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Network neighborhood for query Sequence : WHRN_MOUSE

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WHRN_MOUSE
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WHRN_HUMAN
θ value	0 (rank : 1)	NC score	0.973602 (rank : 2)
Query Neighborhood Hits	412	Target Neighborhood Hits	325	Shared Neighborhood Hits	247
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	412	Target Neighborhood Hits	412	Shared Neighborhood Hits	412
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD7_HUMAN
θ value	3.26607e-42 (rank : 3)	NC score	0.894292 (rank : 3)
Query Neighborhood Hits	412	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

USH1C_HUMAN
θ value	4.00176e-32 (rank : 4)	NC score	0.857113 (rank : 4)
Query Neighborhood Hits	412	Target Neighborhood Hits	327	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	1.98606e-31 (rank : 5)	NC score	0.810065 (rank : 5)
Query Neighborhood Hits	412	Target Neighborhood Hits	557	Shared Neighborhood Hits	225
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

DLG1_HUMAN
θ value	6.85773e-16 (rank : 6)	NC score	0.663214 (rank : 34)
Query Neighborhood Hits	412	Target Neighborhood Hits	290	Shared Neighborhood Hits	172
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG4_MOUSE
θ value	6.85773e-16 (rank : 7)	NC score	0.679902 (rank : 28)
Query Neighborhood Hits	412	Target Neighborhood Hits	282	Shared Neighborhood Hits	180
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG1_MOUSE
θ value	8.95645e-16 (rank : 8)	NC score	0.661336 (rank : 36)
Query Neighborhood Hits	412	Target Neighborhood Hits	285	Shared Neighborhood Hits	174
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG4_HUMAN
θ value	1.52774e-15 (rank : 9)	NC score	0.678451 (rank : 29)
Query Neighborhood Hits	412	Target Neighborhood Hits	286	Shared Neighborhood Hits	178
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PZRN3_MOUSE
θ value	3.40345e-15 (rank : 10)	NC score	0.592022 (rank : 68)
Query Neighborhood Hits	412	Target Neighborhood Hits	447	Shared Neighborhood Hits	163
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RPGF6_HUMAN
θ value	3.40345e-15 (rank : 11)	NC score	0.504695 (rank : 75)
Query Neighborhood Hits	412	Target Neighborhood Hits	266	Shared Neighborhood Hits	172
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

DLG3_HUMAN
θ value	7.58209e-15 (rank : 12)	NC score	0.666231 (rank : 33)
Query Neighborhood Hits	412	Target Neighborhood Hits	269	Shared Neighborhood Hits	180
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	7.58209e-15 (rank : 13)	NC score	0.668068 (rank : 31)
Query Neighborhood Hits	412	Target Neighborhood Hits	274	Shared Neighborhood Hits	181
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

LAP4_HUMAN
θ value	6.41864e-14 (rank : 14)	NC score	0.498188 (rank : 76)
Query Neighborhood Hits	412	Target Neighborhood Hits	608	Shared Neighborhood Hits	214
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PZRN3_HUMAN
θ value	1.09485e-13 (rank : 15)	NC score	0.586654 (rank : 69)
Query Neighborhood Hits	412	Target Neighborhood Hits	461	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LAP4_MOUSE
θ value	1.86753e-13 (rank : 16)	NC score	0.491224 (rank : 77)
Query Neighborhood Hits	412	Target Neighborhood Hits	590	Shared Neighborhood Hits	209
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

NHERF_HUMAN
θ value	1.86753e-13 (rank : 17)	NC score	0.707505 (rank : 21)
Query Neighborhood Hits	412	Target Neighborhood Hits	190	Shared Neighborhood Hits	168
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

DLG2_HUMAN
θ value	3.18553e-13 (rank : 18)	NC score	0.655042 (rank : 41)
Query Neighborhood Hits	412	Target Neighborhood Hits	279	Shared Neighborhood Hits	177
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	4.16044e-13 (rank : 19)	NC score	0.654516 (rank : 42)
Query Neighborhood Hits	412	Target Neighborhood Hits	271	Shared Neighborhood Hits	177
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

MAGI1_MOUSE
θ value	5.43371e-13 (rank : 20)	NC score	0.658774 (rank : 38)
Query Neighborhood Hits	412	Target Neighborhood Hits	403	Shared Neighborhood Hits	205
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MPDZ_MOUSE
θ value	5.43371e-13 (rank : 21)	NC score	0.727742 (rank : 16)
Query Neighborhood Hits	412	Target Neighborhood Hits	298	Shared Neighborhood Hits	195
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PDZD1_MOUSE
θ value	3.52202e-12 (rank : 22)	NC score	0.714129 (rank : 19)
Query Neighborhood Hits	412	Target Neighborhood Hits	191	Shared Neighborhood Hits	171
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

RPGF2_HUMAN
θ value	3.52202e-12 (rank : 23)	NC score	0.449374 (rank : 85)
Query Neighborhood Hits	412	Target Neighborhood Hits	242	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

MPDZ_HUMAN
θ value	4.59992e-12 (rank : 24)	NC score	0.724394 (rank : 17)
Query Neighborhood Hits	412	Target Neighborhood Hits	261	Shared Neighborhood Hits	197
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NHRF2_HUMAN
θ value	4.59992e-12 (rank : 25)	NC score	0.707175 (rank : 22)
Query Neighborhood Hits	412	Target Neighborhood Hits	197	Shared Neighborhood Hits	179
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

INADL_MOUSE
θ value	6.00763e-12 (rank : 26)	NC score	0.732048 (rank : 15)
Query Neighborhood Hits	412	Target Neighborhood Hits	290	Shared Neighborhood Hits	200
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

NHERF_MOUSE
θ value	6.00763e-12 (rank : 27)	NC score	0.713562 (rank : 20)
Query Neighborhood Hits	412	Target Neighborhood Hits	195	Shared Neighborhood Hits	167
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_MOUSE
θ value	7.84624e-12 (rank : 28)	NC score	0.700873 (rank : 23)
Query Neighborhood Hits	412	Target Neighborhood Hits	194	Shared Neighborhood Hits	179
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

INADL_HUMAN
θ value	1.74796e-11 (rank : 29)	NC score	0.724348 (rank : 18)
Query Neighborhood Hits	412	Target Neighborhood Hits	260	Shared Neighborhood Hits	188
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

MAGI1_HUMAN
θ value	2.28291e-11 (rank : 30)	NC score	0.659335 (rank : 37)
Query Neighborhood Hits	412	Target Neighborhood Hits	388	Shared Neighborhood Hits	201
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PTN13_MOUSE
θ value	8.67504e-11 (rank : 31)	NC score	0.416783 (rank : 100)
Query Neighborhood Hits	412	Target Neighborhood Hits	426	Shared Neighborhood Hits	190
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PZRN4_HUMAN
θ value	1.133e-10 (rank : 32)	NC score	0.579505 (rank : 70)
Query Neighborhood Hits	412	Target Neighborhood Hits	438	Shared Neighborhood Hits	154
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

LNX1_HUMAN
θ value	1.47974e-10 (rank : 33)	NC score	0.633247 (rank : 55)
Query Neighborhood Hits	412	Target Neighborhood Hits	379	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

ZO3_MOUSE
θ value	2.52405e-10 (rank : 34)	NC score	0.622344 (rank : 59)
Query Neighborhood Hits	412	Target Neighborhood Hits	224	Shared Neighborhood Hits	185
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PDZ11_HUMAN
θ value	3.29651e-10 (rank : 35)	NC score	0.766587 (rank : 6)
Query Neighborhood Hits	412	Target Neighborhood Hits	160	Shared Neighborhood Hits	155
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	3.29651e-10 (rank : 36)	NC score	0.762868 (rank : 7)
Query Neighborhood Hits	412	Target Neighborhood Hits	154	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

GOPC_HUMAN
θ value	5.62301e-10 (rank : 37)	NC score	0.670236 (rank : 30)
Query Neighborhood Hits	412	Target Neighborhood Hits	377	Shared Neighborhood Hits	169
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	5.62301e-10 (rank : 38)	NC score	0.680537 (rank : 27)
Query Neighborhood Hits	412	Target Neighborhood Hits	323	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LNX1_MOUSE
θ value	5.62301e-10 (rank : 39)	NC score	0.643061 (rank : 48)
Query Neighborhood Hits	412	Target Neighborhood Hits	377	Shared Neighborhood Hits	177
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	5.62301e-10 (rank : 40)	NC score	0.640131 (rank : 50)
Query Neighborhood Hits	412	Target Neighborhood Hits	389	Shared Neighborhood Hits	178
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

SNTA1_HUMAN
θ value	9.59137e-10 (rank : 41)	NC score	0.629897 (rank : 57)
Query Neighborhood Hits	412	Target Neighborhood Hits	186	Shared Neighborhood Hits	164
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

LNX2_MOUSE
θ value	2.13673e-09 (rank : 42)	NC score	0.649484 (rank : 46)
Query Neighborhood Hits	412	Target Neighborhood Hits	407	Shared Neighborhood Hits	178
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LIN7B_HUMAN
θ value	2.79066e-09 (rank : 43)	NC score	0.752938 (rank : 8)
Query Neighborhood Hits	412	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

PTN13_HUMAN
θ value	2.79066e-09 (rank : 44)	NC score	0.422000 (rank : 97)
Query Neighborhood Hits	412	Target Neighborhood Hits	471	Shared Neighborhood Hits	193
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

LIN7A_HUMAN
θ value	3.64472e-09 (rank : 45)	NC score	0.749865 (rank : 11)
Query Neighborhood Hits	412	Target Neighborhood Hits	193	Shared Neighborhood Hits	182
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	3.64472e-09 (rank : 46)	NC score	0.750123 (rank : 10)
Query Neighborhood Hits	412	Target Neighborhood Hits	193	Shared Neighborhood Hits	182
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7B_MOUSE
θ value	3.64472e-09 (rank : 47)	NC score	0.750327 (rank : 9)
Query Neighborhood Hits	412	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

PDZD3_HUMAN
θ value	4.76016e-09 (rank : 48)	NC score	0.661959 (rank : 35)
Query Neighborhood Hits	412	Target Neighborhood Hits	180	Shared Neighborhood Hits	164
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

LIN7C_HUMAN
θ value	8.11959e-09 (rank : 49)	NC score	0.747947 (rank : 12)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	184
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	8.11959e-09 (rank : 50)	NC score	0.747947 (rank : 13)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	184
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PDZD2_HUMAN
θ value	1.06045e-08 (rank : 51)	NC score	0.657771 (rank : 39)
Query Neighborhood Hits	412	Target Neighborhood Hits	772	Shared Neighborhood Hits	230
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PAR3L_HUMAN
θ value	1.80886e-08 (rank : 52)	NC score	0.666972 (rank : 32)
Query Neighborhood Hits	412	Target Neighborhood Hits	297	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

SNTA1_MOUSE
θ value	1.80886e-08 (rank : 53)	NC score	0.620230 (rank : 60)
Query Neighborhood Hits	412	Target Neighborhood Hits	170	Shared Neighborhood Hits	158
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

MAGI2_HUMAN
θ value	2.36244e-08 (rank : 54)	NC score	0.635082 (rank : 54)
Query Neighborhood Hits	412	Target Neighborhood Hits	373	Shared Neighborhood Hits	200
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	2.36244e-08 (rank : 55)	NC score	0.632717 (rank : 56)
Query Neighborhood Hits	412	Target Neighborhood Hits	370	Shared Neighborhood Hits	209
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

SNTB1_HUMAN
θ value	5.26297e-08 (rank : 56)	NC score	0.597413 (rank : 66)
Query Neighborhood Hits	412	Target Neighborhood Hits	157	Shared Neighborhood Hits	149
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB2_HUMAN
θ value	6.87365e-08 (rank : 57)	NC score	0.638327 (rank : 52)
Query Neighborhood Hits	412	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	6.87365e-08 (rank : 58)	NC score	0.639351 (rank : 51)
Query Neighborhood Hits	412	Target Neighborhood Hits	181	Shared Neighborhood Hits	161
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

ZO3_HUMAN
θ value	6.87365e-08 (rank : 59)	NC score	0.603813 (rank : 64)
Query Neighborhood Hits	412	Target Neighborhood Hits	219	Shared Neighborhood Hits	174
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PDZD1_HUMAN
θ value	1.53129e-07 (rank : 60)	NC score	0.695483 (rank : 26)
Query Neighborhood Hits	412	Target Neighborhood Hits	190	Shared Neighborhood Hits	170
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PARD3_MOUSE
θ value	1.99992e-07 (rank : 61)	NC score	0.651058 (rank : 43)
Query Neighborhood Hits	412	Target Neighborhood Hits	290	Shared Neighborhood Hits	170
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

SNTB1_MOUSE
θ value	2.61198e-07 (rank : 62)	NC score	0.596107 (rank : 67)
Query Neighborhood Hits	412	Target Neighborhood Hits	160	Shared Neighborhood Hits	148
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTG2_MOUSE
θ value	2.61198e-07 (rank : 63)	NC score	0.617301 (rank : 61)
Query Neighborhood Hits	412	Target Neighborhood Hits	176	Shared Neighborhood Hits	163
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

GRIP1_MOUSE
θ value	5.81887e-07 (rank : 64)	NC score	0.650110 (rank : 44)
Query Neighborhood Hits	412	Target Neighborhood Hits	241	Shared Neighborhood Hits	192
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PARD3_HUMAN
θ value	5.81887e-07 (rank : 65)	NC score	0.648020 (rank : 47)
Query Neighborhood Hits	412	Target Neighborhood Hits	312	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

GRIP1_HUMAN
θ value	9.92553e-07 (rank : 66)	NC score	0.649657 (rank : 45)
Query Neighborhood Hits	412	Target Neighborhood Hits	231	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PDZD3_MOUSE
θ value	9.92553e-07 (rank : 67)	NC score	0.636207 (rank : 53)
Query Neighborhood Hits	412	Target Neighborhood Hits	171	Shared Neighborhood Hits	164
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

ZO2_HUMAN
θ value	9.92553e-07 (rank : 68)	NC score	0.553074 (rank : 72)
Query Neighborhood Hits	412	Target Neighborhood Hits	289	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DLG5_HUMAN
θ value	1.69304e-06 (rank : 69)	NC score	0.428624 (rank : 93)
Query Neighborhood Hits	412	Target Neighborhood Hits	1088	Shared Neighborhood Hits	209
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

SNTG2_HUMAN
θ value	1.69304e-06 (rank : 70)	NC score	0.642462 (rank : 49)
Query Neighborhood Hits	412	Target Neighborhood Hits	191	Shared Neighborhood Hits	175
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

ZO2_MOUSE
θ value	1.69304e-06 (rank : 71)	NC score	0.553496 (rank : 71)
Query Neighborhood Hits	412	Target Neighborhood Hits	296	Shared Neighborhood Hits	181
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ARHGB_HUMAN
θ value	2.21117e-06 (rank : 72)	NC score	0.376299 (rank : 115)
Query Neighborhood Hits	412	Target Neighborhood Hits	375	Shared Neighborhood Hits	180
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

GRIP2_HUMAN
θ value	2.88788e-06 (rank : 73)	NC score	0.655270 (rank : 40)
Query Neighborhood Hits	412	Target Neighborhood Hits	256	Shared Neighborhood Hits	195
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

SNTG1_HUMAN
θ value	3.77169e-06 (rank : 74)	NC score	0.608698 (rank : 63)
Query Neighborhood Hits	412	Target Neighborhood Hits	181	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_MOUSE
θ value	3.77169e-06 (rank : 75)	NC score	0.609691 (rank : 62)
Query Neighborhood Hits	412	Target Neighborhood Hits	179	Shared Neighborhood Hits	166
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SYP2L_HUMAN
θ value	3.77169e-06 (rank : 76)	NC score	0.452664 (rank : 82)
Query Neighborhood Hits	412	Target Neighborhood Hits	400	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ZO1_HUMAN
θ value	3.77169e-06 (rank : 77)	NC score	0.545912 (rank : 74)
Query Neighborhood Hits	412	Target Neighborhood Hits	474	Shared Neighborhood Hits	197
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	3.77169e-06 (rank : 78)	NC score	0.553055 (rank : 73)
Query Neighborhood Hits	412	Target Neighborhood Hits	453	Shared Neighborhood Hits	192
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

PAR6G_HUMAN
θ value	4.92598e-06 (rank : 79)	NC score	0.451158 (rank : 83)
Query Neighborhood Hits	412	Target Neighborhood Hits	159	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

IL16_HUMAN
θ value	6.43352e-06 (rank : 80)	NC score	0.625469 (rank : 58)
Query Neighborhood Hits	412	Target Neighborhood Hits	207	Shared Neighborhood Hits	145
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PAR6B_HUMAN
θ value	1.09739e-05 (rank : 81)	NC score	0.443784 (rank : 89)
Query Neighborhood Hits	412	Target Neighborhood Hits	126	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

RHPN1_HUMAN
θ value	1.09739e-05 (rank : 82)	NC score	0.410537 (rank : 102)
Query Neighborhood Hits	412	Target Neighborhood Hits	158	Shared Neighborhood Hits	133
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RIMS1_HUMAN
θ value	1.09739e-05 (rank : 83)	NC score	0.274470 (rank : 152)
Query Neighborhood Hits	412	Target Neighborhood Hits	437	Shared Neighborhood Hits	138
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

TX1B3_HUMAN
θ value	1.43324e-05 (rank : 84)	NC score	0.698797 (rank : 24)
Query Neighborhood Hits	412	Target Neighborhood Hits	161	Shared Neighborhood Hits	160
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	1.43324e-05 (rank : 85)	NC score	0.696644 (rank : 25)
Query Neighborhood Hits	412	Target Neighborhood Hits	158	Shared Neighborhood Hits	157
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PAR6G_MOUSE
θ value	1.87187e-05 (rank : 86)	NC score	0.444137 (rank : 88)
Query Neighborhood Hits	412	Target Neighborhood Hits	121	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

AFAD_HUMAN
θ value	2.44474e-05 (rank : 87)	NC score	0.449444 (rank : 84)
Query Neighborhood Hits	412	Target Neighborhood Hits	689	Shared Neighborhood Hits	163
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PAR6B_MOUSE
θ value	2.44474e-05 (rank : 88)	NC score	0.441919 (rank : 90)
Query Neighborhood Hits	412	Target Neighborhood Hits	128	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

SHAN1_HUMAN
θ value	3.19293e-05 (rank : 89)	NC score	0.239154 (rank : 165)
Query Neighborhood Hits	412	Target Neighborhood Hits	1041	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PDLI7_MOUSE
θ value	4.1701e-05 (rank : 90)	NC score	0.262423 (rank : 156)
Query Neighborhood Hits	412	Target Neighborhood Hits	279	Shared Neighborhood Hits	108
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SYP2L_MOUSE
θ value	4.1701e-05 (rank : 91)	NC score	0.362316 (rank : 125)
Query Neighborhood Hits	412	Target Neighborhood Hits	289	Shared Neighborhood Hits	124
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

RGS12_HUMAN
θ value	7.1131e-05 (rank : 92)	NC score	0.331810 (rank : 145)
Query Neighborhood Hits	412	Target Neighborhood Hits	333	Shared Neighborhood Hits	151
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SYJ2B_HUMAN
θ value	7.1131e-05 (rank : 93)	NC score	0.744141 (rank : 14)
Query Neighborhood Hits	412	Target Neighborhood Hits	162	Shared Neighborhood Hits	158
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

RHPN1_MOUSE
θ value	0.000121331 (rank : 94)	NC score	0.424399 (rank : 94)
Query Neighborhood Hits	412	Target Neighborhood Hits	154	Shared Neighborhood Hits	139
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

LRRC7_HUMAN
θ value	0.000158464 (rank : 95)	NC score	0.259442 (rank : 157)
Query Neighborhood Hits	412	Target Neighborhood Hits	423	Shared Neighborhood Hits	121
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.000158464 (rank : 96)	NC score	0.258150 (rank : 159)
Query Neighborhood Hits	412	Target Neighborhood Hits	416	Shared Neighborhood Hits	119
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

ARHGC_HUMAN
θ value	0.00020696 (rank : 97)	NC score	0.341646 (rank : 136)
Query Neighborhood Hits	412	Target Neighborhood Hits	351	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LAP2_HUMAN
θ value	0.00020696 (rank : 98)	NC score	0.247173 (rank : 164)
Query Neighborhood Hits	412	Target Neighborhood Hits	499	Shared Neighborhood Hits	117
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PAR6A_HUMAN
θ value	0.00020696 (rank : 99)	NC score	0.421849 (rank : 98)
Query Neighborhood Hits	412	Target Neighborhood Hits	119	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	0.00020696 (rank : 100)	NC score	0.423343 (rank : 95)
Query Neighborhood Hits	412	Target Neighborhood Hits	115	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

LAP2_MOUSE
θ value	0.000270298 (rank : 101)	NC score	0.236597 (rank : 166)
Query Neighborhood Hits	412	Target Neighborhood Hits	482	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PTN4_HUMAN
θ value	0.000270298 (rank : 102)	NC score	0.182647 (rank : 175)
Query Neighborhood Hits	412	Target Neighborhood Hits	303	Shared Neighborhood Hits	128
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

ARHGC_MOUSE
θ value	0.00035302 (rank : 103)	NC score	0.336505 (rank : 142)
Query Neighborhood Hits	412	Target Neighborhood Hits	344	Shared Neighborhood Hits	158
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

EAF1_MOUSE
θ value	0.00035302 (rank : 104)	NC score	0.100639 (rank : 192)
Query Neighborhood Hits	412	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

RGS3_MOUSE
θ value	0.00035302 (rank : 105)	NC score	0.133000 (rank : 181)
Query Neighborhood Hits	412	Target Neighborhood Hits	1621	Shared Neighborhood Hits	207
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

