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Network neighborhood for query Sequence : PTN3_HUMAN

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PTN3_HUMAN
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTN3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	258	Target Neighborhood Hits	258	Shared Neighborhood Hits	258
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	0 (rank : 2)	NC score	0.990853 (rank : 2)
Query Neighborhood Hits	258	Target Neighborhood Hits	303	Shared Neighborhood Hits	216
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

E41L1_MOUSE
θ value	8.55514e-59 (rank : 3)	NC score	0.648053 (rank : 66)
Query Neighborhood Hits	258	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_HUMAN
θ value	1.11734e-58 (rank : 4)	NC score	0.647611 (rank : 67)
Query Neighborhood Hits	258	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L2_HUMAN
θ value	1.11734e-58 (rank : 5)	NC score	0.638599 (rank : 71)
Query Neighborhood Hits	258	Target Neighborhood Hits	287	Shared Neighborhood Hits	53
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L1_HUMAN
θ value	1.45929e-58 (rank : 6)	NC score	0.644706 (rank : 69)
Query Neighborhood Hits	258	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_HUMAN
θ value	4.24587e-58 (rank : 7)	NC score	0.649843 (rank : 64)
Query Neighborhood Hits	258	Target Neighborhood Hits	113	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L3_MOUSE
θ value	1.23536e-57 (rank : 8)	NC score	0.639702 (rank : 70)
Query Neighborhood Hits	258	Target Neighborhood Hits	250	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_MOUSE
θ value	3.59435e-57 (rank : 9)	NC score	0.621484 (rank : 72)
Query Neighborhood Hits	258	Target Neighborhood Hits	459	Shared Neighborhood Hits	52
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

41_MOUSE
θ value	1.78386e-56 (rank : 10)	NC score	0.645444 (rank : 68)
Query Neighborhood Hits	258	Target Neighborhood Hits	184	Shared Neighborhood Hits	50
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

PTN14_HUMAN
θ value	1.51013e-55 (rank : 11)	NC score	0.926253 (rank : 6)
Query Neighborhood Hits	258	Target Neighborhood Hits	163	Shared Neighborhood Hits	113
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	3.1488e-53 (rank : 12)	NC score	0.927464 (rank : 5)
Query Neighborhood Hits	258	Target Neighborhood Hits	142	Shared Neighborhood Hits	112
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

E41L5_HUMAN
θ value	5.37103e-53 (rank : 13)	NC score	0.653987 (rank : 58)
Query Neighborhood Hits	258	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
θ value	1.46268e-50 (rank : 14)	NC score	0.653845 (rank : 59)
Query Neighborhood Hits	258	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FARP1_HUMAN
θ value	9.48078e-50 (rank : 15)	NC score	0.540021 (rank : 82)
Query Neighborhood Hits	258	Target Neighborhood Hits	241	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PTN21_HUMAN
θ value	1.61718e-49 (rank : 16)	NC score	0.930099 (rank : 3)
Query Neighborhood Hits	258	Target Neighborhood Hits	143	Shared Neighborhood Hits	103
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	1.61718e-49 (rank : 17)	NC score	0.930007 (rank : 4)
Query Neighborhood Hits	258	Target Neighborhood Hits	155	Shared Neighborhood Hits	102
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

E41LA_HUMAN
θ value	2.1121e-49 (rank : 18)	NC score	0.653753 (rank : 60)
Query Neighborhood Hits	258	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_HUMAN
θ value	2.1121e-49 (rank : 19)	NC score	0.649005 (rank : 65)
Query Neighborhood Hits	258	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

PTN13_MOUSE
θ value	2.1121e-49 (rank : 20)	NC score	0.875964 (rank : 7)
Query Neighborhood Hits	258	Target Neighborhood Hits	426	Shared Neighborhood Hits	219
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN2_HUMAN
θ value	3.04986e-48 (rank : 21)	NC score	0.770347 (rank : 12)
Query Neighborhood Hits	258	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	3.04986e-48 (rank : 22)	NC score	0.770539 (rank : 11)
Query Neighborhood Hits	258	Target Neighborhood Hits	107	Shared Neighborhood Hits	67
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

E41LA_MOUSE
θ value	3.98324e-48 (rank : 23)	NC score	0.653731 (rank : 61)
Query Neighborhood Hits	258	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP2_MOUSE
θ value	3.98324e-48 (rank : 24)	NC score	0.519509 (rank : 88)
Query Neighborhood Hits	258	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN13_HUMAN
θ value	5.20228e-48 (rank : 25)	NC score	0.867212 (rank : 8)
Query Neighborhood Hits	258	Target Neighborhood Hits	471	Shared Neighborhood Hits	218
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN1_MOUSE
θ value	6.35935e-46 (rank : 26)	NC score	0.771220 (rank : 9)
Query Neighborhood Hits	258	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTPRJ_HUMAN
θ value	1.41672e-45 (rank : 27)	NC score	0.730323 (rank : 39)
Query Neighborhood Hits	258	Target Neighborhood Hits	207	Shared Neighborhood Hits	78
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

FARP2_HUMAN
θ value	3.15612e-45 (rank : 28)	NC score	0.524154 (rank : 86)
Query Neighborhood Hits	258	Target Neighborhood Hits	240	Shared Neighborhood Hits	52
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN1_HUMAN
θ value	4.122e-45 (rank : 29)	NC score	0.770928 (rank : 10)
Query Neighborhood Hits	258	Target Neighborhood Hits	84	Shared Neighborhood Hits	72
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTPRJ_MOUSE
θ value	1.19932e-44 (rank : 30)	NC score	0.733629 (rank : 38)
Query Neighborhood Hits	258	Target Neighborhood Hits	188	Shared Neighborhood Hits	74
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

FRMD5_HUMAN
θ value	2.04573e-44 (rank : 31)	NC score	0.649968 (rank : 63)
Query Neighborhood Hits	258	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

PTPRB_HUMAN
θ value	4.55743e-44 (rank : 32)	NC score	0.703946 (rank : 43)
Query Neighborhood Hits	258	Target Neighborhood Hits	242	Shared Neighborhood Hits	75
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

FRMD5_MOUSE
θ value	7.77379e-44 (rank : 33)	NC score	0.651355 (rank : 62)
Query Neighborhood Hits	258	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

PTPRS_HUMAN
θ value	6.58091e-43 (rank : 34)	NC score	0.545062 (rank : 81)
Query Neighborhood Hits	258	Target Neighborhood Hits	472	Shared Neighborhood Hits	76
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRK_MOUSE
θ value	3.26607e-42 (rank : 35)	NC score	0.697407 (rank : 47)
Query Neighborhood Hits	258	Target Neighborhood Hits	223	Shared Neighborhood Hits	67
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN18_HUMAN
θ value	5.57106e-42 (rank : 36)	NC score	0.768011 (rank : 13)
Query Neighborhood Hits	258	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTPRD_HUMAN
θ value	5.57106e-42 (rank : 37)	NC score	0.534820 (rank : 83)
Query Neighborhood Hits	258	Target Neighborhood Hits	485	Shared Neighborhood Hits	78
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRK_HUMAN
θ value	5.57106e-42 (rank : 38)	NC score	0.699081 (rank : 46)
Query Neighborhood Hits	258	Target Neighborhood Hits	228	Shared Neighborhood Hits	67
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRO_HUMAN
θ value	5.57106e-42 (rank : 39)	NC score	0.754336 (rank : 20)
Query Neighborhood Hits	258	Target Neighborhood Hits	139	Shared Neighborhood Hits	73
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTN6_MOUSE
θ value	2.11701e-41 (rank : 40)	NC score	0.718515 (rank : 42)
Query Neighborhood Hits	258	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRE_HUMAN
θ value	2.11701e-41 (rank : 41)	NC score	0.747485 (rank : 31)
Query Neighborhood Hits	258	Target Neighborhood Hits	92	Shared Neighborhood Hits	70
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTN18_MOUSE
θ value	2.76489e-41 (rank : 42)	NC score	0.766138 (rank : 14)
Query Neighborhood Hits	258	Target Neighborhood Hits	134	Shared Neighborhood Hits	72
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
θ value	2.76489e-41 (rank : 43)	NC score	0.752345 (rank : 23)
Query Neighborhood Hits	258	Target Neighborhood Hits	79	Shared Neighborhood Hits	64
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_HUMAN
θ value	4.71619e-41 (rank : 44)	NC score	0.758942 (rank : 17)
Query Neighborhood Hits	258	Target Neighborhood Hits	109	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN9_MOUSE
θ value	6.15952e-41 (rank : 45)	NC score	0.752538 (rank : 21)
Query Neighborhood Hits	258	Target Neighborhood Hits	78	Shared Neighborhood Hits	64
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN6_HUMAN
θ value	8.04462e-41 (rank : 46)	NC score	0.720711 (rank : 41)
Query Neighborhood Hits	258	Target Neighborhood Hits	234	Shared Neighborhood Hits	72
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTPRF_HUMAN
θ value	8.04462e-41 (rank : 47)	NC score	0.531990 (rank : 84)
Query Neighborhood Hits	258	Target Neighborhood Hits	489	Shared Neighborhood Hits	76
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_MOUSE
θ value	8.04462e-41 (rank : 48)	NC score	0.672437 (rank : 55)
Query Neighborhood Hits	258	Target Neighborhood Hits	260	Shared Neighborhood Hits	68
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRT_HUMAN
θ value	2.34062e-40 (rank : 49)	NC score	0.693842 (rank : 48)
Query Neighborhood Hits	258	Target Neighborhood Hits	217	Shared Neighborhood Hits	67
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	2.34062e-40 (rank : 50)	NC score	0.693841 (rank : 49)
Query Neighborhood Hits	258	Target Neighborhood Hits	219	Shared Neighborhood Hits	67
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRA_HUMAN
θ value	3.99248e-40 (rank : 51)	NC score	0.746987 (rank : 32)
Query Neighborhood Hits	258	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	3.99248e-40 (rank : 52)	NC score	0.746515 (rank : 34)
Query Neighborhood Hits	258	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRM_HUMAN
θ value	5.21438e-40 (rank : 53)	NC score	0.681449 (rank : 52)
Query Neighborhood Hits	258	Target Neighborhood Hits	244	Shared Neighborhood Hits	68
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRV_MOUSE
θ value	5.21438e-40 (rank : 54)	NC score	0.723723 (rank : 40)
Query Neighborhood Hits	258	Target Neighborhood Hits	179	Shared Neighborhood Hits	69
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN11_MOUSE
θ value	6.81017e-40 (rank : 55)	NC score	0.700935 (rank : 44)
Query Neighborhood Hits	258	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTPRM_MOUSE
θ value	6.81017e-40 (rank : 56)	NC score	0.683051 (rank : 51)
Query Neighborhood Hits	258	Target Neighborhood Hits	238	Shared Neighborhood Hits	68
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRG_HUMAN
θ value	8.89434e-40 (rank : 57)	NC score	0.674474 (rank : 53)
Query Neighborhood Hits	258	Target Neighborhood Hits	231	Shared Neighborhood Hits	63
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTN11_HUMAN
θ value	1.51715e-39 (rank : 58)	NC score	0.700870 (rank : 45)
Query Neighborhood Hits	258	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTPRE_MOUSE
θ value	4.41421e-39 (rank : 59)	NC score	0.746816 (rank : 33)
Query Neighborhood Hits	258	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

CD45_HUMAN
θ value	9.83387e-39 (rank : 60)	NC score	0.743017 (rank : 36)
Query Neighborhood Hits	258	Target Neighborhood Hits	243	Shared Neighborhood Hits	68
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPR2_MOUSE
θ value	2.19075e-38 (rank : 61)	NC score	0.749898 (rank : 27)
Query Neighborhood Hits	258	Target Neighborhood Hits	120	Shared Neighborhood Hits	68
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

CD45_MOUSE
θ value	2.86122e-38 (rank : 62)	NC score	0.748587 (rank : 28)
Query Neighborhood Hits	258	Target Neighborhood Hits	178	Shared Neighborhood Hits	68
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRD_MOUSE
θ value	4.88048e-38 (rank : 63)	NC score	0.525503 (rank : 85)
Query Neighborhood Hits	258	Target Neighborhood Hits	491	Shared Neighborhood Hits	78
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTN22_MOUSE
θ value	8.32485e-38 (rank : 64)	NC score	0.752413 (rank : 22)
Query Neighborhood Hits	258	Target Neighborhood Hits	179	Shared Neighborhood Hits	68
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPR2_HUMAN
θ value	1.20211e-36 (rank : 65)	NC score	0.751375 (rank : 25)
Query Neighborhood Hits	258	Target Neighborhood Hits	103	Shared Neighborhood Hits	68
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTN12_HUMAN
θ value	2.67802e-36 (rank : 66)	NC score	0.757231 (rank : 18)
Query Neighborhood Hits	258	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN7_MOUSE
θ value	4.568e-36 (rank : 67)	NC score	0.761755 (rank : 15)
Query Neighborhood Hits	258	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN12_MOUSE
θ value	7.79185e-36 (rank : 68)	NC score	0.756713 (rank : 19)
Query Neighborhood Hits	258	Target Neighborhood Hits	123	Shared Neighborhood Hits	67
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRZ_HUMAN
θ value	1.01765e-35 (rank : 69)	NC score	0.674341 (rank : 54)
Query Neighborhood Hits	258	Target Neighborhood Hits	255	Shared Neighborhood Hits	66
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRN_HUMAN
θ value	1.32909e-35 (rank : 70)	NC score	0.745686 (rank : 35)
Query Neighborhood Hits	258	Target Neighborhood Hits	156	Shared Neighborhood Hits	67
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	2.26708e-35 (rank : 71)	NC score	0.742314 (rank : 37)
Query Neighborhood Hits	258	Target Neighborhood Hits	240	Shared Neighborhood Hits	68
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTN23_HUMAN
θ value	8.61488e-35 (rank : 72)	NC score	0.660635 (rank : 56)
Query Neighborhood Hits	258	Target Neighborhood Hits	646	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN7_HUMAN
θ value	1.12514e-34 (rank : 73)	NC score	0.760818 (rank : 16)
Query Neighborhood Hits	258	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

RADI_HUMAN
θ value	1.12514e-34 (rank : 74)	NC score	0.507562 (rank : 90)
Query Neighborhood Hits	258	Target Neighborhood Hits	741	Shared Neighborhood Hits	53
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	1.12514e-34 (rank : 75)	NC score	0.504762 (rank : 91)
Query Neighborhood Hits	258	Target Neighborhood Hits	773	Shared Neighborhood Hits	52
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

PTPRU_HUMAN
θ value	1.46948e-34 (rank : 76)	NC score	0.686403 (rank : 50)
Query Neighborhood Hits	258	Target Neighborhood Hits	237	Shared Neighborhood Hits	70
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTN23_MOUSE
θ value	2.50655e-34 (rank : 77)	NC score	0.660083 (rank : 57)
Query Neighborhood Hits	258	Target Neighborhood Hits	726	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

