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Network neighborhood for query Sequence : E41LA_HUMAN

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E41LA_HUMAN
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E41LA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	87	Target Neighborhood Hits	87	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
θ value	0 (rank : 2)	NC score	0.996444 (rank : 2)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L5_HUMAN
θ value	5.33382e-77 (rank : 3)	NC score	0.972152 (rank : 4)
Query Neighborhood Hits	87	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
θ value	3.45727e-76 (rank : 4)	NC score	0.972385 (rank : 3)
Query Neighborhood Hits	87	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LB_HUMAN
θ value	2.92676e-75 (rank : 5)	NC score	0.967006 (rank : 7)
Query Neighborhood Hits	87	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

PTN4_HUMAN
θ value	2.47765e-74 (rank : 6)	NC score	0.680963 (rank : 35)
Query Neighborhood Hits	87	Target Neighborhood Hits	303	Shared Neighborhood Hits	54
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

E41L3_HUMAN
θ value	3.70236e-70 (rank : 7)	NC score	0.958406 (rank : 8)
Query Neighborhood Hits	87	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L1_MOUSE
θ value	1.40689e-69 (rank : 8)	NC score	0.956585 (rank : 9)
Query Neighborhood Hits	87	Target Neighborhood Hits	106	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
θ value	4.09345e-69 (rank : 9)	NC score	0.952151 (rank : 11)
Query Neighborhood Hits	87	Target Neighborhood Hits	180	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_MOUSE
θ value	1.5555e-68 (rank : 10)	NC score	0.945135 (rank : 13)
Query Neighborhood Hits	87	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

FRMD5_MOUSE
θ value	2.65329e-68 (rank : 11)	NC score	0.970542 (rank : 5)
Query Neighborhood Hits	87	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

41_HUMAN
θ value	7.71989e-68 (rank : 12)	NC score	0.953568 (rank : 10)
Query Neighborhood Hits	87	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

FRMD5_HUMAN
θ value	2.93355e-67 (rank : 13)	NC score	0.968595 (rank : 6)
Query Neighborhood Hits	87	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

41_MOUSE
θ value	2.74572e-65 (rank : 14)	NC score	0.950157 (rank : 12)
Query Neighborhood Hits	87	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L2_HUMAN
θ value	3.58603e-65 (rank : 15)	NC score	0.940362 (rank : 14)
Query Neighborhood Hits	87	Target Neighborhood Hits	287	Shared Neighborhood Hits	53
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
θ value	2.84138e-62 (rank : 16)	NC score	0.918005 (rank : 15)
Query Neighborhood Hits	87	Target Neighborhood Hits	459	Shared Neighborhood Hits	60
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

PTN3_HUMAN
θ value	2.1121e-49 (rank : 17)	NC score	0.653753 (rank : 37)
Query Neighborhood Hits	87	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

FARP1_HUMAN
θ value	1.51363e-47 (rank : 18)	NC score	0.788577 (rank : 23)
Query Neighborhood Hits	87	Target Neighborhood Hits	241	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_MOUSE
θ value	5.95217e-44 (rank : 19)	NC score	0.756131 (rank : 26)
Query Neighborhood Hits	87	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_HUMAN
θ value	7.27602e-42 (rank : 20)	NC score	0.763844 (rank : 25)
Query Neighborhood Hits	87	Target Neighborhood Hits	240	Shared Neighborhood Hits	50
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN21_MOUSE
θ value	2.77131e-33 (rank : 21)	NC score	0.627659 (rank : 38)
Query Neighborhood Hits	87	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
θ value	1.79631e-32 (rank : 22)	NC score	0.625575 (rank : 39)
Query Neighborhood Hits	87	Target Neighborhood Hits	143	Shared Neighborhood Hits	47
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

EZRI_HUMAN
θ value	1.98606e-31 (rank : 23)	NC score	0.751994 (rank : 27)
Query Neighborhood Hits	87	Target Neighborhood Hits	663	Shared Neighborhood Hits	49
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	1.98606e-31 (rank : 24)	NC score	0.747338 (rank : 28)
Query Neighborhood Hits	87	Target Neighborhood Hits	693	Shared Neighborhood Hits	49
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PTN14_MOUSE
θ value	5.77852e-31 (rank : 25)	NC score	0.612848 (rank : 40)
Query Neighborhood Hits	87	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

RADI_HUMAN
θ value	9.8567e-31 (rank : 26)	NC score	0.733382 (rank : 29)
Query Neighborhood Hits	87	Target Neighborhood Hits	741	Shared Neighborhood Hits	49
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	9.8567e-31 (rank : 27)	NC score	0.729733 (rank : 30)
Query Neighborhood Hits	87	Target Neighborhood Hits	773	Shared Neighborhood Hits	50
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MOES_HUMAN
θ value	8.3442e-30 (rank : 28)	NC score	0.689017 (rank : 33)
Query Neighborhood Hits	87	Target Neighborhood Hits	892	Shared Neighborhood Hits	51
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
θ value	8.3442e-30 (rank : 29)	NC score	0.681432 (rank : 34)
Query Neighborhood Hits	87	Target Neighborhood Hits	923	Shared Neighborhood Hits	51
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN14_HUMAN
θ value	1.85889e-29 (rank : 30)	NC score	0.604937 (rank : 41)
Query Neighborhood Hits	87	Target Neighborhood Hits	163	Shared Neighborhood Hits	51
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