IL16_MOUSE
θ value	0.000461057 (rank : 106)	NC score	0.601600 (rank : 65)
Query Neighborhood Hits	412	Target Neighborhood Hits	189	Shared Neighborhood Hits	141
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

EAF1_HUMAN
θ value	0.000602161 (rank : 107)	NC score	0.097794 (rank : 195)
Query Neighborhood Hits	412	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

K1849_MOUSE
θ value	0.000602161 (rank : 108)	NC score	0.475492 (rank : 79)
Query Neighborhood Hits	412	Target Neighborhood Hits	335	Shared Neighborhood Hits	166
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LDB3_HUMAN
θ value	0.000602161 (rank : 109)	NC score	0.280146 (rank : 150)
Query Neighborhood Hits	412	Target Neighborhood Hits	497	Shared Neighborhood Hits	138
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MAST4_HUMAN
θ value	0.000602161 (rank : 110)	NC score	0.083343 (rank : 210)
Query Neighborhood Hits	412	Target Neighborhood Hits	1804	Shared Neighborhood Hits	217
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PDLI2_MOUSE
θ value	0.000602161 (rank : 111)	NC score	0.449011 (rank : 87)
Query Neighborhood Hits	412	Target Neighborhood Hits	220	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI7_HUMAN
θ value	0.000602161 (rank : 112)	NC score	0.273276 (rank : 153)
Query Neighborhood Hits	412	Target Neighborhood Hits	547	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LMO7_HUMAN
θ value	0.000786445 (rank : 113)	NC score	0.171446 (rank : 177)
Query Neighborhood Hits	412	Target Neighborhood Hits	507	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PICK1_HUMAN
θ value	0.000786445 (rank : 114)	NC score	0.403739 (rank : 106)
Query Neighborhood Hits	412	Target Neighborhood Hits	132	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PTN3_HUMAN
θ value	0.000786445 (rank : 115)	NC score	0.180378 (rank : 176)
Query Neighborhood Hits	412	Target Neighborhood Hits	258	Shared Neighborhood Hits	117
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

APBA2_HUMAN
θ value	0.00102713 (rank : 116)	NC score	0.407106 (rank : 104)
Query Neighborhood Hits	412	Target Neighborhood Hits	220	Shared Neighborhood Hits	154
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.00102713 (rank : 117)	NC score	0.407199 (rank : 103)
Query Neighborhood Hits	412	Target Neighborhood Hits	219	Shared Neighborhood Hits	151
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APXL_HUMAN
θ value	0.00102713 (rank : 118)	NC score	0.362628 (rank : 124)
Query Neighborhood Hits	412	Target Neighborhood Hits	553	Shared Neighborhood Hits	132
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PDZK4_HUMAN
θ value	0.00102713 (rank : 119)	NC score	0.449144 (rank : 86)
Query Neighborhood Hits	412	Target Neighborhood Hits	165	Shared Neighborhood Hits	122
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	0.00102713 (rank : 120)	NC score	0.453400 (rank : 81)
Query Neighborhood Hits	412	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SYNP2_MOUSE
θ value	0.00102713 (rank : 121)	NC score	0.388721 (rank : 109)
Query Neighborhood Hits	412	Target Neighborhood Hits	252	Shared Neighborhood Hits	140
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

MUC1_HUMAN
θ value	0.00134147 (rank : 122)	NC score	0.095747 (rank : 198)
Query Neighborhood Hits	412	Target Neighborhood Hits	975	Shared Neighborhood Hits	139
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PDLI5_MOUSE
θ value	0.00134147 (rank : 123)	NC score	0.268180 (rank : 155)
Query Neighborhood Hits	412	Target Neighborhood Hits	287	Shared Neighborhood Hits	119
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

RIMS2_HUMAN
θ value	0.00134147 (rank : 124)	NC score	0.220831 (rank : 168)
Query Neighborhood Hits	412	Target Neighborhood Hits	342	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.00134147 (rank : 125)	NC score	0.219333 (rank : 169)
Query Neighborhood Hits	412	Target Neighborhood Hits	376	Shared Neighborhood Hits	116
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SHAN2_HUMAN
θ value	0.00134147 (rank : 126)	NC score	0.357335 (rank : 128)
Query Neighborhood Hits	412	Target Neighborhood Hits	346	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

STXB4_HUMAN
θ value	0.00134147 (rank : 127)	NC score	0.341029 (rank : 137)
Query Neighborhood Hits	412	Target Neighborhood Hits	616	Shared Neighborhood Hits	110
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

NEB1_HUMAN
θ value	0.00175202 (rank : 128)	NC score	0.379316 (rank : 114)
Query Neighborhood Hits	412	Target Neighborhood Hits	829	Shared Neighborhood Hits	146
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

STXB4_MOUSE
θ value	0.00175202 (rank : 129)	NC score	0.334230 (rank : 144)
Query Neighborhood Hits	412	Target Neighborhood Hits	629	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

APBA3_MOUSE
θ value	0.00228821 (rank : 130)	NC score	0.387506 (rank : 110)
Query Neighborhood Hits	412	Target Neighborhood Hits	174	Shared Neighborhood Hits	136
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

DVL2_MOUSE
θ value	0.00228821 (rank : 131)	NC score	0.372175 (rank : 119)
Query Neighborhood Hits	412	Target Neighborhood Hits	233	Shared Neighborhood Hits	128
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

MAST3_HUMAN
θ value	0.00228821 (rank : 132)	NC score	0.073424 (rank : 222)
Query Neighborhood Hits	412	Target Neighborhood Hits	1128	Shared Neighborhood Hits	145
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

SHAN2_MOUSE
θ value	0.00228821 (rank : 133)	NC score	0.321419 (rank : 146)
Query Neighborhood Hits	412	Target Neighborhood Hits	446	Shared Neighborhood Hits	140
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

PDLI3_HUMAN
θ value	0.00298849 (rank : 134)	NC score	0.354110 (rank : 129)
Query Neighborhood Hits	412	Target Neighborhood Hits	199	Shared Neighborhood Hits	107
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SDCB1_HUMAN
θ value	0.00298849 (rank : 135)	NC score	0.421443 (rank : 99)
Query Neighborhood Hits	412	Target Neighborhood Hits	150	Shared Neighborhood Hits	144
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

PDLI1_HUMAN
θ value	0.00390308 (rank : 136)	NC score	0.342463 (rank : 134)
Query Neighborhood Hits	412	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

APBA3_HUMAN
θ value	0.00509761 (rank : 137)	NC score	0.396106 (rank : 107)
Query Neighborhood Hits	412	Target Neighborhood Hits	201	Shared Neighborhood Hits	138
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

K1849_HUMAN
θ value	0.00509761 (rank : 138)	NC score	0.480471 (rank : 78)
Query Neighborhood Hits	412	Target Neighborhood Hits	220	Shared Neighborhood Hits	148
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LDB3_MOUSE
θ value	0.00509761 (rank : 139)	NC score	0.279310 (rank : 151)
Query Neighborhood Hits	412	Target Neighborhood Hits	510	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PDLI3_MOUSE
θ value	0.00509761 (rank : 140)	NC score	0.337886 (rank : 139)
Query Neighborhood Hits	412	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI5_HUMAN
θ value	0.00509761 (rank : 141)	NC score	0.268564 (rank : 154)
Query Neighborhood Hits	412	Target Neighborhood Hits	322	Shared Neighborhood Hits	125
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PTN23_MOUSE
θ value	0.00509761 (rank : 142)	NC score	0.078410 (rank : 213)
Query Neighborhood Hits	412	Target Neighborhood Hits	726	Shared Neighborhood Hits	75
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

APBA1_HUMAN
θ value	0.00665767 (rank : 143)	NC score	0.414138 (rank : 101)
Query Neighborhood Hits	412	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

SYNP2_HUMAN
θ value	0.00665767 (rank : 144)	NC score	0.337454 (rank : 140)
Query Neighborhood Hits	412	Target Neighborhood Hits	323	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

GRASP_MOUSE
θ value	0.00869519 (rank : 145)	NC score	0.437492 (rank : 91)
Query Neighborhood Hits	412	Target Neighborhood Hits	131	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

LIMK1_HUMAN
θ value	0.00869519 (rank : 146)	NC score	0.041621 (rank : 327)
Query Neighborhood Hits	412	Target Neighborhood Hits	1005	Shared Neighborhood Hits	83
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
θ value	0.00869519 (rank : 147)	NC score	0.039716 (rank : 332)
Query Neighborhood Hits	412	Target Neighborhood Hits	1008	Shared Neighborhood Hits	81
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

MAST1_HUMAN
θ value	0.00869519 (rank : 148)	NC score	0.071471 (rank : 229)
Query Neighborhood Hits	412	Target Neighborhood Hits	1146	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	0.00869519 (rank : 149)	NC score	0.071877 (rank : 227)
Query Neighborhood Hits	412	Target Neighborhood Hits	1123	Shared Neighborhood Hits	137
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PDLI2_HUMAN
θ value	0.00869519 (rank : 150)	NC score	0.453506 (rank : 80)
Query Neighborhood Hits	412	Target Neighborhood Hits	245	Shared Neighborhood Hits	131
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

SDCB1_MOUSE
θ value	0.00869519 (rank : 151)	NC score	0.422467 (rank : 96)
Query Neighborhood Hits	412	Target Neighborhood Hits	144	Shared Neighborhood Hits	137
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

DVL2_HUMAN
θ value	0.0113563 (rank : 152)	NC score	0.369423 (rank : 120)
Query Neighborhood Hits	412	Target Neighborhood Hits	223	Shared Neighborhood Hits	128
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

MAST2_HUMAN
θ value	0.0113563 (rank : 153)	NC score	0.072072 (rank : 226)
Query Neighborhood Hits	412	Target Neighborhood Hits	1189	Shared Neighborhood Hits	145
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NEB2_HUMAN
θ value	0.0113563 (rank : 154)	NC score	0.352463 (rank : 131)
Query Neighborhood Hits	412	Target Neighborhood Hits	883	Shared Neighborhood Hits	139
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	0.0113563 (rank : 155)	NC score	0.348449 (rank : 132)
Query Neighborhood Hits	412	Target Neighborhood Hits	889	Shared Neighborhood Hits	141
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDLI1_MOUSE
θ value	0.0113563 (rank : 156)	NC score	0.343791 (rank : 133)
Query Neighborhood Hits	412	Target Neighborhood Hits	213	Shared Neighborhood Hits	105
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

DVL3_HUMAN
θ value	0.0148317 (rank : 157)	NC score	0.376163 (rank : 116)
Query Neighborhood Hits	412	Target Neighborhood Hits	194	Shared Neighborhood Hits	120
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

GRASP_HUMAN
θ value	0.0148317 (rank : 158)	NC score	0.436629 (rank : 92)
Query Neighborhood Hits	412	Target Neighborhood Hits	147	Shared Neighborhood Hits	121
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

IRS2_HUMAN
θ value	0.0148317 (rank : 159)	NC score	0.059649 (rank : 266)
Query Neighborhood Hits	412	Target Neighborhood Hits	262	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

TIAM1_HUMAN
θ value	0.0148317 (rank : 160)	NC score	0.130049 (rank : 183)
Query Neighborhood Hits	412	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

BCL9_HUMAN
θ value	0.0193708 (rank : 161)	NC score	0.096140 (rank : 197)
Query Neighborhood Hits	412	Target Neighborhood Hits	1008	Shared Neighborhood Hits	143
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

NOS1_HUMAN
θ value	0.0193708 (rank : 162)	NC score	0.296501 (rank : 149)
Query Neighborhood Hits	412	Target Neighborhood Hits	218	Shared Neighborhood Hits	141
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PDLI4_HUMAN
θ value	0.0193708 (rank : 163)	NC score	0.339157 (rank : 138)
Query Neighborhood Hits	412	Target Neighborhood Hits	245	Shared Neighborhood Hits	119
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	0.0193708 (rank : 164)	NC score	0.342217 (rank : 135)
Query Neighborhood Hits	412	Target Neighborhood Hits	233	Shared Neighborhood Hits	114
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PICK1_MOUSE
θ value	0.0193708 (rank : 165)	NC score	0.392655 (rank : 108)
Query Neighborhood Hits	412	Target Neighborhood Hits	131	Shared Neighborhood Hits	121
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

DVL1_HUMAN
θ value	0.0252991 (rank : 166)	NC score	0.374895 (rank : 117)
Query Neighborhood Hits	412	Target Neighborhood Hits	158	Shared Neighborhood Hits	118
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

MAST2_MOUSE
θ value	0.0252991 (rank : 167)	NC score	0.070462 (rank : 232)
Query Neighborhood Hits	412	Target Neighborhood Hits	1110	Shared Neighborhood Hits	145
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TIAM1_MOUSE
θ value	0.0252991 (rank : 168)	NC score	0.102663 (rank : 190)
Query Neighborhood Hits	412	Target Neighborhood Hits	205	Shared Neighborhood Hits	52
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

NFH_MOUSE
θ value	0.0330416 (rank : 169)	NC score	0.056437 (rank : 283)
Query Neighborhood Hits	412	Target Neighborhood Hits	2247	Shared Neighborhood Hits	159
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRB4S_HUMAN
θ value	0.0330416 (rank : 170)	NC score	0.075957 (rank : 216)
Query Neighborhood Hits	412	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ZN687_HUMAN
θ value	0.0330416 (rank : 171)	NC score	0.015904 (rank : 397)
Query Neighborhood Hits	412	Target Neighborhood Hits	1244	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

MPP5_HUMAN
θ value	0.0431538 (rank : 172)	NC score	0.384022 (rank : 112)
Query Neighborhood Hits	412	Target Neighborhood Hits	231	Shared Neighborhood Hits	132
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.0431538 (rank : 173)	NC score	0.383004 (rank : 113)
Query Neighborhood Hits	412	Target Neighborhood Hits	226	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MUC7_HUMAN
θ value	0.0431538 (rank : 174)	NC score	0.091381 (rank : 202)
Query Neighborhood Hits	412	Target Neighborhood Hits	538	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCOR2_HUMAN
θ value	0.0431538 (rank : 175)	NC score	0.055081 (rank : 286)
Query Neighborhood Hits	412	Target Neighborhood Hits	870	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SDCB2_MOUSE
θ value	0.0431538 (rank : 176)	NC score	0.358054 (rank : 127)
Query Neighborhood Hits	412	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

DVL1L_HUMAN
θ value	0.0563607 (rank : 177)	NC score	0.358608 (rank : 126)
Query Neighborhood Hits	412	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL3_MOUSE
θ value	0.0563607 (rank : 178)	NC score	0.374327 (rank : 118)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	118
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

FA47B_HUMAN
θ value	0.0563607 (rank : 179)	NC score	0.063418 (rank : 253)
Query Neighborhood Hits	412	Target Neighborhood Hits	431	Shared Neighborhood Hits	75
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GA2L3_HUMAN
θ value	0.0563607 (rank : 180)	NC score	0.044812 (rank : 321)
Query Neighborhood Hits	412	Target Neighborhood Hits	189	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

GATA3_HUMAN
θ value	0.0563607 (rank : 181)	NC score	0.033881 (rank : 344)
Query Neighborhood Hits	412	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P23771, Q96J16	Gene names	GATA3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

IF4G3_HUMAN
θ value	0.0563607 (rank : 182)	NC score	0.042660 (rank : 324)
Query Neighborhood Hits	412	Target Neighborhood Hits	247	Shared Neighborhood Hits	30
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PAK4_MOUSE
θ value	0.0563607 (rank : 183)	NC score	0.007154 (rank : 434)
Query Neighborhood Hits	412	Target Neighborhood Hits	1098	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

GATA3_MOUSE
θ value	0.0736092 (rank : 184)	NC score	0.033062 (rank : 347)
Query Neighborhood Hits	412	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	P23772	Gene names	Gata3, Gata-3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

GGN_MOUSE
θ value	0.0736092 (rank : 185)	NC score	0.070042 (rank : 233)
Query Neighborhood Hits	412	Target Neighborhood Hits	311	Shared Neighborhood Hits	46
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

LPP_HUMAN
θ value	0.0736092 (rank : 186)	NC score	0.074402 (rank : 219)
Query Neighborhood Hits	412	Target Neighborhood Hits	775	Shared Neighborhood Hits	118
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAGD4_HUMAN
θ value	0.0736092 (rank : 187)	NC score	0.035359 (rank : 341)
Query Neighborhood Hits	412	Target Neighborhood Hits	338	Shared Neighborhood Hits	47
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

PO6F2_HUMAN
θ value	0.0736092 (rank : 188)	NC score	0.026389 (rank : 367)
Query Neighborhood Hits	412	Target Neighborhood Hits	618	Shared Neighborhood Hits	52
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PREX1_HUMAN
θ value	0.0736092 (rank : 189)	NC score	0.067247 (rank : 241)
Query Neighborhood Hits	412	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PSCBP_MOUSE
θ value	0.0736092 (rank : 190)	NC score	0.404082 (rank : 105)
Query Neighborhood Hits	412	Target Neighborhood Hits	118	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

TCRG1_MOUSE
θ value	0.0736092 (rank : 191)	NC score	0.041190 (rank : 328)
Query Neighborhood Hits	412	Target Neighborhood Hits	947	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

AFF2_MOUSE
θ value	0.0961366 (rank : 192)	NC score	0.040474 (rank : 329)
Query Neighborhood Hits	412	Target Neighborhood Hits	225	Shared Neighborhood Hits	27
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

CDN1C_MOUSE
θ value	0.0961366 (rank : 193)	NC score	0.047042 (rank : 313)
Query Neighborhood Hits	412	Target Neighborhood Hits	161	Shared Neighborhood Hits	18
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CS007_HUMAN
θ value	0.0961366 (rank : 194)	NC score	0.065766 (rank : 243)
Query Neighborhood Hits	412	Target Neighborhood Hits	401	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DVL1_MOUSE
θ value	0.0961366 (rank : 195)	NC score	0.366854 (rank : 122)
Query Neighborhood Hits	412	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GIPC1_MOUSE
θ value	0.0961366 (rank : 196)	NC score	0.228659 (rank : 167)
Query Neighborhood Hits	412	Target Neighborhood Hits	92	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

MPP3_HUMAN
θ value	0.0961366 (rank : 197)	NC score	0.365563 (rank : 123)
Query Neighborhood Hits	412	Target Neighborhood Hits	171	Shared Neighborhood Hits	125
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

PRRT3_HUMAN
θ value	0.0961366 (rank : 198)	NC score	0.097844 (rank : 194)
Query Neighborhood Hits	412	Target Neighborhood Hits	998	Shared Neighborhood Hits	135
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MPP3_MOUSE
θ value	0.125558 (rank : 199)	NC score	0.368162 (rank : 121)
Query Neighborhood Hits	412	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

SYN1_MOUSE
θ value	0.125558 (rank : 200)	NC score	0.059179 (rank : 270)
Query Neighborhood Hits	412	Target Neighborhood Hits	363	Shared Neighborhood Hits	56
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CRTC1_HUMAN
θ value	0.163984 (rank : 201)	NC score	0.052619 (rank : 298)
Query Neighborhood Hits	412	Target Neighborhood Hits	319	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

FOXP4_HUMAN
θ value	0.163984 (rank : 202)	NC score	0.017851 (rank : 389)
Query Neighborhood Hits	412	Target Neighborhood Hits	246	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

GSCR1_HUMAN
θ value	0.163984 (rank : 203)	NC score	0.090703 (rank : 204)
Query Neighborhood Hits	412	Target Neighborhood Hits	674	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PCLO_MOUSE
θ value	0.163984 (rank : 204)	NC score	0.215646 (rank : 171)
Query Neighborhood Hits	412	Target Neighborhood Hits	2275	Shared Neighborhood Hits	269
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDZD8_HUMAN
θ value	0.163984 (rank : 205)	NC score	0.152476 (rank : 178)
Query Neighborhood Hits	412	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

SC24C_HUMAN
θ value	0.163984 (rank : 206)	NC score	0.064208 (rank : 248)
Query Neighborhood Hits	412	Target Neighborhood Hits	662	Shared Neighborhood Hits	98
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

AF10_HUMAN
θ value	0.21417 (rank : 207)	NC score	0.025451 (rank : 370)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

CS007_MOUSE
θ value	0.21417 (rank : 208)	NC score	0.062117 (rank : 259)
Query Neighborhood Hits	412	Target Neighborhood Hits	464	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

GIPC1_HUMAN
θ value	0.21417 (rank : 209)	NC score	0.216395 (rank : 170)
Query Neighborhood Hits	412	Target Neighborhood Hits	91	Shared Neighborhood Hits	81
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

GRIN1_MOUSE
θ value	0.21417 (rank : 210)	NC score	0.055337 (rank : 285)
Query Neighborhood Hits	412	Target Neighborhood Hits	337	Shared Neighborhood Hits	53
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NOS1_MOUSE
θ value	0.21417 (rank : 211)	NC score	0.253185 (rank : 162)
Query Neighborhood Hits	412	Target Neighborhood Hits	155	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PSMD9_HUMAN
θ value	0.21417 (rank : 212)	NC score	0.118949 (rank : 189)
Query Neighborhood Hits	412	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

SYN1_HUMAN
θ value	0.21417 (rank : 213)	NC score	0.062020 (rank : 260)
Query Neighborhood Hits	412	Target Neighborhood Hits	419	Shared Neighborhood Hits	70
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

CAR11_HUMAN
θ value	0.279714 (rank : 214)	NC score	0.091370 (rank : 203)
Query Neighborhood Hits	412	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

IF4G3_MOUSE
θ value	0.279714 (rank : 215)	NC score	0.045168 (rank : 318)
Query Neighborhood Hits	412	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

RTN4_HUMAN
θ value	0.279714 (rank : 216)	NC score	0.036428 (rank : 339)
Query Neighborhood Hits	412	Target Neighborhood Hits	357	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SIPA1_HUMAN
θ value	0.279714 (rank : 217)	NC score	0.063760 (rank : 251)
Query Neighborhood Hits	412	Target Neighborhood Hits	250	Shared Neighborhood Hits	42
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

TCOF_MOUSE
θ value	0.279714 (rank : 218)	NC score	0.074613 (rank : 218)
Query Neighborhood Hits	412	Target Neighborhood Hits	471	Shared Neighborhood Hits	57
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

IFI5_MOUSE
θ value	0.365318 (rank : 219)	NC score	0.020215 (rank : 384)
Query Neighborhood Hits	412	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q08619	Gene names	Ifi205
Domain Architecture
Description	Interferon-activable protein 205 (IFI-205) (D3 protein).

