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Network neighborhood for query Sequence : APBA1_HUMAN

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APBA1_HUMAN
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

APBA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	325	Target Neighborhood Hits	325	Shared Neighborhood Hits	325
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

APBA2_HUMAN
θ value	0 (rank : 2)	NC score	0.956569 (rank : 2)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	163
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0 (rank : 3)	NC score	0.955398 (rank : 3)
Query Neighborhood Hits	325	Target Neighborhood Hits	219	Shared Neighborhood Hits	159
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
θ value	3.62588e-142 (rank : 4)	NC score	0.938851 (rank : 4)
Query Neighborhood Hits	325	Target Neighborhood Hits	201	Shared Neighborhood Hits	143
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
θ value	1.12976e-135 (rank : 5)	NC score	0.934011 (rank : 5)
Query Neighborhood Hits	325	Target Neighborhood Hits	174	Shared Neighborhood Hits	141
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SDCB2_MOUSE
θ value	3.52202e-12 (rank : 6)	NC score	0.533066 (rank : 6)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	101
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_HUMAN
θ value	3.89403e-11 (rank : 7)	NC score	0.526462 (rank : 8)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	98
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB1_HUMAN
θ value	1.25267e-09 (rank : 8)	NC score	0.527186 (rank : 7)
Query Neighborhood Hits	325	Target Neighborhood Hits	150	Shared Neighborhood Hits	121
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

INADL_HUMAN
θ value	6.21693e-09 (rank : 9)	NC score	0.495356 (rank : 10)
Query Neighborhood Hits	325	Target Neighborhood Hits	260	Shared Neighborhood Hits	156
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

SDCB1_MOUSE
θ value	6.21693e-09 (rank : 10)	NC score	0.516582 (rank : 9)
Query Neighborhood Hits	325	Target Neighborhood Hits	144	Shared Neighborhood Hits	113
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

MPDZ_HUMAN
θ value	1.80886e-08 (rank : 11)	NC score	0.492603 (rank : 11)
Query Neighborhood Hits	325	Target Neighborhood Hits	261	Shared Neighborhood Hits	159
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

GRIP1_HUMAN
θ value	1.53129e-07 (rank : 12)	NC score	0.491588 (rank : 13)
Query Neighborhood Hits	325	Target Neighborhood Hits	231	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

DLG2_MOUSE
θ value	1.99992e-07 (rank : 13)	NC score	0.466468 (rank : 24)
Query Neighborhood Hits	325	Target Neighborhood Hits	271	Shared Neighborhood Hits	149
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

MPDZ_MOUSE
θ value	1.99992e-07 (rank : 14)	NC score	0.482143 (rank : 16)
Query Neighborhood Hits	325	Target Neighborhood Hits	298	Shared Neighborhood Hits	160
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

DLG2_HUMAN
θ value	2.61198e-07 (rank : 15)	NC score	0.467330 (rank : 21)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	150
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

GRIP1_MOUSE
θ value	3.41135e-07 (rank : 16)	NC score	0.491915 (rank : 12)
Query Neighborhood Hits	325	Target Neighborhood Hits	241	Shared Neighborhood Hits	152
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

INADL_MOUSE
θ value	4.45536e-07 (rank : 17)	NC score	0.483220 (rank : 15)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	155
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

GRIP2_HUMAN
θ value	1.69304e-06 (rank : 18)	NC score	0.484613 (rank : 14)
Query Neighborhood Hits	325	Target Neighborhood Hits	256	Shared Neighborhood Hits	153
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

DLG3_HUMAN
θ value	2.21117e-06 (rank : 19)	NC score	0.470733 (rank : 18)
Query Neighborhood Hits	325	Target Neighborhood Hits	269	Shared Neighborhood Hits	147
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	2.21117e-06 (rank : 20)	NC score	0.472351 (rank : 17)
Query Neighborhood Hits	325	Target Neighborhood Hits	274	Shared Neighborhood Hits	147
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG4_HUMAN
θ value	2.88788e-06 (rank : 21)	NC score	0.466525 (rank : 23)
Query Neighborhood Hits	325	Target Neighborhood Hits	286	Shared Neighborhood Hits	145
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	2.88788e-06 (rank : 22)	NC score	0.467064 (rank : 22)
Query Neighborhood Hits	325	Target Neighborhood Hits	282	Shared Neighborhood Hits	147
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG1_HUMAN
θ value	4.92598e-06 (rank : 23)	NC score	0.458297 (rank : 27)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	142
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

NOS1_HUMAN
θ value	1.09739e-05 (rank : 24)	NC score	0.271747 (rank : 113)
Query Neighborhood Hits	325	Target Neighborhood Hits	218	Shared Neighborhood Hits	133
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

DLG1_MOUSE
θ value	1.87187e-05 (rank : 25)	NC score	0.456428 (rank : 30)
Query Neighborhood Hits	325	Target Neighborhood Hits	285	Shared Neighborhood Hits	143
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

MAGI1_MOUSE
θ value	1.87187e-05 (rank : 26)	NC score	0.431783 (rank : 34)
Query Neighborhood Hits	325	Target Neighborhood Hits	403	Shared Neighborhood Hits	167
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
θ value	2.44474e-05 (rank : 27)	NC score	0.422477 (rank : 39)
Query Neighborhood Hits	325	Target Neighborhood Hits	373	Shared Neighborhood Hits	159
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	2.44474e-05 (rank : 28)	NC score	0.421086 (rank : 40)
Query Neighborhood Hits	325	Target Neighborhood Hits	370	Shared Neighborhood Hits	154
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI1_HUMAN
θ value	4.1701e-05 (rank : 29)	NC score	0.428321 (rank : 35)
Query Neighborhood Hits	325	Target Neighborhood Hits	388	Shared Neighborhood Hits	170
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

NOS1_MOUSE
θ value	7.1131e-05 (rank : 30)	NC score	0.244487 (rank : 119)
Query Neighborhood Hits	325	Target Neighborhood Hits	155	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

MPP4_HUMAN
θ value	0.000158464 (rank : 31)	NC score	0.414061 (rank : 44)
Query Neighborhood Hits	325	Target Neighborhood Hits	205	Shared Neighborhood Hits	130
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

LIN7C_HUMAN
θ value	0.000270298 (rank : 32)	NC score	0.470131 (rank : 19)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.000270298 (rank : 33)	NC score	0.470131 (rank : 20)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	150
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

MPP5_MOUSE
θ value	0.000270298 (rank : 34)	NC score	0.385832 (rank : 56)
Query Neighborhood Hits	325	Target Neighborhood Hits	226	Shared Neighborhood Hits	124
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP4_MOUSE
θ value	0.00035302 (rank : 35)	NC score	0.387906 (rank : 54)
Query Neighborhood Hits	325	Target Neighborhood Hits	188	Shared Neighborhood Hits	121
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

LAP4_HUMAN
θ value	0.000461057 (rank : 36)	NC score	0.293546 (rank : 101)
Query Neighborhood Hits	325	Target Neighborhood Hits	608	Shared Neighborhood Hits	168
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PAR3L_HUMAN
θ value	0.000461057 (rank : 37)	NC score	0.449692 (rank : 31)
Query Neighborhood Hits	325	Target Neighborhood Hits	297	Shared Neighborhood Hits	141
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

NEB2_HUMAN
θ value	0.000602161 (rank : 38)	NC score	0.302198 (rank : 95)
Query Neighborhood Hits	325	Target Neighborhood Hits	883	Shared Neighborhood Hits	138
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	0.000602161 (rank : 39)	NC score	0.298481 (rank : 98)
Query Neighborhood Hits	325	Target Neighborhood Hits	889	Shared Neighborhood Hits	138
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SHC1_HUMAN
θ value	0.000602161 (rank : 40)	NC score	0.144317 (rank : 153)
Query Neighborhood Hits	325	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	0.000602161 (rank : 41)	NC score	0.143008 (rank : 154)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC3_HUMAN
θ value	0.000602161 (rank : 42)	NC score	0.159778 (rank : 147)
Query Neighborhood Hits	325	Target Neighborhood Hits	155	Shared Neighborhood Hits	14
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

USH1C_MOUSE
θ value	0.000602161 (rank : 43)	NC score	0.427369 (rank : 36)
Query Neighborhood Hits	325	Target Neighborhood Hits	557	Shared Neighborhood Hits	162
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

LIN7B_HUMAN
θ value	0.000786445 (rank : 44)	NC score	0.462699 (rank : 25)
Query Neighborhood Hits	325	Target Neighborhood Hits	200	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LNX1_HUMAN
θ value	0.000786445 (rank : 45)	NC score	0.404195 (rank : 48)
Query Neighborhood Hits	325	Target Neighborhood Hits	379	Shared Neighborhood Hits	140
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MPP3_HUMAN
θ value	0.000786445 (rank : 46)	NC score	0.397462 (rank : 51)
Query Neighborhood Hits	325	Target Neighborhood Hits	171	Shared Neighborhood Hits	126
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	0.000786445 (rank : 47)	NC score	0.399382 (rank : 50)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	126
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

ANKS1_HUMAN
θ value	0.00102713 (rank : 48)	NC score	0.067030 (rank : 204)
Query Neighborhood Hits	325	Target Neighborhood Hits	438	Shared Neighborhood Hits	23
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
θ value	0.00102713 (rank : 49)	NC score	0.074191 (rank : 197)
Query Neighborhood Hits	325	Target Neighborhood Hits	453	Shared Neighborhood Hits	25
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

EM55_HUMAN
θ value	0.00102713 (rank : 50)	NC score	0.370345 (rank : 59)
Query Neighborhood Hits	325	Target Neighborhood Hits	228	Shared Neighborhood Hits	118
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

LIN7B_MOUSE
θ value	0.00102713 (rank : 51)	NC score	0.460746 (rank : 26)
Query Neighborhood Hits	325	Target Neighborhood Hits	200	Shared Neighborhood Hits	150
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

MPP5_HUMAN
θ value	0.00102713 (rank : 52)	NC score	0.386778 (rank : 55)
Query Neighborhood Hits	325	Target Neighborhood Hits	231	Shared Neighborhood Hits	124
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP6_MOUSE
θ value	0.00102713 (rank : 53)	NC score	0.338225 (rank : 75)
Query Neighborhood Hits	325	Target Neighborhood Hits	187	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

RP1L1_HUMAN
θ value	0.00102713 (rank : 54)	NC score	0.065012 (rank : 208)
Query Neighborhood Hits	325	Target Neighborhood Hits	1072	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

DLG5_HUMAN
θ value	0.00134147 (rank : 55)	NC score	0.300145 (rank : 96)
Query Neighborhood Hits	325	Target Neighborhood Hits	1088	Shared Neighborhood Hits	160
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

LNX1_MOUSE
θ value	0.00134147 (rank : 56)	NC score	0.403137 (rank : 49)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	147
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MPP6_HUMAN
θ value	0.00134147 (rank : 57)	NC score	0.337239 (rank : 77)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

RIMB1_HUMAN
θ value	0.00134147 (rank : 58)	NC score	0.067011 (rank : 205)
Query Neighborhood Hits	325	Target Neighborhood Hits	1479	Shared Neighborhood Hits	87
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SHC3_MOUSE
θ value	0.00134147 (rank : 59)	NC score	0.157216 (rank : 148)
Query Neighborhood Hits	325	Target Neighborhood Hits	151	Shared Neighborhood Hits	15
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

CSKP_HUMAN
θ value	0.00175202 (rank : 60)	NC score	0.129338 (rank : 158)
Query Neighborhood Hits	325	Target Neighborhood Hits	1022	Shared Neighborhood Hits	120
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	0.00175202 (rank : 61)	NC score	0.128703 (rank : 159)
Query Neighborhood Hits	325	Target Neighborhood Hits	1027	Shared Neighborhood Hits	120
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

EM55_MOUSE
θ value	0.00175202 (rank : 62)	NC score	0.369491 (rank : 60)
Query Neighborhood Hits	325	Target Neighborhood Hits	221	Shared Neighborhood Hits	117
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

LIN7A_HUMAN
θ value	0.00175202 (rank : 63)	NC score	0.457912 (rank : 29)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	148
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	0.00175202 (rank : 64)	NC score	0.458073 (rank : 28)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	148
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

SHAN1_HUMAN
θ value	0.00175202 (rank : 65)	NC score	0.178512 (rank : 140)
Query Neighborhood Hits	325	Target Neighborhood Hits	1041	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

USH1C_HUMAN
θ value	0.00175202 (rank : 66)	NC score	0.445736 (rank : 32)
Query Neighborhood Hits	325	Target Neighborhood Hits	327	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

NEB1_HUMAN
θ value	0.00228821 (rank : 67)	NC score	0.311871 (rank : 87)
Query Neighborhood Hits	325	Target Neighborhood Hits	829	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PDZD7_HUMAN
θ value	0.00228821 (rank : 68)	NC score	0.443793 (rank : 33)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	136
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

CB013_MOUSE
θ value	0.00298849 (rank : 69)	NC score	0.082264 (rank : 191)
Query Neighborhood Hits	325	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D842, Q8BZL5, Q99LX6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13 homolog.

PTN13_HUMAN
θ value	0.00298849 (rank : 70)	NC score	0.254331 (rank : 116)
Query Neighborhood Hits	325	Target Neighborhood Hits	471	Shared Neighborhood Hits	162
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

STXB4_MOUSE
θ value	0.00298849 (rank : 71)	NC score	0.259398 (rank : 115)
Query Neighborhood Hits	325	Target Neighborhood Hits	629	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

K1849_HUMAN
θ value	0.00390308 (rank : 72)	NC score	0.368727 (rank : 62)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	126
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PDZD1_MOUSE
θ value	0.00390308 (rank : 73)	NC score	0.415152 (rank : 42)
Query Neighborhood Hits	325	Target Neighborhood Hits	191	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

STXB4_HUMAN
θ value	0.00390308 (rank : 74)	NC score	0.259838 (rank : 114)
Query Neighborhood Hits	325	Target Neighborhood Hits	616	Shared Neighborhood Hits	101
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

LAP4_MOUSE
θ value	0.00665767 (rank : 75)	NC score	0.286970 (rank : 102)
Query Neighborhood Hits	325	Target Neighborhood Hits	590	Shared Neighborhood Hits	170
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PARD3_HUMAN
θ value	0.00665767 (rank : 76)	NC score	0.427038 (rank : 37)
Query Neighborhood Hits	325	Target Neighborhood Hits	312	Shared Neighborhood Hits	157
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PTN13_MOUSE
θ value	0.00665767 (rank : 77)	NC score	0.249026 (rank : 117)
Query Neighborhood Hits	325	Target Neighborhood Hits	426	Shared Neighborhood Hits	156
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

WHRN_HUMAN
θ value	0.00665767 (rank : 78)	NC score	0.418170 (rank : 41)
Query Neighborhood Hits	325	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	0.00665767 (rank : 79)	NC score	0.414138 (rank : 43)
Query Neighborhood Hits	325	Target Neighborhood Hits	412	Shared Neighborhood Hits	159
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

FOXD1_HUMAN
θ value	0.00869519 (rank : 80)	NC score	0.017070 (rank : 316)
Query Neighborhood Hits	325	Target Neighborhood Hits	122	Shared Neighborhood Hits	6
SwissProt Accessions	Q16676, Q12949	Gene names	FOXD1, FKHL8, FREAC4
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4).