MERL_HUMAN
θ value	1.02001e-27 (rank : 31)	NC score	0.788070 (rank : 24)
Query Neighborhood Hits	87	Target Neighborhood Hits	532	Shared Neighborhood Hits	50
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	1.33217e-27 (rank : 32)	NC score	0.788786 (rank : 22)
Query Neighborhood Hits	87	Target Neighborhood Hits	524	Shared Neighborhood Hits	51
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTN13_HUMAN
θ value	2.27234e-27 (rank : 33)	NC score	0.489529 (rank : 43)
Query Neighborhood Hits	87	Target Neighborhood Hits	471	Shared Neighborhood Hits	56
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	8.63488e-27 (rank : 34)	NC score	0.498954 (rank : 42)
Query Neighborhood Hits	87	Target Neighborhood Hits	426	Shared Neighborhood Hits	54
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

MYLIP_HUMAN
θ value	1.16704e-23 (rank : 35)	NC score	0.846554 (rank : 17)
Query Neighborhood Hits	87	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_MOUSE
θ value	1.16704e-23 (rank : 36)	NC score	0.862704 (rank : 16)
Query Neighborhood Hits	87	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4A_MOUSE
θ value	4.43474e-23 (rank : 37)	NC score	0.805887 (rank : 20)
Query Neighborhood Hits	87	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
θ value	7.56453e-23 (rank : 38)	NC score	0.804877 (rank : 21)
Query Neighborhood Hits	87	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4B_MOUSE
θ value	9.24701e-21 (rank : 39)	NC score	0.808257 (rank : 19)
Query Neighborhood Hits	87	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4B_HUMAN
θ value	1.2077e-20 (rank : 40)	NC score	0.810874 (rank : 18)
Query Neighborhood Hits	87	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRMD6_HUMAN
θ value	7.09661e-13 (rank : 41)	NC score	0.700185 (rank : 32)
Query Neighborhood Hits	87	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD6_MOUSE
θ value	4.59992e-12 (rank : 42)	NC score	0.706082 (rank : 31)
Query Neighborhood Hits	87	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

TLN2_HUMAN
θ value	9.59137e-10 (rank : 43)	NC score	0.441439 (rank : 47)
Query Neighborhood Hits	87	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	1.25267e-09 (rank : 44)	NC score	0.446148 (rank : 45)
Query Neighborhood Hits	87	Target Neighborhood Hits	149	Shared Neighborhood Hits	48
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_HUMAN
θ value	1.63604e-09 (rank : 45)	NC score	0.447588 (rank : 44)
Query Neighborhood Hits	87	Target Neighborhood Hits	218	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	1.63604e-09 (rank : 46)	NC score	0.444518 (rank : 46)
Query Neighborhood Hits	87	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

FRMD1_HUMAN
θ value	1.53129e-07 (rank : 47)	NC score	0.674434 (rank : 36)
Query Neighborhood Hits	87	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

PCLO_MOUSE
θ value	0.0113563 (rank : 48)	NC score	0.031576 (rank : 133)
Query Neighborhood Hits	87	Target Neighborhood Hits	2275	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TARA_MOUSE
θ value	0.0330416 (rank : 49)	NC score	0.040706 (rank : 125)
Query Neighborhood Hits	87	Target Neighborhood Hits	1133	Shared Neighborhood Hits	29
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WAPL_HUMAN
θ value	0.0431538 (rank : 50)	NC score	0.047249 (rank : 122)
Query Neighborhood Hits	87	Target Neighborhood Hits	122	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

PCLO_HUMAN
θ value	0.0563607 (rank : 51)	NC score	0.029512 (rank : 134)
Query Neighborhood Hits	87	Target Neighborhood Hits	2046	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NPBL_MOUSE
θ value	0.0736092 (rank : 52)	NC score	0.052134 (rank : 119)
Query Neighborhood Hits	87	Target Neighborhood Hits	1041	Shared Neighborhood Hits	35
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PHF20_MOUSE
θ value	0.0736092 (rank : 53)	NC score	0.054037 (rank : 117)
Query Neighborhood Hits	87	Target Neighborhood Hits	513	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

NIPBL_HUMAN
θ value	0.125558 (rank : 54)	NC score	0.051307 (rank : 120)
Query Neighborhood Hits	87	Target Neighborhood Hits	1311	Shared Neighborhood Hits	37
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

WAPL_MOUSE
θ value	0.163984 (rank : 55)	NC score	0.047144 (rank : 123)
Query Neighborhood Hits	87	Target Neighborhood Hits	158	Shared Neighborhood Hits	11
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

DDX21_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.014524 (rank : 144)
Query Neighborhood Hits	87	Target Neighborhood Hits	308	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

FUSIP_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.019180 (rank : 141)
Query Neighborhood Hits	87	Target Neighborhood Hits	230	Shared Neighborhood Hits	12
SwissProt Accessions	O75494, O60572, Q96G09, Q96P17	Gene names	FUSIP1, TASR
Domain Architecture
Description	FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (40 kDa SR-repressor protein) (SRrp40) (Splicing factor SRp38).

