood Hits	437	Target Neighborhood Hits	957	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

GIPC3_MOUSE
θ value	0.21417 (rank : 194)	NC score	0.088969 (rank : 289)
Query Neighborhood Hits	437	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

NOS1_HUMAN
θ value	0.21417 (rank : 195)	NC score	0.121756 (rank : 234)
Query Neighborhood Hits	437	Target Neighborhood Hits	218	Shared Neighborhood Hits	109
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PA24F_HUMAN
θ value	0.21417 (rank : 196)	NC score	0.139161 (rank : 220)
Query Neighborhood Hits	437	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PDZK4_MOUSE
θ value	0.21417 (rank : 197)	NC score	0.161316 (rank : 194)
Query Neighborhood Hits	437	Target Neighborhood Hits	165	Shared Neighborhood Hits	102
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SETD8_MOUSE
θ value	0.21417 (rank : 198)	NC score	0.034430 (rank : 486)
Query Neighborhood Hits	437	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SYT14_HUMAN
θ value	0.21417 (rank : 199)	NC score	0.373268 (rank : 58)
Query Neighborhood Hits	437	Target Neighborhood Hits	81	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

ABL1_HUMAN
θ value	0.279714 (rank : 200)	NC score	0.016034 (rank : 549)
Query Neighborhood Hits	437	Target Neighborhood Hits	1220	Shared Neighborhood Hits	58
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

LAD1_MOUSE
θ value	0.279714 (rank : 201)	NC score	0.070491 (rank : 336)
Query Neighborhood Hits	437	Target Neighborhood Hits	391	Shared Neighborhood Hits	51
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MINT_HUMAN
θ value	0.279714 (rank : 202)	NC score	0.070247 (rank : 337)
Query Neighborhood Hits	437	Target Neighborhood Hits	1291	Shared Neighborhood Hits	119
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NOS1_MOUSE
θ value	0.279714 (rank : 203)	NC score	0.103250 (rank : 265)
Query Neighborhood Hits	437	Target Neighborhood Hits	155	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PRRT3_HUMAN
θ value	0.279714 (rank : 204)	NC score	0.060224 (rank : 384)
Query Neighborhood Hits	437	Target Neighborhood Hits	998	Shared Neighborhood Hits	70
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SNTG2_MOUSE
θ value	0.279714 (rank : 205)	NC score	0.216373 (rank : 131)
Query Neighborhood Hits	437	Target Neighborhood Hits	176	Shared Neighborhood Hits	117
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

ZO2_MOUSE
θ value	0.279714 (rank : 206)	NC score	0.184413 (rank : 165)
Query Neighborhood Hits	437	Target Neighborhood Hits	296	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DCAK3_MOUSE
θ value	0.365318 (rank : 207)	NC score	0.017740 (rank : 538)
Query Neighborhood Hits	437	Target Neighborhood Hits	922	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

IBRD1_HUMAN
θ value	0.365318 (rank : 208)	NC score	0.063927 (rank : 365)
Query Neighborhood Hits	437	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

MO4L1_HUMAN
θ value	0.365318 (rank : 209)	NC score	0.032374 (rank : 491)
Query Neighborhood Hits	437	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MO4L1_MOUSE
θ value	0.365318 (rank : 210)	NC score	0.032360 (rank : 492)
Query Neighborhood Hits	437	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

PAR6B_MOUSE
θ value	0.365318 (rank : 211)	NC score	0.182224 (rank : 168)
Query Neighborhood Hits	437	Target Neighborhood Hits	128	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

TP53B_HUMAN
θ value	0.365318 (rank : 212)	NC score	0.052779 (rank : 430)
Query Neighborhood Hits	437	Target Neighborhood Hits	413	Shared Neighborhood Hits	49
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

VGLL4_HUMAN
θ value	0.365318 (rank : 213)	NC score	0.049477 (rank : 453)
Query Neighborhood Hits	437	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q14135, Q7L5V0, Q9BQ78	Gene names	VGLL4, KIAA0121
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 4 (Vgl-4).

ZO2_HUMAN
θ value	0.365318 (rank : 214)	NC score	0.186191 (rank : 161)
Query Neighborhood Hits	437	Target Neighborhood Hits	289	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ANK2_HUMAN
θ value	0.47712 (rank : 215)	NC score	0.034027 (rank : 487)
Query Neighborhood Hits	437	Target Neighborhood Hits	1615	Shared Neighborhood Hits	126
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

COIA1_MOUSE
θ value	0.47712 (rank : 216)	NC score	0.019901 (rank : 531)
Query Neighborhood Hits	437	Target Neighborhood Hits	481	Shared Neighborhood Hits	39
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GIPC3_HUMAN
θ value	0.47712 (rank : 217)	NC score	0.087403 (rank : 293)
Query Neighborhood Hits	437	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GP143_HUMAN
θ value	0.47712 (rank : 218)	NC score	0.072389 (rank : 327)
Query Neighborhood Hits	437	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P51810	Gene names	GPR143, OA1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein).

MYCB2_HUMAN
θ value	0.47712 (rank : 219)	NC score	0.047172 (rank : 457)
Query Neighborhood Hits	437	Target Neighborhood Hits	390	Shared Neighborhood Hits	50
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NALP5_MOUSE
θ value	0.47712 (rank : 220)	NC score	0.028474 (rank : 503)
Query Neighborhood Hits	437	Target Neighborhood Hits	560	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NGEF_MOUSE
θ value	0.47712 (rank : 221)	NC score	0.029236 (rank : 501)
Query Neighborhood Hits	437	Target Neighborhood Hits	228	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

RNF12_MOUSE
θ value	0.47712 (rank : 222)	NC score	0.025293 (rank : 513)
Query Neighborhood Hits	437	Target Neighborhood Hits	159	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

SDCB2_HUMAN
θ value	0.47712 (rank : 223)	NC score	0.119192 (rank : 238)
Query Neighborhood Hits	437	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SYJ2B_HUMAN
θ value	0.47712 (rank : 224)	NC score	0.247405 (rank : 90)
Query Neighborhood Hits	437	Target Neighborhood Hits	162	Shared Neighborhood Hits	113
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

TCAL3_HUMAN
θ value	0.47712 (rank : 225)	NC score	0.054710 (rank : 415)
Query Neighborhood Hits	437	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

APXL_HUMAN
θ value	0.62314 (rank : 226)	NC score	0.127901 (rank : 228)
Query Neighborhood Hits	437	Target Neighborhood Hits	553	Shared Neighborhood Hits	105
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

DVL1_HUMAN
θ value	0.62314 (rank : 227)	NC score	0.144980 (rank : 210)
Query Neighborhood Hits	437	Target Neighborhood Hits	158	Shared Neighborhood Hits	96
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	0.62314 (rank : 228)	NC score	0.140304 (rank : 217)
Query Neighborhood Hits	437	Target Neighborhood Hits	146	Shared Neighborhood Hits	87
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GRIP1_HUMAN
θ value	0.62314 (rank : 229)	NC score	0.226343 (rank : 112)
Query Neighborhood Hits	437	Target Neighborhood Hits	231	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MDC1_HUMAN
θ value	0.62314 (rank : 230)	NC score	0.082069 (rank : 304)
Query Neighborhood Hits	437	Target Neighborhood Hits	1446	Shared Neighborhood Hits	114
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NHERF_HUMAN
θ value	0.62314 (rank : 231)	NC score	0.184599 (rank : 164)
Query Neighborhood Hits	437	Target Neighborhood Hits	190	Shared Neighborhood Hits	102
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PA24F_MOUSE
θ value	0.62314 (rank : 232)	NC score	0.164710 (rank : 192)
Query Neighborhood Hits	437	Target Neighborhood Hits	93	Shared Neighborhood Hits	66
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PTN4_HUMAN
θ value	0.62314 (rank : 233)	NC score	0.052773 (rank : 431)
Query Neighborhood Hits	437	Target Neighborhood Hits	303	Shared Neighborhood Hits	85
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

SDCB2_MOUSE
θ value	0.62314 (rank : 234)	NC score	0.121742 (rank : 235)
Query Neighborhood Hits	437	Target Neighborhood Hits	118	Shared Neighborhood Hits	76
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SFRS4_HUMAN
θ value	0.62314 (rank : 235)	NC score	0.078668 (rank : 312)
Query Neighborhood Hits	437	Target Neighborhood Hits	384	Shared Neighborhood Hits	54
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SFRS5_MOUSE
θ value	0.62314 (rank : 236)	NC score	0.031399 (rank : 494)
Query Neighborhood Hits	437	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	O35326	Gene names	Sfrs5, Hrs
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

SNTB1_HUMAN
θ value	0.62314 (rank : 237)	NC score	0.216263 (rank : 132)
Query Neighborhood Hits	437	Target Neighborhood Hits	157	Shared Neighborhood Hits	102
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

AIM1_HUMAN
θ value	0.813845 (rank : 238)	NC score	0.039777 (rank : 468)
Query Neighborhood Hits	437	Target Neighborhood Hits	247	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

AL2S4_MOUSE
θ value	0.813845 (rank : 239)	NC score	0.043994 (rank : 464)
Query Neighborhood Hits	437	Target Neighborhood Hits	193	Shared Neighborhood Hits	27
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

ANLN_MOUSE
θ value	0.813845 (rank : 240)	NC score	0.030170 (rank : 497)
Query Neighborhood Hits	437	Target Neighborhood Hits	297	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CD2L7_HUMAN
θ value	0.813845 (rank : 241)	NC score	0.019834 (rank : 532)
Query Neighborhood Hits	437	Target Neighborhood Hits	1275	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

DOCK4_HUMAN
θ value	0.813845 (rank : 242)	NC score	0.027823 (rank : 506)
Query Neighborhood Hits	437	Target Neighborhood Hits	237	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MAGI2_HUMAN
θ value	0.813845 (rank : 243)	NC score	0.213499 (rank : 136)
Query Neighborhood Hits	437	Target Neighborhood Hits	373	Shared Neighborhood Hits	145
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

NCOR1_MOUSE
θ value	0.813845 (rank : 244)	NC score	0.045087 (rank : 461)
Query Neighborhood Hits	437	Target Neighborhood Hits	521	Shared Neighborhood Hits	78
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NKTR_HUMAN
θ value	0.813845 (rank : 245)	NC score	0.048746 (rank : 455)
Query Neighborhood Hits	437	Target Neighborhood Hits	658	Shared Neighborhood Hits	84
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RGS12_HUMAN
θ value	0.813845 (rank : 246)	NC score	0.108820 (rank : 252)
Query Neighborhood Hits	437	Target Neighborhood Hits	333	Shared Neighborhood Hits	104
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SFR12_MOUSE
θ value	0.813845 (rank : 247)	NC score	0.086074 (rank : 294)
Query Neighborhood Hits	437	Target Neighborhood Hits	486	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SFRS5_HUMAN
θ value	0.813845 (rank : 248)	NC score	0.029249 (rank : 500)
Query Neighborhood Hits	437	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	Q13243, O14797, Q16662	Gene names	SFRS5, HRS, SRP40
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

SRRM1_MOUSE
θ value	0.813845 (rank : 249)	NC score	0.133340 (rank : 226)
Query Neighborhood Hits	437	Target Neighborhood Hits	966	Shared Neighborhood Hits	125
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TXND2_MOUSE
θ value	0.813845 (rank : 250)	NC score	0.083127 (rank : 302)
Query Neighborhood Hits	437	Target Neighborhood Hits	828	Shared Neighborhood Hits	91
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ACINU_HUMAN
θ value	1.06291 (rank : 251)	NC score	0.073652 (rank : 320)
Query Neighborhood Hits	437	Target Neighborhood Hits	828	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CCNL1_HUMAN
θ value	1.06291 (rank : 252)	NC score	0.038203 (rank : 471)
Query Neighborhood Hits	437	Target Neighborhood Hits	79	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CCNL1_MOUSE
θ value	1.06291 (rank : 253)	NC score	0.039830 (rank : 467)
Query Neighborhood Hits	437	Target Neighborhood Hits	71	Shared Neighborhood Hits	22
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CXCC1_MOUSE
θ value	1.06291 (rank : 254)	NC score	0.035769 (rank : 482)
Query Neighborhood Hits	437	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

DHX8_HUMAN
θ value	1.06291 (rank : 255)	NC score	0.008722 (rank : 580)
Query Neighborhood Hits	437	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

GRIP1_MOUSE
θ value	1.06291 (rank : 256)	NC score	0.222628 (rank : 122)
Query Neighborhood Hits	437	Target Neighborhood Hits	241	Shared Neighborhood Hits	132
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

HNF1B_MOUSE
θ value	1.06291 (rank : 257)	NC score	0.015678 (rank : 551)
Query Neighborhood Hits	437	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

MAP4_MOUSE
θ value	1.06291 (rank : 258)	NC score	0.070899 (rank : 335)
Query Neighborhood Hits	437	Target Neighborhood Hits	409	Shared Neighborhood Hits	48
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAST4_HUMAN
θ value	1.06291 (rank : 259)	NC score	0.050509 (rank : 447)
Query Neighborhood Hits	437	Target Neighborhood Hits	1804	Shared Neighborhood Hits	166
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MBB1A_HUMAN
θ value	1.06291 (rank : 260)	NC score	0.060856 (rank : 382)
Query Neighborhood Hits	437	Target Neighborhood Hits	665	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NHERF_MOUSE
θ value	1.06291 (rank : 261)	NC score	0.183388 (rank : 167)
Query Neighborhood Hits	437	Target Neighborhood Hits	195	Shared Neighborhood Hits	105
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

SVIL_MOUSE
θ value	1.06291 (rank : 262)	NC score	0.044215 (rank : 463)
Query Neighborhood Hits	437	Target Neighborhood Hits	439	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

BOC_HUMAN
θ value	1.38821 (rank : 263)	NC score	0.008421 (rank : 581)
Query Neighborhood Hits	437	Target Neighborhood Hits	543	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

DEK_HUMAN
θ value	1.38821 (rank : 264)	NC score	0.051475 (rank : 439)
Query Neighborhood Hits	437	Target Neighborhood Hits	199	Shared Neighborhood Hits	27
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

DOCK4_MOUSE
θ value	1.38821 (rank : 265)	NC score	0.026493 (rank : 509)
Query Neighborhood Hits	437	Target Neighborhood Hits	210	Shared Neighborhood Hits	28
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DVL1L_HUMAN
θ value	1.38821 (rank : 266)	NC score	0.135093 (rank : 222)
Query Neighborhood Hits	437	Target Neighborhood Hits	146	Shared Neighborhood Hits	88
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

ETV3_HUMAN
θ value	1.38821 (rank : 267)	NC score	0.015223 (rank : 552)
Query Neighborhood Hits	437	Target Neighborhood Hits	312	Shared Neighborhood Hits	29
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FAK1_HUMAN
θ value	1.38821 (rank : 268)	NC score	0.007733 (rank : 587)
Query Neighborhood Hits	437	Target Neighborhood Hits	850	Shared Neighborhood Hits	27
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	1.38821 (rank : 269)	NC score	0.007164 (rank : 589)
Query Neighborhood Hits	437	Target Neighborhood Hits	850	Shared Neighborhood Hits	25
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

NACAM_MOUSE
θ value	1.38821 (rank : 270)	NC score	0.068206 (rank : 344)
Query Neighborhood Hits	437	Target Neighborhood Hits	1866	Shared Neighborhood Hits	119
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NEK4_MOUSE
θ value	1.38821 (rank : 271)	NC score	0.013232 (rank : 559)
Query Neighborhood Hits	437	Target Neighborhood Hits	899	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

OSB11_MOUSE
θ value	1.38821 (rank : 272)	NC score	0.011484 (rank : 567)
Query Neighborhood Hits	437	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

PA24D_HUMAN
θ value	1.38821 (rank : 273)	NC score	0.237655 (rank : 97)
Query Neighborhood Hits	437	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PA24E_HUMAN
θ value	1.38821 (rank : 274)	NC score	0.184886 (rank : 163)
Query Neighborhood Hits	437	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

RAI1_HUMAN
θ value	1.38821 (rank : 275)	NC score	0.038866 (rank : 470)
Query Neighborhood Hits	437	Target Neighborhood Hits	360	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SMUF1_HUMAN
θ value	1.38821 (rank : 276)	NC score	0.109525 (rank : 251)
Query Neighborhood Hits	437	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	1.38821 (rank : 277)	NC score	0.108652 (rank : 253)
Query Neighborhood Hits	437	Target Neighborhood Hits	142	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SRBS1_MOUSE
θ value	1.38821 (rank : 278)	NC score	0.032383 (rank : 490)
Query Neighborhood Hits	437	Target Neighborhood Hits	409	Shared Neighborhood Hits	37
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

TRA2B_HUMAN
θ value	1.38821 (rank : 279)	NC score	0.016649 (rank : 544)
Query Neighborhood Hits	437	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	P62995, O15449, Q15815, Q64283	Gene names	SFRS10, TRA2B
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich-splicing factor 10 (Transformer-2-beta) (HTRA2- beta) (Transformer 2 protein homolog).

TRA2B_MOUSE
θ value	1.38821 (rank : 280)	NC score	0.016649 (rank : 545)
Query Neighborhood Hits	437	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	P62996, O15449, Q15815, Q64283	Gene names	Sfrs10, Silg41, Tra2b
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich-splicing factor 10 (Transformer-2-beta) (HTRA2- beta) (Transformer 2 protein homolog) (Silica-induced gene 41 protein) (SIG-41).

TTF2_MOUSE
θ value	1.38821 (rank : 281)	NC score	0.035407 (rank : 483)
Query Neighborhood Hits	437	Target Neighborhood Hits	364	Shared Neighborhood Hits	61
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ZAR1_MOUSE
θ value	1.38821 (rank : 282)	NC score	0.049921 (rank : 452)
Query Neighborhood Hits	437	Target Neighborhood Hits	254	Shared Neighborhood Hits	22
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ANR11_HUMAN
θ value	1.81305 (rank : 283)	NC score	0.033154 (rank : 488)
Query Neighborhood Hits	437	Target Neighborhood Hits	1289	Shared Neighborhood Hits	105
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CROP_MOUSE
θ value	1.81305 (rank : 284)	NC score	0.043062 (rank : 466)
Query Neighborhood Hits	437	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CS029_MOUSE
θ value	1.81305 (rank : 285)	NC score	0.026185 (rank : 510)
Query Neighborhood Hits	437	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

DVL2_MOUSE
θ value	1.81305 (rank : 286)	NC score	0.141429 (rank : 214)
Query Neighborhood Hits	437	Target Neighborhood Hits	233	Shared Neighborhood Hits	99
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

GIPC2_HUMAN
θ value	1.81305 (rank : 287)	NC score	0.110732 (rank : 248)
Query Neighborhood Hits	437	Target Neighborhood Hits	93	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

GIPC2_MOUSE
θ value	1.81305 (rank : 288)	NC score	0.093926 (rank : 279)
Query Neighborhood Hits	437	Target Neighborhood Hits	71	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

JHD2C_MOUSE
θ value	1.81305 (rank : 289)	NC score	0.021750 (rank : 522)
Query Neighborhood Hits	437	Target Neighborhood Hits	297	Shared Neighborhood Hits	42
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

K0528_HUMAN
θ value	1.81305 (rank : 290)	NC score	0.280026 (rank : 73)
Query Neighborhood Hits	437	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	1.81305 (rank : 291)	NC score	0.281529 (rank : 72)
Query Neighborhood Hits	437	Target Neighborhood Hits	102	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

MAGI2_MOUSE
θ value	1.81305 (rank : 292)	NC score	0.212715 (rank : 138)
Query Neighborhood Hits	437	Target Neighborhood Hits	370	Shared Neighborhood Hits	144
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAST1_HUMAN
θ value	1.81305 (rank : 293)	NC score	0.038999 (rank : 469)
Query Neighborhood Hits	437	Target Neighborhood Hits	1146	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_MOUSE
θ value	1.81305 (rank : 294)	NC score	0.036730 (rank : 476)
Query Neighborhood Hits	437	Target Neighborhood Hits	1110	Shared Neighborhood Hits	111
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MO4L2_HUMAN
θ value	1.81305 (rank : 295)	NC score	0.036281 (rank : 479)
Query Neighborhood Hits	437	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

PA24E_MOUSE
θ value	1.81305 (rank : 296)	NC score	0.201025 (rank : 143)
Query Neighborhood Hits	437	Target Neighborhood Hits	95	Shared Neighborhood Hits	76
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SFR17_HUMAN
θ value	1.81305 (rank : 297)	NC score	0.064796 (rank : 362)
Query Neighborhood Hits	437	Target Neighborhood Hits	325	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SMUF2_HUMAN
θ value	1.81305 (rank : 298)	NC score	0.107696 (rank : 255)
Query Neighborhood Hits	437	Target Neighborhood Hits	142	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SPEG_MOUSE
θ value	1.81305 (rank : 299)	NC score	0.029657 (rank : 498)
Query Neighborhood Hits	437	Target Neighborhood Hits	1959	Shared Neighborhood Hits	113
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TCAL5_MOUSE
θ value	1.81305 (rank : 300)	NC score	0.066222 (rank : 354)
Query Neighborhood Hits	437	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CCT4, Q497R6	Gene names	Tceal5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCAL6_HUMAN
θ value	1.81305 (rank : 301)	NC score	0.055763 (rank : 398)
Query Neighborhood Hits	437	Target Neighborhood Hits	122	Shared Neighborhood Hits	23
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

3BP1_MOUSE
θ value	2.36792 (rank : 302)	NC score	0.026783 (rank : 508)
Query Neighborhood Hits	437	Target Neighborhood Hits	238	Shared Neighborhood Hits	34
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ATX2L_HUMAN
θ value	2.36792 (rank : 303)	NC score	0.043579 (rank : 465)
Query Neighborhood Hits	437	Target Neighborhood Hits	443	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CABIN_HUMAN
θ value	2.36792 (rank : 304)	NC score	0.055692 (rank : 399)
Query Neighborhood Hits	437	Target Neighborhood Hits	490	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