EZRI_MOUSE
θ value	6.17384e-33 (rank : 78)	NC score	0.516305 (rank : 89)
Query Neighborhood Hits	258	Target Neighborhood Hits	693	Shared Neighborhood Hits	52
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_HUMAN
θ value	8.06329e-33 (rank : 79)	NC score	0.519687 (rank : 87)
Query Neighborhood Hits	258	Target Neighborhood Hits	663	Shared Neighborhood Hits	53
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MOES_MOUSE
θ value	4.00176e-32 (rank : 80)	NC score	0.470113 (rank : 96)
Query Neighborhood Hits	258	Target Neighborhood Hits	923	Shared Neighborhood Hits	55
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	8.91499e-32 (rank : 81)	NC score	0.475113 (rank : 95)
Query Neighborhood Hits	258	Target Neighborhood Hits	892	Shared Neighborhood Hits	53
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MERL_HUMAN
θ value	1.52067e-31 (rank : 82)	NC score	0.547370 (rank : 78)
Query Neighborhood Hits	258	Target Neighborhood Hits	532	Shared Neighborhood Hits	54
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	1.98606e-31 (rank : 83)	NC score	0.547931 (rank : 77)
Query Neighborhood Hits	258	Target Neighborhood Hits	524	Shared Neighborhood Hits	54
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTPRR_HUMAN
θ value	3.3877e-31 (rank : 84)	NC score	0.747854 (rank : 29)
Query Neighborhood Hits	258	Target Neighborhood Hits	77	Shared Neighborhood Hits	66
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTN5_MOUSE
θ value	5.77852e-31 (rank : 85)	NC score	0.751647 (rank : 24)
Query Neighborhood Hits	258	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRR_MOUSE
θ value	7.54701e-31 (rank : 86)	NC score	0.747496 (rank : 30)
Query Neighborhood Hits	258	Target Neighborhood Hits	84	Shared Neighborhood Hits	69
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

MYLIP_MOUSE
θ value	3.74554e-30 (rank : 87)	NC score	0.599208 (rank : 73)
Query Neighborhood Hits	258	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
θ value	1.4233e-29 (rank : 88)	NC score	0.587294 (rank : 74)
Query Neighborhood Hits	258	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PTN5_HUMAN
θ value	1.02001e-27 (rank : 89)	NC score	0.750426 (rank : 26)
Query Neighborhood Hits	258	Target Neighborhood Hits	80	Shared Neighborhood Hits	68
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

FRM4B_MOUSE
θ value	1.5773e-20 (rank : 90)	NC score	0.553843 (rank : 76)
Query Neighborhood Hits	258	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4B_HUMAN
θ value	2.69047e-20 (rank : 91)	NC score	0.555067 (rank : 75)
Query Neighborhood Hits	258	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4A_MOUSE
θ value	3.63628e-17 (rank : 92)	NC score	0.546804 (rank : 80)
Query Neighborhood Hits	258	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
θ value	4.74913e-17 (rank : 93)	NC score	0.547302 (rank : 79)
Query Neighborhood Hits	258	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRMD6_MOUSE
θ value	2.69671e-12 (rank : 94)	NC score	0.494706 (rank : 92)
Query Neighborhood Hits	258	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
θ value	6.00763e-12 (rank : 95)	NC score	0.489021 (rank : 93)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD1_HUMAN
θ value	1.63604e-09 (rank : 96)	NC score	0.481699 (rank : 94)
Query Neighborhood Hits	258	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

TLN1_HUMAN
θ value	8.11959e-09 (rank : 97)	NC score	0.301779 (rank : 97)
Query Neighborhood Hits	258	Target Neighborhood Hits	218	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	8.11959e-09 (rank : 98)	NC score	0.299491 (rank : 98)
Query Neighborhood Hits	258	Target Neighborhood Hits	213	Shared Neighborhood Hits	47
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
θ value	2.36244e-08 (rank : 99)	NC score	0.294508 (rank : 100)
Query Neighborhood Hits	258	Target Neighborhood Hits	157	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	3.08544e-08 (rank : 100)	NC score	0.297967 (rank : 99)
Query Neighborhood Hits	258	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

SNTB2_HUMAN
θ value	1.17247e-07 (rank : 101)	NC score	0.205613 (rank : 111)
Query Neighborhood Hits	258	Target Neighborhood Hits	180	Shared Neighborhood Hits	113
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	1.17247e-07 (rank : 102)	NC score	0.205480 (rank : 112)
Query Neighborhood Hits	258	Target Neighborhood Hits	181	Shared Neighborhood Hits	113
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB1_HUMAN
θ value	3.77169e-06 (rank : 103)	NC score	0.194792 (rank : 115)
Query Neighborhood Hits	258	Target Neighborhood Hits	157	Shared Neighborhood Hits	106
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	3.77169e-06 (rank : 104)	NC score	0.194551 (rank : 116)
Query Neighborhood Hits	258	Target Neighborhood Hits	160	Shared Neighborhood Hits	106
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

LIN7A_HUMAN
θ value	6.43352e-06 (rank : 105)	NC score	0.206445 (rank : 108)
Query Neighborhood Hits	258	Target Neighborhood Hits	193	Shared Neighborhood Hits	116
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	6.43352e-06 (rank : 106)	NC score	0.206379 (rank : 109)
Query Neighborhood Hits	258	Target Neighborhood Hits	193	Shared Neighborhood Hits	116
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7B_HUMAN
θ value	6.43352e-06 (rank : 107)	NC score	0.206446 (rank : 107)
Query Neighborhood Hits	258	Target Neighborhood Hits	200	Shared Neighborhood Hits	116
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

SYP2L_HUMAN
θ value	6.43352e-06 (rank : 108)	NC score	0.153198 (rank : 143)
Query Neighborhood Hits	258	Target Neighborhood Hits	400	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

LIN7B_MOUSE
θ value	8.40245e-06 (rank : 109)	NC score	0.206116 (rank : 110)
Query Neighborhood Hits	258	Target Neighborhood Hits	200	Shared Neighborhood Hits	116
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

SNTA1_HUMAN
θ value	8.40245e-06 (rank : 110)	NC score	0.195299 (rank : 113)
Query Neighborhood Hits	258	Target Neighborhood Hits	186	Shared Neighborhood Hits	109
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

LIN7C_HUMAN
θ value	1.09739e-05 (rank : 111)	NC score	0.208431 (rank : 105)
Query Neighborhood Hits	258	Target Neighborhood Hits	198	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	1.09739e-05 (rank : 112)	NC score	0.208431 (rank : 106)
Query Neighborhood Hits	258	Target Neighborhood Hits	198	Shared Neighborhood Hits	116
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

SNTA1_MOUSE
θ value	1.09739e-05 (rank : 113)	NC score	0.195282 (rank : 114)
Query Neighborhood Hits	258	Target Neighborhood Hits	170	Shared Neighborhood Hits	108
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PDZ11_MOUSE
θ value	1.43324e-05 (rank : 114)	NC score	0.218443 (rank : 103)
Query Neighborhood Hits	258	Target Neighborhood Hits	154	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SYP2L_MOUSE
θ value	2.44474e-05 (rank : 115)	NC score	0.133203 (rank : 169)
Query Neighborhood Hits	258	Target Neighborhood Hits	289	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

MAGI2_HUMAN
θ value	3.19293e-05 (rank : 116)	NC score	0.169241 (rank : 128)
Query Neighborhood Hits	258	Target Neighborhood Hits	373	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

LDB3_HUMAN
θ value	4.1701e-05 (rank : 117)	NC score	0.103761 (rank : 202)
Query Neighborhood Hits	258	Target Neighborhood Hits	497	Shared Neighborhood Hits	100
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	4.1701e-05 (rank : 118)	NC score	0.105526 (rank : 198)
Query Neighborhood Hits	258	Target Neighborhood Hits	510	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MAGI1_MOUSE
θ value	4.1701e-05 (rank : 119)	NC score	0.166075 (rank : 132)
Query Neighborhood Hits	258	Target Neighborhood Hits	403	Shared Neighborhood Hits	117
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

SYNP2_HUMAN
θ value	4.1701e-05 (rank : 120)	NC score	0.139638 (rank : 155)
Query Neighborhood Hits	258	Target Neighborhood Hits	323	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYNP2_MOUSE
θ value	4.1701e-05 (rank : 121)	NC score	0.151921 (rank : 145)
Query Neighborhood Hits	258	Target Neighborhood Hits	252	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

PDLI3_MOUSE
θ value	7.1131e-05 (rank : 122)	NC score	0.134970 (rank : 164)
Query Neighborhood Hits	258	Target Neighborhood Hits	197	Shared Neighborhood Hits	97
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDZ11_HUMAN
θ value	7.1131e-05 (rank : 123)	NC score	0.216663 (rank : 104)
Query Neighborhood Hits	258	Target Neighborhood Hits	160	Shared Neighborhood Hits	112
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

GOPC_HUMAN
θ value	9.29e-05 (rank : 124)	NC score	0.188035 (rank : 119)
Query Neighborhood Hits	258	Target Neighborhood Hits	377	Shared Neighborhood Hits	117
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	9.29e-05 (rank : 125)	NC score	0.189746 (rank : 117)
Query Neighborhood Hits	258	Target Neighborhood Hits	323	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

MAGI1_HUMAN
θ value	9.29e-05 (rank : 126)	NC score	0.165512 (rank : 133)
Query Neighborhood Hits	258	Target Neighborhood Hits	388	Shared Neighborhood Hits	116
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI2_MOUSE
θ value	9.29e-05 (rank : 127)	NC score	0.169037 (rank : 129)
Query Neighborhood Hits	258	Target Neighborhood Hits	370	Shared Neighborhood Hits	118
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

SNTG1_HUMAN
θ value	0.000121331 (rank : 128)	NC score	0.186156 (rank : 122)
Query Neighborhood Hits	258	Target Neighborhood Hits	181	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDLI1_MOUSE
θ value	0.000158464 (rank : 129)	NC score	0.136180 (rank : 162)
Query Neighborhood Hits	258	Target Neighborhood Hits	213	Shared Neighborhood Hits	86
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

SNTG1_MOUSE
θ value	0.000158464 (rank : 130)	NC score	0.186800 (rank : 120)
Query Neighborhood Hits	258	Target Neighborhood Hits	179	Shared Neighborhood Hits	113
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDLI3_HUMAN
θ value	0.000461057 (rank : 131)	NC score	0.137274 (rank : 161)
Query Neighborhood Hits	258	Target Neighborhood Hits	199	Shared Neighborhood Hits	101
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI1_HUMAN
θ value	0.000786445 (rank : 132)	NC score	0.130895 (rank : 173)
Query Neighborhood Hits	258	Target Neighborhood Hits	242	Shared Neighborhood Hits	88
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

WHRN_MOUSE
θ value	0.000786445 (rank : 133)	NC score	0.180378 (rank : 125)
Query Neighborhood Hits	258	Target Neighborhood Hits	412	Shared Neighborhood Hits	117
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

APXL_HUMAN
θ value	0.00102713 (rank : 134)	NC score	0.128338 (rank : 177)
Query Neighborhood Hits	258	Target Neighborhood Hits	553	Shared Neighborhood Hits	78
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

NHRF2_HUMAN
θ value	0.00102713 (rank : 135)	NC score	0.164766 (rank : 135)
Query Neighborhood Hits	258	Target Neighborhood Hits	197	Shared Neighborhood Hits	112
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
θ value	0.00102713 (rank : 136)	NC score	0.161938 (rank : 138)
Query Neighborhood Hits	258	Target Neighborhood Hits	194	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

SNTG2_MOUSE
θ value	0.00102713 (rank : 137)	NC score	0.186236 (rank : 121)
Query Neighborhood Hits	258	Target Neighborhood Hits	176	Shared Neighborhood Hits	112
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

WHRN_HUMAN
θ value	0.00102713 (rank : 138)	NC score	0.177841 (rank : 126)
Query Neighborhood Hits	258	Target Neighborhood Hits	325	Shared Neighborhood Hits	115
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

IL16_MOUSE
θ value	0.00175202 (rank : 139)	NC score	0.158294 (rank : 140)
Query Neighborhood Hits	258	Target Neighborhood Hits	189	Shared Neighborhood Hits	94
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTG2_HUMAN
θ value	0.00175202 (rank : 140)	NC score	0.184667 (rank : 124)
Query Neighborhood Hits	258	Target Neighborhood Hits	191	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

LAP2_HUMAN
θ value	0.00390308 (rank : 141)	NC score	0.058961 (rank : 291)
Query Neighborhood Hits	258	Target Neighborhood Hits	499	Shared Neighborhood Hits	87
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

IL16_HUMAN
θ value	0.00869519 (rank : 142)	NC score	0.158664 (rank : 139)
Query Neighborhood Hits	258	Target Neighborhood Hits	207	Shared Neighborhood Hits	95
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PZRN3_HUMAN
θ value	0.00869519 (rank : 143)	NC score	0.118612 (rank : 188)
Query Neighborhood Hits	258	Target Neighborhood Hits	461	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LAP2_MOUSE
θ value	0.0113563 (rank : 144)	NC score	0.056180 (rank : 308)
Query Neighborhood Hits	258	Target Neighborhood Hits	482	Shared Neighborhood Hits	86
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP4_MOUSE
θ value	0.0148317 (rank : 145)	NC score	0.105176 (rank : 199)
Query Neighborhood Hits	258	Target Neighborhood Hits	590	Shared Neighborhood Hits	118
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PZRN3_MOUSE
θ value	0.0148317 (rank : 146)	NC score	0.117715 (rank : 190)
Query Neighborhood Hits	258	Target Neighborhood Hits	447	Shared Neighborhood Hits	95
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SYJ2B_HUMAN
θ value	0.0148317 (rank : 147)	NC score	0.185001 (rank : 123)
Query Neighborhood Hits	258	Target Neighborhood Hits	162	Shared Neighborhood Hits	108
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

DLG4_HUMAN
θ value	0.0193708 (rank : 148)	NC score	0.137365 (rank : 160)
Query Neighborhood Hits	258	Target Neighborhood Hits	286	Shared Neighborhood Hits	111
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	0.0193708 (rank : 149)	NC score	0.137529 (rank : 157)
Query Neighborhood Hits	258	Target Neighborhood Hits	282	Shared Neighborhood Hits	111
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DUS5_HUMAN
θ value	0.0193708 (rank : 150)	NC score	0.048744 (rank : 331)
Query Neighborhood Hits	258	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

NHERF_HUMAN
θ value	0.0193708 (rank : 151)	NC score	0.164144 (rank : 136)
Query Neighborhood Hits	258	Target Neighborhood Hits	190	Shared Neighborhood Hits	115
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

USH1C_HUMAN
θ value	0.0193708 (rank : 152)	NC score	0.171737 (rank : 127)
Query Neighborhood Hits	258	Target Neighborhood Hits	327	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.0193708 (rank : 153)	NC score	0.163024 (rank : 137)
Query Neighborhood Hits	258	Target Neighborhood Hits	557	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PDZD1_MOUSE
θ value	0.0252991 (rank : 154)	NC score	0.157901 (rank : 141)
Query Neighborhood Hits	258	Target Neighborhood Hits	191	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD3_MOUSE
θ value	0.0252991 (rank : 155)	NC score	0.134934 (rank : 165)
Query Neighborhood Hits	258	Target Neighborhood Hits	171	Shared Neighborhood Hits	109
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PDZD7_HUMAN
θ value	0.0252991 (rank : 156)	NC score	0.189400 (rank : 118)
Query Neighborhood Hits	258	Target Neighborhood Hits	181	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