FUSIP_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.019180 (rank : 142)
Query Neighborhood Hits	87	Target Neighborhood Hits	230	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R0U0, O70307, O88468, Q3TGW7, Q8CFZ1, Q9R0T9	Gene names	Fusip1, Nssr
Domain Architecture
Description	FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (Neural-specific SR protein) (Neural-salient serine/arginine-rich protein).

ZO2_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.039506 (rank : 126)
Query Neighborhood Hits	87	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

IWS1_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.039462 (rank : 127)
Query Neighborhood Hits	87	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NCOR1_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.034702 (rank : 130)
Query Neighborhood Hits	87	Target Neighborhood Hits	521	Shared Neighborhood Hits	25
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

SRRM1_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.026235 (rank : 136)
Query Neighborhood Hits	87	Target Neighborhood Hits	966	Shared Neighborhood Hits	23
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.027257 (rank : 135)
Query Neighborhood Hits	87	Target Neighborhood Hits	1470	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCOF_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.020783 (rank : 140)
Query Neighborhood Hits	87	Target Neighborhood Hits	543	Shared Neighborhood Hits	17
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CTR9_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.022024 (rank : 137)
Query Neighborhood Hits	87	Target Neighborhood Hits	427	Shared Neighborhood Hits	15
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

PHF20_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.035629 (rank : 129)
Query Neighborhood Hits	87	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

SFRIP_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.032448 (rank : 132)
Query Neighborhood Hits	87	Target Neighborhood Hits	530	Shared Neighborhood Hits	21
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

PAR3L_HUMAN
θ value	1.81305 (rank : 68)	NC score	0.044639 (rank : 124)
Query Neighborhood Hits	87	Target Neighborhood Hits	297	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

SRRM2_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.038257 (rank : 128)
Query Neighborhood Hits	87	Target Neighborhood Hits	1296	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

WDHD1_MOUSE
θ value	1.81305 (rank : 70)	NC score	0.014055 (rank : 145)
Query Neighborhood Hits	87	Target Neighborhood Hits	414	Shared Neighborhood Hits	10
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

SRPK1_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.001104 (rank : 156)
Query Neighborhood Hits	87	Target Neighborhood Hits	639	Shared Neighborhood Hits	7
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TXND2_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.033412 (rank : 131)
Query Neighborhood Hits	87	Target Neighborhood Hits	828	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

MIER1_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.010541 (rank : 148)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

CE290_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.015692 (rank : 143)
Query Neighborhood Hits	87	Target Neighborhood Hits	1553	Shared Neighborhood Hits	19
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

PO121_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.009402 (rank : 150)
Query Neighborhood Hits	87	Target Neighborhood Hits	344	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SRRM1_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.021342 (rank : 138)
Query Neighborhood Hits	87	Target Neighborhood Hits	690	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

KBTBA_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.004262 (rank : 153)
Query Neighborhood Hits	87	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

STOX1_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.021013 (rank : 139)
Query Neighborhood Hits	87	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZVD7, Q4F8Q6, Q5I946, Q5I947, Q5I948, Q5VX38, Q5VX39, Q6ZRY3, Q96LR3, Q96LS0	Gene names	STOX1, C10orf24
Domain Architecture	No domain graphic available
Description	Storkhead-box protein 1 (Winged helix domain-containing protein).

YETS2_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.007087 (rank : 152)
Query Neighborhood Hits	87	Target Neighborhood Hits	212	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ABCA4_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.001159 (rank : 155)
Query Neighborhood Hits	87	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

AKT2_HUMAN
θ value	6.88961 (rank : 81)	NC score	-0.004883 (rank : 158)
Query Neighborhood Hits	87	Target Neighborhood Hits	878	Shared Neighborhood Hits	4
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

BCOR_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.009891 (rank : 149)
Query Neighborhood Hits	87	Target Neighborhood Hits	609	Shared Neighborhood Hits	13
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.007722 (rank : 151)
Query Neighborhood Hits	87	Target Neighborhood Hits	521	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

MRCKB_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.012988 (rank : 147)
Query Neighborhood Hits	87	Target Neighborhood Hits	2239	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NKTR_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.013971 (rank : 146)
Query Neighborhood Hits	87	Target Neighborhood Hits	658	Shared Neighborhood Hits	27
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

SPG16_HUMAN
θ value	8.99809 (rank : 86)	NC score	-0.001108 (rank : 157)
Query Neighborhood Hits	87	Target Neighborhood Hits	361	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

ZN512_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.001190 (rank : 154)
Query Neighborhood Hits	87	Target Neighborhood Hits	444	Shared Neighborhood Hits	2
SwissProt Accessions	Q96ME7, Q96JM0	Gene names	ZNF512, KIAA1805
Domain Architecture	No domain graphic available
Description	Zinc finger protein 512.