SSBP4_HUMAN
θ value	0.365318 (rank : 220)	NC score	0.049812 (rank : 307)
Query Neighborhood Hits	412	Target Neighborhood Hits	753	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CCNK_MOUSE
θ value	0.47712 (rank : 221)	NC score	0.053541 (rank : 291)
Query Neighborhood Hits	412	Target Neighborhood Hits	350	Shared Neighborhood Hits	52
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD248_HUMAN
θ value	0.47712 (rank : 222)	NC score	0.027834 (rank : 360)
Query Neighborhood Hits	412	Target Neighborhood Hits	679	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FOXN4_HUMAN
θ value	0.47712 (rank : 223)	NC score	0.021934 (rank : 375)
Query Neighborhood Hits	412	Target Neighborhood Hits	248	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

HTRA3_HUMAN
θ value	0.47712 (rank : 224)	NC score	0.124402 (rank : 188)
Query Neighborhood Hits	412	Target Neighborhood Hits	152	Shared Neighborhood Hits	65
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	0.47712 (rank : 225)	NC score	0.133317 (rank : 179)
Query Neighborhood Hits	412	Target Neighborhood Hits	156	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

RGS3_HUMAN
θ value	0.47712 (rank : 226)	NC score	0.127851 (rank : 186)
Query Neighborhood Hits	412	Target Neighborhood Hits	1375	Shared Neighborhood Hits	181
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

T22D4_HUMAN
θ value	0.47712 (rank : 227)	NC score	0.053208 (rank : 295)
Query Neighborhood Hits	412	Target Neighborhood Hits	403	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

CBP_MOUSE
θ value	0.62314 (rank : 228)	NC score	0.061822 (rank : 261)
Query Neighborhood Hits	412	Target Neighborhood Hits	1051	Shared Neighborhood Hits	126
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CI079_HUMAN
θ value	0.62314 (rank : 229)	NC score	0.048148 (rank : 310)
Query Neighborhood Hits	412	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

GIPC3_HUMAN
θ value	0.62314 (rank : 230)	NC score	0.130859 (rank : 182)
Query Neighborhood Hits	412	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	0.62314 (rank : 231)	NC score	0.129423 (rank : 184)
Query Neighborhood Hits	412	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

HXA3_HUMAN
θ value	0.62314 (rank : 232)	NC score	0.013536 (rank : 406)
Query Neighborhood Hits	412	Target Neighborhood Hits	535	Shared Neighborhood Hits	49
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

K1802_HUMAN
θ value	0.62314 (rank : 233)	NC score	0.040360 (rank : 330)
Query Neighborhood Hits	412	Target Neighborhood Hits	1378	Shared Neighborhood Hits	123
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KI13B_HUMAN
θ value	0.62314 (rank : 234)	NC score	0.016272 (rank : 395)
Query Neighborhood Hits	412	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

LCP2_HUMAN
θ value	0.62314 (rank : 235)	NC score	0.047639 (rank : 311)
Query Neighborhood Hits	412	Target Neighborhood Hits	531	Shared Neighborhood Hits	74
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LR37A_HUMAN
θ value	0.62314 (rank : 236)	NC score	0.030640 (rank : 353)
Query Neighborhood Hits	412	Target Neighborhood Hits	720	Shared Neighborhood Hits	66
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

OGFR_HUMAN
θ value	0.62314 (rank : 237)	NC score	0.073811 (rank : 221)
Query Neighborhood Hits	412	Target Neighborhood Hits	1582	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SEZ6L_HUMAN
θ value	0.62314 (rank : 238)	NC score	0.020281 (rank : 382)
Query Neighborhood Hits	412	Target Neighborhood Hits	289	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SORC1_HUMAN
θ value	0.62314 (rank : 239)	NC score	0.011978 (rank : 416)
Query Neighborhood Hits	412	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WY21, Q59GG7, Q5JVT7, Q5JVT8, Q5VY14, Q86WQ1, Q86WQ2, Q9H1Y1, Q9H1Y2	Gene names	SORCS1, SORCS
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (hSorCS).

WBS14_HUMAN
θ value	0.62314 (rank : 240)	NC score	0.037882 (rank : 334)
Query Neighborhood Hits	412	Target Neighborhood Hits	273	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WIRE_MOUSE
θ value	0.62314 (rank : 241)	NC score	0.076268 (rank : 215)
Query Neighborhood Hits	412	Target Neighborhood Hits	310	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YAP1_HUMAN
θ value	0.62314 (rank : 242)	NC score	0.058615 (rank : 273)
Query Neighborhood Hits	412	Target Neighborhood Hits	173	Shared Neighborhood Hits	24
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

AF10_MOUSE
θ value	0.813845 (rank : 243)	NC score	0.023794 (rank : 373)
Query Neighborhood Hits	412	Target Neighborhood Hits	182	Shared Neighborhood Hits	14
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

CPSF6_HUMAN
θ value	0.813845 (rank : 244)	NC score	0.062461 (rank : 257)
Query Neighborhood Hits	412	Target Neighborhood Hits	359	Shared Neighborhood Hits	44
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	0.813845 (rank : 245)	NC score	0.064012 (rank : 249)
Query Neighborhood Hits	412	Target Neighborhood Hits	356	Shared Neighborhood Hits	46
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

HSF1_MOUSE
θ value	0.813845 (rank : 246)	NC score	0.029775 (rank : 355)
Query Neighborhood Hits	412	Target Neighborhood Hits	267	Shared Neighborhood Hits	45
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HTRA1_HUMAN
θ value	0.813845 (rank : 247)	NC score	0.097197 (rank : 196)
Query Neighborhood Hits	412	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA1_MOUSE
θ value	0.813845 (rank : 248)	NC score	0.094398 (rank : 199)
Query Neighborhood Hits	412	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

KCNH6_HUMAN
θ value	0.813845 (rank : 249)	NC score	0.011783 (rank : 419)
Query Neighborhood Hits	412	Target Neighborhood Hits	222	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

MYO9B_HUMAN
θ value	0.813845 (rank : 250)	NC score	0.009825 (rank : 426)
Query Neighborhood Hits	412	Target Neighborhood Hits	641	Shared Neighborhood Hits	58
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PSMD9_MOUSE
θ value	0.813845 (rank : 251)	NC score	0.090382 (rank : 205)
Query Neighborhood Hits	412	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

RERE_MOUSE
θ value	0.813845 (rank : 252)	NC score	0.057401 (rank : 278)
Query Neighborhood Hits	412	Target Neighborhood Hits	785	Shared Neighborhood Hits	98
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RHPN2_MOUSE
θ value	0.813845 (rank : 253)	NC score	0.128702 (rank : 185)
Query Neighborhood Hits	412	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

SIPA1_MOUSE
θ value	0.813845 (rank : 254)	NC score	0.048787 (rank : 308)
Query Neighborhood Hits	412	Target Neighborhood Hits	158	Shared Neighborhood Hits	25
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

TCRG1_HUMAN
θ value	0.813845 (rank : 255)	NC score	0.036111 (rank : 340)
Query Neighborhood Hits	412	Target Neighborhood Hits	929	Shared Neighborhood Hits	58
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

BCAR1_HUMAN
θ value	1.06291 (rank : 256)	NC score	0.043718 (rank : 322)
Query Neighborhood Hits	412	Target Neighborhood Hits	554	Shared Neighborhood Hits	82
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

ENAM_MOUSE
θ value	1.06291 (rank : 257)	NC score	0.036445 (rank : 338)
Query Neighborhood Hits	412	Target Neighborhood Hits	229	Shared Neighborhood Hits	41
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

GIPC2_MOUSE
θ value	1.06291 (rank : 258)	NC score	0.133294 (rank : 180)
Query Neighborhood Hits	412	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

HTRA4_HUMAN
θ value	1.06291 (rank : 259)	NC score	0.086617 (rank : 208)
Query Neighborhood Hits	412	Target Neighborhood Hits	119	Shared Neighborhood Hits	45
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

HXD4_MOUSE
θ value	1.06291 (rank : 260)	NC score	0.005544 (rank : 441)
Query Neighborhood Hits	412	Target Neighborhood Hits	339	Shared Neighborhood Hits	18
SwissProt Accessions	P10628, P97451, Q3UXL6	Gene names	Hoxd4, Hox-4.2, Hoxd-4
Domain Architecture
Description	Homeobox protein Hox-D4 (Hox-4.2) (Hox-5.1).

MLL3_HUMAN
θ value	1.06291 (rank : 261)	NC score	0.062369 (rank : 258)
Query Neighborhood Hits	412	Target Neighborhood Hits	1644	Shared Neighborhood Hits	151
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MPP4_HUMAN
θ value	1.06291 (rank : 262)	NC score	0.386958 (rank : 111)
Query Neighborhood Hits	412	Target Neighborhood Hits	205	Shared Neighborhood Hits	134
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

SDCB2_HUMAN
θ value	1.06291 (rank : 263)	NC score	0.336123 (rank : 143)
Query Neighborhood Hits	412	Target Neighborhood Hits	121	Shared Neighborhood Hits	118
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SF3A2_MOUSE
θ value	1.06291 (rank : 264)	NC score	0.064250 (rank : 247)
Query Neighborhood Hits	412	Target Neighborhood Hits	247	Shared Neighborhood Hits	43
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SON_HUMAN
θ value	1.06291 (rank : 265)	NC score	0.064293 (rank : 246)
Query Neighborhood Hits	412	Target Neighborhood Hits	1568	Shared Neighborhood Hits	156
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TGON1_MOUSE
θ value	1.06291 (rank : 266)	NC score	0.032145 (rank : 349)
Query Neighborhood Hits	412	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

ACRO_HUMAN
θ value	1.38821 (rank : 267)	NC score	0.001631 (rank : 454)
Query Neighborhood Hits	412	Target Neighborhood Hits	291	Shared Neighborhood Hits	26
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

BAT2_HUMAN
θ value	1.38821 (rank : 268)	NC score	0.083373 (rank : 209)
Query Neighborhood Hits	412	Target Neighborhood Hits	931	Shared Neighborhood Hits	135
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EM55_MOUSE
θ value	1.38821 (rank : 269)	NC score	0.314798 (rank : 148)
Query Neighborhood Hits	412	Target Neighborhood Hits	221	Shared Neighborhood Hits	118
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

GIPC2_HUMAN
θ value	1.38821 (rank : 270)	NC score	0.182872 (rank : 174)
Query Neighborhood Hits	412	Target Neighborhood Hits	93	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

MEOX1_HUMAN
θ value	1.38821 (rank : 271)	NC score	0.002896 (rank : 452)
Query Neighborhood Hits	412	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	P50221	Gene names	MEOX1, MOX1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

MPP2_HUMAN
θ value	1.38821 (rank : 272)	NC score	0.254595 (rank : 160)
Query Neighborhood Hits	412	Target Neighborhood Hits	173	Shared Neighborhood Hits	90
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	1.38821 (rank : 273)	NC score	0.258745 (rank : 158)
Query Neighborhood Hits	412	Target Neighborhood Hits	189	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MTSS1_HUMAN
θ value	1.38821 (rank : 274)	NC score	0.043374 (rank : 323)
Query Neighborhood Hits	412	Target Neighborhood Hits	504	Shared Neighborhood Hits	68
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NIBL_HUMAN
θ value	1.38821 (rank : 275)	NC score	0.018988 (rank : 388)
Query Neighborhood Hits	412	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

PTN23_HUMAN
θ value	1.38821 (rank : 276)	NC score	0.068891 (rank : 237)
Query Neighborhood Hits	412	Target Neighborhood Hits	646	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RPGF1_HUMAN
θ value	1.38821 (rank : 277)	NC score	0.051725 (rank : 302)
Query Neighborhood Hits	412	Target Neighborhood Hits	262	Shared Neighborhood Hits	46
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

WIRE_HUMAN
θ value	1.38821 (rank : 278)	NC score	0.075574 (rank : 217)
Query Neighborhood Hits	412	Target Neighborhood Hits	329	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

BCAR1_MOUSE
θ value	1.81305 (rank : 279)	NC score	0.036629 (rank : 336)
Query Neighborhood Hits	412	Target Neighborhood Hits	438	Shared Neighborhood Hits	65
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCOR_HUMAN
θ value	1.81305 (rank : 280)	NC score	0.021373 (rank : 378)
Query Neighborhood Hits	412	Target Neighborhood Hits	609	Shared Neighborhood Hits	52
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CCD96_MOUSE
θ value	1.81305 (rank : 281)	NC score	0.011996 (rank : 415)
Query Neighborhood Hits	412	Target Neighborhood Hits	704	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CTDP1_HUMAN
θ value	1.81305 (rank : 282)	NC score	0.045064 (rank : 320)
Query Neighborhood Hits	412	Target Neighborhood Hits	416	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

EPN3_MOUSE
θ value	1.81305 (rank : 283)	NC score	0.029392 (rank : 357)
Query Neighborhood Hits	412	Target Neighborhood Hits	312	Shared Neighborhood Hits	45
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

MY18A_MOUSE
θ value	1.81305 (rank : 284)	NC score	0.069640 (rank : 234)
Query Neighborhood Hits	412	Target Neighborhood Hits	1989	Shared Neighborhood Hits	165
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SF3A2_HUMAN
θ value	1.81305 (rank : 285)	NC score	0.061312 (rank : 262)
Query Neighborhood Hits	412	Target Neighborhood Hits	263	Shared Neighborhood Hits	39
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SI1L1_HUMAN
θ value	1.81305 (rank : 286)	NC score	0.068903 (rank : 236)
Query Neighborhood Hits	412	Target Neighborhood Hits	162	Shared Neighborhood Hits	43
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SOX10_HUMAN
θ value	1.81305 (rank : 287)	NC score	0.005799 (rank : 440)
Query Neighborhood Hits	412	Target Neighborhood Hits	122	Shared Neighborhood Hits	12
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

T240L_MOUSE
θ value	1.81305 (rank : 288)	NC score	0.020375 (rank : 381)
Query Neighborhood Hits	412	Target Neighborhood Hits	143	Shared Neighborhood Hits	23
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

TREF1_MOUSE
θ value	1.81305 (rank : 289)	NC score	0.014817 (rank : 400)
Query Neighborhood Hits	412	Target Neighborhood Hits	682	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

ZAR1_MOUSE
θ value	1.81305 (rank : 290)	NC score	0.037624 (rank : 335)
Query Neighborhood Hits	412	Target Neighborhood Hits	254	Shared Neighborhood Hits	34
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

CITE4_MOUSE
θ value	2.36792 (rank : 291)	NC score	0.030970 (rank : 351)
Query Neighborhood Hits	412	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CN155_HUMAN
θ value	2.36792 (rank : 292)	NC score	0.059281 (rank : 269)
Query Neighborhood Hits	412	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

DIAP2_MOUSE
θ value	2.36792 (rank : 293)	NC score	0.023921 (rank : 372)
Query Neighborhood Hits	412	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

HEN1_MOUSE
θ value	2.36792 (rank : 294)	NC score	0.009784 (rank : 427)
Query Neighborhood Hits	412	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

JHD3B_MOUSE
θ value	2.36792 (rank : 295)	NC score	0.016276 (rank : 394)
Query Neighborhood Hits	412	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

K1802_MOUSE
θ value	2.36792 (rank : 296)	NC score	0.048536 (rank : 309)
Query Neighborhood Hits	412	Target Neighborhood Hits	1596	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NCOA1_HUMAN
θ value	2.36792 (rank : 297)	NC score	0.015876 (rank : 398)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

PER3_HUMAN
θ value	2.36792 (rank : 298)	NC score	0.033270 (rank : 346)
Query Neighborhood Hits	412	Target Neighborhood Hits	479	Shared Neighborhood Hits	62
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SH2D3_MOUSE
θ value	2.36792 (rank : 299)	NC score	0.012401 (rank : 413)
Query Neighborhood Hits	412	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

ALO17_HUMAN
θ value	3.0926 (rank : 300)	NC score	0.030513 (rank : 354)
Query Neighborhood Hits	412	Target Neighborhood Hits	317	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ANTR1_HUMAN
θ value	3.0926 (rank : 301)	NC score	0.025761 (rank : 369)
Query Neighborhood Hits	412	Target Neighborhood Hits	128	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ANTR1_MOUSE
θ value	3.0926 (rank : 302)	NC score	0.026223 (rank : 368)
Query Neighborhood Hits	412	Target Neighborhood Hits	143	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

CDK8_HUMAN
θ value	3.0926 (rank : 303)	NC score	-0.000919 (rank : 461)
Query Neighborhood Hits	412	Target Neighborhood Hits	831	Shared Neighborhood Hits	14
SwissProt Accessions	P49336	Gene names	CDK8
Domain Architecture
Description	Cell division protein kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Protein kinase K35).

CRSP7_HUMAN
θ value	3.0926 (rank : 304)	NC score	0.027897 (rank : 359)
Query Neighborhood Hits	412	Target Neighborhood Hits	247	Shared Neighborhood Hits	31
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

DAAM1_HUMAN
θ value	3.0926 (rank : 305)	NC score	0.020234 (rank : 383)
Query Neighborhood Hits	412	Target Neighborhood Hits	483	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DOK7_MOUSE
θ value	3.0926 (rank : 306)	NC score	0.026970 (rank : 364)
Query Neighborhood Hits	412	Target Neighborhood Hits	169	Shared Neighborhood Hits	31
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

FHOD1_MOUSE
θ value	3.0926 (rank : 307)	NC score	0.029419 (rank : 356)
Query Neighborhood Hits	412	Target Neighborhood Hits	217	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GIT1_HUMAN
θ value	3.0926 (rank : 308)	NC score	0.013321 (rank : 408)
Query Neighborhood Hits	412	Target Neighborhood Hits	336	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	3.0926 (rank : 309)	NC score	0.012505 (rank : 412)
Query Neighborhood Hits	412	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

HUWE1_MOUSE
θ value	3.0926 (rank : 310)	NC score	0.013532 (rank : 407)
Query Neighborhood Hits	412	Target Neighborhood Hits	406	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HXA3_MOUSE
θ value	3.0926 (rank : 311)	NC score	0.013270 (rank : 409)
Query Neighborhood Hits	412	Target Neighborhood Hits	558	Shared Neighborhood Hits	54
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IF4G1_HUMAN
θ value	3.0926 (rank : 312)	NC score	0.045287 (rank : 316)
Query Neighborhood Hits	412	Target Neighborhood Hits	347	Shared Neighborhood Hits	50
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

M3K5_HUMAN
θ value	3.0926 (rank : 313)	NC score	-0.000156 (rank : 459)
Query Neighborhood Hits	412	Target Neighborhood Hits	868	Shared Neighborhood Hits	15
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

MMP15_HUMAN
θ value	3.0926 (rank : 314)	NC score	0.003347 (rank : 451)
Query Neighborhood Hits	412	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MTSS1_MOUSE
θ value	3.0926 (rank : 315)	NC score	0.047542 (rank : 312)
Query Neighborhood Hits	412	Target Neighborhood Hits	592	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NFM_MOUSE
θ value	3.0926 (rank : 316)	NC score	0.003435 (rank : 450)
Query Neighborhood Hits	412	Target Neighborhood Hits	1159	Shared Neighborhood Hits	45
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PCLO_HUMAN
θ value	3.0926 (rank : 317)	NC score	0.071005 (rank : 231)
Query Neighborhood Hits	412	Target Neighborhood Hits	2046	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RHBD3_HUMAN
θ value	3.0926 (rank : 318)	NC score	0.017579 (rank : 391)
Query Neighborhood Hits	412	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3P4, Q6I9X3, Q9UGQ7	Gene names	RHBDD3, C22orf3
Domain Architecture
Description	Rhomboid domain-containing protein 3.

SGIP1_HUMAN
θ value	3.0926 (rank : 319)	NC score	0.040201 (rank : 331)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TFE2_MOUSE
θ value	3.0926 (rank : 320)	NC score	0.011916 (rank : 417)
Query Neighborhood Hits	412	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

TGON2_MOUSE
θ value	3.0926 (rank : 321)	NC score	0.027746 (rank : 361)
Query Neighborhood Hits	412	Target Neighborhood Hits	277	Shared Neighborhood Hits	29
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TIF1G_MOUSE
θ value	3.0926 (rank : 322)	NC score	0.014056 (rank : 404)
Query Neighborhood Hits	412	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ZBT45_HUMAN
θ value	3.0926 (rank : 323)	NC score	-0.006665 (rank : 462)
Query Neighborhood Hits	412	Target Neighborhood Hits	901	Shared Neighborhood Hits	32
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

ZBTB5_MOUSE
θ value	3.0926 (rank : 324)	NC score	-0.008423 (rank : 464)
Query Neighborhood Hits	412	Target Neighborhood Hits	801	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).