DLG2_HUMAN
θ value	0.0330416 (rank : 157)	NC score	0.132628 (rank : 171)
Query Neighborhood Hits	258	Target Neighborhood Hits	279	Shared Neighborhood Hits	108
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	0.0330416 (rank : 158)	NC score	0.133201 (rank : 170)
Query Neighborhood Hits	258	Target Neighborhood Hits	271	Shared Neighborhood Hits	107
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

NHERF_MOUSE
θ value	0.0330416 (rank : 159)	NC score	0.165266 (rank : 134)
Query Neighborhood Hits	258	Target Neighborhood Hits	195	Shared Neighborhood Hits	115
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

DLG3_HUMAN
θ value	0.0431538 (rank : 160)	NC score	0.133428 (rank : 168)
Query Neighborhood Hits	258	Target Neighborhood Hits	269	Shared Neighborhood Hits	110
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	0.0431538 (rank : 161)	NC score	0.133492 (rank : 167)
Query Neighborhood Hits	258	Target Neighborhood Hits	274	Shared Neighborhood Hits	110
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

PDLI4_HUMAN
θ value	0.0431538 (rank : 162)	NC score	0.123432 (rank : 183)
Query Neighborhood Hits	258	Target Neighborhood Hits	245	Shared Neighborhood Hits	96
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

ZO2_HUMAN
θ value	0.0431538 (rank : 163)	NC score	0.121942 (rank : 185)
Query Neighborhood Hits	258	Target Neighborhood Hits	289	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DUS4_HUMAN
θ value	0.0563607 (rank : 164)	NC score	0.043298 (rank : 333)
Query Neighborhood Hits	258	Target Neighborhood Hits	77	Shared Neighborhood Hits	31
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS4_MOUSE
θ value	0.0563607 (rank : 165)	NC score	0.043463 (rank : 332)
Query Neighborhood Hits	258	Target Neighborhood Hits	75	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS23_MOUSE
θ value	0.0961366 (rank : 166)	NC score	0.245656 (rank : 101)
Query Neighborhood Hits	258	Target Neighborhood Hits	94	Shared Neighborhood Hits	66
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

LRRC7_HUMAN
θ value	0.0961366 (rank : 167)	NC score	0.063514 (rank : 269)
Query Neighborhood Hits	258	Target Neighborhood Hits	423	Shared Neighborhood Hits	96
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.0961366 (rank : 168)	NC score	0.062974 (rank : 270)
Query Neighborhood Hits	258	Target Neighborhood Hits	416	Shared Neighborhood Hits	95
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MPDZ_MOUSE
θ value	0.0961366 (rank : 169)	NC score	0.153721 (rank : 142)
Query Neighborhood Hits	258	Target Neighborhood Hits	298	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

VPS54_MOUSE
θ value	0.0961366 (rank : 170)	NC score	0.021849 (rank : 349)
Query Neighborhood Hits	258	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

INADL_HUMAN
θ value	0.125558 (rank : 171)	NC score	0.148334 (rank : 150)
Query Neighborhood Hits	258	Target Neighborhood Hits	260	Shared Neighborhood Hits	114
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

PAR3L_HUMAN
θ value	0.125558 (rank : 172)	NC score	0.137485 (rank : 158)
Query Neighborhood Hits	258	Target Neighborhood Hits	297	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDLI7_HUMAN
θ value	0.125558 (rank : 173)	NC score	0.082894 (rank : 224)
Query Neighborhood Hits	258	Target Neighborhood Hits	547	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD1_HUMAN
θ value	0.125558 (rank : 174)	NC score	0.152498 (rank : 144)
Query Neighborhood Hits	258	Target Neighborhood Hits	190	Shared Neighborhood Hits	110
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

RHPN1_HUMAN
θ value	0.125558 (rank : 175)	NC score	0.139179 (rank : 156)
Query Neighborhood Hits	258	Target Neighborhood Hits	158	Shared Neighborhood Hits	103
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

TX1B3_HUMAN
θ value	0.125558 (rank : 176)	NC score	0.167517 (rank : 131)
Query Neighborhood Hits	258	Target Neighborhood Hits	161	Shared Neighborhood Hits	104
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.125558 (rank : 177)	NC score	0.167566 (rank : 130)
Query Neighborhood Hits	258	Target Neighborhood Hits	158	Shared Neighborhood Hits	104
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

ZO2_MOUSE
θ value	0.125558 (rank : 178)	NC score	0.118366 (rank : 189)
Query Neighborhood Hits	258	Target Neighborhood Hits	296	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

MPDZ_HUMAN
θ value	0.163984 (rank : 179)	NC score	0.151011 (rank : 146)
Query Neighborhood Hits	258	Target Neighborhood Hits	261	Shared Neighborhood Hits	114
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PDLI2_MOUSE
θ value	0.163984 (rank : 180)	NC score	0.149367 (rank : 149)
Query Neighborhood Hits	258	Target Neighborhood Hits	220	Shared Neighborhood Hits	108
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI7_MOUSE
θ value	0.163984 (rank : 181)	NC score	0.082807 (rank : 225)
Query Neighborhood Hits	258	Target Neighborhood Hits	279	Shared Neighborhood Hits	84
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PZRN4_HUMAN
θ value	0.163984 (rank : 182)	NC score	0.120332 (rank : 186)
Query Neighborhood Hits	258	Target Neighborhood Hits	438	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

CDKN3_HUMAN
θ value	0.21417 (rank : 183)	NC score	0.083889 (rank : 222)
Query Neighborhood Hits	258	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

DUS1_HUMAN
θ value	0.21417 (rank : 184)	NC score	0.039923 (rank : 334)
Query Neighborhood Hits	258	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS1_MOUSE
θ value	0.21417 (rank : 185)	NC score	0.039148 (rank : 335)
Query Neighborhood Hits	258	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS23_HUMAN
θ value	0.21417 (rank : 186)	NC score	0.236685 (rank : 102)
Query Neighborhood Hits	258	Target Neighborhood Hits	98	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

GRIP2_HUMAN
θ value	0.21417 (rank : 187)	NC score	0.149514 (rank : 148)
Query Neighborhood Hits	258	Target Neighborhood Hits	256	Shared Neighborhood Hits	117
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

LAP4_HUMAN
θ value	0.21417 (rank : 188)	NC score	0.103712 (rank : 203)
Query Neighborhood Hits	258	Target Neighborhood Hits	608	Shared Neighborhood Hits	118
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PDLI4_MOUSE
θ value	0.21417 (rank : 189)	NC score	0.122556 (rank : 184)
Query Neighborhood Hits	258	Target Neighborhood Hits	233	Shared Neighborhood Hits	97
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

INADL_MOUSE
θ value	0.279714 (rank : 190)	NC score	0.150277 (rank : 147)
Query Neighborhood Hits	258	Target Neighborhood Hits	290	Shared Neighborhood Hits	116
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

RHPN1_MOUSE
θ value	0.279714 (rank : 191)	NC score	0.137371 (rank : 159)
Query Neighborhood Hits	258	Target Neighborhood Hits	154	Shared Neighborhood Hits	105
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

DLG1_HUMAN
θ value	0.365318 (rank : 192)	NC score	0.133934 (rank : 166)
Query Neighborhood Hits	258	Target Neighborhood Hits	290	Shared Neighborhood Hits	116
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	0.365318 (rank : 193)	NC score	0.130240 (rank : 174)
Query Neighborhood Hits	258	Target Neighborhood Hits	285	Shared Neighborhood Hits	109
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

GRIP1_HUMAN
θ value	0.365318 (rank : 194)	NC score	0.144933 (rank : 151)
Query Neighborhood Hits	258	Target Neighborhood Hits	231	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PDZD3_HUMAN
θ value	0.365318 (rank : 195)	NC score	0.140932 (rank : 154)
Query Neighborhood Hits	258	Target Neighborhood Hits	180	Shared Neighborhood Hits	108
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

ZO3_MOUSE
θ value	0.365318 (rank : 196)	NC score	0.129883 (rank : 175)
Query Neighborhood Hits	258	Target Neighborhood Hits	224	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

RGS12_HUMAN
θ value	0.47712 (rank : 197)	NC score	0.079204 (rank : 231)
Query Neighborhood Hits	258	Target Neighborhood Hits	333	Shared Neighborhood Hits	103
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

ZO3_HUMAN
θ value	0.47712 (rank : 198)	NC score	0.124743 (rank : 181)
Query Neighborhood Hits	258	Target Neighborhood Hits	219	Shared Neighborhood Hits	110
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ARHGC_HUMAN
θ value	0.62314 (rank : 199)	NC score	0.086510 (rank : 217)
Query Neighborhood Hits	258	Target Neighborhood Hits	351	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

DUS15_HUMAN
θ value	0.813845 (rank : 200)	NC score	0.027453 (rank : 339)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS2_MOUSE
θ value	0.813845 (rank : 201)	NC score	0.049656 (rank : 330)
Query Neighborhood Hits	258	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

LNX2_HUMAN
θ value	0.813845 (rank : 202)	NC score	0.129595 (rank : 176)
Query Neighborhood Hits	258	Target Neighborhood Hits	389	Shared Neighborhood Hits	114
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	0.813845 (rank : 203)	NC score	0.132200 (rank : 172)
Query Neighborhood Hits	258	Target Neighborhood Hits	407	Shared Neighborhood Hits	115
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

SDCB1_HUMAN
θ value	0.813845 (rank : 204)	NC score	0.083325 (rank : 223)
Query Neighborhood Hits	258	Target Neighborhood Hits	150	Shared Neighborhood Hits	96
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	0.813845 (rank : 205)	NC score	0.086827 (rank : 216)
Query Neighborhood Hits	258	Target Neighborhood Hits	144	Shared Neighborhood Hits	95
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB2_HUMAN
θ value	0.813845 (rank : 206)	NC score	0.075914 (rank : 236)
Query Neighborhood Hits	258	Target Neighborhood Hits	121	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

GRASP_HUMAN
θ value	1.06291 (rank : 207)	NC score	0.126308 (rank : 179)
Query Neighborhood Hits	258	Target Neighborhood Hits	147	Shared Neighborhood Hits	100
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

TP4A2_HUMAN
θ value	1.06291 (rank : 208)	NC score	0.089608 (rank : 213)
Query Neighborhood Hits	258	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	1.06291 (rank : 209)	NC score	0.089608 (rank : 214)
Query Neighborhood Hits	258	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

CC14B_MOUSE
θ value	1.38821 (rank : 210)	NC score	0.116637 (rank : 191)
Query Neighborhood Hits	258	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS22_MOUSE
θ value	1.38821 (rank : 211)	NC score	0.025707 (rank : 344)
Query Neighborhood Hits	258	Target Neighborhood Hits	57	Shared Neighborhood Hits	23
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

DUS6_HUMAN
θ value	1.38821 (rank : 212)	NC score	0.026934 (rank : 342)
Query Neighborhood Hits	258	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS6_MOUSE
θ value	1.38821 (rank : 213)	NC score	0.026946 (rank : 341)
Query Neighborhood Hits	258	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS7_HUMAN
θ value	1.38821 (rank : 214)	NC score	0.027423 (rank : 340)
Query Neighborhood Hits	258	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

GRIP1_MOUSE
θ value	1.38821 (rank : 215)	NC score	0.144921 (rank : 152)
Query Neighborhood Hits	258	Target Neighborhood Hits	241	Shared Neighborhood Hits	115
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MY18A_HUMAN
θ value	1.38821 (rank : 216)	NC score	0.025555 (rank : 345)
Query Neighborhood Hits	258	Target Neighborhood Hits	1929	Shared Neighborhood Hits	94
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PDLI5_MOUSE
θ value	1.38821 (rank : 217)	NC score	0.082686 (rank : 226)
Query Neighborhood Hits	258	Target Neighborhood Hits	287	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

MLL3_MOUSE
θ value	1.81305 (rank : 218)	NC score	0.017672 (rank : 351)
Query Neighborhood Hits	258	Target Neighborhood Hits	1399	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PDZD2_HUMAN
θ value	1.81305 (rank : 219)	NC score	0.135395 (rank : 163)
Query Neighborhood Hits	258	Target Neighborhood Hits	772	Shared Neighborhood Hits	117
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

TBX20_MOUSE
θ value	1.81305 (rank : 220)	NC score	0.001873 (rank : 361)
Query Neighborhood Hits	258	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

ARHGC_MOUSE
θ value	2.36792 (rank : 221)	NC score	0.085399 (rank : 219)
Query Neighborhood Hits	258	Target Neighborhood Hits	344	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

DUS13_MOUSE
θ value	2.36792 (rank : 222)	NC score	0.033937 (rank : 337)
Query Neighborhood Hits	258	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

GRASP_MOUSE
θ value	2.36792 (rank : 223)	NC score	0.123785 (rank : 182)
Query Neighborhood Hits	258	Target Neighborhood Hits	131	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

KRIT1_HUMAN
θ value	2.36792 (rank : 224)	NC score	0.068285 (rank : 257)
Query Neighborhood Hits	258	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

TENA_HUMAN
θ value	2.36792 (rank : 225)	NC score	0.055527 (rank : 311)
Query Neighborhood Hits	258	Target Neighborhood Hits	631	Shared Neighborhood Hits	22
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

USH2A_MOUSE
θ value	2.36792 (rank : 226)	NC score	0.068371 (rank : 256)
Query Neighborhood Hits	258	Target Neighborhood Hits	626	Shared Neighborhood Hits	22
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

DUS22_HUMAN
θ value	3.0926 (rank : 227)	NC score	0.024677 (rank : 346)
Query Neighborhood Hits	258	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

KRIT1_MOUSE
θ value	3.0926 (rank : 228)	NC score	0.064194 (rank : 264)
Query Neighborhood Hits	258	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

UNC5C_HUMAN
θ value	3.0926 (rank : 229)	NC score	0.011581 (rank : 354)
Query Neighborhood Hits	258	Target Neighborhood Hits	226	Shared Neighborhood Hits	8
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

DUS13_HUMAN
θ value	4.03905 (rank : 230)	NC score	0.038927 (rank : 336)
Query Neighborhood Hits	258	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

ENAM_HUMAN
θ value	4.03905 (rank : 231)	NC score	0.008991 (rank : 355)
Query Neighborhood Hits	258	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

LNX1_MOUSE
θ value	4.03905 (rank : 232)	NC score	0.119285 (rank : 187)
Query Neighborhood Hits	258	Target Neighborhood Hits	377	Shared Neighborhood Hits	108
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PAX7_HUMAN
θ value	4.03905 (rank : 233)	NC score	-0.003383 (rank : 363)
Query Neighborhood Hits	258	Target Neighborhood Hits	456	Shared Neighborhood Hits	5
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

PAX7_MOUSE
θ value	4.03905 (rank : 234)	NC score	-0.003435 (rank : 364)
Query Neighborhood Hits	258	Target Neighborhood Hits	422	Shared Neighborhood Hits	4
SwissProt Accessions	P47239, Q9ES16	Gene names	Pax7, Pax-7
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-7.