DVL2_HUMAN
θ value	2.36792 (rank : 305)	NC score	0.139776 (rank : 218)
Query Neighborhood Hits	437	Target Neighborhood Hits	223	Shared Neighborhood Hits	100
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	2.36792 (rank : 306)	NC score	0.144474 (rank : 211)
Query Neighborhood Hits	437	Target Neighborhood Hits	194	Shared Neighborhood Hits	91
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	2.36792 (rank : 307)	NC score	0.146404 (rank : 209)
Query Neighborhood Hits	437	Target Neighborhood Hits	198	Shared Neighborhood Hits	96
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

MAP1B_HUMAN
θ value	2.36792 (rank : 308)	NC score	0.064735 (rank : 363)
Query Neighborhood Hits	437	Target Neighborhood Hits	903	Shared Neighborhood Hits	89
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP4_HUMAN
θ value	2.36792 (rank : 309)	NC score	0.061128 (rank : 378)
Query Neighborhood Hits	437	Target Neighborhood Hits	428	Shared Neighborhood Hits	47
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MYRIP_MOUSE
θ value	2.36792 (rank : 310)	NC score	0.146498 (rank : 208)
Query Neighborhood Hits	437	Target Neighborhood Hits	207	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PDZD3_MOUSE
θ value	2.36792 (rank : 311)	NC score	0.155656 (rank : 202)
Query Neighborhood Hits	437	Target Neighborhood Hits	171	Shared Neighborhood Hits	95
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PHF22_HUMAN
θ value	2.36792 (rank : 312)	NC score	0.022579 (rank : 517)
Query Neighborhood Hits	437	Target Neighborhood Hits	121	Shared Neighborhood Hits	14
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PRP4B_MOUSE
θ value	2.36792 (rank : 313)	NC score	0.028747 (rank : 502)
Query Neighborhood Hits	437	Target Neighborhood Hits	1040	Shared Neighborhood Hits	70
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SFR11_HUMAN
θ value	2.36792 (rank : 314)	NC score	0.108547 (rank : 254)
Query Neighborhood Hits	437	Target Neighborhood Hits	246	Shared Neighborhood Hits	45
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFRS4_MOUSE
θ value	2.36792 (rank : 315)	NC score	0.072529 (rank : 326)
Query Neighborhood Hits	437	Target Neighborhood Hits	406	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SNTG1_MOUSE
θ value	2.36792 (rank : 316)	NC score	0.190513 (rank : 156)
Query Neighborhood Hits	437	Target Neighborhood Hits	179	Shared Neighborhood Hits	119
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SPAG1_MOUSE
θ value	2.36792 (rank : 317)	NC score	0.007851 (rank : 584)
Query Neighborhood Hits	437	Target Neighborhood Hits	218	Shared Neighborhood Hits	12
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

DDX46_HUMAN
θ value	3.0926 (rank : 318)	NC score	0.011038 (rank : 570)
Query Neighborhood Hits	437	Target Neighborhood Hits	357	Shared Neighborhood Hits	36
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	3.0926 (rank : 319)	NC score	0.010442 (rank : 575)
Query Neighborhood Hits	437	Target Neighborhood Hits	358	Shared Neighborhood Hits	38
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

HDAC9_HUMAN
θ value	3.0926 (rank : 320)	NC score	0.008954 (rank : 579)
Query Neighborhood Hits	437	Target Neighborhood Hits	201	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

MPP4_MOUSE
θ value	3.0926 (rank : 321)	NC score	0.127845 (rank : 229)
Query Neighborhood Hits	437	Target Neighborhood Hits	188	Shared Neighborhood Hits	101
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MYCB2_MOUSE
θ value	3.0926 (rank : 322)	NC score	0.044446 (rank : 462)
Query Neighborhood Hits	437	Target Neighborhood Hits	307	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

QSCN6_HUMAN
θ value	3.0926 (rank : 323)	NC score	0.010810 (rank : 572)
Query Neighborhood Hits	437	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

RM23_HUMAN
θ value	3.0926 (rank : 324)	NC score	0.019465 (rank : 535)
Query Neighborhood Hits	437	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q16540, Q96Q71	Gene names	MRPL23, L23MRP, RPL23L
Domain Architecture	No domain graphic available
Description	Mitochondrial 39S ribosomal protein L23 (L23mt) (MRP-L23) (L23 mitochondrial-related protein) (Ribosomal protein L23-like).

RNF12_HUMAN
θ value	3.0926 (rank : 325)	NC score	0.024189 (rank : 516)
Query Neighborhood Hits	437	Target Neighborhood Hits	173	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

SFRS6_HUMAN
θ value	3.0926 (rank : 326)	NC score	0.036727 (rank : 477)
Query Neighborhood Hits	437	Target Neighborhood Hits	247	Shared Neighborhood Hits	33
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

SFRS8_HUMAN
θ value	3.0926 (rank : 327)	NC score	0.060895 (rank : 381)
Query Neighborhood Hits	437	Target Neighborhood Hits	166	Shared Neighborhood Hits	35
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SNTG1_HUMAN
θ value	3.0926 (rank : 328)	NC score	0.188286 (rank : 160)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SYNP2_HUMAN
θ value	3.0926 (rank : 329)	NC score	0.073621 (rank : 321)
Query Neighborhood Hits	437	Target Neighborhood Hits	323	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYNP2_MOUSE
θ value	3.0926 (rank : 330)	NC score	0.104976 (rank : 260)
Query Neighborhood Hits	437	Target Neighborhood Hits	252	Shared Neighborhood Hits	96
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

TCAL3_MOUSE
θ value	3.0926 (rank : 331)	NC score	0.072212 (rank : 329)
Query Neighborhood Hits	437	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

ZMY11_HUMAN
θ value	3.0926 (rank : 332)	NC score	0.014889 (rank : 553)
Query Neighborhood Hits	437	Target Neighborhood Hits	201	Shared Neighborhood Hits	5
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	3.0926 (rank : 333)	NC score	0.014767 (rank : 555)
Query Neighborhood Hits	437	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

APBA1_HUMAN
θ value	4.03905 (rank : 334)	NC score	0.151768 (rank : 205)
Query Neighborhood Hits	437	Target Neighborhood Hits	325	Shared Neighborhood Hits	125
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

BOC_MOUSE
θ value	4.03905 (rank : 335)	NC score	0.008034 (rank : 583)
Query Neighborhood Hits	437	Target Neighborhood Hits	433	Shared Neighborhood Hits	13
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CDKL5_HUMAN
θ value	4.03905 (rank : 336)	NC score	0.017607 (rank : 539)
Query Neighborhood Hits	437	Target Neighborhood Hits	967	Shared Neighborhood Hits	56
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CJ012_HUMAN
θ value	4.03905 (rank : 337)	NC score	0.064950 (rank : 359)
Query Neighborhood Hits	437	Target Neighborhood Hits	467	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

DSPP_MOUSE
θ value	4.03905 (rank : 338)	NC score	0.061685 (rank : 373)
Query Neighborhood Hits	437	Target Neighborhood Hits	491	Shared Neighborhood Hits	57
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

EEA1_HUMAN
θ value	4.03905 (rank : 339)	NC score	0.014382 (rank : 557)
Query Neighborhood Hits	437	Target Neighborhood Hits	1796	Shared Neighborhood Hits	68
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

HXC10_MOUSE
θ value	4.03905 (rank : 340)	NC score	0.001907 (rank : 604)
Query Neighborhood Hits	437	Target Neighborhood Hits	417	Shared Neighborhood Hits	23
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

NRAP_MOUSE
θ value	4.03905 (rank : 341)	NC score	0.006178 (rank : 593)
Query Neighborhood Hits	437	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

RBBP6_MOUSE
θ value	4.03905 (rank : 342)	NC score	0.072122 (rank : 331)
Query Neighborhood Hits	437	Target Neighborhood Hits	1014	Shared Neighborhood Hits	101
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RPTN_MOUSE
θ value	4.03905 (rank : 343)	NC score	0.036276 (rank : 481)
Query Neighborhood Hits	437	Target Neighborhood Hits	650	Shared Neighborhood Hits	72
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RTN4_HUMAN
θ value	4.03905 (rank : 344)	NC score	0.030487 (rank : 495)
Query Neighborhood Hits	437	Target Neighborhood Hits	357	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SFRS2_HUMAN
θ value	4.03905 (rank : 345)	NC score	0.022057 (rank : 520)
Query Neighborhood Hits	437	Target Neighborhood Hits	222	Shared Neighborhood Hits	29
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
θ value	4.03905 (rank : 346)	NC score	0.022057 (rank : 521)
Query Neighborhood Hits	437	Target Neighborhood Hits	222	Shared Neighborhood Hits	29
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

SFRS7_HUMAN
θ value	4.03905 (rank : 347)	NC score	0.027587 (rank : 507)
Query Neighborhood Hits	437	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q16629	Gene names	SFRS7
Domain Architecture
Description	Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

SYAM_MOUSE
θ value	4.03905 (rank : 348)	NC score	0.009576 (rank : 578)
Query Neighborhood Hits	437	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q14CH7, Q68FH3, Q69ZM9	Gene names	Aarsl, Aars2, Kiaa1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

TAU_MOUSE
θ value	4.03905 (rank : 349)	NC score	0.049243 (rank : 454)
Query Neighborhood Hits	437	Target Neighborhood Hits	502	Shared Neighborhood Hits	46
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ZN638_MOUSE
θ value	4.03905 (rank : 350)	NC score	0.020740 (rank : 527)
Query Neighborhood Hits	437	Target Neighborhood Hits	318	Shared Neighborhood Hits	34
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

AHTF1_MOUSE
θ value	5.27518 (rank : 351)	NC score	0.036280 (rank : 480)
Query Neighborhood Hits	437	Target Neighborhood Hits	176	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

AKAP2_HUMAN
θ value	5.27518 (rank : 352)	NC score	0.019601 (rank : 533)
Query Neighborhood Hits	437	Target Neighborhood Hits	507	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

APBA2_HUMAN
θ value	5.27518 (rank : 353)	NC score	0.137963 (rank : 221)
Query Neighborhood Hits	437	Target Neighborhood Hits	220	Shared Neighborhood Hits	111
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

CHD1_HUMAN
θ value	5.27518 (rank : 354)	NC score	0.019264 (rank : 536)
Query Neighborhood Hits	437	Target Neighborhood Hits	337	Shared Neighborhood Hits	39
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CNKR2_HUMAN
θ value	5.27518 (rank : 355)	NC score	0.046719 (rank : 459)
Query Neighborhood Hits	437	Target Neighborhood Hits	197	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	5.27518 (rank : 356)	NC score	0.046831 (rank : 458)
Query Neighborhood Hits	437	Target Neighborhood Hits	197	Shared Neighborhood Hits	52
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CROP_HUMAN
θ value	5.27518 (rank : 357)	NC score	0.045132 (rank : 460)
Query Neighborhood Hits	437	Target Neighborhood Hits	402	Shared Neighborhood Hits	41
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CSPG2_HUMAN
θ value	5.27518 (rank : 358)	NC score	0.002389 (rank : 603)
Query Neighborhood Hits	437	Target Neighborhood Hits	681	Shared Neighborhood Hits	30
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

DSPP_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.064922 (rank : 360)
Query Neighborhood Hits	437	Target Neighborhood Hits	645	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

EEA1_MOUSE
θ value	5.27518 (rank : 360)	NC score	0.010515 (rank : 574)
Query Neighborhood Hits	437	Target Neighborhood Hits	1637	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FOXB2_MOUSE
θ value	5.27518 (rank : 361)	NC score	0.005358 (rank : 595)
Query Neighborhood Hits	437	Target Neighborhood Hits	139	Shared Neighborhood Hits	14
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

GCP6_HUMAN
θ value	5.27518 (rank : 362)	NC score	0.011492 (rank : 566)
Query Neighborhood Hits	437	Target Neighborhood Hits	295	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

HDAC6_HUMAN
θ value	5.27518 (rank : 363)	NC score	0.008390 (rank : 582)
Query Neighborhood Hits	437	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

MAST1_MOUSE
θ value	5.27518 (rank : 364)	NC score	0.037796 (rank : 472)
Query Neighborhood Hits	437	Target Neighborhood Hits	1123	Shared Neighborhood Hits	111
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.037118 (rank : 474)
Query Neighborhood Hits	437	Target Neighborhood Hits	1189	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

RBBP6_HUMAN
θ value	5.27518 (rank : 366)	NC score	0.071576 (rank : 334)
Query Neighborhood Hits	437	Target Neighborhood Hits	1135	Shared Neighborhood Hits	120
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RYR2_HUMAN
θ value	5.27518 (rank : 367)	NC score	0.006841 (rank : 590)
Query Neighborhood Hits	437	Target Neighborhood Hits	175	Shared Neighborhood Hits	10
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

SYGP1_HUMAN
θ value	5.27518 (rank : 368)	NC score	0.024275 (rank : 515)
Query Neighborhood Hits	437	Target Neighborhood Hits	589	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

TDRD6_MOUSE
θ value	5.27518 (rank : 369)	NC score	0.018451 (rank : 537)
Query Neighborhood Hits	437	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

TRPC4_HUMAN
θ value	5.27518 (rank : 370)	NC score	0.003713 (rank : 599)
Query Neighborhood Hits	437	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

ZEP2_HUMAN
θ value	5.27518 (rank : 371)	NC score	0.005655 (rank : 594)
Query Neighborhood Hits	437	Target Neighborhood Hits	937	Shared Neighborhood Hits	41
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZRAB2_HUMAN
θ value	5.27518 (rank : 372)	NC score	0.057487 (rank : 391)
Query Neighborhood Hits	437	Target Neighborhood Hits	120	Shared Neighborhood Hits	27
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

CXCC1_HUMAN
θ value	6.88961 (rank : 373)	NC score	0.026028 (rank : 511)
Query Neighborhood Hits	437	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

DEDD2_MOUSE
θ value	6.88961 (rank : 374)	NC score	0.010254 (rank : 576)
Query Neighborhood Hits	437	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q8QZV0, Q569Y9, Q8JZV1	Gene names	Dedd2, Flame3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

DYSF_HUMAN
θ value	6.88961 (rank : 375)	NC score	0.226952 (rank : 110)
Query Neighborhood Hits	437	Target Neighborhood Hits	170	Shared Neighborhood Hits	95
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_MOUSE
θ value	6.88961 (rank : 376)	NC score	0.215630 (rank : 133)
Query Neighborhood Hits	437	Target Neighborhood Hits	162	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

FYV1_MOUSE
θ value	6.88961 (rank : 377)	NC score	0.007752 (rank : 586)
Query Neighborhood Hits	437	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

GP142_HUMAN
θ value	6.88961 (rank : 378)	NC score	0.000085 (rank : 609)
Query Neighborhood Hits	437	Target Neighborhood Hits	417	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z601, Q86SL3	Gene names	GPR142, PGR2
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 142 (G-protein coupled receptor PGR2).

HPS4_HUMAN
θ value	6.88961 (rank : 379)	NC score	0.010564 (rank : 573)
Query Neighborhood Hits	437	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQG7, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38	Gene names	HPS4, KIAA1667
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog).

I12R2_MOUSE
θ value	6.88961 (rank : 380)	NC score	0.006588 (rank : 592)
Query Neighborhood Hits	437	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

JHD2C_HUMAN
θ value	6.88961 (rank : 381)	NC score	0.021673 (rank : 523)
Query Neighborhood Hits	437	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

LSR_HUMAN
θ value	6.88961 (rank : 382)	NC score	0.010977 (rank : 571)
Query Neighborhood Hits	437	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

MKRN3_HUMAN
θ value	6.88961 (rank : 383)	NC score	0.014835 (rank : 554)
Query Neighborhood Hits	437	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MRP9_MOUSE
θ value	6.88961 (rank : 384)	NC score	-0.000298 (rank : 610)
Query Neighborhood Hits	437	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MYRIP_HUMAN
θ value	6.88961 (rank : 385)	NC score	0.124869 (rank : 232)
Query Neighborhood Hits	437	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NOLC1_HUMAN
θ value	6.88961 (rank : 386)	NC score	0.109605 (rank : 250)
Query Neighborhood Hits	437	Target Neighborhood Hits	452	Shared Neighborhood Hits	74
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PCNT_HUMAN
θ value	6.88961 (rank : 387)	NC score	0.017447 (rank : 541)
Query Neighborhood Hits	437	Target Neighborhood Hits	1551	Shared Neighborhood Hits	62
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

R4RL1_MOUSE
θ value	6.88961 (rank : 388)	NC score	-0.000377 (rank : 611)
Query Neighborhood Hits	437	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0S5	Gene names	Rtn4rl1, Ngrl2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

RBM16_HUMAN
θ value	6.88961 (rank : 389)	NC score	0.020437 (rank : 529)
Query Neighborhood Hits	437	Target Neighborhood Hits	300	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RBM6_HUMAN
θ value	6.88961 (rank : 390)	NC score	0.022555 (rank : 518)
Query Neighborhood Hits	437	Target Neighborhood Hits	221	Shared Neighborhood Hits	31
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

RP1L1_HUMAN
θ value	6.88961 (rank : 391)	NC score	0.065030 (rank : 358)
Query Neighborhood Hits	437	Target Neighborhood Hits	1072	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SUFU_HUMAN
θ value	6.88961 (rank : 392)	NC score	0.012735 (rank : 560)
Query Neighborhood Hits	437	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMX1, Q7LCP7, Q9NT90, Q9NZ07, Q9UHK2, Q9UHM8, Q9UMY0	Gene names	SUFU
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog (SUFUH).

UBP31_HUMAN
θ value	6.88961 (rank : 393)	NC score	0.031751 (rank : 493)
Query Neighborhood Hits	437	Target Neighborhood Hits	293	Shared Neighborhood Hits	51
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

XE7_HUMAN
θ value	6.88961 (rank : 394)	NC score	0.021366 (rank : 525)
Query Neighborhood Hits	437	Target Neighborhood Hits	738	Shared Neighborhood Hits	47
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ZBT16_HUMAN
θ value	6.88961 (rank : 395)	NC score	-0.009886 (rank : 614)
Query Neighborhood Hits	437	Target Neighborhood Hits	1010	Shared Neighborhood Hits	18
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZEP2_MOUSE
θ value	6.88961 (rank : 396)	NC score	0.002493 (rank : 602)
Query Neighborhood Hits	437	Target Neighborhood Hits	964	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

AB1IP_MOUSE
θ value	8.99809 (rank : 397)	NC score	0.022432 (rank : 519)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ABCF2_MOUSE
θ value	8.99809 (rank : 398)	NC score	0.001654 (rank : 606)
Query Neighborhood Hits	437	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

ADA12_MOUSE
θ value	8.99809 (rank : 399)	NC score	0.004743 (rank : 597)
Query Neighborhood Hits	437	Target Neighborhood Hits	474	Shared Neighborhood Hits	24
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BNIP3_MOUSE
θ value	8.99809 (rank : 400)	NC score	0.007488 (rank : 588)
Query Neighborhood Hits	437	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	O55003, Q544Y4	Gene names	Bnip3, Nip3
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.

CAC1E_MOUSE
θ value	8.99809 (rank : 401)	NC score	0.003195 (rank : 600)
Query Neighborhood Hits	437	Target Neighborhood Hits	167	Shared Neighborhood Hits	22
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CACB2_HUMAN
θ value	8.99809 (rank : 402)	NC score	0.021568 (rank : 524)
Query Neighborhood Hits	437	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CD2_HUMAN
θ value	8.99809 (rank : 403)	NC score	0.016862 (rank : 543)
Query Neighborhood Hits	437	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CI039_HUMAN
θ value	8.99809 (rank : 404)	NC score	0.016546 (rank : 546)
Query Neighborhood Hits	437	Target Neighborhood Hits	1171	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CTDP1_MOUSE
θ value	8.99809 (rank : 405)	NC score	0.014745 (rank : 556)
Query Neighborhood Hits	437	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

EM55_MOUSE
θ value	8.99809 (rank : 406)	NC score	0.113985 (rank : 242)
Query Neighborhood Hits	437	Target Neighborhood Hits	221	Shared Neighborhood Hits	106
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

FA13C_MOUSE
θ value	8.99809 (rank : 407)	NC score	0.015681 (rank : 550)
Query Neighborhood Hits	437	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GP179_HUMAN
θ value	8.99809 (rank : 408)	NC score	0.020671 (rank : 528)
Query Neighborhood Hits	437	Target Neighborhood Hits	372	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

K0494_MOUSE
θ value	8.99809 (rank : 409)	NC score	0.007835 (rank : 585)
Query Neighborhood Hits	437	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

LYST_HUMAN
θ value	8.99809 (rank : 410)	NC score	0.002620 (rank : 601)
Query Neighborhood Hits	437	Target Neighborhood Hits	324	Shared Neighborhood Hits	16
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

M3K3_HUMAN
θ value	8.99809 (rank : 411)	NC score	0.011936 (rank : 563)
Query Neighborhood Hits	437	Target Neighborhood Hits	885	Shared Neighborhood Hits	34
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MDC1_MOUSE
θ value	8.99809 (rank : 412)	NC score	0.060986 (rank : 379)
Query Neighborhood Hits	437	Target Neighborhood Hits	998	Shared Neighborhood Hits	87
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MK07_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.011408 (rank : 568)
Query Neighborhood Hits	437	Target Neighborhood Hits	1087	Shared Neighborhood Hits	53
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MUC1_HUMAN
θ value	8.99809 (rank : 414)	NC score	0.048347 (rank : 456)
Query Neighborhood Hits	437	Target Neighborhood Hits	975	Shared Neighborhood Hits	67
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NADAP_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.019511 (rank : 534)
Query Neighborhood Hits	437	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

PAX3_HUMAN
θ value	8.99809 (rank : 416)	NC score	0.000173 (rank : 608)
Query Neighborhood Hits	437	Target Neighborhood Hits	513	Shared Neighborhood Hits	19
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

PAX3_MOUSE
θ value	8.99809 (rank : 417)	NC score	-0.000684 (rank : 612)
Query Neighborhood Hits	437	Target Neighborhood Hits	478	Shared Neighborhood Hits	18
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

PDZD1_MOUSE
θ value	8.99809 (rank : 418)	NC score	0.180329 (rank : 171)
Query Neighborhood Hits	437	Target Neighborhood Hits	191	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PHLB2_HUMAN
θ value	8.99809 (rank : 419)	NC score	0.010253 (rank : 577)
Query Neighborhood Hits	437	Target Neighborhood Hits	964	Shared Neighborhood Hits	43
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PO3F3_HUMAN
θ value	8.99809 (rank : 420)	NC score	0.001343 (rank : 607)
Query Neighborhood Hits	437	Target Neighborhood Hits	311	Shared Neighborhood Hits	9
SwissProt Accessions	P20264, P78379	Gene names	POU3F3, BRN1, OTF8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

PO3F3_MOUSE
θ value	8.99809 (rank : 421)	NC score	0.001744 (rank : 605)
Query Neighborhood Hits	437	Target Neighborhood Hits	308	Shared Neighborhood Hits	9
SwissProt Accessions	P31361	Gene names	Pou3f3, Brn-1, Brn1, Otf8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

RIF1_MOUSE
θ value	8.99809 (rank : 422)	NC score	0.020966 (rank : 526)
Query Neighborhood Hits	437	Target Neighborhood Hits	315	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

RPB9_HUMAN
θ value	8.99809 (rank : 423)	NC score	0.012441 (rank : 561)
Query Neighborhood Hits	437	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P36954, Q6NW05	Gene names	POLR2I
Domain Architecture
Description	DNA-directed RNA polymerase II subunit I (EC 2.7.7.6) (DNA-directed RNA polymerase II 14.5 kDa polypeptide) (RPB9) (RPB14.5).