AXN1_MOUSE
θ value	4.03905 (rank : 325)	NC score	0.027647 (rank : 362)
Query Neighborhood Hits	412	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

BSN_HUMAN
θ value	4.03905 (rank : 326)	NC score	0.058697 (rank : 272)
Query Neighborhood Hits	412	Target Neighborhood Hits	1537	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CROCC_HUMAN
θ value	4.03905 (rank : 327)	NC score	0.005311 (rank : 444)
Query Neighborhood Hits	412	Target Neighborhood Hits	1409	Shared Neighborhood Hits	49
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

EM55_HUMAN
θ value	4.03905 (rank : 328)	NC score	0.315866 (rank : 147)
Query Neighborhood Hits	412	Target Neighborhood Hits	228	Shared Neighborhood Hits	121
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

IWS1_MOUSE
θ value	4.03905 (rank : 329)	NC score	0.041716 (rank : 326)
Query Neighborhood Hits	412	Target Neighborhood Hits	1258	Shared Neighborhood Hits	110
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MEGF9_MOUSE
θ value	4.03905 (rank : 330)	NC score	0.020952 (rank : 380)
Query Neighborhood Hits	412	Target Neighborhood Hits	896	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NCOA2_HUMAN
θ value	4.03905 (rank : 331)	NC score	0.015338 (rank : 399)
Query Neighborhood Hits	412	Target Neighborhood Hits	281	Shared Neighborhood Hits	28
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PELP1_HUMAN
θ value	4.03905 (rank : 332)	NC score	0.035164 (rank : 342)
Query Neighborhood Hits	412	Target Neighborhood Hits	596	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PRR12_HUMAN
θ value	4.03905 (rank : 333)	NC score	0.073411 (rank : 223)
Query Neighborhood Hits	412	Target Neighborhood Hits	460	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR8_HUMAN
θ value	4.03905 (rank : 334)	NC score	0.042490 (rank : 325)
Query Neighborhood Hits	412	Target Neighborhood Hits	217	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PSCBP_HUMAN
θ value	4.03905 (rank : 335)	NC score	0.354044 (rank : 130)
Query Neighborhood Hits	412	Target Neighborhood Hits	123	Shared Neighborhood Hits	113
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PSIP1_HUMAN
θ value	4.03905 (rank : 336)	NC score	0.010596 (rank : 421)
Query Neighborhood Hits	412	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

SH2D3_HUMAN
θ value	4.03905 (rank : 337)	NC score	0.012965 (rank : 410)
Query Neighborhood Hits	412	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SI1L1_MOUSE
θ value	4.03905 (rank : 338)	NC score	0.066595 (rank : 242)
Query Neighborhood Hits	412	Target Neighborhood Hits	189	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SIGL5_HUMAN
θ value	4.03905 (rank : 339)	NC score	0.001551 (rank : 455)
Query Neighborhood Hits	412	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

SMRC1_MOUSE
θ value	4.03905 (rank : 340)	NC score	0.019692 (rank : 385)
Query Neighborhood Hits	412	Target Neighborhood Hits	459	Shared Neighborhood Hits	40
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SRRM2_MOUSE
θ value	4.03905 (rank : 341)	NC score	0.087207 (rank : 207)
Query Neighborhood Hits	412	Target Neighborhood Hits	1470	Shared Neighborhood Hits	141
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

THSD1_MOUSE
θ value	4.03905 (rank : 342)	NC score	0.012595 (rank : 411)
Query Neighborhood Hits	412	Target Neighborhood Hits	153	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

WASL_MOUSE
θ value	4.03905 (rank : 343)	NC score	0.051057 (rank : 305)
Query Neighborhood Hits	412	Target Neighborhood Hits	339	Shared Neighborhood Hits	56
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ADDB_MOUSE
θ value	5.27518 (rank : 344)	NC score	0.017739 (rank : 390)
Query Neighborhood Hits	412	Target Neighborhood Hits	574	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AKA10_MOUSE
θ value	5.27518 (rank : 345)	NC score	0.023054 (rank : 374)
Query Neighborhood Hits	412	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

ANR11_HUMAN
θ value	5.27518 (rank : 346)	NC score	0.021683 (rank : 376)
Query Neighborhood Hits	412	Target Neighborhood Hits	1289	Shared Neighborhood Hits	94
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

AP3B1_MOUSE
θ value	5.27518 (rank : 347)	NC score	0.011889 (rank : 418)
Query Neighborhood Hits	412	Target Neighborhood Hits	302	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

BCL9_MOUSE
θ value	5.27518 (rank : 348)	NC score	0.068612 (rank : 238)
Query Neighborhood Hits	412	Target Neighborhood Hits	770	Shared Neighborhood Hits	112
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CAC1B_MOUSE
θ value	5.27518 (rank : 349)	NC score	0.005450 (rank : 442)
Query Neighborhood Hits	412	Target Neighborhood Hits	351	Shared Neighborhood Hits	27
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CBL_MOUSE
θ value	5.27518 (rank : 350)	NC score	0.032382 (rank : 348)
Query Neighborhood Hits	412	Target Neighborhood Hits	426	Shared Neighborhood Hits	47
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBP_HUMAN
θ value	5.27518 (rank : 351)	NC score	0.054667 (rank : 287)
Query Neighborhood Hits	412	Target Neighborhood Hits	941	Shared Neighborhood Hits	124
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DLX5_MOUSE
θ value	5.27518 (rank : 352)	NC score	0.001053 (rank : 456)
Query Neighborhood Hits	412	Target Neighborhood Hits	434	Shared Neighborhood Hits	21
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

EAN57_HUMAN
θ value	5.27518 (rank : 353)	NC score	0.027509 (rank : 363)
Query Neighborhood Hits	412	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

EPS8_HUMAN
θ value	5.27518 (rank : 354)	NC score	0.006512 (rank : 436)
Query Neighborhood Hits	412	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EVL_HUMAN
θ value	5.27518 (rank : 355)	NC score	0.021145 (rank : 379)
Query Neighborhood Hits	412	Target Neighborhood Hits	260	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FA44A_HUMAN
θ value	5.27518 (rank : 356)	NC score	0.012233 (rank : 414)
Query Neighborhood Hits	412	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

FMN2_HUMAN
θ value	5.27518 (rank : 357)	NC score	0.045131 (rank : 319)
Query Neighborhood Hits	412	Target Neighborhood Hits	484	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FOXK2_HUMAN
θ value	5.27518 (rank : 358)	NC score	0.008003 (rank : 430)
Query Neighborhood Hits	412	Target Neighborhood Hits	190	Shared Neighborhood Hits	20
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

HCN2_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.019121 (rank : 387)
Query Neighborhood Hits	412	Target Neighborhood Hits	369	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

KCC2B_HUMAN
θ value	5.27518 (rank : 360)	NC score	0.000346 (rank : 457)
Query Neighborhood Hits	412	Target Neighborhood Hits	866	Shared Neighborhood Hits	23
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

PKP4_HUMAN
θ value	5.27518 (rank : 361)	NC score	0.004411 (rank : 448)
Query Neighborhood Hits	412	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

SI1L2_HUMAN
θ value	5.27518 (rank : 362)	NC score	0.074292 (rank : 220)
Query Neighborhood Hits	412	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	5.27518 (rank : 363)	NC score	0.072551 (rank : 225)
Query Neighborhood Hits	412	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

TAB3_MOUSE
θ value	5.27518 (rank : 364)	NC score	0.031859 (rank : 350)
Query Neighborhood Hits	412	Target Neighborhood Hits	273	Shared Neighborhood Hits	43
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TXLNB_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.024316 (rank : 371)
Query Neighborhood Hits	412	Target Neighborhood Hits	912	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

WASL_HUMAN
θ value	5.27518 (rank : 366)	NC score	0.046928 (rank : 314)
Query Neighborhood Hits	412	Target Neighborhood Hits	312	Shared Neighborhood Hits	49
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

YAP1_MOUSE
θ value	5.27518 (rank : 367)	NC score	0.060280 (rank : 264)
Query Neighborhood Hits	412	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ABI2_HUMAN
θ value	6.88961 (rank : 368)	NC score	0.028070 (rank : 358)
Query Neighborhood Hits	412	Target Neighborhood Hits	350	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	6.88961 (rank : 369)	NC score	0.016546 (rank : 393)
Query Neighborhood Hits	412	Target Neighborhood Hits	266	Shared Neighborhood Hits	25
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ARI1A_HUMAN
θ value	6.88961 (rank : 370)	NC score	0.051640 (rank : 303)
Query Neighborhood Hits	412	Target Neighborhood Hits	787	Shared Neighborhood Hits	97
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CAR14_MOUSE
θ value	6.88961 (rank : 371)	NC score	0.057721 (rank : 276)
Query Neighborhood Hits	412	Target Neighborhood Hits	526	Shared Neighborhood Hits	37
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

CD2L7_HUMAN
θ value	6.88961 (rank : 372)	NC score	0.004662 (rank : 447)
Query Neighborhood Hits	412	Target Neighborhood Hits	1275	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

ENAH_HUMAN
θ value	6.88961 (rank : 373)	NC score	0.037883 (rank : 333)
Query Neighborhood Hits	412	Target Neighborhood Hits	784	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EVL_MOUSE
θ value	6.88961 (rank : 374)	NC score	0.021535 (rank : 377)
Query Neighborhood Hits	412	Target Neighborhood Hits	203	Shared Neighborhood Hits	30
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

EXO1_MOUSE
θ value	6.88961 (rank : 375)	NC score	0.009973 (rank : 424)
Query Neighborhood Hits	412	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

FMNL_MOUSE
θ value	6.88961 (rank : 376)	NC score	0.026895 (rank : 365)
Query Neighborhood Hits	412	Target Neighborhood Hits	428	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FOG1_HUMAN
θ value	6.88961 (rank : 377)	NC score	0.001784 (rank : 453)
Query Neighborhood Hits	412	Target Neighborhood Hits	981	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FX4L1_HUMAN
θ value	6.88961 (rank : 378)	NC score	0.003743 (rank : 449)
Query Neighborhood Hits	412	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NU39	Gene names	FOXD4L1
Domain Architecture
Description	Forkhead box protein D4-like 1.

HTF4_HUMAN
θ value	6.88961 (rank : 379)	NC score	0.009545 (rank : 428)
Query Neighborhood Hits	412	Target Neighborhood Hits	152	Shared Neighborhood Hits	14
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

MBD1_HUMAN
θ value	6.88961 (rank : 380)	NC score	0.007231 (rank : 433)
Query Neighborhood Hits	412	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MINT_HUMAN
θ value	6.88961 (rank : 381)	NC score	0.030769 (rank : 352)
Query Neighborhood Hits	412	Target Neighborhood Hits	1291	Shared Neighborhood Hits	91
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL2_HUMAN
θ value	6.88961 (rank : 382)	NC score	0.046463 (rank : 315)
Query Neighborhood Hits	412	Target Neighborhood Hits	1788	Shared Neighborhood Hits	144
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
θ value	6.88961 (rank : 383)	NC score	0.045171 (rank : 317)
Query Neighborhood Hits	412	Target Neighborhood Hits	722	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NFAC1_MOUSE
θ value	6.88961 (rank : 384)	NC score	0.005854 (rank : 439)
Query Neighborhood Hits	412	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NOG2_MOUSE
θ value	6.88961 (rank : 385)	NC score	0.009458 (rank : 429)
Query Neighborhood Hits	412	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.

NOL11_HUMAN
θ value	6.88961 (rank : 386)	NC score	0.013960 (rank : 405)
Query Neighborhood Hits	412	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8H0, Q7L5S1, Q9UG18	Gene names	NOL11
Domain Architecture	No domain graphic available
Description	Nucleolar protein 11.

PAF49_MOUSE
θ value	6.88961 (rank : 387)	NC score	0.019386 (rank : 386)
Query Neighborhood Hits	412	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

STIM1_HUMAN
θ value	6.88961 (rank : 388)	NC score	0.005381 (rank : 443)
Query Neighborhood Hits	412	Target Neighborhood Hits	665	Shared Neighborhood Hits	22
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TEAD2_HUMAN
θ value	6.88961 (rank : 389)	NC score	0.004994 (rank : 446)
Query Neighborhood Hits	412	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q15562, Q96IG3	Gene names	TEAD2, TEF4
Domain Architecture
Description	Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2).

WASF4_HUMAN
θ value	6.88961 (rank : 390)	NC score	0.033347 (rank : 345)
Query Neighborhood Hits	412	Target Neighborhood Hits	282	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ZCH11_HUMAN
θ value	6.88961 (rank : 391)	NC score	0.016224 (rank : 396)
Query Neighborhood Hits	412	Target Neighborhood Hits	278	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ABCA4_MOUSE
θ value	8.99809 (rank : 392)	NC score	-0.000661 (rank : 460)
Query Neighborhood Hits	412	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ATF7_HUMAN
θ value	8.99809 (rank : 393)	NC score	0.006669 (rank : 435)
Query Neighborhood Hits	412	Target Neighborhood Hits	333	Shared Neighborhood Hits	13
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

CN004_HUMAN
θ value	8.99809 (rank : 394)	NC score	0.014374 (rank : 403)
Query Neighborhood Hits	412	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

DIAP1_MOUSE
θ value	8.99809 (rank : 395)	NC score	0.026543 (rank : 366)
Query Neighborhood Hits	412	Target Neighborhood Hits	839	Shared Neighborhood Hits	54
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

ENAH_MOUSE
θ value	8.99809 (rank : 396)	NC score	0.056157 (rank : 284)
Query Neighborhood Hits	412	Target Neighborhood Hits	919	Shared Neighborhood Hits	89
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FAF1_HUMAN
θ value	8.99809 (rank : 397)	NC score	0.010117 (rank : 422)
Query Neighborhood Hits	412	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

FAF1_MOUSE
θ value	8.99809 (rank : 398)	NC score	0.010090 (rank : 423)
Query Neighborhood Hits	412	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

FMNL_HUMAN
θ value	8.99809 (rank : 399)	NC score	0.033990 (rank : 343)
Query Neighborhood Hits	412	Target Neighborhood Hits	529	Shared Neighborhood Hits	53
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FOXGB_MOUSE
θ value	8.99809 (rank : 400)	NC score	0.006454 (rank : 437)
Query Neighborhood Hits	412	Target Neighborhood Hits	148	Shared Neighborhood Hits	23
SwissProt Accessions	Q60987, Q80VP3	Gene names	Foxg1b, Fkhl1, Foxg1, Hfhbf1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1).

FOXP4_MOUSE
θ value	8.99809 (rank : 401)	NC score	0.011720 (rank : 420)
Query Neighborhood Hits	412	Target Neighborhood Hits	211	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

HXD13_HUMAN
θ value	8.99809 (rank : 402)	NC score	-0.000149 (rank : 458)
Query Neighborhood Hits	412	Target Neighborhood Hits	332	Shared Neighborhood Hits	12
SwissProt Accessions	P35453	Gene names	HOXD13, HOX4I
Domain Architecture
Description	Homeobox protein Hox-D13 (Hox-4I).

JPH2_MOUSE
θ value	8.99809 (rank : 403)	NC score	0.014644 (rank : 402)
Query Neighborhood Hits	412	Target Neighborhood Hits	279	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LPPRC_HUMAN
θ value	8.99809 (rank : 404)	NC score	0.009858 (rank : 425)
Query Neighborhood Hits	412	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	P42704	Gene names	LRPPRC, LRP130
Domain Architecture	No domain graphic available
Description	130 kDa leucine-rich protein (LRP 130) (GP130) (Leucine-rich PPR motif-containing protein).

MOCOS_MOUSE
θ value	8.99809 (rank : 405)	NC score	0.007261 (rank : 432)
Query Neighborhood Hits	412	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q14CH1	Gene names	Mocos
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS).

NPAS3_HUMAN
θ value	8.99809 (rank : 406)	NC score	0.005038 (rank : 445)
Query Neighborhood Hits	412	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NUP62_MOUSE
θ value	8.99809 (rank : 407)	NC score	0.014717 (rank : 401)
Query Neighborhood Hits	412	Target Neighborhood Hits	200	Shared Neighborhood Hits	10
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

PHC3_MOUSE
θ value	8.99809 (rank : 408)	NC score	0.016606 (rank : 392)
Query Neighborhood Hits	412	Target Neighborhood Hits	194	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PPRB_HUMAN
θ value	8.99809 (rank : 409)	NC score	0.036565 (rank : 337)
Query Neighborhood Hits	412	Target Neighborhood Hits	311	Shared Neighborhood Hits	38
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

TLE1_MOUSE
θ value	8.99809 (rank : 410)	NC score	0.007946 (rank : 431)
Query Neighborhood Hits	412	Target Neighborhood Hits	491	Shared Neighborhood Hits	38
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TM55A_MOUSE
θ value	8.99809 (rank : 411)	NC score	0.005913 (rank : 438)
Query Neighborhood Hits	412	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZX7	Gene names	Tmem55a
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55A (EC 3.1.3.-) (Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase II).

ZN142_HUMAN
θ value	8.99809 (rank : 412)	NC score	-0.007446 (rank : 463)
Query Neighborhood Hits	412	Target Neighborhood Hits	1007	Shared Neighborhood Hits	55
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ATN1_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.051294 (rank : 304)
Query Neighborhood Hits	412	Target Neighborhood Hits	676	Shared Neighborhood Hits	83
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAG3_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.057137 (rank : 281)
Query Neighborhood Hits	412	Target Neighborhood Hits	314	Shared Neighborhood Hits	61
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.063157 (rank : 254)
Query Neighborhood Hits	412	Target Neighborhood Hits	513	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BAT2_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.069164 (rank : 235)
Query Neighborhood Hits	412	Target Neighborhood Hits	947	Shared Neighborhood Hits	134
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.063718 (rank : 252)
Query Neighborhood Hits	412	Target Neighborhood Hits	2057	Shared Neighborhood Hits	178
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAR14_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.064402 (rank : 245)
Query Neighborhood Hits	412	Target Neighborhood Hits	449	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CNKR2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.093638 (rank : 201)
Query Neighborhood Hits	412	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.093724 (rank : 200)
Query Neighborhood Hits	412	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CS016_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.057282 (rank : 279)
Query Neighborhood Hits	412	Target Neighborhood Hits	310	Shared Neighborhood Hits	56
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSKP_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.102609 (rank : 191)
Query Neighborhood Hits	412	Target Neighborhood Hits	1022	Shared Neighborhood Hits	122
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.100084 (rank : 193)
Query Neighborhood Hits	412	Target Neighborhood Hits	1027	Shared Neighborhood Hits	122
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

GGN_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.064444 (rank : 244)
Query Neighborhood Hits	412	Target Neighborhood Hits	269	Shared Neighborhood Hits	48
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HTRA2_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.053721 (rank : 290)
Query Neighborhood Hits	412	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.050090 (rank : 306)
Query Neighborhood Hits	412	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

KGUA_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.186177 (rank : 173)
Query Neighborhood Hits	412	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.188212 (rank : 172)
Query Neighborhood Hits	412	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LRRC1_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.058987 (rank : 271)
Query Neighborhood Hits	412	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRRC1_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.059294 (rank : 268)
Query Neighborhood Hits	412	Target Neighborhood Hits	281	Shared Neighborhood Hits	6
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

MBD6_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.052006 (rank : 301)
Query Neighborhood Hits	412	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.059519 (rank : 267)
Query Neighborhood Hits	412	Target Neighborhood Hits	1446	Shared Neighborhood Hits	144
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.063995 (rank : 250)
Query Neighborhood Hits	412	Target Neighborhood Hits	998	Shared Neighborhood Hits	130
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MPP4_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.336811 (rank : 141)
Query Neighborhood Hits	412	Target Neighborhood Hits	188	Shared Neighborhood Hits	116
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP6_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.250156 (rank : 163)
Query Neighborhood Hits	412	Target Neighborhood Hits	180	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.254038 (rank : 161)
Query Neighborhood Hits	412	Target Neighborhood Hits	187	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MY18A_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.062805 (rank : 256)
Query Neighborhood Hits	412	Target Neighborhood Hits	1929	Shared Neighborhood Hits	162
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NACAM_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.072794 (rank : 224)
Query Neighborhood Hits	412	Target Neighborhood Hits	1866	Shared Neighborhood Hits	170
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.057628 (rank : 277)
Query Neighborhood Hits	412	Target Neighborhood Hits	1202	Shared Neighborhood Hits	132
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PDZD6_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.125216 (rank : 187)
Query Neighborhood Hits	412	Target Neighborhood Hits	81	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PRAX_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.067447 (rank : 240)
Query Neighborhood Hits	412	Target Neighborhood Hits	215	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.088442 (rank : 206)
Query Neighborhood Hits	412	Target Neighborhood Hits	199	Shared Neighborhood Hits	54
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRB3_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.056642 (rank : 282)
Query Neighborhood Hits	412	Target Neighborhood Hits	318	Shared Neighborhood Hits	45
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRP1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.057970 (rank : 275)
Query Neighborhood Hits	412	Target Neighborhood Hits	385	Shared Neighborhood Hits	56
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.058188 (rank : 274)
Query Neighborhood Hits	412	Target Neighborhood Hits	347	Shared Neighborhood Hits	50
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RERE_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.052027 (rank : 300)
Query Neighborhood Hits	412	Target Neighborhood Hits	779	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RHPN2_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.077262 (rank : 214)
Query Neighborhood Hits	412	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RNF41_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.081140 (rank : 212)
Query Neighborhood Hits	412	Target Neighborhood Hits	226	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.081315 (rank : 211)
Query Neighborhood Hits	412	Target Neighborhood Hits	224	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SAV1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.052934 (rank : 296)
Query Neighborhood Hits	412	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.052872 (rank : 297)
Query Neighborhood Hits	412	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SELPL_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.054067 (rank : 289)
Query Neighborhood Hits	412	Target Neighborhood Hits	588	Shared Neighborhood Hits	86
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SI1L3_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.062944 (rank : 255)
Query Neighborhood Hits	412	Target Neighborhood Hits	305	Shared Neighborhood Hits	75
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SRRM1_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.057165 (rank : 280)
Query Neighborhood Hits	412	Target Neighborhood Hits	690	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.071709 (rank : 228)
Query Neighborhood Hits	412	Target Neighborhood Hits	966	Shared Neighborhood Hits	122
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.071294 (rank : 230)
Query Neighborhood Hits	412	Target Neighborhood Hits	1296	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYNPO_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.054144 (rank : 288)
Query Neighborhood Hits	412	Target Neighborhood Hits	281	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SYNPO_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.053235 (rank : 294)
Query Neighborhood Hits	412	Target Neighborhood Hits	242	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TCOF_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.060193 (rank : 265)
Query Neighborhood Hits	412	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TGON2_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.053385 (rank : 292)
Query Neighborhood Hits	412	Target Neighborhood Hits	1037	Shared Neighborhood Hits	96
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