PDLI2_HUMAN
θ value	4.03905 (rank : 235)	NC score	0.141970 (rank : 153)
Query Neighborhood Hits	258	Target Neighborhood Hits	245	Shared Neighborhood Hits	112
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

TP4A1_HUMAN
θ value	4.03905 (rank : 236)	NC score	0.103964 (rank : 200)
Query Neighborhood Hits	258	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	4.03905 (rank : 237)	NC score	0.103964 (rank : 201)
Query Neighborhood Hits	258	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

ARHGB_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.094714 (rank : 207)
Query Neighborhood Hits	258	Target Neighborhood Hits	375	Shared Neighborhood Hits	115
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARMX5_HUMAN
θ value	5.27518 (rank : 239)	NC score	0.003246 (rank : 359)
Query Neighborhood Hits	258	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1M9, Q68DB4, Q9BVZ3, Q9H969	Gene names	ARMCX5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

MY18A_MOUSE
θ value	5.27518 (rank : 240)	NC score	0.026067 (rank : 343)
Query Neighborhood Hits	258	Target Neighborhood Hits	1989	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PDLI5_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.080486 (rank : 228)
Query Neighborhood Hits	258	Target Neighborhood Hits	322	Shared Neighborhood Hits	96
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

RPGF6_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.093359 (rank : 208)
Query Neighborhood Hits	258	Target Neighborhood Hits	266	Shared Neighborhood Hits	113
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SHAN1_HUMAN
θ value	5.27518 (rank : 243)	NC score	0.033532 (rank : 338)
Query Neighborhood Hits	258	Target Neighborhood Hits	1041	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

USH2A_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.071375 (rank : 250)
Query Neighborhood Hits	258	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ZO1_HUMAN
θ value	5.27518 (rank : 245)	NC score	0.112273 (rank : 195)
Query Neighborhood Hits	258	Target Neighborhood Hits	474	Shared Neighborhood Hits	114
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.112764 (rank : 194)
Query Neighborhood Hits	258	Target Neighborhood Hits	453	Shared Neighborhood Hits	112
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LRFN3_MOUSE
θ value	6.88961 (rank : 247)	NC score	0.011871 (rank : 353)
Query Neighborhood Hits	258	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

NF2L2_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.002174 (rank : 360)
Query Neighborhood Hits	258	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

PDE8A_MOUSE
θ value	6.88961 (rank : 249)	NC score	0.001724 (rank : 362)
Query Neighborhood Hits	258	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O88502	Gene names	Pde8a, Pde8
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17) (MMPDE8).

PSCBP_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.085437 (rank : 218)
Query Neighborhood Hits	258	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

TP4A3_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.084669 (rank : 220)
Query Neighborhood Hits	258	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

APC_HUMAN
θ value	8.99809 (rank : 252)	NC score	0.005991 (rank : 357)
Query Neighborhood Hits	258	Target Neighborhood Hits	603	Shared Neighborhood Hits	12
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	8.99809 (rank : 253)	NC score	0.004747 (rank : 358)
Query Neighborhood Hits	258	Target Neighborhood Hits	441	Shared Neighborhood Hits	13
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CING_HUMAN
θ value	8.99809 (rank : 254)	NC score	0.007757 (rank : 356)
Query Neighborhood Hits	258	Target Neighborhood Hits	1275	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

DUS11_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.021956 (rank : 348)
Query Neighborhood Hits	258	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

DUS12_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.020545 (rank : 350)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

DUS19_MOUSE
θ value	8.99809 (rank : 257)	NC score	0.024365 (rank : 347)
Query Neighborhood Hits	258	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

LRFN3_HUMAN
θ value	8.99809 (rank : 258)	NC score	0.012011 (rank : 352)
Query Neighborhood Hits	258	Target Neighborhood Hits	444	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

AFAD_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.087210 (rank : 215)
Query Neighborhood Hits	258	Target Neighborhood Hits	689	Shared Neighborhood Hits	97
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

APBA1_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.062563 (rank : 272)
Query Neighborhood Hits	258	Target Neighborhood Hits	325	Shared Neighborhood Hits	85
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

APBA2_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.059360 (rank : 289)
Query Neighborhood Hits	258	Target Neighborhood Hits	220	Shared Neighborhood Hits	81
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.058564 (rank : 294)
Query Neighborhood Hits	258	Target Neighborhood Hits	219	Shared Neighborhood Hits	81
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.059091 (rank : 290)
Query Neighborhood Hits	258	Target Neighborhood Hits	201	Shared Neighborhood Hits	75
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.057850 (rank : 296)
Query Neighborhood Hits	258	Target Neighborhood Hits	174	Shared Neighborhood Hits	76
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

CA106_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.059669 (rank : 286)
Query Neighborhood Hits	258	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.058856 (rank : 292)
Query Neighborhood Hits	258	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CC14A_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.098395 (rank : 206)
Query Neighborhood Hits	258	Target Neighborhood Hits	133	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.101321 (rank : 204)
Query Neighborhood Hits	258	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14B_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.114064 (rank : 193)
Query Neighborhood Hits	258	Target Neighborhood Hits	114	Shared Neighborhood Hits	73
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CNTN1_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.051937 (rank : 323)
Query Neighborhood Hits	258	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN1_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.053052 (rank : 320)
Query Neighborhood Hits	258	Target Neighborhood Hits	422	Shared Neighborhood Hits	18
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.056018 (rank : 309)
Query Neighborhood Hits	258	Target Neighborhood Hits	440	Shared Neighborhood Hits	19
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.055826 (rank : 310)
Query Neighborhood Hits	258	Target Neighborhood Hits	450	Shared Neighborhood Hits	19
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN3_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.051199 (rank : 326)
Query Neighborhood Hits	258	Target Neighborhood Hits	447	Shared Neighborhood Hits	22
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN5_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.057768 (rank : 298)
Query Neighborhood Hits	258	Target Neighborhood Hits	446	Shared Neighborhood Hits	21
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN5_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.056459 (rank : 307)
Query Neighborhood Hits	258	Target Neighborhood Hits	434	Shared Neighborhood Hits	20
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN6_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.050352 (rank : 327)
Query Neighborhood Hits	258	Target Neighborhood Hits	422	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CO7A1_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.056590 (rank : 305)
Query Neighborhood Hits	258	Target Neighborhood Hits	807	Shared Neighborhood Hits	26
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COCA1_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.071596 (rank : 249)
Query Neighborhood Hits	258	Target Neighborhood Hits	458	Shared Neighborhood Hits	28
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.073426 (rank : 246)
Query Neighborhood Hits	258	Target Neighborhood Hits	467	Shared Neighborhood Hits	24
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.053148 (rank : 319)
Query Neighborhood Hits	258	Target Neighborhood Hits	427	Shared Neighborhood Hits	21
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.059805 (rank : 282)
Query Neighborhood Hits	258	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DCC_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.082254 (rank : 227)
Query Neighborhood Hits	258	Target Neighborhood Hits	583	Shared Neighborhood Hits	32
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.080033 (rank : 230)
Query Neighborhood Hits	258	Target Neighborhood Hits	896	Shared Neighborhood Hits	38
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DLG5_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.077207 (rank : 233)
Query Neighborhood Hits	258	Target Neighborhood Hits	1088	Shared Neighborhood Hits	113
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DSCAM_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.059674 (rank : 285)
Query Neighborhood Hits	258	Target Neighborhood Hits	524	Shared Neighborhood Hits	23
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.059520 (rank : 288)
Query Neighborhood Hits	258	Target Neighborhood Hits	589	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DVL1L_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.056826 (rank : 304)
Query Neighborhood Hits	258	Target Neighborhood Hits	146	Shared Neighborhood Hits	74
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.061167 (rank : 274)
Query Neighborhood Hits	258	Target Neighborhood Hits	158	Shared Neighborhood Hits	75
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.059641 (rank : 287)
Query Neighborhood Hits	258	Target Neighborhood Hits	146	Shared Neighborhood Hits	73
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL2_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.057425 (rank : 300)
Query Neighborhood Hits	258	Target Neighborhood Hits	223	Shared Neighborhood Hits	72
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.057407 (rank : 301)
Query Neighborhood Hits	258	Target Neighborhood Hits	233	Shared Neighborhood Hits	72
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.060755 (rank : 278)
Query Neighborhood Hits	258	Target Neighborhood Hits	194	Shared Neighborhood Hits	71
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.060236 (rank : 280)
Query Neighborhood Hits	258	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

EM55_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.051260 (rank : 325)
Query Neighborhood Hits	258	Target Neighborhood Hits	228	Shared Neighborhood Hits	74
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

FINC_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.111756 (rank : 196)
Query Neighborhood Hits	258	Target Neighborhood Hits	302	Shared Neighborhood Hits	26
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.110686 (rank : 197)
Query Neighborhood Hits	258	Target Neighborhood Hits	309	Shared Neighborhood Hits	25
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FNDC3_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.099518 (rank : 205)
Query Neighborhood Hits	258	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.093012 (rank : 210)
Query Neighborhood Hits	258	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ITB4_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.062846 (rank : 271)
Query Neighborhood Hits	258	Target Neighborhood Hits	458	Shared Neighborhood Hits	20
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

K1849_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.090921 (rank : 212)
Query Neighborhood Hits	258	Target Neighborhood Hits	220	Shared Neighborhood Hits	89
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.092854 (rank : 211)
Query Neighborhood Hits	258	Target Neighborhood Hits	335	Shared Neighborhood Hits	94
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

L1CAM_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.059993 (rank : 281)
Query Neighborhood Hits	258	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.060894 (rank : 276)
Query Neighborhood Hits	258	Target Neighborhood Hits	457	Shared Neighborhood Hits	26
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LNX1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.115334 (rank : 192)
Query Neighborhood Hits	258	Target Neighborhood Hits	379	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAMC1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.052954 (rank : 321)
Query Neighborhood Hits	258	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.053924 (rank : 314)
Query Neighborhood Hits	258	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC2_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.071204 (rank : 251)
Query Neighborhood Hits	258	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.074250 (rank : 244)
Query Neighborhood Hits	258	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MDGA1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.056468 (rank : 306)
Query Neighborhood Hits	258	Target Neighborhood Hits	358	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MPP3_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.058855 (rank : 293)
Query Neighborhood Hits	258	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.059782 (rank : 283)
Query Neighborhood Hits	258	Target Neighborhood Hits	165	Shared Neighborhood Hits	75
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.068873 (rank : 255)
Query Neighborhood Hits	258	Target Neighborhood Hits	205	Shared Neighborhood Hits	82
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP4_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.057432 (rank : 299)
Query Neighborhood Hits	258	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP5_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.060729 (rank : 279)
Query Neighborhood Hits	258	Target Neighborhood Hits	231	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.060765 (rank : 277)
Query Neighborhood Hits	258	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MYOM1_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.050200 (rank : 328)
Query Neighborhood Hits	258	Target Neighborhood Hits	405	Shared Neighborhood Hits	16
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

MYOM1_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.053800 (rank : 315)
Query Neighborhood Hits	258	Target Neighborhood Hits	415	Shared Neighborhood Hits	22
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NEB1_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.073541 (rank : 245)
Query Neighborhood Hits	258	Target Neighborhood Hits	829	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.075626 (rank : 237)
Query Neighborhood Hits	258	Target Neighborhood Hits	883	Shared Neighborhood Hits	77
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.073290 (rank : 248)
Query Neighborhood Hits	258	Target Neighborhood Hits	889	Shared Neighborhood Hits	78
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEO1_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.077545 (rank : 232)
Query Neighborhood Hits	258	Target Neighborhood Hits	530	Shared Neighborhood Hits	28
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.080284 (rank : 229)
Query Neighborhood Hits	258	Target Neighborhood Hits	523	Shared Neighborhood Hits	29
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NFASC_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.052261 (rank : 322)
Query Neighborhood Hits	258	Target Neighborhood Hits	497	Shared Neighborhood Hits	20
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NFASC_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.050106 (rank : 329)
Query Neighborhood Hits	258	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

NOS1_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.066296 (rank : 260)
Query Neighborhood Hits	258	Target Neighborhood Hits	218	Shared Neighborhood Hits	87
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS1_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.057069 (rank : 303)
Query Neighborhood Hits	258	Target Neighborhood Hits	155	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NRCAM_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.057866 (rank : 295)
Query Neighborhood Hits	258	Target Neighborhood Hits	439	Shared Neighborhood Hits	19
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.059747 (rank : 284)
Query Neighborhood Hits	258	Target Neighborhood Hits	432	Shared Neighborhood Hits	21
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PAR6A_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.053627 (rank : 316)
Query Neighborhood Hits	258	Target Neighborhood Hits	119	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.054235 (rank : 313)
Query Neighborhood Hits	258	Target Neighborhood Hits	115	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6B_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.061427 (rank : 273)
Query Neighborhood Hits	258	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.061042 (rank : 275)
Query Neighborhood Hits	258	Target Neighborhood Hits	128	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.063535 (rank : 268)
Query Neighborhood Hits	258	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.063547 (rank : 267)
Query Neighborhood Hits	258	Target Neighborhood Hits	121	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PARD3_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.126994 (rank : 178)
Query Neighborhood Hits	258	Target Neighborhood Hits	312	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.125085 (rank : 180)
Query Neighborhood Hits	258	Target Neighborhood Hits	290	Shared Neighborhood Hits	101
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDC6I_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.051625 (rank : 324)
Query Neighborhood Hits	258	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDC6I_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.054364 (rank : 312)
Query Neighborhood Hits	258	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDZK4_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.073361 (rank : 247)
Query Neighborhood Hits	258	Target Neighborhood Hits	165	Shared Neighborhood Hits	78
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.074811 (rank : 240)
Query Neighborhood Hits	258	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PICK1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.076757 (rank : 234)
Query Neighborhood Hits	258	Target Neighborhood Hits	132	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.075270 (rank : 238)
Query Neighborhood Hits	258	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PSCBP_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.093062 (rank : 209)
Query Neighborhood Hits	258	Target Neighborhood Hits	118	Shared Neighborhood Hits	97
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PTEN_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.074460 (rank : 242)
Query Neighborhood Hits	258	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.074459 (rank : 243)
Query Neighborhood Hits	258	Target Neighborhood Hits	73	Shared Neighborhood Hits	42
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

RES18_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.057291 (rank : 302)
Query Neighborhood Hits	258	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

RHPN2_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.053300 (rank : 317)
Query Neighborhood Hits	258	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RHPN2_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.064688 (rank : 263)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RPGF2_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.071050 (rank : 252)
Query Neighborhood Hits	258	Target Neighborhood Hits	242	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SDCB2_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.069204 (rank : 254)
Query Neighborhood Hits	258	Target Neighborhood Hits	118	Shared Neighborhood Hits	79
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDK1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.065840 (rank : 261)
Query Neighborhood Hits	258	Target Neighborhood Hits	511	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.066803 (rank : 258)
Query Neighborhood Hits	258	Target Neighborhood Hits	495	Shared Neighborhood Hits	26
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.066671 (rank : 259)
Query Neighborhood Hits	258	Target Neighborhood Hits	495	Shared Neighborhood Hits	26
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.069414 (rank : 253)
Query Neighborhood Hits	258	Target Neighborhood Hits	480	Shared Neighborhood Hits	26
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SHAN2_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.053167 (rank : 318)
Query Neighborhood Hits	258	Target Neighborhood Hits	346	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