RPB9_MOUSE
θ value	8.99809 (rank : 424)	NC score	0.012441 (rank : 562)
Query Neighborhood Hits	437	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P60898	Gene names	Polr2i
Domain Architecture
Description	DNA-directed RNA polymerase II subunit I (EC 2.7.7.6) (DNA-directed RNA polymerase II 14.5 kDa polypeptide) (RPB9) (RPB14.5).

SFR12_HUMAN
θ value	8.99809 (rank : 425)	NC score	0.073844 (rank : 319)
Query Neighborhood Hits	437	Target Neighborhood Hits	553	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SHAN1_HUMAN
θ value	8.99809 (rank : 426)	NC score	0.066493 (rank : 353)
Query Neighborhood Hits	437	Target Neighborhood Hits	1041	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SSFA2_HUMAN
θ value	8.99809 (rank : 427)	NC score	0.011513 (rank : 565)
Query Neighborhood Hits	437	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	P28290, Q96E36	Gene names	SSFA2, CS1
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2 (Cleavage signal-1 protein) (CS-1).

SUFU_MOUSE
θ value	8.99809 (rank : 428)	NC score	0.011641 (rank : 564)
Query Neighborhood Hits	437	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P7, Q8C8B4, Q99JG0, Q9D521, Q9JLU1	Gene names	Sufu
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog.

SUHW2_HUMAN
θ value	8.99809 (rank : 429)	NC score	-0.008386 (rank : 613)
Query Neighborhood Hits	437	Target Neighborhood Hits	683	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YH2	Gene names	SUHW2, ZNF632
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 2 (5'OY11.1) (Zinc finger protein 632).

SYFA_HUMAN
θ value	8.99809 (rank : 430)	NC score	0.011373 (rank : 569)
Query Neighborhood Hits	437	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y285, Q9NSD8, Q9Y4W8	Gene names	FARSLA, FARS, FARSA, FARSL
Domain Architecture
Description	Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase alpha chain) (PheRS) (CML33).

TACC2_MOUSE
θ value	8.99809 (rank : 431)	NC score	0.025794 (rank : 512)
Query Neighborhood Hits	437	Target Neighborhood Hits	774	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TPR_HUMAN
θ value	8.99809 (rank : 432)	NC score	0.013809 (rank : 558)
Query Neighborhood Hits	437	Target Neighborhood Hits	1921	Shared Neighborhood Hits	87
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRPC2_MOUSE
θ value	8.99809 (rank : 433)	NC score	0.004426 (rank : 598)
Query Neighborhood Hits	437	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TTBK1_HUMAN
θ value	8.99809 (rank : 434)	NC score	0.017552 (rank : 540)
Query Neighborhood Hits	437	Target Neighborhood Hits	1058	Shared Neighborhood Hits	77
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TXLNB_HUMAN
θ value	8.99809 (rank : 435)	NC score	0.016253 (rank : 547)
Query Neighborhood Hits	437	Target Neighborhood Hits	912	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

XKR7_MOUSE
θ value	8.99809 (rank : 436)	NC score	0.006841 (rank : 591)
Query Neighborhood Hits	437	Target Neighborhood Hits	146	Shared Neighborhood Hits	14
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

ZNFX1_MOUSE
θ value	8.99809 (rank : 437)	NC score	0.004825 (rank : 596)
Query Neighborhood Hits	437	Target Neighborhood Hits	407	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ACINU_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.053794 (rank : 423)
Query Neighborhood Hits	437	Target Neighborhood Hits	712	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFAD_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.167743 (rank : 187)
Query Neighborhood Hits	437	Target Neighborhood Hits	689	Shared Neighborhood Hits	142
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AFF1_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.062015 (rank : 371)
Query Neighborhood Hits	437	Target Neighborhood Hits	506	Shared Neighborhood Hits	74
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF4_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.054797 (rank : 413)
Query Neighborhood Hits	437	Target Neighborhood Hits	611	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.050243 (rank : 449)
Query Neighborhood Hits	437	Target Neighborhood Hits	581	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

APBA3_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.126883 (rank : 230)
Query Neighborhood Hits	437	Target Neighborhood Hits	201	Shared Neighborhood Hits	109
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.117673 (rank : 239)
Query Neighborhood Hits	437	Target Neighborhood Hits	174	Shared Neighborhood Hits	102
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHGB_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.096962 (rank : 276)
Query Neighborhood Hits	437	Target Neighborhood Hits	375	Shared Neighborhood Hits	119
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.088108 (rank : 291)
Query Neighborhood Hits	437	Target Neighborhood Hits	351	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.088321 (rank : 290)
Query Neighborhood Hits	437	Target Neighborhood Hits	344	Shared Neighborhood Hits	110
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BAG3_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.055238 (rank : 406)
Query Neighborhood Hits	437	Target Neighborhood Hits	314	Shared Neighborhood Hits	50
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.051080 (rank : 443)
Query Neighborhood Hits	437	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BAIP3_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.301360 (rank : 66)
Query Neighborhood Hits	437	Target Neighborhood Hits	108	Shared Neighborhood Hits	75
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.293240 (rank : 69)
Query Neighborhood Hits	437	Target Neighborhood Hits	112	Shared Neighborhood Hits	78
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BASP_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.107537 (rank : 256)
Query Neighborhood Hits	437	Target Neighborhood Hits	321	Shared Neighborhood Hits	60
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.084147 (rank : 299)
Query Neighborhood Hits	437	Target Neighborhood Hits	260	Shared Neighborhood Hits	48
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.055418 (rank : 403)
Query Neighborhood Hits	437	Target Neighborhood Hits	931	Shared Neighborhood Hits	94
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.111458 (rank : 247)
Query Neighborhood Hits	437	Target Neighborhood Hits	1537	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CCD55_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.061757 (rank : 372)
Query Neighborhood Hits	437	Target Neighborhood Hits	519	Shared Neighborhood Hits	80
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CJ078_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.067455 (rank : 348)
Query Neighborhood Hits	437	Target Neighborhood Hits	559	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.080398 (rank : 310)
Query Neighborhood Hits	437	Target Neighborhood Hits	385	Shared Neighborhood Hits	67
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CPNE1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.085435 (rank : 295)
Query Neighborhood Hits	437	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.103589 (rank : 264)
Query Neighborhood Hits	437	Target Neighborhood Hits	83	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.107235 (rank : 258)
Query Neighborhood Hits	437	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.107031 (rank : 259)
Query Neighborhood Hits	437	Target Neighborhood Hits	82	Shared Neighborhood Hits	55
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.121999 (rank : 233)
Query Neighborhood Hits	437	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.121729 (rank : 236)
Query Neighborhood Hits	437	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE4_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.069050 (rank : 341)
Query Neighborhood Hits	437	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.067491 (rank : 346)
Query Neighborhood Hits	437	Target Neighborhood Hits	67	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CPNE5_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.111511 (rank : 246)
Query Neighborhood Hits	437	Target Neighborhood Hits	88	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.111627 (rank : 245)
Query Neighborhood Hits	437	Target Neighborhood Hits	86	Shared Neighborhood Hits	58
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE6_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.076476 (rank : 315)
Query Neighborhood Hits	437	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.075970 (rank : 317)
Query Neighborhood Hits	437	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE7_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.094921 (rank : 277)
Query Neighborhood Hits	437	Target Neighborhood Hits	92	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

CPNE8_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.107494 (rank : 257)
Query Neighborhood Hits	437	Target Neighborhood Hits	86	Shared Neighborhood Hits	58
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.104617 (rank : 262)
Query Neighborhood Hits	437	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CS016_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.055870 (rank : 396)
Query Neighborhood Hits	437	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CYLC2_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.051309 (rank : 441)
Query Neighborhood Hits	437	Target Neighborhood Hits	223	Shared Neighborhood Hits	32
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DEK_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.053190 (rank : 429)
Query Neighborhood Hits	437	Target Neighborhood Hits	280	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DMP1_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.053868 (rank : 422)
Query Neighborhood Hits	437	Target Neighborhood Hits	498	Shared Neighborhood Hits	65
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

EM55_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.113883 (rank : 243)
Query Neighborhood Hits	437	Target Neighborhood Hits	228	Shared Neighborhood Hits	109
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

ENL_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.081820 (rank : 305)
Query Neighborhood Hits	437	Target Neighborhood Hits	305	Shared Neighborhood Hits	57
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

GNAS3_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.061388 (rank : 377)
Query Neighborhood Hits	437	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

GNAS3_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.052161 (rank : 435)
Query Neighborhood Hits	437	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

GPTC8_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.102123 (rank : 266)
Query Neighborhood Hits	437	Target Neighborhood Hits	366	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

GRASP_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.097078 (rank : 274)
Query Neighborhood Hits	437	Target Neighborhood Hits	147	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.092579 (rank : 281)
Query Neighborhood Hits	437	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRP3_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.053208 (rank : 428)
Query Neighborhood Hits	437	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.054392 (rank : 417)
Query Neighborhood Hits	437	Target Neighborhood Hits	674	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HIRP3_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.055340 (rank : 405)
Query Neighborhood Hits	437	Target Neighborhood Hits	323	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

KGUA_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.067368 (rank : 349)
Query Neighborhood Hits	437	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.067698 (rank : 345)
Query Neighborhood Hits	437	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KI67_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.060969 (rank : 380)
Query Neighborhood Hits	437	Target Neighborhood Hits	581	Shared Neighborhood Hits	80
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LAD1_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.060332 (rank : 383)
Query Neighborhood Hits	437	Target Neighborhood Hits	441	Shared Neighborhood Hits	65
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LAP2_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.058413 (rank : 387)
Query Neighborhood Hits	437	Target Neighborhood Hits	499	Shared Neighborhood Hits	95
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.053594 (rank : 424)
Query Neighborhood Hits	437	Target Neighborhood Hits	482	Shared Neighborhood Hits	88
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LDB3_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.055844 (rank : 397)
Query Neighborhood Hits	437	Target Neighborhood Hits	497	Shared Neighborhood Hits	89
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.057738 (rank : 390)
Query Neighborhood Hits	437	Target Neighborhood Hits	510	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LIN7A_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.215093 (rank : 135)
Query Neighborhood Hits	437	Target Neighborhood Hits	193	Shared Neighborhood Hits	121
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.215110 (rank : 134)
Query Neighborhood Hits	437	Target Neighborhood Hits	193	Shared Neighborhood Hits	121
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LRRC7_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.058549 (rank : 385)
Query Neighborhood Hits	437	Target Neighborhood Hits	423	Shared Neighborhood Hits	88
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.057959 (rank : 388)
Query Neighborhood Hits	437	Target Neighborhood Hits	416	Shared Neighborhood Hits	89
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MAP1B_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.050871 (rank : 444)
Query Neighborhood Hits	437	Target Neighborhood Hits	977	Shared Neighborhood Hits	85
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MARCS_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.068364 (rank : 343)
Query Neighborhood Hits	437	Target Neighborhood Hits	204	Shared Neighborhood Hits	40
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.057772 (rank : 389)
Query Neighborhood Hits	437	Target Neighborhood Hits	227	Shared Neighborhood Hits	43
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MELPH_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.081528 (rank : 306)
Query Neighborhood Hits	437	Target Neighborhood Hits	145	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MELPH_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.083302 (rank : 300)
Query Neighborhood Hits	437	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

MINT_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.063330 (rank : 367)
Query Neighborhood Hits	437	Target Neighborhood Hits	1514	Shared Neighborhood Hits	131
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MPP2_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.089889 (rank : 288)
Query Neighborhood Hits	437	Target Neighborhood Hits	173	Shared Neighborhood Hits	77
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.090269 (rank : 286)
Query Neighborhood Hits	437	Target Neighborhood Hits	189	Shared Neighborhood Hits	84
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP3_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.133413 (rank : 225)
Query Neighborhood Hits	437	Target Neighborhood Hits	171	Shared Neighborhood Hits	107
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.134396 (rank : 224)
Query Neighborhood Hits	437	Target Neighborhood Hits	165	Shared Neighborhood Hits	107
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP6_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.091635 (rank : 283)
Query Neighborhood Hits	437	Target Neighborhood Hits	180	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.093024 (rank : 280)
Query Neighborhood Hits	437	Target Neighborhood Hits	187	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MUC7_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.079160 (rank : 311)
Query Neighborhood Hits	437	Target Neighborhood Hits	538	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MYOF_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.212928 (rank : 137)
Query Neighborhood Hits	437	Target Neighborhood Hits	147	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

NEUM_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.055169 (rank : 408)
Query Neighborhood Hits	437	Target Neighborhood Hits	132	Shared Neighborhood Hits	32
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.062802 (rank : 368)
Query Neighborhood Hits	437	Target Neighborhood Hits	149	Shared Neighborhood Hits	34
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NUCKS_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.050324 (rank : 448)
Query Neighborhood Hits	437	Target Neighborhood Hits	143	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

OTOF_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.178038 (rank : 177)
Query Neighborhood Hits	437	Target Neighborhood Hits	168	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.177759 (rank : 178)
Query Neighborhood Hits	437	Target Neighborhood Hits	196	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PA24C_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.052504 (rank : 432)
Query Neighborhood Hits	437	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UP65, O75457, Q9UG68	Gene names	PLA2G4C
Domain Architecture
Description	Cytosolic phospholipase A2 gamma precursor (EC 3.1.1.4) (cPLA2-gamma) (Phospholipase A2 group IVC).

PDLI1_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.051892 (rank : 438)
Query Neighborhood Hits	437	Target Neighborhood Hits	242	Shared Neighborhood Hits	63
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.055191 (rank : 407)
Query Neighborhood Hits	437	Target Neighborhood Hits	213	Shared Neighborhood Hits	72
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI2_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.091741 (rank : 282)
Query Neighborhood Hits	437	Target Neighborhood Hits	245	Shared Neighborhood Hits	79
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI2_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.083204 (rank : 301)
Query Neighborhood Hits	437	Target Neighborhood Hits	220	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI3_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.054344 (rank : 418)
Query Neighborhood Hits	437	Target Neighborhood Hits	199	Shared Neighborhood Hits	68
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.055616 (rank : 401)
Query Neighborhood Hits	437	Target Neighborhood Hits	245	Shared Neighborhood Hits	77
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.054631 (rank : 416)
Query Neighborhood Hits	437	Target Neighborhood Hits	233	Shared Neighborhood Hits	71
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI5_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.050742 (rank : 445)
Query Neighborhood Hits	437	Target Neighborhood Hits	322	Shared Neighborhood Hits	88
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDZ11_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.180630 (rank : 170)
Query Neighborhood Hits	437	Target Neighborhood Hits	160	Shared Neighborhood Hits	97
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.179679 (rank : 173)
Query Neighborhood Hits	437	Target Neighborhood Hits	154	Shared Neighborhood Hits	92
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZD1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.176724 (rank : 180)
Query Neighborhood Hits	437	Target Neighborhood Hits	190	Shared Neighborhood Hits	103
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD3_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.161089 (rank : 195)
Query Neighborhood Hits	437	Target Neighborhood Hits	180	Shared Neighborhood Hits	101
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD6_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.050637 (rank : 446)
Query Neighborhood Hits	437	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PDZD8_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.080970 (rank : 308)
Query Neighborhood Hits	437	Target Neighborhood Hits	185	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PDZK4_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.141257 (rank : 215)
Query Neighborhood Hits	437	Target Neighborhood Hits	165	Shared Neighborhood Hits	94
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PI4KA_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.061669 (rank : 374)
Query Neighborhood Hits	437	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PI4KB_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.058423 (rank : 386)
Query Neighborhood Hits	437	Target Neighborhood Hits	79	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

PI4KB_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.054894 (rank : 412)
Query Neighborhood Hits	437	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

PININ_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.050101 (rank : 450)
Query Neighborhood Hits	437	Target Neighborhood Hits	753	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PK3C3_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.062390 (rank : 369)
Query Neighborhood Hits	437	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.062176 (rank : 370)
Query Neighborhood Hits	437	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PK3CA_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.070069 (rank : 338)
Query Neighborhood Hits	437	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.069961 (rank : 340)
Query Neighborhood Hits	437	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CB_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.065932 (rank : 357)
Query Neighborhood Hits	437	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.065978 (rank : 356)
Query Neighborhood Hits	437	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CD_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.066688 (rank : 351)
Query Neighborhood Hits	437	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.066552 (rank : 352)
Query Neighborhood Hits	437	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CG_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.071796 (rank : 332)
Query Neighborhood Hits	437	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.071621 (rank : 333)
Query Neighborhood Hits	437	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PLCD1_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.081382 (rank : 307)
Query Neighborhood Hits	437	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.054758 (rank : 414)
Query Neighborhood Hits	437	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PRAX_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.053921 (rank : 421)
Query Neighborhood Hits	437	Target Neighborhood Hits	215	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.055109 (rank : 410)
Query Neighborhood Hits	437	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRB4S_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.064046 (rank : 364)
Query Neighborhood Hits	437	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.073030 (rank : 323)
Query Neighborhood Hits	437	Target Neighborhood Hits	764	Shared Neighborhood Hits	78
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.072127 (rank : 330)
Query Neighborhood Hits	437	Target Neighborhood Hits	624	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.070068 (rank : 339)
Query Neighborhood Hits	437	Target Neighborhood Hits	385	Shared Neighborhood Hits	49
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.055155 (rank : 409)
Query Neighborhood Hits	437	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.063551 (rank : 366)
Query Neighborhood Hits	437	Target Neighborhood Hits	460	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PSCBP_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.076661 (rank : 314)
Query Neighborhood Hits	437	Target Neighborhood Hits	123	Shared Neighborhood Hits	74
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PSCBP_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.090340 (rank : 285)
Query Neighborhood Hits	437	Target Neighborhood Hits	118	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RAPH1_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.051397 (rank : 440)
Query Neighborhood Hits	437	Target Neighborhood Hits	593	Shared Neighborhood Hits	63
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RASA2_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.219800 (rank : 128)
Query Neighborhood Hits	437	Target Neighborhood Hits	157	Shared Neighborhood Hits	72
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.220401 (rank : 126)
Query Neighborhood Hits	437	Target Neighborhood Hits	159	Shared Neighborhood Hits	71
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA3_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.225708 (rank : 115)
Query Neighborhood Hits	437	Target Neighborhood Hits	166	Shared Neighborhood Hits	75
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.172584 (rank : 184)
Query Neighborhood Hits	437	Target Neighborhood Hits	144	Shared Neighborhood Hits	66
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RFIP1_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.104702 (rank : 261)
Query Neighborhood Hits	437	Target Neighborhood Hits	236	Shared Neighborhood Hits	71
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP1_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.099647 (rank : 271)
Query Neighborhood Hits	437	Target Neighborhood Hits	152	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP2_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.203632 (rank : 140)
Query Neighborhood Hits	437	Target Neighborhood Hits	97	Shared Neighborhood Hits	65
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

RGS3_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.057379 (rank : 392)
Query Neighborhood Hits	437	Target Neighborhood Hits	1621	Shared Neighborhood Hits	125
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHPN1_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.084580 (rank : 298)
Query Neighborhood Hits	437	Target Neighborhood Hits	158	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.089973 (rank : 287)
Query Neighborhood Hits	437	Target Neighborhood Hits	154	Shared Neighborhood Hits	83
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RPGF2_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.085298 (rank : 296)
Query Neighborhood Hits	437	Target Neighborhood Hits	242	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

RPGF6_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.101745 (rank : 268)
Query Neighborhood Hits	437	Target Neighborhood Hits	266	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

RSRC1_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.076868 (rank : 313)
Query Neighborhood Hits	437	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

