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Network neighborhood for query Sequence : PTN13_MOUSE

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PTN13_MOUSE
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTN13_HUMAN
θ value	0 (rank : 1)	NC score	0.990296 (rank : 2)
Query Neighborhood Hits	426	Target Neighborhood Hits	471	Shared Neighborhood Hits	314
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	426	Target Neighborhood Hits	426	Shared Neighborhood Hits	426
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN3_HUMAN
θ value	2.1121e-49 (rank : 3)	NC score	0.875964 (rank : 3)
Query Neighborhood Hits	426	Target Neighborhood Hits	258	Shared Neighborhood Hits	219
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN6_MOUSE
θ value	2.58187e-47 (rank : 4)	NC score	0.684021 (rank : 42)
Query Neighborhood Hits	426	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN4_HUMAN
θ value	9.81109e-47 (rank : 5)	NC score	0.871849 (rank : 4)
Query Neighborhood Hits	426	Target Neighborhood Hits	303	Shared Neighborhood Hits	228
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN6_HUMAN
θ value	1.67352e-46 (rank : 6)	NC score	0.685810 (rank : 40)
Query Neighborhood Hits	426	Target Neighborhood Hits	234	Shared Neighborhood Hits	72
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTPRF_HUMAN
θ value	1.41672e-45 (rank : 7)	NC score	0.502882 (rank : 60)
Query Neighborhood Hits	426	Target Neighborhood Hits	489	Shared Neighborhood Hits	75
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTN11_HUMAN
θ value	2.41655e-45 (rank : 8)	NC score	0.667848 (rank : 44)
Query Neighborhood Hits	426	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	2.41655e-45 (rank : 9)	NC score	0.667860 (rank : 43)
Query Neighborhood Hits	426	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTPRB_HUMAN
θ value	2.41655e-45 (rank : 10)	NC score	0.666562 (rank : 45)
Query Neighborhood Hits	426	Target Neighborhood Hits	242	Shared Neighborhood Hits	75
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTN21_MOUSE
θ value	4.122e-45 (rank : 11)	NC score	0.814867 (rank : 5)
Query Neighborhood Hits	426	Target Neighborhood Hits	155	Shared Neighborhood Hits	107
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN14_HUMAN
θ value	3.48949e-44 (rank : 12)	NC score	0.814564 (rank : 8)
Query Neighborhood Hits	426	Target Neighborhood Hits	163	Shared Neighborhood Hits	116
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN21_HUMAN
θ value	3.48949e-44 (rank : 13)	NC score	0.814652 (rank : 6)
Query Neighborhood Hits	426	Target Neighborhood Hits	143	Shared Neighborhood Hits	106
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTPRD_HUMAN
θ value	3.48949e-44 (rank : 14)	NC score	0.505158 (rank : 59)
Query Neighborhood Hits	426	Target Neighborhood Hits	485	Shared Neighborhood Hits	77
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRS_HUMAN
θ value	4.55743e-44 (rank : 15)	NC score	0.514796 (rank : 58)
Query Neighborhood Hits	426	Target Neighborhood Hits	472	Shared Neighborhood Hits	77
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTN14_MOUSE
θ value	1.32601e-43 (rank : 16)	NC score	0.814627 (rank : 7)
Query Neighborhood Hits	426	Target Neighborhood Hits	142	Shared Neighborhood Hits	110
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN2_MOUSE
θ value	1.46607e-42 (rank : 17)	NC score	0.727314 (rank : 9)
Query Neighborhood Hits	426	Target Neighborhood Hits	107	Shared Neighborhood Hits	66
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTPRK_MOUSE
θ value	1.46607e-42 (rank : 18)	NC score	0.660582 (rank : 47)
Query Neighborhood Hits	426	Target Neighborhood Hits	223	Shared Neighborhood Hits	68
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRJ_HUMAN
θ value	2.50074e-42 (rank : 19)	NC score	0.690468 (rank : 39)
Query Neighborhood Hits	426	Target Neighborhood Hits	207	Shared Neighborhood Hits	77
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRT_HUMAN
θ value	2.50074e-42 (rank : 20)	NC score	0.657205 (rank : 48)
Query Neighborhood Hits	426	Target Neighborhood Hits	217	Shared Neighborhood Hits	70
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	2.50074e-42 (rank : 21)	NC score	0.657174 (rank : 49)
Query Neighborhood Hits	426	Target Neighborhood Hits	219	Shared Neighborhood Hits	68
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRJ_MOUSE
θ value	3.26607e-42 (rank : 22)	NC score	0.693577 (rank : 38)
Query Neighborhood Hits	426	Target Neighborhood Hits	188	Shared Neighborhood Hits	74
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	4.2656e-42 (rank : 23)	NC score	0.661885 (rank : 46)
Query Neighborhood Hits	426	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN2_HUMAN
θ value	1.62093e-41 (rank : 24)	NC score	0.726727 (rank : 11)
Query Neighborhood Hits	426	Target Neighborhood Hits	92	Shared Neighborhood Hits	66
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTPRM_HUMAN
θ value	2.76489e-41 (rank : 25)	NC score	0.645025 (rank : 52)
Query Neighborhood Hits	426	Target Neighborhood Hits	244	Shared Neighborhood Hits	71
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	6.15952e-41 (rank : 26)	NC score	0.646422 (rank : 51)
Query Neighborhood Hits	426	Target Neighborhood Hits	238	Shared Neighborhood Hits	71
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTN12_HUMAN
θ value	1.79215e-40 (rank : 27)	NC score	0.719634 (rank : 17)
Query Neighborhood Hits	426	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTPRD_MOUSE
θ value	1.79215e-40 (rank : 28)	NC score	0.496588 (rank : 63)
Query Neighborhood Hits	426	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRA_HUMAN
θ value	5.21438e-40 (rank : 29)	NC score	0.706605 (rank : 33)
Query Neighborhood Hits	426	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTN12_MOUSE
θ value	6.81017e-40 (rank : 30)	NC score	0.718981 (rank : 18)
Query Neighborhood Hits	426	Target Neighborhood Hits	123	Shared Neighborhood Hits	70
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRE_HUMAN
θ value	6.81017e-40 (rank : 31)	NC score	0.707592 (rank : 31)
Query Neighborhood Hits	426	Target Neighborhood Hits	92	Shared Neighborhood Hits	71
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	6.81017e-40 (rank : 32)	NC score	0.707529 (rank : 32)
Query Neighborhood Hits	426	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTN1_HUMAN
θ value	2.58786e-39 (rank : 33)	NC score	0.726536 (rank : 12)
Query Neighborhood Hits	426	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	3.37985e-39 (rank : 34)	NC score	0.727006 (rank : 10)
Query Neighborhood Hits	426	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTPRO_HUMAN
θ value	4.41421e-39 (rank : 35)	NC score	0.713695 (rank : 22)
Query Neighborhood Hits	426	Target Neighborhood Hits	139	Shared Neighborhood Hits	72
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

CD45_HUMAN
θ value	5.76516e-39 (rank : 36)	NC score	0.703304 (rank : 37)
Query Neighborhood Hits	426	Target Neighborhood Hits	243	Shared Neighborhood Hits	73
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	5.76516e-39 (rank : 37)	NC score	0.708554 (rank : 29)
Query Neighborhood Hits	426	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTN7_MOUSE
θ value	9.83387e-39 (rank : 38)	NC score	0.724404 (rank : 14)
Query Neighborhood Hits	426	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTPRV_MOUSE
θ value	1.6774e-38 (rank : 39)	NC score	0.684185 (rank : 41)
Query Neighborhood Hits	426	Target Neighborhood Hits	179	Shared Neighborhood Hits	69
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN18_HUMAN
θ value	3.73686e-38 (rank : 40)	NC score	0.726132 (rank : 13)
Query Neighborhood Hits	426	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN7_HUMAN
θ value	1.42001e-37 (rank : 41)	NC score	0.723771 (rank : 15)
Query Neighborhood Hits	426	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN22_HUMAN
θ value	9.20422e-37 (rank : 42)	NC score	0.717737 (rank : 19)
Query Neighborhood Hits	426	Target Neighborhood Hits	109	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTPRN_MOUSE
θ value	4.568e-36 (rank : 43)	NC score	0.703825 (rank : 36)
Query Neighborhood Hits	426	Target Neighborhood Hits	240	Shared Neighborhood Hits	74
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTN22_MOUSE
θ value	1.01765e-35 (rank : 44)	NC score	0.713131 (rank : 24)
Query Neighborhood Hits	426	Target Neighborhood Hits	179	Shared Neighborhood Hits	76
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPRN_HUMAN
θ value	1.01765e-35 (rank : 45)	NC score	0.706422 (rank : 34)
Query Neighborhood Hits	426	Target Neighborhood Hits	156	Shared Neighborhood Hits	71
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPR2_MOUSE
θ value	1.73584e-35 (rank : 46)	NC score	0.708862 (rank : 27)
Query Neighborhood Hits	426	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTN18_MOUSE
θ value	2.26708e-35 (rank : 47)	NC score	0.723443 (rank : 16)
Query Neighborhood Hits	426	Target Neighborhood Hits	134	Shared Neighborhood Hits	75
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTPRA_MOUSE
θ value	2.26708e-35 (rank : 48)	NC score	0.704417 (rank : 35)
Query Neighborhood Hits	426	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRR_HUMAN
θ value	3.86705e-35 (rank : 49)	NC score	0.713190 (rank : 23)
Query Neighborhood Hits	426	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPR2_HUMAN
θ value	5.0505e-35 (rank : 50)	NC score	0.710114 (rank : 26)
Query Neighborhood Hits	426	Target Neighborhood Hits	103	Shared Neighborhood Hits	68
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTN9_HUMAN
θ value	8.61488e-35 (rank : 51)	NC score	0.708472 (rank : 30)
Query Neighborhood Hits	426	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRG_HUMAN
θ value	1.46948e-34 (rank : 52)	NC score	0.635329 (rank : 54)
Query Neighborhood Hits	426	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTN9_MOUSE
θ value	1.9192e-34 (rank : 53)	NC score	0.708597 (rank : 28)
Query Neighborhood Hits	426	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRZ_HUMAN
θ value	2.50655e-34 (rank : 54)	NC score	0.636306 (rank : 53)
Query Neighborhood Hits	426	Target Neighborhood Hits	255	Shared Neighborhood Hits	71
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

MERL_MOUSE
θ value	4.27553e-34 (rank : 55)	NC score	0.457779 (rank : 86)
Query Neighborhood Hits	426	Target Neighborhood Hits	524	Shared Neighborhood Hits	71
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
θ value	5.584e-34 (rank : 56)	NC score	0.458151 (rank : 85)
Query Neighborhood Hits	426	Target Neighborhood Hits	532	Shared Neighborhood Hits	72
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

PTPRG_MOUSE
θ value	2.77131e-33 (rank : 57)	NC score	0.633257 (rank : 55)
Query Neighborhood Hits	426	Target Neighborhood Hits	260	Shared Neighborhood Hits	75
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRR_MOUSE
θ value	2.77131e-33 (rank : 58)	NC score	0.711735 (rank : 25)
Query Neighborhood Hits	426	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRU_HUMAN
θ value	2.77131e-33 (rank : 59)	NC score	0.648405 (rank : 50)
Query Neighborhood Hits	426	Target Neighborhood Hits	237	Shared Neighborhood Hits	69
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTN23_HUMAN
θ value	8.91499e-32 (rank : 60)	NC score	0.624727 (rank : 57)
Query Neighborhood Hits	426	Target Neighborhood Hits	646	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN5_HUMAN
θ value	1.52067e-31 (rank : 61)	NC score	0.714081 (rank : 20)
Query Neighborhood Hits	426	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

RADI_HUMAN
θ value	3.3877e-31 (rank : 62)	NC score	0.422465 (rank : 112)
Query Neighborhood Hits	426	Target Neighborhood Hits	741	Shared Neighborhood Hits	73
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	3.3877e-31 (rank : 63)	NC score	0.419989 (rank : 115)
Query Neighborhood Hits	426	Target Neighborhood Hits	773	Shared Neighborhood Hits	74
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

PTN5_MOUSE
θ value	7.54701e-31 (rank : 64)	NC score	0.714035 (rank : 21)
Query Neighborhood Hits	426	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN23_MOUSE
θ value	2.19584e-30 (rank : 65)	NC score	0.626118 (rank : 56)
Query Neighborhood Hits	426	Target Neighborhood Hits	726	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

FRMD6_MOUSE
θ value	3.74554e-30 (rank : 66)	NC score	0.478517 (rank : 73)
Query Neighborhood Hits	426	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

MOES_MOUSE
θ value	1.85889e-29 (rank : 67)	NC score	0.391949 (rank : 138)
Query Neighborhood Hits	426	Target Neighborhood Hits	923	Shared Neighborhood Hits	82
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	2.42779e-29 (rank : 68)	NC score	0.396453 (rank : 135)
Query Neighborhood Hits	426	Target Neighborhood Hits	892	Shared Neighborhood Hits	79
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD1_HUMAN
θ value	9.2256e-29 (rank : 69)	NC score	0.476552 (rank : 76)
Query Neighborhood Hits	426	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

EZRI_HUMAN
θ value	2.05525e-28 (rank : 70)	NC score	0.429728 (rank : 102)
Query Neighborhood Hits	426	Target Neighborhood Hits	663	Shared Neighborhood Hits	74
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	2.68423e-28 (rank : 71)	NC score	0.428580 (rank : 104)
Query Neighborhood Hits	426	Target Neighborhood Hits	693	Shared Neighborhood Hits	75
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FRMD6_HUMAN
θ value	4.57862e-28 (rank : 72)	NC score	0.473438 (rank : 81)
Query Neighborhood Hits	426	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

E41LA_MOUSE
θ value	5.06226e-27 (rank : 73)	NC score	0.498791 (rank : 62)
Query Neighborhood Hits	426	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_HUMAN
θ value	8.63488e-27 (rank : 74)	NC score	0.498954 (rank : 61)
Query Neighborhood Hits	426	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

41_HUMAN
θ value	7.30988e-26 (rank : 75)	NC score	0.481100 (rank : 70)
Query Neighborhood Hits	426	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

MPDZ_HUMAN
θ value	7.30988e-26 (rank : 76)	NC score	0.475295 (rank : 78)
Query Neighborhood Hits	426	Target Neighborhood Hits	261	Shared Neighborhood Hits	191
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

E41L3_HUMAN
θ value	1.24688e-25 (rank : 77)	NC score	0.481767 (rank : 69)
Query Neighborhood Hits	426	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L3_MOUSE
θ value	2.12685e-25 (rank : 78)	NC score	0.473593 (rank : 80)
Query Neighborhood Hits	426	Target Neighborhood Hits	250	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

DLG2_MOUSE
θ value	6.18819e-25 (rank : 79)	NC score	0.425208 (rank : 107)
Query Neighborhood Hits	426	Target Neighborhood Hits	271	Shared Neighborhood Hits	177
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

E41L2_HUMAN
θ value	6.18819e-25 (rank : 80)	NC score	0.473839 (rank : 79)
Query Neighborhood Hits	426	Target Neighborhood Hits	287	Shared Neighborhood Hits	61
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MPDZ_MOUSE
θ value	6.18819e-25 (rank : 81)	NC score	0.476514 (rank : 77)
Query Neighborhood Hits	426	Target Neighborhood Hits	298	Shared Neighborhood Hits	193
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

E41L1_HUMAN
θ value	8.08199e-25 (rank : 82)	NC score	0.478903 (rank : 72)
Query Neighborhood Hits	426	Target Neighborhood Hits	180	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

INADL_HUMAN
θ value	1.05554e-24 (rank : 83)	NC score	0.470794 (rank : 83)
Query Neighborhood Hits	426	Target Neighborhood Hits	260	Shared Neighborhood Hits	190
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

E41L1_MOUSE
θ value	1.80048e-24 (rank : 84)	NC score	0.480860 (rank : 71)
Query Neighborhood Hits	426	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

INADL_MOUSE
θ value	1.80048e-24 (rank : 85)	NC score	0.473363 (rank : 82)
Query Neighborhood Hits	426	Target Neighborhood Hits	290	Shared Neighborhood Hits	194
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

DLG2_HUMAN
θ value	5.23862e-24 (rank : 86)	NC score	0.423828 (rank : 111)
Query Neighborhood Hits	426	Target Neighborhood Hits	279	Shared Neighborhood Hits	178
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

E41L2_MOUSE
θ value	5.23862e-24 (rank : 87)	NC score	0.459557 (rank : 84)
Query Neighborhood Hits	426	Target Neighborhood Hits	459	Shared Neighborhood Hits	77
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

41_MOUSE
θ value	1.99067e-23 (rank : 88)	NC score	0.477748 (rank : 75)
Query Neighborhood Hits	426	Target Neighborhood Hits	184	Shared Neighborhood Hits	56
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

FARP2_MOUSE
θ value	1.5773e-20 (rank : 89)	NC score	0.381305 (rank : 144)
Query Neighborhood Hits	426	Target Neighborhood Hits	209	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

E41LB_MOUSE
θ value	2.69047e-20 (rank : 90)	NC score	0.484088 (rank : 65)
Query Neighborhood Hits	426	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FRM4A_MOUSE
θ value	1.02238e-19 (rank : 91)	NC score	0.449995 (rank : 93)
Query Neighborhood Hits	426	Target Neighborhood Hits	108	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

E41L5_HUMAN
θ value	1.33526e-19 (rank : 92)	NC score	0.483267 (rank : 67)
Query Neighborhood Hits	426	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

FRM4A_HUMAN
θ value	1.74391e-19 (rank : 93)	NC score	0.450834 (rank : 89)
Query Neighborhood Hits	426	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

PARD3_MOUSE
θ value	3.88503e-19 (rank : 94)	NC score	0.442625 (rank : 99)
Query Neighborhood Hits	426	Target Neighborhood Hits	290	Shared Neighborhood Hits	171
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

E41LB_HUMAN
θ value	5.07402e-19 (rank : 95)	NC score	0.477845 (rank : 74)
Query Neighborhood Hits	426	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

DLG4_HUMAN
θ value	1.92812e-18 (rank : 96)	NC score	0.425923 (rank : 106)
Query Neighborhood Hits	426	Target Neighborhood Hits	286	Shared Neighborhood Hits	178
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

PARD3_HUMAN
θ value	1.92812e-18 (rank : 97)	NC score	0.444261 (rank : 98)
Query Neighborhood Hits	426	Target Neighborhood Hits	312	Shared Neighborhood Hits	171
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

DLG4_MOUSE
θ value	2.5182e-18 (rank : 98)	NC score	0.426600 (rank : 105)
Query Neighborhood Hits	426	Target Neighborhood Hits	282	Shared Neighborhood Hits	180
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG1_MOUSE
θ value	3.28887e-18 (rank : 99)	NC score	0.417327 (rank : 119)
Query Neighborhood Hits	426	Target Neighborhood Hits	285	Shared Neighborhood Hits	170
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG1_HUMAN
θ value	5.60996e-18 (rank : 100)	NC score	0.419003 (rank : 116)
Query Neighborhood Hits	426	Target Neighborhood Hits	290	Shared Neighborhood Hits	176
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG3_HUMAN
θ value	9.56915e-18 (rank : 101)	NC score	0.418772 (rank : 117)
Query Neighborhood Hits	426	Target Neighborhood Hits	269	Shared Neighborhood Hits	178
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

FRMD5_MOUSE
θ value	9.56915e-18 (rank : 102)	NC score	0.483429 (rank : 66)
Query Neighborhood Hits	426	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

DLG3_MOUSE
θ value	1.24977e-17 (rank : 103)	NC score	0.420233 (rank : 113)
Query Neighborhood Hits	426	Target Neighborhood Hits	274	Shared Neighborhood Hits	178
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

PDZD2_HUMAN
θ value	1.63225e-17 (rank : 104)	NC score	0.425031 (rank : 108)
Query Neighborhood Hits	426	Target Neighborhood Hits	772	Shared Neighborhood Hits	207
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

MAGI2_HUMAN
θ value	2.7842e-17 (rank : 105)	NC score	0.400184 (rank : 132)
Query Neighborhood Hits	426	Target Neighborhood Hits	373	Shared Neighborhood Hits	190
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

FRM4B_MOUSE
θ value	3.63628e-17 (rank : 106)	NC score	0.452163 (rank : 88)
Query Neighborhood Hits	426	Target Neighborhood Hits	109	Shared Neighborhood Hits	50
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FARP2_HUMAN
θ value	4.74913e-17 (rank : 107)	NC score	0.382729 (rank : 143)
Query Neighborhood Hits	426	Target Neighborhood Hits	240	Shared Neighborhood Hits	56
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MAGI2_MOUSE
θ value	6.20254e-17 (rank : 108)	NC score	0.402662 (rank : 130)
Query Neighborhood Hits	426	Target Neighborhood Hits	370	Shared Neighborhood Hits	197
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

FARP1_HUMAN
θ value	1.058e-16 (rank : 109)	NC score	0.394468 (rank : 137)
Query Neighborhood Hits	426	Target Neighborhood Hits	241	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FRM4B_HUMAN
θ value	1.058e-16 (rank : 110)	NC score	0.452752 (rank : 87)
Query Neighborhood Hits	426	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRMD5_HUMAN
θ value	1.058e-16 (rank : 111)	NC score	0.481841 (rank : 68)
Query Neighborhood Hits	426	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

MAGI1_MOUSE
θ value	1.058e-16 (rank : 112)	NC score	0.410271 (rank : 126)
Query Neighborhood Hits	426	Target Neighborhood Hits	403	Shared Neighborhood Hits	200
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

ZO1_MOUSE
θ value	3.07829e-16 (rank : 113)	NC score	0.360473 (rank : 154)
Query Neighborhood Hits	426	Target Neighborhood Hits	453	Shared Neighborhood Hits	173
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_HUMAN
θ value	4.02038e-16 (rank : 114)	NC score	0.356876 (rank : 159)
Query Neighborhood Hits	426	Target Neighborhood Hits	474	Shared Neighborhood Hits	174
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LAP4_HUMAN
θ value	6.85773e-16 (rank : 115)	NC score	0.295338 (rank : 174)
Query Neighborhood Hits	426	Target Neighborhood Hits	608	Shared Neighborhood Hits	196
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
θ value	1.16975e-15 (rank : 116)	NC score	0.294688 (rank : 175)
Query Neighborhood Hits	426	Target Neighborhood Hits	590	Shared Neighborhood Hits	195
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LNX2_MOUSE
θ value	7.58209e-15 (rank : 117)	NC score	0.413588 (rank : 125)
Query Neighborhood Hits	426	Target Neighborhood Hits	407	Shared Neighborhood Hits	180
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