WASIP_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.067474 (rank : 239)
Query Neighborhood Hits	412	Target Neighborhood Hits	458	Shared Neighborhood Hits	70
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.061251 (rank : 263)
Query Neighborhood Hits	412	Target Neighborhood Hits	392	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.053382 (rank : 293)
Query Neighborhood Hits	412	Target Neighborhood Hits	670	Shared Neighborhood Hits	90
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZYX_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.052334 (rank : 299)
Query Neighborhood Hits	412	Target Neighborhood Hits	387	Shared Neighborhood Hits	56
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

Hits sorted by NC score

WHRN_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	412	Target Neighborhood Hits	412	Shared Neighborhood Hits	412
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WHRN_HUMAN
NC score	0.973602 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	412	Target Neighborhood Hits	325	Shared Neighborhood Hits	247
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

PDZD7_HUMAN
NC score	0.894292 (rank : 3)	θ value	3.26607e-42 (rank : 3)
Query Neighborhood Hits	412	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

USH1C_HUMAN
NC score	0.857113 (rank : 4)	θ value	4.00176e-32 (rank : 4)
Query Neighborhood Hits	412	Target Neighborhood Hits	327	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
NC score	0.810065 (rank : 5)	θ value	1.98606e-31 (rank : 5)
Query Neighborhood Hits	412	Target Neighborhood Hits	557	Shared Neighborhood Hits	225
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PDZ11_HUMAN
NC score	0.766587 (rank : 6)	θ value	3.29651e-10 (rank : 35)
Query Neighborhood Hits	412	Target Neighborhood Hits	160	Shared Neighborhood Hits	155
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
NC score	0.762868 (rank : 7)	θ value	3.29651e-10 (rank : 36)
Query Neighborhood Hits	412	Target Neighborhood Hits	154	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LIN7B_HUMAN
NC score	0.752938 (rank : 8)	θ value	2.79066e-09 (rank : 43)
Query Neighborhood Hits	412	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.750327 (rank : 9)	θ value	3.64472e-09 (rank : 47)
Query Neighborhood Hits	412	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7A_MOUSE
NC score	0.750123 (rank : 10)	θ value	3.64472e-09 (rank : 46)
Query Neighborhood Hits	412	Target Neighborhood Hits	193	Shared Neighborhood Hits	182
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7A_HUMAN
NC score	0.749865 (rank : 11)	θ value	3.64472e-09 (rank : 45)
Query Neighborhood Hits	412	Target Neighborhood Hits	193	Shared Neighborhood Hits	182
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7C_HUMAN
NC score	0.747947 (rank : 12)	θ value	8.11959e-09 (rank : 49)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	184
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.747947 (rank : 13)	θ value	8.11959e-09 (rank : 50)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	184
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

SYJ2B_HUMAN
NC score	0.744141 (rank : 14)	θ value	7.1131e-05 (rank : 93)
Query Neighborhood Hits	412	Target Neighborhood Hits	162	Shared Neighborhood Hits	158
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

INADL_MOUSE
NC score	0.732048 (rank : 15)	θ value	6.00763e-12 (rank : 26)
Query Neighborhood Hits	412	Target Neighborhood Hits	290	Shared Neighborhood Hits	200
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

MPDZ_MOUSE
NC score	0.727742 (rank : 16)	θ value	5.43371e-13 (rank : 21)
Query Neighborhood Hits	412	Target Neighborhood Hits	298	Shared Neighborhood Hits	195
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPDZ_HUMAN
NC score	0.724394 (rank : 17)	θ value	4.59992e-12 (rank : 24)
Query Neighborhood Hits	412	Target Neighborhood Hits	261	Shared Neighborhood Hits	197
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

INADL_HUMAN
NC score	0.724348 (rank : 18)	θ value	1.74796e-11 (rank : 29)
Query Neighborhood Hits	412	Target Neighborhood Hits	260	Shared Neighborhood Hits	188
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

PDZD1_MOUSE
NC score	0.714129 (rank : 19)	θ value	3.52202e-12 (rank : 22)
Query Neighborhood Hits	412	Target Neighborhood Hits	191	Shared Neighborhood Hits	171
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHERF_MOUSE
NC score	0.713562 (rank : 20)	θ value	6.00763e-12 (rank : 27)
Query Neighborhood Hits	412	Target Neighborhood Hits	195	Shared Neighborhood Hits	167
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_HUMAN
NC score	0.707505 (rank : 21)	θ value	1.86753e-13 (rank : 17)
Query Neighborhood Hits	412	Target Neighborhood Hits	190	Shared Neighborhood Hits	168
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
NC score	0.707175 (rank : 22)	θ value	4.59992e-12 (rank : 25)
Query Neighborhood Hits	412	Target Neighborhood Hits	197	Shared Neighborhood Hits	179
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
NC score	0.700873 (rank : 23)	θ value	7.84624e-12 (rank : 28)
Query Neighborhood Hits	412	Target Neighborhood Hits	194	Shared Neighborhood Hits	179
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

TX1B3_HUMAN
NC score	0.698797 (rank : 24)	θ value	1.43324e-05 (rank : 84)
Query Neighborhood Hits	412	Target Neighborhood Hits	161	Shared Neighborhood Hits	160
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
NC score	0.696644 (rank : 25)	θ value	1.43324e-05 (rank : 85)
Query Neighborhood Hits	412	Target Neighborhood Hits	158	Shared Neighborhood Hits	157
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PDZD1_HUMAN
NC score	0.695483 (rank : 26)	θ value	1.53129e-07 (rank : 60)
Query Neighborhood Hits	412	Target Neighborhood Hits	190	Shared Neighborhood Hits	170
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

GOPC_MOUSE
NC score	0.680537 (rank : 27)	θ value	5.62301e-10 (rank : 38)
Query Neighborhood Hits	412	Target Neighborhood Hits	323	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

DLG4_MOUSE
NC score	0.679902 (rank : 28)	θ value	6.85773e-16 (rank : 7)
Query Neighborhood Hits	412	Target Neighborhood Hits	282	Shared Neighborhood Hits	180
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.678451 (rank : 29)	θ value	1.52774e-15 (rank : 9)
Query Neighborhood Hits	412	Target Neighborhood Hits	286	Shared Neighborhood Hits	178
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

GOPC_HUMAN
NC score	0.670236 (rank : 30)	θ value	5.62301e-10 (rank : 37)
Query Neighborhood Hits	412	Target Neighborhood Hits	377	Shared Neighborhood Hits	169
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

DLG3_MOUSE
NC score	0.668068 (rank : 31)	θ value	7.58209e-15 (rank : 13)
Query Neighborhood Hits	412	Target Neighborhood Hits	274	Shared Neighborhood Hits	181
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

PAR3L_HUMAN
NC score	0.666972 (rank : 32)	θ value	1.80886e-08 (rank : 52)
Query Neighborhood Hits	412	Target Neighborhood Hits	297	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

DLG3_HUMAN
NC score	0.666231 (rank : 33)	θ value	7.58209e-15 (rank : 12)
Query Neighborhood Hits	412	Target Neighborhood Hits	269	Shared Neighborhood Hits	180
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_HUMAN
NC score	0.663214 (rank : 34)	θ value	6.85773e-16 (rank : 6)
Query Neighborhood Hits	412	Target Neighborhood Hits	290	Shared Neighborhood Hits	172
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

PDZD3_HUMAN
NC score	0.661959 (rank : 35)	θ value	4.76016e-09 (rank : 48)
Query Neighborhood Hits	412	Target Neighborhood Hits	180	Shared Neighborhood Hits	164
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

DLG1_MOUSE
NC score	0.661336 (rank : 36)	θ value	8.95645e-16 (rank : 8)
Query Neighborhood Hits	412	Target Neighborhood Hits	285	Shared Neighborhood Hits	174
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

MAGI1_HUMAN
NC score	0.659335 (rank : 37)	θ value	2.28291e-11 (rank : 30)
Query Neighborhood Hits	412	Target Neighborhood Hits	388	Shared Neighborhood Hits	201
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.658774 (rank : 38)	θ value	5.43371e-13 (rank : 20)
Query Neighborhood Hits	412	Target Neighborhood Hits	403	Shared Neighborhood Hits	205
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PDZD2_HUMAN
NC score	0.657771 (rank : 39)	θ value	1.06045e-08 (rank : 51)
Query Neighborhood Hits	412	Target Neighborhood Hits	772	Shared Neighborhood Hits	230
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

GRIP2_HUMAN
NC score	0.655270 (rank : 40)	θ value	2.88788e-06 (rank : 73)
Query Neighborhood Hits	412	Target Neighborhood Hits	256	Shared Neighborhood Hits	195
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

DLG2_HUMAN
NC score	0.655042 (rank : 41)	θ value	3.18553e-13 (rank : 18)
Query Neighborhood Hits	412	Target Neighborhood Hits	279	Shared Neighborhood Hits	177
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
NC score	0.654516 (rank : 42)	θ value	4.16044e-13 (rank : 19)
Query Neighborhood Hits	412	Target Neighborhood Hits	271	Shared Neighborhood Hits	177
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PARD3_MOUSE
NC score	0.651058 (rank : 43)	θ value	1.99992e-07 (rank : 61)
Query Neighborhood Hits	412	Target Neighborhood Hits	290	Shared Neighborhood Hits	170
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

GRIP1_MOUSE
NC score	0.650110 (rank : 44)	θ value	5.81887e-07 (rank : 64)
Query Neighborhood Hits	412	Target Neighborhood Hits	241	Shared Neighborhood Hits	192
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_HUMAN
NC score	0.649657 (rank : 45)	θ value	9.92553e-07 (rank : 66)
Query Neighborhood Hits	412	Target Neighborhood Hits	231	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

LNX2_MOUSE
NC score	0.649484 (rank : 46)	θ value	2.13673e-09 (rank : 42)
Query Neighborhood Hits	412	Target Neighborhood Hits	407	Shared Neighborhood Hits	178
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PARD3_HUMAN
NC score	0.648020 (rank : 47)	θ value	5.81887e-07 (rank : 65)
Query Neighborhood Hits	412	Target Neighborhood Hits	312	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

LNX1_MOUSE
NC score	0.643061 (rank : 48)	θ value	5.62301e-10 (rank : 39)
Query Neighborhood Hits	412	Target Neighborhood Hits	377	Shared Neighborhood Hits	177
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

SNTG2_HUMAN
NC score	0.642462 (rank : 49)	θ value	1.69304e-06 (rank : 70)
Query Neighborhood Hits	412	Target Neighborhood Hits	191	Shared Neighborhood Hits	175
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

LNX2_HUMAN
NC score	0.640131 (rank : 50)	θ value	5.62301e-10 (rank : 40)
Query Neighborhood Hits	412	Target Neighborhood Hits	389	Shared Neighborhood Hits	178
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

SNTB2_MOUSE
NC score	0.639351 (rank : 51)	θ value	6.87365e-08 (rank : 58)
Query Neighborhood Hits	412	Target Neighborhood Hits	181	Shared Neighborhood Hits	161
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_HUMAN
NC score	0.638327 (rank : 52)	θ value	6.87365e-08 (rank : 57)
Query Neighborhood Hits	412	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

PDZD3_MOUSE
NC score	0.636207 (rank : 53)	θ value	9.92553e-07 (rank : 67)
Query Neighborhood Hits	412	Target Neighborhood Hits	171	Shared Neighborhood Hits	164
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

MAGI2_HUMAN
NC score	0.635082 (rank : 54)	θ value	2.36244e-08 (rank : 54)
Query Neighborhood Hits	412	Target Neighborhood Hits	373	Shared Neighborhood Hits	200
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

LNX1_HUMAN
NC score	0.633247 (rank : 55)	θ value	1.47974e-10 (rank : 33)
Query Neighborhood Hits	412	Target Neighborhood Hits	379	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAGI2_MOUSE
NC score	0.632717 (rank : 56)	θ value	2.36244e-08 (rank : 55)
Query Neighborhood Hits	412	Target Neighborhood Hits	370	Shared Neighborhood Hits	209
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

SNTA1_HUMAN
NC score	0.629897 (rank : 57)	θ value	9.59137e-10 (rank : 41)
Query Neighborhood Hits	412	Target Neighborhood Hits	186	Shared Neighborhood Hits	164
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

IL16_HUMAN
NC score	0.625469 (rank : 58)	θ value	6.43352e-06 (rank : 80)
Query Neighborhood Hits	412	Target Neighborhood Hits	207	Shared Neighborhood Hits	145
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

ZO3_MOUSE
NC score	0.622344 (rank : 59)	θ value	2.52405e-10 (rank : 34)
Query Neighborhood Hits	412	Target Neighborhood Hits	224	Shared Neighborhood Hits	185
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNTA1_MOUSE
NC score	0.620230 (rank : 60)	θ value	1.80886e-08 (rank : 53)
Query Neighborhood Hits	412	Target Neighborhood Hits	170	Shared Neighborhood Hits	158
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTG2_MOUSE
NC score	0.617301 (rank : 61)	θ value	2.61198e-07 (rank : 63)
Query Neighborhood Hits	412	Target Neighborhood Hits	176	Shared Neighborhood Hits	163
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG1_MOUSE
NC score	0.609691 (rank : 62)	θ value	3.77169e-06 (rank : 75)
Query Neighborhood Hits	412	Target Neighborhood Hits	179	Shared Neighborhood Hits	166
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
NC score	0.608698 (rank : 63)	θ value	3.77169e-06 (rank : 74)
Query Neighborhood Hits	412	Target Neighborhood Hits	181	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ZO3_HUMAN
NC score	0.603813 (rank : 64)	θ value	6.87365e-08 (rank : 59)
Query Neighborhood Hits	412	Target Neighborhood Hits	219	Shared Neighborhood Hits	174
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

IL16_MOUSE
NC score	0.601600 (rank : 65)	θ value	0.000461057 (rank : 106)
Query Neighborhood Hits	412	Target Neighborhood Hits	189	Shared Neighborhood Hits	141
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTB1_HUMAN
NC score	0.597413 (rank : 66)	θ value	5.26297e-08 (rank : 56)
Query Neighborhood Hits	412	Target Neighborhood Hits	157	Shared Neighborhood Hits	149
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.596107 (rank : 67)	θ value	2.61198e-07 (rank : 62)
Query Neighborhood Hits	412	Target Neighborhood Hits	160	Shared Neighborhood Hits	148
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PZRN3_MOUSE
NC score	0.592022 (rank : 68)	θ value	3.40345e-15 (rank : 10)
Query Neighborhood Hits	412	Target Neighborhood Hits	447	Shared Neighborhood Hits	163
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.586654 (rank : 69)	θ value	1.09485e-13 (rank : 15)
Query Neighborhood Hits	412	Target Neighborhood Hits	461	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
NC score	0.579505 (rank : 70)	θ value	1.133e-10 (rank : 32)
Query Neighborhood Hits	412	Target Neighborhood Hits	438	Shared Neighborhood Hits	154
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZO2_MOUSE
NC score	0.553496 (rank : 71)	θ value	1.69304e-06 (rank : 71)
Query Neighborhood Hits	412	Target Neighborhood Hits	296	Shared Neighborhood Hits	181
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_HUMAN
NC score	0.553074 (rank : 72)	θ value	9.92553e-07 (rank : 68)
Query Neighborhood Hits	412	Target Neighborhood Hits	289	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO1_MOUSE
NC score	0.553055 (rank : 73)	θ value	3.77169e-06 (rank : 78)
Query Neighborhood Hits	412	Target Neighborhood Hits	453	Shared Neighborhood Hits	192
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_HUMAN
NC score	0.545912 (rank : 74)	θ value	3.77169e-06 (rank : 77)
Query Neighborhood Hits	412	Target Neighborhood Hits	474	Shared Neighborhood Hits	197
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

RPGF6_HUMAN
NC score	0.504695 (rank : 75)	θ value	3.40345e-15 (rank : 11)
Query Neighborhood Hits	412	Target Neighborhood Hits	266	Shared Neighborhood Hits	172
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

LAP4_HUMAN
NC score	0.498188 (rank : 76)	θ value	6.41864e-14 (rank : 14)
Query Neighborhood Hits	412	Target Neighborhood Hits	608	Shared Neighborhood Hits	214
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
NC score	0.491224 (rank : 77)	θ value	1.86753e-13 (rank : 16)
Query Neighborhood Hits	412	Target Neighborhood Hits	590	Shared Neighborhood Hits	209
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

K1849_HUMAN
NC score	0.480471 (rank : 78)	θ value	0.00509761 (rank : 138)
Query Neighborhood Hits	412	Target Neighborhood Hits	220	Shared Neighborhood Hits	148
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
NC score	0.475492 (rank : 79)	θ value	0.000602161 (rank : 108)
Query Neighborhood Hits	412	Target Neighborhood Hits	335	Shared Neighborhood Hits	166
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PDLI2_HUMAN
NC score	0.453506 (rank : 80)	θ value	0.00869519 (rank : 150)
Query Neighborhood Hits	412	Target Neighborhood Hits	245	Shared Neighborhood Hits	131
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDZK4_MOUSE
NC score	0.453400 (rank : 81)	θ value	0.00102713 (rank : 120)
Query Neighborhood Hits	412	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SYP2L_HUMAN
NC score	0.452664 (rank : 82)	θ value	3.77169e-06 (rank : 76)
Query Neighborhood Hits	412	Target Neighborhood Hits	400	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PAR6G_HUMAN
NC score	0.451158 (rank : 83)	θ value	4.92598e-06 (rank : 79)
Query Neighborhood Hits	412	Target Neighborhood Hits	159	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

AFAD_HUMAN
NC score	0.449444 (rank : 84)	θ value	2.44474e-05 (rank : 87)
Query Neighborhood Hits	412	Target Neighborhood Hits	689	Shared Neighborhood Hits	163
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

RPGF2_HUMAN
NC score	0.449374 (rank : 85)	θ value	3.52202e-12 (rank : 23)
Query Neighborhood Hits	412	Target Neighborhood Hits	242	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

PDZK4_HUMAN
NC score	0.449144 (rank : 86)	θ value	0.00102713 (rank : 119)
Query Neighborhood Hits	412	Target Neighborhood Hits	165	Shared Neighborhood Hits	122
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDLI2_MOUSE
NC score	0.449011 (rank : 87)	θ value	0.000602161 (rank : 111)
Query Neighborhood Hits	412	Target Neighborhood Hits	220	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PAR6G_MOUSE
NC score	0.444137 (rank : 88)	θ value	1.87187e-05 (rank : 86)
Query Neighborhood Hits	412	Target Neighborhood Hits	121	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PAR6B_HUMAN
NC score	0.443784 (rank : 89)	θ value	1.09739e-05 (rank : 81)
Query Neighborhood Hits	412	Target Neighborhood Hits	126	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
NC score	0.441919 (rank : 90)	θ value	2.44474e-05 (rank : 88)
Query Neighborhood Hits	412	Target Neighborhood Hits	128	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

GRASP_MOUSE
NC score	0.437492 (rank : 91)	θ value	0.00869519 (rank : 145)
Query Neighborhood Hits	412	Target Neighborhood Hits	131	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_HUMAN
NC score	0.436629 (rank : 92)	θ value	0.0148317 (rank : 158)
Query Neighborhood Hits	412	Target Neighborhood Hits	147	Shared Neighborhood Hits	121
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

DLG5_HUMAN
NC score	0.428624 (rank : 93)	θ value	1.69304e-06 (rank : 69)
Query Neighborhood Hits	412	Target Neighborhood Hits	1088	Shared Neighborhood Hits	209
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

RHPN1_MOUSE
NC score	0.424399 (rank : 94)	θ value	0.000121331 (rank : 94)
Query Neighborhood Hits	412	Target Neighborhood Hits	154	Shared Neighborhood Hits	139
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PAR6A_MOUSE
NC score	0.423343 (rank : 95)	θ value	0.00020696 (rank : 100)
Query Neighborhood Hits	412	Target Neighborhood Hits	115	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

SDCB1_MOUSE
NC score	0.422467 (rank : 96)	θ value	0.00869519 (rank : 151)
Query Neighborhood Hits	412	Target Neighborhood Hits	144	Shared Neighborhood Hits	137
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

PTN13_HUMAN
NC score	0.422000 (rank : 97)	θ value	2.79066e-09 (rank : 44)
Query Neighborhood Hits	412	Target Neighborhood Hits	471	Shared Neighborhood Hits	193
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PAR6A_HUMAN
NC score	0.421849 (rank : 98)	θ value	0.00020696 (rank : 99)
Query Neighborhood Hits	412	Target Neighborhood Hits	119	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

SDCB1_HUMAN
NC score	0.421443 (rank : 99)	θ value	0.00298849 (rank : 135)
Query Neighborhood Hits	412	Target Neighborhood Hits	150	Shared Neighborhood Hits	144
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

PTN13_MOUSE
NC score	0.416783 (rank : 100)	θ value	8.67504e-11 (rank : 31)
Query Neighborhood Hits	412	Target Neighborhood Hits	426	Shared Neighborhood Hits	190
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

APBA1_HUMAN
NC score	0.414138 (rank : 101)	θ value	0.00665767 (rank : 143)
Query Neighborhood Hits	412	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