RSRC1_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.052310 (rank : 433)
Query Neighborhood Hits	437	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SELPL_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.051972 (rank : 437)
Query Neighborhood Hits	437	Target Neighborhood Hits	588	Shared Neighborhood Hits	59
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SET1A_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.061657 (rank : 375)
Query Neighborhood Hits	437	Target Neighborhood Hits	690	Shared Neighborhood Hits	80
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SFRIP_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.087708 (rank : 292)
Query Neighborhood Hits	437	Target Neighborhood Hits	530	Shared Neighborhood Hits	100
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SHAN2_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.076132 (rank : 316)
Query Neighborhood Hits	437	Target Neighborhood Hits	346	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.072931 (rank : 324)
Query Neighborhood Hits	437	Target Neighborhood Hits	446	Shared Neighborhood Hits	110
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SLC2B_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.068453 (rank : 342)
Query Neighborhood Hits	437	Target Neighborhood Hits	214	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

SRRM1_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.126294 (rank : 231)
Query Neighborhood Hits	437	Target Neighborhood Hits	690	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

STXB4_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.144327 (rank : 212)
Query Neighborhood Hits	437	Target Neighborhood Hits	616	Shared Neighborhood Hits	101
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.143201 (rank : 213)
Query Neighborhood Hits	437	Target Neighborhood Hits	629	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYP2L_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.097147 (rank : 273)
Query Neighborhood Hits	437	Target Neighborhood Hits	400	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYP2L_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.066205 (rank : 355)
Query Neighborhood Hits	437	Target Neighborhood Hits	289	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYT13_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.364573 (rank : 60)
Query Neighborhood Hits	437	Target Neighborhood Hits	76	Shared Neighborhood Hits	63
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.366375 (rank : 59)
Query Neighborhood Hits	437	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

T2FA_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.055354 (rank : 404)
Query Neighborhood Hits	437	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TAC2N_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.199928 (rank : 144)
Query Neighborhood Hits	437	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.198608 (rank : 147)
Query Neighborhood Hits	437	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TCOF_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.074178 (rank : 318)
Query Neighborhood Hits	437	Target Neighborhood Hits	543	Shared Neighborhood Hits	77
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.082201 (rank : 303)
Query Neighborhood Hits	437	Target Neighborhood Hits	471	Shared Neighborhood Hits	76
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TGON1_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.053234 (rank : 427)
Query Neighborhood Hits	437	Target Neighborhood Hits	243	Shared Neighborhood Hits	43
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

THOC2_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.051245 (rank : 442)
Query Neighborhood Hits	437	Target Neighborhood Hits	337	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TMAP1_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.052262 (rank : 434)
Query Neighborhood Hits	437	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TP53B_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.055664 (rank : 400)
Query Neighborhood Hits	437	Target Neighborhood Hits	644	Shared Neighborhood Hits	65
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRDN_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.056916 (rank : 395)
Query Neighborhood Hits	437	Target Neighborhood Hits	542	Shared Neighborhood Hits	57
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRIPC_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.050010 (rank : 451)
Query Neighborhood Hits	437	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

TX1B3_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.177436 (rank : 179)
Query Neighborhood Hits	437	Target Neighborhood Hits	161	Shared Neighborhood Hits	105
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.173525 (rank : 182)
Query Neighborhood Hits	437	Target Neighborhood Hits	158	Shared Neighborhood Hits	102
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

VCX1_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.052116 (rank : 436)
Query Neighborhood Hits	437	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.055069 (rank : 411)
Query Neighborhood Hits	437	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.055422 (rank : 402)
Query Neighborhood Hits	437	Target Neighborhood Hits	139	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

WASIP_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.053484 (rank : 426)
Query Neighborhood Hits	437	Target Neighborhood Hits	458	Shared Neighborhood Hits	46
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WWC1_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.064838 (rank : 361)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.085221 (rank : 297)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	44
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWP1_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.054137 (rank : 420)
Query Neighborhood Hits	437	Target Neighborhood Hits	262	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

YLPM1_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.054197 (rank : 419)
Query Neighborhood Hits	437	Target Neighborhood Hits	670	Shared Neighborhood Hits	74
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YTDC1_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.053564 (rank : 425)
Query Neighborhood Hits	437	Target Neighborhood Hits	458	Shared Neighborhood Hits	71
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZC313_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.067488 (rank : 347)
Query Neighborhood Hits	437	Target Neighborhood Hits	772	Shared Neighborhood Hits	94
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZO1_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.178728 (rank : 176)
Query Neighborhood Hits	437	Target Neighborhood Hits	474	Shared Neighborhood Hits	136
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.180852 (rank : 169)
Query Neighborhood Hits	437	Target Neighborhood Hits	453	Shared Neighborhood Hits	147
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO3_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.189859 (rank : 158)
Query Neighborhood Hits	437	Target Neighborhood Hits	219	Shared Neighborhood Hits	115
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

Hits sorted by NC score

RIMS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	437	Target Neighborhood Hits	437	Shared Neighborhood Hits	437
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIMS2_HUMAN
NC score	0.943046 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	437	Target Neighborhood Hits	342	Shared Neighborhood Hits	228
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.940040 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	437	Target Neighborhood Hits	376	Shared Neighborhood Hits	230
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS4_MOUSE
NC score	0.871401 (rank : 4)	θ value	4.81303e-86 (rank : 6)
Query Neighborhood Hits	437	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.870825 (rank : 5)	θ value	8.20983e-86 (rank : 7)
Query Neighborhood Hits	437	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS3_HUMAN
NC score	0.856445 (rank : 6)	θ value	1.64657e-102 (rank : 4)
Query Neighborhood Hits	437	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
NC score	0.851146 (rank : 7)	θ value	4.79078e-102 (rank : 5)
Query Neighborhood Hits	437	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

SYTL1_HUMAN
NC score	0.600015 (rank : 8)	θ value	2.28291e-11 (rank : 19)
Query Neighborhood Hits	437	Target Neighborhood Hits	227	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL4_HUMAN
NC score	0.596956 (rank : 9)	θ value	1.58096e-12 (rank : 12)
Query Neighborhood Hits	437	Target Neighborhood Hits	138	Shared Neighborhood Hits	85
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

DOC2A_MOUSE
NC score	0.595713 (rank : 10)	θ value	7.84624e-12 (rank : 14)
Query Neighborhood Hits	437	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

SYTL3_MOUSE
NC score	0.595288 (rank : 11)	θ value	4.0297e-08 (rank : 50)
Query Neighborhood Hits	437	Target Neighborhood Hits	110	Shared Neighborhood Hits	81
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYTL5_HUMAN
NC score	0.594561 (rank : 12)	θ value	3.89403e-11 (rank : 21)
Query Neighborhood Hits	437	Target Neighborhood Hits	237	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL4_MOUSE
NC score	0.594376 (rank : 13)	θ value	9.26847e-13 (rank : 11)
Query Neighborhood Hits	437	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

DOC2A_HUMAN
NC score	0.592815 (rank : 14)	θ value	6.64225e-11 (rank : 23)
Query Neighborhood Hits	437	Target Neighborhood Hits	144	Shared Neighborhood Hits	97
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

RP3A_HUMAN
NC score	0.587796 (rank : 15)	θ value	1.47974e-10 (rank : 28)
Query Neighborhood Hits	437	Target Neighborhood Hits	305	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2B_HUMAN
NC score	0.584337 (rank : 16)	θ value	1.133e-10 (rank : 25)
Query Neighborhood Hits	437	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYTL5_MOUSE
NC score	0.583815 (rank : 17)	θ value	1.9326e-10 (rank : 31)
Query Neighborhood Hits	437	Target Neighborhood Hits	154	Shared Neighborhood Hits	97
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

DOC2B_MOUSE
NC score	0.582973 (rank : 18)	θ value	1.133e-10 (rank : 26)
Query Neighborhood Hits	437	Target Neighborhood Hits	169	Shared Neighborhood Hits	100
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT7_MOUSE
NC score	0.581318 (rank : 19)	θ value	1.63604e-09 (rank : 45)
Query Neighborhood Hits	437	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

RP3A_MOUSE
NC score	0.575067 (rank : 20)	θ value	3.29651e-10 (rank : 33)
Query Neighborhood Hits	437	Target Neighborhood Hits	510	Shared Neighborhood Hits	130
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT3_HUMAN
NC score	0.571826 (rank : 21)	θ value	4.59992e-12 (rank : 13)
Query Neighborhood Hits	437	Target Neighborhood Hits	145	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYTL1_MOUSE
NC score	0.571731 (rank : 22)	θ value	8.67504e-11 (rank : 24)
Query Neighborhood Hits	437	Target Neighborhood Hits	314	Shared Neighborhood Hits	93
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYT7_HUMAN
NC score	0.568479 (rank : 23)	θ value	2.79066e-09 (rank : 47)
Query Neighborhood Hits	437	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT3_MOUSE
NC score	0.567906 (rank : 24)	θ value	2.28291e-11 (rank : 18)
Query Neighborhood Hits	437	Target Neighborhood Hits	147	Shared Neighborhood Hits	95
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYTL2_HUMAN
NC score	0.566108 (rank : 25)	θ value	9.59137e-10 (rank : 40)
Query Neighborhood Hits	437	Target Neighborhood Hits	248	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
NC score	0.561191 (rank : 26)	θ value	1.9326e-10 (rank : 30)
Query Neighborhood Hits	437	Target Neighborhood Hits	253	Shared Neighborhood Hits	109
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYT2_MOUSE
NC score	0.558894 (rank : 27)	θ value	2.28291e-11 (rank : 17)
Query Neighborhood Hits	437	Target Neighborhood Hits	143	Shared Neighborhood Hits	99
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.558650 (rank : 28)	θ value	2.98157e-11 (rank : 20)
Query Neighborhood Hits	437	Target Neighborhood Hits	142	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT6_MOUSE
NC score	0.555348 (rank : 29)	θ value	7.34386e-10 (rank : 38)
Query Neighborhood Hits	437	Target Neighborhood Hits	132	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
NC score	0.554373 (rank : 30)	θ value	1.25267e-09 (rank : 44)
Query Neighborhood Hits	437	Target Neighborhood Hits	138	Shared Neighborhood Hits	98
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT9_MOUSE
NC score	0.553954 (rank : 31)	θ value	5.08577e-11 (rank : 22)
Query Neighborhood Hits	437	Target Neighborhood Hits	148	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

PCLO_MOUSE
NC score	0.552841 (rank : 32)	θ value	1.57365e-28 (rank : 8)
Query Neighborhood Hits	437	Target Neighborhood Hits	2275	Shared Neighborhood Hits	299
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYT9_HUMAN
NC score	0.550947 (rank : 33)	θ value	7.34386e-10 (rank : 39)
Query Neighborhood Hits	437	Target Neighborhood Hits	144	Shared Neighborhood Hits	98
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT10_HUMAN
NC score	0.549392 (rank : 34)	θ value	4.30538e-10 (rank : 35)
Query Neighborhood Hits	437	Target Neighborhood Hits	134	Shared Neighborhood Hits	97
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT1_HUMAN
NC score	0.548262 (rank : 35)	θ value	1.25267e-09 (rank : 42)
Query Neighborhood Hits	437	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.548248 (rank : 36)	θ value	1.25267e-09 (rank : 43)
Query Neighborhood Hits	437	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT10_MOUSE
NC score	0.547302 (rank : 37)	θ value	2.13673e-09 (rank : 46)
Query Neighborhood Hits	437	Target Neighborhood Hits	133	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

DOC2G_MOUSE
NC score	0.543570 (rank : 38)	θ value	9.92553e-07 (rank : 56)
Query Neighborhood Hits	437	Target Neighborhood Hits	125	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

FA62A_HUMAN
NC score	0.543376 (rank : 39)	θ value	1.9326e-10 (rank : 29)
Query Neighborhood Hits	437	Target Neighborhood Hits	168	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
NC score	0.541624 (rank : 40)	θ value	8.97725e-08 (rank : 51)
Query Neighborhood Hits	437	Target Neighborhood Hits	155	Shared Neighborhood Hits	97
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT5_HUMAN
NC score	0.540879 (rank : 41)	θ value	1.17247e-07 (rank : 52)
Query Neighborhood Hits	437	Target Neighborhood Hits	138	Shared Neighborhood Hits	98
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
NC score	0.535291 (rank : 42)	θ value	3.08544e-08 (rank : 49)
Query Neighborhood Hits	437	Target Neighborhood Hits	140	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT4_HUMAN
NC score	0.530474 (rank : 43)	θ value	1.99992e-07 (rank : 53)
Query Neighborhood Hits	437	Target Neighborhood Hits	121	Shared Neighborhood Hits	95
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT12_HUMAN
NC score	0.524319 (rank : 44)	θ value	8.40245e-06 (rank : 62)
Query Neighborhood Hits	437	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
NC score	0.524316 (rank : 45)	θ value	3.77169e-06 (rank : 60)
Query Neighborhood Hits	437	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT4_MOUSE
NC score	0.523947 (rank : 46)	θ value	5.81887e-07 (rank : 55)
Query Neighborhood Hits	437	Target Neighborhood Hits	123	Shared Neighborhood Hits	92
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT11_MOUSE
NC score	0.523892 (rank : 47)	θ value	9.92553e-07 (rank : 57)
Query Neighborhood Hits	437	Target Neighborhood Hits	116	Shared Neighborhood Hits	92
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
NC score	0.522455 (rank : 48)	θ value	4.92598e-06 (rank : 61)
Query Neighborhood Hits	437	Target Neighborhood Hits	113	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

PCLO_HUMAN
NC score	0.519112 (rank : 49)	θ value	2.77775e-25 (rank : 9)
Query Neighborhood Hits	437	Target Neighborhood Hits	2046	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYT15_HUMAN
NC score	0.504000 (rank : 50)	θ value	2.44474e-05 (rank : 68)
Query Neighborhood Hits	437	Target Neighborhood Hits	112	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT8_MOUSE
NC score	0.487569 (rank : 51)	θ value	0.00509761 (rank : 111)
Query Neighborhood Hits	437	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYT15_MOUSE
NC score	0.469075 (rank : 52)	θ value	0.000121331 (rank : 80)
Query Neighborhood Hits	437	Target Neighborhood Hits	100	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

P3C2B_HUMAN
NC score	0.449884 (rank : 53)	θ value	5.43371e-13 (rank : 10)
Query Neighborhood Hits	437	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

RASL2_HUMAN
NC score	0.421927 (rank : 54)	θ value	1.29631e-06 (rank : 58)
Query Neighborhood Hits	437	Target Neighborhood Hits	161	Shared Neighborhood Hits	92
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

P3C2A_HUMAN
NC score	0.400784 (rank : 55)	θ value	1.33837e-11 (rank : 15)
Query Neighborhood Hits	437	Target Neighborhood Hits	188	Shared Neighborhood Hits	79
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
NC score	0.395278 (rank : 56)	θ value	2.28291e-11 (rank : 16)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	77
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

SYT14_MOUSE
NC score	0.374994 (rank : 57)	θ value	0.0736092 (rank : 170)
Query Neighborhood Hits	437	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_HUMAN
NC score	0.373268 (rank : 58)	θ value	0.21417 (rank : 199)
Query Neighborhood Hits	437	Target Neighborhood Hits	81	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT13_MOUSE
NC score	0.366375 (rank : 59)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	437	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_HUMAN
NC score	0.364573 (rank : 60)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	437	Target Neighborhood Hits	76	Shared Neighborhood Hits	63
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

UN13D_HUMAN
NC score	0.347284 (rank : 61)	θ value	0.0736092 (rank : 171)
Query Neighborhood Hits	437	Target Neighborhood Hits	117	Shared Neighborhood Hits	80
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

RASL1_HUMAN
NC score	0.321808 (rank : 62)	θ value	0.0113563 (rank : 121)
Query Neighborhood Hits	437	Target Neighborhood Hits	142	Shared Neighborhood Hits	80
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
NC score	0.308454 (rank : 63)	θ value	0.0563607 (rank : 160)
Query Neighborhood Hits	437	Target Neighborhood Hits	148	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

UN13A_HUMAN
NC score	0.306633 (rank : 64)	θ value	3.19293e-05 (rank : 70)
Query Neighborhood Hits	437	Target Neighborhood Hits	285	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_MOUSE
NC score	0.302854 (rank : 65)	θ value	1.43324e-05 (rank : 67)
Query Neighborhood Hits	437	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

BAIP3_HUMAN
NC score	0.301360 (rank : 66)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	437	Target Neighborhood Hits	108	Shared Neighborhood Hits	75
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

UN13B_HUMAN
NC score	0.301013 (rank : 67)	θ value	1.09739e-05 (rank : 64)
Query Neighborhood Hits	437	Target Neighborhood Hits	217	Shared Neighborhood Hits	84
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PDZD2_HUMAN
NC score	0.295567 (rank : 68)	θ value	4.1701e-05 (rank : 72)
Query Neighborhood Hits	437	Target Neighborhood Hits	772	Shared Neighborhood Hits	176
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

BAIP3_MOUSE
NC score	0.293240 (rank : 69)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	437	Target Neighborhood Hits	112	Shared Neighborhood Hits	78
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

USH1C_HUMAN
NC score	0.282452 (rank : 70)	θ value	9.29e-05 (rank : 76)
Query Neighborhood Hits	437	Target Neighborhood Hits	327	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

MPDZ_HUMAN
NC score	0.281669 (rank : 71)	θ value	1.09739e-05 (rank : 63)
Query Neighborhood Hits	437	Target Neighborhood Hits	261	Shared Neighborhood Hits	129
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

K0528_MOUSE
NC score	0.281529 (rank : 72)	θ value	1.81305 (rank : 291)
Query Neighborhood Hits	437	Target Neighborhood Hits	102	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_HUMAN
NC score	0.280026 (rank : 73)	θ value	1.81305 (rank : 290)
Query Neighborhood Hits	437	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

MPDZ_MOUSE
NC score	0.278898 (rank : 74)	θ value	0.000270298 (rank : 86)
Query Neighborhood Hits	437	Target Neighborhood Hits	298	Shared Neighborhood Hits	131
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

INADL_HUMAN
NC score	0.278114 (rank : 75)	θ value	7.1131e-05 (rank : 74)
Query Neighborhood Hits	437	Target Neighborhood Hits	260	Shared Neighborhood Hits	127
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
NC score	0.277073 (rank : 76)	θ value	0.000158464 (rank : 81)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	132
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

WHRN_MOUSE
NC score	0.274470 (rank : 77)	θ value	1.09739e-05 (rank : 65)
Query Neighborhood Hits	437	Target Neighborhood Hits	412	Shared Neighborhood Hits	138
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

USH1C_MOUSE
NC score	0.271461 (rank : 78)	θ value	9.29e-05 (rank : 77)
Query Neighborhood Hits	437	Target Neighborhood Hits	557	Shared Neighborhood Hits	145
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

WHRN_HUMAN
NC score	0.270579 (rank : 79)	θ value	4.1701e-05 (rank : 73)
Query Neighborhood Hits	437	Target Neighborhood Hits	325	Shared Neighborhood Hits	134
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

PA24D_MOUSE
NC score	0.270491 (rank : 80)	θ value	0.0961366 (rank : 181)
Query Neighborhood Hits	437	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

IL16_HUMAN
NC score	0.269004 (rank : 81)	θ value	0.0193708 (rank : 128)
Query Neighborhood Hits	437	Target Neighborhood Hits	207	Shared Neighborhood Hits	119
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PAR3L_HUMAN
NC score	0.268044 (rank : 82)	θ value	0.00228821 (rank : 99)
Query Neighborhood Hits	437	Target Neighborhood Hits	297	Shared Neighborhood Hits	122
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PARD3_HUMAN
NC score	0.267976 (rank : 83)	θ value	0.00035302 (rank : 87)
Query Neighborhood Hits	437	Target Neighborhood Hits	312	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
NC score	0.266829 (rank : 84)	θ value	0.00175202 (rank : 97)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	134
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

NED4L_HUMAN
NC score	0.258811 (rank : 85)	θ value	0.00020696 (rank : 84)
Query Neighborhood Hits	437	Target Neighborhood Hits	238	Shared Neighborhood Hits	99
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

IL16_MOUSE
NC score	0.255012 (rank : 86)	θ value	0.0431538 (rank : 144)
Query Neighborhood Hits	437	Target Neighborhood Hits	189	Shared Neighborhood Hits	108
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

NED4L_MOUSE
NC score	0.253875 (rank : 87)	θ value	0.00020696 (rank : 85)
Query Neighborhood Hits	437	Target Neighborhood Hits	231	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

LIN7B_HUMAN
NC score	0.251415 (rank : 88)	θ value	0.0431538 (rank : 145)
Query Neighborhood Hits	437	Target Neighborhood Hits	200	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.249905 (rank : 89)	θ value	0.0563607 (rank : 155)
Query Neighborhood Hits	437	Target Neighborhood Hits	200	Shared Neighborhood Hits	123
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

SYJ2B_HUMAN
NC score	0.247405 (rank : 90)	θ value	0.47712 (rank : 224)
Query Neighborhood Hits	437	Target Neighborhood Hits	162	Shared Neighborhood Hits	113
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

LIN7C_HUMAN
NC score	0.246690 (rank : 91)	θ value	0.125558 (rank : 184)
Query Neighborhood Hits	437	Target Neighborhood Hits	198	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.246690 (rank : 92)	θ value	0.125558 (rank : 185)
Query Neighborhood Hits	437	Target Neighborhood Hits	198	Shared Neighborhood Hits	123
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

P3C2G_MOUSE
NC score	0.244867 (rank : 93)	θ value	3.77169e-06 (rank : 59)
Query Neighborhood Hits	437	Target Neighborhood Hits	113	Shared Neighborhood Hits	63
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

LNX2_HUMAN
NC score	0.238899 (rank : 94)	θ value	0.00509761 (rank : 109)
Query Neighborhood Hits	437	Target Neighborhood Hits	389	Shared Neighborhood Hits	120
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
NC score	0.238471 (rank : 95)	θ value	0.00390308 (rank : 104)
Query Neighborhood Hits	437	Target Neighborhood Hits	407	Shared Neighborhood Hits	125
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