STXB4_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.084199 (rank : 221)
Query Neighborhood Hits	258	Target Neighborhood Hits	616	Shared Neighborhood Hits	75
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.074976 (rank : 239)
Query Neighborhood Hits	258	Target Neighborhood Hits	629	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TARSH_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.057824 (rank : 297)
Query Neighborhood Hits	258	Target Neighborhood Hits	768	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TENN_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.065249 (rank : 262)
Query Neighborhood Hits	258	Target Neighborhood Hits	453	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.076421 (rank : 235)
Query Neighborhood Hits	258	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.064090 (rank : 265)
Query Neighborhood Hits	258	Target Neighborhood Hits	526	Shared Neighborhood Hits	21
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.063891 (rank : 266)
Query Neighborhood Hits	258	Target Neighborhood Hits	531	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TP4A3_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.074482 (rank : 241)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

Hits sorted by NC score

PTN3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	258	Target Neighborhood Hits	258	Shared Neighborhood Hits	258
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
NC score	0.990853 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	258	Target Neighborhood Hits	303	Shared Neighborhood Hits	216
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN21_HUMAN
NC score	0.930099 (rank : 3)	θ value	1.61718e-49 (rank : 16)
Query Neighborhood Hits	258	Target Neighborhood Hits	143	Shared Neighborhood Hits	103
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
NC score	0.930007 (rank : 4)	θ value	1.61718e-49 (rank : 17)
Query Neighborhood Hits	258	Target Neighborhood Hits	155	Shared Neighborhood Hits	102
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN14_MOUSE
NC score	0.927464 (rank : 5)	θ value	3.1488e-53 (rank : 12)
Query Neighborhood Hits	258	Target Neighborhood Hits	142	Shared Neighborhood Hits	112
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.926253 (rank : 6)	θ value	1.51013e-55 (rank : 11)
Query Neighborhood Hits	258	Target Neighborhood Hits	163	Shared Neighborhood Hits	113
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.875964 (rank : 7)	θ value	2.1121e-49 (rank : 20)
Query Neighborhood Hits	258	Target Neighborhood Hits	426	Shared Neighborhood Hits	219
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.867212 (rank : 8)	θ value	5.20228e-48 (rank : 25)
Query Neighborhood Hits	258	Target Neighborhood Hits	471	Shared Neighborhood Hits	218
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN1_MOUSE
NC score	0.771220 (rank : 9)	θ value	6.35935e-46 (rank : 26)
Query Neighborhood Hits	258	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN1_HUMAN
NC score	0.770928 (rank : 10)	θ value	4.122e-45 (rank : 29)
Query Neighborhood Hits	258	Target Neighborhood Hits	84	Shared Neighborhood Hits	72
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN2_MOUSE
NC score	0.770539 (rank : 11)	θ value	3.04986e-48 (rank : 22)
Query Neighborhood Hits	258	Target Neighborhood Hits	107	Shared Neighborhood Hits	67
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN2_HUMAN
NC score	0.770347 (rank : 12)	θ value	3.04986e-48 (rank : 21)
Query Neighborhood Hits	258	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN18_HUMAN
NC score	0.768011 (rank : 13)	θ value	5.57106e-42 (rank : 36)
Query Neighborhood Hits	258	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
NC score	0.766138 (rank : 14)	θ value	2.76489e-41 (rank : 42)
Query Neighborhood Hits	258	Target Neighborhood Hits	134	Shared Neighborhood Hits	72
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN7_MOUSE
NC score	0.761755 (rank : 15)	θ value	4.568e-36 (rank : 67)
Query Neighborhood Hits	258	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.760818 (rank : 16)	θ value	1.12514e-34 (rank : 73)
Query Neighborhood Hits	258	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN22_HUMAN
NC score	0.758942 (rank : 17)	θ value	4.71619e-41 (rank : 44)
Query Neighborhood Hits	258	Target Neighborhood Hits	109	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN12_HUMAN
NC score	0.757231 (rank : 18)	θ value	2.67802e-36 (rank : 66)
Query Neighborhood Hits	258	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
NC score	0.756713 (rank : 19)	θ value	7.79185e-36 (rank : 68)
Query Neighborhood Hits	258	Target Neighborhood Hits	123	Shared Neighborhood Hits	67
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRO_HUMAN
NC score	0.754336 (rank : 20)	θ value	5.57106e-42 (rank : 39)
Query Neighborhood Hits	258	Target Neighborhood Hits	139	Shared Neighborhood Hits	73
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTN9_MOUSE
NC score	0.752538 (rank : 21)	θ value	6.15952e-41 (rank : 45)
Query Neighborhood Hits	258	Target Neighborhood Hits	78	Shared Neighborhood Hits	64
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_MOUSE
NC score	0.752413 (rank : 22)	θ value	8.32485e-38 (rank : 64)
Query Neighborhood Hits	258	Target Neighborhood Hits	179	Shared Neighborhood Hits	68
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN9_HUMAN
NC score	0.752345 (rank : 23)	θ value	2.76489e-41 (rank : 43)
Query Neighborhood Hits	258	Target Neighborhood Hits	79	Shared Neighborhood Hits	64
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN5_MOUSE
NC score	0.751647 (rank : 24)	θ value	5.77852e-31 (rank : 85)
Query Neighborhood Hits	258	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPR2_HUMAN
NC score	0.751375 (rank : 25)	θ value	1.20211e-36 (rank : 65)
Query Neighborhood Hits	258	Target Neighborhood Hits	103	Shared Neighborhood Hits	68
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTN5_HUMAN
NC score	0.750426 (rank : 26)	θ value	1.02001e-27 (rank : 89)
Query Neighborhood Hits	258	Target Neighborhood Hits	80	Shared Neighborhood Hits	68
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPR2_MOUSE
NC score	0.749898 (rank : 27)	θ value	2.19075e-38 (rank : 61)
Query Neighborhood Hits	258	Target Neighborhood Hits	120	Shared Neighborhood Hits	68
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

CD45_MOUSE
NC score	0.748587 (rank : 28)	θ value	2.86122e-38 (rank : 62)
Query Neighborhood Hits	258	Target Neighborhood Hits	178	Shared Neighborhood Hits	68
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRR_HUMAN
NC score	0.747854 (rank : 29)	θ value	3.3877e-31 (rank : 84)
Query Neighborhood Hits	258	Target Neighborhood Hits	77	Shared Neighborhood Hits	66
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
NC score	0.747496 (rank : 30)	θ value	7.54701e-31 (rank : 86)
Query Neighborhood Hits	258	Target Neighborhood Hits	84	Shared Neighborhood Hits	69
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRE_HUMAN
NC score	0.747485 (rank : 31)	θ value	2.11701e-41 (rank : 41)
Query Neighborhood Hits	258	Target Neighborhood Hits	92	Shared Neighborhood Hits	70
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.746987 (rank : 32)	θ value	3.99248e-40 (rank : 51)
Query Neighborhood Hits	258	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRE_MOUSE
NC score	0.746816 (rank : 33)	θ value	4.41421e-39 (rank : 59)
Query Neighborhood Hits	258	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_MOUSE
NC score	0.746515 (rank : 34)	θ value	3.99248e-40 (rank : 52)
Query Neighborhood Hits	258	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRN_HUMAN
NC score	0.745686 (rank : 35)	θ value	1.32909e-35 (rank : 70)
Query Neighborhood Hits	258	Target Neighborhood Hits	156	Shared Neighborhood Hits	67
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

CD45_HUMAN
NC score	0.743017 (rank : 36)	θ value	9.83387e-39 (rank : 60)
Query Neighborhood Hits	258	Target Neighborhood Hits	243	Shared Neighborhood Hits	68
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRN_MOUSE
NC score	0.742314 (rank : 37)	θ value	2.26708e-35 (rank : 71)
Query Neighborhood Hits	258	Target Neighborhood Hits	240	Shared Neighborhood Hits	68
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRJ_MOUSE
NC score	0.733629 (rank : 38)	θ value	1.19932e-44 (rank : 30)
Query Neighborhood Hits	258	Target Neighborhood Hits	188	Shared Neighborhood Hits	74
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRJ_HUMAN
NC score	0.730323 (rank : 39)	θ value	1.41672e-45 (rank : 27)
Query Neighborhood Hits	258	Target Neighborhood Hits	207	Shared Neighborhood Hits	78
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRV_MOUSE
NC score	0.723723 (rank : 40)	θ value	5.21438e-40 (rank : 54)
Query Neighborhood Hits	258	Target Neighborhood Hits	179	Shared Neighborhood Hits	69
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN6_HUMAN
NC score	0.720711 (rank : 41)	θ value	8.04462e-41 (rank : 46)
Query Neighborhood Hits	258	Target Neighborhood Hits	234	Shared Neighborhood Hits	72
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
NC score	0.718515 (rank : 42)	θ value	2.11701e-41 (rank : 40)
Query Neighborhood Hits	258	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRB_HUMAN
NC score	0.703946 (rank : 43)	θ value	4.55743e-44 (rank : 32)
Query Neighborhood Hits	258	Target Neighborhood Hits	242	Shared Neighborhood Hits	75
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTN11_MOUSE
NC score	0.700935 (rank : 44)	θ value	6.81017e-40 (rank : 55)
Query Neighborhood Hits	258	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.700870 (rank : 45)	θ value	1.51715e-39 (rank : 58)
Query Neighborhood Hits	258	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTPRK_HUMAN
NC score	0.699081 (rank : 46)	θ value	5.57106e-42 (rank : 38)
Query Neighborhood Hits	258	Target Neighborhood Hits	228	Shared Neighborhood Hits	67
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
NC score	0.697407 (rank : 47)	θ value	3.26607e-42 (rank : 35)
Query Neighborhood Hits	258	Target Neighborhood Hits	223	Shared Neighborhood Hits	67
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRT_HUMAN
NC score	0.693842 (rank : 48)	θ value	2.34062e-40 (rank : 49)
Query Neighborhood Hits	258	Target Neighborhood Hits	217	Shared Neighborhood Hits	67
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.693841 (rank : 49)	θ value	2.34062e-40 (rank : 50)
Query Neighborhood Hits	258	Target Neighborhood Hits	219	Shared Neighborhood Hits	67
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
NC score	0.686403 (rank : 50)	θ value	1.46948e-34 (rank : 76)
Query Neighborhood Hits	258	Target Neighborhood Hits	237	Shared Neighborhood Hits	70
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_MOUSE
NC score	0.683051 (rank : 51)	θ value	6.81017e-40 (rank : 56)
Query Neighborhood Hits	258	Target Neighborhood Hits	238	Shared Neighborhood Hits	68
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.681449 (rank : 52)	θ value	5.21438e-40 (rank : 53)
Query Neighborhood Hits	258	Target Neighborhood Hits	244	Shared Neighborhood Hits	68
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRG_HUMAN
NC score	0.674474 (rank : 53)	θ value	8.89434e-40 (rank : 57)
Query Neighborhood Hits	258	Target Neighborhood Hits	231	Shared Neighborhood Hits	63
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRZ_HUMAN
NC score	0.674341 (rank : 54)	θ value	1.01765e-35 (rank : 69)
Query Neighborhood Hits	258	Target Neighborhood Hits	255	Shared Neighborhood Hits	66
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_MOUSE
NC score	0.672437 (rank : 55)	θ value	8.04462e-41 (rank : 48)
Query Neighborhood Hits	258	Target Neighborhood Hits	260	Shared Neighborhood Hits	68
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTN23_HUMAN
NC score	0.660635 (rank : 56)	θ value	8.61488e-35 (rank : 72)
Query Neighborhood Hits	258	Target Neighborhood Hits	646	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
NC score	0.660083 (rank : 57)	θ value	2.50655e-34 (rank : 77)
Query Neighborhood Hits	258	Target Neighborhood Hits	726	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

E41L5_HUMAN
NC score	0.653987 (rank : 58)	θ value	5.37103e-53 (rank : 13)
Query Neighborhood Hits	258	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
NC score	0.653845 (rank : 59)	θ value	1.46268e-50 (rank : 14)
Query Neighborhood Hits	258	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LA_HUMAN
NC score	0.653753 (rank : 60)	θ value	2.1121e-49 (rank : 18)
Query Neighborhood Hits	258	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.653731 (rank : 61)	θ value	3.98324e-48 (rank : 23)
Query Neighborhood Hits	258	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FRMD5_MOUSE
NC score	0.651355 (rank : 62)	θ value	7.77379e-44 (rank : 33)
Query Neighborhood Hits	258	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.649968 (rank : 63)	θ value	2.04573e-44 (rank : 31)
Query Neighborhood Hits	258	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L3_HUMAN
NC score	0.649843 (rank : 64)	θ value	4.24587e-58 (rank : 7)
Query Neighborhood Hits	258	Target Neighborhood Hits	113	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41LB_HUMAN
NC score	0.649005 (rank : 65)	θ value	2.1121e-49 (rank : 19)
Query Neighborhood Hits	258	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41L1_MOUSE
NC score	0.648053 (rank : 66)	θ value	8.55514e-59 (rank : 3)
Query Neighborhood Hits	258	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_HUMAN
NC score	0.647611 (rank : 67)	θ value	1.11734e-58 (rank : 4)
Query Neighborhood Hits	258	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

41_MOUSE
NC score	0.645444 (rank : 68)	θ value	1.78386e-56 (rank : 10)
Query Neighborhood Hits	258	Target Neighborhood Hits	184	Shared Neighborhood Hits	50
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L1_HUMAN
NC score	0.644706 (rank : 69)	θ value	1.45929e-58 (rank : 6)
Query Neighborhood Hits	258	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_MOUSE
NC score	0.639702 (rank : 70)	θ value	1.23536e-57 (rank : 8)
Query Neighborhood Hits	258	Target Neighborhood Hits	250	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.638599 (rank : 71)	θ value	1.11734e-58 (rank : 5)
Query Neighborhood Hits	258	Target Neighborhood Hits	287	Shared Neighborhood Hits	53
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
NC score	0.621484 (rank : 72)	θ value	3.59435e-57 (rank : 9)
Query Neighborhood Hits	258	Target Neighborhood Hits	459	Shared Neighborhood Hits	52
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_MOUSE
NC score	0.599208 (rank : 73)	θ value	3.74554e-30 (rank : 87)
Query Neighborhood Hits	258	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.587294 (rank : 74)	θ value	1.4233e-29 (rank : 88)
Query Neighborhood Hits	258	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4B_HUMAN
NC score	0.555067 (rank : 75)	θ value	2.69047e-20 (rank : 91)
Query Neighborhood Hits	258	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.553843 (rank : 76)	θ value	1.5773e-20 (rank : 90)
Query Neighborhood Hits	258	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