CA106_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.096977 (rank : 87)
Query Neighborhood Hits	87	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.095638 (rank : 88)
Query Neighborhood Hits	87	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CD45_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.105499 (rank : 82)
Query Neighborhood Hits	87	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.110104 (rank : 71)
Query Neighborhood Hits	87	Target Neighborhood Hits	178	Shared Neighborhood Hits	11
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

FGD1_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.054663 (rank : 116)
Query Neighborhood Hits	87	Target Neighborhood Hits	367	Shared Neighborhood Hits	10
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.052267 (rank : 118)
Query Neighborhood Hits	87	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD4_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.054986 (rank : 115)
Query Neighborhood Hits	87	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.055456 (rank : 113)
Query Neighborhood Hits	87	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD5_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.058411 (rank : 109)
Query Neighborhood Hits	87	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.054994 (rank : 114)
Query Neighborhood Hits	87	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.056949 (rank : 111)
Query Neighborhood Hits	87	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.057140 (rank : 110)
Query Neighborhood Hits	87	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HIP1R_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.059935 (rank : 107)
Query Neighborhood Hits	87	Target Neighborhood Hits	809	Shared Neighborhood Hits	20
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.055479 (rank : 112)
Query Neighborhood Hits	87	Target Neighborhood Hits	959	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.059072 (rank : 108)
Query Neighborhood Hits	87	Target Neighborhood Hits	1016	Shared Neighborhood Hits	21
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KRIT1_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.091640 (rank : 90)
Query Neighborhood Hits	87	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.084862 (rank : 100)
Query Neighborhood Hits	87	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MESD1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.061787 (rank : 106)
Query Neighborhood Hits	87	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.063528 (rank : 105)
Query Neighborhood Hits	87	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

PKHA6_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.051131 (rank : 121)
Query Neighborhood Hits	87	Target Neighborhood Hits	591	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PTN11_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.109511 (rank : 75)
Query Neighborhood Hits	87	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.109518 (rank : 74)
Query Neighborhood Hits	87	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.116522 (rank : 60)
Query Neighborhood Hits	87	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.116510 (rank : 61)
Query Neighborhood Hits	87	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.125965 (rank : 50)
Query Neighborhood Hits	87	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.122098 (rank : 53)
Query Neighborhood Hits	87	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.125843 (rank : 52)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.126236 (rank : 49)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.119530 (rank : 56)
Query Neighborhood Hits	87	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.117665 (rank : 58)
Query Neighborhood Hits	87	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.109529 (rank : 73)
Query Neighborhood Hits	87	Target Neighborhood Hits	646	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.108537 (rank : 79)
Query Neighborhood Hits	87	Target Neighborhood Hits	726	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.125848 (rank : 51)
Query Neighborhood Hits	87	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.127180 (rank : 48)
Query Neighborhood Hits	87	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.109458 (rank : 76)
Query Neighborhood Hits	87	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.109414 (rank : 77)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.116421 (rank : 62)
Query Neighborhood Hits	87	Target Neighborhood Hits	234	Shared Neighborhood Hits	8
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.116403 (rank : 63)
Query Neighborhood Hits	87	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.116660 (rank : 59)
Query Neighborhood Hits	87	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.117916 (rank : 57)
Query Neighborhood Hits	87	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.121559 (rank : 54)
Query Neighborhood Hits	87	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.121176 (rank : 55)
Query Neighborhood Hits	87	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.113606 (rank : 67)
Query Neighborhood Hits	87	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.113814 (rank : 65)
Query Neighborhood Hits	87	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.101649 (rank : 84)
Query Neighborhood Hits	87	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.101533 (rank : 86)
Query Neighborhood Hits	87	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.106955 (rank : 81)
Query Neighborhood Hits	87	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRD_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.071029 (rank : 102)
Query Neighborhood Hits	87	Target Neighborhood Hits	485	Shared Neighborhood Hits	11
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.068347 (rank : 104)
Query Neighborhood Hits	87	Target Neighborhood Hits	491	Shared Neighborhood Hits	10
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.102065 (rank : 83)
Query Neighborhood Hits	87	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.101537 (rank : 85)
Query Neighborhood Hits	87	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.069143 (rank : 103)
Query Neighborhood Hits	87	Target Neighborhood Hits	489	Shared Neighborhood Hits	8
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.090731 (rank : 94)
Query Neighborhood Hits	87	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.090759 (rank : 93)
Query Neighborhood Hits	87	Target Neighborhood Hits	260	Shared Neighborhood Hits	11
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.109127 (rank : 78)
Query Neighborhood Hits	87	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.109565 (rank : 72)
Query Neighborhood Hits	87	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.091542 (rank : 91)
Query Neighborhood Hits	87	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.092324 (rank : 89)
Query Neighborhood Hits	87	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.086140 (rank : 99)
Query Neighborhood Hits	87	Target Neighborhood Hits	244	Shared Neighborhood Hits	8
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.086553 (rank : 97)
Query Neighborhood Hits	87	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.113789 (rank : 66)
Query Neighborhood Hits	87	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.113550 (rank : 68)
Query Neighborhood Hits	87	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.114060 (rank : 64)
Query Neighborhood Hits	87	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.111536 (rank : 70)
Query Neighborhood Hits	87	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.111874 (rank : 69)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRS_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.072257 (rank : 101)
Query Neighborhood Hits	87	Target Neighborhood Hits	472	Shared Neighborhood Hits	8
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRT_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.088669 (rank : 95)
Query Neighborhood Hits	87	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.088531 (rank : 96)
Query Neighborhood Hits	87	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.086210 (rank : 98)
Query Neighborhood Hits	87	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.108495 (rank : 80)
Query Neighborhood Hits	87	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.091313 (rank : 92)
Query Neighborhood Hits	87	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