RHPN1_HUMAN
NC score	0.410537 (rank : 102)	θ value	1.09739e-05 (rank : 82)
Query Neighborhood Hits	412	Target Neighborhood Hits	158	Shared Neighborhood Hits	133
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

APBA2_MOUSE
NC score	0.407199 (rank : 103)	θ value	0.00102713 (rank : 117)
Query Neighborhood Hits	412	Target Neighborhood Hits	219	Shared Neighborhood Hits	151
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.407106 (rank : 104)	θ value	0.00102713 (rank : 116)
Query Neighborhood Hits	412	Target Neighborhood Hits	220	Shared Neighborhood Hits	154
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

PSCBP_MOUSE
NC score	0.404082 (rank : 105)	θ value	0.0736092 (rank : 190)
Query Neighborhood Hits	412	Target Neighborhood Hits	118	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PICK1_HUMAN
NC score	0.403739 (rank : 106)	θ value	0.000786445 (rank : 114)
Query Neighborhood Hits	412	Target Neighborhood Hits	132	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

APBA3_HUMAN
NC score	0.396106 (rank : 107)	θ value	0.00509761 (rank : 137)
Query Neighborhood Hits	412	Target Neighborhood Hits	201	Shared Neighborhood Hits	138
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PICK1_MOUSE
NC score	0.392655 (rank : 108)	θ value	0.0193708 (rank : 165)
Query Neighborhood Hits	412	Target Neighborhood Hits	131	Shared Neighborhood Hits	121
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

SYNP2_MOUSE
NC score	0.388721 (rank : 109)	θ value	0.00102713 (rank : 121)
Query Neighborhood Hits	412	Target Neighborhood Hits	252	Shared Neighborhood Hits	140
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

APBA3_MOUSE
NC score	0.387506 (rank : 110)	θ value	0.00228821 (rank : 130)
Query Neighborhood Hits	412	Target Neighborhood Hits	174	Shared Neighborhood Hits	136
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

MPP4_HUMAN
NC score	0.386958 (rank : 111)	θ value	1.06291 (rank : 262)
Query Neighborhood Hits	412	Target Neighborhood Hits	205	Shared Neighborhood Hits	134
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP5_HUMAN
NC score	0.384022 (rank : 112)	θ value	0.0431538 (rank : 172)
Query Neighborhood Hits	412	Target Neighborhood Hits	231	Shared Neighborhood Hits	132
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.383004 (rank : 113)	θ value	0.0431538 (rank : 173)
Query Neighborhood Hits	412	Target Neighborhood Hits	226	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

NEB1_HUMAN
NC score	0.379316 (rank : 114)	θ value	0.00175202 (rank : 128)
Query Neighborhood Hits	412	Target Neighborhood Hits	829	Shared Neighborhood Hits	146
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

ARHGB_HUMAN
NC score	0.376299 (rank : 115)	θ value	2.21117e-06 (rank : 72)
Query Neighborhood Hits	412	Target Neighborhood Hits	375	Shared Neighborhood Hits	180
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

DVL3_HUMAN
NC score	0.376163 (rank : 116)	θ value	0.0148317 (rank : 157)
Query Neighborhood Hits	412	Target Neighborhood Hits	194	Shared Neighborhood Hits	120
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1_HUMAN
NC score	0.374895 (rank : 117)	θ value	0.0252991 (rank : 166)
Query Neighborhood Hits	412	Target Neighborhood Hits	158	Shared Neighborhood Hits	118
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL3_MOUSE
NC score	0.374327 (rank : 118)	θ value	0.0563607 (rank : 178)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	118
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL2_MOUSE
NC score	0.372175 (rank : 119)	θ value	0.00228821 (rank : 131)
Query Neighborhood Hits	412	Target Neighborhood Hits	233	Shared Neighborhood Hits	128
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_HUMAN
NC score	0.369423 (rank : 120)	θ value	0.0113563 (rank : 152)
Query Neighborhood Hits	412	Target Neighborhood Hits	223	Shared Neighborhood Hits	128
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

MPP3_MOUSE
NC score	0.368162 (rank : 121)	θ value	0.125558 (rank : 199)
Query Neighborhood Hits	412	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

DVL1_MOUSE
NC score	0.366854 (rank : 122)	θ value	0.0961366 (rank : 195)
Query Neighborhood Hits	412	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

MPP3_HUMAN
NC score	0.365563 (rank : 123)	θ value	0.0961366 (rank : 197)
Query Neighborhood Hits	412	Target Neighborhood Hits	171	Shared Neighborhood Hits	125
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

APXL_HUMAN
NC score	0.362628 (rank : 124)	θ value	0.00102713 (rank : 118)
Query Neighborhood Hits	412	Target Neighborhood Hits	553	Shared Neighborhood Hits	132
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

SYP2L_MOUSE
NC score	0.362316 (rank : 125)	θ value	4.1701e-05 (rank : 91)
Query Neighborhood Hits	412	Target Neighborhood Hits	289	Shared Neighborhood Hits	124
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

DVL1L_HUMAN
NC score	0.358608 (rank : 126)	θ value	0.0563607 (rank : 177)
Query Neighborhood Hits	412	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

SDCB2_MOUSE
NC score	0.358054 (rank : 127)	θ value	0.0431538 (rank : 176)
Query Neighborhood Hits	412	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SHAN2_HUMAN
NC score	0.357335 (rank : 128)	θ value	0.00134147 (rank : 126)
Query Neighborhood Hits	412	Target Neighborhood Hits	346	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PDLI3_HUMAN
NC score	0.354110 (rank : 129)	θ value	0.00298849 (rank : 134)
Query Neighborhood Hits	412	Target Neighborhood Hits	199	Shared Neighborhood Hits	107
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PSCBP_HUMAN
NC score	0.354044 (rank : 130)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	412	Target Neighborhood Hits	123	Shared Neighborhood Hits	113
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

NEB2_HUMAN
NC score	0.352463 (rank : 131)	θ value	0.0113563 (rank : 154)
Query Neighborhood Hits	412	Target Neighborhood Hits	883	Shared Neighborhood Hits	139
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.348449 (rank : 132)	θ value	0.0113563 (rank : 155)
Query Neighborhood Hits	412	Target Neighborhood Hits	889	Shared Neighborhood Hits	141
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDLI1_MOUSE
NC score	0.343791 (rank : 133)	θ value	0.0113563 (rank : 156)
Query Neighborhood Hits	412	Target Neighborhood Hits	213	Shared Neighborhood Hits	105
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_HUMAN
NC score	0.342463 (rank : 134)	θ value	0.00390308 (rank : 136)
Query Neighborhood Hits	412	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI4_MOUSE
NC score	0.342217 (rank : 135)	θ value	0.0193708 (rank : 164)
Query Neighborhood Hits	412	Target Neighborhood Hits	233	Shared Neighborhood Hits	114
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

ARHGC_HUMAN
NC score	0.341646 (rank : 136)	θ value	0.00020696 (rank : 97)
Query Neighborhood Hits	412	Target Neighborhood Hits	351	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

STXB4_HUMAN
NC score	0.341029 (rank : 137)	θ value	0.00134147 (rank : 127)
Query Neighborhood Hits	412	Target Neighborhood Hits	616	Shared Neighborhood Hits	110
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PDLI4_HUMAN
NC score	0.339157 (rank : 138)	θ value	0.0193708 (rank : 163)
Query Neighborhood Hits	412	Target Neighborhood Hits	245	Shared Neighborhood Hits	119
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI3_MOUSE
NC score	0.337886 (rank : 139)	θ value	0.00509761 (rank : 140)
Query Neighborhood Hits	412	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SYNP2_HUMAN
NC score	0.337454 (rank : 140)	θ value	0.00665767 (rank : 144)
Query Neighborhood Hits	412	Target Neighborhood Hits	323	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

MPP4_MOUSE
NC score	0.336811 (rank : 141)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	412	Target Neighborhood Hits	188	Shared Neighborhood Hits	116
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

ARHGC_MOUSE
NC score	0.336505 (rank : 142)	θ value	0.00035302 (rank : 103)
Query Neighborhood Hits	412	Target Neighborhood Hits	344	Shared Neighborhood Hits	158
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SDCB2_HUMAN
NC score	0.336123 (rank : 143)	θ value	1.06291 (rank : 263)
Query Neighborhood Hits	412	Target Neighborhood Hits	121	Shared Neighborhood Hits	118
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

STXB4_MOUSE
NC score	0.334230 (rank : 144)	θ value	0.00175202 (rank : 129)
Query Neighborhood Hits	412	Target Neighborhood Hits	629	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

RGS12_HUMAN
NC score	0.331810 (rank : 145)	θ value	7.1131e-05 (rank : 92)
Query Neighborhood Hits	412	Target Neighborhood Hits	333	Shared Neighborhood Hits	151
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SHAN2_MOUSE
NC score	0.321419 (rank : 146)	θ value	0.00228821 (rank : 133)
Query Neighborhood Hits	412	Target Neighborhood Hits	446	Shared Neighborhood Hits	140
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

EM55_HUMAN
NC score	0.315866 (rank : 147)	θ value	4.03905 (rank : 328)
Query Neighborhood Hits	412	Target Neighborhood Hits	228	Shared Neighborhood Hits	121
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.314798 (rank : 148)	θ value	1.38821 (rank : 269)
Query Neighborhood Hits	412	Target Neighborhood Hits	221	Shared Neighborhood Hits	118
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NOS1_HUMAN
NC score	0.296501 (rank : 149)	θ value	0.0193708 (rank : 162)
Query Neighborhood Hits	412	Target Neighborhood Hits	218	Shared Neighborhood Hits	141
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

LDB3_HUMAN
NC score	0.280146 (rank : 150)	θ value	0.000602161 (rank : 109)
Query Neighborhood Hits	412	Target Neighborhood Hits	497	Shared Neighborhood Hits	138
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
NC score	0.279310 (rank : 151)	θ value	0.00509761 (rank : 139)
Query Neighborhood Hits	412	Target Neighborhood Hits	510	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

RIMS1_HUMAN
NC score	0.274470 (rank : 152)	θ value	1.09739e-05 (rank : 83)
Query Neighborhood Hits	412	Target Neighborhood Hits	437	Shared Neighborhood Hits	138
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PDLI7_HUMAN
NC score	0.273276 (rank : 153)	θ value	0.000602161 (rank : 112)
Query Neighborhood Hits	412	Target Neighborhood Hits	547	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDLI5_HUMAN
NC score	0.268564 (rank : 154)	θ value	0.00509761 (rank : 141)
Query Neighborhood Hits	412	Target Neighborhood Hits	322	Shared Neighborhood Hits	125
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_MOUSE
NC score	0.268180 (rank : 155)	θ value	0.00134147 (rank : 123)
Query Neighborhood Hits	412	Target Neighborhood Hits	287	Shared Neighborhood Hits	119
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI7_MOUSE
NC score	0.262423 (rank : 156)	θ value	4.1701e-05 (rank : 90)
Query Neighborhood Hits	412	Target Neighborhood Hits	279	Shared Neighborhood Hits	108
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LRRC7_HUMAN
NC score	0.259442 (rank : 157)	θ value	0.000158464 (rank : 95)
Query Neighborhood Hits	412	Target Neighborhood Hits	423	Shared Neighborhood Hits	121
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MPP2_MOUSE
NC score	0.258745 (rank : 158)	θ value	1.38821 (rank : 273)
Query Neighborhood Hits	412	Target Neighborhood Hits	189	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

LRRC7_MOUSE
NC score	0.258150 (rank : 159)	θ value	0.000158464 (rank : 96)
Query Neighborhood Hits	412	Target Neighborhood Hits	416	Shared Neighborhood Hits	119
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MPP2_HUMAN
NC score	0.254595 (rank : 160)	θ value	1.38821 (rank : 272)
Query Neighborhood Hits	412	Target Neighborhood Hits	173	Shared Neighborhood Hits	90
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP6_MOUSE
NC score	0.254038 (rank : 161)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	412	Target Neighborhood Hits	187	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

NOS1_MOUSE
NC score	0.253185 (rank : 162)	θ value	0.21417 (rank : 211)
Query Neighborhood Hits	412	Target Neighborhood Hits	155	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

MPP6_HUMAN
NC score	0.250156 (rank : 163)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	412	Target Neighborhood Hits	180	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

LAP2_HUMAN
NC score	0.247173 (rank : 164)	θ value	0.00020696 (rank : 98)
Query Neighborhood Hits	412	Target Neighborhood Hits	499	Shared Neighborhood Hits	117
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SHAN1_HUMAN
NC score	0.239154 (rank : 165)	θ value	3.19293e-05 (rank : 89)
Query Neighborhood Hits	412	Target Neighborhood Hits	1041	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

LAP2_MOUSE
NC score	0.236597 (rank : 166)	θ value	0.000270298 (rank : 101)
Query Neighborhood Hits	412	Target Neighborhood Hits	482	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

GIPC1_MOUSE
NC score	0.228659 (rank : 167)	θ value	0.0961366 (rank : 196)
Query Neighborhood Hits	412	Target Neighborhood Hits	92	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

RIMS2_HUMAN
NC score	0.220831 (rank : 168)	θ value	0.00134147 (rank : 124)
Query Neighborhood Hits	412	Target Neighborhood Hits	342	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.219333 (rank : 169)	θ value	0.00134147 (rank : 125)
Query Neighborhood Hits	412	Target Neighborhood Hits	376	Shared Neighborhood Hits	116
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

GIPC1_HUMAN
NC score	0.216395 (rank : 170)	θ value	0.21417 (rank : 209)
Query Neighborhood Hits	412	Target Neighborhood Hits	91	Shared Neighborhood Hits	81
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

PCLO_MOUSE
NC score	0.215646 (rank : 171)	θ value	0.163984 (rank : 204)
Query Neighborhood Hits	412	Target Neighborhood Hits	2275	Shared Neighborhood Hits	269
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

KGUA_MOUSE
NC score	0.188212 (rank : 172)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	412	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.186177 (rank : 173)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	412	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

GIPC2_HUMAN
NC score	0.182872 (rank : 174)	θ value	1.38821 (rank : 270)
Query Neighborhood Hits	412	Target Neighborhood Hits	93	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

PTN4_HUMAN
NC score	0.182647 (rank : 175)	θ value	0.000270298 (rank : 102)
Query Neighborhood Hits	412	Target Neighborhood Hits	303	Shared Neighborhood Hits	128
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.180378 (rank : 176)	θ value	0.000786445 (rank : 115)
Query Neighborhood Hits	412	Target Neighborhood Hits	258	Shared Neighborhood Hits	117
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

LMO7_HUMAN
NC score	0.171446 (rank : 177)	θ value	0.000786445 (rank : 113)
Query Neighborhood Hits	412	Target Neighborhood Hits	507	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PDZD8_HUMAN
NC score	0.152476 (rank : 178)	θ value	0.163984 (rank : 205)
Query Neighborhood Hits	412	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

HTRA3_MOUSE
NC score	0.133317 (rank : 179)	θ value	0.47712 (rank : 225)
Query Neighborhood Hits	412	Target Neighborhood Hits	156	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

GIPC2_MOUSE
NC score	0.133294 (rank : 180)	θ value	1.06291 (rank : 258)
Query Neighborhood Hits	412	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

RGS3_MOUSE
NC score	0.133000 (rank : 181)	θ value	0.00035302 (rank : 105)
Query Neighborhood Hits	412	Target Neighborhood Hits	1621	Shared Neighborhood Hits	207
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

GIPC3_HUMAN
NC score	0.130859 (rank : 182)	θ value	0.62314 (rank : 230)
Query Neighborhood Hits	412	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

TIAM1_HUMAN
NC score	0.130049 (rank : 183)	θ value	0.0148317 (rank : 160)
Query Neighborhood Hits	412	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

GIPC3_MOUSE
NC score	0.129423 (rank : 184)	θ value	0.62314 (rank : 231)
Query Neighborhood Hits	412	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

RHPN2_MOUSE
NC score	0.128702 (rank : 185)	θ value	0.813845 (rank : 253)
Query Neighborhood Hits	412	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RGS3_HUMAN
NC score	0.127851 (rank : 186)	θ value	0.47712 (rank : 226)
Query Neighborhood Hits	412	Target Neighborhood Hits	1375	Shared Neighborhood Hits	181
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PDZD6_HUMAN
NC score	0.125216 (rank : 187)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	412	Target Neighborhood Hits	81	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

HTRA3_HUMAN
NC score	0.124402 (rank : 188)	θ value	0.47712 (rank : 224)
Query Neighborhood Hits	412	Target Neighborhood Hits	152	Shared Neighborhood Hits	65
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

PSMD9_HUMAN
NC score	0.118949 (rank : 189)	θ value	0.21417 (rank : 212)
Query Neighborhood Hits	412	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

TIAM1_MOUSE
NC score	0.102663 (rank : 190)	θ value	0.0252991 (rank : 168)
Query Neighborhood Hits	412	Target Neighborhood Hits	205	Shared Neighborhood Hits	52
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

CSKP_HUMAN
NC score	0.102609 (rank : 191)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	412	Target Neighborhood Hits	1022	Shared Neighborhood Hits	122
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

EAF1_MOUSE
NC score	0.100639 (rank : 192)	θ value	0.00035302 (rank : 104)
Query Neighborhood Hits	412	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

CSKP_MOUSE
NC score	0.100084 (rank : 193)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	412	Target Neighborhood Hits	1027	Shared Neighborhood Hits	122
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

PRRT3_HUMAN
NC score	0.097844 (rank : 194)	θ value	0.0961366 (rank : 198)
Query Neighborhood Hits	412	Target Neighborhood Hits	998	Shared Neighborhood Hits	135
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

EAF1_HUMAN
NC score	0.097794 (rank : 195)	θ value	0.000602161 (rank : 107)
Query Neighborhood Hits	412	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

HTRA1_HUMAN
NC score	0.097197 (rank : 196)	θ value	0.813845 (rank : 247)
Query Neighborhood Hits	412	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

BCL9_HUMAN
NC score	0.096140 (rank : 197)	θ value	0.0193708 (rank : 161)
Query Neighborhood Hits	412	Target Neighborhood Hits	1008	Shared Neighborhood Hits	143
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MUC1_HUMAN
NC score	0.095747 (rank : 198)	θ value	0.00134147 (rank : 122)
Query Neighborhood Hits	412	Target Neighborhood Hits	975	Shared Neighborhood Hits	139
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

HTRA1_MOUSE
NC score	0.094398 (rank : 199)	θ value	0.813845 (rank : 248)
Query Neighborhood Hits	412	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

CNKR2_MOUSE
NC score	0.093724 (rank : 200)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	412	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.093638 (rank : 201)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	412	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

MUC7_HUMAN
NC score	0.091381 (rank : 202)	θ value	0.0431538 (rank : 174)
Query Neighborhood Hits	412	Target Neighborhood Hits	538	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

CAR11_HUMAN
NC score	0.091370 (rank : 203)	θ value	0.279714 (rank : 214)
Query Neighborhood Hits	412	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

GSCR1_HUMAN
NC score	0.090703 (rank : 204)	θ value	0.163984 (rank : 203)
Query Neighborhood Hits	412	Target Neighborhood Hits	674	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PSMD9_MOUSE
NC score	0.090382 (rank : 205)	θ value	0.813845 (rank : 251)
Query Neighborhood Hits	412	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

PRAX_MOUSE
NC score	0.088442 (rank : 206)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	412	Target Neighborhood Hits	199	Shared Neighborhood Hits	54
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SRRM2_MOUSE
NC score	0.087207 (rank : 207)	θ value	4.03905 (rank : 341)
Query Neighborhood Hits	412	Target Neighborhood Hits	1470	Shared Neighborhood Hits	141
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

HTRA4_HUMAN
NC score	0.086617 (rank : 208)	θ value	1.06291 (rank : 259)
Query Neighborhood Hits	412	Target Neighborhood Hits	119	Shared Neighborhood Hits	45
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

BAT2_HUMAN
NC score	0.083373 (rank : 209)	θ value	1.38821 (rank : 268)
Query Neighborhood Hits	412	Target Neighborhood Hits	931	Shared Neighborhood Hits	135
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MAST4_HUMAN
NC score	0.083343 (rank : 210)	θ value	0.000602161 (rank : 110)
Query Neighborhood Hits	412	Target Neighborhood Hits	1804	Shared Neighborhood Hits	217
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RNF41_MOUSE
NC score	0.081315 (rank : 211)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	412	Target Neighborhood Hits	224	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.081140 (rank : 212)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	412	Target Neighborhood Hits	226	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

PTN23_MOUSE
NC score	0.078410 (rank : 213)	θ value	0.00509761 (rank : 142)
Query Neighborhood Hits	412	Target Neighborhood Hits	726	Shared Neighborhood Hits	75
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RHPN2_HUMAN
NC score	0.077262 (rank : 214)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	412	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

WIRE_MOUSE
NC score	0.076268 (rank : 215)	θ value	0.62314 (rank : 241)
Query Neighborhood Hits	412	Target Neighborhood Hits	310	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

PRB4S_HUMAN
NC score	0.075957 (rank : 216)	θ value	0.0330416 (rank : 170)
Query Neighborhood Hits	412	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

WIRE_HUMAN
NC score	0.075574 (rank : 217)	θ value	1.38821 (rank : 278)
Query Neighborhood Hits	412	Target Neighborhood Hits	329	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

TCOF_MOUSE
NC score	0.074613 (rank : 218)	θ value	0.279714 (rank : 218)
Query Neighborhood Hits	412	Target Neighborhood Hits	471	Shared Neighborhood Hits	57
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

LPP_HUMAN
NC score	0.074402 (rank : 219)	θ value	0.0736092 (rank : 186)
Query Neighborhood Hits	412	Target Neighborhood Hits	775	Shared Neighborhood Hits	118
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

SI1L2_HUMAN
NC score	0.074292 (rank : 220)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	412	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