GOPC_HUMAN
θ value	0.00869519 (rank : 81)	NC score	0.404207 (rank : 47)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	136
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	0.00869519 (rank : 82)	NC score	0.410015 (rank : 45)
Query Neighborhood Hits	325	Target Neighborhood Hits	323	Shared Neighborhood Hits	136
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LNX2_MOUSE
θ value	0.0113563 (rank : 83)	NC score	0.392187 (rank : 53)
Query Neighborhood Hits	325	Target Neighborhood Hits	407	Shared Neighborhood Hits	148
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

AFAD_HUMAN
θ value	0.0148317 (rank : 84)	NC score	0.322948 (rank : 82)
Query Neighborhood Hits	325	Target Neighborhood Hits	689	Shared Neighborhood Hits	145
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AN32B_HUMAN
θ value	0.0148317 (rank : 85)	NC score	0.043150 (rank : 240)
Query Neighborhood Hits	325	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

K1849_MOUSE
θ value	0.0148317 (rank : 86)	NC score	0.348501 (rank : 70)
Query Neighborhood Hits	325	Target Neighborhood Hits	335	Shared Neighborhood Hits	154
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PARD3_MOUSE
θ value	0.0148317 (rank : 87)	NC score	0.426574 (rank : 38)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	150
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDZD2_HUMAN
θ value	0.0148317 (rank : 88)	NC score	0.405377 (rank : 46)
Query Neighborhood Hits	325	Target Neighborhood Hits	772	Shared Neighborhood Hits	173
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RGS12_HUMAN
θ value	0.0148317 (rank : 89)	NC score	0.207607 (rank : 131)
Query Neighborhood Hits	325	Target Neighborhood Hits	333	Shared Neighborhood Hits	128
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SNTB2_MOUSE
θ value	0.0148317 (rank : 90)	NC score	0.337900 (rank : 76)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	132
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

FYB_HUMAN
θ value	0.0193708 (rank : 91)	NC score	0.057470 (rank : 216)
Query Neighborhood Hits	325	Target Neighborhood Hits	379	Shared Neighborhood Hits	37
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

MPP2_HUMAN
θ value	0.0193708 (rank : 92)	NC score	0.330120 (rank : 81)
Query Neighborhood Hits	325	Target Neighborhood Hits	173	Shared Neighborhood Hits	92
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	0.0193708 (rank : 93)	NC score	0.335243 (rank : 78)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

SVIL_MOUSE
θ value	0.0193708 (rank : 94)	NC score	0.040058 (rank : 244)
Query Neighborhood Hits	325	Target Neighborhood Hits	439	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

ARHGC_HUMAN
θ value	0.0252991 (rank : 95)	NC score	0.212307 (rank : 129)
Query Neighborhood Hits	325	Target Neighborhood Hits	351	Shared Neighborhood Hits	124
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

JIP1_HUMAN
θ value	0.0252991 (rank : 96)	NC score	0.116486 (rank : 167)
Query Neighborhood Hits	325	Target Neighborhood Hits	271	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

PREX1_HUMAN
θ value	0.0252991 (rank : 97)	NC score	0.066309 (rank : 206)
Query Neighborhood Hits	325	Target Neighborhood Hits	177	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

ARHGC_MOUSE
θ value	0.0330416 (rank : 98)	NC score	0.209052 (rank : 130)
Query Neighborhood Hits	325	Target Neighborhood Hits	344	Shared Neighborhood Hits	126
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

IF39_MOUSE
θ value	0.0330416 (rank : 99)	NC score	0.049112 (rank : 226)
Query Neighborhood Hits	325	Target Neighborhood Hits	206	Shared Neighborhood Hits	17
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

PKHA6_HUMAN
θ value	0.0330416 (rank : 100)	NC score	0.047231 (rank : 230)
Query Neighborhood Hits	325	Target Neighborhood Hits	556	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SNTB2_HUMAN
θ value	0.0330416 (rank : 101)	NC score	0.333254 (rank : 79)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	131
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

JIP1_MOUSE
θ value	0.0431538 (rank : 102)	NC score	0.111957 (rank : 169)
Query Neighborhood Hits	325	Target Neighborhood Hits	259	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

LNX2_HUMAN
θ value	0.0431538 (rank : 103)	NC score	0.395083 (rank : 52)
Query Neighborhood Hits	325	Target Neighborhood Hits	389	Shared Neighborhood Hits	147
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RGS3_MOUSE
θ value	0.0431538 (rank : 104)	NC score	0.073907 (rank : 198)
Query Neighborhood Hits	325	Target Neighborhood Hits	1621	Shared Neighborhood Hits	151
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SI1L2_HUMAN
θ value	0.0431538 (rank : 105)	NC score	0.128323 (rank : 160)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	0.0431538 (rank : 106)	NC score	0.126227 (rank : 161)
Query Neighborhood Hits	325	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

ARHGB_HUMAN
θ value	0.0563607 (rank : 107)	NC score	0.219393 (rank : 126)
Query Neighborhood Hits	325	Target Neighborhood Hits	375	Shared Neighborhood Hits	132
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SHAN2_HUMAN
θ value	0.0563607 (rank : 108)	NC score	0.246774 (rank : 118)
Query Neighborhood Hits	325	Target Neighborhood Hits	346	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	0.0563607 (rank : 109)	NC score	0.225851 (rank : 124)
Query Neighborhood Hits	325	Target Neighborhood Hits	446	Shared Neighborhood Hits	115
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SNTG2_HUMAN
θ value	0.0563607 (rank : 110)	NC score	0.339246 (rank : 74)
Query Neighborhood Hits	325	Target Neighborhood Hits	191	Shared Neighborhood Hits	146
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

MAST3_HUMAN
θ value	0.0736092 (rank : 111)	NC score	0.051759 (rank : 222)
Query Neighborhood Hits	325	Target Neighborhood Hits	1128	Shared Neighborhood Hits	106
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

PDZD3_HUMAN
θ value	0.0736092 (rank : 112)	NC score	0.381444 (rank : 57)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	135
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PICK1_HUMAN
θ value	0.0736092 (rank : 113)	NC score	0.316209 (rank : 85)
Query Neighborhood Hits	325	Target Neighborhood Hits	132	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	0.0736092 (rank : 114)	NC score	0.316292 (rank : 84)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	111
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

SI1L1_HUMAN
θ value	0.0736092 (rank : 115)	NC score	0.121276 (rank : 164)
Query Neighborhood Hits	325	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
θ value	0.0736092 (rank : 116)	NC score	0.120983 (rank : 165)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	46
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

NFH_HUMAN
θ value	0.0961366 (rank : 117)	NC score	0.026057 (rank : 285)
Query Neighborhood Hits	325	Target Neighborhood Hits	1242	Shared Neighborhood Hits	58
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SI1L3_HUMAN
θ value	0.0961366 (rank : 118)	NC score	0.122378 (rank : 162)
Query Neighborhood Hits	325	Target Neighborhood Hits	305	Shared Neighborhood Hits	44
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

ZO2_HUMAN
θ value	0.0961366 (rank : 119)	NC score	0.305333 (rank : 93)
Query Neighborhood Hits	325	Target Neighborhood Hits	289	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

BASP_HUMAN
θ value	0.125558 (rank : 120)	NC score	0.054778 (rank : 219)
Query Neighborhood Hits	325	Target Neighborhood Hits	321	Shared Neighborhood Hits	26
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CO7A1_HUMAN
θ value	0.125558 (rank : 121)	NC score	0.035786 (rank : 263)
Query Neighborhood Hits	325	Target Neighborhood Hits	807	Shared Neighborhood Hits	59
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

PAR6A_HUMAN
θ value	0.125558 (rank : 122)	NC score	0.298227 (rank : 99)
Query Neighborhood Hits	325	Target Neighborhood Hits	119	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	0.125558 (rank : 123)	NC score	0.299349 (rank : 97)
Query Neighborhood Hits	325	Target Neighborhood Hits	115	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6G_HUMAN
θ value	0.125558 (rank : 124)	NC score	0.284989 (rank : 105)
Query Neighborhood Hits	325	Target Neighborhood Hits	159	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	0.125558 (rank : 125)	NC score	0.284243 (rank : 106)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PZRN4_HUMAN
θ value	0.125558 (rank : 126)	NC score	0.295750 (rank : 100)
Query Neighborhood Hits	325	Target Neighborhood Hits	438	Shared Neighborhood Hits	133
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZO2_MOUSE
θ value	0.125558 (rank : 127)	NC score	0.306875 (rank : 91)
Query Neighborhood Hits	325	Target Neighborhood Hits	296	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

MAST1_MOUSE
θ value	0.163984 (rank : 128)	NC score	0.047843 (rank : 228)
Query Neighborhood Hits	325	Target Neighborhood Hits	1123	Shared Neighborhood Hits	114
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SSXT_MOUSE
θ value	0.163984 (rank : 129)	NC score	0.047335 (rank : 229)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

EMID2_HUMAN
θ value	0.21417 (rank : 130)	NC score	0.037895 (rank : 255)
Query Neighborhood Hits	325	Target Neighborhood Hits	226	Shared Neighborhood Hits	33
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

MYRIP_HUMAN
θ value	0.21417 (rank : 131)	NC score	0.033824 (rank : 266)
Query Neighborhood Hits	325	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

SSXT_HUMAN
θ value	0.21417 (rank : 132)	NC score	0.045960 (rank : 238)
Query Neighborhood Hits	325	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

BC11B_MOUSE
θ value	0.279714 (rank : 133)	NC score	0.001619 (rank : 367)
Query Neighborhood Hits	325	Target Neighborhood Hits	767	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

CCD55_HUMAN
θ value	0.279714 (rank : 134)	NC score	0.033790 (rank : 267)
Query Neighborhood Hits	325	Target Neighborhood Hits	513	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

GIPC2_HUMAN
θ value	0.279714 (rank : 135)	NC score	0.162201 (rank : 145)
Query Neighborhood Hits	325	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

NFM_MOUSE
θ value	0.279714 (rank : 136)	NC score	0.019438 (rank : 308)
Query Neighborhood Hits	325	Target Neighborhood Hits	1159	Shared Neighborhood Hits	52
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NHERF_HUMAN
θ value	0.279714 (rank : 137)	NC score	0.351250 (rank : 67)
Query Neighborhood Hits	325	Target Neighborhood Hits	190	Shared Neighborhood Hits	127
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
θ value	0.279714 (rank : 138)	NC score	0.362349 (rank : 63)
Query Neighborhood Hits	325	Target Neighborhood Hits	195	Shared Neighborhood Hits	130
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

OXSR1_MOUSE
θ value	0.279714 (rank : 139)	NC score	0.004210 (rank : 358)
Query Neighborhood Hits	325	Target Neighborhood Hits	865	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

PABP2_HUMAN
θ value	0.279714 (rank : 140)	NC score	0.036336 (rank : 261)
Query Neighborhood Hits	325	Target Neighborhood Hits	212	Shared Neighborhood Hits	12
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PCLO_MOUSE
θ value	0.279714 (rank : 141)	NC score	0.134537 (rank : 156)
Query Neighborhood Hits	325	Target Neighborhood Hits	2275	Shared Neighborhood Hits	206
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDZD3_MOUSE
θ value	0.279714 (rank : 142)	NC score	0.353984 (rank : 66)
Query Neighborhood Hits	325	Target Neighborhood Hits	171	Shared Neighborhood Hits	127
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SRCH_HUMAN
θ value	0.279714 (rank : 143)	NC score	0.046803 (rank : 233)
Query Neighborhood Hits	325	Target Neighborhood Hits	225	Shared Neighborhood Hits	20
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TXND2_MOUSE
θ value	0.279714 (rank : 144)	NC score	0.039411 (rank : 249)
Query Neighborhood Hits	325	Target Neighborhood Hits	828	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZO3_MOUSE
θ value	0.279714 (rank : 145)	NC score	0.348031 (rank : 71)
Query Neighborhood Hits	325	Target Neighborhood Hits	224	Shared Neighborhood Hits	142
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

BASP_MOUSE
θ value	0.365318 (rank : 146)	NC score	0.065453 (rank : 207)
Query Neighborhood Hits	325	Target Neighborhood Hits	260	Shared Neighborhood Hits	29
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MAST1_HUMAN
θ value	0.365318 (rank : 147)	NC score	0.046578 (rank : 236)
Query Neighborhood Hits	325	Target Neighborhood Hits	1146	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

RED1_MOUSE
θ value	0.365318 (rank : 148)	NC score	0.020868 (rank : 303)
Query Neighborhood Hits	325	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZS8, Q8K3X1, Q91ZS6, Q91ZS7, Q91ZS9, Q99MU8	Gene names	Adarb1, Adar2, Red1
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RIMB1_MOUSE
θ value	0.365318 (rank : 149)	NC score	0.047153 (rank : 231)
Query Neighborhood Hits	325	Target Neighborhood Hits	1376	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZN335_HUMAN
θ value	0.365318 (rank : 150)	NC score	0.001698 (rank : 366)
Query Neighborhood Hits	325	Target Neighborhood Hits	973	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

CTDP1_MOUSE
θ value	0.47712 (rank : 151)	NC score	0.046787 (rank : 234)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DVL1L_HUMAN
θ value	0.47712 (rank : 152)	NC score	0.228705 (rank : 121)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	104
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

GLU2B_HUMAN
θ value	0.47712 (rank : 153)	NC score	0.029948 (rank : 276)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	19
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

MYST3_MOUSE
θ value	0.47712 (rank : 154)	NC score	0.025735 (rank : 286)
Query Neighborhood Hits	325	Target Neighborhood Hits	688	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NALP5_MOUSE
θ value	0.47712 (rank : 155)	NC score	0.023390 (rank : 295)
Query Neighborhood Hits	325	Target Neighborhood Hits	560	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PDZD1_HUMAN
θ value	0.47712 (rank : 156)	NC score	0.380770 (rank : 58)
Query Neighborhood Hits	325	Target Neighborhood Hits	190	Shared Neighborhood Hits	128
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SNTG2_MOUSE
θ value	0.47712 (rank : 157)	NC score	0.305351 (rank : 92)
Query Neighborhood Hits	325	Target Neighborhood Hits	176	Shared Neighborhood Hits	136
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

ZO3_HUMAN
θ value	0.47712 (rank : 158)	NC score	0.345289 (rank : 72)
Query Neighborhood Hits	325	Target Neighborhood Hits	219	Shared Neighborhood Hits	138
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

COEA1_MOUSE
θ value	0.62314 (rank : 159)	NC score	0.024834 (rank : 290)
Query Neighborhood Hits	325	Target Neighborhood Hits	402	Shared Neighborhood Hits	35
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

LSP1_MOUSE
θ value	0.62314 (rank : 160)	NC score	0.040072 (rank : 242)
Query Neighborhood Hits	325	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

RHPN1_MOUSE
θ value	0.62314 (rank : 161)	NC score	0.194329 (rank : 134)
Query Neighborhood Hits	325	Target Neighborhood Hits	154	Shared Neighborhood Hits	102
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SNTG1_MOUSE
θ value	0.62314 (rank : 162)	NC score	0.310036 (rank : 88)
Query Neighborhood Hits	325	Target Neighborhood Hits	179	Shared Neighborhood Hits	136
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

CCDC9_MOUSE
θ value	0.813845 (rank : 163)	NC score	0.035907 (rank : 262)
Query Neighborhood Hits	325	Target Neighborhood Hits	196	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CENPB_HUMAN
θ value	0.813845 (rank : 164)	NC score	0.032184 (rank : 271)
Query Neighborhood Hits	325	Target Neighborhood Hits	133	Shared Neighborhood Hits	15
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

PEG3_HUMAN
θ value	0.813845 (rank : 165)	NC score	-0.001925 (rank : 376)
Query Neighborhood Hits	325	Target Neighborhood Hits	800	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

PELP1_HUMAN
θ value	0.813845 (rank : 166)	NC score	0.038008 (rank : 252)
Query Neighborhood Hits	325	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PZRN3_MOUSE
θ value	0.813845 (rank : 167)	NC score	0.286251 (rank : 104)
Query Neighborhood Hits	325	Target Neighborhood Hits	447	Shared Neighborhood Hits	131
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RIMS2_HUMAN
θ value	0.813845 (rank : 168)	NC score	0.122064 (rank : 163)
Query Neighborhood Hits	325	Target Neighborhood Hits	342	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.813845 (rank : 169)	NC score	0.119461 (rank : 166)
Query Neighborhood Hits	325	Target Neighborhood Hits	376	Shared Neighborhood Hits	99
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SNTG1_HUMAN
θ value	0.813845 (rank : 170)	NC score	0.308361 (rank : 90)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

CO3A1_MOUSE
θ value	1.06291 (rank : 171)	NC score	0.039991 (rank : 245)
Query Neighborhood Hits	325	Target Neighborhood Hits	466	Shared Neighborhood Hits	45
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CUTL1_HUMAN
θ value	1.06291 (rank : 172)	NC score	0.014745 (rank : 321)
Query Neighborhood Hits	325	Target Neighborhood Hits	1574	Shared Neighborhood Hits	51
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

FOXQ1_HUMAN
θ value	1.06291 (rank : 173)	NC score	0.011652 (rank : 331)
Query Neighborhood Hits	325	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

JIP2_HUMAN
θ value	1.06291 (rank : 174)	NC score	0.079113 (rank : 193)
Query Neighborhood Hits	325	Target Neighborhood Hits	288	Shared Neighborhood Hits	36
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