Hits sorted by NC score

E41LA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	87	Target Neighborhood Hits	87	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.996444 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_MOUSE
NC score	0.972385 (rank : 3)	θ value	3.45727e-76 (rank : 4)
Query Neighborhood Hits	87	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41L5_HUMAN
NC score	0.972152 (rank : 4)	θ value	5.33382e-77 (rank : 3)
Query Neighborhood Hits	87	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

FRMD5_MOUSE
NC score	0.970542 (rank : 5)	θ value	2.65329e-68 (rank : 11)
Query Neighborhood Hits	87	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.968595 (rank : 6)	θ value	2.93355e-67 (rank : 13)
Query Neighborhood Hits	87	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LB_HUMAN
NC score	0.967006 (rank : 7)	θ value	2.92676e-75 (rank : 5)
Query Neighborhood Hits	87	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41L3_HUMAN
NC score	0.958406 (rank : 8)	θ value	3.70236e-70 (rank : 7)
Query Neighborhood Hits	87	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L1_MOUSE
NC score	0.956585 (rank : 9)	θ value	1.40689e-69 (rank : 8)
Query Neighborhood Hits	87	Target Neighborhood Hits	106	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_HUMAN
NC score	0.953568 (rank : 10)	θ value	7.71989e-68 (rank : 12)
Query Neighborhood Hits	87	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L1_HUMAN
NC score	0.952151 (rank : 11)	θ value	4.09345e-69 (rank : 9)
Query Neighborhood Hits	87	Target Neighborhood Hits	180	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_MOUSE
NC score	0.950157 (rank : 12)	θ value	2.74572e-65 (rank : 14)
Query Neighborhood Hits	87	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L3_MOUSE
NC score	0.945135 (rank : 13)	θ value	1.5555e-68 (rank : 10)
Query Neighborhood Hits	87	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.940362 (rank : 14)	θ value	3.58603e-65 (rank : 15)
Query Neighborhood Hits	87	Target Neighborhood Hits	287	Shared Neighborhood Hits	53
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
NC score	0.918005 (rank : 15)	θ value	2.84138e-62 (rank : 16)
Query Neighborhood Hits	87	Target Neighborhood Hits	459	Shared Neighborhood Hits	60
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_MOUSE
NC score	0.862704 (rank : 16)	θ value	1.16704e-23 (rank : 36)
Query Neighborhood Hits	87	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.846554 (rank : 17)	θ value	1.16704e-23 (rank : 35)
Query Neighborhood Hits	87	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4B_HUMAN
NC score	0.810874 (rank : 18)	θ value	1.2077e-20 (rank : 40)
Query Neighborhood Hits	87	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.808257 (rank : 19)	θ value	9.24701e-21 (rank : 39)
Query Neighborhood Hits	87	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
NC score	0.805887 (rank : 20)	θ value	4.43474e-23 (rank : 37)
Query Neighborhood Hits	87	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
NC score	0.804877 (rank : 21)	θ value	7.56453e-23 (rank : 38)
Query Neighborhood Hits	87	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MERL_MOUSE
NC score	0.788786 (rank : 22)	θ value	1.33217e-27 (rank : 32)
Query Neighborhood Hits	87	Target Neighborhood Hits	524	Shared Neighborhood Hits	51
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

FARP1_HUMAN
NC score	0.788577 (rank : 23)	θ value	1.51363e-47 (rank : 18)
Query Neighborhood Hits	87	Target Neighborhood Hits	241	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

MERL_HUMAN
NC score	0.788070 (rank : 24)	θ value	1.02001e-27 (rank : 31)
Query Neighborhood Hits	87	Target Neighborhood Hits	532	Shared Neighborhood Hits	50
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FARP2_HUMAN
NC score	0.763844 (rank : 25)	θ value	7.27602e-42 (rank : 20)
Query Neighborhood Hits	87	Target Neighborhood Hits	240	Shared Neighborhood Hits	50
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.756131 (rank : 26)	θ value	5.95217e-44 (rank : 19)
Query Neighborhood Hits	87	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

EZRI_HUMAN
NC score	0.751994 (rank : 27)	θ value	1.98606e-31 (rank : 23)
Query Neighborhood Hits	87	Target Neighborhood Hits	663	Shared Neighborhood Hits	49
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.747338 (rank : 28)	θ value	1.98606e-31 (rank : 24)
Query Neighborhood Hits	87	Target Neighborhood Hits	693	Shared Neighborhood Hits	49
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.733382 (rank : 29)	θ value	9.8567e-31 (rank : 26)
Query Neighborhood Hits	87	Target Neighborhood Hits	741	Shared Neighborhood Hits	49
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.729733 (rank : 30)	θ value	9.8567e-31 (rank : 27)
Query Neighborhood Hits	87	Target Neighborhood Hits	773	Shared Neighborhood Hits	50
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