SNTA1_HUMAN
NC score	0.238401 (rank : 96)	θ value	9.29e-05 (rank : 75)
Query Neighborhood Hits	437	Target Neighborhood Hits	186	Shared Neighborhood Hits	111
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

PA24D_HUMAN
NC score	0.237655 (rank : 97)	θ value	1.38821 (rank : 273)
Query Neighborhood Hits	437	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

LNX1_MOUSE
NC score	0.236393 (rank : 98)	θ value	0.0148317 (rank : 124)
Query Neighborhood Hits	437	Target Neighborhood Hits	377	Shared Neighborhood Hits	124
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PDZD7_HUMAN
NC score	0.236056 (rank : 99)	θ value	0.0961366 (rank : 182)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	111
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

NEDD4_HUMAN
NC score	0.235665 (rank : 100)	θ value	0.0148317 (rank : 125)
Query Neighborhood Hits	437	Target Neighborhood Hits	214	Shared Neighborhood Hits	97
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

DLG2_MOUSE
NC score	0.235507 (rank : 101)	θ value	0.000461057 (rank : 89)
Query Neighborhood Hits	437	Target Neighborhood Hits	271	Shared Neighborhood Hits	127
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG4_MOUSE
NC score	0.235185 (rank : 102)	θ value	0.00298849 (rank : 102)
Query Neighborhood Hits	437	Target Neighborhood Hits	282	Shared Neighborhood Hits	121
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.234755 (rank : 103)	θ value	0.00298849 (rank : 101)
Query Neighborhood Hits	437	Target Neighborhood Hits	286	Shared Neighborhood Hits	120
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_HUMAN
NC score	0.234387 (rank : 104)	θ value	0.000602161 (rank : 91)
Query Neighborhood Hits	437	Target Neighborhood Hits	279	Shared Neighborhood Hits	129
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

GRIP2_HUMAN
NC score	0.233817 (rank : 105)	θ value	0.0113563 (rank : 119)
Query Neighborhood Hits	437	Target Neighborhood Hits	256	Shared Neighborhood Hits	133
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

SNTG2_HUMAN
NC score	0.232570 (rank : 106)	θ value	0.00665767 (rank : 115)
Query Neighborhood Hits	437	Target Neighborhood Hits	191	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

GOPC_MOUSE
NC score	0.231539 (rank : 107)	θ value	0.000461057 (rank : 90)
Query Neighborhood Hits	437	Target Neighborhood Hits	323	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

DLG1_HUMAN
NC score	0.227252 (rank : 108)	θ value	0.00665767 (rank : 112)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	124
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
NC score	0.227192 (rank : 109)	θ value	0.00509761 (rank : 106)
Query Neighborhood Hits	437	Target Neighborhood Hits	285	Shared Neighborhood Hits	122
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DYSF_HUMAN
NC score	0.226952 (rank : 110)	θ value	6.88961 (rank : 375)
Query Neighborhood Hits	437	Target Neighborhood Hits	170	Shared Neighborhood Hits	95
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DLG3_MOUSE
NC score	0.226369 (rank : 111)	θ value	0.00134147 (rank : 95)
Query Neighborhood Hits	437	Target Neighborhood Hits	274	Shared Neighborhood Hits	123
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

GRIP1_HUMAN
NC score	0.226343 (rank : 112)	θ value	0.62314 (rank : 229)
Query Neighborhood Hits	437	Target Neighborhood Hits	231	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SNTA1_MOUSE
NC score	0.226116 (rank : 113)	θ value	0.000786445 (rank : 92)
Query Neighborhood Hits	437	Target Neighborhood Hits	170	Shared Neighborhood Hits	107
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTB2_HUMAN
NC score	0.226041 (rank : 114)	θ value	0.0113563 (rank : 122)
Query Neighborhood Hits	437	Target Neighborhood Hits	180	Shared Neighborhood Hits	107
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

RASA3_HUMAN
NC score	0.225708 (rank : 115)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	437	Target Neighborhood Hits	166	Shared Neighborhood Hits	75
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

DLG3_HUMAN
NC score	0.225708 (rank : 116)	θ value	0.00134147 (rank : 94)
Query Neighborhood Hits	437	Target Neighborhood Hits	269	Shared Neighborhood Hits	123
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

GOPC_HUMAN
NC score	0.224753 (rank : 117)	θ value	0.00298849 (rank : 103)
Query Neighborhood Hits	437	Target Neighborhood Hits	377	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SNTB2_MOUSE
NC score	0.224497 (rank : 118)	θ value	0.0431538 (rank : 150)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	106
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

MAGI1_MOUSE
NC score	0.224093 (rank : 119)	θ value	0.0961366 (rank : 176)
Query Neighborhood Hits	437	Target Neighborhood Hits	403	Shared Neighborhood Hits	158
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

SNTB1_MOUSE
NC score	0.223324 (rank : 120)	θ value	0.00509761 (rank : 110)
Query Neighborhood Hits	437	Target Neighborhood Hits	160	Shared Neighborhood Hits	102
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PA24B_MOUSE
NC score	0.223189 (rank : 121)	θ value	0.0431538 (rank : 148)
Query Neighborhood Hits	437	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

GRIP1_MOUSE
NC score	0.222628 (rank : 122)	θ value	1.06291 (rank : 256)
Query Neighborhood Hits	437	Target Neighborhood Hits	241	Shared Neighborhood Hits	132
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MAGI1_HUMAN
NC score	0.221170 (rank : 123)	θ value	0.125558 (rank : 186)
Query Neighborhood Hits	437	Target Neighborhood Hits	388	Shared Neighborhood Hits	160
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

LNX1_HUMAN
NC score	0.221161 (rank : 124)	θ value	0.0563607 (rank : 156)
Query Neighborhood Hits	437	Target Neighborhood Hits	379	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

NEDD4_MOUSE
NC score	0.220883 (rank : 125)	θ value	0.0736092 (rank : 168)
Query Neighborhood Hits	437	Target Neighborhood Hits	212	Shared Neighborhood Hits	96
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

RASA2_MOUSE
NC score	0.220401 (rank : 126)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	437	Target Neighborhood Hits	159	Shared Neighborhood Hits	71
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RGS3_HUMAN
NC score	0.220285 (rank : 127)	θ value	0.000121331 (rank : 79)
Query Neighborhood Hits	437	Target Neighborhood Hits	1375	Shared Neighborhood Hits	164
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RASA2_HUMAN
NC score	0.219800 (rank : 128)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	437	Target Neighborhood Hits	157	Shared Neighborhood Hits	72
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

P3C2G_HUMAN
NC score	0.219602 (rank : 129)	θ value	4.1701e-05 (rank : 71)
Query Neighborhood Hits	437	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

ZO3_MOUSE
NC score	0.216405 (rank : 130)	θ value	0.000158464 (rank : 83)
Query Neighborhood Hits	437	Target Neighborhood Hits	224	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNTG2_MOUSE
NC score	0.216373 (rank : 131)	θ value	0.279714 (rank : 205)
Query Neighborhood Hits	437	Target Neighborhood Hits	176	Shared Neighborhood Hits	117
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTB1_HUMAN
NC score	0.216263 (rank : 132)	θ value	0.62314 (rank : 237)
Query Neighborhood Hits	437	Target Neighborhood Hits	157	Shared Neighborhood Hits	102
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

DYSF_MOUSE
NC score	0.215630 (rank : 133)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	437	Target Neighborhood Hits	162	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

LIN7A_MOUSE
NC score	0.215110 (rank : 134)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	437	Target Neighborhood Hits	193	Shared Neighborhood Hits	121
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7A_HUMAN
NC score	0.215093 (rank : 135)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	437	Target Neighborhood Hits	193	Shared Neighborhood Hits	121
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

MAGI2_HUMAN
NC score	0.213499 (rank : 136)	θ value	0.813845 (rank : 243)
Query Neighborhood Hits	437	Target Neighborhood Hits	373	Shared Neighborhood Hits	145
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MYOF_HUMAN
NC score	0.212928 (rank : 137)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	437	Target Neighborhood Hits	147	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

MAGI2_MOUSE
NC score	0.212715 (rank : 138)	θ value	1.81305 (rank : 292)
Query Neighborhood Hits	437	Target Neighborhood Hits	370	Shared Neighborhood Hits	144
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

K1849_MOUSE
NC score	0.205113 (rank : 139)	θ value	0.00665767 (rank : 113)
Query Neighborhood Hits	437	Target Neighborhood Hits	335	Shared Neighborhood Hits	121
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

RFIP2_HUMAN
NC score	0.203632 (rank : 140)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	437	Target Neighborhood Hits	97	Shared Neighborhood Hits	65
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

PA24B_HUMAN
NC score	0.203268 (rank : 141)	θ value	0.00390308 (rank : 105)
Query Neighborhood Hits	437	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PICK1_HUMAN
NC score	0.201983 (rank : 142)	θ value	0.0193708 (rank : 131)
Query Neighborhood Hits	437	Target Neighborhood Hits	132	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PA24E_MOUSE
NC score	0.201025 (rank : 143)	θ value	1.81305 (rank : 296)
Query Neighborhood Hits	437	Target Neighborhood Hits	95	Shared Neighborhood Hits	76
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

TAC2N_HUMAN
NC score	0.199928 (rank : 144)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	437	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

PAR6G_MOUSE
NC score	0.199826 (rank : 145)	θ value	0.0736092 (rank : 169)
Query Neighborhood Hits	437	Target Neighborhood Hits	121	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PICK1_MOUSE
NC score	0.199757 (rank : 146)	θ value	0.00869519 (rank : 118)
Query Neighborhood Hits	437	Target Neighborhood Hits	131	Shared Neighborhood Hits	101
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

TAC2N_MOUSE
NC score	0.198608 (rank : 147)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	437	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

PAR6G_HUMAN
NC score	0.197999 (rank : 148)	θ value	0.0252991 (rank : 135)
Query Neighborhood Hits	437	Target Neighborhood Hits	159	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

K1849_HUMAN
NC score	0.196631 (rank : 149)	θ value	0.0252991 (rank : 134)
Query Neighborhood Hits	437	Target Neighborhood Hits	220	Shared Neighborhood Hits	112
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PA24A_MOUSE
NC score	0.193782 (rank : 150)	θ value	0.0961366 (rank : 180)
Query Neighborhood Hits	437	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PAR6A_HUMAN
NC score	0.192385 (rank : 151)	θ value	0.0563607 (rank : 157)
Query Neighborhood Hits	437	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PZRN4_HUMAN
NC score	0.192150 (rank : 152)	θ value	0.00228821 (rank : 100)
Query Neighborhood Hits	437	Target Neighborhood Hits	438	Shared Neighborhood Hits	117
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PAR6A_MOUSE
NC score	0.191933 (rank : 153)	θ value	0.0563607 (rank : 158)
Query Neighborhood Hits	437	Target Neighborhood Hits	115	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

NHRF2_HUMAN
NC score	0.191326 (rank : 154)	θ value	0.0330416 (rank : 141)
Query Neighborhood Hits	437	Target Neighborhood Hits	197	Shared Neighborhood Hits	109
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
NC score	0.191218 (rank : 155)	θ value	0.0113563 (rank : 120)
Query Neighborhood Hits	437	Target Neighborhood Hits	194	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

SNTG1_MOUSE
NC score	0.190513 (rank : 156)	θ value	2.36792 (rank : 316)
Query Neighborhood Hits	437	Target Neighborhood Hits	179	Shared Neighborhood Hits	119
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PZRN3_MOUSE
NC score	0.190464 (rank : 157)	θ value	0.0252991 (rank : 136)
Query Neighborhood Hits	437	Target Neighborhood Hits	447	Shared Neighborhood Hits	124
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ZO3_HUMAN
NC score	0.189859 (rank : 158)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	437	Target Neighborhood Hits	219	Shared Neighborhood Hits	115
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PZRN3_HUMAN
NC score	0.188427 (rank : 159)	θ value	0.0563607 (rank : 159)
Query Neighborhood Hits	437	Target Neighborhood Hits	461	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SNTG1_HUMAN
NC score	0.188286 (rank : 160)	θ value	3.0926 (rank : 328)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ZO2_HUMAN
NC score	0.186191 (rank : 161)	θ value	0.365318 (rank : 214)
Query Neighborhood Hits	437	Target Neighborhood Hits	289	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PA24A_HUMAN
NC score	0.186161 (rank : 162)	θ value	0.0961366 (rank : 179)
Query Neighborhood Hits	437	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24E_HUMAN
NC score	0.184886 (rank : 163)	θ value	1.38821 (rank : 274)
Query Neighborhood Hits	437	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

NHERF_HUMAN
NC score	0.184599 (rank : 164)	θ value	0.62314 (rank : 231)
Query Neighborhood Hits	437	Target Neighborhood Hits	190	Shared Neighborhood Hits	102
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

ZO2_MOUSE
NC score	0.184413 (rank : 165)	θ value	0.279714 (rank : 206)
Query Neighborhood Hits	437	Target Neighborhood Hits	296	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PAR6B_HUMAN
NC score	0.183679 (rank : 166)	θ value	0.125558 (rank : 187)
Query Neighborhood Hits	437	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

NHERF_MOUSE
NC score	0.183388 (rank : 167)	θ value	1.06291 (rank : 261)
Query Neighborhood Hits	437	Target Neighborhood Hits	195	Shared Neighborhood Hits	105
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PAR6B_MOUSE
NC score	0.182224 (rank : 168)	θ value	0.365318 (rank : 211)
Query Neighborhood Hits	437	Target Neighborhood Hits	128	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

ZO1_MOUSE
NC score	0.180852 (rank : 169)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	437	Target Neighborhood Hits	453	Shared Neighborhood Hits	147
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

PDZ11_HUMAN
NC score	0.180630 (rank : 170)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	437	Target Neighborhood Hits	160	Shared Neighborhood Hits	97
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZD1_MOUSE
NC score	0.180329 (rank : 171)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	437	Target Neighborhood Hits	191	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

KPCG_MOUSE
NC score	0.180214 (rank : 172)	θ value	5.62301e-10 (rank : 37)
Query Neighborhood Hits	437	Target Neighborhood Hits	1123	Shared Neighborhood Hits	113
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PDZ11_MOUSE
NC score	0.179679 (rank : 173)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	437	Target Neighborhood Hits	154	Shared Neighborhood Hits	92
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SRRM2_MOUSE
NC score	0.179607 (rank : 174)	θ value	2.36244e-08 (rank : 48)
Query Neighborhood Hits	437	Target Neighborhood Hits	1470	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

KPCG_HUMAN
NC score	0.179361 (rank : 175)	θ value	1.25267e-09 (rank : 41)
Query Neighborhood Hits	437	Target Neighborhood Hits	1126	Shared Neighborhood Hits	113
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

ZO1_HUMAN
NC score	0.178728 (rank : 176)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	437	Target Neighborhood Hits	474	Shared Neighborhood Hits	136
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

OTOF_HUMAN
NC score	0.178038 (rank : 177)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	437	Target Neighborhood Hits	168	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
NC score	0.177759 (rank : 178)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	437	Target Neighborhood Hits	196	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

TX1B3_HUMAN
NC score	0.177436 (rank : 179)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	437	Target Neighborhood Hits	161	Shared Neighborhood Hits	105
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

PDZD1_HUMAN
NC score	0.176724 (rank : 180)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	437	Target Neighborhood Hits	190	Shared Neighborhood Hits	103
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NEB1_HUMAN
NC score	0.174085 (rank : 181)	θ value	0.00665767 (rank : 114)
Query Neighborhood Hits	437	Target Neighborhood Hits	829	Shared Neighborhood Hits	145
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

TX1B3_MOUSE
NC score	0.173525 (rank : 182)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	437	Target Neighborhood Hits	158	Shared Neighborhood Hits	102
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PTN13_HUMAN
NC score	0.172937 (rank : 183)	θ value	1.43324e-05 (rank : 66)
Query Neighborhood Hits	437	Target Neighborhood Hits	471	Shared Neighborhood Hits	146
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

RASA3_MOUSE
NC score	0.172584 (rank : 184)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	437	Target Neighborhood Hits	144	Shared Neighborhood Hits	66
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

SRRM2_HUMAN
NC score	0.170921 (rank : 185)	θ value	0.000158464 (rank : 82)
Query Neighborhood Hits	437	Target Neighborhood Hits	1296	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

KPCA_HUMAN
NC score	0.169489 (rank : 186)	θ value	1.133e-10 (rank : 27)
Query Neighborhood Hits	437	Target Neighborhood Hits	1070	Shared Neighborhood Hits	115
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

AFAD_HUMAN
NC score	0.167743 (rank : 187)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	437	Target Neighborhood Hits	689	Shared Neighborhood Hits	142
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

KPCB_MOUSE
NC score	0.166814 (rank : 188)	θ value	5.62301e-10 (rank : 36)
Query Neighborhood Hits	437	Target Neighborhood Hits	1117	Shared Neighborhood Hits	114
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
NC score	0.165939 (rank : 189)	θ value	3.29651e-10 (rank : 32)
Query Neighborhood Hits	437	Target Neighborhood Hits	1121	Shared Neighborhood Hits	115
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

PTN13_MOUSE
NC score	0.165887 (rank : 190)	θ value	0.000121331 (rank : 78)
Query Neighborhood Hits	437	Target Neighborhood Hits	426	Shared Neighborhood Hits	139
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

KPCA_MOUSE
NC score	0.165344 (rank : 191)	θ value	4.30538e-10 (rank : 34)
Query Neighborhood Hits	437	Target Neighborhood Hits	1067	Shared Neighborhood Hits	115
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

PA24F_MOUSE
NC score	0.164710 (rank : 192)	θ value	0.62314 (rank : 232)
Query Neighborhood Hits	437	Target Neighborhood Hits	93	Shared Neighborhood Hits	66
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

LAP4_HUMAN
NC score	0.162430 (rank : 193)	θ value	0.00509761 (rank : 107)
Query Neighborhood Hits	437	Target Neighborhood Hits	608	Shared Neighborhood Hits	140
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PDZK4_MOUSE
NC score	0.161316 (rank : 194)	θ value	0.21417 (rank : 197)
Query Neighborhood Hits	437	Target Neighborhood Hits	165	Shared Neighborhood Hits	102
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZD3_HUMAN
NC score	0.161089 (rank : 195)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	437	Target Neighborhood Hits	180	Shared Neighborhood Hits	101
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

MPP5_HUMAN
NC score	0.160631 (rank : 196)	θ value	0.0961366 (rank : 177)
Query Neighborhood Hits	437	Target Neighborhood Hits	231	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

LAP4_MOUSE
NC score	0.160497 (rank : 197)	θ value	0.00509761 (rank : 108)
Query Neighborhood Hits	437	Target Neighborhood Hits	590	Shared Neighborhood Hits	142
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MPP5_MOUSE
NC score	0.159922 (rank : 198)	θ value	0.0961366 (rank : 178)
Query Neighborhood Hits	437	Target Neighborhood Hits	226	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

DLG5_HUMAN
NC score	0.159576 (rank : 199)	θ value	0.0193708 (rank : 127)
Query Neighborhood Hits	437	Target Neighborhood Hits	1088	Shared Neighborhood Hits	143
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

MPP4_HUMAN
NC score	0.159558 (rank : 200)	θ value	0.163984 (rank : 190)
Query Neighborhood Hits	437	Target Neighborhood Hits	205	Shared Neighborhood Hits	115
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

SDCB1_MOUSE
NC score	0.157682 (rank : 201)	θ value	0.125558 (rank : 189)
Query Neighborhood Hits	437	Target Neighborhood Hits	144	Shared Neighborhood Hits	94
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

PDZD3_MOUSE
NC score	0.155656 (rank : 202)	θ value	2.36792 (rank : 311)
Query Neighborhood Hits	437	Target Neighborhood Hits	171	Shared Neighborhood Hits	95
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SDCB1_HUMAN
NC score	0.154955 (rank : 203)	θ value	0.125558 (rank : 188)
Query Neighborhood Hits	437	Target Neighborhood Hits	150	Shared Neighborhood Hits	99
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

NEB2_MOUSE
NC score	0.152639 (rank : 204)	θ value	0.0431538 (rank : 147)
Query Neighborhood Hits	437	Target Neighborhood Hits	889	Shared Neighborhood Hits	135
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

APBA1_HUMAN
NC score	0.151768 (rank : 205)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	437	Target Neighborhood Hits	325	Shared Neighborhood Hits	125
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

APBA2_MOUSE
NC score	0.151659 (rank : 206)	θ value	0.00869519 (rank : 116)
Query Neighborhood Hits	437	Target Neighborhood Hits	219	Shared Neighborhood Hits	113
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

NEB2_HUMAN
NC score	0.151160 (rank : 207)	θ value	0.0431538 (rank : 146)
Query Neighborhood Hits	437	Target Neighborhood Hits	883	Shared Neighborhood Hits	132
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

MYRIP_MOUSE
NC score	0.146498 (rank : 208)	θ value	2.36792 (rank : 310)
Query Neighborhood Hits	437	Target Neighborhood Hits	207	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

DVL3_MOUSE
NC score	0.146404 (rank : 209)	θ value	2.36792 (rank : 307)
Query Neighborhood Hits	437	Target Neighborhood Hits	198	Shared Neighborhood Hits	96
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1_HUMAN
NC score	0.144980 (rank : 210)	θ value	0.62314 (rank : 227)
Query Neighborhood Hits	437	Target Neighborhood Hits	158	Shared Neighborhood Hits	96
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL3_HUMAN
NC score	0.144474 (rank : 211)	θ value	2.36792 (rank : 306)
Query Neighborhood Hits	437	Target Neighborhood Hits	194	Shared Neighborhood Hits	91
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