GRIP1_MOUSE
θ value	2.20605e-14 (rank : 118)	NC score	0.415141 (rank : 122)
Query Neighborhood Hits	426	Target Neighborhood Hits	241	Shared Neighborhood Hits	190
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MAGI1_HUMAN
θ value	2.88119e-14 (rank : 119)	NC score	0.408211 (rank : 128)
Query Neighborhood Hits	426	Target Neighborhood Hits	388	Shared Neighborhood Hits	197
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PAR3L_HUMAN
θ value	1.86753e-13 (rank : 120)	NC score	0.447929 (rank : 95)
Query Neighborhood Hits	426	Target Neighborhood Hits	297	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

K1849_MOUSE
θ value	1.2105e-12 (rank : 121)	NC score	0.339095 (rank : 168)
Query Neighborhood Hits	426	Target Neighborhood Hits	335	Shared Neighborhood Hits	159
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

GRIP2_HUMAN
θ value	4.59992e-12 (rank : 122)	NC score	0.423987 (rank : 110)
Query Neighborhood Hits	426	Target Neighborhood Hits	256	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

K1849_HUMAN
θ value	4.59992e-12 (rank : 123)	NC score	0.347967 (rank : 164)
Query Neighborhood Hits	426	Target Neighborhood Hits	220	Shared Neighborhood Hits	144
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LNX1_MOUSE
θ value	4.59992e-12 (rank : 124)	NC score	0.401284 (rank : 131)
Query Neighborhood Hits	426	Target Neighborhood Hits	377	Shared Neighborhood Hits	180
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

GRIP1_HUMAN
θ value	1.74796e-11 (rank : 125)	NC score	0.414630 (rank : 123)
Query Neighborhood Hits	426	Target Neighborhood Hits	231	Shared Neighborhood Hits	194
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

LIN7A_HUMAN
θ value	2.28291e-11 (rank : 126)	NC score	0.446407 (rank : 96)
Query Neighborhood Hits	426	Target Neighborhood Hits	193	Shared Neighborhood Hits	181
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	2.28291e-11 (rank : 127)	NC score	0.446366 (rank : 97)
Query Neighborhood Hits	426	Target Neighborhood Hits	193	Shared Neighborhood Hits	181
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LNX1_HUMAN
θ value	2.28291e-11 (rank : 128)	NC score	0.395504 (rank : 136)
Query Neighborhood Hits	426	Target Neighborhood Hits	379	Shared Neighborhood Hits	172
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LIN7B_HUMAN
θ value	5.08577e-11 (rank : 129)	NC score	0.450059 (rank : 90)
Query Neighborhood Hits	426	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

SYJ2B_HUMAN
θ value	5.08577e-11 (rank : 130)	NC score	0.484702 (rank : 64)
Query Neighborhood Hits	426	Target Neighborhood Hits	162	Shared Neighborhood Hits	157
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

LIN7B_MOUSE
θ value	6.64225e-11 (rank : 131)	NC score	0.449016 (rank : 94)
Query Neighborhood Hits	426	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

MYLIP_MOUSE
θ value	6.64225e-11 (rank : 132)	NC score	0.442291 (rank : 100)
Query Neighborhood Hits	426	Target Neighborhood Hits	139	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

WHRN_MOUSE
θ value	8.67504e-11 (rank : 133)	NC score	0.416783 (rank : 121)
Query Neighborhood Hits	426	Target Neighborhood Hits	412	Shared Neighborhood Hits	190
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

LIN7C_HUMAN
θ value	1.133e-10 (rank : 134)	NC score	0.450025 (rank : 91)
Query Neighborhood Hits	426	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	1.133e-10 (rank : 135)	NC score	0.450025 (rank : 92)
Query Neighborhood Hits	426	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PDZD3_HUMAN
θ value	2.52405e-10 (rank : 136)	NC score	0.366865 (rank : 152)
Query Neighborhood Hits	426	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

NEB1_HUMAN
θ value	3.29651e-10 (rank : 137)	NC score	0.289213 (rank : 179)
Query Neighborhood Hits	426	Target Neighborhood Hits	829	Shared Neighborhood Hits	157
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

TLN1_HUMAN
θ value	3.29651e-10 (rank : 138)	NC score	0.255199 (rank : 194)
Query Neighborhood Hits	426	Target Neighborhood Hits	218	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

MYLIP_HUMAN
θ value	4.30538e-10 (rank : 139)	NC score	0.432051 (rank : 101)
Query Neighborhood Hits	426	Target Neighborhood Hits	162	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NOS1_HUMAN
θ value	4.30538e-10 (rank : 140)	NC score	0.216658 (rank : 224)
Query Neighborhood Hits	426	Target Neighborhood Hits	218	Shared Neighborhood Hits	142
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

LNX2_HUMAN
θ value	5.62301e-10 (rank : 141)	NC score	0.408199 (rank : 129)
Query Neighborhood Hits	426	Target Neighborhood Hits	389	Shared Neighborhood Hits	178
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TLN1_MOUSE
θ value	7.34386e-10 (rank : 142)	NC score	0.253647 (rank : 196)
Query Neighborhood Hits	426	Target Neighborhood Hits	213	Shared Neighborhood Hits	50
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

IL16_HUMAN
θ value	9.59137e-10 (rank : 143)	NC score	0.420002 (rank : 114)
Query Neighborhood Hits	426	Target Neighborhood Hits	207	Shared Neighborhood Hits	146
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

NHERF_MOUSE
θ value	9.59137e-10 (rank : 144)	NC score	0.389122 (rank : 140)
Query Neighborhood Hits	426	Target Neighborhood Hits	195	Shared Neighborhood Hits	159
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

WHRN_HUMAN
θ value	1.25267e-09 (rank : 145)	NC score	0.414598 (rank : 124)
Query Neighborhood Hits	426	Target Neighborhood Hits	325	Shared Neighborhood Hits	191
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

NOS1_MOUSE
θ value	3.64472e-09 (rank : 146)	NC score	0.193931 (rank : 231)
Query Neighborhood Hits	426	Target Neighborhood Hits	155	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PDZD1_HUMAN
θ value	3.64472e-09 (rank : 147)	NC score	0.391250 (rank : 139)
Query Neighborhood Hits	426	Target Neighborhood Hits	190	Shared Neighborhood Hits	153
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NEB2_HUMAN
θ value	4.76016e-09 (rank : 148)	NC score	0.279012 (rank : 184)
Query Neighborhood Hits	426	Target Neighborhood Hits	883	Shared Neighborhood Hits	147
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	4.76016e-09 (rank : 149)	NC score	0.274189 (rank : 185)
Query Neighborhood Hits	426	Target Neighborhood Hits	889	Shared Neighborhood Hits	150
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

IL16_MOUSE
θ value	6.21693e-09 (rank : 150)	NC score	0.408767 (rank : 127)
Query Neighborhood Hits	426	Target Neighborhood Hits	189	Shared Neighborhood Hits	142
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZD1_MOUSE
θ value	6.21693e-09 (rank : 151)	NC score	0.398529 (rank : 133)
Query Neighborhood Hits	426	Target Neighborhood Hits	191	Shared Neighborhood Hits	156
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

AFAD_HUMAN
θ value	8.11959e-09 (rank : 152)	NC score	0.304891 (rank : 173)
Query Neighborhood Hits	426	Target Neighborhood Hits	689	Shared Neighborhood Hits	156
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

USH1C_HUMAN
θ value	1.06045e-08 (rank : 153)	NC score	0.424932 (rank : 109)
Query Neighborhood Hits	426	Target Neighborhood Hits	327	Shared Neighborhood Hits	189
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

PZRN4_HUMAN
θ value	1.38499e-08 (rank : 154)	NC score	0.339943 (rank : 167)
Query Neighborhood Hits	426	Target Neighborhood Hits	438	Shared Neighborhood Hits	152
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZO2_HUMAN
θ value	1.80886e-08 (rank : 155)	NC score	0.358024 (rank : 158)
Query Neighborhood Hits	426	Target Neighborhood Hits	289	Shared Neighborhood Hits	179
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	1.80886e-08 (rank : 156)	NC score	0.356813 (rank : 160)
Query Neighborhood Hits	426	Target Neighborhood Hits	296	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

NHERF_HUMAN
θ value	2.36244e-08 (rank : 157)	NC score	0.374888 (rank : 150)
Query Neighborhood Hits	426	Target Neighborhood Hits	190	Shared Neighborhood Hits	156
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

USH1C_MOUSE
θ value	2.36244e-08 (rank : 158)	NC score	0.398453 (rank : 134)
Query Neighborhood Hits	426	Target Neighborhood Hits	557	Shared Neighborhood Hits	197
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ZO3_MOUSE
θ value	2.36244e-08 (rank : 159)	NC score	0.376935 (rank : 147)
Query Neighborhood Hits	426	Target Neighborhood Hits	224	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PZRN3_HUMAN
θ value	3.08544e-08 (rank : 160)	NC score	0.332110 (rank : 172)
Query Neighborhood Hits	426	Target Neighborhood Hits	461	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SNTG2_MOUSE
θ value	5.26297e-08 (rank : 161)	NC score	0.359843 (rank : 156)
Query Neighborhood Hits	426	Target Neighborhood Hits	176	Shared Neighborhood Hits	167
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PZRN3_MOUSE
θ value	6.87365e-08 (rank : 162)	NC score	0.332121 (rank : 171)
Query Neighborhood Hits	426	Target Neighborhood Hits	447	Shared Neighborhood Hits	153
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SNTG2_HUMAN
θ value	6.87365e-08 (rank : 163)	NC score	0.375378 (rank : 149)
Query Neighborhood Hits	426	Target Neighborhood Hits	191	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

TLN2_HUMAN
θ value	6.87365e-08 (rank : 164)	NC score	0.250974 (rank : 197)
Query Neighborhood Hits	426	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

GOPC_HUMAN
θ value	8.97725e-08 (rank : 165)	NC score	0.383270 (rank : 142)
Query Neighborhood Hits	426	Target Neighborhood Hits	377	Shared Neighborhood Hits	174
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	8.97725e-08 (rank : 166)	NC score	0.388497 (rank : 141)
Query Neighborhood Hits	426	Target Neighborhood Hits	323	Shared Neighborhood Hits	173
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

NHRF2_HUMAN
θ value	8.97725e-08 (rank : 167)	NC score	0.377036 (rank : 146)
Query Neighborhood Hits	426	Target Neighborhood Hits	197	Shared Neighborhood Hits	165
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

TLN2_MOUSE
θ value	1.17247e-07 (rank : 168)	NC score	0.254710 (rank : 195)
Query Neighborhood Hits	426	Target Neighborhood Hits	149	Shared Neighborhood Hits	57
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

PDZ11_MOUSE
θ value	1.53129e-07 (rank : 169)	NC score	0.418066 (rank : 118)
Query Neighborhood Hits	426	Target Neighborhood Hits	154	Shared Neighborhood Hits	137
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

ZO3_HUMAN
θ value	1.53129e-07 (rank : 170)	NC score	0.371842 (rank : 151)
Query Neighborhood Hits	426	Target Neighborhood Hits	219	Shared Neighborhood Hits	174
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

DLG5_HUMAN
θ value	2.61198e-07 (rank : 171)	NC score	0.262490 (rank : 192)
Query Neighborhood Hits	426	Target Neighborhood Hits	1088	Shared Neighborhood Hits	194
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

STXB4_HUMAN
θ value	2.61198e-07 (rank : 172)	NC score	0.266907 (rank : 188)
Query Neighborhood Hits	426	Target Neighborhood Hits	616	Shared Neighborhood Hits	120
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PDZ11_HUMAN
θ value	3.41135e-07 (rank : 173)	NC score	0.417065 (rank : 120)
Query Neighborhood Hits	426	Target Neighborhood Hits	160	Shared Neighborhood Hits	144
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZD7_HUMAN
θ value	3.41135e-07 (rank : 174)	NC score	0.428627 (rank : 103)
Query Neighborhood Hits	426	Target Neighborhood Hits	181	Shared Neighborhood Hits	168
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

SNTB2_MOUSE
θ value	4.45536e-07 (rank : 175)	NC score	0.360385 (rank : 155)
Query Neighborhood Hits	426	Target Neighborhood Hits	181	Shared Neighborhood Hits	160
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

DVL1_HUMAN
θ value	5.81887e-07 (rank : 176)	NC score	0.289271 (rank : 178)
Query Neighborhood Hits	426	Target Neighborhood Hits	158	Shared Neighborhood Hits	119
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GRASP_HUMAN
θ value	5.81887e-07 (rank : 177)	NC score	0.271260 (rank : 186)
Query Neighborhood Hits	426	Target Neighborhood Hits	147	Shared Neighborhood Hits	117
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

DVL1_MOUSE
θ value	7.59969e-07 (rank : 178)	NC score	0.287905 (rank : 180)
Query Neighborhood Hits	426	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

STXB4_MOUSE
θ value	9.92553e-07 (rank : 179)	NC score	0.256538 (rank : 193)
Query Neighborhood Hits	426	Target Neighborhood Hits	629	Shared Neighborhood Hits	113
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DVL3_HUMAN
θ value	1.29631e-06 (rank : 180)	NC score	0.290926 (rank : 176)
Query Neighborhood Hits	426	Target Neighborhood Hits	194	Shared Neighborhood Hits	116
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	1.29631e-06 (rank : 181)	NC score	0.290366 (rank : 177)
Query Neighborhood Hits	426	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

SNTB2_HUMAN
θ value	1.29631e-06 (rank : 182)	NC score	0.358936 (rank : 157)
Query Neighborhood Hits	426	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

DVL1L_HUMAN
θ value	1.69304e-06 (rank : 183)	NC score	0.279699 (rank : 181)
Query Neighborhood Hits	426	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

GRASP_MOUSE
θ value	1.69304e-06 (rank : 184)	NC score	0.267541 (rank : 187)
Query Neighborhood Hits	426	Target Neighborhood Hits	131	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

RIMS2_HUMAN
θ value	2.21117e-06 (rank : 185)	NC score	0.150115 (rank : 249)
Query Neighborhood Hits	426	Target Neighborhood Hits	342	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	2.21117e-06 (rank : 186)	NC score	0.149683 (rank : 250)
Query Neighborhood Hits	426	Target Neighborhood Hits	376	Shared Neighborhood Hits	114
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SNTG1_MOUSE
θ value	2.88788e-06 (rank : 187)	NC score	0.349833 (rank : 162)
Query Neighborhood Hits	426	Target Neighborhood Hits	179	Shared Neighborhood Hits	171
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDZD3_MOUSE
θ value	3.77169e-06 (rank : 188)	NC score	0.342309 (rank : 166)
Query Neighborhood Hits	426	Target Neighborhood Hits	171	Shared Neighborhood Hits	155
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SNTG1_HUMAN
θ value	3.77169e-06 (rank : 189)	NC score	0.349033 (rank : 163)
Query Neighborhood Hits	426	Target Neighborhood Hits	181	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

DVL2_HUMAN
θ value	4.92598e-06 (rank : 190)	NC score	0.279687 (rank : 182)
Query Neighborhood Hits	426	Target Neighborhood Hits	223	Shared Neighborhood Hits	117
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	4.92598e-06 (rank : 191)	NC score	0.279514 (rank : 183)
Query Neighborhood Hits	426	Target Neighborhood Hits	233	Shared Neighborhood Hits	119
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

LRRC7_HUMAN
θ value	4.92598e-06 (rank : 192)	NC score	0.160864 (rank : 245)
Query Neighborhood Hits	426	Target Neighborhood Hits	423	Shared Neighborhood Hits	115
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	4.92598e-06 (rank : 193)	NC score	0.160054 (rank : 246)
Query Neighborhood Hits	426	Target Neighborhood Hits	416	Shared Neighborhood Hits	115
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

SNTA1_HUMAN
θ value	6.43352e-06 (rank : 194)	NC score	0.350044 (rank : 161)
Query Neighborhood Hits	426	Target Neighborhood Hits	186	Shared Neighborhood Hits	165
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

LAP2_HUMAN
θ value	8.40245e-06 (rank : 195)	NC score	0.151635 (rank : 248)
Query Neighborhood Hits	426	Target Neighborhood Hits	499	Shared Neighborhood Hits	112
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SNTA1_MOUSE
θ value	1.09739e-05 (rank : 196)	NC score	0.344997 (rank : 165)
Query Neighborhood Hits	426	Target Neighborhood Hits	170	Shared Neighborhood Hits	159
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

LAP2_MOUSE
θ value	1.43324e-05 (rank : 197)	NC score	0.144944 (rank : 255)
Query Neighborhood Hits	426	Target Neighborhood Hits	482	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

NHRF2_MOUSE
θ value	1.87187e-05 (rank : 198)	NC score	0.366564 (rank : 153)
Query Neighborhood Hits	426	Target Neighborhood Hits	194	Shared Neighborhood Hits	167
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

SNTB1_HUMAN
θ value	2.44474e-05 (rank : 199)	NC score	0.338912 (rank : 169)
Query Neighborhood Hits	426	Target Neighborhood Hits	157	Shared Neighborhood Hits	148
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	2.44474e-05 (rank : 200)	NC score	0.337922 (rank : 170)
Query Neighborhood Hits	426	Target Neighborhood Hits	160	Shared Neighborhood Hits	146
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

ARHGC_MOUSE
θ value	9.29e-05 (rank : 201)	NC score	0.191702 (rank : 233)
Query Neighborhood Hits	426	Target Neighborhood Hits	344	Shared Neighborhood Hits	153
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RIMS1_HUMAN
θ value	0.000121331 (rank : 202)	NC score	0.165887 (rank : 244)
Query Neighborhood Hits	426	Target Neighborhood Hits	437	Shared Neighborhood Hits	139
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

ARHGC_HUMAN
θ value	0.00020696 (rank : 203)	NC score	0.191748 (rank : 232)
Query Neighborhood Hits	426	Target Neighborhood Hits	351	Shared Neighborhood Hits	149
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RPGF6_HUMAN
θ value	0.00035302 (rank : 204)	NC score	0.227538 (rank : 215)
Query Neighborhood Hits	426	Target Neighborhood Hits	266	Shared Neighborhood Hits	155
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PDZK4_HUMAN
θ value	0.000602161 (rank : 205)	NC score	0.263971 (rank : 191)
Query Neighborhood Hits	426	Target Neighborhood Hits	165	Shared Neighborhood Hits	118
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

APBA2_HUMAN
θ value	0.00134147 (rank : 206)	NC score	0.242164 (rank : 204)
Query Neighborhood Hits	426	Target Neighborhood Hits	220	Shared Neighborhood Hits	151
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.00134147 (rank : 207)	NC score	0.242628 (rank : 203)
Query Neighborhood Hits	426	Target Neighborhood Hits	219	Shared Neighborhood Hits	150
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

PDZK4_MOUSE
θ value	0.00134147 (rank : 208)	NC score	0.264212 (rank : 190)
Query Neighborhood Hits	426	Target Neighborhood Hits	165	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

MPP2_HUMAN
θ value	0.00175202 (rank : 209)	NC score	0.188296 (rank : 237)
Query Neighborhood Hits	426	Target Neighborhood Hits	173	Shared Neighborhood Hits	93
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP4_HUMAN
θ value	0.00175202 (rank : 210)	NC score	0.264435 (rank : 189)
Query Neighborhood Hits	426	Target Neighborhood Hits	205	Shared Neighborhood Hits	139
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDLI2_HUMAN
θ value	0.00228821 (rank : 211)	NC score	0.228403 (rank : 214)
Query Neighborhood Hits	426	Target Neighborhood Hits	245	Shared Neighborhood Hits	128
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

ARHGB_HUMAN
θ value	0.00298849 (rank : 212)	NC score	0.199648 (rank : 230)
Query Neighborhood Hits	426	Target Neighborhood Hits	375	Shared Neighborhood Hits	161
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

MPP2_MOUSE
θ value	0.00390308 (rank : 213)	NC score	0.188180 (rank : 238)
Query Neighborhood Hits	426	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

PCLO_MOUSE
θ value	0.00390308 (rank : 214)	NC score	0.120725 (rank : 267)
Query Neighborhood Hits	426	Target Neighborhood Hits	2275	Shared Neighborhood Hits	186
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TX1B3_HUMAN
θ value	0.00390308 (rank : 215)	NC score	0.378434 (rank : 145)
Query Neighborhood Hits	426	Target Neighborhood Hits	161	Shared Neighborhood Hits	150
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.00390308 (rank : 216)	NC score	0.375781 (rank : 148)
Query Neighborhood Hits	426	Target Neighborhood Hits	158	Shared Neighborhood Hits	147
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

MPP5_HUMAN
θ value	0.00509761 (rank : 217)	NC score	0.250778 (rank : 198)
Query Neighborhood Hits	426	Target Neighborhood Hits	231	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.00509761 (rank : 218)	NC score	0.250280 (rank : 199)
Query Neighborhood Hits	426	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PAR6G_HUMAN
θ value	0.00509761 (rank : 219)	NC score	0.238953 (rank : 207)
Query Neighborhood Hits	426	Target Neighborhood Hits	159	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	0.00509761 (rank : 220)	NC score	0.238887 (rank : 208)
Query Neighborhood Hits	426	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

APBA1_HUMAN
θ value	0.00665767 (rank : 221)	NC score	0.249026 (rank : 202)
Query Neighborhood Hits	426	Target Neighborhood Hits	325	Shared Neighborhood Hits	156
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

APBA3_HUMAN
θ value	0.00665767 (rank : 222)	NC score	0.236177 (rank : 210)
Query Neighborhood Hits	426	Target Neighborhood Hits	201	Shared Neighborhood Hits	139
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

MPP4_MOUSE
θ value	0.00665767 (rank : 223)	NC score	0.239835 (rank : 205)
Query Neighborhood Hits	426	Target Neighborhood Hits	188	Shared Neighborhood Hits	121
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

SYNG_HUMAN
θ value	0.00665767 (rank : 224)	NC score	0.028843 (rank : 359)
Query Neighborhood Hits	426	Target Neighborhood Hits	160	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

RPGF2_HUMAN
θ value	0.00869519 (rank : 225)	NC score	0.190329 (rank : 235)
Query Neighborhood Hits	426	Target Neighborhood Hits	242	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

MAST2_HUMAN
θ value	0.0113563 (rank : 226)	NC score	0.026585 (rank : 366)
Query Neighborhood Hits	426	Target Neighborhood Hits	1189	Shared Neighborhood Hits	137
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NEUM_MOUSE
θ value	0.0113563 (rank : 227)	NC score	0.046521 (rank : 352)
Query Neighborhood Hits	426	Target Neighborhood Hits	149	Shared Neighborhood Hits	16
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