NFH_MOUSE
θ value	1.06291 (rank : 175)	NC score	0.046552 (rank : 237)
Query Neighborhood Hits	325	Target Neighborhood Hits	2247	Shared Neighborhood Hits	135
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PAR6B_HUMAN
θ value	1.06291 (rank : 176)	NC score	0.272471 (rank : 112)
Query Neighborhood Hits	325	Target Neighborhood Hits	126	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	1.06291 (rank : 177)	NC score	0.273953 (rank : 110)
Query Neighborhood Hits	325	Target Neighborhood Hits	128	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PZRN3_HUMAN
θ value	1.06291 (rank : 178)	NC score	0.282022 (rank : 108)
Query Neighborhood Hits	325	Target Neighborhood Hits	461	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SCN4A_HUMAN
θ value	1.06291 (rank : 179)	NC score	0.008501 (rank : 345)
Query Neighborhood Hits	325	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

TCAL5_MOUSE
θ value	1.06291 (rank : 180)	NC score	0.026709 (rank : 281)
Query Neighborhood Hits	325	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CCT4, Q497R6	Gene names	Tceal5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

AN32B_MOUSE
θ value	1.38821 (rank : 181)	NC score	0.034062 (rank : 265)
Query Neighborhood Hits	325	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

DGLA_HUMAN
θ value	1.38821 (rank : 182)	NC score	0.018628 (rank : 310)
Query Neighborhood Hits	325	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4D2, Q6WQJ0	Gene names	NSDDR, C11orf11, KIAA0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

ERCC6_HUMAN
θ value	1.38821 (rank : 183)	NC score	0.009651 (rank : 341)
Query Neighborhood Hits	325	Target Neighborhood Hits	247	Shared Neighborhood Hits	15
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

IL16_HUMAN
θ value	1.38821 (rank : 184)	NC score	0.339960 (rank : 73)
Query Neighborhood Hits	325	Target Neighborhood Hits	207	Shared Neighborhood Hits	124
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

MAST2_HUMAN
θ value	1.38821 (rank : 185)	NC score	0.046830 (rank : 232)
Query Neighborhood Hits	325	Target Neighborhood Hits	1189	Shared Neighborhood Hits	115
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	1.38821 (rank : 186)	NC score	0.045310 (rank : 239)
Query Neighborhood Hits	325	Target Neighborhood Hits	1110	Shared Neighborhood Hits	109
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NHRF2_HUMAN
θ value	1.38821 (rank : 187)	NC score	0.359138 (rank : 64)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	135
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PKHA6_MOUSE
θ value	1.38821 (rank : 188)	NC score	0.037182 (rank : 259)
Query Neighborhood Hits	325	Target Neighborhood Hits	591	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PRKDC_HUMAN
θ value	1.38821 (rank : 189)	NC score	0.014443 (rank : 322)
Query Neighborhood Hits	325	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

RNZ2_MOUSE
θ value	1.38821 (rank : 190)	NC score	0.021818 (rank : 301)
Query Neighborhood Hits	325	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y81, Q99MF0, Q99MF1, Q9CTA2, Q9D1A8, Q9EPZ2	Gene names	Elac2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2).

RREB1_HUMAN
θ value	1.38821 (rank : 191)	NC score	0.002116 (rank : 365)
Query Neighborhood Hits	325	Target Neighborhood Hits	879	Shared Neighborhood Hits	29
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SFTPD_MOUSE
θ value	1.38821 (rank : 192)	NC score	0.026337 (rank : 284)
Query Neighborhood Hits	325	Target Neighborhood Hits	217	Shared Neighborhood Hits	29
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

TITIN_HUMAN
θ value	1.38821 (rank : 193)	NC score	0.011000 (rank : 333)
Query Neighborhood Hits	325	Target Neighborhood Hits	2923	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CABL2_MOUSE
θ value	1.81305 (rank : 194)	NC score	0.020824 (rank : 304)
Query Neighborhood Hits	325	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

COEA1_HUMAN
θ value	1.81305 (rank : 195)	NC score	0.027616 (rank : 279)
Query Neighborhood Hits	325	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CTDP1_HUMAN
θ value	1.81305 (rank : 196)	NC score	0.051360 (rank : 223)
Query Neighborhood Hits	325	Target Neighborhood Hits	416	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DVL1_HUMAN
θ value	1.81305 (rank : 197)	NC score	0.228177 (rank : 123)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	107
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

KLF13_HUMAN
θ value	1.81305 (rank : 198)	NC score	-0.001265 (rank : 374)
Query Neighborhood Hits	325	Target Neighborhood Hits	739	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

KLF13_MOUSE
θ value	1.81305 (rank : 199)	NC score	-0.001585 (rank : 375)
Query Neighborhood Hits	325	Target Neighborhood Hits	757	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

NHRF2_MOUSE
θ value	1.81305 (rank : 200)	NC score	0.350078 (rank : 69)
Query Neighborhood Hits	325	Target Neighborhood Hits	194	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PABP2_MOUSE
θ value	1.81305 (rank : 201)	NC score	0.028538 (rank : 278)
Query Neighborhood Hits	325	Target Neighborhood Hits	214	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PDLI5_MOUSE
θ value	1.81305 (rank : 202)	NC score	0.094669 (rank : 182)
Query Neighborhood Hits	325	Target Neighborhood Hits	287	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

RU17_HUMAN
θ value	1.81305 (rank : 203)	NC score	0.017376 (rank : 315)
Query Neighborhood Hits	325	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

SGCE_HUMAN
θ value	1.81305 (rank : 204)	NC score	0.031396 (rank : 274)
Query Neighborhood Hits	325	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O43556	Gene names	SGCE, ESG
Domain Architecture
Description	Epsilon-sarcoglycan precursor (Epsilon-SG).

AN32E_MOUSE
θ value	2.36792 (rank : 205)	NC score	0.033190 (rank : 268)
Query Neighborhood Hits	325	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

CO3A1_HUMAN
θ value	2.36792 (rank : 206)	NC score	0.038253 (rank : 251)
Query Neighborhood Hits	325	Target Neighborhood Hits	452	Shared Neighborhood Hits	47
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO8A1_MOUSE
θ value	2.36792 (rank : 207)	NC score	0.026700 (rank : 282)
Query Neighborhood Hits	325	Target Neighborhood Hits	251	Shared Neighborhood Hits	34
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

DVL1_MOUSE
θ value	2.36792 (rank : 208)	NC score	0.224736 (rank : 125)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	105
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

FHOD1_MOUSE
θ value	2.36792 (rank : 209)	NC score	0.018354 (rank : 312)
Query Neighborhood Hits	325	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GDF5_MOUSE
θ value	2.36792 (rank : 210)	NC score	0.006077 (rank : 352)
Query Neighborhood Hits	325	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

IRX5_HUMAN
θ value	2.36792 (rank : 211)	NC score	0.013105 (rank : 328)
Query Neighborhood Hits	325	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

MYST4_HUMAN
θ value	2.36792 (rank : 212)	NC score	0.020085 (rank : 307)
Query Neighborhood Hits	325	Target Neighborhood Hits	671	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PININ_MOUSE
θ value	2.36792 (rank : 213)	NC score	0.025321 (rank : 288)
Query Neighborhood Hits	325	Target Neighborhood Hits	777	Shared Neighborhood Hits	44
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PSMD3_HUMAN
θ value	2.36792 (rank : 214)	NC score	0.019069 (rank : 309)
Query Neighborhood Hits	325	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O43242, Q96EI2, Q9BQA4	Gene names	PSMD3
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit S3) (Proteasome subunit p58).

RAB3I_HUMAN
θ value	2.36792 (rank : 215)	NC score	0.018529 (rank : 311)
Query Neighborhood Hits	325	Target Neighborhood Hits	270	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

RBM25_HUMAN
θ value	2.36792 (rank : 216)	NC score	0.022742 (rank : 298)
Query Neighborhood Hits	325	Target Neighborhood Hits	682	Shared Neighborhood Hits	31
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TM16H_MOUSE
θ value	2.36792 (rank : 217)	NC score	0.016474 (rank : 318)
Query Neighborhood Hits	325	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PB70, Q69ZE4	Gene names	Tmem16h, Kiaa1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TX1B3_HUMAN
θ value	2.36792 (rank : 218)	NC score	0.355447 (rank : 65)
Query Neighborhood Hits	325	Target Neighborhood Hits	161	Shared Neighborhood Hits	126
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	2.36792 (rank : 219)	NC score	0.350726 (rank : 68)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	123
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

ZO1_HUMAN
θ value	2.36792 (rank : 220)	NC score	0.304658 (rank : 94)
Query Neighborhood Hits	325	Target Neighborhood Hits	474	Shared Neighborhood Hits	147
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ADDB_MOUSE
θ value	3.0926 (rank : 221)	NC score	0.032617 (rank : 270)
Query Neighborhood Hits	325	Target Neighborhood Hits	574	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ATBF1_MOUSE
θ value	3.0926 (rank : 222)	NC score	0.009215 (rank : 343)
Query Neighborhood Hits	325	Target Neighborhood Hits	1841	Shared Neighborhood Hits	64
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CB013_HUMAN
θ value	3.0926 (rank : 223)	NC score	0.046674 (rank : 235)
Query Neighborhood Hits	325	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IW19, Q53P47, Q53PB9, Q53QU0	Gene names	C2orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13.

CDX1_HUMAN
θ value	3.0926 (rank : 224)	NC score	0.002636 (rank : 363)
Query Neighborhood Hits	325	Target Neighborhood Hits	382	Shared Neighborhood Hits	10
SwissProt Accessions	P47902, Q4VAU4, Q9NYK8	Gene names	CDX1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

CO2A1_MOUSE
θ value	3.0926 (rank : 225)	NC score	0.037796 (rank : 256)
Query Neighborhood Hits	325	Target Neighborhood Hits	483	Shared Neighborhood Hits	47
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO8A1_HUMAN
θ value	3.0926 (rank : 226)	NC score	0.026498 (rank : 283)
Query Neighborhood Hits	325	Target Neighborhood Hits	288	Shared Neighborhood Hits	38
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

CTRO_MOUSE
θ value	3.0926 (rank : 227)	NC score	0.011815 (rank : 330)
Query Neighborhood Hits	325	Target Neighborhood Hits	2344	Shared Neighborhood Hits	64
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DAXX_MOUSE
θ value	3.0926 (rank : 228)	NC score	0.024529 (rank : 291)
Query Neighborhood Hits	325	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DMN_HUMAN
θ value	3.0926 (rank : 229)	NC score	0.023226 (rank : 296)
Query Neighborhood Hits	325	Target Neighborhood Hits	690	Shared Neighborhood Hits	46
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

GIPC1_MOUSE
θ value	3.0926 (rank : 230)	NC score	0.172583 (rank : 141)
Query Neighborhood Hits	325	Target Neighborhood Hits	92	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

JIP2_MOUSE
θ value	3.0926 (rank : 231)	NC score	0.064602 (rank : 209)
Query Neighborhood Hits	325	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

KCNB1_HUMAN
θ value	3.0926 (rank : 232)	NC score	0.003978 (rank : 359)
Query Neighborhood Hits	325	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

LEO1_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.041182 (rank : 241)
Query Neighborhood Hits	325	Target Neighborhood Hits	958	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MARCS_MOUSE
θ value	3.0926 (rank : 234)	NC score	0.032803 (rank : 269)
Query Neighborhood Hits	325	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MAST4_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.051228 (rank : 224)
Query Neighborhood Hits	325	Target Neighborhood Hits	1804	Shared Neighborhood Hits	166
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MINT_MOUSE
θ value	3.0926 (rank : 236)	NC score	0.023472 (rank : 294)
Query Neighborhood Hits	325	Target Neighborhood Hits	1514	Shared Neighborhood Hits	67
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MY18A_MOUSE
θ value	3.0926 (rank : 237)	NC score	0.057873 (rank : 215)
Query Neighborhood Hits	325	Target Neighborhood Hits	1989	Shared Neighborhood Hits	153
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH14_HUMAN
θ value	3.0926 (rank : 238)	NC score	0.010552 (rank : 335)
Query Neighborhood Hits	325	Target Neighborhood Hits	995	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NFM_HUMAN
θ value	3.0926 (rank : 239)	NC score	0.017577 (rank : 314)
Query Neighborhood Hits	325	Target Neighborhood Hits	1328	Shared Neighborhood Hits	56
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PDZ11_HUMAN
θ value	3.0926 (rank : 240)	NC score	0.330572 (rank : 80)
Query Neighborhood Hits	325	Target Neighborhood Hits	160	Shared Neighborhood Hits	115
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SGCE_MOUSE
θ value	3.0926 (rank : 241)	NC score	0.022669 (rank : 299)
Query Neighborhood Hits	325	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	O70258	Gene names	Sgce
Domain Architecture
Description	Epsilon-sarcoglycan precursor (Epsilon-SG).

ZCPW1_MOUSE
θ value	3.0926 (rank : 242)	NC score	0.024171 (rank : 293)
Query Neighborhood Hits	325	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

AFF4_MOUSE
θ value	4.03905 (rank : 243)	NC score	0.024271 (rank : 292)
Query Neighborhood Hits	325	Target Neighborhood Hits	581	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AN13B_HUMAN
θ value	4.03905 (rank : 244)	NC score	0.009027 (rank : 344)
Query Neighborhood Hits	325	Target Neighborhood Hits	265	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CO5A1_MOUSE
θ value	4.03905 (rank : 245)	NC score	0.040067 (rank : 243)
Query Neighborhood Hits	325	Target Neighborhood Hits	419	Shared Neighborhood Hits	46
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

COBA1_HUMAN
θ value	4.03905 (rank : 246)	NC score	0.039948 (rank : 246)
Query Neighborhood Hits	325	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	4.03905 (rank : 247)	NC score	0.039560 (rank : 247)
Query Neighborhood Hits	325	Target Neighborhood Hits	487	Shared Neighborhood Hits	56
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

DVL2_HUMAN
θ value	4.03905 (rank : 248)	NC score	0.201999 (rank : 133)
Query Neighborhood Hits	325	Target Neighborhood Hits	223	Shared Neighborhood Hits	105
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	4.03905 (rank : 249)	NC score	0.202767 (rank : 132)
Query Neighborhood Hits	325	Target Neighborhood Hits	233	Shared Neighborhood Hits	111
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

HXA5_MOUSE
θ value	4.03905 (rank : 250)	NC score	0.000585 (rank : 370)
Query Neighborhood Hits	325	Target Neighborhood Hits	338	Shared Neighborhood Hits	7
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

LEO1_MOUSE
θ value	4.03905 (rank : 251)	NC score	0.038975 (rank : 250)
Query Neighborhood Hits	325	Target Neighborhood Hits	946	Shared Neighborhood Hits	70
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MYO15_HUMAN
θ value	4.03905 (rank : 252)	NC score	0.007341 (rank : 348)
Query Neighborhood Hits	325	Target Neighborhood Hits	671	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PGCB_HUMAN
θ value	4.03905 (rank : 253)	NC score	0.004928 (rank : 356)
Query Neighborhood Hits	325	Target Neighborhood Hits	478	Shared Neighborhood Hits	17
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

RIMS1_HUMAN
θ value	4.03905 (rank : 254)	NC score	0.151768 (rank : 150)
Query Neighborhood Hits	325	Target Neighborhood Hits	437	Shared Neighborhood Hits	125
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RPGR1_MOUSE
θ value	4.03905 (rank : 255)	NC score	0.025348 (rank : 287)
Query Neighborhood Hits	325	Target Neighborhood Hits	713	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SASH1_MOUSE
θ value	4.03905 (rank : 256)	NC score	0.022551 (rank : 300)
Query Neighborhood Hits	325	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SF3A1_MOUSE
θ value	4.03905 (rank : 257)	NC score	0.013564 (rank : 327)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

TLX2_HUMAN
θ value	4.03905 (rank : 258)	NC score	0.001044 (rank : 368)
Query Neighborhood Hits	325	Target Neighborhood Hits	352	Shared Neighborhood Hits	12
SwissProt Accessions	O43763, Q9UQ48	Gene names	TLX2, HOX11L1, NCX
Domain Architecture
Description	T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein).