STXB4_HUMAN
NC score	0.144327 (rank : 212)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	437	Target Neighborhood Hits	616	Shared Neighborhood Hits	101
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
NC score	0.143201 (rank : 213)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	437	Target Neighborhood Hits	629	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DVL2_MOUSE
NC score	0.141429 (rank : 214)	θ value	1.81305 (rank : 286)
Query Neighborhood Hits	437	Target Neighborhood Hits	233	Shared Neighborhood Hits	99
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PDZK4_HUMAN
NC score	0.141257 (rank : 215)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	437	Target Neighborhood Hits	165	Shared Neighborhood Hits	94
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

ITSN2_HUMAN
NC score	0.140471 (rank : 216)	θ value	0.0193708 (rank : 129)
Query Neighborhood Hits	437	Target Neighborhood Hits	1173	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

DVL1_MOUSE
NC score	0.140304 (rank : 217)	θ value	0.62314 (rank : 228)
Query Neighborhood Hits	437	Target Neighborhood Hits	146	Shared Neighborhood Hits	87
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL2_HUMAN
NC score	0.139776 (rank : 218)	θ value	2.36792 (rank : 305)
Query Neighborhood Hits	437	Target Neighborhood Hits	223	Shared Neighborhood Hits	100
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

GIPC1_MOUSE
NC score	0.139418 (rank : 219)	θ value	0.0736092 (rank : 166)
Query Neighborhood Hits	437	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

PA24F_HUMAN
NC score	0.139161 (rank : 220)	θ value	0.21417 (rank : 196)
Query Neighborhood Hits	437	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

APBA2_HUMAN
NC score	0.137963 (rank : 221)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	437	Target Neighborhood Hits	220	Shared Neighborhood Hits	111
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

DVL1L_HUMAN
NC score	0.135093 (rank : 222)	θ value	1.38821 (rank : 266)
Query Neighborhood Hits	437	Target Neighborhood Hits	146	Shared Neighborhood Hits	88
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

GIPC1_HUMAN
NC score	0.134694 (rank : 223)	θ value	0.0961366 (rank : 173)
Query Neighborhood Hits	437	Target Neighborhood Hits	91	Shared Neighborhood Hits	68
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

MPP3_MOUSE
NC score	0.134396 (rank : 224)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	437	Target Neighborhood Hits	165	Shared Neighborhood Hits	107
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP3_HUMAN
NC score	0.133413 (rank : 225)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	437	Target Neighborhood Hits	171	Shared Neighborhood Hits	107
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

SRRM1_MOUSE
NC score	0.133340 (rank : 226)	θ value	0.813845 (rank : 249)
Query Neighborhood Hits	437	Target Neighborhood Hits	966	Shared Neighborhood Hits	125
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ITSN2_MOUSE
NC score	0.128129 (rank : 227)	θ value	0.0736092 (rank : 167)
Query Neighborhood Hits	437	Target Neighborhood Hits	1371	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

APXL_HUMAN
NC score	0.127901 (rank : 228)	θ value	0.62314 (rank : 226)
Query Neighborhood Hits	437	Target Neighborhood Hits	553	Shared Neighborhood Hits	105
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

MPP4_MOUSE
NC score	0.127845 (rank : 229)	θ value	3.0926 (rank : 321)
Query Neighborhood Hits	437	Target Neighborhood Hits	188	Shared Neighborhood Hits	101
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

APBA3_HUMAN
NC score	0.126883 (rank : 230)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	437	Target Neighborhood Hits	201	Shared Neighborhood Hits	109
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SRRM1_HUMAN
NC score	0.126294 (rank : 231)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	437	Target Neighborhood Hits	690	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MYRIP_HUMAN
NC score	0.124869 (rank : 232)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	437	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

CPNE3_HUMAN
NC score	0.121999 (rank : 233)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	437	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

NOS1_HUMAN
NC score	0.121756 (rank : 234)	θ value	0.21417 (rank : 195)
Query Neighborhood Hits	437	Target Neighborhood Hits	218	Shared Neighborhood Hits	109
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SDCB2_MOUSE
NC score	0.121742 (rank : 235)	θ value	0.62314 (rank : 234)
Query Neighborhood Hits	437	Target Neighborhood Hits	118	Shared Neighborhood Hits	76
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

CPNE3_MOUSE
NC score	0.121729 (rank : 236)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	437	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

NIPBL_HUMAN
NC score	0.119445 (rank : 237)	θ value	0.00102713 (rank : 93)
Query Neighborhood Hits	437	Target Neighborhood Hits	1311	Shared Neighborhood Hits	138
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SDCB2_HUMAN
NC score	0.119192 (rank : 238)	θ value	0.47712 (rank : 223)
Query Neighborhood Hits	437	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

APBA3_MOUSE
NC score	0.117673 (rank : 239)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	437	Target Neighborhood Hits	174	Shared Neighborhood Hits	102
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

BSN_MOUSE
NC score	0.115964 (rank : 240)	θ value	0.0961366 (rank : 172)
Query Neighborhood Hits	437	Target Neighborhood Hits	2057	Shared Neighborhood Hits	121
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NPBL_MOUSE
NC score	0.114089 (rank : 241)	θ value	0.00869519 (rank : 117)
Query Neighborhood Hits	437	Target Neighborhood Hits	1041	Shared Neighborhood Hits	117
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

EM55_MOUSE
NC score	0.113985 (rank : 242)	θ value	8.99809 (rank : 406)
Query Neighborhood Hits	437	Target Neighborhood Hits	221	Shared Neighborhood Hits	106
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

EM55_HUMAN
NC score	0.113883 (rank : 243)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	437	Target Neighborhood Hits	228	Shared Neighborhood Hits	109
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

ITSN1_MOUSE
NC score	0.111676 (rank : 244)	θ value	0.0330416 (rank : 140)
Query Neighborhood Hits	437	Target Neighborhood Hits	1669	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CPNE5_MOUSE
NC score	0.111627 (rank : 245)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	437	Target Neighborhood Hits	86	Shared Neighborhood Hits	58
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_HUMAN
NC score	0.111511 (rank : 246)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	437	Target Neighborhood Hits	88	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

BSN_HUMAN
NC score	0.111458 (rank : 247)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	437	Target Neighborhood Hits	1537	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GIPC2_HUMAN
NC score	0.110732 (rank : 248)	θ value	1.81305 (rank : 287)
Query Neighborhood Hits	437	Target Neighborhood Hits	93	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

ITSN1_HUMAN
NC score	0.109611 (rank : 249)	θ value	0.0330416 (rank : 139)
Query Neighborhood Hits	437	Target Neighborhood Hits	1757	Shared Neighborhood Hits	146
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NOLC1_HUMAN
NC score	0.109605 (rank : 250)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	437	Target Neighborhood Hits	452	Shared Neighborhood Hits	74
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SMUF1_HUMAN
NC score	0.109525 (rank : 251)	θ value	1.38821 (rank : 276)
Query Neighborhood Hits	437	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

RGS12_HUMAN
NC score	0.108820 (rank : 252)	θ value	0.813845 (rank : 246)
Query Neighborhood Hits	437	Target Neighborhood Hits	333	Shared Neighborhood Hits	104
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SMUF1_MOUSE
NC score	0.108652 (rank : 253)	θ value	1.38821 (rank : 277)
Query Neighborhood Hits	437	Target Neighborhood Hits	142	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SFR11_HUMAN
NC score	0.108547 (rank : 254)	θ value	2.36792 (rank : 314)
Query Neighborhood Hits	437	Target Neighborhood Hits	246	Shared Neighborhood Hits	45
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SMUF2_HUMAN
NC score	0.107696 (rank : 255)	θ value	1.81305 (rank : 298)
Query Neighborhood Hits	437	Target Neighborhood Hits	142	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

BASP_HUMAN
NC score	0.107537 (rank : 256)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	437	Target Neighborhood Hits	321	Shared Neighborhood Hits	60
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CPNE8_HUMAN
NC score	0.107494 (rank : 257)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	437	Target Neighborhood Hits	86	Shared Neighborhood Hits	58
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE2_HUMAN
NC score	0.107235 (rank : 258)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	437	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
NC score	0.107031 (rank : 259)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	437	Target Neighborhood Hits	82	Shared Neighborhood Hits	55
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

SYNP2_MOUSE
NC score	0.104976 (rank : 260)	θ value	3.0926 (rank : 330)
Query Neighborhood Hits	437	Target Neighborhood Hits	252	Shared Neighborhood Hits	96
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

RFIP1_HUMAN
NC score	0.104702 (rank : 261)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	437	Target Neighborhood Hits	236	Shared Neighborhood Hits	71
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

CPNE8_MOUSE
NC score	0.104617 (rank : 262)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	437	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

TGON2_HUMAN
NC score	0.104399 (rank : 263)	θ value	0.00035302 (rank : 88)
Query Neighborhood Hits	437	Target Neighborhood Hits	1037	Shared Neighborhood Hits	118
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CPNE1_MOUSE
NC score	0.103589 (rank : 264)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	437	Target Neighborhood Hits	83	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

NOS1_MOUSE
NC score	0.103250 (rank : 265)	θ value	0.279714 (rank : 203)
Query Neighborhood Hits	437	Target Neighborhood Hits	155	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

GPTC8_HUMAN
NC score	0.102123 (rank : 266)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	437	Target Neighborhood Hits	366	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

TXND2_HUMAN
NC score	0.101997 (rank : 267)	θ value	3.19293e-05 (rank : 69)
Query Neighborhood Hits	437	Target Neighborhood Hits	793	Shared Neighborhood Hits	87
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RPGF6_HUMAN
NC score	0.101745 (rank : 268)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	437	Target Neighborhood Hits	266	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

FA47A_HUMAN
NC score	0.100627 (rank : 269)	θ value	0.0330416 (rank : 138)
Query Neighborhood Hits	437	Target Neighborhood Hits	451	Shared Neighborhood Hits	50
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

IWS1_HUMAN
NC score	0.100320 (rank : 270)	θ value	0.0193708 (rank : 130)
Query Neighborhood Hits	437	Target Neighborhood Hits	1241	Shared Neighborhood Hits	122
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RFIP1_MOUSE
NC score	0.099647 (rank : 271)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	437	Target Neighborhood Hits	152	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TARA_HUMAN
NC score	0.098839 (rank : 272)	θ value	0.0252991 (rank : 137)
Query Neighborhood Hits	437	Target Neighborhood Hits	1626	Shared Neighborhood Hits	131
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SYP2L_HUMAN
NC score	0.097147 (rank : 273)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	437	Target Neighborhood Hits	400	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

GRASP_HUMAN
NC score	0.097078 (rank : 274)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	437	Target Neighborhood Hits	147	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

IWS1_MOUSE
NC score	0.097036 (rank : 275)	θ value	0.00134147 (rank : 96)
Query Neighborhood Hits	437	Target Neighborhood Hits	1258	Shared Neighborhood Hits	119
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ARHGB_HUMAN
NC score	0.096962 (rank : 276)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	437	Target Neighborhood Hits	375	Shared Neighborhood Hits	119
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

CPNE7_HUMAN
NC score	0.094921 (rank : 277)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	437	Target Neighborhood Hits	92	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SNUT3_HUMAN
NC score	0.094616 (rank : 278)	θ value	0.163984 (rank : 191)
Query Neighborhood Hits	437	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WVK2, Q15410	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3 (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (Nucleic acid-binding protein RY-1).

GIPC2_MOUSE
NC score	0.093926 (rank : 279)	θ value	1.81305 (rank : 288)
Query Neighborhood Hits	437	Target Neighborhood Hits	71	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

MPP6_MOUSE
NC score	0.093024 (rank : 280)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	437	Target Neighborhood Hits	187	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

GRASP_MOUSE
NC score	0.092579 (rank : 281)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	437	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PDLI2_HUMAN
NC score	0.091741 (rank : 282)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	437	Target Neighborhood Hits	245	Shared Neighborhood Hits	79
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

MPP6_HUMAN
NC score	0.091635 (rank : 283)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	437	Target Neighborhood Hits	180	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

SNUT3_MOUSE
NC score	0.090635 (rank : 284)	θ value	0.163984 (rank : 192)
Query Neighborhood Hits	437	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K194, Q8BRA8, Q9CSV0	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3.

PSCBP_MOUSE
NC score	0.090340 (rank : 285)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	437	Target Neighborhood Hits	118	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

MPP2_MOUSE
NC score	0.090269 (rank : 286)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	437	Target Neighborhood Hits	189	Shared Neighborhood Hits	84
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

RHPN1_MOUSE
NC score	0.089973 (rank : 287)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	437	Target Neighborhood Hits	154	Shared Neighborhood Hits	83
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

MPP2_HUMAN
NC score	0.089889 (rank : 288)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	437	Target Neighborhood Hits	173	Shared Neighborhood Hits	77
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

GIPC3_MOUSE
NC score	0.088969 (rank : 289)	θ value	0.21417 (rank : 194)
Query Neighborhood Hits	437	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

ARHGC_MOUSE
NC score	0.088321 (rank : 290)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	437	Target Neighborhood Hits	344	Shared Neighborhood Hits	110
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_HUMAN
NC score	0.088108 (rank : 291)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	437	Target Neighborhood Hits	351	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SFRIP_HUMAN
NC score	0.087708 (rank : 292)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	437	Target Neighborhood Hits	530	Shared Neighborhood Hits	100
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

GIPC3_HUMAN
NC score	0.087403 (rank : 293)	θ value	0.47712 (rank : 217)
Query Neighborhood Hits	437	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

SFR12_MOUSE
NC score	0.086074 (rank : 294)	θ value	0.813845 (rank : 247)
Query Neighborhood Hits	437	Target Neighborhood Hits	486	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

CPNE1_HUMAN
NC score	0.085435 (rank : 295)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	437	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

RPGF2_HUMAN
NC score	0.085298 (rank : 296)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	437	Target Neighborhood Hits	242	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

WWC1_MOUSE
NC score	0.085221 (rank : 297)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	44
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

RHPN1_HUMAN
NC score	0.084580 (rank : 298)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	437	Target Neighborhood Hits	158	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

BASP_MOUSE
NC score	0.084147 (rank : 299)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	437	Target Neighborhood Hits	260	Shared Neighborhood Hits	48
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MELPH_MOUSE
NC score	0.083302 (rank : 300)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	437	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

PDLI2_MOUSE
NC score	0.083204 (rank : 301)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	437	Target Neighborhood Hits	220	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

TXND2_MOUSE
NC score	0.083127 (rank : 302)	θ value	0.813845 (rank : 250)
Query Neighborhood Hits	437	Target Neighborhood Hits	828	Shared Neighborhood Hits	91
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TCOF_MOUSE
NC score	0.082201 (rank : 303)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	437	Target Neighborhood Hits	471	Shared Neighborhood Hits	76
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

MDC1_HUMAN
NC score	0.082069 (rank : 304)	θ value	0.62314 (rank : 230)
Query Neighborhood Hits	437	Target Neighborhood Hits	1446	Shared Neighborhood Hits	114
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ENL_HUMAN
NC score	0.081820 (rank : 305)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	437	Target Neighborhood Hits	305	Shared Neighborhood Hits	57
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

MELPH_HUMAN
NC score	0.081528 (rank : 306)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	437	Target Neighborhood Hits	145	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

PLCD1_HUMAN
NC score	0.081382 (rank : 307)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	437	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PDZD8_HUMAN
NC score	0.080970 (rank : 308)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	437	Target Neighborhood Hits	185	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

TARA_MOUSE
NC score	0.080491 (rank : 309)	θ value	0.0148317 (rank : 126)
Query Neighborhood Hits	437	Target Neighborhood Hits	1133	Shared Neighborhood Hits	94
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CN155_HUMAN
NC score	0.080398 (rank : 310)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	437	Target Neighborhood Hits	385	Shared Neighborhood Hits	67
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

MUC7_HUMAN
NC score	0.079160 (rank : 311)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	437	Target Neighborhood Hits	538	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

SFRS4_HUMAN
NC score	0.078668 (rank : 312)	θ value	0.62314 (rank : 235)
Query Neighborhood Hits	437	Target Neighborhood Hits	384	Shared Neighborhood Hits	54
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

RSRC1_HUMAN
NC score	0.076868 (rank : 313)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	437	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

PSCBP_HUMAN
NC score	0.076661 (rank : 314)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	437	Target Neighborhood Hits	123	Shared Neighborhood Hits	74
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

CPNE6_HUMAN
NC score	0.076476 (rank : 315)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	437	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

SHAN2_HUMAN
NC score	0.076132 (rank : 316)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	437	Target Neighborhood Hits	346	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

CPNE6_MOUSE
NC score	0.075970 (rank : 317)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	437	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

TCOF_HUMAN
NC score	0.074178 (rank : 318)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	437	Target Neighborhood Hits	543	Shared Neighborhood Hits	77
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

SFR12_HUMAN
NC score	0.073844 (rank : 319)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	437	Target Neighborhood Hits	553	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

ACINU_HUMAN
NC score	0.073652 (rank : 320)	θ value	1.06291 (rank : 251)
Query Neighborhood Hits	437	Target Neighborhood Hits	828	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SYNP2_HUMAN
NC score	0.073621 (rank : 321)	θ value	3.0926 (rank : 329)
Query Neighborhood Hits	437	Target Neighborhood Hits	323	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SON_MOUSE
NC score	0.073193 (rank : 322)	θ value	0.163984 (rank : 193)
Query Neighborhood Hits	437	Target Neighborhood Hits	957	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

PRG4_HUMAN
NC score	0.073030 (rank : 323)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	437	Target Neighborhood Hits	764	Shared Neighborhood Hits	78
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SHAN2_MOUSE
NC score	0.072931 (rank : 324)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	437	Target Neighborhood Hits	446	Shared Neighborhood Hits	110
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

NFH_MOUSE
NC score	0.072891 (rank : 325)	θ value	3.41135e-07 (rank : 54)
Query Neighborhood Hits	437	Target Neighborhood Hits	2247	Shared Neighborhood Hits	165
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SFRS4_MOUSE
NC score	0.072529 (rank : 326)	θ value	2.36792 (rank : 315)
Query Neighborhood Hits	437	Target Neighborhood Hits	406	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

GP143_HUMAN
NC score	0.072389 (rank : 327)	θ value	0.47712 (rank : 218)
Query Neighborhood Hits	437	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P51810	Gene names	GPR143, OA1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein).

ALO17_HUMAN
NC score	0.072227 (rank : 328)	θ value	0.0563607 (rank : 151)
Query Neighborhood Hits	437	Target Neighborhood Hits	317	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

TCAL3_MOUSE
NC score	0.072212 (rank : 329)	θ value	3.0926 (rank : 331)
Query Neighborhood Hits	437	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

PRG4_MOUSE
NC score	0.072127 (rank : 330)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	437	Target Neighborhood Hits	624	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RBBP6_MOUSE
NC score	0.072122 (rank : 331)	θ value	4.03905 (rank : 342)
Query Neighborhood Hits	437	Target Neighborhood Hits	1014	Shared Neighborhood Hits	101
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

PK3CG_HUMAN
NC score	0.071796 (rank : 332)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	437	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.071621 (rank : 333)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	437	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

RBBP6_HUMAN
NC score	0.071576 (rank : 334)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	437	Target Neighborhood Hits	1135	Shared Neighborhood Hits	120
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

MAP4_MOUSE
NC score	0.070899 (rank : 335)	θ value	1.06291 (rank : 258)
Query Neighborhood Hits	437	Target Neighborhood Hits	409	Shared Neighborhood Hits	48
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

LAD1_MOUSE
NC score	0.070491 (rank : 336)	θ value	0.279714 (rank : 201)
Query Neighborhood Hits	437	Target Neighborhood Hits	391	Shared Neighborhood Hits	51
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MINT_HUMAN
NC score	0.070247 (rank : 337)	θ value	0.279714 (rank : 202)
Query Neighborhood Hits	437	Target Neighborhood Hits	1291	Shared Neighborhood Hits	119
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PK3CA_HUMAN
NC score	0.070069 (rank : 338)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	437	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PRP1_HUMAN
NC score	0.070068 (rank : 339)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	437	Target Neighborhood Hits	385	Shared Neighborhood Hits	49
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PK3CA_MOUSE
NC score	0.069961 (rank : 340)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	437	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

CPNE4_HUMAN
NC score	0.069050 (rank : 341)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	437	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

SLC2B_HUMAN
NC score	0.068453 (rank : 342)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	437	Target Neighborhood Hits	214	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

MARCS_HUMAN
NC score	0.068364 (rank : 343)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	437	Target Neighborhood Hits	204	Shared Neighborhood Hits	40
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

NACAM_MOUSE
NC score	0.068206 (rank : 344)	θ value	1.38821 (rank : 270)
Query Neighborhood Hits	437	Target Neighborhood Hits	1866	Shared Neighborhood Hits	119
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

KGUA_MOUSE
NC score	0.067698 (rank : 345)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	437	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

CPNE4_MOUSE
NC score	0.067491 (rank : 346)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	437	Target Neighborhood Hits	67	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

ZC313_HUMAN
NC score	0.067488 (rank : 347)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	437	Target Neighborhood Hits	772	Shared Neighborhood Hits	94
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CJ078_MOUSE
NC score	0.067455 (rank : 348)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	437	Target Neighborhood Hits	559	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

KGUA_HUMAN
NC score	0.067368 (rank : 349)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	437	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

TCAL5_HUMAN
NC score	0.067054 (rank : 350)	θ value	0.00175202 (rank : 98)
Query Neighborhood Hits	437	Target Neighborhood Hits	806	Shared Neighborhood Hits	71
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

PK3CD_HUMAN
NC score	0.066688 (rank : 351)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	437	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
NC score	0.066552 (rank : 352)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	437	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