PAR6B_HUMAN
θ value	0.0113563 (rank : 228)	NC score	0.234990 (rank : 211)
Query Neighborhood Hits	426	Target Neighborhood Hits	126	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	0.0113563 (rank : 229)	NC score	0.234658 (rank : 212)
Query Neighborhood Hits	426	Target Neighborhood Hits	128	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PICK1_MOUSE
θ value	0.0113563 (rank : 230)	NC score	0.250169 (rank : 200)
Query Neighborhood Hits	426	Target Neighborhood Hits	131	Shared Neighborhood Hits	121
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
θ value	0.0148317 (rank : 231)	NC score	0.249943 (rank : 201)
Query Neighborhood Hits	426	Target Neighborhood Hits	132	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PAR6A_HUMAN
θ value	0.0252991 (rank : 232)	NC score	0.223656 (rank : 218)
Query Neighborhood Hits	426	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	0.0252991 (rank : 233)	NC score	0.224604 (rank : 217)
Query Neighborhood Hits	426	Target Neighborhood Hits	115	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PDLI2_MOUSE
θ value	0.0252991 (rank : 234)	NC score	0.209982 (rank : 226)
Query Neighborhood Hits	426	Target Neighborhood Hits	220	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI4_MOUSE
θ value	0.0252991 (rank : 235)	NC score	0.148162 (rank : 252)
Query Neighborhood Hits	426	Target Neighborhood Hits	233	Shared Neighborhood Hits	109
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

RGS12_HUMAN
θ value	0.0252991 (rank : 236)	NC score	0.171416 (rank : 243)
Query Neighborhood Hits	426	Target Neighborhood Hits	333	Shared Neighborhood Hits	136
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RHPN1_MOUSE
θ value	0.0252991 (rank : 237)	NC score	0.229577 (rank : 213)
Query Neighborhood Hits	426	Target Neighborhood Hits	154	Shared Neighborhood Hits	129
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

APBA3_MOUSE
θ value	0.0431538 (rank : 238)	NC score	0.221300 (rank : 221)
Query Neighborhood Hits	426	Target Neighborhood Hits	174	Shared Neighborhood Hits	133
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

LDB3_MOUSE
θ value	0.0431538 (rank : 239)	NC score	0.119842 (rank : 268)
Query Neighborhood Hits	426	Target Neighborhood Hits	510	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LIMK2_MOUSE
θ value	0.0563607 (rank : 240)	NC score	0.012359 (rank : 404)
Query Neighborhood Hits	426	Target Neighborhood Hits	998	Shared Neighborhood Hits	83
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LRRF1_HUMAN
θ value	0.0563607 (rank : 241)	NC score	0.028300 (rank : 360)
Query Neighborhood Hits	426	Target Neighborhood Hits	625	Shared Neighborhood Hits	35
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MAST3_HUMAN
θ value	0.0563607 (rank : 242)	NC score	0.026115 (rank : 367)
Query Neighborhood Hits	426	Target Neighborhood Hits	1128	Shared Neighborhood Hits	137
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MPP3_HUMAN
θ value	0.0563607 (rank : 243)	NC score	0.237934 (rank : 209)
Query Neighborhood Hits	426	Target Neighborhood Hits	171	Shared Neighborhood Hits	134
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

SDCB2_HUMAN
θ value	0.0563607 (rank : 244)	NC score	0.190444 (rank : 234)
Query Neighborhood Hits	426	Target Neighborhood Hits	121	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

MPP3_MOUSE
θ value	0.0736092 (rank : 245)	NC score	0.239587 (rank : 206)
Query Neighborhood Hits	426	Target Neighborhood Hits	165	Shared Neighborhood Hits	133
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

GIPC3_HUMAN
θ value	0.0961366 (rank : 246)	NC score	0.086907 (rank : 286)
Query Neighborhood Hits	426	Target Neighborhood Hits	52	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	0.0961366 (rank : 247)	NC score	0.085669 (rank : 287)
Query Neighborhood Hits	426	Target Neighborhood Hits	53	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

LDB3_HUMAN
θ value	0.0961366 (rank : 248)	NC score	0.118017 (rank : 270)
Query Neighborhood Hits	426	Target Neighborhood Hits	497	Shared Neighborhood Hits	108
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PSCBP_MOUSE
θ value	0.0961366 (rank : 249)	NC score	0.220931 (rank : 222)
Query Neighborhood Hits	426	Target Neighborhood Hits	118	Shared Neighborhood Hits	111
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

SYNP2_MOUSE
θ value	0.0961366 (rank : 250)	NC score	0.172480 (rank : 242)
Query Neighborhood Hits	426	Target Neighborhood Hits	252	Shared Neighborhood Hits	120
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

CSPG2_MOUSE
θ value	0.125558 (rank : 251)	NC score	0.005882 (rank : 436)
Query Neighborhood Hits	426	Target Neighborhood Hits	711	Shared Neighborhood Hits	26
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

HUWE1_MOUSE
θ value	0.125558 (rank : 252)	NC score	0.012504 (rank : 402)
Query Neighborhood Hits	426	Target Neighborhood Hits	406	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

MY18A_MOUSE
θ value	0.125558 (rank : 253)	NC score	0.057674 (rank : 321)
Query Neighborhood Hits	426	Target Neighborhood Hits	1989	Shared Neighborhood Hits	179
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PDLI4_HUMAN
θ value	0.125558 (rank : 254)	NC score	0.143936 (rank : 256)
Query Neighborhood Hits	426	Target Neighborhood Hits	245	Shared Neighborhood Hits	106
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

KRIT1_HUMAN
θ value	0.163984 (rank : 255)	NC score	0.073055 (rank : 299)
Query Neighborhood Hits	426	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

NTKL_HUMAN
θ value	0.163984 (rank : 256)	NC score	0.017187 (rank : 383)
Query Neighborhood Hits	426	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

LAP2A_HUMAN
θ value	0.21417 (rank : 257)	NC score	0.018399 (rank : 378)
Query Neighborhood Hits	426	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

MAP2_HUMAN
θ value	0.21417 (rank : 258)	NC score	0.012405 (rank : 403)
Query Neighborhood Hits	426	Target Neighborhood Hits	348	Shared Neighborhood Hits	19
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MAST2_MOUSE
θ value	0.21417 (rank : 259)	NC score	0.024617 (rank : 368)
Query Neighborhood Hits	426	Target Neighborhood Hits	1110	Shared Neighborhood Hits	136
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SAFB2_HUMAN
θ value	0.21417 (rank : 260)	NC score	0.007886 (rank : 428)
Query Neighborhood Hits	426	Target Neighborhood Hits	720	Shared Neighborhood Hits	29
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SRRM2_MOUSE
θ value	0.21417 (rank : 261)	NC score	0.037507 (rank : 354)
Query Neighborhood Hits	426	Target Neighborhood Hits	1470	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

GIPC1_HUMAN
θ value	0.279714 (rank : 262)	NC score	0.140562 (rank : 257)
Query Neighborhood Hits	426	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

JIP4_MOUSE
θ value	0.279714 (rank : 263)	NC score	0.015035 (rank : 389)
Query Neighborhood Hits	426	Target Neighborhood Hits	593	Shared Neighborhood Hits	33
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

KRIT1_MOUSE
θ value	0.279714 (rank : 264)	NC score	0.068202 (rank : 305)
Query Neighborhood Hits	426	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MYCN_HUMAN
θ value	0.279714 (rank : 265)	NC score	0.010609 (rank : 409)
Query Neighborhood Hits	426	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

NKTR_HUMAN
θ value	0.279714 (rank : 266)	NC score	0.014486 (rank : 392)
Query Neighborhood Hits	426	Target Neighborhood Hits	658	Shared Neighborhood Hits	44
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PSCBP_HUMAN
θ value	0.279714 (rank : 267)	NC score	0.205889 (rank : 229)
Query Neighborhood Hits	426	Target Neighborhood Hits	123	Shared Neighborhood Hits	112
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RHPN1_HUMAN
θ value	0.279714 (rank : 268)	NC score	0.213292 (rank : 225)
Query Neighborhood Hits	426	Target Neighborhood Hits	158	Shared Neighborhood Hits	123
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SDCB1_HUMAN
θ value	0.279714 (rank : 269)	NC score	0.222786 (rank : 220)
Query Neighborhood Hits	426	Target Neighborhood Hits	150	Shared Neighborhood Hits	142
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	0.279714 (rank : 270)	NC score	0.223120 (rank : 219)
Query Neighborhood Hits	426	Target Neighborhood Hits	144	Shared Neighborhood Hits	135
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

URP1_HUMAN
θ value	0.279714 (rank : 271)	NC score	0.027304 (rank : 364)
Query Neighborhood Hits	426	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQL6, Q8IX34, Q8IYH2, Q9NWM2, Q9NXQ3	Gene names	URP1, C20orf42, KIND1
Domain Architecture
Description	Unc-112-related protein 1 (Kindlin-1) (Kindlerin) (Kindlin syndrome protein).

EM55_HUMAN
θ value	0.365318 (rank : 272)	NC score	0.207899 (rank : 227)
Query Neighborhood Hits	426	Target Neighborhood Hits	228	Shared Neighborhood Hits	128
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

GIPC1_MOUSE
θ value	0.365318 (rank : 273)	NC score	0.145837 (rank : 254)
Query Neighborhood Hits	426	Target Neighborhood Hits	92	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

LIMK2_HUMAN
θ value	0.365318 (rank : 274)	NC score	0.009457 (rank : 416)
Query Neighborhood Hits	426	Target Neighborhood Hits	986	Shared Neighborhood Hits	86
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

MAST4_HUMAN
θ value	0.365318 (rank : 275)	NC score	0.027578 (rank : 362)
Query Neighborhood Hits	426	Target Neighborhood Hits	1804	Shared Neighborhood Hits	161
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MPIP1_HUMAN
θ value	0.365318 (rank : 276)	NC score	0.011423 (rank : 408)
Query Neighborhood Hits	426	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P30304, Q8IZH5, Q96IL3, Q9H2F2	Gene names	CDC25A
Domain Architecture
Description	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A).

PAWR_HUMAN
θ value	0.365318 (rank : 277)	NC score	0.026892 (rank : 365)
Query Neighborhood Hits	426	Target Neighborhood Hits	252	Shared Neighborhood Hits	15
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

PDLI5_MOUSE
θ value	0.365318 (rank : 278)	NC score	0.110370 (rank : 273)
Query Neighborhood Hits	426	Target Neighborhood Hits	287	Shared Neighborhood Hits	113
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

TOIP2_HUMAN
θ value	0.365318 (rank : 279)	NC score	0.014236 (rank : 393)
Query Neighborhood Hits	426	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

CC14B_MOUSE
θ value	0.47712 (rank : 280)	NC score	0.118433 (rank : 269)
Query Neighborhood Hits	426	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

GIPC2_HUMAN
θ value	0.47712 (rank : 281)	NC score	0.121946 (rank : 266)
Query Neighborhood Hits	426	Target Neighborhood Hits	93	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

PDZD6_HUMAN
θ value	0.47712 (rank : 282)	NC score	0.116805 (rank : 271)
Query Neighborhood Hits	426	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

SYP2L_HUMAN
θ value	0.47712 (rank : 283)	NC score	0.188111 (rank : 239)
Query Neighborhood Hits	426	Target Neighborhood Hits	400	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TACC3_HUMAN
θ value	0.47712 (rank : 284)	NC score	0.021407 (rank : 373)
Query Neighborhood Hits	426	Target Neighborhood Hits	779	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CD2L7_HUMAN
θ value	0.62314 (rank : 285)	NC score	-0.006372 (rank : 476)
Query Neighborhood Hits	426	Target Neighborhood Hits	1275	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

E2AK4_HUMAN
θ value	0.62314 (rank : 286)	NC score	-0.002571 (rank : 468)
Query Neighborhood Hits	426	Target Neighborhood Hits	1012	Shared Neighborhood Hits	41
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

EM55_MOUSE
θ value	0.62314 (rank : 287)	NC score	0.206533 (rank : 228)
Query Neighborhood Hits	426	Target Neighborhood Hits	221	Shared Neighborhood Hits	126
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

LAP2B_HUMAN
θ value	0.62314 (rank : 288)	NC score	0.017796 (rank : 380)
Query Neighborhood Hits	426	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	P42167, Q14861	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

MY18A_HUMAN
θ value	0.62314 (rank : 289)	NC score	0.054069 (rank : 336)
Query Neighborhood Hits	426	Target Neighborhood Hits	1929	Shared Neighborhood Hits	181
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NTKL_MOUSE
θ value	0.62314 (rank : 290)	NC score	0.009944 (rank : 413)
Query Neighborhood Hits	426	Target Neighborhood Hits	326	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

RNF34_HUMAN
θ value	0.62314 (rank : 291)	NC score	0.019699 (rank : 376)
Query Neighborhood Hits	426	Target Neighborhood Hits	153	Shared Neighborhood Hits	10
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

SDCB2_MOUSE
θ value	0.62314 (rank : 292)	NC score	0.189077 (rank : 236)
Query Neighborhood Hits	426	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

YTDC1_HUMAN
θ value	0.62314 (rank : 293)	NC score	0.014547 (rank : 391)
Query Neighborhood Hits	426	Target Neighborhood Hits	458	Shared Neighborhood Hits	36
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

BRCA2_MOUSE
θ value	0.813845 (rank : 294)	NC score	0.016493 (rank : 385)
Query Neighborhood Hits	426	Target Neighborhood Hits	222	Shared Neighborhood Hits	12
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

CC14A_HUMAN
θ value	0.813845 (rank : 295)	NC score	0.105736 (rank : 276)
Query Neighborhood Hits	426	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
θ value	0.813845 (rank : 296)	NC score	0.108004 (rank : 275)
Query Neighborhood Hits	426	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14B_HUMAN
θ value	0.813845 (rank : 297)	NC score	0.115904 (rank : 272)
Query Neighborhood Hits	426	Target Neighborhood Hits	114	Shared Neighborhood Hits	61
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

GAB1_HUMAN
θ value	0.813845 (rank : 298)	NC score	0.012091 (rank : 406)
Query Neighborhood Hits	426	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

SYAM_MOUSE
θ value	0.813845 (rank : 299)	NC score	0.013843 (rank : 394)
Query Neighborhood Hits	426	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q14CH7, Q68FH3, Q69ZM9	Gene names	Aarsl, Aars2, Kiaa1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

SYNP2_HUMAN
θ value	0.813845 (rank : 300)	NC score	0.133065 (rank : 261)
Query Neighborhood Hits	426	Target Neighborhood Hits	323	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYT14_HUMAN
θ value	0.813845 (rank : 301)	NC score	0.006519 (rank : 433)
Query Neighborhood Hits	426	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

LIMK1_MOUSE
θ value	1.06291 (rank : 302)	NC score	0.009185 (rank : 419)
Query Neighborhood Hits	426	Target Neighborhood Hits	1008	Shared Neighborhood Hits	96
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

RAI14_HUMAN
θ value	1.06291 (rank : 303)	NC score	0.004918 (rank : 442)
Query Neighborhood Hits	426	Target Neighborhood Hits	1367	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

SYAM_HUMAN
θ value	1.06291 (rank : 304)	NC score	0.013155 (rank : 398)
Query Neighborhood Hits	426	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTZ9, Q8N198, Q96D02, Q9ULF0	Gene names	AARSL, AARS2, KIAA1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

AMOT_HUMAN
θ value	1.38821 (rank : 305)	NC score	0.012043 (rank : 407)
Query Neighborhood Hits	426	Target Neighborhood Hits	712	Shared Neighborhood Hits	39
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CNKR2_HUMAN
θ value	1.38821 (rank : 306)	NC score	0.084359 (rank : 289)
Query Neighborhood Hits	426	Target Neighborhood Hits	197	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	1.38821 (rank : 307)	NC score	0.084425 (rank : 288)
Query Neighborhood Hits	426	Target Neighborhood Hits	197	Shared Neighborhood Hits	60
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DNL1_HUMAN
θ value	1.38821 (rank : 308)	NC score	0.012924 (rank : 399)
Query Neighborhood Hits	426	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

FMR1_HUMAN
θ value	1.38821 (rank : 309)	NC score	0.008404 (rank : 424)
Query Neighborhood Hits	426	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

HUWE1_HUMAN
θ value	1.38821 (rank : 310)	NC score	0.010062 (rank : 412)
Query Neighborhood Hits	426	Target Neighborhood Hits	443	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

NOLC1_HUMAN
θ value	1.38821 (rank : 311)	NC score	0.024148 (rank : 371)
Query Neighborhood Hits	426	Target Neighborhood Hits	452	Shared Neighborhood Hits	35
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TGON2_HUMAN
θ value	1.38821 (rank : 312)	NC score	0.020137 (rank : 375)
Query Neighborhood Hits	426	Target Neighborhood Hits	1037	Shared Neighborhood Hits	67
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TP4A3_MOUSE
θ value	1.38821 (rank : 313)	NC score	0.075779 (rank : 295)
Query Neighborhood Hits	426	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

DAXX_HUMAN
θ value	1.81305 (rank : 314)	NC score	0.016837 (rank : 384)
Query Neighborhood Hits	426	Target Neighborhood Hits	207	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DOK7_HUMAN
θ value	1.81305 (rank : 315)	NC score	0.013409 (rank : 396)
Query Neighborhood Hits	426	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q18PE1, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1	Gene names	DOK7, C4orf25
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

DUS23_HUMAN
θ value	1.81305 (rank : 316)	NC score	0.218196 (rank : 223)
Query Neighborhood Hits	426	Target Neighborhood Hits	98	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

GIPC2_MOUSE
θ value	1.81305 (rank : 317)	NC score	0.081883 (rank : 292)
Query Neighborhood Hits	426	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

MYO7A_HUMAN
θ value	1.81305 (rank : 318)	NC score	0.031266 (rank : 358)
Query Neighborhood Hits	426	Target Neighborhood Hits	209	Shared Neighborhood Hits	35
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	1.81305 (rank : 319)	NC score	0.031652 (rank : 357)
Query Neighborhood Hits	426	Target Neighborhood Hits	235	Shared Neighborhood Hits	34
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

NUB1_HUMAN
θ value	1.81305 (rank : 320)	NC score	0.010188 (rank : 411)
Query Neighborhood Hits	426	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5A7, O95422, Q8IX22, Q9BXR2	Gene names	NUB1, NYREN18
Domain Architecture
Description	NEDD8 ultimate buster 1 (NY-REN-18 antigen).

PDLI3_HUMAN
θ value	1.81305 (rank : 321)	NC score	0.147877 (rank : 253)
Query Neighborhood Hits	426	Target Neighborhood Hits	199	Shared Neighborhood Hits	105
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PGCB_HUMAN
θ value	1.81305 (rank : 322)	NC score	0.000402 (rank : 460)
Query Neighborhood Hits	426	Target Neighborhood Hits	478	Shared Neighborhood Hits	16
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SRRM2_HUMAN
θ value	1.81305 (rank : 323)	NC score	0.043119 (rank : 353)
Query Neighborhood Hits	426	Target Neighborhood Hits	1296	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SV2C_HUMAN
θ value	1.81305 (rank : 324)	NC score	0.005121 (rank : 440)
Query Neighborhood Hits	426	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

DUS23_MOUSE
θ value	2.36792 (rank : 325)	NC score	0.224987 (rank : 216)
Query Neighborhood Hits	426	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

JIP4_HUMAN
θ value	2.36792 (rank : 326)	NC score	0.013370 (rank : 397)
Query Neighborhood Hits	426	Target Neighborhood Hits	585	Shared Neighborhood Hits	29
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

LIMK1_HUMAN
θ value	2.36792 (rank : 327)	NC score	0.009769 (rank : 415)
Query Neighborhood Hits	426	Target Neighborhood Hits	1005	Shared Neighborhood Hits	94
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

PDLI7_HUMAN
θ value	2.36792 (rank : 328)	NC score	0.097742 (rank : 279)
Query Neighborhood Hits	426	Target Neighborhood Hits	547	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SHAN1_HUMAN
θ value	2.36792 (rank : 329)	NC score	0.094184 (rank : 282)
Query Neighborhood Hits	426	Target Neighborhood Hits	1041	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TAOK1_HUMAN
θ value	2.36792 (rank : 330)	NC score	0.001182 (rank : 457)
Query Neighborhood Hits	426	Target Neighborhood Hits	1734	Shared Neighborhood Hits	63
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TAOK1_MOUSE
θ value	2.36792 (rank : 331)	NC score	0.001526 (rank : 454)
Query Neighborhood Hits	426	Target Neighborhood Hits	1720	Shared Neighborhood Hits	64
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

WNK2_HUMAN
θ value	2.36792 (rank : 332)	NC score	-0.002683 (rank : 470)
Query Neighborhood Hits	426	Target Neighborhood Hits	1407	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

XRCC4_MOUSE
θ value	2.36792 (rank : 333)	NC score	0.008958 (rank : 420)
Query Neighborhood Hits	426	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q924T3, Q8BKC9, Q8BU02, Q9D6U6	Gene names	Xrcc4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

ZFP95_HUMAN
θ value	2.36792 (rank : 334)	NC score	-0.012338 (rank : 481)
Query Neighborhood Hits	426	Target Neighborhood Hits	775	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

ZRAB2_HUMAN
θ value	2.36792 (rank : 335)	NC score	0.019617 (rank : 377)
Query Neighborhood Hits	426	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

DMP1_MOUSE
θ value	3.0926 (rank : 336)	NC score	0.034952 (rank : 355)
Query Neighborhood Hits	426	Target Neighborhood Hits	498	Shared Neighborhood Hits	38
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

HTRA3_HUMAN
θ value	3.0926 (rank : 337)	NC score	0.048195 (rank : 350)
Query Neighborhood Hits	426	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	3.0926 (rank : 338)	NC score	0.051647 (rank : 344)
Query Neighborhood Hits	426	Target Neighborhood Hits	156	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

LIPA2_HUMAN
θ value	3.0926 (rank : 339)	NC score	0.014593 (rank : 390)
Query Neighborhood Hits	426	Target Neighborhood Hits	1044	Shared Neighborhood Hits	53
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
θ value	3.0926 (rank : 340)	NC score	0.018395 (rank : 379)
Query Neighborhood Hits	426	Target Neighborhood Hits	1282	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYOM2_HUMAN
θ value	3.0926 (rank : 341)	NC score	0.047031 (rank : 351)
Query Neighborhood Hits	426	Target Neighborhood Hits	341	Shared Neighborhood Hits	19
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NIPBL_HUMAN
θ value	3.0926 (rank : 342)	NC score	0.027494 (rank : 363)
Query Neighborhood Hits	426	Target Neighborhood Hits	1311	Shared Neighborhood Hits	91
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PDLI3_MOUSE
θ value	3.0926 (rank : 343)	NC score	0.136903 (rank : 258)
Query Neighborhood Hits	426	Target Neighborhood Hits	197	Shared Neighborhood Hits	101
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SET1A_HUMAN
θ value	3.0926 (rank : 344)	NC score	0.016025 (rank : 386)
Query Neighborhood Hits	426	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TP4A3_HUMAN
θ value	3.0926 (rank : 345)	NC score	0.080405 (rank : 293)
Query Neighborhood Hits	426	Target Neighborhood Hits	62	Shared Neighborhood Hits	36
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

ZFAN3_MOUSE
θ value	3.0926 (rank : 346)	NC score	0.009216 (rank : 418)
Query Neighborhood Hits	426	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q497H0, Q8K230, Q8R2V7, Q8R3V1	Gene names	Zfand3, Tex27
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 3 (Testis-expressed sequence 27).