ADDA_HUMAN
θ value	5.27518 (rank : 259)	NC score	0.014393 (rank : 323)
Query Neighborhood Hits	325	Target Neighborhood Hits	108	Shared Neighborhood Hits	12
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

CO2A1_HUMAN
θ value	5.27518 (rank : 260)	NC score	0.037956 (rank : 253)
Query Neighborhood Hits	325	Target Neighborhood Hits	486	Shared Neighborhood Hits	51
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO5A1_HUMAN
θ value	5.27518 (rank : 261)	NC score	0.039433 (rank : 248)
Query Neighborhood Hits	325	Target Neighborhood Hits	434	Shared Neighborhood Hits	47
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CS015_HUMAN
θ value	5.27518 (rank : 262)	NC score	0.017027 (rank : 317)
Query Neighborhood Hits	325	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZRH7, Q659E1	Gene names	C19orf15
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf15 precursor.

CTRO_HUMAN
θ value	5.27518 (rank : 263)	NC score	0.011190 (rank : 332)
Query Neighborhood Hits	325	Target Neighborhood Hits	2092	Shared Neighborhood Hits	56
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DVL3_HUMAN
θ value	5.27518 (rank : 264)	NC score	0.215050 (rank : 127)
Query Neighborhood Hits	325	Target Neighborhood Hits	194	Shared Neighborhood Hits	105
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	5.27518 (rank : 265)	NC score	0.213964 (rank : 128)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	104
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

MY18A_HUMAN
θ value	5.27518 (rank : 266)	NC score	0.052929 (rank : 221)
Query Neighborhood Hits	325	Target Neighborhood Hits	1929	Shared Neighborhood Hits	162
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NOLC1_HUMAN
θ value	5.27518 (rank : 267)	NC score	0.037556 (rank : 257)
Query Neighborhood Hits	325	Target Neighborhood Hits	452	Shared Neighborhood Hits	43
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PDLI5_HUMAN
θ value	5.27518 (rank : 268)	NC score	0.096825 (rank : 176)
Query Neighborhood Hits	325	Target Neighborhood Hits	322	Shared Neighborhood Hits	93
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PTN4_HUMAN
θ value	5.27518 (rank : 269)	NC score	0.069393 (rank : 200)
Query Neighborhood Hits	325	Target Neighborhood Hits	303	Shared Neighborhood Hits	90
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

ZO1_MOUSE
θ value	5.27518 (rank : 270)	NC score	0.309399 (rank : 89)
Query Neighborhood Hits	325	Target Neighborhood Hits	453	Shared Neighborhood Hits	152
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

AN32E_HUMAN
θ value	6.88961 (rank : 271)	NC score	0.029231 (rank : 277)
Query Neighborhood Hits	325	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

ARI1B_HUMAN
θ value	6.88961 (rank : 272)	NC score	0.014937 (rank : 320)
Query Neighborhood Hits	325	Target Neighborhood Hits	567	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ATS19_HUMAN
θ value	6.88961 (rank : 273)	NC score	0.000971 (rank : 369)
Query Neighborhood Hits	325	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

BCOR_MOUSE
θ value	6.88961 (rank : 274)	NC score	0.009653 (rank : 340)
Query Neighborhood Hits	325	Target Neighborhood Hits	521	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BLM_MOUSE
θ value	6.88961 (rank : 275)	NC score	0.004384 (rank : 357)
Query Neighborhood Hits	325	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

CAC1C_MOUSE
θ value	6.88961 (rank : 276)	NC score	0.006852 (rank : 350)
Query Neighborhood Hits	325	Target Neighborhood Hits	130	Shared Neighborhood Hits	12
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CO1A1_MOUSE
θ value	6.88961 (rank : 277)	NC score	0.037453 (rank : 258)
Query Neighborhood Hits	325	Target Neighborhood Hits	457	Shared Neighborhood Hits	52
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COBA2_MOUSE
θ value	6.88961 (rank : 278)	NC score	0.035681 (rank : 264)
Query Neighborhood Hits	325	Target Neighborhood Hits	501	Shared Neighborhood Hits	51
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COHA1_HUMAN
θ value	6.88961 (rank : 279)	NC score	0.031624 (rank : 273)
Query Neighborhood Hits	325	Target Neighborhood Hits	400	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COHA1_MOUSE
θ value	6.88961 (rank : 280)	NC score	0.032077 (rank : 272)
Query Neighborhood Hits	325	Target Neighborhood Hits	414	Shared Neighborhood Hits	49
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

GIPC1_HUMAN
θ value	6.88961 (rank : 281)	NC score	0.152249 (rank : 149)
Query Neighborhood Hits	325	Target Neighborhood Hits	91	Shared Neighborhood Hits	80
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

GIPC2_MOUSE
θ value	6.88961 (rank : 282)	NC score	0.100999 (rank : 173)
Query Neighborhood Hits	325	Target Neighborhood Hits	71	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GOGA2_HUMAN
θ value	6.88961 (rank : 283)	NC score	0.014173 (rank : 324)
Query Neighborhood Hits	325	Target Neighborhood Hits	856	Shared Neighborhood Hits	26
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

PDZ11_MOUSE
θ value	6.88961 (rank : 284)	NC score	0.319006 (rank : 83)
Query Neighborhood Hits	325	Target Neighborhood Hits	154	Shared Neighborhood Hits	108
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

RPGF1_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.010865 (rank : 334)
Query Neighborhood Hits	325	Target Neighborhood Hits	262	Shared Neighborhood Hits	23
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SIPA1_HUMAN
θ value	6.88961 (rank : 286)	NC score	0.080237 (rank : 192)
Query Neighborhood Hits	325	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SNTB1_HUMAN
θ value	6.88961 (rank : 287)	NC score	0.275163 (rank : 109)
Query Neighborhood Hits	325	Target Neighborhood Hits	157	Shared Neighborhood Hits	124
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	6.88961 (rank : 288)	NC score	0.273878 (rank : 111)
Query Neighborhood Hits	325	Target Neighborhood Hits	160	Shared Neighborhood Hits	123
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

TPM4_MOUSE
θ value	6.88961 (rank : 289)	NC score	0.018059 (rank : 313)
Query Neighborhood Hits	325	Target Neighborhood Hits	703	Shared Neighborhood Hits	34
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

WDR33_HUMAN
θ value	6.88961 (rank : 290)	NC score	0.010397 (rank : 336)
Query Neighborhood Hits	325	Target Neighborhood Hits	638	Shared Neighborhood Hits	40
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

WRIP1_MOUSE
θ value	6.88961 (rank : 291)	NC score	0.010077 (rank : 338)
Query Neighborhood Hits	325	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

ZMY15_HUMAN
θ value	6.88961 (rank : 292)	NC score	0.015993 (rank : 319)
Query Neighborhood Hits	325	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

AATK_MOUSE
θ value	8.99809 (rank : 293)	NC score	-0.001087 (rank : 372)
Query Neighborhood Hits	325	Target Neighborhood Hits	942	Shared Neighborhood Hits	34
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

AFF1_MOUSE
θ value	8.99809 (rank : 294)	NC score	0.020408 (rank : 306)
Query Neighborhood Hits	325	Target Neighborhood Hits	351	Shared Neighborhood Hits	24
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ANXA7_MOUSE
θ value	8.99809 (rank : 295)	NC score	0.005773 (rank : 354)
Query Neighborhood Hits	325	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

CAC1C_HUMAN
θ value	8.99809 (rank : 296)	NC score	0.006119 (rank : 351)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CF150_HUMAN
θ value	8.99809 (rank : 297)	NC score	0.023203 (rank : 297)
Query Neighborhood Hits	325	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

CGRE1_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.048626 (rank : 227)
Query Neighborhood Hits	325	Target Neighborhood Hits	354	Shared Neighborhood Hits	53
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CO1A1_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.037919 (rank : 254)
Query Neighborhood Hits	325	Target Neighborhood Hits	475	Shared Neighborhood Hits	51
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COAA1_HUMAN
θ value	8.99809 (rank : 300)	NC score	0.025190 (rank : 289)
Query Neighborhood Hits	325	Target Neighborhood Hits	316	Shared Neighborhood Hits	41
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COBA2_HUMAN
θ value	8.99809 (rank : 301)	NC score	0.036713 (rank : 260)
Query Neighborhood Hits	325	Target Neighborhood Hits	408	Shared Neighborhood Hits	48
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CT011_HUMAN
θ value	8.99809 (rank : 302)	NC score	0.014032 (rank : 326)
Query Neighborhood Hits	325	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWU2, Q8N5M5	Gene names	C20orf11
Domain Architecture
Description	Protein C20orf11 (Two-hybrid associated protein 1 with RanBPM) (Twa1).

CT011_MOUSE
θ value	8.99809 (rank : 303)	NC score	0.014043 (rank : 325)
Query Neighborhood Hits	325	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7M1	Gene names
Domain Architecture
Description	Protein C20orf11 homolog (Two-hybrid associated protein 1 with RanBPM) (Twa1).

CTCF_MOUSE
θ value	8.99809 (rank : 304)	NC score	-0.004848 (rank : 378)
Query Neighborhood Hits	325	Target Neighborhood Hits	796	Shared Neighborhood Hits	17
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

DAXX_HUMAN
θ value	8.99809 (rank : 305)	NC score	0.026758 (rank : 280)
Query Neighborhood Hits	325	Target Neighborhood Hits	207	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

G3BP_MOUSE
θ value	8.99809 (rank : 306)	NC score	0.008298 (rank : 346)
Query Neighborhood Hits	325	Target Neighborhood Hits	209	Shared Neighborhood Hits	12
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

INVO_HUMAN
θ value	8.99809 (rank : 307)	NC score	0.013077 (rank : 329)
Query Neighborhood Hits	325	Target Neighborhood Hits	636	Shared Neighborhood Hits	29
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

K0256_MOUSE
θ value	8.99809 (rank : 308)	NC score	0.009960 (rank : 339)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

K1543_MOUSE
θ value	8.99809 (rank : 309)	NC score	0.021430 (rank : 302)
Query Neighborhood Hits	325	Target Neighborhood Hits	497	Shared Neighborhood Hits	33
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LRCH1_HUMAN
θ value	8.99809 (rank : 310)	NC score	0.008288 (rank : 347)
Query Neighborhood Hits	325	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

MASTL_MOUSE
θ value	8.99809 (rank : 311)	NC score	0.005275 (rank : 355)
Query Neighborhood Hits	325	Target Neighborhood Hits	862	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MUCDL_MOUSE
θ value	8.99809 (rank : 312)	NC score	0.006954 (rank : 349)
Query Neighborhood Hits	325	Target Neighborhood Hits	461	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYT1_HUMAN
θ value	8.99809 (rank : 313)	NC score	0.009444 (rank : 342)
Query Neighborhood Hits	325	Target Neighborhood Hits	475	Shared Neighborhood Hits	28
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NBEA_HUMAN
θ value	8.99809 (rank : 314)	NC score	0.003283 (rank : 361)
Query Neighborhood Hits	325	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

PELP1_MOUSE
θ value	8.99809 (rank : 315)	NC score	0.031084 (rank : 275)
Query Neighborhood Hits	325	Target Neighborhood Hits	709	Shared Neighborhood Hits	57
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SOX12_HUMAN
θ value	8.99809 (rank : 316)	NC score	0.002159 (rank : 364)
Query Neighborhood Hits	325	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SPTB1_HUMAN
θ value	8.99809 (rank : 317)	NC score	0.003058 (rank : 362)
Query Neighborhood Hits	325	Target Neighborhood Hits	541	Shared Neighborhood Hits	19
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SYNJ1_MOUSE
θ value	8.99809 (rank : 318)	NC score	0.010270 (rank : 337)
Query Neighborhood Hits	325	Target Neighborhood Hits	516	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TF7L1_HUMAN
θ value	8.99809 (rank : 319)	NC score	0.003912 (rank : 360)
Query Neighborhood Hits	325	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TIAM1_HUMAN
θ value	8.99809 (rank : 320)	NC score	0.056674 (rank : 217)
Query Neighborhood Hits	325	Target Neighborhood Hits	225	Shared Neighborhood Hits	59
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TOR2X_HUMAN
θ value	8.99809 (rank : 321)	NC score	0.005858 (rank : 353)
Query Neighborhood Hits	325	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N2E6	Gene names	TOR2A
Domain Architecture	No domain graphic available
Description	Prosalusin precursor (Torsin-2A) (Torsin family 2 member A) [Contains: Salusin-alpha; Salusin-beta].

VGF_HUMAN
θ value	8.99809 (rank : 322)	NC score	0.020612 (rank : 305)
Query Neighborhood Hits	325	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

ZBT17_MOUSE
θ value	8.99809 (rank : 323)	NC score	-0.004714 (rank : 377)
Query Neighborhood Hits	325	Target Neighborhood Hits	940	Shared Neighborhood Hits	32
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).

ZN592_HUMAN
θ value	8.99809 (rank : 324)	NC score	-0.000863 (rank : 371)
Query Neighborhood Hits	325	Target Neighborhood Hits	762	Shared Neighborhood Hits	19
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

ZN592_MOUSE
θ value	8.99809 (rank : 325)	NC score	-0.001108 (rank : 373)
Query Neighborhood Hits	325	Target Neighborhood Hits	768	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

APXL_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.130620 (rank : 157)
Query Neighborhood Hits	325	Target Neighborhood Hits	553	Shared Neighborhood Hits	102
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CNKR2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.096765 (rank : 177)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.096852 (rank : 175)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CRK_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.061677 (rank : 212)
Query Neighborhood Hits	325	Target Neighborhood Hits	308	Shared Neighborhood Hits	34
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.061676 (rank : 213)
Query Neighborhood Hits	325	Target Neighborhood Hits	314	Shared Neighborhood Hits	34
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GIPC3_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.096596 (rank : 179)
Query Neighborhood Hits	325	Target Neighborhood Hits	52	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.094791 (rank : 180)
Query Neighborhood Hits	325	Target Neighborhood Hits	53	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

GRASP_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.188453 (rank : 137)
Query Neighborhood Hits	325	Target Neighborhood Hits	147	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.185028 (rank : 138)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

IL16_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.312850 (rank : 86)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	121
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

KGUA_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.228265 (rank : 122)
Query Neighborhood Hits	325	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.228882 (rank : 120)
Query Neighborhood Hits	325	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LAP2_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.100077 (rank : 174)
Query Neighborhood Hits	325	Target Neighborhood Hits	499	Shared Neighborhood Hits	98
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.094241 (rank : 183)
Query Neighborhood Hits	325	Target Neighborhood Hits	482	Shared Neighborhood Hits	97
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LDB3_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.082545 (rank : 190)
Query Neighborhood Hits	325	Target Neighborhood Hits	497	Shared Neighborhood Hits	84
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.077554 (rank : 194)
Query Neighborhood Hits	325	Target Neighborhood Hits	510	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LMO7_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.055210 (rank : 218)
Query Neighborhood Hits	325	Target Neighborhood Hits	507	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LRRC7_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.108386 (rank : 170)
Query Neighborhood Hits	325	Target Neighborhood Hits	423	Shared Neighborhood Hits	99
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.107550 (rank : 171)
Query Neighborhood Hits	325	Target Neighborhood Hits	416	Shared Neighborhood Hits	97
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

OGFR_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.053614 (rank : 220)
Query Neighborhood Hits	325	Target Neighborhood Hits	584	Shared Neighborhood Hits	77
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PDLI1_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.084203 (rank : 188)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	73
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.089311 (rank : 185)
Query Neighborhood Hits	325	Target Neighborhood Hits	213	Shared Neighborhood Hits	77
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI2_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.162144 (rank : 146)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	96
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI2_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.140859 (rank : 155)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI3_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.096643 (rank : 178)
Query Neighborhood Hits	325	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.084151 (rank : 189)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	72
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.088471 (rank : 186)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	78
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.090147 (rank : 184)
Query Neighborhood Hits	325	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI7_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.075197 (rank : 196)
Query Neighborhood Hits	325	Target Neighborhood Hits	547	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDLI7_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.069841 (rank : 199)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	75
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD6_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.094670 (rank : 181)
Query Neighborhood Hits	325	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PDZD8_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.068435 (rank : 203)
Query Neighborhood Hits	325	Target Neighborhood Hits	185	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PDZK4_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.189329 (rank : 136)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	108
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.190101 (rank : 135)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PRAX_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.050666 (rank : 225)
Query Neighborhood Hits	325	Target Neighborhood Hits	215	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.058864 (rank : 214)
Query Neighborhood Hits	325	Target Neighborhood Hits	199	Shared Neighborhood Hits	51
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PSCBP_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.166706 (rank : 143)
Query Neighborhood Hits	325	Target Neighborhood Hits	123	Shared Neighborhood Hits	91
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PSCBP_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.180442 (rank : 139)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	92
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PTN3_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.062563 (rank : 211)
Query Neighborhood Hits	325	Target Neighborhood Hits	258	Shared Neighborhood Hits	85
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