SHAN1_HUMAN
NC score	0.066493 (rank : 353)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	437	Target Neighborhood Hits	1041	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TCAL5_MOUSE
NC score	0.066222 (rank : 354)	θ value	1.81305 (rank : 300)
Query Neighborhood Hits	437	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CCT4, Q497R6	Gene names	Tceal5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

SYP2L_MOUSE
NC score	0.066205 (rank : 355)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	437	Target Neighborhood Hits	289	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PK3CB_MOUSE
NC score	0.065978 (rank : 356)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	437	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_HUMAN
NC score	0.065932 (rank : 357)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	437	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

RP1L1_HUMAN
NC score	0.065030 (rank : 358)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	437	Target Neighborhood Hits	1072	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CJ012_HUMAN
NC score	0.064950 (rank : 359)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	437	Target Neighborhood Hits	467	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

DSPP_HUMAN
NC score	0.064922 (rank : 360)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	437	Target Neighborhood Hits	645	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

WWC1_HUMAN
NC score	0.064838 (rank : 361)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	437	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

SFR17_HUMAN
NC score	0.064796 (rank : 362)	θ value	1.81305 (rank : 297)
Query Neighborhood Hits	437	Target Neighborhood Hits	325	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

MAP1B_HUMAN
NC score	0.064735 (rank : 363)	θ value	2.36792 (rank : 308)
Query Neighborhood Hits	437	Target Neighborhood Hits	903	Shared Neighborhood Hits	89
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

PRB4S_HUMAN
NC score	0.064046 (rank : 364)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	437	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

IBRD1_HUMAN
NC score	0.063927 (rank : 365)	θ value	0.365318 (rank : 208)
Query Neighborhood Hits	437	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

PRR12_HUMAN
NC score	0.063551 (rank : 366)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	437	Target Neighborhood Hits	460	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

MINT_MOUSE
NC score	0.063330 (rank : 367)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	437	Target Neighborhood Hits	1514	Shared Neighborhood Hits	131
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NEUM_MOUSE
NC score	0.062802 (rank : 368)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	437	Target Neighborhood Hits	149	Shared Neighborhood Hits	34
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

PK3C3_HUMAN
NC score	0.062390 (rank : 369)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	437	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
NC score	0.062176 (rank : 370)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	437	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

AFF1_HUMAN
NC score	0.062015 (rank : 371)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	437	Target Neighborhood Hits	506	Shared Neighborhood Hits	74
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CCD55_MOUSE
NC score	0.061757 (rank : 372)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	437	Target Neighborhood Hits	519	Shared Neighborhood Hits	80
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

DSPP_MOUSE
NC score	0.061685 (rank : 373)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	437	Target Neighborhood Hits	491	Shared Neighborhood Hits	57
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PI4KA_HUMAN
NC score	0.061669 (rank : 374)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	437	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

SET1A_HUMAN
NC score	0.061657 (rank : 375)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	437	Target Neighborhood Hits	690	Shared Neighborhood Hits	80
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SON_HUMAN
NC score	0.061475 (rank : 376)	θ value	0.0563607 (rank : 161)
Query Neighborhood Hits	437	Target Neighborhood Hits	1568	Shared Neighborhood Hits	100
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

GNAS3_HUMAN
NC score	0.061388 (rank : 377)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	437	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

MAP4_HUMAN
NC score	0.061128 (rank : 378)	θ value	2.36792 (rank : 309)
Query Neighborhood Hits	437	Target Neighborhood Hits	428	Shared Neighborhood Hits	47
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MDC1_MOUSE
NC score	0.060986 (rank : 379)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	437	Target Neighborhood Hits	998	Shared Neighborhood Hits	87
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

KI67_HUMAN
NC score	0.060969 (rank : 380)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	437	Target Neighborhood Hits	581	Shared Neighborhood Hits	80
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

SFRS8_HUMAN
NC score	0.060895 (rank : 381)	θ value	3.0926 (rank : 327)
Query Neighborhood Hits	437	Target Neighborhood Hits	166	Shared Neighborhood Hits	35
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

MBB1A_HUMAN
NC score	0.060856 (rank : 382)	θ value	1.06291 (rank : 260)
Query Neighborhood Hits	437	Target Neighborhood Hits	665	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

LAD1_HUMAN
NC score	0.060332 (rank : 383)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	437	Target Neighborhood Hits	441	Shared Neighborhood Hits	65
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

PRRT3_HUMAN
NC score	0.060224 (rank : 384)	θ value	0.279714 (rank : 204)
Query Neighborhood Hits	437	Target Neighborhood Hits	998	Shared Neighborhood Hits	70
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

LRRC7_HUMAN
NC score	0.058549 (rank : 385)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	437	Target Neighborhood Hits	423	Shared Neighborhood Hits	88
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PI4KB_HUMAN
NC score	0.058423 (rank : 386)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	437	Target Neighborhood Hits	79	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

LAP2_HUMAN
NC score	0.058413 (rank : 387)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	437	Target Neighborhood Hits	499	Shared Neighborhood Hits	95
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LRRC7_MOUSE
NC score	0.057959 (rank : 388)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	437	Target Neighborhood Hits	416	Shared Neighborhood Hits	89
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MARCS_MOUSE
NC score	0.057772 (rank : 389)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	437	Target Neighborhood Hits	227	Shared Neighborhood Hits	43
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

LDB3_MOUSE
NC score	0.057738 (rank : 390)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	437	Target Neighborhood Hits	510	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

ZRAB2_HUMAN
NC score	0.057487 (rank : 391)	θ value	5.27518 (rank : 372)
Query Neighborhood Hits	437	Target Neighborhood Hits	120	Shared Neighborhood Hits	27
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

RGS3_MOUSE
NC score	0.057379 (rank : 392)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	437	Target Neighborhood Hits	1621	Shared Neighborhood Hits	125
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RPGR1_MOUSE
NC score	0.057006 (rank : 393)	θ value	0.0431538 (rank : 149)
Query Neighborhood Hits	437	Target Neighborhood Hits	713	Shared Neighborhood Hits	62
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

VGLL4_MOUSE
NC score	0.056926 (rank : 394)	θ value	0.0961366 (rank : 183)
Query Neighborhood Hits	437	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q80V24	Gene names	Vgll4
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 4 (Vgl-4).

TRDN_HUMAN
NC score	0.056916 (rank : 395)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	437	Target Neighborhood Hits	542	Shared Neighborhood Hits	57
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

CS016_HUMAN
NC score	0.055870 (rank : 396)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	437	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

LDB3_HUMAN
NC score	0.055844 (rank : 397)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	437	Target Neighborhood Hits	497	Shared Neighborhood Hits	89
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

TCAL6_HUMAN
NC score	0.055763 (rank : 398)	θ value	1.81305 (rank : 301)
Query Neighborhood Hits	437	Target Neighborhood Hits	122	Shared Neighborhood Hits	23
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

CABIN_HUMAN
NC score	0.055692 (rank : 399)	θ value	2.36792 (rank : 304)
Query Neighborhood Hits	437	Target Neighborhood Hits	490	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

TP53B_MOUSE
NC score	0.055664 (rank : 400)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	437	Target Neighborhood Hits	644	Shared Neighborhood Hits	65
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PDLI4_HUMAN
NC score	0.055616 (rank : 401)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	437	Target Neighborhood Hits	245	Shared Neighborhood Hits	77
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

VCXC_HUMAN
NC score	0.055422 (rank : 402)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	437	Target Neighborhood Hits	139	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

BAT2_HUMAN
NC score	0.055418 (rank : 403)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	437	Target Neighborhood Hits	931	Shared Neighborhood Hits	94
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

T2FA_HUMAN
NC score	0.055354 (rank : 404)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	437	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

HIRP3_HUMAN
NC score	0.055340 (rank : 405)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	437	Target Neighborhood Hits	323	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

BAG3_HUMAN
NC score	0.055238 (rank : 406)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	437	Target Neighborhood Hits	314	Shared Neighborhood Hits	50
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

PDLI1_MOUSE
NC score	0.055191 (rank : 407)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	437	Target Neighborhood Hits	213	Shared Neighborhood Hits	72
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

NEUM_HUMAN
NC score	0.055169 (rank : 408)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	437	Target Neighborhood Hits	132	Shared Neighborhood Hits	32
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

PRP2_MOUSE
NC score	0.055155 (rank : 409)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	437	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRAX_MOUSE
NC score	0.055109 (rank : 410)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	437	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

VCX3_HUMAN
NC score	0.055069 (rank : 411)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	437	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

PI4KB_MOUSE
NC score	0.054894 (rank : 412)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	437	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

AFF4_HUMAN
NC score	0.054797 (rank : 413)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	437	Target Neighborhood Hits	611	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

PLCD1_MOUSE
NC score	0.054758 (rank : 414)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	437	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

TCAL3_HUMAN
NC score	0.054710 (rank : 415)	θ value	0.47712 (rank : 225)
Query Neighborhood Hits	437	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

PDLI4_MOUSE
NC score	0.054631 (rank : 416)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	437	Target Neighborhood Hits	233	Shared Neighborhood Hits	71
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

GSCR1_HUMAN
NC score	0.054392 (rank : 417)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	437	Target Neighborhood Hits	674	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PDLI3_HUMAN
NC score	0.054344 (rank : 418)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	437	Target Neighborhood Hits	199	Shared Neighborhood Hits	68
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

YLPM1_HUMAN
NC score	0.054197 (rank : 419)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	437	Target Neighborhood Hits	670	Shared Neighborhood Hits	74
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

WWP1_HUMAN
NC score	0.054137 (rank : 420)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	437	Target Neighborhood Hits	262	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

PRAX_HUMAN
NC score	0.053921 (rank : 421)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	437	Target Neighborhood Hits	215	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

DMP1_MOUSE
NC score	0.053868 (rank : 422)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	437	Target Neighborhood Hits	498	Shared Neighborhood Hits	65
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

ACINU_MOUSE
NC score	0.053794 (rank : 423)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	437	Target Neighborhood Hits	712	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

LAP2_MOUSE
NC score	0.053594 (rank : 424)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	437	Target Neighborhood Hits	482	Shared Neighborhood Hits	88
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

YTDC1_HUMAN
NC score	0.053564 (rank : 425)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	437	Target Neighborhood Hits	458	Shared Neighborhood Hits	71
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

WASIP_HUMAN
NC score	0.053484 (rank : 426)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	437	Target Neighborhood Hits	458	Shared Neighborhood Hits	46
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TGON1_MOUSE
NC score	0.053234 (rank : 427)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	437	Target Neighborhood Hits	243	Shared Neighborhood Hits	43
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

GRP3_HUMAN
NC score	0.053208 (rank : 428)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	437	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

DEK_MOUSE
NC score	0.053190 (rank : 429)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	437	Target Neighborhood Hits	280	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

TP53B_HUMAN
NC score	0.052779 (rank : 430)	θ value	0.365318 (rank : 212)
Query Neighborhood Hits	437	Target Neighborhood Hits	413	Shared Neighborhood Hits	49
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PTN4_HUMAN
NC score	0.052773 (rank : 431)	θ value	0.62314 (rank : 233)
Query Neighborhood Hits	437	Target Neighborhood Hits	303	Shared Neighborhood Hits	85
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PA24C_HUMAN
NC score	0.052504 (rank : 432)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	437	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UP65, O75457, Q9UG68	Gene names	PLA2G4C
Domain Architecture
Description	Cytosolic phospholipase A2 gamma precursor (EC 3.1.1.4) (cPLA2-gamma) (Phospholipase A2 group IVC).

RSRC1_MOUSE
NC score	0.052310 (rank : 433)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	437	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

TMAP1_HUMAN
NC score	0.052262 (rank : 434)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	437	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

GNAS3_MOUSE
NC score	0.052161 (rank : 435)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	437	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

VCX1_HUMAN
NC score	0.052116 (rank : 436)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	437	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

SELPL_MOUSE
NC score	0.051972 (rank : 437)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	437	Target Neighborhood Hits	588	Shared Neighborhood Hits	59
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

PDLI1_HUMAN
NC score	0.051892 (rank : 438)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	437	Target Neighborhood Hits	242	Shared Neighborhood Hits	63
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

DEK_HUMAN
NC score	0.051475 (rank : 439)	θ value	1.38821 (rank : 264)
Query Neighborhood Hits	437	Target Neighborhood Hits	199	Shared Neighborhood Hits	27
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

RAPH1_HUMAN
NC score	0.051397 (rank : 440)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	437	Target Neighborhood Hits	593	Shared Neighborhood Hits	63
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CYLC2_HUMAN
NC score	0.051309 (rank : 441)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	437	Target Neighborhood Hits	223	Shared Neighborhood Hits	32
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

THOC2_HUMAN
NC score	0.051245 (rank : 442)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	437	Target Neighborhood Hits	337	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

BAG3_MOUSE
NC score	0.051080 (rank : 443)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	437	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MAP1B_MOUSE
NC score	0.050871 (rank : 444)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	437	Target Neighborhood Hits	977	Shared Neighborhood Hits	85
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PDLI5_HUMAN
NC score	0.050742 (rank : 445)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	437	Target Neighborhood Hits	322	Shared Neighborhood Hits	88
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDZD6_HUMAN
NC score	0.050637 (rank : 446)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	437	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

MAST4_HUMAN
NC score	0.050509 (rank : 447)	θ value	1.06291 (rank : 259)
Query Neighborhood Hits	437	Target Neighborhood Hits	1804	Shared Neighborhood Hits	166
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NUCKS_HUMAN
NC score	0.050324 (rank : 448)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	437	Target Neighborhood Hits	143	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

AFF4_MOUSE
NC score	0.050243 (rank : 449)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	437	Target Neighborhood Hits	581	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

PININ_HUMAN
NC score	0.050101 (rank : 450)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	437	Target Neighborhood Hits	753	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

TRIPC_HUMAN
NC score	0.050010 (rank : 451)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	437	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ZAR1_MOUSE
NC score	0.049921 (rank : 452)	θ value	1.38821 (rank : 282)
Query Neighborhood Hits	437	Target Neighborhood Hits	254	Shared Neighborhood Hits	22
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

VGLL4_HUMAN
NC score	0.049477 (rank : 453)	θ value	0.365318 (rank : 213)
Query Neighborhood Hits	437	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q14135, Q7L5V0, Q9BQ78	Gene names	VGLL4, KIAA0121
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 4 (Vgl-4).

TAU_MOUSE
NC score	0.049243 (rank : 454)	θ value	4.03905 (rank : 349)
Query Neighborhood Hits	437	Target Neighborhood Hits	502	Shared Neighborhood Hits	46
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

NKTR_HUMAN
NC score	0.048746 (rank : 455)	θ value	0.813845 (rank : 245)
Query Neighborhood Hits	437	Target Neighborhood Hits	658	Shared Neighborhood Hits	84
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

MUC1_HUMAN
NC score	0.048347 (rank : 456)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	437	Target Neighborhood Hits	975	Shared Neighborhood Hits	67
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MYCB2_HUMAN
NC score	0.047172 (rank : 457)	θ value	0.47712 (rank : 219)
Query Neighborhood Hits	437	Target Neighborhood Hits	390	Shared Neighborhood Hits	50
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

CNKR2_MOUSE
NC score	0.046831 (rank : 458)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	437	Target Neighborhood Hits	197	Shared Neighborhood Hits	52
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.046719 (rank : 459)	θ value	5.27518 (rank : 355)
Query Neighborhood Hits	437	Target Neighborhood Hits	197	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CROP_HUMAN
NC score	0.045132 (rank : 460)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	437	Target Neighborhood Hits	402	Shared Neighborhood Hits	41
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

NCOR1_MOUSE
NC score	0.045087 (rank : 461)	θ value	0.813845 (rank : 244)
Query Neighborhood Hits	437	Target Neighborhood Hits	521	Shared Neighborhood Hits	78
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

MYCB2_MOUSE
NC score	0.044446 (rank : 462)	θ value	3.0926 (rank : 322)
Query Neighborhood Hits	437	Target Neighborhood Hits	307	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

SVIL_MOUSE
NC score	0.044215 (rank : 463)	θ value	1.06291 (rank : 262)
Query Neighborhood Hits	437	Target Neighborhood Hits	439	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

AL2S4_MOUSE
NC score	0.043994 (rank : 464)	θ value	0.813845 (rank : 239)
Query Neighborhood Hits	437	Target Neighborhood Hits	193	Shared Neighborhood Hits	27
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

ATX2L_HUMAN
NC score	0.043579 (rank : 465)	θ value	2.36792 (rank : 303)
Query Neighborhood Hits	437	Target Neighborhood Hits	443	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CROP_MOUSE
NC score	0.043062 (rank : 466)	θ value	1.81305 (rank : 284)
Query Neighborhood Hits	437	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CCNL1_MOUSE
NC score	0.039830 (rank : 467)	θ value	1.06291 (rank : 253)
Query Neighborhood Hits	437	Target Neighborhood Hits	71	Shared Neighborhood Hits	22
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

AIM1_HUMAN
NC score	0.039777 (rank : 468)	θ value	0.813845 (rank : 238)
Query Neighborhood Hits	437	Target Neighborhood Hits	247	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

MAST1_HUMAN
NC score	0.038999 (rank : 469)	θ value	1.81305 (rank : 293)
Query Neighborhood Hits	437	Target Neighborhood Hits	1146	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

RAI1_HUMAN
NC score	0.038866 (rank : 470)	θ value	1.38821 (rank : 275)
Query Neighborhood Hits	437	Target Neighborhood Hits	360	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CCNL1_HUMAN
NC score	0.038203 (rank : 471)	θ value	1.06291 (rank : 252)
Query Neighborhood Hits	437	Target Neighborhood Hits	79	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

MAST1_MOUSE
NC score	0.037796 (rank : 472)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	437	Target Neighborhood Hits	1123	Shared Neighborhood Hits	111
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

JARD2_MOUSE
NC score	0.037175 (rank : 473)	θ value	0.0961366 (rank : 174)
Query Neighborhood Hits	437	Target Neighborhood Hits	169	Shared Neighborhood Hits	28
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

MAST2_HUMAN
NC score	0.037118 (rank : 474)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	437	Target Neighborhood Hits	1189	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

KCD18_HUMAN
NC score	0.036879 (rank : 475)	θ value	0.0961366 (rank : 175)
Query Neighborhood Hits	437	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

MAST2_MOUSE
NC score	0.036730 (rank : 476)	θ value	1.81305 (rank : 294)
Query Neighborhood Hits	437	Target Neighborhood Hits	1110	Shared Neighborhood Hits	111
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SFRS6_HUMAN
NC score	0.036727 (rank : 477)	θ value	3.0926 (rank : 326)
Query Neighborhood Hits	437	Target Neighborhood Hits	247	Shared Neighborhood Hits	33
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

RBBP5_HUMAN
NC score	0.036301 (rank : 478)	θ value	0.0193708 (rank : 132)
Query Neighborhood Hits	437	Target Neighborhood Hits	372	Shared Neighborhood Hits	17
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

MO4L2_HUMAN
NC score	0.036281 (rank : 479)	θ value	1.81305 (rank : 295)
Query Neighborhood Hits	437	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

AHTF1_MOUSE
NC score	0.036280 (rank : 480)	θ value	5.27518 (rank : 351)
Query Neighborhood Hits	437	Target Neighborhood Hits	176	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

RPTN_MOUSE
NC score	0.036276 (rank : 481)	θ value	4.03905 (rank : 343)
Query Neighborhood Hits	437	Target Neighborhood Hits	650	Shared Neighborhood Hits	72
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

CXCC1_MOUSE
NC score	0.035769 (rank : 482)	θ value	1.06291 (rank : 254)
Query Neighborhood Hits	437	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

TTF2_MOUSE
NC score	0.035407 (rank : 483)	θ value	1.38821 (rank : 281)
Query Neighborhood Hits	437	Target Neighborhood Hits	364	Shared Neighborhood Hits	61
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ARI2_MOUSE
NC score	0.034733 (rank : 484)	θ value	0.0563607 (rank : 153)
Query Neighborhood Hits	437	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI2_HUMAN
NC score	0.034620 (rank : 485)	θ value	0.0563607 (rank : 152)
Query Neighborhood Hits	437	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

SETD8_MOUSE
NC score	0.034430 (rank : 486)	θ value	0.21417 (rank : 198)
Query Neighborhood Hits	437	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

ANK2_HUMAN
NC score	0.034027 (rank : 487)	θ value	0.47712 (rank : 215)
Query Neighborhood Hits	437	Target Neighborhood Hits	1615	Shared Neighborhood Hits	126
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR11_HUMAN
NC score	0.033154 (rank : 488)	θ value	1.81305 (rank : 283)
Query Neighborhood Hits	437	Target Neighborhood Hits	1289	Shared Neighborhood Hits	105
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

E41L2_MOUSE
NC score	0.032607 (rank : 489)	θ value	0.0736092 (rank : 165)
Query Neighborhood Hits	437	Target Neighborhood Hits	459	Shared Neighborhood Hits	49
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

SRBS1_MOUSE
NC score	0.032383 (rank : 490)	θ value	1.38821 (rank : 278)
Query Neighborhood Hits	437	Target Neighborhood Hits	409	Shared Neighborhood Hits	37
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

MO4L1_HUMAN
NC score	0.032374 (rank : 491)	θ value	0.365318 (rank : 209)
Query Neighborhood Hits	437	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MO4L1_MOUSE
NC score	0.032360 (rank : 492)	θ value	0.365318 (rank : 210)
Query Neighborhood Hits	437	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

UBP31_HUMAN
NC score	0.031751 (rank : 493)	θ value	6.88961 (rank : 393)
Query Neighborhood Hits	437	Target Neighborhood Hits	293	Shared Neighborhood Hits	51
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

SFRS5_MOUSE
NC score	0.031399 (rank : 494)	θ value	0.62314 (rank : 236)
Query Neighborhood Hits	437	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	O35326	Gene names	Sfrs5, Hrs
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