BRAF1_HUMAN
θ value	4.03905 (rank : 347)	NC score	-0.007829 (rank : 480)
Query Neighborhood Hits	426	Target Neighborhood Hits	883	Shared Neighborhood Hits	30
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

FXR2_MOUSE
θ value	4.03905 (rank : 348)	NC score	0.006842 (rank : 429)
Query Neighborhood Hits	426	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

GGA1_MOUSE
θ value	4.03905 (rank : 349)	NC score	0.003361 (rank : 450)
Query Neighborhood Hits	426	Target Neighborhood Hits	128	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

MP2K4_HUMAN
θ value	4.03905 (rank : 350)	NC score	-0.004180 (rank : 472)
Query Neighborhood Hits	426	Target Neighborhood Hits	832	Shared Neighborhood Hits	31
SwissProt Accessions	P45985, Q5U0B8	Gene names	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

MP2K4_MOUSE
θ value	4.03905 (rank : 351)	NC score	-0.004171 (rank : 471)
Query Neighborhood Hits	426	Target Neighborhood Hits	833	Shared Neighborhood Hits	31
SwissProt Accessions	P47809	Gene names	Map2k4, Jnkk1, Prkmk4, Sek1, Serk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SEK1).

MST4_HUMAN
θ value	4.03905 (rank : 352)	NC score	-0.007216 (rank : 478)
Query Neighborhood Hits	426	Target Neighborhood Hits	852	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MST4_MOUSE
θ value	4.03905 (rank : 353)	NC score	-0.007223 (rank : 479)
Query Neighborhood Hits	426	Target Neighborhood Hits	860	Shared Neighborhood Hits	29
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

NR4A1_MOUSE
θ value	4.03905 (rank : 354)	NC score	-0.002610 (rank : 469)
Query Neighborhood Hits	426	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

PDLI5_HUMAN
θ value	4.03905 (rank : 355)	NC score	0.108732 (rank : 274)
Query Neighborhood Hits	426	Target Neighborhood Hits	322	Shared Neighborhood Hits	114
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PER1_HUMAN
θ value	4.03905 (rank : 356)	NC score	0.004906 (rank : 443)
Query Neighborhood Hits	426	Target Neighborhood Hits	215	Shared Neighborhood Hits	13
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

RM11_HUMAN
θ value	4.03905 (rank : 357)	NC score	0.009809 (rank : 414)
Query Neighborhood Hits	426	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3B7, Q96Q73	Gene names	MRPL11
Domain Architecture
Description	39S ribosomal protein L11, mitochondrial precursor (L11mt) (MRP-L11).

SHAN2_HUMAN
θ value	4.03905 (rank : 358)	NC score	0.148677 (rank : 251)
Query Neighborhood Hits	426	Target Neighborhood Hits	346	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

TAOK3_HUMAN
θ value	4.03905 (rank : 359)	NC score	-0.001541 (rank : 467)
Query Neighborhood Hits	426	Target Neighborhood Hits	1494	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TDRD3_MOUSE
θ value	4.03905 (rank : 360)	NC score	0.006538 (rank : 432)
Query Neighborhood Hits	426	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W18, Q8BZW6	Gene names	Tdrd3
Domain Architecture
Description	Tudor domain-containing protein 3.

TP4A2_HUMAN
θ value	4.03905 (rank : 361)	NC score	0.082181 (rank : 290)
Query Neighborhood Hits	426	Target Neighborhood Hits	56	Shared Neighborhood Hits	37
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	4.03905 (rank : 362)	NC score	0.082181 (rank : 291)
Query Neighborhood Hits	426	Target Neighborhood Hits	56	Shared Neighborhood Hits	37
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

ZC3H6_HUMAN
θ value	4.03905 (rank : 363)	NC score	0.004255 (rank : 446)
Query Neighborhood Hits	426	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

AF9_HUMAN
θ value	5.27518 (rank : 364)	NC score	0.028106 (rank : 361)
Query Neighborhood Hits	426	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

BOP1_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.001166 (rank : 458)
Query Neighborhood Hits	426	Target Neighborhood Hits	257	Shared Neighborhood Hits	6
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

CASC3_MOUSE
θ value	5.27518 (rank : 366)	NC score	0.012330 (rank : 405)
Query Neighborhood Hits	426	Target Neighborhood Hits	333	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CKAP5_HUMAN
θ value	5.27518 (rank : 367)	NC score	0.010237 (rank : 410)
Query Neighborhood Hits	426	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

CLH1_HUMAN
θ value	5.27518 (rank : 368)	NC score	0.006542 (rank : 431)
Query Neighborhood Hits	426	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q00610, Q6N0A0, Q86TF2	Gene names	CLTC, CLH17, KIAA0034
Domain Architecture
Description	Clathrin heavy chain 1 (CLH-17).

CLH_MOUSE
θ value	5.27518 (rank : 369)	NC score	0.006545 (rank : 430)
Query Neighborhood Hits	426	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FD5	Gene names	Cltc
Domain Architecture	No domain graphic available
Description	Clathrin heavy chain.

CSKP_HUMAN
θ value	5.27518 (rank : 370)	NC score	0.062254 (rank : 311)
Query Neighborhood Hits	426	Target Neighborhood Hits	1022	Shared Neighborhood Hits	137
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	5.27518 (rank : 371)	NC score	0.059966 (rank : 315)
Query Neighborhood Hits	426	Target Neighborhood Hits	1027	Shared Neighborhood Hits	138
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

DCP1B_HUMAN
θ value	5.27518 (rank : 372)	NC score	0.005701 (rank : 438)
Query Neighborhood Hits	426	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

EVI1_MOUSE
θ value	5.27518 (rank : 373)	NC score	-0.012724 (rank : 484)
Query Neighborhood Hits	426	Target Neighborhood Hits	826	Shared Neighborhood Hits	10
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

GYS1_HUMAN
θ value	5.27518 (rank : 374)	NC score	0.008369 (rank : 425)
Query Neighborhood Hits	426	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P13807	Gene names	GYS1, GYS
Domain Architecture
Description	Glycogen [starch] synthase, muscle (EC 2.4.1.11).

GYS1_MOUSE
θ value	5.27518 (rank : 375)	NC score	0.008624 (rank : 422)
Query Neighborhood Hits	426	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1E4	Gene names	Gys1, Gys
Domain Architecture
Description	Glycogen [starch] synthase, muscle (EC 2.4.1.11).

GYS3_MOUSE
θ value	5.27518 (rank : 376)	NC score	0.008594 (rank : 423)
Query Neighborhood Hits	426	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P54859	Gene names	Gys3
Domain Architecture
Description	Glycogen [starch] synthase, brain (EC 2.4.1.11).

JADE3_HUMAN
θ value	5.27518 (rank : 377)	NC score	-0.000126 (rank : 462)
Query Neighborhood Hits	426	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

K1C18_HUMAN
θ value	5.27518 (rank : 378)	NC score	-0.000155 (rank : 463)
Query Neighborhood Hits	426	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

MAST1_HUMAN
θ value	5.27518 (rank : 379)	NC score	0.023576 (rank : 372)
Query Neighborhood Hits	426	Target Neighborhood Hits	1146	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	5.27518 (rank : 380)	NC score	0.024231 (rank : 370)
Query Neighborhood Hits	426	Target Neighborhood Hits	1123	Shared Neighborhood Hits	139
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NGAP_HUMAN
θ value	5.27518 (rank : 381)	NC score	0.008806 (rank : 421)
Query Neighborhood Hits	426	Target Neighborhood Hits	517	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

RBM28_HUMAN
θ value	5.27518 (rank : 382)	NC score	-0.000429 (rank : 464)
Query Neighborhood Hits	426	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

SHAN2_MOUSE
θ value	5.27518 (rank : 383)	NC score	0.133132 (rank : 260)
Query Neighborhood Hits	426	Target Neighborhood Hits	446	Shared Neighborhood Hits	121
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SV2C_MOUSE
θ value	5.27518 (rank : 384)	NC score	0.003957 (rank : 447)
Query Neighborhood Hits	426	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZS6	Gene names	Sv2c, Kiaa1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C (Synaptic vesicle protein 2C).

SYP2L_MOUSE
θ value	5.27518 (rank : 385)	NC score	0.136733 (rank : 259)
Query Neighborhood Hits	426	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TCAL5_HUMAN
θ value	5.27518 (rank : 386)	NC score	0.009244 (rank : 417)
Query Neighborhood Hits	426	Target Neighborhood Hits	806	Shared Neighborhood Hits	43
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TITIN_HUMAN
θ value	5.27518 (rank : 387)	NC score	0.033107 (rank : 356)
Query Neighborhood Hits	426	Target Neighborhood Hits	2923	Shared Neighborhood Hits	133
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN319_MOUSE
θ value	5.27518 (rank : 388)	NC score	-0.012574 (rank : 482)
Query Neighborhood Hits	426	Target Neighborhood Hits	762	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERR8	Gene names	Znf319, Zfp319
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

ZN467_MOUSE
θ value	5.27518 (rank : 389)	NC score	-0.012643 (rank : 483)
Query Neighborhood Hits	426	Target Neighborhood Hits	794	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZL0, Q9JJ98	Gene names	Znf467, Ezi, Zfp467
Domain Architecture	No domain graphic available
Description	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI).

AFF2_MOUSE
θ value	6.88961 (rank : 390)	NC score	0.005957 (rank : 435)
Query Neighborhood Hits	426	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

AP1G2_HUMAN
θ value	6.88961 (rank : 391)	NC score	0.002259 (rank : 453)
Query Neighborhood Hits	426	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

BSCL2_HUMAN
θ value	6.88961 (rank : 392)	NC score	0.007957 (rank : 427)
Query Neighborhood Hits	426	Target Neighborhood Hits	148	Shared Neighborhood Hits	13
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

CD2L2_HUMAN
θ value	6.88961 (rank : 393)	NC score	-0.004916 (rank : 475)
Query Neighborhood Hits	426	Target Neighborhood Hits	1439	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CD2_HUMAN
θ value	6.88961 (rank : 394)	NC score	0.005994 (rank : 434)
Query Neighborhood Hits	426	Target Neighborhood Hits	504	Shared Neighborhood Hits	20
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

DMXL1_HUMAN
θ value	6.88961 (rank : 395)	NC score	0.000781 (rank : 459)
Query Neighborhood Hits	426	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

DUS5_HUMAN
θ value	6.88961 (rank : 396)	NC score	0.017591 (rank : 381)
Query Neighborhood Hits	426	Target Neighborhood Hits	82	Shared Neighborhood Hits	26
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

MCPH1_HUMAN
θ value	6.88961 (rank : 397)	NC score	0.003926 (rank : 448)
Query Neighborhood Hits	426	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

MPP6_HUMAN
θ value	6.88961 (rank : 398)	NC score	0.176376 (rank : 241)
Query Neighborhood Hits	426	Target Neighborhood Hits	180	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	6.88961 (rank : 399)	NC score	0.178778 (rank : 240)
Query Neighborhood Hits	426	Target Neighborhood Hits	187	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MYO5A_MOUSE
θ value	6.88961 (rank : 400)	NC score	0.013590 (rank : 395)
Query Neighborhood Hits	426	Target Neighborhood Hits	1117	Shared Neighborhood Hits	49
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

NEUM_HUMAN
θ value	6.88961 (rank : 401)	NC score	0.020433 (rank : 374)
Query Neighborhood Hits	426	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NVL_MOUSE
θ value	6.88961 (rank : 402)	NC score	-0.001433 (rank : 466)
Query Neighborhood Hits	426	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PCD19_HUMAN
θ value	6.88961 (rank : 403)	NC score	-0.004465 (rank : 474)
Query Neighborhood Hits	426	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAB3, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3	Gene names	PCDH19, KIAA1313
Domain Architecture
Description	Protocadherin-19 precursor.

PCD19_MOUSE
θ value	6.88961 (rank : 404)	NC score	-0.004457 (rank : 473)
Query Neighborhood Hits	426	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TF3, Q8BL13	Gene names	Pcdh19, Kiaa1313
Domain Architecture	No domain graphic available
Description	Protocadherin-19 precursor.

PKN1_HUMAN
θ value	6.88961 (rank : 405)	NC score	-0.006463 (rank : 477)
Query Neighborhood Hits	426	Target Neighborhood Hits	886	Shared Neighborhood Hits	32
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

SI1L2_MOUSE
θ value	6.88961 (rank : 406)	NC score	0.024362 (rank : 369)
Query Neighborhood Hits	426	Target Neighborhood Hits	124	Shared Neighborhood Hits	41
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

TAOK3_MOUSE
θ value	6.88961 (rank : 407)	NC score	-0.001044 (rank : 465)
Query Neighborhood Hits	426	Target Neighborhood Hits	1458	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

ZC3H3_MOUSE
θ value	6.88961 (rank : 408)	NC score	0.008268 (rank : 426)
Query Neighborhood Hits	426	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZP1_MOUSE
θ value	6.88961 (rank : 409)	NC score	0.002890 (rank : 451)
Query Neighborhood Hits	426	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q62005, Q62016	Gene names	Zp1
Domain Architecture
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

AKAP6_HUMAN
θ value	8.99809 (rank : 410)	NC score	0.004731 (rank : 444)
Query Neighborhood Hits	426	Target Neighborhood Hits	263	Shared Neighborhood Hits	13
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

ATRX_HUMAN
θ value	8.99809 (rank : 411)	NC score	0.004336 (rank : 445)
Query Neighborhood Hits	426	Target Neighborhood Hits	842	Shared Neighborhood Hits	43
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

AUTS2_HUMAN
θ value	8.99809 (rank : 412)	NC score	0.017372 (rank : 382)
Query Neighborhood Hits	426	Target Neighborhood Hits	342	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAT2_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.015555 (rank : 387)
Query Neighborhood Hits	426	Target Neighborhood Hits	931	Shared Neighborhood Hits	53
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BRD4_HUMAN
θ value	8.99809 (rank : 414)	NC score	0.002369 (rank : 452)
Query Neighborhood Hits	426	Target Neighborhood Hits	851	Shared Neighborhood Hits	44
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CD017_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.005761 (rank : 437)
Query Neighborhood Hits	426	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q53FE4, Q6FI84, Q6IS77, Q9H0D9	Gene names	C4orf17
Domain Architecture	No domain graphic available
Description	Protein C4orf17.

CN155_HUMAN
θ value	8.99809 (rank : 416)	NC score	0.012896 (rank : 400)
Query Neighborhood Hits	426	Target Neighborhood Hits	385	Shared Neighborhood Hits	30
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

DMN_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.015193 (rank : 388)
Query Neighborhood Hits	426	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

RYR2_HUMAN
θ value	8.99809 (rank : 418)	NC score	0.001490 (rank : 455)
Query Neighborhood Hits	426	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

SENP7_HUMAN
θ value	8.99809 (rank : 419)	NC score	0.003734 (rank : 449)
Query Neighborhood Hits	426	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

STX18_MOUSE
θ value	8.99809 (rank : 420)	NC score	0.005698 (rank : 439)
Query Neighborhood Hits	426	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDS8, Q3TDJ0, Q9D8T6	Gene names	Stx18
Domain Architecture	No domain graphic available
Description	Syntaxin-18.

SYNPO_HUMAN
θ value	8.99809 (rank : 421)	NC score	0.012702 (rank : 401)
Query Neighborhood Hits	426	Target Neighborhood Hits	281	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TP4A1_HUMAN
θ value	8.99809 (rank : 422)	NC score	0.094804 (rank : 280)
Query Neighborhood Hits	426	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	8.99809 (rank : 423)	NC score	0.094804 (rank : 281)
Query Neighborhood Hits	426	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TULP1_MOUSE
θ value	8.99809 (rank : 424)	NC score	0.001288 (rank : 456)
Query Neighborhood Hits	426	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

XRCC1_MOUSE
θ value	8.99809 (rank : 425)	NC score	0.005081 (rank : 441)
Query Neighborhood Hits	426	Target Neighborhood Hits	242	Shared Neighborhood Hits	17
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZFYV9_HUMAN
θ value	8.99809 (rank : 426)	NC score	0.000060 (rank : 461)
Query Neighborhood Hits	426	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

APXL_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.155059 (rank : 247)
Query Neighborhood Hits	426	Target Neighborhood Hits	553	Shared Neighborhood Hits	110
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CA106_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.056960 (rank : 324)
Query Neighborhood Hits	426	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.055668 (rank : 328)
Query Neighborhood Hits	426	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CAR11_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.056675 (rank : 325)
Query Neighborhood Hits	426	Target Neighborhood Hits	690	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CDKN3_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.059638 (rank : 316)
Query Neighborhood Hits	426	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

CNTN2_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.051409 (rank : 346)
Query Neighborhood Hits	426	Target Neighborhood Hits	440	Shared Neighborhood Hits	16
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.051287 (rank : 347)
Query Neighborhood Hits	426	Target Neighborhood Hits	450	Shared Neighborhood Hits	15
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN5_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.053082 (rank : 338)
Query Neighborhood Hits	426	Target Neighborhood Hits	446	Shared Neighborhood Hits	17
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN5_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.051979 (rank : 342)
Query Neighborhood Hits	426	Target Neighborhood Hits	434	Shared Neighborhood Hits	18
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CO7A1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.052798 (rank : 340)
Query Neighborhood Hits	426	Target Neighborhood Hits	807	Shared Neighborhood Hits	36
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COCA1_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.065942 (rank : 308)
Query Neighborhood Hits	426	Target Neighborhood Hits	458	Shared Neighborhood Hits	27
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.067307 (rank : 306)
Query Neighborhood Hits	426	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.054930 (rank : 332)
Query Neighborhood Hits	426	Target Neighborhood Hits	402	Shared Neighborhood Hits	24
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DCC_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.076408 (rank : 294)
Query Neighborhood Hits	426	Target Neighborhood Hits	583	Shared Neighborhood Hits	31
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.074989 (rank : 296)
Query Neighborhood Hits	426	Target Neighborhood Hits	896	Shared Neighborhood Hits	51
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCAM_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.054659 (rank : 335)
Query Neighborhood Hits	426	Target Neighborhood Hits	524	Shared Neighborhood Hits	21
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.054817 (rank : 334)
Query Neighborhood Hits	426	Target Neighborhood Hits	589	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

FINC_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.103331 (rank : 277)
Query Neighborhood Hits	426	Target Neighborhood Hits	302	Shared Neighborhood Hits	23
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.101994 (rank : 278)
Query Neighborhood Hits	426	Target Neighborhood Hits	309	Shared Neighborhood Hits	25
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FNDC3_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.093473 (rank : 283)
Query Neighborhood Hits	426	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.087300 (rank : 285)
Query Neighborhood Hits	426	Target Neighborhood Hits	207	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ITB4_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.057758 (rank : 320)
Query Neighborhood Hits	426	Target Neighborhood Hits	458	Shared Neighborhood Hits	21
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KGUA_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.130932 (rank : 263)
Query Neighborhood Hits	426	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.131543 (rank : 262)
Query Neighborhood Hits	426	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

L1CAM_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.055207 (rank : 330)
Query Neighborhood Hits	426	Target Neighborhood Hits	457	Shared Neighborhood Hits	17
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.055656 (rank : 329)
Query Neighborhood Hits	426	Target Neighborhood Hits	457	Shared Neighborhood Hits	22
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LMO7_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.055020 (rank : 331)
Query Neighborhood Hits	426	Target Neighborhood Hits	507	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MAMC1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.050029 (rank : 349)
Query Neighborhood Hits	426	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC2_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.067004 (rank : 307)
Query Neighborhood Hits	426	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.069927 (rank : 301)
Query Neighborhood Hits	426	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MDGA1_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.052306 (rank : 341)
Query Neighborhood Hits	426	Target Neighborhood Hits	358	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MYOM1_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.051580 (rank : 345)
Query Neighborhood Hits	426	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NEO1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.071619 (rank : 300)
Query Neighborhood Hits	426	Target Neighborhood Hits	530	Shared Neighborhood Hits	26
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.073871 (rank : 298)
Query Neighborhood Hits	426	Target Neighborhood Hits	523	Shared Neighborhood Hits	25
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NRCAM_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.053016 (rank : 339)
Query Neighborhood Hits	426	Target Neighborhood Hits	439	Shared Neighborhood Hits	16
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.054853 (rank : 333)
Query Neighborhood Hits	426	Target Neighborhood Hits	432	Shared Neighborhood Hits	18
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PDC6I_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.051249 (rank : 348)
Query Neighborhood Hits	426	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDLI1_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.127012 (rank : 265)
Query Neighborhood Hits	426	Target Neighborhood Hits	242	Shared Neighborhood Hits	98
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.130272 (rank : 264)
Query Neighborhood Hits	426	Target Neighborhood Hits	213	Shared Neighborhood Hits	100
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI7_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.092239 (rank : 284)
Query Neighborhood Hits	426	Target Neighborhood Hits	279	Shared Neighborhood Hits	97
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD8_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.056390 (rank : 326)
Query Neighborhood Hits	426	Target Neighborhood Hits	185	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PRAX_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.058433 (rank : 319)
Query Neighborhood Hits	426	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PTEN_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.069559 (rank : 302)
Query Neighborhood Hits	426	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.069557 (rank : 303)
Query Neighborhood Hits	426	Target Neighborhood Hits	73	Shared Neighborhood Hits	41
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

RES18_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.053973 (rank : 337)
Query Neighborhood Hits	426	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