RGS3_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.063871 (rank : 210)
Query Neighborhood Hits	325	Target Neighborhood Hits	1375	Shared Neighborhood Hits	142
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RHPN1_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.165222 (rank : 144)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	97
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RPGF2_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.150547 (rank : 151)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

RPGF6_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.168373 (rank : 142)
Query Neighborhood Hits	325	Target Neighborhood Hits	266	Shared Neighborhood Hits	125
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SHC2_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.077396 (rank : 195)
Query Neighborhood Hits	325	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.068485 (rank : 202)
Query Neighborhood Hits	325	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SIPA1_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.068513 (rank : 201)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	21
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SNTA1_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.286644 (rank : 103)
Query Neighborhood Hits	325	Target Neighborhood Hits	186	Shared Neighborhood Hits	143
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.283875 (rank : 107)
Query Neighborhood Hits	325	Target Neighborhood Hits	170	Shared Neighborhood Hits	136
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SYJ2B_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.368999 (rank : 61)
Query Neighborhood Hits	325	Target Neighborhood Hits	162	Shared Neighborhood Hits	127
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

SYNP2_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.084853 (rank : 187)
Query Neighborhood Hits	325	Target Neighborhood Hits	323	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYNP2_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.115045 (rank : 168)
Query Neighborhood Hits	325	Target Neighborhood Hits	252	Shared Neighborhood Hits	90
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SYP2L_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.147865 (rank : 152)
Query Neighborhood Hits	325	Target Neighborhood Hits	400	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYP2L_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.105006 (rank : 172)
Query Neighborhood Hits	325	Target Neighborhood Hits	289	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

Hits sorted by NC score

APBA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	325	Target Neighborhood Hits	325	Shared Neighborhood Hits	325
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

APBA2_HUMAN
NC score	0.956569 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	163
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
NC score	0.955398 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	325	Target Neighborhood Hits	219	Shared Neighborhood Hits	159
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
NC score	0.938851 (rank : 4)	θ value	3.62588e-142 (rank : 4)
Query Neighborhood Hits	325	Target Neighborhood Hits	201	Shared Neighborhood Hits	143
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
NC score	0.934011 (rank : 5)	θ value	1.12976e-135 (rank : 5)
Query Neighborhood Hits	325	Target Neighborhood Hits	174	Shared Neighborhood Hits	141
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SDCB2_MOUSE
NC score	0.533066 (rank : 6)	θ value	3.52202e-12 (rank : 6)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	101
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB1_HUMAN
NC score	0.527186 (rank : 7)	θ value	1.25267e-09 (rank : 8)
Query Neighborhood Hits	325	Target Neighborhood Hits	150	Shared Neighborhood Hits	121
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB2_HUMAN
NC score	0.526462 (rank : 8)	θ value	3.89403e-11 (rank : 7)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	98
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB1_MOUSE
NC score	0.516582 (rank : 9)	θ value	6.21693e-09 (rank : 10)
Query Neighborhood Hits	325	Target Neighborhood Hits	144	Shared Neighborhood Hits	113
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

INADL_HUMAN
NC score	0.495356 (rank : 10)	θ value	6.21693e-09 (rank : 9)
Query Neighborhood Hits	325	Target Neighborhood Hits	260	Shared Neighborhood Hits	156
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

MPDZ_HUMAN
NC score	0.492603 (rank : 11)	θ value	1.80886e-08 (rank : 11)
Query Neighborhood Hits	325	Target Neighborhood Hits	261	Shared Neighborhood Hits	159
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

GRIP1_MOUSE
NC score	0.491915 (rank : 12)	θ value	3.41135e-07 (rank : 16)
Query Neighborhood Hits	325	Target Neighborhood Hits	241	Shared Neighborhood Hits	152
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_HUMAN
NC score	0.491588 (rank : 13)	θ value	1.53129e-07 (rank : 12)
Query Neighborhood Hits	325	Target Neighborhood Hits	231	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP2_HUMAN
NC score	0.484613 (rank : 14)	θ value	1.69304e-06 (rank : 18)
Query Neighborhood Hits	325	Target Neighborhood Hits	256	Shared Neighborhood Hits	153
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

INADL_MOUSE
NC score	0.483220 (rank : 15)	θ value	4.45536e-07 (rank : 17)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	155
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

MPDZ_MOUSE
NC score	0.482143 (rank : 16)	θ value	1.99992e-07 (rank : 14)
Query Neighborhood Hits	325	Target Neighborhood Hits	298	Shared Neighborhood Hits	160
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

DLG3_MOUSE
NC score	0.472351 (rank : 17)	θ value	2.21117e-06 (rank : 20)
Query Neighborhood Hits	325	Target Neighborhood Hits	274	Shared Neighborhood Hits	147
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.470733 (rank : 18)	θ value	2.21117e-06 (rank : 19)
Query Neighborhood Hits	325	Target Neighborhood Hits	269	Shared Neighborhood Hits	147
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

LIN7C_HUMAN
NC score	0.470131 (rank : 19)	θ value	0.000270298 (rank : 32)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.470131 (rank : 20)	θ value	0.000270298 (rank : 33)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	150
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

DLG2_HUMAN
NC score	0.467330 (rank : 21)	θ value	2.61198e-07 (rank : 15)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	150
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG4_MOUSE
NC score	0.467064 (rank : 22)	θ value	2.88788e-06 (rank : 22)
Query Neighborhood Hits	325	Target Neighborhood Hits	282	Shared Neighborhood Hits	147
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.466525 (rank : 23)	θ value	2.88788e-06 (rank : 21)
Query Neighborhood Hits	325	Target Neighborhood Hits	286	Shared Neighborhood Hits	145
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_MOUSE
NC score	0.466468 (rank : 24)	θ value	1.99992e-07 (rank : 13)
Query Neighborhood Hits	325	Target Neighborhood Hits	271	Shared Neighborhood Hits	149
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LIN7B_HUMAN
NC score	0.462699 (rank : 25)	θ value	0.000786445 (rank : 44)
Query Neighborhood Hits	325	Target Neighborhood Hits	200	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.460746 (rank : 26)	θ value	0.00102713 (rank : 51)
Query Neighborhood Hits	325	Target Neighborhood Hits	200	Shared Neighborhood Hits	150
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

DLG1_HUMAN
NC score	0.458297 (rank : 27)	θ value	4.92598e-06 (rank : 23)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	142
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

LIN7A_MOUSE
NC score	0.458073 (rank : 28)	θ value	0.00175202 (rank : 64)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	148
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7A_HUMAN
NC score	0.457912 (rank : 29)	θ value	0.00175202 (rank : 63)
Query Neighborhood Hits	325	Target Neighborhood Hits	193	Shared Neighborhood Hits	148
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

DLG1_MOUSE
NC score	0.456428 (rank : 30)	θ value	1.87187e-05 (rank : 25)
Query Neighborhood Hits	325	Target Neighborhood Hits	285	Shared Neighborhood Hits	143
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

PAR3L_HUMAN
NC score	0.449692 (rank : 31)	θ value	0.000461057 (rank : 37)
Query Neighborhood Hits	325	Target Neighborhood Hits	297	Shared Neighborhood Hits	141
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

USH1C_HUMAN
NC score	0.445736 (rank : 32)	θ value	0.00175202 (rank : 66)
Query Neighborhood Hits	325	Target Neighborhood Hits	327	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

PDZD7_HUMAN
NC score	0.443793 (rank : 33)	θ value	0.00228821 (rank : 68)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	136
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

MAGI1_MOUSE
NC score	0.431783 (rank : 34)	θ value	1.87187e-05 (rank : 26)
Query Neighborhood Hits	325	Target Neighborhood Hits	403	Shared Neighborhood Hits	167
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
NC score	0.428321 (rank : 35)	θ value	4.1701e-05 (rank : 29)
Query Neighborhood Hits	325	Target Neighborhood Hits	388	Shared Neighborhood Hits	170
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

USH1C_MOUSE
NC score	0.427369 (rank : 36)	θ value	0.000602161 (rank : 43)
Query Neighborhood Hits	325	Target Neighborhood Hits	557	Shared Neighborhood Hits	162
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PARD3_HUMAN
NC score	0.427038 (rank : 37)	θ value	0.00665767 (rank : 76)
Query Neighborhood Hits	325	Target Neighborhood Hits	312	Shared Neighborhood Hits	157
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
NC score	0.426574 (rank : 38)	θ value	0.0148317 (rank : 87)
Query Neighborhood Hits	325	Target Neighborhood Hits	290	Shared Neighborhood Hits	150
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

MAGI2_HUMAN
NC score	0.422477 (rank : 39)	θ value	2.44474e-05 (rank : 27)
Query Neighborhood Hits	325	Target Neighborhood Hits	373	Shared Neighborhood Hits	159
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
NC score	0.421086 (rank : 40)	θ value	2.44474e-05 (rank : 28)
Query Neighborhood Hits	325	Target Neighborhood Hits	370	Shared Neighborhood Hits	154
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

WHRN_HUMAN
NC score	0.418170 (rank : 41)	θ value	0.00665767 (rank : 78)
Query Neighborhood Hits	325	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

PDZD1_MOUSE
NC score	0.415152 (rank : 42)	θ value	0.00390308 (rank : 73)
Query Neighborhood Hits	325	Target Neighborhood Hits	191	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

WHRN_MOUSE
NC score	0.414138 (rank : 43)	θ value	0.00665767 (rank : 79)
Query Neighborhood Hits	325	Target Neighborhood Hits	412	Shared Neighborhood Hits	159
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

MPP4_HUMAN
NC score	0.414061 (rank : 44)	θ value	0.000158464 (rank : 31)
Query Neighborhood Hits	325	Target Neighborhood Hits	205	Shared Neighborhood Hits	130
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

GOPC_MOUSE
NC score	0.410015 (rank : 45)	θ value	0.00869519 (rank : 82)
Query Neighborhood Hits	325	Target Neighborhood Hits	323	Shared Neighborhood Hits	136
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PDZD2_HUMAN
NC score	0.405377 (rank : 46)	θ value	0.0148317 (rank : 88)
Query Neighborhood Hits	325	Target Neighborhood Hits	772	Shared Neighborhood Hits	173
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

GOPC_HUMAN
NC score	0.404207 (rank : 47)	θ value	0.00869519 (rank : 81)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	136
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

LNX1_HUMAN
NC score	0.404195 (rank : 48)	θ value	0.000786445 (rank : 45)
Query Neighborhood Hits	325	Target Neighborhood Hits	379	Shared Neighborhood Hits	140
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
NC score	0.403137 (rank : 49)	θ value	0.00134147 (rank : 56)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	147
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MPP3_MOUSE
NC score	0.399382 (rank : 50)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	126
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP3_HUMAN
NC score	0.397462 (rank : 51)	θ value	0.000786445 (rank : 46)
Query Neighborhood Hits	325	Target Neighborhood Hits	171	Shared Neighborhood Hits	126
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

LNX2_HUMAN
NC score	0.395083 (rank : 52)	θ value	0.0431538 (rank : 103)
Query Neighborhood Hits	325	Target Neighborhood Hits	389	Shared Neighborhood Hits	147
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
NC score	0.392187 (rank : 53)	θ value	0.0113563 (rank : 83)
Query Neighborhood Hits	325	Target Neighborhood Hits	407	Shared Neighborhood Hits	148
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MPP4_MOUSE
NC score	0.387906 (rank : 54)	θ value	0.00035302 (rank : 35)
Query Neighborhood Hits	325	Target Neighborhood Hits	188	Shared Neighborhood Hits	121
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP5_HUMAN
NC score	0.386778 (rank : 55)	θ value	0.00102713 (rank : 52)
Query Neighborhood Hits	325	Target Neighborhood Hits	231	Shared Neighborhood Hits	124
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.385832 (rank : 56)	θ value	0.000270298 (rank : 34)
Query Neighborhood Hits	325	Target Neighborhood Hits	226	Shared Neighborhood Hits	124
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PDZD3_HUMAN
NC score	0.381444 (rank : 57)	θ value	0.0736092 (rank : 112)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	135
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD1_HUMAN
NC score	0.380770 (rank : 58)	θ value	0.47712 (rank : 156)
Query Neighborhood Hits	325	Target Neighborhood Hits	190	Shared Neighborhood Hits	128
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

EM55_HUMAN
NC score	0.370345 (rank : 59)	θ value	0.00102713 (rank : 50)
Query Neighborhood Hits	325	Target Neighborhood Hits	228	Shared Neighborhood Hits	118
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.369491 (rank : 60)	θ value	0.00175202 (rank : 62)
Query Neighborhood Hits	325	Target Neighborhood Hits	221	Shared Neighborhood Hits	117
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

SYJ2B_HUMAN
NC score	0.368999 (rank : 61)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	325	Target Neighborhood Hits	162	Shared Neighborhood Hits	127
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

K1849_HUMAN
NC score	0.368727 (rank : 62)	θ value	0.00390308 (rank : 72)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	126
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

NHERF_MOUSE
NC score	0.362349 (rank : 63)	θ value	0.279714 (rank : 138)
Query Neighborhood Hits	325	Target Neighborhood Hits	195	Shared Neighborhood Hits	130
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
NC score	0.359138 (rank : 64)	θ value	1.38821 (rank : 187)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	135
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

TX1B3_HUMAN
NC score	0.355447 (rank : 65)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	325	Target Neighborhood Hits	161	Shared Neighborhood Hits	126
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

PDZD3_MOUSE
NC score	0.353984 (rank : 66)	θ value	0.279714 (rank : 142)
Query Neighborhood Hits	325	Target Neighborhood Hits	171	Shared Neighborhood Hits	127
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

NHERF_HUMAN
NC score	0.351250 (rank : 67)	θ value	0.279714 (rank : 137)
Query Neighborhood Hits	325	Target Neighborhood Hits	190	Shared Neighborhood Hits	127
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

TX1B3_MOUSE
NC score	0.350726 (rank : 68)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	123
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

NHRF2_MOUSE
NC score	0.350078 (rank : 69)	θ value	1.81305 (rank : 200)
Query Neighborhood Hits	325	Target Neighborhood Hits	194	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

K1849_MOUSE
NC score	0.348501 (rank : 70)	θ value	0.0148317 (rank : 86)
Query Neighborhood Hits	325	Target Neighborhood Hits	335	Shared Neighborhood Hits	154
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZO3_MOUSE
NC score	0.348031 (rank : 71)	θ value	0.279714 (rank : 145)
Query Neighborhood Hits	325	Target Neighborhood Hits	224	Shared Neighborhood Hits	142
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_HUMAN
NC score	0.345289 (rank : 72)	θ value	0.47712 (rank : 158)
Query Neighborhood Hits	325	Target Neighborhood Hits	219	Shared Neighborhood Hits	138
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

IL16_HUMAN
NC score	0.339960 (rank : 73)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	325	Target Neighborhood Hits	207	Shared Neighborhood Hits	124
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTG2_HUMAN
NC score	0.339246 (rank : 74)	θ value	0.0563607 (rank : 110)
Query Neighborhood Hits	325	Target Neighborhood Hits	191	Shared Neighborhood Hits	146
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

MPP6_MOUSE
NC score	0.338225 (rank : 75)	θ value	0.00102713 (rank : 53)
Query Neighborhood Hits	325	Target Neighborhood Hits	187	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

SNTB2_MOUSE
NC score	0.337900 (rank : 76)	θ value	0.0148317 (rank : 90)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	132
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

MPP6_HUMAN
NC score	0.337239 (rank : 77)	θ value	0.00134147 (rank : 57)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP2_MOUSE
NC score	0.335243 (rank : 78)	θ value	0.0193708 (rank : 93)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

SNTB2_HUMAN
NC score	0.333254 (rank : 79)	θ value	0.0330416 (rank : 101)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	131
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

PDZ11_HUMAN
NC score	0.330572 (rank : 80)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	325	Target Neighborhood Hits	160	Shared Neighborhood Hits	115
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

MPP2_HUMAN
NC score	0.330120 (rank : 81)	θ value	0.0193708 (rank : 92)
Query Neighborhood Hits	325	Target Neighborhood Hits	173	Shared Neighborhood Hits	92
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