MERL_MOUSE
NC score	0.547931 (rank : 77)	θ value	1.98606e-31 (rank : 83)
Query Neighborhood Hits	258	Target Neighborhood Hits	524	Shared Neighborhood Hits	54
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.547370 (rank : 78)	θ value	1.52067e-31 (rank : 82)
Query Neighborhood Hits	258	Target Neighborhood Hits	532	Shared Neighborhood Hits	54
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FRM4A_HUMAN
NC score	0.547302 (rank : 79)	θ value	4.74913e-17 (rank : 93)
Query Neighborhood Hits	258	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
NC score	0.546804 (rank : 80)	θ value	3.63628e-17 (rank : 92)
Query Neighborhood Hits	258	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

PTPRS_HUMAN
NC score	0.545062 (rank : 81)	θ value	6.58091e-43 (rank : 34)
Query Neighborhood Hits	258	Target Neighborhood Hits	472	Shared Neighborhood Hits	76
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

FARP1_HUMAN
NC score	0.540021 (rank : 82)	θ value	9.48078e-50 (rank : 15)
Query Neighborhood Hits	258	Target Neighborhood Hits	241	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PTPRD_HUMAN
NC score	0.534820 (rank : 83)	θ value	5.57106e-42 (rank : 37)
Query Neighborhood Hits	258	Target Neighborhood Hits	485	Shared Neighborhood Hits	78
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.531990 (rank : 84)	θ value	8.04462e-41 (rank : 47)
Query Neighborhood Hits	258	Target Neighborhood Hits	489	Shared Neighborhood Hits	76
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.525503 (rank : 85)	θ value	4.88048e-38 (rank : 63)
Query Neighborhood Hits	258	Target Neighborhood Hits	491	Shared Neighborhood Hits	78
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FARP2_HUMAN
NC score	0.524154 (rank : 86)	θ value	3.15612e-45 (rank : 28)
Query Neighborhood Hits	258	Target Neighborhood Hits	240	Shared Neighborhood Hits	52
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

EZRI_HUMAN
NC score	0.519687 (rank : 87)	θ value	8.06329e-33 (rank : 79)
Query Neighborhood Hits	258	Target Neighborhood Hits	663	Shared Neighborhood Hits	53
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FARP2_MOUSE
NC score	0.519509 (rank : 88)	θ value	3.98324e-48 (rank : 24)
Query Neighborhood Hits	258	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

EZRI_MOUSE
NC score	0.516305 (rank : 89)	θ value	6.17384e-33 (rank : 78)
Query Neighborhood Hits	258	Target Neighborhood Hits	693	Shared Neighborhood Hits	52
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.507562 (rank : 90)	θ value	1.12514e-34 (rank : 74)
Query Neighborhood Hits	258	Target Neighborhood Hits	741	Shared Neighborhood Hits	53
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.504762 (rank : 91)	θ value	1.12514e-34 (rank : 75)
Query Neighborhood Hits	258	Target Neighborhood Hits	773	Shared Neighborhood Hits	52
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

FRMD6_MOUSE
NC score	0.494706 (rank : 92)	θ value	2.69671e-12 (rank : 94)
Query Neighborhood Hits	258	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.489021 (rank : 93)	θ value	6.00763e-12 (rank : 95)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD1_HUMAN
NC score	0.481699 (rank : 94)	θ value	1.63604e-09 (rank : 96)
Query Neighborhood Hits	258	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

MOES_HUMAN
NC score	0.475113 (rank : 95)	θ value	8.91499e-32 (rank : 81)
Query Neighborhood Hits	258	Target Neighborhood Hits	892	Shared Neighborhood Hits	53
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
NC score	0.470113 (rank : 96)	θ value	4.00176e-32 (rank : 80)
Query Neighborhood Hits	258	Target Neighborhood Hits	923	Shared Neighborhood Hits	55
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

TLN1_HUMAN
NC score	0.301779 (rank : 97)	θ value	8.11959e-09 (rank : 97)
Query Neighborhood Hits	258	Target Neighborhood Hits	218	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.299491 (rank : 98)	θ value	8.11959e-09 (rank : 98)
Query Neighborhood Hits	258	Target Neighborhood Hits	213	Shared Neighborhood Hits	47
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.297967 (rank : 99)	θ value	3.08544e-08 (rank : 100)
Query Neighborhood Hits	258	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.294508 (rank : 100)	θ value	2.36244e-08 (rank : 99)
Query Neighborhood Hits	258	Target Neighborhood Hits	157	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

DUS23_MOUSE
NC score	0.245656 (rank : 101)	θ value	0.0961366 (rank : 166)
Query Neighborhood Hits	258	Target Neighborhood Hits	94	Shared Neighborhood Hits	66
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

DUS23_HUMAN
NC score	0.236685 (rank : 102)	θ value	0.21417 (rank : 186)
Query Neighborhood Hits	258	Target Neighborhood Hits	98	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

PDZ11_MOUSE
NC score	0.218443 (rank : 103)	θ value	1.43324e-05 (rank : 114)
Query Neighborhood Hits	258	Target Neighborhood Hits	154	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_HUMAN
NC score	0.216663 (rank : 104)	θ value	7.1131e-05 (rank : 123)
Query Neighborhood Hits	258	Target Neighborhood Hits	160	Shared Neighborhood Hits	112
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LIN7C_HUMAN
NC score	0.208431 (rank : 105)	θ value	1.09739e-05 (rank : 111)
Query Neighborhood Hits	258	Target Neighborhood Hits	198	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.208431 (rank : 106)	θ value	1.09739e-05 (rank : 112)
Query Neighborhood Hits	258	Target Neighborhood Hits	198	Shared Neighborhood Hits	116
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7B_HUMAN
NC score	0.206446 (rank : 107)	θ value	6.43352e-06 (rank : 107)
Query Neighborhood Hits	258	Target Neighborhood Hits	200	Shared Neighborhood Hits	116
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7A_HUMAN
NC score	0.206445 (rank : 108)	θ value	6.43352e-06 (rank : 105)
Query Neighborhood Hits	258	Target Neighborhood Hits	193	Shared Neighborhood Hits	116
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.206379 (rank : 109)	θ value	6.43352e-06 (rank : 106)
Query Neighborhood Hits	258	Target Neighborhood Hits	193	Shared Neighborhood Hits	116
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7B_MOUSE
NC score	0.206116 (rank : 110)	θ value	8.40245e-06 (rank : 109)
Query Neighborhood Hits	258	Target Neighborhood Hits	200	Shared Neighborhood Hits	116
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

SNTB2_HUMAN
NC score	0.205613 (rank : 111)	θ value	1.17247e-07 (rank : 101)
Query Neighborhood Hits	258	Target Neighborhood Hits	180	Shared Neighborhood Hits	113
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
NC score	0.205480 (rank : 112)	θ value	1.17247e-07 (rank : 102)
Query Neighborhood Hits	258	Target Neighborhood Hits	181	Shared Neighborhood Hits	113
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTA1_HUMAN
NC score	0.195299 (rank : 113)	θ value	8.40245e-06 (rank : 110)
Query Neighborhood Hits	258	Target Neighborhood Hits	186	Shared Neighborhood Hits	109
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
NC score	0.195282 (rank : 114)	θ value	1.09739e-05 (rank : 113)
Query Neighborhood Hits	258	Target Neighborhood Hits	170	Shared Neighborhood Hits	108
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTB1_HUMAN
NC score	0.194792 (rank : 115)	θ value	3.77169e-06 (rank : 103)
Query Neighborhood Hits	258	Target Neighborhood Hits	157	Shared Neighborhood Hits	106
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.194551 (rank : 116)	θ value	3.77169e-06 (rank : 104)
Query Neighborhood Hits	258	Target Neighborhood Hits	160	Shared Neighborhood Hits	106
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

GOPC_MOUSE
NC score	0.189746 (rank : 117)	θ value	9.29e-05 (rank : 125)
Query Neighborhood Hits	258	Target Neighborhood Hits	323	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PDZD7_HUMAN
NC score	0.189400 (rank : 118)	θ value	0.0252991 (rank : 156)
Query Neighborhood Hits	258	Target Neighborhood Hits	181	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

GOPC_HUMAN
NC score	0.188035 (rank : 119)	θ value	9.29e-05 (rank : 124)
Query Neighborhood Hits	258	Target Neighborhood Hits	377	Shared Neighborhood Hits	117
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SNTG1_MOUSE
NC score	0.186800 (rank : 120)	θ value	0.000158464 (rank : 130)
Query Neighborhood Hits	258	Target Neighborhood Hits	179	Shared Neighborhood Hits	113
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG2_MOUSE
NC score	0.186236 (rank : 121)	θ value	0.00102713 (rank : 137)
Query Neighborhood Hits	258	Target Neighborhood Hits	176	Shared Neighborhood Hits	112
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG1_HUMAN
NC score	0.186156 (rank : 122)	θ value	0.000121331 (rank : 128)
Query Neighborhood Hits	258	Target Neighborhood Hits	181	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SYJ2B_HUMAN
NC score	0.185001 (rank : 123)	θ value	0.0148317 (rank : 147)
Query Neighborhood Hits	258	Target Neighborhood Hits	162	Shared Neighborhood Hits	108
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

SNTG2_HUMAN
NC score	0.184667 (rank : 124)	θ value	0.00175202 (rank : 140)
Query Neighborhood Hits	258	Target Neighborhood Hits	191	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

WHRN_MOUSE
NC score	0.180378 (rank : 125)	θ value	0.000786445 (rank : 133)
Query Neighborhood Hits	258	Target Neighborhood Hits	412	Shared Neighborhood Hits	117
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WHRN_HUMAN
NC score	0.177841 (rank : 126)	θ value	0.00102713 (rank : 138)
Query Neighborhood Hits	258	Target Neighborhood Hits	325	Shared Neighborhood Hits	115
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

USH1C_HUMAN
NC score	0.171737 (rank : 127)	θ value	0.0193708 (rank : 152)
Query Neighborhood Hits	258	Target Neighborhood Hits	327	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

MAGI2_HUMAN
NC score	0.169241 (rank : 128)	θ value	3.19293e-05 (rank : 116)
Query Neighborhood Hits	258	Target Neighborhood Hits	373	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
NC score	0.169037 (rank : 129)	θ value	9.29e-05 (rank : 127)
Query Neighborhood Hits	258	Target Neighborhood Hits	370	Shared Neighborhood Hits	118
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

TX1B3_MOUSE
NC score	0.167566 (rank : 130)	θ value	0.125558 (rank : 177)
Query Neighborhood Hits	258	Target Neighborhood Hits	158	Shared Neighborhood Hits	104
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

TX1B3_HUMAN
NC score	0.167517 (rank : 131)	θ value	0.125558 (rank : 176)
Query Neighborhood Hits	258	Target Neighborhood Hits	161	Shared Neighborhood Hits	104
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

MAGI1_MOUSE
NC score	0.166075 (rank : 132)	θ value	4.1701e-05 (rank : 119)
Query Neighborhood Hits	258	Target Neighborhood Hits	403	Shared Neighborhood Hits	117
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
NC score	0.165512 (rank : 133)	θ value	9.29e-05 (rank : 126)
Query Neighborhood Hits	258	Target Neighborhood Hits	388	Shared Neighborhood Hits	116
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

NHERF_MOUSE
NC score	0.165266 (rank : 134)	θ value	0.0330416 (rank : 159)
Query Neighborhood Hits	258	Target Neighborhood Hits	195	Shared Neighborhood Hits	115
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
NC score	0.164766 (rank : 135)	θ value	0.00102713 (rank : 135)
Query Neighborhood Hits	258	Target Neighborhood Hits	197	Shared Neighborhood Hits	112
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHERF_HUMAN
NC score	0.164144 (rank : 136)	θ value	0.0193708 (rank : 151)
Query Neighborhood Hits	258	Target Neighborhood Hits	190	Shared Neighborhood Hits	115
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

USH1C_MOUSE
NC score	0.163024 (rank : 137)	θ value	0.0193708 (rank : 153)
Query Neighborhood Hits	258	Target Neighborhood Hits	557	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

NHRF2_MOUSE
NC score	0.161938 (rank : 138)	θ value	0.00102713 (rank : 136)
Query Neighborhood Hits	258	Target Neighborhood Hits	194	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

IL16_HUMAN
NC score	0.158664 (rank : 139)	θ value	0.00869519 (rank : 142)
Query Neighborhood Hits	258	Target Neighborhood Hits	207	Shared Neighborhood Hits	95
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IL16_MOUSE
NC score	0.158294 (rank : 140)	θ value	0.00175202 (rank : 139)
Query Neighborhood Hits	258	Target Neighborhood Hits	189	Shared Neighborhood Hits	94
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZD1_MOUSE
NC score	0.157901 (rank : 141)	θ value	0.0252991 (rank : 154)
Query Neighborhood Hits	258	Target Neighborhood Hits	191	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

MPDZ_MOUSE
NC score	0.153721 (rank : 142)	θ value	0.0961366 (rank : 169)
Query Neighborhood Hits	258	Target Neighborhood Hits	298	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

SYP2L_HUMAN
NC score	0.153198 (rank : 143)	θ value	6.43352e-06 (rank : 108)
Query Neighborhood Hits	258	Target Neighborhood Hits	400	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PDZD1_HUMAN
NC score	0.152498 (rank : 144)	θ value	0.125558 (rank : 174)
Query Neighborhood Hits	258	Target Neighborhood Hits	190	Shared Neighborhood Hits	110
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SYNP2_MOUSE
NC score	0.151921 (rank : 145)	θ value	4.1701e-05 (rank : 121)
Query Neighborhood Hits	258	Target Neighborhood Hits	252	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

MPDZ_HUMAN
NC score	0.151011 (rank : 146)	θ value	0.163984 (rank : 179)
Query Neighborhood Hits	258	Target Neighborhood Hits	261	Shared Neighborhood Hits	114
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

INADL_MOUSE
NC score	0.150277 (rank : 147)	θ value	0.279714 (rank : 190)
Query Neighborhood Hits	258	Target Neighborhood Hits	290	Shared Neighborhood Hits	116
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

GRIP2_HUMAN
NC score	0.149514 (rank : 148)	θ value	0.21417 (rank : 187)
Query Neighborhood Hits	258	Target Neighborhood Hits	256	Shared Neighborhood Hits	117
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

PDLI2_MOUSE
NC score	0.149367 (rank : 149)	θ value	0.163984 (rank : 180)
Query Neighborhood Hits	258	Target Neighborhood Hits	220	Shared Neighborhood Hits	108
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

INADL_HUMAN
NC score	0.148334 (rank : 150)	θ value	0.125558 (rank : 171)
Query Neighborhood Hits	258	Target Neighborhood Hits	260	Shared Neighborhood Hits	114
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

GRIP1_HUMAN
NC score	0.144933 (rank : 151)	θ value	0.365318 (rank : 194)
Query Neighborhood Hits	258	Target Neighborhood Hits	231	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
NC score	0.144921 (rank : 152)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	258	Target Neighborhood Hits	241	Shared Neighborhood Hits	115
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PDLI2_HUMAN
NC score	0.141970 (rank : 153)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	258	Target Neighborhood Hits	245	Shared Neighborhood Hits	112
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDZD3_HUMAN
NC score	0.140932 (rank : 154)	θ value	0.365318 (rank : 195)
Query Neighborhood Hits	258	Target Neighborhood Hits	180	Shared Neighborhood Hits	108
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