RHPN2_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.051918 (rank : 343)
Query Neighborhood Hits	426	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RHPN2_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.074169 (rank : 297)
Query Neighborhood Hits	426	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

SDK1_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.060300 (rank : 314)
Query Neighborhood Hits	426	Target Neighborhood Hits	511	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.061342 (rank : 312)
Query Neighborhood Hits	426	Target Neighborhood Hits	495	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.061337 (rank : 313)
Query Neighborhood Hits	426	Target Neighborhood Hits	495	Shared Neighborhood Hits	23
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.064044 (rank : 309)
Query Neighborhood Hits	426	Target Neighborhood Hits	480	Shared Neighborhood Hits	25
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TARSH_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.056295 (rank : 327)
Query Neighborhood Hits	426	Target Neighborhood Hits	768	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TENN_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.059116 (rank : 318)
Query Neighborhood Hits	426	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.069345 (rank : 304)
Query Neighborhood Hits	426	Target Neighborhood Hits	484	Shared Neighborhood Hits	22
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.057658 (rank : 322)
Query Neighborhood Hits	426	Target Neighborhood Hits	526	Shared Neighborhood Hits	22
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.057370 (rank : 323)
Query Neighborhood Hits	426	Target Neighborhood Hits	531	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

USH2A_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.062665 (rank : 310)
Query Neighborhood Hits	426	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.059212 (rank : 317)
Query Neighborhood Hits	426	Target Neighborhood Hits	626	Shared Neighborhood Hits	24
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

Hits sorted by NC score

PTN13_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	426	Target Neighborhood Hits	426	Shared Neighborhood Hits	426
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.990296 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	426	Target Neighborhood Hits	471	Shared Neighborhood Hits	314
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN3_HUMAN
NC score	0.875964 (rank : 3)	θ value	2.1121e-49 (rank : 3)
Query Neighborhood Hits	426	Target Neighborhood Hits	258	Shared Neighborhood Hits	219
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
NC score	0.871849 (rank : 4)	θ value	9.81109e-47 (rank : 5)
Query Neighborhood Hits	426	Target Neighborhood Hits	303	Shared Neighborhood Hits	228
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN21_MOUSE
NC score	0.814867 (rank : 5)	θ value	4.122e-45 (rank : 11)
Query Neighborhood Hits	426	Target Neighborhood Hits	155	Shared Neighborhood Hits	107
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.814652 (rank : 6)	θ value	3.48949e-44 (rank : 13)
Query Neighborhood Hits	426	Target Neighborhood Hits	143	Shared Neighborhood Hits	106
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.814627 (rank : 7)	θ value	1.32601e-43 (rank : 16)
Query Neighborhood Hits	426	Target Neighborhood Hits	142	Shared Neighborhood Hits	110
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.814564 (rank : 8)	θ value	3.48949e-44 (rank : 12)
Query Neighborhood Hits	426	Target Neighborhood Hits	163	Shared Neighborhood Hits	116
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN2_MOUSE
NC score	0.727314 (rank : 9)	θ value	1.46607e-42 (rank : 17)
Query Neighborhood Hits	426	Target Neighborhood Hits	107	Shared Neighborhood Hits	66
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.727006 (rank : 10)	θ value	3.37985e-39 (rank : 34)
Query Neighborhood Hits	426	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN2_HUMAN
NC score	0.726727 (rank : 11)	θ value	1.62093e-41 (rank : 24)
Query Neighborhood Hits	426	Target Neighborhood Hits	92	Shared Neighborhood Hits	66
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN1_HUMAN
NC score	0.726536 (rank : 12)	θ value	2.58786e-39 (rank : 33)
Query Neighborhood Hits	426	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_HUMAN
NC score	0.726132 (rank : 13)	θ value	3.73686e-38 (rank : 40)
Query Neighborhood Hits	426	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN7_MOUSE
NC score	0.724404 (rank : 14)	θ value	9.83387e-39 (rank : 38)
Query Neighborhood Hits	426	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.723771 (rank : 15)	θ value	1.42001e-37 (rank : 41)
Query Neighborhood Hits	426	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN18_MOUSE
NC score	0.723443 (rank : 16)	θ value	2.26708e-35 (rank : 47)
Query Neighborhood Hits	426	Target Neighborhood Hits	134	Shared Neighborhood Hits	75
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN12_HUMAN
NC score	0.719634 (rank : 17)	θ value	1.79215e-40 (rank : 27)
Query Neighborhood Hits	426	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
NC score	0.718981 (rank : 18)	θ value	6.81017e-40 (rank : 30)
Query Neighborhood Hits	426	Target Neighborhood Hits	123	Shared Neighborhood Hits	70
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN22_HUMAN
NC score	0.717737 (rank : 19)	θ value	9.20422e-37 (rank : 42)
Query Neighborhood Hits	426	Target Neighborhood Hits	109	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN5_HUMAN
NC score	0.714081 (rank : 20)	θ value	1.52067e-31 (rank : 61)
Query Neighborhood Hits	426	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
NC score	0.714035 (rank : 21)	θ value	7.54701e-31 (rank : 64)
Query Neighborhood Hits	426	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRO_HUMAN
NC score	0.713695 (rank : 22)	θ value	4.41421e-39 (rank : 35)
Query Neighborhood Hits	426	Target Neighborhood Hits	139	Shared Neighborhood Hits	72
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
NC score	0.713190 (rank : 23)	θ value	3.86705e-35 (rank : 49)
Query Neighborhood Hits	426	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTN22_MOUSE
NC score	0.713131 (rank : 24)	θ value	1.01765e-35 (rank : 44)
Query Neighborhood Hits	426	Target Neighborhood Hits	179	Shared Neighborhood Hits	76
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPRR_MOUSE
NC score	0.711735 (rank : 25)	θ value	2.77131e-33 (rank : 58)
Query Neighborhood Hits	426	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPR2_HUMAN
NC score	0.710114 (rank : 26)	θ value	5.0505e-35 (rank : 50)
Query Neighborhood Hits	426	Target Neighborhood Hits	103	Shared Neighborhood Hits	68
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
NC score	0.708862 (rank : 27)	θ value	1.73584e-35 (rank : 46)
Query Neighborhood Hits	426	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTN9_MOUSE
NC score	0.708597 (rank : 28)	θ value	1.9192e-34 (rank : 53)
Query Neighborhood Hits	426	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

CD45_MOUSE
NC score	0.708554 (rank : 29)	θ value	5.76516e-39 (rank : 37)
Query Neighborhood Hits	426	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTN9_HUMAN
NC score	0.708472 (rank : 30)	θ value	8.61488e-35 (rank : 51)
Query Neighborhood Hits	426	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRE_HUMAN
NC score	0.707592 (rank : 31)	θ value	6.81017e-40 (rank : 31)
Query Neighborhood Hits	426	Target Neighborhood Hits	92	Shared Neighborhood Hits	71
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
NC score	0.707529 (rank : 32)	θ value	6.81017e-40 (rank : 32)
Query Neighborhood Hits	426	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.706605 (rank : 33)	θ value	5.21438e-40 (rank : 29)
Query Neighborhood Hits	426	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRN_HUMAN
NC score	0.706422 (rank : 34)	θ value	1.01765e-35 (rank : 45)
Query Neighborhood Hits	426	Target Neighborhood Hits	156	Shared Neighborhood Hits	71
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRA_MOUSE
NC score	0.704417 (rank : 35)	θ value	2.26708e-35 (rank : 48)
Query Neighborhood Hits	426	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRN_MOUSE
NC score	0.703825 (rank : 36)	θ value	4.568e-36 (rank : 43)
Query Neighborhood Hits	426	Target Neighborhood Hits	240	Shared Neighborhood Hits	74
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

CD45_HUMAN
NC score	0.703304 (rank : 37)	θ value	5.76516e-39 (rank : 36)
Query Neighborhood Hits	426	Target Neighborhood Hits	243	Shared Neighborhood Hits	73
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRJ_MOUSE
NC score	0.693577 (rank : 38)	θ value	3.26607e-42 (rank : 22)
Query Neighborhood Hits	426	Target Neighborhood Hits	188	Shared Neighborhood Hits	74
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRJ_HUMAN
NC score	0.690468 (rank : 39)	θ value	2.50074e-42 (rank : 19)
Query Neighborhood Hits	426	Target Neighborhood Hits	207	Shared Neighborhood Hits	77
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN6_HUMAN
NC score	0.685810 (rank : 40)	θ value	1.67352e-46 (rank : 6)
Query Neighborhood Hits	426	Target Neighborhood Hits	234	Shared Neighborhood Hits	72
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTPRV_MOUSE
NC score	0.684185 (rank : 41)	θ value	1.6774e-38 (rank : 39)
Query Neighborhood Hits	426	Target Neighborhood Hits	179	Shared Neighborhood Hits	69
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN6_MOUSE
NC score	0.684021 (rank : 42)	θ value	2.58187e-47 (rank : 4)
Query Neighborhood Hits	426	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN11_MOUSE
NC score	0.667860 (rank : 43)	θ value	2.41655e-45 (rank : 9)
Query Neighborhood Hits	426	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.667848 (rank : 44)	θ value	2.41655e-45 (rank : 8)
Query Neighborhood Hits	426	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTPRB_HUMAN
NC score	0.666562 (rank : 45)	θ value	2.41655e-45 (rank : 10)
Query Neighborhood Hits	426	Target Neighborhood Hits	242	Shared Neighborhood Hits	75
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRK_HUMAN
NC score	0.661885 (rank : 46)	θ value	4.2656e-42 (rank : 23)
Query Neighborhood Hits	426	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
NC score	0.660582 (rank : 47)	θ value	1.46607e-42 (rank : 18)
Query Neighborhood Hits	426	Target Neighborhood Hits	223	Shared Neighborhood Hits	68
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRT_HUMAN
NC score	0.657205 (rank : 48)	θ value	2.50074e-42 (rank : 20)
Query Neighborhood Hits	426	Target Neighborhood Hits	217	Shared Neighborhood Hits	70
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.657174 (rank : 49)	θ value	2.50074e-42 (rank : 21)
Query Neighborhood Hits	426	Target Neighborhood Hits	219	Shared Neighborhood Hits	68
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
NC score	0.648405 (rank : 50)	θ value	2.77131e-33 (rank : 59)
Query Neighborhood Hits	426	Target Neighborhood Hits	237	Shared Neighborhood Hits	69
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_MOUSE
NC score	0.646422 (rank : 51)	θ value	6.15952e-41 (rank : 26)
Query Neighborhood Hits	426	Target Neighborhood Hits	238	Shared Neighborhood Hits	71
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.645025 (rank : 52)	θ value	2.76489e-41 (rank : 25)
Query Neighborhood Hits	426	Target Neighborhood Hits	244	Shared Neighborhood Hits	71
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRZ_HUMAN
NC score	0.636306 (rank : 53)	θ value	2.50655e-34 (rank : 54)
Query Neighborhood Hits	426	Target Neighborhood Hits	255	Shared Neighborhood Hits	71
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_HUMAN
NC score	0.635329 (rank : 54)	θ value	1.46948e-34 (rank : 52)
Query Neighborhood Hits	426	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
NC score	0.633257 (rank : 55)	θ value	2.77131e-33 (rank : 57)
Query Neighborhood Hits	426	Target Neighborhood Hits	260	Shared Neighborhood Hits	75
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTN23_MOUSE
NC score	0.626118 (rank : 56)	θ value	2.19584e-30 (rank : 65)
Query Neighborhood Hits	426	Target Neighborhood Hits	726	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN23_HUMAN
NC score	0.624727 (rank : 57)	θ value	8.91499e-32 (rank : 60)
Query Neighborhood Hits	426	Target Neighborhood Hits	646	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRS_HUMAN
NC score	0.514796 (rank : 58)	θ value	4.55743e-44 (rank : 15)
Query Neighborhood Hits	426	Target Neighborhood Hits	472	Shared Neighborhood Hits	77
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRD_HUMAN
NC score	0.505158 (rank : 59)	θ value	3.48949e-44 (rank : 14)
Query Neighborhood Hits	426	Target Neighborhood Hits	485	Shared Neighborhood Hits	77
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.502882 (rank : 60)	θ value	1.41672e-45 (rank : 7)
Query Neighborhood Hits	426	Target Neighborhood Hits	489	Shared Neighborhood Hits	75
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

E41LA_HUMAN
NC score	0.498954 (rank : 61)	θ value	8.63488e-27 (rank : 74)
Query Neighborhood Hits	426	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.498791 (rank : 62)	θ value	5.06226e-27 (rank : 73)
Query Neighborhood Hits	426	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

PTPRD_MOUSE
NC score	0.496588 (rank : 63)	θ value	1.79215e-40 (rank : 28)
Query Neighborhood Hits	426	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SYJ2B_HUMAN
NC score	0.484702 (rank : 64)	θ value	5.08577e-11 (rank : 130)
Query Neighborhood Hits	426	Target Neighborhood Hits	162	Shared Neighborhood Hits	157
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

E41LB_MOUSE
NC score	0.484088 (rank : 65)	θ value	2.69047e-20 (rank : 90)
Query Neighborhood Hits	426	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FRMD5_MOUSE
NC score	0.483429 (rank : 66)	θ value	9.56915e-18 (rank : 102)
Query Neighborhood Hits	426	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L5_HUMAN
NC score	0.483267 (rank : 67)	θ value	1.33526e-19 (rank : 92)
Query Neighborhood Hits	426	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

FRMD5_HUMAN
NC score	0.481841 (rank : 68)	θ value	1.058e-16 (rank : 111)
Query Neighborhood Hits	426	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L3_HUMAN
NC score	0.481767 (rank : 69)	θ value	1.24688e-25 (rank : 77)
Query Neighborhood Hits	426	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

41_HUMAN
NC score	0.481100 (rank : 70)	θ value	7.30988e-26 (rank : 75)
Query Neighborhood Hits	426	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L1_MOUSE
NC score	0.480860 (rank : 71)	θ value	1.80048e-24 (rank : 84)
Query Neighborhood Hits	426	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
NC score	0.478903 (rank : 72)	θ value	8.08199e-25 (rank : 82)
Query Neighborhood Hits	426	Target Neighborhood Hits	180	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

FRMD6_MOUSE
NC score	0.478517 (rank : 73)	θ value	3.74554e-30 (rank : 66)
Query Neighborhood Hits	426	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

E41LB_HUMAN
NC score	0.477845 (rank : 74)	θ value	5.07402e-19 (rank : 95)
Query Neighborhood Hits	426	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

41_MOUSE
NC score	0.477748 (rank : 75)	θ value	1.99067e-23 (rank : 88)
Query Neighborhood Hits	426	Target Neighborhood Hits	184	Shared Neighborhood Hits	56
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

FRMD1_HUMAN
NC score	0.476552 (rank : 76)	θ value	9.2256e-29 (rank : 69)
Query Neighborhood Hits	426	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

MPDZ_MOUSE
NC score	0.476514 (rank : 77)	θ value	6.18819e-25 (rank : 81)
Query Neighborhood Hits	426	Target Neighborhood Hits	298	Shared Neighborhood Hits	193
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPDZ_HUMAN
NC score	0.475295 (rank : 78)	θ value	7.30988e-26 (rank : 76)
Query Neighborhood Hits	426	Target Neighborhood Hits	261	Shared Neighborhood Hits	191
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

E41L2_HUMAN
NC score	0.473839 (rank : 79)	θ value	6.18819e-25 (rank : 80)
Query Neighborhood Hits	426	Target Neighborhood Hits	287	Shared Neighborhood Hits	61
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L3_MOUSE
NC score	0.473593 (rank : 80)	θ value	2.12685e-25 (rank : 78)
Query Neighborhood Hits	426	Target Neighborhood Hits	250	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

FRMD6_HUMAN
NC score	0.473438 (rank : 81)	θ value	4.57862e-28 (rank : 72)
Query Neighborhood Hits	426	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

INADL_MOUSE
NC score	0.473363 (rank : 82)	θ value	1.80048e-24 (rank : 85)
Query Neighborhood Hits	426	Target Neighborhood Hits	290	Shared Neighborhood Hits	194
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

INADL_HUMAN
NC score	0.470794 (rank : 83)	θ value	1.05554e-24 (rank : 83)
Query Neighborhood Hits	426	Target Neighborhood Hits	260	Shared Neighborhood Hits	190
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

E41L2_MOUSE
NC score	0.459557 (rank : 84)	θ value	5.23862e-24 (rank : 87)
Query Neighborhood Hits	426	Target Neighborhood Hits	459	Shared Neighborhood Hits	77
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MERL_HUMAN
NC score	0.458151 (rank : 85)	θ value	5.584e-34 (rank : 56)
Query Neighborhood Hits	426	Target Neighborhood Hits	532	Shared Neighborhood Hits	72
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
NC score	0.457779 (rank : 86)	θ value	4.27553e-34 (rank : 55)
Query Neighborhood Hits	426	Target Neighborhood Hits	524	Shared Neighborhood Hits	71
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

FRM4B_HUMAN
NC score	0.452752 (rank : 87)	θ value	1.058e-16 (rank : 110)
Query Neighborhood Hits	426	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.452163 (rank : 88)	θ value	3.63628e-17 (rank : 106)
Query Neighborhood Hits	426	Target Neighborhood Hits	109	Shared Neighborhood Hits	50
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_HUMAN
NC score	0.450834 (rank : 89)	θ value	1.74391e-19 (rank : 93)
Query Neighborhood Hits	426	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

LIN7B_HUMAN
NC score	0.450059 (rank : 90)	θ value	5.08577e-11 (rank : 129)
Query Neighborhood Hits	426	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7C_HUMAN
NC score	0.450025 (rank : 91)	θ value	1.133e-10 (rank : 134)
Query Neighborhood Hits	426	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.450025 (rank : 92)	θ value	1.133e-10 (rank : 135)
Query Neighborhood Hits	426	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

FRM4A_MOUSE
NC score	0.449995 (rank : 93)	θ value	1.02238e-19 (rank : 91)
Query Neighborhood Hits	426	Target Neighborhood Hits	108	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

LIN7B_MOUSE
NC score	0.449016 (rank : 94)	θ value	6.64225e-11 (rank : 131)
Query Neighborhood Hits	426	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

PAR3L_HUMAN
NC score	0.447929 (rank : 95)	θ value	1.86753e-13 (rank : 120)
Query Neighborhood Hits	426	Target Neighborhood Hits	297	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

LIN7A_HUMAN
NC score	0.446407 (rank : 96)	θ value	2.28291e-11 (rank : 126)
Query Neighborhood Hits	426	Target Neighborhood Hits	193	Shared Neighborhood Hits	181
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.446366 (rank : 97)	θ value	2.28291e-11 (rank : 127)
Query Neighborhood Hits	426	Target Neighborhood Hits	193	Shared Neighborhood Hits	181
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

PARD3_HUMAN
NC score	0.444261 (rank : 98)	θ value	1.92812e-18 (rank : 97)
Query Neighborhood Hits	426	Target Neighborhood Hits	312	Shared Neighborhood Hits	171
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
NC score	0.442625 (rank : 99)	θ value	3.88503e-19 (rank : 94)
Query Neighborhood Hits	426	Target Neighborhood Hits	290	Shared Neighborhood Hits	171
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

MYLIP_MOUSE
NC score	0.442291 (rank : 100)	θ value	6.64225e-11 (rank : 132)
Query Neighborhood Hits	426	Target Neighborhood Hits	139	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.432051 (rank : 101)	θ value	4.30538e-10 (rank : 139)
Query Neighborhood Hits	426	Target Neighborhood Hits	162	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

EZRI_HUMAN
NC score	0.429728 (rank : 102)	θ value	2.05525e-28 (rank : 70)
Query Neighborhood Hits	426	Target Neighborhood Hits	663	Shared Neighborhood Hits	74
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PDZD7_HUMAN
NC score	0.428627 (rank : 103)	θ value	3.41135e-07 (rank : 174)
Query Neighborhood Hits	426	Target Neighborhood Hits	181	Shared Neighborhood Hits	168
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

EZRI_MOUSE
NC score	0.428580 (rank : 104)	θ value	2.68423e-28 (rank : 71)
Query Neighborhood Hits	426	Target Neighborhood Hits	693	Shared Neighborhood Hits	75
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

DLG4_MOUSE
NC score	0.426600 (rank : 105)	θ value	2.5182e-18 (rank : 98)
Query Neighborhood Hits	426	Target Neighborhood Hits	282	Shared Neighborhood Hits	180
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.425923 (rank : 106)	θ value	1.92812e-18 (rank : 96)
Query Neighborhood Hits	426	Target Neighborhood Hits	286	Shared Neighborhood Hits	178
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_MOUSE
NC score	0.425208 (rank : 107)	θ value	6.18819e-25 (rank : 79)
Query Neighborhood Hits	426	Target Neighborhood Hits	271	Shared Neighborhood Hits	177
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PDZD2_HUMAN
NC score	0.425031 (rank : 108)	θ value	1.63225e-17 (rank : 104)
Query Neighborhood Hits	426	Target Neighborhood Hits	772	Shared Neighborhood Hits	207
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

USH1C_HUMAN
NC score	0.424932 (rank : 109)	θ value	1.06045e-08 (rank : 153)
Query Neighborhood Hits	426	Target Neighborhood Hits	327	Shared Neighborhood Hits	189
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

GRIP2_HUMAN
NC score	0.423987 (rank : 110)	θ value	4.59992e-12 (rank : 122)
Query Neighborhood Hits	426	Target Neighborhood Hits	256	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

DLG2_HUMAN
NC score	0.423828 (rank : 111)	θ value	5.23862e-24 (rank : 86)
Query Neighborhood Hits	426	Target Neighborhood Hits	279	Shared Neighborhood Hits	178
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

RADI_HUMAN
NC score	0.422465 (rank : 112)	θ value	3.3877e-31 (rank : 62)
Query Neighborhood Hits	426	Target Neighborhood Hits	741	Shared Neighborhood Hits	73
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

DLG3_MOUSE
NC score	0.420233 (rank : 113)	θ value	1.24977e-17 (rank : 103)
Query Neighborhood Hits	426	Target Neighborhood Hits	274	Shared Neighborhood Hits	178
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

IL16_HUMAN
NC score	0.420002 (rank : 114)	θ value	9.59137e-10 (rank : 143)
Query Neighborhood Hits	426	Target Neighborhood Hits	207	Shared Neighborhood Hits	146
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

RADI_MOUSE
NC score	0.419989 (rank : 115)	θ value	3.3877e-31 (rank : 63)
Query Neighborhood Hits	426	Target Neighborhood Hits	773	Shared Neighborhood Hits	74
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