AFAD_HUMAN
NC score	0.322948 (rank : 82)	θ value	0.0148317 (rank : 84)
Query Neighborhood Hits	325	Target Neighborhood Hits	689	Shared Neighborhood Hits	145
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PDZ11_MOUSE
NC score	0.319006 (rank : 83)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	325	Target Neighborhood Hits	154	Shared Neighborhood Hits	108
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PICK1_MOUSE
NC score	0.316292 (rank : 84)	θ value	0.0736092 (rank : 114)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	111
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
NC score	0.316209 (rank : 85)	θ value	0.0736092 (rank : 113)
Query Neighborhood Hits	325	Target Neighborhood Hits	132	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

IL16_MOUSE
NC score	0.312850 (rank : 86)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	121
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

NEB1_HUMAN
NC score	0.311871 (rank : 87)	θ value	0.00228821 (rank : 67)
Query Neighborhood Hits	325	Target Neighborhood Hits	829	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SNTG1_MOUSE
NC score	0.310036 (rank : 88)	θ value	0.62314 (rank : 162)
Query Neighborhood Hits	325	Target Neighborhood Hits	179	Shared Neighborhood Hits	136
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ZO1_MOUSE
NC score	0.309399 (rank : 89)	θ value	5.27518 (rank : 270)
Query Neighborhood Hits	325	Target Neighborhood Hits	453	Shared Neighborhood Hits	152
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SNTG1_HUMAN
NC score	0.308361 (rank : 90)	θ value	0.813845 (rank : 170)
Query Neighborhood Hits	325	Target Neighborhood Hits	181	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ZO2_MOUSE
NC score	0.306875 (rank : 91)	θ value	0.125558 (rank : 127)
Query Neighborhood Hits	325	Target Neighborhood Hits	296	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

SNTG2_MOUSE
NC score	0.305351 (rank : 92)	θ value	0.47712 (rank : 157)
Query Neighborhood Hits	325	Target Neighborhood Hits	176	Shared Neighborhood Hits	136
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

ZO2_HUMAN
NC score	0.305333 (rank : 93)	θ value	0.0961366 (rank : 119)
Query Neighborhood Hits	325	Target Neighborhood Hits	289	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO1_HUMAN
NC score	0.304658 (rank : 94)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	325	Target Neighborhood Hits	474	Shared Neighborhood Hits	147
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

NEB2_HUMAN
NC score	0.302198 (rank : 95)	θ value	0.000602161 (rank : 38)
Query Neighborhood Hits	325	Target Neighborhood Hits	883	Shared Neighborhood Hits	138
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

DLG5_HUMAN
NC score	0.300145 (rank : 96)	θ value	0.00134147 (rank : 55)
Query Neighborhood Hits	325	Target Neighborhood Hits	1088	Shared Neighborhood Hits	160
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PAR6A_MOUSE
NC score	0.299349 (rank : 97)	θ value	0.125558 (rank : 123)
Query Neighborhood Hits	325	Target Neighborhood Hits	115	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

NEB2_MOUSE
NC score	0.298481 (rank : 98)	θ value	0.000602161 (rank : 39)
Query Neighborhood Hits	325	Target Neighborhood Hits	889	Shared Neighborhood Hits	138
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PAR6A_HUMAN
NC score	0.298227 (rank : 99)	θ value	0.125558 (rank : 122)
Query Neighborhood Hits	325	Target Neighborhood Hits	119	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PZRN4_HUMAN
NC score	0.295750 (rank : 100)	θ value	0.125558 (rank : 126)
Query Neighborhood Hits	325	Target Neighborhood Hits	438	Shared Neighborhood Hits	133
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

LAP4_HUMAN
NC score	0.293546 (rank : 101)	θ value	0.000461057 (rank : 36)
Query Neighborhood Hits	325	Target Neighborhood Hits	608	Shared Neighborhood Hits	168
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
NC score	0.286970 (rank : 102)	θ value	0.00665767 (rank : 75)
Query Neighborhood Hits	325	Target Neighborhood Hits	590	Shared Neighborhood Hits	170
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

SNTA1_HUMAN
NC score	0.286644 (rank : 103)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	325	Target Neighborhood Hits	186	Shared Neighborhood Hits	143
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

PZRN3_MOUSE
NC score	0.286251 (rank : 104)	θ value	0.813845 (rank : 167)
Query Neighborhood Hits	325	Target Neighborhood Hits	447	Shared Neighborhood Hits	131
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PAR6G_HUMAN
NC score	0.284989 (rank : 105)	θ value	0.125558 (rank : 124)
Query Neighborhood Hits	325	Target Neighborhood Hits	159	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
NC score	0.284243 (rank : 106)	θ value	0.125558 (rank : 125)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

SNTA1_MOUSE
NC score	0.283875 (rank : 107)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	325	Target Neighborhood Hits	170	Shared Neighborhood Hits	136
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PZRN3_HUMAN
NC score	0.282022 (rank : 108)	θ value	1.06291 (rank : 178)
Query Neighborhood Hits	325	Target Neighborhood Hits	461	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SNTB1_HUMAN
NC score	0.275163 (rank : 109)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	325	Target Neighborhood Hits	157	Shared Neighborhood Hits	124
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

PAR6B_MOUSE
NC score	0.273953 (rank : 110)	θ value	1.06291 (rank : 177)
Query Neighborhood Hits	325	Target Neighborhood Hits	128	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

SNTB1_MOUSE
NC score	0.273878 (rank : 111)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	325	Target Neighborhood Hits	160	Shared Neighborhood Hits	123
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PAR6B_HUMAN
NC score	0.272471 (rank : 112)	θ value	1.06291 (rank : 176)
Query Neighborhood Hits	325	Target Neighborhood Hits	126	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

NOS1_HUMAN
NC score	0.271747 (rank : 113)	θ value	1.09739e-05 (rank : 24)
Query Neighborhood Hits	325	Target Neighborhood Hits	218	Shared Neighborhood Hits	133
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

STXB4_HUMAN
NC score	0.259838 (rank : 114)	θ value	0.00390308 (rank : 74)
Query Neighborhood Hits	325	Target Neighborhood Hits	616	Shared Neighborhood Hits	101
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
NC score	0.259398 (rank : 115)	θ value	0.00298849 (rank : 71)
Query Neighborhood Hits	325	Target Neighborhood Hits	629	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PTN13_HUMAN
NC score	0.254331 (rank : 116)	θ value	0.00298849 (rank : 70)
Query Neighborhood Hits	325	Target Neighborhood Hits	471	Shared Neighborhood Hits	162
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
NC score	0.249026 (rank : 117)	θ value	0.00665767 (rank : 77)
Query Neighborhood Hits	325	Target Neighborhood Hits	426	Shared Neighborhood Hits	156
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

SHAN2_HUMAN
NC score	0.246774 (rank : 118)	θ value	0.0563607 (rank : 108)
Query Neighborhood Hits	325	Target Neighborhood Hits	346	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

NOS1_MOUSE
NC score	0.244487 (rank : 119)	θ value	7.1131e-05 (rank : 30)
Query Neighborhood Hits	325	Target Neighborhood Hits	155	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

KGUA_MOUSE
NC score	0.228882 (rank : 120)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	325	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

DVL1L_HUMAN
NC score	0.228705 (rank : 121)	θ value	0.47712 (rank : 152)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	104
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

KGUA_HUMAN
NC score	0.228265 (rank : 122)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	325	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

DVL1_HUMAN
NC score	0.228177 (rank : 123)	θ value	1.81305 (rank : 197)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	107
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

SHAN2_MOUSE
NC score	0.225851 (rank : 124)	θ value	0.0563607 (rank : 109)
Query Neighborhood Hits	325	Target Neighborhood Hits	446	Shared Neighborhood Hits	115
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

DVL1_MOUSE
NC score	0.224736 (rank : 125)	θ value	2.36792 (rank : 208)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	105
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

ARHGB_HUMAN
NC score	0.219393 (rank : 126)	θ value	0.0563607 (rank : 107)
Query Neighborhood Hits	325	Target Neighborhood Hits	375	Shared Neighborhood Hits	132
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

DVL3_HUMAN
NC score	0.215050 (rank : 127)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	325	Target Neighborhood Hits	194	Shared Neighborhood Hits	105
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
NC score	0.213964 (rank : 128)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	104
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

ARHGC_HUMAN
NC score	0.212307 (rank : 129)	θ value	0.0252991 (rank : 95)
Query Neighborhood Hits	325	Target Neighborhood Hits	351	Shared Neighborhood Hits	124
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.209052 (rank : 130)	θ value	0.0330416 (rank : 98)
Query Neighborhood Hits	325	Target Neighborhood Hits	344	Shared Neighborhood Hits	126
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RGS12_HUMAN
NC score	0.207607 (rank : 131)	θ value	0.0148317 (rank : 89)
Query Neighborhood Hits	325	Target Neighborhood Hits	333	Shared Neighborhood Hits	128
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

DVL2_MOUSE
NC score	0.202767 (rank : 132)	θ value	4.03905 (rank : 249)
Query Neighborhood Hits	325	Target Neighborhood Hits	233	Shared Neighborhood Hits	111
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_HUMAN
NC score	0.201999 (rank : 133)	θ value	4.03905 (rank : 248)
Query Neighborhood Hits	325	Target Neighborhood Hits	223	Shared Neighborhood Hits	105
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

RHPN1_MOUSE
NC score	0.194329 (rank : 134)	θ value	0.62314 (rank : 161)
Query Neighborhood Hits	325	Target Neighborhood Hits	154	Shared Neighborhood Hits	102
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PDZK4_MOUSE
NC score	0.190101 (rank : 135)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_HUMAN
NC score	0.189329 (rank : 136)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	325	Target Neighborhood Hits	165	Shared Neighborhood Hits	108
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

GRASP_HUMAN
NC score	0.188453 (rank : 137)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	325	Target Neighborhood Hits	147	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.185028 (rank : 138)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PSCBP_MOUSE
NC score	0.180442 (rank : 139)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	92
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

SHAN1_HUMAN
NC score	0.178512 (rank : 140)	θ value	0.00175202 (rank : 65)
Query Neighborhood Hits	325	Target Neighborhood Hits	1041	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

GIPC1_MOUSE
NC score	0.172583 (rank : 141)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	325	Target Neighborhood Hits	92	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

RPGF6_HUMAN
NC score	0.168373 (rank : 142)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	325	Target Neighborhood Hits	266	Shared Neighborhood Hits	125
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PSCBP_HUMAN
NC score	0.166706 (rank : 143)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	325	Target Neighborhood Hits	123	Shared Neighborhood Hits	91
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RHPN1_HUMAN
NC score	0.165222 (rank : 144)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	97
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GIPC2_HUMAN
NC score	0.162201 (rank : 145)	θ value	0.279714 (rank : 135)
Query Neighborhood Hits	325	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

PDLI2_HUMAN
NC score	0.162144 (rank : 146)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	96
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

SHC3_HUMAN
NC score	0.159778 (rank : 147)	θ value	0.000602161 (rank : 42)
Query Neighborhood Hits	325	Target Neighborhood Hits	155	Shared Neighborhood Hits	14
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
NC score	0.157216 (rank : 148)	θ value	0.00134147 (rank : 59)
Query Neighborhood Hits	325	Target Neighborhood Hits	151	Shared Neighborhood Hits	15
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

GIPC1_HUMAN
NC score	0.152249 (rank : 149)	θ value	6.88961 (rank : 281)
Query Neighborhood Hits	325	Target Neighborhood Hits	91	Shared Neighborhood Hits	80
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

RIMS1_HUMAN
NC score	0.151768 (rank : 150)	θ value	4.03905 (rank : 254)
Query Neighborhood Hits	325	Target Neighborhood Hits	437	Shared Neighborhood Hits	125
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RPGF2_HUMAN
NC score	0.150547 (rank : 151)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SYP2L_HUMAN
NC score	0.147865 (rank : 152)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	325	Target Neighborhood Hits	400	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SHC1_HUMAN
NC score	0.144317 (rank : 153)	θ value	0.000602161 (rank : 40)
Query Neighborhood Hits	325	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
NC score	0.143008 (rank : 154)	θ value	0.000602161 (rank : 41)
Query Neighborhood Hits	325	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

PDLI2_MOUSE
NC score	0.140859 (rank : 155)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	325	Target Neighborhood Hits	220	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PCLO_MOUSE
NC score	0.134537 (rank : 156)	θ value	0.279714 (rank : 141)
Query Neighborhood Hits	325	Target Neighborhood Hits	2275	Shared Neighborhood Hits	206
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

APXL_HUMAN
NC score	0.130620 (rank : 157)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	325	Target Neighborhood Hits	553	Shared Neighborhood Hits	102
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CSKP_HUMAN
NC score	0.129338 (rank : 158)	θ value	0.00175202 (rank : 60)
Query Neighborhood Hits	325	Target Neighborhood Hits	1022	Shared Neighborhood Hits	120
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
NC score	0.128703 (rank : 159)	θ value	0.00175202 (rank : 61)
Query Neighborhood Hits	325	Target Neighborhood Hits	1027	Shared Neighborhood Hits	120
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

SI1L2_HUMAN
NC score	0.128323 (rank : 160)	θ value	0.0431538 (rank : 105)
Query Neighborhood Hits	325	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
NC score	0.126227 (rank : 161)	θ value	0.0431538 (rank : 106)
Query Neighborhood Hits	325	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
NC score	0.122378 (rank : 162)	θ value	0.0961366 (rank : 118)
Query Neighborhood Hits	325	Target Neighborhood Hits	305	Shared Neighborhood Hits	44
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

RIMS2_HUMAN
NC score	0.122064 (rank : 163)	θ value	0.813845 (rank : 168)
Query Neighborhood Hits	325	Target Neighborhood Hits	342	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SI1L1_HUMAN
NC score	0.121276 (rank : 164)	θ value	0.0736092 (rank : 115)
Query Neighborhood Hits	325	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
NC score	0.120983 (rank : 165)	θ value	0.0736092 (rank : 116)
Query Neighborhood Hits	325	Target Neighborhood Hits	189	Shared Neighborhood Hits	46
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

RIMS2_MOUSE
NC score	0.119461 (rank : 166)	θ value	0.813845 (rank : 169)
Query Neighborhood Hits	325	Target Neighborhood Hits	376	Shared Neighborhood Hits	99
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

JIP1_HUMAN
NC score	0.116486 (rank : 167)	θ value	0.0252991 (rank : 96)
Query Neighborhood Hits	325	Target Neighborhood Hits	271	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

SYNP2_MOUSE
NC score	0.115045 (rank : 168)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	325	Target Neighborhood Hits	252	Shared Neighborhood Hits	90
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

JIP1_MOUSE
NC score	0.111957 (rank : 169)	θ value	0.0431538 (rank : 102)
Query Neighborhood Hits	325	Target Neighborhood Hits	259	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

LRRC7_HUMAN
NC score	0.108386 (rank : 170)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	325	Target Neighborhood Hits	423	Shared Neighborhood Hits	99
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.107550 (rank : 171)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	325	Target Neighborhood Hits	416	Shared Neighborhood Hits	97
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

SYP2L_MOUSE
NC score	0.105006 (rank : 172)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	325	Target Neighborhood Hits	289	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

GIPC2_MOUSE
NC score	0.100999 (rank : 173)	θ value	6.88961 (rank : 282)
Query Neighborhood Hits	325	Target Neighborhood Hits	71	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

LAP2_HUMAN
NC score	0.100077 (rank : 174)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	325	Target Neighborhood Hits	499	Shared Neighborhood Hits	98
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

CNKR2_MOUSE
NC score	0.096852 (rank : 175)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PDLI5_HUMAN
NC score	0.096825 (rank : 176)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	325	Target Neighborhood Hits	322	Shared Neighborhood Hits	93
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

CNKR2_HUMAN
NC score	0.096765 (rank : 177)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PDLI3_HUMAN
NC score	0.096643 (rank : 178)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	325	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

GIPC3_HUMAN
NC score	0.096596 (rank : 179)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	325	Target Neighborhood Hits	52	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
NC score	0.094791 (rank : 180)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	325	Target Neighborhood Hits	53	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

PDZD6_HUMAN
NC score	0.094670 (rank : 181)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	325	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PDLI5_MOUSE
NC score	0.094669 (rank : 182)	θ value	1.81305 (rank : 202)
Query Neighborhood Hits	325	Target Neighborhood Hits	287	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

LAP2_MOUSE
NC score	0.094241 (rank : 183)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	325	Target Neighborhood Hits	482	Shared Neighborhood Hits	97
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDLI4_MOUSE
NC score	0.090147 (rank : 184)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	325	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI1_MOUSE
NC score	0.089311 (rank : 185)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	325	Target Neighborhood Hits	213	Shared Neighborhood Hits	77
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI4_HUMAN
NC score	0.088471 (rank : 186)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	325	Target Neighborhood Hits	245	Shared Neighborhood Hits	78
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

SYNP2_HUMAN
NC score	0.084853 (rank : 187)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	325	Target Neighborhood Hits	323	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PDLI1_HUMAN
NC score	0.084203 (rank : 188)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	325	Target Neighborhood Hits	242	Shared Neighborhood Hits	73
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI3_MOUSE
NC score	0.084151 (rank : 189)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	325	Target Neighborhood Hits	197	Shared Neighborhood Hits	72
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

LDB3_HUMAN
NC score	0.082545 (rank : 190)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	325	Target Neighborhood Hits	497	Shared Neighborhood Hits	84
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

CB013_MOUSE
NC score	0.082264 (rank : 191)	θ value	0.00298849 (rank : 69)
Query Neighborhood Hits	325	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D842, Q8BZL5, Q99LX6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13 homolog.