FRMD6_MOUSE
NC score	0.706082 (rank : 31)	θ value	4.59992e-12 (rank : 42)
Query Neighborhood Hits	87	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.700185 (rank : 32)	θ value	7.09661e-13 (rank : 41)
Query Neighborhood Hits	87	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

MOES_HUMAN
NC score	0.689017 (rank : 33)	θ value	8.3442e-30 (rank : 28)
Query Neighborhood Hits	87	Target Neighborhood Hits	892	Shared Neighborhood Hits	51
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
NC score	0.681432 (rank : 34)	θ value	8.3442e-30 (rank : 29)
Query Neighborhood Hits	87	Target Neighborhood Hits	923	Shared Neighborhood Hits	51
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN4_HUMAN
NC score	0.680963 (rank : 35)	θ value	2.47765e-74 (rank : 6)
Query Neighborhood Hits	87	Target Neighborhood Hits	303	Shared Neighborhood Hits	54
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

FRMD1_HUMAN
NC score	0.674434 (rank : 36)	θ value	1.53129e-07 (rank : 47)
Query Neighborhood Hits	87	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

PTN3_HUMAN
NC score	0.653753 (rank : 37)	θ value	2.1121e-49 (rank : 17)
Query Neighborhood Hits	87	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN21_MOUSE
NC score	0.627659 (rank : 38)	θ value	2.77131e-33 (rank : 21)
Query Neighborhood Hits	87	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.625575 (rank : 39)	θ value	1.79631e-32 (rank : 22)
Query Neighborhood Hits	87	Target Neighborhood Hits	143	Shared Neighborhood Hits	47
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.612848 (rank : 40)	θ value	5.77852e-31 (rank : 25)
Query Neighborhood Hits	87	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.604937 (rank : 41)	θ value	1.85889e-29 (rank : 30)
Query Neighborhood Hits	87	Target Neighborhood Hits	163	Shared Neighborhood Hits	51
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.498954 (rank : 42)	θ value	8.63488e-27 (rank : 34)
Query Neighborhood Hits	87	Target Neighborhood Hits	426	Shared Neighborhood Hits	54
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.489529 (rank : 43)	θ value	2.27234e-27 (rank : 33)
Query Neighborhood Hits	87	Target Neighborhood Hits	471	Shared Neighborhood Hits	56
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

TLN1_HUMAN
NC score	0.447588 (rank : 44)	θ value	1.63604e-09 (rank : 45)
Query Neighborhood Hits	87	Target Neighborhood Hits	218	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.446148 (rank : 45)	θ value	1.25267e-09 (rank : 44)
Query Neighborhood Hits	87	Target Neighborhood Hits	149	Shared Neighborhood Hits	48
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_MOUSE
NC score	0.444518 (rank : 46)	θ value	1.63604e-09 (rank : 46)
Query Neighborhood Hits	87	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
NC score	0.441439 (rank : 47)	θ value	9.59137e-10 (rank : 43)
Query Neighborhood Hits	87	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

PTN2_MOUSE
NC score	0.127180 (rank : 48)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	87	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.126236 (rank : 49)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN18_HUMAN
NC score	0.125965 (rank : 50)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	87	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN2_HUMAN
NC score	0.125848 (rank : 51)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	87	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN1_HUMAN
NC score	0.125843 (rank : 52)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_MOUSE
NC score	0.122098 (rank : 53)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	87	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
NC score	0.121559 (rank : 54)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	87	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
NC score	0.121176 (rank : 55)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	87	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_HUMAN
NC score	0.119530 (rank : 56)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	87	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN7_MOUSE
NC score	0.117916 (rank : 57)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	87	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN22_MOUSE
NC score	0.117665 (rank : 58)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	87	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN7_HUMAN
NC score	0.116660 (rank : 59)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	87	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN12_HUMAN
NC score	0.116522 (rank : 60)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	87	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
NC score	0.116510 (rank : 61)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	87	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN6_HUMAN
NC score	0.116421 (rank : 62)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	87	Target Neighborhood Hits	234	Shared Neighborhood Hits	8
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
NC score	0.116403 (rank : 63)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	87	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRO_HUMAN
NC score	0.114060 (rank : 64)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	87	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPR2_MOUSE
NC score	0.113814 (rank : 65)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	87	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRN_HUMAN
NC score	0.113789 (rank : 66)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	87	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPR2_HUMAN
NC score	0.113606 (rank : 67)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	87	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRN_MOUSE
NC score	0.113550 (rank : 68)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	87	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_MOUSE
NC score	0.111874 (rank : 69)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.111536 (rank : 70)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	87	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