DLG1_HUMAN
NC score	0.419003 (rank : 116)	θ value	5.60996e-18 (rank : 100)
Query Neighborhood Hits	426	Target Neighborhood Hits	290	Shared Neighborhood Hits	176
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG3_HUMAN
NC score	0.418772 (rank : 117)	θ value	9.56915e-18 (rank : 101)
Query Neighborhood Hits	426	Target Neighborhood Hits	269	Shared Neighborhood Hits	178
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

PDZ11_MOUSE
NC score	0.418066 (rank : 118)	θ value	1.53129e-07 (rank : 169)
Query Neighborhood Hits	426	Target Neighborhood Hits	154	Shared Neighborhood Hits	137
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

DLG1_MOUSE
NC score	0.417327 (rank : 119)	θ value	3.28887e-18 (rank : 99)
Query Neighborhood Hits	426	Target Neighborhood Hits	285	Shared Neighborhood Hits	170
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

PDZ11_HUMAN
NC score	0.417065 (rank : 120)	θ value	3.41135e-07 (rank : 173)
Query Neighborhood Hits	426	Target Neighborhood Hits	160	Shared Neighborhood Hits	144
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

WHRN_MOUSE
NC score	0.416783 (rank : 121)	θ value	8.67504e-11 (rank : 133)
Query Neighborhood Hits	426	Target Neighborhood Hits	412	Shared Neighborhood Hits	190
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

GRIP1_MOUSE
NC score	0.415141 (rank : 122)	θ value	2.20605e-14 (rank : 118)
Query Neighborhood Hits	426	Target Neighborhood Hits	241	Shared Neighborhood Hits	190
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_HUMAN
NC score	0.414630 (rank : 123)	θ value	1.74796e-11 (rank : 125)
Query Neighborhood Hits	426	Target Neighborhood Hits	231	Shared Neighborhood Hits	194
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

WHRN_HUMAN
NC score	0.414598 (rank : 124)	θ value	1.25267e-09 (rank : 145)
Query Neighborhood Hits	426	Target Neighborhood Hits	325	Shared Neighborhood Hits	191
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

LNX2_MOUSE
NC score	0.413588 (rank : 125)	θ value	7.58209e-15 (rank : 117)
Query Neighborhood Hits	426	Target Neighborhood Hits	407	Shared Neighborhood Hits	180
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MAGI1_MOUSE
NC score	0.410271 (rank : 126)	θ value	1.058e-16 (rank : 112)
Query Neighborhood Hits	426	Target Neighborhood Hits	403	Shared Neighborhood Hits	200
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

IL16_MOUSE
NC score	0.408767 (rank : 127)	θ value	6.21693e-09 (rank : 150)
Query Neighborhood Hits	426	Target Neighborhood Hits	189	Shared Neighborhood Hits	142
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

MAGI1_HUMAN
NC score	0.408211 (rank : 128)	θ value	2.88119e-14 (rank : 119)
Query Neighborhood Hits	426	Target Neighborhood Hits	388	Shared Neighborhood Hits	197
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

LNX2_HUMAN
NC score	0.408199 (rank : 129)	θ value	5.62301e-10 (rank : 141)
Query Neighborhood Hits	426	Target Neighborhood Hits	389	Shared Neighborhood Hits	178
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MAGI2_MOUSE
NC score	0.402662 (rank : 130)	θ value	6.20254e-17 (rank : 108)
Query Neighborhood Hits	426	Target Neighborhood Hits	370	Shared Neighborhood Hits	197
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

LNX1_MOUSE
NC score	0.401284 (rank : 131)	θ value	4.59992e-12 (rank : 124)
Query Neighborhood Hits	426	Target Neighborhood Hits	377	Shared Neighborhood Hits	180
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAGI2_HUMAN
NC score	0.400184 (rank : 132)	θ value	2.7842e-17 (rank : 105)
Query Neighborhood Hits	426	Target Neighborhood Hits	373	Shared Neighborhood Hits	190
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PDZD1_MOUSE
NC score	0.398529 (rank : 133)	θ value	6.21693e-09 (rank : 151)
Query Neighborhood Hits	426	Target Neighborhood Hits	191	Shared Neighborhood Hits	156
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

USH1C_MOUSE
NC score	0.398453 (rank : 134)	θ value	2.36244e-08 (rank : 158)
Query Neighborhood Hits	426	Target Neighborhood Hits	557	Shared Neighborhood Hits	197
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

MOES_HUMAN
NC score	0.396453 (rank : 135)	θ value	2.42779e-29 (rank : 68)
Query Neighborhood Hits	426	Target Neighborhood Hits	892	Shared Neighborhood Hits	79
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

LNX1_HUMAN
NC score	0.395504 (rank : 136)	θ value	2.28291e-11 (rank : 128)
Query Neighborhood Hits	426	Target Neighborhood Hits	379	Shared Neighborhood Hits	172
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

FARP1_HUMAN
NC score	0.394468 (rank : 137)	θ value	1.058e-16 (rank : 109)
Query Neighborhood Hits	426	Target Neighborhood Hits	241	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

MOES_MOUSE
NC score	0.391949 (rank : 138)	θ value	1.85889e-29 (rank : 67)
Query Neighborhood Hits	426	Target Neighborhood Hits	923	Shared Neighborhood Hits	82
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PDZD1_HUMAN
NC score	0.391250 (rank : 139)	θ value	3.64472e-09 (rank : 147)
Query Neighborhood Hits	426	Target Neighborhood Hits	190	Shared Neighborhood Hits	153
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHERF_MOUSE
NC score	0.389122 (rank : 140)	θ value	9.59137e-10 (rank : 144)
Query Neighborhood Hits	426	Target Neighborhood Hits	195	Shared Neighborhood Hits	159
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

GOPC_MOUSE
NC score	0.388497 (rank : 141)	θ value	8.97725e-08 (rank : 166)
Query Neighborhood Hits	426	Target Neighborhood Hits	323	Shared Neighborhood Hits	173
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

GOPC_HUMAN
NC score	0.383270 (rank : 142)	θ value	8.97725e-08 (rank : 165)
Query Neighborhood Hits	426	Target Neighborhood Hits	377	Shared Neighborhood Hits	174
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

FARP2_HUMAN
NC score	0.382729 (rank : 143)	θ value	4.74913e-17 (rank : 107)
Query Neighborhood Hits	426	Target Neighborhood Hits	240	Shared Neighborhood Hits	56
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.381305 (rank : 144)	θ value	1.5773e-20 (rank : 89)
Query Neighborhood Hits	426	Target Neighborhood Hits	209	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

TX1B3_HUMAN
NC score	0.378434 (rank : 145)	θ value	0.00390308 (rank : 215)
Query Neighborhood Hits	426	Target Neighborhood Hits	161	Shared Neighborhood Hits	150
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

NHRF2_HUMAN
NC score	0.377036 (rank : 146)	θ value	8.97725e-08 (rank : 167)
Query Neighborhood Hits	426	Target Neighborhood Hits	197	Shared Neighborhood Hits	165
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

ZO3_MOUSE
NC score	0.376935 (rank : 147)	θ value	2.36244e-08 (rank : 159)
Query Neighborhood Hits	426	Target Neighborhood Hits	224	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

TX1B3_MOUSE
NC score	0.375781 (rank : 148)	θ value	0.00390308 (rank : 216)
Query Neighborhood Hits	426	Target Neighborhood Hits	158	Shared Neighborhood Hits	147
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

SNTG2_HUMAN
NC score	0.375378 (rank : 149)	θ value	6.87365e-08 (rank : 163)
Query Neighborhood Hits	426	Target Neighborhood Hits	191	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

NHERF_HUMAN
NC score	0.374888 (rank : 150)	θ value	2.36244e-08 (rank : 157)
Query Neighborhood Hits	426	Target Neighborhood Hits	190	Shared Neighborhood Hits	156
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

ZO3_HUMAN
NC score	0.371842 (rank : 151)	θ value	1.53129e-07 (rank : 170)
Query Neighborhood Hits	426	Target Neighborhood Hits	219	Shared Neighborhood Hits	174
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PDZD3_HUMAN
NC score	0.366865 (rank : 152)	θ value	2.52405e-10 (rank : 136)
Query Neighborhood Hits	426	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

NHRF2_MOUSE
NC score	0.366564 (rank : 153)	θ value	1.87187e-05 (rank : 198)
Query Neighborhood Hits	426	Target Neighborhood Hits	194	Shared Neighborhood Hits	167
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

ZO1_MOUSE
NC score	0.360473 (rank : 154)	θ value	3.07829e-16 (rank : 113)
Query Neighborhood Hits	426	Target Neighborhood Hits	453	Shared Neighborhood Hits	173
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SNTB2_MOUSE
NC score	0.360385 (rank : 155)	θ value	4.45536e-07 (rank : 175)
Query Neighborhood Hits	426	Target Neighborhood Hits	181	Shared Neighborhood Hits	160
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG2_MOUSE
NC score	0.359843 (rank : 156)	θ value	5.26297e-08 (rank : 161)
Query Neighborhood Hits	426	Target Neighborhood Hits	176	Shared Neighborhood Hits	167
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTB2_HUMAN
NC score	0.358936 (rank : 157)	θ value	1.29631e-06 (rank : 182)
Query Neighborhood Hits	426	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

ZO2_HUMAN
NC score	0.358024 (rank : 158)	θ value	1.80886e-08 (rank : 155)
Query Neighborhood Hits	426	Target Neighborhood Hits	289	Shared Neighborhood Hits	179
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO1_HUMAN
NC score	0.356876 (rank : 159)	θ value	4.02038e-16 (rank : 114)
Query Neighborhood Hits	426	Target Neighborhood Hits	474	Shared Neighborhood Hits	174
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_MOUSE
NC score	0.356813 (rank : 160)	θ value	1.80886e-08 (rank : 156)
Query Neighborhood Hits	426	Target Neighborhood Hits	296	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

SNTA1_HUMAN
NC score	0.350044 (rank : 161)	θ value	6.43352e-06 (rank : 194)
Query Neighborhood Hits	426	Target Neighborhood Hits	186	Shared Neighborhood Hits	165
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTG1_MOUSE
NC score	0.349833 (rank : 162)	θ value	2.88788e-06 (rank : 187)
Query Neighborhood Hits	426	Target Neighborhood Hits	179	Shared Neighborhood Hits	171
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
NC score	0.349033 (rank : 163)	θ value	3.77169e-06 (rank : 189)
Query Neighborhood Hits	426	Target Neighborhood Hits	181	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

K1849_HUMAN
NC score	0.347967 (rank : 164)	θ value	4.59992e-12 (rank : 123)
Query Neighborhood Hits	426	Target Neighborhood Hits	220	Shared Neighborhood Hits	144
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SNTA1_MOUSE
NC score	0.344997 (rank : 165)	θ value	1.09739e-05 (rank : 196)
Query Neighborhood Hits	426	Target Neighborhood Hits	170	Shared Neighborhood Hits	159
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PDZD3_MOUSE
NC score	0.342309 (rank : 166)	θ value	3.77169e-06 (rank : 188)
Query Neighborhood Hits	426	Target Neighborhood Hits	171	Shared Neighborhood Hits	155
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PZRN4_HUMAN
NC score	0.339943 (rank : 167)	θ value	1.38499e-08 (rank : 154)
Query Neighborhood Hits	426	Target Neighborhood Hits	438	Shared Neighborhood Hits	152
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

K1849_MOUSE
NC score	0.339095 (rank : 168)	θ value	1.2105e-12 (rank : 121)
Query Neighborhood Hits	426	Target Neighborhood Hits	335	Shared Neighborhood Hits	159
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SNTB1_HUMAN
NC score	0.338912 (rank : 169)	θ value	2.44474e-05 (rank : 199)
Query Neighborhood Hits	426	Target Neighborhood Hits	157	Shared Neighborhood Hits	148
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.337922 (rank : 170)	θ value	2.44474e-05 (rank : 200)
Query Neighborhood Hits	426	Target Neighborhood Hits	160	Shared Neighborhood Hits	146
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PZRN3_MOUSE
NC score	0.332121 (rank : 171)	θ value	6.87365e-08 (rank : 162)
Query Neighborhood Hits	426	Target Neighborhood Hits	447	Shared Neighborhood Hits	153
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.332110 (rank : 172)	θ value	3.08544e-08 (rank : 160)
Query Neighborhood Hits	426	Target Neighborhood Hits	461	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

AFAD_HUMAN
NC score	0.304891 (rank : 173)	θ value	8.11959e-09 (rank : 152)
Query Neighborhood Hits	426	Target Neighborhood Hits	689	Shared Neighborhood Hits	156
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

LAP4_HUMAN
NC score	0.295338 (rank : 174)	θ value	6.85773e-16 (rank : 115)
Query Neighborhood Hits	426	Target Neighborhood Hits	608	Shared Neighborhood Hits	196
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
NC score	0.294688 (rank : 175)	θ value	1.16975e-15 (rank : 116)
Query Neighborhood Hits	426	Target Neighborhood Hits	590	Shared Neighborhood Hits	195
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

DVL3_HUMAN
NC score	0.290926 (rank : 176)	θ value	1.29631e-06 (rank : 180)
Query Neighborhood Hits	426	Target Neighborhood Hits	194	Shared Neighborhood Hits	116
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
NC score	0.290366 (rank : 177)	θ value	1.29631e-06 (rank : 181)
Query Neighborhood Hits	426	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1_HUMAN
NC score	0.289271 (rank : 178)	θ value	5.81887e-07 (rank : 176)
Query Neighborhood Hits	426	Target Neighborhood Hits	158	Shared Neighborhood Hits	119
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

NEB1_HUMAN
NC score	0.289213 (rank : 179)	θ value	3.29651e-10 (rank : 137)
Query Neighborhood Hits	426	Target Neighborhood Hits	829	Shared Neighborhood Hits	157
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

DVL1_MOUSE
NC score	0.287905 (rank : 180)	θ value	7.59969e-07 (rank : 178)
Query Neighborhood Hits	426	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1L_HUMAN
NC score	0.279699 (rank : 181)	θ value	1.69304e-06 (rank : 183)
Query Neighborhood Hits	426	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL2_HUMAN
NC score	0.279687 (rank : 182)	θ value	4.92598e-06 (rank : 190)
Query Neighborhood Hits	426	Target Neighborhood Hits	223	Shared Neighborhood Hits	117
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.279514 (rank : 183)	θ value	4.92598e-06 (rank : 191)
Query Neighborhood Hits	426	Target Neighborhood Hits	233	Shared Neighborhood Hits	119
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

NEB2_HUMAN
NC score	0.279012 (rank : 184)	θ value	4.76016e-09 (rank : 148)
Query Neighborhood Hits	426	Target Neighborhood Hits	883	Shared Neighborhood Hits	147
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.274189 (rank : 185)	θ value	4.76016e-09 (rank : 149)
Query Neighborhood Hits	426	Target Neighborhood Hits	889	Shared Neighborhood Hits	150
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

GRASP_HUMAN
NC score	0.271260 (rank : 186)	θ value	5.81887e-07 (rank : 177)
Query Neighborhood Hits	426	Target Neighborhood Hits	147	Shared Neighborhood Hits	117
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.267541 (rank : 187)	θ value	1.69304e-06 (rank : 184)
Query Neighborhood Hits	426	Target Neighborhood Hits	131	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

STXB4_HUMAN
NC score	0.266907 (rank : 188)	θ value	2.61198e-07 (rank : 172)
Query Neighborhood Hits	426	Target Neighborhood Hits	616	Shared Neighborhood Hits	120
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

MPP4_HUMAN
NC score	0.264435 (rank : 189)	θ value	0.00175202 (rank : 210)
Query Neighborhood Hits	426	Target Neighborhood Hits	205	Shared Neighborhood Hits	139
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDZK4_MOUSE
NC score	0.264212 (rank : 190)	θ value	0.00134147 (rank : 208)
Query Neighborhood Hits	426	Target Neighborhood Hits	165	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_HUMAN
NC score	0.263971 (rank : 191)	θ value	0.000602161 (rank : 205)
Query Neighborhood Hits	426	Target Neighborhood Hits	165	Shared Neighborhood Hits	118
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

DLG5_HUMAN
NC score	0.262490 (rank : 192)	θ value	2.61198e-07 (rank : 171)
Query Neighborhood Hits	426	Target Neighborhood Hits	1088	Shared Neighborhood Hits	194
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

STXB4_MOUSE
NC score	0.256538 (rank : 193)	θ value	9.92553e-07 (rank : 179)
Query Neighborhood Hits	426	Target Neighborhood Hits	629	Shared Neighborhood Hits	113
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TLN1_HUMAN
NC score	0.255199 (rank : 194)	θ value	3.29651e-10 (rank : 138)
Query Neighborhood Hits	426	Target Neighborhood Hits	218	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.254710 (rank : 195)	θ value	1.17247e-07 (rank : 168)
Query Neighborhood Hits	426	Target Neighborhood Hits	149	Shared Neighborhood Hits	57
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_MOUSE
NC score	0.253647 (rank : 196)	θ value	7.34386e-10 (rank : 142)
Query Neighborhood Hits	426	Target Neighborhood Hits	213	Shared Neighborhood Hits	50
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
NC score	0.250974 (rank : 197)	θ value	6.87365e-08 (rank : 164)
Query Neighborhood Hits	426	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

MPP5_HUMAN
NC score	0.250778 (rank : 198)	θ value	0.00509761 (rank : 217)
Query Neighborhood Hits	426	Target Neighborhood Hits	231	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.250280 (rank : 199)	θ value	0.00509761 (rank : 218)
Query Neighborhood Hits	426	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PICK1_MOUSE
NC score	0.250169 (rank : 200)	θ value	0.0113563 (rank : 230)
Query Neighborhood Hits	426	Target Neighborhood Hits	131	Shared Neighborhood Hits	121
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
NC score	0.249943 (rank : 201)	θ value	0.0148317 (rank : 231)
Query Neighborhood Hits	426	Target Neighborhood Hits	132	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

APBA1_HUMAN
NC score	0.249026 (rank : 202)	θ value	0.00665767 (rank : 221)
Query Neighborhood Hits	426	Target Neighborhood Hits	325	Shared Neighborhood Hits	156
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

APBA2_MOUSE
NC score	0.242628 (rank : 203)	θ value	0.00134147 (rank : 207)
Query Neighborhood Hits	426	Target Neighborhood Hits	219	Shared Neighborhood Hits	150
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.242164 (rank : 204)	θ value	0.00134147 (rank : 206)
Query Neighborhood Hits	426	Target Neighborhood Hits	220	Shared Neighborhood Hits	151
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

MPP4_MOUSE
NC score	0.239835 (rank : 205)	θ value	0.00665767 (rank : 223)
Query Neighborhood Hits	426	Target Neighborhood Hits	188	Shared Neighborhood Hits	121
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP3_MOUSE
NC score	0.239587 (rank : 206)	θ value	0.0736092 (rank : 245)
Query Neighborhood Hits	426	Target Neighborhood Hits	165	Shared Neighborhood Hits	133
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

PAR6G_HUMAN
NC score	0.238953 (rank : 207)	θ value	0.00509761 (rank : 219)
Query Neighborhood Hits	426	Target Neighborhood Hits	159	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
NC score	0.238887 (rank : 208)	θ value	0.00509761 (rank : 220)
Query Neighborhood Hits	426	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

MPP3_HUMAN
NC score	0.237934 (rank : 209)	θ value	0.0563607 (rank : 243)
Query Neighborhood Hits	426	Target Neighborhood Hits	171	Shared Neighborhood Hits	134
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

APBA3_HUMAN
NC score	0.236177 (rank : 210)	θ value	0.00665767 (rank : 222)
Query Neighborhood Hits	426	Target Neighborhood Hits	201	Shared Neighborhood Hits	139
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6B_HUMAN
NC score	0.234990 (rank : 211)	θ value	0.0113563 (rank : 228)
Query Neighborhood Hits	426	Target Neighborhood Hits	126	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
NC score	0.234658 (rank : 212)	θ value	0.0113563 (rank : 229)
Query Neighborhood Hits	426	Target Neighborhood Hits	128	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

RHPN1_MOUSE
NC score	0.229577 (rank : 213)	θ value	0.0252991 (rank : 237)
Query Neighborhood Hits	426	Target Neighborhood Hits	154	Shared Neighborhood Hits	129
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PDLI2_HUMAN
NC score	0.228403 (rank : 214)	θ value	0.00228821 (rank : 211)
Query Neighborhood Hits	426	Target Neighborhood Hits	245	Shared Neighborhood Hits	128
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

RPGF6_HUMAN
NC score	0.227538 (rank : 215)	θ value	0.00035302 (rank : 204)
Query Neighborhood Hits	426	Target Neighborhood Hits	266	Shared Neighborhood Hits	155
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

DUS23_MOUSE
NC score	0.224987 (rank : 216)	θ value	2.36792 (rank : 325)
Query Neighborhood Hits	426	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PAR6A_MOUSE
NC score	0.224604 (rank : 217)	θ value	0.0252991 (rank : 233)
Query Neighborhood Hits	426	Target Neighborhood Hits	115	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6A_HUMAN
NC score	0.223656 (rank : 218)	θ value	0.0252991 (rank : 232)
Query Neighborhood Hits	426	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

SDCB1_MOUSE
NC score	0.223120 (rank : 219)	θ value	0.279714 (rank : 270)
Query Neighborhood Hits	426	Target Neighborhood Hits	144	Shared Neighborhood Hits	135
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB1_HUMAN
NC score	0.222786 (rank : 220)	θ value	0.279714 (rank : 269)
Query Neighborhood Hits	426	Target Neighborhood Hits	150	Shared Neighborhood Hits	142
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

APBA3_MOUSE
NC score	0.221300 (rank : 221)	θ value	0.0431538 (rank : 238)
Query Neighborhood Hits	426	Target Neighborhood Hits	174	Shared Neighborhood Hits	133
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PSCBP_MOUSE
NC score	0.220931 (rank : 222)	θ value	0.0961366 (rank : 249)
Query Neighborhood Hits	426	Target Neighborhood Hits	118	Shared Neighborhood Hits	111
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

DUS23_HUMAN
NC score	0.218196 (rank : 223)	θ value	1.81305 (rank : 316)
Query Neighborhood Hits	426	Target Neighborhood Hits	98	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

NOS1_HUMAN
NC score	0.216658 (rank : 224)	θ value	4.30538e-10 (rank : 140)
Query Neighborhood Hits	426	Target Neighborhood Hits	218	Shared Neighborhood Hits	142
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