OGFR_HUMAN
NC score	0.073811 (rank : 221)	θ value	0.62314 (rank : 237)
Query Neighborhood Hits	412	Target Neighborhood Hits	1582	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MAST3_HUMAN
NC score	0.073424 (rank : 222)	θ value	0.00228821 (rank : 132)
Query Neighborhood Hits	412	Target Neighborhood Hits	1128	Shared Neighborhood Hits	145
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

PRR12_HUMAN
NC score	0.073411 (rank : 223)	θ value	4.03905 (rank : 333)
Query Neighborhood Hits	412	Target Neighborhood Hits	460	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

NACAM_MOUSE
NC score	0.072794 (rank : 224)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	412	Target Neighborhood Hits	1866	Shared Neighborhood Hits	170
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SI1L2_MOUSE
NC score	0.072551 (rank : 225)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	412	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

MAST2_HUMAN
NC score	0.072072 (rank : 226)	θ value	0.0113563 (rank : 153)
Query Neighborhood Hits	412	Target Neighborhood Hits	1189	Shared Neighborhood Hits	145
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST1_MOUSE
NC score	0.071877 (rank : 227)	θ value	0.00869519 (rank : 149)
Query Neighborhood Hits	412	Target Neighborhood Hits	1123	Shared Neighborhood Hits	137
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SRRM1_MOUSE
NC score	0.071709 (rank : 228)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	412	Target Neighborhood Hits	966	Shared Neighborhood Hits	122
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MAST1_HUMAN
NC score	0.071471 (rank : 229)	θ value	0.00869519 (rank : 148)
Query Neighborhood Hits	412	Target Neighborhood Hits	1146	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SRRM2_HUMAN
NC score	0.071294 (rank : 230)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	412	Target Neighborhood Hits	1296	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PCLO_HUMAN
NC score	0.071005 (rank : 231)	θ value	3.0926 (rank : 317)
Query Neighborhood Hits	412	Target Neighborhood Hits	2046	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MAST2_MOUSE
NC score	0.070462 (rank : 232)	θ value	0.0252991 (rank : 167)
Query Neighborhood Hits	412	Target Neighborhood Hits	1110	Shared Neighborhood Hits	145
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

GGN_MOUSE
NC score	0.070042 (rank : 233)	θ value	0.0736092 (rank : 185)
Query Neighborhood Hits	412	Target Neighborhood Hits	311	Shared Neighborhood Hits	46
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MY18A_MOUSE
NC score	0.069640 (rank : 234)	θ value	1.81305 (rank : 284)
Query Neighborhood Hits	412	Target Neighborhood Hits	1989	Shared Neighborhood Hits	165
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

BAT2_MOUSE
NC score	0.069164 (rank : 235)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	412	Target Neighborhood Hits	947	Shared Neighborhood Hits	134
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SI1L1_HUMAN
NC score	0.068903 (rank : 236)	θ value	1.81305 (rank : 286)
Query Neighborhood Hits	412	Target Neighborhood Hits	162	Shared Neighborhood Hits	43
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

PTN23_HUMAN
NC score	0.068891 (rank : 237)	θ value	1.38821 (rank : 276)
Query Neighborhood Hits	412	Target Neighborhood Hits	646	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

BCL9_MOUSE
NC score	0.068612 (rank : 238)	θ value	5.27518 (rank : 348)
Query Neighborhood Hits	412	Target Neighborhood Hits	770	Shared Neighborhood Hits	112
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

WASIP_HUMAN
NC score	0.067474 (rank : 239)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	412	Target Neighborhood Hits	458	Shared Neighborhood Hits	70
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PRAX_HUMAN
NC score	0.067447 (rank : 240)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	412	Target Neighborhood Hits	215	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PREX1_HUMAN
NC score	0.067247 (rank : 241)	θ value	0.0736092 (rank : 189)
Query Neighborhood Hits	412	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

SI1L1_MOUSE
NC score	0.066595 (rank : 242)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	412	Target Neighborhood Hits	189	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

CS007_HUMAN
NC score	0.065766 (rank : 243)	θ value	0.0961366 (rank : 194)
Query Neighborhood Hits	412	Target Neighborhood Hits	401	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

GGN_HUMAN
NC score	0.064444 (rank : 244)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	412	Target Neighborhood Hits	269	Shared Neighborhood Hits	48
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CAR14_HUMAN
NC score	0.064402 (rank : 245)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	412	Target Neighborhood Hits	449	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

SON_HUMAN
NC score	0.064293 (rank : 246)	θ value	1.06291 (rank : 265)
Query Neighborhood Hits	412	Target Neighborhood Hits	1568	Shared Neighborhood Hits	156
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SF3A2_MOUSE
NC score	0.064250 (rank : 247)	θ value	1.06291 (rank : 264)
Query Neighborhood Hits	412	Target Neighborhood Hits	247	Shared Neighborhood Hits	43
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SC24C_HUMAN
NC score	0.064208 (rank : 248)	θ value	0.163984 (rank : 206)
Query Neighborhood Hits	412	Target Neighborhood Hits	662	Shared Neighborhood Hits	98
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CPSF6_MOUSE
NC score	0.064012 (rank : 249)	θ value	0.813845 (rank : 245)
Query Neighborhood Hits	412	Target Neighborhood Hits	356	Shared Neighborhood Hits	46
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

MDC1_MOUSE
NC score	0.063995 (rank : 250)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	412	Target Neighborhood Hits	998	Shared Neighborhood Hits	130
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SIPA1_HUMAN
NC score	0.063760 (rank : 251)	θ value	0.279714 (rank : 217)
Query Neighborhood Hits	412	Target Neighborhood Hits	250	Shared Neighborhood Hits	42
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

BSN_MOUSE
NC score	0.063718 (rank : 252)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	412	Target Neighborhood Hits	2057	Shared Neighborhood Hits	178
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

FA47B_HUMAN
NC score	0.063418 (rank : 253)	θ value	0.0563607 (rank : 179)
Query Neighborhood Hits	412	Target Neighborhood Hits	431	Shared Neighborhood Hits	75
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

BAG3_MOUSE
NC score	0.063157 (rank : 254)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	412	Target Neighborhood Hits	513	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

SI1L3_HUMAN
NC score	0.062944 (rank : 255)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	412	Target Neighborhood Hits	305	Shared Neighborhood Hits	75
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

MY18A_HUMAN
NC score	0.062805 (rank : 256)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	412	Target Neighborhood Hits	1929	Shared Neighborhood Hits	162
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CPSF6_HUMAN
NC score	0.062461 (rank : 257)	θ value	0.813845 (rank : 244)
Query Neighborhood Hits	412	Target Neighborhood Hits	359	Shared Neighborhood Hits	44
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

MLL3_HUMAN
NC score	0.062369 (rank : 258)	θ value	1.06291 (rank : 261)
Query Neighborhood Hits	412	Target Neighborhood Hits	1644	Shared Neighborhood Hits	151
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CS007_MOUSE
NC score	0.062117 (rank : 259)	θ value	0.21417 (rank : 208)
Query Neighborhood Hits	412	Target Neighborhood Hits	464	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

SYN1_HUMAN
NC score	0.062020 (rank : 260)	θ value	0.21417 (rank : 213)
Query Neighborhood Hits	412	Target Neighborhood Hits	419	Shared Neighborhood Hits	70
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

CBP_MOUSE
NC score	0.061822 (rank : 261)	θ value	0.62314 (rank : 228)
Query Neighborhood Hits	412	Target Neighborhood Hits	1051	Shared Neighborhood Hits	126
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SF3A2_HUMAN
NC score	0.061312 (rank : 262)	θ value	1.81305 (rank : 285)
Query Neighborhood Hits	412	Target Neighborhood Hits	263	Shared Neighborhood Hits	39
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WASIP_MOUSE
NC score	0.061251 (rank : 263)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	412	Target Neighborhood Hits	392	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

YAP1_MOUSE
NC score	0.060280 (rank : 264)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	412	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

TCOF_HUMAN
NC score	0.060193 (rank : 265)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	412	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

IRS2_HUMAN
NC score	0.059649 (rank : 266)	θ value	0.0148317 (rank : 159)
Query Neighborhood Hits	412	Target Neighborhood Hits	262	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MDC1_HUMAN
NC score	0.059519 (rank : 267)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	412	Target Neighborhood Hits	1446	Shared Neighborhood Hits	144
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

LRRC1_MOUSE
NC score	0.059294 (rank : 268)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	412	Target Neighborhood Hits	281	Shared Neighborhood Hits	6
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

CN155_HUMAN
NC score	0.059281 (rank : 269)	θ value	2.36792 (rank : 292)
Query Neighborhood Hits	412	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

SYN1_MOUSE
NC score	0.059179 (rank : 270)	θ value	0.125558 (rank : 200)
Query Neighborhood Hits	412	Target Neighborhood Hits	363	Shared Neighborhood Hits	56
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

LRRC1_HUMAN
NC score	0.058987 (rank : 271)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	412	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

BSN_HUMAN
NC score	0.058697 (rank : 272)	θ value	4.03905 (rank : 326)
Query Neighborhood Hits	412	Target Neighborhood Hits	1537	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

YAP1_HUMAN
NC score	0.058615 (rank : 273)	θ value	0.62314 (rank : 242)
Query Neighborhood Hits	412	Target Neighborhood Hits	173	Shared Neighborhood Hits	24
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PRP2_MOUSE
NC score	0.058188 (rank : 274)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	412	Target Neighborhood Hits	347	Shared Neighborhood Hits	50
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP1_HUMAN
NC score	0.057970 (rank : 275)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	412	Target Neighborhood Hits	385	Shared Neighborhood Hits	56
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CAR14_MOUSE
NC score	0.057721 (rank : 276)	θ value	6.88961 (rank : 371)
Query Neighborhood Hits	412	Target Neighborhood Hits	526	Shared Neighborhood Hits	37
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

NCOA6_HUMAN
NC score	0.057628 (rank : 277)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	412	Target Neighborhood Hits	1202	Shared Neighborhood Hits	132
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RERE_MOUSE
NC score	0.057401 (rank : 278)	θ value	0.813845 (rank : 252)
Query Neighborhood Hits	412	Target Neighborhood Hits	785	Shared Neighborhood Hits	98
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CS016_HUMAN
NC score	0.057282 (rank : 279)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	412	Target Neighborhood Hits	310	Shared Neighborhood Hits	56
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SRRM1_HUMAN
NC score	0.057165 (rank : 280)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	412	Target Neighborhood Hits	690	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

BAG3_HUMAN
NC score	0.057137 (rank : 281)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	412	Target Neighborhood Hits	314	Shared Neighborhood Hits	61
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

PRB3_HUMAN
NC score	0.056642 (rank : 282)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	412	Target Neighborhood Hits	318	Shared Neighborhood Hits	45
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

NFH_MOUSE
NC score	0.056437 (rank : 283)	θ value	0.0330416 (rank : 169)
Query Neighborhood Hits	412	Target Neighborhood Hits	2247	Shared Neighborhood Hits	159
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ENAH_MOUSE
NC score	0.056157 (rank : 284)	θ value	8.99809 (rank : 396)
Query Neighborhood Hits	412	Target Neighborhood Hits	919	Shared Neighborhood Hits	89
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GRIN1_MOUSE
NC score	0.055337 (rank : 285)	θ value	0.21417 (rank : 210)
Query Neighborhood Hits	412	Target Neighborhood Hits	337	Shared Neighborhood Hits	53
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NCOR2_HUMAN
NC score	0.055081 (rank : 286)	θ value	0.0431538 (rank : 175)
Query Neighborhood Hits	412	Target Neighborhood Hits	870	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CBP_HUMAN
NC score	0.054667 (rank : 287)	θ value	5.27518 (rank : 351)
Query Neighborhood Hits	412	Target Neighborhood Hits	941	Shared Neighborhood Hits	124
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SYNPO_HUMAN
NC score	0.054144 (rank : 288)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	412	Target Neighborhood Hits	281	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SELPL_MOUSE
NC score	0.054067 (rank : 289)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	412	Target Neighborhood Hits	588	Shared Neighborhood Hits	86
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

HTRA2_HUMAN
NC score	0.053721 (rank : 290)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	412	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

CCNK_MOUSE
NC score	0.053541 (rank : 291)	θ value	0.47712 (rank : 221)
Query Neighborhood Hits	412	Target Neighborhood Hits	350	Shared Neighborhood Hits	52
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

TGON2_HUMAN
NC score	0.053385 (rank : 292)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	412	Target Neighborhood Hits	1037	Shared Neighborhood Hits	96
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

YLPM1_HUMAN
NC score	0.053382 (rank : 293)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	412	Target Neighborhood Hits	670	Shared Neighborhood Hits	90
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SYNPO_MOUSE
NC score	0.053235 (rank : 294)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	412	Target Neighborhood Hits	242	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

T22D4_HUMAN
NC score	0.053208 (rank : 295)	θ value	0.47712 (rank : 227)
Query Neighborhood Hits	412	Target Neighborhood Hits	403	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

SAV1_HUMAN
NC score	0.052934 (rank : 296)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	412	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
NC score	0.052872 (rank : 297)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	412	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

CRTC1_HUMAN
NC score	0.052619 (rank : 298)	θ value	0.163984 (rank : 201)
Query Neighborhood Hits	412	Target Neighborhood Hits	319	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ZYX_HUMAN
NC score	0.052334 (rank : 299)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	412	Target Neighborhood Hits	387	Shared Neighborhood Hits	56
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

RERE_HUMAN
NC score	0.052027 (rank : 300)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	412	Target Neighborhood Hits	779	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

MBD6_HUMAN
NC score	0.052006 (rank : 301)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	412	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

RPGF1_HUMAN
NC score	0.051725 (rank : 302)	θ value	1.38821 (rank : 277)
Query Neighborhood Hits	412	Target Neighborhood Hits	262	Shared Neighborhood Hits	46
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

ARI1A_HUMAN
NC score	0.051640 (rank : 303)	θ value	6.88961 (rank : 370)
Query Neighborhood Hits	412	Target Neighborhood Hits	787	Shared Neighborhood Hits	97
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATN1_HUMAN
NC score	0.051294 (rank : 304)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	412	Target Neighborhood Hits	676	Shared Neighborhood Hits	83
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

WASL_MOUSE
NC score	0.051057 (rank : 305)	θ value	4.03905 (rank : 343)
Query Neighborhood Hits	412	Target Neighborhood Hits	339	Shared Neighborhood Hits	56
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

HTRA2_MOUSE
NC score	0.050090 (rank : 306)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	412	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

SSBP4_HUMAN
NC score	0.049812 (rank : 307)	θ value	0.365318 (rank : 220)
Query Neighborhood Hits	412	Target Neighborhood Hits	753	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SIPA1_MOUSE
NC score	0.048787 (rank : 308)	θ value	0.813845 (rank : 254)
Query Neighborhood Hits	412	Target Neighborhood Hits	158	Shared Neighborhood Hits	25
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

K1802_MOUSE
NC score	0.048536 (rank : 309)	θ value	2.36792 (rank : 296)
Query Neighborhood Hits	412	Target Neighborhood Hits	1596	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CI079_HUMAN
NC score	0.048148 (rank : 310)	θ value	0.62314 (rank : 229)
Query Neighborhood Hits	412	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

LCP2_HUMAN
NC score	0.047639 (rank : 311)	θ value	0.62314 (rank : 235)
Query Neighborhood Hits	412	Target Neighborhood Hits	531	Shared Neighborhood Hits	74
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MTSS1_MOUSE
NC score	0.047542 (rank : 312)	θ value	3.0926 (rank : 315)
Query Neighborhood Hits	412	Target Neighborhood Hits	592	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CDN1C_MOUSE
NC score	0.047042 (rank : 313)	θ value	0.0961366 (rank : 193)
Query Neighborhood Hits	412	Target Neighborhood Hits	161	Shared Neighborhood Hits	18
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

WASL_HUMAN
NC score	0.046928 (rank : 314)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	412	Target Neighborhood Hits	312	Shared Neighborhood Hits	49
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MLL2_HUMAN
NC score	0.046463 (rank : 315)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	412	Target Neighborhood Hits	1788	Shared Neighborhood Hits	144
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

IF4G1_HUMAN
NC score	0.045287 (rank : 316)	θ value	3.0926 (rank : 312)
Query Neighborhood Hits	412	Target Neighborhood Hits	347	Shared Neighborhood Hits	50
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MLL4_HUMAN
NC score	0.045171 (rank : 317)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	412	Target Neighborhood Hits	722	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

IF4G3_MOUSE
NC score	0.045168 (rank : 318)	θ value	0.279714 (rank : 215)
Query Neighborhood Hits	412	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

FMN2_HUMAN
NC score	0.045131 (rank : 319)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	412	Target Neighborhood Hits	484	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

CTDP1_HUMAN
NC score	0.045064 (rank : 320)	θ value	1.81305 (rank : 282)
Query Neighborhood Hits	412	Target Neighborhood Hits	416	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

GA2L3_HUMAN
NC score	0.044812 (rank : 321)	θ value	0.0563607 (rank : 180)
Query Neighborhood Hits	412	Target Neighborhood Hits	189	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

BCAR1_HUMAN
NC score	0.043718 (rank : 322)	θ value	1.06291 (rank : 256)
Query Neighborhood Hits	412	Target Neighborhood Hits	554	Shared Neighborhood Hits	82
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MTSS1_HUMAN
NC score	0.043374 (rank : 323)	θ value	1.38821 (rank : 274)
Query Neighborhood Hits	412	Target Neighborhood Hits	504	Shared Neighborhood Hits	68
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

IF4G3_HUMAN
NC score	0.042660 (rank : 324)	θ value	0.0563607 (rank : 182)
Query Neighborhood Hits	412	Target Neighborhood Hits	247	Shared Neighborhood Hits	30
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PRR8_HUMAN
NC score	0.042490 (rank : 325)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	412	Target Neighborhood Hits	217	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

IWS1_MOUSE
NC score	0.041716 (rank : 326)	θ value	4.03905 (rank : 329)
Query Neighborhood Hits	412	Target Neighborhood Hits	1258	Shared Neighborhood Hits	110
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LIMK1_HUMAN
NC score	0.041621 (rank : 327)	θ value	0.00869519 (rank : 146)
Query Neighborhood Hits	412	Target Neighborhood Hits	1005	Shared Neighborhood Hits	83
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

TCRG1_MOUSE
NC score	0.041190 (rank : 328)	θ value	0.0736092 (rank : 191)
Query Neighborhood Hits	412	Target Neighborhood Hits	947	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

AFF2_MOUSE
NC score	0.040474 (rank : 329)	θ value	0.0961366 (rank : 192)
Query Neighborhood Hits	412	Target Neighborhood Hits	225	Shared Neighborhood Hits	27
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

K1802_HUMAN
NC score	0.040360 (rank : 330)	θ value	0.62314 (rank : 233)
Query Neighborhood Hits	412	Target Neighborhood Hits	1378	Shared Neighborhood Hits	123
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SGIP1_HUMAN
NC score	0.040201 (rank : 331)	θ value	3.0926 (rank : 319)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

LIMK1_MOUSE
NC score	0.039716 (rank : 332)	θ value	0.00869519 (rank : 147)
Query Neighborhood Hits	412	Target Neighborhood Hits	1008	Shared Neighborhood Hits	81
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

ENAH_HUMAN
NC score	0.037883 (rank : 333)	θ value	6.88961 (rank : 373)
Query Neighborhood Hits	412	Target Neighborhood Hits	784	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

WBS14_HUMAN
NC score	0.037882 (rank : 334)	θ value	0.62314 (rank : 240)
Query Neighborhood Hits	412	Target Neighborhood Hits	273	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ZAR1_MOUSE
NC score	0.037624 (rank : 335)	θ value	1.81305 (rank : 290)
Query Neighborhood Hits	412	Target Neighborhood Hits	254	Shared Neighborhood Hits	34
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

BCAR1_MOUSE
NC score	0.036629 (rank : 336)	θ value	1.81305 (rank : 279)
Query Neighborhood Hits	412	Target Neighborhood Hits	438	Shared Neighborhood Hits	65
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PPRB_HUMAN
NC score	0.036565 (rank : 337)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	412	Target Neighborhood Hits	311	Shared Neighborhood Hits	38
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

ENAM_MOUSE
NC score	0.036445 (rank : 338)	θ value	1.06291 (rank : 257)
Query Neighborhood Hits	412	Target Neighborhood Hits	229	Shared Neighborhood Hits	41
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

RTN4_HUMAN
NC score	0.036428 (rank : 339)	θ value	0.279714 (rank : 216)
Query Neighborhood Hits	412	Target Neighborhood Hits	357	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TCRG1_HUMAN
NC score	0.036111 (rank : 340)	θ value	0.813845 (rank : 255)
Query Neighborhood Hits	412	Target Neighborhood Hits	929	Shared Neighborhood Hits	58
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

MAGD4_HUMAN
NC score	0.035359 (rank : 341)	θ value	0.0736092 (rank : 187)
Query Neighborhood Hits	412	Target Neighborhood Hits	338	Shared Neighborhood Hits	47
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

PELP1_HUMAN
NC score	0.035164 (rank : 342)	θ value	4.03905 (rank : 332)
Query Neighborhood Hits	412	Target Neighborhood Hits	596	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

FMNL_HUMAN
NC score	0.033990 (rank : 343)	θ value	8.99809 (rank : 399)
Query Neighborhood Hits	412	Target Neighborhood Hits	529	Shared Neighborhood Hits	53
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GATA3_HUMAN
NC score	0.033881 (rank : 344)	θ value	0.0563607 (rank : 181)
Query Neighborhood Hits	412	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P23771, Q96J16	Gene names	GATA3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

WASF4_HUMAN
NC score	0.033347 (rank : 345)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	412	Target Neighborhood Hits	282	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