RTN4_HUMAN
NC score	0.030487 (rank : 495)	θ value	4.03905 (rank : 344)
Query Neighborhood Hits	437	Target Neighborhood Hits	357	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CUTL1_MOUSE
NC score	0.030441 (rank : 496)	θ value	0.0431538 (rank : 142)
Query Neighborhood Hits	437	Target Neighborhood Hits	1620	Shared Neighborhood Hits	81
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ANLN_MOUSE
NC score	0.030170 (rank : 497)	θ value	0.813845 (rank : 240)
Query Neighborhood Hits	437	Target Neighborhood Hits	297	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

SPEG_MOUSE
NC score	0.029657 (rank : 498)	θ value	1.81305 (rank : 299)
Query Neighborhood Hits	437	Target Neighborhood Hits	1959	Shared Neighborhood Hits	113
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

VRK3_HUMAN
NC score	0.029521 (rank : 499)	θ value	0.0563607 (rank : 162)
Query Neighborhood Hits	437	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

SFRS5_HUMAN
NC score	0.029249 (rank : 500)	θ value	0.813845 (rank : 248)
Query Neighborhood Hits	437	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	Q13243, O14797, Q16662	Gene names	SFRS5, HRS, SRP40
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

NGEF_MOUSE
NC score	0.029236 (rank : 501)	θ value	0.47712 (rank : 221)
Query Neighborhood Hits	437	Target Neighborhood Hits	228	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PRP4B_MOUSE
NC score	0.028747 (rank : 502)	θ value	2.36792 (rank : 313)
Query Neighborhood Hits	437	Target Neighborhood Hits	1040	Shared Neighborhood Hits	70
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

NALP5_MOUSE
NC score	0.028474 (rank : 503)	θ value	0.47712 (rank : 220)
Query Neighborhood Hits	437	Target Neighborhood Hits	560	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

CHD9_MOUSE
NC score	0.028138 (rank : 504)	θ value	0.0736092 (rank : 163)
Query Neighborhood Hits	437	Target Neighborhood Hits	427	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CUTL1_HUMAN
NC score	0.028098 (rank : 505)	θ value	0.0736092 (rank : 164)
Query Neighborhood Hits	437	Target Neighborhood Hits	1574	Shared Neighborhood Hits	80
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DOCK4_HUMAN
NC score	0.027823 (rank : 506)	θ value	0.813845 (rank : 242)
Query Neighborhood Hits	437	Target Neighborhood Hits	237	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

SFRS7_HUMAN
NC score	0.027587 (rank : 507)	θ value	4.03905 (rank : 347)
Query Neighborhood Hits	437	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q16629	Gene names	SFRS7
Domain Architecture
Description	Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

3BP1_MOUSE
NC score	0.026783 (rank : 508)	θ value	2.36792 (rank : 302)
Query Neighborhood Hits	437	Target Neighborhood Hits	238	Shared Neighborhood Hits	34
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

DOCK4_MOUSE
NC score	0.026493 (rank : 509)	θ value	1.38821 (rank : 265)
Query Neighborhood Hits	437	Target Neighborhood Hits	210	Shared Neighborhood Hits	28
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

CS029_MOUSE
NC score	0.026185 (rank : 510)	θ value	1.81305 (rank : 285)
Query Neighborhood Hits	437	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

CXCC1_HUMAN
NC score	0.026028 (rank : 511)	θ value	6.88961 (rank : 373)
Query Neighborhood Hits	437	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

TACC2_MOUSE
NC score	0.025794 (rank : 512)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	437	Target Neighborhood Hits	774	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

RNF12_MOUSE
NC score	0.025293 (rank : 513)	θ value	0.47712 (rank : 222)
Query Neighborhood Hits	437	Target Neighborhood Hits	159	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

INVS_MOUSE
NC score	0.025205 (rank : 514)	θ value	0.0148317 (rank : 123)
Query Neighborhood Hits	437	Target Neighborhood Hits	609	Shared Neighborhood Hits	41
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

SYGP1_HUMAN
NC score	0.024275 (rank : 515)	θ value	5.27518 (rank : 368)
Query Neighborhood Hits	437	Target Neighborhood Hits	589	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

RNF12_HUMAN
NC score	0.024189 (rank : 516)	θ value	3.0926 (rank : 325)
Query Neighborhood Hits	437	Target Neighborhood Hits	173	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

PHF22_HUMAN
NC score	0.022579 (rank : 517)	θ value	2.36792 (rank : 312)
Query Neighborhood Hits	437	Target Neighborhood Hits	121	Shared Neighborhood Hits	14
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

RBM6_HUMAN
NC score	0.022555 (rank : 518)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	437	Target Neighborhood Hits	221	Shared Neighborhood Hits	31
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

AB1IP_MOUSE
NC score	0.022432 (rank : 519)	θ value	8.99809 (rank : 397)
Query Neighborhood Hits	437	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

SFRS2_HUMAN
NC score	0.022057 (rank : 520)	θ value	4.03905 (rank : 345)
Query Neighborhood Hits	437	Target Neighborhood Hits	222	Shared Neighborhood Hits	29
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
NC score	0.022057 (rank : 521)	θ value	4.03905 (rank : 346)
Query Neighborhood Hits	437	Target Neighborhood Hits	222	Shared Neighborhood Hits	29
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

JHD2C_MOUSE
NC score	0.021750 (rank : 522)	θ value	1.81305 (rank : 289)
Query Neighborhood Hits	437	Target Neighborhood Hits	297	Shared Neighborhood Hits	42
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

JHD2C_HUMAN
NC score	0.021673 (rank : 523)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	437	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

CACB2_HUMAN
NC score	0.021568 (rank : 524)	θ value	8.99809 (rank : 402)
Query Neighborhood Hits	437	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

XE7_HUMAN
NC score	0.021366 (rank : 525)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	437	Target Neighborhood Hits	738	Shared Neighborhood Hits	47
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

RIF1_MOUSE
NC score	0.020966 (rank : 526)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	437	Target Neighborhood Hits	315	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

ZN638_MOUSE
NC score	0.020740 (rank : 527)	θ value	4.03905 (rank : 350)
Query Neighborhood Hits	437	Target Neighborhood Hits	318	Shared Neighborhood Hits	34
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

GP179_HUMAN
NC score	0.020671 (rank : 528)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	437	Target Neighborhood Hits	372	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

RBM16_HUMAN
NC score	0.020437 (rank : 529)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	437	Target Neighborhood Hits	300	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

DCC_MOUSE
NC score	0.019998 (rank : 530)	θ value	0.0563607 (rank : 154)
Query Neighborhood Hits	437	Target Neighborhood Hits	896	Shared Neighborhood Hits	34
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

COIA1_MOUSE
NC score	0.019901 (rank : 531)	θ value	0.47712 (rank : 216)
Query Neighborhood Hits	437	Target Neighborhood Hits	481	Shared Neighborhood Hits	39
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CD2L7_HUMAN
NC score	0.019834 (rank : 532)	θ value	0.813845 (rank : 241)
Query Neighborhood Hits	437	Target Neighborhood Hits	1275	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

AKAP2_HUMAN
NC score	0.019601 (rank : 533)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	437	Target Neighborhood Hits	507	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

NADAP_HUMAN
NC score	0.019511 (rank : 534)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	437	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

RM23_HUMAN
NC score	0.019465 (rank : 535)	θ value	3.0926 (rank : 324)
Query Neighborhood Hits	437	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q16540, Q96Q71	Gene names	MRPL23, L23MRP, RPL23L
Domain Architecture	No domain graphic available
Description	Mitochondrial 39S ribosomal protein L23 (L23mt) (MRP-L23) (L23 mitochondrial-related protein) (Ribosomal protein L23-like).

CHD1_HUMAN
NC score	0.019264 (rank : 536)	θ value	5.27518 (rank : 354)
Query Neighborhood Hits	437	Target Neighborhood Hits	337	Shared Neighborhood Hits	39
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

TDRD6_MOUSE
NC score	0.018451 (rank : 537)	θ value	5.27518 (rank : 369)
Query Neighborhood Hits	437	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

DCAK3_MOUSE
NC score	0.017740 (rank : 538)	θ value	0.365318 (rank : 207)
Query Neighborhood Hits	437	Target Neighborhood Hits	922	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

CDKL5_HUMAN
NC score	0.017607 (rank : 539)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	437	Target Neighborhood Hits	967	Shared Neighborhood Hits	56
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

TTBK1_HUMAN
NC score	0.017552 (rank : 540)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	437	Target Neighborhood Hits	1058	Shared Neighborhood Hits	77
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

PCNT_HUMAN
NC score	0.017447 (rank : 541)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	437	Target Neighborhood Hits	1551	Shared Neighborhood Hits	62
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

BRWD1_MOUSE
NC score	0.017252 (rank : 542)	θ value	0.0252991 (rank : 133)
Query Neighborhood Hits	437	Target Neighborhood Hits	478	Shared Neighborhood Hits	34
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CD2_HUMAN
NC score	0.016862 (rank : 543)	θ value	8.99809 (rank : 403)
Query Neighborhood Hits	437	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

TRA2B_HUMAN
NC score	0.016649 (rank : 544)	θ value	1.38821 (rank : 279)
Query Neighborhood Hits	437	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	P62995, O15449, Q15815, Q64283	Gene names	SFRS10, TRA2B
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich-splicing factor 10 (Transformer-2-beta) (HTRA2- beta) (Transformer 2 protein homolog).

TRA2B_MOUSE
NC score	0.016649 (rank : 545)	θ value	1.38821 (rank : 280)
Query Neighborhood Hits	437	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	P62996, O15449, Q15815, Q64283	Gene names	Sfrs10, Silg41, Tra2b
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich-splicing factor 10 (Transformer-2-beta) (HTRA2- beta) (Transformer 2 protein homolog) (Silica-induced gene 41 protein) (SIG-41).

CI039_HUMAN
NC score	0.016546 (rank : 546)	θ value	8.99809 (rank : 404)
Query Neighborhood Hits	437	Target Neighborhood Hits	1171	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

TXLNB_HUMAN
NC score	0.016253 (rank : 547)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	437	Target Neighborhood Hits	912	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

DCC_HUMAN
NC score	0.016068 (rank : 548)	θ value	0.0431538 (rank : 143)
Query Neighborhood Hits	437	Target Neighborhood Hits	583	Shared Neighborhood Hits	17
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

ABL1_HUMAN
NC score	0.016034 (rank : 549)	θ value	0.279714 (rank : 200)
Query Neighborhood Hits	437	Target Neighborhood Hits	1220	Shared Neighborhood Hits	58
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

FA13C_MOUSE
NC score	0.015681 (rank : 550)	θ value	8.99809 (rank : 407)
Query Neighborhood Hits	437	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

HNF1B_MOUSE
NC score	0.015678 (rank : 551)	θ value	1.06291 (rank : 257)
Query Neighborhood Hits	437	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

ETV3_HUMAN
NC score	0.015223 (rank : 552)	θ value	1.38821 (rank : 267)
Query Neighborhood Hits	437	Target Neighborhood Hits	312	Shared Neighborhood Hits	29
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ZMY11_HUMAN
NC score	0.014889 (rank : 553)	θ value	3.0926 (rank : 332)
Query Neighborhood Hits	437	Target Neighborhood Hits	201	Shared Neighborhood Hits	5
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

MKRN3_HUMAN
NC score	0.014835 (rank : 554)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	437	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

ZMY11_MOUSE
NC score	0.014767 (rank : 555)	θ value	3.0926 (rank : 333)
Query Neighborhood Hits	437	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

CTDP1_MOUSE
NC score	0.014745 (rank : 556)	θ value	8.99809 (rank : 405)
Query Neighborhood Hits	437	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

EEA1_HUMAN
NC score	0.014382 (rank : 557)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	437	Target Neighborhood Hits	1796	Shared Neighborhood Hits	68
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

TPR_HUMAN
NC score	0.013809 (rank : 558)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	437	Target Neighborhood Hits	1921	Shared Neighborhood Hits	87
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

NEK4_MOUSE
NC score	0.013232 (rank : 559)	θ value	1.38821 (rank : 271)
Query Neighborhood Hits	437	Target Neighborhood Hits	899	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

SUFU_HUMAN
NC score	0.012735 (rank : 560)	θ value	6.88961 (rank : 392)
Query Neighborhood Hits	437	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMX1, Q7LCP7, Q9NT90, Q9NZ07, Q9UHK2, Q9UHM8, Q9UMY0	Gene names	SUFU
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog (SUFUH).

RPB9_HUMAN
NC score	0.012441 (rank : 561)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	437	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P36954, Q6NW05	Gene names	POLR2I
Domain Architecture
Description	DNA-directed RNA polymerase II subunit I (EC 2.7.7.6) (DNA-directed RNA polymerase II 14.5 kDa polypeptide) (RPB9) (RPB14.5).

RPB9_MOUSE
NC score	0.012441 (rank : 562)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	437	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P60898	Gene names	Polr2i
Domain Architecture
Description	DNA-directed RNA polymerase II subunit I (EC 2.7.7.6) (DNA-directed RNA polymerase II 14.5 kDa polypeptide) (RPB9) (RPB14.5).

M3K3_HUMAN
NC score	0.011936 (rank : 563)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	437	Target Neighborhood Hits	885	Shared Neighborhood Hits	34
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

SUFU_MOUSE
NC score	0.011641 (rank : 564)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	437	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P7, Q8C8B4, Q99JG0, Q9D521, Q9JLU1	Gene names	Sufu
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog.

SSFA2_HUMAN
NC score	0.011513 (rank : 565)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	437	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	P28290, Q96E36	Gene names	SSFA2, CS1
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2 (Cleavage signal-1 protein) (CS-1).

GCP6_HUMAN
NC score	0.011492 (rank : 566)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	437	Target Neighborhood Hits	295	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

OSB11_MOUSE
NC score	0.011484 (rank : 567)	θ value	1.38821 (rank : 272)
Query Neighborhood Hits	437	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

MK07_HUMAN
NC score	0.011408 (rank : 568)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	437	Target Neighborhood Hits	1087	Shared Neighborhood Hits	53
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

SYFA_HUMAN
NC score	0.011373 (rank : 569)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	437	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y285, Q9NSD8, Q9Y4W8	Gene names	FARSLA, FARS, FARSA, FARSL
Domain Architecture
Description	Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase alpha chain) (PheRS) (CML33).

DDX46_HUMAN
NC score	0.011038 (rank : 570)	θ value	3.0926 (rank : 318)
Query Neighborhood Hits	437	Target Neighborhood Hits	357	Shared Neighborhood Hits	36
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

LSR_HUMAN
NC score	0.010977 (rank : 571)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	437	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

QSCN6_HUMAN
NC score	0.010810 (rank : 572)	θ value	3.0926 (rank : 323)
Query Neighborhood Hits	437	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

HPS4_HUMAN
NC score	0.010564 (rank : 573)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	437	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQG7, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38	Gene names	HPS4, KIAA1667
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog).

EEA1_MOUSE
NC score	0.010515 (rank : 574)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	437	Target Neighborhood Hits	1637	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

DDX46_MOUSE
NC score	0.010442 (rank : 575)	θ value	3.0926 (rank : 319)
Query Neighborhood Hits	437	Target Neighborhood Hits	358	Shared Neighborhood Hits	38
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DEDD2_MOUSE
NC score	0.010254 (rank : 576)	θ value	6.88961 (rank : 374)
Query Neighborhood Hits	437	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q8QZV0, Q569Y9, Q8JZV1	Gene names	Dedd2, Flame3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

PHLB2_HUMAN
NC score	0.010253 (rank : 577)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	437	Target Neighborhood Hits	964	Shared Neighborhood Hits	43
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SYAM_MOUSE
NC score	0.009576 (rank : 578)	θ value	4.03905 (rank : 348)
Query Neighborhood Hits	437	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q14CH7, Q68FH3, Q69ZM9	Gene names	Aarsl, Aars2, Kiaa1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

HDAC9_HUMAN
NC score	0.008954 (rank : 579)	θ value	3.0926 (rank : 320)
Query Neighborhood Hits	437	Target Neighborhood Hits	201	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

DHX8_HUMAN
NC score	0.008722 (rank : 580)	θ value	1.06291 (rank : 255)
Query Neighborhood Hits	437	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

BOC_HUMAN
NC score	0.008421 (rank : 581)	θ value	1.38821 (rank : 263)
Query Neighborhood Hits	437	Target Neighborhood Hits	543	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

HDAC6_HUMAN
NC score	0.008390 (rank : 582)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	437	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

BOC_MOUSE
NC score	0.008034 (rank : 583)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	437	Target Neighborhood Hits	433	Shared Neighborhood Hits	13
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

SPAG1_MOUSE
NC score	0.007851 (rank : 584)	θ value	2.36792 (rank : 317)
Query Neighborhood Hits	437	Target Neighborhood Hits	218	Shared Neighborhood Hits	12
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

K0494_MOUSE
NC score	0.007835 (rank : 585)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	437	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

FYV1_MOUSE
NC score	0.007752 (rank : 586)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	437	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FAK1_HUMAN
NC score	0.007733 (rank : 587)	θ value	1.38821 (rank : 268)
Query Neighborhood Hits	437	Target Neighborhood Hits	850	Shared Neighborhood Hits	27
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

BNIP3_MOUSE
NC score	0.007488 (rank : 588)	θ value	8.99809 (rank : 400)
Query Neighborhood Hits	437	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	O55003, Q544Y4	Gene names	Bnip3, Nip3
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.

FAK1_MOUSE
NC score	0.007164 (rank : 589)	θ value	1.38821 (rank : 269)
Query Neighborhood Hits	437	Target Neighborhood Hits	850	Shared Neighborhood Hits	25
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

RYR2_HUMAN
NC score	0.006841 (rank : 590)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	437	Target Neighborhood Hits	175	Shared Neighborhood Hits	10
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

XKR7_MOUSE
NC score	0.006841 (rank : 591)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	437	Target Neighborhood Hits	146	Shared Neighborhood Hits	14
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

I12R2_MOUSE
NC score	0.006588 (rank : 592)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	437	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

NRAP_MOUSE
NC score	0.006178 (rank : 593)	θ value	4.03905 (rank : 341)
Query Neighborhood Hits	437	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

ZEP2_HUMAN
NC score	0.005655 (rank : 594)	θ value	5.27518 (rank : 371)
Query Neighborhood Hits	437	Target Neighborhood Hits	937	Shared Neighborhood Hits	41
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

FOXB2_MOUSE
NC score	0.005358 (rank : 595)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	437	Target Neighborhood Hits	139	Shared Neighborhood Hits	14
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

ZNFX1_MOUSE
NC score	0.004825 (rank : 596)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	437	Target Neighborhood Hits	407	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADA12_MOUSE
NC score	0.004743 (rank : 597)	θ value	8.99809 (rank : 399)
Query Neighborhood Hits	437	Target Neighborhood Hits	474	Shared Neighborhood Hits	24
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

TRPC2_MOUSE
NC score	0.004426 (rank : 598)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	437	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC4_HUMAN
NC score	0.003713 (rank : 599)	θ value	5.27518 (rank : 370)
Query Neighborhood Hits	437	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

CAC1E_MOUSE
NC score	0.003195 (rank : 600)	θ value	8.99809 (rank : 401)
Query Neighborhood Hits	437	Target Neighborhood Hits	167	Shared Neighborhood Hits	22
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

LYST_HUMAN
NC score	0.002620 (rank : 601)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	437	Target Neighborhood Hits	324	Shared Neighborhood Hits	16
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

ZEP2_MOUSE
NC score	0.002493 (rank : 602)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	437	Target Neighborhood Hits	964	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

CSPG2_HUMAN
NC score	0.002389 (rank : 603)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	437	Target Neighborhood Hits	681	Shared Neighborhood Hits	30
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

HXC10_MOUSE
NC score	0.001907 (rank : 604)	θ value	4.03905 (rank : 340)
Query Neighborhood Hits	437	Target Neighborhood Hits	417	Shared Neighborhood Hits	23
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

PO3F3_MOUSE
NC score	0.001744 (rank : 605)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	437	Target Neighborhood Hits	308	Shared Neighborhood Hits	9
SwissProt Accessions	P31361	Gene names	Pou3f3, Brn-1, Brn1, Otf8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

ABCF2_MOUSE
NC score	0.001654 (rank : 606)	θ value	8.99809 (rank : 398)
Query Neighborhood Hits	437	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

PO3F3_HUMAN
NC score	0.001343 (rank : 607)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	437	Target Neighborhood Hits	311	Shared Neighborhood Hits	9
SwissProt Accessions	P20264, P78379	Gene names	POU3F3, BRN1, OTF8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

PAX3_HUMAN
NC score	0.000173 (rank : 608)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	437	Target Neighborhood Hits	513	Shared Neighborhood Hits	19
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

GP142_HUMAN
NC score	0.000085 (rank : 609)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	437	Target Neighborhood Hits	417	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z601, Q86SL3	Gene names	GPR142, PGR2
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 142 (G-protein coupled receptor PGR2).

MRP9_MOUSE
NC score	-0.000298 (rank : 610)	θ value	6.88961 (rank : 384)
Query Neighborhood Hits	437	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

R4RL1_MOUSE
NC score	-0.000377 (rank : 611)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	437	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0S5	Gene names	Rtn4rl1, Ngrl2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

PAX3_MOUSE
NC score	-0.000684 (rank : 612)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	437	Target Neighborhood Hits	478	Shared Neighborhood Hits	18
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

SUHW2_HUMAN
NC score	-0.008386 (rank : 613)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	437	Target Neighborhood Hits	683	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YH2	Gene names	SUHW2, ZNF632
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 2 (5'OY11.1) (Zinc finger protein 632).

ZBT16_HUMAN
NC score	-0.009886 (rank : 614)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	437	Target Neighborhood Hits	1010	Shared Neighborhood Hits	18
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).