RHPN1_HUMAN
NC score	0.213292 (rank : 225)	θ value	0.279714 (rank : 268)
Query Neighborhood Hits	426	Target Neighborhood Hits	158	Shared Neighborhood Hits	123
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PDLI2_MOUSE
NC score	0.209982 (rank : 226)	θ value	0.0252991 (rank : 234)
Query Neighborhood Hits	426	Target Neighborhood Hits	220	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

EM55_HUMAN
NC score	0.207899 (rank : 227)	θ value	0.365318 (rank : 272)
Query Neighborhood Hits	426	Target Neighborhood Hits	228	Shared Neighborhood Hits	128
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.206533 (rank : 228)	θ value	0.62314 (rank : 287)
Query Neighborhood Hits	426	Target Neighborhood Hits	221	Shared Neighborhood Hits	126
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

PSCBP_HUMAN
NC score	0.205889 (rank : 229)	θ value	0.279714 (rank : 267)
Query Neighborhood Hits	426	Target Neighborhood Hits	123	Shared Neighborhood Hits	112
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

ARHGB_HUMAN
NC score	0.199648 (rank : 230)	θ value	0.00298849 (rank : 212)
Query Neighborhood Hits	426	Target Neighborhood Hits	375	Shared Neighborhood Hits	161
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

NOS1_MOUSE
NC score	0.193931 (rank : 231)	θ value	3.64472e-09 (rank : 146)
Query Neighborhood Hits	426	Target Neighborhood Hits	155	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

ARHGC_HUMAN
NC score	0.191748 (rank : 232)	θ value	0.00020696 (rank : 203)
Query Neighborhood Hits	426	Target Neighborhood Hits	351	Shared Neighborhood Hits	149
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.191702 (rank : 233)	θ value	9.29e-05 (rank : 201)
Query Neighborhood Hits	426	Target Neighborhood Hits	344	Shared Neighborhood Hits	153
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SDCB2_HUMAN
NC score	0.190444 (rank : 234)	θ value	0.0563607 (rank : 244)
Query Neighborhood Hits	426	Target Neighborhood Hits	121	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

RPGF2_HUMAN
NC score	0.190329 (rank : 235)	θ value	0.00869519 (rank : 225)
Query Neighborhood Hits	426	Target Neighborhood Hits	242	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SDCB2_MOUSE
NC score	0.189077 (rank : 236)	θ value	0.62314 (rank : 292)
Query Neighborhood Hits	426	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

MPP2_HUMAN
NC score	0.188296 (rank : 237)	θ value	0.00175202 (rank : 209)
Query Neighborhood Hits	426	Target Neighborhood Hits	173	Shared Neighborhood Hits	93
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
NC score	0.188180 (rank : 238)	θ value	0.00390308 (rank : 213)
Query Neighborhood Hits	426	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

SYP2L_HUMAN
NC score	0.188111 (rank : 239)	θ value	0.47712 (rank : 283)
Query Neighborhood Hits	426	Target Neighborhood Hits	400	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

MPP6_MOUSE
NC score	0.178778 (rank : 240)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	426	Target Neighborhood Hits	187	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP6_HUMAN
NC score	0.176376 (rank : 241)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	426	Target Neighborhood Hits	180	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

SYNP2_MOUSE
NC score	0.172480 (rank : 242)	θ value	0.0961366 (rank : 250)
Query Neighborhood Hits	426	Target Neighborhood Hits	252	Shared Neighborhood Hits	120
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

RGS12_HUMAN
NC score	0.171416 (rank : 243)	θ value	0.0252991 (rank : 236)
Query Neighborhood Hits	426	Target Neighborhood Hits	333	Shared Neighborhood Hits	136
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RIMS1_HUMAN
NC score	0.165887 (rank : 244)	θ value	0.000121331 (rank : 202)
Query Neighborhood Hits	426	Target Neighborhood Hits	437	Shared Neighborhood Hits	139
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

LRRC7_HUMAN
NC score	0.160864 (rank : 245)	θ value	4.92598e-06 (rank : 192)
Query Neighborhood Hits	426	Target Neighborhood Hits	423	Shared Neighborhood Hits	115
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.160054 (rank : 246)	θ value	4.92598e-06 (rank : 193)
Query Neighborhood Hits	426	Target Neighborhood Hits	416	Shared Neighborhood Hits	115
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

APXL_HUMAN
NC score	0.155059 (rank : 247)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	426	Target Neighborhood Hits	553	Shared Neighborhood Hits	110
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

LAP2_HUMAN
NC score	0.151635 (rank : 248)	θ value	8.40245e-06 (rank : 195)
Query Neighborhood Hits	426	Target Neighborhood Hits	499	Shared Neighborhood Hits	112
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

RIMS2_HUMAN
NC score	0.150115 (rank : 249)	θ value	2.21117e-06 (rank : 185)
Query Neighborhood Hits	426	Target Neighborhood Hits	342	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.149683 (rank : 250)	θ value	2.21117e-06 (rank : 186)
Query Neighborhood Hits	426	Target Neighborhood Hits	376	Shared Neighborhood Hits	114
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SHAN2_HUMAN
NC score	0.148677 (rank : 251)	θ value	4.03905 (rank : 358)
Query Neighborhood Hits	426	Target Neighborhood Hits	346	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PDLI4_MOUSE
NC score	0.148162 (rank : 252)	θ value	0.0252991 (rank : 235)
Query Neighborhood Hits	426	Target Neighborhood Hits	233	Shared Neighborhood Hits	109
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI3_HUMAN
NC score	0.147877 (rank : 253)	θ value	1.81305 (rank : 321)
Query Neighborhood Hits	426	Target Neighborhood Hits	199	Shared Neighborhood Hits	105
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

GIPC1_MOUSE
NC score	0.145837 (rank : 254)	θ value	0.365318 (rank : 273)
Query Neighborhood Hits	426	Target Neighborhood Hits	92	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

LAP2_MOUSE
NC score	0.144944 (rank : 255)	θ value	1.43324e-05 (rank : 197)
Query Neighborhood Hits	426	Target Neighborhood Hits	482	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDLI4_HUMAN
NC score	0.143936 (rank : 256)	θ value	0.125558 (rank : 254)
Query Neighborhood Hits	426	Target Neighborhood Hits	245	Shared Neighborhood Hits	106
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

GIPC1_HUMAN
NC score	0.140562 (rank : 257)	θ value	0.279714 (rank : 262)
Query Neighborhood Hits	426	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

PDLI3_MOUSE
NC score	0.136903 (rank : 258)	θ value	3.0926 (rank : 343)
Query Neighborhood Hits	426	Target Neighborhood Hits	197	Shared Neighborhood Hits	101
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SYP2L_MOUSE
NC score	0.136733 (rank : 259)	θ value	5.27518 (rank : 385)
Query Neighborhood Hits	426	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SHAN2_MOUSE
NC score	0.133132 (rank : 260)	θ value	5.27518 (rank : 383)
Query Neighborhood Hits	426	Target Neighborhood Hits	446	Shared Neighborhood Hits	121
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SYNP2_HUMAN
NC score	0.133065 (rank : 261)	θ value	0.813845 (rank : 300)
Query Neighborhood Hits	426	Target Neighborhood Hits	323	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

KGUA_MOUSE
NC score	0.131543 (rank : 262)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	426	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.130932 (rank : 263)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	426	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

PDLI1_MOUSE
NC score	0.130272 (rank : 264)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	426	Target Neighborhood Hits	213	Shared Neighborhood Hits	100
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_HUMAN
NC score	0.127012 (rank : 265)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	426	Target Neighborhood Hits	242	Shared Neighborhood Hits	98
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

GIPC2_HUMAN
NC score	0.121946 (rank : 266)	θ value	0.47712 (rank : 281)
Query Neighborhood Hits	426	Target Neighborhood Hits	93	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

PCLO_MOUSE
NC score	0.120725 (rank : 267)	θ value	0.00390308 (rank : 214)
Query Neighborhood Hits	426	Target Neighborhood Hits	2275	Shared Neighborhood Hits	186
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

LDB3_MOUSE
NC score	0.119842 (rank : 268)	θ value	0.0431538 (rank : 239)
Query Neighborhood Hits	426	Target Neighborhood Hits	510	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

CC14B_MOUSE
NC score	0.118433 (rank : 269)	θ value	0.47712 (rank : 280)
Query Neighborhood Hits	426	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

LDB3_HUMAN
NC score	0.118017 (rank : 270)	θ value	0.0961366 (rank : 248)
Query Neighborhood Hits	426	Target Neighborhood Hits	497	Shared Neighborhood Hits	108
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PDZD6_HUMAN
NC score	0.116805 (rank : 271)	θ value	0.47712 (rank : 282)
Query Neighborhood Hits	426	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

CC14B_HUMAN
NC score	0.115904 (rank : 272)	θ value	0.813845 (rank : 297)
Query Neighborhood Hits	426	Target Neighborhood Hits	114	Shared Neighborhood Hits	61
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PDLI5_MOUSE
NC score	0.110370 (rank : 273)	θ value	0.365318 (rank : 278)
Query Neighborhood Hits	426	Target Neighborhood Hits	287	Shared Neighborhood Hits	113
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_HUMAN
NC score	0.108732 (rank : 274)	θ value	4.03905 (rank : 355)
Query Neighborhood Hits	426	Target Neighborhood Hits	322	Shared Neighborhood Hits	114
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

CC14A_MOUSE
NC score	0.108004 (rank : 275)	θ value	0.813845 (rank : 296)
Query Neighborhood Hits	426	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_HUMAN
NC score	0.105736 (rank : 276)	θ value	0.813845 (rank : 295)
Query Neighborhood Hits	426	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

FINC_HUMAN
NC score	0.103331 (rank : 277)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	426	Target Neighborhood Hits	302	Shared Neighborhood Hits	23
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.101994 (rank : 278)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	426	Target Neighborhood Hits	309	Shared Neighborhood Hits	25
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

PDLI7_HUMAN
NC score	0.097742 (rank : 279)	θ value	2.36792 (rank : 328)
Query Neighborhood Hits	426	Target Neighborhood Hits	547	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

TP4A1_HUMAN
NC score	0.094804 (rank : 280)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	426	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.094804 (rank : 281)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	426	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

SHAN1_HUMAN
NC score	0.094184 (rank : 282)	θ value	2.36792 (rank : 329)
Query Neighborhood Hits	426	Target Neighborhood Hits	1041	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

FNDC3_HUMAN
NC score	0.093473 (rank : 283)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	426	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

PDLI7_MOUSE
NC score	0.092239 (rank : 284)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	426	Target Neighborhood Hits	279	Shared Neighborhood Hits	97
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

FNDC3_MOUSE
NC score	0.087300 (rank : 285)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	426	Target Neighborhood Hits	207	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

GIPC3_HUMAN
NC score	0.086907 (rank : 286)	θ value	0.0961366 (rank : 246)
Query Neighborhood Hits	426	Target Neighborhood Hits	52	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
NC score	0.085669 (rank : 287)	θ value	0.0961366 (rank : 247)
Query Neighborhood Hits	426	Target Neighborhood Hits	53	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

CNKR2_MOUSE
NC score	0.084425 (rank : 288)	θ value	1.38821 (rank : 307)
Query Neighborhood Hits	426	Target Neighborhood Hits	197	Shared Neighborhood Hits	60
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.084359 (rank : 289)	θ value	1.38821 (rank : 306)
Query Neighborhood Hits	426	Target Neighborhood Hits	197	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

TP4A2_HUMAN
NC score	0.082181 (rank : 290)	θ value	4.03905 (rank : 361)
Query Neighborhood Hits	426	Target Neighborhood Hits	56	Shared Neighborhood Hits	37
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.082181 (rank : 291)	θ value	4.03905 (rank : 362)
Query Neighborhood Hits	426	Target Neighborhood Hits	56	Shared Neighborhood Hits	37
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

GIPC2_MOUSE
NC score	0.081883 (rank : 292)	θ value	1.81305 (rank : 317)
Query Neighborhood Hits	426	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

TP4A3_HUMAN
NC score	0.080405 (rank : 293)	θ value	3.0926 (rank : 345)
Query Neighborhood Hits	426	Target Neighborhood Hits	62	Shared Neighborhood Hits	36
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

DCC_HUMAN
NC score	0.076408 (rank : 294)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	426	Target Neighborhood Hits	583	Shared Neighborhood Hits	31
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

TP4A3_MOUSE
NC score	0.075779 (rank : 295)	θ value	1.38821 (rank : 313)
Query Neighborhood Hits	426	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

DCC_MOUSE
NC score	0.074989 (rank : 296)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	426	Target Neighborhood Hits	896	Shared Neighborhood Hits	51
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

RHPN2_MOUSE
NC score	0.074169 (rank : 297)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	426	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

NEO1_MOUSE
NC score	0.073871 (rank : 298)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	426	Target Neighborhood Hits	523	Shared Neighborhood Hits	25
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

KRIT1_HUMAN
NC score	0.073055 (rank : 299)	θ value	0.163984 (rank : 255)
Query Neighborhood Hits	426	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

NEO1_HUMAN
NC score	0.071619 (rank : 300)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	426	Target Neighborhood Hits	530	Shared Neighborhood Hits	26
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

MAMC2_MOUSE
NC score	0.069927 (rank : 301)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	426	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

PTEN_HUMAN
NC score	0.069559 (rank : 302)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	426	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.069557 (rank : 303)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	426	Target Neighborhood Hits	73	Shared Neighborhood Hits	41
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

TENN_MOUSE
NC score	0.069345 (rank : 304)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	426	Target Neighborhood Hits	484	Shared Neighborhood Hits	22
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KRIT1_MOUSE
NC score	0.068202 (rank : 305)	θ value	0.279714 (rank : 264)
Query Neighborhood Hits	426	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

COCA1_MOUSE
NC score	0.067307 (rank : 306)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	426	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MAMC2_HUMAN
NC score	0.067004 (rank : 307)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	426	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

COCA1_HUMAN
NC score	0.065942 (rank : 308)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	426	Target Neighborhood Hits	458	Shared Neighborhood Hits	27
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

SDK2_MOUSE
NC score	0.064044 (rank : 309)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	426	Target Neighborhood Hits	480	Shared Neighborhood Hits	25
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

USH2A_HUMAN
NC score	0.062665 (rank : 310)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	426	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

CSKP_HUMAN
NC score	0.062254 (rank : 311)	θ value	5.27518 (rank : 370)
Query Neighborhood Hits	426	Target Neighborhood Hits	1022	Shared Neighborhood Hits	137
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

SDK1_MOUSE
NC score	0.061342 (rank : 312)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	426	Target Neighborhood Hits	495	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
NC score	0.061337 (rank : 313)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	426	Target Neighborhood Hits	495	Shared Neighborhood Hits	23
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_HUMAN
NC score	0.060300 (rank : 314)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	426	Target Neighborhood Hits	511	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

CSKP_MOUSE
NC score	0.059966 (rank : 315)	θ value	5.27518 (rank : 371)
Query Neighborhood Hits	426	Target Neighborhood Hits	1027	Shared Neighborhood Hits	138
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CDKN3_HUMAN
NC score	0.059638 (rank : 316)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	426	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

USH2A_MOUSE
NC score	0.059212 (rank : 317)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	426	Target Neighborhood Hits	626	Shared Neighborhood Hits	24
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

TENN_HUMAN
NC score	0.059116 (rank : 318)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	426	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

PRAX_MOUSE
NC score	0.058433 (rank : 319)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	426	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

ITB4_HUMAN
NC score	0.057758 (rank : 320)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	426	Target Neighborhood Hits	458	Shared Neighborhood Hits	21
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

MY18A_MOUSE
NC score	0.057674 (rank : 321)	θ value	0.125558 (rank : 253)
Query Neighborhood Hits	426	Target Neighborhood Hits	1989	Shared Neighborhood Hits	179
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TENR_HUMAN
NC score	0.057658 (rank : 322)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	426	Target Neighborhood Hits	526	Shared Neighborhood Hits	22
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
NC score	0.057370 (rank : 323)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	426	Target Neighborhood Hits	531	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

CA106_HUMAN
NC score	0.056960 (rank : 324)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	426	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CAR11_HUMAN
NC score	0.056675 (rank : 325)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	426	Target Neighborhood Hits	690	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

PDZD8_HUMAN
NC score	0.056390 (rank : 326)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	426	Target Neighborhood Hits	185	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

TARSH_HUMAN
NC score	0.056295 (rank : 327)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	426	Target Neighborhood Hits	768	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CA106_MOUSE
NC score	0.055668 (rank : 328)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	426	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

L1CAM_MOUSE
NC score	0.055656 (rank : 329)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	426	Target Neighborhood Hits	457	Shared Neighborhood Hits	22
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_HUMAN
NC score	0.055207 (rank : 330)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	426	Target Neighborhood Hits	457	Shared Neighborhood Hits	17
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LMO7_HUMAN
NC score	0.055020 (rank : 331)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	426	Target Neighborhood Hits	507	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

COEA1_MOUSE
NC score	0.054930 (rank : 332)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	426	Target Neighborhood Hits	402	Shared Neighborhood Hits	24
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

NRCAM_MOUSE
NC score	0.054853 (rank : 333)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	426	Target Neighborhood Hits	432	Shared Neighborhood Hits	18
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

DSCL1_HUMAN
NC score	0.054817 (rank : 334)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	426	Target Neighborhood Hits	589	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DSCAM_HUMAN
NC score	0.054659 (rank : 335)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	426	Target Neighborhood Hits	524	Shared Neighborhood Hits	21
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

MY18A_HUMAN
NC score	0.054069 (rank : 336)	θ value	0.62314 (rank : 289)
Query Neighborhood Hits	426	Target Neighborhood Hits	1929	Shared Neighborhood Hits	181
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RES18_MOUSE
NC score	0.053973 (rank : 337)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	426	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

CNTN5_HUMAN
NC score	0.053082 (rank : 338)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	426	Target Neighborhood Hits	446	Shared Neighborhood Hits	17
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

NRCAM_HUMAN
NC score	0.053016 (rank : 339)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	426	Target Neighborhood Hits	439	Shared Neighborhood Hits	16
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

CO7A1_HUMAN
NC score	0.052798 (rank : 340)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	426	Target Neighborhood Hits	807	Shared Neighborhood Hits	36
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MDGA1_HUMAN
NC score	0.052306 (rank : 341)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	426	Target Neighborhood Hits	358	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

CNTN5_MOUSE
NC score	0.051979 (rank : 342)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	426	Target Neighborhood Hits	434	Shared Neighborhood Hits	18
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

RHPN2_HUMAN
NC score	0.051918 (rank : 343)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	426	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

HTRA3_MOUSE
NC score	0.051647 (rank : 344)	θ value	3.0926 (rank : 338)
Query Neighborhood Hits	426	Target Neighborhood Hits	156	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

MYOM1_MOUSE
NC score	0.051580 (rank : 345)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	426	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

CNTN2_HUMAN
NC score	0.051409 (rank : 346)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	426	Target Neighborhood Hits	440	Shared Neighborhood Hits	16
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
NC score	0.051287 (rank : 347)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	426	Target Neighborhood Hits	450	Shared Neighborhood Hits	15
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

PDC6I_MOUSE
NC score	0.051249 (rank : 348)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	426	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

MAMC1_MOUSE
NC score	0.050029 (rank : 349)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	426	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

HTRA3_HUMAN
NC score	0.048195 (rank : 350)	θ value	3.0926 (rank : 337)
Query Neighborhood Hits	426	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

MYOM2_HUMAN
NC score	0.047031 (rank : 351)	θ value	3.0926 (rank : 341)
Query Neighborhood Hits	426	Target Neighborhood Hits	341	Shared Neighborhood Hits	19
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NEUM_MOUSE
NC score	0.046521 (rank : 352)	θ value	0.0113563 (rank : 227)
Query Neighborhood Hits	426	Target Neighborhood Hits	149	Shared Neighborhood Hits	16
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

SRRM2_HUMAN
NC score	0.043119 (rank : 353)	θ value	1.81305 (rank : 323)
Query Neighborhood Hits	426	Target Neighborhood Hits	1296	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.037507 (rank : 354)	θ value	0.21417 (rank : 261)
Query Neighborhood Hits	426	Target Neighborhood Hits	1470	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DMP1_MOUSE
NC score	0.034952 (rank : 355)	θ value	3.0926 (rank : 336)
Query Neighborhood Hits	426	Target Neighborhood Hits	498	Shared Neighborhood Hits	38
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

TITIN_HUMAN
NC score	0.033107 (rank : 356)	θ value	5.27518 (rank : 387)
Query Neighborhood Hits	426	Target Neighborhood Hits	2923	Shared Neighborhood Hits	133
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MYO7A_MOUSE
NC score	0.031652 (rank : 357)	θ value	1.81305 (rank : 319)
Query Neighborhood Hits	426	Target Neighborhood Hits	235	Shared Neighborhood Hits	34
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.031266 (rank : 358)	θ value	1.81305 (rank : 318)
Query Neighborhood Hits	426	Target Neighborhood Hits	209	Shared Neighborhood Hits	35
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

SYNG_HUMAN
NC score	0.028843 (rank : 359)	θ value	0.00665767 (rank : 224)
Query Neighborhood Hits	426	Target Neighborhood Hits	160	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

LRRF1_HUMAN
NC score	0.028300 (rank : 360)	θ value	0.0563607 (rank : 241)
Query Neighborhood Hits	426	Target Neighborhood Hits	625	Shared Neighborhood Hits	35
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

AF9_HUMAN
NC score	0.028106 (rank : 361)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	426	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

MAST4_HUMAN
NC score	0.027578 (rank : 362)	θ value	0.365318 (rank : 275)
Query Neighborhood Hits	426	Target Neighborhood Hits	1804	Shared Neighborhood Hits	161
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NIPBL_HUMAN
NC score	0.027494 (rank : 363)	θ value	3.0926 (rank : 342)
Query Neighborhood Hits	426	Target Neighborhood Hits	1311	Shared Neighborhood Hits	91
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

URP1_HUMAN
NC score	0.027304 (rank : 364)	θ value	0.279714 (rank : 271)
Query Neighborhood Hits	426	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQL6, Q8IX34, Q8IYH2, Q9NWM2, Q9NXQ3	Gene names	URP1, C20orf42, KIND1
Domain Architecture
Description	Unc-112-related protein 1 (Kindlin-1) (Kindlerin) (Kindlin syndrome protein).