CD45_MOUSE
NC score	0.110104 (rank : 71)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	87	Target Neighborhood Hits	178	Shared Neighborhood Hits	11
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRJ_MOUSE
NC score	0.109565 (rank : 72)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	87	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN23_HUMAN
NC score	0.109529 (rank : 73)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	87	Target Neighborhood Hits	646	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN11_MOUSE
NC score	0.109518 (rank : 74)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	87	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.109511 (rank : 75)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	87	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN5_HUMAN
NC score	0.109458 (rank : 76)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	87	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
NC score	0.109414 (rank : 77)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRJ_HUMAN
NC score	0.109127 (rank : 78)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	87	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN23_MOUSE
NC score	0.108537 (rank : 79)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	87	Target Neighborhood Hits	726	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTPRV_MOUSE
NC score	0.108495 (rank : 80)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	87	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRB_HUMAN
NC score	0.106955 (rank : 81)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	87	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

CD45_HUMAN
NC score	0.105499 (rank : 82)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	87	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRE_HUMAN
NC score	0.102065 (rank : 83)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	87	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.101649 (rank : 84)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	87	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRE_MOUSE
NC score	0.101537 (rank : 85)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	87	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_MOUSE
NC score	0.101533 (rank : 86)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	87	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

CA106_HUMAN
NC score	0.096977 (rank : 87)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	87	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
NC score	0.095638 (rank : 88)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	87	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

PTPRK_MOUSE
NC score	0.092324 (rank : 89)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	87	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

KRIT1_HUMAN
NC score	0.091640 (rank : 90)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	87	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

PTPRK_HUMAN
NC score	0.091542 (rank : 91)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	87	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRZ_HUMAN
NC score	0.091313 (rank : 92)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	87	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_MOUSE
NC score	0.090759 (rank : 93)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	87	Target Neighborhood Hits	260	Shared Neighborhood Hits	11
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_HUMAN
NC score	0.090731 (rank : 94)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	87	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRT_HUMAN
NC score	0.088669 (rank : 95)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	87	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.088531 (rank : 96)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	87	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRM_MOUSE
NC score	0.086553 (rank : 97)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	87	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
NC score	0.086210 (rank : 98)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	87	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_HUMAN
NC score	0.086140 (rank : 99)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	87	Target Neighborhood Hits	244	Shared Neighborhood Hits	8
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

KRIT1_MOUSE
NC score	0.084862 (rank : 100)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	87	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PTPRS_HUMAN
NC score	0.072257 (rank : 101)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	87	Target Neighborhood Hits	472	Shared Neighborhood Hits	8
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRD_HUMAN
NC score	0.071029 (rank : 102)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	87	Target Neighborhood Hits	485	Shared Neighborhood Hits	11
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.069143 (rank : 103)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	87	Target Neighborhood Hits	489	Shared Neighborhood Hits	8
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.068347 (rank : 104)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	87	Target Neighborhood Hits	491	Shared Neighborhood Hits	10
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

MESD1_MOUSE
NC score	0.063528 (rank : 105)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	87	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_HUMAN
NC score	0.061787 (rank : 106)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	87	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

HIP1R_HUMAN
NC score	0.059935 (rank : 107)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	87	Target Neighborhood Hits	809	Shared Neighborhood Hits	20
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1_HUMAN
NC score	0.059072 (rank : 108)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	87	Target Neighborhood Hits	1016	Shared Neighborhood Hits	21
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

FGD5_HUMAN
NC score	0.058411 (rank : 109)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	87	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD6_MOUSE
NC score	0.057140 (rank : 110)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	87	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD6_HUMAN
NC score	0.056949 (rank : 111)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	87	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

HIP1R_MOUSE
NC score	0.055479 (rank : 112)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	87	Target Neighborhood Hits	959	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

FGD4_MOUSE
NC score	0.055456 (rank : 113)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	87	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD5_MOUSE
NC score	0.054994 (rank : 114)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	87	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD4_HUMAN
NC score	0.054986 (rank : 115)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	87	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD1_HUMAN
NC score	0.054663 (rank : 116)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	87	Target Neighborhood Hits	367	Shared Neighborhood Hits	10
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PHF20_MOUSE
NC score	0.054037 (rank : 117)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	87	Target Neighborhood Hits	513	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

FGD1_MOUSE
NC score	0.052267 (rank : 118)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	87	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

NPBL_MOUSE
NC score	0.052134 (rank : 119)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	87	Target Neighborhood Hits	1041	Shared Neighborhood Hits	35
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.051307 (rank : 120)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	87	Target Neighborhood Hits	1311	Shared Neighborhood Hits	37
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PKHA6_MOUSE
NC score	0.051131 (rank : 121)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	87	Target Neighborhood Hits	591	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

WAPL_HUMAN
NC score	0.047249 (rank : 122)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	87	Target Neighborhood Hits	122	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

WAPL_MOUSE
NC score	0.047144 (rank : 123)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	87	Target Neighborhood Hits	158	Shared Neighborhood Hits	11
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

PAR3L_HUMAN
NC score	0.044639 (rank : 124)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	87	Target Neighborhood Hits	297	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

TARA_MOUSE
NC score	0.040706 (rank : 125)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	87	Target Neighborhood Hits	1133	Shared Neighborhood Hits	29
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZO2_HUMAN
NC score	0.039506 (rank : 126)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	87	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