SIPA1_HUMAN
NC score	0.080237 (rank : 192)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	325	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

JIP2_HUMAN
NC score	0.079113 (rank : 193)	θ value	1.06291 (rank : 174)
Query Neighborhood Hits	325	Target Neighborhood Hits	288	Shared Neighborhood Hits	36
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

LDB3_MOUSE
NC score	0.077554 (rank : 194)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	325	Target Neighborhood Hits	510	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

SHC2_HUMAN
NC score	0.077396 (rank : 195)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	325	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

PDLI7_HUMAN
NC score	0.075197 (rank : 196)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	325	Target Neighborhood Hits	547	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

ANKS1_MOUSE
NC score	0.074191 (rank : 197)	θ value	0.00102713 (rank : 49)
Query Neighborhood Hits	325	Target Neighborhood Hits	453	Shared Neighborhood Hits	25
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

RGS3_MOUSE
NC score	0.073907 (rank : 198)	θ value	0.0431538 (rank : 104)
Query Neighborhood Hits	325	Target Neighborhood Hits	1621	Shared Neighborhood Hits	151
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PDLI7_MOUSE
NC score	0.069841 (rank : 199)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	325	Target Neighborhood Hits	279	Shared Neighborhood Hits	75
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PTN4_HUMAN
NC score	0.069393 (rank : 200)	θ value	5.27518 (rank : 269)
Query Neighborhood Hits	325	Target Neighborhood Hits	303	Shared Neighborhood Hits	90
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

SIPA1_MOUSE
NC score	0.068513 (rank : 201)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	21
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SHC2_MOUSE
NC score	0.068485 (rank : 202)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	325	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

PDZD8_HUMAN
NC score	0.068435 (rank : 203)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	325	Target Neighborhood Hits	185	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

ANKS1_HUMAN
NC score	0.067030 (rank : 204)	θ value	0.00102713 (rank : 48)
Query Neighborhood Hits	325	Target Neighborhood Hits	438	Shared Neighborhood Hits	23
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

RIMB1_HUMAN
NC score	0.067011 (rank : 205)	θ value	0.00134147 (rank : 58)
Query Neighborhood Hits	325	Target Neighborhood Hits	1479	Shared Neighborhood Hits	87
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PREX1_HUMAN
NC score	0.066309 (rank : 206)	θ value	0.0252991 (rank : 97)
Query Neighborhood Hits	325	Target Neighborhood Hits	177	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

BASP_MOUSE
NC score	0.065453 (rank : 207)	θ value	0.365318 (rank : 146)
Query Neighborhood Hits	325	Target Neighborhood Hits	260	Shared Neighborhood Hits	29
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

RP1L1_HUMAN
NC score	0.065012 (rank : 208)	θ value	0.00102713 (rank : 54)
Query Neighborhood Hits	325	Target Neighborhood Hits	1072	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

JIP2_MOUSE
NC score	0.064602 (rank : 209)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	325	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

RGS3_HUMAN
NC score	0.063871 (rank : 210)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	325	Target Neighborhood Hits	1375	Shared Neighborhood Hits	142
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PTN3_HUMAN
NC score	0.062563 (rank : 211)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	325	Target Neighborhood Hits	258	Shared Neighborhood Hits	85
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

CRK_HUMAN
NC score	0.061677 (rank : 212)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	325	Target Neighborhood Hits	308	Shared Neighborhood Hits	34
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
NC score	0.061676 (rank : 213)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	325	Target Neighborhood Hits	314	Shared Neighborhood Hits	34
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

PRAX_MOUSE
NC score	0.058864 (rank : 214)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	325	Target Neighborhood Hits	199	Shared Neighborhood Hits	51
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

MY18A_MOUSE
NC score	0.057873 (rank : 215)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	325	Target Neighborhood Hits	1989	Shared Neighborhood Hits	153
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

FYB_HUMAN
NC score	0.057470 (rank : 216)	θ value	0.0193708 (rank : 91)
Query Neighborhood Hits	325	Target Neighborhood Hits	379	Shared Neighborhood Hits	37
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

TIAM1_HUMAN
NC score	0.056674 (rank : 217)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	325	Target Neighborhood Hits	225	Shared Neighborhood Hits	59
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

LMO7_HUMAN
NC score	0.055210 (rank : 218)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	325	Target Neighborhood Hits	507	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

BASP_HUMAN
NC score	0.054778 (rank : 219)	θ value	0.125558 (rank : 120)
Query Neighborhood Hits	325	Target Neighborhood Hits	321	Shared Neighborhood Hits	26
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

OGFR_MOUSE
NC score	0.053614 (rank : 220)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	325	Target Neighborhood Hits	584	Shared Neighborhood Hits	77
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

MY18A_HUMAN
NC score	0.052929 (rank : 221)	θ value	5.27518 (rank : 266)
Query Neighborhood Hits	325	Target Neighborhood Hits	1929	Shared Neighborhood Hits	162
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MAST3_HUMAN
NC score	0.051759 (rank : 222)	θ value	0.0736092 (rank : 111)
Query Neighborhood Hits	325	Target Neighborhood Hits	1128	Shared Neighborhood Hits	106
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

CTDP1_HUMAN
NC score	0.051360 (rank : 223)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	325	Target Neighborhood Hits	416	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

MAST4_HUMAN
NC score	0.051228 (rank : 224)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	325	Target Neighborhood Hits	1804	Shared Neighborhood Hits	166
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PRAX_HUMAN
NC score	0.050666 (rank : 225)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	325	Target Neighborhood Hits	215	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

IF39_MOUSE
NC score	0.049112 (rank : 226)	θ value	0.0330416 (rank : 99)
Query Neighborhood Hits	325	Target Neighborhood Hits	206	Shared Neighborhood Hits	17
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

CGRE1_HUMAN
NC score	0.048626 (rank : 227)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	325	Target Neighborhood Hits	354	Shared Neighborhood Hits	53
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

MAST1_MOUSE
NC score	0.047843 (rank : 228)	θ value	0.163984 (rank : 128)
Query Neighborhood Hits	325	Target Neighborhood Hits	1123	Shared Neighborhood Hits	114
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SSXT_MOUSE
NC score	0.047335 (rank : 229)	θ value	0.163984 (rank : 129)
Query Neighborhood Hits	325	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

PKHA6_HUMAN
NC score	0.047231 (rank : 230)	θ value	0.0330416 (rank : 100)
Query Neighborhood Hits	325	Target Neighborhood Hits	556	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RIMB1_MOUSE
NC score	0.047153 (rank : 231)	θ value	0.365318 (rank : 149)
Query Neighborhood Hits	325	Target Neighborhood Hits	1376	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MAST2_HUMAN
NC score	0.046830 (rank : 232)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	325	Target Neighborhood Hits	1189	Shared Neighborhood Hits	115
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SRCH_HUMAN
NC score	0.046803 (rank : 233)	θ value	0.279714 (rank : 143)
Query Neighborhood Hits	325	Target Neighborhood Hits	225	Shared Neighborhood Hits	20
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

CTDP1_MOUSE
NC score	0.046787 (rank : 234)	θ value	0.47712 (rank : 151)
Query Neighborhood Hits	325	Target Neighborhood Hits	146	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

CB013_HUMAN
NC score	0.046674 (rank : 235)	θ value	3.0926 (rank : 223)
Query Neighborhood Hits	325	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IW19, Q53P47, Q53PB9, Q53QU0	Gene names	C2orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13.

MAST1_HUMAN
NC score	0.046578 (rank : 236)	θ value	0.365318 (rank : 147)
Query Neighborhood Hits	325	Target Neighborhood Hits	1146	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NFH_MOUSE
NC score	0.046552 (rank : 237)	θ value	1.06291 (rank : 175)
Query Neighborhood Hits	325	Target Neighborhood Hits	2247	Shared Neighborhood Hits	135
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SSXT_HUMAN
NC score	0.045960 (rank : 238)	θ value	0.21417 (rank : 132)
Query Neighborhood Hits	325	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

MAST2_MOUSE
NC score	0.045310 (rank : 239)	θ value	1.38821 (rank : 186)
Query Neighborhood Hits	325	Target Neighborhood Hits	1110	Shared Neighborhood Hits	109
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

AN32B_HUMAN
NC score	0.043150 (rank : 240)	θ value	0.0148317 (rank : 85)
Query Neighborhood Hits	325	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

LEO1_HUMAN
NC score	0.041182 (rank : 241)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	325	Target Neighborhood Hits	958	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LSP1_MOUSE
NC score	0.040072 (rank : 242)	θ value	0.62314 (rank : 160)
Query Neighborhood Hits	325	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

CO5A1_MOUSE
NC score	0.040067 (rank : 243)	θ value	4.03905 (rank : 245)
Query Neighborhood Hits	325	Target Neighborhood Hits	419	Shared Neighborhood Hits	46
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

SVIL_MOUSE
NC score	0.040058 (rank : 244)	θ value	0.0193708 (rank : 94)
Query Neighborhood Hits	325	Target Neighborhood Hits	439	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

CO3A1_MOUSE
NC score	0.039991 (rank : 245)	θ value	1.06291 (rank : 171)
Query Neighborhood Hits	325	Target Neighborhood Hits	466	Shared Neighborhood Hits	45
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COBA1_HUMAN
NC score	0.039948 (rank : 246)	θ value	4.03905 (rank : 246)
Query Neighborhood Hits	325	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
NC score	0.039560 (rank : 247)	θ value	4.03905 (rank : 247)
Query Neighborhood Hits	325	Target Neighborhood Hits	487	Shared Neighborhood Hits	56
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO5A1_HUMAN
NC score	0.039433 (rank : 248)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	325	Target Neighborhood Hits	434	Shared Neighborhood Hits	47
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

TXND2_MOUSE
NC score	0.039411 (rank : 249)	θ value	0.279714 (rank : 144)
Query Neighborhood Hits	325	Target Neighborhood Hits	828	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

LEO1_MOUSE
NC score	0.038975 (rank : 250)	θ value	4.03905 (rank : 251)
Query Neighborhood Hits	325	Target Neighborhood Hits	946	Shared Neighborhood Hits	70
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

CO3A1_HUMAN
NC score	0.038253 (rank : 251)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	325	Target Neighborhood Hits	452	Shared Neighborhood Hits	47
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

PELP1_HUMAN
NC score	0.038008 (rank : 252)	θ value	0.813845 (rank : 166)
Query Neighborhood Hits	325	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CO2A1_HUMAN
NC score	0.037956 (rank : 253)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	325	Target Neighborhood Hits	486	Shared Neighborhood Hits	51
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO1A1_HUMAN
NC score	0.037919 (rank : 254)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	325	Target Neighborhood Hits	475	Shared Neighborhood Hits	51
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

EMID2_HUMAN
NC score	0.037895 (rank : 255)	θ value	0.21417 (rank : 130)
Query Neighborhood Hits	325	Target Neighborhood Hits	226	Shared Neighborhood Hits	33
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

CO2A1_MOUSE
NC score	0.037796 (rank : 256)	θ value	3.0926 (rank : 225)
Query Neighborhood Hits	325	Target Neighborhood Hits	483	Shared Neighborhood Hits	47
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

NOLC1_HUMAN
NC score	0.037556 (rank : 257)	θ value	5.27518 (rank : 267)
Query Neighborhood Hits	325	Target Neighborhood Hits	452	Shared Neighborhood Hits	43
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

CO1A1_MOUSE
NC score	0.037453 (rank : 258)	θ value	6.88961 (rank : 277)
Query Neighborhood Hits	325	Target Neighborhood Hits	457	Shared Neighborhood Hits	52
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

PKHA6_MOUSE
NC score	0.037182 (rank : 259)	θ value	1.38821 (rank : 188)
Query Neighborhood Hits	325	Target Neighborhood Hits	591	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

COBA2_HUMAN
NC score	0.036713 (rank : 260)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	325	Target Neighborhood Hits	408	Shared Neighborhood Hits	48
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

PABP2_HUMAN
NC score	0.036336 (rank : 261)	θ value	0.279714 (rank : 140)
Query Neighborhood Hits	325	Target Neighborhood Hits	212	Shared Neighborhood Hits	12
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

CCDC9_MOUSE
NC score	0.035907 (rank : 262)	θ value	0.813845 (rank : 163)
Query Neighborhood Hits	325	Target Neighborhood Hits	196	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CO7A1_HUMAN
NC score	0.035786 (rank : 263)	θ value	0.125558 (rank : 121)
Query Neighborhood Hits	325	Target Neighborhood Hits	807	Shared Neighborhood Hits	59
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COBA2_MOUSE
NC score	0.035681 (rank : 264)	θ value	6.88961 (rank : 278)
Query Neighborhood Hits	325	Target Neighborhood Hits	501	Shared Neighborhood Hits	51
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

AN32B_MOUSE
NC score	0.034062 (rank : 265)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	325	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

MYRIP_HUMAN
NC score	0.033824 (rank : 266)	θ value	0.21417 (rank : 131)
Query Neighborhood Hits	325	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

CCD55_HUMAN
NC score	0.033790 (rank : 267)	θ value	0.279714 (rank : 134)
Query Neighborhood Hits	325	Target Neighborhood Hits	513	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

AN32E_MOUSE
NC score	0.033190 (rank : 268)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	325	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

MARCS_MOUSE
NC score	0.032803 (rank : 269)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	325	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

ADDB_MOUSE
NC score	0.032617 (rank : 270)	θ value	3.0926 (rank : 221)
Query Neighborhood Hits	325	Target Neighborhood Hits	574	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

CENPB_HUMAN
NC score	0.032184 (rank : 271)	θ value	0.813845 (rank : 164)
Query Neighborhood Hits	325	Target Neighborhood Hits	133	Shared Neighborhood Hits	15
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

COHA1_MOUSE
NC score	0.032077 (rank : 272)	θ value	6.88961 (rank : 280)
Query Neighborhood Hits	325	Target Neighborhood Hits	414	Shared Neighborhood Hits	49
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COHA1_HUMAN
NC score	0.031624 (rank : 273)	θ value	6.88961 (rank : 279)
Query Neighborhood Hits	325	Target Neighborhood Hits	400	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

SGCE_HUMAN
NC score	0.031396 (rank : 274)	θ value	1.81305 (rank : 204)
Query Neighborhood Hits	325	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O43556	Gene names	SGCE, ESG
Domain Architecture
Description	Epsilon-sarcoglycan precursor (Epsilon-SG).