PER3_HUMAN
NC score	0.033270 (rank : 346)	θ value	2.36792 (rank : 298)
Query Neighborhood Hits	412	Target Neighborhood Hits	479	Shared Neighborhood Hits	62
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

GATA3_MOUSE
NC score	0.033062 (rank : 347)	θ value	0.0736092 (rank : 184)
Query Neighborhood Hits	412	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	P23772	Gene names	Gata3, Gata-3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

CBL_MOUSE
NC score	0.032382 (rank : 348)	θ value	5.27518 (rank : 350)
Query Neighborhood Hits	412	Target Neighborhood Hits	426	Shared Neighborhood Hits	47
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TGON1_MOUSE
NC score	0.032145 (rank : 349)	θ value	1.06291 (rank : 266)
Query Neighborhood Hits	412	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TAB3_MOUSE
NC score	0.031859 (rank : 350)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	412	Target Neighborhood Hits	273	Shared Neighborhood Hits	43
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

CITE4_MOUSE
NC score	0.030970 (rank : 351)	θ value	2.36792 (rank : 291)
Query Neighborhood Hits	412	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

MINT_HUMAN
NC score	0.030769 (rank : 352)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	412	Target Neighborhood Hits	1291	Shared Neighborhood Hits	91
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

LR37A_HUMAN
NC score	0.030640 (rank : 353)	θ value	0.62314 (rank : 236)
Query Neighborhood Hits	412	Target Neighborhood Hits	720	Shared Neighborhood Hits	66
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

ALO17_HUMAN
NC score	0.030513 (rank : 354)	θ value	3.0926 (rank : 300)
Query Neighborhood Hits	412	Target Neighborhood Hits	317	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

HSF1_MOUSE
NC score	0.029775 (rank : 355)	θ value	0.813845 (rank : 246)
Query Neighborhood Hits	412	Target Neighborhood Hits	267	Shared Neighborhood Hits	45
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

FHOD1_MOUSE
NC score	0.029419 (rank : 356)	θ value	3.0926 (rank : 307)
Query Neighborhood Hits	412	Target Neighborhood Hits	217	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

EPN3_MOUSE
NC score	0.029392 (rank : 357)	θ value	1.81305 (rank : 283)
Query Neighborhood Hits	412	Target Neighborhood Hits	312	Shared Neighborhood Hits	45
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

ABI2_HUMAN
NC score	0.028070 (rank : 358)	θ value	6.88961 (rank : 368)
Query Neighborhood Hits	412	Target Neighborhood Hits	350	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CRSP7_HUMAN
NC score	0.027897 (rank : 359)	θ value	3.0926 (rank : 304)
Query Neighborhood Hits	412	Target Neighborhood Hits	247	Shared Neighborhood Hits	31
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CD248_HUMAN
NC score	0.027834 (rank : 360)	θ value	0.47712 (rank : 222)
Query Neighborhood Hits	412	Target Neighborhood Hits	679	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TGON2_MOUSE
NC score	0.027746 (rank : 361)	θ value	3.0926 (rank : 321)
Query Neighborhood Hits	412	Target Neighborhood Hits	277	Shared Neighborhood Hits	29
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

AXN1_MOUSE
NC score	0.027647 (rank : 362)	θ value	4.03905 (rank : 325)
Query Neighborhood Hits	412	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

EAN57_HUMAN
NC score	0.027509 (rank : 363)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	412	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

DOK7_MOUSE
NC score	0.026970 (rank : 364)	θ value	3.0926 (rank : 306)
Query Neighborhood Hits	412	Target Neighborhood Hits	169	Shared Neighborhood Hits	31
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

FMNL_MOUSE
NC score	0.026895 (rank : 365)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	412	Target Neighborhood Hits	428	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

DIAP1_MOUSE
NC score	0.026543 (rank : 366)	θ value	8.99809 (rank : 395)
Query Neighborhood Hits	412	Target Neighborhood Hits	839	Shared Neighborhood Hits	54
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

PO6F2_HUMAN
NC score	0.026389 (rank : 367)	θ value	0.0736092 (rank : 188)
Query Neighborhood Hits	412	Target Neighborhood Hits	618	Shared Neighborhood Hits	52
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

ANTR1_MOUSE
NC score	0.026223 (rank : 368)	θ value	3.0926 (rank : 302)
Query Neighborhood Hits	412	Target Neighborhood Hits	143	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ANTR1_HUMAN
NC score	0.025761 (rank : 369)	θ value	3.0926 (rank : 301)
Query Neighborhood Hits	412	Target Neighborhood Hits	128	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

AF10_HUMAN
NC score	0.025451 (rank : 370)	θ value	0.21417 (rank : 207)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

TXLNB_HUMAN
NC score	0.024316 (rank : 371)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	412	Target Neighborhood Hits	912	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

DIAP2_MOUSE
NC score	0.023921 (rank : 372)	θ value	2.36792 (rank : 293)
Query Neighborhood Hits	412	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

AF10_MOUSE
NC score	0.023794 (rank : 373)	θ value	0.813845 (rank : 243)
Query Neighborhood Hits	412	Target Neighborhood Hits	182	Shared Neighborhood Hits	14
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AKA10_MOUSE
NC score	0.023054 (rank : 374)	θ value	5.27518 (rank : 345)
Query Neighborhood Hits	412	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

FOXN4_HUMAN
NC score	0.021934 (rank : 375)	θ value	0.47712 (rank : 223)
Query Neighborhood Hits	412	Target Neighborhood Hits	248	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

ANR11_HUMAN
NC score	0.021683 (rank : 376)	θ value	5.27518 (rank : 346)
Query Neighborhood Hits	412	Target Neighborhood Hits	1289	Shared Neighborhood Hits	94
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

EVL_MOUSE
NC score	0.021535 (rank : 377)	θ value	6.88961 (rank : 374)
Query Neighborhood Hits	412	Target Neighborhood Hits	203	Shared Neighborhood Hits	30
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

BCOR_HUMAN
NC score	0.021373 (rank : 378)	θ value	1.81305 (rank : 280)
Query Neighborhood Hits	412	Target Neighborhood Hits	609	Shared Neighborhood Hits	52
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

EVL_HUMAN
NC score	0.021145 (rank : 379)	θ value	5.27518 (rank : 355)
Query Neighborhood Hits	412	Target Neighborhood Hits	260	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

MEGF9_MOUSE
NC score	0.020952 (rank : 380)	θ value	4.03905 (rank : 330)
Query Neighborhood Hits	412	Target Neighborhood Hits	896	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

T240L_MOUSE
NC score	0.020375 (rank : 381)	θ value	1.81305 (rank : 288)
Query Neighborhood Hits	412	Target Neighborhood Hits	143	Shared Neighborhood Hits	23
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

SEZ6L_HUMAN
NC score	0.020281 (rank : 382)	θ value	0.62314 (rank : 238)
Query Neighborhood Hits	412	Target Neighborhood Hits	289	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

DAAM1_HUMAN
NC score	0.020234 (rank : 383)	θ value	3.0926 (rank : 305)
Query Neighborhood Hits	412	Target Neighborhood Hits	483	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

IFI5_MOUSE
NC score	0.020215 (rank : 384)	θ value	0.365318 (rank : 219)
Query Neighborhood Hits	412	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q08619	Gene names	Ifi205
Domain Architecture
Description	Interferon-activable protein 205 (IFI-205) (D3 protein).

SMRC1_MOUSE
NC score	0.019692 (rank : 385)	θ value	4.03905 (rank : 340)
Query Neighborhood Hits	412	Target Neighborhood Hits	459	Shared Neighborhood Hits	40
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

PAF49_MOUSE
NC score	0.019386 (rank : 386)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	412	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

HCN2_HUMAN
NC score	0.019121 (rank : 387)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	412	Target Neighborhood Hits	369	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

NIBL_HUMAN
NC score	0.018988 (rank : 388)	θ value	1.38821 (rank : 275)
Query Neighborhood Hits	412	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

FOXP4_HUMAN
NC score	0.017851 (rank : 389)	θ value	0.163984 (rank : 202)
Query Neighborhood Hits	412	Target Neighborhood Hits	246	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

ADDB_MOUSE
NC score	0.017739 (rank : 390)	θ value	5.27518 (rank : 344)
Query Neighborhood Hits	412	Target Neighborhood Hits	574	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

RHBD3_HUMAN
NC score	0.017579 (rank : 391)	θ value	3.0926 (rank : 318)
Query Neighborhood Hits	412	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3P4, Q6I9X3, Q9UGQ7	Gene names	RHBDD3, C22orf3
Domain Architecture
Description	Rhomboid domain-containing protein 3.

PHC3_MOUSE
NC score	0.016606 (rank : 392)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	412	Target Neighborhood Hits	194	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

ABI2_MOUSE
NC score	0.016546 (rank : 393)	θ value	6.88961 (rank : 369)
Query Neighborhood Hits	412	Target Neighborhood Hits	266	Shared Neighborhood Hits	25
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

JHD3B_MOUSE
NC score	0.016276 (rank : 394)	θ value	2.36792 (rank : 295)
Query Neighborhood Hits	412	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

KI13B_HUMAN
NC score	0.016272 (rank : 395)	θ value	0.62314 (rank : 234)
Query Neighborhood Hits	412	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

ZCH11_HUMAN
NC score	0.016224 (rank : 396)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	412	Target Neighborhood Hits	278	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ZN687_HUMAN
NC score	0.015904 (rank : 397)	θ value	0.0330416 (rank : 171)
Query Neighborhood Hits	412	Target Neighborhood Hits	1244	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

NCOA1_HUMAN
NC score	0.015876 (rank : 398)	θ value	2.36792 (rank : 297)
Query Neighborhood Hits	412	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA2_HUMAN
NC score	0.015338 (rank : 399)	θ value	4.03905 (rank : 331)
Query Neighborhood Hits	412	Target Neighborhood Hits	281	Shared Neighborhood Hits	28
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

TREF1_MOUSE
NC score	0.014817 (rank : 400)	θ value	1.81305 (rank : 289)
Query Neighborhood Hits	412	Target Neighborhood Hits	682	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

NUP62_MOUSE
NC score	0.014717 (rank : 401)	θ value	8.99809 (rank : 407)
Query Neighborhood Hits	412	Target Neighborhood Hits	200	Shared Neighborhood Hits	10
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

JPH2_MOUSE
NC score	0.014644 (rank : 402)	θ value	8.99809 (rank : 403)
Query Neighborhood Hits	412	Target Neighborhood Hits	279	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CN004_HUMAN
NC score	0.014374 (rank : 403)	θ value	8.99809 (rank : 394)
Query Neighborhood Hits	412	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

TIF1G_MOUSE
NC score	0.014056 (rank : 404)	θ value	3.0926 (rank : 322)
Query Neighborhood Hits	412	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

NOL11_HUMAN
NC score	0.013960 (rank : 405)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	412	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8H0, Q7L5S1, Q9UG18	Gene names	NOL11
Domain Architecture	No domain graphic available
Description	Nucleolar protein 11.

HXA3_HUMAN
NC score	0.013536 (rank : 406)	θ value	0.62314 (rank : 232)
Query Neighborhood Hits	412	Target Neighborhood Hits	535	Shared Neighborhood Hits	49
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

HUWE1_MOUSE
NC score	0.013532 (rank : 407)	θ value	3.0926 (rank : 310)
Query Neighborhood Hits	412	Target Neighborhood Hits	406	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

GIT1_HUMAN
NC score	0.013321 (rank : 408)	θ value	3.0926 (rank : 308)
Query Neighborhood Hits	412	Target Neighborhood Hits	336	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

HXA3_MOUSE
NC score	0.013270 (rank : 409)	θ value	3.0926 (rank : 311)
Query Neighborhood Hits	412	Target Neighborhood Hits	558	Shared Neighborhood Hits	54
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

SH2D3_HUMAN
NC score	0.012965 (rank : 410)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	412	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

THSD1_MOUSE
NC score	0.012595 (rank : 411)	θ value	4.03905 (rank : 342)
Query Neighborhood Hits	412	Target Neighborhood Hits	153	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

GIT1_MOUSE
NC score	0.012505 (rank : 412)	θ value	3.0926 (rank : 309)
Query Neighborhood Hits	412	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

SH2D3_MOUSE
NC score	0.012401 (rank : 413)	θ value	2.36792 (rank : 299)
Query Neighborhood Hits	412	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

FA44A_HUMAN
NC score	0.012233 (rank : 414)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	412	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

CCD96_MOUSE
NC score	0.011996 (rank : 415)	θ value	1.81305 (rank : 281)
Query Neighborhood Hits	412	Target Neighborhood Hits	704	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

SORC1_HUMAN
NC score	0.011978 (rank : 416)	θ value	0.62314 (rank : 239)
Query Neighborhood Hits	412	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WY21, Q59GG7, Q5JVT7, Q5JVT8, Q5VY14, Q86WQ1, Q86WQ2, Q9H1Y1, Q9H1Y2	Gene names	SORCS1, SORCS
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (hSorCS).

TFE2_MOUSE
NC score	0.011916 (rank : 417)	θ value	3.0926 (rank : 320)
Query Neighborhood Hits	412	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

AP3B1_MOUSE
NC score	0.011889 (rank : 418)	θ value	5.27518 (rank : 347)
Query Neighborhood Hits	412	Target Neighborhood Hits	302	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

KCNH6_HUMAN
NC score	0.011783 (rank : 419)	θ value	0.813845 (rank : 249)
Query Neighborhood Hits	412	Target Neighborhood Hits	222	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

FOXP4_MOUSE
NC score	0.011720 (rank : 420)	θ value	8.99809 (rank : 401)
Query Neighborhood Hits	412	Target Neighborhood Hits	211	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

PSIP1_HUMAN
NC score	0.010596 (rank : 421)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	412	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

FAF1_HUMAN
NC score	0.010117 (rank : 422)	θ value	8.99809 (rank : 397)
Query Neighborhood Hits	412	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

FAF1_MOUSE
NC score	0.010090 (rank : 423)	θ value	8.99809 (rank : 398)
Query Neighborhood Hits	412	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

EXO1_MOUSE
NC score	0.009973 (rank : 424)	θ value	6.88961 (rank : 375)
Query Neighborhood Hits	412	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

LPPRC_HUMAN
NC score	0.009858 (rank : 425)	θ value	8.99809 (rank : 404)
Query Neighborhood Hits	412	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	P42704	Gene names	LRPPRC, LRP130
Domain Architecture	No domain graphic available
Description	130 kDa leucine-rich protein (LRP 130) (GP130) (Leucine-rich PPR motif-containing protein).

MYO9B_HUMAN
NC score	0.009825 (rank : 426)	θ value	0.813845 (rank : 250)
Query Neighborhood Hits	412	Target Neighborhood Hits	641	Shared Neighborhood Hits	58
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

HEN1_MOUSE
NC score	0.009784 (rank : 427)	θ value	2.36792 (rank : 294)
Query Neighborhood Hits	412	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HTF4_HUMAN
NC score	0.009545 (rank : 428)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	412	Target Neighborhood Hits	152	Shared Neighborhood Hits	14
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

NOG2_MOUSE
NC score	0.009458 (rank : 429)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	412	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.

FOXK2_HUMAN
NC score	0.008003 (rank : 430)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	412	Target Neighborhood Hits	190	Shared Neighborhood Hits	20
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

TLE1_MOUSE
NC score	0.007946 (rank : 431)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	412	Target Neighborhood Hits	491	Shared Neighborhood Hits	38
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

MOCOS_MOUSE
NC score	0.007261 (rank : 432)	θ value	8.99809 (rank : 405)
Query Neighborhood Hits	412	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q14CH1	Gene names	Mocos
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS).

MBD1_HUMAN
NC score	0.007231 (rank : 433)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	412	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

PAK4_MOUSE
NC score	0.007154 (rank : 434)	θ value	0.0563607 (rank : 183)
Query Neighborhood Hits	412	Target Neighborhood Hits	1098	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

ATF7_HUMAN
NC score	0.006669 (rank : 435)	θ value	8.99809 (rank : 393)
Query Neighborhood Hits	412	Target Neighborhood Hits	333	Shared Neighborhood Hits	13
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

EPS8_HUMAN
NC score	0.006512 (rank : 436)	θ value	5.27518 (rank : 354)
Query Neighborhood Hits	412	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

FOXGB_MOUSE
NC score	0.006454 (rank : 437)	θ value	8.99809 (rank : 400)
Query Neighborhood Hits	412	Target Neighborhood Hits	148	Shared Neighborhood Hits	23
SwissProt Accessions	Q60987, Q80VP3	Gene names	Foxg1b, Fkhl1, Foxg1, Hfhbf1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1).

TM55A_MOUSE
NC score	0.005913 (rank : 438)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	412	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZX7	Gene names	Tmem55a
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55A (EC 3.1.3.-) (Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase II).

NFAC1_MOUSE
NC score	0.005854 (rank : 439)	θ value	6.88961 (rank : 384)
Query Neighborhood Hits	412	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SOX10_HUMAN
NC score	0.005799 (rank : 440)	θ value	1.81305 (rank : 287)
Query Neighborhood Hits	412	Target Neighborhood Hits	122	Shared Neighborhood Hits	12
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

HXD4_MOUSE
NC score	0.005544 (rank : 441)	θ value	1.06291 (rank : 260)
Query Neighborhood Hits	412	Target Neighborhood Hits	339	Shared Neighborhood Hits	18
SwissProt Accessions	P10628, P97451, Q3UXL6	Gene names	Hoxd4, Hox-4.2, Hoxd-4
Domain Architecture
Description	Homeobox protein Hox-D4 (Hox-4.2) (Hox-5.1).

CAC1B_MOUSE
NC score	0.005450 (rank : 442)	θ value	5.27518 (rank : 349)
Query Neighborhood Hits	412	Target Neighborhood Hits	351	Shared Neighborhood Hits	27
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

STIM1_HUMAN
NC score	0.005381 (rank : 443)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	412	Target Neighborhood Hits	665	Shared Neighborhood Hits	22
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

CROCC_HUMAN
NC score	0.005311 (rank : 444)	θ value	4.03905 (rank : 327)
Query Neighborhood Hits	412	Target Neighborhood Hits	1409	Shared Neighborhood Hits	49
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

NPAS3_HUMAN
NC score	0.005038 (rank : 445)	θ value	8.99809 (rank : 406)
Query Neighborhood Hits	412	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

TEAD2_HUMAN
NC score	0.004994 (rank : 446)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	412	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q15562, Q96IG3	Gene names	TEAD2, TEF4
Domain Architecture
Description	Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2).

CD2L7_HUMAN
NC score	0.004662 (rank : 447)	θ value	6.88961 (rank : 372)
Query Neighborhood Hits	412	Target Neighborhood Hits	1275	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

PKP4_HUMAN
NC score	0.004411 (rank : 448)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	412	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

FX4L1_HUMAN
NC score	0.003743 (rank : 449)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	412	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NU39	Gene names	FOXD4L1
Domain Architecture
Description	Forkhead box protein D4-like 1.

NFM_MOUSE
NC score	0.003435 (rank : 450)	θ value	3.0926 (rank : 316)
Query Neighborhood Hits	412	Target Neighborhood Hits	1159	Shared Neighborhood Hits	45
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

MMP15_HUMAN
NC score	0.003347 (rank : 451)	θ value	3.0926 (rank : 314)
Query Neighborhood Hits	412	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MEOX1_HUMAN
NC score	0.002896 (rank : 452)	θ value	1.38821 (rank : 271)
Query Neighborhood Hits	412	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	P50221	Gene names	MEOX1, MOX1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

FOG1_HUMAN
NC score	0.001784 (rank : 453)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	412	Target Neighborhood Hits	981	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

ACRO_HUMAN
NC score	0.001631 (rank : 454)	θ value	1.38821 (rank : 267)
Query Neighborhood Hits	412	Target Neighborhood Hits	291	Shared Neighborhood Hits	26
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

SIGL5_HUMAN
NC score	0.001551 (rank : 455)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	412	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

DLX5_MOUSE
NC score	0.001053 (rank : 456)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	412	Target Neighborhood Hits	434	Shared Neighborhood Hits	21
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

KCC2B_HUMAN
NC score	0.000346 (rank : 457)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	412	Target Neighborhood Hits	866	Shared Neighborhood Hits	23
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

HXD13_HUMAN
NC score	-0.000149 (rank : 458)	θ value	8.99809 (rank : 402)
Query Neighborhood Hits	412	Target Neighborhood Hits	332	Shared Neighborhood Hits	12
SwissProt Accessions	P35453	Gene names	HOXD13, HOX4I
Domain Architecture
Description	Homeobox protein Hox-D13 (Hox-4I).

M3K5_HUMAN
NC score	-0.000156 (rank : 459)	θ value	3.0926 (rank : 313)
Query Neighborhood Hits	412	Target Neighborhood Hits	868	Shared Neighborhood Hits	15
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

ABCA4_MOUSE
NC score	-0.000661 (rank : 460)	θ value	8.99809 (rank : 392)
Query Neighborhood Hits	412	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

CDK8_HUMAN
NC score	-0.000919 (rank : 461)	θ value	3.0926 (rank : 303)
Query Neighborhood Hits	412	Target Neighborhood Hits	831	Shared Neighborhood Hits	14
SwissProt Accessions	P49336	Gene names	CDK8
Domain Architecture
Description	Cell division protein kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Protein kinase K35).

ZBT45_HUMAN
NC score	-0.006665 (rank : 462)	θ value	3.0926 (rank : 323)
Query Neighborhood Hits	412	Target Neighborhood Hits	901	Shared Neighborhood Hits	32
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

ZN142_HUMAN
NC score	-0.007446 (rank : 463)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	412	Target Neighborhood Hits	1007	Shared Neighborhood Hits	55
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ZBTB5_MOUSE
NC score	-0.008423 (rank : 464)	θ value	3.0926 (rank : 324)
Query Neighborhood Hits	412	Target Neighborhood Hits	801	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).