IWS1_HUMAN
NC score	0.039462 (rank : 127)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	87	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SRRM2_HUMAN
NC score	0.038257 (rank : 128)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	87	Target Neighborhood Hits	1296	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PHF20_HUMAN
NC score	0.035629 (rank : 129)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	87	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

NCOR1_MOUSE
NC score	0.034702 (rank : 130)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	87	Target Neighborhood Hits	521	Shared Neighborhood Hits	25
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

TXND2_MOUSE
NC score	0.033412 (rank : 131)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	87	Target Neighborhood Hits	828	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

SFRIP_HUMAN
NC score	0.032448 (rank : 132)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	87	Target Neighborhood Hits	530	Shared Neighborhood Hits	21
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

PCLO_MOUSE
NC score	0.031576 (rank : 133)	θ value	0.0113563 (rank : 48)
Query Neighborhood Hits	87	Target Neighborhood Hits	2275	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCLO_HUMAN
NC score	0.029512 (rank : 134)	θ value	0.0563607 (rank : 51)
Query Neighborhood Hits	87	Target Neighborhood Hits	2046	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SRRM2_MOUSE
NC score	0.027257 (rank : 135)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	87	Target Neighborhood Hits	1470	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM1_MOUSE
NC score	0.026235 (rank : 136)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	87	Target Neighborhood Hits	966	Shared Neighborhood Hits	23
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CTR9_MOUSE
NC score	0.022024 (rank : 137)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	87	Target Neighborhood Hits	427	Shared Neighborhood Hits	15
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

SRRM1_HUMAN
NC score	0.021342 (rank : 138)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	87	Target Neighborhood Hits	690	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

STOX1_HUMAN
NC score	0.021013 (rank : 139)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	87	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZVD7, Q4F8Q6, Q5I946, Q5I947, Q5I948, Q5VX38, Q5VX39, Q6ZRY3, Q96LR3, Q96LS0	Gene names	STOX1, C10orf24
Domain Architecture	No domain graphic available
Description	Storkhead-box protein 1 (Winged helix domain-containing protein).

TCOF_HUMAN
NC score	0.020783 (rank : 140)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	87	Target Neighborhood Hits	543	Shared Neighborhood Hits	17
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

FUSIP_HUMAN
NC score	0.019180 (rank : 141)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	87	Target Neighborhood Hits	230	Shared Neighborhood Hits	12
SwissProt Accessions	O75494, O60572, Q96G09, Q96P17	Gene names	FUSIP1, TASR
Domain Architecture
Description	FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (40 kDa SR-repressor protein) (SRrp40) (Splicing factor SRp38).

FUSIP_MOUSE
NC score	0.019180 (rank : 142)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	87	Target Neighborhood Hits	230	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R0U0, O70307, O88468, Q3TGW7, Q8CFZ1, Q9R0T9	Gene names	Fusip1, Nssr
Domain Architecture
Description	FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (Neural-specific SR protein) (Neural-salient serine/arginine-rich protein).

CE290_HUMAN
NC score	0.015692 (rank : 143)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	87	Target Neighborhood Hits	1553	Shared Neighborhood Hits	19
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

DDX21_HUMAN
NC score	0.014524 (rank : 144)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	87	Target Neighborhood Hits	308	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

WDHD1_MOUSE
NC score	0.014055 (rank : 145)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	87	Target Neighborhood Hits	414	Shared Neighborhood Hits	10
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

NKTR_HUMAN
NC score	0.013971 (rank : 146)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	87	Target Neighborhood Hits	658	Shared Neighborhood Hits	27
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

MRCKB_HUMAN
NC score	0.012988 (rank : 147)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	87	Target Neighborhood Hits	2239	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MIER1_MOUSE
NC score	0.010541 (rank : 148)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

BCOR_HUMAN
NC score	0.009891 (rank : 149)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	87	Target Neighborhood Hits	609	Shared Neighborhood Hits	13
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

PO121_HUMAN
NC score	0.009402 (rank : 150)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	87	Target Neighborhood Hits	344	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

BCOR_MOUSE
NC score	0.007722 (rank : 151)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	87	Target Neighborhood Hits	521	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

YETS2_HUMAN
NC score	0.007087 (rank : 152)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	87	Target Neighborhood Hits	212	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

KBTBA_HUMAN
NC score	0.004262 (rank : 153)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	87	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

ZN512_HUMAN
NC score	0.001190 (rank : 154)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	87	Target Neighborhood Hits	444	Shared Neighborhood Hits	2
SwissProt Accessions	Q96ME7, Q96JM0	Gene names	ZNF512, KIAA1805
Domain Architecture	No domain graphic available
Description	Zinc finger protein 512.

ABCA4_MOUSE
NC score	0.001159 (rank : 155)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	87	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

SRPK1_MOUSE
NC score	0.001104 (rank : 156)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	87	Target Neighborhood Hits	639	Shared Neighborhood Hits	7
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

SPG16_HUMAN
NC score	-0.001108 (rank : 157)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	87	Target Neighborhood Hits	361	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

AKT2_HUMAN
NC score	-0.004883 (rank : 158)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	87	Target Neighborhood Hits	878	Shared Neighborhood Hits	4
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).