PAWR_HUMAN
NC score	0.026892 (rank : 365)	θ value	0.365318 (rank : 277)
Query Neighborhood Hits	426	Target Neighborhood Hits	252	Shared Neighborhood Hits	15
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

MAST2_HUMAN
NC score	0.026585 (rank : 366)	θ value	0.0113563 (rank : 226)
Query Neighborhood Hits	426	Target Neighborhood Hits	1189	Shared Neighborhood Hits	137
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST3_HUMAN
NC score	0.026115 (rank : 367)	θ value	0.0563607 (rank : 242)
Query Neighborhood Hits	426	Target Neighborhood Hits	1128	Shared Neighborhood Hits	137
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MAST2_MOUSE
NC score	0.024617 (rank : 368)	θ value	0.21417 (rank : 259)
Query Neighborhood Hits	426	Target Neighborhood Hits	1110	Shared Neighborhood Hits	136
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SI1L2_MOUSE
NC score	0.024362 (rank : 369)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	426	Target Neighborhood Hits	124	Shared Neighborhood Hits	41
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

MAST1_MOUSE
NC score	0.024231 (rank : 370)	θ value	5.27518 (rank : 380)
Query Neighborhood Hits	426	Target Neighborhood Hits	1123	Shared Neighborhood Hits	139
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NOLC1_HUMAN
NC score	0.024148 (rank : 371)	θ value	1.38821 (rank : 311)
Query Neighborhood Hits	426	Target Neighborhood Hits	452	Shared Neighborhood Hits	35
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

MAST1_HUMAN
NC score	0.023576 (rank : 372)	θ value	5.27518 (rank : 379)
Query Neighborhood Hits	426	Target Neighborhood Hits	1146	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

TACC3_HUMAN
NC score	0.021407 (rank : 373)	θ value	0.47712 (rank : 284)
Query Neighborhood Hits	426	Target Neighborhood Hits	779	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

NEUM_HUMAN
NC score	0.020433 (rank : 374)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	426	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

TGON2_HUMAN
NC score	0.020137 (rank : 375)	θ value	1.38821 (rank : 312)
Query Neighborhood Hits	426	Target Neighborhood Hits	1037	Shared Neighborhood Hits	67
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RNF34_HUMAN
NC score	0.019699 (rank : 376)	θ value	0.62314 (rank : 291)
Query Neighborhood Hits	426	Target Neighborhood Hits	153	Shared Neighborhood Hits	10
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

ZRAB2_HUMAN
NC score	0.019617 (rank : 377)	θ value	2.36792 (rank : 335)
Query Neighborhood Hits	426	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

LAP2A_HUMAN
NC score	0.018399 (rank : 378)	θ value	0.21417 (rank : 257)
Query Neighborhood Hits	426	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

LIPA2_MOUSE
NC score	0.018395 (rank : 379)	θ value	3.0926 (rank : 340)
Query Neighborhood Hits	426	Target Neighborhood Hits	1282	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LAP2B_HUMAN
NC score	0.017796 (rank : 380)	θ value	0.62314 (rank : 288)
Query Neighborhood Hits	426	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	P42167, Q14861	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

DUS5_HUMAN
NC score	0.017591 (rank : 381)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	426	Target Neighborhood Hits	82	Shared Neighborhood Hits	26
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

AUTS2_HUMAN
NC score	0.017372 (rank : 382)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	426	Target Neighborhood Hits	342	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

NTKL_HUMAN
NC score	0.017187 (rank : 383)	θ value	0.163984 (rank : 256)
Query Neighborhood Hits	426	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

DAXX_HUMAN
NC score	0.016837 (rank : 384)	θ value	1.81305 (rank : 314)
Query Neighborhood Hits	426	Target Neighborhood Hits	207	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

BRCA2_MOUSE
NC score	0.016493 (rank : 385)	θ value	0.813845 (rank : 294)
Query Neighborhood Hits	426	Target Neighborhood Hits	222	Shared Neighborhood Hits	12
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

SET1A_HUMAN
NC score	0.016025 (rank : 386)	θ value	3.0926 (rank : 344)
Query Neighborhood Hits	426	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

BAT2_HUMAN
NC score	0.015555 (rank : 387)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	426	Target Neighborhood Hits	931	Shared Neighborhood Hits	53
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DMN_HUMAN
NC score	0.015193 (rank : 388)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	426	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

JIP4_MOUSE
NC score	0.015035 (rank : 389)	θ value	0.279714 (rank : 263)
Query Neighborhood Hits	426	Target Neighborhood Hits	593	Shared Neighborhood Hits	33
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

LIPA2_HUMAN
NC score	0.014593 (rank : 390)	θ value	3.0926 (rank : 339)
Query Neighborhood Hits	426	Target Neighborhood Hits	1044	Shared Neighborhood Hits	53
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

YTDC1_HUMAN
NC score	0.014547 (rank : 391)	θ value	0.62314 (rank : 293)
Query Neighborhood Hits	426	Target Neighborhood Hits	458	Shared Neighborhood Hits	36
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

NKTR_HUMAN
NC score	0.014486 (rank : 392)	θ value	0.279714 (rank : 266)
Query Neighborhood Hits	426	Target Neighborhood Hits	658	Shared Neighborhood Hits	44
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TOIP2_HUMAN
NC score	0.014236 (rank : 393)	θ value	0.365318 (rank : 279)
Query Neighborhood Hits	426	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

SYAM_MOUSE
NC score	0.013843 (rank : 394)	θ value	0.813845 (rank : 299)
Query Neighborhood Hits	426	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q14CH7, Q68FH3, Q69ZM9	Gene names	Aarsl, Aars2, Kiaa1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

MYO5A_MOUSE
NC score	0.013590 (rank : 395)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	426	Target Neighborhood Hits	1117	Shared Neighborhood Hits	49
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

DOK7_HUMAN
NC score	0.013409 (rank : 396)	θ value	1.81305 (rank : 315)
Query Neighborhood Hits	426	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q18PE1, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1	Gene names	DOK7, C4orf25
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

JIP4_HUMAN
NC score	0.013370 (rank : 397)	θ value	2.36792 (rank : 326)
Query Neighborhood Hits	426	Target Neighborhood Hits	585	Shared Neighborhood Hits	29
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

SYAM_HUMAN
NC score	0.013155 (rank : 398)	θ value	1.06291 (rank : 304)
Query Neighborhood Hits	426	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTZ9, Q8N198, Q96D02, Q9ULF0	Gene names	AARSL, AARS2, KIAA1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

DNL1_HUMAN
NC score	0.012924 (rank : 399)	θ value	1.38821 (rank : 308)
Query Neighborhood Hits	426	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

CN155_HUMAN
NC score	0.012896 (rank : 400)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	426	Target Neighborhood Hits	385	Shared Neighborhood Hits	30
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

SYNPO_HUMAN
NC score	0.012702 (rank : 401)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	426	Target Neighborhood Hits	281	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

HUWE1_MOUSE
NC score	0.012504 (rank : 402)	θ value	0.125558 (rank : 252)
Query Neighborhood Hits	426	Target Neighborhood Hits	406	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

MAP2_HUMAN
NC score	0.012405 (rank : 403)	θ value	0.21417 (rank : 258)
Query Neighborhood Hits	426	Target Neighborhood Hits	348	Shared Neighborhood Hits	19
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

LIMK2_MOUSE
NC score	0.012359 (rank : 404)	θ value	0.0563607 (rank : 240)
Query Neighborhood Hits	426	Target Neighborhood Hits	998	Shared Neighborhood Hits	83
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

CASC3_MOUSE
NC score	0.012330 (rank : 405)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	426	Target Neighborhood Hits	333	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

GAB1_HUMAN
NC score	0.012091 (rank : 406)	θ value	0.813845 (rank : 298)
Query Neighborhood Hits	426	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

AMOT_HUMAN
NC score	0.012043 (rank : 407)	θ value	1.38821 (rank : 305)
Query Neighborhood Hits	426	Target Neighborhood Hits	712	Shared Neighborhood Hits	39
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

MPIP1_HUMAN
NC score	0.011423 (rank : 408)	θ value	0.365318 (rank : 276)
Query Neighborhood Hits	426	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P30304, Q8IZH5, Q96IL3, Q9H2F2	Gene names	CDC25A
Domain Architecture
Description	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A).

MYCN_HUMAN
NC score	0.010609 (rank : 409)	θ value	0.279714 (rank : 265)
Query Neighborhood Hits	426	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

CKAP5_HUMAN
NC score	0.010237 (rank : 410)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	426	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

NUB1_HUMAN
NC score	0.010188 (rank : 411)	θ value	1.81305 (rank : 320)
Query Neighborhood Hits	426	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5A7, O95422, Q8IX22, Q9BXR2	Gene names	NUB1, NYREN18
Domain Architecture
Description	NEDD8 ultimate buster 1 (NY-REN-18 antigen).

HUWE1_HUMAN
NC score	0.010062 (rank : 412)	θ value	1.38821 (rank : 310)
Query Neighborhood Hits	426	Target Neighborhood Hits	443	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

NTKL_MOUSE
NC score	0.009944 (rank : 413)	θ value	0.62314 (rank : 290)
Query Neighborhood Hits	426	Target Neighborhood Hits	326	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

RM11_HUMAN
NC score	0.009809 (rank : 414)	θ value	4.03905 (rank : 357)
Query Neighborhood Hits	426	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3B7, Q96Q73	Gene names	MRPL11
Domain Architecture
Description	39S ribosomal protein L11, mitochondrial precursor (L11mt) (MRP-L11).

LIMK1_HUMAN
NC score	0.009769 (rank : 415)	θ value	2.36792 (rank : 327)
Query Neighborhood Hits	426	Target Neighborhood Hits	1005	Shared Neighborhood Hits	94
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK2_HUMAN
NC score	0.009457 (rank : 416)	θ value	0.365318 (rank : 274)
Query Neighborhood Hits	426	Target Neighborhood Hits	986	Shared Neighborhood Hits	86
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

TCAL5_HUMAN
NC score	0.009244 (rank : 417)	θ value	5.27518 (rank : 386)
Query Neighborhood Hits	426	Target Neighborhood Hits	806	Shared Neighborhood Hits	43
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ZFAN3_MOUSE
NC score	0.009216 (rank : 418)	θ value	3.0926 (rank : 346)
Query Neighborhood Hits	426	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q497H0, Q8K230, Q8R2V7, Q8R3V1	Gene names	Zfand3, Tex27
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 3 (Testis-expressed sequence 27).

LIMK1_MOUSE
NC score	0.009185 (rank : 419)	θ value	1.06291 (rank : 302)
Query Neighborhood Hits	426	Target Neighborhood Hits	1008	Shared Neighborhood Hits	96
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

XRCC4_MOUSE
NC score	0.008958 (rank : 420)	θ value	2.36792 (rank : 333)
Query Neighborhood Hits	426	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q924T3, Q8BKC9, Q8BU02, Q9D6U6	Gene names	Xrcc4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

NGAP_HUMAN
NC score	0.008806 (rank : 421)	θ value	5.27518 (rank : 381)
Query Neighborhood Hits	426	Target Neighborhood Hits	517	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

GYS1_MOUSE
NC score	0.008624 (rank : 422)	θ value	5.27518 (rank : 375)
Query Neighborhood Hits	426	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1E4	Gene names	Gys1, Gys
Domain Architecture
Description	Glycogen [starch] synthase, muscle (EC 2.4.1.11).

GYS3_MOUSE
NC score	0.008594 (rank : 423)	θ value	5.27518 (rank : 376)
Query Neighborhood Hits	426	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P54859	Gene names	Gys3
Domain Architecture
Description	Glycogen [starch] synthase, brain (EC 2.4.1.11).

FMR1_HUMAN
NC score	0.008404 (rank : 424)	θ value	1.38821 (rank : 309)
Query Neighborhood Hits	426	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

GYS1_HUMAN
NC score	0.008369 (rank : 425)	θ value	5.27518 (rank : 374)
Query Neighborhood Hits	426	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P13807	Gene names	GYS1, GYS
Domain Architecture
Description	Glycogen [starch] synthase, muscle (EC 2.4.1.11).

ZC3H3_MOUSE
NC score	0.008268 (rank : 426)	θ value	6.88961 (rank : 408)
Query Neighborhood Hits	426	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

BSCL2_HUMAN
NC score	0.007957 (rank : 427)	θ value	6.88961 (rank : 392)
Query Neighborhood Hits	426	Target Neighborhood Hits	148	Shared Neighborhood Hits	13
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

SAFB2_HUMAN
NC score	0.007886 (rank : 428)	θ value	0.21417 (rank : 260)
Query Neighborhood Hits	426	Target Neighborhood Hits	720	Shared Neighborhood Hits	29
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

FXR2_MOUSE
NC score	0.006842 (rank : 429)	θ value	4.03905 (rank : 348)
Query Neighborhood Hits	426	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

CLH_MOUSE
NC score	0.006545 (rank : 430)	θ value	5.27518 (rank : 369)
Query Neighborhood Hits	426	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FD5	Gene names	Cltc
Domain Architecture	No domain graphic available
Description	Clathrin heavy chain.

CLH1_HUMAN
NC score	0.006542 (rank : 431)	θ value	5.27518 (rank : 368)
Query Neighborhood Hits	426	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q00610, Q6N0A0, Q86TF2	Gene names	CLTC, CLH17, KIAA0034
Domain Architecture
Description	Clathrin heavy chain 1 (CLH-17).

TDRD3_MOUSE
NC score	0.006538 (rank : 432)	θ value	4.03905 (rank : 360)
Query Neighborhood Hits	426	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W18, Q8BZW6	Gene names	Tdrd3
Domain Architecture
Description	Tudor domain-containing protein 3.

SYT14_HUMAN
NC score	0.006519 (rank : 433)	θ value	0.813845 (rank : 301)
Query Neighborhood Hits	426	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

CD2_HUMAN
NC score	0.005994 (rank : 434)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	426	Target Neighborhood Hits	504	Shared Neighborhood Hits	20
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

AFF2_MOUSE
NC score	0.005957 (rank : 435)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	426	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

CSPG2_MOUSE
NC score	0.005882 (rank : 436)	θ value	0.125558 (rank : 251)
Query Neighborhood Hits	426	Target Neighborhood Hits	711	Shared Neighborhood Hits	26
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CD017_HUMAN
NC score	0.005761 (rank : 437)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	426	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q53FE4, Q6FI84, Q6IS77, Q9H0D9	Gene names	C4orf17
Domain Architecture	No domain graphic available
Description	Protein C4orf17.

DCP1B_HUMAN
NC score	0.005701 (rank : 438)	θ value	5.27518 (rank : 372)
Query Neighborhood Hits	426	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

STX18_MOUSE
NC score	0.005698 (rank : 439)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	426	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDS8, Q3TDJ0, Q9D8T6	Gene names	Stx18
Domain Architecture	No domain graphic available
Description	Syntaxin-18.

SV2C_HUMAN
NC score	0.005121 (rank : 440)	θ value	1.81305 (rank : 324)
Query Neighborhood Hits	426	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

XRCC1_MOUSE
NC score	0.005081 (rank : 441)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	426	Target Neighborhood Hits	242	Shared Neighborhood Hits	17
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

RAI14_HUMAN
NC score	0.004918 (rank : 442)	θ value	1.06291 (rank : 303)
Query Neighborhood Hits	426	Target Neighborhood Hits	1367	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

PER1_HUMAN
NC score	0.004906 (rank : 443)	θ value	4.03905 (rank : 356)
Query Neighborhood Hits	426	Target Neighborhood Hits	215	Shared Neighborhood Hits	13
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

AKAP6_HUMAN
NC score	0.004731 (rank : 444)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	426	Target Neighborhood Hits	263	Shared Neighborhood Hits	13
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

ATRX_HUMAN
NC score	0.004336 (rank : 445)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	426	Target Neighborhood Hits	842	Shared Neighborhood Hits	43
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ZC3H6_HUMAN
NC score	0.004255 (rank : 446)	θ value	4.03905 (rank : 363)
Query Neighborhood Hits	426	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

SV2C_MOUSE
NC score	0.003957 (rank : 447)	θ value	5.27518 (rank : 384)
Query Neighborhood Hits	426	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZS6	Gene names	Sv2c, Kiaa1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C (Synaptic vesicle protein 2C).

MCPH1_HUMAN
NC score	0.003926 (rank : 448)	θ value	6.88961 (rank : 397)
Query Neighborhood Hits	426	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

SENP7_HUMAN
NC score	0.003734 (rank : 449)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	426	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

GGA1_MOUSE
NC score	0.003361 (rank : 450)	θ value	4.03905 (rank : 349)
Query Neighborhood Hits	426	Target Neighborhood Hits	128	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

ZP1_MOUSE
NC score	0.002890 (rank : 451)	θ value	6.88961 (rank : 409)
Query Neighborhood Hits	426	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q62005, Q62016	Gene names	Zp1
Domain Architecture
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

BRD4_HUMAN
NC score	0.002369 (rank : 452)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	426	Target Neighborhood Hits	851	Shared Neighborhood Hits	44
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

AP1G2_HUMAN
NC score	0.002259 (rank : 453)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	426	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

TAOK1_MOUSE
NC score	0.001526 (rank : 454)	θ value	2.36792 (rank : 331)
Query Neighborhood Hits	426	Target Neighborhood Hits	1720	Shared Neighborhood Hits	64
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

RYR2_HUMAN
NC score	0.001490 (rank : 455)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	426	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

TULP1_MOUSE
NC score	0.001288 (rank : 456)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	426	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

TAOK1_HUMAN
NC score	0.001182 (rank : 457)	θ value	2.36792 (rank : 330)
Query Neighborhood Hits	426	Target Neighborhood Hits	1734	Shared Neighborhood Hits	63
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

BOP1_HUMAN
NC score	0.001166 (rank : 458)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	426	Target Neighborhood Hits	257	Shared Neighborhood Hits	6
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

DMXL1_HUMAN
NC score	0.000781 (rank : 459)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	426	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

PGCB_HUMAN
NC score	0.000402 (rank : 460)	θ value	1.81305 (rank : 322)
Query Neighborhood Hits	426	Target Neighborhood Hits	478	Shared Neighborhood Hits	16
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ZFYV9_HUMAN
NC score	0.000060 (rank : 461)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	426	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

JADE3_HUMAN
NC score	-0.000126 (rank : 462)	θ value	5.27518 (rank : 377)
Query Neighborhood Hits	426	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

K1C18_HUMAN
NC score	-0.000155 (rank : 463)	θ value	5.27518 (rank : 378)
Query Neighborhood Hits	426	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

RBM28_HUMAN
NC score	-0.000429 (rank : 464)	θ value	5.27518 (rank : 382)
Query Neighborhood Hits	426	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

TAOK3_MOUSE
NC score	-0.001044 (rank : 465)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	426	Target Neighborhood Hits	1458	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

NVL_MOUSE
NC score	-0.001433 (rank : 466)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	426	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

TAOK3_HUMAN
NC score	-0.001541 (rank : 467)	θ value	4.03905 (rank : 359)
Query Neighborhood Hits	426	Target Neighborhood Hits	1494	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

E2AK4_HUMAN
NC score	-0.002571 (rank : 468)	θ value	0.62314 (rank : 286)
Query Neighborhood Hits	426	Target Neighborhood Hits	1012	Shared Neighborhood Hits	41
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

NR4A1_MOUSE
NC score	-0.002610 (rank : 469)	θ value	4.03905 (rank : 354)
Query Neighborhood Hits	426	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

WNK2_HUMAN
NC score	-0.002683 (rank : 470)	θ value	2.36792 (rank : 332)
Query Neighborhood Hits	426	Target Neighborhood Hits	1407	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MP2K4_MOUSE
NC score	-0.004171 (rank : 471)	θ value	4.03905 (rank : 351)
Query Neighborhood Hits	426	Target Neighborhood Hits	833	Shared Neighborhood Hits	31
SwissProt Accessions	P47809	Gene names	Map2k4, Jnkk1, Prkmk4, Sek1, Serk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SEK1).

MP2K4_HUMAN
NC score	-0.004180 (rank : 472)	θ value	4.03905 (rank : 350)
Query Neighborhood Hits	426	Target Neighborhood Hits	832	Shared Neighborhood Hits	31
SwissProt Accessions	P45985, Q5U0B8	Gene names	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

PCD19_MOUSE
NC score	-0.004457 (rank : 473)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	426	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TF3, Q8BL13	Gene names	Pcdh19, Kiaa1313
Domain Architecture	No domain graphic available
Description	Protocadherin-19 precursor.

PCD19_HUMAN
NC score	-0.004465 (rank : 474)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	426	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAB3, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3	Gene names	PCDH19, KIAA1313
Domain Architecture
Description	Protocadherin-19 precursor.

CD2L2_HUMAN
NC score	-0.004916 (rank : 475)	θ value	6.88961 (rank : 393)
Query Neighborhood Hits	426	Target Neighborhood Hits	1439	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CD2L7_HUMAN
NC score	-0.006372 (rank : 476)	θ value	0.62314 (rank : 285)
Query Neighborhood Hits	426	Target Neighborhood Hits	1275	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

PKN1_HUMAN
NC score	-0.006463 (rank : 477)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	426	Target Neighborhood Hits	886	Shared Neighborhood Hits	32
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

MST4_HUMAN
NC score	-0.007216 (rank : 478)	θ value	4.03905 (rank : 352)
Query Neighborhood Hits	426	Target Neighborhood Hits	852	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MST4_MOUSE
NC score	-0.007223 (rank : 479)	θ value	4.03905 (rank : 353)
Query Neighborhood Hits	426	Target Neighborhood Hits	860	Shared Neighborhood Hits	29
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

BRAF1_HUMAN
NC score	-0.007829 (rank : 480)	θ value	4.03905 (rank : 347)
Query Neighborhood Hits	426	Target Neighborhood Hits	883	Shared Neighborhood Hits	30
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

ZFP95_HUMAN
NC score	-0.012338 (rank : 481)	θ value	2.36792 (rank : 334)
Query Neighborhood Hits	426	Target Neighborhood Hits	775	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

ZN319_MOUSE
NC score	-0.012574 (rank : 482)	θ value	5.27518 (rank : 388)
Query Neighborhood Hits	426	Target Neighborhood Hits	762	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERR8	Gene names	Znf319, Zfp319
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

ZN467_MOUSE
NC score	-0.012643 (rank : 483)	θ value	5.27518 (rank : 389)
Query Neighborhood Hits	426	Target Neighborhood Hits	794	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZL0, Q9JJ98	Gene names	Znf467, Ezi, Zfp467
Domain Architecture	No domain graphic available
Description	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI).

EVI1_MOUSE
NC score	-0.012724 (rank : 484)	θ value	5.27518 (rank : 373)
Query Neighborhood Hits	426	Target Neighborhood Hits	826	Shared Neighborhood Hits	10
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.