PELP1_MOUSE
NC score	0.031084 (rank : 275)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	325	Target Neighborhood Hits	709	Shared Neighborhood Hits	57
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

GLU2B_HUMAN
NC score	0.029948 (rank : 276)	θ value	0.47712 (rank : 153)
Query Neighborhood Hits	325	Target Neighborhood Hits	377	Shared Neighborhood Hits	19
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

AN32E_HUMAN
NC score	0.029231 (rank : 277)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	325	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

PABP2_MOUSE
NC score	0.028538 (rank : 278)	θ value	1.81305 (rank : 201)
Query Neighborhood Hits	325	Target Neighborhood Hits	214	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

COEA1_HUMAN
NC score	0.027616 (rank : 279)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	325	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

DAXX_HUMAN
NC score	0.026758 (rank : 280)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	325	Target Neighborhood Hits	207	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

TCAL5_MOUSE
NC score	0.026709 (rank : 281)	θ value	1.06291 (rank : 180)
Query Neighborhood Hits	325	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CCT4, Q497R6	Gene names	Tceal5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CO8A1_MOUSE
NC score	0.026700 (rank : 282)	θ value	2.36792 (rank : 207)
Query Neighborhood Hits	325	Target Neighborhood Hits	251	Shared Neighborhood Hits	34
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

CO8A1_HUMAN
NC score	0.026498 (rank : 283)	θ value	3.0926 (rank : 226)
Query Neighborhood Hits	325	Target Neighborhood Hits	288	Shared Neighborhood Hits	38
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

SFTPD_MOUSE
NC score	0.026337 (rank : 284)	θ value	1.38821 (rank : 192)
Query Neighborhood Hits	325	Target Neighborhood Hits	217	Shared Neighborhood Hits	29
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

NFH_HUMAN
NC score	0.026057 (rank : 285)	θ value	0.0961366 (rank : 117)
Query Neighborhood Hits	325	Target Neighborhood Hits	1242	Shared Neighborhood Hits	58
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MYST3_MOUSE
NC score	0.025735 (rank : 286)	θ value	0.47712 (rank : 154)
Query Neighborhood Hits	325	Target Neighborhood Hits	688	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

RPGR1_MOUSE
NC score	0.025348 (rank : 287)	θ value	4.03905 (rank : 255)
Query Neighborhood Hits	325	Target Neighborhood Hits	713	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

PININ_MOUSE
NC score	0.025321 (rank : 288)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	325	Target Neighborhood Hits	777	Shared Neighborhood Hits	44
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

COAA1_HUMAN
NC score	0.025190 (rank : 289)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	325	Target Neighborhood Hits	316	Shared Neighborhood Hits	41
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COEA1_MOUSE
NC score	0.024834 (rank : 290)	θ value	0.62314 (rank : 159)
Query Neighborhood Hits	325	Target Neighborhood Hits	402	Shared Neighborhood Hits	35
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DAXX_MOUSE
NC score	0.024529 (rank : 291)	θ value	3.0926 (rank : 228)
Query Neighborhood Hits	325	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

AFF4_MOUSE
NC score	0.024271 (rank : 292)	θ value	4.03905 (rank : 243)
Query Neighborhood Hits	325	Target Neighborhood Hits	581	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ZCPW1_MOUSE
NC score	0.024171 (rank : 293)	θ value	3.0926 (rank : 242)
Query Neighborhood Hits	325	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

MINT_MOUSE
NC score	0.023472 (rank : 294)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	325	Target Neighborhood Hits	1514	Shared Neighborhood Hits	67
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NALP5_MOUSE
NC score	0.023390 (rank : 295)	θ value	0.47712 (rank : 155)
Query Neighborhood Hits	325	Target Neighborhood Hits	560	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

DMN_HUMAN
NC score	0.023226 (rank : 296)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	325	Target Neighborhood Hits	690	Shared Neighborhood Hits	46
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

CF150_HUMAN
NC score	0.023203 (rank : 297)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	325	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

RBM25_HUMAN
NC score	0.022742 (rank : 298)	θ value	2.36792 (rank : 216)
Query Neighborhood Hits	325	Target Neighborhood Hits	682	Shared Neighborhood Hits	31
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SGCE_MOUSE
NC score	0.022669 (rank : 299)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	325	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	O70258	Gene names	Sgce
Domain Architecture
Description	Epsilon-sarcoglycan precursor (Epsilon-SG).

SASH1_MOUSE
NC score	0.022551 (rank : 300)	θ value	4.03905 (rank : 256)
Query Neighborhood Hits	325	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

RNZ2_MOUSE
NC score	0.021818 (rank : 301)	θ value	1.38821 (rank : 190)
Query Neighborhood Hits	325	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y81, Q99MF0, Q99MF1, Q9CTA2, Q9D1A8, Q9EPZ2	Gene names	Elac2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2).

K1543_MOUSE
NC score	0.021430 (rank : 302)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	325	Target Neighborhood Hits	497	Shared Neighborhood Hits	33
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

RED1_MOUSE
NC score	0.020868 (rank : 303)	θ value	0.365318 (rank : 148)
Query Neighborhood Hits	325	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZS8, Q8K3X1, Q91ZS6, Q91ZS7, Q91ZS9, Q99MU8	Gene names	Adarb1, Adar2, Red1
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

CABL2_MOUSE
NC score	0.020824 (rank : 304)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	325	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

VGF_HUMAN
NC score	0.020612 (rank : 305)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	325	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

AFF1_MOUSE
NC score	0.020408 (rank : 306)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	325	Target Neighborhood Hits	351	Shared Neighborhood Hits	24
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MYST4_HUMAN
NC score	0.020085 (rank : 307)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	325	Target Neighborhood Hits	671	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NFM_MOUSE
NC score	0.019438 (rank : 308)	θ value	0.279714 (rank : 136)
Query Neighborhood Hits	325	Target Neighborhood Hits	1159	Shared Neighborhood Hits	52
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PSMD3_HUMAN
NC score	0.019069 (rank : 309)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	325	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O43242, Q96EI2, Q9BQA4	Gene names	PSMD3
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit S3) (Proteasome subunit p58).

DGLA_HUMAN
NC score	0.018628 (rank : 310)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	325	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4D2, Q6WQJ0	Gene names	NSDDR, C11orf11, KIAA0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

RAB3I_HUMAN
NC score	0.018529 (rank : 311)	θ value	2.36792 (rank : 215)
Query Neighborhood Hits	325	Target Neighborhood Hits	270	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

FHOD1_MOUSE
NC score	0.018354 (rank : 312)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	325	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

TPM4_MOUSE
NC score	0.018059 (rank : 313)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	325	Target Neighborhood Hits	703	Shared Neighborhood Hits	34
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

NFM_HUMAN
NC score	0.017577 (rank : 314)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	325	Target Neighborhood Hits	1328	Shared Neighborhood Hits	56
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RU17_HUMAN
NC score	0.017376 (rank : 315)	θ value	1.81305 (rank : 203)
Query Neighborhood Hits	325	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

FOXD1_HUMAN
NC score	0.017070 (rank : 316)	θ value	0.00869519 (rank : 80)
Query Neighborhood Hits	325	Target Neighborhood Hits	122	Shared Neighborhood Hits	6
SwissProt Accessions	Q16676, Q12949	Gene names	FOXD1, FKHL8, FREAC4
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4).

CS015_HUMAN
NC score	0.017027 (rank : 317)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	325	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZRH7, Q659E1	Gene names	C19orf15
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf15 precursor.

TM16H_MOUSE
NC score	0.016474 (rank : 318)	θ value	2.36792 (rank : 217)
Query Neighborhood Hits	325	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PB70, Q69ZE4	Gene names	Tmem16h, Kiaa1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

ZMY15_HUMAN
NC score	0.015993 (rank : 319)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	325	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

ARI1B_HUMAN
NC score	0.014937 (rank : 320)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	325	Target Neighborhood Hits	567	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CUTL1_HUMAN
NC score	0.014745 (rank : 321)	θ value	1.06291 (rank : 172)
Query Neighborhood Hits	325	Target Neighborhood Hits	1574	Shared Neighborhood Hits	51
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

PRKDC_HUMAN
NC score	0.014443 (rank : 322)	θ value	1.38821 (rank : 189)
Query Neighborhood Hits	325	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

ADDA_HUMAN
NC score	0.014393 (rank : 323)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	325	Target Neighborhood Hits	108	Shared Neighborhood Hits	12
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

GOGA2_HUMAN
NC score	0.014173 (rank : 324)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	325	Target Neighborhood Hits	856	Shared Neighborhood Hits	26
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

CT011_MOUSE
NC score	0.014043 (rank : 325)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	325	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7M1	Gene names
Domain Architecture
Description	Protein C20orf11 homolog (Two-hybrid associated protein 1 with RanBPM) (Twa1).

CT011_HUMAN
NC score	0.014032 (rank : 326)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	325	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWU2, Q8N5M5	Gene names	C20orf11
Domain Architecture
Description	Protein C20orf11 (Two-hybrid associated protein 1 with RanBPM) (Twa1).

SF3A1_MOUSE
NC score	0.013564 (rank : 327)	θ value	4.03905 (rank : 257)
Query Neighborhood Hits	325	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

IRX5_HUMAN
NC score	0.013105 (rank : 328)	θ value	2.36792 (rank : 211)
Query Neighborhood Hits	325	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

INVO_HUMAN
NC score	0.013077 (rank : 329)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	325	Target Neighborhood Hits	636	Shared Neighborhood Hits	29
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

CTRO_MOUSE
NC score	0.011815 (rank : 330)	θ value	3.0926 (rank : 227)
Query Neighborhood Hits	325	Target Neighborhood Hits	2344	Shared Neighborhood Hits	64
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

FOXQ1_HUMAN
NC score	0.011652 (rank : 331)	θ value	1.06291 (rank : 173)
Query Neighborhood Hits	325	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

CTRO_HUMAN
NC score	0.011190 (rank : 332)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	325	Target Neighborhood Hits	2092	Shared Neighborhood Hits	56
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

TITIN_HUMAN
NC score	0.011000 (rank : 333)	θ value	1.38821 (rank : 193)
Query Neighborhood Hits	325	Target Neighborhood Hits	2923	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

RPGF1_HUMAN
NC score	0.010865 (rank : 334)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	325	Target Neighborhood Hits	262	Shared Neighborhood Hits	23
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

MYH14_HUMAN
NC score	0.010552 (rank : 335)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	325	Target Neighborhood Hits	995	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

WDR33_HUMAN
NC score	0.010397 (rank : 336)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	325	Target Neighborhood Hits	638	Shared Neighborhood Hits	40
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

SYNJ1_MOUSE
NC score	0.010270 (rank : 337)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	325	Target Neighborhood Hits	516	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

WRIP1_MOUSE
NC score	0.010077 (rank : 338)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	325	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

K0256_MOUSE
NC score	0.009960 (rank : 339)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	325	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

BCOR_MOUSE
NC score	0.009653 (rank : 340)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	325	Target Neighborhood Hits	521	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ERCC6_HUMAN
NC score	0.009651 (rank : 341)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	325	Target Neighborhood Hits	247	Shared Neighborhood Hits	15
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

MYT1_HUMAN
NC score	0.009444 (rank : 342)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	325	Target Neighborhood Hits	475	Shared Neighborhood Hits	28
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

ATBF1_MOUSE
NC score	0.009215 (rank : 343)	θ value	3.0926 (rank : 222)
Query Neighborhood Hits	325	Target Neighborhood Hits	1841	Shared Neighborhood Hits	64
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

AN13B_HUMAN
NC score	0.009027 (rank : 344)	θ value	4.03905 (rank : 244)
Query Neighborhood Hits	325	Target Neighborhood Hits	265	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

SCN4A_HUMAN
NC score	0.008501 (rank : 345)	θ value	1.06291 (rank : 179)
Query Neighborhood Hits	325	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

G3BP_MOUSE
NC score	0.008298 (rank : 346)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	325	Target Neighborhood Hits	209	Shared Neighborhood Hits	12
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

LRCH1_HUMAN
NC score	0.008288 (rank : 347)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	325	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

MYO15_HUMAN
NC score	0.007341 (rank : 348)	θ value	4.03905 (rank : 252)
Query Neighborhood Hits	325	Target Neighborhood Hits	671	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MUCDL_MOUSE
NC score	0.006954 (rank : 349)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	325	Target Neighborhood Hits	461	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CAC1C_MOUSE
NC score	0.006852 (rank : 350)	θ value	6.88961 (rank : 276)
Query Neighborhood Hits	325	Target Neighborhood Hits	130	Shared Neighborhood Hits	12
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.006119 (rank : 351)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	325	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

GDF5_MOUSE
NC score	0.006077 (rank : 352)	θ value	2.36792 (rank : 210)
Query Neighborhood Hits	325	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

TOR2X_HUMAN
NC score	0.005858 (rank : 353)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	325	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N2E6	Gene names	TOR2A
Domain Architecture	No domain graphic available
Description	Prosalusin precursor (Torsin-2A) (Torsin family 2 member A) [Contains: Salusin-alpha; Salusin-beta].

ANXA7_MOUSE
NC score	0.005773 (rank : 354)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	325	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

MASTL_MOUSE
NC score	0.005275 (rank : 355)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	325	Target Neighborhood Hits	862	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

PGCB_HUMAN
NC score	0.004928 (rank : 356)	θ value	4.03905 (rank : 253)
Query Neighborhood Hits	325	Target Neighborhood Hits	478	Shared Neighborhood Hits	17
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

BLM_MOUSE
NC score	0.004384 (rank : 357)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	325	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

OXSR1_MOUSE
NC score	0.004210 (rank : 358)	θ value	0.279714 (rank : 139)
Query Neighborhood Hits	325	Target Neighborhood Hits	865	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

KCNB1_HUMAN
NC score	0.003978 (rank : 359)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	325	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

TF7L1_HUMAN
NC score	0.003912 (rank : 360)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	325	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

NBEA_HUMAN
NC score	0.003283 (rank : 361)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	325	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

SPTB1_HUMAN
NC score	0.003058 (rank : 362)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	325	Target Neighborhood Hits	541	Shared Neighborhood Hits	19
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

CDX1_HUMAN
NC score	0.002636 (rank : 363)	θ value	3.0926 (rank : 224)
Query Neighborhood Hits	325	Target Neighborhood Hits	382	Shared Neighborhood Hits	10
SwissProt Accessions	P47902, Q4VAU4, Q9NYK8	Gene names	CDX1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

SOX12_HUMAN
NC score	0.002159 (rank : 364)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	325	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

RREB1_HUMAN
NC score	0.002116 (rank : 365)	θ value	1.38821 (rank : 191)
Query Neighborhood Hits	325	Target Neighborhood Hits	879	Shared Neighborhood Hits	29
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

ZN335_HUMAN
NC score	0.001698 (rank : 366)	θ value	0.365318 (rank : 150)
Query Neighborhood Hits	325	Target Neighborhood Hits	973	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

BC11B_MOUSE
NC score	0.001619 (rank : 367)	θ value	0.279714 (rank : 133)
Query Neighborhood Hits	325	Target Neighborhood Hits	767	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

TLX2_HUMAN
NC score	0.001044 (rank : 368)	θ value	4.03905 (rank : 258)
Query Neighborhood Hits	325	Target Neighborhood Hits	352	Shared Neighborhood Hits	12
SwissProt Accessions	O43763, Q9UQ48	Gene names	TLX2, HOX11L1, NCX
Domain Architecture
Description	T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein).

ATS19_HUMAN
NC score	0.000971 (rank : 369)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	325	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

HXA5_MOUSE
NC score	0.000585 (rank : 370)	θ value	4.03905 (rank : 250)
Query Neighborhood Hits	325	Target Neighborhood Hits	338	Shared Neighborhood Hits	7
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

ZN592_HUMAN
NC score	-0.000863 (rank : 371)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	325	Target Neighborhood Hits	762	Shared Neighborhood Hits	19
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

AATK_MOUSE
NC score	-0.001087 (rank : 372)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	325	Target Neighborhood Hits	942	Shared Neighborhood Hits	34
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ZN592_MOUSE
NC score	-0.001108 (rank : 373)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	325	Target Neighborhood Hits	768	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

KLF13_HUMAN
NC score	-0.001265 (rank : 374)	θ value	1.81305 (rank : 198)
Query Neighborhood Hits	325	Target Neighborhood Hits	739	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

KLF13_MOUSE
NC score	-0.001585 (rank : 375)	θ value	1.81305 (rank : 199)
Query Neighborhood Hits	325	Target Neighborhood Hits	757	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

PEG3_HUMAN
NC score	-0.001925 (rank : 376)	θ value	0.813845 (rank : 165)
Query Neighborhood Hits	325	Target Neighborhood Hits	800	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

ZBT17_MOUSE
NC score	-0.004714 (rank : 377)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	325	Target Neighborhood Hits	940	Shared Neighborhood Hits	32
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).

CTCF_MOUSE
NC score	-0.004848 (rank : 378)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	325	Target Neighborhood Hits	796	Shared Neighborhood Hits	17
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).