SYNP2_HUMAN
NC score	0.139638 (rank : 155)	θ value	4.1701e-05 (rank : 120)
Query Neighborhood Hits	258	Target Neighborhood Hits	323	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

RHPN1_HUMAN
NC score	0.139179 (rank : 156)	θ value	0.125558 (rank : 175)
Query Neighborhood Hits	258	Target Neighborhood Hits	158	Shared Neighborhood Hits	103
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

DLG4_MOUSE
NC score	0.137529 (rank : 157)	θ value	0.0193708 (rank : 149)
Query Neighborhood Hits	258	Target Neighborhood Hits	282	Shared Neighborhood Hits	111
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PAR3L_HUMAN
NC score	0.137485 (rank : 158)	θ value	0.125558 (rank : 172)
Query Neighborhood Hits	258	Target Neighborhood Hits	297	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

RHPN1_MOUSE
NC score	0.137371 (rank : 159)	θ value	0.279714 (rank : 191)
Query Neighborhood Hits	258	Target Neighborhood Hits	154	Shared Neighborhood Hits	105
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

DLG4_HUMAN
NC score	0.137365 (rank : 160)	θ value	0.0193708 (rank : 148)
Query Neighborhood Hits	258	Target Neighborhood Hits	286	Shared Neighborhood Hits	111
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PDLI3_HUMAN
NC score	0.137274 (rank : 161)	θ value	0.000461057 (rank : 131)
Query Neighborhood Hits	258	Target Neighborhood Hits	199	Shared Neighborhood Hits	101
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI1_MOUSE
NC score	0.136180 (rank : 162)	θ value	0.000158464 (rank : 129)
Query Neighborhood Hits	258	Target Neighborhood Hits	213	Shared Neighborhood Hits	86
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDZD2_HUMAN
NC score	0.135395 (rank : 163)	θ value	1.81305 (rank : 219)
Query Neighborhood Hits	258	Target Neighborhood Hits	772	Shared Neighborhood Hits	117
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PDLI3_MOUSE
NC score	0.134970 (rank : 164)	θ value	7.1131e-05 (rank : 122)
Query Neighborhood Hits	258	Target Neighborhood Hits	197	Shared Neighborhood Hits	97
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDZD3_MOUSE
NC score	0.134934 (rank : 165)	θ value	0.0252991 (rank : 155)
Query Neighborhood Hits	258	Target Neighborhood Hits	171	Shared Neighborhood Hits	109
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

DLG1_HUMAN
NC score	0.133934 (rank : 166)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	258	Target Neighborhood Hits	290	Shared Neighborhood Hits	116
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG3_MOUSE
NC score	0.133492 (rank : 167)	θ value	0.0431538 (rank : 161)
Query Neighborhood Hits	258	Target Neighborhood Hits	274	Shared Neighborhood Hits	110
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.133428 (rank : 168)	θ value	0.0431538 (rank : 160)
Query Neighborhood Hits	258	Target Neighborhood Hits	269	Shared Neighborhood Hits	110
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

SYP2L_MOUSE
NC score	0.133203 (rank : 169)	θ value	2.44474e-05 (rank : 115)
Query Neighborhood Hits	258	Target Neighborhood Hits	289	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

DLG2_MOUSE
NC score	0.133201 (rank : 170)	θ value	0.0330416 (rank : 158)
Query Neighborhood Hits	258	Target Neighborhood Hits	271	Shared Neighborhood Hits	107
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_HUMAN
NC score	0.132628 (rank : 171)	θ value	0.0330416 (rank : 157)
Query Neighborhood Hits	258	Target Neighborhood Hits	279	Shared Neighborhood Hits	108
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LNX2_MOUSE
NC score	0.132200 (rank : 172)	θ value	0.813845 (rank : 203)
Query Neighborhood Hits	258	Target Neighborhood Hits	407	Shared Neighborhood Hits	115
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PDLI1_HUMAN
NC score	0.130895 (rank : 173)	θ value	0.000786445 (rank : 132)
Query Neighborhood Hits	258	Target Neighborhood Hits	242	Shared Neighborhood Hits	88
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

DLG1_MOUSE
NC score	0.130240 (rank : 174)	θ value	0.365318 (rank : 193)
Query Neighborhood Hits	258	Target Neighborhood Hits	285	Shared Neighborhood Hits	109
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

ZO3_MOUSE
NC score	0.129883 (rank : 175)	θ value	0.365318 (rank : 196)
Query Neighborhood Hits	258	Target Neighborhood Hits	224	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

LNX2_HUMAN
NC score	0.129595 (rank : 176)	θ value	0.813845 (rank : 202)
Query Neighborhood Hits	258	Target Neighborhood Hits	389	Shared Neighborhood Hits	114
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

APXL_HUMAN
NC score	0.128338 (rank : 177)	θ value	0.00102713 (rank : 134)
Query Neighborhood Hits	258	Target Neighborhood Hits	553	Shared Neighborhood Hits	78
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PARD3_HUMAN
NC score	0.126994 (rank : 178)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	258	Target Neighborhood Hits	312	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

GRASP_HUMAN
NC score	0.126308 (rank : 179)	θ value	1.06291 (rank : 207)
Query Neighborhood Hits	258	Target Neighborhood Hits	147	Shared Neighborhood Hits	100
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PARD3_MOUSE
NC score	0.125085 (rank : 180)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	258	Target Neighborhood Hits	290	Shared Neighborhood Hits	101
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

ZO3_HUMAN
NC score	0.124743 (rank : 181)	θ value	0.47712 (rank : 198)
Query Neighborhood Hits	258	Target Neighborhood Hits	219	Shared Neighborhood Hits	110
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

GRASP_MOUSE
NC score	0.123785 (rank : 182)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	258	Target Neighborhood Hits	131	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PDLI4_HUMAN
NC score	0.123432 (rank : 183)	θ value	0.0431538 (rank : 162)
Query Neighborhood Hits	258	Target Neighborhood Hits	245	Shared Neighborhood Hits	96
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
NC score	0.122556 (rank : 184)	θ value	0.21417 (rank : 189)
Query Neighborhood Hits	258	Target Neighborhood Hits	233	Shared Neighborhood Hits	97
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

ZO2_HUMAN
NC score	0.121942 (rank : 185)	θ value	0.0431538 (rank : 163)
Query Neighborhood Hits	258	Target Neighborhood Hits	289	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PZRN4_HUMAN
NC score	0.120332 (rank : 186)	θ value	0.163984 (rank : 182)
Query Neighborhood Hits	258	Target Neighborhood Hits	438	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

LNX1_MOUSE
NC score	0.119285 (rank : 187)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	258	Target Neighborhood Hits	377	Shared Neighborhood Hits	108
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PZRN3_HUMAN
NC score	0.118612 (rank : 188)	θ value	0.00869519 (rank : 143)
Query Neighborhood Hits	258	Target Neighborhood Hits	461	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ZO2_MOUSE
NC score	0.118366 (rank : 189)	θ value	0.125558 (rank : 178)
Query Neighborhood Hits	258	Target Neighborhood Hits	296	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PZRN3_MOUSE
NC score	0.117715 (rank : 190)	θ value	0.0148317 (rank : 146)
Query Neighborhood Hits	258	Target Neighborhood Hits	447	Shared Neighborhood Hits	95
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

CC14B_MOUSE
NC score	0.116637 (rank : 191)	θ value	1.38821 (rank : 210)
Query Neighborhood Hits	258	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

LNX1_HUMAN
NC score	0.115334 (rank : 192)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	258	Target Neighborhood Hits	379	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

CC14B_HUMAN
NC score	0.114064 (rank : 193)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	258	Target Neighborhood Hits	114	Shared Neighborhood Hits	73
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

ZO1_MOUSE
NC score	0.112764 (rank : 194)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	258	Target Neighborhood Hits	453	Shared Neighborhood Hits	112
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_HUMAN
NC score	0.112273 (rank : 195)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	258	Target Neighborhood Hits	474	Shared Neighborhood Hits	114
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

FINC_HUMAN
NC score	0.111756 (rank : 196)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	258	Target Neighborhood Hits	302	Shared Neighborhood Hits	26
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.110686 (rank : 197)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	258	Target Neighborhood Hits	309	Shared Neighborhood Hits	25
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

LDB3_MOUSE
NC score	0.105526 (rank : 198)	θ value	4.1701e-05 (rank : 118)
Query Neighborhood Hits	258	Target Neighborhood Hits	510	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LAP4_MOUSE
NC score	0.105176 (rank : 199)	θ value	0.0148317 (rank : 145)
Query Neighborhood Hits	258	Target Neighborhood Hits	590	Shared Neighborhood Hits	118
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

TP4A1_HUMAN
NC score	0.103964 (rank : 200)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	258	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.103964 (rank : 201)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	258	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

LDB3_HUMAN
NC score	0.103761 (rank : 202)	θ value	4.1701e-05 (rank : 117)
Query Neighborhood Hits	258	Target Neighborhood Hits	497	Shared Neighborhood Hits	100
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LAP4_HUMAN
NC score	0.103712 (rank : 203)	θ value	0.21417 (rank : 188)
Query Neighborhood Hits	258	Target Neighborhood Hits	608	Shared Neighborhood Hits	118
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

CC14A_MOUSE
NC score	0.101321 (rank : 204)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	258	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

FNDC3_HUMAN
NC score	0.099518 (rank : 205)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	258	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

CC14A_HUMAN
NC score	0.098395 (rank : 206)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	258	Target Neighborhood Hits	133	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

ARHGB_HUMAN
NC score	0.094714 (rank : 207)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	258	Target Neighborhood Hits	375	Shared Neighborhood Hits	115
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

RPGF6_HUMAN
NC score	0.093359 (rank : 208)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	258	Target Neighborhood Hits	266	Shared Neighborhood Hits	113
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PSCBP_MOUSE
NC score	0.093062 (rank : 209)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	258	Target Neighborhood Hits	118	Shared Neighborhood Hits	97
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

FNDC3_MOUSE
NC score	0.093012 (rank : 210)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	258	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

K1849_MOUSE
NC score	0.092854 (rank : 211)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	258	Target Neighborhood Hits	335	Shared Neighborhood Hits	94
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_HUMAN
NC score	0.090921 (rank : 212)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	258	Target Neighborhood Hits	220	Shared Neighborhood Hits	89
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

TP4A2_HUMAN
NC score	0.089608 (rank : 213)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	258	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.089608 (rank : 214)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	258	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

AFAD_HUMAN
NC score	0.087210 (rank : 215)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	258	Target Neighborhood Hits	689	Shared Neighborhood Hits	97
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

SDCB1_MOUSE
NC score	0.086827 (rank : 216)	θ value	0.813845 (rank : 205)
Query Neighborhood Hits	258	Target Neighborhood Hits	144	Shared Neighborhood Hits	95
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

ARHGC_HUMAN
NC score	0.086510 (rank : 217)	θ value	0.62314 (rank : 199)
Query Neighborhood Hits	258	Target Neighborhood Hits	351	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PSCBP_HUMAN
NC score	0.085437 (rank : 218)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	258	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

ARHGC_MOUSE
NC score	0.085399 (rank : 219)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	258	Target Neighborhood Hits	344	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

TP4A3_HUMAN
NC score	0.084669 (rank : 220)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	258	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

STXB4_HUMAN
NC score	0.084199 (rank : 221)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	258	Target Neighborhood Hits	616	Shared Neighborhood Hits	75
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

CDKN3_HUMAN
NC score	0.083889 (rank : 222)	θ value	0.21417 (rank : 183)
Query Neighborhood Hits	258	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

SDCB1_HUMAN
NC score	0.083325 (rank : 223)	θ value	0.813845 (rank : 204)
Query Neighborhood Hits	258	Target Neighborhood Hits	150	Shared Neighborhood Hits	96
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

PDLI7_HUMAN
NC score	0.082894 (rank : 224)	θ value	0.125558 (rank : 173)
Query Neighborhood Hits	258	Target Neighborhood Hits	547	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDLI7_MOUSE
NC score	0.082807 (rank : 225)	θ value	0.163984 (rank : 181)
Query Neighborhood Hits	258	Target Neighborhood Hits	279	Shared Neighborhood Hits	84
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDLI5_MOUSE
NC score	0.082686 (rank : 226)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	258	Target Neighborhood Hits	287	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

DCC_HUMAN
NC score	0.082254 (rank : 227)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	258	Target Neighborhood Hits	583	Shared Neighborhood Hits	32
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

PDLI5_HUMAN
NC score	0.080486 (rank : 228)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	258	Target Neighborhood Hits	322	Shared Neighborhood Hits	96
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

NEO1_MOUSE
NC score	0.080284 (rank : 229)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	258	Target Neighborhood Hits	523	Shared Neighborhood Hits	29
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

DCC_MOUSE
NC score	0.080033 (rank : 230)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	258	Target Neighborhood Hits	896	Shared Neighborhood Hits	38
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

RGS12_HUMAN
NC score	0.079204 (rank : 231)	θ value	0.47712 (rank : 197)
Query Neighborhood Hits	258	Target Neighborhood Hits	333	Shared Neighborhood Hits	103
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

NEO1_HUMAN
NC score	0.077545 (rank : 232)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	258	Target Neighborhood Hits	530	Shared Neighborhood Hits	28
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

DLG5_HUMAN
NC score	0.077207 (rank : 233)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	258	Target Neighborhood Hits	1088	Shared Neighborhood Hits	113
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PICK1_HUMAN
NC score	0.076757 (rank : 234)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	258	Target Neighborhood Hits	132	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

TENN_MOUSE
NC score	0.076421 (rank : 235)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	258	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

SDCB2_HUMAN
NC score	0.075914 (rank : 236)	θ value	0.813845 (rank : 206)
Query Neighborhood Hits	258	Target Neighborhood Hits	121	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

NEB2_HUMAN
NC score	0.075626 (rank : 237)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	258	Target Neighborhood Hits	883	Shared Neighborhood Hits	77
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PICK1_MOUSE
NC score	0.075270 (rank : 238)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	258	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

STXB4_MOUSE
NC score	0.074976 (rank : 239)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	258	Target Neighborhood Hits	629	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PDZK4_MOUSE
NC score	0.074811 (rank : 240)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	258	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

TP4A3_MOUSE
NC score	0.074482 (rank : 241)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

PTEN_HUMAN
NC score	0.074460 (rank : 242)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	258	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.074459 (rank : 243)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	258	Target Neighborhood Hits	73	Shared Neighborhood Hits	42
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

MAMC2_MOUSE
NC score	0.074250 (rank : 244)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	258	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NEB1_HUMAN
NC score	0.073541 (rank : 245)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	258	Target Neighborhood Hits	829	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

COCA1_MOUSE
NC score	0.073426 (rank : 246)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	258	Target Neighborhood Hits	467	Shared Neighborhood Hits	24
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

PDZK4_HUMAN
NC score	0.073361 (rank : 247)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	258	Target Neighborhood Hits	165	Shared Neighborhood Hits	78
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

NEB2_MOUSE
NC score	0.073290 (rank : 248)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	258	Target Neighborhood Hits	889	Shared Neighborhood Hits	78
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

COCA1_HUMAN
NC score	0.071596 (rank : 249)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	258	Target Neighborhood Hits	458	Shared Neighborhood Hits	28
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

USH2A_HUMAN
NC score	0.071375 (rank : 250)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	258	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

MAMC2_HUMAN
NC score	0.071204 (rank : 251)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	258	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

RPGF2_HUMAN
NC score	0.071050 (rank : 252)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	258	Target Neighborhood Hits	242	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SDK2_MOUSE
NC score	0.069414 (rank : 253)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	258	Target Neighborhood Hits	480	Shared Neighborhood Hits	26
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDCB2_MOUSE
NC score	0.069204 (rank : 254)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	258	Target Neighborhood Hits	118	Shared Neighborhood Hits	79
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

MPP4_HUMAN
NC score	0.068873 (rank : 255)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	258	Target Neighborhood Hits	205	Shared Neighborhood Hits	82
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

USH2A_MOUSE
NC score	0.068371 (rank : 256)	θ value	2.36792 (rank : 226)
Query Neighborhood Hits	258	Target Neighborhood Hits	626	Shared Neighborhood Hits	22
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

KRIT1_HUMAN
NC score	0.068285 (rank : 257)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	258	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

SDK1_MOUSE
NC score	0.066803 (rank : 258)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	258	Target Neighborhood Hits	495	Shared Neighborhood Hits	26
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
NC score	0.066671 (rank : 259)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	258	Target Neighborhood Hits	495	Shared Neighborhood Hits	26
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NOS1_HUMAN
NC score	0.066296 (rank : 260)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	258	Target Neighborhood Hits	218	Shared Neighborhood Hits	87
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SDK1_HUMAN
NC score	0.065840 (rank : 261)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	258	Target Neighborhood Hits	511	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TENN_HUMAN
NC score	0.065249 (rank : 262)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	258	Target Neighborhood Hits	453	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

RHPN2_MOUSE
NC score	0.064688 (rank : 263)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

KRIT1_MOUSE
NC score	0.064194 (rank : 264)	θ value	3.0926 (rank : 228)
Query Neighborhood Hits	258	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

TENR_HUMAN
NC score	0.064090 (rank : 265)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	258	Target Neighborhood Hits	526	Shared Neighborhood Hits	21
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
NC score	0.063891 (rank : 266)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	258	Target Neighborhood Hits	531	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

PAR6G_MOUSE
NC score	0.063547 (rank : 267)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	258	Target Neighborhood Hits	121	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PAR6G_HUMAN
NC score	0.063535 (rank : 268)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	258	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

LRRC7_HUMAN
NC score	0.063514 (rank : 269)	θ value	0.0961366 (rank : 167)
Query Neighborhood Hits	258	Target Neighborhood Hits	423	Shared Neighborhood Hits	96
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.062974 (rank : 270)	θ value	0.0961366 (rank : 168)
Query Neighborhood Hits	258	Target Neighborhood Hits	416	Shared Neighborhood Hits	95
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

ITB4_HUMAN
NC score	0.062846 (rank : 271)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	258	Target Neighborhood Hits	458	Shared Neighborhood Hits	20
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

APBA1_HUMAN
NC score	0.062563 (rank : 272)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	258	Target Neighborhood Hits	325	Shared Neighborhood Hits	85
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PAR6B_HUMAN
NC score	0.061427 (rank : 273)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	258	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

DVL1_HUMAN
NC score	0.061167 (rank : 274)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	258	Target Neighborhood Hits	158	Shared Neighborhood Hits	75
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

PAR6B_MOUSE
NC score	0.061042 (rank : 275)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	258	Target Neighborhood Hits	128	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

L1CAM_MOUSE
NC score	0.060894 (rank : 276)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	258	Target Neighborhood Hits	457	Shared Neighborhood Hits	26
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

MPP5_MOUSE
NC score	0.060765 (rank : 277)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	258	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

DVL3_HUMAN
NC score	0.060755 (rank : 278)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	258	Target Neighborhood Hits	194	Shared Neighborhood Hits	71
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

MPP5_HUMAN
NC score	0.060729 (rank : 279)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	258	Target Neighborhood Hits	231	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

DVL3_MOUSE
NC score	0.060236 (rank : 280)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	258	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

L1CAM_HUMAN
NC score	0.059993 (rank : 281)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	258	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

COEA1_MOUSE
NC score	0.059805 (rank : 282)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	258	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

MPP3_MOUSE
NC score	0.059782 (rank : 283)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	258	Target Neighborhood Hits	165	Shared Neighborhood Hits	75
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

NRCAM_MOUSE
NC score	0.059747 (rank : 284)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	258	Target Neighborhood Hits	432	Shared Neighborhood Hits	21
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

DSCAM_HUMAN
NC score	0.059674 (rank : 285)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	258	Target Neighborhood Hits	524	Shared Neighborhood Hits	23
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

CA106_HUMAN
NC score	0.059669 (rank : 286)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	258	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

DVL1_MOUSE
NC score	0.059641 (rank : 287)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	258	Target Neighborhood Hits	146	Shared Neighborhood Hits	73
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DSCL1_HUMAN
NC score	0.059520 (rank : 288)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	258	Target Neighborhood Hits	589	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

APBA2_HUMAN
NC score	0.059360 (rank : 289)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	258	Target Neighborhood Hits	220	Shared Neighborhood Hits	81
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
NC score	0.059091 (rank : 290)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	258	Target Neighborhood Hits	201	Shared Neighborhood Hits	75
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

LAP2_HUMAN
NC score	0.058961 (rank : 291)	θ value	0.00390308 (rank : 141)
Query Neighborhood Hits	258	Target Neighborhood Hits	499	Shared Neighborhood Hits	87
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

CA106_MOUSE
NC score	0.058856 (rank : 292)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	258	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

MPP3_HUMAN
NC score	0.058855 (rank : 293)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	258	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

APBA2_MOUSE
NC score	0.058564 (rank : 294)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	258	Target Neighborhood Hits	219	Shared Neighborhood Hits	81
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

NRCAM_HUMAN
NC score	0.057866 (rank : 295)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	258	Target Neighborhood Hits	439	Shared Neighborhood Hits	19
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

APBA3_MOUSE
NC score	0.057850 (rank : 296)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	258	Target Neighborhood Hits	174	Shared Neighborhood Hits	76
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

TARSH_HUMAN
NC score	0.057824 (rank : 297)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	258	Target Neighborhood Hits	768	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CNTN5_HUMAN
NC score	0.057768 (rank : 298)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	258	Target Neighborhood Hits	446	Shared Neighborhood Hits	21
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

MPP4_MOUSE
NC score	0.057432 (rank : 299)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	258	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

DVL2_HUMAN
NC score	0.057425 (rank : 300)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	258	Target Neighborhood Hits	223	Shared Neighborhood Hits	72
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.057407 (rank : 301)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	258	Target Neighborhood Hits	233	Shared Neighborhood Hits	72
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

RES18_MOUSE
NC score	0.057291 (rank : 302)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	258	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

NOS1_MOUSE
NC score	0.057069 (rank : 303)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	258	Target Neighborhood Hits	155	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

DVL1L_HUMAN
NC score	0.056826 (rank : 304)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	258	Target Neighborhood Hits	146	Shared Neighborhood Hits	74
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

CO7A1_HUMAN
NC score	0.056590 (rank : 305)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	258	Target Neighborhood Hits	807	Shared Neighborhood Hits	26
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MDGA1_HUMAN
NC score	0.056468 (rank : 306)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	258	Target Neighborhood Hits	358	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

CNTN5_MOUSE
NC score	0.056459 (rank : 307)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	258	Target Neighborhood Hits	434	Shared Neighborhood Hits	20
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

LAP2_MOUSE
NC score	0.056180 (rank : 308)	θ value	0.0113563 (rank : 144)
Query Neighborhood Hits	258	Target Neighborhood Hits	482	Shared Neighborhood Hits	86
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

CNTN2_HUMAN
NC score	0.056018 (rank : 309)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	258	Target Neighborhood Hits	440	Shared Neighborhood Hits	19
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
NC score	0.055826 (rank : 310)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	258	Target Neighborhood Hits	450	Shared Neighborhood Hits	19
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

TENA_HUMAN
NC score	0.055527 (rank : 311)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	258	Target Neighborhood Hits	631	Shared Neighborhood Hits	22
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

PDC6I_MOUSE
NC score	0.054364 (rank : 312)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	258	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PAR6A_MOUSE
NC score	0.054235 (rank : 313)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	258	Target Neighborhood Hits	115	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

MAMC1_MOUSE
NC score	0.053924 (rank : 314)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	258	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MYOM1_MOUSE
NC score	0.053800 (rank : 315)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	258	Target Neighborhood Hits	415	Shared Neighborhood Hits	22
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

PAR6A_HUMAN
NC score	0.053627 (rank : 316)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	258	Target Neighborhood Hits	119	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

RHPN2_HUMAN
NC score	0.053300 (rank : 317)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	258	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

SHAN2_HUMAN
NC score	0.053167 (rank : 318)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	258	Target Neighborhood Hits	346	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

COEA1_HUMAN
NC score	0.053148 (rank : 319)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	258	Target Neighborhood Hits	427	Shared Neighborhood Hits	21
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CNTN1_MOUSE
NC score	0.053052 (rank : 320)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	258	Target Neighborhood Hits	422	Shared Neighborhood Hits	18
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

MAMC1_HUMAN
NC score	0.052954 (rank : 321)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	258	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

NFASC_HUMAN
NC score	0.052261 (rank : 322)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	258	Target Neighborhood Hits	497	Shared Neighborhood Hits	20
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

CNTN1_HUMAN
NC score	0.051937 (rank : 323)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	258	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

PDC6I_HUMAN
NC score	0.051625 (rank : 324)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	258	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

EM55_HUMAN
NC score	0.051260 (rank : 325)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	258	Target Neighborhood Hits	228	Shared Neighborhood Hits	74
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

CNTN3_MOUSE
NC score	0.051199 (rank : 326)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	258	Target Neighborhood Hits	447	Shared Neighborhood Hits	22
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN6_HUMAN
NC score	0.050352 (rank : 327)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	258	Target Neighborhood Hits	422	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

MYOM1_HUMAN
NC score	0.050200 (rank : 328)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	258	Target Neighborhood Hits	405	Shared Neighborhood Hits	16
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NFASC_MOUSE
NC score	0.050106 (rank : 329)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	258	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

DUS2_MOUSE
NC score	0.049656 (rank : 330)	θ value	0.813845 (rank : 201)
Query Neighborhood Hits	258	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS5_HUMAN
NC score	0.048744 (rank : 331)	θ value	0.0193708 (rank : 150)
Query Neighborhood Hits	258	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS4_MOUSE
NC score	0.043463 (rank : 332)	θ value	0.0563607 (rank : 165)
Query Neighborhood Hits	258	Target Neighborhood Hits	75	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS4_HUMAN
NC score	0.043298 (rank : 333)	θ value	0.0563607 (rank : 164)
Query Neighborhood Hits	258	Target Neighborhood Hits	77	Shared Neighborhood Hits	31
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS1_HUMAN
NC score	0.039923 (rank : 334)	θ value	0.21417 (rank : 184)
Query Neighborhood Hits	258	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS1_MOUSE
NC score	0.039148 (rank : 335)	θ value	0.21417 (rank : 185)
Query Neighborhood Hits	258	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS13_HUMAN
NC score	0.038927 (rank : 336)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	258	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

DUS13_MOUSE
NC score	0.033937 (rank : 337)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	258	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

SHAN1_HUMAN
NC score	0.033532 (rank : 338)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	258	Target Neighborhood Hits	1041	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

DUS15_HUMAN
NC score	0.027453 (rank : 339)	θ value	0.813845 (rank : 200)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS7_HUMAN
NC score	0.027423 (rank : 340)	θ value	1.38821 (rank : 214)
Query Neighborhood Hits	258	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS6_MOUSE
NC score	0.026946 (rank : 341)	θ value	1.38821 (rank : 213)
Query Neighborhood Hits	258	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS6_HUMAN
NC score	0.026934 (rank : 342)	θ value	1.38821 (rank : 212)
Query Neighborhood Hits	258	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

MY18A_MOUSE
NC score	0.026067 (rank : 343)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	258	Target Neighborhood Hits	1989	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

DUS22_MOUSE
NC score	0.025707 (rank : 344)	θ value	1.38821 (rank : 211)
Query Neighborhood Hits	258	Target Neighborhood Hits	57	Shared Neighborhood Hits	23
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

MY18A_HUMAN
NC score	0.025555 (rank : 345)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	258	Target Neighborhood Hits	1929	Shared Neighborhood Hits	94
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

DUS22_HUMAN
NC score	0.024677 (rank : 346)	θ value	3.0926 (rank : 227)
Query Neighborhood Hits	258	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS19_MOUSE
NC score	0.024365 (rank : 347)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	258	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS11_HUMAN
NC score	0.021956 (rank : 348)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	258	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

VPS54_MOUSE
NC score	0.021849 (rank : 349)	θ value	0.0961366 (rank : 170)
Query Neighborhood Hits	258	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

DUS12_HUMAN
NC score	0.020545 (rank : 350)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	258	Target Neighborhood Hits	60	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

MLL3_MOUSE
NC score	0.017672 (rank : 351)	θ value	1.81305 (rank : 218)
Query Neighborhood Hits	258	Target Neighborhood Hits	1399	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

LRFN3_HUMAN
NC score	0.012011 (rank : 352)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	258	Target Neighborhood Hits	444	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
NC score	0.011871 (rank : 353)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	258	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

UNC5C_HUMAN
NC score	0.011581 (rank : 354)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	258	Target Neighborhood Hits	226	Shared Neighborhood Hits	8
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

ENAM_HUMAN
NC score	0.008991 (rank : 355)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	258	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

CING_HUMAN
NC score	0.007757 (rank : 356)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	258	Target Neighborhood Hits	1275	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

APC_HUMAN
NC score	0.005991 (rank : 357)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	258	Target Neighborhood Hits	603	Shared Neighborhood Hits	12
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
NC score	0.004747 (rank : 358)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	258	Target Neighborhood Hits	441	Shared Neighborhood Hits	13
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ARMX5_HUMAN
NC score	0.003246 (rank : 359)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	258	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1M9, Q68DB4, Q9BVZ3, Q9H969	Gene names	ARMCX5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

NF2L2_HUMAN
NC score	0.002174 (rank : 360)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	258	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

TBX20_MOUSE
NC score	0.001873 (rank : 361)	θ value	1.81305 (rank : 220)
Query Neighborhood Hits	258	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

PDE8A_MOUSE
NC score	0.001724 (rank : 362)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	258	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O88502	Gene names	Pde8a, Pde8
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17) (MMPDE8).

PAX7_HUMAN
NC score	-0.003383 (rank : 363)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	258	Target Neighborhood Hits	456	Shared Neighborhood Hits	5
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

PAX7_MOUSE
NC score	-0.003435 (rank : 364)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	258	Target Neighborhood Hits	422	Shared Neighborhood Hits	4
SwissProt Accessions	P47239, Q9ES16	Gene names	Pax7, Pax-7
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-7.